diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index 5e6e9a63..c547f50b 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -6,6 +6,10 @@ All notable changes to this project will be documented in this file.
 
 The format is based on `Keep a Changelog <https://keepachangelog.com>`_.
 
+6.10
+----
+- In ``lineplot_and_heatmap``, mutations that are hidden are by one slider filtered even if they fail other sliders. Addresses `this issue <https://github.com/dms-vep/dms-vep-pipeline-3/issues/96>`_
+
 6.9
 ---
 - Added ``rename_std`` option to ``lineplot_and_heatmaps``, which fixes a quasi-bug introduced in the ``rename_stat_col`` option by the changes in version 6.8.
diff --git a/notebooks/real_LyCoV1404.ipynb b/notebooks/real_LyCoV1404.ipynb
index d9fd8603..6c7461c6 100644
--- a/notebooks/real_LyCoV1404.ipynb
+++ b/notebooks/real_LyCoV1404.ipynb
@@ -17,13 +17,6 @@
    "execution_count": 1,
    "id": "0b46edd2",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:33:25.819279Z",
-     "iopub.status.busy": "2023-08-18T19:33:25.818688Z",
-     "iopub.status.idle": "2023-08-18T19:33:29.522502Z",
-     "shell.execute_reply": "2023-08-18T19:33:29.521326Z",
-     "shell.execute_reply.started": "2023-08-18T19:33:25.819250Z"
-    },
     "tags": []
    },
    "outputs": [],
@@ -52,13 +45,6 @@
    "execution_count": 2,
    "id": "46127941",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:33:29.527470Z",
-     "iopub.status.busy": "2023-08-18T19:33:29.527103Z",
-     "iopub.status.idle": "2023-08-18T19:33:30.072992Z",
-     "shell.execute_reply": "2023-08-18T19:33:30.072145Z",
-     "shell.execute_reply.started": "2023-08-18T19:33:29.527439Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -226,13 +212,6 @@
    "execution_count": 3,
    "id": "ad21ccc1",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:33:30.076244Z",
-     "iopub.status.busy": "2023-08-18T19:33:30.075996Z",
-     "iopub.status.idle": "2023-08-18T19:33:30.220143Z",
-     "shell.execute_reply": "2023-08-18T19:33:30.219397Z",
-     "shell.execute_reply.started": "2023-08-18T19:33:30.076223Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -355,13 +334,6 @@
    "execution_count": 4,
    "id": "2646efb0",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:33:30.221417Z",
-     "iopub.status.busy": "2023-08-18T19:33:30.221143Z",
-     "iopub.status.idle": "2023-08-18T19:33:30.445033Z",
-     "shell.execute_reply": "2023-08-18T19:33:30.443911Z",
-     "shell.execute_reply.started": "2023-08-18T19:33:30.221397Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -370,28 +342,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-9b1b8915c2de4f26981285e4636187f4.vega-embed {\n",
+       "  #altair-viz-e3f62fa563bb488a8ff69c500e6234a8.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-9b1b8915c2de4f26981285e4636187f4.vega-embed details,\n",
-       "  #altair-viz-9b1b8915c2de4f26981285e4636187f4.vega-embed details summary {\n",
+       "  #altair-viz-e3f62fa563bb488a8ff69c500e6234a8.vega-embed details,\n",
+       "  #altair-viz-e3f62fa563bb488a8ff69c500e6234a8.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-9b1b8915c2de4f26981285e4636187f4\"></div>\n",
+       "<div id=\"altair-viz-e3f62fa563bb488a8ff69c500e6234a8\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-9b1b8915c2de4f26981285e4636187f4\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-9b1b8915c2de4f26981285e4636187f4\");\n",
+       "    if (outputDiv.id !== \"altair-viz-e3f62fa563bb488a8ff69c500e6234a8\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-e3f62fa563bb488a8ff69c500e6234a8\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -427,12 +399,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"data\": {\"name\": \"data-3b0145c734c929ff834e40e47fa96f4f\"}, \"mark\": {\"type\": \"line\", \"point\": true, \"size\": 0.5}, \"encoding\": {\"color\": {\"field\": \"n_subs\", \"title\": \"n substitutions\", \"type\": \"nominal\"}, \"column\": {\"field\": \"censored\", \"title\": null, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"antibody_concentration\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_subs\", \"type\": \"nominal\"}, {\"field\": \"censored\", \"type\": \"nominal\"}, {\"field\": \"probability escape\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"antibody_concentration\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"probability escape\", \"scale\": {\"constant\": 0.05, \"type\": \"symlog\"}, \"type\": \"quantitative\"}}, \"height\": 125, \"width\": 200, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-3b0145c734c929ff834e40e47fa96f4f\": [{\"antibody_concentration\": 0.654, \"n_subs\": \"0\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.025597568620806508}, {\"antibody_concentration\": 0.654, \"n_subs\": \"1\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.03373648999413883}, {\"antibody_concentration\": 0.654, \"n_subs\": \"2\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04213001015572106}, {\"antibody_concentration\": 0.654, \"n_subs\": \"3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04972390620362125}, {\"antibody_concentration\": 0.654, \"n_subs\": \">3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.05742010028529437}, {\"antibody_concentration\": 2.616, \"n_subs\": \"0\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.022157302609284987}, {\"antibody_concentration\": 2.616, \"n_subs\": \"1\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.029215040888665604}, {\"antibody_concentration\": 2.616, \"n_subs\": \"2\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.034829989844278944}, {\"antibody_concentration\": 2.616, \"n_subs\": \"3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04034192935589195}, {\"antibody_concentration\": 2.616, \"n_subs\": \">3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04870542923835049}, {\"antibody_concentration\": 10.46, \"n_subs\": \"0\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.011939384954252796}, {\"antibody_concentration\": 10.46, \"n_subs\": \"1\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.018166203354824304}, {\"antibody_concentration\": 10.46, \"n_subs\": \"2\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.024517369668246445}, {\"antibody_concentration\": 10.46, \"n_subs\": \"3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.030345746512318195}, {\"antibody_concentration\": 10.46, \"n_subs\": \">3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04253981153280885}, {\"antibody_concentration\": 0.654, \"n_subs\": \"0\", \"censored\": \"not censored\", \"probability escape\": 0.025933725855642152}, {\"antibody_concentration\": 0.654, \"n_subs\": \"1\", \"censored\": \"not censored\", \"probability escape\": 0.03733276675318876}, {\"antibody_concentration\": 0.654, \"n_subs\": \"2\", \"censored\": \"not censored\", \"probability escape\": 0.049703774542992546}, {\"antibody_concentration\": 0.654, \"n_subs\": \"3\", \"censored\": \"not censored\", \"probability escape\": 0.06209422380528347}, {\"antibody_concentration\": 0.654, \"n_subs\": \">3\", \"censored\": \"not censored\", \"probability escape\": 0.07284060689893662}, {\"antibody_concentration\": 2.616, \"n_subs\": \"0\", \"censored\": \"not censored\", \"probability escape\": 0.023078769908505593}, {\"antibody_concentration\": 2.616, \"n_subs\": \"1\", \"censored\": \"not censored\", \"probability escape\": 0.034174849981858275}, {\"antibody_concentration\": 2.616, \"n_subs\": \"2\", \"censored\": \"not censored\", \"probability escape\": 0.043554329722410294}, {\"antibody_concentration\": 2.616, \"n_subs\": \"3\", \"censored\": \"not censored\", \"probability escape\": 0.05453094686850698}, {\"antibody_concentration\": 2.616, \"n_subs\": \">3\", \"censored\": \"not censored\", \"probability escape\": 0.07376300682977435}, {\"antibody_concentration\": 10.46, \"n_subs\": \"0\", \"censored\": \"not censored\", \"probability escape\": 0.012332048458149778}, {\"antibody_concentration\": 10.46, \"n_subs\": \"1\", \"censored\": \"not censored\", \"probability escape\": 0.02057182449970694}, {\"antibody_concentration\": 10.46, \"n_subs\": \"2\", \"censored\": \"not censored\", \"probability escape\": 0.028375155721056193}, {\"antibody_concentration\": 10.46, \"n_subs\": \"3\", \"censored\": \"not censored\", \"probability escape\": 0.03622808548530722}, {\"antibody_concentration\": 10.46, \"n_subs\": \">3\", \"censored\": \"not censored\", \"probability escape\": 0.0548717904383159}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"data\": {\"name\": \"data-3b0145c734c929ff834e40e47fa96f4f\"}, \"mark\": {\"type\": \"line\", \"point\": true, \"size\": 0.5}, \"encoding\": {\"color\": {\"field\": \"n_subs\", \"title\": \"n substitutions\", \"type\": \"nominal\"}, \"column\": {\"field\": \"censored\", \"title\": null, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"antibody_concentration\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_subs\", \"type\": \"nominal\"}, {\"field\": \"censored\", \"type\": \"nominal\"}, {\"field\": \"probability escape\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"antibody_concentration\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"probability escape\", \"scale\": {\"constant\": 0.05, \"type\": \"symlog\"}, \"type\": \"quantitative\"}}, \"height\": 125, \"width\": 200, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-3b0145c734c929ff834e40e47fa96f4f\": [{\"antibody_concentration\": 0.654, \"n_subs\": \"0\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.025597568620806508}, {\"antibody_concentration\": 0.654, \"n_subs\": \"1\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.03373648999413883}, {\"antibody_concentration\": 0.654, \"n_subs\": \"2\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04213001015572106}, {\"antibody_concentration\": 0.654, \"n_subs\": \"3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04972390620362125}, {\"antibody_concentration\": 0.654, \"n_subs\": \">3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.05742010028529437}, {\"antibody_concentration\": 2.616, \"n_subs\": \"0\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.022157302609284987}, {\"antibody_concentration\": 2.616, \"n_subs\": \"1\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.029215040888665604}, {\"antibody_concentration\": 2.616, \"n_subs\": \"2\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.034829989844278944}, {\"antibody_concentration\": 2.616, \"n_subs\": \"3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04034192935589195}, {\"antibody_concentration\": 2.616, \"n_subs\": \">3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04870542923835049}, {\"antibody_concentration\": 10.46, \"n_subs\": \"0\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.011939384954252796}, {\"antibody_concentration\": 10.46, \"n_subs\": \"1\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.018166203354824304}, {\"antibody_concentration\": 10.46, \"n_subs\": \"2\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.024517369668246445}, {\"antibody_concentration\": 10.46, \"n_subs\": \"3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.030345746512318195}, {\"antibody_concentration\": 10.46, \"n_subs\": \">3\", \"censored\": \"censored to [0, 1]\", \"probability escape\": 0.04253981153280885}, {\"antibody_concentration\": 0.654, \"n_subs\": \"0\", \"censored\": \"not censored\", \"probability escape\": 0.025933725855642152}, {\"antibody_concentration\": 0.654, \"n_subs\": \"1\", \"censored\": \"not censored\", \"probability escape\": 0.03733276675318876}, {\"antibody_concentration\": 0.654, \"n_subs\": \"2\", \"censored\": \"not censored\", \"probability escape\": 0.049703774542992546}, {\"antibody_concentration\": 0.654, \"n_subs\": \"3\", \"censored\": \"not censored\", \"probability escape\": 0.06209422380528347}, {\"antibody_concentration\": 0.654, \"n_subs\": \">3\", \"censored\": \"not censored\", \"probability escape\": 0.07284060689893662}, {\"antibody_concentration\": 2.616, \"n_subs\": \"0\", \"censored\": \"not censored\", \"probability escape\": 0.023078769908505593}, {\"antibody_concentration\": 2.616, \"n_subs\": \"1\", \"censored\": \"not censored\", \"probability escape\": 0.034174849981858275}, {\"antibody_concentration\": 2.616, \"n_subs\": \"2\", \"censored\": \"not censored\", \"probability escape\": 0.043554329722410294}, {\"antibody_concentration\": 2.616, \"n_subs\": \"3\", \"censored\": \"not censored\", \"probability escape\": 0.05453094686850698}, {\"antibody_concentration\": 2.616, \"n_subs\": \">3\", \"censored\": \"not censored\", \"probability escape\": 0.07376300682977435}, {\"antibody_concentration\": 10.46, \"n_subs\": \"0\", \"censored\": \"not censored\", \"probability escape\": 0.012332048458149778}, {\"antibody_concentration\": 10.46, \"n_subs\": \"1\", \"censored\": \"not censored\", \"probability escape\": 0.02057182449970694}, {\"antibody_concentration\": 10.46, \"n_subs\": \"2\", \"censored\": \"not censored\", \"probability escape\": 0.028375155721056193}, {\"antibody_concentration\": 10.46, \"n_subs\": \"3\", \"censored\": \"not censored\", \"probability escape\": 0.03622808548530722}, {\"antibody_concentration\": 10.46, \"n_subs\": \">3\", \"censored\": \"not censored\", \"probability escape\": 0.0548717904383159}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -518,13 +490,6 @@
    "execution_count": 5,
    "id": "9d265060",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:33:30.446982Z",
-     "iopub.status.busy": "2023-08-18T19:33:30.446468Z",
-     "iopub.status.idle": "2023-08-18T19:35:53.622894Z",
-     "shell.execute_reply": "2023-08-18T19:35:53.622142Z",
-     "shell.execute_reply.started": "2023-08-18T19:33:30.446942Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -534,28 +499,28 @@
      "text": [
       "#\n",
       "# Fitting site-level fixed Hill coefficient and non-neutralized frac model.\n",
-      "# Starting optimization of 1248 parameters at Fri Aug 18 12:33:36 2023.\n",
+      "# Starting optimization of 1248 parameters at Fri Jan 26 11:43:31 2024.\n",
       "        step    time_sec        loss    fit_loss  reg_escape  reg_spread reg_spatial reg_uniqueness reg_uniqueness2 reg_activity reg_hill_coefficient reg_non_neutralized_frac\n",
-      "           0    0.080992       37333       37314           0           0           0              0               0       18.641                    0                        0\n",
-      "         100       8.954        4910        4825      38.888           0           0              0               0       46.108                    0                        0\n",
-      "         177      15.898      4908.2      4822.5      39.589           0           0              0               0       46.145                    0                        0\n",
-      "# Successfully finished at Fri Aug 18 12:33:52 2023.\n",
+      "           0    0.036176       37333       37314           0           0           0              0               0       18.641                    0                        0\n",
+      "         100      4.0581        4910        4825      38.903           0           0              0               0       46.113                    0                        0\n",
+      "         187      7.4821      4908.2      4822.4      39.676           0           0              0               0       46.145                    0                        0\n",
+      "# Successfully finished at Fri Jan 26 11:43:39 2024.\n",
       "#\n",
       "# Fitting fixed Hill coefficient and non-neutralized frac model.\n",
-      "# Starting optimization of 8450 parameters at Fri Aug 18 12:33:52 2023.\n",
+      "# Starting optimization of 8450 parameters at Fri Jan 26 11:43:39 2024.\n",
       "        step    time_sec        loss    fit_loss  reg_escape  reg_spread reg_spatial reg_uniqueness reg_uniqueness2 reg_activity reg_hill_coefficient reg_non_neutralized_frac\n",
-      "           0      0.2196      7347.8      7034.8      266.82  3.6355e-31           0              0               0       46.145                    0                        0\n",
-      "         100      44.671      6864.9      6706.7      95.063      10.674           0              0               0       52.402                    0                        0\n",
-      "         200      86.329      6855.5      6701.8      89.625      11.611           0              0               0       52.473                    0                        0\n",
-      "         265      112.06      6854.7      6701.4      89.038      11.746           0              0               0       52.456                    0                        0\n",
-      "# Successfully finished at Fri Aug 18 12:35:44 2023.\n",
+      "           0    0.057451      7348.1      7034.8      267.14  2.8796e-31           0              0               0       46.145                    0                        0\n",
+      "         100      6.7995        6863      6706.2      93.396        10.9           0              0               0       52.517                    0                        0\n",
+      "         200      13.405        6855      6701.6      89.267      11.691           0              0               0       52.449                    0                        0\n",
+      "         221      14.788      6854.7      6701.6      88.939      11.715           0              0               0       52.465                    0                        0\n",
+      "# Successfully finished at Fri Jan 26 11:43:54 2024.\n",
       "#\n",
       "# Fitting model.\n",
-      "# Starting optimization of 8452 parameters at Fri Aug 18 12:35:44 2023.\n",
+      "# Starting optimization of 8452 parameters at Fri Jan 26 11:43:54 2024.\n",
       "        step    time_sec        loss    fit_loss  reg_escape  reg_spread reg_spatial reg_uniqueness reg_uniqueness2 reg_activity reg_hill_coefficient reg_non_neutralized_frac\n",
-      "           0     0.29954      6812.7      6701.4      89.038      11.746           0              0               0       10.491                    0                        0\n",
-      "          19      9.0023      6750.3      6638.1      89.041      11.747           0              0               0       10.444              0.90715                 0.076633\n",
-      "# Successfully finished at Fri Aug 18 12:35:53 2023.\n"
+      "           0    0.056528      6812.7      6701.6      88.939      11.715           0              0               0       10.493                    0                        0\n",
+      "          15     0.95641      6750.3      6638.2      88.941      11.716           0              0               0       10.443              0.90755                  0.07658\n",
+      "# Successfully finished at Fri Jan 26 11:43:55 2024.\n"
      ]
     }
    ],
@@ -593,13 +558,6 @@
    "execution_count": 6,
    "id": "8e887519",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:35:53.624320Z",
-     "iopub.status.busy": "2023-08-18T19:35:53.624115Z",
-     "iopub.status.idle": "2023-08-18T19:35:53.641780Z",
-     "shell.execute_reply": "2023-08-18T19:35:53.641038Z",
-     "shell.execute_reply.started": "2023-08-18T19:35:53.624294Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -673,13 +631,6 @@
    "execution_count": 7,
    "id": "d7b168a4",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:35:53.642927Z",
-     "iopub.status.busy": "2023-08-18T19:35:53.642623Z",
-     "iopub.status.idle": "2023-08-18T19:35:53.646142Z",
-     "shell.execute_reply": "2023-08-18T19:35:53.645459Z",
-     "shell.execute_reply.started": "2023-08-18T19:35:53.642906Z"
-    },
     "tags": []
    },
    "outputs": [],
@@ -701,13 +652,6 @@
    "execution_count": 8,
    "id": "f7db9fc1-1a45-403e-b504-6cbc02f68af7",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:35:53.647243Z",
-     "iopub.status.busy": "2023-08-18T19:35:53.646964Z",
-     "iopub.status.idle": "2023-08-18T19:35:53.672204Z",
-     "shell.execute_reply": "2023-08-18T19:35:53.671606Z",
-     "shell.execute_reply.started": "2023-08-18T19:35:53.647224Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -817,13 +761,6 @@
    "execution_count": 9,
    "id": "1a9d6f5d",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:35:53.673295Z",
-     "iopub.status.busy": "2023-08-18T19:35:53.673036Z",
-     "iopub.status.idle": "2023-08-18T19:35:56.080657Z",
-     "shell.execute_reply": "2023-08-18T19:35:56.079640Z",
-     "shell.execute_reply.started": "2023-08-18T19:35:53.673278Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -832,28 +769,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-b8bbb381d0ff4335a43357cd52cd0238.vega-embed {\n",
+       "  #altair-viz-96362a108c804f378035ff6c3c29a700.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-b8bbb381d0ff4335a43357cd52cd0238.vega-embed details,\n",
-       "  #altair-viz-b8bbb381d0ff4335a43357cd52cd0238.vega-embed details summary {\n",
+       "  #altair-viz-96362a108c804f378035ff6c3c29a700.vega-embed details,\n",
+       "  #altair-viz-96362a108c804f378035ff6c3c29a700.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-b8bbb381d0ff4335a43357cd52cd0238\"></div>\n",
+       "<div id=\"altair-viz-96362a108c804f378035ff6c3c29a700\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-b8bbb381d0ff4335a43357cd52cd0238\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-b8bbb381d0ff4335a43357cd52cd0238\");\n",
+       "    if (outputDiv.id !== \"altair-viz-96362a108c804f378035ff6c3c29a700\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-96362a108c804f378035ff6c3c29a700\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -889,12 +826,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_2\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_1\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.603374897488893,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_3['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_4\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.603374897488893,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_3['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-8e525cfd471f5c22b57d18fa5797760e\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_3\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.603374897488893,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_3['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.603374897488893,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_3['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 6.9968035172164935, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.603374897488893,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_3['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.603374897488893,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_3['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-8e525cfd471f5c22b57d18fa5797760e\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_5\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_2\", \"view_1\", \"view_3\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_1\"]}, {\"name\": \"param_4\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_1\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -4.603374897488893], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_2\", \"view_1\", \"view_3\"]}, {\"name\": \"param_1\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 1.5161, \"min\": -3.3409, \"name\": \"minimum functional effect\"}, \"value\": [{\"cutoff\": -3.3409}], \"views\": [\"view_2\", \"view_1\", \"view_3\"]}, {\"name\": \"param_2\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": [{\"cutoff\": 1}], \"views\": [\"view_2\", \"view_1\", \"view_3\"]}, {\"name\": \"param_3\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 6.9968035172164935, \"min\": -4.603374897488893, \"name\": \"minimum max of escape at site\"}, \"value\": [{\"cutoff\": -4.603374897488893}], \"views\": [\"view_2\", \"view_1\", \"view_3\"]}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-9631765c1c8eedabe994b76062594ede\": [{\"site\": 1, \"_stat_site_order\": 0}, {\"site\": 2, \"_stat_site_order\": 1}, {\"site\": 3, \"_stat_site_order\": 2}, {\"site\": 4, \"_stat_site_order\": 3}, {\"site\": 5, \"_stat_site_order\": 4}, {\"site\": 6, \"_stat_site_order\": 5}, {\"site\": 7, \"_stat_site_order\": 6}, {\"site\": 8, \"_stat_site_order\": 7}, {\"site\": 9, \"_stat_site_order\": 8}, {\"site\": 10, \"_stat_site_order\": 9}, {\"site\": 11, \"_stat_site_order\": 10}, {\"site\": 12, \"_stat_site_order\": 11}, {\"site\": 13, \"_stat_site_order\": 12}, {\"site\": 14, \"_stat_site_order\": 13}, {\"site\": 15, \"_stat_site_order\": 14}, {\"site\": 16, \"_stat_site_order\": 15}, {\"site\": 17, \"_stat_site_order\": 16}, {\"site\": 18, \"_stat_site_order\": 17}, {\"site\": 19, \"_stat_site_order\": 18}, {\"site\": 20, \"_stat_site_order\": 19}, {\"site\": 21, \"_stat_site_order\": 20}, {\"site\": 22, \"_stat_site_order\": 21}, {\"site\": 23, \"_stat_site_order\": 22}, {\"site\": 24, \"_stat_site_order\": 23}, {\"site\": 25, \"_stat_site_order\": 24}, {\"site\": 26, \"_stat_site_order\": 25}, {\"site\": 27, \"_stat_site_order\": 26}, {\"site\": 28, \"_stat_site_order\": 27}, {\"site\": 29, \"_stat_site_order\": 28}, {\"site\": 30, \"_stat_site_order\": 29}, {\"site\": 31, \"_stat_site_order\": 30}, {\"site\": 32, \"_stat_site_order\": 31}, {\"site\": 33, \"_stat_site_order\": 32}, {\"site\": 34, \"_stat_site_order\": 33}, {\"site\": 35, \"_stat_site_order\": 34}, {\"site\": 36, \"_stat_site_order\": 35}, {\"site\": 37, \"_stat_site_order\": 36}, {\"site\": 38, \"_stat_site_order\": 37}, {\"site\": 39, \"_stat_site_order\": 38}, {\"site\": 40, \"_stat_site_order\": 39}, {\"site\": 41, \"_stat_site_order\": 40}, {\"site\": 42, \"_stat_site_order\": 41}, {\"site\": 43, \"_stat_site_order\": 42}, {\"site\": 44, \"_stat_site_order\": 43}, {\"site\": 45, \"_stat_site_order\": 44}, {\"site\": 46, \"_stat_site_order\": 45}, {\"site\": 47, \"_stat_site_order\": 46}, {\"site\": 48, \"_stat_site_order\": 47}, {\"site\": 49, \"_stat_site_order\": 48}, {\"site\": 50, \"_stat_site_order\": 49}, {\"site\": 51, \"_stat_site_order\": 50}, {\"site\": 52, \"_stat_site_order\": 51}, {\"site\": 53, \"_stat_site_order\": 52}, {\"site\": 54, \"_stat_site_order\": 53}, {\"site\": 55, \"_stat_site_order\": 54}, {\"site\": 56, \"_stat_site_order\": 55}, {\"site\": 57, \"_stat_site_order\": 56}, {\"site\": 58, \"_stat_site_order\": 57}, {\"site\": 59, \"_stat_site_order\": 58}, {\"site\": 60, \"_stat_site_order\": 59}, {\"site\": 61, \"_stat_site_order\": 60}, {\"site\": 62, \"_stat_site_order\": 61}, {\"site\": 63, \"_stat_site_order\": 62}, {\"site\": 64, \"_stat_site_order\": 63}, {\"site\": 65, \"_stat_site_order\": 64}, {\"site\": 66, \"_stat_site_order\": 65}, {\"site\": 67, \"_stat_site_order\": 66}, {\"site\": 68, \"_stat_site_order\": 67}, {\"site\": 69, \"_stat_site_order\": 68}, {\"site\": 70, \"_stat_site_order\": 69}, {\"site\": 71, \"_stat_site_order\": 70}, {\"site\": 72, \"_stat_site_order\": 71}, {\"site\": 73, \"_stat_site_order\": 72}, {\"site\": 74, \"_stat_site_order\": 73}, {\"site\": 75, \"_stat_site_order\": 74}, {\"site\": 76, \"_stat_site_order\": 75}, {\"site\": 77, \"_stat_site_order\": 76}, {\"site\": 78, \"_stat_site_order\": 77}, {\"site\": 79, \"_stat_site_order\": 78}, {\"site\": 80, \"_stat_site_order\": 79}, {\"site\": 81, \"_stat_site_order\": 80}, {\"site\": 82, \"_stat_site_order\": 81}, {\"site\": 83, \"_stat_site_order\": 82}, {\"site\": 84, \"_stat_site_order\": 83}, {\"site\": 85, \"_stat_site_order\": 84}, {\"site\": 86, \"_stat_site_order\": 85}, {\"site\": 87, \"_stat_site_order\": 86}, {\"site\": 88, \"_stat_site_order\": 87}, {\"site\": 89, \"_stat_site_order\": 88}, {\"site\": 90, \"_stat_site_order\": 89}, {\"site\": 91, \"_stat_site_order\": 90}, {\"site\": 92, \"_stat_site_order\": 91}, {\"site\": 93, \"_stat_site_order\": 92}, {\"site\": 94, \"_stat_site_order\": 93}, {\"site\": 95, \"_stat_site_order\": 94}, {\"site\": 96, \"_stat_site_order\": 95}, {\"site\": 97, \"_stat_site_order\": 96}, {\"site\": 98, \"_stat_site_order\": 97}, {\"site\": 99, \"_stat_site_order\": 98}, {\"site\": 100, \"_stat_site_order\": 99}, {\"site\": 101, \"_stat_site_order\": 100}, {\"site\": 102, \"_stat_site_order\": 101}, {\"site\": 103, \"_stat_site_order\": 102}, {\"site\": 104, \"_stat_site_order\": 103}, {\"site\": 105, \"_stat_site_order\": 104}, {\"site\": 106, \"_stat_site_order\": 105}, {\"site\": 107, \"_stat_site_order\": 106}, {\"site\": 108, \"_stat_site_order\": 107}, {\"site\": 109, \"_stat_site_order\": 108}, {\"site\": 110, \"_stat_site_order\": 109}, {\"site\": 111, \"_stat_site_order\": 110}, {\"site\": 112, \"_stat_site_order\": 111}, {\"site\": 113, \"_stat_site_order\": 112}, {\"site\": 114, \"_stat_site_order\": 113}, {\"site\": 115, \"_stat_site_order\": 114}, {\"site\": 116, \"_stat_site_order\": 115}, {\"site\": 117, \"_stat_site_order\": 116}, {\"site\": 118, \"_stat_site_order\": 117}, {\"site\": 119, \"_stat_site_order\": 118}, {\"site\": 120, \"_stat_site_order\": 119}, {\"site\": 121, \"_stat_site_order\": 120}, {\"site\": 122, \"_stat_site_order\": 121}, {\"site\": 123, \"_stat_site_order\": 122}, {\"site\": 124, \"_stat_site_order\": 123}, {\"site\": 125, \"_stat_site_order\": 124}, {\"site\": 126, \"_stat_site_order\": 125}, {\"site\": 127, \"_stat_site_order\": 126}, {\"site\": 128, \"_stat_site_order\": 127}, {\"site\": 129, \"_stat_site_order\": 128}, {\"site\": 130, \"_stat_site_order\": 129}, {\"site\": 131, \"_stat_site_order\": 130}, {\"site\": 132, \"_stat_site_order\": 131}, {\"site\": 133, \"_stat_site_order\": 132}, {\"site\": 134, \"_stat_site_order\": 133}, {\"site\": 135, \"_stat_site_order\": 134}, {\"site\": 136, \"_stat_site_order\": 135}, {\"site\": 137, \"_stat_site_order\": 136}, {\"site\": 138, \"_stat_site_order\": 137}, {\"site\": 139, \"_stat_site_order\": 138}, {\"site\": 140, \"_stat_site_order\": 139}, {\"site\": 141, \"_stat_site_order\": 140}, {\"site\": 142, \"_stat_site_order\": 141}, {\"site\": 143, \"_stat_site_order\": 142}, {\"site\": 144, \"_stat_site_order\": 143}, {\"site\": 145, \"_stat_site_order\": 144}, {\"site\": 146, \"_stat_site_order\": 145}, {\"site\": 147, \"_stat_site_order\": 146}, {\"site\": 148, \"_stat_site_order\": 147}, {\"site\": 149, \"_stat_site_order\": 148}, {\"site\": 150, \"_stat_site_order\": 149}, {\"site\": 151, \"_stat_site_order\": 150}, {\"site\": 152, \"_stat_site_order\": 151}, {\"site\": 153, \"_stat_site_order\": 152}, {\"site\": 154, \"_stat_site_order\": 153}, {\"site\": 155, \"_stat_site_order\": 154}, {\"site\": 156, \"_stat_site_order\": 155}, {\"site\": 157, \"_stat_site_order\": 156}, {\"site\": 158, \"_stat_site_order\": 157}, {\"site\": 159, \"_stat_site_order\": 158}, {\"site\": 160, \"_stat_site_order\": 159}, {\"site\": 161, \"_stat_site_order\": 160}, {\"site\": 162, \"_stat_site_order\": 161}, {\"site\": 163, \"_stat_site_order\": 162}, {\"site\": 164, \"_stat_site_order\": 163}, {\"site\": 165, \"_stat_site_order\": 164}, {\"site\": 166, \"_stat_site_order\": 165}, {\"site\": 167, \"_stat_site_order\": 166}, {\"site\": 168, \"_stat_site_order\": 167}, {\"site\": 169, \"_stat_site_order\": 168}, {\"site\": 170, \"_stat_site_order\": 169}, {\"site\": 171, \"_stat_site_order\": 170}, {\"site\": 172, \"_stat_site_order\": 171}, {\"site\": 173, \"_stat_site_order\": 172}, {\"site\": 174, \"_stat_site_order\": 173}, {\"site\": 175, \"_stat_site_order\": 174}, {\"site\": 176, \"_stat_site_order\": 175}, {\"site\": 177, \"_stat_site_order\": 176}, {\"site\": 178, \"_stat_site_order\": 177}, {\"site\": 179, \"_stat_site_order\": 178}, {\"site\": 180, \"_stat_site_order\": 179}, {\"site\": 181, \"_stat_site_order\": 180}, {\"site\": 182, \"_stat_site_order\": 181}, {\"site\": 183, \"_stat_site_order\": 182}, {\"site\": 184, \"_stat_site_order\": 183}, {\"site\": 185, \"_stat_site_order\": 184}, {\"site\": 186, \"_stat_site_order\": 185}, {\"site\": 187, \"_stat_site_order\": 186}, {\"site\": 188, \"_stat_site_order\": 187}, {\"site\": 189, \"_stat_site_order\": 188}, {\"site\": 190, \"_stat_site_order\": 189}, {\"site\": 191, \"_stat_site_order\": 190}, {\"site\": 192, \"_stat_site_order\": 191}, {\"site\": 193, \"_stat_site_order\": 192}, {\"site\": 194, \"_stat_site_order\": 193}, {\"site\": 195, \"_stat_site_order\": 194}, {\"site\": 196, \"_stat_site_order\": 195}, {\"site\": 197, \"_stat_site_order\": 196}, {\"site\": 198, \"_stat_site_order\": 197}, {\"site\": 199, \"_stat_site_order\": 198}, {\"site\": 200, \"_stat_site_order\": 199}, {\"site\": 201, \"_stat_site_order\": 200}, {\"site\": 202, \"_stat_site_order\": 201}, {\"site\": 203, \"_stat_site_order\": 202}, {\"site\": 204, \"_stat_site_order\": 203}, {\"site\": 205, \"_stat_site_order\": 204}, {\"site\": 206, \"_stat_site_order\": 205}, {\"site\": 207, \"_stat_site_order\": 206}, {\"site\": 208, \"_stat_site_order\": 207}, {\"site\": 209, \"_stat_site_order\": 208}, {\"site\": 210, \"_stat_site_order\": 209}, {\"site\": 211, \"_stat_site_order\": 210}, {\"site\": 212, \"_stat_site_order\": 211}, {\"site\": 213, \"_stat_site_order\": 212}, {\"site\": 214, \"_stat_site_order\": 213}, {\"site\": 215, \"_stat_site_order\": 214}, {\"site\": 216, \"_stat_site_order\": 215}, {\"site\": 217, \"_stat_site_order\": 216}, {\"site\": 218, \"_stat_site_order\": 217}, {\"site\": 219, \"_stat_site_order\": 218}, {\"site\": 220, \"_stat_site_order\": 219}, {\"site\": 221, \"_stat_site_order\": 220}, {\"site\": 222, \"_stat_site_order\": 221}, {\"site\": 223, \"_stat_site_order\": 222}, {\"site\": 224, \"_stat_site_order\": 223}, {\"site\": 225, \"_stat_site_order\": 224}, {\"site\": 226, \"_stat_site_order\": 225}, {\"site\": 227, \"_stat_site_order\": 226}, {\"site\": 228, \"_stat_site_order\": 227}, {\"site\": 229, \"_stat_site_order\": 228}, {\"site\": 230, \"_stat_site_order\": 229}, {\"site\": 231, \"_stat_site_order\": 230}, {\"site\": 232, \"_stat_site_order\": 231}, {\"site\": 233, \"_stat_site_order\": 232}, {\"site\": 234, \"_stat_site_order\": 233}, {\"site\": 235, \"_stat_site_order\": 234}, {\"site\": 236, \"_stat_site_order\": 235}, {\"site\": 237, \"_stat_site_order\": 236}, {\"site\": 238, \"_stat_site_order\": 237}, {\"site\": 239, \"_stat_site_order\": 238}, {\"site\": 240, \"_stat_site_order\": 239}, {\"site\": 241, \"_stat_site_order\": 240}, {\"site\": 242, \"_stat_site_order\": 241}, {\"site\": 243, \"_stat_site_order\": 242}, {\"site\": 244, \"_stat_site_order\": 243}, {\"site\": 245, \"_stat_site_order\": 244}, {\"site\": 246, \"_stat_site_order\": 245}, {\"site\": 247, \"_stat_site_order\": 246}, {\"site\": 248, \"_stat_site_order\": 247}, {\"site\": 249, \"_stat_site_order\": 248}, {\"site\": 250, \"_stat_site_order\": 249}, {\"site\": 251, \"_stat_site_order\": 250}, {\"site\": 252, \"_stat_site_order\": 251}, {\"site\": 253, \"_stat_site_order\": 252}, {\"site\": 254, \"_stat_site_order\": 253}, {\"site\": 255, \"_stat_site_order\": 254}, {\"site\": 256, \"_stat_site_order\": 255}, {\"site\": 257, \"_stat_site_order\": 256}, {\"site\": 258, \"_stat_site_order\": 257}, {\"site\": 259, \"_stat_site_order\": 258}, {\"site\": 260, \"_stat_site_order\": 259}, {\"site\": 261, \"_stat_site_order\": 260}, {\"site\": 262, \"_stat_site_order\": 261}, {\"site\": 263, \"_stat_site_order\": 262}, {\"site\": 264, \"_stat_site_order\": 263}, {\"site\": 265, \"_stat_site_order\": 264}, {\"site\": 266, \"_stat_site_order\": 265}, {\"site\": 267, \"_stat_site_order\": 266}, {\"site\": 268, \"_stat_site_order\": 267}, {\"site\": 269, \"_stat_site_order\": 268}, {\"site\": 270, \"_stat_site_order\": 269}, {\"site\": 271, \"_stat_site_order\": 270}, {\"site\": 272, \"_stat_site_order\": 271}, {\"site\": 273, \"_stat_site_order\": 272}, {\"site\": 274, \"_stat_site_order\": 273}, {\"site\": 275, \"_stat_site_order\": 274}, {\"site\": 276, \"_stat_site_order\": 275}, {\"site\": 277, \"_stat_site_order\": 276}, {\"site\": 278, \"_stat_site_order\": 277}, {\"site\": 279, \"_stat_site_order\": 278}, {\"site\": 280, \"_stat_site_order\": 279}, {\"site\": 281, \"_stat_site_order\": 280}, {\"site\": 282, \"_stat_site_order\": 281}, {\"site\": 283, \"_stat_site_order\": 282}, {\"site\": 284, \"_stat_site_order\": 283}, {\"site\": 285, \"_stat_site_order\": 284}, {\"site\": 286, \"_stat_site_order\": 285}, {\"site\": 287, \"_stat_site_order\": 286}, {\"site\": 288, \"_stat_site_order\": 287}, {\"site\": 289, \"_stat_site_order\": 288}, {\"site\": 290, \"_stat_site_order\": 289}, {\"site\": 291, \"_stat_site_order\": 290}, {\"site\": 292, \"_stat_site_order\": 291}, {\"site\": 293, \"_stat_site_order\": 292}, {\"site\": 294, \"_stat_site_order\": 293}, {\"site\": 295, \"_stat_site_order\": 294}, {\"site\": 296, \"_stat_site_order\": 295}, {\"site\": 297, \"_stat_site_order\": 296}, {\"site\": 298, \"_stat_site_order\": 297}, {\"site\": 299, \"_stat_site_order\": 298}, {\"site\": 300, \"_stat_site_order\": 299}, {\"site\": 301, \"_stat_site_order\": 300}, {\"site\": 302, \"_stat_site_order\": 301}, {\"site\": 303, \"_stat_site_order\": 302}, {\"site\": 304, \"_stat_site_order\": 303}, {\"site\": 305, \"_stat_site_order\": 304}, {\"site\": 306, \"_stat_site_order\": 305}, {\"site\": 307, \"_stat_site_order\": 306}, {\"site\": 308, \"_stat_site_order\": 307}, {\"site\": 309, \"_stat_site_order\": 308}, {\"site\": 310, \"_stat_site_order\": 309}, {\"site\": 311, \"_stat_site_order\": 310}, {\"site\": 312, \"_stat_site_order\": 311}, {\"site\": 313, \"_stat_site_order\": 312}, {\"site\": 314, \"_stat_site_order\": 313}, {\"site\": 315, \"_stat_site_order\": 314}, {\"site\": 316, \"_stat_site_order\": 315}, {\"site\": 317, \"_stat_site_order\": 316}, {\"site\": 318, \"_stat_site_order\": 317}, {\"site\": 319, \"_stat_site_order\": 318}, {\"site\": 320, \"_stat_site_order\": 319}, {\"site\": 321, \"_stat_site_order\": 320}, {\"site\": 322, \"_stat_site_order\": 321}, {\"site\": 323, \"_stat_site_order\": 322}, {\"site\": 324, \"_stat_site_order\": 323}, {\"site\": 325, \"_stat_site_order\": 324}, {\"site\": 326, \"_stat_site_order\": 325}, {\"site\": 327, \"_stat_site_order\": 326}, {\"site\": 328, \"_stat_site_order\": 327}, {\"site\": 329, \"_stat_site_order\": 328}, {\"site\": 330, \"_stat_site_order\": 329}, {\"site\": 331, \"_stat_site_order\": 330}, {\"site\": 332, \"_stat_site_order\": 331}, {\"site\": 333, \"_stat_site_order\": 332}, {\"site\": 334, \"_stat_site_order\": 333}, {\"site\": 335, \"_stat_site_order\": 334}, {\"site\": 336, \"_stat_site_order\": 335}, {\"site\": 337, \"_stat_site_order\": 336}, {\"site\": 338, \"_stat_site_order\": 337}, {\"site\": 339, \"_stat_site_order\": 338}, {\"site\": 340, \"_stat_site_order\": 339}, {\"site\": 341, \"_stat_site_order\": 340}, {\"site\": 342, \"_stat_site_order\": 341}, {\"site\": 343, \"_stat_site_order\": 342}, {\"site\": 345, \"_stat_site_order\": 343}, {\"site\": 346, \"_stat_site_order\": 344}, {\"site\": 347, \"_stat_site_order\": 345}, {\"site\": 348, \"_stat_site_order\": 346}, {\"site\": 349, \"_stat_site_order\": 347}, {\"site\": 350, \"_stat_site_order\": 348}, {\"site\": 351, \"_stat_site_order\": 349}, {\"site\": 352, \"_stat_site_order\": 350}, {\"site\": 353, \"_stat_site_order\": 351}, {\"site\": 354, \"_stat_site_order\": 352}, {\"site\": 355, \"_stat_site_order\": 353}, {\"site\": 356, \"_stat_site_order\": 354}, {\"site\": 357, \"_stat_site_order\": 355}, {\"site\": 358, \"_stat_site_order\": 356}, {\"site\": 359, \"_stat_site_order\": 357}, {\"site\": 360, \"_stat_site_order\": 358}, {\"site\": 361, \"_stat_site_order\": 359}, {\"site\": 362, \"_stat_site_order\": 360}, {\"site\": 363, \"_stat_site_order\": 361}, {\"site\": 364, \"_stat_site_order\": 362}, {\"site\": 365, \"_stat_site_order\": 363}, {\"site\": 366, \"_stat_site_order\": 364}, {\"site\": 367, \"_stat_site_order\": 365}, {\"site\": 368, \"_stat_site_order\": 366}, {\"site\": 369, \"_stat_site_order\": 367}, {\"site\": 370, \"_stat_site_order\": 368}, {\"site\": 371, \"_stat_site_order\": 369}, {\"site\": 372, \"_stat_site_order\": 370}, {\"site\": 373, \"_stat_site_order\": 371}, {\"site\": 374, \"_stat_site_order\": 372}, {\"site\": 375, \"_stat_site_order\": 373}, {\"site\": 376, \"_stat_site_order\": 374}, {\"site\": 377, \"_stat_site_order\": 375}, {\"site\": 378, \"_stat_site_order\": 376}, {\"site\": 379, \"_stat_site_order\": 377}, {\"site\": 380, \"_stat_site_order\": 378}, {\"site\": 381, \"_stat_site_order\": 379}, {\"site\": 382, \"_stat_site_order\": 380}, {\"site\": 383, \"_stat_site_order\": 381}, {\"site\": 384, \"_stat_site_order\": 382}, {\"site\": 385, \"_stat_site_order\": 383}, {\"site\": 386, \"_stat_site_order\": 384}, {\"site\": 387, \"_stat_site_order\": 385}, {\"site\": 388, \"_stat_site_order\": 386}, {\"site\": 389, \"_stat_site_order\": 387}, {\"site\": 390, \"_stat_site_order\": 388}, {\"site\": 391, \"_stat_site_order\": 389}, {\"site\": 392, \"_stat_site_order\": 390}, {\"site\": 393, \"_stat_site_order\": 391}, {\"site\": 394, \"_stat_site_order\": 392}, {\"site\": 395, \"_stat_site_order\": 393}, {\"site\": 396, \"_stat_site_order\": 394}, {\"site\": 397, \"_stat_site_order\": 395}, {\"site\": 398, \"_stat_site_order\": 396}, {\"site\": 399, \"_stat_site_order\": 397}, {\"site\": 400, \"_stat_site_order\": 398}, {\"site\": 401, \"_stat_site_order\": 399}, {\"site\": 402, \"_stat_site_order\": 400}, {\"site\": 403, \"_stat_site_order\": 401}, {\"site\": 404, \"_stat_site_order\": 402}, {\"site\": 405, \"_stat_site_order\": 403}, {\"site\": 406, \"_stat_site_order\": 404}, {\"site\": 407, \"_stat_site_order\": 405}, {\"site\": 408, \"_stat_site_order\": 406}, {\"site\": 409, \"_stat_site_order\": 407}, {\"site\": 410, \"_stat_site_order\": 408}, {\"site\": 411, \"_stat_site_order\": 409}, {\"site\": 412, \"_stat_site_order\": 410}, {\"site\": 413, \"_stat_site_order\": 411}, {\"site\": 414, \"_stat_site_order\": 412}, {\"site\": 415, \"_stat_site_order\": 413}, {\"site\": 416, \"_stat_site_order\": 414}, {\"site\": 417, \"_stat_site_order\": 415}, {\"site\": 418, \"_stat_site_order\": 416}, {\"site\": 419, \"_stat_site_order\": 417}, {\"site\": 420, \"_stat_site_order\": 418}, {\"site\": 421, \"_stat_site_order\": 419}, {\"site\": 422, \"_stat_site_order\": 420}, {\"site\": 423, \"_stat_site_order\": 421}, {\"site\": 424, \"_stat_site_order\": 422}, {\"site\": 425, \"_stat_site_order\": 423}, {\"site\": 426, \"_stat_site_order\": 424}, {\"site\": 427, \"_stat_site_order\": 425}, {\"site\": 428, \"_stat_site_order\": 426}, {\"site\": 429, \"_stat_site_order\": 427}, {\"site\": 430, \"_stat_site_order\": 428}, {\"site\": 431, \"_stat_site_order\": 429}, {\"site\": 432, \"_stat_site_order\": 430}, {\"site\": 433, \"_stat_site_order\": 431}, {\"site\": 434, \"_stat_site_order\": 432}, {\"site\": 435, \"_stat_site_order\": 433}, {\"site\": 436, \"_stat_site_order\": 434}, {\"site\": 437, \"_stat_site_order\": 435}, {\"site\": 438, \"_stat_site_order\": 436}, {\"site\": 439, \"_stat_site_order\": 437}, {\"site\": 440, \"_stat_site_order\": 438}, {\"site\": 441, \"_stat_site_order\": 439}, {\"site\": 442, \"_stat_site_order\": 440}, {\"site\": 443, \"_stat_site_order\": 441}, {\"site\": 444, \"_stat_site_order\": 442}, {\"site\": 445, \"_stat_site_order\": 443}, {\"site\": 446, \"_stat_site_order\": 444}, {\"site\": 447, \"_stat_site_order\": 445}, {\"site\": 448, \"_stat_site_order\": 446}, {\"site\": 449, \"_stat_site_order\": 447}, {\"site\": 450, \"_stat_site_order\": 448}, {\"site\": 451, \"_stat_site_order\": 449}, {\"site\": 452, \"_stat_site_order\": 450}, {\"site\": 453, \"_stat_site_order\": 451}, {\"site\": 454, \"_stat_site_order\": 452}, {\"site\": 455, \"_stat_site_order\": 453}, {\"site\": 456, \"_stat_site_order\": 454}, {\"site\": 457, \"_stat_site_order\": 455}, {\"site\": 458, \"_stat_site_order\": 456}, {\"site\": 459, \"_stat_site_order\": 457}, {\"site\": 460, \"_stat_site_order\": 458}, {\"site\": 461, \"_stat_site_order\": 459}, {\"site\": 462, \"_stat_site_order\": 460}, {\"site\": 463, \"_stat_site_order\": 461}, {\"site\": 464, \"_stat_site_order\": 462}, {\"site\": 465, \"_stat_site_order\": 463}, {\"site\": 466, \"_stat_site_order\": 464}, {\"site\": 467, \"_stat_site_order\": 465}, {\"site\": 468, \"_stat_site_order\": 466}, {\"site\": 469, \"_stat_site_order\": 467}, {\"site\": 470, \"_stat_site_order\": 468}, {\"site\": 471, \"_stat_site_order\": 469}, {\"site\": 472, \"_stat_site_order\": 470}, {\"site\": 473, \"_stat_site_order\": 471}, {\"site\": 474, \"_stat_site_order\": 472}, {\"site\": 475, \"_stat_site_order\": 473}, {\"site\": 476, \"_stat_site_order\": 474}, {\"site\": 477, \"_stat_site_order\": 475}, {\"site\": 478, \"_stat_site_order\": 476}, {\"site\": 479, \"_stat_site_order\": 477}, {\"site\": 480, \"_stat_site_order\": 478}, {\"site\": 481, \"_stat_site_order\": 479}, {\"site\": 482, \"_stat_site_order\": 480}, {\"site\": 483, \"_stat_site_order\": 481}, {\"site\": 484, \"_stat_site_order\": 482}, {\"site\": 485, \"_stat_site_order\": 483}, {\"site\": 486, \"_stat_site_order\": 484}, {\"site\": 487, \"_stat_site_order\": 485}, {\"site\": 488, \"_stat_site_order\": 486}, {\"site\": 489, \"_stat_site_order\": 487}, {\"site\": 490, \"_stat_site_order\": 488}, {\"site\": 491, \"_stat_site_order\": 489}, {\"site\": 492, \"_stat_site_order\": 490}, {\"site\": 493, \"_stat_site_order\": 491}, {\"site\": 494, \"_stat_site_order\": 492}, {\"site\": 495, \"_stat_site_order\": 493}, {\"site\": 496, \"_stat_site_order\": 494}, {\"site\": 497, \"_stat_site_order\": 495}, {\"site\": 498, \"_stat_site_order\": 496}, {\"site\": 499, \"_stat_site_order\": 497}, {\"site\": 500, \"_stat_site_order\": 498}, {\"site\": 501, \"_stat_site_order\": 499}, {\"site\": 502, \"_stat_site_order\": 500}, {\"site\": 503, \"_stat_site_order\": 501}, {\"site\": 504, \"_stat_site_order\": 502}, {\"site\": 505, \"_stat_site_order\": 503}, {\"site\": 506, \"_stat_site_order\": 504}, {\"site\": 507, \"_stat_site_order\": 505}, {\"site\": 508, \"_stat_site_order\": 506}, {\"site\": 509, \"_stat_site_order\": 507}, {\"site\": 510, \"_stat_site_order\": 508}, {\"site\": 511, \"_stat_site_order\": 509}, {\"site\": 512, \"_stat_site_order\": 510}, {\"site\": 513, \"_stat_site_order\": 511}, {\"site\": 514, \"_stat_site_order\": 512}, {\"site\": 515, \"_stat_site_order\": 513}, {\"site\": 516, \"_stat_site_order\": 514}, {\"site\": 517, \"_stat_site_order\": 515}, {\"site\": 518, \"_stat_site_order\": 516}, {\"site\": 519, \"_stat_site_order\": 517}, {\"site\": 520, \"_stat_site_order\": 518}, {\"site\": 521, \"_stat_site_order\": 519}, {\"site\": 522, \"_stat_site_order\": 520}, {\"site\": 523, \"_stat_site_order\": 521}, {\"site\": 524, \"_stat_site_order\": 522}, {\"site\": 525, \"_stat_site_order\": 523}, {\"site\": 526, \"_stat_site_order\": 524}, {\"site\": 527, \"_stat_site_order\": 525}, {\"site\": 528, \"_stat_site_order\": 526}, {\"site\": 529, \"_stat_site_order\": 527}, {\"site\": 530, \"_stat_site_order\": 528}, {\"site\": 531, \"_stat_site_order\": 529}, {\"site\": 532, \"_stat_site_order\": 530}, {\"site\": 533, \"_stat_site_order\": 531}, {\"site\": 534, \"_stat_site_order\": 532}, {\"site\": 535, \"_stat_site_order\": 533}, {\"site\": 536, \"_stat_site_order\": 534}, {\"site\": 537, \"_stat_site_order\": 535}, {\"site\": 538, \"_stat_site_order\": 536}, {\"site\": 539, \"_stat_site_order\": 537}, {\"site\": 540, \"_stat_site_order\": 538}, {\"site\": 541, \"_stat_site_order\": 539}, {\"site\": 542, \"_stat_site_order\": 540}, {\"site\": 543, \"_stat_site_order\": 541}, {\"site\": 544, \"_stat_site_order\": 542}, {\"site\": 545, \"_stat_site_order\": 543}, {\"site\": 546, \"_stat_site_order\": 544}, {\"site\": 547, \"_stat_site_order\": 545}, {\"site\": 548, \"_stat_site_order\": 546}, {\"site\": 549, \"_stat_site_order\": 547}, {\"site\": 550, \"_stat_site_order\": 548}, {\"site\": 551, \"_stat_site_order\": 549}, {\"site\": 552, \"_stat_site_order\": 550}, {\"site\": 553, \"_stat_site_order\": 551}, {\"site\": 554, \"_stat_site_order\": 552}, {\"site\": 555, \"_stat_site_order\": 553}, {\"site\": 556, \"_stat_site_order\": 554}, {\"site\": 557, \"_stat_site_order\": 555}, {\"site\": 558, \"_stat_site_order\": 556}, {\"site\": 559, \"_stat_site_order\": 557}, {\"site\": 560, \"_stat_site_order\": 558}, {\"site\": 561, \"_stat_site_order\": 559}, {\"site\": 562, \"_stat_site_order\": 560}, {\"site\": 563, \"_stat_site_order\": 561}, {\"site\": 564, \"_stat_site_order\": 562}, {\"site\": 565, \"_stat_site_order\": 563}, {\"site\": 566, \"_stat_site_order\": 564}, {\"site\": 567, \"_stat_site_order\": 565}, {\"site\": 568, \"_stat_site_order\": 566}, {\"site\": 569, \"_stat_site_order\": 567}, {\"site\": 570, \"_stat_site_order\": 568}, {\"site\": 571, \"_stat_site_order\": 569}, {\"site\": 572, \"_stat_site_order\": 570}, {\"site\": 573, \"_stat_site_order\": 571}, {\"site\": 574, \"_stat_site_order\": 572}, {\"site\": 575, \"_stat_site_order\": 573}, {\"site\": 576, \"_stat_site_order\": 574}, {\"site\": 577, \"_stat_site_order\": 575}, {\"site\": 578, \"_stat_site_order\": 576}, {\"site\": 579, \"_stat_site_order\": 577}, {\"site\": 580, \"_stat_site_order\": 578}, {\"site\": 581, \"_stat_site_order\": 579}, {\"site\": 582, \"_stat_site_order\": 580}, {\"site\": 583, \"_stat_site_order\": 581}, {\"site\": 584, \"_stat_site_order\": 582}, {\"site\": 585, \"_stat_site_order\": 583}, {\"site\": 586, \"_stat_site_order\": 584}, {\"site\": 587, \"_stat_site_order\": 585}, {\"site\": 588, \"_stat_site_order\": 586}, {\"site\": 589, \"_stat_site_order\": 587}, {\"site\": 590, \"_stat_site_order\": 588}, {\"site\": 591, \"_stat_site_order\": 589}, {\"site\": 592, \"_stat_site_order\": 590}, {\"site\": 593, \"_stat_site_order\": 591}, {\"site\": 594, \"_stat_site_order\": 592}, {\"site\": 595, \"_stat_site_order\": 593}, {\"site\": 596, \"_stat_site_order\": 594}, {\"site\": 597, \"_stat_site_order\": 595}, {\"site\": 598, \"_stat_site_order\": 596}, {\"site\": 599, \"_stat_site_order\": 597}, {\"site\": 600, \"_stat_site_order\": 598}, {\"site\": 601, \"_stat_site_order\": 599}, {\"site\": 602, \"_stat_site_order\": 600}, {\"site\": 603, \"_stat_site_order\": 601}, {\"site\": 604, \"_stat_site_order\": 602}, {\"site\": 605, \"_stat_site_order\": 603}, {\"site\": 606, \"_stat_site_order\": 604}, {\"site\": 607, \"_stat_site_order\": 605}, {\"site\": 608, \"_stat_site_order\": 606}, {\"site\": 609, \"_stat_site_order\": 607}, {\"site\": 610, \"_stat_site_order\": 608}, {\"site\": 611, \"_stat_site_order\": 609}, {\"site\": 612, \"_stat_site_order\": 610}, {\"site\": 613, \"_stat_site_order\": 611}, {\"site\": 614, \"_stat_site_order\": 612}, {\"site\": 615, \"_stat_site_order\": 613}, {\"site\": 616, \"_stat_site_order\": 614}, {\"site\": 617, \"_stat_site_order\": 615}, {\"site\": 618, \"_stat_site_order\": 616}, {\"site\": 619, \"_stat_site_order\": 617}, {\"site\": 620, \"_stat_site_order\": 618}, {\"site\": 621, \"_stat_site_order\": 619}, {\"site\": 622, \"_stat_site_order\": 620}, {\"site\": 623, \"_stat_site_order\": 621}, {\"site\": 624, \"_stat_site_order\": 622}, {\"site\": 625, \"_stat_site_order\": 623}, {\"site\": 626, \"_stat_site_order\": 624}, {\"site\": 627, \"_stat_site_order\": 625}, {\"site\": 628, \"_stat_site_order\": 626}, {\"site\": 629, \"_stat_site_order\": 627}, {\"site\": 630, \"_stat_site_order\": 628}, {\"site\": 631, \"_stat_site_order\": 629}, {\"site\": 632, \"_stat_site_order\": 630}, {\"site\": 633, \"_stat_site_order\": 631}, {\"site\": 634, \"_stat_site_order\": 632}, {\"site\": 635, \"_stat_site_order\": 633}, {\"site\": 636, \"_stat_site_order\": 634}, {\"site\": 637, \"_stat_site_order\": 635}, {\"site\": 638, \"_stat_site_order\": 636}, {\"site\": 639, \"_stat_site_order\": 637}, {\"site\": 640, \"_stat_site_order\": 638}, {\"site\": 641, \"_stat_site_order\": 639}, {\"site\": 642, \"_stat_site_order\": 640}, {\"site\": 643, \"_stat_site_order\": 641}, {\"site\": 644, \"_stat_site_order\": 642}, {\"site\": 645, \"_stat_site_order\": 643}, {\"site\": 646, \"_stat_site_order\": 644}, {\"site\": 647, \"_stat_site_order\": 645}, {\"site\": 648, \"_stat_site_order\": 646}, {\"site\": 649, \"_stat_site_order\": 647}, {\"site\": 650, \"_stat_site_order\": 648}, {\"site\": 651, \"_stat_site_order\": 649}, {\"site\": 652, \"_stat_site_order\": 650}, {\"site\": 653, \"_stat_site_order\": 651}, {\"site\": 654, \"_stat_site_order\": 652}, {\"site\": 655, \"_stat_site_order\": 653}, {\"site\": 656, \"_stat_site_order\": 654}, {\"site\": 657, \"_stat_site_order\": 655}, {\"site\": 658, \"_stat_site_order\": 656}, {\"site\": 659, \"_stat_site_order\": 657}, {\"site\": 660, \"_stat_site_order\": 658}, {\"site\": 661, \"_stat_site_order\": 659}, {\"site\": 662, \"_stat_site_order\": 660}, {\"site\": 663, \"_stat_site_order\": 661}, {\"site\": 664, \"_stat_site_order\": 662}, {\"site\": 665, \"_stat_site_order\": 663}, {\"site\": 666, \"_stat_site_order\": 664}, {\"site\": 667, \"_stat_site_order\": 665}, {\"site\": 668, \"_stat_site_order\": 666}, {\"site\": 669, \"_stat_site_order\": 667}, {\"site\": 670, \"_stat_site_order\": 668}, {\"site\": 671, \"_stat_site_order\": 669}, {\"site\": 672, \"_stat_site_order\": 670}, {\"site\": 673, \"_stat_site_order\": 671}, {\"site\": 674, \"_stat_site_order\": 672}, {\"site\": 675, \"_stat_site_order\": 673}, {\"site\": 676, \"_stat_site_order\": 674}, {\"site\": 677, \"_stat_site_order\": 675}, {\"site\": 678, \"_stat_site_order\": 676}, {\"site\": 679, \"_stat_site_order\": 677}, {\"site\": 680, \"_stat_site_order\": 678}, {\"site\": 681, \"_stat_site_order\": 679}, {\"site\": 682, \"_stat_site_order\": 680}, {\"site\": 683, \"_stat_site_order\": 681}, {\"site\": 684, \"_stat_site_order\": 682}, {\"site\": 685, \"_stat_site_order\": 683}, {\"site\": 686, \"_stat_site_order\": 684}, {\"site\": 687, \"_stat_site_order\": 685}, {\"site\": 688, \"_stat_site_order\": 686}, {\"site\": 689, \"_stat_site_order\": 687}, {\"site\": 690, \"_stat_site_order\": 688}, {\"site\": 691, \"_stat_site_order\": 689}, {\"site\": 693, \"_stat_site_order\": 690}, {\"site\": 694, \"_stat_site_order\": 691}, {\"site\": 695, \"_stat_site_order\": 692}, {\"site\": 696, \"_stat_site_order\": 693}, {\"site\": 697, \"_stat_site_order\": 694}, {\"site\": 698, \"_stat_site_order\": 695}, {\"site\": 699, \"_stat_site_order\": 696}, {\"site\": 700, \"_stat_site_order\": 697}, {\"site\": 701, \"_stat_site_order\": 698}, {\"site\": 702, \"_stat_site_order\": 699}, {\"site\": 703, \"_stat_site_order\": 700}, {\"site\": 704, \"_stat_site_order\": 701}, {\"site\": 705, \"_stat_site_order\": 702}, {\"site\": 706, \"_stat_site_order\": 703}, {\"site\": 707, \"_stat_site_order\": 704}, {\"site\": 708, \"_stat_site_order\": 705}, {\"site\": 709, \"_stat_site_order\": 706}, {\"site\": 710, \"_stat_site_order\": 707}, {\"site\": 711, \"_stat_site_order\": 708}, {\"site\": 712, \"_stat_site_order\": 709}, {\"site\": 713, \"_stat_site_order\": 710}, {\"site\": 714, \"_stat_site_order\": 711}, {\"site\": 715, \"_stat_site_order\": 712}, {\"site\": 716, \"_stat_site_order\": 713}, {\"site\": 717, \"_stat_site_order\": 714}, {\"site\": 718, \"_stat_site_order\": 715}, {\"site\": 719, \"_stat_site_order\": 716}, {\"site\": 720, \"_stat_site_order\": 717}, {\"site\": 721, \"_stat_site_order\": 718}, {\"site\": 722, \"_stat_site_order\": 719}, {\"site\": 723, \"_stat_site_order\": 720}, {\"site\": 724, \"_stat_site_order\": 721}, {\"site\": 725, \"_stat_site_order\": 722}, {\"site\": 726, \"_stat_site_order\": 723}, {\"site\": 727, \"_stat_site_order\": 724}, {\"site\": 728, \"_stat_site_order\": 725}, {\"site\": 729, \"_stat_site_order\": 726}, {\"site\": 730, \"_stat_site_order\": 727}, {\"site\": 731, \"_stat_site_order\": 728}, {\"site\": 732, \"_stat_site_order\": 729}, {\"site\": 733, \"_stat_site_order\": 730}, {\"site\": 734, \"_stat_site_order\": 731}, {\"site\": 735, \"_stat_site_order\": 732}, {\"site\": 736, \"_stat_site_order\": 733}, {\"site\": 737, \"_stat_site_order\": 734}, {\"site\": 738, \"_stat_site_order\": 735}, {\"site\": 739, \"_stat_site_order\": 736}, {\"site\": 740, \"_stat_site_order\": 737}, {\"site\": 741, \"_stat_site_order\": 738}, {\"site\": 742, \"_stat_site_order\": 739}, {\"site\": 743, \"_stat_site_order\": 740}, {\"site\": 744, \"_stat_site_order\": 741}, {\"site\": 745, \"_stat_site_order\": 742}, {\"site\": 746, \"_stat_site_order\": 743}, {\"site\": 747, \"_stat_site_order\": 744}, {\"site\": 748, \"_stat_site_order\": 745}, {\"site\": 749, \"_stat_site_order\": 746}, {\"site\": 750, \"_stat_site_order\": 747}, {\"site\": 751, \"_stat_site_order\": 748}, {\"site\": 752, \"_stat_site_order\": 749}, {\"site\": 753, \"_stat_site_order\": 750}, {\"site\": 754, \"_stat_site_order\": 751}, {\"site\": 755, \"_stat_site_order\": 752}, {\"site\": 756, \"_stat_site_order\": 753}, {\"site\": 757, \"_stat_site_order\": 754}, {\"site\": 758, \"_stat_site_order\": 755}, {\"site\": 759, \"_stat_site_order\": 756}, {\"site\": 760, \"_stat_site_order\": 757}, {\"site\": 761, \"_stat_site_order\": 758}, {\"site\": 762, \"_stat_site_order\": 759}, {\"site\": 763, \"_stat_site_order\": 760}, {\"site\": 764, \"_stat_site_order\": 761}, {\"site\": 765, \"_stat_site_order\": 762}, {\"site\": 766, \"_stat_site_order\": 763}, {\"site\": 767, \"_stat_site_order\": 764}, {\"site\": 768, \"_stat_site_order\": 765}, {\"site\": 769, \"_stat_site_order\": 766}, {\"site\": 770, \"_stat_site_order\": 767}, {\"site\": 771, \"_stat_site_order\": 768}, {\"site\": 772, \"_stat_site_order\": 769}, {\"site\": 773, \"_stat_site_order\": 770}, {\"site\": 774, \"_stat_site_order\": 771}, {\"site\": 775, \"_stat_site_order\": 772}, {\"site\": 776, \"_stat_site_order\": 773}, {\"site\": 777, \"_stat_site_order\": 774}, {\"site\": 778, \"_stat_site_order\": 775}, {\"site\": 779, \"_stat_site_order\": 776}, {\"site\": 780, \"_stat_site_order\": 777}, {\"site\": 781, \"_stat_site_order\": 778}, {\"site\": 782, \"_stat_site_order\": 779}, {\"site\": 783, \"_stat_site_order\": 780}, {\"site\": 784, \"_stat_site_order\": 781}, {\"site\": 785, \"_stat_site_order\": 782}, {\"site\": 786, \"_stat_site_order\": 783}, {\"site\": 787, \"_stat_site_order\": 784}, {\"site\": 788, \"_stat_site_order\": 785}, {\"site\": 789, \"_stat_site_order\": 786}, {\"site\": 790, \"_stat_site_order\": 787}, {\"site\": 791, \"_stat_site_order\": 788}, {\"site\": 792, \"_stat_site_order\": 789}, {\"site\": 793, \"_stat_site_order\": 790}, {\"site\": 794, \"_stat_site_order\": 791}, {\"site\": 795, \"_stat_site_order\": 792}, {\"site\": 796, \"_stat_site_order\": 793}, {\"site\": 797, \"_stat_site_order\": 794}, {\"site\": 798, \"_stat_site_order\": 795}, {\"site\": 799, \"_stat_site_order\": 796}, {\"site\": 800, \"_stat_site_order\": 797}, {\"site\": 801, \"_stat_site_order\": 798}, {\"site\": 802, \"_stat_site_order\": 799}, {\"site\": 803, \"_stat_site_order\": 800}, {\"site\": 804, \"_stat_site_order\": 801}, {\"site\": 805, \"_stat_site_order\": 802}, {\"site\": 806, \"_stat_site_order\": 803}, {\"site\": 807, \"_stat_site_order\": 804}, {\"site\": 808, \"_stat_site_order\": 805}, {\"site\": 809, \"_stat_site_order\": 806}, {\"site\": 810, \"_stat_site_order\": 807}, {\"site\": 811, \"_stat_site_order\": 808}, {\"site\": 812, \"_stat_site_order\": 809}, {\"site\": 813, \"_stat_site_order\": 810}, {\"site\": 814, \"_stat_site_order\": 811}, {\"site\": 815, \"_stat_site_order\": 812}, {\"site\": 816, \"_stat_site_order\": 813}, {\"site\": 817, \"_stat_site_order\": 814}, {\"site\": 818, \"_stat_site_order\": 815}, {\"site\": 819, \"_stat_site_order\": 816}, {\"site\": 820, \"_stat_site_order\": 817}, {\"site\": 821, \"_stat_site_order\": 818}, {\"site\": 822, \"_stat_site_order\": 819}, {\"site\": 823, \"_stat_site_order\": 820}, {\"site\": 824, \"_stat_site_order\": 821}, {\"site\": 825, \"_stat_site_order\": 822}, {\"site\": 826, \"_stat_site_order\": 823}, {\"site\": 827, \"_stat_site_order\": 824}, {\"site\": 828, \"_stat_site_order\": 825}, {\"site\": 829, \"_stat_site_order\": 826}, {\"site\": 830, \"_stat_site_order\": 827}, {\"site\": 831, \"_stat_site_order\": 828}, {\"site\": 832, \"_stat_site_order\": 829}, {\"site\": 833, \"_stat_site_order\": 830}, {\"site\": 834, \"_stat_site_order\": 831}, {\"site\": 835, \"_stat_site_order\": 832}, {\"site\": 836, \"_stat_site_order\": 833}, {\"site\": 837, \"_stat_site_order\": 834}, {\"site\": 838, \"_stat_site_order\": 835}, {\"site\": 839, \"_stat_site_order\": 836}, {\"site\": 840, \"_stat_site_order\": 837}, {\"site\": 841, \"_stat_site_order\": 838}, {\"site\": 842, \"_stat_site_order\": 839}, {\"site\": 843, \"_stat_site_order\": 840}, {\"site\": 844, \"_stat_site_order\": 841}, {\"site\": 845, \"_stat_site_order\": 842}, {\"site\": 846, \"_stat_site_order\": 843}, {\"site\": 847, \"_stat_site_order\": 844}, {\"site\": 848, \"_stat_site_order\": 845}, {\"site\": 849, \"_stat_site_order\": 846}, {\"site\": 850, \"_stat_site_order\": 847}, {\"site\": 851, \"_stat_site_order\": 848}, {\"site\": 852, \"_stat_site_order\": 849}, {\"site\": 853, \"_stat_site_order\": 850}, {\"site\": 854, \"_stat_site_order\": 851}, {\"site\": 855, \"_stat_site_order\": 852}, {\"site\": 856, \"_stat_site_order\": 853}, {\"site\": 857, \"_stat_site_order\": 854}, {\"site\": 858, \"_stat_site_order\": 855}, {\"site\": 859, \"_stat_site_order\": 856}, {\"site\": 860, \"_stat_site_order\": 857}, {\"site\": 861, \"_stat_site_order\": 858}, {\"site\": 862, \"_stat_site_order\": 859}, {\"site\": 863, \"_stat_site_order\": 860}, {\"site\": 864, \"_stat_site_order\": 861}, {\"site\": 865, \"_stat_site_order\": 862}, {\"site\": 866, \"_stat_site_order\": 863}, {\"site\": 867, \"_stat_site_order\": 864}, {\"site\": 868, \"_stat_site_order\": 865}, {\"site\": 869, \"_stat_site_order\": 866}, {\"site\": 870, \"_stat_site_order\": 867}, {\"site\": 871, \"_stat_site_order\": 868}, {\"site\": 872, \"_stat_site_order\": 869}, {\"site\": 873, \"_stat_site_order\": 870}, {\"site\": 874, \"_stat_site_order\": 871}, {\"site\": 875, \"_stat_site_order\": 872}, {\"site\": 876, \"_stat_site_order\": 873}, {\"site\": 877, \"_stat_site_order\": 874}, {\"site\": 878, \"_stat_site_order\": 875}, {\"site\": 879, \"_stat_site_order\": 876}, {\"site\": 880, \"_stat_site_order\": 877}, {\"site\": 881, \"_stat_site_order\": 878}, {\"site\": 882, \"_stat_site_order\": 879}, {\"site\": 883, \"_stat_site_order\": 880}, {\"site\": 884, \"_stat_site_order\": 881}, {\"site\": 885, \"_stat_site_order\": 882}, {\"site\": 886, \"_stat_site_order\": 883}, {\"site\": 887, \"_stat_site_order\": 884}, {\"site\": 888, \"_stat_site_order\": 885}, {\"site\": 889, \"_stat_site_order\": 886}, {\"site\": 890, \"_stat_site_order\": 887}, {\"site\": 891, \"_stat_site_order\": 888}, {\"site\": 892, \"_stat_site_order\": 889}, {\"site\": 893, \"_stat_site_order\": 890}, {\"site\": 894, \"_stat_site_order\": 891}, {\"site\": 895, \"_stat_site_order\": 892}, {\"site\": 896, \"_stat_site_order\": 893}, {\"site\": 897, \"_stat_site_order\": 894}, {\"site\": 898, \"_stat_site_order\": 895}, {\"site\": 899, \"_stat_site_order\": 896}, {\"site\": 900, \"_stat_site_order\": 897}, {\"site\": 901, \"_stat_site_order\": 898}, {\"site\": 902, \"_stat_site_order\": 899}, {\"site\": 903, \"_stat_site_order\": 900}, {\"site\": 904, \"_stat_site_order\": 901}, {\"site\": 905, \"_stat_site_order\": 902}, {\"site\": 906, \"_stat_site_order\": 903}, {\"site\": 907, \"_stat_site_order\": 904}, {\"site\": 908, \"_stat_site_order\": 905}, {\"site\": 909, \"_stat_site_order\": 906}, {\"site\": 910, \"_stat_site_order\": 907}, {\"site\": 911, \"_stat_site_order\": 908}, {\"site\": 912, \"_stat_site_order\": 909}, {\"site\": 913, \"_stat_site_order\": 910}, {\"site\": 914, \"_stat_site_order\": 911}, {\"site\": 915, \"_stat_site_order\": 912}, {\"site\": 916, \"_stat_site_order\": 913}, {\"site\": 917, \"_stat_site_order\": 914}, {\"site\": 918, \"_stat_site_order\": 915}, {\"site\": 919, \"_stat_site_order\": 916}, {\"site\": 920, \"_stat_site_order\": 917}, {\"site\": 921, \"_stat_site_order\": 918}, {\"site\": 922, \"_stat_site_order\": 919}, {\"site\": 923, \"_stat_site_order\": 920}, {\"site\": 924, \"_stat_site_order\": 921}, {\"site\": 925, \"_stat_site_order\": 922}, {\"site\": 926, \"_stat_site_order\": 923}, {\"site\": 927, \"_stat_site_order\": 924}, {\"site\": 928, \"_stat_site_order\": 925}, {\"site\": 929, \"_stat_site_order\": 926}, {\"site\": 930, \"_stat_site_order\": 927}, {\"site\": 931, \"_stat_site_order\": 928}, {\"site\": 932, \"_stat_site_order\": 929}, {\"site\": 933, \"_stat_site_order\": 930}, {\"site\": 934, \"_stat_site_order\": 931}, {\"site\": 935, \"_stat_site_order\": 932}, {\"site\": 936, \"_stat_site_order\": 933}, {\"site\": 937, \"_stat_site_order\": 934}, {\"site\": 938, \"_stat_site_order\": 935}, {\"site\": 939, \"_stat_site_order\": 936}, {\"site\": 940, \"_stat_site_order\": 937}, {\"site\": 941, \"_stat_site_order\": 938}, {\"site\": 942, \"_stat_site_order\": 939}, {\"site\": 943, \"_stat_site_order\": 940}, {\"site\": 944, \"_stat_site_order\": 941}, {\"site\": 945, \"_stat_site_order\": 942}, {\"site\": 946, \"_stat_site_order\": 943}, {\"site\": 947, \"_stat_site_order\": 944}, {\"site\": 948, \"_stat_site_order\": 945}, {\"site\": 949, \"_stat_site_order\": 946}, {\"site\": 950, \"_stat_site_order\": 947}, {\"site\": 951, \"_stat_site_order\": 948}, {\"site\": 952, \"_stat_site_order\": 949}, {\"site\": 953, \"_stat_site_order\": 950}, {\"site\": 954, \"_stat_site_order\": 951}, {\"site\": 955, \"_stat_site_order\": 952}, {\"site\": 956, \"_stat_site_order\": 953}, {\"site\": 957, \"_stat_site_order\": 954}, {\"site\": 958, \"_stat_site_order\": 955}, {\"site\": 959, \"_stat_site_order\": 956}, {\"site\": 960, \"_stat_site_order\": 957}, {\"site\": 961, \"_stat_site_order\": 958}, {\"site\": 962, \"_stat_site_order\": 959}, {\"site\": 963, \"_stat_site_order\": 960}, {\"site\": 964, \"_stat_site_order\": 961}, {\"site\": 965, \"_stat_site_order\": 962}, {\"site\": 966, \"_stat_site_order\": 963}, {\"site\": 967, \"_stat_site_order\": 964}, {\"site\": 968, \"_stat_site_order\": 965}, {\"site\": 969, \"_stat_site_order\": 966}, {\"site\": 970, \"_stat_site_order\": 967}, {\"site\": 971, \"_stat_site_order\": 968}, {\"site\": 972, \"_stat_site_order\": 969}, {\"site\": 973, \"_stat_site_order\": 970}, {\"site\": 974, \"_stat_site_order\": 971}, {\"site\": 975, \"_stat_site_order\": 972}, {\"site\": 976, \"_stat_site_order\": 973}, {\"site\": 977, \"_stat_site_order\": 974}, {\"site\": 978, \"_stat_site_order\": 975}, {\"site\": 979, \"_stat_site_order\": 976}, {\"site\": 980, \"_stat_site_order\": 977}, {\"site\": 981, \"_stat_site_order\": 978}, {\"site\": 982, \"_stat_site_order\": 979}, {\"site\": 983, \"_stat_site_order\": 980}, {\"site\": 984, \"_stat_site_order\": 981}, {\"site\": 985, \"_stat_site_order\": 982}, {\"site\": 986, \"_stat_site_order\": 983}, {\"site\": 987, \"_stat_site_order\": 984}, {\"site\": 988, \"_stat_site_order\": 985}, {\"site\": 989, \"_stat_site_order\": 986}, {\"site\": 990, \"_stat_site_order\": 987}, {\"site\": 991, \"_stat_site_order\": 988}, {\"site\": 992, \"_stat_site_order\": 989}, {\"site\": 993, \"_stat_site_order\": 990}, {\"site\": 994, \"_stat_site_order\": 991}, {\"site\": 995, \"_stat_site_order\": 992}, {\"site\": 996, \"_stat_site_order\": 993}, {\"site\": 997, \"_stat_site_order\": 994}, {\"site\": 998, \"_stat_site_order\": 995}, {\"site\": 999, \"_stat_site_order\": 996}, {\"site\": 1000, \"_stat_site_order\": 997}, {\"site\": 1001, \"_stat_site_order\": 998}, {\"site\": 1002, \"_stat_site_order\": 999}, {\"site\": 1003, \"_stat_site_order\": 1000}, {\"site\": 1004, \"_stat_site_order\": 1001}, {\"site\": 1005, \"_stat_site_order\": 1002}, {\"site\": 1006, \"_stat_site_order\": 1003}, {\"site\": 1007, \"_stat_site_order\": 1004}, {\"site\": 1008, \"_stat_site_order\": 1005}, {\"site\": 1009, \"_stat_site_order\": 1006}, {\"site\": 1010, \"_stat_site_order\": 1007}, {\"site\": 1011, \"_stat_site_order\": 1008}, {\"site\": 1012, \"_stat_site_order\": 1009}, {\"site\": 1013, \"_stat_site_order\": 1010}, {\"site\": 1014, \"_stat_site_order\": 1011}, {\"site\": 1015, \"_stat_site_order\": 1012}, {\"site\": 1016, \"_stat_site_order\": 1013}, {\"site\": 1017, \"_stat_site_order\": 1014}, {\"site\": 1018, \"_stat_site_order\": 1015}, {\"site\": 1019, \"_stat_site_order\": 1016}, {\"site\": 1020, \"_stat_site_order\": 1017}, {\"site\": 1021, \"_stat_site_order\": 1018}, {\"site\": 1022, \"_stat_site_order\": 1019}, {\"site\": 1023, \"_stat_site_order\": 1020}, {\"site\": 1024, \"_stat_site_order\": 1021}, {\"site\": 1025, \"_stat_site_order\": 1022}, {\"site\": 1026, \"_stat_site_order\": 1023}, {\"site\": 1027, \"_stat_site_order\": 1024}, {\"site\": 1028, \"_stat_site_order\": 1025}, {\"site\": 1029, \"_stat_site_order\": 1026}, {\"site\": 1030, \"_stat_site_order\": 1027}, {\"site\": 1031, \"_stat_site_order\": 1028}, {\"site\": 1032, \"_stat_site_order\": 1029}, {\"site\": 1033, \"_stat_site_order\": 1030}, {\"site\": 1034, \"_stat_site_order\": 1031}, {\"site\": 1035, \"_stat_site_order\": 1032}, {\"site\": 1036, \"_stat_site_order\": 1033}, {\"site\": 1037, \"_stat_site_order\": 1034}, {\"site\": 1038, \"_stat_site_order\": 1035}, {\"site\": 1039, \"_stat_site_order\": 1036}, {\"site\": 1040, \"_stat_site_order\": 1037}, {\"site\": 1041, \"_stat_site_order\": 1038}, {\"site\": 1042, \"_stat_site_order\": 1039}, {\"site\": 1043, \"_stat_site_order\": 1040}, {\"site\": 1044, \"_stat_site_order\": 1041}, {\"site\": 1045, \"_stat_site_order\": 1042}, {\"site\": 1046, \"_stat_site_order\": 1043}, {\"site\": 1047, \"_stat_site_order\": 1044}, {\"site\": 1048, \"_stat_site_order\": 1045}, {\"site\": 1049, \"_stat_site_order\": 1046}, {\"site\": 1051, \"_stat_site_order\": 1047}, {\"site\": 1052, \"_stat_site_order\": 1048}, {\"site\": 1053, \"_stat_site_order\": 1049}, {\"site\": 1054, \"_stat_site_order\": 1050}, {\"site\": 1055, \"_stat_site_order\": 1051}, {\"site\": 1056, \"_stat_site_order\": 1052}, {\"site\": 1057, \"_stat_site_order\": 1053}, {\"site\": 1058, \"_stat_site_order\": 1054}, {\"site\": 1059, \"_stat_site_order\": 1055}, {\"site\": 1060, \"_stat_site_order\": 1056}, {\"site\": 1061, \"_stat_site_order\": 1057}, {\"site\": 1062, \"_stat_site_order\": 1058}, {\"site\": 1063, \"_stat_site_order\": 1059}, {\"site\": 1064, \"_stat_site_order\": 1060}, {\"site\": 1065, \"_stat_site_order\": 1061}, {\"site\": 1066, \"_stat_site_order\": 1062}, {\"site\": 1067, \"_stat_site_order\": 1063}, {\"site\": 1068, \"_stat_site_order\": 1064}, {\"site\": 1069, \"_stat_site_order\": 1065}, {\"site\": 1070, \"_stat_site_order\": 1066}, {\"site\": 1071, \"_stat_site_order\": 1067}, {\"site\": 1072, \"_stat_site_order\": 1068}, {\"site\": 1073, \"_stat_site_order\": 1069}, {\"site\": 1074, \"_stat_site_order\": 1070}, {\"site\": 1075, \"_stat_site_order\": 1071}, {\"site\": 1076, \"_stat_site_order\": 1072}, {\"site\": 1077, \"_stat_site_order\": 1073}, {\"site\": 1078, \"_stat_site_order\": 1074}, {\"site\": 1079, \"_stat_site_order\": 1075}, {\"site\": 1080, \"_stat_site_order\": 1076}, {\"site\": 1081, \"_stat_site_order\": 1077}, {\"site\": 1082, \"_stat_site_order\": 1078}, {\"site\": 1083, \"_stat_site_order\": 1079}, {\"site\": 1084, \"_stat_site_order\": 1080}, {\"site\": 1085, \"_stat_site_order\": 1081}, {\"site\": 1086, \"_stat_site_order\": 1082}, {\"site\": 1087, \"_stat_site_order\": 1083}, {\"site\": 1088, \"_stat_site_order\": 1084}, {\"site\": 1089, \"_stat_site_order\": 1085}, {\"site\": 1090, \"_stat_site_order\": 1086}, {\"site\": 1091, \"_stat_site_order\": 1087}, {\"site\": 1092, \"_stat_site_order\": 1088}, {\"site\": 1093, \"_stat_site_order\": 1089}, {\"site\": 1094, \"_stat_site_order\": 1090}, {\"site\": 1095, \"_stat_site_order\": 1091}, {\"site\": 1096, \"_stat_site_order\": 1092}, {\"site\": 1097, \"_stat_site_order\": 1093}, {\"site\": 1098, \"_stat_site_order\": 1094}, {\"site\": 1099, \"_stat_site_order\": 1095}, {\"site\": 1100, \"_stat_site_order\": 1096}, {\"site\": 1101, \"_stat_site_order\": 1097}, {\"site\": 1102, \"_stat_site_order\": 1098}, {\"site\": 1103, \"_stat_site_order\": 1099}, {\"site\": 1104, \"_stat_site_order\": 1100}, {\"site\": 1105, \"_stat_site_order\": 1101}, {\"site\": 1106, \"_stat_site_order\": 1102}, {\"site\": 1107, \"_stat_site_order\": 1103}, {\"site\": 1108, \"_stat_site_order\": 1104}, {\"site\": 1109, \"_stat_site_order\": 1105}, {\"site\": 1110, \"_stat_site_order\": 1106}, {\"site\": 1111, \"_stat_site_order\": 1107}, {\"site\": 1112, \"_stat_site_order\": 1108}, {\"site\": 1113, \"_stat_site_order\": 1109}, {\"site\": 1114, \"_stat_site_order\": 1110}, {\"site\": 1115, \"_stat_site_order\": 1111}, {\"site\": 1116, \"_stat_site_order\": 1112}, {\"site\": 1117, \"_stat_site_order\": 1113}, {\"site\": 1118, \"_stat_site_order\": 1114}, {\"site\": 1119, \"_stat_site_order\": 1115}, {\"site\": 1120, \"_stat_site_order\": 1116}, {\"site\": 1121, \"_stat_site_order\": 1117}, {\"site\": 1122, \"_stat_site_order\": 1118}, {\"site\": 1123, \"_stat_site_order\": 1119}, {\"site\": 1124, \"_stat_site_order\": 1120}, {\"site\": 1125, \"_stat_site_order\": 1121}, {\"site\": 1126, \"_stat_site_order\": 1122}, {\"site\": 1127, \"_stat_site_order\": 1123}, {\"site\": 1128, \"_stat_site_order\": 1124}, {\"site\": 1129, \"_stat_site_order\": 1125}, {\"site\": 1130, \"_stat_site_order\": 1126}, {\"site\": 1131, \"_stat_site_order\": 1127}, {\"site\": 1132, \"_stat_site_order\": 1128}, {\"site\": 1133, \"_stat_site_order\": 1129}, {\"site\": 1134, \"_stat_site_order\": 1130}, {\"site\": 1135, \"_stat_site_order\": 1131}, {\"site\": 1136, \"_stat_site_order\": 1132}, {\"site\": 1137, \"_stat_site_order\": 1133}, {\"site\": 1138, \"_stat_site_order\": 1134}, {\"site\": 1139, \"_stat_site_order\": 1135}, {\"site\": 1140, \"_stat_site_order\": 1136}, {\"site\": 1141, \"_stat_site_order\": 1137}, {\"site\": 1142, \"_stat_site_order\": 1138}, {\"site\": 1143, \"_stat_site_order\": 1139}, {\"site\": 1144, \"_stat_site_order\": 1140}, {\"site\": 1145, \"_stat_site_order\": 1141}, {\"site\": 1146, \"_stat_site_order\": 1142}, {\"site\": 1147, \"_stat_site_order\": 1143}, {\"site\": 1148, \"_stat_site_order\": 1144}, {\"site\": 1149, \"_stat_site_order\": 1145}, {\"site\": 1150, \"_stat_site_order\": 1146}, {\"site\": 1151, \"_stat_site_order\": 1147}, {\"site\": 1152, \"_stat_site_order\": 1148}, {\"site\": 1153, \"_stat_site_order\": 1149}, {\"site\": 1154, \"_stat_site_order\": 1150}, {\"site\": 1155, \"_stat_site_order\": 1151}, {\"site\": 1156, \"_stat_site_order\": 1152}, {\"site\": 1157, \"_stat_site_order\": 1153}, {\"site\": 1158, \"_stat_site_order\": 1154}, {\"site\": 1159, \"_stat_site_order\": 1155}, {\"site\": 1160, \"_stat_site_order\": 1156}, {\"site\": 1161, \"_stat_site_order\": 1157}, {\"site\": 1162, \"_stat_site_order\": 1158}, {\"site\": 1163, \"_stat_site_order\": 1159}, {\"site\": 1164, \"_stat_site_order\": 1160}, {\"site\": 1165, \"_stat_site_order\": 1161}, {\"site\": 1166, \"_stat_site_order\": 1162}, {\"site\": 1167, \"_stat_site_order\": 1163}, {\"site\": 1168, \"_stat_site_order\": 1164}, {\"site\": 1169, \"_stat_site_order\": 1165}, {\"site\": 1170, \"_stat_site_order\": 1166}, {\"site\": 1171, \"_stat_site_order\": 1167}, {\"site\": 1172, \"_stat_site_order\": 1168}, {\"site\": 1173, \"_stat_site_order\": 1169}, {\"site\": 1174, \"_stat_site_order\": 1170}, {\"site\": 1175, \"_stat_site_order\": 1171}, {\"site\": 1176, \"_stat_site_order\": 1172}, {\"site\": 1177, \"_stat_site_order\": 1173}, {\"site\": 1178, \"_stat_site_order\": 1174}, {\"site\": 1179, \"_stat_site_order\": 1175}, {\"site\": 1180, \"_stat_site_order\": 1176}, {\"site\": 1181, \"_stat_site_order\": 1177}, {\"site\": 1182, \"_stat_site_order\": 1178}, {\"site\": 1183, \"_stat_site_order\": 1179}, {\"site\": 1184, \"_stat_site_order\": 1180}, {\"site\": 1185, \"_stat_site_order\": 1181}, {\"site\": 1186, \"_stat_site_order\": 1182}, {\"site\": 1187, \"_stat_site_order\": 1183}, {\"site\": 1188, \"_stat_site_order\": 1184}, {\"site\": 1189, \"_stat_site_order\": 1185}, {\"site\": 1190, \"_stat_site_order\": 1186}, {\"site\": 1191, \"_stat_site_order\": 1187}, {\"site\": 1192, \"_stat_site_order\": 1188}, {\"site\": 1193, \"_stat_site_order\": 1189}, {\"site\": 1194, \"_stat_site_order\": 1190}, {\"site\": 1195, \"_stat_site_order\": 1191}, {\"site\": 1196, \"_stat_site_order\": 1192}, {\"site\": 1197, \"_stat_site_order\": 1193}, {\"site\": 1198, \"_stat_site_order\": 1194}, {\"site\": 1199, \"_stat_site_order\": 1195}, {\"site\": 1200, \"_stat_site_order\": 1196}, {\"site\": 1201, \"_stat_site_order\": 1197}, {\"site\": 1202, \"_stat_site_order\": 1198}, {\"site\": 1203, \"_stat_site_order\": 1199}, {\"site\": 1204, \"_stat_site_order\": 1200}, {\"site\": 1205, \"_stat_site_order\": 1201}, {\"site\": 1206, \"_stat_site_order\": 1202}, {\"site\": 1207, \"_stat_site_order\": 1203}, {\"site\": 1208, \"_stat_site_order\": 1204}, {\"site\": 1209, \"_stat_site_order\": 1205}, {\"site\": 1210, \"_stat_site_order\": 1206}, {\"site\": 1211, \"_stat_site_order\": 1207}, {\"site\": 1212, \"_stat_site_order\": 1208}, {\"site\": 1213, \"_stat_site_order\": 1209}, {\"site\": 1214, \"_stat_site_order\": 1210}, {\"site\": 1215, \"_stat_site_order\": 1211}, {\"site\": 1216, \"_stat_site_order\": 1212}, {\"site\": 1217, \"_stat_site_order\": 1213}, {\"site\": 1218, \"_stat_site_order\": 1214}, {\"site\": 1219, \"_stat_site_order\": 1215}, {\"site\": 1220, \"_stat_site_order\": 1216}, {\"site\": 1221, \"_stat_site_order\": 1217}, {\"site\": 1222, \"_stat_site_order\": 1218}, {\"site\": 1223, \"_stat_site_order\": 1219}, {\"site\": 1224, \"_stat_site_order\": 1220}, {\"site\": 1225, \"_stat_site_order\": 1221}, {\"site\": 1226, \"_stat_site_order\": 1222}, {\"site\": 1227, \"_stat_site_order\": 1223}, {\"site\": 1228, \"_stat_site_order\": 1224}, {\"site\": 1229, \"_stat_site_order\": 1225}, {\"site\": 1230, \"_stat_site_order\": 1226}, {\"site\": 1231, \"_stat_site_order\": 1227}, {\"site\": 1232, \"_stat_site_order\": 1228}, {\"site\": 1233, \"_stat_site_order\": 1229}, {\"site\": 1234, \"_stat_site_order\": 1230}, {\"site\": 1235, \"_stat_site_order\": 1231}, {\"site\": 1236, \"_stat_site_order\": 1232}, {\"site\": 1237, \"_stat_site_order\": 1233}, {\"site\": 1238, \"_stat_site_order\": 1234}, {\"site\": 1239, \"_stat_site_order\": 1235}, {\"site\": 1240, \"_stat_site_order\": 1236}, {\"site\": 1241, \"_stat_site_order\": 1237}, {\"site\": 1242, \"_stat_site_order\": 1238}, {\"site\": 1243, \"_stat_site_order\": 1239}, {\"site\": 1244, \"_stat_site_order\": 1240}, {\"site\": 1245, \"_stat_site_order\": 1241}, {\"site\": 1246, \"_stat_site_order\": 1242}, {\"site\": 1247, \"_stat_site_order\": 1243}, {\"site\": 1248, \"_stat_site_order\": 1244}, {\"site\": 1249, \"_stat_site_order\": 1245}, {\"site\": 1250, \"_stat_site_order\": 1246}], \"data-8e525cfd471f5c22b57d18fa5797760e\": [{\"site\": 1, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -0.003210063608130288, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": -2.2303, \"times_seen\": 1.0}, {\"site\": 1, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.0059975034842911145, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": -2.4823, \"times_seen\": 2.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -5.494290470672694e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.0498, \"times_seen\": 2.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.009959990763751586, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.2451, \"times_seen\": 14.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.009491681675759709, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.382, \"times_seen\": 14.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.023693211856113228, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.3639, \"times_seen\": 4.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0277749615742787, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": 0.0936, \"times_seen\": 19.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.002387404434733009, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.1408, \"times_seen\": 1.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.042932967905176506, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.263, \"times_seen\": 91.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.5631187114552024, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.0572, \"times_seen\": 62.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.1704328651126882, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.1162, \"times_seen\": 69.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.011748904671067439, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.052, \"times_seen\": 40.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.011475765439981718, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.1206, \"times_seen\": 11.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.0019579052417658125, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.0643147925851137, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.1365, \"times_seen\": 35.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.021991968969848737, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.1702, \"times_seen\": 26.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 1.0529840336357004, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": -0.4127, \"times_seen\": 28.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.025012495868643396, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": -0.3325, \"times_seen\": 10.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": 0.005149894860176321, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": -0.014660418807461025, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.3095, \"times_seen\": 61.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.09128715300414059, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2806, \"times_seen\": 42.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": -0.0006044324043889246, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -1.3074, \"times_seen\": 5.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": 0.007648489415519515, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -1.5861, \"times_seen\": 7.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.07110755511625519, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.397, \"times_seen\": 54.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": -1.022801199866344, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.1809, \"times_seen\": 40.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.09282400982432598, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2581, \"times_seen\": 53.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.012482055328735525, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.3636, \"times_seen\": 60.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.008136144810303435, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -2.9296, \"times_seen\": 1.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.29694823460933817, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.2568, \"times_seen\": 44.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": -0.05300575696637808, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.0041, \"times_seen\": 22.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.5634812652698379, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -1.1555, \"times_seen\": 115.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 1.0928557530091254, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.6278, \"times_seen\": 2.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.5022154665999965, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.369, \"times_seen\": 86.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.2148151736154092, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.0821, \"times_seen\": 97.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.08727816908038538, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2298, \"times_seen\": 85.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.03797216451043905, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2278, \"times_seen\": 57.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.07819749745470835, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.1663, \"times_seen\": 27.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.01164821367001458, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.3396, \"times_seen\": 31.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.0032583888375961696, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.013256955728940537, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.2169, \"times_seen\": 72.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.011116858769018778, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3016, \"times_seen\": 18.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.036563980093455455, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3019, \"times_seen\": 54.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.008597064632221289, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.374, \"times_seen\": 58.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.00022195173809518414, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.397, \"times_seen\": 44.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.06542123649088373, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3992, \"times_seen\": 16.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"W\", \"escape\": -0.003623587466403715, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.2707, \"times_seen\": 1.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.08104144040581697, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.187, \"times_seen\": 57.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.012713123544109955, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.2303, \"times_seen\": 11.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.004475420110500045, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.2428, \"times_seen\": 1.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.011568657176710673, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -2.1974, \"times_seen\": 3.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -1.5087606504851565, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -0.7435, \"times_seen\": 31.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.02073811252000829, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": 0.0972, \"times_seen\": 8.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.010913130135830252, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -2.4719, \"times_seen\": 5.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.012745218120320026, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -0.6371, \"times_seen\": 10.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": -0.01995888104883613, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -0.2813, \"times_seen\": 19.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.2306638559224917, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.1735, \"times_seen\": 93.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.09685662263132014, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.1042, \"times_seen\": 17.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.025629683729898507, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.0833, \"times_seen\": 14.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.011187110378953775, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.2579, \"times_seen\": 50.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.33488039443437523, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.0953, \"times_seen\": 78.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"-\", \"escape\": -5.129512024784102e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.2833, \"times_seen\": 1.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.07156925778889527, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.4444, \"times_seen\": 57.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.014929408174894014, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.2022, \"times_seen\": 9.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.03645330664583479, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": -0.8768, \"times_seen\": 11.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.0009454474554370636, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.1603, \"times_seen\": 3.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.007813961403986776, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": -0.1532, \"times_seen\": 6.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.040386233025655666, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.3729, \"times_seen\": 39.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.001664458018705095, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": -0.1303, \"times_seen\": 5.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.03162212078796105, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.3549, \"times_seen\": 45.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.03421471739462403, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.4444, \"times_seen\": 32.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.3279656454451281, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.2851, \"times_seen\": 57.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.04543213238258896, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": -0.084545992745953, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.0913, \"times_seen\": 1.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": 0.0031607238338348916, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": -0.2745, \"times_seen\": 8.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.019205586160088547, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.0764, \"times_seen\": 32.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.006203990508942134, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2192, \"times_seen\": 47.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -0.00933146750677828, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0764, \"times_seen\": 3.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.01901675376609127, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.1186, \"times_seen\": 6.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.03799361407522779, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.1239, \"times_seen\": 73.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.004482533381641296, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.103, \"times_seen\": 8.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.018007175276489065, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2061, \"times_seen\": 7.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.017601645094253958, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.1301, \"times_seen\": 9.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.009434493420207383, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0061, \"times_seen\": 4.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.25003312845997505, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0117, \"times_seen\": 36.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.01344099017819831, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.0662, \"times_seen\": 6.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.0013067997241463021, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2492, \"times_seen\": 12.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.01951697296441464, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.0798, \"times_seen\": 63.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.007423155503340385, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.5121, \"times_seen\": 3.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.02774212761322606, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2823, \"times_seen\": 22.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.016055157873382284, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0059, \"times_seen\": 44.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.03518075321744353, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.3056, \"times_seen\": 13.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.0039754583005256056, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0421, \"times_seen\": 1.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.037770465828144625, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2352, \"times_seen\": 47.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.08335776206399594, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.401, \"times_seen\": 15.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.026023231183333734, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0129, \"times_seen\": 15.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -0.006852104542441199, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": 0.004779370675533709, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.2161, \"times_seen\": 5.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.012866858452505053, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.1084, \"times_seen\": 6.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.04081072627515694, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.029, \"times_seen\": 40.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.003761427974774522, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0421, \"times_seen\": 20.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.019840130848642935, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.1889, \"times_seen\": 3.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.1538602972166953, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.289, \"times_seen\": 20.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.019912653799509822, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.1308, \"times_seen\": 7.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.02859056584665776, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.005, \"times_seen\": 24.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.003318065722933992, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.3762, \"times_seen\": 3.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.006269973995981175, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.2887, \"times_seen\": 2.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.009482858159875044, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.5151, \"times_seen\": 16.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.011583637896150282, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.2847, \"times_seen\": 6.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 0.015378025608551036, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0634, \"times_seen\": 23.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.00885516553514669, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.2438, \"times_seen\": 8.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.0028966979041311187, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.0454, \"times_seen\": 1.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.06815619397119917, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.4201, \"times_seen\": 72.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.0008968948603200261, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.013671130446495509, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.4294, \"times_seen\": 18.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.008977961588157038, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": -0.1732, \"times_seen\": 45.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"-\", \"escape\": 0.00826732492134555, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.418, \"times_seen\": 11.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -1.140782073460753, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.2209, \"times_seen\": 73.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": -0.03562690883646618, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": -0.186, \"times_seen\": 6.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.3219682371046515, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.251, \"times_seen\": 11.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": 0.004897516712307779, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.1163, \"times_seen\": 16.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": -0.003193861047312989, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.1541, \"times_seen\": 1.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": 0.024117654895673423, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.0628, \"times_seen\": 28.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": 0.008095042177080226, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.0431, \"times_seen\": 23.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.06683963546774555, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": -0.1663, \"times_seen\": 68.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.08335075541575371, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0322, \"times_seen\": 65.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.025385751188330537, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0386, \"times_seen\": 49.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.019751801278392118, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": -0.0772, \"times_seen\": 42.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.01040852018685356, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.2404, \"times_seen\": 22.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.089327339187058, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": -0.136, \"times_seen\": 17.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.20004072640891388, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.376, \"times_seen\": 60.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.004819991977649433, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.5785, \"times_seen\": 11.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.15632760805441148, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.4162, \"times_seen\": 36.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": -0.00020984201086720754, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.511, \"times_seen\": 9.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.04227430390814062, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.554, \"times_seen\": 31.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.029003780936660496, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.5979, \"times_seen\": 19.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.0017054998458219874, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": 0.0501, \"times_seen\": 1.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": -0.07876202158033727, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1471, \"times_seen\": 45.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": 0.004424287447654921, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.6401, \"times_seen\": 21.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": -0.009895948628757886, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.2457, \"times_seen\": 13.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": -0.014060376426203695, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0624, \"times_seen\": 26.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.18972288620207906, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0948, \"times_seen\": 42.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": -0.06556340422457994, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.2994, \"times_seen\": 25.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.005610784182014543, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.2382, \"times_seen\": 24.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0007302326763253544, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1222, \"times_seen\": 25.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.034563159536507015, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.2198, \"times_seen\": 55.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.005011917200087582, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0761, \"times_seen\": 38.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": -0.010848178334491053, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.3196, \"times_seen\": 9.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.4444530447772094, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.031, \"times_seen\": 147.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.03577832093905901, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1973, \"times_seen\": 51.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.06001661232347318, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1738, \"times_seen\": 65.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.446702589995606, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0239, \"times_seen\": 50.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.02046012274209871, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0798, \"times_seen\": 47.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.1286699930930061, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.017, \"times_seen\": 51.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.05838929909905208, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0637, \"times_seen\": 27.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.0035960811362916252, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1084, \"times_seen\": 14.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"*\", \"escape\": -0.0011821039266554012, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.0032395675600685532, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0466, \"times_seen\": 1.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.2891059399207395, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.24, \"times_seen\": 89.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.030719241366881013, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.6944, \"times_seen\": 24.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.06258595094658849, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0872, \"times_seen\": 13.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": 1.4008949765861487, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.3967, \"times_seen\": 7.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.003050597640131555, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.2889, \"times_seen\": 31.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.03059420339559622, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.3205, \"times_seen\": 24.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.0074202691807516985, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.9589, \"times_seen\": 20.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.0031460436488295273, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.2361, \"times_seen\": 81.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.5702980885710885, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.2149, \"times_seen\": 54.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.16129091865249692, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.2714, \"times_seen\": 60.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.0018267124974701782, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.03, \"times_seen\": 25.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.018878136617981205, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.1833, \"times_seen\": 49.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.012166482431574714, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.0513, \"times_seen\": 105.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.0645175991051724, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.5133, \"times_seen\": 17.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.005887005098176949, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.0266, \"times_seen\": 91.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.28201215574049365, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.3007, \"times_seen\": 133.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.007806482315359312, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.1003, \"times_seen\": 17.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": -0.024547983776858216, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0735, \"times_seen\": 21.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.28768751630333445, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.0945, \"times_seen\": 25.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.007344471794681002, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -3.0652, \"times_seen\": 3.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.0018667195556996996, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.11622615867236734, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.2419, \"times_seen\": 60.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.12325520335958808, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.2046, \"times_seen\": 77.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.13818539482758868, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.383, \"times_seen\": 82.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.023106402097784754, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": -0.0425, \"times_seen\": 28.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.04328224565882728, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.0782, \"times_seen\": 12.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.002886987632767349, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.028048537773908266, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3483, \"times_seen\": 35.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.08726039105749027, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3186, \"times_seen\": 138.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": 0.026057348929841153, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.0568, \"times_seen\": 78.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.28736414314351205, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3517, \"times_seen\": 97.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.0020744144468529658, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.157, \"times_seen\": 5.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": -0.001788211678950402, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3257, \"times_seen\": 1.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.03261908539783589, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": -0.0945, \"times_seen\": 130.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.34551149594888164, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.1923, \"times_seen\": 105.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.003142370474465673, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.2954, \"times_seen\": 3.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": -0.0003329403326038064, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.14885336624248363, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": -0.2283, \"times_seen\": 109.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.1393537175270399, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.1231, \"times_seen\": 79.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.013592786800648548, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.1078, \"times_seen\": 7.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.07130973126287887, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": -0.1722, \"times_seen\": 83.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.07150511088139443, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": -0.1872, \"times_seen\": 24.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.01970316133729787, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.1051, \"times_seen\": 23.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.021260438755230704, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0926, \"times_seen\": 15.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.07997000511296395, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0352, \"times_seen\": 141.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.20805093656670498, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.1144, \"times_seen\": 36.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.1209181105070473, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0207, \"times_seen\": 62.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": 0.00754780129938775, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0088, \"times_seen\": 28.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.07768777304936356, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -0.2311, \"times_seen\": 30.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.03651659992174951, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -0.0953, \"times_seen\": 60.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": 0.014671731691922475, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -2.3803, \"times_seen\": 2.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.12527911262447747, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.2565, \"times_seen\": 36.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.005340395476255752, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.2929, \"times_seen\": 1.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.010528736592664253, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.4616, \"times_seen\": 23.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.0008131092703392492, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.0642, \"times_seen\": 2.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.006566323978337521, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.004650398965915061, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.0902, \"times_seen\": 1.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.0433392416671939, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.1515, \"times_seen\": 23.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0004977630972126227, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.1116, \"times_seen\": 3.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.0549173198149963, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.1582, \"times_seen\": 14.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.854417430237285, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.0184, \"times_seen\": 59.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.010748104021070733, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.15777369106012257, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.0359, \"times_seen\": 106.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.42149268154183817, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.0811, \"times_seen\": 119.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": 0.002173638692505969, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.007020373918802704, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.1673, \"times_seen\": 73.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.6356138969920898, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.2096, \"times_seen\": 102.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"-\", \"escape\": -0.1510155479662008, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.0124, \"times_seen\": 91.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.21500000041179143, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0665, \"times_seen\": 177.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"C\", \"escape\": -0.1984056706042474, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.25, \"times_seen\": 43.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"D\", \"escape\": -0.8078420773731256, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0853, \"times_seen\": 38.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"E\", \"escape\": -0.028688523311772435, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.1077, \"times_seen\": 73.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"F\", \"escape\": -0.3226264690924935, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.1031, \"times_seen\": 73.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": -0.011316939518490108, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.2147, \"times_seen\": 110.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.0005038235862687368, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.082, \"times_seen\": 157.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"I\", \"escape\": -0.016403505905986812, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0365, \"times_seen\": 47.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"K\", \"escape\": -0.10648237803048279, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.11, \"times_seen\": 62.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.04200998039015386, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0377, \"times_seen\": 300.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": -0.6720506940522146, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0335, \"times_seen\": 74.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"N\", \"escape\": -0.09022790092922091, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.2281, \"times_seen\": 43.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.22778448849947866, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.125, \"times_seen\": 96.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.13554013331811257, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0945, \"times_seen\": 207.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.03398245900213996, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0988, \"times_seen\": 185.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.06437364885501143, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0287, \"times_seen\": 161.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": 0.01311393947538878, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0265, \"times_seen\": 122.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"W\", \"escape\": 0.020998189941332627, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.2387, \"times_seen\": 26.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"Y\", \"escape\": -0.11488417366389783, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.033, \"times_seen\": 53.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"*\", \"escape\": -0.04549011862209278, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -2.9872, \"times_seen\": 8.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.18002901136674865, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.1383, \"times_seen\": 5.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.0605013186632238, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.081, \"times_seen\": 11.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.01623301852519959, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": 0.0321, \"times_seen\": 27.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.00506009030187544, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.2663, \"times_seen\": 13.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.03614258291031205, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.7404, \"times_seen\": 29.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.075673814789383, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.2984, \"times_seen\": 57.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.010824388245261475, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.1758, \"times_seen\": 107.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.017072920281002858, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.2406, \"times_seen\": 70.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.12196488805464262, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.1402, \"times_seen\": 34.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": 0.014550172343084934, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.1212, \"times_seen\": 26.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.01274250082453247, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.0107, \"times_seen\": 25.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.2514842769646186, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.2076, \"times_seen\": 147.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.002699416945765566, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.3199, \"times_seen\": 1.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.05614341036288643, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.034, \"times_seen\": 30.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -0.0017488092951035217, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.2182, \"times_seen\": 1.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.02122377275520172, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0217, \"times_seen\": 135.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.001474404010646012, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": 0.0151, \"times_seen\": 37.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": 0.06918417950165145, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.9919, \"times_seen\": 35.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": 0.04092397988345838, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.6248, \"times_seen\": 22.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.1606853739052702, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.3225, \"times_seen\": 60.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.006868192697833793, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2236, \"times_seen\": 19.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.1405685442359473, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2165, \"times_seen\": 76.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.131986940550807, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.1728, \"times_seen\": 144.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.027880241988650637, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0741, \"times_seen\": 29.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.1348524550488482, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2727, \"times_seen\": 120.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.06011106445261562, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0634, \"times_seen\": 31.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.030123513470157372, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -1.1027, \"times_seen\": 54.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.1286078619951211, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.7726, \"times_seen\": 117.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.03985723059542733, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2614, \"times_seen\": 22.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.08621493994938614, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0754, \"times_seen\": 56.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.005344082952106071, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.1188, \"times_seen\": 187.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": 0.04460947355239984, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.1554, \"times_seen\": 63.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": -0.05991896367255191, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.3719, \"times_seen\": 28.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -1.440025854403291, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2473, \"times_seen\": 56.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": 0.01873947966587945, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -2.7073, \"times_seen\": 1.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.09250258822954771, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.2915, \"times_seen\": 19.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.003931629595987716, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -1.4364, \"times_seen\": 1.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.014355687470171524, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.1785, \"times_seen\": 95.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.01624840730543714, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.0096, \"times_seen\": 25.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.008401037529457842, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.1346, \"times_seen\": 72.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": 0.0074579483151570435, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.1372, \"times_seen\": 13.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.11447196768044397, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.1031, \"times_seen\": 93.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.027566831322974113, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.0444, \"times_seen\": 42.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.08882513588953486, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.1011, \"times_seen\": 33.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.048755454475817625, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -1.6643, \"times_seen\": 14.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.129026135727893, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -0.6806, \"times_seen\": 12.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.01910406378808726, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -2.6768, \"times_seen\": 1.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.009183191945355003, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -0.5595, \"times_seen\": 3.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.014370654089455946, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -2.2492, \"times_seen\": 3.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.019079521535784443, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.3272, \"times_seen\": 4.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.08002789745314987, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.8860855908774602, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.2503, \"times_seen\": 32.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.00816102887469919, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.2702, \"times_seen\": 7.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.4285395395919357, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -0.0009, \"times_seen\": 27.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.10563859265975704, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.5022, \"times_seen\": 11.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.044859259672216004, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.3319, \"times_seen\": 74.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.09184797848022475, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.0638, \"times_seen\": 14.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.015159168198438294, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.0747, \"times_seen\": 4.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.2721722159471126, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.1335, \"times_seen\": 6.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.013381770463052948, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.1264, \"times_seen\": 16.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.005425015441205747, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.913, \"times_seen\": 3.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.04061941548266109, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -2.8329, \"times_seen\": 2.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": 0.011087752843592792, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": 0.0507, \"times_seen\": 7.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.011253254940412431, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -0.6047, \"times_seen\": 13.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.004737479297302444, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.2083, \"times_seen\": 15.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.00807369895734798, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -2.7512, \"times_seen\": 3.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"P\", \"escape\": -0.0037431339170160825, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -2.963, \"times_seen\": 1.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.001827429987247873, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.472, \"times_seen\": 1.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.023501827857882296, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.6049, \"times_seen\": 3.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.2779144020543327, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.7398, \"times_seen\": 31.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.008660855057833634, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -2.2796, \"times_seen\": 7.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.04060352145604505, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.2414, \"times_seen\": 15.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.029625901679908424, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.5298, \"times_seen\": 21.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0055105164578025684, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.2626, \"times_seen\": 14.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.0014411856255625828, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.2184, \"times_seen\": 7.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.09809223310648381, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.3847, \"times_seen\": 33.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.16435516114834708, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": 0.2168, \"times_seen\": 79.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.013160876246045023, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": 0.1621, \"times_seen\": 4.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.004132703353956702, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.0959, \"times_seen\": 9.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.0005460813134504153, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -1.4704, \"times_seen\": 1.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.0017297345140945934, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -0.9055, \"times_seen\": 5.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.02835910238789418, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -0.2204, \"times_seen\": 18.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.01707086255716493, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.3453, \"times_seen\": 2.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.009419631034715693, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.9696, \"times_seen\": 2.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.013380057702330844, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.812, \"times_seen\": 2.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.04911564095977561, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -2.6265, \"times_seen\": 3.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.012007071400304232, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -0.0741, \"times_seen\": 4.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.0024912157761069463, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -1.4529, \"times_seen\": 5.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.00991320357836521, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -0.5605, \"times_seen\": 3.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.0030572996453502137, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.37, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": -0.0063237940111489825, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.2309, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 0.010308649683712267, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.2172, \"times_seen\": 4.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.026490441274050636, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -1.6753, \"times_seen\": 4.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"N\", \"escape\": -0.004764424769438443, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": 0.35, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.0027395803100114116, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -1.1557, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.01507859470237607, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": 0.3631, \"times_seen\": 36.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0013150358366416813, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.0649, \"times_seen\": 20.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.03524018057558795, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.0319, \"times_seen\": 5.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.02791234591017717, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.0019, \"times_seen\": 2.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 2.60246754915718, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.6738, \"times_seen\": 6.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.0617218530328155, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -2.2738, \"times_seen\": 1.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.010976568403843725, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.6505, \"times_seen\": 12.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.013131659784821215, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.4399, \"times_seen\": 8.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.010547455214503303, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.3101, \"times_seen\": 1.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.029903013356366553, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": 0.1298, \"times_seen\": 29.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": -0.002471352246812624, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.2988, \"times_seen\": 2.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.04046143317464507, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.2941, \"times_seen\": 11.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.003253794421255817, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.0335, \"times_seen\": 25.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.0007851838561844711, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.6873, \"times_seen\": 1.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.03260619417487708, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -2.0016, \"times_seen\": 2.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.01612161802904399, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.0842690429646974, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.3356, \"times_seen\": 25.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.010834233786016485, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.3644, \"times_seen\": 4.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.005711524577445347, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.0304, \"times_seen\": 5.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": -0.03947038210560808, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -1.3902, \"times_seen\": 6.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": -0.007159438083924563, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -0.8912, \"times_seen\": 1.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.005984724757275251, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -0.3052, \"times_seen\": 4.0}, {\"site\": 43, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.8371793673707494, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": 0.171, \"times_seen\": 8.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.03768636554943352, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -3.1109, \"times_seen\": 2.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.0014520162779930507, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -2.5511, \"times_seen\": 1.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.009550622022327157, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -1.3754, \"times_seen\": 14.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.0025560282965361807, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -1.3611, \"times_seen\": 3.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": 0.0023981068260614945, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -1.7575, \"times_seen\": 4.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.014167015694481986, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -2.5003, \"times_seen\": 2.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0036216970047926412, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": 0.032, \"times_seen\": 15.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.06883434114548179, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.6868, \"times_seen\": 35.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.021771410421820653, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.596, \"times_seen\": 5.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.2530590809311016, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -1.1187, \"times_seen\": 26.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.1882856049798627, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.5499, \"times_seen\": 36.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.023054577673545254, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.2105, \"times_seen\": 20.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -1.7417204069964167, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.0387, \"times_seen\": 4.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.012085474118110225, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -2.7094, \"times_seen\": 1.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.00889265131664476, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -0.1556, \"times_seen\": 4.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.07083907411602758, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -2.2301, \"times_seen\": 12.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.009737200055617614, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -0.9944, \"times_seen\": 4.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.004550423352208061, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.07978977695703034, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -2.5774, \"times_seen\": 17.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.00808912888982783, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.0297, \"times_seen\": 5.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.02520111047815043, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.1629, \"times_seen\": 6.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.0009347600313531932, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.5387, \"times_seen\": 11.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.2048424328404268, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.4671, \"times_seen\": 2.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.05647125641877577, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.1979, \"times_seen\": 30.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.012081783703923741, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.3864, \"times_seen\": 5.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": -0.021072214550024827, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.1746, \"times_seen\": 7.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.0033462352224935235, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.2582, \"times_seen\": 2.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.6099741226982259, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.0317, \"times_seen\": 3.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.0060822887507617305, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.8417, \"times_seen\": 2.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.0003097911141256575, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.2817, \"times_seen\": 3.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.057786634726304964, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -1.8053, \"times_seen\": 10.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.007390438019664007, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.17, \"times_seen\": 2.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": 0.01070048465255307, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.3694, \"times_seen\": 2.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.0037994958925250235, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.6601, \"times_seen\": 2.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"A\", \"escape\": 0.001208595095992242, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.2204, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"C\", \"escape\": 0.06688558542025677, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.2969, \"times_seen\": 21.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"I\", \"escape\": -0.012192159945309911, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": 0.009927790040512386, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.0998, \"times_seen\": 20.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.003551525130574834, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -2.7292, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": 0.018254893095493697, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -2.5739, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": 0.10968326857699365, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.0067, \"times_seen\": 39.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.042772993836439725, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": 0.05439640373581071, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -1.4669, \"times_seen\": 3.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"T\", \"escape\": -0.00732415091226248, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.026, \"times_seen\": 3.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"W\", \"escape\": 0.012585604727564823, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.2159, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.010231848249871561, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.1723, \"times_seen\": 20.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.007834541406563787, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0423, \"times_seen\": 2.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.002758042279952057, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.5661, \"times_seen\": 2.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.019352533209335537, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.3996, \"times_seen\": 10.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.04847755851469097, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.0512, \"times_seen\": 20.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.0020952448736099847, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0653, \"times_seen\": 2.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.010363521883867553, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.4275, \"times_seen\": 5.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.5237043574573336, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.1203, \"times_seen\": 45.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.04110850503949122, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.1371, \"times_seen\": 33.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.004816582284077147, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -1.2814, \"times_seen\": 7.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.004671877835629921, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0492, \"times_seen\": 9.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.048187357076636794, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.00693338946429035, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.020047928823747112, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": -0.0949, \"times_seen\": 24.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.019376764264933576, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.3228, \"times_seen\": 6.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.02602458508369558, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.0009, \"times_seen\": 3.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.06709518815907778, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": -1.0619, \"times_seen\": 22.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.7531814212344846, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.3659, \"times_seen\": 64.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.009790693505920036, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.042, \"times_seen\": 6.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.050039494854274176, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": -0.0164, \"times_seen\": 29.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.017607605047703208, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.0047, \"times_seen\": 16.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.0621467025524039, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.1996, \"times_seen\": 23.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": 0.02216335394718211, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.3851, \"times_seen\": 3.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.009251871083247837, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": -0.3682, \"times_seen\": 13.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.08213175651571088, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.1243, \"times_seen\": 4.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.056650024361657586, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.0635, \"times_seen\": 34.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.15937369188606448, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.0979, \"times_seen\": 173.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.005769665913499919, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": -2.8725, \"times_seen\": 5.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.016371923471722737, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.2798, \"times_seen\": 11.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.013742072219093873, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": 0.0382, \"times_seen\": 7.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.38973800407165976, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -2.1354, \"times_seen\": 14.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0015719192780383102, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -1.0069, \"times_seen\": 2.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.029356214865940474, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.7697, \"times_seen\": 12.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": -0.028928424182279748, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": 0.1398, \"times_seen\": 6.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": 0.024705302040396525, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.5728, \"times_seen\": 2.0}, {\"site\": 55, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.006179383023651771, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -0.7282, \"times_seen\": 2.0}, {\"site\": 55, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.05171127154023689, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": 0.2628, \"times_seen\": 20.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.009411253551323712, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -1.7867, \"times_seen\": 6.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.00016749274209890922, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -0.2693, \"times_seen\": 5.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.04204875135243803, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": 0.1187, \"times_seen\": 5.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.0013711991993328814, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -2.2717, \"times_seen\": 4.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.003876866176098943, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -0.3305, \"times_seen\": 1.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0007321413238259171, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -0.0474, \"times_seen\": 13.0}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.0022191057091070472, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -2.8649, \"times_seen\": 1.0}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.00895853227249683, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -1.402, \"times_seen\": 12.0}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.013594125203446761, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -1.9551, \"times_seen\": 2.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": 0.04113026673194098, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -2.9909, \"times_seen\": 3.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.0026658513999431284, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -0.6816, \"times_seen\": 10.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.009154678058189447, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -1.1986, \"times_seen\": 4.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.0379323882763538, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -1.701, \"times_seen\": 1.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.004547878351606691, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -0.1, \"times_seen\": 1.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.013045361594832244, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -2.142, \"times_seen\": 1.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.1004473755269247, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -0.1372, \"times_seen\": 28.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.03258770109893997, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": 0.2057, \"times_seen\": 24.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.021360868554669468, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -0.0095, \"times_seen\": 35.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.00430552354340416, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.2894, \"times_seen\": 15.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.004361030896565805, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.4102, \"times_seen\": 18.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.006984773505908683, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -1.6135, \"times_seen\": 34.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.006246137912522223, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.4363, \"times_seen\": 12.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.005204246766837473, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.5157, \"times_seen\": 2.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.005068524496535976, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -2.112, \"times_seen\": 2.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.020354234367151537, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.3375, \"times_seen\": 15.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.003578920540413286, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -2.9879, \"times_seen\": 1.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.024294810237112628, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -1.0799, \"times_seen\": 3.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.029185044235049716, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.0547, \"times_seen\": 21.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.011269632899253364, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.1119, \"times_seen\": 8.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.013227414133876365, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.192, \"times_seen\": 7.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.0008384514588444207, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.1077, \"times_seen\": 29.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.09176857177703833, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.2256, \"times_seen\": 16.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.007567752024167796, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.0966, \"times_seen\": 16.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"W\", \"escape\": 0.005072939512625435, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -1.2228, \"times_seen\": 5.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.00351552077863905, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -0.5063, \"times_seen\": 18.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": -0.002791418483688483, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -2.1029, \"times_seen\": 2.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.0009917518073287788, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -2.957, \"times_seen\": 1.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.013837244072055967, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -1.0437, \"times_seen\": 30.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -8.9662261123689e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -0.8009, \"times_seen\": 11.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.6533307849412474, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": 0.0795, \"times_seen\": 54.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.042704190266826064, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -0.0591, \"times_seen\": 84.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.18188186002865186, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": 0.0445, \"times_seen\": 21.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": 0.0650449665665439, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -1.2254, \"times_seen\": 6.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.006085020526335226, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1278, \"times_seen\": 16.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.06544119805202195, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.3034, \"times_seen\": 50.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.016644045509159856, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.7167, \"times_seen\": 5.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.08213194980233873, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1516, \"times_seen\": 24.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": 0.027923988410755853, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.2228, \"times_seen\": 5.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.07737775768655654, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1262, \"times_seen\": 17.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.004430179308766038, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1452, \"times_seen\": 15.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": 0.01028910636126223, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.0504, \"times_seen\": 94.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": 0.07248366222952855, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.0032, \"times_seen\": 19.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"G\", \"escape\": -0.02333422054746733, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.0158, \"times_seen\": 15.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"K\", \"escape\": 0.03927405417979859, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.1005, \"times_seen\": 23.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": 0.003136293083825064, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.0708, \"times_seen\": 101.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.20071486547531378, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.1623, \"times_seen\": 122.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"S\", \"escape\": 0.004925111454241618, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.0457, \"times_seen\": 20.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": -0.009590586657981091, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -2.6819, \"times_seen\": 2.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"-\", \"escape\": -1.9765948515423595, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.1828, \"times_seen\": 20.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.8118699408169544, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.2315, \"times_seen\": 24.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.006778614140033231, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.1169, \"times_seen\": 1.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.019549785141050754, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.0363, \"times_seen\": 31.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.02653793073759678, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.5773, \"times_seen\": 14.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.006534162223732606, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.0132, \"times_seen\": 9.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.012651911627642702, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.1808, \"times_seen\": 35.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": -0.034046373787009206, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.2061, \"times_seen\": 17.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": 0.02373511065721062, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.0423, \"times_seen\": 15.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"F\", \"escape\": 0.0388679816889105, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.113, \"times_seen\": 26.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"M\", \"escape\": -0.0587819344465365, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.0595, \"times_seen\": 24.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.178845383468812, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.1133, \"times_seen\": 44.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": -0.005256872002824101, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.1817, \"times_seen\": 13.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": -0.034800135227227816, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.0272, \"times_seen\": 15.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.2737671378182315, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.0116, \"times_seen\": 39.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.14144551970074254, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.1116, \"times_seen\": 117.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"-\", \"escape\": 0.09512342207770978, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.1132, \"times_seen\": 30.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.08772260494375075, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.1023, \"times_seen\": 220.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": 0.02165949049905377, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.3216, \"times_seen\": 99.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": -2.611035961619245, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.033, \"times_seen\": 115.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.05499960163337857, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0541, \"times_seen\": 110.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.9896999281035167, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0415, \"times_seen\": 89.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.006453413127367956, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0284, \"times_seen\": 116.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"H\", \"escape\": 0.011723583657729526, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0483, \"times_seen\": 63.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.5659943386748152, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0065, \"times_seen\": 106.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"K\", \"escape\": -0.10594332193705791, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.3331, \"times_seen\": 58.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.10090839486963175, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0207, \"times_seen\": 188.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.3052620003451318, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0777, \"times_seen\": 82.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"N\", \"escape\": 0.0248565110770081, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0498, \"times_seen\": 68.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"P\", \"escape\": 0.10243930476402946, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0876, \"times_seen\": 152.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": 0.007132574419310279, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0541, \"times_seen\": 57.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": 0.03514988339741375, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.1584, \"times_seen\": 122.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.010078685766930414, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0764, \"times_seen\": 270.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.19383364381068124, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0328, \"times_seen\": 193.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"W\", \"escape\": -0.09575874042211532, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0267, \"times_seen\": 63.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.10392540355611625, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0282, \"times_seen\": 63.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"*\", \"escape\": -0.009019078453325004, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -2.6734, \"times_seen\": 5.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.08179739047348952, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.1529, \"times_seen\": 19.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"C\", \"escape\": -0.02010006742065789, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.008, \"times_seen\": 11.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.016403797160412535, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.1689, \"times_seen\": 16.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": -0.01224475570122317, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.2093, \"times_seen\": 7.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.013605984265609024, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.2424, \"times_seen\": 25.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.045478242625380375, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0642, \"times_seen\": 37.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.030750252062029183, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.1163, \"times_seen\": 16.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"R\", \"escape\": -0.017286665365135127, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.094, \"times_seen\": 22.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.22407953337951353, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0391, \"times_seen\": 106.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.0001344351081021279, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0412, \"times_seen\": 23.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.00614993365751616, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.0902, \"times_seen\": 19.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.06125116003451343, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0795, \"times_seen\": 15.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.45746651919474096, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.1456, \"times_seen\": 56.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": 0.008547016766534526, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.3574, \"times_seen\": 8.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.018552323446585535, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0848, \"times_seen\": 63.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.009611049604572926, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": -0.0858, \"times_seen\": 12.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.025175692703350395, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0396, \"times_seen\": 69.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.01896093740941715, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0112, \"times_seen\": 15.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.0009591206197540309, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.04, \"times_seen\": 12.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.13742004244294742, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.1375, \"times_seen\": 93.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 0.17175885244538924, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0673, \"times_seen\": 21.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.23420153663418883, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.0703, \"times_seen\": 41.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.0068469564978321275, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.105, \"times_seen\": 3.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.0041018223527946865, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.0347, \"times_seen\": 25.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.005958138764677321, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.0627, \"times_seen\": 22.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.01041458840621071, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.3069, \"times_seen\": 24.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.03219466960969989, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.021, \"times_seen\": 9.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.006528195535170853, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.0736, \"times_seen\": 35.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.018984280773821787, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.03521321193014037, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.1119, \"times_seen\": 16.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.012787060062047157, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": -0.126, \"times_seen\": 6.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.0048524416223279365, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0507, \"times_seen\": 48.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.05897367569517278, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0925, \"times_seen\": 16.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.03275269692165812, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": -0.0987, \"times_seen\": 21.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.017076257912392402, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0129, \"times_seen\": 13.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": 0.014049380653726575, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.1346, \"times_seen\": 16.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.02859023687716847, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.1093, \"times_seen\": 11.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.012539089807922805, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0324, \"times_seen\": 18.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.03672684378776065, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.0269, \"times_seen\": 15.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.029585579332788603, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.0726, \"times_seen\": 24.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": 0.011268071319829966, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0406, \"times_seen\": 10.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.03196061529070689, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.1336, \"times_seen\": 11.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.010746993891403631, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0316, \"times_seen\": 12.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.01293604010213551, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.2905, \"times_seen\": 5.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": 0.06138066101666863, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.0354, \"times_seen\": 19.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.3973762157799502, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0017, \"times_seen\": 177.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.003366339845470603, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.005, \"times_seen\": 140.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.062343068637629395, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1365, \"times_seen\": 192.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.5930829530050945, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1601, \"times_seen\": 41.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": 0.056488869347445715, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0954, \"times_seen\": 53.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": 0.012140942091607026, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0146, \"times_seen\": 36.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": 0.13898641142252857, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1174, \"times_seen\": 59.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.0406876328466886, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0065, \"times_seen\": 29.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.15470916455155515, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0908, \"times_seen\": 113.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.05675205112503391, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0553, \"times_seen\": 37.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 0.009482775609693649, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0523, \"times_seen\": 81.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": 0.0904242058750415, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0268, \"times_seen\": 92.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": 0.003395350224220724, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1306, \"times_seen\": 24.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.1867750732884681, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": -0.1142, \"times_seen\": 145.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.1023726930711035, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0969, \"times_seen\": 255.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.12119633851958503, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0799, \"times_seen\": 89.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.06888806794929106, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0418, \"times_seen\": 159.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.02875103700546358, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1616, \"times_seen\": 39.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"Y\", \"escape\": -0.13801563076587092, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0413, \"times_seen\": 39.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": 0.009602811142407316, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": -2.6083, \"times_seen\": 4.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.0049746640095183646, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.068, \"times_seen\": 24.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.027611927730989392, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0788, \"times_seen\": 136.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.026648561900622703, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.1474, \"times_seen\": 29.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.05051707337408393, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0387, \"times_seen\": 38.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.06378060008596756, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.062, \"times_seen\": 34.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.06920360725800155, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0331, \"times_seen\": 56.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.13868551978707314, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0309, \"times_seen\": 53.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": 0.35447931846661, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0401, \"times_seen\": 87.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.6504530951111871, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0742, \"times_seen\": 206.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.06148021532637554, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.1361, \"times_seen\": 65.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.16116259009451964, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0384, \"times_seen\": 145.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.014053254760695447, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0083, \"times_seen\": 43.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.027240497466753295, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0385, \"times_seen\": 153.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.08437402577292388, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0178, \"times_seen\": 148.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": 0.47511122479607526, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0973, \"times_seen\": 24.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.31611884154565767, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0877, \"times_seen\": 134.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.005936371416913434, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0426, \"times_seen\": 190.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.0948252126936325, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0431, \"times_seen\": 93.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": -0.04763399681198369, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0581, \"times_seen\": 32.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": 0.07837439684024985, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0973, \"times_seen\": 83.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.2745078858737253, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -2.5774, \"times_seen\": 7.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.02074137482497824, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0534, \"times_seen\": 16.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": -0.05759673915065905, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0372, \"times_seen\": 19.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.009073201918902077, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0428, \"times_seen\": 17.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.0355806995327254, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.013125026425140872, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0788, \"times_seen\": 17.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.41326097874364465, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": -0.0458, \"times_seen\": 55.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.5259012721127646, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0151, \"times_seen\": 72.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.05206683165138715, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0427, \"times_seen\": 119.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.031209845694398653, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0471, \"times_seen\": 42.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": -0.02400179303943383, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0154, \"times_seen\": 16.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.08031337237477994, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.1019, \"times_seen\": 78.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.01937363875583149, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.1084, \"times_seen\": 114.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": 0.029747672954558015, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0788, \"times_seen\": 32.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.18008607715134567, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0973, \"times_seen\": 89.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.3487768985148567, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0149, \"times_seen\": 147.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.01731047045233418, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.093, \"times_seen\": 22.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.028442534312230247, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": -0.0796, \"times_seen\": 44.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": -0.042867548619133354, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.2354, \"times_seen\": 16.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.019167520415483457, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0478, \"times_seen\": 69.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.014067186340441218, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -0.0869, \"times_seen\": 28.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"W\", \"escape\": 0.004064346776711178, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -0.1149, \"times_seen\": 16.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.006981590670662429, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0759, \"times_seen\": 11.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": 0.002872154570497285, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -0.0415, \"times_seen\": 15.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.1681263512269484, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.059, \"times_seen\": 252.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": 0.2682850390094605, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0759, \"times_seen\": 60.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.08535766413757107, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0457, \"times_seen\": 82.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -0.07501190424706244, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.2209, \"times_seen\": 95.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.07212819685416041, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.1373, \"times_seen\": 192.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.3478880485073688, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0554, \"times_seen\": 193.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.028329416397520495, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0006, \"times_seen\": 57.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": 0.04970547817647454, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0778, \"times_seen\": 30.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": -0.08057561909657317, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0148, \"times_seen\": 128.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": 0.0039147495741961415, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0204, \"times_seen\": 32.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.5057708232150184, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0226, \"times_seen\": 225.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": 0.3258535860558732, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0158, \"times_seen\": 155.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.03856417606361765, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0104, \"times_seen\": 33.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.09279776363521634, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0699, \"times_seen\": 136.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.00022817411547796117, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0119, \"times_seen\": 192.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.07332091471386147, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0334, \"times_seen\": 127.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.4333527055906734, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0193, \"times_seen\": 151.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.000498427086563487, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.1933, \"times_seen\": 40.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.014793994464611979, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.079, \"times_seen\": 196.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": 0.014014086906252856, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -2.1444, \"times_seen\": 2.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": -0.010771588283295334, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0333, \"times_seen\": 29.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.08216213311729584, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.1318, \"times_seen\": 47.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.03783909494488746, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -1.455, \"times_seen\": 1.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0038743804875399908, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -1.0138, \"times_seen\": 1.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.047111421986990976, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.2249, \"times_seen\": 29.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.003821567911823901, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.1303, \"times_seen\": 15.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.042445759750856016, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.025662763938579934, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.0202, \"times_seen\": 51.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.1165289168532626, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.0555, \"times_seen\": 17.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.04652644374881804, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.0751, \"times_seen\": 11.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.005567263987521397, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.752, \"times_seen\": 2.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.18721858349992096, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.0307, \"times_seen\": 60.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.06167287891587058, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.2553, \"times_seen\": 53.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.04292227344361215, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": 0.0107, \"times_seen\": 9.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.002273594035014986, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.2198, \"times_seen\": 14.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.06593155497579277, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.1073, \"times_seen\": 16.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.023112729486308724, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.0657, \"times_seen\": 15.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.02825519031656737, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.4, \"times_seen\": 12.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.006419719455679965, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.1143, \"times_seen\": 33.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.22943530909204674, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.14, \"times_seen\": 34.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -1.942403480157734, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.051, \"times_seen\": 33.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.008431715880023, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.0638, \"times_seen\": 5.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.0565064857331163, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.0464, \"times_seen\": 13.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.045627292042035535, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": 0.2581, \"times_seen\": 24.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.008332817828115681, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.0035, \"times_seen\": 10.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.05157726085452082, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.9968, \"times_seen\": 19.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.021343808570406016, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.0575, \"times_seen\": 27.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.08016684924991001, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.1762, \"times_seen\": 21.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.025822705773227095, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.164, \"times_seen\": 98.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.03264595970968236, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.1271, \"times_seen\": 19.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.004708850436804782, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.2285, \"times_seen\": 2.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.0867876936354207, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": 0.0082, \"times_seen\": 51.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.2734094272980457, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.0122, \"times_seen\": 22.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"-\", \"escape\": 0.04475271027102374, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.4579, \"times_seen\": 22.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.024153026850396848, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.6218, \"times_seen\": 21.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.05973279178297438, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.7148, \"times_seen\": 39.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.018295391385252907, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -2.3934, \"times_seen\": 2.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.02171535271018584, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.7449, \"times_seen\": 7.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.014435081992803009, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.0766, \"times_seen\": 22.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": -0.0016663664132232025, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -3.0402, \"times_seen\": 1.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"C\", \"escape\": -0.03487509557569239, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.136, \"times_seen\": 9.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.014630891418238172, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.1528, \"times_seen\": 24.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.012688343860079818, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.0457, \"times_seen\": 23.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.011459376267068135, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.0667, \"times_seen\": 19.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.32348776022237247, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.0785, \"times_seen\": 42.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -1.7518767361256344, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.2563, \"times_seen\": 13.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.020031976239473354, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.0829, \"times_seen\": 48.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.05417852114856617, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.0264, \"times_seen\": 17.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.6803745851058758, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.1479, \"times_seen\": 24.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.020362846854131252, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -2.4263, \"times_seen\": 6.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.0069175852193956, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.1467, \"times_seen\": 17.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -1.2836428682282381, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": 0.0335, \"times_seen\": 81.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.019554334184984364, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": 0.2801, \"times_seen\": 20.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.04554274663732027, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.1553, \"times_seen\": 54.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.0033876392479579623, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.1074, \"times_seen\": 13.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.09387463651371199, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.2114, \"times_seen\": 73.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.01173103137934604, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.4421, \"times_seen\": 58.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": 0.06466187068711646, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -2.9525, \"times_seen\": 4.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.021523067086769362, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.258, \"times_seen\": 7.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.000425994974977739, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.881, \"times_seen\": 1.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.022063585974437964, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -1.9767, \"times_seen\": 8.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.009115600220531657, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.8347, \"times_seen\": 3.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": 0.008489245377038926, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.9064, \"times_seen\": 4.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.008683217912867221, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.0255, \"times_seen\": 15.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.00968607004802191, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.2364, \"times_seen\": 12.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": -0.007047685629569494, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -3.1398, \"times_seen\": 2.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.009187600325271205, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.4407, \"times_seen\": 76.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.024591565873196903, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.0555, \"times_seen\": 101.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.01699709011342845, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.183, \"times_seen\": 33.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.012609061203081553, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.0793, \"times_seen\": 12.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.00604720758114402, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -2.6703, \"times_seen\": 2.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.003413366259028278, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.9475, \"times_seen\": 2.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.039811923413615065, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -0.2771, \"times_seen\": 20.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.0015623393383086463, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -3.0231, \"times_seen\": 5.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.007069082818317187, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.8708, \"times_seen\": 1.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"T\", \"escape\": 0.012829679371974365, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -3.114, \"times_seen\": 2.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.013818547405509007, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.3614, \"times_seen\": 17.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.01699760338632065, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.1833, \"times_seen\": 15.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.04624293559520563, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.3369, \"times_seen\": 24.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.019061944214053477, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.6505, \"times_seen\": 6.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.0019627559851557374, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.2806, \"times_seen\": 12.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.020868351302181645, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.0885, \"times_seen\": 10.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.0005269789146817438, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.5236, \"times_seen\": 17.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.001680808890884782, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -2.5734, \"times_seen\": 1.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": 0.05674854568069211, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -2.5408, \"times_seen\": 5.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.025994046089062205, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.2054, \"times_seen\": 10.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.006881091174675557, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -2.4163, \"times_seen\": 2.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.045305380817349125, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.2226, \"times_seen\": 67.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.03627255359264895, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.5812, \"times_seen\": 29.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.0720781023644162, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.9631, \"times_seen\": 56.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.48155084534150777, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.0349, \"times_seen\": 73.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.016151669961290107, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.2343, \"times_seen\": 26.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.004518502339963114, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.3526, \"times_seen\": 48.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.0029988361276942358, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": 0.1911, \"times_seen\": 21.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.0063998209003188295, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.2027, \"times_seen\": 6.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.0746018031007508, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.3224, \"times_seen\": 13.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0004007215632405773, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.155, \"times_seen\": 42.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.013235837516777496, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -2.3846, \"times_seen\": 6.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.022647108645187243, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.2821, \"times_seen\": 6.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.0074216730416644325, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.0316, \"times_seen\": 29.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.012443989640466828, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.5048, \"times_seen\": 16.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"A\", \"escape\": 0.34590450960497426, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1267, \"times_seen\": 107.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"C\", \"escape\": -0.06239730052637177, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1959, \"times_seen\": 45.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"D\", \"escape\": 0.359933763033274, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"E\", \"escape\": -1.3412866101631233, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.4635, \"times_seen\": 27.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.02924044189919004, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.224, \"times_seen\": 76.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"G\", \"escape\": -0.02947248161829728, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.5816, \"times_seen\": 36.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"H\", \"escape\": -0.048381948848759786, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.2237, \"times_seen\": 50.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": -0.008888255399677485, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1445, \"times_seen\": 30.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0466687248290216, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.0639, \"times_seen\": 116.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.007604998901175039, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.0785, \"times_seen\": 50.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.5594814305809538, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.3256, \"times_seen\": 48.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"P\", \"escape\": -0.3918022194303754, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.8856, \"times_seen\": 65.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"Q\", \"escape\": 0.07596035937325377, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.2541, \"times_seen\": 19.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"R\", \"escape\": 0.060205715281035035, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1713, \"times_seen\": 73.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.10624080948829, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.112, \"times_seen\": 173.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.0007932536704658887, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1663, \"times_seen\": 146.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.000544629953637428, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": 0.1071, \"times_seen\": 81.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"W\", \"escape\": 0.04875204843395118, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1706, \"times_seen\": 20.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": 0.007501205365453134, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.2847, \"times_seen\": 33.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"*\", \"escape\": -0.007667654161167029, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -3.0486, \"times_seen\": 3.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.371228466561571, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.0316, \"times_seen\": 46.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.1711551712629035, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.0467, \"times_seen\": 99.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.030368313595352928, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.1099, \"times_seen\": 9.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.06855983456107954, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3729, \"times_seen\": 43.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"L\", \"escape\": 0.00039609272792242987, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3496, \"times_seen\": 18.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"P\", \"escape\": -0.023855814666294783, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.5903, \"times_seen\": 11.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.00703747196563901, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.0732, \"times_seen\": 58.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.03857811466963436, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3448, \"times_seen\": 69.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"Y\", \"escape\": 0.037443611772876174, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3054, \"times_seen\": 13.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.003911900024641851, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -2.3838, \"times_seen\": 1.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.0428441182680622, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0891, \"times_seen\": 71.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.011998923944692999, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": -0.124, \"times_seen\": 10.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.31906965332570775, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0141, \"times_seen\": 20.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.062287736047596215, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0086, \"times_seen\": 76.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.01735693797907689, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0609, \"times_seen\": 23.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.2182426514749558, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0146, \"times_seen\": 65.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 1.8435470355481562, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.2037, \"times_seen\": 7.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.08723472398579689, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0308, \"times_seen\": 172.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0856786416070074, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.1456, \"times_seen\": 77.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -0.06880940311332781, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0324, \"times_seen\": 60.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.029235732403499054, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0439, \"times_seen\": 46.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.033068447044225846, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.1165, \"times_seen\": 204.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.1136370967698182, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0492, \"times_seen\": 122.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.12112295291212478, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0515, \"times_seen\": 88.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.1650130713744012, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0559, \"times_seen\": 133.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.15345618500196037, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0309, \"times_seen\": 59.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.18031278819488597, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0364, \"times_seen\": 168.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.393413749694892, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0211, \"times_seen\": 43.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.07009010764572253, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.074, \"times_seen\": 150.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.011621902849685447, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.1268, \"times_seen\": 162.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.04832179861053908, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0761, \"times_seen\": 70.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.3192821424903303, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0237, \"times_seen\": 304.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.051505757182060644, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0523, \"times_seen\": 182.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.0907480144320245, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0558, \"times_seen\": 130.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.02880198453686463, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.083, \"times_seen\": 60.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.0325206651967019, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.001, \"times_seen\": 111.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": 0.08776150789238249, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -2.5427, \"times_seen\": 6.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.11609739505938636, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0318, \"times_seen\": 88.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0008904890258642112, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.3138, \"times_seen\": 1.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.2625281263543154, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": 0.0587, \"times_seen\": 54.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.0416792719591627, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0383, \"times_seen\": 94.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.011626247551947513, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0293, \"times_seen\": 39.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.08375341364268606, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0632, \"times_seen\": 47.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"H\", \"escape\": -0.06486665013910131, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0559, \"times_seen\": 57.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": 0.012617147122440508, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.1329, \"times_seen\": 25.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.0037893431872380607, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.0736, \"times_seen\": 64.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.021726891307850292, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.031, \"times_seen\": 28.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"R\", \"escape\": 0.0010183276002433904, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.185, \"times_seen\": 23.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.003947424157598657, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.1495, \"times_seen\": 1.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.03546437162145294, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0456, \"times_seen\": 125.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.11819481381997585, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0125, \"times_seen\": 75.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.0030072112451995873, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.4301, \"times_seen\": 1.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.08317723195318845, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.0312, \"times_seen\": 14.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.03687431629491733, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.0773, \"times_seen\": 19.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.1205644062771098, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.134, \"times_seen\": 38.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.006555406300578514, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.1162, \"times_seen\": 1.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.0030601619723572846, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.0282, \"times_seen\": 88.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.3505057418095548, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.0332, \"times_seen\": 42.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"A\", \"escape\": -0.008381087939067746, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.3679, \"times_seen\": 10.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.003906751233201666, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0811, \"times_seen\": 72.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.03205946556678935, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0793, \"times_seen\": 77.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.30364932048911353, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": -0.0588, \"times_seen\": 85.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.009918428315648853, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.1373, \"times_seen\": 5.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.04787709589474921, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0496, \"times_seen\": 74.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.0004173322840323805, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0622, \"times_seen\": 21.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.03874770532999669, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.257, \"times_seen\": 28.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.02577366292632871, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -2.2717, \"times_seen\": 3.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": 0.16162046902736843, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.2139, \"times_seen\": 21.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -1.1899994031773113, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.7102, \"times_seen\": 11.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.07114135279895474, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -0.5601, \"times_seen\": 31.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.003654412324195581, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -1.8512, \"times_seen\": 2.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": -0.08980219164978269, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -0.187, \"times_seen\": 24.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"G\", \"escape\": -0.002856317933935481, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -1.3353, \"times_seen\": 9.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": 0.8799286315212967, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -0.3178, \"times_seen\": 35.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.0003598013462706864, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -2.3409, \"times_seen\": 5.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"S\", \"escape\": 0.03306301346787704, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -1.9068, \"times_seen\": 8.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": 0.02009764788434936, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -2.5166, \"times_seen\": 3.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.01993777449327631, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.35, \"times_seen\": 23.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.12413454661053121, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.1699, \"times_seen\": 44.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 1.1541161239673403, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.5794, \"times_seen\": 5.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.0019361549231115363, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": 0.1526, \"times_seen\": 1.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.009826684686299839, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.1673, \"times_seen\": 106.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.021449109234267457, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.0713, \"times_seen\": 54.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.007038116296112489, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.1562, \"times_seen\": 27.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.038579461966700715, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -1.1841, \"times_seen\": 28.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.013920802628493375, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -0.2396, \"times_seen\": 57.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.06071698697015826, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -1.1602, \"times_seen\": 22.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.2820100334122968, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -0.067, \"times_seen\": 45.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.03397256196687228, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.0577, \"times_seen\": 11.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.01809549515103944, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.5776, \"times_seen\": 3.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.022033630389167728, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -1.6558, \"times_seen\": 9.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.02612089655317533, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.156, \"times_seen\": 10.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.021986683420881923, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -1.5646, \"times_seen\": 4.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -1.19822149921765, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.9922, \"times_seen\": 5.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.015719776204170612, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.0697, \"times_seen\": 42.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": 0.010858366562520849, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.4085, \"times_seen\": 4.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.0009508457618754375, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -2.001, \"times_seen\": 1.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.3429134931332154, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.3128, \"times_seen\": 90.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.0018362929567960805, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.2263, \"times_seen\": 4.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.09341160769352534, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": 0.3447, \"times_seen\": 47.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.01546860691772526, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": 0.152, \"times_seen\": 31.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.0029067016329025527, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.7745, \"times_seen\": 7.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.22657094578091602, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.0787, \"times_seen\": 44.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -1.3757003660001081, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -1.0708, \"times_seen\": 45.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.04015499521964735, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.2012, \"times_seen\": 14.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.014779944680517897, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.2797, \"times_seen\": 2.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -1.726327144173522, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.137, \"times_seen\": 39.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.017942905694164044, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.5204, \"times_seen\": 7.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.03487254949681368, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": 0.1497, \"times_seen\": 8.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.00054643628836192, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": 0.1351, \"times_seen\": 8.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.016938292128680785, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.373, \"times_seen\": 17.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -1.253665594772983, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.0224, \"times_seen\": 17.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.03704787704259902, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -1.5686, \"times_seen\": 8.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.7918516914034899, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.6082, \"times_seen\": 61.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.03202894017991114, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.4187, \"times_seen\": 13.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.032124049891775586, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.2564, \"times_seen\": 38.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.16956648266800692, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.2263, \"times_seen\": 77.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.14936961685092817, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.2835, \"times_seen\": 160.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.02448609267369527, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -1.4678, \"times_seen\": 13.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.04502402649683475, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.0352, \"times_seen\": 122.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": 0.015584621296074325, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -1.9815, \"times_seen\": 12.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": 0.1172537118352689, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.1555, \"times_seen\": 16.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.0019480249790180234, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.9627, \"times_seen\": 4.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.1847513582840417, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.1061, \"times_seen\": 30.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.49542124158430395, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0792, \"times_seen\": 51.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.008288885192740134, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.1917, \"times_seen\": 2.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": -0.006264471292596614, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.014522248407395421, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.2182, \"times_seen\": 7.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.018765597441873432, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0034, \"times_seen\": 23.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -2.444444095644365, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.126, \"times_seen\": 61.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.05683004148882639, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0271, \"times_seen\": 41.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.01548685509179454, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0242, \"times_seen\": 59.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.009757551592475199, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.2199, \"times_seen\": 113.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.05086243175629038, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0148, \"times_seen\": 20.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.05566129271313482, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0657, \"times_seen\": 25.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.07058225333667018, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.069, \"times_seen\": 39.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.035378118008326465, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.4226, \"times_seen\": 39.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.006155737419360653, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.2109, \"times_seen\": 30.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.044728803914712754, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.2066, \"times_seen\": 55.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 0.010839377645651807, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.0809, \"times_seen\": 8.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.03628095918423704, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.3784, \"times_seen\": 24.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.05155233532179732, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": 0.0556, \"times_seen\": 60.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.02922303510773282, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.0779, \"times_seen\": 12.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.005109772580546417, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": 0.0329, \"times_seen\": 8.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.05742034292795934, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -0.3857, \"times_seen\": 8.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.03480687228586602, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -2.572, \"times_seen\": 4.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.006254993395138932, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -1.8954, \"times_seen\": 2.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.00896097006436738, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -1.9387, \"times_seen\": 4.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.012897600700755884, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": 0.1233, \"times_seen\": 11.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.023328930535029786, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.04005913566777436, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -1.5896, \"times_seen\": 12.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.015766477421486524, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -0.535, \"times_seen\": 10.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.006808329507004601, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -0.6093, \"times_seen\": 18.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.008567908411368598, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -1.4123, \"times_seen\": 17.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": 0.01108570781885496, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -0.7012, \"times_seen\": 3.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.005305440347960381, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -2.592, \"times_seen\": 2.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.014551048115472002, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.002422907642673006, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.1498, \"times_seen\": 1.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.007522375505358172, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.2258, \"times_seen\": 2.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.0028237608967505794, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -3.132, \"times_seen\": 1.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.01628437746351852, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.842, \"times_seen\": 2.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.01367039510678156, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -0.4963, \"times_seen\": 9.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.0025905612609740396, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": 0.0261, \"times_seen\": 9.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.005299977419320796, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.02068017307710307, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -2.7012, \"times_seen\": 2.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0003241649413006887, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.010825583312664826, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -1.1639, \"times_seen\": 5.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.009531250838504214, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -1.6211, \"times_seen\": 4.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.042758965751761045, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.2045, \"times_seen\": 40.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.23897401079550298, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.0168, \"times_seen\": 75.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.04544012015987938, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.0479, \"times_seen\": 32.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 1.0141930981522354, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.0866, \"times_seen\": 12.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.016830751383686254, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -0.0081, \"times_seen\": 16.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.005452798235735587, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -1.8059, \"times_seen\": 1.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.15271678830239127, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -0.2743, \"times_seen\": 33.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.00677607483146509, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -2.9694, \"times_seen\": 2.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.32703478451983103, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.2152, \"times_seen\": 10.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.16571093337022924, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0109, \"times_seen\": 45.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.10014199860455811, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0259, \"times_seen\": 63.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.015458613124579081, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0043, \"times_seen\": 28.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.0005733079415851984, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0183, \"times_seen\": 7.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.0008335853674870389, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -2.935, \"times_seen\": 1.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.007393079420391583, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": 0.0972, \"times_seen\": 10.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0151792573962055, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.5188, \"times_seen\": 9.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.19740590020399884, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.6765, \"times_seen\": 19.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.02945929712077333, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.1782, \"times_seen\": 49.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 1.1006496381093969, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.2585, \"times_seen\": 15.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": 0.00042341904381033727, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -1.5307, \"times_seen\": 3.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.014886703531299755, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.1638, \"times_seen\": 23.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.029136384372128798, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.2587, \"times_seen\": 15.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.003219873735579453, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.2652, \"times_seen\": 16.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.009380433496303124, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.1114, \"times_seen\": 9.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.0004820351051983624, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -2.2739, \"times_seen\": 6.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.06919923426003516, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.0998, \"times_seen\": 19.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.005995702264349916, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.2161, \"times_seen\": 1.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.005098936823120611, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.112, \"times_seen\": 3.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.007017453396758615, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.0756, \"times_seen\": 1.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.9160097111153516, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": 0.0374, \"times_seen\": 30.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.057170648892903665, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.2843, \"times_seen\": 47.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.010418814046724886, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.024, \"times_seen\": 84.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": -0.020557235027398525, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -2.2622, \"times_seen\": 1.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.011258306580089085, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.1718, \"times_seen\": 7.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.0442847256456143, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.3737, \"times_seen\": 54.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.006921811731458919, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.3962, \"times_seen\": 10.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.0004722544012961853, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.439, \"times_seen\": 11.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.0034115964631693213, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.0765, \"times_seen\": 14.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": 0.06054011678814495, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -1.2814, \"times_seen\": 6.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.009103250411743395, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.0348, \"times_seen\": 4.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": 0.0009592052250526446, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.0677, \"times_seen\": 1.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.02193792863078809, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.1177, \"times_seen\": 6.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.0019495780434006628, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -1.3304, \"times_seen\": 1.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.005592013369886881, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.0595, \"times_seen\": 6.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.01217295642388329, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.0223, \"times_seen\": 8.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.3639974727435516, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.1075, \"times_seen\": 15.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.013445975444644478, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.1681, \"times_seen\": 11.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.00025504495272862397, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.3921, \"times_seen\": 1.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": 0.005812541509681066, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -2.1196, \"times_seen\": 6.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.003799150982660506, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.0382, \"times_seen\": 18.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.004450619278456671, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.1827, \"times_seen\": 1.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.7096754859032776, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.2101, \"times_seen\": 61.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.004992488467960239, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.5421, \"times_seen\": 1.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.035699292651961645, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.219, \"times_seen\": 27.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.05358310418829845, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.3493, \"times_seen\": 32.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.03648133865555449, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.0396, \"times_seen\": 13.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.01687061368082017, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.041355588862298336, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.4349, \"times_seen\": 11.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.019892794107567512, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.4226, \"times_seen\": 7.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.026123744791991404, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.106, \"times_seen\": 35.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.010385582808208945, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.2638, \"times_seen\": 12.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.0207789292728053, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.2409, \"times_seen\": 12.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.025119085622757095, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.4791, \"times_seen\": 18.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.007645750181419656, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.3778, \"times_seen\": 3.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.019622206139770518, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": 0.0844, \"times_seen\": 32.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.005598556843331243, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -2.3119, \"times_seen\": 2.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.013188281398299074, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.3373, \"times_seen\": 3.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.008376329951828682, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.08396476098956977, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.1653391185434116, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.0909, \"times_seen\": 50.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.015017410646052179, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.2494, \"times_seen\": 9.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.010847423538514136, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.4587, \"times_seen\": 16.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.010867872273670393, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.4335, \"times_seen\": 29.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.04295624483398182, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.2335, \"times_seen\": 10.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.000326870525833967, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.1666, \"times_seen\": 23.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.017252057136948183, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.4105, \"times_seen\": 7.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.013490946331953909, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.8318, \"times_seen\": 10.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.019021618759153952, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.3397, \"times_seen\": 9.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.003470079238608833, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.8472, \"times_seen\": 1.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": 0.01562714111098406, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.2664, \"times_seen\": 2.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": -0.006782868964079606, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -1.8136, \"times_seen\": 3.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.015041904753218097, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.3392, \"times_seen\": 2.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.04282845561041361, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.0898, \"times_seen\": 42.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.09412032995311218, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -0.0837, \"times_seen\": 81.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.012038202498899137, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -0.2183, \"times_seen\": 15.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.11033924744820901, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.3539, \"times_seen\": 41.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": 0.011481787862926663, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -0.1598, \"times_seen\": 9.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.10587594347902783, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.2681, \"times_seen\": 59.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.02413190857878245, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.3141, \"times_seen\": 16.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.0016539517992195541, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -0.1434, \"times_seen\": 24.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.04659002577912409, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -0.2888, \"times_seen\": 16.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.02116985069700585, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -1.5164, \"times_seen\": 8.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.1249050687589067, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -0.1178, \"times_seen\": 18.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.1460589282243436, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": 0.125, \"times_seen\": 41.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.2662683216500119, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0731, \"times_seen\": 137.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.07407001620478706, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0553, \"times_seen\": 29.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.008076684395520516, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.1193, \"times_seen\": 144.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": -0.07761112923781, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": 0.0087, \"times_seen\": 9.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.032952355130751905, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0991, \"times_seen\": 47.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": -0.026013603303003566, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0935, \"times_seen\": 10.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.004619126241442877, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -2.8438, \"times_seen\": 1.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.049457883349507965, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.0108, \"times_seen\": 37.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.027915285727484206, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.0847, \"times_seen\": 42.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.01679016349842688, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.3028, \"times_seen\": 4.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.03540662528868687, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.068, \"times_seen\": 12.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.07228283043208857, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.0252, \"times_seen\": 26.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.053138723693429465, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0199, \"times_seen\": 87.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": 0.022670731683340606, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.1983, \"times_seen\": 13.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.8770714151740271, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0987, \"times_seen\": 16.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.022191615806278518, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0854, \"times_seen\": 15.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.03464771706537786, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.2441, \"times_seen\": 16.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": -0.003878915266485381, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.1774, \"times_seen\": 6.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": -0.019172645946348085, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.04203145492970857, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0384, \"times_seen\": 43.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": 0.04645879746134275, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.1883, \"times_seen\": 17.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.034953828744487464, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.2205, \"times_seen\": 24.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.05998772449108189, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.0149, \"times_seen\": 18.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.02022591029068138, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.073, \"times_seen\": 13.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.0004897314707807371, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.0814, \"times_seen\": 13.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -4.603374897488893, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.0079, \"times_seen\": 28.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.017549688454541284, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.2271, \"times_seen\": 9.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.04732350097497235, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.0102, \"times_seen\": 26.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": 0.0038713187376064294, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.1167, \"times_seen\": 7.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.5786036457627466, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0073, \"times_seen\": 185.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.05007753190920134, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.1698, \"times_seen\": 32.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.05109982990789065, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0292, \"times_seen\": 71.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": 0.05433955540089442, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0714, \"times_seen\": 35.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.19597251362193807, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0135, \"times_seen\": 127.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.38865404853061525, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0006, \"times_seen\": 106.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.056877382811542754, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0646, \"times_seen\": 50.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -0.0273246509996982, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0658, \"times_seen\": 32.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.7897644206542807, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0911, \"times_seen\": 81.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.08202053788428955, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0307, \"times_seen\": 23.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.00881617978767599, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0782, \"times_seen\": 125.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": 0.4613361170413606, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0112, \"times_seen\": 104.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": -0.0448854150089959, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.099, \"times_seen\": 39.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.7751876000164083, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.1031, \"times_seen\": 85.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.0253378527879328, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0089, \"times_seen\": 115.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.011145867990408443, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0597, \"times_seen\": 94.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.006116021515383238, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0432, \"times_seen\": 76.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": 0.10007419016634267, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0004, \"times_seen\": 22.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.17806190004577385, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.1254, \"times_seen\": 108.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": -0.0003386688826176483, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -2.988, \"times_seen\": 1.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": -0.003717565212790395, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0355, \"times_seen\": 2.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.007166731190657681, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": 0.1536, \"times_seen\": 2.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 0.002000997273954745, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.1663, \"times_seen\": 14.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.8354445307281732, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.0056, \"times_seen\": 52.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.011485575234747174, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.0651, \"times_seen\": 13.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.025924491672451398, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.0358, \"times_seen\": 34.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.021027155873880272, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.1179, \"times_seen\": 16.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"-\", \"escape\": -0.008992747256468741, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": 0.0539, \"times_seen\": 7.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.0117283640907826, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.024508669442038694, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": -0.0353, \"times_seen\": 20.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.029337733119431917, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": -0.0265, \"times_seen\": 28.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.03945684235442238, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": -0.134, \"times_seen\": 10.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.019865097766475215, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.2253, \"times_seen\": 3.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.02882949812279627, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.0353, \"times_seen\": 32.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": -0.041783269312407216, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.0078, \"times_seen\": 34.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.000367431317995936, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.1315, \"times_seen\": 42.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0016755805132731194, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.191, \"times_seen\": 11.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.022159554963356358, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.1949, \"times_seen\": 25.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.014896887010363357, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.144, \"times_seen\": 27.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0070500963169542585, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.1531, \"times_seen\": 4.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.007189980584954292, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.2015, \"times_seen\": 2.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.01503755614256007, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.0782, \"times_seen\": 10.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.148457496505315, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.0493, \"times_seen\": 16.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": -0.007743964627840727, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.2301, \"times_seen\": 15.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": 0.026510661884477055, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.0929, \"times_seen\": 18.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.11616883498007055, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0645, \"times_seen\": 145.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.15942397203755868, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1518, \"times_seen\": 140.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.253515181417122, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0027, \"times_seen\": 66.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -0.008784621657722052, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0629, \"times_seen\": 32.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.4388744160817454, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1234, \"times_seen\": 121.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.04343720297620907, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1008, \"times_seen\": 77.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.020938452553129688, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0047, \"times_seen\": 50.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": 0.08142316071270236, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.3408, \"times_seen\": 40.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": -0.4381470001599373, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0144, \"times_seen\": 134.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.014084845122114659, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0018, \"times_seen\": 49.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.004869802879815939, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0348, \"times_seen\": 83.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": 0.40737230051598505, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0264, \"times_seen\": 131.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": -0.31818873312195045, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0365, \"times_seen\": 41.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": 0.2643764576742453, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.3689, \"times_seen\": 113.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.013176079175542862, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1074, \"times_seen\": 207.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.21832004907276706, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0065, \"times_seen\": 93.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.43328239382820927, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0163, \"times_seen\": 89.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": 0.09310628194536494, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0605, \"times_seen\": 32.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.011925835930982571, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1328, \"times_seen\": 82.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": 0.013508111907834613, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0809, \"times_seen\": 14.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": -0.1444147088809089, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.168, \"times_seen\": 10.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"K\", \"escape\": -0.004134708641953208, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.1113, \"times_seen\": 14.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": -0.011947144272809738, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0101, \"times_seen\": 33.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.012072998904689164, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0471, \"times_seen\": 80.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": 0.02090603490420219, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.1253, \"times_seen\": 19.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": -0.00936059490108322, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.0047, \"times_seen\": 46.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.031514256091604485, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.0445, \"times_seen\": 11.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": 0.015681406096771846, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0282, \"times_seen\": 8.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"T\", \"escape\": 0.11831731239491682, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.06, \"times_seen\": 15.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.009910371111461445, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0143, \"times_seen\": 87.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"-\", \"escape\": -0.007511640686806955, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0301, \"times_seen\": 14.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": -9.096697025113719e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0112, \"times_seen\": 1.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.3249580097898102, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0494, \"times_seen\": 76.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.050182805425181005, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0829, \"times_seen\": 21.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.014289089976536988, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.2134, \"times_seen\": 5.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.09734200655352297, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0867, \"times_seen\": 79.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": -0.012312880916938164, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.1616, \"times_seen\": 4.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.0023080506461820066, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -0.0244, \"times_seen\": 39.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.011162302698723736, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0635, \"times_seen\": 62.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.029383058025239175, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -0.0491, \"times_seen\": 11.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.06282879008552177, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0116, \"times_seen\": 62.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.08075058075769377, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.0741, \"times_seen\": 21.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.0396655493644192, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.1002, \"times_seen\": 46.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": 0.03898078196214049, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.0122, \"times_seen\": 17.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.25032985856117274, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0886, \"times_seen\": 75.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.005500150961871608, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0449, \"times_seen\": 108.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.10151604917480155, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0044, \"times_seen\": 52.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": 0.00990439728476673, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.0551, \"times_seen\": 17.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.00126455660790487, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.0678, \"times_seen\": 14.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.0028656718854046873, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0107, \"times_seen\": 26.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.049604407360390804, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.1116, \"times_seen\": 25.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.002146189050301167, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0619, \"times_seen\": 11.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.026372387191157587, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.1299, \"times_seen\": 13.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.01907245206124803, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0286, \"times_seen\": 21.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.023068351419018453, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0276, \"times_seen\": 16.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.03906740131180603, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.0154, \"times_seen\": 23.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.015210134031563256, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0949, \"times_seen\": 50.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.044742329558798005, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0173, \"times_seen\": 53.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.07433885136385042, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0648, \"times_seen\": 66.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.020129883103501098, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.1539, \"times_seen\": 11.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.02843636249752533, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0102, \"times_seen\": 23.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.00858290743865454, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0316, \"times_seen\": 23.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.0003355574651557521, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": -0.1884, \"times_seen\": 11.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": 0.008340462375008977, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.1374, \"times_seen\": 33.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.07965457781493064, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.3201, \"times_seen\": 14.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.002478864931572861, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.7801, \"times_seen\": 1.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.010851393993583444, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.1226, \"times_seen\": 28.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.046989257328938265, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.2093, \"times_seen\": 34.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.012564675996778284, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.205, \"times_seen\": 6.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.7506982126807465, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.0894, \"times_seen\": 44.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.011528999373098191, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.3216, \"times_seen\": 4.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.022881154748549567, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.0198, \"times_seen\": 6.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.01749127224746309, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.1366, \"times_seen\": 9.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.039170458482807084, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.0105, \"times_seen\": 51.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.008921149466525804, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.2935, \"times_seen\": 9.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.01819471434236482, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 0.005623394822757926, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.1256, \"times_seen\": 13.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.0193108703563896, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.1035, \"times_seen\": 58.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": 0.0026342452563227503, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.2968, \"times_seen\": 8.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"G\", \"escape\": 0.07362375408751433, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.056, \"times_seen\": 16.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"K\", \"escape\": -0.021563935826976393, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.1747, \"times_seen\": 15.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": -0.021168296273718263, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.0578, \"times_seen\": 68.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": 0.5323330175582931, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.0097, \"times_seen\": 66.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"S\", \"escape\": 0.14860353883662555, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.0447, \"times_seen\": 47.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"Y\", \"escape\": 0.003506169752189066, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": 0.3474959148877513, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -2.6709, \"times_seen\": 6.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"-\", \"escape\": -0.01047478738558993, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.1988, \"times_seen\": 6.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -0.14370640782839045, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0462, \"times_seen\": 82.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"K\", \"escape\": 0.011679728398063598, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": -0.2152, \"times_seen\": 13.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": 0.025751357385033796, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0377, \"times_seen\": 60.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"R\", \"escape\": -0.008939011620444848, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0217, \"times_seen\": 15.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.057397200689812564, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": -0.3661246208548844, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0424, \"times_seen\": 41.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"W\", \"escape\": 0.030013340526321795, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.1417, \"times_seen\": 11.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"-\", \"escape\": -0.016024389524873128, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": -0.0214, \"times_seen\": 13.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.5906588930387314, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0613, \"times_seen\": 38.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.00016044061788817422, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0981, \"times_seen\": 17.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.011487498856720159, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.1528, \"times_seen\": 52.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.041985687274488065, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.1484, \"times_seen\": 73.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.02146151950345173, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.0372, \"times_seen\": 72.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": 0.001018610621877398, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.1094, \"times_seen\": 14.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.047794273117322296, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0753, \"times_seen\": 14.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"-\", \"escape\": -0.07414326326531936, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.0626, \"times_seen\": 31.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.0055699919989714245, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.0684, \"times_seen\": 19.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.03594500732899993, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.1026, \"times_seen\": 54.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.0007356668047127427, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.0315, \"times_seen\": 19.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.09951589804824909, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.1457, \"times_seen\": 39.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.005584147153878404, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.4192, \"times_seen\": 7.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.012583220310274743, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.025, \"times_seen\": 24.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.020063781574869093, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.2218, \"times_seen\": 8.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.19505394253247124, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.1881, \"times_seen\": 11.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.012675758080685882, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.183, \"times_seen\": 10.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.006586116671096871, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.0872, \"times_seen\": 18.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.010426770569152656, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.2672, \"times_seen\": 13.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.27005309219492896, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.0483, \"times_seen\": 64.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.01615633181562491, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.1704, \"times_seen\": 25.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.021681905506158956, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.011, \"times_seen\": 27.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.02034944613118532, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.0518, \"times_seen\": 39.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.0792011498822219, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.0439, \"times_seen\": 27.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.00654144304569439, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -2.2596, \"times_seen\": 1.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"-\", \"escape\": 0.031052201338542373, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.348, \"times_seen\": 25.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"A\", \"escape\": 0.137097697310283, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0147, \"times_seen\": 109.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.02805414034880805, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0333, \"times_seen\": 96.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"D\", \"escape\": -0.01575639336905866, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0643, \"times_seen\": 47.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"E\", \"escape\": -0.016038095533731183, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.1051, \"times_seen\": 6.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"G\", \"escape\": -0.137435427061612, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0596, \"times_seen\": 71.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"H\", \"escape\": 0.06981180531636115, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.1837, \"times_seen\": 76.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.24031152574508355, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0831, \"times_seen\": 84.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"K\", \"escape\": 0.06577010708382909, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.1089, \"times_seen\": 26.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.06970776704566001, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0042, \"times_seen\": 226.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"M\", \"escape\": -0.045600153973658776, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.1247, \"times_seen\": 27.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"N\", \"escape\": 0.6507414743818369, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.06, \"times_seen\": 53.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"P\", \"escape\": -0.14497761406818455, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0087, \"times_seen\": 136.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"Q\", \"escape\": 0.004965947482118815, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0048, \"times_seen\": 49.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"R\", \"escape\": 0.0013659297192046525, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0804, \"times_seen\": 106.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.03754910432045564, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0097, \"times_seen\": 255.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"T\", \"escape\": -0.4529426216499103, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0486, \"times_seen\": 93.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.08699034705096399, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.01, \"times_seen\": 83.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"W\", \"escape\": -0.025663884928472394, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.1925, \"times_seen\": 31.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.2264075875240483, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0065, \"times_seen\": 94.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"*\", \"escape\": -0.004902357317743752, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -2.1956, \"times_seen\": 3.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": -0.06224975796629257, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0351, \"times_seen\": 24.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.420734605941759, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.075, \"times_seen\": 54.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.05489289696944895, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.1199, \"times_seen\": 64.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.002524855501486362, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.0516, \"times_seen\": 28.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.010110712503875054, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.0289, \"times_seen\": 19.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.7258523241572542, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.1885, \"times_seen\": 23.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.3187727881695361, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.086, \"times_seen\": 65.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.14497081458723318, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.044, \"times_seen\": 18.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": -0.008292445015642207, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": -0.1961, \"times_seen\": 29.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.03547081890070332, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.1293, \"times_seen\": 32.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.09543749990599952, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0272, \"times_seen\": 44.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.7173867498623097, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0127, \"times_seen\": 41.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.01233960884857807, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": 0.1168, \"times_seen\": 16.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": 0.014667940008249978, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0122, \"times_seen\": 1.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": 0.009253357872946793, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": 0.128, \"times_seen\": 20.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.03107987332352832, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.3634, \"times_seen\": 24.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.0589381659545561, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.0013, \"times_seen\": 18.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.009015733760810158, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.025, \"times_seen\": 66.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.0032573582669232046, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.1281, \"times_seen\": 22.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.0085728470328696, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.5272, \"times_seen\": 3.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"V\", \"escape\": 0.022531585083104835, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.4175, \"times_seen\": 8.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.0030561603558839565, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -2.7036, \"times_seen\": 1.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"-\", \"escape\": -0.036806489052699426, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.2207, \"times_seen\": 21.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.03300585141214504, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.1208, \"times_seen\": 13.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.06688820516935291, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.0904, \"times_seen\": 94.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.042937220039547155, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.011282214327262792, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.0846, \"times_seen\": 10.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.014193415524233765, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.1456, \"times_seen\": 32.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.13287701143818226, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.066, \"times_seen\": 26.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 0.01772478399947534, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.0075, \"times_seen\": 19.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.010789050359327462, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.1564, \"times_seen\": 9.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.04689919682920909, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.1405, \"times_seen\": 15.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.02995436420612909, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.0007, \"times_seen\": 89.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.20782549789300914, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.2646, \"times_seen\": 18.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.2450438906624222, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.0073, \"times_seen\": 65.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.02820589604150585, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.2622, \"times_seen\": 12.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.04541551397826886, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.008, \"times_seen\": 11.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.00923620850319916, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.0481, \"times_seen\": 19.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.006152207071515633, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.0921, \"times_seen\": 5.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 0.220848326131958, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.1466, \"times_seen\": 26.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.002541584973661388, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.033, \"times_seen\": 3.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.006919693859240775, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.2321, \"times_seen\": 17.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.02271083113909523, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.047, \"times_seen\": 27.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": 0.2210642651924555, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": -0.0315, \"times_seen\": 18.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.05740871898409374, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.099, \"times_seen\": 12.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.0022023729758694228, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.2722, \"times_seen\": 1.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 0.005556790932016957, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.09729687192017461, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0681, \"times_seen\": 116.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.04020123444056505, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0047, \"times_seen\": 96.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.03504021843847422, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0087, \"times_seen\": 82.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": 0.0038935040936574233, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0687, \"times_seen\": 20.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.003932391901533254, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.0898, \"times_seen\": 17.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.143157770138994, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": 0.014, \"times_seen\": 51.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.007768304434928098, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.2323, \"times_seen\": 16.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.08032995666039296, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1011, \"times_seen\": 19.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.06485644401447513, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1513, \"times_seen\": 28.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.043200259603126144, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1756, \"times_seen\": 70.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.030185709197238578, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1064, \"times_seen\": 22.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": 0.014960628689016448, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1313, \"times_seen\": 35.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.02347960249723535, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.6996, \"times_seen\": 14.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.001601750812222593, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": 0.1748, \"times_seen\": 1.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.029294445344232253, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.3027, \"times_seen\": 16.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.001215705138542608, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.591, \"times_seen\": 5.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.0483046108943213, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.311, \"times_seen\": 12.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.03345018631971136, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": 0.0485, \"times_seen\": 23.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.044956257126822705, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.5794, \"times_seen\": 10.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"A\", \"escape\": -0.003430262291047297, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.1822, \"times_seen\": 1.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.002718499915631365, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.5685, \"times_seen\": 1.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.0021823602049822716, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.8823, \"times_seen\": 2.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.01217060439328619, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.9128, \"times_seen\": 6.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.0074495188153647016, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.5698, \"times_seen\": 5.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": 0.018069372217215558, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.8512, \"times_seen\": 3.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.07281762897719449, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.2336, \"times_seen\": 8.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.014087969476177941, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.4323, \"times_seen\": 7.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.01347810428757768, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.6835, \"times_seen\": 45.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.024304075340996784, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.708, \"times_seen\": 11.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.7872223119700053, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": 0.0177, \"times_seen\": 71.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.19929358505216097, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.0554, \"times_seen\": 11.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.022972281699184763, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -1.1296, \"times_seen\": 11.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"A\", \"escape\": 0.47093863544087416, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.4464, \"times_seen\": 19.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.005362597098729797, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.3046, \"times_seen\": 5.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.226257932456505, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.0966, \"times_seen\": 62.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.07188684481679429, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.5267, \"times_seen\": 9.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.014511714513523137, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": 0.0364, \"times_seen\": 2.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": 0.05632723996565816, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.4392, \"times_seen\": 23.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.04333376591731347, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": 0.0394, \"times_seen\": 29.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.01182576900061184, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.515, \"times_seen\": 3.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.1324101846481678, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.4174, \"times_seen\": 92.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": -0.03489258715694739, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": 0.0342, \"times_seen\": 19.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.040894633337980976, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.3936, \"times_seen\": 11.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.009626207320270823, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.3211, \"times_seen\": 15.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"-\", \"escape\": 0.019547480052327988, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -1.1936, \"times_seen\": 6.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.017494434929578296, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.7147, \"times_seen\": 14.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.012134496789714818, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.0061, \"times_seen\": 20.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.1265065605446351, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.059, \"times_seen\": 60.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.005079626196666856, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.2233, \"times_seen\": 7.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"M\", \"escape\": 0.011179124343412174, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.1524, \"times_seen\": 7.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.023601202414742818, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.7647, \"times_seen\": 4.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.003033393327503864, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -1.4378, \"times_seen\": 1.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"-\", \"escape\": -0.002427113769296041, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.3881, \"times_seen\": 16.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.02639567243845447, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.1624, \"times_seen\": 47.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.008403617713918022, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.6295, \"times_seen\": 13.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.012346992320708516, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0418, \"times_seen\": 4.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.007139049087669425, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0087, \"times_seen\": 34.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.03506790598856992, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0754, \"times_seen\": 48.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.029381681063000212, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.14, \"times_seen\": 37.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.0057640841611569064, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.0036, \"times_seen\": 14.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.008591761445219188, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.1799, \"times_seen\": 5.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.044927175944518276, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.2477, \"times_seen\": 18.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.025598835692162477, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.0799, \"times_seen\": 6.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0033816825638297086, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -1.1398, \"times_seen\": 1.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.012640155427907536, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.1085, \"times_seen\": 28.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.0036330712937231815, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.1978, \"times_seen\": 7.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.004863568739686678, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.5557, \"times_seen\": 3.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.10920034966617313, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.1065, \"times_seen\": 6.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0446985575880228, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.0688, \"times_seen\": 32.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.009849431223547025, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.2875, \"times_seen\": 3.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.019979227937632325, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.0488, \"times_seen\": 23.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.008955513461297136, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.3347, \"times_seen\": 14.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"D\", \"escape\": -0.010462708202140621, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -0.1765, \"times_seen\": 3.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.003669870559036333, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0195, \"times_seen\": 29.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.00021236724481496873, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -0.1131, \"times_seen\": 29.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.022900329151020804, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0819, \"times_seen\": 10.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.017404970522975287, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -0.1616, \"times_seen\": 13.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.5318081673104181, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0184, \"times_seen\": 19.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": -0.006131028708939734, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.1903, \"times_seen\": 11.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.23263057690347985, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.0202, \"times_seen\": 16.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.07383631819541225, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.2334, \"times_seen\": 21.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.020443368727585086, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.2764, \"times_seen\": 33.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.0006514177265570181, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.4791, \"times_seen\": 5.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.01213385882221477, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.2852, \"times_seen\": 6.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.02903041046767116, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": 0.1185, \"times_seen\": 39.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.09875336879627468, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": 0.0123, \"times_seen\": 35.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"H\", \"escape\": -0.005268381169207298, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.2269, \"times_seen\": 1.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.02412775815859495, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.0932, \"times_seen\": 22.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.027278514501127837, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": -0.0807, \"times_seen\": 30.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.006771347463740847, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": -0.1024, \"times_seen\": 26.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.01574788260331855, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.1541, \"times_seen\": 5.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.011254939592399567, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": -0.6476, \"times_seen\": 3.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": 0.24504441264701193, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.075, \"times_seen\": 88.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.8840938552150566, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.175, \"times_seen\": 42.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": -0.02946072711275099, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.2332, \"times_seen\": 24.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": -0.012082324449644253, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0566, \"times_seen\": 40.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.5778166754403478, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0043, \"times_seen\": 75.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": -0.09010025690702772, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0638, \"times_seen\": 64.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.07952574569327449, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0169, \"times_seen\": 66.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.11394497850295025, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0243, \"times_seen\": 48.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": 0.3983631423285326, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.3255, \"times_seen\": 60.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.9315816809661055, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0666, \"times_seen\": 68.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": 0.0008063229283301451, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0796, \"times_seen\": 29.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.04688779112981388, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.1479, \"times_seen\": 181.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.012795120228013606, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.1346, \"times_seen\": 95.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.032666708861444745, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.2682, \"times_seen\": 142.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.1509364382278402, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0793, \"times_seen\": 132.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.5254035216730887, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0044, \"times_seen\": 94.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.013905983058905702, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0387, \"times_seen\": 106.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": -0.07960844458577714, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0425, \"times_seen\": 31.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.01968391108261165, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0488, \"times_seen\": 34.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"*\", \"escape\": -0.016494534308300352, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -2.6513, \"times_seen\": 6.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": 0.3074248779119262, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0731, \"times_seen\": 130.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"K\", \"escape\": 0.16524766228948454, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0748, \"times_seen\": 121.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.032081667068623775, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": -0.0551, \"times_seen\": 39.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"N\", \"escape\": 0.013280653882868601, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"R\", \"escape\": -0.03047643822957261, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0645, \"times_seen\": 12.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": 0.06498574070101895, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": -0.0037, \"times_seen\": 38.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": -0.08423089271893232, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": -0.0063, \"times_seen\": 46.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"W\", \"escape\": 0.003894188248074094, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.1881, \"times_seen\": 13.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"Y\", \"escape\": 0.029094897082164842, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.1976, \"times_seen\": 19.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.006703151133538899, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0751, \"times_seen\": 100.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.01708944587250998, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.359, \"times_seen\": 40.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.01962806218757067, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0638, \"times_seen\": 47.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -0.07200148110851703, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2507, \"times_seen\": 48.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.14634779248661192, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0331, \"times_seen\": 128.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.2983761057036368, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0807, \"times_seen\": 106.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.3120829215415435, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2644, \"times_seen\": 32.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -0.006850332519905173, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": 0.1292, \"times_seen\": 27.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.6506522333611828, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2273, \"times_seen\": 61.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.01613415345502605, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.4233, \"times_seen\": 20.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.2673133741843231, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0223, \"times_seen\": 168.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": -0.04717247406808096, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.1434, \"times_seen\": 44.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.055560217351464214, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0238, \"times_seen\": 20.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.0023682850632034346, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.1216, \"times_seen\": 68.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.678760557111264, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0435, \"times_seen\": 115.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.09742645763776138, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0833, \"times_seen\": 105.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.07259205500262035, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2056, \"times_seen\": 80.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.02431212492604487, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.3205, \"times_seen\": 13.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.11706631384454075, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2031, \"times_seen\": 137.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.07214462122785102, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.1159, \"times_seen\": 80.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.06588869317564307, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.002467975993532384, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.1622, \"times_seen\": 3.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.0030902458157204588, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.2061, \"times_seen\": 27.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.16378057897143508, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.1583, \"times_seen\": 13.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.048467447374669334, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.0705, \"times_seen\": 32.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.017393018462145384, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.2258, \"times_seen\": 1.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.3687250992090217, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.1565, \"times_seen\": 22.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.007352591305704293, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.0057, \"times_seen\": 60.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.04841487769961418, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.0243, \"times_seen\": 83.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.029879930184774344, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": 0.0545, \"times_seen\": 62.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.0030926159573865684, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.2727, \"times_seen\": 8.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -1.3824151339693715, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": 0.0304, \"times_seen\": 13.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.0241678081495332, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.137, \"times_seen\": 50.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.07761553679997496, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0627, \"times_seen\": 47.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.0348128973778122, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0515, \"times_seen\": 4.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.12438954437545445, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0625, \"times_seen\": 42.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.29789643021268136, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0764, \"times_seen\": 47.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.0022177258112490235, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": -0.2688, \"times_seen\": 14.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.12173031923023263, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": -0.0258, \"times_seen\": 36.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.016491505818092292, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0761, \"times_seen\": 22.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.08973190694241522, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.016, \"times_seen\": 37.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": 0.006621162653097373, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0869, \"times_seen\": 1.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.01986445415891019, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0575, \"times_seen\": 104.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.09021843580299099, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0654, \"times_seen\": 15.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.06506350080900351, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0764, \"times_seen\": 131.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.018708853553819293, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -0.0279, \"times_seen\": 17.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.36624882182984203, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0177, \"times_seen\": 116.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.015884685555900946, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.2054, \"times_seen\": 22.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": 0.0048169201128330265, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.9592655383565907, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.1254, \"times_seen\": 23.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.05975763802526404, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -0.0332, \"times_seen\": 102.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.009662329926929001, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0011, \"times_seen\": 13.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.18395184800541942, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0052, \"times_seen\": 74.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.004238128152490544, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -0.4437, \"times_seen\": 8.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.023913043415597125, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0312, \"times_seen\": 51.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": 0.020962636367578613, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.1608, \"times_seen\": 6.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"Y\", \"escape\": 0.014885901385616608, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0808, \"times_seen\": 3.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.00442385979156653, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -2.6882, \"times_seen\": 5.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"-\", \"escape\": 0.004270940228267663, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.013241913303730824, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.1384, \"times_seen\": 15.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.02783929954039853, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.0037406182110508567, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0672, \"times_seen\": 133.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.022274813881568253, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0312, \"times_seen\": 76.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.013017455761608425, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0414, \"times_seen\": 49.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.02652790617236831, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0329, \"times_seen\": 49.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.13825748625034298, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0399, \"times_seen\": 38.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.014503075456457288, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": -0.0217, \"times_seen\": 24.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.047459912834934455, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": -0.0815, \"times_seen\": 66.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.021303505343775613, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.027, \"times_seen\": 16.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.03405592387677578, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0688, \"times_seen\": 28.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.003161483058359305, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.1598, \"times_seen\": 1.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.00482192415522604, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0153, \"times_seen\": 24.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.048986346782670574, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0256, \"times_seen\": 44.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.03189671113501908, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0144, \"times_seen\": 46.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.01589116717972346, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0381, \"times_seen\": 13.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.005143909289861157, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": 0.0674, \"times_seen\": 2.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.3803830528554416, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.0127, \"times_seen\": 50.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.035240027238598544, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.1137, \"times_seen\": 18.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.0014759777138553057, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.3116, \"times_seen\": 2.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.003047489856217157, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.1255, \"times_seen\": 27.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.005374577816348951, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.1238, \"times_seen\": 22.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.6234617908039024, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": -0.0472, \"times_seen\": 36.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.007280122461771141, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": -0.0964, \"times_seen\": 3.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.014514335391065215, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": -0.1389, \"times_seen\": 15.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.02569624166992655, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.0499, \"times_seen\": 9.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.040863337095042834, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.012, \"times_seen\": 18.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.04474846052974632, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.1074, \"times_seen\": 73.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.02329217270945091, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.2032, \"times_seen\": 18.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.08409027101355133, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.0384, \"times_seen\": 62.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.022189712238658982, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.1499, \"times_seen\": 25.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.013743171128117217, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.1391, \"times_seen\": 11.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.009760277213637565, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.143, \"times_seen\": 3.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.011798009176617141, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -2.8453, \"times_seen\": 5.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0006917915117325327, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.0038279457399479936, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -0.9961, \"times_seen\": 1.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.025881531556817987, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.0488, \"times_seen\": 25.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": 0.02799308233538795, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.184, \"times_seen\": 4.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.010869647047456405, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.0704, \"times_seen\": 28.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.09673827867701015, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.2213, \"times_seen\": 35.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.009181914811553785, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.0191, \"times_seen\": 8.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.10245459919868256, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.0367, \"times_seen\": 42.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.006664100313393651, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.0793, \"times_seen\": 17.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.0019884468919251865, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -2.6406, \"times_seen\": 1.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.02055174407688285, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -2.9466, \"times_seen\": 4.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": -0.003298374113616419, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -1.0278, \"times_seen\": 1.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.0063638781088376185, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -1.948, \"times_seen\": 4.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": 0.00017375712033175224, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -1.3138, \"times_seen\": 1.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.014704504446422963, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.3386, \"times_seen\": 4.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.06713128755179944, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.2058, \"times_seen\": 24.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.0074673640178574835, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.8613, \"times_seen\": 2.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.012024675735980535, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.2117, \"times_seen\": 12.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0049106911377368185, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": 0.1895, \"times_seen\": 1.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.008098510912879959, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -0.3795, \"times_seen\": 12.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.06807992464345093, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": 0.1124, \"times_seen\": 43.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.03500797618961245, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -0.4666, \"times_seen\": 15.0}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.004894361647644599, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.6875, \"times_seen\": 3.0}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.016355659366774192, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.1861, \"times_seen\": 7.0}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"M\", \"escape\": 0.0005159970872726324, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -1.0215, \"times_seen\": 1.0}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.03672149651255652, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.537, \"times_seen\": 6.0}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.008401152346044116, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.015423146776264787, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -1.997, \"times_seen\": 3.0}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.25796725854433605, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -0.7651, \"times_seen\": 42.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.004969123494981526, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": -0.2374, \"times_seen\": 1.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"E\", \"escape\": 0.011665349130866238, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.2717, \"times_seen\": 7.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.024969034819163162, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.3306, \"times_seen\": 16.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.012710822868710857, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": -0.752, \"times_seen\": 4.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.0006251977748376341, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.249, \"times_seen\": 9.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.02565307290571845, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.3514, \"times_seen\": 10.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.01352700364469972, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.4293, \"times_seen\": 14.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.016590239712397672, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.0857, \"times_seen\": 11.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.005504138574299042, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.1366, \"times_seen\": 2.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 7.312752232473005e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.33, \"times_seen\": 9.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.007816090391484388, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.0423, \"times_seen\": 34.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.024330889329227782, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.1628, \"times_seen\": 19.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": 0.004293481050163677, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.0628, \"times_seen\": 7.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.009914931531977688, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.1032, \"times_seen\": 14.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.32886004916923584, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.3554, \"times_seen\": 10.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.06750796765691155, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.0112, \"times_seen\": 29.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.006766234439828429, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.041, \"times_seen\": 24.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.0032714843406347633, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.0024, \"times_seen\": 16.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.07961014516312577, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.3645, \"times_seen\": 14.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.009512892380018397, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.081, \"times_seen\": 14.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.039246347695639665, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.2591, \"times_seen\": 11.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.03182448766794407, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -1.1385, \"times_seen\": 43.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.01781055357926904, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.8634, \"times_seen\": 41.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.04900301443936359, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.7793, \"times_seen\": 9.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.045114759456733156, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.2356, \"times_seen\": 23.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.051823733407484585, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.9871, \"times_seen\": 33.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.0034809158097673823, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.2722, \"times_seen\": 4.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.005325834589642748, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.2463, \"times_seen\": 39.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": 0.002674075533814499, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.005570898947865214, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4444, \"times_seen\": 13.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.4441237383720862, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.1067, \"times_seen\": 58.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.05755797350377756, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.024291321477505987, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.338, \"times_seen\": 8.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.0057427489194203825, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.0289, \"times_seen\": 6.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"escape\": -0.0012529831196950352, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.0030501283311028023, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.1425, \"times_seen\": 1.0}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.030331805690562524, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.3392, \"times_seen\": 14.0}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.011950078608176836, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": -1.9717, \"times_seen\": 3.0}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.009612434150482877, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.255, \"times_seen\": 1.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.0021393359306719115, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.5772, \"times_seen\": 8.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.014069554896876507, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.2777, \"times_seen\": 4.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.027314355801547233, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.3112, \"times_seen\": 29.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -1.3051761959416182, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": 0.0764, \"times_seen\": 49.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.029191590848171467, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": 0.0004, \"times_seen\": 6.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.03553835515313717, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.2275, \"times_seen\": 46.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.03162071207003564, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.3953, \"times_seen\": 67.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.053636272480508194, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.445, \"times_seen\": 20.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.12229725963137587, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.0588, \"times_seen\": 58.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.00028454496570138525, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -0.7565, \"times_seen\": 17.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.34591833869359495, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -0.0822, \"times_seen\": 41.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.11335760027581923, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -0.164, \"times_seen\": 65.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.9086998126965363, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": 0.0432, \"times_seen\": 13.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.0017962289413102949, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": 0.1136, \"times_seen\": 1.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.02364524769252585, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0281, \"times_seen\": 10.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.008388155209397898, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.0198, \"times_seen\": 3.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.14190751083695013, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.1648, \"times_seen\": 49.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.075879693738101, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.2185, \"times_seen\": 26.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.32517497891931824, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0784, \"times_seen\": 31.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.04216012777974074, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.0072, \"times_seen\": 19.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.005834043790713183, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0049, \"times_seen\": 5.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.0263043872437848, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0358, \"times_seen\": 16.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": 0.0590764714302253, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.1606, \"times_seen\": 6.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.018970983641405995, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.6104, \"times_seen\": 9.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.0032437245338154458, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": 0.1011, \"times_seen\": 1.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.01788532770612782, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.0949, \"times_seen\": 8.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.017130997276861373, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.6998, \"times_seen\": 10.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.0029807318311602243, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.9007, \"times_seen\": 9.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.053731087190313026, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.2913, \"times_seen\": 27.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.012800251531666014, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": -0.0017540752583356614, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": 0.001356265163126585, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0465, \"times_seen\": 10.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.0022236962730392113, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0726, \"times_seen\": 19.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": -0.04079966645998415, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0033, \"times_seen\": 12.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": 0.07190203022190687, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": 0.0603, \"times_seen\": 25.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": 0.008558248388679655, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.1124, \"times_seen\": 6.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.020567682083670057, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0474, \"times_seen\": 70.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.052933372284465624, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0387, \"times_seen\": 44.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.07030988006206797, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0312, \"times_seen\": 41.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.00888878056740318, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.1878, \"times_seen\": 17.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.005447110781528146, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0927, \"times_seen\": 6.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.055962106065998, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0399, \"times_seen\": 38.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.016059796639108656, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.2993, \"times_seen\": 11.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 0.05181352681186832, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.2003, \"times_seen\": 63.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.0026730606510458246, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.045, \"times_seen\": 55.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.0016557291569105582, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.0731, \"times_seen\": 6.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.04223140285869677, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.0513, \"times_seen\": 14.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.0019756562634205524, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": -0.0455, \"times_seen\": 33.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.015234335578912699, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.1251, \"times_seen\": 29.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.0038261658336871383, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0024, \"times_seen\": 33.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.016866360987775806, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0427, \"times_seen\": 4.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.0018092761158565115, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.1542, \"times_seen\": 6.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.7124844578979795, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0091, \"times_seen\": 66.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.0003741549849419076, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -0.0732, \"times_seen\": 28.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.032765885608026526, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -0.0985, \"times_seen\": 21.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.05790082051519076, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -0.0943, \"times_seen\": 21.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"A\", \"escape\": -1.8763254468627966, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0728, \"times_seen\": 122.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"C\", \"escape\": 0.11662617355182266, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0454, \"times_seen\": 97.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"D\", \"escape\": -0.28874044225312645, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0567, \"times_seen\": 102.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"E\", \"escape\": -0.060354994234164884, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.065, \"times_seen\": 42.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.015364588276534514, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0738, \"times_seen\": 149.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"G\", \"escape\": 0.08664211590173472, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0576, \"times_seen\": 81.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"H\", \"escape\": -0.5219658705301871, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0446, \"times_seen\": 96.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": 0.014182391320315504, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0143, \"times_seen\": 34.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.3512751313506298, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0161, \"times_seen\": 133.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.05729914941803067, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0034, \"times_seen\": 32.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.09784047542254928, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0533, \"times_seen\": 96.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"P\", \"escape\": 0.5864197193499113, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0835, \"times_seen\": 89.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"Q\", \"escape\": -0.24406137722676968, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.1415, \"times_seen\": 24.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"R\", \"escape\": -0.2967370085862851, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0084, \"times_seen\": 153.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.09301034170212466, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0246, \"times_seen\": 308.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.039276677191178014, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.052, \"times_seen\": 149.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.07135047141106174, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0672, \"times_seen\": 149.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"W\", \"escape\": -0.01938789933770153, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0393, \"times_seen\": 25.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": 0.06471124602847322, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0431, \"times_seen\": 81.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"*\", \"escape\": -0.0005235251359577454, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -2.7994, \"times_seen\": 4.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.04970803759859567, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0563, \"times_seen\": 71.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.08818040411413995, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0368, \"times_seen\": 30.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.03743069588479261, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": -0.0004, \"times_seen\": 25.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.025844387941914793, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0089, \"times_seen\": 17.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.3639623273253778, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": -0.0977, \"times_seen\": 82.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.19617557058882412, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0099, \"times_seen\": 99.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"P\", \"escape\": 0.005657035656267656, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.1557, \"times_seen\": 5.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": 1.2653523822459207, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0342, \"times_seen\": 27.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.6084796543512534, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": -0.1629, \"times_seen\": 16.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"A\", \"escape\": 0.010353168756264285, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0533, \"times_seen\": 4.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": 0.05209702789399398, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.2796, \"times_seen\": 16.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.010533911713714284, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0487, \"times_seen\": 5.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.031998411875632196, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.2323, \"times_seen\": 16.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": 0.025566793757930938, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.1525, \"times_seen\": 10.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": 0.05634641441119212, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.1284, \"times_seen\": 13.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.00036102355380209314, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0091, \"times_seen\": 5.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.023690001295780458, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0282, \"times_seen\": 17.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.0243692614013487, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.4161, \"times_seen\": 4.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"P\", \"escape\": 0.015066285699255088, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0108, \"times_seen\": 1.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.007444755150428107, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0509, \"times_seen\": 33.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"Y\", \"escape\": -0.02403124342207003, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0297, \"times_seen\": 8.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": -0.025121614422984155, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.1074, \"times_seen\": 19.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.16637763472392397, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0425, \"times_seen\": 111.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"C\", \"escape\": -0.20845153350437162, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.283, \"times_seen\": 29.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.04067055723685837, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0912, \"times_seen\": 81.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"F\", \"escape\": -0.034524890232569536, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.016, \"times_seen\": 28.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.4040377058631113, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0477, \"times_seen\": 115.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"H\", \"escape\": -0.07491379350428656, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0683, \"times_seen\": 38.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"I\", \"escape\": -0.03415428080042926, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0731, \"times_seen\": 23.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.2568376943148358, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0464, \"times_seen\": 72.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"L\", \"escape\": -0.24743422004274718, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0069, \"times_seen\": 118.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"M\", \"escape\": -0.10822683706156382, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0198, \"times_seen\": 34.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": -0.03490743172696046, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0274, \"times_seen\": 42.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"P\", \"escape\": -0.17695395029284672, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.019, \"times_seen\": 78.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.0021000313890935807, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0158, \"times_seen\": 65.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -0.0017192115372745601, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0711, \"times_seen\": 118.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": -1.9816385306808904, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0461, \"times_seen\": 117.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"T\", \"escape\": 0.13714354293156286, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0859, \"times_seen\": 81.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.027364325753640586, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0544, \"times_seen\": 70.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"W\", \"escape\": 0.03020394952500961, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.043, \"times_seen\": 30.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"Y\", \"escape\": -0.1375361425663486, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0822, \"times_seen\": 29.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": 0.01606147733834551, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -2.8369, \"times_seen\": 2.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.013833866965183465, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0818, \"times_seen\": 89.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"C\", \"escape\": -0.6113924440393093, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.1751, \"times_seen\": 43.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"D\", \"escape\": -0.051434343353845405, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0387, \"times_seen\": 29.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"E\", \"escape\": -0.1803178059301187, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0924, \"times_seen\": 13.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"F\", \"escape\": 0.28370848423258943, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1341, \"times_seen\": 45.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": -0.027116419340932715, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0187, \"times_seen\": 50.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.007544908995927295, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0759, \"times_seen\": 65.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"I\", \"escape\": -8.846641393081218e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1244, \"times_seen\": 35.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"K\", \"escape\": 0.024050538235927323, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1741, \"times_seen\": 21.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.08073428058220185, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0442, \"times_seen\": 165.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": 0.09160466196522479, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0042, \"times_seen\": 25.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"N\", \"escape\": 0.1914306359303097, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0743, \"times_seen\": 46.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.06776003761601435, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.048, \"times_seen\": 30.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.20278186352738253, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0616, \"times_seen\": 139.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.014843999300855483, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0353, \"times_seen\": 162.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.07705710677618702, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0405, \"times_seen\": 108.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": -0.026949275096711824, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0603, \"times_seen\": 33.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"W\", \"escape\": -0.033167252548429206, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1366, \"times_seen\": 17.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"Y\", \"escape\": -0.06086146775263775, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0338, \"times_seen\": 40.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"*\", \"escape\": -0.035494072323056555, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -2.2306, \"times_seen\": 3.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.01840976556095693, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0406, \"times_seen\": 142.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"C\", \"escape\": -0.016117995635373087, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0276, \"times_seen\": 36.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.2144772573960569, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0312, \"times_seen\": 120.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"F\", \"escape\": 0.0026076155944157017, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0032, \"times_seen\": 77.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.22251506268762614, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0664, \"times_seen\": 203.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"H\", \"escape\": -1.3514686163426513, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0951, \"times_seen\": 43.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"I\", \"escape\": 0.002837771690351343, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.135, \"times_seen\": 52.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.04457732766955046, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0204, \"times_seen\": 105.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"L\", \"escape\": 0.11906073227327116, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0025, \"times_seen\": 174.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"M\", \"escape\": -0.22838737222096966, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0072, \"times_seen\": 84.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": -0.22690627995432824, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0045, \"times_seen\": 43.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"P\", \"escape\": -0.07235346819767026, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0316, \"times_seen\": 115.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.057952100162280876, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0557, \"times_seen\": 81.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -0.04073822183435407, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0215, \"times_seen\": 184.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": -0.025489613072206957, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0276, \"times_seen\": 177.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"T\", \"escape\": -0.01720447309240681, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0269, \"times_seen\": 102.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.013430543666761285, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0171, \"times_seen\": 181.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"W\", \"escape\": -0.03534964620925679, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0405, \"times_seen\": 71.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"Y\", \"escape\": 0.47279811778467584, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.066, \"times_seen\": 63.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": 0.7480532162497477, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -2.7538, \"times_seen\": 10.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"-\", \"escape\": 0.01522210068306596, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0252, \"times_seen\": 1.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.07627714865253114, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1064, \"times_seen\": 201.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.07062841204085067, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.2074, \"times_seen\": 59.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.17461500287468096, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0597, \"times_seen\": 127.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -0.177434727152062, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1832, \"times_seen\": 51.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.13119869313855265, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1224, \"times_seen\": 143.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.1071490518487083, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0769, \"times_seen\": 207.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.03883078122999441, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": 0.0437, \"times_seen\": 74.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -0.0411460545675636, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.026, \"times_seen\": 35.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.07473727516774928, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1598, \"times_seen\": 101.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.0027860491773230517, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1444, \"times_seen\": 34.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.03331299727132703, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0638, \"times_seen\": 226.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": -0.31462727097943477, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1075, \"times_seen\": 108.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": -0.10595666033760506, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0803, \"times_seen\": 18.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": 0.0720421352876356, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.2016, \"times_seen\": 93.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -2.3438406886542147, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0871, \"times_seen\": 213.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.0168850658938818, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1353, \"times_seen\": 135.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.12025703796234341, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0999, \"times_seen\": 141.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.11005982414805093, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.2008, \"times_seen\": 12.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.07540214720180775, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0367, \"times_seen\": 271.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": 0.05174723292245493, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -2.5539, \"times_seen\": 3.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.12845736987471562, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.1345, \"times_seen\": 44.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.026827423489685327, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.0486, \"times_seen\": 14.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.046539049635968444, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.0678, \"times_seen\": 11.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -1.2518677022130638, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.8257, \"times_seen\": 85.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.009371548761677881, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.8349, \"times_seen\": 3.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.00473940549286194, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.7414, \"times_seen\": 2.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.010095917210220627, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -1.2806, \"times_seen\": 2.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": 0.00644710192674791, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -1.3884, \"times_seen\": 4.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.036837200709100425, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.1613, \"times_seen\": 14.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.03489922558508944, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": -0.0103, \"times_seen\": 7.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.012125338230018606, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.2183, \"times_seen\": 4.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.017482318915211747, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": -0.003, \"times_seen\": 31.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0011524027658642133, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": -0.062, \"times_seen\": 6.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.00849643095823631, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0077, \"times_seen\": 64.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.13545289965873392, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0328, \"times_seen\": 124.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.05825235416202236, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.0633, \"times_seen\": 24.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.07320990664849088, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1397, \"times_seen\": 85.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.013586934677867979, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1498, \"times_seen\": 11.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.007320295710577592, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1316, \"times_seen\": 92.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": 0.009991958576565938, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1756, \"times_seen\": 7.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.010353589557048688, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.2669, \"times_seen\": 123.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.19107971213302669, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.1246, \"times_seen\": 136.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 0.02048541791978611, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.3667, \"times_seen\": 1.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.002671518114723331, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0003, \"times_seen\": 1.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.22846074016567383, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.0416, \"times_seen\": 88.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.0771822137535965, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.0095, \"times_seen\": 40.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.012885587915722693, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.0326, \"times_seen\": 16.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.04058778800974806, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.003, \"times_seen\": 18.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.048900927273715734, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": -1.1228, \"times_seen\": 2.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.01377252760634633, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.1777, \"times_seen\": 6.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0025440941775636103, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": -1.0107, \"times_seen\": 1.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.05706832874230597, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.1215, \"times_seen\": 8.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.006895396936128696, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.343, \"times_seen\": 1.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.007909115999324656, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.326, \"times_seen\": 20.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.02640724926639932, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.03883727469424932, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -1.9303, \"times_seen\": 18.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.033865935032980576, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0561, \"times_seen\": 6.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.04217102857216895, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0753, \"times_seen\": 12.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.005023758117798573, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.2838, \"times_seen\": 5.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.005884097370726115, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.0299, \"times_seen\": 3.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.15557212639454482, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.0102, \"times_seen\": 35.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.046169924796598295, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.4087, \"times_seen\": 43.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.14998599347814043, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.5791, \"times_seen\": 6.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": 0.013336467955206205, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.6507, \"times_seen\": 24.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.1733158205155978, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.2606, \"times_seen\": 66.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.0019837872929707088, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -2.2013, \"times_seen\": 5.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": 0.027023903994133562, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.1774, \"times_seen\": 43.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.03293543520101805, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -3.1135, \"times_seen\": 1.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.1702677602142827, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.1977, \"times_seen\": 61.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.010087176370479371, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.6407, \"times_seen\": 12.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.023382890223230573, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.8643, \"times_seen\": 13.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.025479748807277228, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.1476, \"times_seen\": 120.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.011563536324232168, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.4284, \"times_seen\": 10.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.008948694283930032, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.8129, \"times_seen\": 13.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.4967781054975039, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.2461, \"times_seen\": 124.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.3086956696387835, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.0355, \"times_seen\": 139.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.015477077062282876, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.1999, \"times_seen\": 102.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": 0.009709138946677765, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.9779, \"times_seen\": 4.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": 0.039882530121107894, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.8799, \"times_seen\": 9.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.01742827573543517, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -2.9784, \"times_seen\": 2.0}, {\"site\": 220, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0009589564531662823, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -0.2449, \"times_seen\": 1.0}, {\"site\": 220, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.0175022537421752, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -1.6638, \"times_seen\": 8.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.0188365396722741, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.3753, \"times_seen\": 9.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.005258513683008068, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -1.0164, \"times_seen\": 8.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.006056113768241219, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.878, \"times_seen\": 21.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": -0.026053014304696514, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -1.3309, \"times_seen\": 6.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.0062239938632454635, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": 0.0509, \"times_seen\": 5.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.0035840131577874594, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.1249, \"times_seen\": 1.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 0.0020597762165998515, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.1521, \"times_seen\": 13.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.04822217256324158, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -1.3977, \"times_seen\": 21.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.005567695272727695, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.501, \"times_seen\": 1.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.003970115335150151, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.604, \"times_seen\": 1.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.023426349879576508, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.1988, \"times_seen\": 7.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": -0.012096355487630828, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.4981, \"times_seen\": 4.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.002641470294645951, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.2731, \"times_seen\": 46.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.017056014198518217, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0083, \"times_seen\": 9.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.0014082391920607251, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.0651, \"times_seen\": 1.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.0016367623071764845, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -2.1574, \"times_seen\": 1.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.006002606052447889, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0396, \"times_seen\": 2.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.00041310578022841707, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.6241, \"times_seen\": 5.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.15076956734981203, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.1381, \"times_seen\": 24.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.041101733514964864, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.1855, \"times_seen\": 28.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.08202470835638079, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.638, \"times_seen\": 9.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.019802484435210054, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.0408, \"times_seen\": 23.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.015300549539524316, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.1253, \"times_seen\": 44.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.0225823156505994, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.1129, \"times_seen\": 9.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.0024788484174889133, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.0495, \"times_seen\": 10.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.03741103546713616, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.0925, \"times_seen\": 14.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.10907282093635093, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.023, \"times_seen\": 23.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.05113137925134734, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.3678, \"times_seen\": 57.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.8233404771661846, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.2091, \"times_seen\": 58.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.021354880037205617, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": 0.1782, \"times_seen\": 33.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.009120744519490171, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.0463, \"times_seen\": 5.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.024413622332995634, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.3219, \"times_seen\": 13.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.004866175832348838, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.3542, \"times_seen\": 2.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.017538427008844584, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.0169, \"times_seen\": 56.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.025546310013838367, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -0.4365, \"times_seen\": 19.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 1.1495367304430438e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -0.1964, \"times_seen\": 10.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.008078646425379506, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -1.6609, \"times_seen\": 10.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.03118476109713528, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -0.715, \"times_seen\": 5.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.01835150598038628, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": 0.1363, \"times_seen\": 1.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.027992008711967078, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": 0.2964, \"times_seen\": 9.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": 0.003346938375303282, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.0536, \"times_seen\": 2.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.030442097874431848, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -1.4392, \"times_seen\": 31.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.008631417541872542, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.6773, \"times_seen\": 7.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.0055877576401220245, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": 0.3933, \"times_seen\": 14.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0385431192278796, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.1116, \"times_seen\": 19.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": 0.008793529582630693, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.2995, \"times_seen\": 4.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.009433157685870391, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.6077, \"times_seen\": 2.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.47436336161377807, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.7924, \"times_seen\": 7.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -1.157352885165017, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.3036, \"times_seen\": 17.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.006013926989087117, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -1.1128, \"times_seen\": 5.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.036330592819671534, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": 0.1064, \"times_seen\": 24.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.050295855099957966, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": 0.2946, \"times_seen\": 7.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.0005649073487346091, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.0781, \"times_seen\": 19.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.1400746489261788, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.0445, \"times_seen\": 60.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.5977464998038627, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.2295, \"times_seen\": 42.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.01332241660900199, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -1.2574, \"times_seen\": 6.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.027964276210905827, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.8465, \"times_seen\": 16.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.02470203489330228, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.1679, \"times_seen\": 35.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.08881998377071842, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.1446, \"times_seen\": 31.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.0014874784093008879, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.1623, \"times_seen\": 2.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.0027443210882912043, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -0.4334, \"times_seen\": 7.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.921509950757949, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -0.4892, \"times_seen\": 12.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.008725613512527331, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.0266, \"times_seen\": 10.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.016405355114690885, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -1.2702, \"times_seen\": 6.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.0076956783357095965, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.1887, \"times_seen\": 15.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.04295362103251235, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.2882, \"times_seen\": 10.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.6645617633377058, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.0597, \"times_seen\": 27.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"P\", \"escape\": -0.016557502765690058, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.4295, \"times_seen\": 9.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.028916680090139955, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": -0.0906, \"times_seen\": 2.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.032800323913196976, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.06349989795763625, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.2545, \"times_seen\": 23.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.0027092471510002276, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": -3.2703, \"times_seen\": 1.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"A\", \"escape\": 0.01453228622140635, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.9604, \"times_seen\": 2.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.03579630350861189, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.5704, \"times_seen\": 15.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0069390001257812525, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.2026, \"times_seen\": 3.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.015413295171442791, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -1.1048, \"times_seen\": 7.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.08602825291113851, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -1.0273, \"times_seen\": 10.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.010298046355674165, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.665, \"times_seen\": 3.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": 0.0005260424172646843, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.015579568055234957, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.0943, \"times_seen\": 2.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.03822415511583952, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": -0.123, \"times_seen\": 4.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.0023232051252573263, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.010819469683249098, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.011354248027050692, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": -0.1354, \"times_seen\": 4.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.02419140831467822, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.3651, \"times_seen\": 8.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": 0.00016427166579269155, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": 0.015362459661086693, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.1122, \"times_seen\": 16.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.0064502599000309324, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.0881, \"times_seen\": 35.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.03894253231195304, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.0887, \"times_seen\": 56.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.09227911954187741, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.1069, \"times_seen\": 60.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.05059663688398326, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": 0.0239, \"times_seen\": 59.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.006113269317070067, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": 0.1662, \"times_seen\": 2.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"Y\", \"escape\": -0.024155230121192226, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.2899, \"times_seen\": 17.0}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.05932398288968251, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.1208, \"times_seen\": 15.0}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.00996211432377633, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.2954, \"times_seen\": 13.0}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.0016935884704903335, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -2.7351, \"times_seen\": 1.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.011254820758984464, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.0871, \"times_seen\": 6.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.008999338084093079, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.1024, \"times_seen\": 20.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.01538848665718405, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": 0.0548, \"times_seen\": 14.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.02558396675042853, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.0449, \"times_seen\": 21.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.12998236428232524, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.018, \"times_seen\": 77.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": -0.004015421668485584, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": 0.1525, \"times_seen\": 2.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": 0.10769862561401114, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -3.0623, \"times_seen\": 1.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.026703770383677373, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0885, \"times_seen\": 13.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.06142258592216004, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0874, \"times_seen\": 49.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.007204194193511068, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.169, \"times_seen\": 2.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.021807787438814855, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.4746, \"times_seen\": 8.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.0011370257870016076, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0441, \"times_seen\": 5.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.0030891047661504027, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0511, \"times_seen\": 10.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.005723200058645964, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.4513, \"times_seen\": 7.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.009032005703276192, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.0413, \"times_seen\": 2.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.013627580035864378, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.1915, \"times_seen\": 2.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.003575545286250872, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.4464, \"times_seen\": 8.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.004269752714721173, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -1.983, \"times_seen\": 2.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0035899345549970257, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.022393128244867895, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": 0.077, \"times_seen\": 15.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.008561588204581926, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.453, \"times_seen\": 5.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.02230318958001844, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.0169, \"times_seen\": 26.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.0050668952204076575, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.1729, \"times_seen\": 13.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.011996471993743808, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.3791, \"times_seen\": 8.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.004923636438655763, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.1038, \"times_seen\": 7.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.009607554015873342, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.1964, \"times_seen\": 3.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.013615186198447348, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.1182, \"times_seen\": 9.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.05588388913890254, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.1558, \"times_seen\": 6.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.007400158978559892, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.0741, \"times_seen\": 5.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.01327192076380484, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.0102, \"times_seen\": 4.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": 0.001151749533706447, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.0411, \"times_seen\": 3.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.017485049942454665, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.0762, \"times_seen\": 14.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.01574040939786887, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.003, \"times_seen\": 27.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.033590162978830475, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.5302, \"times_seen\": 13.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 1.4233208128046237, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -6.00413823320321e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.1752, \"times_seen\": 4.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.06126111007298548, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.1026, \"times_seen\": 14.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.04113017567948989, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0128, \"times_seen\": 56.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.3239116922587716, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.0384, \"times_seen\": 93.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.0509377118625348, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.0605, \"times_seen\": 48.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.009055057963275211, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.0469, \"times_seen\": 12.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": -0.01577730235650145, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0648, \"times_seen\": 23.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": -0.007063287656186681, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1124, \"times_seen\": 2.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.015522431813631742, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.1492, \"times_seen\": 9.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.008545982134653584, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.0313, \"times_seen\": 6.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -1.2261712053363674, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.0693, \"times_seen\": 8.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.0014017611058567163, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1182, \"times_seen\": 23.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.010817868976938103, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.3063, \"times_seen\": 1.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.02146043598710981, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.2637, \"times_seen\": 10.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.003810365140186884, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1729, \"times_seen\": 9.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.015178832179350999, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.0433, \"times_seen\": 14.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": -0.004457183391846848, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.1089, \"times_seen\": 5.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": 0.017388458156360462, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.628, \"times_seen\": 12.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": 0.03329824268357391, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.0195, \"times_seen\": 11.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": 0.003295358105583611, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.0842, \"times_seen\": 13.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": -0.0112708873128779, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": 0.1609, \"times_seen\": 2.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.016492986380153368, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.0004, \"times_seen\": 17.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": -0.025658206533272627, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.1595, \"times_seen\": 6.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.0941448262882693, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.022, \"times_seen\": 66.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"-\", \"escape\": 0.06248688129808884, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": 0.1197, \"times_seen\": 15.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.008870857681621342, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0858, \"times_seen\": 12.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.13309984650270834, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.1092, \"times_seen\": 62.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.0015392549723305601, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": -0.0162, \"times_seen\": 42.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.03324840680144227, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": -0.0306, \"times_seen\": 46.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.006101932102922012, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.169, \"times_seen\": 9.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.0063204999553938815, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.1541, \"times_seen\": 7.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.667444265117873, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0437, \"times_seen\": 57.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.08855391406241585, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": -0.0659, \"times_seen\": 25.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": 0.011227018435946621, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0583, \"times_seen\": 29.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": 0.021900272767036398, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0957, \"times_seen\": 8.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.01850209255252626, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.0591, \"times_seen\": 7.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.016737359933911535, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.2911, \"times_seen\": 2.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.49733414012360594, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0707, \"times_seen\": 20.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.04688170571546406, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0197, \"times_seen\": 36.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.030973729387708086, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0213, \"times_seen\": 32.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.013712287060918453, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0426, \"times_seen\": 11.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.032663422649928414, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0617, \"times_seen\": 8.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.004373874953699026, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.00046781318368176704, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.0067, \"times_seen\": 2.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 0.06851161089927667, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0932, \"times_seen\": 11.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.04630118667933, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.1126, \"times_seen\": 48.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.001470394269869424, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.12, \"times_seen\": 17.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.06308108520414789, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.0527, \"times_seen\": 61.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.009814802142975343, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.3252, \"times_seen\": 4.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.006235273639505736, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": 0.08714069950629827, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.0493, \"times_seen\": 17.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.0059058403204832206, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -1.6307, \"times_seen\": 2.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"-\", \"escape\": 0.06760806639175972, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.0923, \"times_seen\": 14.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.06977779159989209, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0119, \"times_seen\": 23.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.06058114937380934, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": -0.0304, \"times_seen\": 15.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.008214162215286433, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.054, \"times_seen\": 34.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.00950383187001586, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": -0.1483, \"times_seen\": 2.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.35387605355408513, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0215, \"times_seen\": 3.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.03903846394906056, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0081, \"times_seen\": 15.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.013191101377204967, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": -0.042, \"times_seen\": 5.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.008746945066353243, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.1009, \"times_seen\": 4.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": 0.013276015532899556, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0026, \"times_seen\": 12.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.5088794667456775, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.0908, \"times_seen\": 31.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.018021400484881437, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.2072, \"times_seen\": 6.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.07317032332488718, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.0007, \"times_seen\": 63.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.0067707198966689055, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.3528, \"times_seen\": 6.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.02092276728108065, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0803, \"times_seen\": 5.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.05546101030754503, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0791, \"times_seen\": 48.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.003507655015364271, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0563, \"times_seen\": 12.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.010106556557992226, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0533, \"times_seen\": 7.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.003058869292393156, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.5234, \"times_seen\": 2.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.015947635751248624, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.3226, \"times_seen\": 11.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": 0.026710587170618093, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0723, \"times_seen\": 38.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.1714784080458747, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0713, \"times_seen\": 45.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.02080923734330031, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0358, \"times_seen\": 27.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.01152641972712669, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.4598, \"times_seen\": 4.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.026935135945093325, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0942, \"times_seen\": 18.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.6023300378330027, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0788, \"times_seen\": 39.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": -0.0031935790725227562, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.1832, \"times_seen\": 2.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"Y\", \"escape\": -0.01653624851185574, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": 0.2736, \"times_seen\": 11.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"-\", \"escape\": 0.0006712518909985524, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0369, \"times_seen\": 23.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.055836339322957375, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -0.0529, \"times_seen\": 37.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.013740722691748591, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.2515, \"times_seen\": 11.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": 0.8608680230739716, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -0.3223, \"times_seen\": 10.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.011934069094560816, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.1264, \"times_seen\": 5.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.15475811377709048, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0234, \"times_seen\": 21.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.03202630520665264, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0032, \"times_seen\": 18.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.0024136881081915297, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0587, \"times_seen\": 40.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": 0.02021514330603817, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -2.368, \"times_seen\": 1.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.003071586979406266, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0209, \"times_seen\": 25.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.13082996836192526, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0694, \"times_seen\": 139.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": 0.09584771227126168, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0911, \"times_seen\": 21.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.01154491450614476, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0047, \"times_seen\": 30.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": 0.04791298899354099, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.19, \"times_seen\": 36.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.018303795072183077, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0226, \"times_seen\": 68.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.04886704289583065, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0066, \"times_seen\": 47.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.0037729182199144327, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.1172, \"times_seen\": 25.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -2.067775617364448, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0792, \"times_seen\": 18.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": -0.011290907741668549, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.2095, \"times_seen\": 34.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.012897983242773227, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0103, \"times_seen\": 6.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.3122506391016451, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.048, \"times_seen\": 86.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": -0.02388120791666118, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0621, \"times_seen\": 48.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": -0.023272638308378668, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0404, \"times_seen\": 14.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.20997667961797623, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.1955, \"times_seen\": 43.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.020895691052533423, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0687, \"times_seen\": 85.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.6666644743087744, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.1012, \"times_seen\": 52.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.18247686856984904, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0993, \"times_seen\": 47.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.5587436308943633, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.2328, \"times_seen\": 15.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.10271649469652108, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0098, \"times_seen\": 89.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": -0.007281730114518796, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -1.3579, \"times_seen\": 1.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0041703976641602565, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0229, \"times_seen\": 43.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 1.4601960994838918, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.247, \"times_seen\": 19.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.004179739755420766, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.2769, \"times_seen\": 12.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.01776011459526919, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.1792, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.03115529790844945, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0267, \"times_seen\": 55.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.04572620379578413, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1268, \"times_seen\": 17.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": -0.0017328764930532258, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0095, \"times_seen\": 14.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -1.614247740198665, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.1429, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.02113662196776881, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1052, \"times_seen\": 10.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.012508557691746199, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0779, \"times_seen\": 47.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.002642730100939814, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1178, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0183072033488032, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.2366, \"times_seen\": 13.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.05359631349405071, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0124, \"times_seen\": 98.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.0026283228179931825, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1581, \"times_seen\": 9.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.27313461706492564, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0805, \"times_seen\": 23.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.28329215199480245, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0369, \"times_seen\": 72.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.03138111212291332, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0644, \"times_seen\": 34.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.0005677094976548532, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0808, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.011996471235209508, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0042, \"times_seen\": 51.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.07602686840841359, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.022, \"times_seen\": 34.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.003203179403975519, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1201, \"times_seen\": 9.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.034896366685099246, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.2949, \"times_seen\": 17.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.000992822432708738, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1349, \"times_seen\": 10.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.08980212409193451, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.09, \"times_seen\": 63.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.003385129167995991, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0354, \"times_seen\": 16.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": -0.012641403341626516, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.2111, \"times_seen\": 9.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.021842516169254884, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0747, \"times_seen\": 19.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.005247868844331541, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.1087, \"times_seen\": 11.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.882048147765579, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.0646, \"times_seen\": 45.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.010390897930556257, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1899, \"times_seen\": 5.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.013536532591177462, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.2301, \"times_seen\": 8.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.20301510618990928, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0354, \"times_seen\": 94.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -2.8431202735246917e-06, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.3266, \"times_seen\": 4.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.0047907329156778745, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.222, \"times_seen\": 16.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -1.0186413624987454, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0208, \"times_seen\": 45.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 0.011994790869664772, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.0605, \"times_seen\": 16.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.01559138664962045, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1098, \"times_seen\": 9.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.01133790420339021, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0438, \"times_seen\": 43.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": -0.0014669748539519534, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -2.7623, \"times_seen\": 2.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.01692733105894429, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.2278, \"times_seen\": 9.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0015352967590869168, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.0983, \"times_seen\": 1.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.0066543236886177914, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.1115, \"times_seen\": 2.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.03835987598793326, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.0324, \"times_seen\": 27.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.07912089405771858, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.0483, \"times_seen\": 40.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.01271029141433149, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.3463, \"times_seen\": 12.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.011447459724141231, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.3442, \"times_seen\": 5.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.011520501720021002, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0133, \"times_seen\": 21.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.08154386366579225, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.1041, \"times_seen\": 14.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.09999530012643335, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0256, \"times_seen\": 54.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.004517406270007773, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0481, \"times_seen\": 12.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": -0.03048549658936508, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0854, \"times_seen\": 10.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": 0.04821706913801596, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.2371, \"times_seen\": 9.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": -0.014059206820904967, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.104, \"times_seen\": 6.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.008925784814356233, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.1809, \"times_seen\": 10.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.009730130754050801, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0541, \"times_seen\": 16.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": 0.010531163504686518, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.1249, \"times_seen\": 8.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 0.01653839419848018, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0088, \"times_seen\": 18.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": 0.2369702941610042, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0566, \"times_seen\": 18.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": -0.006636845523920546, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.1361, \"times_seen\": 3.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.042322129815255974, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0423, \"times_seen\": 21.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.2691536497989562, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0097, \"times_seen\": 41.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.7400851243489647, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.021, \"times_seen\": 13.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.014517577022097435, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0902, \"times_seen\": 27.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.02303955524678019, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.2542, \"times_seen\": 10.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"Y\", \"escape\": 5.274521046150554e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.3191, \"times_seen\": 5.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.010184070962777883, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -3.1202, \"times_seen\": 2.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": 0.004070466364034374, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": 0.0905, \"times_seen\": 42.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": -0.00019472584950085578, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.1519, \"times_seen\": 6.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"G\", \"escape\": -0.02857965794144957, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": 0.2637, \"times_seen\": 10.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": -0.013274928856836647, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.1184, \"times_seen\": 15.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": 0.02737965056763254, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.1066, \"times_seen\": 52.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"S\", \"escape\": 0.01730687123711227, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.0135, \"times_seen\": 7.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": 0.02834925317842279, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -1.9373, \"times_seen\": 5.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.015921254309244546, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": -0.0462, \"times_seen\": 21.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.21438866850164925, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.0035, \"times_seen\": 53.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.01820793144599694, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.1198, \"times_seen\": 19.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.0036560114130506955, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.3663, \"times_seen\": 1.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.01053867112571468, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.0819, \"times_seen\": 8.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.007773777345644351, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.059, \"times_seen\": 11.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.043380784192833574, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.377, \"times_seen\": 5.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": 0.006078345079477826, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": -0.159, \"times_seen\": 3.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.9788590812221704, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0856, \"times_seen\": 52.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.002949038199560993, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0222, \"times_seen\": 2.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.008483869446122404, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.035439159529023774, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.181, \"times_seen\": 14.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.016743148284933198, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": -0.042, \"times_seen\": 6.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.010075685865037083, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.1285, \"times_seen\": 9.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.02980470700466561, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": -0.131, \"times_seen\": 36.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.2588344355809145, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0958, \"times_seen\": 46.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.13512730098096004, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0007, \"times_seen\": 71.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.5253959946783163, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0449, \"times_seen\": 78.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.13052800435325926, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0783, \"times_seen\": 58.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.5149147162624512, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0359, \"times_seen\": 73.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.08525491003307678, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.1557, \"times_seen\": 30.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": -0.07333479941179855, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0559, \"times_seen\": 31.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": 0.1637961056053533, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0955, \"times_seen\": 20.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": -0.10202565115802942, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0601, \"times_seen\": 23.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.78942873918718, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.067, \"times_seen\": 5.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.35089262759247164, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0457, \"times_seen\": 58.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.019693033486533566, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0449, \"times_seen\": 9.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -1.2846804009514514, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0278, \"times_seen\": 29.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": 0.17888196334364348, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.047, \"times_seen\": 37.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": 0.0011455265355770157, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.3115, \"times_seen\": 12.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.11851790356061022, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0097, \"times_seen\": 93.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.09399403978697682, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0399, \"times_seen\": 92.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.15764624719773943, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0641, \"times_seen\": 34.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.0991115757315421, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0049, \"times_seen\": 61.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.07315791815356804, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0953, \"times_seen\": 10.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"Y\", \"escape\": -0.007968292869726983, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0368, \"times_seen\": 28.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.007981570066198146, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -2.9356, \"times_seen\": 2.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.08359683689987149, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.1069, \"times_seen\": 32.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.855269641991134, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0076, \"times_seen\": 35.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.02728325332563628, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0609, \"times_seen\": 17.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": 0.031559707217952225, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0082, \"times_seen\": 17.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.012385834697318843, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0203, \"times_seen\": 31.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.011563396325924048, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -0.0365, \"times_seen\": 17.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.035734558665928735, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0746, \"times_seen\": 13.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.013097677569330455, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.1179, \"times_seen\": 14.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.03530204138721756, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0299, \"times_seen\": 46.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.005946044635295302, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0169, \"times_seen\": 10.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.005694221228819226, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0233, \"times_seen\": 10.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.09340374562820046, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -0.0905, \"times_seen\": 56.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.02150052465662247, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.066, \"times_seen\": 7.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 0.12292013149076944, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.102, \"times_seen\": 43.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -1.0028982349523083, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0822, \"times_seen\": 96.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.047424902625522666, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.012, \"times_seen\": 76.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.20729006863328148, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -0.0147, \"times_seen\": 84.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": -0.03824069557645322, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0732, \"times_seen\": 15.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": 0.7252315973529625, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.2595, \"times_seen\": 16.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.011637829718726426, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -2.1507, \"times_seen\": 3.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.01475542192150605, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.0939, \"times_seen\": 7.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.07163302409909943, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.0353, \"times_seen\": 12.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.014876612778125424, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.055, \"times_seen\": 5.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.0012535567729309786, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.1135, \"times_seen\": 5.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.0023094028841079742, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": 0.2737, \"times_seen\": 3.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.027455130878669503, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.0926, \"times_seen\": 8.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 0.029183409442983362, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.3805, \"times_seen\": 3.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.04650264619953823, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": 0.0867, \"times_seen\": 15.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.22991054442137107, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.1126, \"times_seen\": 72.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.06026533974984984, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.1314, \"times_seen\": 57.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.002044091132650861, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.0692, \"times_seen\": 25.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.02280613038448676, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.1399, \"times_seen\": 1.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.6493103066749548, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.3907, \"times_seen\": 4.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.2294792920992114, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": 0.007, \"times_seen\": 45.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.3575159461662971, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.1058, \"times_seen\": 39.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.7849631328046569, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.1244, \"times_seen\": 29.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.15302434583143562, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.0624, \"times_seen\": 41.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.017165860825693317, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.0345, \"times_seen\": 26.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.039622366993091566, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": -0.1187, \"times_seen\": 15.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.05318199498484862, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": -0.2799, \"times_seen\": 5.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.0030370885148060275, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": -3.1472, \"times_seen\": 1.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.010768018765072388, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.6806, \"times_seen\": 13.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.0017090802746442414, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.254, \"times_seen\": 3.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.016189641195971438, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.2097, \"times_seen\": 24.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.03852415488165552, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.1006, \"times_seen\": 8.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.0030236908450580104, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.1918, \"times_seen\": 1.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"escape\": 0.030511377260693962, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.548, \"times_seen\": 3.0}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0030099407629145163, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.0664, \"times_seen\": 1.0}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.008969651840466657, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.3599, \"times_seen\": 38.0}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.051403264334095033, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.3533, \"times_seen\": 31.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.005997974346030922, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.9919, \"times_seen\": 3.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.015067357674163201, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.289, \"times_seen\": 4.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -0.007603208999994841, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.2112, \"times_seen\": 1.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.24985854220625214, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.005938821108147679, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.8801, \"times_seen\": 1.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 1.3204780917161503, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.3971, \"times_seen\": 15.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.028201977360123268, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.0674, \"times_seen\": 13.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.0632255191526695, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.0208, \"times_seen\": 42.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": 0.0021023517146126765, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.4324, \"times_seen\": 8.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"escape\": 0.02279851911176338, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.226, \"times_seen\": 2.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": 0.06568956873032282, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -1.7952, \"times_seen\": 1.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.0042384176706819114, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -3.0861, \"times_seen\": 1.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.0012563454976071873, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.5755, \"times_seen\": 3.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.0030673680491299414, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.06399288918627753, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": 0.0225, \"times_seen\": 29.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.009402575725981131, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -0.3297, \"times_seen\": 6.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.006007091735438009, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.1117, \"times_seen\": 4.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.006375881156706796, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -0.1038, \"times_seen\": 1.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.05198986454384391, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.2675, \"times_seen\": 8.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.0034152900863185292, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": 0.1361, \"times_seen\": 1.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.024347535489507854, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": 0.0575, \"times_seen\": 48.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.041198908888462296, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.1649, \"times_seen\": 19.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.020328612907316055, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.037, \"times_seen\": 6.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"V\", \"escape\": 0.006956726061342008, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.0978, \"times_seen\": 8.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.006899968280076979, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -2.8702, \"times_seen\": 2.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"F\", \"escape\": -0.00600956812562213, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.3883, \"times_seen\": 10.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.04459162497059438, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.1072, \"times_seen\": 27.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.08415052415703507, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.2079, \"times_seen\": 37.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": 0.020518862506863002, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -0.0532, \"times_seen\": 7.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.0227650287124872, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -0.0278, \"times_seen\": 5.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.014305887259028207, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -0.0187, \"times_seen\": 20.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.05059518445083301, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.0631, \"times_seen\": 40.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.010545037787732034, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -2.5379, \"times_seen\": 4.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.0016445456158777235, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.5758, \"times_seen\": 18.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.2856777362866374, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.2049, \"times_seen\": 34.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.039400820033183015, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -1.3312, \"times_seen\": 30.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": 1.1471949407693882, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -1.0518, \"times_seen\": 6.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.049986115886698844, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.272, \"times_seen\": 37.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.005703610143185011, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.7768, \"times_seen\": 18.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.003769738216781316, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": 0.0215, \"times_seen\": 5.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.004010435677675317, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.5077, \"times_seen\": 1.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.07959512388051283, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.1285, \"times_seen\": 48.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.002737344656744999, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.8816, \"times_seen\": 2.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.07854547040280276, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.1565, \"times_seen\": 10.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.009050676762346369, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.5376, \"times_seen\": 5.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.01284438657218831, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.0026, \"times_seen\": 2.0}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.04050968974934922, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -2.604, \"times_seen\": 3.0}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.014129114235558448, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -0.4407, \"times_seen\": 17.0}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.09483315479917277, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": 0.1596, \"times_seen\": 22.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.011210952011250656, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.8345, \"times_seen\": 5.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 1.6385054130268222, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.0186, \"times_seen\": 8.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.035149590209893895, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -3.0628, \"times_seen\": 1.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.02440136853398869, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.9047, \"times_seen\": 8.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.0039454275291655174, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -2.8821, \"times_seen\": 2.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.007812666919236367, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.9254, \"times_seen\": 7.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.0045153957977545015, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.1495, \"times_seen\": 13.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.03893735524629768, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.2832, \"times_seen\": 10.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0007405573142023367, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.0198, \"times_seen\": 10.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.22502196149012813, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": -2.5621, \"times_seen\": 3.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.004204555768991973, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.016344333423777967, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.2369, \"times_seen\": 6.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.013063352617785061, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -1.1404, \"times_seen\": 2.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": 0.01855821523980575, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.0428, \"times_seen\": 8.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.02838291804558902, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.1839, \"times_seen\": 13.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -1.849707739795898e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.1017, \"times_seen\": 7.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.012364437768359087, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -2.2104, \"times_seen\": 1.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.006730999379283, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -1.7772, \"times_seen\": 2.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.019272312964981216, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": 0.0871, \"times_seen\": 41.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.018141583941412995, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -0.6036, \"times_seen\": 9.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.005784676330968744, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -2.0079, \"times_seen\": 2.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.05274406514802985, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.0587, \"times_seen\": 13.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": 0.0060814049003157225, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -2.2279, \"times_seen\": 4.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.02146609294230486, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.5216, \"times_seen\": 1.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0038952871389531375, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.0027686602545994275, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -2.205, \"times_seen\": 1.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.12059651970946153, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.4854, \"times_seen\": 23.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.00800971550983163, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.5363, \"times_seen\": 7.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.005451889153169325, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.0399, \"times_seen\": 6.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.005678933488244075, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.022, \"times_seen\": 12.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.14983024117712299, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.0907, \"times_seen\": 20.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.07837056207769291, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.0742, \"times_seen\": 66.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": 0.0029270509140923665, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.05932228033715542, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.0644, \"times_seen\": 35.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.010020799658618532, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.1804, \"times_seen\": 3.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.0026469108256537395, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.3515, \"times_seen\": 3.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.005530221704139407, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": 0.3023, \"times_seen\": 5.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0011565164180839245, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.158, \"times_seen\": 6.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.00392242204632013, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.1816, \"times_seen\": 10.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": 0.015297696740655639, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.5737, \"times_seen\": 7.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.05587848182599705, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.5124, \"times_seen\": 18.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.00431041268414455, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.5122, \"times_seen\": 4.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.005814499624269086, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.3142, \"times_seen\": 6.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.006314575631910897, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.6094, \"times_seen\": 3.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.006253441809429037, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.9367, \"times_seen\": 3.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.011872398656519423, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.1027, \"times_seen\": 1.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.004460012401376544, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -1.1641, \"times_seen\": 11.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.09317353305584407, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": -0.3641, \"times_seen\": 9.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.023234407051627073, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": 0.0723, \"times_seen\": 35.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.008014677671569463, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": 0.0307, \"times_seen\": 10.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.025012457115003855, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": -0.7634, \"times_seen\": 15.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.0026210128487621554, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": -2.1294, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.0008836864136799646, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -2.5283, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"H\", \"escape\": -0.002771902757183896, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -0.9999, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.010626687737121906, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": 0.3094, \"times_seen\": 2.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.0025065736082218234, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": 0.0603, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.00040078529175673934, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -2.4581, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.026367634311468095, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -0.5039, \"times_seen\": 7.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.0009732444440531958, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.1206, \"times_seen\": 10.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.08393725917106949, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": -0.2387, \"times_seen\": 42.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.003587313099806153, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": -0.5709, \"times_seen\": 2.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.011899897995053494, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.375, \"times_seen\": 6.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.013377853122907906, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.0237, \"times_seen\": 5.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": 0.009420041084260571, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": -0.7594, \"times_seen\": 5.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.018199057691909888, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": 0.0436, \"times_seen\": 17.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.013509184267936045, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": 0.0117, \"times_seen\": 19.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.002069745817642479, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.256, \"times_seen\": 37.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.5450344964622841, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.5928, \"times_seen\": 21.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.18570811028895393, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.2422, \"times_seen\": 42.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.002728822709640369, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.1861, \"times_seen\": 5.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": 0.016641511767984077, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.6825, \"times_seen\": 2.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.007841963230082275, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -2.4039, \"times_seen\": 2.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.02824642176475369, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -1.7855, \"times_seen\": 7.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.02072866433367104, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -0.3032, \"times_seen\": 10.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.00038773760638998323, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -1.3855, \"times_seen\": 1.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.0011859713694114288, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.004562075568314656, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -2.0516, \"times_seen\": 1.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.006239913384028278, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -0.4047, \"times_seen\": 30.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.1367438730921199, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -0.6318, \"times_seen\": 42.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.0210580855406024, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": 0.0028, \"times_seen\": 20.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": 0.0210963702681933, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -2.377, \"times_seen\": 1.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0194284211130053, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -0.9491, \"times_seen\": 11.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": 0.01902943579746822, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -0.7449, \"times_seen\": 5.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.006887462510369858, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": 0.0764, \"times_seen\": 46.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.07684381811079599, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -0.3648, \"times_seen\": 35.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.009570968344697334, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -2.4112, \"times_seen\": 4.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": -0.016588650032272032, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -1.5933, \"times_seen\": 3.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": -0.003871888734573323, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -2.7813, \"times_seen\": 1.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.0021497664821794674, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.8712, \"times_seen\": 1.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.002633282241387584, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.016930413291193255, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.6977, \"times_seen\": 5.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.0001397778080776002, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.4834, \"times_seen\": 1.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.0012358856894005693, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -1.8107, \"times_seen\": 1.0}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.05110260267962502, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.8773, \"times_seen\": 2.0}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -1.356821886702219, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.06807323970914285, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.942, \"times_seen\": 4.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.03585646388849603, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -0.5923, \"times_seen\": 6.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.02098897965874673, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": 0.0892, \"times_seen\": 21.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.036228206122880115, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -1.2288, \"times_seen\": 4.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.015044989647837143, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -0.0029, \"times_seen\": 65.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -2.5682746421901306, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -0.4092, \"times_seen\": 99.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.05012108738579252, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -1.2201, \"times_seen\": 29.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.004848903612548683, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -0.1435, \"times_seen\": 20.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.05074196623821532, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -0.566, \"times_seen\": 18.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.010363866527582682, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -2.7275, \"times_seen\": 5.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.016349608060017062, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.013051336669796555, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -1.4644, \"times_seen\": 2.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": 0.008715847378894116, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -0.4162, \"times_seen\": 4.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": 0.006940017386462903, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -0.4328, \"times_seen\": 12.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.014773779619093678, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -1.797, \"times_seen\": 6.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -9.727792442114953e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -0.8142, \"times_seen\": 5.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.06957664229362921, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -0.7427, \"times_seen\": 15.0}, {\"site\": 292, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.01132868590632594, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -2.5027, \"times_seen\": 4.0}, {\"site\": 292, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0037338219795442513, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -1.8602, \"times_seen\": 1.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.005189783729936044, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -0.0809, \"times_seen\": 7.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0018540642541327401, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -1.0336, \"times_seen\": 6.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.0031473086533008498, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -1.3293, \"times_seen\": 1.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.002241383861307491, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 294, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.006190656096064576, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -2.9686, \"times_seen\": 4.0}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.01893776350716603, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.4414, \"times_seen\": 3.0}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.0024216209522161156, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.3102, \"times_seen\": 1.0}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": 0.008881150481879907, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.7989, \"times_seen\": 4.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.09356500895660123, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -0.5588, \"times_seen\": 44.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -1.479985917306907, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -0.0909, \"times_seen\": 46.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.004377794535316065, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -2.6088, \"times_seen\": 1.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.007311662678055297, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -2.7361, \"times_seen\": 2.0}, {\"site\": 297, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.016184196312061434, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -0.957, \"times_seen\": 8.0}, {\"site\": 297, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.5338891921896973, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -0.3747, \"times_seen\": 19.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"E\", \"escape\": -0.32596111092798913, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -1.8786, \"times_seen\": 2.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.004621535341207188, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -1.2026, \"times_seen\": 1.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": -0.00947775197355026, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -2.9714, \"times_seen\": 1.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.02639708788493754, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -1.9379, \"times_seen\": 4.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.01375395338464274, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -1.499, \"times_seen\": 2.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.011444098811376034, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -1.3649, \"times_seen\": 2.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.00010397451802228616, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -2.7225, \"times_seen\": 1.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.02657067470297237, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -0.1582, \"times_seen\": 10.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.00013759032740946772, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -1.4017, \"times_seen\": 8.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.06657641172973772, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.2625, \"times_seen\": 11.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.8281187581874698, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.3669, \"times_seen\": 11.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.018399228327960895, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -2.7576, \"times_seen\": 6.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.00112986805142727, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.479, \"times_seen\": 3.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.016281227883853062, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.4159, \"times_seen\": 7.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.014954959925793163, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.2879, \"times_seen\": 6.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.027560222757279814, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.0628, \"times_seen\": 6.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.0034693692862531552, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.158, \"times_seen\": 1.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.011310177396430924, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -0.1786, \"times_seen\": 3.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.008172396551952626, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -1.4452, \"times_seen\": 1.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.003690355500558446, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -2.3834, \"times_seen\": 1.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.008960423113523536, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -1.1237, \"times_seen\": 4.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.01834668803293758, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -0.0342, \"times_seen\": 6.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.008004754111259586, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -0.6279, \"times_seen\": 1.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.3496333274355885, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": 0.0613, \"times_seen\": 24.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 1.3311204030504367, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -1.6708, \"times_seen\": 9.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.014260283438598673, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -0.909, \"times_seen\": 4.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.038488759918387745, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.3108, \"times_seen\": 39.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.016984506940957836, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -1.2485, \"times_seen\": 14.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.23255289530845136, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.0379, \"times_seen\": 21.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.03378989673830826, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1194, \"times_seen\": 21.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.004763939251463702, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.0637, \"times_seen\": 20.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": -0.02161467476138454, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.2287, \"times_seen\": 20.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": 0.18393138365130424, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1652, \"times_seen\": 56.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.03244007755168747, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1408, \"times_seen\": 65.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.01681560747170321, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.0408476385208394, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.5884, \"times_seen\": 31.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.028093979903326387, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.2332, \"times_seen\": 14.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.007699286889162697, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.3637, \"times_seen\": 43.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.0064446779838743746, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -2.9172, \"times_seen\": 5.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.0228617677693033, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1465, \"times_seen\": 13.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.016429494612870722, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.4913, \"times_seen\": 48.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.383070598097823, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1091, \"times_seen\": 45.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": 0.07368922981349792, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.151, \"times_seen\": 28.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": 0.008051104043335245, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1403, \"times_seen\": 7.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": 0.01598551525751593, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1142, \"times_seen\": 29.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.006922766126251495, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -3.0197, \"times_seen\": 1.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.0044818429894329746, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -2.9654, \"times_seen\": 1.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.027688234618973705, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -0.2195, \"times_seen\": 20.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.41806409399373046, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -0.2644, \"times_seen\": 38.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.017765481883915666, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -1.6965, \"times_seen\": 6.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.0068670825680488224, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": 0.0088, \"times_seen\": 6.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.6625839335303556, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": 0.2651, \"times_seen\": 15.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.018593043406613153, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.2689, \"times_seen\": 12.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.10780208412956568, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.3164, \"times_seen\": 43.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.010296109581266612, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.3346, \"times_seen\": 10.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -0.016616810807632217, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.4373, \"times_seen\": 5.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.005680416672263605, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.4553, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.007840449021727853, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -1.2932, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.008483678609484839, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -3.1432, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.004425075233433666, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.8806192896238245, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -0.8163, \"times_seen\": 50.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.0009701753088877548, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -2.4752, \"times_seen\": 4.0}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.000554245621562935, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.7756, \"times_seen\": 1.0}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -0.003988405015435622, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.0038372734116839157, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.9695, \"times_seen\": 2.0}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0034761658516423324, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -1.3805, \"times_seen\": 1.0}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.012160933016784864, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -0.8374, \"times_seen\": 2.0}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.04201892164063368, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -0.7195, \"times_seen\": 30.0}, {\"site\": 310, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.028881580991793086, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -1.1574, \"times_seen\": 18.0}, {\"site\": 310, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.0017398220395591355, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -1.9558, \"times_seen\": 1.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.03360548691805489, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": 0.176, \"times_seen\": 23.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 1.118975633713472, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.7858, \"times_seen\": 67.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.026358429511159655, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -1.0693, \"times_seen\": 16.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": -0.0019293791636728686, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -2.9646, \"times_seen\": 1.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.009817225339567276, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.3635, \"times_seen\": 15.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": -0.6475253752160606, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.4081, \"times_seen\": 6.0}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.020829823273076024, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -0.6353, \"times_seen\": 53.0}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.012512309504204648, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -0.189, \"times_seen\": 6.0}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.017713144628835928, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -1.8127, \"times_seen\": 2.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.6720299500695108, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.3363, \"times_seen\": 6.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.006875093759813005, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -1.5098, \"times_seen\": 17.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.0059914653820181745, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.2965, \"times_seen\": 1.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.024663081280450878, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -2.2771, \"times_seen\": 1.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.08423632930730443, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.6941, \"times_seen\": 34.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.30440045429388773, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.7144, \"times_seen\": 14.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.02058936649368398, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -0.6442, \"times_seen\": 6.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.011477317718215311, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -0.6906, \"times_seen\": 15.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.08196481951846042, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": 0.397, \"times_seen\": 5.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.0022972963613521508, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -1.267, \"times_seen\": 13.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.0026820884460305497, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -3.0955, \"times_seen\": 1.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.015142086073737961, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -2.3483, \"times_seen\": 3.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.017099123003352434, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -2.7033, \"times_seen\": 2.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.007309255408028781, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -1.9318, \"times_seen\": 5.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.002823534210664473, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -3.0863, \"times_seen\": 1.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.0009979869255225436, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -0.6018, \"times_seen\": 6.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.8881743742057827, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.9537, \"times_seen\": 2.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.016010445249423775, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.6552, \"times_seen\": 3.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.009744628795984893, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.9195, \"times_seen\": 3.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.004972730864681855, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.8689, \"times_seen\": 2.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.026772073070389847, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.7064, \"times_seen\": 10.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.04510464727935873, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.8559, \"times_seen\": 34.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.45462179863825225, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.9803, \"times_seen\": 40.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.002771469657353231, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -1.5735, \"times_seen\": 1.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.0015901728875351265, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.7449, \"times_seen\": 1.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.00947706357078037, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.9377, \"times_seen\": 1.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.01994346701426504, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.5327, \"times_seen\": 10.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.007205538586615754, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.8911, \"times_seen\": 9.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.03812495298298977, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.0811, \"times_seen\": 12.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": -0.015704195556157482, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.9701, \"times_seen\": 6.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.0020087262569726348, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -1.0749, \"times_seen\": 5.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.0024781038405606404, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.2258, \"times_seen\": 8.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": -0.0072803403826660305, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.4794, \"times_seen\": 2.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.00398879459855542, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -2.6762, \"times_seen\": 1.0}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.03280805017940955, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -0.2729, \"times_seen\": 4.0}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.02086955101635422, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -1.9086, \"times_seen\": 5.0}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.012837549787041456, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.2576, \"times_seen\": 4.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.07936900021189511, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.3162, \"times_seen\": 10.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": 0.00040651788549521395, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.7671, \"times_seen\": 3.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.7971195511225321, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.4383, \"times_seen\": 60.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.02627328841122965, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.5786, \"times_seen\": 14.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": 0.026089107817187502, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.137, \"times_seen\": 12.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.008668480396345159, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.6717, \"times_seen\": 5.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.01437928641714472, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.1638, \"times_seen\": 5.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.04366213121305215, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": 0.0029, \"times_seen\": 15.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.016506322034726885, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.3656, \"times_seen\": 7.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.005207437085711092, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.5403, \"times_seen\": 58.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": -0.015409783300626806, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.5867, \"times_seen\": 7.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.20276474357399904, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.0984, \"times_seen\": 34.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"T\", \"escape\": 0.014839181085967924, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.1734, \"times_seen\": 2.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.00020382443676643993, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.7978, \"times_seen\": 10.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.006261252176697717, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.6202, \"times_seen\": 6.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.001344807593931953, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -1.2264, \"times_seen\": 15.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.014174868666287954, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.7689, \"times_seen\": 2.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.009723460543615186, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -2.213, \"times_seen\": 3.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.005262320164600677, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -1.5172, \"times_seen\": 2.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0509949713084941, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.3715, \"times_seen\": 21.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.009304389121627012, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.9655, \"times_seen\": 12.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.04656007120893606, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.9614, \"times_seen\": 8.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.025441813650345594, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -1.4178, \"times_seen\": 1.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.005323879125391807, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -1.7148, \"times_seen\": 1.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0242110414733319, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -1.0998, \"times_seen\": 1.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.6316423741070261, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -0.3931, \"times_seen\": 9.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0013520894741383032, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.7275, \"times_seen\": 3.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.0035853675824309927, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -2.6838, \"times_seen\": 2.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.004845361414404881, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -1.3291, \"times_seen\": 3.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.4301521514446786, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.1757, \"times_seen\": 21.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.001359942846237777, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.3755, \"times_seen\": 11.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.02916608931712609, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.9679, \"times_seen\": 6.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.013267449998193112, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.8286, \"times_seen\": 4.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.014024260656784419, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.836, \"times_seen\": 2.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"D\", \"escape\": -0.009510506791697513, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.8843, \"times_seen\": 2.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.008670541372025012, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.1289, \"times_seen\": 3.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.002733512515921898, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.6076, \"times_seen\": 5.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.00407523673979524, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.5307, \"times_seen\": 1.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.01907823066217245, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -1.4592, \"times_seen\": 4.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.009830236123862045, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -0.6351, \"times_seen\": 3.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.0005166341683269791, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -0.4705, \"times_seen\": 1.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.003670658461774062, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -0.0063, \"times_seen\": 2.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.008164019315057456, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -0.7972, \"times_seen\": 3.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": -0.0068917297468094295, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -2.3054, \"times_seen\": 2.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.03315767130517623, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -2.0515, \"times_seen\": 13.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.012372713918013409, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -0.7268, \"times_seen\": 9.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.028500707372308122, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -0.5332, \"times_seen\": 8.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.029406907007748062, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.6479, \"times_seen\": 7.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"E\", \"escape\": -0.035413077730278616, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.8157, \"times_seen\": 6.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.020896272680219267, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.4035, \"times_seen\": 4.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.03007360651052851, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.5622, \"times_seen\": 9.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -3.533479848494647e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.3715, \"times_seen\": 2.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.02678543214685706, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.8968, \"times_seen\": 10.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.0069018567084294345, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -1.143, \"times_seen\": 2.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.0023200189660705964, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.7836, \"times_seen\": 6.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.0010149921122153266, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -1.0754, \"times_seen\": 2.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.002482785926919619, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -0.7585, \"times_seen\": 8.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.00818332035341912, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -0.3776, \"times_seen\": 8.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.01606635219850908, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": 0.2852, \"times_seen\": 11.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.2701744059561413, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.7535, \"times_seen\": 12.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.013043331374300027, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.5184, \"times_seen\": 2.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.04581249492367082, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.1133, \"times_seen\": 19.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.02652587181897442, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.5261, \"times_seen\": 6.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.007023724392793254, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.2929, \"times_seen\": 3.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.017526461342255235, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.6052, \"times_seen\": 3.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.017516155754486937, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.9414, \"times_seen\": 13.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.0019242332142696235, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": 0.1851, \"times_seen\": 1.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.024503849099319575, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.0236, \"times_seen\": 9.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.01603350296312077, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.1305, \"times_seen\": 5.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.00482300724040307, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -0.3008, \"times_seen\": 10.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.05767109229839241, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -0.0467, \"times_seen\": 13.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.01234277548816773, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.02533119375257298, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.1552, \"times_seen\": 9.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.09015948151811638, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -0.6434, \"times_seen\": 15.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": -0.030067570203983936, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.1562, \"times_seen\": 6.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.014190876741144083, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.5329, \"times_seen\": 11.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.00969554664756581, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.1499, \"times_seen\": 2.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.03825781405772886, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.3107, \"times_seen\": 44.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0031562014801922514, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.00033917567754761794, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.1127, \"times_seen\": 3.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.021817919865658918, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.1485, \"times_seen\": 4.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.0027411872232667054, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.1033, \"times_seen\": 5.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.03669567923847407, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.1043, \"times_seen\": 10.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.0018454468107705847, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -3.0902, \"times_seen\": 1.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"T\", \"escape\": -0.003560024247499164, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -0.5053, \"times_seen\": 1.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": -0.002802881169744816, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -3.0351, \"times_seen\": 1.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.0021221574123160103, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -3.0805, \"times_seen\": 1.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 0.014293090564346689, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.5521, \"times_seen\": 7.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.04105821836582053, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -1.2878, \"times_seen\": 24.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.021174324962792167, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.5949, \"times_seen\": 5.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.02492121271840118, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.0135, \"times_seen\": 4.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.022238460302163997, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.2692, \"times_seen\": 29.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.04747398639653623, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.9523, \"times_seen\": 26.0}, {\"site\": 335, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.0028599882438692377, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -1.541, \"times_seen\": 1.0}, {\"site\": 335, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.13339466177444176, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -0.2003, \"times_seen\": 16.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.3031928645705534, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.0839, \"times_seen\": 90.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.027136188982018278, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -2.0663, \"times_seen\": 14.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.41866927929324155, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1538, \"times_seen\": 47.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -0.14247176139796516, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.3194, \"times_seen\": 20.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.39978767245506225, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2671, \"times_seen\": 97.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.003635027608631198, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1039, \"times_seen\": 23.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.3724588863300518, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.0518, \"times_seen\": 28.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": 0.08141663012040784, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2848, \"times_seen\": 20.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.1874788460580499, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1498, \"times_seen\": 72.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.04152702622498596, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.024, \"times_seen\": 19.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.28988881342616585, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.1268, \"times_seen\": 37.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": -0.001220724960553027, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.5614, \"times_seen\": 56.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.02229115779085545, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.0728, \"times_seen\": 24.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.32077138951642037, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2837, \"times_seen\": 60.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.18751198407405034, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.143, \"times_seen\": 99.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.8557359423576718, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.0781, \"times_seen\": 62.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.08762406861285739, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1474, \"times_seen\": 83.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": 0.4864306080689641, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.011, \"times_seen\": 32.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.09085857888206485, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2646, \"times_seen\": 30.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": -0.005507769638387322, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -2.9687, \"times_seen\": 2.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.008140500080560048, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.5449, \"times_seen\": 10.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.10974557314400996, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.3, \"times_seen\": 42.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.0074626282674258105, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -1.2106, \"times_seen\": 11.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.06180873894976427, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.3866, \"times_seen\": 82.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.027502625706546064, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.4231, \"times_seen\": 22.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": -0.03808416343244957, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.356, \"times_seen\": 13.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.011064192303188029, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.9399, \"times_seen\": 10.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.005222458159045689, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -0.1591, \"times_seen\": 9.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.02099904007031276, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": 0.2472, \"times_seen\": 25.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0070151787855620195, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": 0.2113, \"times_seen\": 5.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.040631758643118056, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -0.6083, \"times_seen\": 9.0}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.03273897012761541, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -0.9156, \"times_seen\": 26.0}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.007608616129351183, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.5995, \"times_seen\": 1.0}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.014814289713396713, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.1252, \"times_seen\": 4.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.062438030079178135, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -2.1705, \"times_seen\": 5.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.0007524169225341078, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -1.0153, \"times_seen\": 6.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.015409271060437128, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -1.1804, \"times_seen\": 9.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.010319100310334632, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -1.4042, \"times_seen\": 4.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.019892565384545462, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -1.243, \"times_seen\": 8.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.008003701184819688, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.3353, \"times_seen\": 7.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.041008290752862324, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.2672, \"times_seen\": 36.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.018704507239933228, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.5728, \"times_seen\": 65.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.03381730194109593, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.4456, \"times_seen\": 42.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.018802508409933107, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -0.6463, \"times_seen\": 5.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.006589296773450059, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -1.1581, \"times_seen\": 2.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.0075634801280401115, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -2.2256, \"times_seen\": 3.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.012782334090803742, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -0.1618, \"times_seen\": 16.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.16806024489540977, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.8701, \"times_seen\": 13.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -1.4059324782469826, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.1825, \"times_seen\": 38.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.29566684622201117, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": 0.0144, \"times_seen\": 40.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.0019212634387745697, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.433, \"times_seen\": 3.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": -0.5894783924505985, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.0793, \"times_seen\": 21.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -1.7543773887207017, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.0179, \"times_seen\": 36.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.008635312171238215, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.0394, \"times_seen\": 46.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.018957253057449247, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.9264, \"times_seen\": 1.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.020251003753705848, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -1.2666, \"times_seen\": 11.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.0010513696763557773, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -0.8318, \"times_seen\": 1.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.007714735978355819, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.7247, \"times_seen\": 1.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.005463037385282119, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": 0.286, \"times_seen\": 15.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.08975367430324935, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -0.1404, \"times_seen\": 54.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.036341737810895405, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -1.4223, \"times_seen\": 66.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.047519508077566816, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.0791, \"times_seen\": 18.0}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.03683874839182357, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.3199, \"times_seen\": 7.0}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.003557255011023538, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.6787, \"times_seen\": 1.0}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.013136340772851396, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -0.9486, \"times_seen\": 42.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.006174027841433433, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.7213, \"times_seen\": 6.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.0019018179622841166, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.8082, \"times_seen\": 1.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.005493218990066179, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.01211053799697881, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.448, \"times_seen\": 3.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.007777443247224245, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -0.2001, \"times_seen\": 8.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.6943201720921399, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -1.3139, \"times_seen\": 36.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.013178851558198078, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -1.8702, \"times_seen\": 2.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"M\", \"escape\": 0.009355034208473549, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -1.7304, \"times_seen\": 2.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.017122599263627643, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -1.6949, \"times_seen\": 5.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.009884156754766765, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -1.3905, \"times_seen\": 4.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.011440072680236973, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -0.151, \"times_seen\": 3.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.12893566695730171, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -0.3134, \"times_seen\": 29.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.0384950259292899, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -1.7921, \"times_seen\": 11.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.036662738107415827, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -2.0636, \"times_seen\": 12.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.015065779014690707, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -1.6642, \"times_seen\": 4.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": -0.0037670625375761276, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -1.2602, \"times_seen\": 3.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.00795535237488435, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -2.2285, \"times_seen\": 4.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": -0.012256785277081869, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -2.6704, \"times_seen\": 14.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.175625697986969, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.0623, \"times_seen\": 14.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"E\", \"escape\": -0.0029035733693209263, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.147, \"times_seen\": 2.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.0024737512612819264, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.4126, \"times_seen\": 1.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.009196070835116043, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.0631, \"times_seen\": 23.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.7121049201510732, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.0079, \"times_seen\": 37.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.06674226322260186, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.0514, \"times_seen\": 17.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.015658432203260134, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.0793, \"times_seen\": 12.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.003230790239090764, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -1.1562, \"times_seen\": 9.0}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.1412421352391136, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.9596, \"times_seen\": 2.0}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.010108158226852513, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.7349, \"times_seen\": 2.0}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.005824906977187102, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.9759, \"times_seen\": 1.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.0023486169709305642, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -0.879, \"times_seen\": 8.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.026766011406280217, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.0611, \"times_seen\": 16.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.15657768729922145, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -0.716, \"times_seen\": 43.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.006436579704669991, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.1857, \"times_seen\": 6.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.18328077117726346, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -0.0135, \"times_seen\": 63.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.25019410984506285, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.1867, \"times_seen\": 5.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.05395746141579962, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.5066, \"times_seen\": 8.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.7121362146891965, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -1.2627, \"times_seen\": 12.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.026048837770139388, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": 0.0912, \"times_seen\": 8.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.02873263056156098, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": 0.1788, \"times_seen\": 61.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.012495722967085272, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.1804, \"times_seen\": 9.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.026189431127365995, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.1978, \"times_seen\": 6.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.006569820716479092, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.0626, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"E\", \"escape\": -0.0035879207893591354, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -2.5714, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.023754946988200375, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -0.1098, \"times_seen\": 5.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.01553644229063095, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -2.9698, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.0032634911670726607, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -2.0747, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.015305385046324047, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -1.0623, \"times_seen\": 5.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.010205783509146624, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.05378202061747999, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -1.0958, \"times_seen\": 40.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.09847838739735383, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.7569, \"times_seen\": 17.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.0038607722284610046, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -1.8765, \"times_seen\": 1.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.14473433305946376, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.2229, \"times_seen\": 57.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.06037931711790729, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.2929, \"times_seen\": 38.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.30993738069678806, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.1307, \"times_seen\": 15.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": -0.013833808220903908, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -1.1934, \"times_seen\": 3.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.05057828914493578, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": 0.1485, \"times_seen\": 20.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.006056226383502698, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -1.5839, \"times_seen\": 9.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": -0.010393324801286654, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -2.5769, \"times_seen\": 1.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.009884313302311678, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -0.6761, \"times_seen\": 10.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.005112918443738397, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -2.6163, \"times_seen\": 8.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.023678684690067973, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -0.9013, \"times_seen\": 11.0}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.01071569656599664, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.0623, \"times_seen\": 1.0}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.12516973310319537, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.0611, \"times_seen\": 2.0}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": 0.5618207988885064, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.0774, \"times_seen\": 2.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.003745647606724062, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -1.5445, \"times_seen\": 1.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.022346424566716157, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -2.0064, \"times_seen\": 8.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.004380789384020093, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": 0.3073, \"times_seen\": 19.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.024369634527778926, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -0.6073, \"times_seen\": 8.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.03226893452351746, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -0.4763, \"times_seen\": 9.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.00813117495065162, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.015073054124343729, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": 0.1011, \"times_seen\": 4.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.026941432580874995, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -0.5295, \"times_seen\": 7.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.09786228568058365, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -0.8575, \"times_seen\": 30.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -1.0837572817000323, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -0.3613, \"times_seen\": 15.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.010994331941035088, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -1.3617, \"times_seen\": 2.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.15748292433267863, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.1651, \"times_seen\": 4.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.02633765679141211, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -0.5487, \"times_seen\": 24.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.00837526771592373, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.0705, \"times_seen\": 3.0}, {\"site\": 362, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.08628577431333043, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": 0.3737, \"times_seen\": 28.0}, {\"site\": 362, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -0.008782649016149637, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.4808, \"times_seen\": 2.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0775573508320071, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -0.4622, \"times_seen\": 7.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.00464436361516928, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -1.6583, \"times_seen\": 4.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.011413756093917383, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -2.019, \"times_seen\": 4.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.0034517256845642778, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -1.9635, \"times_seen\": 2.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.00033649671599359605, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": 0.0449, \"times_seen\": 1.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.006844843839917941, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -1.8807, \"times_seen\": 2.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.054435079048260296, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.138, \"times_seen\": 30.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.0143163475147423, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.7208, \"times_seen\": 3.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.4938210828319854, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.2354, \"times_seen\": 19.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.0034777434125713483, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.2734, \"times_seen\": 25.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.023508018523297723, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.1391, \"times_seen\": 13.0}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.01377395924551021, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -0.39, \"times_seen\": 13.0}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.3514859373850603, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": 0.0653, \"times_seen\": 99.0}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.0007621062472075647, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -1.7436, \"times_seen\": 2.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.01805298653734886, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -1.9688, \"times_seen\": 31.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.5892110961699107, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -0.9627, \"times_seen\": 59.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.039877638109291985, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": 0.1515, \"times_seen\": 192.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -5.4413773650249674e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -0.013, \"times_seen\": 2.0}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.10731311768566333, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.0556, \"times_seen\": 59.0}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.03454899067488066, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.1043, \"times_seen\": 52.0}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.045260210126680356, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.0551, \"times_seen\": 28.0}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.03706501594365838, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": -0.1012, \"times_seen\": 119.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": -0.0959458404608368, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.4914, \"times_seen\": 69.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.019493379257077795, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -1.1983, \"times_seen\": 29.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": 0.04152556741904417, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.3662, \"times_seen\": 26.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": 0.08702655251809985, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.5704, \"times_seen\": 46.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.3726819989352877, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.3186, \"times_seen\": 59.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": 0.411751858239629, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.4595, \"times_seen\": 68.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.042649308308424824, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.1037, \"times_seen\": 49.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.04640010199363787, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.0442, \"times_seen\": 29.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": 0.7537341694069462, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.6695, \"times_seen\": 55.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.18941260153953823, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.0595, \"times_seen\": 69.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": 0.4828235064737393, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.284, \"times_seen\": 25.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.10619565739692395, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -1.429, \"times_seen\": 156.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.03643113029003718, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.2541, \"times_seen\": 84.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.22264693447657266, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.63, \"times_seen\": 155.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.8997371590709716, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.2365, \"times_seen\": 113.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.148397967468069, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.5176, \"times_seen\": 84.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.08172487579442582, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.1334, \"times_seen\": 87.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.013794520760611238, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.4396, \"times_seen\": 66.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.03331060203638776, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"*\", \"escape\": -0.026122851215614435, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -2.6155, \"times_seen\": 10.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.000588467409942827, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.1472, \"times_seen\": 2.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.0321697534943299, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.4262, \"times_seen\": 29.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.004469023279468345, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.1825482263401624, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.3405, \"times_seen\": 66.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.0375812627913119, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.0329, \"times_seen\": 37.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": -0.00010348898741147907, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.1683, \"times_seen\": 1.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.012436446218812805, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.2148, \"times_seen\": 49.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"C\", \"escape\": -0.010333368335905795, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.8573, \"times_seen\": 4.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"D\", \"escape\": 0.6673907047851534, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": 0.0955, \"times_seen\": 16.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"E\", \"escape\": 0.0002862221047128221, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": 0.0605, \"times_seen\": 20.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"F\", \"escape\": -0.4090255781715872, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.1184, \"times_seen\": 17.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": 0.30671365835030334, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1726, \"times_seen\": 42.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -2.324626479342614, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1823, \"times_seen\": 43.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"I\", \"escape\": 0.00023608779937688042, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.1776, \"times_seen\": 12.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"K\", \"escape\": -0.12738907168246713, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.9567, \"times_seen\": 22.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.2712003250331756, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.0822, \"times_seen\": 61.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": -0.0028788751841528105, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.4088, \"times_seen\": 13.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"N\", \"escape\": -0.5087319101976367, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.013605403007698746, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1828, \"times_seen\": 29.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.5517933451654828, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.9029, \"times_seen\": 68.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.013016171508915396, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.0398, \"times_seen\": 92.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.16516165509023878, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1946, \"times_seen\": 67.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": -0.03177982995116238, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.8733, \"times_seen\": 24.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"W\", \"escape\": 3.579829412066608e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.2685, \"times_seen\": 16.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"Y\", \"escape\": 0.014094569753912775, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.5623, \"times_seen\": 18.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"*\", \"escape\": -0.015151246543872371, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -2.9613, \"times_seen\": 2.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.029288217566648306, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.1664, \"times_seen\": 3.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.8735496687410343, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.0949, \"times_seen\": 59.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.05657202286090374, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.1855, \"times_seen\": 17.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.01929471822974083, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.019931729524262743, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": 0.397, \"times_seen\": 4.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"A\", \"escape\": 0.31175039597444626, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.1646, \"times_seen\": 82.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.34170781935913125, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.0937, \"times_seen\": 58.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"D\", \"escape\": 0.09043836160824348, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 48.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"E\", \"escape\": 0.7334672589222287, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"G\", \"escape\": 0.20097293237293284, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.1997, \"times_seen\": 42.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"H\", \"escape\": 0.20117173158120502, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.3194, \"times_seen\": 35.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.14725968895934655, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.0579, \"times_seen\": 84.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"K\", \"escape\": -0.016033144166032326, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.7091, \"times_seen\": 25.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.05600636956564844, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.2194, \"times_seen\": 153.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"M\", \"escape\": -0.01899301440626008, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.2135, \"times_seen\": 29.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"N\", \"escape\": 0.04477249186972488, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.3347, \"times_seen\": 46.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"P\", \"escape\": -0.7755222731337988, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.3061, \"times_seen\": 81.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"Q\", \"escape\": 0.002350155462727016, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.397, \"times_seen\": 23.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"R\", \"escape\": 0.23068611836739406, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -1.2678, \"times_seen\": 47.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.3696951133127017, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 227.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"T\", \"escape\": 0.21882315715514616, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 106.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.3086787274781873, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.0682, \"times_seen\": 71.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"W\", \"escape\": -0.1149990440122225, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.1565, \"times_seen\": 26.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.36641105574958516, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.3609, \"times_seen\": 99.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"*\", \"escape\": -0.022405793056480137, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -2.2564, \"times_seen\": 7.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.012432745697620783, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.6319, \"times_seen\": 46.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.017315726193508386, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0101, \"times_seen\": 15.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.003862663465171332, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.1841, \"times_seen\": 3.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.03858188331571613, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.9247, \"times_seen\": 10.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.055070421343670996, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.9607, \"times_seen\": 12.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": 0.020496581025704157, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.2849, \"times_seen\": 20.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.027780670504279948, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0169, \"times_seen\": 114.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.02739317618765089, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.7514, \"times_seen\": 6.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.020398321244135934, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0194, \"times_seen\": 23.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": -0.006933057796697992, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1995, \"times_seen\": 10.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -1.7782447290613113, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.3342, \"times_seen\": 111.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.016989661249247365, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -1.7207, \"times_seen\": 14.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": 0.020165372798731, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.3897, \"times_seen\": 6.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.3544175900027941, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1864, \"times_seen\": 24.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.040324610123692387, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1394, \"times_seen\": 128.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.759185576154538, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1724, \"times_seen\": 27.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": -0.005799547569399888, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.169, \"times_seen\": 1.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": 0.0076505989799474355, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0853, \"times_seen\": 16.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.004290742886735296, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -3.1261, \"times_seen\": 1.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.0036968354803838944, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": 0.0743, \"times_seen\": 3.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.2656750771186297, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -0.2708, \"times_seen\": 24.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"M\", \"escape\": -0.009664930043401453, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": 0.0102, \"times_seen\": 5.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.005633163586458888, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -1.298, \"times_seen\": 3.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.002834657564632927, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -0.9615, \"times_seen\": 3.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.0187758666890883, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.0918, \"times_seen\": 7.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.016239774311232212, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.7998, \"times_seen\": 3.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.09209758013016588, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.2157, \"times_seen\": 42.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.015665481128757302, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": 0.1052, \"times_seen\": 9.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.004488072687810697, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.2887, \"times_seen\": 1.0}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.004774453626172077, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.9496, \"times_seen\": 1.0}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.003222193713732982, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.2311, \"times_seen\": 1.0}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.006061392755245297, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.8537, \"times_seen\": 3.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.05597012764666481, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -2.5867, \"times_seen\": 3.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.23589922303270458, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -0.1709, \"times_seen\": 15.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.0030764461084829726, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -1.3363, \"times_seen\": 1.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.019091849431189935, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -2.6411, \"times_seen\": 1.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"W\", \"escape\": -0.1476174035764936, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": 0.0603, \"times_seen\": 12.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.006920889422167514, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -1.9055, \"times_seen\": 6.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.0034783513245328253, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -2.6984, \"times_seen\": 1.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.007142825641390694, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -0.2144, \"times_seen\": 34.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.018723460796022964, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -0.8982, \"times_seen\": 7.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.00017055663036815607, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -2.5781, \"times_seen\": 1.0}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0008492149137017972, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -0.689, \"times_seen\": 1.0}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.06863809782397368, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -0.319, \"times_seen\": 43.0}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.031642409104140776, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -0.8253, \"times_seen\": 10.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.007644116394094964, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -2.9952, \"times_seen\": 2.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.01017318228965011, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -0.9598, \"times_seen\": 14.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.006951430147303347, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -2.5084, \"times_seen\": 13.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.06007461584594474, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -2.2382, \"times_seen\": 1.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.034028054953634576, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2093, \"times_seen\": 40.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"C\", \"escape\": -0.011305166277625588, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -2.4684, \"times_seen\": 6.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"D\", \"escape\": -0.00837203152668408, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -1.3467, \"times_seen\": 2.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"E\", \"escape\": -0.009785899873328605, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2733, \"times_seen\": 8.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"F\", \"escape\": 0.0436528798324389, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": 0.1178, \"times_seen\": 16.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": -0.06499651629374288, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.8031, \"times_seen\": 25.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.0647486460810881, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.4325, \"times_seen\": 23.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"I\", \"escape\": 0.685073305091829, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.1563, \"times_seen\": 11.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"K\", \"escape\": 0.011536696676745097, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -1.0839, \"times_seen\": 7.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.20673643212348025, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.3583, \"times_seen\": 88.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": -0.022272632068635223, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.248, \"times_seen\": 11.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"N\", \"escape\": 0.016080792201014986, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.6528, \"times_seen\": 14.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.6567725704939426, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2759, \"times_seen\": 36.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.15695026829186498, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.4712, \"times_seen\": 42.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.9287072245951536, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.3294, \"times_seen\": 58.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.036739694794765715, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.6163, \"times_seen\": 48.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": 0.04431982427418757, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2727, \"times_seen\": 19.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"W\", \"escape\": 0.011840117406070872, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.1322, \"times_seen\": 9.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"Y\", \"escape\": -0.019138397250762905, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.1029, \"times_seen\": 7.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"*\", \"escape\": -0.008506607612093021, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -2.9398, \"times_seen\": 1.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.01147551033305933, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -0.0781, \"times_seen\": 5.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.15034032630710892, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -0.506, \"times_seen\": 41.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.0029512595454152576, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -0.3039, \"times_seen\": 15.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.005482389530199709, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": 0.2744, \"times_seen\": 49.0}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.04220330040837195, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -2.2037, \"times_seen\": 2.0}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.004637059085698498, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -1.8361, \"times_seen\": 3.0}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.003782554283778119, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -2.1947, \"times_seen\": 1.0}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.02626702827656723, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -0.5299, \"times_seen\": 10.0}, {\"site\": 384, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.007820384997477985, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -0.9898, \"times_seen\": 4.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": 0.01138375444888062, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.4402, \"times_seen\": 5.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.018264231883390547, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.6615, \"times_seen\": 11.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.006751408690779551, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.2214, \"times_seen\": 2.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.11257018049298338, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.3296, \"times_seen\": 12.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.02781131864521138, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.0555, \"times_seen\": 13.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.4203224437572249, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -0.0239, \"times_seen\": 12.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.12353425896374469, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -0.6202, \"times_seen\": 31.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.001813553927536323, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.1265, \"times_seen\": 2.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.017899214031130272, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -0.9047, \"times_seen\": 16.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.054536823324914926, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.0617, \"times_seen\": 5.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.016801076012262037, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -0.5978, \"times_seen\": 4.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.022791519124209885, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.0642, \"times_seen\": 18.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.015338259975825035, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -2.8832, \"times_seen\": 4.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.012561166761841453, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -0.4952, \"times_seen\": 4.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.002040446935443837, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.5243, \"times_seen\": 1.0}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.019321822838711682, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -1.3162, \"times_seen\": 1.0}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"M\", \"escape\": -0.0030443061681040616, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -2.9312, \"times_seen\": 1.0}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.00308429937138212, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -3.0312, \"times_seen\": 1.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.004248358545174394, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.5699, \"times_seen\": 1.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.006870368197275747, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.2761, \"times_seen\": 10.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.060269463586903396, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -0.9432, \"times_seen\": 4.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0017720608703809043, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -0.1345, \"times_seen\": 1.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.008212226306944697, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -0.8816, \"times_seen\": 1.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.008852322959692965, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -2.7257, \"times_seen\": 5.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.005028260708990631, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -0.5996, \"times_seen\": 2.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.022324602069008253, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.5823946415495115, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.0117, \"times_seen\": 6.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.017882162863066865, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -2.4143, \"times_seen\": 1.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0013108273342630496, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -1.4106, \"times_seen\": 6.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.011333516967918466, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.9108, \"times_seen\": 3.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": 0.036108341134446366, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.2401, \"times_seen\": 2.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.009537805427202003, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.1483, \"times_seen\": 14.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.009347792503976491, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.0429, \"times_seen\": 7.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.018828953664161707, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -1.3135, \"times_seen\": 9.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.024860201922258733, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -1.6521, \"times_seen\": 4.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.02693328540278374, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -0.5212, \"times_seen\": 9.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.04251224980795122, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -0.7646, \"times_seen\": 22.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.013845594324247604, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": 0.0892, \"times_seen\": 6.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.0040602107592278705, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -1.234, \"times_seen\": 1.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.009551627842988413, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.0749, \"times_seen\": 6.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.0729744006540684, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.7207, \"times_seen\": 20.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.005246845493116912, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.1288, \"times_seen\": 1.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.018194364893329373, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -3.0099, \"times_seen\": 1.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.010571710969148952, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -0.6754, \"times_seen\": 4.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.0005807806713996547, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -1.9101, \"times_seen\": 1.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.02615886818664374, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -2.2252, \"times_seen\": 13.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.011768437824358737, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -0.6478, \"times_seen\": 26.0}, {\"site\": 395, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.002945236817967294, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -2.5021, \"times_seen\": 1.0}, {\"site\": 395, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.005335807128439513, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -2.7401, \"times_seen\": 1.0}, {\"site\": 396, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.006009015235311938, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -2.0107, \"times_seen\": 1.0}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"A\", \"escape\": -0.0060685265711104795, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.4528, \"times_seen\": 2.0}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.003938703646496891, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -3.222, \"times_seen\": 1.0}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.00020242642363761258, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.9552, \"times_seen\": 1.0}, {\"site\": 398, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.07180001864955225, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -1.2893, \"times_seen\": 18.0}, {\"site\": 398, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.009086475095032487, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -2.3023, \"times_seen\": 8.0}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.005837717519008427, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -1.6759, \"times_seen\": 2.0}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.009061277054791875, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -1.1369, \"times_seen\": 4.0}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.003155067151543831, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -2.3826, \"times_seen\": 1.0}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.02904979574103612, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -0.0074, \"times_seen\": 23.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.05278277755046946, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -1.8128, \"times_seen\": 5.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.009102086996689853, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -2.0965, \"times_seen\": 4.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.09749819622944521, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.2878, \"times_seen\": 59.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.06059048621990408, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.374, \"times_seen\": 23.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.02941875665770268, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.4068, \"times_seen\": 7.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.017496602241486255, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -1.9766, \"times_seen\": 1.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 1.082023700562837, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -0.7782, \"times_seen\": 3.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.02142266179361656, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -1.0488, \"times_seen\": 9.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.046992987005519446, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -1.5486, \"times_seen\": 18.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.040090577561586654, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.006129960793681705, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -2.6442, \"times_seen\": 1.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.013434853095313708, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": 0.1155, \"times_seen\": 32.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.013675575712386593, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.5414, \"times_seen\": 5.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.02329671424343091, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.2703, \"times_seen\": 27.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": 0.0014820782546528504, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.0143, \"times_seen\": 6.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.27927875181782946, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.4299, \"times_seen\": 42.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.0031204664054259295, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.444, \"times_seen\": 19.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.008799937371560826, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.8464, \"times_seen\": 12.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": 0.015502438901804014, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.2485, \"times_seen\": 8.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.0022789620088548663, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.7652, \"times_seen\": 32.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": 0.019225503372044227, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.4456, \"times_seen\": 15.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.03614760778320063, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.177, \"times_seen\": 24.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": -0.010301547113796074, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -2.2208, \"times_seen\": 5.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.02116708122517267, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.7947, \"times_seen\": 9.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.08917358183699933, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.4681, \"times_seen\": 26.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.07365121558631776, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": 0.0325, \"times_seen\": 32.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.024275286243610954, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.4711, \"times_seen\": 15.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.05393983943423191, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.6865, \"times_seen\": 18.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.0034300471789372312, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -2.549, \"times_seen\": 1.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.09486923547741237, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.8437, \"times_seen\": 34.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": -0.005107079816934192, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -2.8205, \"times_seen\": 2.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.004268069861274963, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.3349, \"times_seen\": 1.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.05881450060083892, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -1.2607, \"times_seen\": 26.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.00607334941524365, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -3.0059, \"times_seen\": 4.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.7005810449878432, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -0.2443, \"times_seen\": 35.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.011831030319126166, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -1.9623, \"times_seen\": 2.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.08473501936131424, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -0.1177, \"times_seen\": 44.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.691032696320357, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": 0.0434, \"times_seen\": 34.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.00418083724301634, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -1.3395, \"times_seen\": 10.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.0026780236654221374, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"A\", \"escape\": -0.02437681281368207, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.3577, \"times_seen\": 23.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.014245190189835857, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -2.5459, \"times_seen\": 4.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"D\", \"escape\": -0.02123586128702211, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.8467, \"times_seen\": 7.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.020775777207771635, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.7397, \"times_seen\": 24.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"F\", \"escape\": -0.04489870354391089, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.5255, \"times_seen\": 20.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.8992931197089454, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4055, \"times_seen\": 38.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": 0.023871336323018594, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2608, \"times_seen\": 19.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.026878648105632934, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.5483, \"times_seen\": 89.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -1.0681464900654818, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4969, \"times_seen\": 63.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.8579772437952248, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.9469, \"times_seen\": 36.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.007025066196245449, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.6264, \"times_seen\": 11.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": -0.053520213711055434, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4278, \"times_seen\": 16.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"P\", \"escape\": -0.024022773317016657, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4112, \"times_seen\": 40.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": -0.024901278914601345, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2147, \"times_seen\": 18.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.05292560466178072, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2414, \"times_seen\": 94.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.023437682012727088, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.3503, \"times_seen\": 68.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"V\", \"escape\": 0.0008146474730066518, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4723, \"times_seen\": 22.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.043246678857387075, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2314, \"times_seen\": 8.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"Y\", \"escape\": -0.011052343038732922, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.0626, \"times_seen\": 15.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"*\", \"escape\": 0.0177427766543785, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -2.695, \"times_seen\": 4.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.0018519370118391977, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -1.3489, \"times_seen\": 9.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.007621886249344873, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9692, \"times_seen\": 2.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.008323858012438894, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9548, \"times_seen\": 6.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.002957635979585219, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.8838, \"times_seen\": 3.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 1.5998332297176685, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9451, \"times_seen\": 10.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": 0.027886697396762375, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9533, \"times_seen\": 1.0}, {\"site\": 407, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.0016561216693887135, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -2.8913, \"times_seen\": 1.0}, {\"site\": 407, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.022518784047420158, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -0.341, \"times_seen\": 39.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.004106119291182267, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.4914, \"times_seen\": 2.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.0073283227109608405, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -1.9209, \"times_seen\": 2.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.025851471797686997, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -1.204, \"times_seen\": 27.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.012182697386177782, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 4.461854707974564e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.5928, \"times_seen\": 18.0}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.002390273046764505, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.5839, \"times_seen\": 1.0}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.0016830249982182903, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.9764, \"times_seen\": 1.0}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.014368232483223574, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.8876, \"times_seen\": 2.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.009675579177838612, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -0.7148, \"times_seen\": 6.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0048476128235536336, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -1.6159, \"times_seen\": 4.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.03265560806463823, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -0.2529, \"times_seen\": 12.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -1.2331954846343032, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.0003, \"times_seen\": 10.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.018171193508962024, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.7582, \"times_seen\": 4.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.009545553851354202, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.2885, \"times_seen\": 1.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 1.5257356452306978, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.3983, \"times_seen\": 1.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.00962492382294895, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -1.8486, \"times_seen\": 12.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.07014063948070615, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.7464, \"times_seen\": 16.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.009795011972352977, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -2.1803, \"times_seen\": 7.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.004797422420493662, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.6686, \"times_seen\": 8.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.10176259168990012, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.1443, \"times_seen\": 11.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.03196740798076725, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.4647, \"times_seen\": 16.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.08144677525253036, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.1293, \"times_seen\": 4.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.008254202282797189, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -2.1157, \"times_seen\": 2.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.13706996719761227, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.3731, \"times_seen\": 48.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.028000707427770593, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.043, \"times_seen\": 1.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.7598652844200418, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.2426, \"times_seen\": 18.0}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.00353400561599803, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.4364, \"times_seen\": 5.0}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 0.013405935804936271, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.0016364050496400356, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -3.1206, \"times_seen\": 1.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": -0.09804397060551602, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.0135, \"times_seen\": 28.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"C\", \"escape\": -0.029173066349918293, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.9425, \"times_seen\": 12.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.005227919782289377, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -1.1213, \"times_seen\": 10.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"E\", \"escape\": -0.004151374508990893, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.8444, \"times_seen\": 13.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": -0.014277018351996816, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.2752, \"times_seen\": 11.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.5883364603725308, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.7688, \"times_seen\": 29.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.4990387326273408, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0806, \"times_seen\": 24.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.022428184242365177, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.171, \"times_seen\": 21.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.44149846695816874, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.1677, \"times_seen\": 39.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": -0.031014867232553284, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0495, \"times_seen\": 45.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": 0.04743035576072658, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0532, \"times_seen\": 15.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"P\", \"escape\": -0.12141951181519355, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.1462, \"times_seen\": 42.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.011582398142381876, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.0824, \"times_seen\": 4.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": 0.06656425325984246, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.1734, \"times_seen\": 54.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.3462198099396206, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.2119, \"times_seen\": 40.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.027098137331394063, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0517, \"times_seen\": 62.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": -0.04670309469558651, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.2189, \"times_seen\": 23.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"W\", \"escape\": -0.004827222481856886, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.3319, \"times_seen\": 5.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.21107242476549354, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.1926, \"times_seen\": 19.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"*\", \"escape\": -0.025169614749301274, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -2.6092, \"times_seen\": 5.0}, {\"site\": 415, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.0014952932291306506, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -1.2658, \"times_seen\": 1.0}, {\"site\": 415, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.05570161129012191, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -0.8129, \"times_seen\": 14.0}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.003516004596075262, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -2.7621, \"times_seen\": 1.0}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.009296250444635437, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -2.4187, \"times_seen\": 4.0}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.0034184076837431685, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -2.8538, \"times_seen\": 4.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.013672263668652396, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -1.2512, \"times_seen\": 4.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.0062876656419970185, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -2.7506, \"times_seen\": 5.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.009451472286011727, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -2.9881, \"times_seen\": 1.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.4034909426009903, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -0.0155, \"times_seen\": 29.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": 0.010231195337294684, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -2.0778, \"times_seen\": 5.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.619682598744699, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -1.6177, \"times_seen\": 12.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"A\", \"escape\": 0.02326778772467451, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.0424, \"times_seen\": 4.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.007931075288614316, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -0.3202, \"times_seen\": 14.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.011732422739431354, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -0.9485, \"times_seen\": 10.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.013881360491128805, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.8359, \"times_seen\": 6.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.004841973598378504, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.9341, \"times_seen\": 1.0}, {\"site\": 419, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.0012276770660955018, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -0.3505, \"times_seen\": 1.0}, {\"site\": 420, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.057256842680597345, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -0.1813, \"times_seen\": 1.0}, {\"site\": 420, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.293286317610129, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -2.2681, \"times_seen\": 1.0}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.03925201942958013, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.007379385927605127, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -2.5108, \"times_seen\": 2.0}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.009638428585773557, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -0.928, \"times_seen\": 10.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.01366626374193656, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.2721, \"times_seen\": 7.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.003828105681459775, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.7344, \"times_seen\": 2.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.0013421847689156672, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -1.9279, \"times_seen\": 1.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.004116418277349058, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.5957, \"times_seen\": 1.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0163112933791978, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.6278, \"times_seen\": 7.0}, {\"site\": 423, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.005800056513542365, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -1.765, \"times_seen\": 13.0}, {\"site\": 423, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.006324050616206821, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -2.888, \"times_seen\": 3.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.01750768896427318, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.6326, \"times_seen\": 7.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.04313934285039547, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.1615, \"times_seen\": 9.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -2.5282959800764133, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.5222, \"times_seen\": 16.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.011993604428563115, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.4526, \"times_seen\": 12.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.3601399448754066, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.2103, \"times_seen\": 48.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.03623015293058868, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -1.0111, \"times_seen\": 4.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.009074788215875502, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.4356, \"times_seen\": 2.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.1326628120974909, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.3463, \"times_seen\": 27.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.003903279231868352, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.3824, \"times_seen\": 5.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.012782145866393995, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.1124, \"times_seen\": 9.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.013813866245332918, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.96, \"times_seen\": 9.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.014502095922096517, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.1979, \"times_seen\": 4.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.010894089409781163, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.2893, \"times_seen\": 4.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.0012539731933507432, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.8063, \"times_seen\": 18.0}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.009720914237349122, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.3704, \"times_seen\": 3.0}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.0015736427059116801, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.3682, \"times_seen\": 1.0}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0036968252037183776, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.1454, \"times_seen\": 1.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.015426687275162245, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -1.1343, \"times_seen\": 6.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.05139877458423222, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -0.092, \"times_seen\": 30.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.013201829792948492, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -1.7059, \"times_seen\": 1.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.0008227006016522863, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -0.7532, \"times_seen\": 5.0}, {\"site\": 428, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.014843677181506214, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -1.2965, \"times_seen\": 7.0}, {\"site\": 428, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.0037863799696999097, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -2.9554, \"times_seen\": 1.0}, {\"site\": 429, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": 0.0057025452530259915, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -2.7205, \"times_seen\": 3.0}, {\"site\": 430, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.007694978360808763, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -1.3058, \"times_seen\": 4.0}, {\"site\": 430, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.0004994053881240524, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -2.811, \"times_seen\": 2.0}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.015550801780708414, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.0207, \"times_seen\": 1.0}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0016006636538674758, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -1.4261, \"times_seen\": 2.0}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.012476627824670905, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.5007, \"times_seen\": 7.0}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.9824514135203959, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.4859, \"times_seen\": 15.0}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.0536746986435413, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -0.0533, \"times_seen\": 24.0}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.049784223876675956, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -0.5215, \"times_seen\": 19.0}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.013397133689247982, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -1.2557, \"times_seen\": 9.0}, {\"site\": 433, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.024678902249198376, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -2.0667, \"times_seen\": 22.0}, {\"site\": 433, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": -0.015350002380590495, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -2.5145, \"times_seen\": 10.0}, {\"site\": 434, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.003605423094993517, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.049654989423796196, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.3883, \"times_seen\": 5.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 1.9593342122028008, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.1849, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.013130374483286905, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.9279, \"times_seen\": 2.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.02367571737523028, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.7564, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 2.9902588777693517, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.0882, \"times_seen\": 8.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.05101136631475868, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.1017, \"times_seen\": 6.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 1.5385704621224816, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.4674, \"times_seen\": 1.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": 0.016876975686188816, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.027074082227422067, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": 3.839339491084656, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.0061703486041247, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.03499239047798595, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.007452001126785125, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 2.6638838987662563, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": 0.04943721062257711, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.001175724486255462, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": 0.019514357374329702, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": 0.02288760395355997, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 3.842039706589607, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 4.280575467950762, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": 0.005026561001255139, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"W\", \"escape\": 0.01704523720368397, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 4.840163734877134, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": -0.016187379040567468, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.028, \"times_seen\": 21.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": 0.0020952787629950724, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.979, \"times_seen\": 1.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": 2.0714394191790726, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1224, \"times_seen\": 14.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.02458861343075173, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.3113, \"times_seen\": 15.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": 2.077082419506872, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.206, \"times_seen\": 5.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.025010990291817654, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0017, \"times_seen\": 24.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": 0.44523630283579185, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.221, \"times_seen\": 12.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.011955039118754979, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8004, \"times_seen\": 13.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": 0.06674394656277079, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8499, \"times_seen\": 18.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.021504323662662934, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.0401, \"times_seen\": 10.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.04449714367212812, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2118, \"times_seen\": 36.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 0.03700577442486714, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.534, \"times_seen\": 8.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.009798291681692326, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1906, \"times_seen\": 16.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.07259669208489553, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.1206, \"times_seen\": 36.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": 0.03806882712281091, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2856, \"times_seen\": 44.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.041700776104086686, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0087, \"times_seen\": 29.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": 1.5346382462439476, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.4789, \"times_seen\": 13.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": 0.006918148207380637, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.2464, \"times_seen\": 5.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": 0.026959119161880228, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.2806, \"times_seen\": 16.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": -0.42527813861704267, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.7496, \"times_seen\": 5.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.025887618917153174, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.1303, \"times_seen\": 10.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0010546119797628876, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0594, \"times_seen\": 19.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.006023654749645401, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0273, \"times_seen\": 3.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.027509800937071022, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -2.2021, \"times_seen\": 6.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.006392539814038205, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.4385, \"times_seen\": 1.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.009859570194722896, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.74, \"times_seen\": 7.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.002384512751299189, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.3662, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.036966492849980485, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.6793, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.007388632704244411, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -2.4152, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.017239849869309973, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -0.8693, \"times_seen\": 2.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.0014282848810145583, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.02547035101203864, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 1.4854199203475613, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.029425100714127992, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 4.063809424472797, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.029795880103947594, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 5.630994173127478, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 5.1086146407806865, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": 3.601176521263643, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 5.451072788423554, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 5.158100915373215, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 3.324246403354797, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 6.1290783809820235, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 5.900694848610817, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 3.9775012177139013, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 5.776702441877219, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 5.433520471039357, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.0658696734379375, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.10764957793359685, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 1.8146941311447389, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.1490667878234352, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.003238257752983392, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -1.1124061834450978, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": 3.1453407050769484, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 2.8824331547297675, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.7528519266774695, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 1.4011436692746244, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 4.456211089334324, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 3.0336926843872583, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 3.387480139162705, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": 2.3726710708286567, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.9092344797024997, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 5.910853781570541, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.02145856929009738, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 3.1491138529867637, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 4.339011094817089, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 3.998257448689287, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 2.986754504842179, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 3.7230595085829528, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": 0.017813206405905304, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 6.626967084842634, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 6.9968035172164935, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 5.398771190014916, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 6.679871463038464, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 3.301384133577125, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 4.938491124508558, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 3.560227323591795, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 3.2913887871561567, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 3.9365807945092595, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.03030822275433241, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.4238, \"times_seen\": 2.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.006960082098913793, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2586, \"times_seen\": 9.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.016983788073247807, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.1014, \"times_seen\": 12.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.09860217240331291, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2543, \"times_seen\": 80.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.044695774588294976, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.3976, \"times_seen\": 23.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": 0.42454925660687665, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.4215, \"times_seen\": 9.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"V\", \"escape\": 3.3339843635593125, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.095, \"times_seen\": 5.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.00875184387455288, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -2.6941, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 1.2022660589898748, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": 0.084433226970637, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.024790285647301902, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -1.2399737883008233, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 6.327675433070906, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 5.706819510130076, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.04901797470105145, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 1.6502057672122266, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.0316, \"times_seen\": 30.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.06470225882441528, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.5391, \"times_seen\": 5.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"-\", \"escape\": 0.05528621899928093, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": 0.042205617460028336, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": 0.9978127612427541, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": -0.03170746988406976, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": -0.01847093949272139, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.9028575191921331, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": -0.07230632197069453, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.03616152328648847, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.07866464108235376, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.01579370170150462, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.09091326855928183, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": -0.03791333106622611, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.10094672960033615, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.9146915645192252, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.1578990223083731, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.6848171270303757, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": 2.3858578355583213, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.02000079016450145, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.7186709202437289, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": 0.019576487350403526, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.1313, \"times_seen\": 22.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"*\", \"escape\": -0.0011904090429413622, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": 0.016473952366292576, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.0023484564474220496, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -1.9525, \"times_seen\": 1.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.16694021426571107, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.4406, \"times_seen\": 13.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.04337477246832893, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.9062, \"times_seen\": 9.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"R\", \"escape\": -0.007128442259501085, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.6085, \"times_seen\": 3.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.00348527491046708, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -2.3815, \"times_seen\": 1.0}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.005951462841764855, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0722, \"times_seen\": 2.0}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.005448050843341368, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0305, \"times_seen\": 3.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.00926826650327956, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -0.0855, \"times_seen\": 21.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.008579064463563994, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.2134, \"times_seen\": 3.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.060285876009812445, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.1937, \"times_seen\": 17.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.011449735607783583, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.2447, \"times_seen\": 4.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.008032535609579002, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -0.0584, \"times_seen\": 5.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.00910665693834918, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -0.306, \"times_seen\": 1.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.03518304319186407, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -0.6037, \"times_seen\": 11.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.42150662053267834, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -0.8152, \"times_seen\": 5.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.012348891672379436, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": 0.2206, \"times_seen\": 2.0}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.039827081661018025, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -2.4922, \"times_seen\": 4.0}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.0018891325866977043, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -3.0332, \"times_seen\": 1.0}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.013733193977373302, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -3.0393, \"times_seen\": 3.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.02420888868166121, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.1772, \"times_seen\": 10.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.00014627373985151177, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.5111, \"times_seen\": 2.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.001001139464320643, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.2319, \"times_seen\": 1.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.009305938655668899, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.0638, \"times_seen\": 17.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.15842876790015012, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.1467, \"times_seen\": 10.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.4299831236200609, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.064, \"times_seen\": 20.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.007395232057417415, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.3853, \"times_seen\": 5.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.001802816575458431, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.017916775961208522, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.7345, \"times_seen\": 15.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.016404928930982186, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2959, \"times_seen\": 7.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.0013611603963141002, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.5048, \"times_seen\": 2.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.04636028857121049, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.3614, \"times_seen\": 5.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.021282041423993262, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2345, \"times_seen\": 13.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.007030883711179924, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.5813, \"times_seen\": 2.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.0032167590795865683, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.1484, \"times_seen\": 3.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -1.0222169101430467, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2011, \"times_seen\": 4.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.009751759284423612, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -1.2551, \"times_seen\": 4.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.022980462590434847, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.0782, \"times_seen\": 2.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.032518819453357176, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.1905, \"times_seen\": 3.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -1.9183496528380468, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.0494, \"times_seen\": 15.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.042737710385083096, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.3183, \"times_seen\": 8.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.004702417199280909, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.997, \"times_seen\": 3.0}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.012266819535741536, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": 0.4167, \"times_seen\": 1.0}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0024391681418169213, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -1.7193, \"times_seen\": 1.0}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.016616890646595158, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -3.0553, \"times_seen\": 3.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.04953712124882878, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -0.9144, \"times_seen\": 8.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.01442402781056407, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -2.0544, \"times_seen\": 2.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.0110709109063406, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -0.027, \"times_seen\": 3.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.052980639163758635, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": 0.245, \"times_seen\": 4.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"F\", \"escape\": -0.003233037388854348, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -3.0357, \"times_seen\": 1.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.016811721045036452, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -3.1966, \"times_seen\": 1.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.001772562916636744, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -1.6084, \"times_seen\": 1.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.005634090919660326, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -1.9766, \"times_seen\": 8.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0076164395181931325, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -2.697, \"times_seen\": 2.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.018998753315629398, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -1.2792, \"times_seen\": 12.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.014538331298202185, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -0.6701, \"times_seen\": 1.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.002651888969703013, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -2.6458, \"times_seen\": 1.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.018778658600038425, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -0.29, \"times_seen\": 1.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.011079618068365743, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -1.5638, \"times_seen\": 3.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.003649906522184591, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -1.4526, \"times_seen\": 16.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.013778279508619522, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -1.101, \"times_seen\": 9.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.01246556789669117, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -2.4745, \"times_seen\": 2.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.001461443827653946, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -2.4968, \"times_seen\": 1.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.0019066933661283944, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -2.7086, \"times_seen\": 2.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.003823199199059278, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -2.6585, \"times_seen\": 1.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.008520797370730122, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -0.9854, \"times_seen\": 6.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.03482230382181508, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -1.8776, \"times_seen\": 8.0}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 1.586318669782464e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.7075, \"times_seen\": 1.0}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.017916660058855567, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.9013, \"times_seen\": 1.0}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.0037178602615859143, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.6267, \"times_seen\": 1.0}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.0028933197562489633, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.016036640529762277, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -2.1352, \"times_seen\": 2.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.10156144251162233, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.349, \"times_seen\": 5.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.016071128754364332, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.6158, \"times_seen\": 1.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.01854639071197271, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.4385, \"times_seen\": 23.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.006413121332176052, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.6714, \"times_seen\": 9.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0033114247248614585, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -1.8312, \"times_seen\": 6.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.08495316332728974, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -0.6392, \"times_seen\": 12.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.05531958956101881, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -0.7065, \"times_seen\": 31.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.005100697088382124, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -2.4014, \"times_seen\": 1.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.00938257187243344, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.3892, \"times_seen\": 6.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.08927761790913842, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.5468, \"times_seen\": 43.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.8569155584093111, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.5988, \"times_seen\": 5.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.013636566681611867, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": 0.0284, \"times_seen\": 33.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.007889317409795983, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": 0.3772, \"times_seen\": 7.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.0033173281427046294, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.8349, \"times_seen\": 6.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.004847050517771606, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.5909, \"times_seen\": 6.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.004713960818426205, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.101, \"times_seen\": 12.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.09547222284245303, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.7486, \"times_seen\": 23.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.022940201805113955, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -1.4314, \"times_seen\": 13.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.06700445317716644, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.2862, \"times_seen\": 41.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.015138326026016936, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.6964, \"times_seen\": 6.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.0034200433411709858, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -2.4359, \"times_seen\": 1.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.05220269370328934, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -0.9636, \"times_seen\": 4.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.009346417243571393, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": 0.1237, \"times_seen\": 5.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.0015332407857832518, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": 0.0321, \"times_seen\": 1.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.004770153914285873, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.025960092382716633, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -1.1749, \"times_seen\": 18.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.0019634634097719463, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -0.4416, \"times_seen\": 9.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.03935615365625864, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -2.3124, \"times_seen\": 1.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.033013128826314, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": 0.0095, \"times_seen\": 16.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.019510554464892287, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -0.6, \"times_seen\": 7.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.0028038344956439897, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -1.6109, \"times_seen\": 1.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.006301472064272689, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -2.7598, \"times_seen\": 2.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.42658807043353664, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -0.3826, \"times_seen\": 6.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.3716422028203824, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -1.3723, \"times_seen\": 11.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.004033653110238076, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -1.1986, \"times_seen\": 7.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.002031256180800594, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -1.3102, \"times_seen\": 29.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.002227985367078973, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -2.3923, \"times_seen\": 1.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.014740202963826433, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -1.0243, \"times_seen\": 9.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.009693587551387231, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.6215, \"times_seen\": 4.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.15823580768574344, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.4959, \"times_seen\": 19.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.0489102110398461, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.6461, \"times_seen\": 23.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.09765773635161062, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.1795, \"times_seen\": 17.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.021535840434201793, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -0.5457, \"times_seen\": 7.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.0034419554577783014, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -2.2789, \"times_seen\": 1.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.050657111289922375, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -0.7248, \"times_seen\": 44.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.005435084111456338, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -2.7481, \"times_seen\": 2.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.037744146485015194, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": -0.01624316964185816, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5291, \"times_seen\": 7.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"C\", \"escape\": -0.006041178641337985, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -2.4417, \"times_seen\": 2.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.029476810358014385, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.3592, \"times_seen\": 13.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": -0.010399581923758512, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.6824, \"times_seen\": 3.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.04964477386727058, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.3226, \"times_seen\": 16.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.01966672672591382, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.1796, \"times_seen\": 7.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.03383667548182063, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.2299, \"times_seen\": 23.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.0373406789583331, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0419, \"times_seen\": 17.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": -0.0013964552181635187, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5132, \"times_seen\": 12.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.0052057117453157865, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5954, \"times_seen\": 5.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"P\", \"escape\": 0.0021296541585549738, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.1628, \"times_seen\": 19.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.028865256406804145, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0043, \"times_seen\": 7.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": -0.017027545338678583, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5627, \"times_seen\": 18.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.42042545825715566, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0281, \"times_seen\": 46.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.06935833126016615, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0542, \"times_seen\": 47.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": -0.02891036555918323, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.0493, \"times_seen\": 9.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"W\", \"escape\": -0.0038958304295510665, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -1.0221, \"times_seen\": 1.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.04769408324242543, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.9565, \"times_seen\": 11.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"*\", \"escape\": -0.017762482400122546, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -2.7271, \"times_seen\": 1.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.004174328217353265, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": 0.007245506450777908, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1629, \"times_seen\": 17.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": -0.004333796803288223, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -2.4135, \"times_seen\": 1.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": 0.002544239434819903, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1663, \"times_seen\": 4.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -1.5884041860475293, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.1619, \"times_seen\": 23.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": -0.010794787703310734, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.3474, \"times_seen\": 6.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.03710408729874231, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.5754, \"times_seen\": 15.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.027375665211448873, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.104, \"times_seen\": 12.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.39091190734354175, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.2191, \"times_seen\": 25.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.009226182339953154, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1538, \"times_seen\": 18.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.021799059928906368, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.2939, \"times_seen\": 20.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.011957382292925178, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.2213, \"times_seen\": 26.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 0.037387545523802385, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -2.0058, \"times_seen\": 6.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.009629206084930949, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.1862, \"times_seen\": 12.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.1952201753539803, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1985, \"times_seen\": 66.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.05408361701078577, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.0548, \"times_seen\": 28.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.11821598569099455, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.1097, \"times_seen\": 40.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.04080059873156311, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.084, \"times_seen\": 22.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": -0.010617269125522058, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -1.0061, \"times_seen\": 11.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": 0.07932411813283234, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1538, \"times_seen\": 11.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": -0.01724776352651861, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -3.0352, \"times_seen\": 4.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": -0.004232987373915251, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.0037851977766165555, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.5907, \"times_seen\": 6.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.014022780466669396, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.8606, \"times_seen\": 19.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -1.9734246117362138, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.9326, \"times_seen\": 15.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.03671151820802939, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.2531, \"times_seen\": 10.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.00867133801228982, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.6761, \"times_seen\": 1.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -1.1418667647237732, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": 0.0541, \"times_seen\": 19.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0006377672220946651, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.0611, \"times_seen\": 14.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"-\", \"escape\": -0.013287877831392821, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 477, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": 0.01775753754345586, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.6892, \"times_seen\": 1.0}, {\"site\": 477, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": -0.0025705975289248492, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.029157169961418337, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.1436, \"times_seen\": 25.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.014276632141736408, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.2157, \"times_seen\": 10.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.012548575185961504, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -2.158, \"times_seen\": 3.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.004313270252817572, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.2804, \"times_seen\": 70.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.4186314724688783, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.4046, \"times_seen\": 38.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.02436480697528212, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.2739, \"times_seen\": 10.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.3176693759324339, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.4916, \"times_seen\": 36.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.04084022943511154, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.67, \"times_seen\": 10.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.010214412399420092, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.9962, \"times_seen\": 8.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.00712553902560352, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.7021, \"times_seen\": 30.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.05895813295698689, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -1.8789, \"times_seen\": 17.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.051739238779149765, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.1605, \"times_seen\": 4.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.015353168599166116, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.1194, \"times_seen\": 2.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.015886915893926424, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.843, \"times_seen\": 17.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.01383477993504073, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.3308, \"times_seen\": 7.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.015186319481689919, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": 0.0897, \"times_seen\": 17.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.11261221208834278, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.1138, \"times_seen\": 31.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.0013056393503403524, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": 0.042, \"times_seen\": 8.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.01590679312451643, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -2.9819, \"times_seen\": 4.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.12685531445784057, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -1.4618, \"times_seen\": 36.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.12727039988664612, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.2489, \"times_seen\": 20.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.043037686467729055, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.8377, \"times_seen\": 14.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.1685808728208006, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.696, \"times_seen\": 50.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.06767858874810459, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.6341, \"times_seen\": 14.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.030361310983312247, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.1683, \"times_seen\": 10.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.0449298920473189, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.3417, \"times_seen\": 18.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.06771797345047785, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.1515, \"times_seen\": 32.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.004318816486377853, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.3964, \"times_seen\": 5.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.06099060924399841, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.7223, \"times_seen\": 19.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.011863364260667, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": 0.0548, \"times_seen\": 56.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.03851464193544204, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.136, \"times_seen\": 18.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 0.07857256215341171, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.2489, \"times_seen\": 33.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.1916766322596123, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.2204, \"times_seen\": 55.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.05932804473184401, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": 0.0389, \"times_seen\": 84.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.007476710198434448, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.0617, \"times_seen\": 67.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": -0.012251792576456996, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -2.5984, \"times_seen\": 4.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": 0.010972268758786596, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -1.1779, \"times_seen\": 13.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.003751335038349959, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -2.7147, \"times_seen\": 1.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.05749923307389745, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.7599, \"times_seen\": 32.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.00277880328791045, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -1.7725, \"times_seen\": 1.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.34700166500430546, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.4621, \"times_seen\": 34.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.024325211475512528, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -1.2887, \"times_seen\": 11.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.13451969362677826, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.1985, \"times_seen\": 40.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.0032165914961376028, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.7847, \"times_seen\": 1.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.050440761363946915, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -1.5063, \"times_seen\": 11.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.07371306294945103, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.0929, \"times_seen\": 15.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -1.0628082167798938, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.1442, \"times_seen\": 15.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.20152739241403955, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.1937, \"times_seen\": 40.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.04030493806629376, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": -0.0454, \"times_seen\": 9.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.0031226622981972343, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": 0.3125, \"times_seen\": 1.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.009410500758877737, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -2.8443, \"times_seen\": 3.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.01908001420015764, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -0.32, \"times_seen\": 7.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.010660642597083709, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -0.3665, \"times_seen\": 3.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -1.6832061086077588, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -3.08, \"times_seen\": 1.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.02333570914061109, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.961, \"times_seen\": 3.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": -0.01753227722748161, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.8571, \"times_seen\": 1.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.02926730478726124, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.3412, \"times_seen\": 4.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": -0.02448579574513657, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.9821, \"times_seen\": 2.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.04879169654509038, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -1.0498, \"times_seen\": 1.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.010553243537483109, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -1.714, \"times_seen\": 1.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -1.224247077129129, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -0.2363, \"times_seen\": 37.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.010149133637186178, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -0.4084, \"times_seen\": 2.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"W\", \"escape\": -0.04001389933416903, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -0.3635, \"times_seen\": 4.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.010431056545356737, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -2.3672, \"times_seen\": 1.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.009612941992007414, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.5613, \"times_seen\": 3.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.02958203681584409, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.6844, \"times_seen\": 10.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"R\", \"escape\": -0.005520839687385023, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -2.5252, \"times_seen\": 2.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.005657717721070703, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.2581, \"times_seen\": 6.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.010339626002295465, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.0441, \"times_seen\": 2.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.0010078138423837938, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": 0.0991, \"times_seen\": 11.0}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.015295198077255929, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -1.8109, \"times_seen\": 3.0}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.003785432824216986, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -3.0999, \"times_seen\": 1.0}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0030496459237147086, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -2.9169, \"times_seen\": 1.0}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.017380213697344306, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -2.4022, \"times_seen\": 4.0}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.0005943377620873678, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -1.0383, \"times_seen\": 1.0}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.010442226404871276, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -1.8611, \"times_seen\": 2.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"A\", \"escape\": 0.09717965317461574, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.3866, \"times_seen\": 45.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.020454146082127953, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.3533, \"times_seen\": 3.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"D\", \"escape\": 0.012003597672498447, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.5278, \"times_seen\": 7.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": 0.14522557420032764, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.2944, \"times_seen\": 16.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"F\", \"escape\": -0.020721025017947047, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.0279, \"times_seen\": 2.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.052526207722921776, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.9766, \"times_seen\": 42.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": -0.11027758294669453, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.7874, \"times_seen\": 46.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": 0.01620014441678945, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.119, \"times_seen\": 7.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.034890865947461214, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.0552, \"times_seen\": 34.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.010641140377459281, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.6339, \"times_seen\": 30.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.02948608805080504, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.8017, \"times_seen\": 6.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.007830717905123633, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.746, \"times_seen\": 5.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"P\", \"escape\": -0.00992064402298476, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.6584, \"times_seen\": 5.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": 0.10543116571547466, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.2715, \"times_seen\": 26.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.013605057530706654, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.6663, \"times_seen\": 45.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.004573057431371525, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.8249, \"times_seen\": 22.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"V\", \"escape\": 0.7234994196561533, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.7732, \"times_seen\": 34.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.04643466861937198, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.7173, \"times_seen\": 2.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"Y\", \"escape\": -0.05163485710089124, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.2071, \"times_seen\": 13.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"*\", \"escape\": -0.004492454632258282, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.5897, \"times_seen\": 2.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.03036893976742736, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.1818, \"times_seen\": 3.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.0204828189487954, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -1.5274, \"times_seen\": 2.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 3.0541620127095013, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -1.0881, \"times_seen\": 11.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.028946087361943488, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.5503, \"times_seen\": 23.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.0040425613496468645, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.1058, \"times_seen\": 11.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 1.4862891670535328, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.9805, \"times_seen\": 5.0}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.006376449251746134, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.3786, \"times_seen\": 8.0}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"W\", \"escape\": -0.002016217323796886, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.1345, \"times_seen\": 1.0}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"-\", \"escape\": -0.0045478592317831044, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.1158279352556814, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0471, \"times_seen\": 44.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.032879163982406805, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -1.1981, \"times_seen\": 31.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -0.09289686377286883, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.2573, \"times_seen\": 29.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": 0.09245682456113563, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.4075, \"times_seen\": 3.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.0871365091760881, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.6332, \"times_seen\": 19.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.416753540574911, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0404, \"times_seen\": 50.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.06450654355611667, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.0759, \"times_seen\": 23.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.016371889219621554, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.1474, \"times_seen\": 33.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 2.3329262444725245, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.6137, \"times_seen\": 7.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.354182081412522, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.5501, \"times_seen\": 34.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.6440618340061263, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.1907, \"times_seen\": 7.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 1.4200396202312007, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.1379, \"times_seen\": 47.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.005776222054965023, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -2.2628, \"times_seen\": 13.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.01087868176190713, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0007, \"times_seen\": 5.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 1.7334108908368124, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -1.4775, \"times_seen\": 39.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.955903659354399, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0331, \"times_seen\": 36.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.2117759224305595, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.1352, \"times_seen\": 46.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.02181826897409412, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -1.3651, \"times_seen\": 7.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 1.4279085155219675, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.4377, \"times_seen\": 12.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.0018785983017730733, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"H\", \"escape\": -0.0027851398827067365, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -2.6818, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.0919820134098971, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -2.4924, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.0060590643279986615, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -2.9094, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"W\", \"escape\": 0.023365379437680765, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -0.8619, \"times_seen\": 6.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": -0.005991163863425432, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"A\", \"escape\": -0.011957739160905255, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.043, \"times_seen\": 5.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.004163409803657323, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -2.4122, \"times_seen\": 1.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"D\", \"escape\": 0.017279568008649732, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.7782, \"times_seen\": 2.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": 0.015627764046850543, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.2172, \"times_seen\": 9.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"F\", \"escape\": 0.0024044810362835057, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.0421, \"times_seen\": 11.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.09132169780663098, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.3789, \"times_seen\": 28.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": -0.028863867276678275, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.2841, \"times_seen\": 10.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.028841103701055987, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.1404, \"times_seen\": 9.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.032155731432797846, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.1592, \"times_seen\": 24.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.006612009634621932, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.3126, \"times_seen\": 16.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.06681048149380545, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.1347, \"times_seen\": 15.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.005535455855025695, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.0844, \"times_seen\": 5.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"P\", \"escape\": -0.001414371918178172, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -2.7657, \"times_seen\": 1.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": 0.016925470216810623, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.0442, \"times_seen\": 8.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.06431894000275516, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.0007, \"times_seen\": 13.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.034732886347059184, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.1952, \"times_seen\": 12.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"V\", \"escape\": -0.031215859868844054, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.2869, \"times_seen\": 12.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": 5.012749870381591, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.8692, \"times_seen\": 9.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"Y\", \"escape\": -0.011531641320644935, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.0976, \"times_seen\": 7.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"*\", \"escape\": 0.02427208422196662, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -2.4975, \"times_seen\": 2.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": -0.00232457087545251, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 4.562162837297962, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.4608, \"times_seen\": 4.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.18074071045088358, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -1.8239, \"times_seen\": 3.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 4.466047378479611, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.5042, \"times_seen\": 2.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 2.4730388174292304, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -2.0994, \"times_seen\": 6.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 6.192513290847611, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.0307, \"times_seen\": 10.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 6.011168990466134, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.3631, \"times_seen\": 3.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": 5.294696691239055, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -2.3457, \"times_seen\": 2.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"-\", \"escape\": 0.15659798985835924, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 3.890330159234849, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": -0.5078, \"times_seen\": 13.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.031200556126103552, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": -1.0395, \"times_seen\": 5.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 1.332651324465535, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": 0.2023, \"times_seen\": 4.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 2.607206553242305, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": 0.006, \"times_seen\": 13.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": 0.06667799110246451, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"A\", \"escape\": 0.052357545340143155, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1028, \"times_seen\": 31.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.005802275357192009, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.02582546645915681, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1304, \"times_seen\": 9.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"E\", \"escape\": -0.14450038860263106, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0618, \"times_seen\": 26.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.03857981607767862, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.0232, \"times_seen\": 28.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"G\", \"escape\": -0.06225774603517342, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0356, \"times_seen\": 17.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.050386901923764875, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0028, \"times_seen\": 26.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": 1.3496395810628563, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.3911, \"times_seen\": 48.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"K\", \"escape\": 0.011747223892478923, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.849, \"times_seen\": 3.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.03950515548702824, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1459, \"times_seen\": 48.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"M\", \"escape\": 0.009116161494228335, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1332, \"times_seen\": 14.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.30401504952921926, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0985, \"times_seen\": 64.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"P\", \"escape\": 0.009724677039043098, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.004, \"times_seen\": 8.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"escape\": -0.23763749203911688, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.1512, \"times_seen\": 11.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"R\", \"escape\": -0.014224134647487032, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.9894, \"times_seen\": 7.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -0.15551582077158557, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0133, \"times_seen\": 73.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"T\", \"escape\": -0.2855946452082607, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.047, \"times_seen\": 50.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"V\", \"escape\": 0.03625572195712111, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.0001, \"times_seen\": 47.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"W\", \"escape\": 1.8126619241405122, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.376, \"times_seen\": 27.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.016292265995290166, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.8664, \"times_seen\": 3.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.010771958463117926, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -2.6212, \"times_seen\": 1.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.039472284379708185, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -2.936, \"times_seen\": 2.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.02928714047005538, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -0.1043, \"times_seen\": 7.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.01843335192535772, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -2.1212, \"times_seen\": 1.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.00038430922802949497, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -3.0563, \"times_seen\": 1.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.001964711513183051, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.0538, \"times_seen\": 10.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.0037387161628714685, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.3375, \"times_seen\": 1.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.03735059517619987, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.1554, \"times_seen\": 12.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.0073521480800777484, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.7935, \"times_seen\": 8.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.006795248097094383, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.1889, \"times_seen\": 10.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.004543007021946317, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.1482, \"times_seen\": 16.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.017338175757162125, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.1088, \"times_seen\": 8.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.02461493463646102, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -2.5791, \"times_seen\": 1.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.3376398589897124, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.2888, \"times_seen\": 82.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 1.4408803106827346, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.2675, \"times_seen\": 5.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.043444348193370744, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.7602, \"times_seen\": 2.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.03504322072847736, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.1053, \"times_seen\": 34.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.0024034536035775008, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.6904, \"times_seen\": 12.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"A\", \"escape\": 0.5864457180248142, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.0962, \"times_seen\": 17.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"C\", \"escape\": -0.00550847758525462, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -2.6374, \"times_seen\": 3.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": -0.18244682184648714, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.2021, \"times_seen\": 20.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"E\", \"escape\": -0.004119918488742368, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.1255, \"times_seen\": 4.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"F\", \"escape\": -2.8401222188242974, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1583, \"times_seen\": 17.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"G\", \"escape\": -0.06691424724932589, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.7695, \"times_seen\": 9.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"I\", \"escape\": -0.005625558040654314, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.8906, \"times_seen\": 1.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"K\", \"escape\": -0.02446330266520697, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.9618, \"times_seen\": 6.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": -0.08391330531395007, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.0845, \"times_seen\": 39.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"M\", \"escape\": -0.03225798076547943, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.2724, \"times_seen\": 6.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.05094851696624813, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1694, \"times_seen\": 24.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": -0.0020451464391458576, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -2.9748, \"times_seen\": 11.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": -0.060066381842203934, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.0357, \"times_seen\": 27.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.16703954031221652, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.0928, \"times_seen\": 58.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": -0.0490701795806177, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.3556, \"times_seen\": 23.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"T\", \"escape\": -0.04579279323425235, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.0339, \"times_seen\": 10.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"V\", \"escape\": -0.021702345635731753, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.2803, \"times_seen\": 6.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"W\", \"escape\": -0.003078634236958472, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1674, \"times_seen\": 7.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.4252561086069341, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1237, \"times_seen\": 40.0}, {\"site\": 503, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.0011377905687996832, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -2.8214, \"times_seen\": 1.0}, {\"site\": 503, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.0003394728591761715, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -3.1158, \"times_seen\": 1.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.006199124068079058, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -1.0223, \"times_seen\": 3.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.0023443318707458936, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -2.8046, \"times_seen\": 1.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.02673903697836248, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -2.3546, \"times_seen\": 2.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0018212349554225474, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -1.6578, \"times_seen\": 1.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.027295641232382165, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -0.9961, \"times_seen\": 5.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.003417874380253146, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.0169, \"times_seen\": 1.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.006928382700185783, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.1304, \"times_seen\": 11.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.003271588241809594, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.0059548936831214485, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -1.0566, \"times_seen\": 1.0}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.008935614757331642, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.951, \"times_seen\": 1.0}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.0314940156718442, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -1.815, \"times_seen\": 2.0}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.0006628456954606738, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.8316, \"times_seen\": 1.0}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.0029814425691843103, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.9775, \"times_seen\": 1.0}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.017755213961512646, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -0.8584, \"times_seen\": 4.0}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0544303676590466, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.6987, \"times_seen\": 5.0}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.004196193537374065, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -1.5842, \"times_seen\": 1.0}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.018343880880887797, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -1.2286, \"times_seen\": 3.0}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.021824735523260717, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -1.83, \"times_seen\": 2.0}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.002596909877257111, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -1.3902, \"times_seen\": 7.0}, {\"site\": 509, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.007723695756534598, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -1.3994, \"times_seen\": 4.0}, {\"site\": 509, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0031893017278386304, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.8254, \"times_seen\": 1.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.02964921086669165, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -0.3652, \"times_seen\": 11.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.006547490291306252, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -1.4701, \"times_seen\": 2.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.017602776015351058, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -0.38, \"times_seen\": 9.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.01138073891528559, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.8942, \"times_seen\": 5.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.003700414080892633, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -0.8287, \"times_seen\": 1.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.0035436065180196865, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.4129, \"times_seen\": 1.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.024614419620693214, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -1.5414, \"times_seen\": 4.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0041605778955927895, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -0.8028, \"times_seen\": 1.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.04185439757992687, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -1.7083, \"times_seen\": 15.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.01498716517799701, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": 0.0622, \"times_seen\": 10.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.023611659681104135, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -0.1658, \"times_seen\": 24.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.03564619284987888, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -1.2422, \"times_seen\": 23.0}, {\"site\": 512, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.004638992699348885, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -0.3377, \"times_seen\": 12.0}, {\"site\": 512, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.00764363785244345, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.6288, \"times_seen\": 5.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -2.5764289217731743e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.8865, \"times_seen\": 1.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.026438515831687572, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.6653, \"times_seen\": 5.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.009944216842217619, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -1.2325, \"times_seen\": 26.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.007047984805743389, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.1296, \"times_seen\": 20.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": -0.0022250138055588432, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.5221, \"times_seen\": 3.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": 0.016407710421368245, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -1.7671, \"times_seen\": 1.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.017974588528965732, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": 0.1757, \"times_seen\": 29.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.008358763510891109, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.6957, \"times_seen\": 12.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.07893691340630198, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": 0.1283, \"times_seen\": 32.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.005077592468516009, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.1504, \"times_seen\": 3.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 1.697544943569345, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -1.4089, \"times_seen\": 2.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.01821317476790648, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -1.2135, \"times_seen\": 2.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.002910140130974471, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -2.1178, \"times_seen\": 5.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.02034380541893669, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.8606, \"times_seen\": 8.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.04744502103016936, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.0136, \"times_seen\": 66.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.008907639501908192, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.9741, \"times_seen\": 7.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.05876738208954541, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.19, \"times_seen\": 20.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.020426755786432178, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.1959, \"times_seen\": 22.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.007284346784178736, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.124, \"times_seen\": 7.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.02805722802420209, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.3749, \"times_seen\": 14.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.008615819991149836, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.5652, \"times_seen\": 10.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0056954398392949366, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.0737, \"times_seen\": 5.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": -0.04622770748220412, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.6861, \"times_seen\": 35.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": 0.043810256221378456, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.7408, \"times_seen\": 21.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": -0.034359729540647956, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.1239, \"times_seen\": 21.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": -0.0582865159164686, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.0534, \"times_seen\": 14.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.021696814571454146, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -1.268, \"times_seen\": 9.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"V\", \"escape\": 0.01679434319393024, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.6903, \"times_seen\": 1.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.016020462707130003, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": 0.0498, \"times_seen\": 34.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.0046307759181652575, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -0.6494, \"times_seen\": 4.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.007637590279080965, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -0.226, \"times_seen\": 9.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.6370565113530392, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.02197101772371097, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -1.6363, \"times_seen\": 9.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.06940608328688656, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -0.13, \"times_seen\": 60.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.27053892574706356, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -1.255, \"times_seen\": 30.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.006429281921855611, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -1.6988, \"times_seen\": 20.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.0018111345746964992, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -1.0538, \"times_seen\": 1.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.0003420690375089189, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.0597, \"times_seen\": 2.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.026613084160574795, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -1.6256, \"times_seen\": 13.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.03703819976209234, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.2545, \"times_seen\": 18.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.04511888094282643, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.018812269213805424, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.4019, \"times_seen\": 17.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.04171882774884344, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.3776, \"times_seen\": 22.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.01964716075384557, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.781, \"times_seen\": 25.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.11928396900510757, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3558, \"times_seen\": 33.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.028447348635951553, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3925, \"times_seen\": 15.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.01353837632795633, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.6136, \"times_seen\": 27.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.06235582358521892, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.8527, \"times_seen\": 45.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.013652079915017096, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3548, \"times_seen\": 5.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.00037788208205843374, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.092, \"times_seen\": 12.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.0038534678007016306, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -2.5438, \"times_seen\": 1.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.03175442226682578, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.747, \"times_seen\": 34.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": 0.026335566231169186, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.3471, \"times_seen\": 9.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.03491370533577458, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.8793, \"times_seen\": 6.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.05194961900363104, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": 0.1483, \"times_seen\": 44.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": -0.00941452160106967, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.8429, \"times_seen\": 3.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.03352140797535856, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -2.3261, \"times_seen\": 17.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.007447419417348639, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.2522, \"times_seen\": 76.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.05231363131400574, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.2783, \"times_seen\": 67.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.4872129927553927, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.2323, \"times_seen\": 116.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": -0.008800059528623947, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3283, \"times_seen\": 3.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.04045883418679603, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": 0.0691, \"times_seen\": 15.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.003580733073930628, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.9549, \"times_seen\": 1.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.17456453504054364, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -0.4663, \"times_seen\": 46.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.02243673526974824, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -1.99, \"times_seen\": 17.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.0037259183910842864, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -2.2485, \"times_seen\": 1.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.1351034126760488, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -0.7974, \"times_seen\": 28.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.0038034971519964426, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.04146725554855744, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": 0.2301, \"times_seen\": 14.0}, {\"site\": 521, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.0034106893342918756, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 521, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.00375249060699781, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -2.1667, \"times_seen\": 1.0}, {\"site\": 522, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": -0.003231356930952822, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -0.9191, \"times_seen\": 1.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.002871307587990963, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -0.6305, \"times_seen\": 2.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0018731773960888108, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -1.0706, \"times_seen\": 2.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": -0.008543121926168979, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -0.6872, \"times_seen\": 3.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.0032665647393229345, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -2.7353, \"times_seen\": 1.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.002792188298911855, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -2.1818, \"times_seen\": 1.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"K\", \"escape\": -0.01201111639123005, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -0.785, \"times_seen\": 2.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.7955696424426139, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -2.6974, \"times_seen\": 2.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.023405578408250714, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -1.9063, \"times_seen\": 5.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.0042557226199227225, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -1.7467, \"times_seen\": 3.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.05274498778454733, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.5715, \"times_seen\": 16.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.03654749294428375, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": 0.0142, \"times_seen\": 16.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.0041257449125946645, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -2.2802, \"times_seen\": 1.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.030490477930883157, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.0454, \"times_seen\": 10.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.01878371739804125, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.3537, \"times_seen\": 5.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.007680557526283712, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.0315, \"times_seen\": 2.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": -0.011413116441813162, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.7099, \"times_seen\": 4.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.034342114822921134, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.2878, \"times_seen\": 11.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.0048958725310353415, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.6437, \"times_seen\": 2.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.004865351599346619, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.2172, \"times_seen\": 5.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.029048440774116474, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.3064, \"times_seen\": 11.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.0006296619727915752, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.3323, \"times_seen\": 17.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.006664824384218594, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.2839, \"times_seen\": 11.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.5388912025654194, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.3896, \"times_seen\": 37.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.009761611582694608, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.0142, \"times_seen\": 7.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.01494711812920321, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -1.2372, \"times_seen\": 4.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.007285124396155169, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -0.6498, \"times_seen\": 2.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.08270255785111988, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -1.1321, \"times_seen\": 21.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.011945879374965218, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -0.5927, \"times_seen\": 6.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.00440083095832305, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -2.5076, \"times_seen\": 1.0}, {\"site\": 528, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.015949854325200824, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -2.6095, \"times_seen\": 2.0}, {\"site\": 528, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.020117375613444396, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -2.8056, \"times_seen\": 1.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.00037539016289435927, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.1006, \"times_seen\": 10.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.010312288740467216, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.1214, \"times_seen\": 3.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.011120439505583234, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -1.0965, \"times_seen\": 6.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.008335646421558065, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.0009, \"times_seen\": 11.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"P\", \"escape\": 0.05299405723337493, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.026711092166168335, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.0208, \"times_seen\": 22.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": -0.0016835369827210014, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.3049, \"times_seen\": 1.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.014576813186855695, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.1035, \"times_seen\": 5.0}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.004427274254301026, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -2.0848, \"times_seen\": 2.0}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.04472502682774107, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -1.0553, \"times_seen\": 6.0}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.041779661956667734, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -1.1578, \"times_seen\": 7.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.02909453912317791, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -1.5204, \"times_seen\": 9.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.015727154916327934, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -2.7729, \"times_seen\": 6.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.03723939722704535, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -0.0695, \"times_seen\": 28.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.017275900367544273, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -0.7782, \"times_seen\": 8.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.011053431963367727, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -1.2792, \"times_seen\": 5.0}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.0026714617340868525, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -1.3257, \"times_seen\": 1.0}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.026899300164411, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -0.6013, \"times_seen\": 12.0}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.05287047726553172, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -0.4288, \"times_seen\": 6.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.050826102210831385, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.1753, \"times_seen\": 17.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.06326081928859816, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.5918, \"times_seen\": 18.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.010067199407856718, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -1.124, \"times_seen\": 3.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.034017912229410564, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.7847, \"times_seen\": 8.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"W\", \"escape\": -0.002574808441031704, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.9078, \"times_seen\": 1.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.01619960415500901, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.9206, \"times_seen\": 5.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.021924851698432613, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -2.6262, \"times_seen\": 1.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.009402002541421862, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -1.5978, \"times_seen\": 5.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.00028643476192111904, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -2.6023, \"times_seen\": 5.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.0028992217586911143, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.5799, \"times_seen\": 2.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.008934463888984936, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.2885, \"times_seen\": 3.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.0027110026365994512, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.2944, \"times_seen\": 3.0}, {\"site\": 535, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.003488148728857849, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.9432, \"times_seen\": 1.0}, {\"site\": 535, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.003127483469575566, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.6424, \"times_seen\": 1.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0034114934258937593, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -2.5994, \"times_seen\": 1.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.003487415041707628, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -2.9985, \"times_seen\": 1.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.02028637777238665, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -0.192, \"times_seen\": 11.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0032628465069850163, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -1.9369, \"times_seen\": 1.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.00023182214387178449, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.2562, \"times_seen\": 16.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.002292990369659913, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.395, \"times_seen\": 1.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.003603670500915446, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -1.0693, \"times_seen\": 1.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.012407657828743066, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.1286, \"times_seen\": 11.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": 0.024068485591606653, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.6167, \"times_seen\": 7.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.11095608223072577, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.1715, \"times_seen\": 32.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.057634016453598814, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.232, \"times_seen\": 10.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.02823386170429194, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.5861, \"times_seen\": 14.0}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.023077417663914603, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -3.1258, \"times_seen\": 1.0}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 1.196306352792383, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.8348, \"times_seen\": 2.0}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.02234419072189536, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": 0.0416, \"times_seen\": 1.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.036172148341538916, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -0.5205, \"times_seen\": 10.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.00053457151106515, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.7926, \"times_seen\": 1.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.019175640608911994, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.9886, \"times_seen\": 1.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.09169166804319039, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.3102, \"times_seen\": 2.0}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.01665063147169728, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -1.8554, \"times_seen\": 6.0}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"T\", \"escape\": -0.0009133635000891828, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.9328, \"times_seen\": 1.0}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.0010294893974110166, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -0.5522, \"times_seen\": 1.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.028620706326516997, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -0.7887, \"times_seen\": 1.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": 0.015859872512213775, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -0.1076, \"times_seen\": 2.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.013399733089611343, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -2.0814, \"times_seen\": 2.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.01721196660410931, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.329, \"times_seen\": 8.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.04672322445732155, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.3651, \"times_seen\": 10.0}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.0035570537558476563, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.745, \"times_seen\": 1.0}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.002519701342576633, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.9644, \"times_seen\": 1.0}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": 0.010101189325261427, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -1.8548, \"times_seen\": 2.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.014774421633634204, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.01997920356555099, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": 0.2297, \"times_seen\": 4.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0015208018371671507, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": -0.6673, \"times_seen\": 3.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.002229818066770937, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": -0.3809, \"times_seen\": 5.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": -0.06025975456138343, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3784, \"times_seen\": 19.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": -0.008187480062704313, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.4923, \"times_seen\": 2.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.03228175016196136, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.4994, \"times_seen\": 26.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": -0.012320328681086954, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.7061, \"times_seen\": 4.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.036727361260420775, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.9731, \"times_seen\": 10.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.1312503115429607, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.5209, \"times_seen\": 11.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -1.0183987692550414, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.2457, \"times_seen\": 27.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.06123929952259736, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.8051, \"times_seen\": 18.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.3983435481607013, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3205, \"times_seen\": 18.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.7450608282063046, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.3329, \"times_seen\": 20.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": -0.019170139293372836, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -2.1393, \"times_seen\": 6.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.025146184037487765, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.1241, \"times_seen\": 10.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.01692835207935453, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": 0.0268, \"times_seen\": 42.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.02712858064807192, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3465, \"times_seen\": 18.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.0544957572952397, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3819, \"times_seen\": 29.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.03656229542405928, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.4142, \"times_seen\": 13.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": -0.012668955062641948, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.8383, \"times_seen\": 4.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": -0.9051126539253291, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.3953, \"times_seen\": 5.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": -0.011617561140642382, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -2.6006, \"times_seen\": 4.0}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.013215510023394925, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.5715, \"times_seen\": 4.0}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.003961120930079069, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.5343, \"times_seen\": 1.0}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.011349151550187009, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.9045, \"times_seen\": 2.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.5455277141350289, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.425, \"times_seen\": 31.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.05074547130879877, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.1083, \"times_seen\": 43.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.012041289849574784, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.3882, \"times_seen\": 9.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.008356351083580932, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -2.7505, \"times_seen\": 2.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.013758628270216181, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.6592, \"times_seen\": 10.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.007959930571091105, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.4187, \"times_seen\": 2.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.0023900831036096242, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -0.8664, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.002951851070340302, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -1.8394, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.0009632720690941418, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.7216, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.0005278930201872583, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.4634, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": 0.017710301137273628, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.8942, \"times_seen\": 1.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.007579203989546162, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -1.1944, \"times_seen\": 3.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.01769414586527044, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -0.3624, \"times_seen\": 8.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"K\", \"escape\": 0.027420596564615818, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -1.7071, \"times_seen\": 4.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.008458867957759963, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -0.4589, \"times_seen\": 10.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"W\", \"escape\": 0.002394993172840562, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -2.2832, \"times_seen\": 3.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.006141207550658979, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.7077, \"times_seen\": 1.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.008037821427802872, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -0.2605, \"times_seen\": 3.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.016023426933524668, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.5107, \"times_seen\": 4.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.41901247987884715, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.3878, \"times_seen\": 4.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.016670126108607637, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -1.0027, \"times_seen\": 8.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.0018264832642260341, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.3807, \"times_seen\": 6.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.0009464821292347855, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -2.9624, \"times_seen\": 1.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.08990041626736167, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.3628, \"times_seen\": 16.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.0035523688295679575, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -0.9838, \"times_seen\": 10.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.0038777950435228956, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -0.9395, \"times_seen\": 1.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.000530315668443934, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.3033, \"times_seen\": 1.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.00656216885499891, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -0.3906, \"times_seen\": 3.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.0037805591509375357, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.8571, \"times_seen\": 2.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.019841627288754257, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": 0.3314, \"times_seen\": 9.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.09769656283407183, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.0665, \"times_seen\": 22.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.06209559040789988, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.3478, \"times_seen\": 28.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.014121341747106666, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.0396, \"times_seen\": 25.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"L\", \"escape\": -0.012373480753394013, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.8793, \"times_seen\": 3.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.02603012944450635, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.2673, \"times_seen\": 8.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -0.028922256653823145, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.203, \"times_seen\": 8.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": 0.006333083645251714, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.2402, \"times_seen\": 1.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.03711778556301887, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.5543, \"times_seen\": 21.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"W\", \"escape\": -0.0049625030777828575, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -2.6839, \"times_seen\": 2.0}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.00474290197463373, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.00044588498473325654, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.2021, \"times_seen\": 1.0}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.008234644646546982, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.7942, \"times_seen\": 1.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.7714503252039188, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.5338, \"times_seen\": 13.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.008307894166221587, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.7417, \"times_seen\": 10.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.05627425920432933, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": 0.306, \"times_seen\": 34.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"P\", \"escape\": -0.026046366804274985, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.7034, \"times_seen\": 8.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.23366719346625509, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.1276, \"times_seen\": 28.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.010561138248100344, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.0048, \"times_seen\": 8.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": -0.010312390681101737, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.371, \"times_seen\": 3.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.0007021005473856466, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.3633, \"times_seen\": 9.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.003781556532086073, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -1.5022, \"times_seen\": 1.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.026107813783905684, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.5659, \"times_seen\": 1.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.011627158406199002, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -0.1764, \"times_seen\": 2.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.17182387080455566, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.1692, \"times_seen\": 2.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.010646555863764154, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -1.6942, \"times_seen\": 7.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.004643703096886626, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.1471, \"times_seen\": 5.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.025033822806183416, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.3473, \"times_seen\": 37.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": -0.0034016000763993615, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.0113, \"times_seen\": 1.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.00014583003523407364, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.0286, \"times_seen\": 1.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.01827835071725729, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.0761, \"times_seen\": 29.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.006126488697921133, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.2543, \"times_seen\": 3.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": 0.016359004231332915, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -2.0137, \"times_seen\": 2.0}, {\"site\": 556, \"wildtype\": \"F\", \"mutant\": \"G\", \"escape\": 0.0019174002617730341, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.94, \"times_seen\": 1.0}, {\"site\": 556, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.01814020965874821, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.0562, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.01460439817805505, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -2.3067, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": -0.004107260987473962, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -2.8505, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0212219685885353, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": 0.0426, \"times_seen\": 22.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.023503522960347037, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -2.8971, \"times_seen\": 8.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.004809685779253431, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -0.1031, \"times_seen\": 9.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.00024601346954276297, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": 0.0248, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.015424855238476467, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -1.37, \"times_seen\": 4.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": -0.027075872305061813, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -1.0651, \"times_seen\": 6.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.006106435191330475, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.3296, \"times_seen\": 4.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": 0.008806961216797131, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.5628, \"times_seen\": 1.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 2.00652685837237, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.3695, \"times_seen\": 8.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.0020215545197150085, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -2.3594, \"times_seen\": 5.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.012955638080644037, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.5895, \"times_seen\": 3.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.019782232707639298, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.3134, \"times_seen\": 21.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0019674832817520847, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.603, \"times_seen\": 3.0}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.0021129961268589823, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -2.9764, \"times_seen\": 2.0}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"W\", \"escape\": -0.009264191344918196, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.003737240799552501, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -2.777, \"times_seen\": 1.0}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.002466016058239932, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.927, \"times_seen\": 1.0}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.003852622670440318, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.9788, \"times_seen\": 1.0}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.0034056288237662336, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.3202, \"times_seen\": 1.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.08659365141565697, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -2.4726, \"times_seen\": 5.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.0195971870403182, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": 0.2282, \"times_seen\": 5.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.022479073715779962, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -1.6206, \"times_seen\": 4.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.04191984391969047, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -0.7601, \"times_seen\": 8.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.006527810394138469, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -2.4087, \"times_seen\": 1.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.004795023804263978, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -1.592, \"times_seen\": 3.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.004031400786712746, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": 0.2389, \"times_seen\": 2.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.00618543344925537, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -0.4081, \"times_seen\": 10.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.03852935284680612, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -0.9586, \"times_seen\": 3.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.005085289007693709, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": 0.2013, \"times_seen\": 7.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.006814326919975906, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -0.0016, \"times_seen\": 6.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.02882020643389087, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -1.6099, \"times_seen\": 7.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.5373760758826073, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -2.1732, \"times_seen\": 2.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.08928845034791129, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -0.7948, \"times_seen\": 21.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.010740896647298945, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.01793458069249177, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -2.5503, \"times_seen\": 9.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": 0.0029130838676710343, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.1, \"times_seen\": 11.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.60256732118856, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": 0.0704, \"times_seen\": 30.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.005198847495678243, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.4411, \"times_seen\": 11.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": -0.0018294401021202572, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.3508, \"times_seen\": 4.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.1225621619986852, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -1.2128, \"times_seen\": 8.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": 8.525019478660267e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.1585, \"times_seen\": 3.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": -0.0017066835419488244, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.006550152086415897, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -1.9319, \"times_seen\": 3.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.008533643031092029, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -1.7188, \"times_seen\": 8.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.017017113856767574, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -2.0757, \"times_seen\": 9.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": -0.003504928799036038, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.016942018453942623, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -1.2127, \"times_seen\": 11.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.01824990742640384, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": 0.0508, \"times_seen\": 7.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.008929736107355982, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.8953, \"times_seen\": 9.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.005748777159414993, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.4726, \"times_seen\": 6.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.005557620301661317, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.0367, \"times_seen\": 23.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.003355386572636754, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.06849601980256395, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.8571, \"times_seen\": 7.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.03683124437976257, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.3645, \"times_seen\": 13.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.0037688475425641118, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.8609, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": 0.007750807098165362, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.2365, \"times_seen\": 14.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.12428328954483207, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -1.323, \"times_seen\": 63.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.0054165920941381855, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.6726, \"times_seen\": 2.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": 0.07680568152368371, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.3606, \"times_seen\": 8.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": 0.023826883622578992, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.0229, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.036175040748070125, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.2957, \"times_seen\": 14.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": 0.00796954009161208, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.9093, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.001844515160854447, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.6227, \"times_seen\": 2.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.008702743500189417, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.4414, \"times_seen\": 7.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": -0.014225308190220082, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.5472, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 7.682307956960428e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.621, \"times_seen\": 11.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.7115311873658563, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -0.1169, \"times_seen\": 140.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.29982216166747677, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": 0.0316, \"times_seen\": 138.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.4497515242167194, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -1.4471, \"times_seen\": 88.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": -0.006047259168740428, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.4598, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.026607898031013374, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -1.6172, \"times_seen\": 34.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.00041454093927659034, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.7409, \"times_seen\": 2.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": -0.0029173670482813365, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.03396471956057213, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -0.0272, \"times_seen\": 14.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.031645422696949, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": 0.0333, \"times_seen\": 23.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.014378479296129953, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -3.0583, \"times_seen\": 2.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.56272750049026, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -2.0572, \"times_seen\": 20.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.025278738310604076, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.1502, \"times_seen\": 45.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.01645821610437322, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.1717, \"times_seen\": 13.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": 0.017529894007472402, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2113, \"times_seen\": 7.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": 0.005219892316614536, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2738, \"times_seen\": 12.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.0303330801521672, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.1425, \"times_seen\": 5.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.16432602139925623, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.3767, \"times_seen\": 51.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.8979549260846282, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.3283, \"times_seen\": 17.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.04036737897074584, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2776, \"times_seen\": 28.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.9709805201587601, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.401, \"times_seen\": 12.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.06741064588086619, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.1166, \"times_seen\": 24.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": -0.025689974403614285, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.0921, \"times_seen\": 16.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.00030014869398839483, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2249, \"times_seen\": 48.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.008606467285879632, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -2.7875, \"times_seen\": 2.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.0117452353598886, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.3372, \"times_seen\": 13.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.14740253805303147, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.6641, \"times_seen\": 53.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.062092031191325246, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.1456, \"times_seen\": 57.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.0826014366196242, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.7735, \"times_seen\": 19.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": 0.02959890968836695, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.502, \"times_seen\": 13.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.01983685845151286, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.0262, \"times_seen\": 19.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.01610225322316255, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -2.7558, \"times_seen\": 1.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.007230852871523935, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.4135, \"times_seen\": 8.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.025336886548805344, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": 0.2755, \"times_seen\": 31.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.012088577252355905, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.3074, \"times_seen\": 3.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.010237689632653476, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": 0.2203, \"times_seen\": 4.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.0022561751992784913, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -2.1183, \"times_seen\": 1.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.004484424816702197, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.024869241002521716, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -1.7645, \"times_seen\": 6.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.06567776148309407, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": 0.397, \"times_seen\": 41.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.012223190183311259, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -0.6174, \"times_seen\": 5.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.01816762504778579, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -2.0659, \"times_seen\": 16.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.002265040832153037, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -2.1062, \"times_seen\": 7.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.9534780773375244, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": 0.1167, \"times_seen\": 57.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.025666905715720195, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -1.6023, \"times_seen\": 29.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.006502998135582884, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -2.2746, \"times_seen\": 11.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0018369462432823668, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -2.0367, \"times_seen\": 1.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.0005640014555248873, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -2.8705, \"times_seen\": 1.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.01274561689187011, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": 0.2586, \"times_seen\": 25.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.01990492765973041, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -0.7482, \"times_seen\": 4.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.007146751838108149, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -1.4259, \"times_seen\": 4.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.0030063236112999278, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.4292, \"times_seen\": 5.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.012704173634673637, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -0.2346, \"times_seen\": 17.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.03880660218175281, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -1.9766, \"times_seen\": 2.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.015362130049756357, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.1163, \"times_seen\": 10.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.004916706801810217, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.9583, \"times_seen\": 2.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.003902871262638542, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -1.2552, \"times_seen\": 1.0}, {\"site\": 575, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.004437899658164787, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -2.333, \"times_seen\": 2.0}, {\"site\": 576, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.002366649601759174, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -0.8443, \"times_seen\": 1.0}, {\"site\": 576, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.017690038160060522, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -2.2045, \"times_seen\": 1.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.0068617646533330225, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -0.9949, \"times_seen\": 5.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.05931333286067127, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -1.1274, \"times_seen\": 22.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.003312340903412518, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -0.185, \"times_seen\": 9.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.07194195360025288, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": 0.0657, \"times_seen\": 53.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"M\", \"escape\": -0.02626730284844909, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": 0.2053, \"times_seen\": 5.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.09003844834027794, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -0.0238, \"times_seen\": 44.0}, {\"site\": 578, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.010591458325060222, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": -2.5045, \"times_seen\": 5.0}, {\"site\": 578, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.04116162689545132, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": -0.5312, \"times_seen\": 20.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.7732215242799932, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.0603, \"times_seen\": 48.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.014276753898638698, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.3607, \"times_seen\": 3.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.00736278363983889, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": -0.0263, \"times_seen\": 2.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.023654062000076557, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.3336, \"times_seen\": 6.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.028595248062766216, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": -3.2007, \"times_seen\": 1.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.010335506045034394, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.1563, \"times_seen\": 3.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.01771461884098674, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.0418, \"times_seen\": 15.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.005381040041152893, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -2.4049, \"times_seen\": 2.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.024536814692059677, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.3008, \"times_seen\": 17.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"L\", \"escape\": -0.0035172810907817976, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -3.0176, \"times_seen\": 1.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.043247464349693426, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -0.8469, \"times_seen\": 12.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.008714543750407434, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -2.1047, \"times_seen\": 4.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.014754212958665414, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -2.627, \"times_seen\": 1.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.009356668782854797, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -2.6452, \"times_seen\": 3.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.002247417359058704, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -2.0253, \"times_seen\": 1.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.01653215134864332, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": 0.3752, \"times_seen\": 9.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.001658926527260168, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -1.1432, \"times_seen\": 16.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.11932984669255559, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -0.1092, \"times_seen\": 11.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.016978756073692477, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.00727533852687544, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -0.8359, \"times_seen\": 14.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.002662783660066355, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.026627954003314705, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.4963, \"times_seen\": 6.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.005302523768571527, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.31, \"times_seen\": 2.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.032224929359292824, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -0.2218, \"times_seen\": 14.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.015616170476527845, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -0.7711, \"times_seen\": 6.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.003396812867476219, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -0.6072, \"times_seen\": 3.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.013356792025248513, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -2.9842, \"times_seen\": 2.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"G\", \"escape\": -0.0026068498615371832, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -2.9847, \"times_seen\": 1.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.00893718720648438, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -1.7824, \"times_seen\": 2.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.0050793446563726944, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -2.7277, \"times_seen\": 1.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0030856663888350743, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -2.2331, \"times_seen\": 2.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.008165629235445017, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -1.6721, \"times_seen\": 3.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.07059097594349849, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.7151, \"times_seen\": 14.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.6525271927087304, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -1.1483, \"times_seen\": 22.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.030591631453510237, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.6462, \"times_seen\": 10.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.00971261318421251, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": 0.0031, \"times_seen\": 3.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.009413319879664176, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.4023, \"times_seen\": 5.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.009479981336987962, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.4268, \"times_seen\": 5.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.0030258957656867746, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.8352, \"times_seen\": 1.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.0059055612790572766, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.9777, \"times_seen\": 2.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.0009386806379845882, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.5671, \"times_seen\": 2.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.026810797999921223, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.3969, \"times_seen\": 5.0}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.00454170094273177, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9043, \"times_seen\": 1.0}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.008694718137930376, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9197, \"times_seen\": 3.0}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.0033977796533154543, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9917, \"times_seen\": 1.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.026591794287077707, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -0.3383, \"times_seen\": 4.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0011736882557706028, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -0.936, \"times_seen\": 1.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.023443806901659446, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.3641, \"times_seen\": 28.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.026940241163284247, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": 0.07, \"times_seen\": 6.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.004201877874723199, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.8018, \"times_seen\": 2.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.015346561335177786, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.303, \"times_seen\": 6.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.026332603722937616, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -0.2819, \"times_seen\": 10.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.0020640646903402333, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.843, \"times_seen\": 3.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.717473668157672, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.971, \"times_seen\": 2.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.017607635564108656, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.4882, \"times_seen\": 4.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"P\", \"escape\": -0.005554380645254185, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.8179, \"times_seen\": 1.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.0034610102148109963, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -0.25, \"times_seen\": 20.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.033375606278891044, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -0.2666, \"times_seen\": 2.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.004128604762283156, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.2492, \"times_seen\": 1.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0040327246948110625, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -2.9055, \"times_seen\": 1.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.023180182117390407, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -2.2234, \"times_seen\": 8.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.011487620145633638, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.7069, \"times_seen\": 5.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.06347858297202925, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.6035, \"times_seen\": 7.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.0038496492697099754, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -1.2151, \"times_seen\": 5.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.001326078010055029, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -0.7032, \"times_seen\": 10.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": 0.008443745840281952, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -0.9029, \"times_seen\": 6.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.004901659907177842, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -0.7007, \"times_seen\": 17.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.0026360026493263684, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": 0.0355, \"times_seen\": 13.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.0025040863027567277, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -2.1905, \"times_seen\": 6.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.005710727087611189, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -1.4738, \"times_seen\": 1.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": 0.0011643703626488602, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -2.0412, \"times_seen\": 2.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.020522518376527535, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.8661, \"times_seen\": 1.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.019505316122521033, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -2.6389, \"times_seen\": 1.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.0017189989659146308, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.5895, \"times_seen\": 1.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.032026594834488636, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.1331, \"times_seen\": 6.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.003337970667161641, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.7692, \"times_seen\": 5.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.004459126930495006, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -3.0332, \"times_seen\": 2.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.004838846332297041, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -0.0969, \"times_seen\": 2.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.008625696187302719, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -1.042, \"times_seen\": 7.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.0081736379611288, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -0.651, \"times_seen\": 3.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.009959200625368187, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -2.2683, \"times_seen\": 3.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.013298556945279904, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -0.941, \"times_seen\": 4.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.004165486671803675, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -1.3007, \"times_seen\": 4.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.0059781641788764234, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.024598078988164632, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -1.4555, \"times_seen\": 2.0}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0028983761958122616, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -1.6931, \"times_seen\": 2.0}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.030399420135342102, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -0.7923, \"times_seen\": 7.0}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.00293466950283911, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -1.8609, \"times_seen\": 1.0}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.004356574802397859, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -1.5147, \"times_seen\": 1.0}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0029091972341566416, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -2.1948, \"times_seen\": 1.0}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.003769920108567924, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -0.7859, \"times_seen\": 17.0}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.006299207408402896, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.4833, \"times_seen\": 2.0}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.04873076523872385, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -1.9985, \"times_seen\": 11.0}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.0034198842000736297, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.6961, \"times_seen\": 1.0}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.018253495388043287, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": 0.3906, \"times_seen\": 2.0}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.011019103834590021, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.586, \"times_seen\": 5.0}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.006537187103294432, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.9757, \"times_seen\": 2.0}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.003164242170159249, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.8966, \"times_seen\": 1.0}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.0013888215095035823, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -2.6823, \"times_seen\": 1.0}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.012039171011114246, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -3.0564, \"times_seen\": 4.0}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": -0.0029889002535334946, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -2.9556, \"times_seen\": 1.0}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.008163499669801273, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -1.4786, \"times_seen\": 1.0}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.003753383892298017, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -2.3935, \"times_seen\": 1.0}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.003675493417314842, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -0.1275, \"times_seen\": 1.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.008932194341651151, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.1276, \"times_seen\": 8.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.0015761742562923797, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.5201, \"times_seen\": 9.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.013397885196394607, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.5396, \"times_seen\": 6.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.01795039584622732, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.0118, \"times_seen\": 13.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": -0.003564211118282339, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.0945, \"times_seen\": 1.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.04905357805594168, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.2211, \"times_seen\": 19.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.015713008801598097, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.2757, \"times_seen\": 20.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.03254830509843271, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": -0.1977, \"times_seen\": 32.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.021658041156855143, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": 0.0939, \"times_seen\": 76.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.027938515982134104, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": -0.4228, \"times_seen\": 44.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.004480863784947058, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": -0.5434, \"times_seen\": 2.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.004486682941612969, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": 0.0637, \"times_seen\": 6.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0015070091918565212, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -1.6258, \"times_seen\": 8.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.003183543655890176, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -1.3301, \"times_seen\": 2.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.004863239376765134, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -2.9726, \"times_seen\": 1.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.005115006766708139, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -1.7384, \"times_seen\": 6.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.004351852429754824, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": 0.1573, \"times_seen\": 1.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0064100667403700524, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -2.5998, \"times_seen\": 3.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.010466762570474486, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": 0.0398, \"times_seen\": 19.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.04213773763350773, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.9545, \"times_seen\": 7.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": -0.0027862748022064116, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.7121, \"times_seen\": 1.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.05158930237878808, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.0215, \"times_seen\": 10.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.002427771265983212, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.4306, \"times_seen\": 17.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.003353011858576172, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -1.1502, \"times_seen\": 6.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.04449349616387233, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.374, \"times_seen\": 56.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.06814666268151708, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.0725, \"times_seen\": 54.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.01807597038237764, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.1144, \"times_seen\": 16.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.003815556595016561, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.2201, \"times_seen\": 38.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"V\", \"escape\": -0.05512247436633098, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": 0.0911, \"times_seen\": 15.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.00453110910067887, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -2.9643, \"times_seen\": 1.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": -0.005738333887984263, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -0.6953, \"times_seen\": 2.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.006596647993775866, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -0.2404, \"times_seen\": 7.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.01995405228117979, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -0.1307, \"times_seen\": 20.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.018326542101009518, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.08724637013342951, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.4976, \"times_seen\": 7.0}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.002827549857109142, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.2921, \"times_seen\": 2.0}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.000673357542850497, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.7193, \"times_seen\": 5.0}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.005798493632852975, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -0.3049, \"times_seen\": 3.0}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.011366412787331883, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -1.1414, \"times_seen\": 12.0}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.017029653245217678, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -2.8599, \"times_seen\": 1.0}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.5964424052138431, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -0.9023, \"times_seen\": 84.0}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.00911266967803956, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -1.4612, \"times_seen\": 4.0}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.00447848210492989, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -2.9813, \"times_seen\": 1.0}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0003479796705585354, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -1.9878, \"times_seen\": 2.0}, {\"site\": 609, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 6.568463858856464e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -0.6197, \"times_seen\": 6.0}, {\"site\": 609, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.003690721878910779, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9522, \"times_seen\": 1.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.034475246521946695, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -0.0633, \"times_seen\": 17.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.00625626652174328, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": 0.0786, \"times_seen\": 18.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.02937247837954498, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -1.4795, \"times_seen\": 11.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.01946842434611092, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -1.6206, \"times_seen\": 5.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.008670923672198565, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -1.1987, \"times_seen\": 2.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.9738426112604684, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -0.1161, \"times_seen\": 60.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.016852417699584645, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -2.5233, \"times_seen\": 1.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.007048657971695272, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.7202, \"times_seen\": 18.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.009339869750293888, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.8353, \"times_seen\": 2.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.772006397999634, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.1259, \"times_seen\": 15.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0059674676579870144, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.4898, \"times_seen\": 3.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": 0.05574119202915938, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -3.0182, \"times_seen\": 2.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": -0.007650430195949187, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.6028, \"times_seen\": 2.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": -0.04100428033806054, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.8835, \"times_seen\": 1.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.012199075961784935, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.5818, \"times_seen\": 6.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.905316953471925, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.0809, \"times_seen\": 10.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.007040838642283164, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.0646, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -2.730681247246674, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": 0.1571, \"times_seen\": 11.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": -0.0009387653669168509, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -3.008, \"times_seen\": 1.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": 0.0030383067862767388, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.9781, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 1.155883355004116, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.5402, \"times_seen\": 21.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.20814099300769665, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.612, \"times_seen\": 38.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.07842458131899, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.6407, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.00897961653203047, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.6495, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.012949918817445434, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.742, \"times_seen\": 5.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.003910546657495785, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.5617, \"times_seen\": 1.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.028538331547546054, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -0.5794, \"times_seen\": 13.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.0039875943499733555, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.0013096751267434323, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -1.6823, \"times_seen\": 6.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.01545719799849712, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": 0.0285, \"times_seen\": 15.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.013784799829503753, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -0.5605, \"times_seen\": 8.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.007522884496324116, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -0.132, \"times_seen\": 26.0}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.013780394150348, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": -0.0954, \"times_seen\": 12.0}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.07565108014970812, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.045, \"times_seen\": 50.0}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": -0.008512012984395488, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.2989, \"times_seen\": 4.0}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.014167985761168723, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.0998, \"times_seen\": 9.0}, {\"site\": 614, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.0019511830796609662, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.5849, \"times_seen\": 1.0}, {\"site\": 614, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": 0.018623758045897786, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.6836, \"times_seen\": 2.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.016762695991281322, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.2089, \"times_seen\": 30.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.48113499222562006, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": -0.0548, \"times_seen\": 30.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.03117457455905695, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.2881, \"times_seen\": 13.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.045915219365436195, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.3502, \"times_seen\": 6.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.001075867815094253, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": -0.3306, \"times_seen\": 10.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.011624299778866372, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": -0.0955, \"times_seen\": 8.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.035912220378387705, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.506, \"times_seen\": 6.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.01814812865796711, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.3661, \"times_seen\": 28.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.0035626662372880533, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -1.2736, \"times_seen\": 19.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.3661042431452751, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.7037, \"times_seen\": 39.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.06731885680574465, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.3618, \"times_seen\": 15.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": 0.011664557978088007, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.6991, \"times_seen\": 4.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.036659701222290925, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -1.0595, \"times_seen\": 10.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.006528704023644125, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -2.9745, \"times_seen\": 2.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.005457718011062509, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -1.8411, \"times_seen\": 2.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.001973532353472353, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -1.49, \"times_seen\": 7.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.01728741477514616, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -1.9799, \"times_seen\": 4.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.00831007653118638, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": 0.2404, \"times_seen\": 2.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"G\", \"escape\": -0.009475067698154595, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.185, \"times_seen\": 1.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.06209992077188452, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.2754, \"times_seen\": 13.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -1.1335238649247266, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -1.4398, \"times_seen\": 9.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.014821674965430718, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.8676, \"times_seen\": 2.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.026145159626877048, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": 0.0839, \"times_seen\": 21.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.028311724696780553, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.8725, \"times_seen\": 11.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.09916217263170346, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.2054, \"times_seen\": 74.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.05419931440764977, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.7004, \"times_seen\": 16.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": -0.040328271595504644, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.1215, \"times_seen\": 25.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.04785181793142809, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0828, \"times_seen\": 46.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.48991839936712034, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0222, \"times_seen\": 48.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.3785133912844339, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.3922, \"times_seen\": 90.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"H\", \"escape\": 0.0003859420516083799, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0315, \"times_seen\": 9.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.033583530788427296, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0573, \"times_seen\": 17.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"K\", \"escape\": 0.006016365702667584, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.264, \"times_seen\": 19.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.19918599415142094, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0054, \"times_seen\": 110.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.05465347704038156, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0884, \"times_seen\": 33.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"N\", \"escape\": 0.024306866356674603, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.078, \"times_seen\": 19.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"P\", \"escape\": -0.001296163949615076, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.457, \"times_seen\": 24.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": -0.0025650572855043558, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0915, \"times_seen\": 20.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": -1.2193044889393074, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.3886, \"times_seen\": 66.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.0872415510822796, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.1195, \"times_seen\": 47.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.007330812702663552, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0777, \"times_seen\": 22.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"W\", \"escape\": 0.04903051572681427, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0497, \"times_seen\": 19.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.20360455071005523, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0704, \"times_seen\": 15.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"*\", \"escape\": -0.0027912916439630044, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -2.9006, \"times_seen\": 1.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.007270724719588991, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": 0.2509, \"times_seen\": 2.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.0721412157800027, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -0.1413, \"times_seen\": 17.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.005361576153750834, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -0.205, \"times_seen\": 43.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.019982762916322904, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -0.3156, \"times_seen\": 48.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.004437721172975181, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.197, \"times_seen\": 1.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.006314966810839848, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.3237, \"times_seen\": 3.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0005588351334895139, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": -1.5897, \"times_seen\": 6.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.017034888047237174, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": -0.3589, \"times_seen\": 14.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": -0.06869492995112775, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": -0.6508, \"times_seen\": 5.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.0020916769876904886, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.0723, \"times_seen\": 10.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": 0.017887230076989925, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": -0.2539, \"times_seen\": 6.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.030840880519016067, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.3651, \"times_seen\": 27.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.03304971528432873, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": -1.0128, \"times_seen\": 9.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.016658396185897158, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.1853, \"times_seen\": 5.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.016397443826773512, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -2.37, \"times_seen\": 1.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.06305798494241165, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.8131, \"times_seen\": 6.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.004780354168502124, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -1.9877, \"times_seen\": 5.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.0012883391029878688, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": 0.0731, \"times_seen\": 20.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.014062616817912743, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.301, \"times_seen\": 33.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.0810492918839053, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.1941, \"times_seen\": 52.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.09805284686243754, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.0542, \"times_seen\": 8.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.062436097340121836, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": 0.2853, \"times_seen\": 32.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.031069007370956147, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.3528, \"times_seen\": 29.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.14381193626242086, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.005999827663482742, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.1129, \"times_seen\": 25.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.00022945917301400124, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": 0.3301, \"times_seen\": 1.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.0018200603136298774, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -1.169, \"times_seen\": 23.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.010208348094468167, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -0.1243, \"times_seen\": 4.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.001209760880447395, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -1.7745, \"times_seen\": 1.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.05533440483492131, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": 0.3651, \"times_seen\": 24.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.04747611366707928, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -0.5072, \"times_seen\": 30.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.031731172926334546, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -0.0393, \"times_seen\": 4.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.0039017736732595734, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": 0.2464, \"times_seen\": 1.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.006611413004037585, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -2.3288, \"times_seen\": 3.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.007351825380282506, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -2.041, \"times_seen\": 2.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.02602813748870095, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -0.1729, \"times_seen\": 6.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.007497250136063545, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": 0.0994, \"times_seen\": 4.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.0021595023356145676, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -0.4191, \"times_seen\": 13.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.016901191248570528, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -2.566, \"times_seen\": 4.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.0010476288343152426, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -3.0079, \"times_seen\": 1.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.018699766335884674, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -1.4567, \"times_seen\": 5.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.002014360355146791, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -0.2781, \"times_seen\": 6.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.030221949836309672, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.7566, \"times_seen\": 6.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.02923119627280469, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -1.2904, \"times_seen\": 14.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.008436445785362684, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.4117, \"times_seen\": 1.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.02747178912514215, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.6186, \"times_seen\": 17.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.02148010108115346, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.7441, \"times_seen\": 10.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"Y\", \"escape\": 0.024470524582748007, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -1.4315, \"times_seen\": 3.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.00853419183135926, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.2457, \"times_seen\": 23.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.003372915555139208, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.5282, \"times_seen\": 20.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.013041183224473032, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.2064, \"times_seen\": 46.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.013310906191595034, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": 0.0444, \"times_seen\": 3.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.004324635597624207, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -3.0486, \"times_seen\": 1.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": -0.006994610106056399, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -3.1025, \"times_seen\": 1.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.006917911119013006, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -2.6673, \"times_seen\": 2.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": -0.0016639676750860926, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -1.8527, \"times_seen\": 5.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.015315555706290703, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -1.3895, \"times_seen\": 7.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": -0.36021956313633907, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.1903, \"times_seen\": 4.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.026542189692480875, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.1111, \"times_seen\": 10.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.007224449057232125, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.2623, \"times_seen\": 4.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.007152097305328212, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.679, \"times_seen\": 2.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.010026247328462646, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -2.2069, \"times_seen\": 1.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.016639318069668972, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": -0.3495, \"times_seen\": 8.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.0007452915227355395, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.0355, \"times_seen\": 33.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.01605915458450522, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": -0.5959, \"times_seen\": 15.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.027006315482437017, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.0208, \"times_seen\": 39.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.006582104644050698, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.1798, \"times_seen\": 4.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.017459421158700403, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -0.1222, \"times_seen\": 7.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.02982975234728864, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -0.4859, \"times_seen\": 13.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.005946949055814209, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -1.1597, \"times_seen\": 2.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.0038979033496171897, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -2.7835, \"times_seen\": 1.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.019740048460063518, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.031573102275630746, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -0.3422, \"times_seen\": 14.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.0020375704749138676, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -1.0914, \"times_seen\": 6.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.00597755996236675, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.0202, \"times_seen\": 4.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.006910805963843962, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -2.5185, \"times_seen\": 2.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.0034904280455988275, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": -0.1178, \"times_seen\": 4.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.03751351632620804, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": -0.7965, \"times_seen\": 30.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.05269417397128934, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": 0.0897, \"times_seen\": 14.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.014784562269967105, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": -0.0527, \"times_seen\": 7.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.008252322784814288, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": 0.1727, \"times_seen\": 5.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.0143063050354794, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -0.9815, \"times_seen\": 3.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.009545045612713866, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.863, \"times_seen\": 2.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.009981046794787998, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -0.9954, \"times_seen\": 16.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.00657229209771248, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.3057, \"times_seen\": 1.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -1.056176911647677, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -0.7301, \"times_seen\": 22.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.0053822369293272795, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.3083, \"times_seen\": 3.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"Y\", \"escape\": -0.002585362179116732, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.4438, \"times_seen\": 1.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.02935889489026376, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0979, \"times_seen\": 27.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.012841677992609206, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -1.0014, \"times_seen\": 34.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -0.042640871752935794, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0859, \"times_seen\": 27.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.006271739776072556, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.1585, \"times_seen\": 7.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.010299691857975486, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.5928, \"times_seen\": 33.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.02792808043934885, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.2261, \"times_seen\": 44.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.09694461112858543, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0838, \"times_seen\": 16.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.69333457342192, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.3659, \"times_seen\": 19.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.01418837409681035, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0309, \"times_seen\": 11.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.02632495200275161, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.485, \"times_seen\": 22.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.009519422359032506, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0281, \"times_seen\": 8.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.03779832509563763, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.1217, \"times_seen\": 59.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.5617871732545191, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.7143, \"times_seen\": 41.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.015188264456399073, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0478, \"times_seen\": 11.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.17514870072989125, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.2198, \"times_seen\": 43.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.2286542573930536, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0095, \"times_seen\": 27.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.0236461471654092, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0794, \"times_seen\": 18.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.04910327868683034, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.3701, \"times_seen\": 11.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": -0.002702673325157412, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -2.6987, \"times_seen\": 1.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.0013101559026208445, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.2823, \"times_seen\": 8.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.021011886205782978, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": 0.0799, \"times_seen\": 6.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.004275061781445034, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.6825, \"times_seen\": 1.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.005517189001727612, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.1028, \"times_seen\": 13.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": -0.37672556264160023, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.0317, \"times_seen\": 5.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.10481800873962582, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.065, \"times_seen\": 29.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.817842124285947, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.1098, \"times_seen\": 17.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.34754713909259005, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": 0.2456, \"times_seen\": 8.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0033889904198784277, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.2545, \"times_seen\": 9.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.005084550436024215, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.783, \"times_seen\": 2.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.09646082997306141, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.7632, \"times_seen\": 15.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.22574439337191404, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.0204, \"times_seen\": 16.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.010734962042931175, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.2273, \"times_seen\": 20.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.051324376018530404, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.605, \"times_seen\": 6.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.049891209466981494, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.1893, \"times_seen\": 13.0}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.03198792032260184, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -0.1246, \"times_seen\": 10.0}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.013590394839260174, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -0.0159, \"times_seen\": 14.0}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.005759004969942198, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -2.1946, \"times_seen\": 1.0}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.005389788336572592, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -0.1933, \"times_seen\": 3.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.039298341594704994, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.2035, \"times_seen\": 17.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.0033868988341740525, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -2.4358, \"times_seen\": 1.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.016423239018712742, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.7004, \"times_seen\": 10.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.025317083435953347, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -2.2531, \"times_seen\": 10.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": -0.003895321312076737, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.2763, \"times_seen\": 1.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": -0.010147625510091613, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.0797, \"times_seen\": 2.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.0024311030730374285, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.343, \"times_seen\": 1.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.01584762132497064, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -1.6248, \"times_seen\": 12.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.00709835099936795, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.5189, \"times_seen\": 2.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.04429618717767985, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.6014, \"times_seen\": 4.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.011236084536616849, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.2698, \"times_seen\": 17.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": -0.02516361734146347, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.115, \"times_seen\": 16.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.009273663142037347, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.1284, \"times_seen\": 8.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": 0.27050351773118075, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.2324, \"times_seen\": 19.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.0006684624070468801, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.0412, \"times_seen\": 11.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"P\", \"escape\": 0.0014858120629770814, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.2483, \"times_seen\": 1.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 1.5391016510147693, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.1537, \"times_seen\": 12.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.003051849424713827, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.4244, \"times_seen\": 4.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": 0.00293570504349026, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.8314, \"times_seen\": 1.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.003546353453256146, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -2.0077, \"times_seen\": 4.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.004458238456251807, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -0.9453, \"times_seen\": 7.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.006126421716903236, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -1.0248, \"times_seen\": 17.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.03549673923516322, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -1.1521, \"times_seen\": 23.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -1.2997175382131583, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -0.6934, \"times_seen\": 34.0}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.002743196876494805, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -3.0583, \"times_seen\": 1.0}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.027524872452513727, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.6399, \"times_seen\": 7.0}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.0025500308021348533, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.8237, \"times_seen\": 1.0}, {\"site\": 646, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": 0.0009166970304359177, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.3547, \"times_seen\": 3.0}, {\"site\": 647, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.032946132391091947, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -1.8481, \"times_seen\": 2.0}, {\"site\": 647, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": -0.0014684498810148524, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.4623, \"times_seen\": 2.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.013852445639748055, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -1.436, \"times_seen\": 5.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0017438159191515183, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -1.2201, \"times_seen\": 1.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.011562282583228922, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": 0.0312, \"times_seen\": 16.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.007063140613748435, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -2.371, \"times_seen\": 4.0}, {\"site\": 649, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.04308719209816679, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -1.3668, \"times_seen\": 5.0}, {\"site\": 649, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.019439623428043066, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -1.6485, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.025488363683592585, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.62, \"times_seen\": 9.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.00585786469629861, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.2756, \"times_seen\": 2.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.023013942461096122, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.010864480404833367, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.7272, \"times_seen\": 2.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.003077263624029383, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.3114, \"times_seen\": 7.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.048749634608038946, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.9183, \"times_seen\": 4.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.008031441612423083, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -3.1279, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.028450900840229453, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.5903, \"times_seen\": 8.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -4.25411187384073, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.4428, \"times_seen\": 5.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.004062101464904835, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.5743, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.015778122189833405, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.9389, \"times_seen\": 7.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.010431797043892823, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -3.0575, \"times_seen\": 2.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -3.155213264853928, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.5286, \"times_seen\": 11.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.0008188383226373161, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.3997, \"times_seen\": 9.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.07662578140463468, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.2728, \"times_seen\": 27.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.02919471217937491, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -0.1762, \"times_seen\": 97.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": -0.23987336813354057, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.8587, \"times_seen\": 3.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.015096230322877274, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.8739, \"times_seen\": 4.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.02479190813892239, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.375, \"times_seen\": 7.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.013596092470464956, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -1.1807, \"times_seen\": 4.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.0019327282487411608, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0612, \"times_seen\": 49.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.036079785171856865, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0988, \"times_seen\": 16.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": 0.006794919962028901, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0751, \"times_seen\": 7.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"T\", \"escape\": 0.001173234499426094, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": 0.1148, \"times_seen\": 5.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.0007747485657636211, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0384, \"times_seen\": 26.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": 0.034278548797000215, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.7878, \"times_seen\": 4.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"A\", \"escape\": -0.03958925131939192, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.7225, \"times_seen\": 23.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.0018566997354620115, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.9318, \"times_seen\": 1.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.013961189617869477, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.3138, \"times_seen\": 3.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"E\", \"escape\": 0.01839656210172058, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.9528, \"times_seen\": 1.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.003079177585389566, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -0.1608, \"times_seen\": 15.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"G\", \"escape\": 0.032629574930345184, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.9483, \"times_seen\": 5.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.0068323635622827535, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -0.9786, \"times_seen\": 25.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.02149381097805961, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.8491, \"times_seen\": 7.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"K\", \"escape\": 0.006749519420402772, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.7056, \"times_seen\": 7.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.07325087973366169, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.0489, \"times_seen\": 17.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"M\", \"escape\": -0.04429101359172613, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.0462, \"times_seen\": 16.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.17021238317689433, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.8558, \"times_seen\": 6.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"P\", \"escape\": -0.14119124903065192, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.6151, \"times_seen\": 12.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"escape\": -0.012969708801101584, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.7885, \"times_seen\": 5.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"R\", \"escape\": -0.02228279756388015, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.6506, \"times_seen\": 25.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -0.024613386935792188, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.3491, \"times_seen\": 12.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"T\", \"escape\": 0.021578695706480983, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.4896, \"times_seen\": 5.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"V\", \"escape\": -0.09735214714211526, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.3823, \"times_seen\": 18.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"W\", \"escape\": 0.023560511232443116, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -0.2047, \"times_seen\": 17.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.003612912044926309, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.7181, \"times_seen\": 6.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.00914875560713519, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -1.2286, \"times_seen\": 7.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.019337378134687506, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -0.6411, \"times_seen\": 10.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.02115000072269667, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -0.8782, \"times_seen\": 9.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.004501052289186701, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -1.2335, \"times_seen\": 19.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": 0.020946587864778373, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -0.3178, \"times_seen\": 6.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.03453736801667062, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": 0.0139, \"times_seen\": 40.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.01835523781774805, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": 0.0081, \"times_seen\": 8.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.006653412951765675, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.2966, \"times_seen\": 12.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.006501525855106358, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.2064, \"times_seen\": 11.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.041211779253915254, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.0316, \"times_seen\": 13.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.4178564258399927, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.6074, \"times_seen\": 36.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.011278672453563, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.3327, \"times_seen\": 29.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.010953321071754002, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.1507, \"times_seen\": 8.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.01129234602396112, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.1099, \"times_seen\": 3.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.03791498344187273, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -0.0312, \"times_seen\": 23.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.011438233149883032, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.1005, \"times_seen\": 9.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.7278102317173338, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": 0.011674177496048307, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.0244, \"times_seen\": 1.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.00038316237394042066, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -0.0921, \"times_seen\": 12.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.0029905973416479597, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.6133, \"times_seen\": 5.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.003629916786051475, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -1.035, \"times_seen\": 1.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.020764130348496324, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.6814, \"times_seen\": 3.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.028090356649625444, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.324, \"times_seen\": 20.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.027429492346599898, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.881, \"times_seen\": 13.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.019545189630269966, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.081, \"times_seen\": 15.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.029553896120624784, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.666, \"times_seen\": 9.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.08109152926157477, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.0655, \"times_seen\": 17.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.13364797002668918, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.7964, \"times_seen\": 46.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.006381734782126042, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.0063, \"times_seen\": 7.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.014777014414318885, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -1.6674, \"times_seen\": 6.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.01573328340577912, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.4833, \"times_seen\": 7.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.8062362870456207, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.2119, \"times_seen\": 32.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.005213699847275498, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.8207, \"times_seen\": 8.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.015640787493936967, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.2801, \"times_seen\": 10.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.03381939705239687, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.1412, \"times_seen\": 5.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.016939641926705096, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.2856, \"times_seen\": 10.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.009963751361639824, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -2.6796, \"times_seen\": 1.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.008235696968516377, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -2.0399, \"times_seen\": 2.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.014533042723077162, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -1.9582, \"times_seen\": 1.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.005404600604705345, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -2.0971, \"times_seen\": 2.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.011962588632385276, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.0284, \"times_seen\": 4.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.005770984714310979, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.1022, \"times_seen\": 3.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.0007237744030804779, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.0753, \"times_seen\": 1.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.0068467075241938095, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.3828, \"times_seen\": 3.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": -0.0026314727329154173, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.5567, \"times_seen\": 1.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.0014034870673671214, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.9382, \"times_seen\": 1.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0026522496377860798, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.7824, \"times_seen\": 2.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.0329788045248415, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -1.5756, \"times_seen\": 3.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.0068854113510189935, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -0.2973, \"times_seen\": 2.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.007204656666830613, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -2.3295, \"times_seen\": 2.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.009537982666000647, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -1.8667, \"times_seen\": 3.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.01980376425170678, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -2.6498, \"times_seen\": 5.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.0013862008535324756, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.012972244167161895, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -0.8916, \"times_seen\": 3.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.33601073388629055, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -2.9339, \"times_seen\": 5.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.0023816501207115258, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -2.7603, \"times_seen\": 1.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.2430309480282226, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -0.2891, \"times_seen\": 24.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.003301794735318871, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -0.0997, \"times_seen\": 1.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.008068838339300806, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -2.4207, \"times_seen\": 6.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": -0.01578037871498013, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -1.6171, \"times_seen\": 4.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.004093364135085374, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -2.2662, \"times_seen\": 1.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.00629821910511926, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -0.9965, \"times_seen\": 3.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.013069306383560473, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -2.5453, \"times_seen\": 3.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.011685775429053318, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -0.4449, \"times_seen\": 8.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.005772928245668944, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": 0.3625, \"times_seen\": 4.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.0010531461915943973, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -0.0976, \"times_seen\": 23.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.029958334106237324, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -1.6351, \"times_seen\": 10.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.3352189726605748, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -0.9117, \"times_seen\": 45.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.01066121968603725, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -2.698, \"times_seen\": 1.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.0028214701294183445, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -2.4976, \"times_seen\": 1.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.01193303599524168, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -1.2803, \"times_seen\": 8.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.021606410086209275, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -1.3729, \"times_seen\": 1.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.09166704969844028, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": 0.1047, \"times_seen\": 1.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.025743526568753478, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": -0.9151, \"times_seen\": 13.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.0006006670670188765, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": -2.6483, \"times_seen\": 1.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.39072430478259307, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": -0.2114, \"times_seen\": 10.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": -0.007973901605796354, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.8933, \"times_seen\": 1.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.032412369496866815, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.7944, \"times_seen\": 11.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.0033393076245249818, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.6835, \"times_seen\": 1.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.002500561245106661, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.6498, \"times_seen\": 1.0}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.032269035352174756, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -2.7888, \"times_seen\": 5.0}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.014896387108247717, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -1.3255, \"times_seen\": 19.0}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.009073764614942918, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -0.208, \"times_seen\": 58.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.003333936238023041, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.001620709526514808, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -1.6065, \"times_seen\": 1.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.6417341622504049, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.2149, \"times_seen\": 3.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.01792776449106933, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -0.631, \"times_seen\": 5.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.018792150090718295, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.7388, \"times_seen\": 6.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.006614060630558799, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -1.4861, \"times_seen\": 3.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.014695843589432244, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.4918, \"times_seen\": 4.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.0068296385462458245, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.2607, \"times_seen\": 6.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.06564972948335494, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.2622, \"times_seen\": 56.0}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.052687944492660906, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -2.3616, \"times_seen\": 2.0}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.022220740930515372, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -0.2806, \"times_seen\": 21.0}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.7553109101033, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -1.0209, \"times_seen\": 30.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.015193829336065879, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -0.1829, \"times_seen\": 46.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.004775543987915665, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.0557, \"times_seen\": 36.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.009475308898435486, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.0046, \"times_seen\": 72.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": 0.03398236986181786, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.2948, \"times_seen\": 9.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.03896484901731347, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -0.4375, \"times_seen\": 6.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.04165542724013356, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.1768, \"times_seen\": 38.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"-\", \"escape\": -0.002850963857077666, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.3023, \"times_seen\": 1.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.0945413940336858, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": -0.1562, \"times_seen\": 26.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.02538238869327667, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.1508, \"times_seen\": 34.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.0023187726024844627, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.0301, \"times_seen\": 16.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.3657952725731717, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.2261, \"times_seen\": 10.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.007938095637716233, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": -0.4989, \"times_seen\": 1.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.3726941772982565, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.1098, \"times_seen\": 20.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.003491759603175335, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": -0.1647, \"times_seen\": 1.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"A\", \"escape\": -0.11390682161613462, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0194, \"times_seen\": 59.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"C\", \"escape\": 0.035404248436199034, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.3555, \"times_seen\": 12.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"D\", \"escape\": -0.025076943209795702, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0551, \"times_seen\": 21.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.018300362693747213, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0269, \"times_seen\": 60.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"F\", \"escape\": -0.0012399393882035876, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0515, \"times_seen\": 12.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"G\", \"escape\": 0.0011039086643150932, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0279, \"times_seen\": 73.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.019330054741207466, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0435, \"times_seen\": 82.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"I\", \"escape\": 0.01977997074775492, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.4132, \"times_seen\": 18.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.05573905828609389, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0347, \"times_seen\": 87.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.022297431998892406, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.115, \"times_seen\": 161.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"M\", \"escape\": -0.40124807337549034, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.1552, \"times_seen\": 40.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": 0.008287671120672092, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.1295, \"times_seen\": 22.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.06282986478240545, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0622, \"times_seen\": 109.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -2.5727039599566206, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0838, \"times_seen\": 184.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": -0.4426944558655232, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0616, \"times_seen\": 72.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": 0.2342058684577402, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0604, \"times_seen\": 50.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"V\", \"escape\": 0.20513943383829938, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.2324, \"times_seen\": 52.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"W\", \"escape\": -0.03003899338686923, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.1285, \"times_seen\": 28.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"Y\", \"escape\": -0.025856721241399497, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.2683, \"times_seen\": 19.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.01796512272879413, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -2.6388, \"times_seen\": 5.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.012232243811606335, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.1094, \"times_seen\": 54.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": 0.0005596540558185357, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.4261, \"times_seen\": 11.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": 0.00896541427440113, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.028, \"times_seen\": 23.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.03925370726384921, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0433, \"times_seen\": 13.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.6804648722539863, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0114, \"times_seen\": 24.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.025715103212239437, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.1251, \"times_seen\": 33.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": 0.0011978511072936238, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0667, \"times_seen\": 17.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.0002775550218414326, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.065, \"times_seen\": 54.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.014976067749750938, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0199, \"times_seen\": 19.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.0357370110012914, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.1588, \"times_seen\": 37.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": -0.008163670141417664, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.1123, \"times_seen\": 15.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.012638264873248073, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0573, \"times_seen\": 30.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.4271821417511824, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.082, \"times_seen\": 49.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": 0.0720696564452983, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.084, \"times_seen\": 12.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.016331611156641095, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0321, \"times_seen\": 28.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.03884587965950116, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0164, \"times_seen\": 81.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.028163196821087765, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0736, \"times_seen\": 34.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": -0.0014987713522896602, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0339, \"times_seen\": 1.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.014319523680949686, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.1426, \"times_seen\": 15.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.006261037802927776, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -2.6582, \"times_seen\": 2.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": 0.01577524733609138, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": -0.035244189283817735, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0013, \"times_seen\": 41.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": 0.0013950878190305109, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.348, \"times_seen\": 11.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": 0.013268711218786264, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0777, \"times_seen\": 25.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.10732136208856209, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1234, \"times_seen\": 61.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": -0.011537474279438981, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.031, \"times_seen\": 11.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": 0.005576973937277594, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1033, \"times_seen\": 53.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.3888744221076289, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1203, \"times_seen\": 19.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.11452369266502666, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.02846162967020682, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0434, \"times_seen\": 64.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.0050313735344645815, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1142, \"times_seen\": 48.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.17054157200324635, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0945, \"times_seen\": 45.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": -0.1842046518262404, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1529, \"times_seen\": 54.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.19699661650963912, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.2082, \"times_seen\": 41.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.2715056922364599, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.0367, \"times_seen\": 104.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": 0.017292278988656123, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0645, \"times_seen\": 92.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.30185008203032265, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0274, \"times_seen\": 77.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.027447206847245987, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0752, \"times_seen\": 50.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": 0.00866609466203842, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.1011, \"times_seen\": 23.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": 0.7236403539488175, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.0373, \"times_seen\": 36.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": -0.013487655151768623, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -2.5024, \"times_seen\": 7.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": 0.016079179713076933, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.026842457434760394, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.05, \"times_seen\": 13.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0029198972169187337, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.1612, \"times_seen\": 2.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.009839607792867472, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.1095, \"times_seen\": 36.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.020261141140822565, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.1538, \"times_seen\": 3.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 1.2920429201976393, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.2677, \"times_seen\": 13.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.002893883592141139, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.0077, \"times_seen\": 1.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.02702856085896146, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0832, \"times_seen\": 12.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.05472526190439029, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0819, \"times_seen\": 17.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.23076237316705178, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0276, \"times_seen\": 16.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.03659546598642331, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.0732, \"times_seen\": 10.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.04605823109162057, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.19, \"times_seen\": 8.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.007760393689259957, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0183, \"times_seen\": 4.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"A\", \"escape\": -0.8184657899900258, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0278, \"times_seen\": 33.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"C\", \"escape\": 0.11927616139039415, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.056, \"times_seen\": 45.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": 1.045403104951549, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.2697, \"times_seen\": 49.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"E\", \"escape\": -0.03669648328145798, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.0991, \"times_seen\": 16.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"F\", \"escape\": 1.1058466613302118, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0028, \"times_seen\": 26.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"G\", \"escape\": -0.025004389900618106, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.1376, \"times_seen\": 34.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"I\", \"escape\": -0.2131202074135381, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.0187, \"times_seen\": 20.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"K\", \"escape\": 0.04285482448619728, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.062, \"times_seen\": 21.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": 0.048739361117516894, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0037, \"times_seen\": 114.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"M\", \"escape\": -0.03279900154746894, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.008, \"times_seen\": 17.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": 0.34886242997270017, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0425, \"times_seen\": 42.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": -0.004615796081662444, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.1077, \"times_seen\": 60.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": -0.029210953880817972, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0064, \"times_seen\": 41.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": 0.2015563421738062, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.1568, \"times_seen\": 91.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": 0.03369280479592897, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0007, \"times_seen\": 119.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"T\", \"escape\": 0.018258274327009546, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0108, \"times_seen\": 58.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"V\", \"escape\": -0.13442202867755973, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0938, \"times_seen\": 29.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"W\", \"escape\": 0.049129927328688316, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.1172, \"times_seen\": 13.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": 0.00344550116697391, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0357, \"times_seen\": 85.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"*\", \"escape\": 0.0009288329584859731, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -2.9417, \"times_seen\": 2.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.6216929995418595, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.3557, \"times_seen\": 72.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": 0.007477464322404975, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.05086964480725835, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.2684, \"times_seen\": 15.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": 1.5397796498530198, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.3728, \"times_seen\": 25.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.035739077592089344, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.397, \"times_seen\": 7.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": -0.04626189172982351, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.2007, \"times_seen\": 13.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.5530962882556874, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.0544, \"times_seen\": 6.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": 0.005715912675744932, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": 0.8093962756722952, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.3201, \"times_seen\": 97.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.0891333423076565, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.1477, \"times_seen\": 20.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.013937439698417022, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0466, \"times_seen\": 13.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.009458740285948283, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0351, \"times_seen\": 5.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.016859298806467346, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0149, \"times_seen\": 5.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": 0.0400992484631044, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0824, \"times_seen\": 17.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.00391428282455566, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.2031, \"times_seen\": 6.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": 0.45406014966508484, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0267, \"times_seen\": 50.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"Y\", \"escape\": 0.003794127090732554, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0464, \"times_seen\": 1.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.01800754786693206, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.2704, \"times_seen\": 8.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.00470025153236118, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0403, \"times_seen\": 2.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.005319964756193288, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": -0.022, \"times_seen\": 17.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.01158490535888177, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0168, \"times_seen\": 60.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.02872307788564345, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0507, \"times_seen\": 14.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.03264219063901418, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.4033, \"times_seen\": 35.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 1.0176711098253977, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.4203, \"times_seen\": 24.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.0443176367837367, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.1163, \"times_seen\": 6.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.021007377238722983, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.3921, \"times_seen\": 7.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": 0.0208660405420477, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": -0.1572, \"times_seen\": 3.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.016606244317890314, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.1162, \"times_seen\": 1.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.022771293752940843, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": -0.2995, \"times_seen\": 2.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.001311704274854391, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.0832, \"times_seen\": 2.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.014115633413833106, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.355, \"times_seen\": 11.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.018396835534829487, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.4224, \"times_seen\": 13.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.0020596355528195113, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.1903, \"times_seen\": 5.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.002799610843235943, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.0474, \"times_seen\": 3.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.011433406815847516, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": -0.0649, \"times_seen\": 6.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.025860270233461092, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.397, \"times_seen\": 2.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.0035710193424290343, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.1546, \"times_seen\": 6.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0011478394502954055, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.0484, \"times_seen\": 10.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.005078106448586819, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.07839954424176859, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.1331, \"times_seen\": 24.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.00783737858252263, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": -0.1648, \"times_seen\": 11.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.017581172466971745, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.0449, \"times_seen\": 19.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.11784085416851556, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.2151, \"times_seen\": 18.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.043965597884968025, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.1009, \"times_seen\": 28.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 1.3643684316998441, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.2832, \"times_seen\": 13.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.012167942520007574, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.4225, \"times_seen\": 6.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.027337167335158435, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0176, \"times_seen\": 37.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.019374461432985643, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.1275, \"times_seen\": 8.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.004542740147012655, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.5499, \"times_seen\": 1.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.007130995288071181, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.154, \"times_seen\": 1.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -1.6353213736616123, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.064, \"times_seen\": 14.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.016397972133702105, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.099, \"times_seen\": 7.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": 0.004769832603700628, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0169, \"times_seen\": 4.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.052333403803759365, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0709, \"times_seen\": 20.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": -0.013243384064460358, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.2707, \"times_seen\": 7.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 0.006584132436160842, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0171, \"times_seen\": 26.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.016998407245056156, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.0361, \"times_seen\": 74.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -1.3930261010169078, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.0197, \"times_seen\": 65.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.0006612299811923864, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0917, \"times_seen\": 90.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": 0.02364901015756537, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.1542, \"times_seen\": 7.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.014453991817533351, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.2307, \"times_seen\": 9.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.006640578581759446, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -0.3588, \"times_seen\": 3.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.020853992573557363, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0158, \"times_seen\": 9.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.013168004811547422, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -0.1987, \"times_seen\": 20.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0333830946630512, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0178, \"times_seen\": 46.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.5108160402909138, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0532, \"times_seen\": 40.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.00463018816769464, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.2043, \"times_seen\": 4.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.0007875371634827736, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.011082812727734809, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.2871, \"times_seen\": 23.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.005648991355414223, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -0.3511, \"times_seen\": 34.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.008086956851651651, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -0.041, \"times_seen\": 5.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.028547313026748424, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.0963, \"times_seen\": 29.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": 0.017125686025579748, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.155, \"times_seen\": 4.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.0021432884153522484, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -2.8604, \"times_seen\": 1.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.0242921899824845, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.1149, \"times_seen\": 9.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0013562365262575345, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.0782, \"times_seen\": 1.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.20724263727358877, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.8101, \"times_seen\": 8.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.08661348515632407, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.682, \"times_seen\": 35.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.018096494023870452, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.1487, \"times_seen\": 6.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.006460365979060772, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.0558, \"times_seen\": 4.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.05525223050937674, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.0284, \"times_seen\": 26.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.030127886072112822, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.8109, \"times_seen\": 15.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.002068047463734111, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.008735953764003403, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.0433, \"times_seen\": 8.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.049181355296566656, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.498, \"times_seen\": 25.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.0057970755847165, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -0.0477, \"times_seen\": 4.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.031076602352341703, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -0.3436, \"times_seen\": 3.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.015257315772440603, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -0.636, \"times_seen\": 6.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.008968024443420557, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -2.4933, \"times_seen\": 3.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.0004494691496948285, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -2.0274, \"times_seen\": 1.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.01157330466491699, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -1.4086, \"times_seen\": 2.0}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.0010305603985384013, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -0.3145, \"times_seen\": 6.0}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.02385739466308766, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.368, \"times_seen\": 1.0}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.02759934714774578, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -0.1459, \"times_seen\": 19.0}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.01992842242108003, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -2.0572, \"times_seen\": 14.0}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.022178411580141458, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -1.6896, \"times_seen\": 13.0}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.007058766993914402, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": 0.1418, \"times_seen\": 21.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -9.615049193565963e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.8277, \"times_seen\": 5.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.011943171221529337, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.1373, \"times_seen\": 14.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.018880894374451677, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.2243, \"times_seen\": 7.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.003406523786718924, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -1.8929, \"times_seen\": 3.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.017180984493464602, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.2672, \"times_seen\": 1.0}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -0.24322662719849458, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -0.307, \"times_seen\": 45.0}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.009359447590324038, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -0.48, \"times_seen\": 7.0}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.021202641742281262, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -2.7727, \"times_seen\": 4.0}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": 0.00728711006916164, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -1.9839, \"times_seen\": 2.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.001343592688041617, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.6287, \"times_seen\": 1.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.003829426588960136, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.3265, \"times_seen\": 1.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.03663792793825589, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.3187, \"times_seen\": 4.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.007710430304931606, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -1.1388, \"times_seen\": 3.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.007205494189449211, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.1677, \"times_seen\": 2.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.006076600309064293, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.033478025646859436, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -0.3115, \"times_seen\": 10.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.00962953326673398, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -0.5968, \"times_seen\": 3.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.013038290469946106, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -1.1541, \"times_seen\": 7.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.020671533541435885, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -2.2536, \"times_seen\": 1.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.004185418652785129, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -1.0615, \"times_seen\": 2.0}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.0022099528629485115, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.1499, \"times_seen\": 1.0}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.01085203546873129, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.9319, \"times_seen\": 11.0}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.004773060909389053, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.4878, \"times_seen\": 2.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.033557110771179365, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.3332, \"times_seen\": 18.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.029650336784015553, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.1895, \"times_seen\": 13.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.0005648957983048801, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.3037, \"times_seen\": 36.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.01955542060989407, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.6567, \"times_seen\": 6.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.15375009932395245, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.5186, \"times_seen\": 45.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.020285492018191752, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.3038, \"times_seen\": 15.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.020513033244063283, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.6607, \"times_seen\": 4.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": 0.0002902593660306143, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.269, \"times_seen\": 16.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.029349973154689086, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -2.1994, \"times_seen\": 10.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -1.3481904075293192, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.2184, \"times_seen\": 11.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.0075023971691957105, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.1154, \"times_seen\": 16.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.0902826020549602, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.2828, \"times_seen\": 43.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": -0.0037357460843355506, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.1819, \"times_seen\": 16.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 0.21019239856422336, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.0393, \"times_seen\": 51.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.662244864342098, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.1561, \"times_seen\": 71.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.04865491694783591, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.0478, \"times_seen\": 78.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -1.2627053836624031, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.3771, \"times_seen\": 68.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": 0.002079078435706956, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.306, \"times_seen\": 9.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.03237628885734876, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.6371, \"times_seen\": 6.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.011277282386072623, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -2.4326, \"times_seen\": 4.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.0019488292844648941, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -0.9622, \"times_seen\": 6.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.0250202772216112, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -0.0147, \"times_seen\": 23.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.01803190196959118, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -1.3361, \"times_seen\": 5.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.6947888727899657, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -1.9836, \"times_seen\": 23.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.14648866293272245, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -1.0118, \"times_seen\": 29.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.013089752107758966, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -0.4209, \"times_seen\": 9.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.017608343287954978, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": -1.3029, \"times_seen\": 2.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": 0.04563547394001144, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2062, \"times_seen\": 5.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.0029287264368005324, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.1572, \"times_seen\": 3.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.00042654119482177954, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2645, \"times_seen\": 8.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.02067580419394862, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2939, \"times_seen\": 13.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.01700293993045583, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2507, \"times_seen\": 31.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.053533861429465104, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.3242, \"times_seen\": 21.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.010670846082863056, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.3651, \"times_seen\": 11.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0003274769413109809, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": -0.0676, \"times_seen\": 3.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.001419602476407798, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.4966925817270171, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.3483, \"times_seen\": 21.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.03492237641090292, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": -1.5507, \"times_seen\": 15.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.005039583799223858, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.3651, \"times_seen\": 7.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.4127702457948933, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.01358836223783519, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -2.517, \"times_seen\": 2.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.015583946491809863, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -2.0341, \"times_seen\": 5.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.016568969256942775, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": 0.2691, \"times_seen\": 20.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.3707321620803384, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -0.0799, \"times_seen\": 40.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.00099389272838116, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -1.7662, \"times_seen\": 4.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.01597824599212384, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.7527, \"times_seen\": 4.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.0149175498904873, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.2316, \"times_seen\": 2.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.0836243873670584, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.007133055575421298, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.5893, \"times_seen\": 12.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.016398855212463512, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.6831, \"times_seen\": 4.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -1.1845901196296895, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -2.1539, \"times_seen\": 3.0}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.0037793304472771723, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.6432, \"times_seen\": 1.0}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.00011851271929269228, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.3384, \"times_seen\": 1.0}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.003285618214762671, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.1444, \"times_seen\": 1.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.005357272092804982, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -0.8247, \"times_seen\": 4.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.008989980438369384, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.8552, \"times_seen\": 3.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.012922766355691057, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.5027, \"times_seen\": 5.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.02395919320501477, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -0.5849, \"times_seen\": 17.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0025394983242330873, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -1.0821, \"times_seen\": 16.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.006655191100869963, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.0092, \"times_seen\": 2.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.0037915976014556776, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": 0.2883, \"times_seen\": 3.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.005223085756900615, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": 0.2955, \"times_seen\": 2.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.01004957206023764, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.7003, \"times_seen\": 4.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.014169625072018922, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.7224, \"times_seen\": 6.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.06819896464169117, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -2.0355, \"times_seen\": 13.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.008598493859723829, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -2.0548, \"times_seen\": 7.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.012946471772930233, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.5874, \"times_seen\": 14.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.0019708892130855093, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.1873, \"times_seen\": 1.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.023858139567061325, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 0.1446, \"times_seen\": 40.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.02614592704874781, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -0.4409, \"times_seen\": 16.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.00822078440844932, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -1.1788, \"times_seen\": 1.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.07731560358355612, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -0.7601, \"times_seen\": 12.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.03626825870413106, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 0.0623, \"times_seen\": 8.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": -0.012351369932452052, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -0.2966, \"times_seen\": 5.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.02336470425258108, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.6379, \"times_seen\": 7.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.0065479920799976785, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -2.7301, \"times_seen\": 1.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.05578119217626613, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -0.1169, \"times_seen\": 8.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.011314748272178533, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.7186, \"times_seen\": 2.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.0028709141706836894, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -2.5205, \"times_seen\": 1.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.041999437348990046, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.7215, \"times_seen\": 17.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.009737204216372758, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.0857, \"times_seen\": 4.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.015638154367100063, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.4944, \"times_seen\": 6.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.003883515840878754, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -1.5703, \"times_seen\": 1.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.0009723025223768182, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -2.8567, \"times_seen\": 1.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.018705141553424665, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -0.9693, \"times_seen\": 9.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.015147214400221294, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -1.6063, \"times_seen\": 26.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.054445104435233635, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -0.4359, \"times_seen\": 16.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.012248495505179842, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -0.5815, \"times_seen\": 1.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.0016608613189892367, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.866, \"times_seen\": 1.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.023658090471727483, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -0.2114, \"times_seen\": 6.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.017933795891867433, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.0541, \"times_seen\": 10.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.002844292515365079, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.1178, \"times_seen\": 11.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.008320732063123169, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.4829, \"times_seen\": 2.0}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.0031062236727790018, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -2.012, \"times_seen\": 1.0}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.002637565276772036, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -2.5336, \"times_seen\": 1.0}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.022928028471593996, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": 0.4407, \"times_seen\": 11.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.00363849074455924, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.8988, \"times_seen\": 2.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.002997562685280583, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.9818, \"times_seen\": 1.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.008540643589857322, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.0135, \"times_seen\": 10.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.001834723227927041, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.5409, \"times_seen\": 1.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.0032570701813625378, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.3536, \"times_seen\": 42.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.061463212220120314, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.1522, \"times_seen\": 28.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.006370391719941681, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.9938, \"times_seen\": 2.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.0189473614270326, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.7254, \"times_seen\": 7.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.0052820222357738466, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.8224, \"times_seen\": 9.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": -0.026940341263265118, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.142, \"times_seen\": 27.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.060157875003050885, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.9137, \"times_seen\": 22.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.04226837644292959, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.3512, \"times_seen\": 32.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.029758010571028823, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.6421, \"times_seen\": 12.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.053574624205497745, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": 0.1647, \"times_seen\": 50.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": -0.019404035447337445, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": 0.1258, \"times_seen\": 8.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.020898278604084154, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.3337, \"times_seen\": 16.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.010630593936785313, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.6193, \"times_seen\": 2.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.01711886708406215, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.5219, \"times_seen\": 19.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.001782807335788788, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.2702, \"times_seen\": 54.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.3187986123758025, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.3731, \"times_seen\": 75.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": 0.060437768014299405, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.65, \"times_seen\": 12.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.008526354106802468, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.5844, \"times_seen\": 3.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.0022941742280254297, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.766, \"times_seen\": 3.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.009262635206227863, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.3437, \"times_seen\": 4.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.012257270710658253, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.098, \"times_seen\": 7.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.010870624172508371, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.5413, \"times_seen\": 6.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.029162475044461265, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -1.7257, \"times_seen\": 18.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.005250935901899738, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -1.0141, \"times_seen\": 7.0}, {\"site\": 715, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.015673279706309617, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -2.6831, \"times_seen\": 1.0}, {\"site\": 715, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.005212687574488368, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -2.4214, \"times_seen\": 1.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.0027706710610250446, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -2.2291, \"times_seen\": 2.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.031142443576309676, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -2.5731, \"times_seen\": 9.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.0258188360530868, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -1.5682, \"times_seen\": 12.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.06419076433113706, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -0.1762, \"times_seen\": 47.0}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.00022582216267718873, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.3054, \"times_seen\": 1.0}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0027467810747779276, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.6882, \"times_seen\": 1.0}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.029874059042682442, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.9977, \"times_seen\": 5.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.007167873611800005, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -1.3676, \"times_seen\": 4.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.005587425951086784, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.8207, \"times_seen\": 2.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.0034880293009421364, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -2.3019, \"times_seen\": 1.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.006326383538073135, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -2.8793, \"times_seen\": 2.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.007928941811656072, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.0029069903582439457, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -1.6519, \"times_seen\": 3.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0017127377281720385, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -1.1452, \"times_seen\": 1.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.0021274459070532094, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -2.3651, \"times_seen\": 1.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.7273261459931207, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -0.1681, \"times_seen\": 7.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.0030001262249966876, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -1.12, \"times_seen\": 1.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.010688808447406455, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -0.9729, \"times_seen\": 5.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.024703150755660066, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": 0.1971, \"times_seen\": 5.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.045856141575212686, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -0.552, \"times_seen\": 21.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.003693085562226902, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": 0.3561, \"times_seen\": 4.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.003764730784260121, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -1.8336, \"times_seen\": 1.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.004925388870744635, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -0.1125, \"times_seen\": 2.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.003928235926124416, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -1.4441, \"times_seen\": 1.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.017229628499628207, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.11758851034966272, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.3543, \"times_seen\": 22.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.006713648431444132, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": 0.106, \"times_seen\": 2.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.00025695524178261054, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.394, \"times_seen\": 1.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.00027135351576138255, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.3071, \"times_seen\": 16.0}, {\"site\": 722, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.017786313515433208, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": 0.0546, \"times_seen\": 4.0}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": 0.003933752197894804, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.3488577129306346, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": 0.3018, \"times_seen\": 8.0}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.008687506914251858, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": -0.9196, \"times_seen\": 4.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.021740273384967337, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": 0.0311, \"times_seen\": 4.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.015496015932416974, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -0.4216, \"times_seen\": 5.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.004831814394980855, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -2.1136, \"times_seen\": 2.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.04991421424531068, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -1.2101, \"times_seen\": 4.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.0009650452622458251, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -0.4228, \"times_seen\": 1.0}, {\"site\": 725, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.022697062129510514, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -2.5579, \"times_seen\": 2.0}, {\"site\": 725, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.009798949572176793, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -1.3273, \"times_seen\": 19.0}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.011416460343048124, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": 0.3624, \"times_seen\": 1.0}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.011516915891963332, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.8092, \"times_seen\": 1.0}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.41931756999813985, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.6593, \"times_seen\": 4.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.002615634320964233, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.3591, \"times_seen\": 1.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.02345683025251218, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.2728, \"times_seen\": 20.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.0009278265927393518, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -3.0775, \"times_seen\": 2.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.017870700704380144, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.6208, \"times_seen\": 2.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.0006491545741404027, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.1699, \"times_seen\": 3.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.0035641474723202334, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -1.1008, \"times_seen\": 1.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.005866910620922579, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.5495, \"times_seen\": 2.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -0.2119818970131542, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -1.1321, \"times_seen\": 36.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": 0.7448277061319325, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": 0.0016380164465921074, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -2.2466, \"times_seen\": 5.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": 0.012801802733167321, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -1.9343, \"times_seen\": 7.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.012872821383684315, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.2513, \"times_seen\": 37.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.10934992393411824, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.2091, \"times_seen\": 44.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.01252725000449179, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.04723461590983734, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.2056, \"times_seen\": 32.0}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.003290645578958593, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -2.8693, \"times_seen\": 1.0}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.006770384088429946, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -2.9305, \"times_seen\": 1.0}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.12872805047926092, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -0.7708, \"times_seen\": 18.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.03511634599831221, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -0.4737, \"times_seen\": 13.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.011789437277307545, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -0.9347, \"times_seen\": 4.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.014083882705082278, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": 0.2248, \"times_seen\": 32.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.0076320063836232315, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -2.7603, \"times_seen\": 2.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.00553897382133464, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -1.162, \"times_seen\": 1.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.07227080719367246, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.0825, \"times_seen\": 28.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.020736628219936916, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.7428, \"times_seen\": 6.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.006547402555981767, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -1.1909, \"times_seen\": 3.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.13370147960428827, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -1.0983, \"times_seen\": 20.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.008346598031685587, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.2029, \"times_seen\": 5.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.009909868666969806, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.4477, \"times_seen\": 3.0}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.015880764615301253, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -0.0938, \"times_seen\": 9.0}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.004849551132403589, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -1.4082, \"times_seen\": 4.0}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.005203760378787879, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -1.4028, \"times_seen\": 4.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.02233558862977651, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.017, \"times_seen\": 20.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.012623875085408413, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.6831, \"times_seen\": 5.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.0005311144121451045, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.036, \"times_seen\": 1.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.018379045918997305, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -2.4426, \"times_seen\": 5.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.07486303417673355, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.5423, \"times_seen\": 4.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.01283418116449696, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.4984, \"times_seen\": 5.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.003015872181899636, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -0.4777, \"times_seen\": 7.0}, {\"site\": 735, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.0035526088781220352, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.5456, \"times_seen\": 4.0}, {\"site\": 735, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.01448564639086451, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.4725, \"times_seen\": 4.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.011580876343373995, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": 0.0824, \"times_seen\": 6.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.16080217779615585, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.1671, \"times_seen\": 39.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.004750839914163609, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.4855, \"times_seen\": 1.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.009028115954855951, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.0817, \"times_seen\": 3.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.004374593609045806, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.0087, \"times_seen\": 5.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"F\", \"escape\": 0.0013225332021010946, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.2664, \"times_seen\": 3.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": 0.035814306537840034, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.4403, \"times_seen\": 25.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"K\", \"escape\": -0.0027387838071144767, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.0781, \"times_seen\": 4.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.0254829551087952, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.9326, \"times_seen\": 6.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"S\", \"escape\": -0.8277360886681311, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.3955, \"times_seen\": 2.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.0002274679365235596, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.0225, \"times_seen\": 6.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": -0.01948262799822527, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.2248, \"times_seen\": 8.0}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.007900437694888652, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.7764, \"times_seen\": 2.0}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.0024219209857577217, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.4574, \"times_seen\": 1.0}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"V\", \"escape\": 0.009841488136356264, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.8876, \"times_seen\": 4.0}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.8350335647155847, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -0.1766, \"times_seen\": 6.0}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.02601927293342948, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": 0.1886, \"times_seen\": 6.0}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.020666944678720253, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -2.1587, \"times_seen\": 1.0}, {\"site\": 740, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.014574062539174997, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -2.6612, \"times_seen\": 4.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.07898483831570649, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -1.9342, \"times_seen\": 3.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.018272181161086164, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -0.6324, \"times_seen\": 12.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": -0.03039758536729401, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -0.8634, \"times_seen\": 10.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.025036467543438336, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -1.8853, \"times_seen\": 8.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.0038266628716757344, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -0.4687, \"times_seen\": 1.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.008182787291581506, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -2.1101, \"times_seen\": 2.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.009893237672148484, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -0.381, \"times_seen\": 4.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.025980884144014553, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -1.2556, \"times_seen\": 9.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.012014204472524243, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -0.5194, \"times_seen\": 11.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.0028769515423491816, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -2.9882, \"times_seen\": 1.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.010908345475429659, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -0.4782, \"times_seen\": 4.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.005668325928776143, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": 0.0849, \"times_seen\": 2.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.022413558449193134, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -2.1692, \"times_seen\": 3.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.03264970711397383, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -0.953, \"times_seen\": 10.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.1817979486523238, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -0.334, \"times_seen\": 31.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.002841649106202101, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -2.1849, \"times_seen\": 1.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.002694928125455011, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -0.7858, \"times_seen\": 1.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.011966776200586308, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.3931, \"times_seen\": 11.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.7857816418934572, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.2878, \"times_seen\": 22.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.0019988954269288556, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.1667, \"times_seen\": 2.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.0008701649457088225, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.1635, \"times_seen\": 3.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.010550729517778985, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.0825, \"times_seen\": 4.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.01355924501315871, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.010210877547728706, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.047, \"times_seen\": 4.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.05030296983282194, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.1863, \"times_seen\": 8.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 1.2540504719506302, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.4162, \"times_seen\": 12.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.07256603171222589, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.5398, \"times_seen\": 13.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": 0.004971014251874866, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.8477, \"times_seen\": 5.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.01686564102778914, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.5605, \"times_seen\": 11.0}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.001883249551435846, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.2959, \"times_seen\": 1.0}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.00042775743275398626, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.1098, \"times_seen\": 1.0}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": 0.013105353668670957, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.3491, \"times_seen\": 5.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.009501253746816696, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -1.0003, \"times_seen\": 13.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.04772284496736801, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": 0.2269, \"times_seen\": 79.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.057865173754357624, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.3044, \"times_seen\": 16.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.02533490345606117, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.0421, \"times_seen\": 31.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.026901458543611447, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.1217, \"times_seen\": 13.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.005624460130165589, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": 0.0836, \"times_seen\": 20.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.02066818067221235, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.0658, \"times_seen\": 14.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.26832869607089027, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0264, \"times_seen\": 44.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": 0.022183599021611145, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": -0.0541, \"times_seen\": 2.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.02347121747162365, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": -0.2394, \"times_seen\": 5.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.02627796995878608, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.2424, \"times_seen\": 9.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.006173044883061997, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0683, \"times_seen\": 7.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.01117325442597477, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0901, \"times_seen\": 9.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.026484285562102704, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0153, \"times_seen\": 5.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.013913676392128755, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -2.0375, \"times_seen\": 6.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.008492214077349316, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -1.0664, \"times_seen\": 3.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.0034120203884224674, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.0729, \"times_seen\": 12.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.49719334909298124, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -2.6643, \"times_seen\": 10.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.009559143042518804, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.3644, \"times_seen\": 2.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.010813672327007773, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.776, \"times_seen\": 6.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.018228327774452695, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.7661, \"times_seen\": 6.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.016864632274546983, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.673, \"times_seen\": 2.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.02253824406254168, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -2.7073, \"times_seen\": 2.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0088019728038624, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.018412661395011205, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.3226, \"times_seen\": 12.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.0034794263041938575, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -0.4671, \"times_seen\": 1.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.02827416638331407, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.0366, \"times_seen\": 76.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.007665745041879458, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -2.891, \"times_seen\": 4.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.059519663513423055, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -0.0719, \"times_seen\": 24.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.013869244044526536, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.1158, \"times_seen\": 12.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.008851952381590037, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.0848, \"times_seen\": 5.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.020881235856298065, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.1702, \"times_seen\": 8.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"A\", \"escape\": -0.009332391329147626, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.2403, \"times_seen\": 2.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.006851019951702409, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -1.4802, \"times_seen\": 3.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": 0.019971340137847095, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -1.0858, \"times_seen\": 5.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.003263544257682151, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -2.2523, \"times_seen\": 1.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"A\", \"escape\": -0.008051755619302305, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.943, \"times_seen\": 2.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.010202266939247225, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -2.4891, \"times_seen\": 6.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.003907451724139333, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"M\", \"escape\": -0.002262043511226923, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -2.9344, \"times_seen\": 1.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.0343376284719732, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.7854, \"times_seen\": 7.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.007486345449989045, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -2.8243, \"times_seen\": 1.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.3861768376278336, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.0894, \"times_seen\": 58.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -0.0028399092718896088, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.9744, \"times_seen\": 7.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.007038925715127503, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.7512, \"times_seen\": 5.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.002747752351331141, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -0.6318, \"times_seen\": 4.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": 0.021754317552215942, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -2.4308, \"times_seen\": 7.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.01683925571811188, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.2737, \"times_seen\": 11.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.05522127267623622, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.0587, \"times_seen\": 5.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.012035468778223321, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.3216, \"times_seen\": 5.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.008928150319987489, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.1119, \"times_seen\": 7.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.03200407957296496, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.4627, \"times_seen\": 3.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.008011870762756956, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 1.0639899631439105, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.1522, \"times_seen\": 15.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.014248436505656468, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.0004, \"times_seen\": 9.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.0006721333833199356, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.2785, \"times_seen\": 1.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.0034288054110497386, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.9521, \"times_seen\": 1.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.015908343028714998, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.2458, \"times_seen\": 7.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.0077266648358053835, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.2885, \"times_seen\": 9.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.0701894997861304, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.2136, \"times_seen\": 15.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.006254633392680021, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.5576, \"times_seen\": 2.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.006831161480023774, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -0.2353, \"times_seen\": 2.0}, {\"site\": 757, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.004558117570750992, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -1.2855, \"times_seen\": 1.0}, {\"site\": 757, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.03461583579857594, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -1.6236, \"times_seen\": 5.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.7758158135987465, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.1197, \"times_seen\": 47.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.012297539739682116, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -1.0763, \"times_seen\": 5.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": 0.00764406894386521, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.14153869123942014, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.1772, \"times_seen\": 71.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.048262307688491594, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.2376, \"times_seen\": 9.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.029996721079515006, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.1582, \"times_seen\": 6.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.018287279926079987, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.1127, \"times_seen\": 10.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.004545351794966567, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.0003, \"times_seen\": 5.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": 0.005000030381995582, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.115, \"times_seen\": 15.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.007740043121594025, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -0.3831, \"times_seen\": 7.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.02008553179385049, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -1.9731, \"times_seen\": 7.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.010403064092003195, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -1.1412, \"times_seen\": 3.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": 0.03460263123977469, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": 0.3165, \"times_seen\": 10.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": -0.009087386857244683, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -0.0864, \"times_seen\": 5.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.017243177686139942, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -1.6237, \"times_seen\": 8.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.0013192776514580726, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -0.6558, \"times_seen\": 1.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0012916429191056125, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -0.0134, \"times_seen\": 9.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.003591854945333564, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": 0.16, \"times_seen\": 7.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.003120717073554403, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -0.4704, \"times_seen\": 1.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.016552701636335345, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -1.5481, \"times_seen\": 1.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": 0.4773476005734348, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.226, \"times_seen\": 37.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": -0.032362633884723505, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.6222, \"times_seen\": 14.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": -0.023353764393602105, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.3145, \"times_seen\": 12.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.007662382536596657, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.8716, \"times_seen\": 17.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": -0.015843694703450012, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.4497, \"times_seen\": 5.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.05440405387522505, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.2276, \"times_seen\": 38.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.022859172068523104, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.085, \"times_seen\": 12.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.01500646833921132, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.4162, \"times_seen\": 5.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.19560823122986087, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.7349, \"times_seen\": 32.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.022074957302492926, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.265, \"times_seen\": 20.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.007399310896810047, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.6305, \"times_seen\": 35.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 0.0017584412681152196, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -2.9308, \"times_seen\": 6.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.04543420929188539, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": 0.3452, \"times_seen\": 23.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.05485441368333621, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": 0.1124, \"times_seen\": 69.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -1.1581620493505997, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.3048, \"times_seen\": 47.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.06210206941530856, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.0973, \"times_seen\": 35.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.0026670819652142986, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.3854, \"times_seen\": 22.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": -0.013500448430549912, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.8069, \"times_seen\": 11.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": 0.005792293121816643, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.3796, \"times_seen\": 12.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": -0.012620457349977021, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -2.5877, \"times_seen\": 4.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.011872145762493597, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -1.5482, \"times_seen\": 4.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.5883677715885431, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.2881, \"times_seen\": 27.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": 0.5642218690074288, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.9356, \"times_seen\": 4.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.0029294048318618316, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.0548, \"times_seen\": 9.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": 0.011538280512052409, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.5001, \"times_seen\": 12.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.4432410792623456, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.2185, \"times_seen\": 1.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.009391912100268567, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.495, \"times_seen\": 19.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"V\", \"escape\": 0.03792673143957163, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.7384, \"times_seen\": 6.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.00205568759536643, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.9641, \"times_seen\": 1.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"-\", \"escape\": -0.0013157283909018215, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.007874369354999012, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.9905, \"times_seen\": 2.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.013271343291014377, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -1.6376, \"times_seen\": 8.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.012434867616136751, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.6086, \"times_seen\": 3.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.0038104628881955056, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -1.5951, \"times_seen\": 1.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.008294135555594391, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.3293, \"times_seen\": 1.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.004678168929698714, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": 0.2056, \"times_seen\": 2.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.10135053380814456, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.0657, \"times_seen\": 18.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.013129630462887176, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.633, \"times_seen\": 11.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": -0.0031290762608137956, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.006591855486809779, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -0.3954, \"times_seen\": 6.0}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0029541090833522686, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -1.116, \"times_seen\": 1.0}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.006263383959467297, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -2.3797, \"times_seen\": 2.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.008264386717048225, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.8115, \"times_seen\": 11.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.9417783625447392, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.0015635033201743863, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.697, \"times_seen\": 11.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.4996407324680811, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.4963, \"times_seen\": 43.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.03037938578000261, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -1.1789, \"times_seen\": 8.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.016573970942131474, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": 0.1124, \"times_seen\": 70.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.02404810447942234, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.4113, \"times_seen\": 7.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.05763137434474721, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.3442, \"times_seen\": 112.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.8487968848251005, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.7485, \"times_seen\": 108.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.14830666391278036, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2311, \"times_seen\": 125.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.01811671081649146, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.1186, \"times_seen\": 55.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": 0.195178226750293, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.4384, \"times_seen\": 57.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": 0.06629720939159882, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2743, \"times_seen\": 49.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": -0.0023136939234941023, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.8515, \"times_seen\": 44.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": 0.016514971740797635, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.3583, \"times_seen\": 35.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.20481852440486625, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.5519, \"times_seen\": 83.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.033132785424399576, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.1667, \"times_seen\": 23.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 0.03810505666912895, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2105, \"times_seen\": 79.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": 0.003285912317499567, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -2.7401, \"times_seen\": 12.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": -0.03800010407879365, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": 0.0564, \"times_seen\": 20.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.07966254832906759, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2939, \"times_seen\": 212.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.04632484246183951, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2042, \"times_seen\": 153.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.008749257521947839, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.6609, \"times_seen\": 65.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.01003717297686138, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.8462, \"times_seen\": 148.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.01612717016954175, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.3517, \"times_seen\": 39.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"Y\", \"escape\": 0.20502332259689648, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.1698, \"times_seen\": 58.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.009385553119130627, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.5587, \"times_seen\": 3.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.009720890990301925, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.6704, \"times_seen\": 11.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.003844235895671928, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.4593, \"times_seen\": 1.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.004191260037235979, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -2.8362, \"times_seen\": 1.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.04888777058070723, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.2712, \"times_seen\": 18.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.028585123112257346, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -1.0503, \"times_seen\": 18.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.003057587492684381, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9103, \"times_seen\": 5.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.00681828222847775, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.5854, \"times_seen\": 3.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.0049561190242580315, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.4737, \"times_seen\": 1.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.0830696566439773, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -0.4717, \"times_seen\": 47.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.004878017164373132, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -3.0029, \"times_seen\": 1.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.007743736348121011, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.686, \"times_seen\": 2.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.010620538563212012, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.7146, \"times_seen\": 3.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.004754950972225769, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.8167, \"times_seen\": 1.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -1.8025191098442792, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -0.1069, \"times_seen\": 19.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.010188666758742958, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9758, \"times_seen\": 3.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": -0.00574800755164277, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.2876, \"times_seen\": 2.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.0022341333219926957, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9508, \"times_seen\": 4.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.16433388033028903, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -0.4086, \"times_seen\": 66.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.056552815196056386, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.2719, \"times_seen\": 15.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.046421854905577924, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.6338, \"times_seen\": 10.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": 0.0137993662359232, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.4901, \"times_seen\": 3.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": 0.016113028062096416, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.7602, \"times_seen\": 2.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0002246377932143502, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -1.0373, \"times_seen\": 5.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": 0.011892884604052844, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.8523, \"times_seen\": 7.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.004126596182863933, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.8312, \"times_seen\": 2.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.021000832666927205, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.7854, \"times_seen\": 5.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.0007941598863221613, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -1.3317, \"times_seen\": 5.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.018260565997675282, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.3216, \"times_seen\": 19.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.02153473863314699, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.6707, \"times_seen\": 9.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.06805869824001427, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.6794, \"times_seen\": 21.0}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.0017910827114093117, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -0.6339, \"times_seen\": 5.0}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.020446863934273418, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -1.584, \"times_seen\": 1.0}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.0015503695142449338, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -2.1972, \"times_seen\": 3.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.0026815928050264943, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -3.2328, \"times_seen\": 1.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.058959651167701556, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.8752, \"times_seen\": 2.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.0015094359225704748, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -0.3916, \"times_seen\": 1.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.01050652317612607, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.932, \"times_seen\": 2.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.006281768042519154, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.8012, \"times_seen\": 3.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.003345936530288648, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -1.7483, \"times_seen\": 2.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.0028229826035938545, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -1.6581, \"times_seen\": 1.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.010072759179767035, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.7155, \"times_seen\": 3.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.016050708443349642, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.5069, \"times_seen\": 1.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.0006429700450229272, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": -0.0735, \"times_seen\": 5.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.004541421743219964, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.017881628803878304, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": -1.9023, \"times_seen\": 3.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.013896375876682217, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.3042, \"times_seen\": 9.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.006985931548947793, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.1008, \"times_seen\": 22.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.006964045074787292, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.2622, \"times_seen\": 2.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.014070284885504297, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -1.6319, \"times_seen\": 2.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.012056970215118964, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -1.7783, \"times_seen\": 4.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.003300691463996707, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -2.3639, \"times_seen\": 1.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.008929522669156073, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -1.8787, \"times_seen\": 5.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.0009473207774026466, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -2.8274, \"times_seen\": 1.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.037092224354643315, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -0.946, \"times_seen\": 13.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": 0.02370176808367297, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -2.3628, \"times_seen\": 2.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.013370570599384127, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -0.4753, \"times_seen\": 40.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.00949161165027678, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -1.1689, \"times_seen\": 12.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.015059686264862255, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -2.5316, \"times_seen\": 2.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.013176151464418783, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -0.8224, \"times_seen\": 4.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -1.3364629988520416, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": 0.3651, \"times_seen\": 14.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.0007422554354490611, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -0.3563, \"times_seen\": 11.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.00511581286913504, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -0.2552, \"times_seen\": 27.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.8435360161967617, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": 0.0398, \"times_seen\": 17.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.012492109853256562, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -0.0258, \"times_seen\": 15.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.01516921374837847, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -1.8032, \"times_seen\": 1.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.00030673369258458696, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.0559, \"times_seen\": 3.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.050311198650222114, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.2593, \"times_seen\": 26.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.009301465580478747, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.1689, \"times_seen\": 14.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.003874731007082953, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.0755, \"times_seen\": 21.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.07543079930896007, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.0878, \"times_seen\": 10.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": -0.012907136457107896, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.192, \"times_seen\": 10.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.011209167946942468, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.4499, \"times_seen\": 6.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.0026254095678799154, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -3.0345, \"times_seen\": 1.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.008060066919062905, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.1213, \"times_seen\": 1.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.018261146498506405, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.5907, \"times_seen\": 1.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.027114742198236168, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.2896, \"times_seen\": 9.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.005837969330911102, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.2113, \"times_seen\": 2.0}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": 0.014533733218260524, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.2009, \"times_seen\": 3.0}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.0038361029275538953, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.3996, \"times_seen\": 2.0}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.021262620333291304, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -0.2612, \"times_seen\": 8.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.013157125932302402, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -1.3972, \"times_seen\": 3.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.01145309247017223, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -1.0212, \"times_seen\": 2.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.004156798902174625, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.1269, \"times_seen\": 1.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.031780387146665263, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.1099, \"times_seen\": 14.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.003936481361895389, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.5215, \"times_seen\": 1.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.018424580301311708, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.5208, \"times_seen\": 6.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.004172561298904338, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.8397, \"times_seen\": 1.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.043592315145869795, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.7879, \"times_seen\": 22.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.08414187243069403, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -1.0432, \"times_seen\": 39.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.039530010854513, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.59, \"times_seen\": 47.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -1.7895375240362148, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.1042, \"times_seen\": 16.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.046661857988053716, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -0.2481, \"times_seen\": 11.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.2239045178828205, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.0136, \"times_seen\": 49.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.023232756379390037, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -1.9129, \"times_seen\": 5.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.06681196823505174, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.0575, \"times_seen\": 60.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": -0.021708921178944122, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -0.377, \"times_seen\": 5.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.013798119703324466, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -2.5266, \"times_seen\": 1.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.017775565246963453, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.4484, \"times_seen\": 14.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.0034430862871462544, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -1.1697, \"times_seen\": 1.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.03553707002799939, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.1905, \"times_seen\": 16.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.019794997359041493, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -1.029, \"times_seen\": 8.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.008205157700097507, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -1.0268, \"times_seen\": 8.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": 0.021289575643751606, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.767, \"times_seen\": 4.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.008225705040731779, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": 0.0321, \"times_seen\": 3.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.02085975375861389, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.2182, \"times_seen\": 9.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.006959685780997265, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.0847, \"times_seen\": 2.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.015266551683658534, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": 0.0834, \"times_seen\": 8.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.0071948528706382055, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.3067, \"times_seen\": 7.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.11188250229485744, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.1617, \"times_seen\": 51.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.008870477719526915, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.249, \"times_seen\": 36.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.007415880353840194, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.255, \"times_seen\": 16.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": 0.014541876383231702, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.6562, \"times_seen\": 8.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.9205297154356649, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.731, \"times_seen\": 1.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.018991741466553663, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -1.191, \"times_seen\": 9.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.020334782747289618, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -2.609, \"times_seen\": 4.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 1.2860680835500093, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -2.6049, \"times_seen\": 2.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.047869252031640275, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": 0.3002, \"times_seen\": 18.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.035650218798059, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -0.317, \"times_seen\": 13.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.002824984320203031, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -0.9981, \"times_seen\": 2.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.003182946270116128, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -3.162, \"times_seen\": 1.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.029055924294272333, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -1.9642, \"times_seen\": 2.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.00528896086413992, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.9036, \"times_seen\": 2.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.0304079880381602, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": 0.0132, \"times_seen\": 13.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.021785197370103124, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.782, \"times_seen\": 3.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"escape\": 0.0197625262345114, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"T\", \"escape\": -0.004477853624097987, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.8037, \"times_seen\": 3.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.006237011715155772, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.8941, \"times_seen\": 2.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.025854783410498454, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -2.1323, \"times_seen\": 13.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.0017642371358331018, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -0.6658, \"times_seen\": 2.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.001333635871951156, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -0.5911, \"times_seen\": 3.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.01773695802944681, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -1.1482, \"times_seen\": 18.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.03209790397798678, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -0.3125, \"times_seen\": 14.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.009467469294621358, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": 0.187, \"times_seen\": 16.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.04057049242423596, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": 0.0374, \"times_seen\": 8.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.018735156829878412, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": 0.064, \"times_seen\": 7.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.010486752389080188, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.09, \"times_seen\": 6.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.007854363112829655, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.0181, \"times_seen\": 25.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.021958438550371162, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.5386, \"times_seen\": 23.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.01058234586521581, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.9177, \"times_seen\": 3.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.008493427113501753, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": 0.036, \"times_seen\": 5.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.002948645500143872, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.6043, \"times_seen\": 7.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.017013161213908196, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.4385, \"times_seen\": 36.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.020528751818913817, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.2454, \"times_seen\": 4.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.1902036590942467, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.6375, \"times_seen\": 4.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.010080797220617771, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.269, \"times_seen\": 11.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.02918061173287174, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.2892, \"times_seen\": 20.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.0557974187197753, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": -0.053, \"times_seen\": 26.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"N\", \"escape\": -0.013107347431938886, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.3933, \"times_seen\": 16.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.0009935161725334214, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.2878, \"times_seen\": 9.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.00541979002042842, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.3498, \"times_seen\": 1.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.30168780567858633, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.3254, \"times_seen\": 26.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.017480697480730476, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.1526, \"times_seen\": 8.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.010811150164143536, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.31, \"times_seen\": 12.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.005614714487331397, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": -0.5619, \"times_seen\": 2.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.014784989277690211, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.2922, \"times_seen\": 3.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.011123458044377373, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.3158, \"times_seen\": 9.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.004028856030843985, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.0945, \"times_seen\": 4.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.006929308892788482, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": -0.9126, \"times_seen\": 14.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.0020149256890561844, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": -0.2489, \"times_seen\": 2.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.0017772593190081899, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.017644543221345666, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.1416, \"times_seen\": 34.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.0023269392410408935, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.4099, \"times_seen\": 23.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"A\", \"escape\": -0.05469797625609658, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.2063, \"times_seen\": 20.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.0320591168894157, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.1096, \"times_seen\": 18.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -4.490395029704803, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"E\", \"escape\": -0.024178856579426394, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.3958, \"times_seen\": 14.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.016387996824683084, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -1.3189, \"times_seen\": 15.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"G\", \"escape\": -0.1200825648324722, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.1069, \"times_seen\": 27.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.08799626841728808, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.3463, \"times_seen\": 26.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.03249839596882581, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.1034, \"times_seen\": 16.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"K\", \"escape\": -0.012832050288857602, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.3197, \"times_seen\": 3.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.05354103953886836, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.3055, \"times_seen\": 21.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"M\", \"escape\": 0.0010147404633908824, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.0388, \"times_seen\": 3.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.08626148785186814, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.4141, \"times_seen\": 44.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"escape\": -0.00998412899333377, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.2016, \"times_seen\": 4.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"R\", \"escape\": -0.0005995975908554945, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -1.0075, \"times_seen\": 13.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -1.2255840386546315, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.4444, \"times_seen\": 52.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"T\", \"escape\": -0.06361365448583932, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.0623, \"times_seen\": 20.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"V\", \"escape\": 0.0026416113636285217, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.0814, \"times_seen\": 26.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"W\", \"escape\": -0.0020365498667286146, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -1.3168, \"times_seen\": 7.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.007430132801806097, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -3.0468, \"times_seen\": 2.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.010519532078554284, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -1.1026, \"times_seen\": 6.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.0037130838455768484, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -0.7217, \"times_seen\": 2.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.01968977622183563, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.10180543997416788, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -1.0526, \"times_seen\": 4.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.04041652966351426, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -1.2891, \"times_seen\": 2.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.00462390627469945, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -0.3219, \"times_seen\": 2.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.0006077157247330241, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": 0.0924, \"times_seen\": 3.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.010787442322227173, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -1.6839, \"times_seen\": 2.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.010184593190674749, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0033643888270371096, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.011675302540014552, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -0.3295, \"times_seen\": 4.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.04612714169761836, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -0.3617, \"times_seen\": 10.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.0191633644123106, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -0.7709, \"times_seen\": 3.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.02091347802574789, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -2.0614, \"times_seen\": 6.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.005891717941764521, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -2.0504, \"times_seen\": 9.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.004416245482166549, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -2.6231, \"times_seen\": 2.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.005781648444561696, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -3.0068, \"times_seen\": 2.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.002235553353220964, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -1.0263, \"times_seen\": 1.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.03300702005120774, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.5187, \"times_seen\": 2.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.007783964596272456, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.5735, \"times_seen\": 4.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.001924355921228315, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.3392, \"times_seen\": 1.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.0027618842488614428, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.9684, \"times_seen\": 1.0}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.020900098177942448, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": 0.1322, \"times_seen\": 18.0}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.008494051090893101, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -2.2033, \"times_seen\": 1.0}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.006423639218174865, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 799, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.01013443806279842, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -2.1336, \"times_seen\": 3.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.001210197014304619, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.9067, \"times_seen\": 2.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.010204644578894036, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -2.2039, \"times_seen\": 4.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.011161525865411479, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.764, \"times_seen\": 3.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.01133729906920688, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.5422, \"times_seen\": 7.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.0021950059236769248, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -1.4122, \"times_seen\": 15.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.02334674738643172, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.3901, \"times_seen\": 8.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.0095829048540051, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.2646, \"times_seen\": 3.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.007277921907774517, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.02040995690230217, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -0.4395, \"times_seen\": 11.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.0037146200340793453, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -0.1603, \"times_seen\": 17.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.0066161594590359194, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.00602438477496397, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.3861, \"times_seen\": 5.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.004126939481493121, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -0.0333, \"times_seen\": 7.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": 0.0016121691058116803, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.1817, \"times_seen\": 3.0}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.006233701914221748, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": 0.0932, \"times_seen\": 4.0}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.0004026362409961207, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -0.5141, \"times_seen\": 19.0}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.0009509205863625903, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -0.3151, \"times_seen\": 4.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.006754132804604264, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -0.2975, \"times_seen\": 2.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.006750748503041022, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -1.7201, \"times_seen\": 2.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0027271514629170503, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": 0.0086, \"times_seen\": 3.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.005498119191375926, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -1.5347, \"times_seen\": 5.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": 0.009787527045730814, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -0.0491, \"times_seen\": 3.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.048899216853420205, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.766, \"times_seen\": 11.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.038063427060270744, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -1.3191, \"times_seen\": 21.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.001777580501030543, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.3064, \"times_seen\": 9.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.879436970056519, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.0774, \"times_seen\": 61.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.008943743470635956, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.4701, \"times_seen\": 3.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.008777993567182361, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.2046, \"times_seen\": 5.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.0062791461422945245, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.2332, \"times_seen\": 11.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.06263360630047372, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.829, \"times_seen\": 17.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.002696016961554637, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.8279, \"times_seen\": 30.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.03222079929093876, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.4157, \"times_seen\": 4.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.04794007959410085, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.4902, \"times_seen\": 37.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": 0.007497662563672053, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.0512, \"times_seen\": 3.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.008535370239868122, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.6862, \"times_seen\": 3.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.010623743864231601, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.0955, \"times_seen\": 5.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.008849071163545157, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -2.7158, \"times_seen\": 3.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 0.02054341509670832, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.4214, \"times_seen\": 3.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.005264668286103382, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.1099, \"times_seen\": 24.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.03068255694521975, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.1306, \"times_seen\": 14.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": 0.015155130455090923, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.3906, \"times_seen\": 2.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.0032173245800606936, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.0518, \"times_seen\": 11.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.07738892666590981, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.1149, \"times_seen\": 28.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.030928013642912276, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.0312, \"times_seen\": 19.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.02633168348743753, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.0043, \"times_seen\": 8.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.06503617438627901, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.3514, \"times_seen\": 25.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.028845530689780182, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.1477, \"times_seen\": 15.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.031635045750732345, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.4062, \"times_seen\": 25.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.6496270324352948, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": 0.1263, \"times_seen\": 17.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.8890375261049216, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.1915, \"times_seen\": 12.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.012880614619038168, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": 0.0096, \"times_seen\": 15.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.014233428955963901, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -1.267, \"times_seen\": 5.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.003013297937348957, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.1502, \"times_seen\": 4.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.0631075616979784, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.5554, \"times_seen\": 14.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.014937507091041306, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.1551, \"times_seen\": 11.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.022669212048149617, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.1412, \"times_seen\": 19.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.02427338825140483, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.082, \"times_seen\": 6.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.01815853651661074, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.1726, \"times_seen\": 8.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.6895503887413553, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.2061, \"times_seen\": 26.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.002545027796250857, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.082, \"times_seen\": 10.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.017322910552603352, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.2985, \"times_seen\": 10.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.00841919667299018, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.2188, \"times_seen\": 18.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.07648175535876635, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": 0.0767, \"times_seen\": 35.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.034505741926862114, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7802, \"times_seen\": 23.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.006984046431065597, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -1.1521, \"times_seen\": 26.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.0024765222632846464, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": 0.0399, \"times_seen\": 11.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": 0.577756401846314, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.3491, \"times_seen\": 9.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.017229453416786465, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.5532, \"times_seen\": 7.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.051147463232576997, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": 0.2633, \"times_seen\": 110.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": -0.012503288384452351, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7006, \"times_seen\": 8.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.025915078899771734, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.4102, \"times_seen\": 41.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.06038686308471279, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7068, \"times_seen\": 20.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.4661720737955625, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -1.0156, \"times_seen\": 30.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.00536462692747997, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.6356, \"times_seen\": 15.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.20012823590141288, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.5575, \"times_seen\": 54.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.01862321357796177, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -2.0002, \"times_seen\": 6.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.00161980158990188, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.3979, \"times_seen\": 7.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.05656340986108029, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7631, \"times_seen\": 62.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.05605836357779007, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.017, \"times_seen\": 27.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.06332748270648784, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.6807, \"times_seen\": 12.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.013306288290925073, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7585, \"times_seen\": 13.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.04014529170328246, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -1.1562, \"times_seen\": 18.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": -0.002949924148129098, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -2.1747, \"times_seen\": 1.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.0014164347082544105, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.1731, \"times_seen\": 13.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.01828110554902121, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.1107, \"times_seen\": 5.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.011981153809421377, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.7483, \"times_seen\": 11.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.0005073074784586844, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.3921, \"times_seen\": 19.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.00015628045925453326, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.3986, \"times_seen\": 48.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.018524036990786315, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.3278, \"times_seen\": 7.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.007248057854454499, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -2.9512, \"times_seen\": 2.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.008967553043586447, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": 0.2028, \"times_seen\": 19.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.023481859633397505, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -0.5388, \"times_seen\": 8.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.007834799555938028, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -2.9839, \"times_seen\": 2.0}, {\"site\": 813, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.0033118040124721655, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -3.0622, \"times_seen\": 1.0}, {\"site\": 813, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.003439853221427844, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.7514, \"times_seen\": 1.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.0037695567126329594, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.008624789687668036, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.011597973621153976, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.0834, \"times_seen\": 25.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.016205389627522864, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.2055, \"times_seen\": 6.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.015068006634494618, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.010433226837618558, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": -0.2441, \"times_seen\": 3.0}, {\"site\": 815, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.00013180711913895877, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -2.8434, \"times_seen\": 1.0}, {\"site\": 815, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.0028713125433217786, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.0312, \"times_seen\": 1.0}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.009074104560100863, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -1.8798, \"times_seen\": 2.0}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.14973956118045229, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.0993, \"times_seen\": 3.0}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.019314157158804416, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.1785, \"times_seen\": 1.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.02080211836492635, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.2577, \"times_seen\": 2.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.012285810081568416, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -0.1336, \"times_seen\": 4.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.0013424743492948309, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -1.7228, \"times_seen\": 2.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.004697571259487792, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -0.7693, \"times_seen\": 1.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.21476340251020798, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -0.8352, \"times_seen\": 37.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.01092276486444686, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.0232, \"times_seen\": 2.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.0016324535013400258, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": 0.1336, \"times_seen\": 11.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.022233645073190277, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -0.5161, \"times_seen\": 9.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.010539537945532038, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -1.8992, \"times_seen\": 4.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.005574634073661439, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -1.7887, \"times_seen\": 2.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0014032992962774177, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -2.6414, \"times_seen\": 1.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.00703365355460916, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -0.3849, \"times_seen\": 17.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.006094418027153859, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -2.4362, \"times_seen\": 2.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.559160524365119, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -0.815, \"times_seen\": 4.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0147191661326845, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -0.6487, \"times_seen\": 6.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.005634242744989332, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -2.6705, \"times_seen\": 1.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0037394385669569084, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.7285, \"times_seen\": 1.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.01861798161192484, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -2.1796, \"times_seen\": 4.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.017590174766437146, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -2.2322, \"times_seen\": 3.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.011190518353350248, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -2.1635, \"times_seen\": 1.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.6636331204863987, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": 0.0194, \"times_seen\": 28.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.008282178264098453, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.273, \"times_seen\": 14.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.009399171555136763, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -1.0801, \"times_seen\": 3.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.008243047996500066, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -0.5735, \"times_seen\": 7.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.0025434631690864724, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.1575, \"times_seen\": 1.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.002186231965586566, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.2537, \"times_seen\": 7.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.01094733491365554, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.08736371769328065, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -1.385, \"times_seen\": 12.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.015483599940941476, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -1.0352, \"times_seen\": 13.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.003841776673089162, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -1.034, \"times_seen\": 1.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.00397314188838667, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -2.8967, \"times_seen\": 1.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.009495873733375551, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.0144, \"times_seen\": 4.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.024132210980911374, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.3462, \"times_seen\": 15.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.019123639048416727, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -1.3643, \"times_seen\": 4.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.033636989019204075, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -2.364, \"times_seen\": 4.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.012258927656662685, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -0.3888, \"times_seen\": 6.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.04761620209984328, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -0.625, \"times_seen\": 45.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.006060951954614653, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -0.2696, \"times_seen\": 16.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.008106536534463691, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -2.0156, \"times_seen\": 3.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.05398000034015829, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.6488, \"times_seen\": 46.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.03366220161325657, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.916, \"times_seen\": 8.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.028239469769732434, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.2732, \"times_seen\": 48.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.01139561412120909, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -1.6449, \"times_seen\": 4.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.004642651295555143, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.3136, \"times_seen\": 3.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.002051171345318166, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.2808, \"times_seen\": 17.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.006537738782488243, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -2.4549, \"times_seen\": 2.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.04155389476842828, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.2707, \"times_seen\": 22.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.7137025471566433, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.0602, \"times_seen\": 15.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.017655717832112616, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.1565, \"times_seen\": 8.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.012267394465292897, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": -2.2066, \"times_seen\": 1.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.01714250835488752, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.15041057271375777, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -0.4038, \"times_seen\": 20.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.003548747102258998, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -1.0234, \"times_seen\": 1.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.015514036835387707, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.0163, \"times_seen\": 4.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.009155115841755997, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.0185, \"times_seen\": 53.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.016552285402400186, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.059, \"times_seen\": 60.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.10422067023376574, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -0.3378, \"times_seen\": 95.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -2.898553715222922, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.7465, \"times_seen\": 18.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.20949324747788073, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.7345, \"times_seen\": 41.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.01024898981916709, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.7527, \"times_seen\": 3.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.07779154174660696, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.3931, \"times_seen\": 32.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.008881113891191202, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.811, \"times_seen\": 5.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.013571583207542056, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -2.2549, \"times_seen\": 2.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.01120551397897915, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.3214, \"times_seen\": 5.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.008138765234255422, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.3884, \"times_seen\": 22.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.007072201609007228, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.3178, \"times_seen\": 8.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": 0.008511935496545688, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -0.0031, \"times_seen\": 11.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.04035520975059975, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.3553, \"times_seen\": 16.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.29237464922002776, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.0957, \"times_seen\": 74.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.003837377287663062, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -0.7777, \"times_seen\": 42.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.00187182280902156, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.0156, \"times_seen\": 1.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.06861293180078576, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.1105, \"times_seen\": 49.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 0.019301470898280458, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.7725, \"times_seen\": 1.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.28207039371565074, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.731, \"times_seen\": 29.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.01995395769704673, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -1.0164, \"times_seen\": 6.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"H\", \"escape\": 0.006630970411098916, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -1.5015, \"times_seen\": 3.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.02018259822607134, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.0113, \"times_seen\": 5.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.02099231834626832, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": 0.1191, \"times_seen\": 16.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.03324533879118643, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.1784, \"times_seen\": 12.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.003629086012484272, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.0873, \"times_seen\": 1.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"W\", \"escape\": -0.013222964856152078, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.4468, \"times_seen\": 8.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.019314373435937428, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": 0.098, \"times_seen\": 5.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.033406265125092746, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.1099, \"times_seen\": 16.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.07791090759653524, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.0544, \"times_seen\": 8.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.020385285661382348, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.1654, \"times_seen\": 17.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.025394763547541686, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -0.1605, \"times_seen\": 6.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.044984086191985684, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -0.0861, \"times_seen\": 23.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.0019237810707145866, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.3875, \"times_seen\": 15.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.029426767703014448, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": 0.2586, \"times_seen\": 26.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": 0.0011253695647383763, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.5358, \"times_seen\": 4.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.013938981457972986, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.2355, \"times_seen\": 5.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.014993806415888912, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.5423, \"times_seen\": 10.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.05144110551694678, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.4526, \"times_seen\": 13.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.011354146737973964, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.0165, \"times_seen\": 61.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.001438318875146651, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.0234, \"times_seen\": 10.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.011385090418393517, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.1667, \"times_seen\": 16.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.7365640439651135, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.4189, \"times_seen\": 47.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.022104003093284575, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.2839, \"times_seen\": 15.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.07289961190244856, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": 0.1973, \"times_seen\": 37.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"M\", \"escape\": -0.031514001643949664, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": 0.3236, \"times_seen\": 7.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.006472441656176629, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.4693, \"times_seen\": 8.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.05038290322815547, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.1702, \"times_seen\": 23.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": 0.022870221556977426, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -2.9421, \"times_seen\": 1.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.013860168489129212, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -2.569, \"times_seen\": 3.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.11124633314061687, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -0.1285, \"times_seen\": 21.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.018058907119538885, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -0.2107, \"times_seen\": 12.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.011450329219918233, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -1.874, \"times_seen\": 4.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.016035902395672555, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -0.9393, \"times_seen\": 2.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -0.0038325185998628595, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -2.1686, \"times_seen\": 1.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"W\", \"escape\": -0.0029793844265650843, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": 0.0472, \"times_seen\": 9.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.012255638738181765, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 1.8104046178469584, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -1.8205, \"times_seen\": 3.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.033772284759158985, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.0613, \"times_seen\": 24.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.08234285945731981, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.3981, \"times_seen\": 21.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.0015091759342205828, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -1.2886, \"times_seen\": 2.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.14240484760897507, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.3667, \"times_seen\": 36.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.024613026447282128, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": 0.3395, \"times_seen\": 21.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.011922777131534284, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.8123, \"times_seen\": 5.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.0030031830369273596, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.9998, \"times_seen\": 2.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.07763361429520932, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.4425, \"times_seen\": 31.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 1.3538529141409832, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.9107, \"times_seen\": 21.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.005551030655492329, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.3722, \"times_seen\": 1.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.03310445573547851, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.0207, \"times_seen\": 28.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.01678427122291081, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.0149, \"times_seen\": 7.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.004753457327420542, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.6912, \"times_seen\": 4.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.029127606583644855, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.0975, \"times_seen\": 11.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.024858425541409743, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.5629, \"times_seen\": 24.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"A\", \"escape\": -0.003171280327560596, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.8542, \"times_seen\": 1.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": -0.008944012972346744, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.2287, \"times_seen\": 3.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.004114146455174042, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -1.4463, \"times_seen\": 1.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.012133416072160922, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.8114, \"times_seen\": 4.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": 0.009723806398660524, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.6818, \"times_seen\": 4.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.014959239545114937, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": 0.0767, \"times_seen\": 28.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.039428184775910834, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.1726, \"times_seen\": 30.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.010887688942189016, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.2628, \"times_seen\": 6.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": 0.016910041355006598, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -1.1094, \"times_seen\": 10.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.014970529219389517, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -2.31, \"times_seen\": 2.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.008449792717442032, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.888, \"times_seen\": 1.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -2.598500068507278, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.6282, \"times_seen\": 16.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.008008363975007976, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.2603, \"times_seen\": 11.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.008221616627955545, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.6956, \"times_seen\": 4.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.021971725597523285, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.1825, \"times_seen\": 48.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.057108203195745104, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.054, \"times_seen\": 16.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": 0.04126560537090095, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.1613, \"times_seen\": 17.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.09180936930506792, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.4444, \"times_seen\": 21.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.04228974743928709, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.0344, \"times_seen\": 21.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.056424676186608555, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.1463, \"times_seen\": 48.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.03460533972804035, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.0316, \"times_seen\": 8.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.0621337401270862, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.0822, \"times_seen\": 5.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.03704803939604128, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.1265, \"times_seen\": 22.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.005986722071482334, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.8541, \"times_seen\": 23.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.07311784894317287, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.305, \"times_seen\": 12.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.03947079389891813, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.0364, \"times_seen\": 62.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.023919656326467673, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.6549, \"times_seen\": 16.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.002146847048985556, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.5269, \"times_seen\": 9.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.026015741867211905, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.11, \"times_seen\": 6.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.042352416471926065, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.1671, \"times_seen\": 31.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.012343245746152545, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.4068, \"times_seen\": 4.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.015263786729386589, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.8194, \"times_seen\": 8.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.06376915397678179, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.5731, \"times_seen\": 22.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.04103175077100006, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.1602, \"times_seen\": 26.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.002657209344247195, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -2.6345, \"times_seen\": 22.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.2977814362873074, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.1338, \"times_seen\": 60.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.12701018524105545, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.6906, \"times_seen\": 42.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.27968642221363477, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.4706, \"times_seen\": 24.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.006305732890968693, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.2424, \"times_seen\": 131.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.45999981106937265, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.777, \"times_seen\": 25.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": 0.02305874900264678, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.1839, \"times_seen\": 41.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.0030915478018073645, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.6403, \"times_seen\": 30.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -1.5862718173520831, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.7181, \"times_seen\": 72.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.05447132137023886, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.1965, \"times_seen\": 30.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": 0.02836122909753797, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9794, \"times_seen\": 41.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.0441585994683951, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.4868, \"times_seen\": 44.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.03895797515804926, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9328, \"times_seen\": 33.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": 0.3859219068388137, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.2054, \"times_seen\": 111.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.15196114585920553, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.5428, \"times_seen\": 157.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.39994867400070355, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9665, \"times_seen\": 122.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.09413924714276711, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9245, \"times_seen\": 183.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": 0.06402438073126059, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.6397, \"times_seen\": 21.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.36140584065995557, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.367, \"times_seen\": 24.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": 0.034458484651714784, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -3.0735, \"times_seen\": 3.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.028068893364814523, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.79, \"times_seen\": 8.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.059446869971116215, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.749, \"times_seen\": 29.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.026950265317150075, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.0106, \"times_seen\": 29.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": 1.564287383454009, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.4673, \"times_seen\": 22.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.009369685216436755, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.0724, \"times_seen\": 152.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.006115888150649535, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.6658, \"times_seen\": 25.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": 0.03282871916896729, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -0.9476, \"times_seen\": 27.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": 0.6160309159520051, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.8952, \"times_seen\": 15.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.4008082389482303, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.2763, \"times_seen\": 74.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.21962741384813658, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.2994, \"times_seen\": 27.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.0021230992118053487, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.338, \"times_seen\": 19.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.02434281901951974, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -0.0578, \"times_seen\": 64.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.030775275898072454, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.8253, \"times_seen\": 23.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.10663711210382293, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.6611, \"times_seen\": 90.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.4769344496166093, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.6539, \"times_seen\": 134.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.009272747008127665, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.208, \"times_seen\": 117.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.4433529518728763, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -0.3525, \"times_seen\": 118.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": 0.4571379071564076, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.5017, \"times_seen\": 24.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": 0.05537114799536575, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.3419, \"times_seen\": 17.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.019821339461754874, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.5419, \"times_seen\": 10.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.028182148900586776, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.5694, \"times_seen\": 12.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.019713841100495382, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.5871, \"times_seen\": 10.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.10452747242337539, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -0.6712, \"times_seen\": 39.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": 0.039506131465268955, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.5409, \"times_seen\": 14.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.034452383647638536, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.2483, \"times_seen\": 4.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.03274972003450005, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.5557, \"times_seen\": 16.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.017910646260788782, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.5772, \"times_seen\": 9.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.036531412812413386, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.6551, \"times_seen\": 10.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.03450024878682504, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.2437, \"times_seen\": 31.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.453222757773024, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.9922, \"times_seen\": 9.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.10081830485541067, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.7239, \"times_seen\": 27.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": 0.1110995184052111, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.7619, \"times_seen\": 6.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.008052145255888684, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.879, \"times_seen\": 5.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.001930661964088683, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.8739, \"times_seen\": 2.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.023915674557754667, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.2632, \"times_seen\": 19.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.00019749792502555573, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.4326, \"times_seen\": 10.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.05939114727904084, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -1.7226, \"times_seen\": 33.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.006927088826928078, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -1.5231, \"times_seen\": 36.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.30359131632165365, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.7332, \"times_seen\": 32.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.042349216098831494, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -0.5665, \"times_seen\": 15.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.08978513287432306, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -0.7579, \"times_seen\": 37.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.008948118759386146, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -2.5023, \"times_seen\": 3.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.004168702729202018, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -1.3863, \"times_seen\": 1.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.017353746873611662, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -1.5783, \"times_seen\": 7.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.03705860268112273, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -0.7984, \"times_seen\": 38.0}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"I\", \"escape\": -0.008333403144278452, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.8686, \"times_seen\": 3.0}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.0025482307634872416, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.9829, \"times_seen\": 2.0}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": -0.0017558226561437895, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -3.064, \"times_seen\": 1.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.010840504034314701, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -2.2183, \"times_seen\": 1.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.02247958012504589, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -1.4741, \"times_seen\": 16.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.0011370401553247604, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -1.7418, \"times_seen\": 12.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.0012017838613213043, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": 0.1227, \"times_seen\": 6.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.10241121006811092, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -0.76, \"times_seen\": 32.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.6260029836650284, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -0.281, \"times_seen\": 62.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.1046558053695897, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": 0.0462, \"times_seen\": 58.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.007619040476271818, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.5227, \"times_seen\": 15.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.021426414616921116, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.1194, \"times_seen\": 16.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.01070262435405656, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -1.3369, \"times_seen\": 24.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.0160418892197199, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.1023, \"times_seen\": 15.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.002305636508363843, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.2598, \"times_seen\": 27.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.010419982159967336, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -2.41, \"times_seen\": 9.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.011109191500183123, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -2.0602, \"times_seen\": 20.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.059784182581179145, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -1.6936, \"times_seen\": 15.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.04587790762710488, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -0.1584, \"times_seen\": 27.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.008388413371768697, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -2.4184, \"times_seen\": 3.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.052037850250024366, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -1.8308, \"times_seen\": 8.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": 0.0008985344607904203, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -1.312, \"times_seen\": 1.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.006866710441780091, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -2.5032, \"times_seen\": 1.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.3590326234836287, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": 0.3644, \"times_seen\": 38.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.05764917899142869, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -0.5995, \"times_seen\": 73.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0020416033701452906, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -1.4274, \"times_seen\": 6.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": 0.4442488400083396, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.9125, \"times_seen\": 92.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": 0.0037591095194874687, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -1.5977, \"times_seen\": 26.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": -0.0072563405911326056, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.5873, \"times_seen\": 3.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.019264250986136003, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.3979, \"times_seen\": 15.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": -0.042166748991295, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.1267, \"times_seen\": 41.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.026075771317033963, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.3544, \"times_seen\": 14.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.08671639121992405, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": 0.0791, \"times_seen\": 70.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.007695387754173737, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.1387, \"times_seen\": 18.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.05496696358147975, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.0955, \"times_seen\": 61.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.3757016335135635, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.4447, \"times_seen\": 16.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.10081719107807056, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -1.7298, \"times_seen\": 64.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 0.004144300802326008, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.5298, \"times_seen\": 14.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.002491627237832227, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.2424, \"times_seen\": 17.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.06024896111251499, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.6447, \"times_seen\": 224.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.43713369849878114, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -1.9095, \"times_seen\": 79.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.0020592956057623652, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.1544, \"times_seen\": 24.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.1774302902120515, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.8934, \"times_seen\": 83.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": 0.020758024479788036, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.3892, \"times_seen\": 43.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": 0.1187533648873219, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.8007, \"times_seen\": 50.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": 0.008145897306457506, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.8102, \"times_seen\": 5.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": 1.8489679808028805, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.5312, \"times_seen\": 1.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.0006691630497804734, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -2.9628, \"times_seen\": 2.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0008690421951819858, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -1.1154, \"times_seen\": 1.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.0035626828106115967, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -2.289, \"times_seen\": 1.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.004238092724670297, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -1.0823, \"times_seen\": 2.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.003761127564971893, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -2.1181, \"times_seen\": 1.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": 0.001575568156256307, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -2.5774, \"times_seen\": 1.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.03746346524029142, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -2.1564, \"times_seen\": 24.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.011230401581475037, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -2.7938, \"times_seen\": 2.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.012052138205125136, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": 0.4444, \"times_seen\": 39.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.008703711911331572, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -0.3922, \"times_seen\": 3.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.00454426912751281, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -1.7526, \"times_seen\": 2.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.044907696567122804, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -0.1563, \"times_seen\": 18.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.15177616771733154, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.5444, \"times_seen\": 104.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.10938471079109736, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.5342, \"times_seen\": 15.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.12826925463032302, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.6204, \"times_seen\": 27.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": 0.00842869915469899, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.2778, \"times_seen\": 11.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.08358986662079819, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.4182, \"times_seen\": 26.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": -0.05509867682167521, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": 0.4027, \"times_seen\": 39.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": 0.21389084487338636, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.7925, \"times_seen\": 35.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.02129452714690404, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.5402, \"times_seen\": 73.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.11840279226028934, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -2.407, \"times_seen\": 25.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.03882608746718044, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.3142, \"times_seen\": 73.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.36571870633723946, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.0852, \"times_seen\": 36.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.036248156280736375, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.2957, \"times_seen\": 82.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.01798111627837165, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -2.7071, \"times_seen\": 11.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.028939936358656413, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.4345, \"times_seen\": 27.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.14958791280010847, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.6237, \"times_seen\": 60.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.07961154072178904, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.0987, \"times_seen\": 123.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": 0.006836294345771377, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.8602, \"times_seen\": 67.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": -0.08036673743109794, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.871, \"times_seen\": 23.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": -0.04509358299462103, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.9994, \"times_seen\": 38.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.1504814182769027, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -2.6513, \"times_seen\": 8.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.017207399757673617, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -0.6694, \"times_seen\": 6.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.3209979674046684, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.0019949798954158574, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.1868, \"times_seen\": 39.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0780888855874354, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.2905, \"times_seen\": 100.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.6884882957541425, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.4342, \"times_seen\": 18.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": 0.0685832032892222, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -0.421, \"times_seen\": 16.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.004123507365070542, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -1.7347, \"times_seen\": 7.0}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.03341431778119857, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -1.5722, \"times_seen\": 6.0}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.04358974310907146, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -0.4802, \"times_seen\": 16.0}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.028291414027379853, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -1.3433, \"times_seen\": 13.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.07301436374287194, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -0.7611, \"times_seen\": 24.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.057630293047450126, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.0231, \"times_seen\": 15.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"K\", \"escape\": -0.003924494810544486, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.3384, \"times_seen\": 3.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.006397008325245958, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.0846, \"times_seen\": 4.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.009950923068119687, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -0.919, \"times_seen\": 5.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.025958936226385627, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.0717, \"times_seen\": 33.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.016613542101844087, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -0.7747, \"times_seen\": 17.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.012224154395469556, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -1.96, \"times_seen\": 5.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.04500162588757029, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -2.6658, \"times_seen\": 8.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.002653589150250574, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -0.6719, \"times_seen\": 1.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.11026456690851115, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -0.9811, \"times_seen\": 17.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.004822589404545506, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -2.9445, \"times_seen\": 1.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.028603513340341013, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.6214, \"times_seen\": 5.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.01126347525527, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -1.0673, \"times_seen\": 2.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.01019890876805503, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -0.7441, \"times_seen\": 4.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.0028449374894290182, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -1.5503, \"times_seen\": 13.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": -0.009521107592689048, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.7774, \"times_seen\": 3.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": 0.004694808758474132, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.018, \"times_seen\": 5.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.009869453756251511, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -0.432, \"times_seen\": 24.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0028348325268896693, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -0.1443, \"times_seen\": 3.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.01339635979679233, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -1.6943, \"times_seen\": 1.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.007504830000512328, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -1.8864, \"times_seen\": 4.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.005452899757645012, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -2.383, \"times_seen\": 2.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.0028427822496452566, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -1.4373, \"times_seen\": 1.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.0022041569587346677, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -3.0869, \"times_seen\": 1.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.0035461903680851898, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -2.9688, \"times_seen\": 2.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.05599100265216033, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -0.8521, \"times_seen\": 4.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.027273773257088248, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -0.8765, \"times_seen\": 21.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.00895570602052856, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -1.2687, \"times_seen\": 6.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.008810233160595555, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.1439, \"times_seen\": 5.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.1165060548214144, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.6771, \"times_seen\": 15.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.03039495150958561, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -0.9305, \"times_seen\": 25.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.06388364134418796, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -0.5879, \"times_seen\": 47.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.010755673971924408, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -0.928, \"times_seen\": 6.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.021115143139083498, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.4787, \"times_seen\": 7.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.0835353159019964, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.1107, \"times_seen\": 51.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.004085673967791152, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": 0.4116, \"times_seen\": 11.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.001911688781829828, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.8784, \"times_seen\": 12.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.7016304570187795, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.0776, \"times_seen\": 23.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.07091193059132976, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.8603, \"times_seen\": 28.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"L\", \"escape\": -0.021884970006049873, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.0227, \"times_seen\": 19.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.7720990345020828, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.1754, \"times_seen\": 16.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": 0.05321961707669503, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": 0.0639, \"times_seen\": 11.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"T\", \"escape\": -0.023977227615250674, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.2828, \"times_seen\": 10.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.05146438194760842, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.0615, \"times_seen\": 19.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"F\", \"escape\": 0.01894606006683031, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.9106, \"times_seen\": 5.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": 0.004953087091025646, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -2.1834, \"times_seen\": 43.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"K\", \"escape\": -0.0011948778573667095, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -2.8871, \"times_seen\": 1.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.01477150708735892, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.9617, \"times_seen\": 13.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.007146990632516272, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -2.0013, \"times_seen\": 2.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"A\", \"escape\": -0.004696793665771482, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": -0.03838775113995625, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -2.5393, \"times_seen\": 18.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0023854741254229392, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -0.2995, \"times_seen\": 8.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.009140402304911097, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -2.73, \"times_seen\": 3.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.04309633476972134, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -1.9914, \"times_seen\": 7.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.025517424377178587, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -1.265, \"times_seen\": 16.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.6157290055514806, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -0.5048, \"times_seen\": 13.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.030070863449711046, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -0.8446, \"times_seen\": 16.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.006965499887426186, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -2.239, \"times_seen\": 8.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.02714659487446738, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.8396, \"times_seen\": 40.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.06166939124480956, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.8136, \"times_seen\": 42.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.4876251862112853, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -0.9823, \"times_seen\": 63.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.014282930617826144, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -2.6765, \"times_seen\": 18.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.01849457559385723, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -2.8286, \"times_seen\": 14.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.008804279839817027, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.0028719092050600824, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -2.8946, \"times_seen\": 11.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.008822878011585846, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -1.2791, \"times_seen\": 1.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.011474277567897664, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.2976, \"times_seen\": 5.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.01825066547451214, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.5511, \"times_seen\": 4.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.009109014823607956, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.6485, \"times_seen\": 3.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": 0.02131500763127459, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.876, \"times_seen\": 3.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.021729739579931257, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.8302, \"times_seen\": 2.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.0234927861628252, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -1.3152, \"times_seen\": 28.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.7490342002418829, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.4757, \"times_seen\": 60.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.005867915214160405, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.05141714378677742, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -2.4005, \"times_seen\": 26.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.0015065143179618097, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.8241, \"times_seen\": 13.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.0043349365404619705, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.5853, \"times_seen\": 10.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.03178347365587136, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -0.0026546146299484034, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.9798, \"times_seen\": 5.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.0019239548497276583, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.3565, \"times_seen\": 7.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.015750205514568932, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.6843, \"times_seen\": 5.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.010752508727077352, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.8007, \"times_seen\": 6.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.01674806021152241, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -1.976, \"times_seen\": 7.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.003948761230589019, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.1349, \"times_seen\": 4.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.0015169804558419308, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -1.8838, \"times_seen\": 3.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.043657844594709304, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.0013208620565730318, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -1.912, \"times_seen\": 18.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.729279011164219, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -2.9086, \"times_seen\": 20.0}, {\"site\": 874, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.254421826589007, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -0.3375, \"times_seen\": 23.0}, {\"site\": 874, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.06889690604526237, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -2.0821, \"times_seen\": 4.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.03829291959915294, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -0.2397, \"times_seen\": 19.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0043346807151567, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": 0.193, \"times_seen\": 2.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.07495466898869495, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.026548178218358667, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -0.3973, \"times_seen\": 17.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.027926296270399012, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -1.3348, \"times_seen\": 5.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.01028043976714883, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -2.5662, \"times_seen\": 3.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.05398683096974653, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -1.8807, \"times_seen\": 5.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.011976735031166162, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -2.1241, \"times_seen\": 11.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.13794867014260245, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -2.8638, \"times_seen\": 6.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.01986488870328452, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -0.6351, \"times_seen\": 23.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.09254489464942467, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -1.6446, \"times_seen\": 62.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.007355867658271084, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -0.8753, \"times_seen\": 50.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.013084875864827225, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.5512, \"times_seen\": 5.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.017778405511599756, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.8455, \"times_seen\": 4.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": 0.03001348908866259, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.9677, \"times_seen\": 4.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.003481745374069237, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.2973, \"times_seen\": 1.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.004220920471792526, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.0185, \"times_seen\": 2.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.46578299990951555, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -1.2638, \"times_seen\": 35.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": 0.06414758338005057, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -1.4343, \"times_seen\": 13.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.004301953292050133, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -0.3877, \"times_seen\": 36.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.001810660518853199, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -2.9447, \"times_seen\": 2.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.0007735148429867011, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -2.7151, \"times_seen\": 2.0}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.0034847153620255395, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -0.3617, \"times_seen\": 15.0}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.011497434423818625, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -2.4807, \"times_seen\": 4.0}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.021660427560811945, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -1.8263, \"times_seen\": 23.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.08147760436611048, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -2.1703, \"times_seen\": 16.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.48954969763497935, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": 0.1604, \"times_seen\": 66.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.004051428154625368, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -1.9154, \"times_seen\": 1.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.0021240022595086726, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -2.556, \"times_seen\": 5.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.010003476340210824, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -2.1828, \"times_seen\": 34.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": 0.02463365600589923, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": 0.3069, \"times_seen\": 16.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0009787320196319208, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.6929, \"times_seen\": 17.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.187005657744957, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.0416, \"times_seen\": 71.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.011369193687053608, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.9622, \"times_seen\": 58.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.0014962255308297759, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -3.0951, \"times_seen\": 3.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.0086261557962781, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -2.5014, \"times_seen\": 5.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.0022348973074052384, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": 0.2088, \"times_seen\": 1.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.01594682254812282, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.6158, \"times_seen\": 5.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.038860810543132424, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -1.9734, \"times_seen\": 12.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.031963386642384385, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": 0.3778, \"times_seen\": 18.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.010434889960673531, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -2.6946, \"times_seen\": 3.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.03729639159934221, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -1.3894, \"times_seen\": 10.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.0028094095725293175, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -1.2089, \"times_seen\": 5.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.050256176556936115, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -0.9062, \"times_seen\": 10.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": 0.008032278453234308, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": 0.0434, \"times_seen\": 2.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": -0.2856565740335692, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": 0.0778, \"times_seen\": 29.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.04198638165764666, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -2.9759, \"times_seen\": 16.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"Y\", \"escape\": 0.0010335901175335443, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -0.2983, \"times_seen\": 9.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": -0.01841019697503473, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -2.5819, \"times_seen\": 6.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.011047459629790382, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -1.8786, \"times_seen\": 10.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.04726003985089354, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.6117, \"times_seen\": 19.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.0082264803220566, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -1.2449746438803766, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.577, \"times_seen\": 13.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.038954500831281304, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"A\", \"escape\": -0.003257496588861832, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -1.1316, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.0035506534078227282, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.635, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"G\", \"escape\": -0.006558147544269904, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.454, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.0015452791161794962, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.1789, \"times_seen\": 31.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.057999690536056595, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -1.6337, \"times_seen\": 33.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.002458643073385711, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -3.006, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.002844841116140156, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.3042, \"times_seen\": 20.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.007378661840959791, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.2256, \"times_seen\": 3.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": -0.06620640087746037, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": 0.3901, \"times_seen\": 19.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.0009310528837456468, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.6001, \"times_seen\": 2.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.014081028880478588, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -3.051, \"times_seen\": 2.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.027880431328141442, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.6684, \"times_seen\": 11.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.053789407596503046, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -0.7051, \"times_seen\": 12.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.027259907600103186, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -3.131, \"times_seen\": 4.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.0022417591176826348, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.4742, \"times_seen\": 3.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": 0.02967595063439532, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.8258, \"times_seen\": 2.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.030750562325498377, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -1.119, \"times_seen\": 15.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.0020431251271988598, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -1.2195, \"times_seen\": 8.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 2.608179100796522e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -3.2528, \"times_seen\": 1.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.7972974997264727, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": 0.1666, \"times_seen\": 25.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.01384665749804662, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -1.1744, \"times_seen\": 31.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.23991197433357417, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -0.4164, \"times_seen\": 81.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.17031667906796782, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": 0.4444, \"times_seen\": 109.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.013746294602760771, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.002049855746208173, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.9939, \"times_seen\": 3.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.003916728745205091, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.7203, \"times_seen\": 1.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.010806744249153991, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.1703, \"times_seen\": 9.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.002259252249964329, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -1.5322, \"times_seen\": 3.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.02450343675863017, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -2.5049, \"times_seen\": 2.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.0038331860664644005, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -1.2289, \"times_seen\": 1.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.04506248994037934, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -2.3039, \"times_seen\": 2.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.039229646959949814, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -0.3493, \"times_seen\": 27.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.07378328549868403, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -0.5448, \"times_seen\": 28.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.2256158609886934, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -0.6734, \"times_seen\": 93.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -3.5959610415173806, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.9218, \"times_seen\": 1.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.10845311524923329, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -0.0444, \"times_seen\": 3.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.07494736386573554, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.1832, \"times_seen\": 9.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.0434751012704857, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.3667, \"times_seen\": 7.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.027093159632944876, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.3519, \"times_seen\": 15.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.019703244931289134, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -0.4678, \"times_seen\": 11.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.0010789171484025877, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.6892, \"times_seen\": 9.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.016626668836294257, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.8638, \"times_seen\": 3.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0038325919296100155, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.005027076383328003, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.0644, \"times_seen\": 2.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.004071705887819935, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -1.3112, \"times_seen\": 1.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.027314605280223836, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -0.7551, \"times_seen\": 18.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.0036422048825464335, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.1146, \"times_seen\": 14.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.003774353172073766, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.9371, \"times_seen\": 1.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.003986554938562822, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.7823, \"times_seen\": 1.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0066214506032034595, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -1.1891, \"times_seen\": 2.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.004099450226894782, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -1.5844, \"times_seen\": 9.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"R\", \"escape\": 0.01036314620016146, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -2.6707, \"times_seen\": 3.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.01776380238486485, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -2.4205, \"times_seen\": 12.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.009019745808200539, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -1.8276, \"times_seen\": 4.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.007938040619487973, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.9962, \"times_seen\": 1.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": -1.033120537783335, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.696, \"times_seen\": 3.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.01387917813542302, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.8016, \"times_seen\": 2.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.007608335106946092, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.7618, \"times_seen\": 2.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.0022353807543389875, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -3.0526, \"times_seen\": 3.0}, {\"site\": 895, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.0029377626963284823, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -2.7561, \"times_seen\": 2.0}, {\"site\": 895, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.00275554001786209, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -0.7948, \"times_seen\": 1.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.0032561835421120637, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -2.8743, \"times_seen\": 1.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.020548414104303695, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -1.9038, \"times_seen\": 6.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.0533227514429802, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -1.4036, \"times_seen\": 14.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.08838949674678347, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -1.3045, \"times_seen\": 32.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.002783563765964023, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -0.7626, \"times_seen\": 18.0}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": 0.25380568548944826, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -1.8462, \"times_seen\": 31.0}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": 0.18661357323877162, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -1.6964, \"times_seen\": 5.0}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"Q\", \"escape\": 0.01331552799766455, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -2.7554, \"times_seen\": 7.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.02035998887852898, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.9477, \"times_seen\": 4.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.06314677183263193, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.5577, \"times_seen\": 7.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.020847517763671802, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.8476, \"times_seen\": 1.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": -0.005704326579773449, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"V\", \"escape\": -0.0015942207744336929, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": 0.020899796242760442, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.6303, \"times_seen\": 1.0}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -0.005379731319268873, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -2.8048, \"times_seen\": 2.0}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": 0.005572352231143931, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -1.6681, \"times_seen\": 7.0}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": 0.008785398964660214, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.0016660192790213153, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.7687, \"times_seen\": 1.0}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.014803212077963116, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.7799, \"times_seen\": 5.0}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.004300764345469337, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.598, \"times_seen\": 4.0}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.012675016457304246, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -1.5884, \"times_seen\": 3.0}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.014898220945426761, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": 0.1966, \"times_seen\": 18.0}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.9298077166386504, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -0.7952, \"times_seen\": 21.0}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.9310416951311548, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.9103, \"times_seen\": 7.0}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 2.7704244788950327, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.5305, \"times_seen\": 5.0}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.10560598916135305, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.7124, \"times_seen\": 1.0}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.03465798730035018, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -2.4218, \"times_seen\": 2.0}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.017982846586919673, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -1.3472, \"times_seen\": 1.0}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.005382001539761862, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -2.4569, \"times_seen\": 1.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.005348427966984852, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -1.1061, \"times_seen\": 7.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.007253942840571821, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -1.3226, \"times_seen\": 6.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0035541465789929614, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -2.0818, \"times_seen\": 1.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.0034007631355700892, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -2.0047, \"times_seen\": 1.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.01005409171904744, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": 0.378, \"times_seen\": 8.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.02046334331351708, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.015698907864616748, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -1.4382, \"times_seen\": 8.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.012408705060088657, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -2.1475, \"times_seen\": 8.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.019723675519928225, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -1.2561, \"times_seen\": 1.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.021365282343301137, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": 0.2966, \"times_seen\": 6.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.011567908601565105, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -2.625, \"times_seen\": 2.0}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.015153177886141418, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -2.6475, \"times_seen\": 1.0}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.008437740712316294, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -2.758, \"times_seen\": 1.0}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.1544594859872378, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -0.2602, \"times_seen\": 39.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.01083491706927963, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.4367, \"times_seen\": 20.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.027444512446461303, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.4034, \"times_seen\": 2.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.003253925674425828, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.2281, \"times_seen\": 1.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.0032060076477154883, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.9937, \"times_seen\": 1.0}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 1.8295832143601702, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -0.9528, \"times_seen\": 13.0}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.017294764498382274, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -1.7645, \"times_seen\": 10.0}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.06976673614927048, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -2.6745, \"times_seen\": 1.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.03607080988225993, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -1.8363, \"times_seen\": 18.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.010358498400592617, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -2.7658, \"times_seen\": 5.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -1.2072104377585038, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -1.7886, \"times_seen\": 3.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.023556197789768238, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -2.2041, \"times_seen\": 4.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.05578431683705813, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -0.0022, \"times_seen\": 13.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.008324385930908784, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.2618, \"times_seen\": 3.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.030736955654663313, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.4255, \"times_seen\": 3.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.0031594646083278953, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.311, \"times_seen\": 10.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.014357612730128491, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.3632, \"times_seen\": 3.0}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.01885925504692645, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -2.6387, \"times_seen\": 2.0}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.007986480810121866, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -1.9719, \"times_seen\": 5.0}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.00634291201632606, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -2.6153, \"times_seen\": 2.0}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.0029164554787402064, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -0.4727, \"times_seen\": 26.0}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0006867835855053478, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.1996, \"times_seen\": 1.0}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.011413364416831717, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.468, \"times_seen\": 2.0}, {\"site\": 913, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.02504513397622011, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -1.7646, \"times_seen\": 29.0}, {\"site\": 914, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.04236933872377516, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -0.1498, \"times_seen\": 7.0}, {\"site\": 914, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.02039437255198082, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.4585, \"times_seen\": 3.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.045333083299482685, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -0.5814, \"times_seen\": 4.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.00027986808417839647, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.073, \"times_seen\": 7.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.0393582735275274, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -1.6992, \"times_seen\": 10.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.0936349022838885, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -1.4865, \"times_seen\": 29.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.048228159557317005, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": 0.4295, \"times_seen\": 5.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"T\", \"escape\": 0.0006492359401601125, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -1.0897, \"times_seen\": 1.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.00922798775729771, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.0003229243458338762, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.393, \"times_seen\": 2.0}, {\"site\": 916, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.001231686950654172, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.0356, \"times_seen\": 1.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.018738786649002376, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.9199, \"times_seen\": 4.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.9562072141625503, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -1.2457, \"times_seen\": 23.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.00963915395416217, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -3.1032, \"times_seen\": 1.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.009924883904843692, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.7045, \"times_seen\": 1.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.03188608854136678, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.1925, \"times_seen\": 9.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.022897778920087146, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.25, \"times_seen\": 11.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.03793449479060549, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": -0.1995, \"times_seen\": 11.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.0482861991479905, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.2591, \"times_seen\": 8.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.027321653250672956, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -0.1284, \"times_seen\": 18.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.027605907703068047, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -1.1435, \"times_seen\": 5.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.022929673933931093, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.2593, \"times_seen\": 20.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.8695290446380292, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.3547, \"times_seen\": 13.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.1615491962990823, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -0.7893, \"times_seen\": 14.0}, {\"site\": 920, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.007068349139698493, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -2.1225, \"times_seen\": 3.0}, {\"site\": 920, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.0034626202560304746, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": 0.3428, \"times_seen\": 8.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.030730543869371615, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -1.8836, \"times_seen\": 5.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.02320223131128064, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -1.6701, \"times_seen\": 1.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.021412402583998406, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.020202203598160166, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -0.5601, \"times_seen\": 19.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.5297127894899682, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -2.3407, \"times_seen\": 18.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -2.979859938997987, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -2.117, \"times_seen\": 23.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": 0.00010997773052660933, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.5035, \"times_seen\": 7.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.007300851085405319, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.1584, \"times_seen\": 20.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.07726118817292374, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -1.4171, \"times_seen\": 10.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.015025071861104676, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.7135, \"times_seen\": 14.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": 0.007017172098591548, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.7559, \"times_seen\": 5.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.02436015990271442, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.5794, \"times_seen\": 11.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.0370993521434803, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.8221, \"times_seen\": 10.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.8720280529150939, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.2915, \"times_seen\": 20.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.01883331718357307, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -1.3777, \"times_seen\": 6.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.0039581776820099305, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -1.2896, \"times_seen\": 15.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.05208098409878606, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -0.1869, \"times_seen\": 16.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": 0.007813491682077168, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.9703, \"times_seen\": 3.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": -0.00369304021566711, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.9053, \"times_seen\": 1.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.009662617371213943, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.3285, \"times_seen\": 8.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.010066377467596465, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -2.2115, \"times_seen\": 4.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.017241156899795683, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -2.0167, \"times_seen\": 5.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.006461493474109137, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -2.7049, \"times_seen\": 1.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"-\", \"escape\": -0.006051654112172921, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.019485645934598107, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.5455, \"times_seen\": 2.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.0031773463906103272, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.717, \"times_seen\": 1.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.004595293429053724, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.2128, \"times_seen\": 3.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.005647024622755083, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.004088329487953801, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.2868, \"times_seen\": 1.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.2310698822824681, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.488, \"times_seen\": 3.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.018092759274341064, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.2219, \"times_seen\": 4.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.3005430243034564, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.0993, \"times_seen\": 28.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.8244762985477506, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.1288, \"times_seen\": 20.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.01707462302819698, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -2.9645, \"times_seen\": 1.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.012608569238337636, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.2751, \"times_seen\": 7.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.009897596215688382, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.1001, \"times_seen\": 30.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.09019028548994147, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.4408, \"times_seen\": 14.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.01898131460677767, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.4279, \"times_seen\": 8.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.006499239228308036, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.00761602645644732, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.7905, \"times_seen\": 4.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.0026066780801777506, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -2.3045, \"times_seen\": 1.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.009207034263032187, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.575, \"times_seen\": 11.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.007565645088330239, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -1.8084, \"times_seen\": 3.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.025031388546108566, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.4934, \"times_seen\": 7.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.001772232279588079, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -2.9182, \"times_seen\": 1.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.024751291521809868, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -1.9236, \"times_seen\": 4.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.008857484191779568, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -2.7247, \"times_seen\": 3.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": -0.006130144428172066, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.010263755121337684, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.4695, \"times_seen\": 2.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.0004238215345547929, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.017068245496136534, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.3694, \"times_seen\": 5.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0038239756618830517, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -2.4165, \"times_seen\": 1.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.021792185816378103, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.6782, \"times_seen\": 8.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.006158159365514045, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.0031468889040998974, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.1662, \"times_seen\": 7.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.007620130498710331, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.0122, \"times_seen\": 14.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.01659266089661318, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.3633, \"times_seen\": 79.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.002261003156310843, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.1018, \"times_seen\": 8.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -0.0033499406228698586, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.0030105868522345286, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.0408, \"times_seen\": 26.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.06025470892559539, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.1759, \"times_seen\": 41.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.28745773239073036, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.2646, \"times_seen\": 18.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -5.9454324659591824e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.1853, \"times_seen\": 27.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": 0.07225070420408258, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.2353, \"times_seen\": 15.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.006073270043950776, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.05111205725298594, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.2416, \"times_seen\": 21.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.003108286445102498, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.2802, \"times_seen\": 2.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.0002726551875352888, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -0.2066, \"times_seen\": 4.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.005761345664913392, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.3491, \"times_seen\": 11.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.042327482060487594, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.0968, \"times_seen\": 16.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.019229524665328693, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.2991, \"times_seen\": 11.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": -0.005874502287143567, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.004255552377342496, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -0.1736, \"times_seen\": 6.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.018334118384319566, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.1345, \"times_seen\": 9.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.005504590245745908, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -0.5846, \"times_seen\": 24.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"Q\", \"escape\": -0.0033950496637912696, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -1.3962, \"times_seen\": 8.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.015659599332664673, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.0468, \"times_seen\": 8.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.014710065660241791, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.1355, \"times_seen\": 22.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.008781355862724776, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.131, \"times_seen\": 8.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.026101496480265246, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.3085, \"times_seen\": 33.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.7900709495357204, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.1257, \"times_seen\": 32.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.024053498535909542, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.6738, \"times_seen\": 12.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.018471577121734185, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.1322, \"times_seen\": 2.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.04966633767308729, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.061, \"times_seen\": 66.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": -0.008469636021403545, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.1988, \"times_seen\": 9.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.16752293524424167, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1452, \"times_seen\": 116.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -2.066577055932676, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.341, \"times_seen\": 33.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.06002993957325992, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0714, \"times_seen\": 117.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -0.022338903999035067, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.3468, \"times_seen\": 31.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.029612440574849682, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.6219, \"times_seen\": 142.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.07297418798508937, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.01, \"times_seen\": 58.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.005122040805044945, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0112, \"times_seen\": 26.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -0.4174218400127572, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1797, \"times_seen\": 42.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": -0.1545111979641242, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0491, \"times_seen\": 98.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": 0.6508174347865154, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.1434, \"times_seen\": 45.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.055108839346806986, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1217, \"times_seen\": 91.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": -0.0063115077882420255, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -1.156, \"times_seen\": 43.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.08621658128483671, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.0172, \"times_seen\": 49.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.3778563228033517, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0486, \"times_seen\": 120.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.42495044297473683, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1925, \"times_seen\": 109.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -2.27580160749089, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0011, \"times_seen\": 93.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.18981986423514915, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.0316, \"times_seen\": 120.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.06872198509094134, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.2886, \"times_seen\": 56.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.04801799259571046, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1037, \"times_seen\": 108.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": -0.0005727410968644069, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.01214056828847438, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.3931, \"times_seen\": 11.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.002447045037082084, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.2537, \"times_seen\": 3.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": -0.013284317669224976, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.1902, \"times_seen\": 13.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.007220739922826026, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.0403, \"times_seen\": 3.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.0019683923934559113, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.3646, \"times_seen\": 19.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.012748840584446888, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.085, \"times_seen\": 4.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.006322492603652287, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -0.2643, \"times_seen\": 16.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.020207600757583564, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -0.4609, \"times_seen\": 19.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.3688001599394861, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -0.4381, \"times_seen\": 7.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.06801365555525261, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -2.0938, \"times_seen\": 1.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.00559247307715922, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -2.6479, \"times_seen\": 1.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.004206533481344426, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -1.144, \"times_seen\": 6.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.06878985976465912, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.1087, \"times_seen\": 165.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.053197584393335565, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.6542, \"times_seen\": 61.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.04703113154270269, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.4094, \"times_seen\": 72.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.062370949381972234, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.0374, \"times_seen\": 62.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.02079623002942051, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.7198, \"times_seen\": 99.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.18261447849399465, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.0382, \"times_seen\": 62.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": -0.040299626565052205, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.4664, \"times_seen\": 49.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.9136572064242343, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.3065, \"times_seen\": 47.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.013889142721191976, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.2325, \"times_seen\": 27.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.1758157095032064, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.6924, \"times_seen\": 140.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.03207049538549557, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.2322, \"times_seen\": 26.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.08366774559041608, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.309, \"times_seen\": 69.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.01109866144734461, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.9366, \"times_seen\": 51.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.006934006247993249, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.0502, \"times_seen\": 36.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.21846165932910552, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.2679, \"times_seen\": 76.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.052768679869389205, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.5069, \"times_seen\": 140.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 0.029568622922814397, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.5598, \"times_seen\": 83.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.03400159565222948, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.3738, \"times_seen\": 21.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -1.3837883000181368, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.7689, \"times_seen\": 137.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": 2.370238137241943, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -2.8311, \"times_seen\": 10.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.025155345559632527, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.3529, \"times_seen\": 33.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.02518150413617836, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.5469, \"times_seen\": 40.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.00826166033584931, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.1498, \"times_seen\": 9.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.011245324898631753, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.7398, \"times_seen\": 4.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.09527238013203793, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.0335, \"times_seen\": 57.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.03123993332113458, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": 0.0747, \"times_seen\": 21.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.015138746840971959, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.1382, \"times_seen\": 7.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.008121111529804704, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": 0.0508, \"times_seen\": 32.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.008632720483382853, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.64, \"times_seen\": 20.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.036050072375397015, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -0.4902, \"times_seen\": 24.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.002532671116421255, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -0.3262, \"times_seen\": 14.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 1.0873885820857143, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -1.7567, \"times_seen\": 19.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.007395452054138038, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -2.3738, \"times_seen\": 20.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.09315333475897009, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.0207, \"times_seen\": 41.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.038562105074062755, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.1825, \"times_seen\": 21.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.06528637352642307, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.2632, \"times_seen\": 63.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.8576581911500379, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": 0.00745363124119609, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.3737, \"times_seen\": 9.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.04791589124301174, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": -0.0503, \"times_seen\": 23.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.066063537824343, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.1371, \"times_seen\": 73.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.031802606429767906, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.0072, \"times_seen\": 28.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.5775288331356337, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.1717, \"times_seen\": 54.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.1319874991119754, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0675, \"times_seen\": 45.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -0.3695323857719693, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.3598, \"times_seen\": 41.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.026259266932415183, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0001, \"times_seen\": 11.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.08682501898869638, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.2112, \"times_seen\": 46.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.2825840468179914, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1457, \"times_seen\": 72.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": -0.007881644366530877, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0644, \"times_seen\": 24.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.02099058127414622, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.2432, \"times_seen\": 31.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.07354049209696553, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.2043, \"times_seen\": 20.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.0635156014980369, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.1505, \"times_seen\": 68.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.01289528455274763, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1411, \"times_seen\": 28.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.03134886948366555, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.3343, \"times_seen\": 42.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.07755401426745019, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.4107, \"times_seen\": 73.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.004544652153825997, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1028, \"times_seen\": 3.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.04479270794891748, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.2136, \"times_seen\": 59.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.05419337618570189, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1314, \"times_seen\": 36.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.1529613764378784, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.2812, \"times_seen\": 64.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 0.004527050934408149, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.363, \"times_seen\": 7.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.08337375803456484, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.2419, \"times_seen\": 46.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": -0.02383573293504293, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -2.1849, \"times_seen\": 4.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.008773764329495861, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -0.1909, \"times_seen\": 6.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.008427190303188635, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -1.4308, \"times_seen\": 5.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.00589247217853001, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.015399449854841724, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.3315, \"times_seen\": 20.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.047868510905788364, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.25, \"times_seen\": 24.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.10355363380817197, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.1042, \"times_seen\": 23.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": 0.02224588458580131, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -0.2985, \"times_seen\": 1.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": 0.011207747713100532, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.2514, \"times_seen\": 9.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.01936153750738812, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -1.0993, \"times_seen\": 8.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.0011798014527749463, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.5101, \"times_seen\": 4.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.026611506575404106, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.0568, \"times_seen\": 4.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.01911591474100602, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -2.7921, \"times_seen\": 17.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0032426888799502247, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -1.8188, \"times_seen\": 1.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.00030668292684210254, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -2.9466, \"times_seen\": 1.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.009552401695381362, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -1.3313, \"times_seen\": 11.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": -0.0016428041466231113, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.1611, \"times_seen\": 6.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.000995021188226815, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.1081, \"times_seen\": 1.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.004207160655897774, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.3291, \"times_seen\": 14.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.5916499749002296, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.1577, \"times_seen\": 4.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.015736937104544196, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.2621, \"times_seen\": 77.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0067965475702046335, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.3216, \"times_seen\": 10.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.01697900388910517, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.0948, \"times_seen\": 21.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.49177007804787454, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.2133, \"times_seen\": 5.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": 0.011513072003843943, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.4021, \"times_seen\": 2.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.007848313407795788, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.25, \"times_seen\": 21.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": 0.06486302753025856, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.7046, \"times_seen\": 7.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.01450690617335721, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": -0.3957, \"times_seen\": 12.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": 0.002822394757420147, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": -1.64, \"times_seen\": 1.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.01454338318366952, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.013986338182669169, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": -0.2645, \"times_seen\": 10.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.6598765488544988, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.3292, \"times_seen\": 4.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.012828738395974003, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -2.9634, \"times_seen\": 5.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.0028809933890884963, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -2.0743, \"times_seen\": 1.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.05227069498632059, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -0.1733, \"times_seen\": 27.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.006369743565182581, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.00304004148749208, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -3.126, \"times_seen\": 1.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.001885913646527846, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": 0.096, \"times_seen\": 4.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.023540082604227564, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -0.6883, \"times_seen\": 15.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.0077033952148401925, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -1.4144, \"times_seen\": 2.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.2092146100989539, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -1.6677, \"times_seen\": 18.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.09691419338698601, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.3039, \"times_seen\": 49.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.0040361394482585035, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.4446, \"times_seen\": 10.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.16868872279647742, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.2797, \"times_seen\": 66.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -0.05269861598672635, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.3733, \"times_seen\": 19.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.07824778940432471, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.6903, \"times_seen\": 71.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -1.733414922484569, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.6543, \"times_seen\": 18.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.010163179768220806, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.0843, \"times_seen\": 26.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -0.9789148240132898, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.4556, \"times_seen\": 23.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.23569041156156653, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.9281, \"times_seen\": 29.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.03596193850044618, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.2803, \"times_seen\": 12.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.01852752928447655, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.1851, \"times_seen\": 47.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": 0.014447501809112782, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -2.5739, \"times_seen\": 3.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.07299041426456433, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.3614, \"times_seen\": 24.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -1.5572131391449688, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.5694, \"times_seen\": 43.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.5284529186554374, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.507, \"times_seen\": 63.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.008538965532540313, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.3584, \"times_seen\": 23.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.003500102928366, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.9083, \"times_seen\": 32.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.05326422554638509, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.3042, \"times_seen\": 22.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.005106734527536933, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.1047, \"times_seen\": 20.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": -0.005500661733500743, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -2.9788, \"times_seen\": 3.0}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.003417992786824192, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -1.763, \"times_seen\": 1.0}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0027681447348240607, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -1.4484, \"times_seen\": 3.0}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.004553423672955321, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -1.2045, \"times_seen\": 17.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.005409955563865669, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.0805, \"times_seen\": 6.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": 0.011101897255489043, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -2.3314, \"times_seen\": 3.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.009530451755180896, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.4429, \"times_seen\": 18.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"H\", \"escape\": -0.011530453558146319, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.7319, \"times_seen\": 3.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.15380151772679346, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -0.0287, \"times_seen\": 24.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.01132960404929828, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.4796, \"times_seen\": 5.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.019230326586049413, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.1134, \"times_seen\": 8.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.006292158108604326, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.002873233686392468, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.9502, \"times_seen\": 6.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": 0.033150610572148236, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.8839, \"times_seen\": 3.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.02565121623109595, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.5432, \"times_seen\": 24.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.5163792899512248, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.1638, \"times_seen\": 18.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"A\", \"escape\": -0.2980618339139372, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.354, \"times_seen\": 80.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"C\", \"escape\": -0.42025033442359766, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -0.3075, \"times_seen\": 63.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": -0.03980872151015825, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.054, \"times_seen\": 79.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"E\", \"escape\": 0.5010515554209448, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1434, \"times_seen\": 34.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"F\", \"escape\": -0.1301123700427871, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.0385, \"times_seen\": 58.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"G\", \"escape\": 0.030032626003170606, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -0.1723, \"times_seen\": 66.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"I\", \"escape\": 0.4005674018269281, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.2681, \"times_seen\": 37.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"K\", \"escape\": 0.009012127129578178, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.2298, \"times_seen\": 59.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": -0.0002368356501201213, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1357, \"times_seen\": 179.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"M\", \"escape\": -0.06251827018344998, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3673, \"times_seen\": 35.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.08563380489103184, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1962, \"times_seen\": 63.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"P\", \"escape\": 0.019844828984137537, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -2.4186, \"times_seen\": 16.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": 0.06745288589451534, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3579, \"times_seen\": 114.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.005568668042880328, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.2391, \"times_seen\": 181.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": 0.2387507591596258, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.157, \"times_seen\": 161.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"T\", \"escape\": 0.008163682461591649, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3262, \"times_seen\": 66.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"V\", \"escape\": -0.3772864569045089, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3553, \"times_seen\": 113.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"W\", \"escape\": -0.01925133998102846, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1018, \"times_seen\": 29.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.04208480245633126, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.0851, \"times_seen\": 67.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"*\", \"escape\": -0.025667202789747785, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -2.3194, \"times_seen\": 8.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"-\", \"escape\": -0.0034313787731617864, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -0.8217, \"times_seen\": 1.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.010059038713294222, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -2.0274, \"times_seen\": 13.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": -0.04259674051155785, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -1.5595, \"times_seen\": 9.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.0033649453749002, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -0.2737, \"times_seen\": 12.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.04283072963190804, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.0006275930032523825, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -0.1368, \"times_seen\": 1.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.008869403133485243, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -1.2581, \"times_seen\": 5.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.01711319159559652, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.3312, \"times_seen\": 8.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": 0.0035127923429301927, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.1056, \"times_seen\": 10.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.01872187278229472, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.9177, \"times_seen\": 9.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.004784548965534776, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.1719, \"times_seen\": 16.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.014895250252422549, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.122, \"times_seen\": 17.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.013737945095531699, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": 0.3986, \"times_seen\": 8.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.08953173008269208, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.0619, \"times_seen\": 32.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.04530536197889115, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.0952, \"times_seen\": 27.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.017336852092197885, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.5593, \"times_seen\": 17.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.10852374518707418, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.2516, \"times_seen\": 77.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.04044796645255922, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.003025385527071303, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -0.3862, \"times_seen\": 1.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.06833882978145794, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -0.9988, \"times_seen\": 9.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": 0.018687028108597754, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -1.2735, \"times_seen\": 3.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.006297124434089461, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -0.54, \"times_seen\": 39.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.009606744669552995, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -1.6606, \"times_seen\": 13.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.013121106166401776, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -2.7862, \"times_seen\": 5.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.9125090614221618, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -0.2794, \"times_seen\": 2.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.008558516103682875, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -2.7605, \"times_seen\": 2.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.008883993922962454, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -1.3264, \"times_seen\": 1.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.011364565220922438, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -0.2295, \"times_seen\": 1.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.007554309511105027, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -1.2439, \"times_seen\": 1.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": -0.06550748545142253, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -2.1038, \"times_seen\": 6.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": -1.0639298109280175, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.1938, \"times_seen\": 9.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.026490011677846835, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.0033059931025912846, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.9805, \"times_seen\": 1.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.02409730586480688, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.3297, \"times_seen\": 11.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.02016328647086439, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.0866, \"times_seen\": 21.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.023516231652340926, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.2975, \"times_seen\": 11.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.007840785389908483, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -1.2786, \"times_seen\": 1.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.05554781522259219, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.4658, \"times_seen\": 43.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.06770043408359905, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.425, \"times_seen\": 4.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": -0.036572560248197244, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.2616, \"times_seen\": 24.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -1.4636589837494343, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": 0.2815, \"times_seen\": 5.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": -0.029785404409042582, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.9293, \"times_seen\": 10.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.016752028817071465, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.2061, \"times_seen\": 27.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.005635818602337924, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.8737, \"times_seen\": 2.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.012220229292415381, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.8218, \"times_seen\": 2.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.006807720138024599, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.7538, \"times_seen\": 3.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": 0.011788115182743098, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.7581, \"times_seen\": 3.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.0030931679147167, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.0019524716918263808, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.0048426958720160515, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -2.5528, \"times_seen\": 3.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.07684677945366104, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.3528, \"times_seen\": 30.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.01613954478420901, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.5852, \"times_seen\": 26.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.021362229755354564, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.4396, \"times_seen\": 31.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.002815102920595504, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -4.701277251581424e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.1421, \"times_seen\": 1.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.015358505121995238, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.1207, \"times_seen\": 3.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.027036925548438045, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.0698, \"times_seen\": 13.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.02844645886793806, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": 0.0106, \"times_seen\": 11.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.00048082481610385537, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.07481974662546777, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.0124, \"times_seen\": 20.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.03752227281965923, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.1502, \"times_seen\": 22.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": -0.00195975399681538, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.0759781239373344, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.4059, \"times_seen\": 30.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": -0.016510257065995553, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.3547, \"times_seen\": 12.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.003212560247387304, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -2.2174, \"times_seen\": 1.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.008549102690148093, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -2.4019, \"times_seen\": 2.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"-\", \"escape\": -0.0028399185276094955, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 963, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.0021004376585107643, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.019183844546551372, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.1633, \"times_seen\": 4.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.0018959011625384022, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -1.6437, \"times_seen\": 1.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.01468851521455336, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.3437, \"times_seen\": 5.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.022043918316080918, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -2.0275, \"times_seen\": 10.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.011292436374152573, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -1.1687, \"times_seen\": 4.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.0021422182027164977, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.681, \"times_seen\": 24.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.0055133058329815176, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -2.4424, \"times_seen\": 3.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.0036877853808730656, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -2.1403, \"times_seen\": 1.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.0022201834232092616, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.024902503997876458, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.6781, \"times_seen\": 52.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -1.3507428441530598, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": 0.3242, \"times_seen\": 8.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.017309255747000138, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -1.0771, \"times_seen\": 10.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.01785797078560546, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.0723, \"times_seen\": 4.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.014771789868189899, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": 0.3441, \"times_seen\": 23.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.0046720667087444415, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -2.4785, \"times_seen\": 3.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.019242502394403182, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -1.1234, \"times_seen\": 5.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.05947072659734679, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.0446, \"times_seen\": 21.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.009566962285878338, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.0248, \"times_seen\": 19.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.004889583175955576, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": 0.003464273208514153, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": 0.026353917368943672, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -1.6117, \"times_seen\": 17.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": -0.002048572385751616, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.037784515807287665, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.5324, \"times_seen\": 9.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": -0.006858236402069346, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.4857, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.014477104024448323, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.262, \"times_seen\": 12.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.015635100447142614, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.3963, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.043595877871056454, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.8676, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.004042903199977925, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.2689, \"times_seen\": 10.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.011647778564425016, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.9869, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.12433190417450464, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -1.4827, \"times_seen\": 55.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": -0.3402770851655717, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -1.4039, \"times_seen\": 28.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.006360518158768164, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.3216, \"times_seen\": 24.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.28990213261370007, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": 0.1338, \"times_seen\": 167.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": 0.1443590327002545, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -0.5279, \"times_seen\": 99.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.05302829895795273, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": 0.1531, \"times_seen\": 71.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": 0.00868373511321359, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.642, \"times_seen\": 5.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": 0.005599259461772501, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.8316, \"times_seen\": 6.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": -0.004053733989047484, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": 0.023429695200352332, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.7391, \"times_seen\": 2.0}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.01094134226000624, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -2.9828, \"times_seen\": 1.0}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.0058306041039551774, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0005825196751311225, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -0.7589, \"times_seen\": 1.0}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": -0.005840094341815185, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -3.0212, \"times_seen\": 1.0}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.012549964536307495, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -1.9913, \"times_seen\": 4.0}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.01429224344001496, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.7955, \"times_seen\": 5.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.03682573406241956, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -0.2237, \"times_seen\": 20.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": 0.006359920483417513, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.2134, \"times_seen\": 5.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.040574642247645724, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.0949, \"times_seen\": 17.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.0165135557640617, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -1.7998, \"times_seen\": 9.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.013458014294504522, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.9983, \"times_seen\": 5.0}, {\"site\": 970, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.010350041822065947, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -1.6201, \"times_seen\": 9.0}, {\"site\": 970, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.019983235561757903, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -0.172, \"times_seen\": 5.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.0006202343346240055, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.9803, \"times_seen\": 1.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.003190707027538814, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -0.3972, \"times_seen\": 2.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.0020204906816040087, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": 0.0648, \"times_seen\": 1.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.0034982482444214425, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.1772, \"times_seen\": 1.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.003741239095296764, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": 0.191, \"times_seen\": 2.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.005004614099225005, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -0.7476, \"times_seen\": 1.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.008081396952343748, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.6768, \"times_seen\": 3.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.02138822224009465, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": 0.4086, \"times_seen\": 21.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.007495137774565622, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -0.1918, \"times_seen\": 6.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.018968000301255984, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.952, \"times_seen\": 4.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.003378794771347997, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.3569, \"times_seen\": 1.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.013500323787497203, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": 0.309, \"times_seen\": 27.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.020946627228635935, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": 0.0741, \"times_seen\": 4.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.10452704489567805, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.2778, \"times_seen\": 40.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.03955123314968731, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.3156, \"times_seen\": 25.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.020907596010978646, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.3747, \"times_seen\": 18.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.010743944147403286, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.9486, \"times_seen\": 4.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.068428769308576, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.3943, \"times_seen\": 19.0}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.0030287119819358286, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": 0.0639, \"times_seen\": 6.0}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.03206241573461642, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -2.6936, \"times_seen\": 14.0}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.007735091659791435, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -2.8464, \"times_seen\": 2.0}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.03970894723167949, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": -0.017136376262010453, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.7606, \"times_seen\": 8.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.008913649179666193, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.2445, \"times_seen\": 3.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.0027167539451251935, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": 0.0876, \"times_seen\": 16.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.0035552541237234866, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -2.0323, \"times_seen\": 1.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.0035883601225791734, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": 0.2967, \"times_seen\": 7.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.012115018243545583, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -2.5281, \"times_seen\": 3.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.014577366116282874, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -2.4352, \"times_seen\": 2.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.003275127691123203, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -0.0933, \"times_seen\": 1.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.014766616571825498, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -2.3506, \"times_seen\": 5.0}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.00655320828516711, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -2.741, \"times_seen\": 2.0}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.03756764781271061, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -1.4023, \"times_seen\": 3.0}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.010524072009218781, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -1.8607, \"times_seen\": 3.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"A\", \"escape\": -0.3218008819681713, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.1042, \"times_seen\": 108.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.06881933779866918, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.1214, \"times_seen\": 69.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"D\", \"escape\": -0.5733993877311307, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -1.0959, \"times_seen\": 48.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"E\", \"escape\": -0.05210047364013932, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4195, \"times_seen\": 50.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"G\", \"escape\": -0.02804162505803548, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -1.8415, \"times_seen\": 45.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"H\", \"escape\": 0.02272318444991427, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.8577, \"times_seen\": 43.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.507907808138298, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4444, \"times_seen\": 120.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"K\", \"escape\": 0.07402462036742088, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.1794, \"times_seen\": 22.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.07340779523839283, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.2322, \"times_seen\": 117.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"M\", \"escape\": -0.04047567882191012, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.1087, \"times_seen\": 37.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"N\", \"escape\": -0.044489859060447806, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.4181, \"times_seen\": 48.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"P\", \"escape\": 0.24543269003355103, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.6849, \"times_seen\": 38.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"Q\", \"escape\": -0.013424988229554053, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.5073, \"times_seen\": 24.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"R\", \"escape\": -0.015500209545723276, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.2984, \"times_seen\": 48.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.1323608455433923, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4298, \"times_seen\": 154.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"T\", \"escape\": -0.057745249319821876, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4444, \"times_seen\": 89.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.5257448826258911, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4444, \"times_seen\": 124.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"W\", \"escape\": 0.15750009916205196, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.3058, \"times_seen\": 44.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.3656630834906079, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.3651, \"times_seen\": 89.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"*\", \"escape\": -0.0076950273698608565, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.6138, \"times_seen\": 4.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.3966085402072645, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": 0.2506, \"times_seen\": 109.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.021476731006806374, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.437, \"times_seen\": 54.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.0011731707931152495, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.5303, \"times_seen\": 31.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -1.1755555841812044, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.2212, \"times_seen\": 23.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.02307512408178994, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.1923, \"times_seen\": 12.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.10695904589887799, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.4425, \"times_seen\": 126.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.012309939630255682, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.3799, \"times_seen\": 16.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.358563152482477, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.0113, \"times_seen\": 44.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -0.048404371453726704, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.4314, \"times_seen\": 6.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.03050834231995279, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.0381, \"times_seen\": 68.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.017680927878962638, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.3015, \"times_seen\": 32.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.1895329746866331, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.2317, \"times_seen\": 79.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.13314558435250246, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.592, \"times_seen\": 72.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.005191406922959962, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.6221, \"times_seen\": 29.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.05208620046920961, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.7336, \"times_seen\": 29.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.025665218480146735, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.4339, \"times_seen\": 74.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 0.015924113586793805, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.4688, \"times_seen\": 63.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.012385905144416483, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.9806, \"times_seen\": 18.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.03141452277637251, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.5874, \"times_seen\": 20.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": 0.0192365788198127, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.4364, \"times_seen\": 3.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.015760079829340693, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -1.4676, \"times_seen\": 5.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.5571073284231908, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -1.359, \"times_seen\": 21.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.007219599646445555, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.8738, \"times_seen\": 3.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": -0.006408605932867168, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.0455, \"times_seen\": 8.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.007271246063550612, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -3.1267, \"times_seen\": 1.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.05734870837897475, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": 0.0263, \"times_seen\": 15.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.003421754795323792, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -1.2901, \"times_seen\": 1.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.021416599501258064, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -0.1847, \"times_seen\": 8.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.021406025051551387, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -2.9773, \"times_seen\": 5.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.001232836587707192, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -2.6755, \"times_seen\": 1.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0056747596488996525, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -2.6018, \"times_seen\": 2.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.017356708660126483, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -1.3383, \"times_seen\": 2.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.05580137458908285, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -1.3752, \"times_seen\": 16.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.0168957470451833, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.6096, \"times_seen\": 6.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.008359872716828918, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.8612, \"times_seen\": 1.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.004032899581074267, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -1.5046, \"times_seen\": 1.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -1.7208447261649125, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.1631, \"times_seen\": 39.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.5774638250467766, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.6573, \"times_seen\": 31.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.004373609014918543, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -3.054, \"times_seen\": 1.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.0043891571806052255, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.7122, \"times_seen\": 3.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.032740027298826406, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.7656, \"times_seen\": 1.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.018794173125613475, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.0602, \"times_seen\": 4.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.8327573925727426, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.3265, \"times_seen\": 26.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 1.1874688851177226, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -2.5728, \"times_seen\": 12.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.06835033552104408, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.5062, \"times_seen\": 26.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.0664676250394664, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.1729, \"times_seen\": 92.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.014616158986758176, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": 0.0755, \"times_seen\": 12.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.008681083125577728, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -0.0256, \"times_seen\": 38.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.018013888154291533, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.0631, \"times_seen\": 1.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -8.600056239623316e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -0.6662, \"times_seen\": 13.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.013929670172361219, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.2332, \"times_seen\": 10.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.0022483415596327083, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -0.1031, \"times_seen\": 7.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.014471800364678109, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": 0.1539, \"times_seen\": 8.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.042269396520533575, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.0405, \"times_seen\": 23.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.5903805348786199, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -0.9251, \"times_seen\": 45.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"L\", \"escape\": -0.032752081160908886, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.4406, \"times_seen\": 15.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -0.0016160148432637466, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -0.801, \"times_seen\": 21.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.0022102703173676394, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.4355, \"times_seen\": 5.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": -0.01131580181498729, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.014, \"times_seen\": 4.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.00011834715705025934, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -1.1198, \"times_seen\": 1.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": -0.00044519499945940325, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -3.2259, \"times_seen\": 1.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.558391144463785, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -1.5174, \"times_seen\": 19.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.0018511850436072619, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.7458, \"times_seen\": 2.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.004111483595889119, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.5217, \"times_seen\": 13.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.021633946849981236, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.3188, \"times_seen\": 8.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.029220184073948514, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.3632, \"times_seen\": 20.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.10629149297163808, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -0.5187, \"times_seen\": 43.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.11621182470258642, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -1.9929, \"times_seen\": 37.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"N\", \"escape\": -0.03429425727627761, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.2422500051103613, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.3215, \"times_seen\": 30.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.0021009108809146226, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -1.6432, \"times_seen\": 5.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.006774585053125243, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -1.6111, \"times_seen\": 3.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.014717920574846983, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -2.2801, \"times_seen\": 7.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": -0.0002796541153689174, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -0.113, \"times_seen\": 2.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.07231578584079132, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -0.6941, \"times_seen\": 22.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.054939454695217854, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -0.3699, \"times_seen\": 12.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.008303557393970195, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -1.7365, \"times_seen\": 2.0}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.025088938792944295, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.004946749133615435, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -2.8081, \"times_seen\": 1.0}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.017209936057157378, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -1.6191, \"times_seen\": 1.0}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.0016025489050896546, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -2.3991, \"times_seen\": 2.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.007490396097121708, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": -0.2947, \"times_seen\": 8.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.003724479612728813, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": -1.1686, \"times_seen\": 1.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 5.049784470573047e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": 0.3956, \"times_seen\": 1.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.026046350105807085, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": 0.2884, \"times_seen\": 22.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.018938723334827635, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.5788, \"times_seen\": 4.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": 0.018471822334044912, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.2389, \"times_seen\": 9.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.10995759113612341, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.566, \"times_seen\": 8.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.014978715909530076, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.6505, \"times_seen\": 5.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.0020190766777071433, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.8487, \"times_seen\": 1.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.003762306715705283, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.973, \"times_seen\": 9.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": -0.02560410666365759, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.282, \"times_seen\": 8.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.005619214521354751, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.4317, \"times_seen\": 2.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.008388850886998915, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.8796, \"times_seen\": 20.0}, {\"site\": 993, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.016141379948108853, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.7368, \"times_seen\": 6.0}, {\"site\": 993, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.005505152829144414, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.6411, \"times_seen\": 2.0}, {\"site\": 994, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.002718621439986986, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -2.9663, \"times_seen\": 1.0}, {\"site\": 994, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.007019997786503061, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -0.4513, \"times_seen\": 6.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.01250442185615053, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -0.2182, \"times_seen\": 5.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.012107241372041996, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -0.5475, \"times_seen\": 4.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.3805384914646287, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -0.1864, \"times_seen\": 58.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.0025709952419480002, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -2.9961, \"times_seen\": 5.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.022719963019619642, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": 0.2187, \"times_seen\": 8.0}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.004168376418616764, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.0619, \"times_seen\": 16.0}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.027488092617730893, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.9368, \"times_seen\": 14.0}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.011180010361379066, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -1.7115, \"times_seen\": 14.0}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.005787440374681672, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.3977, \"times_seen\": 1.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": 0.00021480486585478956, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.1814, \"times_seen\": 1.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": -0.005444814641216054, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.3084, \"times_seen\": 3.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.008260331951724556, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.6788, \"times_seen\": 2.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.057933773975581776, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.9436, \"times_seen\": 3.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.001063938884550912, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.8379, \"times_seen\": 1.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.001279538420734145, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.4962, \"times_seen\": 7.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.0008792987666043743, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.0806, \"times_seen\": 1.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.007348292151708812, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": 0.0572, \"times_seen\": 4.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.04214783505529052, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.5626, \"times_seen\": 3.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.601550277424212, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.0474, \"times_seen\": 4.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.013274101475519882, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -1.1479, \"times_seen\": 8.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"A\", \"escape\": 0.012325671502506704, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -1.4619, \"times_seen\": 2.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.010560304042564356, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": 0.3082, \"times_seen\": 11.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.007563203897254043, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -0.8236, \"times_seen\": 20.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.1400381281766796, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.6935, \"times_seen\": 14.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.039878604201872274, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.3498, \"times_seen\": 12.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.005277425707091276, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.6958, \"times_seen\": 3.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.034267476685654906, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -2.9328, \"times_seen\": 2.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.029693774997305168, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -0.1891, \"times_seen\": 13.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.33387140714016406, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": 0.4444, \"times_seen\": 28.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.001482848986944509, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -1.803, \"times_seen\": 1.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.01034906600868785, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -0.0835, \"times_seen\": 20.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.006119379614640885, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -0.1014, \"times_seen\": 2.0}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.00542839018880586, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.8704, \"times_seen\": 3.0}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0050195305241608435, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.08991575764845039, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.6499, \"times_seen\": 2.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.005872882386152115, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -0.8476, \"times_seen\": 62.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.01590227350082788, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -2.1267, \"times_seen\": 11.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 0.0031254710690247134, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -1.2242, \"times_seen\": 20.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -3.46435693485094e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -2.6955, \"times_seen\": 15.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.0033809142088317735, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -2.2327, \"times_seen\": 1.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.03764855590599045, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -0.0438, \"times_seen\": 21.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -1.2460913154003173, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -1.2634, \"times_seen\": 46.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.020312912860512372, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -2.1087, \"times_seen\": 5.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.01580177551581968, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": 0.2832, \"times_seen\": 3.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.005931978807457075, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": 0.1799, \"times_seen\": 29.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.026604571078898104, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -0.6323, \"times_seen\": 11.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.01072483030833669, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -2.9151, \"times_seen\": 4.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.007918023379209565, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -2.7839, \"times_seen\": 4.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.00348817777657071, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -2.6162, \"times_seen\": 1.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -0.003722349232924865, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -1.62, \"times_seen\": 1.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.009087497124191742, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -1.0404, \"times_seen\": 11.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.43621517741305427, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -1.0029, \"times_seen\": 11.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.010443647749353914, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -1.1313, \"times_seen\": 6.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": 0.0009203247262296484, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -2.9835, \"times_seen\": 1.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.043712588479020945, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -2.336, \"times_seen\": 6.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": 0.015432810423594573, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -1.0774, \"times_seen\": 19.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.004605300884869006, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -0.1907, \"times_seen\": 75.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.004936126859916479, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -3.0194, \"times_seen\": 1.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.6694535851334932, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -1.5244, \"times_seen\": 21.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.03034532259892436, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -2.2375, \"times_seen\": 7.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.022549884265121497, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.0605, \"times_seen\": 26.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.01269561174948929, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.3591, \"times_seen\": 8.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"M\", \"escape\": 0.057732150854149275, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.2318, \"times_seen\": 19.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": -0.005551197045457366, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.1312, \"times_seen\": 38.0}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.17668378124291434, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.0277, \"times_seen\": 29.0}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.04036575707954326, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -1.6652, \"times_seen\": 15.0}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.0155567574668073, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.8592, \"times_seen\": 25.0}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.01271709305020518, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.8773, \"times_seen\": 4.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.02876468530836981, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -0.9178, \"times_seen\": 13.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.005515601123485382, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -0.3205, \"times_seen\": 2.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.12005060209026384, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -2.4375, \"times_seen\": 5.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.00555435831559635, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.0171863348204251, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.011798684441674843, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -0.6953, \"times_seen\": 7.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.0001759777284031742, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -0.9232, \"times_seen\": 2.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.038106607424893676, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -2.0467, \"times_seen\": 12.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 1.2491276302285312, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -1.7187, \"times_seen\": 17.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.003079384544578211, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -1.9471, \"times_seen\": 1.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.04393241214577047, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -2.111, \"times_seen\": 4.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.10701928543085051, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -1.1865, \"times_seen\": 41.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.007253092753975267, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.8212, \"times_seen\": 18.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.014233641120061145, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": 0.4444, \"times_seen\": 71.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.006263942129234595, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.7817, \"times_seen\": 13.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": -0.011043568749073064, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.9301, \"times_seen\": 7.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.0010009990979525502, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.6521, \"times_seen\": 19.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.07755475117592989, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.1905, \"times_seen\": 38.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.00640843442295481, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.8081, \"times_seen\": 3.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.021319154785146673, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -3.0886, \"times_seen\": 2.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": -0.016238286238621693, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -2.2673, \"times_seen\": 5.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.015464545019647963, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -0.2662, \"times_seen\": 34.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.0009108294897955968, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -2.0108, \"times_seen\": 7.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.014987091352278006, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -2.7786, \"times_seen\": 5.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": 0.0026975745575856915, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -1.9172, \"times_seen\": 1.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.011373108782163075, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -0.5694, \"times_seen\": 4.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.015924614106783152, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -0.1187, \"times_seen\": 11.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.10715114552323485, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.1466, \"times_seen\": 56.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.11402645423612193, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.4444, \"times_seen\": 145.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.030770298525783717, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.3904, \"times_seen\": 64.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.17848013153219386, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.3865, \"times_seen\": 15.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.028954093063344306, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.2148, \"times_seen\": 5.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.1496086994493397, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.3651, \"times_seen\": 40.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.0049919777139460966, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.004937989180922991, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.3501, \"times_seen\": 1.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.04417516207244269, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -1.9964, \"times_seen\": 16.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0657696363504301, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -1.319, \"times_seen\": 22.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.058082534714021784, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -0.0369, \"times_seen\": 50.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.006278010741078788, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0030015014760232123, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -1.1885, \"times_seen\": 1.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.26684488193659567, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -0.4457, \"times_seen\": 81.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.010699051552441762, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -2.4929, \"times_seen\": 1.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -1.7239564314466054, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -1.5594, \"times_seen\": 21.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.0066084504103273425, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -0.6401, \"times_seen\": 29.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.013183326894247562, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -2.7786, \"times_seen\": 3.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"Q\", \"escape\": -0.02058374000865004, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -1.9902, \"times_seen\": 4.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.023710839512215046, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -1.9743, \"times_seen\": 1.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.007540736819431304, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6982, \"times_seen\": 17.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.05671913169776279, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.958, \"times_seen\": 28.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.021531952766572826, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -1.0272, \"times_seen\": 40.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.1849821108720313, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.2906, \"times_seen\": 12.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.039602733311689606, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.8455, \"times_seen\": 81.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.0276315897237627, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -1.6341, \"times_seen\": 13.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.012165962950404674, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6665, \"times_seen\": 6.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -1.8458862374112555, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -1.8672, \"times_seen\": 18.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.033377092687395964, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -2.4464, \"times_seen\": 14.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.019184730617495142, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.9902, \"times_seen\": 15.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.02650537794100399, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6127, \"times_seen\": 11.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.005286558605198339, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -2.7603, \"times_seen\": 5.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.48668066173078106, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.7244, \"times_seen\": 22.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.06066699748762194, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.4314, \"times_seen\": 74.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.37498639449576926, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.2797, \"times_seen\": 111.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.24938873707013431, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.3397, \"times_seen\": 101.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.19810906264792857, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6024, \"times_seen\": 127.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"W\", \"escape\": -0.005101526034824687, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.2591, \"times_seen\": 19.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.03141493956052671, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.4778, \"times_seen\": 10.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.004389883366493728, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -2.9948, \"times_seen\": 1.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.005357284368315525, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.9083, \"times_seen\": 1.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.03143497610095389, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.8606, \"times_seen\": 10.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.1575123803438212, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.9573, \"times_seen\": 27.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.009825765002534705, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.9223, \"times_seen\": 7.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.04666128707132542, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.5607, \"times_seen\": 20.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.018650426977752547, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.8753, \"times_seen\": 1.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.015162297357400066, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.4657, \"times_seen\": 6.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.00876004263043581, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.9181, \"times_seen\": 1.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.01596898480424039, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -0.8362, \"times_seen\": 34.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.008061639636703304, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.3735, \"times_seen\": 9.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.021910516139696214, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.7325, \"times_seen\": 2.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.02845624924466339, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": -1.4309, \"times_seen\": 27.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.015155808733353376, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.1589, \"times_seen\": 29.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.00023223515939983905, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.9197946814112306, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.0756, \"times_seen\": 79.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": -0.12381629238516115, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.4444, \"times_seen\": 16.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.12377752033066569, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": -0.5625, \"times_seen\": 83.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.12937725300551284, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.031, \"times_seen\": 63.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.3247874807814415, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.3044, \"times_seen\": 54.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.016744531527260655, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -2.1134, \"times_seen\": 8.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.011842665932825779, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -1.4723, \"times_seen\": 25.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.010323427891251616, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -1.4396, \"times_seen\": 23.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.010550270896782085, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -2.4232, \"times_seen\": 1.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.0009140105179267895, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -1.5057, \"times_seen\": 1.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0749141028309037, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -0.5949, \"times_seen\": 24.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.0025364178258707485, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -2.3092, \"times_seen\": 1.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.015694975541882088, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -0.9721, \"times_seen\": 11.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.01751842734709027, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.9406, \"times_seen\": 1.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.006844478127072605, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.8946, \"times_seen\": 2.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.006936842296524673, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.7023, \"times_seen\": 8.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.00735546007560882, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -0.3951, \"times_seen\": 1.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.009384686939714953, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.9787, \"times_seen\": 2.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.011656997306020312, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -0.2546, \"times_seen\": 19.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.009787476208393374, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -1.8377, \"times_seen\": 25.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.4939588346009596, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.9637, \"times_seen\": 6.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.06734396441996278, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.9119, \"times_seen\": 85.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.04465929203216543, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.6409, \"times_seen\": 34.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.0842634036876906, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.5114, \"times_seen\": 35.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": -0.03539661115252584, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.0087, \"times_seen\": 33.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.49678856804238336, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8598, \"times_seen\": 48.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": -0.060423785105240505, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.9465, \"times_seen\": 35.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.08749543542576255, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8568, \"times_seen\": 38.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.7788721725299921, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.4041, \"times_seen\": 54.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.008551598754673966, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.8558, \"times_seen\": 10.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.1490426379223217, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.0517, \"times_seen\": 144.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": -0.02003468788864707, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.425, \"times_seen\": 43.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.260140192108321, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.7085, \"times_seen\": 58.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.0031301251621794015, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.5785, \"times_seen\": 10.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.007568675240282635, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.04284854208697923, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8558, \"times_seen\": 117.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -1.4495755187463937, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8175, \"times_seen\": 180.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.018139968000134097, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.3363, \"times_seen\": 33.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": 0.007288740075668756, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.0872, \"times_seen\": 8.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": 0.0025855774500960662, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.6245, \"times_seen\": 12.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": -0.0158176427953356, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.9022, \"times_seen\": 5.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.0132200571714227, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -0.1676, \"times_seen\": 1.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.7773134723172377, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -2.9637, \"times_seen\": 4.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.02062552018474342, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -2.6429, \"times_seen\": 4.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.023520793401651603, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -2.3767, \"times_seen\": 6.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"C\", \"escape\": -0.00942251469945727, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.451, \"times_seen\": 1.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -1.0913530891460888, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -1.349, \"times_seen\": 47.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.0007060989714070099, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.596, \"times_seen\": 2.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"R\", \"escape\": -0.008210478208841394, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.2197, \"times_seen\": 1.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.009367018235618082, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.5108, \"times_seen\": 1.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": 0.02619893780034998, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -1.3142, \"times_seen\": 25.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0013424270930207122, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -0.1609, \"times_seen\": 17.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.029888087139011716, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.5245, \"times_seen\": 4.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.04730732240046264, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.9561, \"times_seen\": 3.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.0006152590133503493, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.4774, \"times_seen\": 1.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.0014184092036208062, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.6183, \"times_seen\": 1.0}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.7753747248963173, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9297, \"times_seen\": 11.0}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": 0.014043067667104924, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.8256, \"times_seen\": 1.0}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": 0.013358603718795064, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.7814, \"times_seen\": 1.0}, {\"site\": 1029, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": 0.029785343695708903, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9152, \"times_seen\": 1.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.015772996101150613, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -1.4429, \"times_seen\": 9.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.00539197727988978, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.6888, \"times_seen\": 1.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.006767864135812136, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.434, \"times_seen\": 2.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.0012764316851338804, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.0594, \"times_seen\": 1.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.007126674436256929, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.5961, \"times_seen\": 2.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -2.7432309783925612, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -1.0692, \"times_seen\": 6.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.004821357953266681, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -1.2398, \"times_seen\": 15.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.031948831192449775, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": 0.3887, \"times_seen\": 4.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.002415635953544106, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": 0.3651, \"times_seen\": 30.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.016362968825727936, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -0.9591, \"times_seen\": 1.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.01090529073523492, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.6997, \"times_seen\": 3.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0008281585159820979, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.4806, \"times_seen\": 1.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.010365323614056841, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.7178, \"times_seen\": 5.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.01726592219758197, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.6825, \"times_seen\": 7.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.006134348909109376, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.465, \"times_seen\": 5.0}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": -0.010424948869866406, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -2.558, \"times_seen\": 5.0}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.003414099454003318, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -2.933, \"times_seen\": 1.0}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": -0.00736026555169268, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -2.6751, \"times_seen\": 1.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.005830762622366986, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -0.7186, \"times_seen\": 1.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.01854416713552796, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -1.4326, \"times_seen\": 2.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.004368233114338678, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.7668, \"times_seen\": 6.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.0064660681304335235, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.3881, \"times_seen\": 2.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.03936301117329648, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -0.5421, \"times_seen\": 18.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.002921593890302934, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.4226, \"times_seen\": 1.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.012032274940966812, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -1.0333, \"times_seen\": 27.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": 0.0010411477162940485, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -1.7715, \"times_seen\": 1.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.06480203240310092, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.3826, \"times_seen\": 14.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.8690129226330315, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.3265, \"times_seen\": 20.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.0007018182740606279, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.0722, \"times_seen\": 25.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.1667344050314668, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.2803, \"times_seen\": 49.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.022705490213088222, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.1467, \"times_seen\": 12.0}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"E\", \"escape\": -0.0033908667370689217, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -3.0763, \"times_seen\": 1.0}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": 0.0008806405654627977, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.479, \"times_seen\": 2.0}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.0023656400161485946, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.9133, \"times_seen\": 1.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.045903363560332276, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": 0.0238, \"times_seen\": 22.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.07206395518642869, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -0.9927, \"times_seen\": 22.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.026536406056333478, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -2.6141, \"times_seen\": 2.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.015098687122349084, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -2.0361, \"times_seen\": 5.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.018540593438505313, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -2.0321, \"times_seen\": 9.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.03203702256763506, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -0.3684, \"times_seen\": 22.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.006404284436627747, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.3271, \"times_seen\": 16.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.02633839396021772, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.9511, \"times_seen\": 126.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.0010656325268657636, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -2.4891, \"times_seen\": 1.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.0197755631633569, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -2.072, \"times_seen\": 29.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.018462507579471866, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.8159, \"times_seen\": 1.0}, {\"site\": 1039, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.01943934446051386, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -0.7176, \"times_seen\": 16.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.0034021779416941356, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.6105, \"times_seen\": 3.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.007111626199102939, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -1.6803, \"times_seen\": 6.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.002698356710995033, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -1.0532, \"times_seen\": 1.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": 0.02413560087460387, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.4504, \"times_seen\": 5.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.0019521236705336827, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.8414, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.009561730192702893, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -1.4106, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.8627656326895848, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.8731, \"times_seen\": 4.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.010300029580953851, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.2404, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.0175364619288278, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.9256, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.02849813436958887, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.7309, \"times_seen\": 8.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.04036393162487674, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.8822, \"times_seen\": 23.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.038087909570465504, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -2.2214, \"times_seen\": 10.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.1155740463477922, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.1793, \"times_seen\": 26.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.14831076449019365, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.018, \"times_seen\": 15.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.030079507956258224, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": 0.1656, \"times_seen\": 52.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.05031924118431909, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.3548, \"times_seen\": 10.0}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.04151037087865697, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -1.1822, \"times_seen\": 12.0}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.8805883336727149, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -2.8615, \"times_seen\": 4.0}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.019087849168952335, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -1.7674, \"times_seen\": 7.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.03463450115439984, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.5979, \"times_seen\": 5.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.05399891238350375, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.3915, \"times_seen\": 11.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.012466850758621995, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.6773, \"times_seen\": 5.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.04512957163076067, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -0.3012, \"times_seen\": 10.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": -0.005860864296659474, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -3.0069, \"times_seen\": 1.0}, {\"site\": 1045, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": -0.003372521356855801, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.1124, \"times_seen\": 1.0}, {\"site\": 1045, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.002902015369119916, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.0457, \"times_seen\": 1.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.005875439854441618, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.8127, \"times_seen\": 2.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.008474251113674431, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.1582, \"times_seen\": 13.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.004011585536456624, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.3985, \"times_seen\": 1.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.0033413198399719853, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.9313, \"times_seen\": 1.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.003886585984175389, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.4874, \"times_seen\": 2.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.006088201039074676, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.5783, \"times_seen\": 6.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -0.06922495629707712, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -0.8474, \"times_seen\": 91.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.012817028824645162, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -0.1566, \"times_seen\": 32.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": 0.011403520913442855, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -2.1339, \"times_seen\": 7.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": -1.418033550317198, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -1.9149, \"times_seen\": 19.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"Y\", \"escape\": -0.01985603700427862, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -2.3353, \"times_seen\": 2.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.01903215166566918, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.1776, \"times_seen\": 2.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.002291481542687829, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.77, \"times_seen\": 1.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.006349859609849109, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.9548, \"times_seen\": 2.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.0028246273894931054, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.9464, \"times_seen\": 1.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.0027592705013062785, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 0.0022958225596768226, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.7313, \"times_seen\": 1.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": 0.01289029055492683, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -2.9498, \"times_seen\": 1.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.01844703404848496, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -2.9411, \"times_seen\": 5.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.001502580751628391, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -1.1545, \"times_seen\": 22.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.003753440403685641, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -0.6482, \"times_seen\": 1.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.009895384362796883, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.04255463424810502, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -1.0543, \"times_seen\": 29.0}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": 3.450362557780515, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -3.0239, \"times_seen\": 4.0}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.11153522096577778, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.2702, \"times_seen\": 1.0}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": 0.09431422184437817, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.4716, \"times_seen\": 2.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.037329114690442027, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -0.0857, \"times_seen\": 16.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.0018581953294709457, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.9005, \"times_seen\": 1.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.01605750093536993, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.8457, \"times_seen\": 2.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.055249179873203526, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -2.3702, \"times_seen\": 11.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.004046902747590131, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -2.4943, \"times_seen\": 1.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.00020811975092780682, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.7888, \"times_seen\": 9.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.022680678173308124, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.1067, \"times_seen\": 10.0}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.011913720907597736, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -2.8479, \"times_seen\": 1.0}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.0016174904413019716, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -2.9022, \"times_seen\": 3.0}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.724659267458881, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -1.5274, \"times_seen\": 41.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.002861838654227869, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.98, \"times_seen\": 1.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.12398273474707917, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.7923, \"times_seen\": 6.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.006159668138795392, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.7854, \"times_seen\": 2.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.034042430490065466, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -0.7767, \"times_seen\": 1.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.0007252096445874418, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.3737, \"times_seen\": 8.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.01635976042365963, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.3326, \"times_seen\": 21.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.046430799244464645, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.5183, \"times_seen\": 61.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"S\", \"escape\": 0.012719190809973647, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.5405, \"times_seen\": 16.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.08368494383590445, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -1.0804, \"times_seen\": 52.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.014419778722879834, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.5641, \"times_seen\": 5.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.007292809966526451, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.5162, \"times_seen\": 6.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.05065649979382984, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.4709, \"times_seen\": 5.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.0029937634137871248, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.5775, \"times_seen\": 1.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": 0.004502765205538941, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.9473, \"times_seen\": 4.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.0003914785179253051, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.1962, \"times_seen\": 2.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.009558470308380427, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -0.8753, \"times_seen\": 11.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": 0.028061965193824315, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -0.6008, \"times_seen\": 15.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.007253150940073298, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -0.2763, \"times_seen\": 19.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 1.1943178610474559, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -2.1423, \"times_seen\": 20.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.008022618830504709, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -2.6312, \"times_seen\": 4.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.010805516576832028, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.4204, \"times_seen\": 10.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.009984320749859919, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.3203, \"times_seen\": 9.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.027777858647791594, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -1.0395, \"times_seen\": 12.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 9.127186936058633e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": 0.0117, \"times_seen\": 3.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.0012169612197414394, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.0322, \"times_seen\": 10.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": -0.016028173820579812, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -2.7374, \"times_seen\": 2.0}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.004246179949289022, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -2.5942, \"times_seen\": 1.0}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.530613386358323, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -1.2258, \"times_seen\": 14.0}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.004671439343706599, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -2.8525, \"times_seen\": 4.0}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.008420443044596472, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -0.6038, \"times_seen\": 2.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": 0.014854301050380431, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.513, \"times_seen\": 10.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": -0.009993715159718303, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5841, \"times_seen\": 9.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": 0.031195462394278027, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.738, \"times_seen\": 6.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": -0.014948067262185956, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.7019, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.02280380119684334, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -1.2671, \"times_seen\": 46.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": 0.0029749846934013034, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5585, \"times_seen\": 18.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.009857979651658967, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5981, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.039310658930305456, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -1.4099, \"times_seen\": 31.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.01321833816114091, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6852, \"times_seen\": 4.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.016149770789644368, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -0.7638, \"times_seen\": 22.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": -0.010010175311386427, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6918, \"times_seen\": 4.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.04274589313992661, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6696, \"times_seen\": 14.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.008066787787967326, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.8479, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.00786882164065485, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.7412, \"times_seen\": 16.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.028300136000568337, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5558, \"times_seen\": 15.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": 0.006037120294524442, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.7268, \"times_seen\": 7.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": 0.054587949457079975, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -1.8064, \"times_seen\": 58.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.024970629123452878, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.3231, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": 0.01648726168347604, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -3.0762, \"times_seen\": 3.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"*\", \"escape\": -0.006735023765972762, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6833, \"times_seen\": 3.0}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"A\", \"escape\": 0.0018658218306456856, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -3.0111, \"times_seen\": 1.0}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": 0.040965043659272976, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.0417, \"times_seen\": 1.0}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.00517113816420716, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.1372, \"times_seen\": 3.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.05213990105580756, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -0.3229, \"times_seen\": 31.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": 0.004821193446091503, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": 0.125, \"times_seen\": 8.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.8421367810273441, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -0.6764, \"times_seen\": 90.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.5991581562227246, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": 0.4444, \"times_seen\": 47.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.04045455427919375, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -0.233, \"times_seen\": 22.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.08599015804537657, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -0.4897, \"times_seen\": 36.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.04968752283599297, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -1.4653, \"times_seen\": 29.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": 0.20681409110581397, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": 0.2891, \"times_seen\": 104.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": 0.06379854499397766, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -2.9958, \"times_seen\": 4.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.2262566474393714, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": 0.2725, \"times_seen\": 44.0}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -1.9210476767617182, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -0.8799, \"times_seen\": 37.0}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.048657074239411416, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -2.6468, \"times_seen\": 4.0}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.029562223602209066, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -2.9939, \"times_seen\": 2.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.004599861928711169, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.1319, \"times_seen\": 30.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": 0.11021215532587846, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.0246, \"times_seen\": 58.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": 0.013159910743860493, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.55, \"times_seen\": 13.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.0828249644763069, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.4462, \"times_seen\": 16.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.011504373737024258, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.9872, \"times_seen\": 26.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.9277653998255118, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.5016, \"times_seen\": 11.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"H\", \"escape\": -0.01899036108007339, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.3264, \"times_seen\": 15.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.06571077082283856, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.0789, \"times_seen\": 56.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"K\", \"escape\": 0.23885096332650224, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.1811, \"times_seen\": 21.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.0022392028815261737, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.6599, \"times_seen\": 122.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.01111290085734844, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.4082, \"times_seen\": 35.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"N\", \"escape\": 0.06671128040097571, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.7039, \"times_seen\": 10.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"P\", \"escape\": -0.008783619994256241, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.59, \"times_seen\": 11.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": 0.05966205086930652, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.6464, \"times_seen\": 33.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": 0.08341955588197143, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.9362, \"times_seen\": 64.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.0788214054395606, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.2309, \"times_seen\": 36.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": 0.01445634715983019, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.7788, \"times_seen\": 29.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"W\", \"escape\": -0.03328234742543076, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.3901, \"times_seen\": 8.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.004380027218478174, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.8595, \"times_seen\": 2.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"*\", \"escape\": -0.001995372637508428, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.4287, \"times_seen\": 6.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.01210053669217333, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.8035, \"times_seen\": 6.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.003950451831874146, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.9453, \"times_seen\": 2.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"M\", \"escape\": -0.001437018446000958, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.8659, \"times_seen\": 1.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.0332442394968102, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.1741, \"times_seen\": 32.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.006430210149339304, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -1.1377, \"times_seen\": 15.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.0036719931761580358, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -0.5238, \"times_seen\": 12.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.0032586921221294963, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -2.3483, \"times_seen\": 2.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.03531298703977889, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.2697, \"times_seen\": 23.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.01183389007786208, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -0.4643, \"times_seen\": 34.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"M\", \"escape\": -0.020456990380277627, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.3362, \"times_seen\": 11.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.031913447113016975, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -0.3005, \"times_seen\": 52.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.028690955270081395, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.4444, \"times_seen\": 97.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.027194310844976564, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.1886, \"times_seen\": 52.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"-\", \"escape\": 0.021044008772453552, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.014053203264376833, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.506, \"times_seen\": 24.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.0006549908402707523, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -1.27, \"times_seen\": 45.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.06831998637181587, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.0109, \"times_seen\": 25.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.2928131477072383, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.5261, \"times_seen\": 77.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": 0.5003534467588325, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.2455, \"times_seen\": 77.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": 0.09426182185530908, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -1.2601, \"times_seen\": 9.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"-\", \"escape\": 0.022214059724405353, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.030602779243489094, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": 0.4134, \"times_seen\": 9.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.02695558594212331, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.3371, \"times_seen\": 21.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.023599556356124558, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.4297, \"times_seen\": 3.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"H\", \"escape\": 0.007289268192321523, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -0.3225, \"times_seen\": 1.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.0981669764541997, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.5922, \"times_seen\": 52.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.25427100670320457, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": 0.1158, \"times_seen\": 50.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -1.3944661968781258, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -2.3716, \"times_seen\": 9.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -3.1943401061998093, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.6824, \"times_seen\": 20.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.02054305813201042, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.382, \"times_seen\": 3.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.008575123903318806, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.3758, \"times_seen\": 54.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.004807421302577914, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.4496, \"times_seen\": 15.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.5733666805632786, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.0038, \"times_seen\": 87.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.05223340029478023, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.4858, \"times_seen\": 39.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.012377396282462939, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.013, \"times_seen\": 25.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.1676445175437587, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": 0.0736, \"times_seen\": 112.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.048432674039543856, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.6264, \"times_seen\": 50.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.03894019359104063, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.441, \"times_seen\": 70.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"E\", \"escape\": -0.007550317370662908, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.3182, \"times_seen\": 11.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.02978270359545294, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.6686, \"times_seen\": 22.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.014846060520561285, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.3058, \"times_seen\": 42.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.015288857719568406, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.648, \"times_seen\": 52.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.00021181485194073443, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.4069, \"times_seen\": 65.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.031006808123824947, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.3442, \"times_seen\": 23.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.0025517571012907687, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -1.2563, \"times_seen\": 20.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.05164124936560956, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": 0.1042, \"times_seen\": 27.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.00570547960495834, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -2.9691, \"times_seen\": 1.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": -0.049680391103396206, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -1.3245, \"times_seen\": 29.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.03881986022092992, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -0.1886, \"times_seen\": 34.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.019558001502790582, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -1.4501, \"times_seen\": 19.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.044886341708842994, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -1.2811, \"times_seen\": 10.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.09415640656419937, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": 0.0389, \"times_seen\": 76.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": -0.00425273812626885, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -0.1396, \"times_seen\": 2.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.0077163245480182064, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -1.4546, \"times_seen\": 2.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.007100912162673483, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -0.921, \"times_seen\": 66.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.05660342305786565, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": 0.1939, \"times_seen\": 53.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.014856956109568616, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.176, \"times_seen\": 3.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.006033770094429904, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -1.5999, \"times_seen\": 8.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.01536904162771057, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -0.8197, \"times_seen\": 14.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.09848528623492672, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.5227, \"times_seen\": 7.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.011705845635692835, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.7531, \"times_seen\": 20.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.010923553054030926, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.0754, \"times_seen\": 3.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": -0.007407848046037493, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.0433, \"times_seen\": 2.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"F\", \"escape\": -0.007085908161372758, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.4729, \"times_seen\": 8.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"G\", \"escape\": -0.031228848898859476, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.6183, \"times_seen\": 53.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"H\", \"escape\": -0.014287281936790137, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.7754, \"times_seen\": 6.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"I\", \"escape\": -0.007023935678076129, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -1.9792, \"times_seen\": 3.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"K\", \"escape\": -0.009695291337776316, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.0339, \"times_seen\": 2.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": -0.01255998107657812, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.9199, \"times_seen\": 5.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"N\", \"escape\": -0.010111833965022778, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.7906, \"times_seen\": 3.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.006571547240217344, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.6398, \"times_seen\": 1.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"Q\", \"escape\": 0.03738941196555589, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.6828, \"times_seen\": 2.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"R\", \"escape\": -0.05199423453142711, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.0061, \"times_seen\": 8.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -1.3917915812847743, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.437, \"times_seen\": 72.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.832351568378538, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.7051, \"times_seen\": 96.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.011832800013596783, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.1939, \"times_seen\": 28.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"Y\", \"escape\": -0.010060815698041, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.8147, \"times_seen\": 3.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"*\", \"escape\": -0.0038622738989607915, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.010281612502559795, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -1.5482, \"times_seen\": 3.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.0035784794187829643, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.020285593049340696, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -0.5505, \"times_seen\": 19.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.0053345159099092545, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": 0.2181, \"times_seen\": 44.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": 0.03970399140807844, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -2.3128, \"times_seen\": 1.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"C\", \"escape\": 0.0013482793912971333, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -1.1145, \"times_seen\": 5.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.012408790919600185, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -0.4165, \"times_seen\": 27.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.008034717273463617, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -2.092, \"times_seen\": 11.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.0026549915232326306, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -2.1791, \"times_seen\": 5.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.17690006491180252, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.4039, \"times_seen\": 57.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"H\", \"escape\": 0.028970448087867584, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -2.9388, \"times_seen\": 5.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.023894389782248338, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.7406, \"times_seen\": 7.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.020221528906097706, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.0659, \"times_seen\": 23.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.019491330856064474, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -1.4291, \"times_seen\": 10.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.00315708788463842, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.3121, \"times_seen\": 30.0}, {\"site\": 1079, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.016404718150860663, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.469, \"times_seen\": 3.0}, {\"site\": 1079, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.0081107386241285, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.5589, \"times_seen\": 2.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": 0.011101708024514403, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.003, \"times_seen\": 6.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": 0.0017748128082291346, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.7085, \"times_seen\": 4.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -0.00015804134889063263, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.1981, \"times_seen\": 2.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": 0.0484481292254491, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.163, \"times_seen\": 9.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.002246893635468277, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.2165, \"times_seen\": 5.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.038625311557678885, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.1137, \"times_seen\": 25.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.01898346387452083, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.0057, \"times_seen\": 18.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -1.3234911448883373, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": 0.2472, \"times_seen\": 6.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.0643829225450776, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": 0.2612, \"times_seen\": 17.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.010908828462782974, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.2983, \"times_seen\": 8.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.001997928795576695, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.239, \"times_seen\": 3.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.01874585212372801, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.0323, \"times_seen\": 25.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.0035695638562254148, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -1.0749, \"times_seen\": 1.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.043530269460631335, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.1623, \"times_seen\": 48.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.056342878424839406, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -0.0241, \"times_seen\": 28.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": 0.008489120337985542, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -0.1119, \"times_seen\": 5.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.0014706703066394646, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.1736, \"times_seen\": 15.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.009254110178827846, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -0.1385, \"times_seen\": 21.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.014107756452717928, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -2.2934, \"times_seen\": 4.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.027456382207745395, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.3973, \"times_seen\": 24.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.008892393985924273, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.2824, \"times_seen\": 6.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": -0.018601256011126926, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.5523, \"times_seen\": 8.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.03155257537924029, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.7429, \"times_seen\": 15.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.006185965808550302, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.4261, \"times_seen\": 13.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.011270667838340732, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": 0.1127, \"times_seen\": 52.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.0033573473576579997, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.0806, \"times_seen\": 2.0}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.01917098781189241, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": 0.0105, \"times_seen\": 13.0}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.12074426549010088, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.0232, \"times_seen\": 20.0}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": -0.0006708659134420526, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.8206, \"times_seen\": 15.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": 0.002865598775061399, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -1.4304, \"times_seen\": 1.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": 0.00385716351405278, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -0.7507, \"times_seen\": 7.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": 0.2041299835819524, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -0.1165, \"times_seen\": 7.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"T\", \"escape\": -0.021290004381019478, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -0.3033, \"times_seen\": 8.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": 0.015076912464266599, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": 0.2076, \"times_seen\": 64.0}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.0047718834466970415, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -1.8346, \"times_seen\": 2.0}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.007961438491520844, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -1.3854, \"times_seen\": 3.0}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.029795891177204156, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": 0.394, \"times_seen\": 21.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": -0.010105526480377802, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -0.1195, \"times_seen\": 2.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.02504263025660879, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -1.4863, \"times_seen\": 9.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.017719709067187738, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -2.0288, \"times_seen\": 1.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.12466359860180384, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -0.3631, \"times_seen\": 33.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.017057873659201334, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -0.4244, \"times_seen\": 1.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.013132436402083645, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -1.6448, \"times_seen\": 7.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.00014618033578600822, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -0.0665, \"times_seen\": 38.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"H\", \"escape\": -0.007927013992919936, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -0.3618, \"times_seen\": 5.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.8602383064330394, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.3108, \"times_seen\": 21.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": 0.014828122984987847, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -1.0451, \"times_seen\": 5.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": -0.00598969185504656, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -1.0036, \"times_seen\": 4.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": 0.026120852488165314, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.2589, \"times_seen\": 12.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.010656141545863678, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.010098961748418227, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -0.5347, \"times_seen\": 8.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.05156629204039548, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": 0.2621, \"times_seen\": 25.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.0010580541319269972, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -1.3051, \"times_seen\": 24.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.003396667000630129, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -1.5301, \"times_seen\": 32.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.020738318653153294, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -0.7884, \"times_seen\": 17.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.02127812621756729, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -0.9278, \"times_seen\": 13.0}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.02494458542165411, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -2.5162, \"times_seen\": 2.0}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.8831060800513834, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -0.8766, \"times_seen\": 26.0}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.01465684606665747, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -1.0177, \"times_seen\": 5.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.02531855497443182, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -1.5209, \"times_seen\": 12.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.010856283529401786, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": 0.223, \"times_seen\": 24.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.02548585109224706, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -1.4895, \"times_seen\": 9.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.009147682044969819, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -2.3822, \"times_seen\": 5.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.02286265539098781, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -1.3913, \"times_seen\": 6.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.01176492246548868, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -0.105, \"times_seen\": 6.0}, {\"site\": 1092, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.033152805102731345, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -0.5826, \"times_seen\": 35.0}, {\"site\": 1092, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": 0.6930435435121896, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -0.2225, \"times_seen\": 25.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.041873057949328565, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": 0.3309, \"times_seen\": 13.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.01580842304856249, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -2.2618, \"times_seen\": 1.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.018094457903192217, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -2.2925, \"times_seen\": 2.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.01694558108084404, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": 0.3568, \"times_seen\": 79.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.08576705461196919, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -0.4912, \"times_seen\": 22.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.023030695254266743, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -0.7564, \"times_seen\": 35.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.01768650254274631, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -0.3257, \"times_seen\": 15.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.05244065692106147, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.020695357489449676, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.0757, \"times_seen\": 17.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.0027387148049587786, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -1.405, \"times_seen\": 1.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.0068038169320183434, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -0.6398, \"times_seen\": 5.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.19433772708878447, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.4231, \"times_seen\": 71.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": -0.009101245928184615, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.158, \"times_seen\": 2.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.016525653373579717, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -2.1066, \"times_seen\": 8.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.003754937736780075, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.005217973668795172, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.5034, \"times_seen\": 14.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.003877104743698024, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.5287, \"times_seen\": 1.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.00910974025525143, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -1.0252, \"times_seen\": 3.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": -0.05843795427296637, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.536, \"times_seen\": 24.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.006247731182444471, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.0463, \"times_seen\": 12.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.00033228233323915067, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": 0.2974, \"times_seen\": 1.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.0011685978342933672, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.8839, \"times_seen\": 27.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.03798172814582631, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.263, \"times_seen\": 140.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.0182136052112155, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.1589, \"times_seen\": 6.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.01566963242508678, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.217, \"times_seen\": 72.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.0005817106330722287, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.2863, \"times_seen\": 13.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.010022815516649903, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.5929, \"times_seen\": 28.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.30576546961948814, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": -0.0827, \"times_seen\": 32.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.056885802226742666, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": -0.0143, \"times_seen\": 71.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.013717514552185202, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": 0.0987, \"times_seen\": 12.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.043810112279916984, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": 0.1204, \"times_seen\": 4.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.04343923304877097, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": -0.0231, \"times_seen\": 39.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"D\", \"escape\": 0.1762927093966252, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.0306, \"times_seen\": 83.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"E\", \"escape\": -0.012203302679859864, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1584, \"times_seen\": 19.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": -0.013857009556015614, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1489, \"times_seen\": 17.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": 0.00408994501888556, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.0334, \"times_seen\": 44.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": 0.37388009367970304, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1925, \"times_seen\": 83.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": 0.009314262418320408, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.0986, \"times_seen\": 24.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"T\", \"escape\": 0.0060259039777019, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1924, \"times_seen\": 1.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.04530465434433527, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.0633, \"times_seen\": 127.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.0036416381484986314, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.729, \"times_seen\": 6.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": -0.006042742612158024, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": 0.0646, \"times_seen\": 16.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": 0.04909395767526855, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -1.6568, \"times_seen\": 28.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"S\", \"escape\": 0.01802186648267949, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.9385, \"times_seen\": 2.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"T\", \"escape\": -0.012005544386038437, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.2473, \"times_seen\": 6.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": -0.009330968133387185, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -1.9349, \"times_seen\": 3.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.033546674548425456, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": -0.6281, \"times_seen\": 12.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.001498214241916109, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.0246, \"times_seen\": 1.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.01912811654430754, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": -0.1738, \"times_seen\": 52.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.022980527507054295, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.2814, \"times_seen\": 49.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.00897634794352769, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.4077, \"times_seen\": 5.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -1.0569101007578838, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -1.4398, \"times_seen\": 3.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 0.007977683622522899, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.0063, \"times_seen\": 5.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.2574934676181728, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.1818, \"times_seen\": 19.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0802028233457948, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.4747, \"times_seen\": 29.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.036744676609137696, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.0126, \"times_seen\": 8.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": 0.00021751982735954928, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -1.5585, \"times_seen\": 3.0}, {\"site\": 1102, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.0026396058615402985, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 1102, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.00010965822813185576, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -3.1318, \"times_seen\": 1.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.26318520174495297, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.739, \"times_seen\": 4.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.01690365548164913, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.4537, \"times_seen\": 8.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.008111116626768305, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.9677, \"times_seen\": 2.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"T\", \"escape\": -0.0039031136329135104, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.1603, \"times_seen\": 1.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.00538788829326714, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.9491, \"times_seen\": 1.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.036221796439857096, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.9585, \"times_seen\": 13.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.041295028808769424, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0633, \"times_seen\": 59.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.024206452040337157, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0679, \"times_seen\": 15.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"M\", \"escape\": 0.8275543732595738, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0667, \"times_seen\": 68.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": 0.054411449657635384, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.0549, \"times_seen\": 8.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.318140301524676, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.0861, \"times_seen\": 35.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.012885205245003792, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.7845, \"times_seen\": 5.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"W\", \"escape\": -0.0019011713509889258, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.3463, \"times_seen\": 1.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.00019329654503813282, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -0.8893, \"times_seen\": 8.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 1.2075681773539513, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": 0.0578, \"times_seen\": 22.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.006327119917340394, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": 0.1833, \"times_seen\": 2.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.004101770296282112, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -2.3399, \"times_seen\": 20.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 0.08242295619026378, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -2.3165, \"times_seen\": 10.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.008090154297591082, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -1.0527, \"times_seen\": 15.0}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.04485519121929399, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": -1.3553, \"times_seen\": 10.0}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.3694129987055757, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": -0.8859, \"times_seen\": 26.0}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.006455921159273424, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": 0.2652, \"times_seen\": 18.0}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.012541172772694042, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -2.561, \"times_seen\": 2.0}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.009559122112158225, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": 0.066, \"times_seen\": 30.0}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.07475139871817003, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -1.6806, \"times_seen\": 9.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.0014811796194544962, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.2492, \"times_seen\": 11.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.0019809172863517466, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.7751, \"times_seen\": 12.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.00818708912520498, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.3871, \"times_seen\": 9.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.14459682336814686, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.8824, \"times_seen\": 41.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.011596228988649758, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -0.0614, \"times_seen\": 12.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": 0.022465208306327346, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.9665, \"times_seen\": 4.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"T\", \"escape\": -0.0002508801815430625, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.4665, \"times_seen\": 2.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.00025348195989230785, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.7096, \"times_seen\": 1.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.01872219791302554, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -2.4076, \"times_seen\": 11.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.009262799681841715, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -0.7292, \"times_seen\": 43.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.11869092384472135, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -0.9911, \"times_seen\": 22.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.014433780095328839, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -1.7155, \"times_seen\": 10.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"V\", \"escape\": 0.027843948236328027, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -1.9212, \"times_seen\": 7.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.02595465772587633, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -0.8441, \"times_seen\": 15.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.013831779133190078, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.45391522012410046, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.3841, \"times_seen\": 26.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.48572947104737035, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.4138, \"times_seen\": 48.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"M\", \"escape\": 0.4786356236366354, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -0.2198, \"times_seen\": 13.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.05572318749497096, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": 0.005898460939711058, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -1.6966, \"times_seen\": 2.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.009750006105835422, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": -0.0523, \"times_seen\": 13.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.024636613412770094, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": -0.1349, \"times_seen\": 25.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.01991620091333263, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.00393361085733245, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.2317, \"times_seen\": 9.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.01265528326398752, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.059, \"times_seen\": 7.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.0020015626154316463, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.1919, \"times_seen\": 16.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -1.9282137908074195, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.1682, \"times_seen\": 31.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"C\", \"escape\": -0.014033031911020288, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.0514, \"times_seen\": 8.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.010085697459407055, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.0997, \"times_seen\": 11.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.022549583508709274, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.5368, \"times_seen\": 1.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.003876723848037275, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.4465, \"times_seen\": 1.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.04132800040214218, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.0783, \"times_seen\": 40.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.2858906000328879, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": 0.0418, \"times_seen\": 50.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.034751751262980864, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": 0.1899, \"times_seen\": 25.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.06736991839829586, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": -1.9701, \"times_seen\": 23.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.024071492105843348, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": -0.2024, \"times_seen\": 67.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -1.1691700185806184, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": 0.2663, \"times_seen\": 25.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.0510482371657561, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": -1.6437, \"times_seen\": 8.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.03889063099631347, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4808, \"times_seen\": 123.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"C\", \"escape\": -0.02408634600938392, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.3026, \"times_seen\": 56.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"D\", \"escape\": -0.0862682038645188, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.5538, \"times_seen\": 43.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"E\", \"escape\": 0.04263249078521788, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.3872, \"times_seen\": 45.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": -0.0018790960601275605, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.7441, \"times_seen\": 46.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"G\", \"escape\": 0.4138456913718893, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.8119, \"times_seen\": 122.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"H\", \"escape\": -0.047630105742886154, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -1.1124, \"times_seen\": 33.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.012987010455543676, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.0388, \"times_seen\": 86.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 1.1098584901941053, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.2293, \"times_seen\": 20.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"L\", \"escape\": 0.023634410978055517, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.0931, \"times_seen\": 127.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"M\", \"escape\": 0.0415534882620192, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.1527, \"times_seen\": 39.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.04661637199309468, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.1167, \"times_seen\": 48.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"P\", \"escape\": -0.06010403677344974, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.5241, \"times_seen\": 67.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": 0.047869568305007375, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4067, \"times_seen\": 42.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"R\", \"escape\": 0.08475070956653676, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.2972, \"times_seen\": 175.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.007122169009483989, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4777, \"times_seen\": 146.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"V\", \"escape\": -0.009724959089864864, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.284, \"times_seen\": 92.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"W\", \"escape\": -0.5618666532303106, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -1.7711, \"times_seen\": 18.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"Y\", \"escape\": 0.5215288744845596, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4969, \"times_seen\": 43.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"*\", \"escape\": 2.1783692173174654, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -2.7794, \"times_seen\": 7.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.24824063991695633, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -0.4849, \"times_seen\": 76.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": -0.0888428665396771, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -0.8215, \"times_seen\": 31.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -2.059194059801401, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.1149, \"times_seen\": 53.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": 0.050991559805676254, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.2446, \"times_seen\": 33.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.04889720616617307, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.0924, \"times_seen\": 95.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.781729373233899, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3279, \"times_seen\": 30.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.037132116533213765, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.4012, \"times_seen\": 24.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -0.013327092810368568, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -0.4248, \"times_seen\": 9.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": 0.3596674302695877, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.317, \"times_seen\": 73.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": 0.9305868512544808, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.2603, \"times_seen\": 28.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.0319643852300337, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": -0.37091636224693864, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -1.2134, \"times_seen\": 22.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": 0.0832319980009688, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3173, \"times_seen\": 19.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": 0.0013800330923204559, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.2213, \"times_seen\": 77.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.04883072806160149, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.0417, \"times_seen\": 71.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.0001690801807895708, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3475, \"times_seen\": 41.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.868854620144634, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3064, \"times_seen\": 92.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": -0.01771791771940773, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.4418798548848747, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3516, \"times_seen\": 54.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": -0.006801816961929826, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -2.9791, \"times_seen\": 2.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.006447506611007739, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -1.0119, \"times_seen\": 5.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.009483880360239184, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -0.995, \"times_seen\": 2.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.000657088711779773, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -2.0861, \"times_seen\": 2.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.010638229193146387, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -1.3586, \"times_seen\": 3.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": -0.01048757099531697, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -1.6105, \"times_seen\": 3.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.01393611267423748, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -0.8817, \"times_seen\": 3.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.051714710788339856, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -0.5789, \"times_seen\": 14.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"F\", \"escape\": 0.01739181962349057, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -1.8992, \"times_seen\": 1.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.0006553792246565108, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -1.2336, \"times_seen\": 19.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.001670389447754991, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -1.2726, \"times_seen\": 2.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": 0.024865637605178834, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -0.4278, \"times_seen\": 18.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.006266889869366117, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -1.7205, \"times_seen\": 2.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.005956796914965136, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -1.0324, \"times_seen\": 2.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": 0.008126854058668654, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -0.7748, \"times_seen\": 20.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"M\", \"escape\": -0.003649261292796057, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -0.6682, \"times_seen\": 1.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.016649499718660248, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -1.1454, \"times_seen\": 4.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0086684712662414, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": 0.4125, \"times_seen\": 4.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.017083930632941516, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": 0.0042, \"times_seen\": 2.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.2412841517461625, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.007962793650709288, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.4705, \"times_seen\": 2.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.026474933072322276, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.004, \"times_seen\": 13.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.017271367424696253, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.163, \"times_seen\": 23.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.02269917291379601, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.4456, \"times_seen\": 34.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.031585320851803704, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.1848, \"times_seen\": 20.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.02045274386376175, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": 0.2764, \"times_seen\": 11.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.007516843152771673, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -1.8543, \"times_seen\": 5.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.002022449477713848, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -3.0152, \"times_seen\": 1.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.03326974714457333, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -1.1837, \"times_seen\": 16.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.0022823763141761023, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -2.4402, \"times_seen\": 1.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.031785916674209456, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -0.0177, \"times_seen\": 17.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.011583452171872477, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -1.2961, \"times_seen\": 2.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.0518290941542917, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": 0.0116, \"times_seen\": 22.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.7790577376659563, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.3083, \"times_seen\": 52.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.16015001530626585, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.0186, \"times_seen\": 50.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.027071064007782447, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.2825, \"times_seen\": 17.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.0191188248882572, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": 0.1842, \"times_seen\": 71.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.008944195606407917, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.8127, \"times_seen\": 16.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.005294722588071828, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.5036, \"times_seen\": 57.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.8848860762407582, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.4432, \"times_seen\": 21.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.1990093238490058, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.393, \"times_seen\": 79.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.9193096087189544, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.5408, \"times_seen\": 19.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.6667029195941531, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -1.063, \"times_seen\": 19.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.013408922841612585, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -1.0489, \"times_seen\": 28.0}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.0010828564855503348, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -0.724, \"times_seen\": 1.0}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.046267772389992745, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.2172, \"times_seen\": 4.0}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.004130060969765261, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.8921, \"times_seen\": 1.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": 0.03595950969575562, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -0.1624, \"times_seen\": 11.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.05850633786192511, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.008, \"times_seen\": 34.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.07311516420270767, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.1577, \"times_seen\": 65.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.4419305428816511, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.02, \"times_seen\": 6.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.13755145278811015, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -0.24, \"times_seen\": 62.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.007976704845712598, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -1.2044, \"times_seen\": 17.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.05645815890312928, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -0.3369, \"times_seen\": 58.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.028972461600582998, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": -0.1722, \"times_seen\": 10.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.023398260877877476, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.2539, \"times_seen\": 37.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.09831746191067896, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.2408, \"times_seen\": 80.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.009690161234262062, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.3979, \"times_seen\": 29.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.02524035684010638, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.3325, \"times_seen\": 13.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 0.0037344058717882636, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -1.7693, \"times_seen\": 2.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.0459785317961673, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -0.1637, \"times_seen\": 40.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.0043914670529786905, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.1342, \"times_seen\": 13.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.9784518894469685, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.6109, \"times_seen\": 3.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.004079036429314055, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -0.7439, \"times_seen\": 25.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.5431398509353761, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -0.1114, \"times_seen\": 63.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.0076960248201317655, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.8813, \"times_seen\": 1.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.0026975773549938998, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.3624, \"times_seen\": 1.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.011650252403451723, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.3744, \"times_seen\": 21.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.6256232975397714, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.21, \"times_seen\": 45.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.1260450269576556, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -1.6676, \"times_seen\": 30.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.0076723904930492, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -0.4444, \"times_seen\": 26.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.0012879655152609431, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -1.1128, \"times_seen\": 15.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.003499535694704313, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -2.0817, \"times_seen\": 1.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.002614534913644992, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -1.5422, \"times_seen\": 2.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.02514238179325709, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.7658, \"times_seen\": 11.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.010045598877519749, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -0.4432, \"times_seen\": 16.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.002711261269359141, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.5141, \"times_seen\": 1.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.029140267519628768, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.5754, \"times_seen\": 10.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.11023869386243329, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.005, \"times_seen\": 27.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.02703090303919131, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.0239, \"times_seen\": 24.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.27397186884974134, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.8393, \"times_seen\": 37.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.0030515612500902115, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": 0.0819, \"times_seen\": 20.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.6690754139882243, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.4561, \"times_seen\": 48.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.023539521541226908, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.2285, \"times_seen\": 22.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.025779385255664377, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.1632, \"times_seen\": 23.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.023235012711709926, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.2539, \"times_seen\": 18.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.010947519543268431, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": -0.4037, \"times_seen\": 1.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.018247431075965468, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.3876, \"times_seen\": 8.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.020238315998112964, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.1915, \"times_seen\": 19.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.038519523179534415, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.0579, \"times_seen\": 26.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.06842243036612633, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": -0.2686, \"times_seen\": 54.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.009107279674371029, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.3392, \"times_seen\": 1.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.1799219436856367, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.3287, \"times_seen\": 47.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.09429332509633687, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.4444, \"times_seen\": 34.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.002836099980980951, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.1278, \"times_seen\": 29.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.0743616185117697, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.0169, \"times_seen\": 30.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.004691979365707533, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.4444, \"times_seen\": 40.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.04485817305715819, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.2773, \"times_seen\": 28.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.04072212926847911, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.3854, \"times_seen\": 73.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": -0.03421892749665661, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.1615, \"times_seen\": 30.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"Q\", \"escape\": -0.011093067985191218, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.1291, \"times_seen\": 23.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.09095725050355659, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.3655, \"times_seen\": 28.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.004359840490644391, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": -0.6368, \"times_seen\": 1.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.007810420928666494, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": -0.3921, \"times_seen\": 26.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.004215058101886753, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.07646560518562022, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": 0.1507, \"times_seen\": 32.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.020254178949267888, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": -0.5631, \"times_seen\": 11.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.04130059328456851, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -1.7593, \"times_seen\": 2.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": 0.03696647447758809, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -0.6748, \"times_seen\": 1.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.038217572321580094, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": 0.2701, \"times_seen\": 31.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.09782864489831106, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -0.3486, \"times_seen\": 28.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": -0.011797949739590948, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": 0.4337, \"times_seen\": 16.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.01766480623568252, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.913, \"times_seen\": 14.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -1.5506896690628809, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -2.1192, \"times_seen\": 15.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.024261940129950466, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.0282, \"times_seen\": 26.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.0911277909786551, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -0.2512, \"times_seen\": 63.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": 0.0037699554828929836, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.4491, \"times_seen\": 12.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.2461828609504367, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.3553, \"times_seen\": 87.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.0025550626517583156, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.6317, \"times_seen\": 9.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.014107361486819644, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.2, \"times_seen\": 60.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.020398270267416516, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.4051, \"times_seen\": 17.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.007473351345035443, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.4109, \"times_seen\": 3.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.016394081247379115, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.2334, \"times_seen\": 5.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.3078118482699639, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.397, \"times_seen\": 21.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.030602699028904883, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.3651, \"times_seen\": 9.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.0255680802257307, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.4315, \"times_seen\": 83.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.02215692576627001, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.169, \"times_seen\": 1.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.007478510154404933, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.965, \"times_seen\": 4.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.004827017602934704, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -2.5233, \"times_seen\": 2.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.00205820804355275, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.1736, \"times_seen\": 1.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.06033566733810635, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.6613, \"times_seen\": 17.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": -0.012557948392394574, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.1245, \"times_seen\": 20.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.007640571504684199, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -0.0954, \"times_seen\": 2.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -1.1085399981917239, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -0.777, \"times_seen\": 41.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"M\", \"escape\": 0.010052410837691891, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -0.888, \"times_seen\": 18.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.1589045948874922, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": 0.397, \"times_seen\": 20.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"*\", \"escape\": -0.011801238207227144, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -2.2672, \"times_seen\": 1.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.005549264252639781, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": -0.03968536851279706, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": 0.13134379431997156, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.394, \"times_seen\": 78.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.7220527681064207, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": 0.014525455876974564, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.03097454679619617, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.2804, \"times_seen\": 33.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.8591773967911619, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": -0.8182, \"times_seen\": 55.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.041428979590642956, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": -0.2457, \"times_seen\": 1.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.02196907879137436, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.4317, \"times_seen\": 107.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.46261658318497867, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.4266, \"times_seen\": 30.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": 0.030531482214763535, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.312, \"times_seen\": 20.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.019434214149856393, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.3085, \"times_seen\": 51.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.011759048071835778, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": -1.4739, \"times_seen\": 3.0}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.03215392850527947, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -0.6534, \"times_seen\": 6.0}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.007726218981600745, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -2.2462, \"times_seen\": 1.0}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.003423637106046731, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -1.3835, \"times_seen\": 2.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.026803296129920606, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": 0.0804, \"times_seen\": 16.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.04592663986922949, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.0953, \"times_seen\": 83.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 1.0949274790721786, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -1.1339, \"times_seen\": 18.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.04777298017305343, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.3235, \"times_seen\": 50.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": 0.051061579436725985, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.2148, \"times_seen\": 67.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.02968019765094211, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -1.1626, \"times_seen\": 49.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.03500651265074112, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": 0.4273, \"times_seen\": 22.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.006371978949110123, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -1.1498, \"times_seen\": 4.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.33136622926568166, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -0.5645, \"times_seen\": 34.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.04262523063485201, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -2.038, \"times_seen\": 9.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.01090512158207739, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -0.2766, \"times_seen\": 18.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.0013369207864340935, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -1.213, \"times_seen\": 3.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.00627952631118891, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -0.392, \"times_seen\": 3.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.028583652224977475, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -0.3991, \"times_seen\": 27.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.010992203374441312, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -0.2699, \"times_seen\": 2.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0047366207665657375, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": 0.1984, \"times_seen\": 1.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.008788168267797396, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -1.6481, \"times_seen\": 3.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.1436209900998439, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -0.5776, \"times_seen\": 78.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.025347248529549903, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -1.8489, \"times_seen\": 25.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": -0.003375051216908796, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -0.9531, \"times_seen\": 1.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.010514764246349883, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -0.0919, \"times_seen\": 57.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.002371344228983546, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -2.3638, \"times_seen\": 1.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.03879121185929991, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.4162, \"times_seen\": 9.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.2131958168600944, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.0334, \"times_seen\": 75.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.035794258255084296, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.078, \"times_seen\": 24.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.5903492649637301, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.2965, \"times_seen\": 54.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.01947626963748274, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.1427, \"times_seen\": 30.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.029780392619087367, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.6488, \"times_seen\": 29.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.00468620049637951, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -2.9546, \"times_seen\": 1.0}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": 0.14458872992309155, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": 0.3094, \"times_seen\": 55.0}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.011534313010295547, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": -0.8579, \"times_seen\": 46.0}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.010598607262234008, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": -0.3312, \"times_seen\": 6.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.01695512326157122, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -0.2535, \"times_seen\": 3.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0023568649515063786, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -0.1685, \"times_seen\": 5.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.008104407415841383, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -0.0935, \"times_seen\": 3.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.007311580227714301, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -2.4196, \"times_seen\": 2.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.12891255990041142, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": -0.2024, \"times_seen\": 36.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.006637691669298137, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.1902, \"times_seen\": 26.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.054536079434073514, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": -0.1208, \"times_seen\": 48.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.019434536779972655, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.2916, \"times_seen\": 58.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.005905852097160037, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.0225, \"times_seen\": 43.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.006134764212487646, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.1762, \"times_seen\": 1.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.0024428302526696114, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.4035, \"times_seen\": 12.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.27720430489628073, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.3282, \"times_seen\": 52.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.036202562629763964, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3145, \"times_seen\": 32.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.00011092458583514328, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.023232489897587586, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3651, \"times_seen\": 36.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.05607207526531725, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.2984, \"times_seen\": 29.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.023332158518229295, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3142, \"times_seen\": 15.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.003969623526699158, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.4344, \"times_seen\": 16.0}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.008584622599690696, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -1.3143, \"times_seen\": 3.0}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.038127897348165796, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -0.2061, \"times_seen\": 38.0}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.6401319916749019, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": 0.3612, \"times_seen\": 83.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"C\", \"escape\": -0.002348569501913762, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": -0.0038201478392488144, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -0.2959, \"times_seen\": 1.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.015700707086641327, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -0.3184, \"times_seen\": 47.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": 0.03472275181704037, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -0.0529, \"times_seen\": 2.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.0014394640452560473, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": 0.4067, \"times_seen\": 1.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.0004918547836427941, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3787, \"times_seen\": 43.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.09287188763353359, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3254, \"times_seen\": 78.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.1995641541654178, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3259, \"times_seen\": 79.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.05443435871371788, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3548, \"times_seen\": 54.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.0323845898254132, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.2959, \"times_seen\": 31.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.0676844130483641, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.6253, \"times_seen\": 28.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.238264811576401, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.0871, \"times_seen\": 31.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.011424135835583755, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.19513641263857073, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.656, \"times_seen\": 25.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.5740794105002781, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.6445, \"times_seen\": 85.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.007785507320941762, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.5265, \"times_seen\": 27.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.002763342424965897, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.2548, \"times_seen\": 19.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"L\", \"escape\": 0.38814840104855525, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": -0.3597, \"times_seen\": 28.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"N\", \"escape\": -0.10708544684534048, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.152, \"times_seen\": 18.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"Q\", \"escape\": 0.01918564307422953, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.2068, \"times_seen\": 24.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"R\", \"escape\": -1.9476456623507947, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.0721, \"times_seen\": 43.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"Y\", \"escape\": -0.15201508499662694, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.0425, \"times_seen\": 61.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.03478325228488693, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.78, \"times_seen\": 36.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": 0.005962262072766466, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.7148, \"times_seen\": 5.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -0.007274444684591861, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.2803, \"times_seen\": 8.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.0016171109704033332, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.1738, \"times_seen\": 2.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.39740430468455923, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.2119, \"times_seen\": 15.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.002105851551740619, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.1953, \"times_seen\": 1.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.0020529477726674854, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.0086, \"times_seen\": 5.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.009678068523468749, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.9118, \"times_seen\": 4.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 0.006798852370141853, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.2703, \"times_seen\": 9.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.0033686814317270305, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.0661, \"times_seen\": 17.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.008464718017903428, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.572, \"times_seen\": 8.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.01835677544927517, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.1152, \"times_seen\": 6.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"A\", \"escape\": 0.008341631035800457, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.0636, \"times_seen\": 33.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"H\", \"escape\": 0.011080464516018913, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.0107, \"times_seen\": 6.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.5298054487774644, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.1481, \"times_seen\": 35.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": 0.37655726856630706, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.0636, \"times_seen\": 43.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"R\", \"escape\": -0.2903188934922212, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.2868, \"times_seen\": 14.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": 0.07315529429762524, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.0167, \"times_seen\": 26.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.1352022949724158, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.0225, \"times_seen\": 52.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.922512394847194, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.1275, \"times_seen\": 192.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"C\", \"escape\": 0.017747541368567283, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -1.0516, \"times_seen\": 42.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.23828786668671714, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0843, \"times_seen\": 153.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"F\", \"escape\": -1.1394684795231549, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.7344, \"times_seen\": 46.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.07299077278435993, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0435, \"times_seen\": 209.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.011300554431836477, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.3688, \"times_seen\": 136.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"I\", \"escape\": -0.25156071380359063, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2986, \"times_seen\": 68.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"K\", \"escape\": -0.09179638375334168, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2916, \"times_seen\": 72.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"L\", \"escape\": -0.10102170790958684, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.4725, \"times_seen\": 103.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": -0.00921410080351379, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.3362, \"times_seen\": 38.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.018073085112268007, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.074, \"times_seen\": 180.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"P\", \"escape\": 0.3134841138481837, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0814, \"times_seen\": 112.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"Q\", \"escape\": -0.04667500081621128, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.204, \"times_seen\": 38.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"R\", \"escape\": -0.03323779203001447, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2112, \"times_seen\": 122.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": 0.019729212815125144, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0991, \"times_seen\": 157.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": 0.13918321464543626, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.1426, \"times_seen\": 99.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.2965415670285388, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2857, \"times_seen\": 123.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"W\", \"escape\": 0.10109548225423919, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.7356, \"times_seen\": 53.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.2121626356203815, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.5144, \"times_seen\": 141.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"*\", \"escape\": 0.057779006641997255, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -2.8361, \"times_seen\": 14.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": -0.0060959231144601935, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.00734303945024593, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.0882, \"times_seen\": 10.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.012227864324960829, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.2839, \"times_seen\": 2.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.02665601191512405, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.1568, \"times_seen\": 12.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.0446614178416253, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.149, \"times_seen\": 18.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.0014938336805185822, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.0091, \"times_seen\": 9.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.16247743600028935, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.0547, \"times_seen\": 14.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.005860283125658554, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.5365632142485569, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": 0.0419, \"times_seen\": 33.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.0007924029421676076, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.0693, \"times_seen\": 73.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.05334938801309461, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": 0.0946, \"times_seen\": 173.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.07297152238390855, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.0328, \"times_seen\": 21.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.052207457904522615, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.0022, \"times_seen\": 56.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.05658482567963847, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.4093, \"times_seen\": 31.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": 0.0009042001843372558, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.294, \"times_seen\": 17.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": -0.007565859913550477, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.007115873755476404, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": 0.0174, \"times_seen\": 7.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.001165235444384221, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": 0.0125, \"times_seen\": 8.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -1.103191327999132, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.0089, \"times_seen\": 41.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.015064323970578514, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.9381, \"times_seen\": 2.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.013942554462261378, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.35, \"times_seen\": 1.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.28336392351257134, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.085, \"times_seen\": 62.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.006758344474951583, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -1.4702, \"times_seen\": 22.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.627571062900943, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0149, \"times_seen\": 94.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.03657401185717742, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.1787, \"times_seen\": 50.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": -0.0008611823671452206, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.1835, \"times_seen\": 36.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": 0.02042985572066689, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0658, \"times_seen\": 25.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": 0.012504229458369417, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.0695, \"times_seen\": 17.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": -0.8254536604114581, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.1964, \"times_seen\": 29.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.08038342183160747, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.2658, \"times_seen\": 61.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.0007928930342667506, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -0.010742373972782769, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0698, \"times_seen\": 25.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": 0.009500253179027657, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0568, \"times_seen\": 47.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": -0.009378728526118119, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.1486, \"times_seen\": 23.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.2192993894827139, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0881, \"times_seen\": 144.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.11180620762253679, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0842, \"times_seen\": 74.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": -0.12949252800454178, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.066, \"times_seen\": 42.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.037939539767770585, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.1033, \"times_seen\": 91.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.1148878095853604, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.3422, \"times_seen\": 31.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"Y\", \"escape\": 0.7922594850109129, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.2037, \"times_seen\": 27.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": -0.002643723863985158, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -2.5362, \"times_seen\": 3.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.005729117035736826, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"A\", \"escape\": -0.09474373731815317, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0497, \"times_seen\": 61.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.08027927935015405, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.1599, \"times_seen\": 32.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.15167048540803957, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": -0.0215, \"times_seen\": 81.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.12112115915141893, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0698, \"times_seen\": 112.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.22589382798271687, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.1006, \"times_seen\": 106.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -1.929786483218272, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0377, \"times_seen\": 34.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.17317346514103515, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0392, \"times_seen\": 92.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": -0.01385445795213573, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.259406689997911, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.195, \"times_seen\": 80.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.019527830472290342, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.0663, \"times_seen\": 10.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.005260913914084385, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.12932764068679714, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.3117, \"times_seen\": 42.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.09012917554846836, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.2283, \"times_seen\": 35.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.005082998757075819, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.021241820235821923, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.1606, \"times_seen\": 23.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.003844769283515732, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.7865, \"times_seen\": 2.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.3575511804482495, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.0314, \"times_seen\": 85.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.07488305692605617, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": 0.1262, \"times_seen\": 29.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 1.3917037065063844, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.2179, \"times_seen\": 2.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.15768787060756204, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.0629, \"times_seen\": 59.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.7092194101512115, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0214, \"times_seen\": 21.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.011844221835215983, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -0.7442, \"times_seen\": 3.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.020013929315288982, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0388, \"times_seen\": 148.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": -0.0016942762371975986, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.1299, \"times_seen\": 1.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.06315076609515774, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -0.3251, \"times_seen\": 11.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.09190332547886598, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0186, \"times_seen\": 76.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.09248268748701112, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0614, \"times_seen\": 67.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.002438628712050942, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.008463235271847409, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.2852, \"times_seen\": 21.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.01778861123486189, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.0948, \"times_seen\": 8.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.03852009481102693, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.1903, \"times_seen\": 17.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.06994146841218092, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.392, \"times_seen\": 24.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.24976766837266937, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.0292, \"times_seen\": 27.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": -0.005735924842121192, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 0.041239760458466654, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": 0.186, \"times_seen\": 22.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.00818430875579613, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.059, \"times_seen\": 5.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.011945297470933758, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.6553, \"times_seen\": 21.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 1.2106925362890701, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.4981, \"times_seen\": 21.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.04094431712418512, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.3446, \"times_seen\": 35.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.012717730959210676, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.1164, \"times_seen\": 45.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.04506888002767069, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.0951, \"times_seen\": 20.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.0006367778240393574, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.4194, \"times_seen\": 1.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"-\", \"escape\": -0.0008350796580733831, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.013056319120539844, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0621, \"times_seen\": 4.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"L\", \"escape\": 0.00614911230770489, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0907, \"times_seen\": 10.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.5046820940239057, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.2213, \"times_seen\": 59.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.15963525248443608, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.2596, \"times_seen\": 37.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.3849769556382412, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0478, \"times_seen\": 62.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.026387995062143295, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.4219, \"times_seen\": 19.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.000950029165446493, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -1.5856, \"times_seen\": 1.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.025539675554259463, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -1.0889, \"times_seen\": 27.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.01799507795622616, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.2426, \"times_seen\": 12.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.9001272089061643, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.1875, \"times_seen\": 22.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.03117993330961832, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.3201, \"times_seen\": 15.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.031034997783313114, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.4335, \"times_seen\": 5.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.03918886224526755, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2905, \"times_seen\": 66.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.4414498370402645, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.7802, \"times_seen\": 38.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": -0.054207403181958935, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.9151, \"times_seen\": 28.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -0.019444037530087596, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -1.1258, \"times_seen\": 30.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.21533176738989443, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.4019, \"times_seen\": 42.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.051180875455021306, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.6579, \"times_seen\": 15.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"H\", \"escape\": -0.04086439601280327, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2005, \"times_seen\": 22.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.038034647856044934, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2854, \"times_seen\": 26.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"K\", \"escape\": -0.03698509864889162, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2019, \"times_seen\": 21.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.16562642941296513, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3821, \"times_seen\": 81.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.16584504238270925, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.03, \"times_seen\": 44.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"N\", \"escape\": -0.005035404024785171, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3721, \"times_seen\": 13.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"P\", \"escape\": -0.2192355803209622, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.5789, \"times_seen\": 39.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": -0.05719759012875535, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3196, \"times_seen\": 28.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": -1.1517190785639306, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2285, \"times_seen\": 104.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.05848827733699265, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.7665, \"times_seen\": 73.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": -0.01813010842521592, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.7113, \"times_seen\": 30.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"W\", \"escape\": -0.006112007369739311, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": 0.0842, \"times_seen\": 25.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.042599177764429154, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3186, \"times_seen\": 24.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"*\", \"escape\": -0.010294335999466664, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -2.882, \"times_seen\": 6.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.041281687588143844, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.1103, \"times_seen\": 22.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.0010259119826368296, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -0.046904202796755626, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": -0.1009, \"times_seen\": 20.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.8216075856506351, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.1073, \"times_seen\": 41.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 0.561630853997495, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.0916, \"times_seen\": 26.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.002605899158648632, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": -0.1074, \"times_seen\": 34.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.009281429738710807, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.0489, \"times_seen\": 29.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.0016295298731227982, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.1337, \"times_seen\": 2.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 0.02706165068844809, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.008, \"times_seen\": 31.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": -0.024597559821812293, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": -0.031, \"times_seen\": 8.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.03165799202257291, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.0274, \"times_seen\": 22.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.02043465276439303, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.191, \"times_seen\": 23.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.007640437312811962, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.1389, \"times_seen\": 35.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.0001223920801106046, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.3638, \"times_seen\": 21.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"H\", \"escape\": 0.007855858851476081, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.878, \"times_seen\": 8.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.014957215001062903, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.3533, \"times_seen\": 3.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.003358013062592833, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.3435, \"times_seen\": 1.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.000884053833502977, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.0605, \"times_seen\": 5.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.010207354289065097, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.2336, \"times_seen\": 34.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.022938015388661092, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.2389, \"times_seen\": 16.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.008254653182561841, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": -0.0602, \"times_seen\": 13.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.44051096558916686, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0837, \"times_seen\": 86.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.02377800982620286, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0438, \"times_seen\": 19.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"P\", \"escape\": 0.00798172605739672, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": -1.8418, \"times_seen\": 6.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.013163107918090439, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.1147, \"times_seen\": 35.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"S\", \"escape\": 0.015523686795698842, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0368, \"times_seen\": 11.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.036167806675614124, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.328, \"times_seen\": 35.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.05244160143789889, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.022, \"times_seen\": 16.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.37299648492917664, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.1419, \"times_seen\": 65.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.003652012530394631, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": 0.0397, \"times_seen\": 32.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.42887579968647865, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.0624, \"times_seen\": 63.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.013545307792202137, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.0284, \"times_seen\": 23.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.0027560107183038527, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.2404, \"times_seen\": 21.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.04789120540048185, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -0.1308, \"times_seen\": 14.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"I\", \"escape\": -0.007666768188270007, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -2.2387, \"times_seen\": 2.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.08844199336251335, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.0599, \"times_seen\": 64.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.02876962302621854, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.1102, \"times_seen\": 43.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.0021514776344204616, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -2.2533, \"times_seen\": 1.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.003137129187327965, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -1.1997, \"times_seen\": 1.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.010967956767381017, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.0006, \"times_seen\": 9.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.0491972727008458, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.1599, \"times_seen\": 19.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.004458751978713151, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -3.0473, \"times_seen\": 1.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.0044012280179098395, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -1.5486, \"times_seen\": 2.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.020629904591682107, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.3074, \"times_seen\": 31.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.0067967148355573105, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0134, \"times_seen\": 36.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": -0.25772086972958685, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.2674, \"times_seen\": 96.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": 0.0032116138452022184, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0345, \"times_seen\": 13.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"M\", \"escape\": 0.01547027406149126, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -0.0548, \"times_seen\": 17.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.07271050061356638, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0246, \"times_seen\": 105.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"T\", \"escape\": -0.020630257281232432, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.029, \"times_seen\": 13.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": -0.005069366245901854, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -1.9232, \"times_seen\": 1.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.18342426172237972, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.073, \"times_seen\": 95.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"C\", \"escape\": -0.02652724228466536, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.1659, \"times_seen\": 59.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.15187705651536587, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -0.3745, \"times_seen\": 14.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"I\", \"escape\": -0.010079409432547893, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.091, \"times_seen\": 2.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.015191562806414975, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.157, \"times_seen\": 9.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"L\", \"escape\": -0.03656029286717108, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.0256, \"times_seen\": 41.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"N\", \"escape\": -0.054024595269710735, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.0854, \"times_seen\": 20.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"S\", \"escape\": -0.05294179493197626, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -0.0833, \"times_seen\": 84.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"T\", \"escape\": -0.014605128250841851, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -0.1672, \"times_seen\": 1.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.028556247030774543, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": 0.4069, \"times_seen\": 15.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.009871638513268801, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -0.178, \"times_seen\": 15.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.010642018512605187, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -0.0126, \"times_seen\": 4.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.0005037673250021694, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -2.4142, \"times_seen\": 1.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.009051454631843188, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -2.1079, \"times_seen\": 1.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.003080562684977678, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -2.0339, \"times_seen\": 1.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.4248948378177442, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": 0.3598, \"times_seen\": 44.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.011131213618430677, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": 0.0092, \"times_seen\": 5.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": 0.014236742541736359, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.3623, \"times_seen\": 23.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.0016744003263923562, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.2011, \"times_seen\": 36.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.05841875837814173, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.1086, \"times_seen\": 28.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.0054996376528601626, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.02, \"times_seen\": 22.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.038694888703074845, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.1487, \"times_seen\": 36.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.03452211974471077, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -0.0764, \"times_seen\": 45.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.3668797097593463, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.1741, \"times_seen\": 70.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.06063275069755027, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.0898, \"times_seen\": 45.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.04013668544213805, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.0326, \"times_seen\": 130.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": -0.0972480460364084, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -0.1775, \"times_seen\": 21.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"R\", \"escape\": -0.03706906579044136, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -0.3296, \"times_seen\": 17.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": 0.00027459673900097754, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.2637, \"times_seen\": 12.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.0025635101109068676, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.1173, \"times_seen\": 33.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.5944047965869294, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -2.5368, \"times_seen\": 2.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.034842347398897355, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.2116, \"times_seen\": 18.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": -0.11316097859611933, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.1328, \"times_seen\": 35.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": -0.012228990634355489, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": -1.4251894330128263, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -0.1789, \"times_seen\": 38.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.012242724299157253, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -0.061, \"times_seen\": 1.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.0216392711673271, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -0.0626, \"times_seen\": 16.0}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": -0.009847013288383099, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.0999, \"times_seen\": 3.0}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.051250490678890655, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": 0.2268, \"times_seen\": 49.0}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.03932936234192997, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.0464, \"times_seen\": 57.0}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.03686387370829708, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.6084, \"times_seen\": 42.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": -0.042721933124979294, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0125, \"times_seen\": 72.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": -0.012609840470580275, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0765, \"times_seen\": 35.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": -1.7360467020302282, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.254, \"times_seen\": 38.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.005764624010269194, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.1586, \"times_seen\": 53.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": 1.2487635028492108, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0813, \"times_seen\": 44.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.10925685200476862, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.3656, \"times_seen\": 101.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": -0.03321171740747852, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0095, \"times_seen\": 23.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 0.0003327225878243435, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0895, \"times_seen\": 30.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": 0.29057738498401203, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0082, \"times_seen\": 94.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.0051762929821269526, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0308, \"times_seen\": 57.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.0589730579385037, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0363, \"times_seen\": 102.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 0.04988972490766611, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -2.8372, \"times_seen\": 6.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.10000606526168722, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0239, \"times_seen\": 43.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.02672037017464495, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.077, \"times_seen\": 153.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": -0.29049259788270365, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0966, \"times_seen\": 80.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.06530834785119796, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.1724, \"times_seen\": 74.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": -0.43301912058720615, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0846, \"times_seen\": 94.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": -0.06374502683653833, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0432, \"times_seen\": 39.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": 0.7893116598750429, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0513, \"times_seen\": 22.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": 0.012804440220581663, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -2.9248, \"times_seen\": 4.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.17359192505340743, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.0737, \"times_seen\": 84.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.9022666879583082, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.1333, \"times_seen\": 26.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.05295115238116348, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.2161, \"times_seen\": 28.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.5991663227934282, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.2615, \"times_seen\": 42.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 0.3855585308263001, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.1757, \"times_seen\": 71.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.24295056780682356, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.0432, \"times_seen\": 71.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": -0.05306022544823269, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.1824, \"times_seen\": 31.0}, {\"site\": 1190, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.008156670003826309, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": 0.1436, \"times_seen\": 11.0}, {\"site\": 1190, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.0010019147126594902, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -3.0572, \"times_seen\": 7.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.0032121977340038256, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.2563, \"times_seen\": 2.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.017920157503639778, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.0998, \"times_seen\": 11.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -0.044513747295185625, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.1808, \"times_seen\": 25.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.015554002064991064, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -0.4681, \"times_seen\": 14.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": -0.002771097722138549, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -0.7439, \"times_seen\": 1.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.011255695741672737, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.0239, \"times_seen\": 10.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.017973194977780275, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.1746, \"times_seen\": 8.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.13269040188745562, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.0335, \"times_seen\": 49.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.30337647886444047, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": 0.0492, \"times_seen\": 62.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.04732120513090366, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.2683, \"times_seen\": 79.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.05611445346847117, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.1986, \"times_seen\": 25.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": -0.02811154126848277, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.1909, \"times_seen\": 9.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.00449049940465827, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": 0.0115, \"times_seen\": 14.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.005669638194204843, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -2.6467, \"times_seen\": 2.0}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -2.680899075259671, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -1.122, \"times_seen\": 36.0}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -2.0086742888936033, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -0.0384, \"times_seen\": 29.0}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.2711566709967855, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -1.4316, \"times_seen\": 26.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.13504009757344948, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.2202, \"times_seen\": 30.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.006154062914168038, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.066, \"times_seen\": 12.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.09196809274470405, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": 0.0823, \"times_seen\": 35.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.16791058627484745, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -2.5545, \"times_seen\": 25.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0069264026973222675, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -1.8685, \"times_seen\": 2.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.02252006959159764, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.832, \"times_seen\": 8.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": 0.018963448214299555, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.0012683283442100042, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.4286, \"times_seen\": 4.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.035607176435583775, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.5658, \"times_seen\": 8.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.03054800398458769, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.3756, \"times_seen\": 17.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.015094687292884705, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": 0.0335, \"times_seen\": 32.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"-\", \"escape\": 0.018277047701202927, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": -0.025784718697845165, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.3481, \"times_seen\": 24.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"G\", \"escape\": 0.0668492320008881, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.5742, \"times_seen\": 98.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"H\", \"escape\": -0.04180307923277616, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.7052, \"times_seen\": 45.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.006725258951477987, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.3864, \"times_seen\": 124.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"S\", \"escape\": -0.4021349610704598, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.4627, \"times_seen\": 21.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.06627415532883206, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.6228, \"times_seen\": 14.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"Y\", \"escape\": -0.006895839158365799, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.6752, \"times_seen\": 80.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"-\", \"escape\": 0.01803818670299711, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.6123368294975281, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.6132, \"times_seen\": 115.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": 0.0005683465785518532, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -1.243, \"times_seen\": 2.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.04439476830253635, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.2187, \"times_seen\": 119.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.03909887145214431, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -1.2615, \"times_seen\": 17.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.005100924717762745, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.891, \"times_seen\": 2.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.024437951522037912, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.4283, \"times_seen\": 17.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": 0.04011920171324463, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": 0.1791, \"times_seen\": 14.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": 0.12968462245451276, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.1289, \"times_seen\": 77.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": 0.07575477388580935, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.0713, \"times_seen\": 48.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.05795670447128559, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.2985, \"times_seen\": 86.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"N\", \"escape\": -0.028038875535480307, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.1313, \"times_seen\": 14.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.10779419818649819, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.0902, \"times_seen\": 72.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": 0.028112820785090874, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.2665, \"times_seen\": 11.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.12520215721739433, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.1355, \"times_seen\": 30.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": -0.04661730436384486, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.5713, \"times_seen\": 54.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": 0.4042367027950606, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.5992, \"times_seen\": 119.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"Q\", \"escape\": 0.3449844710284428, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.2673, \"times_seen\": 22.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"S\", \"escape\": -0.055179049284814, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.4779, \"times_seen\": 7.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": 0.03971320492974471, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.4334, \"times_seen\": 13.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -5.29854352829695e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -3.0098, \"times_seen\": 1.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.12026478972380765, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -0.5025, \"times_seen\": 48.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.018371027364283806, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -2.377, \"times_seen\": 5.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": 0.014085892980543913, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -0.37, \"times_seen\": 12.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.055543132832342315, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -0.075, \"times_seen\": 28.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.005767152344332407, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.7428, \"times_seen\": 12.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.16924354363623245, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.8301, \"times_seen\": 8.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.0030105352982229073, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.7863, \"times_seen\": 2.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.0031704722954887872, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.007, \"times_seen\": 1.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.011647359575944087, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.4525, \"times_seen\": 2.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.013341925746566664, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -1.2555, \"times_seen\": 4.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.07246828568541053, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.3785, \"times_seen\": 34.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.01302168398836315, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.9138, \"times_seen\": 2.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.021486446883696792, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.8861, \"times_seen\": 8.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.055712985556084255, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.3427, \"times_seen\": 31.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -1.4715051810630286, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -1.2251, \"times_seen\": 12.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 0.09466689284419941, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.1113, \"times_seen\": 12.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.006367106500601575, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.004966208059278022, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.1242, \"times_seen\": 56.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.0011285368286116438, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": -0.0272, \"times_seen\": 17.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.04820449563684073, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 0.1383322386589836, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.1046, \"times_seen\": 22.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": 0.005714386430603556, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -1.5381, \"times_seen\": 7.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.026994022238870763, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -0.1585, \"times_seen\": 21.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.005736488629857277, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -0.9419, \"times_seen\": 13.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.0067722990102297995, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -1.0559, \"times_seen\": 2.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": -0.0016657929393783548, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -0.5054, \"times_seen\": 1.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"-\", \"escape\": -0.0017897625050210288, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"A\", \"escape\": -0.005313448966342953, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.9284, \"times_seen\": 8.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"D\", \"escape\": -0.3352444868413625, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.2349, \"times_seen\": 79.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"G\", \"escape\": 0.0018747799838966267, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.075, \"times_seen\": 14.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"K\", \"escape\": -0.01531649203473622, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.1686, \"times_seen\": 91.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"V\", \"escape\": -0.01276069020608521, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.544, \"times_seen\": 20.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"*\", \"escape\": -0.0038178165919106736, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.7288, \"times_seen\": 1.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"-\", \"escape\": -0.0030917281585902566, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"E\", \"escape\": -0.012403766099800614, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": 0.2082, \"times_seen\": 101.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"H\", \"escape\": -0.19113046897869246, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -0.5391, \"times_seen\": 131.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"K\", \"escape\": -0.03540489191707268, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -1.0514, \"times_seen\": 61.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"L\", \"escape\": -0.05023365356210644, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -0.3741, \"times_seen\": 25.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"R\", \"escape\": -0.18649968793638147, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -1.2458, \"times_seen\": 30.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"-\", \"escape\": -0.004076289010200386, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.01025464807668718, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.5884, \"times_seen\": 5.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.005345629529097193, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -0.9888, \"times_seen\": 1.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.08407447083051521, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.1283, \"times_seen\": 22.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"I\", \"escape\": -0.0015182459977329847, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -0.3489, \"times_seen\": 1.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.004285801816824064, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.2513, \"times_seen\": 1.0}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.007892657667270335, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.2619, \"times_seen\": 14.0}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.8410239910532221, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.1508, \"times_seen\": 17.0}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.030817768779081087, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.6196, \"times_seen\": 43.0}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.45249250269698343, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.0089, \"times_seen\": 38.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.019359075826306395, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -2.2165, \"times_seen\": 6.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.0015654355919223154, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.5475, \"times_seen\": 2.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 0.06648499151910059, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.6971, \"times_seen\": 21.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.007602923785953903, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.1191, \"times_seen\": 5.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.033036826145036315, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.3843, \"times_seen\": 14.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"G\", \"escape\": -0.0019249337899821283, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.2355, \"times_seen\": 1.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": 0.015409072223604645, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.2128, \"times_seen\": 14.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.004621768249593197, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.4587, \"times_seen\": 2.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": 0.030107871337851512, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.4534, \"times_seen\": 5.0}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"L\", \"escape\": -0.006603976725546984, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -2.2115, \"times_seen\": 3.0}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"Q\", \"escape\": -0.03548528385944045, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.333, \"times_seen\": 6.0}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"S\", \"escape\": -0.06852953662219403, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.0767, \"times_seen\": 37.0}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"T\", \"escape\": -0.005058323153869729, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.9568, \"times_seen\": 4.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.024860921407809718, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -2.5278, \"times_seen\": 19.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"F\", \"escape\": 0.018992049498867247, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -0.6012, \"times_seen\": 19.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"G\", \"escape\": 0.034460695271636886, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -1.6721, \"times_seen\": 11.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": 0.05636461267937563, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -1.6378, \"times_seen\": 23.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": -0.015082381254701882, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"S\", \"escape\": -0.00434545584237613, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -1.5455, \"times_seen\": 1.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": -0.014538065065294353, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -2.4638, \"times_seen\": 8.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.023595148228587073, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -2.2095, \"times_seen\": 6.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.05937121193423362, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -0.3552, \"times_seen\": 50.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 0.17949776343985896, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -1.0761, \"times_seen\": 111.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": -0.25157051337232206, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -0.9324, \"times_seen\": 37.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.4518854015840662, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -1.6606, \"times_seen\": 39.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.008872357902907179, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.6364, \"times_seen\": 35.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.07770184396512192, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.7324, \"times_seen\": 45.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.0018809439650867377, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.375, \"times_seen\": 1.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.5317557254939903, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.4035, \"times_seen\": 72.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.535412627936337, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.1313, \"times_seen\": 114.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.03543068435912523, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.0003, \"times_seen\": 69.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"C\", \"escape\": -0.012389454019051515, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -1.7056, \"times_seen\": 3.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"L\", \"escape\": -0.0038347008145019888, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -1.4455, \"times_seen\": 59.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"R\", \"escape\": 0.01805035810679752, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -2.4405, \"times_seen\": 1.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"*\", \"escape\": 0.004563402089866463, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -2.8152, \"times_seen\": 8.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0827319085903491, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.4166, \"times_seen\": 12.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.02717860529447296, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.5232, \"times_seen\": 6.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.012979014590863227, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -1.3295, \"times_seen\": 12.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.0036108953295143384, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -1.5515, \"times_seen\": 1.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.003682683426148261, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.9749, \"times_seen\": 1.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.45631602359221296, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.3553, \"times_seen\": 153.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.3871551689770387, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.3015, \"times_seen\": 136.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 0.04655249728686854, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.747, \"times_seen\": 89.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.24017165322065426, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.219, \"times_seen\": 52.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"F\", \"escape\": 0.006800014762828369, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.0226, \"times_seen\": 32.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"H\", \"escape\": -0.08851736978358062, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.5841, \"times_seen\": 20.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"I\", \"escape\": 0.03275314950849078, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.1738, \"times_seen\": 43.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"K\", \"escape\": 0.13169592850543554, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -1.1434, \"times_seen\": 27.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -4.069444794244274, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.0576, \"times_seen\": 87.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"M\", \"escape\": 0.02631461240384466, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.1474, \"times_seen\": 22.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"N\", \"escape\": -0.01612866356936502, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.1172, \"times_seen\": 28.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"P\", \"escape\": -0.07150724830665796, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.8864, \"times_seen\": 48.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"Q\", \"escape\": -0.11063902966462763, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.063, \"times_seen\": 24.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.017546477685277114, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -1.5016, \"times_seen\": 105.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.6582100955256218, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.0718, \"times_seen\": 263.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"T\", \"escape\": 0.15022621020141563, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.0003, \"times_seen\": 56.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.01561800222309166, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.0735, \"times_seen\": 166.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": -0.03218283502832053, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.1293, \"times_seen\": 51.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"Y\", \"escape\": 0.7426689674561558, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.5349, \"times_seen\": 27.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"*\", \"escape\": 0.008184575822868006, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -2.5133, \"times_seen\": 9.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"I\", \"escape\": 0.08097851183751167, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.1032, \"times_seen\": 79.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"L\", \"escape\": -0.012772229140204252, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.0528, \"times_seen\": 26.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"S\", \"escape\": -0.046264007142032916, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -2.1484, \"times_seen\": 11.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"V\", \"escape\": 0.010221585172063312, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.2837, \"times_seen\": 4.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"Y\", \"escape\": -0.005131947602967781, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -0.9808, \"times_seen\": 2.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.03908604732739996, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": 0.065, \"times_seen\": 36.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.008813628788230301, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.1515, \"times_seen\": 48.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.01743610669108732, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.4276, \"times_seen\": 6.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.6247247608005602, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.0778, \"times_seen\": 52.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.6616006718974253, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.1469, \"times_seen\": 133.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"Y\", \"escape\": -0.017597796217119134, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -1.1376, \"times_seen\": 23.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"D\", \"escape\": 0.007033848651956657, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.2087, \"times_seen\": 5.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"P\", \"escape\": 0.006348377990972035, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.1067, \"times_seen\": 1.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": 0.01621068447813895, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.0033, \"times_seen\": 39.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": 0.2475291278427342, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": -0.0723, \"times_seen\": 95.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.44478328611944024, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": -0.6226, \"times_seen\": 79.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.01421509509087006, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.387, \"times_seen\": 1.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.001232483884725643, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.4959, \"times_seen\": 29.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": -0.011231276378394207, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -1.5139, \"times_seen\": 11.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": -0.08954661941601155, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -2.5374, \"times_seen\": 22.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.00037194671154744066, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.6865, \"times_seen\": 41.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.03628141204582952, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.8444, \"times_seen\": 19.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"W\", \"escape\": 0.03349647583062863, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -1.0369, \"times_seen\": 19.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": -0.06673751436374394, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.2175, \"times_seen\": 34.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.009265541001294682, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.04856208700395803, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.0817, \"times_seen\": 24.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.007261292135070781, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -1.9729, \"times_seen\": 1.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": -0.028950042201685525, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.298, \"times_seen\": 44.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.023384090057231088, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.2853, \"times_seen\": 16.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": 0.014164265095107716, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.1961, \"times_seen\": 50.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.06946784342883124, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.0194, \"times_seen\": 17.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.3617183243083687, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.2032, \"times_seen\": 21.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": 0.012741547200316838, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.173, \"times_seen\": 3.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": -0.012369929023412704, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.2097, \"times_seen\": 19.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.05326305371215872, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.1205, \"times_seen\": 16.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.006047845603823413, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.1733, \"times_seen\": 40.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"E\", \"escape\": 0.0006146651491050261, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -1.1596, \"times_seen\": 5.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"S\", \"escape\": -0.0011393902726009846, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.3103, \"times_seen\": 21.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"T\", \"escape\": -0.5173313329222792, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.0057, \"times_seen\": 66.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"V\", \"escape\": 0.15671682354072694, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.1725, \"times_seen\": 94.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.0019623143033263134, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -2.3523, \"times_seen\": 1.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": -0.0175843513158756, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -2.8078, \"times_seen\": 7.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": 0.0010785141782119444, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.6899, \"times_seen\": 13.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": 0.4675363368332893, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.1915, \"times_seen\": 77.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"N\", \"escape\": -0.01671575025549109, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -1.8437, \"times_seen\": 3.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": -0.03139668491580162, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.466, \"times_seen\": 13.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": 0.07018563294733224, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.2212, \"times_seen\": 41.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.01018844165829586, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0799, \"times_seen\": 139.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"C\", \"escape\": -0.21929628997753814, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.0272, \"times_seen\": 55.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"D\", \"escape\": 1.1127202301070414, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -1.5675, \"times_seen\": 37.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": -1.4402634300935693, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -1.0143, \"times_seen\": 89.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 0.22182400703516195, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.1416, \"times_seen\": 65.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.014789026123897165, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.1317, \"times_seen\": 139.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"H\", \"escape\": 0.01046191292549271, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.8873, \"times_seen\": 39.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.1753637013397059, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0404, \"times_seen\": 95.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"K\", \"escape\": -0.04928065045132254, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.7357, \"times_seen\": 42.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.05312210610603046, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0479, \"times_seen\": 209.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.17759089428173686, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0496, \"times_seen\": 59.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"N\", \"escape\": -0.041372009125573456, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.8236, \"times_seen\": 33.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"P\", \"escape\": -1.2367395143645754, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.7, \"times_seen\": 66.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"Q\", \"escape\": -0.5295115901698232, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.7127, \"times_seen\": 46.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"R\", \"escape\": -0.01428970475843655, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -2.7184, \"times_seen\": 47.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"S\", \"escape\": 0.04327924666128949, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.1117, \"times_seen\": 95.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"T\", \"escape\": 0.1809862186292571, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.1155, \"times_seen\": 92.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"W\", \"escape\": 0.03237792483457191, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.3215, \"times_seen\": 55.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"Y\", \"escape\": -0.04595030646692132, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.723, \"times_seen\": 45.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"*\", \"escape\": 0.01921411617564154, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -2.4181, \"times_seen\": 10.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": 0.02443281176374709, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -1.0511, \"times_seen\": 1.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": 0.023749156521935776, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.2766, \"times_seen\": 98.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"K\", \"escape\": -0.009315868720531013, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": 0.2572, \"times_seen\": 2.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.8207678406856297, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.1168, \"times_seen\": 41.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"R\", \"escape\": -0.007011958560214287, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -1.5001, \"times_seen\": 1.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.10238412632773293, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": 0.0645, \"times_seen\": 57.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": 0.011509048121806972, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.2728, \"times_seen\": 81.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"-\", \"escape\": 0.021073414026824132, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": -0.017339959860509162, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0708, \"times_seen\": 16.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 0.02456433228366677, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0254, \"times_seen\": 14.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": -0.027622875100035506, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0927, \"times_seen\": 43.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": -0.1463566113285704, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0999, \"times_seen\": 48.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"-\", \"escape\": -0.012217707418836403, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": 0.03849895861077194, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": 0.1554, \"times_seen\": 49.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.63745550159183, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": -0.5252, \"times_seen\": 53.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"K\", \"escape\": 0.005733410651398976, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": -1.7746, \"times_seen\": 17.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.013207763372173852, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": 0.3093, \"times_seen\": 8.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.01577800694624413, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"F\", \"escape\": -0.007459196173045506, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.1186, \"times_seen\": 8.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"K\", \"escape\": -0.01090305583671359, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": 0.0471, \"times_seen\": 4.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"L\", \"escape\": -0.0066638698596192935, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.1578, \"times_seen\": 15.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"M\", \"escape\": -0.006835226012560026, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.1257, \"times_seen\": 2.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"S\", \"escape\": 0.012105855941235135, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.4748, \"times_seen\": 14.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"T\", \"escape\": 0.02128986722394584, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.2131, \"times_seen\": 31.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"V\", \"escape\": -0.025038091480516608, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": 0.0215, \"times_seen\": 40.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": 0.039409938956075384, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.0475, \"times_seen\": 125.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"K\", \"escape\": -0.006890577758335106, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -1.3499, \"times_seen\": 1.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.08366171116791693, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.0947, \"times_seen\": 26.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"Q\", \"escape\": 0.02739872432070221, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.8916, \"times_seen\": 5.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": -0.004896770368945582, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.1748, \"times_seen\": 52.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": -0.05755965662573356, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": 0.0275, \"times_seen\": 99.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"-\", \"escape\": -0.004217253880509596, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": 0.3177, \"times_seen\": 1.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 4.8948493369423515e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.1091, \"times_seen\": 32.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0017805006619633307, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.0854, \"times_seen\": 11.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 6.792499290275926e-06, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.1194, \"times_seen\": 9.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.06312234112809968, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.6804, \"times_seen\": 25.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.007691100679017429, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.7067, \"times_seen\": 3.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.012147722062538021, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -2.3997, \"times_seen\": 1.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.004145481511174274, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.009613947250836497, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.1193, \"times_seen\": 71.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.07432579260979583, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.0483, \"times_seen\": 17.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.0039864928968311175, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -1.224, \"times_seen\": 1.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.020213414689907894, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.4282, \"times_seen\": 29.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.035216334314401944, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -1.4152, \"times_seen\": 8.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": -0.004704017300387356, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -2.6874, \"times_seen\": 2.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": -0.00807271979721577, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -2.8968, \"times_seen\": 4.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.35873421517765997, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -0.4074, \"times_seen\": 50.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.006984677244766716, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -1.1882, \"times_seen\": 3.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.40250257985418986, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -0.4697, \"times_seen\": 55.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.004364476032117216, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -1.3228, \"times_seen\": 57.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": -0.006954158516958492, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"I\", \"escape\": -0.021795279408208048, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": 0.0143, \"times_seen\": 86.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"K\", \"escape\": 0.006482993302097249, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -1.6031, \"times_seen\": 30.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"L\", \"escape\": -0.07666490790778029, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -0.0706, \"times_seen\": 29.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"R\", \"escape\": -0.002160224893933378, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -1.1254, \"times_seen\": 1.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"T\", \"escape\": 0.37196238361837286, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -0.4804, \"times_seen\": 61.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"V\", \"escape\": -0.14411468659615528, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -0.032, \"times_seen\": 81.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"-\", \"escape\": -0.0023596542104404213, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"A\", \"escape\": -0.04007066033944411, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -0.0204, \"times_seen\": 38.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"I\", \"escape\": -0.17304331560363126, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -0.004, \"times_seen\": 106.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"N\", \"escape\": -2.734234928175823, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -1.0371, \"times_seen\": 69.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"S\", \"escape\": -0.031360966666898166, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": 0.0467, \"times_seen\": 38.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"-\", \"escape\": -0.027279397675186775, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.03914468317627465, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.1208, \"times_seen\": 55.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.009647696126645004, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -1.3003, \"times_seen\": 4.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.07413926718822039, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.2297, \"times_seen\": 60.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.9832326425846635, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.5828, \"times_seen\": 49.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.006364805731285753, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.3604, \"times_seen\": 31.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 1.6576895538979888, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -1.0785, \"times_seen\": 21.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.7237826476216476, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": 0.0624, \"times_seen\": 114.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -0.026727799153386734, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.2845, \"times_seen\": 3.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.007311591787222636, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.8685, \"times_seen\": 5.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.0878126228980527, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.1106, \"times_seen\": 25.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": 0.06761043966271969, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.5082, \"times_seen\": 16.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.0024844957951508776, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -1.4729, \"times_seen\": 32.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.013500526481148883, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -1.1017, \"times_seen\": 14.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": 0.04415595685018777, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.9946, \"times_seen\": 28.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": -0.0020615974752105615, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -2.0316, \"times_seen\": 3.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": -0.005362868374523065, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.6744, \"times_seen\": 9.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 1.3407009465767155, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.2409, \"times_seen\": 22.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": -0.0031801608727977933, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -2.1346, \"times_seen\": 1.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.01059946906667198, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -1.4508, \"times_seen\": 10.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.008240495290712541, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.5981, \"times_seen\": 14.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": -0.002511603245470232, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.7344, \"times_seen\": 1.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -1.038465202181355, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.7287, \"times_seen\": 76.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": -0.02283502951447606, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -1.7553, \"times_seen\": 4.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": -0.007103967878270874, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": 0.1308, \"times_seen\": 9.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.0003673503764308883, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.1894, \"times_seen\": 1.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": -0.006826299021186597, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.2464, \"times_seen\": 10.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.3045961267928623, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.1266, \"times_seen\": 30.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.029724596909832677, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.0166, \"times_seen\": 66.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 0.004457832694277048, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.1954, \"times_seen\": 1.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.6484915919381884, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.3422, \"times_seen\": 64.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.010660739115040698, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.1987, \"times_seen\": 64.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.1041798599156507, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": -0.0017854593608446268, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.0966, \"times_seen\": 8.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.08004384265695594, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.1029, \"times_seen\": 41.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": -0.0005189246591944089, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.3107, \"times_seen\": 1.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.3092665006530307, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.8646, \"times_seen\": 24.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": -0.019993172123690332, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.1091, \"times_seen\": 7.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": 0.14120435718571556, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.324, \"times_seen\": 15.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": 0.12764505772567375, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.3527, \"times_seen\": 53.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.020849523242356022, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.5323, \"times_seen\": 48.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": 0.013678575971271464, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -1.052, \"times_seen\": 1.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": -0.0044261804156018, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.004504870337717969, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.1396, \"times_seen\": 30.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.015374272052857841, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.0979, \"times_seen\": 11.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.019226907040552965, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.1033, \"times_seen\": 9.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.30481271309743113, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.8224, \"times_seen\": 56.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.011013587808311107, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.5007, \"times_seen\": 3.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.004429698567700783, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.2253, \"times_seen\": 1.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.027514441324949325, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": -0.005699310766762545, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.008844077114536516, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.2488, \"times_seen\": 37.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.009445901048281979, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": -0.8984508268116926, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": 0.0314, \"times_seen\": 28.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.6029510239653002, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.0857, \"times_seen\": 57.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.02593283769974384, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.6612, \"times_seen\": 4.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 0.026189379963023188, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.0745, \"times_seen\": 79.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.055765702737242615, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.2072, \"times_seen\": 14.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"-\", \"escape\": -0.009190278944759715, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": 0.001148676636937065, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": 0.1369, \"times_seen\": 1.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": 0.07059091256675346, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.1513, \"times_seen\": 72.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.10769058661975231, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.2387, \"times_seen\": 105.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 0.2471499531009845, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.0637, \"times_seen\": 71.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 0.027983417896736258, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.2773, \"times_seen\": 68.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": -0.002474047168978515, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": 0.1697, \"times_seen\": 6.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": -0.034262624911517825, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.3644, \"times_seen\": 62.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": 0.011229914501910918, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.8924, \"times_seen\": 2.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.04631072743333908, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.138, \"times_seen\": 24.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.029025674046347746, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.551, \"times_seen\": 31.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": 0.8368161910906591, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.3998, \"times_seen\": 43.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": 0.3123378879884355, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.3368, \"times_seen\": 26.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.0047518064903999966, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.815, \"times_seen\": 37.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": -0.0008078131456171574, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.5813, \"times_seen\": 1.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": -3.055206360510004e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -1.9998, \"times_seen\": 1.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.14200975645221856, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.1572, \"times_seen\": 69.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": -0.018645896953330084, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.5566, \"times_seen\": 16.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.010195521058329252, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.0698, \"times_seen\": 28.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": -0.25584510567588725, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.342, \"times_seen\": 32.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": 0.0005596707142661139, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.321, \"times_seen\": 16.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"V\", \"escape\": -0.09393327744982308, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.3538, \"times_seen\": 29.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": -0.03767540831500338, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.1295, \"times_seen\": 44.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.040559142807492274, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.4627, \"times_seen\": 85.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": -0.004110074221068422, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.4376, \"times_seen\": 1.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": 0.008523860406420407, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": 0.2266, \"times_seen\": 1.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.034737079842798814, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.005, \"times_seen\": 26.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.03581902405657926, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.0657, \"times_seen\": 36.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.028703540153350842, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.1038, \"times_seen\": 92.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 0.46254122832152633, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.219, \"times_seen\": 45.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.01819874965772799, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": 0.2124, \"times_seen\": 30.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 0.002824284102676309, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": 0.096, \"times_seen\": 30.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 0.014145042296436997, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.7342, \"times_seen\": 2.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"F\", \"escape\": 0.4801713002360181, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.0678, \"times_seen\": 122.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"G\", \"escape\": -0.9359007287423298, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.4042, \"times_seen\": 11.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"L\", \"escape\": -0.49747665936252805, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.086, \"times_seen\": 26.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"R\", \"escape\": 0.06107502264726517, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.0299, \"times_seen\": 99.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"S\", \"escape\": 0.012355726966342049, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.3167, \"times_seen\": 41.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"W\", \"escape\": -0.09883064620919153, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.0876, \"times_seen\": 45.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"Y\", \"escape\": -0.9936250950490966, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.0012, \"times_seen\": 125.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"*\", \"escape\": -0.006981695138645617, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"-\", \"escape\": 0.007722373354298279, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.3928, \"times_seen\": 2.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"A\", \"escape\": -0.014614265689905674, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0212, \"times_seen\": 9.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"C\", \"escape\": -0.0065547731887814235, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.4135, \"times_seen\": 3.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": -0.01938741799595861, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.1186, \"times_seen\": 40.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"E\", \"escape\": 0.20826193044070007, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0622, \"times_seen\": 55.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"L\", \"escape\": -0.002047313183033864, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.1906, \"times_seen\": 1.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 0.040132035896629246, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.2094, \"times_seen\": 63.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": -0.011800543595330164, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.3219, \"times_seen\": 18.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": -0.010907465928036689, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0905, \"times_seen\": 67.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"-\", \"escape\": 0.013014033424135967, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": -0.2543, \"times_seen\": 2.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.005965714755331725, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.0001, \"times_seen\": 81.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": -0.5441176820917278, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3963, \"times_seen\": 143.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": 0.03079798885178348, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.1111, \"times_seen\": 45.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": -0.046813985270082355, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.0168, \"times_seen\": 30.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.0028832447370043548, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.397, \"times_seen\": 141.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 0.17458364356068645, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.4074, \"times_seen\": 94.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 0.1394789845337935, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2924, \"times_seen\": 41.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": -0.064600654351964, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.4224, \"times_seen\": 50.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": -1.1049179963704814, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.1965, \"times_seen\": 40.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": -0.15596796231335436, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3611, \"times_seen\": 101.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": -0.014231982742209309, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2764, \"times_seen\": 31.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 0.01449473996032903, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.397, \"times_seen\": 36.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": -0.0014591785398810314, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2155, \"times_seen\": 158.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": 0.017093820169583468, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3237, \"times_seen\": 25.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.050851019227262206, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2863, \"times_seen\": 95.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": -0.014674057637537602, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.2164, \"times_seen\": 136.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": -0.14714166674323087, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3255, \"times_seen\": 99.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": -0.0029563900456530947, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2297, \"times_seen\": 29.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": -1.959268611976506, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.4444, \"times_seen\": 126.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": -0.019898714773713952, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.0346, \"times_seen\": 49.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 0.00757295007506384, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"L\", \"escape\": -0.010761985205118951, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.3678, \"times_seen\": 5.0}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"R\", \"escape\": -0.003524787161633356, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.397, \"times_seen\": 62.0}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"W\", \"escape\": -0.011371216663691657, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.397, \"times_seen\": 2.0}, {\"site\": 1, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 43, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 55, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 220, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 292, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 294, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 297, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 310, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 335, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 362, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 384, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 395, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 396, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 398, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 407, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 415, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 419, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 420, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 423, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 428, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 429, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 430, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 433, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 477, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 503, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 509, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 512, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 521, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 522, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 528, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 535, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 556, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 575, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 576, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 578, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 609, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 614, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 646, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 647, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 649, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 715, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 722, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 725, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 735, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 740, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 757, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 799, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 813, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 815, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 874, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 895, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 913, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 914, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 916, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 920, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 963, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 970, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 993, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 994, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"*\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": -2.3068, \"times_seen\": null}, {\"site\": 2, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": -0.206, \"times_seen\": null}, {\"site\": 6, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 6, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -3.1225, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -3.1479, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.7825, \"times_seen\": null}, {\"site\": 8, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 8, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -2.7606, \"times_seen\": null}, {\"site\": 9, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 10, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 11, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": -1.9748, \"times_seen\": null}, {\"site\": 12, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -3.2561, \"times_seen\": null}, {\"site\": 12, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 13, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 13, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.2003, \"times_seen\": null}, {\"site\": 13, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.4072, \"times_seen\": null}, {\"site\": 14, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": -2.7736, \"times_seen\": null}, {\"site\": 15, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": -3.2502, \"times_seen\": null}, {\"site\": 15, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.6185, \"times_seen\": null}, {\"site\": 16, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0858, \"times_seen\": null}, {\"site\": 16, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 17, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.8797, \"times_seen\": null}, {\"site\": 22, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.0432, \"times_seen\": null}, {\"site\": 23, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -1.1418, \"times_seen\": null}, {\"site\": 26, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 27, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 28, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -2.7365, \"times_seen\": null}, {\"site\": 28, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 28, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 31, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": 0.1285, \"times_seen\": null}, {\"site\": 31, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -3.1061, \"times_seen\": null}, {\"site\": 31, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 32, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 32, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -2.098, \"times_seen\": null}, {\"site\": 33, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 34, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 34, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.7648, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -1.9509, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 36, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 36, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -1.2668, \"times_seen\": null}, {\"site\": 37, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 37, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.2193, \"times_seen\": null}, {\"site\": 37, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -3.1105, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -2.77, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -1.4117, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 39, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 40, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 40, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.4397, \"times_seen\": null}, {\"site\": 41, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 41, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 42, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 42, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -3.3265, \"times_seen\": null}, {\"site\": 43, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": -3.1126, \"times_seen\": null}, {\"site\": 43, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": -2.939, \"times_seen\": null}, {\"site\": 43, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": -2.9977, \"times_seen\": null}, {\"site\": 44, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": 0.0669, \"times_seen\": null}, {\"site\": 45, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": 0.1193, \"times_seen\": null}, {\"site\": 46, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -0.3882, \"times_seen\": null}, {\"site\": 47, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -3.0776, \"times_seen\": null}, {\"site\": 47, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -1.3525, \"times_seen\": null}, {\"site\": 48, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -2.8194, \"times_seen\": null}, {\"site\": 49, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -1.9489, \"times_seen\": null}, {\"site\": 49, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -1.1338, \"times_seen\": null}, {\"site\": 49, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.3197, \"times_seen\": null}, {\"site\": 51, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": -3.205, \"times_seen\": null}, {\"site\": 52, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": -2.8375, \"times_seen\": null}, {\"site\": 53, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": -2.9837, \"times_seen\": null}, {\"site\": 54, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.3841, \"times_seen\": null}, {\"site\": 54, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.3237, \"times_seen\": null}, {\"site\": 55, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -2.1941, \"times_seen\": null}, {\"site\": 55, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -2.7433, \"times_seen\": null}, {\"site\": 55, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 56, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -2.7355, \"times_seen\": null}, {\"site\": 57, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -0.9319, \"times_seen\": null}, {\"site\": 57, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -2.3902, \"times_seen\": null}, {\"site\": 58, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 58, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -2.9906, \"times_seen\": null}, {\"site\": 58, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": 0.0307, \"times_seen\": null}, {\"site\": 60, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -2.3603, \"times_seen\": null}, {\"site\": 63, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 65, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 66, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 68, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.4954, \"times_seen\": null}, {\"site\": 69, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": -0.1804, \"times_seen\": null}, {\"site\": 71, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": -0.0436, \"times_seen\": null}, {\"site\": 75, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 75, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 76, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0957, \"times_seen\": null}, {\"site\": 77, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0182, \"times_seen\": null}, {\"site\": 77, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.4525, \"times_seen\": null}, {\"site\": 77, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -1.6337, \"times_seen\": null}, {\"site\": 79, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 81, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.1781, \"times_seen\": null}, {\"site\": 81, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 81, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -3.251, \"times_seen\": null}, {\"site\": 83, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.4456, \"times_seen\": null}, {\"site\": 87, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 87, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -1.9226, \"times_seen\": null}, {\"site\": 87, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.3548, \"times_seen\": null}, {\"site\": 88, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -3.002, \"times_seen\": null}, {\"site\": 88, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.2691, \"times_seen\": null}, {\"site\": 89, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.5509, \"times_seen\": null}, {\"site\": 89, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -3.0806, \"times_seen\": null}, {\"site\": 89, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 90, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -1.1825, \"times_seen\": null}, {\"site\": 91, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -3.2479, \"times_seen\": null}, {\"site\": 92, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 95, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 97, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.6425, \"times_seen\": null}, {\"site\": 97, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.4147, \"times_seen\": null}, {\"site\": 98, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.0746, \"times_seen\": null}, {\"site\": 98, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 99, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 99, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.1396, \"times_seen\": null}, {\"site\": 100, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 100, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": -0.4304, \"times_seen\": null}, {\"site\": 101, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 101, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.5467, \"times_seen\": null}, {\"site\": 102, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 103, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 104, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 104, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 105, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 105, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.1019, \"times_seen\": null}, {\"site\": 107, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 107, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -3.0375, \"times_seen\": null}, {\"site\": 108, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 108, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -1.0578, \"times_seen\": null}, {\"site\": 109, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 110, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 115, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -3.2758, \"times_seen\": null}, {\"site\": 116, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -2.9821, \"times_seen\": null}, {\"site\": 116, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.8778, \"times_seen\": null}, {\"site\": 117, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -1.067, \"times_seen\": null}, {\"site\": 117, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -0.835, \"times_seen\": null}, {\"site\": 118, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.481, \"times_seen\": null}, {\"site\": 119, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -2.8939, \"times_seen\": null}, {\"site\": 120, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": 0.3319, \"times_seen\": null}, {\"site\": 121, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -1.6932, \"times_seen\": null}, {\"site\": 125, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.0781, \"times_seen\": null}, {\"site\": 125, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": 0.2259, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": 0.9989, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -1.4896, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -1.743, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.388, \"times_seen\": null}, {\"site\": 127, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -2.9735, \"times_seen\": null}, {\"site\": 127, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 129, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -3.2644, \"times_seen\": null}, {\"site\": 129, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.2294, \"times_seen\": null}, {\"site\": 129, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -3.2541, \"times_seen\": null}, {\"site\": 130, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -2.9703, \"times_seen\": null}, {\"site\": 131, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -3.2642, \"times_seen\": null}, {\"site\": 132, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.5534, \"times_seen\": null}, {\"site\": 133, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 134, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": 0.2867, \"times_seen\": null}, {\"site\": 135, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 140, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 142, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 142, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.8951, \"times_seen\": null}, {\"site\": 142, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 143, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.2116, \"times_seen\": null}, {\"site\": 144, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.2256, \"times_seen\": null}, {\"site\": 145, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 147, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.7731, \"times_seen\": null}, {\"site\": 149, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -2.9301, \"times_seen\": null}, {\"site\": 150, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -3.1878, \"times_seen\": null}, {\"site\": 150, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.2891, \"times_seen\": null}, {\"site\": 153, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.27, \"times_seen\": null}, {\"site\": 154, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0379, \"times_seen\": null}, {\"site\": 155, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 155, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 157, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -2.4732, \"times_seen\": null}, {\"site\": 157, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 160, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.8719, \"times_seen\": null}, {\"site\": 161, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -3.0134, \"times_seen\": null}, {\"site\": 161, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 161, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -3.0054, \"times_seen\": null}, {\"site\": 162, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.1392, \"times_seen\": null}, {\"site\": 163, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.2547, \"times_seen\": null}, {\"site\": 163, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.8997, \"times_seen\": null}, {\"site\": 164, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -3.0021, \"times_seen\": null}, {\"site\": 165, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.3584, \"times_seen\": null}, {\"site\": 168, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -1.0772, \"times_seen\": null}, {\"site\": 168, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.06, \"times_seen\": null}, {\"site\": 170, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 171, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.5502, \"times_seen\": null}, {\"site\": 173, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -2.3457, \"times_seen\": null}, {\"site\": 174, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -3.2847, \"times_seen\": null}, {\"site\": 174, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.3709, \"times_seen\": null}, {\"site\": 175, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -2.3131, \"times_seen\": null}, {\"site\": 177, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -3.2884, \"times_seen\": null}, {\"site\": 177, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -0.3944, \"times_seen\": null}, {\"site\": 178, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 179, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 179, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.2267, \"times_seen\": null}, {\"site\": 180, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 181, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 182, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 183, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 183, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 184, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 184, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 184, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -0.8023, \"times_seen\": null}, {\"site\": 185, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 185, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 186, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 186, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -2.487, \"times_seen\": null}, {\"site\": 187, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 187, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.7, \"times_seen\": null}, {\"site\": 188, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 188, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -3.0012, \"times_seen\": null}, {\"site\": 188, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -1.0815, \"times_seen\": null}, {\"site\": 189, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 189, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -2.9593, \"times_seen\": null}, {\"site\": 190, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 190, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 190, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 191, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 191, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 193, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -2.9276, \"times_seen\": null}, {\"site\": 195, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": -2.8839, \"times_seen\": null}, {\"site\": 196, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": -0.6135, \"times_seen\": null}, {\"site\": 197, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.5056, \"times_seen\": null}, {\"site\": 198, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 199, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -2.2239, \"times_seen\": null}, {\"site\": 200, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.681, \"times_seen\": null}, {\"site\": 201, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 202, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.3132, \"times_seen\": null}, {\"site\": 203, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.2688, \"times_seen\": null}, {\"site\": 204, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.2366, \"times_seen\": null}, {\"site\": 205, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -3.1276, \"times_seen\": null}, {\"site\": 208, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -3.0402, \"times_seen\": null}, {\"site\": 208, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.031, \"times_seen\": null}, {\"site\": 209, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -3.0075, \"times_seen\": null}, {\"site\": 212, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 213, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.3526, \"times_seen\": null}, {\"site\": 214, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 215, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -2.7657, \"times_seen\": null}, {\"site\": 215, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 216, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 216, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0321, \"times_seen\": null}, {\"site\": 217, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 217, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": -1.2951, \"times_seen\": null}, {\"site\": 218, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 219, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -2.4924, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -2.5797, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -0.9401, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -3.2667, \"times_seen\": null}, {\"site\": 221, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -2.5387, \"times_seen\": null}, {\"site\": 221, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 221, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.4872, \"times_seen\": null}, {\"site\": 222, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 222, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.138, \"times_seen\": null}, {\"site\": 223, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 224, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 224, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.0935, \"times_seen\": null}, {\"site\": 224, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -3.0983, \"times_seen\": null}, {\"site\": 226, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": 0.0504, \"times_seen\": null}, {\"site\": 226, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -1.7349, \"times_seen\": null}, {\"site\": 228, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.0682, \"times_seen\": null}, {\"site\": 229, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 230, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -0.229, \"times_seen\": null}, {\"site\": 230, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.0646, \"times_seen\": null}, {\"site\": 232, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -2.8017, \"times_seen\": null}, {\"site\": 234, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 235, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 235, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": 0.0113, \"times_seen\": null}, {\"site\": 235, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.1558, \"times_seen\": null}, {\"site\": 236, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -2.1075, \"times_seen\": null}, {\"site\": 238, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.0438, \"times_seen\": null}, {\"site\": 240, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0181, \"times_seen\": null}, {\"site\": 241, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1266, \"times_seen\": null}, {\"site\": 243, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0263, \"times_seen\": null}, {\"site\": 245, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.3224, \"times_seen\": null}, {\"site\": 248, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 249, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -0.3516, \"times_seen\": null}, {\"site\": 250, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -2.9867, \"times_seen\": null}, {\"site\": 251, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -2.8802, \"times_seen\": null}, {\"site\": 251, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -1.236, \"times_seen\": null}, {\"site\": 252, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 253, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 257, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": -0.0857, \"times_seen\": null}, {\"site\": 257, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0593, \"times_seen\": null}, {\"site\": 258, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -1.6178, \"times_seen\": null}, {\"site\": 259, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 1.1621, \"times_seen\": null}, {\"site\": 261, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": 0.0343, \"times_seen\": null}, {\"site\": 262, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 263, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -3.1313, \"times_seen\": null}, {\"site\": 263, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -2.7898, \"times_seen\": null}, {\"site\": 264, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.5584, \"times_seen\": null}, {\"site\": 264, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -2.6471, \"times_seen\": null}, {\"site\": 265, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 266, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": 0.0884, \"times_seen\": null}, {\"site\": 266, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": 0.7108, \"times_seen\": null}, {\"site\": 267, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.2507, \"times_seen\": null}, {\"site\": 267, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.5835, \"times_seen\": null}, {\"site\": 268, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -1.7877, \"times_seen\": null}, {\"site\": 268, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.1829, \"times_seen\": null}, {\"site\": 269, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.2025, \"times_seen\": null}, {\"site\": 269, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -3.2083, \"times_seen\": null}, {\"site\": 270, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -1.3479, \"times_seen\": null}, {\"site\": 270, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.7758, \"times_seen\": null}, {\"site\": 272, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -2.9369, \"times_seen\": null}, {\"site\": 272, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -0.5865, \"times_seen\": null}, {\"site\": 272, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -0.1679, \"times_seen\": null}, {\"site\": 274, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 274, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": -0.9872, \"times_seen\": null}, {\"site\": 276, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -1.0005, \"times_seen\": null}, {\"site\": 276, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -2.5458, \"times_seen\": null}, {\"site\": 277, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.92, \"times_seen\": null}, {\"site\": 278, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -1.0849, \"times_seen\": null}, {\"site\": 280, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 280, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 280, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.4582, \"times_seen\": null}, {\"site\": 282, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -2.9946, \"times_seen\": null}, {\"site\": 283, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.3002, \"times_seen\": null}, {\"site\": 284, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.7471, \"times_seen\": null}, {\"site\": 286, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -3.2617, \"times_seen\": null}, {\"site\": 286, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -2.3127, \"times_seen\": null}, {\"site\": 287, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 287, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -1.8474, \"times_seen\": null}, {\"site\": 287, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -1.9768, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.8456, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.9996, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 289, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -2.9013, \"times_seen\": null}, {\"site\": 291, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -2.6269, \"times_seen\": null}, {\"site\": 291, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -3.032, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -2.9899, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -2.4632, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -3.2361, \"times_seen\": null}, {\"site\": 293, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -3.268, \"times_seen\": null}, {\"site\": 293, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -2.318, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -2.9573, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -1.8098, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -3.128, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.5392, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -1.1533, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.9724, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.5601, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -1.2613, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -2.7906, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -1.4359, \"times_seen\": null}, {\"site\": 298, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -2.6362, \"times_seen\": null}, {\"site\": 298, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -2.7258, \"times_seen\": null}, {\"site\": 299, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -2.4022, \"times_seen\": null}, {\"site\": 300, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.1477, \"times_seen\": null}, {\"site\": 300, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.6929, \"times_seen\": null}, {\"site\": 301, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": -3.2048, \"times_seen\": null}, {\"site\": 302, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -1.1989, \"times_seen\": null}, {\"site\": 302, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 302, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -2.6361, \"times_seen\": null}, {\"site\": 303, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -2.4926, \"times_seen\": null}, {\"site\": 304, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 305, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -2.9941, \"times_seen\": null}, {\"site\": 306, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -3.0868, \"times_seen\": null}, {\"site\": 307, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -2.9005, \"times_seen\": null}, {\"site\": 307, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -2.8108, \"times_seen\": null}, {\"site\": 308, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.4876, \"times_seen\": null}, {\"site\": 308, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -1.6802, \"times_seen\": null}, {\"site\": 308, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -3.1353, \"times_seen\": null}, {\"site\": 309, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -0.0493, \"times_seen\": null}, {\"site\": 309, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -1.8036, \"times_seen\": null}, {\"site\": 309, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -2.144, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.7744, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -0.4934, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.4895, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.942, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.6642, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.0463, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -3.0359, \"times_seen\": null}, {\"site\": 311, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -1.2648, \"times_seen\": null}, {\"site\": 311, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.3253, \"times_seen\": null}, {\"site\": 312, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -2.5656, \"times_seen\": null}, {\"site\": 312, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -2.5653, \"times_seen\": null}, {\"site\": 312, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -2.99, \"times_seen\": null}, {\"site\": 313, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.2211, \"times_seen\": null}, {\"site\": 313, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.8517, \"times_seen\": null}, {\"site\": 313, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -2.6799, \"times_seen\": null}, {\"site\": 314, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -2.3119, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -3.1273, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.9726, \"times_seen\": null}, {\"site\": 317, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -1.9108, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.9236, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.8881, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.8281, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -3.13, \"times_seen\": null}, {\"site\": 321, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -2.9699, \"times_seen\": null}, {\"site\": 321, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.3572, \"times_seen\": null}, {\"site\": 323, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -3.2614, \"times_seen\": null}, {\"site\": 323, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -3.1291, \"times_seen\": null}, {\"site\": 324, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -1.6056, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.9665, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.6845, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -1.2725, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.0587, \"times_seen\": null}, {\"site\": 326, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -3.0183, \"times_seen\": null}, {\"site\": 326, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 327, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -2.5724, \"times_seen\": null}, {\"site\": 329, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -0.3912, \"times_seen\": null}, {\"site\": 329, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -1.7635, \"times_seen\": null}, {\"site\": 329, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": 0.087, \"times_seen\": null}, {\"site\": 331, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -1.0289, \"times_seen\": null}, {\"site\": 333, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -1.984, \"times_seen\": null}, {\"site\": 333, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -2.0218, \"times_seen\": null}, {\"site\": 333, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -2.8487, \"times_seen\": null}, {\"site\": 334, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.4448, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.8826, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.9682, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.6032, \"times_seen\": null}, {\"site\": 336, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 337, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 337, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -2.9882, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -3.0848, \"times_seen\": null}, {\"site\": 339, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 339, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.879, \"times_seen\": null}, {\"site\": 340, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 340, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -3.2684, \"times_seen\": null}, {\"site\": 340, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -2.0563, \"times_seen\": null}, {\"site\": 341, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 341, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -2.5035, \"times_seen\": null}, {\"site\": 342, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 343, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 343, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -1.4097, \"times_seen\": null}, {\"site\": 345, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 345, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.6967, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.9226, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.9673, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 347, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -1.3334, \"times_seen\": null}, {\"site\": 347, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 347, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.9322, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -2.1682, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -2.0452, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -3.2547, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -2.7372, \"times_seen\": null}, {\"site\": 349, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -2.7571, \"times_seen\": null}, {\"site\": 349, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 349, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 350, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -2.7008, \"times_seen\": null}, {\"site\": 350, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -0.759, \"times_seen\": null}, {\"site\": 351, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.3727, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -3.0142, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.9914, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.6016, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.7663, \"times_seen\": null}, {\"site\": 353, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -2.6337, \"times_seen\": null}, {\"site\": 354, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -1.6586, \"times_seen\": null}, {\"site\": 355, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -1.5589, \"times_seen\": null}, {\"site\": 355, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -3.2049, \"times_seen\": null}, {\"site\": 356, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.9389, \"times_seen\": null}, {\"site\": 357, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.1294, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.2653, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.1037, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.8591, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.9714, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 359, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 359, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -2.8474, \"times_seen\": null}, {\"site\": 360, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 361, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 361, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.4825, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.6021, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 363, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 363, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -2.9689, \"times_seen\": null}, {\"site\": 364, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 365, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 365, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -3.0169, \"times_seen\": null}, {\"site\": 365, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -0.29, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -2.996, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -0.7909, \"times_seen\": null}, {\"site\": 367, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 367, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": -2.7039, \"times_seen\": null}, {\"site\": 368, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -3.1689, \"times_seen\": null}, {\"site\": 370, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.21, \"times_seen\": null}, {\"site\": 371, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": 0.1515, \"times_seen\": null}, {\"site\": 371, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -2.4492, \"times_seen\": null}, {\"site\": 371, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -1.203, \"times_seen\": null}, {\"site\": 373, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -2.9734, \"times_seen\": null}, {\"site\": 374, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 374, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -0.67, \"times_seen\": null}, {\"site\": 375, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 375, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.9931, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.1907, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -3.2038, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -3.2034, \"times_seen\": null}, {\"site\": 377, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -2.7142, \"times_seen\": null}, {\"site\": 377, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 378, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 378, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 379, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 379, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -1.5909, \"times_seen\": null}, {\"site\": 380, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 380, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -1.8667, \"times_seen\": null}, {\"site\": 380, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -1.7595, \"times_seen\": null}, {\"site\": 381, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 382, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 382, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 383, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 383, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -0.8204, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -2.9459, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -3.2651, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -3.036, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -2.9934, \"times_seen\": null}, {\"site\": 385, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 385, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -1.1864, \"times_seen\": null}, {\"site\": 385, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 386, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 386, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -2.689, \"times_seen\": null}, {\"site\": 386, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.8675, \"times_seen\": null}, {\"site\": 387, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 387, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -3.2571, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -2.9487, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -3.0135, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -3.0351, \"times_seen\": null}, {\"site\": 389, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 389, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.8995, \"times_seen\": null}, {\"site\": 390, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 390, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -2.9133, \"times_seen\": null}, {\"site\": 391, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 392, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 392, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 393, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -2.9509, \"times_seen\": null}, {\"site\": 393, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 393, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.0178, \"times_seen\": null}, {\"site\": 394, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 394, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 395, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 395, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -2.8109, \"times_seen\": null}, {\"site\": 395, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -3.2346, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -2.4874, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -3.131, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -3.0019, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.7856, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -1.7314, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -1.5979, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.223, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": 1.4893, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": 0.0417, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -2.2593, \"times_seen\": null}, {\"site\": 399, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 399, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -3.0507, \"times_seen\": null}, {\"site\": 400, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 400, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -2.3165, \"times_seen\": null}, {\"site\": 401, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 401, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 401, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -2.8796, \"times_seen\": null}, {\"site\": 402, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.9827, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.6011, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.6288, \"times_seen\": null}, {\"site\": 404, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 404, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -0.0389, \"times_seen\": null}, {\"site\": 405, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 406, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 407, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 407, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -1.5536, \"times_seen\": null}, {\"site\": 407, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -2.8579, \"times_seen\": null}, {\"site\": 408, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 408, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -0.7117, \"times_seen\": null}, {\"site\": 408, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.8117, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -3.0028, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.8733, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -1.8136, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.8789, \"times_seen\": null}, {\"site\": 410, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.9652, \"times_seen\": null}, {\"site\": 410, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 411, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -1.4209, \"times_seen\": null}, {\"site\": 411, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 412, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -3.0001, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.8403, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -1.6747, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.3923, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.1237, \"times_seen\": null}, {\"site\": 414, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -2.7518, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -1.9397, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -2.8834, \"times_seen\": null}, {\"site\": 416, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -3.2606, \"times_seen\": null}, {\"site\": 416, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -3.0208, \"times_seen\": null}, {\"site\": 416, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -3.054, \"times_seen\": null}, {\"site\": 417, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -1.248, \"times_seen\": null}, {\"site\": 418, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 418, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -3.0792, \"times_seen\": null}, {\"site\": 418, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -0.7687, \"times_seen\": null}, {\"site\": 419, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 419, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -1.3291, \"times_seen\": null}, {\"site\": 419, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -3.1359, \"times_seen\": null}, {\"site\": 420, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 420, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -2.8029, \"times_seen\": null}, {\"site\": 421, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -1.7255, \"times_seen\": null}, {\"site\": 421, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -1.4729, \"times_seen\": null}, {\"site\": 423, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -2.878, \"times_seen\": null}, {\"site\": 423, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 424, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.5455, \"times_seen\": null}, {\"site\": 425, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -2.5958, \"times_seen\": null}, {\"site\": 426, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.3302, \"times_seen\": null}, {\"site\": 426, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.9588, \"times_seen\": null}, {\"site\": 428, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -3.1899, \"times_seen\": null}, {\"site\": 428, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -2.9501, \"times_seen\": null}, {\"site\": 428, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -3.0255, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -0.53, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -2.5367, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -2.6833, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -3.0191, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -0.8518, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -2.9112, \"times_seen\": null}, {\"site\": 431, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.9182, \"times_seen\": null}, {\"site\": 432, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -3.0514, \"times_seen\": null}, {\"site\": 432, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 433, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -3.1203, \"times_seen\": null}, {\"site\": 433, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -3.0454, \"times_seen\": null}, {\"site\": 433, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -2.542, \"times_seen\": null}, {\"site\": 434, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.9261, \"times_seen\": null}, {\"site\": 435, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.9463, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 437, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 438, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 446, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 447, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.1636, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.5122, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -0.4405, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.1395, \"times_seen\": null}, {\"site\": 450, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.1241, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.2549, \"times_seen\": null}, {\"site\": 452, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 452, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -0.6037, \"times_seen\": null}, {\"site\": 453, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 453, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -3.2691, \"times_seen\": null}, {\"site\": 453, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -2.5998, \"times_seen\": null}, {\"site\": 454, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -3.0652, \"times_seen\": null}, {\"site\": 454, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -2.1814, \"times_seen\": null}, {\"site\": 454, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": 0.0537, \"times_seen\": null}, {\"site\": 456, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2341, \"times_seen\": null}, {\"site\": 458, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -2.9417, \"times_seen\": null}, {\"site\": 458, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 458, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 459, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -1.773, \"times_seen\": null}, {\"site\": 460, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -3.2747, \"times_seen\": null}, {\"site\": 461, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -3.2776, \"times_seen\": null}, {\"site\": 463, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -3.1059, \"times_seen\": null}, {\"site\": 463, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -3.0058, \"times_seen\": null}, {\"site\": 464, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.9555, \"times_seen\": null}, {\"site\": 465, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -1.9626, \"times_seen\": null}, {\"site\": 465, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.5777, \"times_seen\": null}, {\"site\": 466, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -2.7969, \"times_seen\": null}, {\"site\": 466, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -1.23, \"times_seen\": null}, {\"site\": 469, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -0.5576, \"times_seen\": null}, {\"site\": 471, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -0.8613, \"times_seen\": null}, {\"site\": 473, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -2.9062, \"times_seen\": null}, {\"site\": 474, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.4453, \"times_seen\": null}, {\"site\": 476, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.7712, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.9991, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.5488, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.9173, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.9774, \"times_seen\": null}, {\"site\": 478, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 479, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -3.0998, \"times_seen\": null}, {\"site\": 483, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": -0.1748, \"times_seen\": null}, {\"site\": 484, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.7516, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.951, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": 0.2729, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.9789, \"times_seen\": null}, {\"site\": 487, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 487, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 488, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 488, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -3.2591, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -1.4113, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -2.4571, \"times_seen\": null}, {\"site\": 492, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 492, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.3157, \"times_seen\": null}, {\"site\": 492, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.2545, \"times_seen\": null}, {\"site\": 493, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -3.0079, \"times_seen\": null}, {\"site\": 494, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 494, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 502, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 503, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -2.1871, \"times_seen\": null}, {\"site\": 503, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -2.8228, \"times_seen\": null}, {\"site\": 504, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 505, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 505, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -2.3822, \"times_seen\": null}, {\"site\": 506, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 506, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -3.2089, \"times_seen\": null}, {\"site\": 507, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 507, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.4638, \"times_seen\": null}, {\"site\": 507, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.8298, \"times_seen\": null}, {\"site\": 508, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 508, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -3.0986, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.7182, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.9858, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.8415, \"times_seen\": null}, {\"site\": 510, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 510, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.8948, \"times_seen\": null}, {\"site\": 511, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 511, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -3.1416, \"times_seen\": null}, {\"site\": 511, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -2.608, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.9644, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -3.2839, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.6904, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.3583, \"times_seen\": null}, {\"site\": 513, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.8143, \"times_seen\": null}, {\"site\": 515, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.5171, \"times_seen\": null}, {\"site\": 516, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -1.0538, \"times_seen\": null}, {\"site\": 517, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -2.0683, \"times_seen\": null}, {\"site\": 519, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.36, \"times_seen\": null}, {\"site\": 520, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -2.1929, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -3.2398, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -0.1108, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -2.3718, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -0.9578, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -2.8275, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -3.0875, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -2.9129, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -2.9482, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -1.8801, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -3.1198, \"times_seen\": null}, {\"site\": 523, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -2.4069, \"times_seen\": null}, {\"site\": 524, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -2.6649, \"times_seen\": null}, {\"site\": 524, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -2.5665, \"times_seen\": null}, {\"site\": 525, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 525, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.7343, \"times_seen\": null}, {\"site\": 525, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -2.9407, \"times_seen\": null}, {\"site\": 527, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -3.261, \"times_seen\": null}, {\"site\": 527, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -2.6451, \"times_seen\": null}, {\"site\": 527, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -2.6907, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -3.0131, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -1.7137, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -1.218, \"times_seen\": null}, {\"site\": 529, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -2.1012, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -3.1267, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -3.2559, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -2.5095, \"times_seen\": null}, {\"site\": 531, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 531, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -1.9197, \"times_seen\": null}, {\"site\": 531, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -2.5316, \"times_seen\": null}, {\"site\": 532, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 532, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -1.7736, \"times_seen\": null}, {\"site\": 532, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -2.633, \"times_seen\": null}, {\"site\": 533, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 533, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -3.0933, \"times_seen\": null}, {\"site\": 534, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -2.101, \"times_seen\": null}, {\"site\": 534, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.9372, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -3.0562, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.9066, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -3.233, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.4097, \"times_seen\": null}, {\"site\": 536, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 536, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -2.809, \"times_seen\": null}, {\"site\": 537, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.7164, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -3.0898, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.6257, \"times_seen\": null}, {\"site\": 539, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.4756, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -0.0019, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.6852, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.884, \"times_seen\": null}, {\"site\": 541, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 541, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -0.4128, \"times_seen\": null}, {\"site\": 542, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.9755, \"times_seen\": null}, {\"site\": 542, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.7771, \"times_seen\": null}, {\"site\": 543, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": -2.9377, \"times_seen\": null}, {\"site\": 544, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -2.6726, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.9917, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.9874, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -3.0095, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.7874, \"times_seen\": null}, {\"site\": 546, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -1.0964, \"times_seen\": null}, {\"site\": 547, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 547, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.9819, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -2.9188, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -3.0603, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -2.8877, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -0.1976, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.9185, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -1.9556, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -3.2497, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -3.0461, \"times_seen\": null}, {\"site\": 550, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -2.0618, \"times_seen\": null}, {\"site\": 551, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 551, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -2.7917, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -3.0124, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -3.1316, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -1.6653, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.2885, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.9281, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.5397, \"times_seen\": null}, {\"site\": 555, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -2.0148, \"times_seen\": null}, {\"site\": 555, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.385, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -1.1, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -1.2662, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.924, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -0.4951, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.585, \"times_seen\": null}, {\"site\": 559, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -3.1555, \"times_seen\": null}, {\"site\": 559, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -3.0884, \"times_seen\": null}, {\"site\": 560, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.4618, \"times_seen\": null}, {\"site\": 561, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -0.38, \"times_seen\": null}, {\"site\": 561, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 562, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -2.3316, \"times_seen\": null}, {\"site\": 563, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -2.9434, \"times_seen\": null}, {\"site\": 563, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -0.5665, \"times_seen\": null}, {\"site\": 563, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -2.3366, \"times_seen\": null}, {\"site\": 564, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.4161, \"times_seen\": null}, {\"site\": 565, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 565, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -1.5973, \"times_seen\": null}, {\"site\": 565, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -3.0982, \"times_seen\": null}, {\"site\": 566, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -1.5911, \"times_seen\": null}, {\"site\": 568, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -2.0259, \"times_seen\": null}, {\"site\": 570, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.5474, \"times_seen\": null}, {\"site\": 570, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.3033, \"times_seen\": null}, {\"site\": 570, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.4348, \"times_seen\": null}, {\"site\": 572, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -3.0047, \"times_seen\": null}, {\"site\": 572, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": 0.7078, \"times_seen\": null}, {\"site\": 574, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.8795, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -3.0225, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -3.085, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -2.8685, \"times_seen\": null}, {\"site\": 576, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -1.6729, \"times_seen\": null}, {\"site\": 576, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -2.1658, \"times_seen\": null}, {\"site\": 576, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -2.6607, \"times_seen\": null}, {\"site\": 577, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -2.4574, \"times_seen\": null}, {\"site\": 578, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": 0.0867, \"times_seen\": null}, {\"site\": 578, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": -0.8684, \"times_seen\": null}, {\"site\": 580, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.4807, \"times_seen\": null}, {\"site\": 580, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 581, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 581, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -3.0759, \"times_seen\": null}, {\"site\": 581, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 582, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 582, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -3.0671, \"times_seen\": null}, {\"site\": 582, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -1.8692, \"times_seen\": null}, {\"site\": 583, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.6565, \"times_seen\": null}, {\"site\": 583, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -3.0571, \"times_seen\": null}, {\"site\": 583, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.7541, \"times_seen\": null}, {\"site\": 584, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 586, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.6176, \"times_seen\": null}, {\"site\": 586, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.9764, \"times_seen\": null}, {\"site\": 586, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.5191, \"times_seen\": null}, {\"site\": 587, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9546, \"times_seen\": null}, {\"site\": 587, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 589, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 589, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.9925, \"times_seen\": null}, {\"site\": 590, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -3.1088, \"times_seen\": null}, {\"site\": 590, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.8569, \"times_seen\": null}, {\"site\": 593, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -2.9489, \"times_seen\": null}, {\"site\": 594, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 594, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -3.0615, \"times_seen\": null}, {\"site\": 594, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -2.8088, \"times_seen\": null}, {\"site\": 595, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 595, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 595, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -3.2609, \"times_seen\": null}, {\"site\": 596, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 596, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.6075, \"times_seen\": null}, {\"site\": 596, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 597, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 597, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -3.0462, \"times_seen\": null}, {\"site\": 597, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.9775, \"times_seen\": null}, {\"site\": 598, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -3.237, \"times_seen\": null}, {\"site\": 598, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -2.1284, \"times_seen\": null}, {\"site\": 599, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -2.3607, \"times_seen\": null}, {\"site\": 599, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -1.7296, \"times_seen\": null}, {\"site\": 599, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -3.0817, \"times_seen\": null}, {\"site\": 600, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.8372, \"times_seen\": null}, {\"site\": 602, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -3.1345, \"times_seen\": null}, {\"site\": 602, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 602, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 603, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 603, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.133, \"times_seen\": null}, {\"site\": 604, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.3317, \"times_seen\": null}, {\"site\": 605, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -1.4881, \"times_seen\": null}, {\"site\": 605, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -2.9968, \"times_seen\": null}, {\"site\": 606, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.843, \"times_seen\": null}, {\"site\": 606, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.0465, \"times_seen\": null}, {\"site\": 607, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -3.0487, \"times_seen\": null}, {\"site\": 607, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -3.2443, \"times_seen\": null}, {\"site\": 607, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -2.9958, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9547, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.7929, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9456, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9307, \"times_seen\": null}, {\"site\": 611, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.8327, \"times_seen\": null}, {\"site\": 612, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.8497, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.5949, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -1.2614, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -3.132, \"times_seen\": null}, {\"site\": 616, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -1.4132, \"times_seen\": null}, {\"site\": 617, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 617, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -2.1861, \"times_seen\": null}, {\"site\": 618, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 618, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.3843, \"times_seen\": null}, {\"site\": 619, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -2.2694, \"times_seen\": null}, {\"site\": 620, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -1.736, \"times_seen\": null}, {\"site\": 620, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -1.2151, \"times_seen\": null}, {\"site\": 621, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 621, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": -2.6612, \"times_seen\": null}, {\"site\": 622, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 623, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 624, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -1.7134, \"times_seen\": null}, {\"site\": 625, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -1.9116, \"times_seen\": null}, {\"site\": 625, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -2.8236, \"times_seen\": null}, {\"site\": 626, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 627, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -2.6515, \"times_seen\": null}, {\"site\": 627, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -0.6732, \"times_seen\": null}, {\"site\": 628, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -2.5612, \"times_seen\": null}, {\"site\": 629, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.5555, \"times_seen\": null}, {\"site\": 630, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -3.2461, \"times_seen\": null}, {\"site\": 630, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 631, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.6942, \"times_seen\": null}, {\"site\": 632, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": -0.0971, \"times_seen\": null}, {\"site\": 633, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 633, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -3.0175, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -2.2629, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -3.2586, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -1.5063, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.5058, \"times_seen\": null}, {\"site\": 637, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 638, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.6966, \"times_seen\": null}, {\"site\": 639, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.2404, \"times_seen\": null}, {\"site\": 640, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 641, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -1.2621, \"times_seen\": null}, {\"site\": 641, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 641, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -2.1822, \"times_seen\": null}, {\"site\": 642, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.5747, \"times_seen\": null}, {\"site\": 642, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -0.1741, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -3.2615, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -3.1376, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.739, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.6423, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -3.1327, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.2135, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.922, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.479, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.7214, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.8815, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.8995, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.5692, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -1.9246, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.9784, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.8907, \"times_seen\": null}, {\"site\": 648, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -1.796, \"times_seen\": null}, {\"site\": 648, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 648, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -2.9986, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.9974, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.918, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.6322, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.8331, \"times_seen\": null}, {\"site\": 650, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 650, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.8205, \"times_seen\": null}, {\"site\": 650, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 651, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 651, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": 0.1923, \"times_seen\": null}, {\"site\": 652, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 653, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 654, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 654, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.8364, \"times_seen\": null}, {\"site\": 655, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 655, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -0.4271, \"times_seen\": null}, {\"site\": 656, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 657, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -1.5896, \"times_seen\": null}, {\"site\": 657, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 657, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.4082, \"times_seen\": null}, {\"site\": 658, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -3.087, \"times_seen\": null}, {\"site\": 658, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 659, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -3.1855, \"times_seen\": null}, {\"site\": 659, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 660, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 660, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -1.7556, \"times_seen\": null}, {\"site\": 660, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -3.125, \"times_seen\": null}, {\"site\": 661, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 661, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.3552, \"times_seen\": null}, {\"site\": 661, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.2529, \"times_seen\": null}, {\"site\": 662, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 662, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -2.1018, \"times_seen\": null}, {\"site\": 662, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -1.5219, \"times_seen\": null}, {\"site\": 663, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -2.7785, \"times_seen\": null}, {\"site\": 664, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -1.7201, \"times_seen\": null}, {\"site\": 666, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -0.7519, \"times_seen\": null}, {\"site\": 666, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -3.2764, \"times_seen\": null}, {\"site\": 668, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 668, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.9839, \"times_seen\": null}, {\"site\": 669, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 669, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -2.7085, \"times_seen\": null}, {\"site\": 670, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.1489, \"times_seen\": null}, {\"site\": 671, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -2.2944, \"times_seen\": null}, {\"site\": 671, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -3.0437, \"times_seen\": null}, {\"site\": 672, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -1.5438, \"times_seen\": null}, {\"site\": 672, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -0.3102, \"times_seen\": null}, {\"site\": 672, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -3.2213, \"times_seen\": null}, {\"site\": 674, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.2997, \"times_seen\": null}, {\"site\": 679, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.7621, \"times_seen\": null}, {\"site\": 680, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.0362, \"times_seen\": null}, {\"site\": 680, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.019, \"times_seen\": null}, {\"site\": 681, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": -0.2085, \"times_seen\": null}, {\"site\": 682, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": -0.0979, \"times_seen\": null}, {\"site\": 684, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.9512, \"times_seen\": null}, {\"site\": 685, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -2.9234, \"times_seen\": null}, {\"site\": 686, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 686, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -0.173, \"times_seen\": null}, {\"site\": 687, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 689, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -3.2584, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.3379, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.3074, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -3.066, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -3.0186, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -3.2784, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 693, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 693, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.3019, \"times_seen\": null}, {\"site\": 694, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 694, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -2.6723, \"times_seen\": null}, {\"site\": 695, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -1.3615, \"times_seen\": null}, {\"site\": 696, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -3.0141, \"times_seen\": null}, {\"site\": 696, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -0.7797, \"times_seen\": null}, {\"site\": 697, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.3439, \"times_seen\": null}, {\"site\": 697, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -3.0251, \"times_seen\": null}, {\"site\": 699, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 701, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": -0.8183, \"times_seen\": null}, {\"site\": 702, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -2.9829, \"times_seen\": null}, {\"site\": 703, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -2.0658, \"times_seen\": null}, {\"site\": 703, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -2.8496, \"times_seen\": null}, {\"site\": 704, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.2896, \"times_seen\": null}, {\"site\": 705, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 705, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.4402, \"times_seen\": null}, {\"site\": 705, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.8747, \"times_seen\": null}, {\"site\": 706, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -2.9375, \"times_seen\": null}, {\"site\": 707, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 708, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -0.8443, \"times_seen\": null}, {\"site\": 708, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -2.9811, \"times_seen\": null}, {\"site\": 709, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -3.249, \"times_seen\": null}, {\"site\": 711, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -3.2101, \"times_seen\": null}, {\"site\": 711, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -2.9601, \"times_seen\": null}, {\"site\": 712, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 713, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.874, \"times_seen\": null}, {\"site\": 714, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -1.1916, \"times_seen\": null}, {\"site\": 714, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -3.1123, \"times_seen\": null}, {\"site\": 714, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.0513, \"times_seen\": null}, {\"site\": 715, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -2.8163, \"times_seen\": null}, {\"site\": 715, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -3.1152, \"times_seen\": null}, {\"site\": 715, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 716, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 717, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 717, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -2.6514, \"times_seen\": null}, {\"site\": 717, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -3.0739, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.482, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -1.6494, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.2213, \"times_seen\": null}, {\"site\": 719, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -1.8183, \"times_seen\": null}, {\"site\": 719, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -2.9973, \"times_seen\": null}, {\"site\": 719, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -2.8552, \"times_seen\": null}, {\"site\": 720, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -0.2352, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -2.9082, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -3.0518, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -3.1332, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -2.8455, \"times_seen\": null}, {\"site\": 723, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": -2.682, \"times_seen\": null}, {\"site\": 724, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -2.2196, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -2.4798, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -2.37, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -1.6758, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -0.7129, \"times_seen\": null}, {\"site\": 726, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 726, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 726, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.8622, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": 0.4189, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.1244, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -1.0604, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.4419, \"times_seen\": null}, {\"site\": 728, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 728, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -2.606, \"times_seen\": null}, {\"site\": 728, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 729, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 729, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 729, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": -2.9597, \"times_seen\": null}, {\"site\": 730, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 730, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -3.1325, \"times_seen\": null}, {\"site\": 730, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 731, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 731, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -2.9745, \"times_seen\": null}, {\"site\": 732, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 732, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -2.7322, \"times_seen\": null}, {\"site\": 732, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": 0.6738, \"times_seen\": null}, {\"site\": 733, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -1.6969, \"times_seen\": null}, {\"site\": 733, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -2.9548, \"times_seen\": null}, {\"site\": 735, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.9813, \"times_seen\": null}, {\"site\": 735, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.9196, \"times_seen\": null}, {\"site\": 735, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 737, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.5015, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -1.5617, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -3.0936, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -0.6647, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -3.0343, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -2.8525, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -3.0053, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -3.052, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -2.6502, \"times_seen\": null}, {\"site\": 741, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -2.6347, \"times_seen\": null}, {\"site\": 741, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 741, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": 0.4254, \"times_seen\": null}, {\"site\": 742, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 742, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -1.1698, \"times_seen\": null}, {\"site\": 743, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 744, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -2.9623, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.4818, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.1913, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.0745, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.9607, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.0024, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.8875, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 747, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 748, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 749, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 749, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.0322, \"times_seen\": null}, {\"site\": 750, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 750, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -2.9731, \"times_seen\": null}, {\"site\": 751, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.6948, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.9599, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -3.234, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": 0.4155, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -3.0014, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.2583, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.0683, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -0.7486, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -3.1031, \"times_seen\": null}, {\"site\": 754, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.4519, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.919, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -3.0579, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.6628, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.8402, \"times_seen\": null}, {\"site\": 759, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -1.8736, \"times_seen\": null}, {\"site\": 759, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -0.5475, \"times_seen\": null}, {\"site\": 762, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -2.6327, \"times_seen\": null}, {\"site\": 762, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -1.1381, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -3.2893, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -2.8309, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -3.2678, \"times_seen\": null}, {\"site\": 765, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.6456, \"times_seen\": null}, {\"site\": 766, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -2.8225, \"times_seen\": null}, {\"site\": 768, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9716, \"times_seen\": null}, {\"site\": 768, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.493, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -2.9508, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -1.329, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": 0.5283, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -3.2891, \"times_seen\": null}, {\"site\": 771, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -1.5265, \"times_seen\": null}, {\"site\": 771, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 771, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.9984, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.2599, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.568, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.4226, \"times_seen\": null}, {\"site\": 773, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 776, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -3.2663, \"times_seen\": null}, {\"site\": 777, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.576, \"times_seen\": null}, {\"site\": 777, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -1.6764, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.0729, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.8674, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.9742, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.6866, \"times_seen\": null}, {\"site\": 779, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.6266, \"times_seen\": null}, {\"site\": 779, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.92, \"times_seen\": null}, {\"site\": 782, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 782, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.3291, \"times_seen\": null}, {\"site\": 783, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.2916, \"times_seen\": null}, {\"site\": 787, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 787, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -2.6097, \"times_seen\": null}, {\"site\": 788, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.6799, \"times_seen\": null}, {\"site\": 788, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.0459, \"times_seen\": null}, {\"site\": 789, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 789, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": 0.6623, \"times_seen\": null}, {\"site\": 789, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.9385, \"times_seen\": null}, {\"site\": 790, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 791, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 791, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 793, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -2.8316, \"times_seen\": null}, {\"site\": 795, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -2.8864, \"times_seen\": null}, {\"site\": 796, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 798, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 798, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -3.0358, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -2.0436, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -3.1372, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -1.5288, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -0.9458, \"times_seen\": null}, {\"site\": 800, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -2.8923, \"times_seen\": null}, {\"site\": 801, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -1.5857, \"times_seen\": null}, {\"site\": 801, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 802, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -3.1385, \"times_seen\": null}, {\"site\": 802, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -3.15, \"times_seen\": null}, {\"site\": 802, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 803, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -2.1869, \"times_seen\": null}, {\"site\": 803, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -2.8206, \"times_seen\": null}, {\"site\": 803, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -2.3767, \"times_seen\": null}, {\"site\": 804, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 804, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -1.7397, \"times_seen\": null}, {\"site\": 806, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -1.2617, \"times_seen\": null}, {\"site\": 808, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -3.1474, \"times_seen\": null}, {\"site\": 811, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 812, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -3.0625, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.4196, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.9671, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.4335, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.9258, \"times_seen\": null}, {\"site\": 814, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": -2.0337, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.803, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.02, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -0.2899, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -2.8965, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -3.1856, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.2359, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.6892, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.9667, \"times_seen\": null}, {\"site\": 817, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 817, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.0701, \"times_seen\": null}, {\"site\": 817, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.7805, \"times_seen\": null}, {\"site\": 818, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.0771, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.2833, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.8673, \"times_seen\": null}, {\"site\": 820, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 820, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -3.146, \"times_seen\": null}, {\"site\": 820, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -3.0631, \"times_seen\": null}, {\"site\": 821, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 821, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -3.0041, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.9509, \"times_seen\": null}, {\"site\": 823, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 823, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -1.6687, \"times_seen\": null}, {\"site\": 824, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 824, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -1.2831, \"times_seen\": null}, {\"site\": 825, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 825, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": -1.3233, \"times_seen\": null}, {\"site\": 826, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 827, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 828, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -1.3054, \"times_seen\": null}, {\"site\": 828, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 828, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -0.1246, \"times_seen\": null}, {\"site\": 829, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 829, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -2.6684, \"times_seen\": null}, {\"site\": 829, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -1.0359, \"times_seen\": null}, {\"site\": 830, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 831, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 831, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -0.9074, \"times_seen\": null}, {\"site\": 832, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -2.0011, \"times_seen\": null}, {\"site\": 832, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 832, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -1.8672, \"times_seen\": null}, {\"site\": 833, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 834, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -2.8644, \"times_seen\": null}, {\"site\": 834, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 835, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -2.4752, \"times_seen\": null}, {\"site\": 835, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 836, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 836, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.6005, \"times_seen\": null}, {\"site\": 837, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 837, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -1.6807, \"times_seen\": null}, {\"site\": 838, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 839, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -3.0653, \"times_seen\": null}, {\"site\": 839, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 839, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.7771, \"times_seen\": null}, {\"site\": 840, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 840, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -3.2587, \"times_seen\": null}, {\"site\": 840, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -3.0689, \"times_seen\": null}, {\"site\": 843, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.7207, \"times_seen\": null}, {\"site\": 844, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.9387, \"times_seen\": null}, {\"site\": 846, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.5052, \"times_seen\": null}, {\"site\": 846, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -3.1951, \"times_seen\": null}, {\"site\": 847, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -3.2539, \"times_seen\": null}, {\"site\": 847, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -2.5485, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.9615, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.5732, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.4251, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.5641, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 849, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -1.3309, \"times_seen\": null}, {\"site\": 850, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -2.661, \"times_seen\": null}, {\"site\": 850, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -1.5723, \"times_seen\": null}, {\"site\": 851, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 852, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -1.965, \"times_seen\": null}, {\"site\": 852, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -2.4708, \"times_seen\": null}, {\"site\": 854, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -3.0382, \"times_seen\": null}, {\"site\": 854, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -3.0362, \"times_seen\": null}, {\"site\": 857, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -2.9421, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -2.1524, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -3.2746, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -1.6898, \"times_seen\": null}, {\"site\": 861, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 861, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.7403, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.9684, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -1.8793, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.3348, \"times_seen\": null}, {\"site\": 863, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -2.0678, \"times_seen\": null}, {\"site\": 864, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 864, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 864, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -2.9937, \"times_seen\": null}, {\"site\": 865, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -2.9627, \"times_seen\": null}, {\"site\": 865, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 866, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 866, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.1256, \"times_seen\": null}, {\"site\": 866, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.6846, \"times_seen\": null}, {\"site\": 867, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 867, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -3.029, \"times_seen\": null}, {\"site\": 867, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -1.3361, \"times_seen\": null}, {\"site\": 868, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -2.4325, \"times_seen\": null}, {\"site\": 868, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.963, \"times_seen\": null}, {\"site\": 868, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.1637, \"times_seen\": null}, {\"site\": 870, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -3.2859, \"times_seen\": null}, {\"site\": 870, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.3176, \"times_seen\": null}, {\"site\": 870, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -3.0674, \"times_seen\": null}, {\"site\": 871, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.2002, \"times_seen\": null}, {\"site\": 873, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -2.9101, \"times_seen\": null}, {\"site\": 873, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -2.995, \"times_seen\": null}, {\"site\": 874, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -2.9952, \"times_seen\": null}, {\"site\": 874, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -1.8158, \"times_seen\": null}, {\"site\": 874, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -1.083, \"times_seen\": null}, {\"site\": 875, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -2.1864, \"times_seen\": null}, {\"site\": 875, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -1.5423, \"times_seen\": null}, {\"site\": 875, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -3.0457, \"times_seen\": null}, {\"site\": 876, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -3.1006, \"times_seen\": null}, {\"site\": 877, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -1.703, \"times_seen\": null}, {\"site\": 877, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -3.1228, \"times_seen\": null}, {\"site\": 878, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 879, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -2.8883, \"times_seen\": null}, {\"site\": 879, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -3.1585, \"times_seen\": null}, {\"site\": 879, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -3.3372, \"times_seen\": null}, {\"site\": 882, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 882, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -2.766, \"times_seen\": null}, {\"site\": 883, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 883, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -0.9736, \"times_seen\": null}, {\"site\": 884, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.0907, \"times_seen\": null}, {\"site\": 885, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -2.771, \"times_seen\": null}, {\"site\": 885, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -3.2601, \"times_seen\": null}, {\"site\": 885, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -1.3239, \"times_seen\": null}, {\"site\": 887, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -3.0009, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.7005, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.6779, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.8072, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -1.7267, \"times_seen\": null}, {\"site\": 890, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -3.0043, \"times_seen\": null}, {\"site\": 890, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -0.3442, \"times_seen\": null}, {\"site\": 891, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.0987, \"times_seen\": null}, {\"site\": 892, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.98, \"times_seen\": null}, {\"site\": 893, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -2.1962, \"times_seen\": null}, {\"site\": 893, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -3.0026, \"times_seen\": null}, {\"site\": 894, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -3.1269, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -2.8593, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -2.4705, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -3.2656, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -1.7283, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -0.2541, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -3.114, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -1.9072, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -2.5266, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -2.9127, \"times_seen\": null}, {\"site\": 898, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 898, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 899, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -3.0013, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.9945, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.4536, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -0.2027, \"times_seen\": null}, {\"site\": 901, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 901, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -2.0755, \"times_seen\": null}, {\"site\": 902, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.8707, \"times_seen\": null}, {\"site\": 902, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.9329, \"times_seen\": null}, {\"site\": 902, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.0613, \"times_seen\": null}, {\"site\": 903, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -3.0814, \"times_seen\": null}, {\"site\": 904, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -0.115, \"times_seen\": null}, {\"site\": 905, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -2.5548, \"times_seen\": null}, {\"site\": 906, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -2.9022, \"times_seen\": null}, {\"site\": 907, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -2.9794, \"times_seen\": null}, {\"site\": 908, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -2.9987, \"times_seen\": null}, {\"site\": 908, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -1.1709, \"times_seen\": null}, {\"site\": 910, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.375, \"times_seen\": null}, {\"site\": 910, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 910, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -3.1312, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -1.9481, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -1.2052, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -3.1761, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -1.4918, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.9571, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.8687, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -2.3525, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -2.9718, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -3.0003, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -1.2773, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.9051, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -3.2613, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 915, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 916, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 916, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.0581, \"times_seen\": null}, {\"site\": 916, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.9814, \"times_seen\": null}, {\"site\": 917, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.9981, \"times_seen\": null}, {\"site\": 917, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 917, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -1.4999, \"times_seen\": null}, {\"site\": 918, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 918, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": -2.9992, \"times_seen\": null}, {\"site\": 919, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 919, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 920, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -3.0157, \"times_seen\": null}, {\"site\": 920, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -1.6968, \"times_seen\": null}, {\"site\": 920, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -3.0143, \"times_seen\": null}, {\"site\": 921, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 922, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 923, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.7711, \"times_seen\": null}, {\"site\": 923, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 924, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -1.6718, \"times_seen\": null}, {\"site\": 924, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -1.4792, \"times_seen\": null}, {\"site\": 925, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 925, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 925, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 926, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -2.9792, \"times_seen\": null}, {\"site\": 927, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 928, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -3.0956, \"times_seen\": null}, {\"site\": 928, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -2.9437, \"times_seen\": null}, {\"site\": 930, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -2.0862, \"times_seen\": null}, {\"site\": 930, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -3.3409, \"times_seen\": null}, {\"site\": 931, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 931, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -2.5924, \"times_seen\": null}, {\"site\": 932, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -2.4683, \"times_seen\": null}, {\"site\": 932, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 933, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.3044, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.6679, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -1.7045, \"times_seen\": null}, {\"site\": 935, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 935, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 935, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 936, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 937, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -1.6109, \"times_seen\": null}, {\"site\": 939, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": -0.4675, \"times_seen\": null}, {\"site\": 941, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -0.1028, \"times_seen\": null}, {\"site\": 944, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.1167, \"times_seen\": null}, {\"site\": 945, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -3.2637, \"times_seen\": null}, {\"site\": 946, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -2.5809, \"times_seen\": null}, {\"site\": 946, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -1.3087, \"times_seen\": null}, {\"site\": 948, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -2.7742, \"times_seen\": null}, {\"site\": 949, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 950, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 950, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.1214, \"times_seen\": null}, {\"site\": 950, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.5388, \"times_seen\": null}, {\"site\": 952, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 952, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 952, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -3.1284, \"times_seen\": null}, {\"site\": 953, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 953, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -2.0292, \"times_seen\": null}, {\"site\": 954, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -2.7546, \"times_seen\": null}, {\"site\": 954, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 954, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -3.0958, \"times_seen\": null}, {\"site\": 955, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 955, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -2.0828, \"times_seen\": null}, {\"site\": 955, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -2.4826, \"times_seen\": null}, {\"site\": 956, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 957, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 957, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 957, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.4506, \"times_seen\": null}, {\"site\": 958, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 958, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -2.8991, \"times_seen\": null}, {\"site\": 959, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.8229, \"times_seen\": null}, {\"site\": 959, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 960, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.911, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.2766, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.712, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": 0.0708, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -2.2766, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -2.6953, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -1.7631, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -2.6644, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -3.0577, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -2.7218, \"times_seen\": null}, {\"site\": 964, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -1.7587, \"times_seen\": null}, {\"site\": 964, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 965, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.1442, \"times_seen\": null}, {\"site\": 966, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 967, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 967, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -2.7936, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.792, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.8535, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -3.0508, \"times_seen\": null}, {\"site\": 969, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 969, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.3768, \"times_seen\": null}, {\"site\": 969, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 970, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 970, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -2.0482, \"times_seen\": null}, {\"site\": 970, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -0.1562, \"times_seen\": null}, {\"site\": 971, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.9942, \"times_seen\": null}, {\"site\": 971, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -1.0597, \"times_seen\": null}, {\"site\": 971, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 972, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 974, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 974, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -3.0155, \"times_seen\": null}, {\"site\": 975, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 975, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.6369, \"times_seen\": null}, {\"site\": 975, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -2.6303, \"times_seen\": null}, {\"site\": 976, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 976, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -1.9653, \"times_seen\": null}, {\"site\": 976, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -3.0261, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -2.7277, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -3.1298, \"times_seen\": null}, {\"site\": 978, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -1.8075, \"times_seen\": null}, {\"site\": 979, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 980, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 980, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.6466, \"times_seen\": null}, {\"site\": 980, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.3742, \"times_seen\": null}, {\"site\": 982, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 982, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -2.4547, \"times_seen\": null}, {\"site\": 984, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 984, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.6678, \"times_seen\": null}, {\"site\": 984, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.3691, \"times_seen\": null}, {\"site\": 985, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.4746, \"times_seen\": null}, {\"site\": 985, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 986, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.5603, \"times_seen\": null}, {\"site\": 986, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.9982, \"times_seen\": null}, {\"site\": 987, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -2.9304, \"times_seen\": null}, {\"site\": 989, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -3.0082, \"times_seen\": null}, {\"site\": 989, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -0.1337, \"times_seen\": null}, {\"site\": 989, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -2.6481, \"times_seen\": null}, {\"site\": 990, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": -0.9604, \"times_seen\": null}, {\"site\": 991, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -3.0081, \"times_seen\": null}, {\"site\": 991, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -3.2113, \"times_seen\": null}, {\"site\": 992, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 992, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -3.0258, \"times_seen\": null}, {\"site\": 992, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.9769, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.9947, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.71, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.9676, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.3938, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -1.7069, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -2.0252, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 996, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 996, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.3833, \"times_seen\": null}, {\"site\": 996, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.312, \"times_seen\": null}, {\"site\": 997, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.983, \"times_seen\": null}, {\"site\": 998, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 999, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -1.1754, \"times_seen\": null}, {\"site\": 999, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 1000, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 1001, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.086, \"times_seen\": null}, {\"site\": 1001, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -3.137, \"times_seen\": null}, {\"site\": 1004, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 1004, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": 1.2037, \"times_seen\": null}, {\"site\": 1004, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": 0.4014, \"times_seen\": null}, {\"site\": 1005, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -3.1121, \"times_seen\": null}, {\"site\": 1006, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -2.8706, \"times_seen\": null}, {\"site\": 1006, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -3.2055, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -2.956, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.9976, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": 0.0937, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -2.674, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -1.6132, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -2.955, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -2.4856, \"times_seen\": null}, {\"site\": 1010, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1011, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1012, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1012, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -0.4353, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -3.0364, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.2801, \"times_seen\": null}, {\"site\": 1014, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.7502, \"times_seen\": null}, {\"site\": 1014, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1015, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1018, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -1.9687, \"times_seen\": null}, {\"site\": 1018, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -1.5061, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -1.672, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.958, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.2784, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -3.0015, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -0.7165, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.5221, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.8854, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1025, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -1.3488, \"times_seen\": null}, {\"site\": 1025, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -1.1122, \"times_seen\": null}, {\"site\": 1026, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1026, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.028, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -3.1432, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -1.0065, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9215, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -3.0479, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9863, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.7992, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9457, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -3.2569, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -3.0016, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9672, \"times_seen\": null}, {\"site\": 1030, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1030, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.6421, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -2.9507, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -0.8952, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.7367, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.744, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -1.6874, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 1034, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1034, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.9471, \"times_seen\": null}, {\"site\": 1035, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1035, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.1395, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.5103, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -3.1583, \"times_seen\": null}, {\"site\": 1037, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1038, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.7063, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.9171, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.3389, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.9823, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -3.0004, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -0.4876, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -3.0044, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1042, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -1.1639, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 1044, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1044, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1044, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -3.3118, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.26, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.0083, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -2.8866, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1046, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1046, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.3805, \"times_seen\": null}, {\"site\": 1047, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -2.7832, \"times_seen\": null}, {\"site\": 1048, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.999, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.7168, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.9766, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.5057, \"times_seen\": null}, {\"site\": 1052, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -3.1635, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -3.265, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1055, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -1.911, \"times_seen\": null}, {\"site\": 1055, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.4864, \"times_seen\": null}, {\"site\": 1057, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -2.9006, \"times_seen\": null}, {\"site\": 1058, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.3743, \"times_seen\": null}, {\"site\": 1059, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -3.053, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.6745, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.4501, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -1.8627, \"times_seen\": null}, {\"site\": 1062, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -0.9906, \"times_seen\": null}, {\"site\": 1062, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -2.9248, \"times_seen\": null}, {\"site\": 1063, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -3.1347, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -1.8727, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -2.9832, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -3.0924, \"times_seen\": null}, {\"site\": 1065, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.9985, \"times_seen\": null}, {\"site\": 1067, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 1067, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -3.0417, \"times_seen\": null}, {\"site\": 1068, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 1068, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -2.9223, \"times_seen\": null}, {\"site\": 1069, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1070, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1071, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1072, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1072, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -2.793, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.5151, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.8967, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -0.9705, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1075, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.8288, \"times_seen\": null}, {\"site\": 1075, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.1007, \"times_seen\": null}, {\"site\": 1076, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -0.3029, \"times_seen\": null}, {\"site\": 1076, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -3.2643, \"times_seen\": null}, {\"site\": 1077, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -0.3397, \"times_seen\": null}, {\"site\": 1077, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1078, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -3.0036, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -3.0716, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -3.0067, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.2886, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1080, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1080, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1081, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.189, \"times_seen\": null}, {\"site\": 1081, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.0339, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -3.0347, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.4516, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -2.078, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.4293, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.5309, \"times_seen\": null}, {\"site\": 1085, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -1.2344, \"times_seen\": null}, {\"site\": 1086, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -3.1209, \"times_seen\": null}, {\"site\": 1086, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -0.1576, \"times_seen\": null}, {\"site\": 1087, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -1.166, \"times_seen\": null}, {\"site\": 1088, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -3.1836, \"times_seen\": null}, {\"site\": 1089, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -2.1064, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -0.8553, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -0.3222, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -2.3225, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -2.9443, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -1.1874, \"times_seen\": null}, {\"site\": 1093, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1094, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1095, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1095, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1096, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -1.4413, \"times_seen\": null}, {\"site\": 1098, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1098, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1099, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 1099, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1100, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1100, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.0507, \"times_seen\": null}, {\"site\": 1101, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -2.867, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -2.6567, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.0867, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.7148, \"times_seen\": null}, {\"site\": 1104, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1105, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -1.8012, \"times_seen\": null}, {\"site\": 1106, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": -2.9219, \"times_seen\": null}, {\"site\": 1107, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -1.6801, \"times_seen\": null}, {\"site\": 1107, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -3.1111, \"times_seen\": null}, {\"site\": 1108, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.946, \"times_seen\": null}, {\"site\": 1110, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -2.7803, \"times_seen\": null}, {\"site\": 1112, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -2.671, \"times_seen\": null}, {\"site\": 1116, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -2.7984, \"times_seen\": null}, {\"site\": 1116, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -3.2216, \"times_seen\": null}, {\"site\": 1118, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -2.5171, \"times_seen\": null}, {\"site\": 1120, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -3.2598, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.9886, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -3.1257, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 1125, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": -2.7083, \"times_seen\": null}, {\"site\": 1126, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.4619, \"times_seen\": null}, {\"site\": 1126, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 1127, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -3.0159, \"times_seen\": null}, {\"site\": 1128, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -2.5563, \"times_seen\": null}, {\"site\": 1128, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 1129, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -0.3274, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.2697, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -2.0997, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 1131, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1132, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1133, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1133, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1133, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.8711, \"times_seen\": null}, {\"site\": 1135, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -2.7638, \"times_seen\": null}, {\"site\": 1135, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -1.1135, \"times_seen\": null}, {\"site\": 1136, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1137, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1138, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1139, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1139, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -1.9059, \"times_seen\": null}, {\"site\": 1140, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1142, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -1.545, \"times_seen\": null}, {\"site\": 1142, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -2.4853, \"times_seen\": null}, {\"site\": 1143, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1143, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.8795, \"times_seen\": null}, {\"site\": 1144, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1145, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1145, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -2.774, \"times_seen\": null}, {\"site\": 1146, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1147, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1148, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": -2.9483, \"times_seen\": null}, {\"site\": 1148, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -2.1789, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 1151, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1152, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -2.0697, \"times_seen\": null}, {\"site\": 1152, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -0.7103, \"times_seen\": null}, {\"site\": 1153, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -2.8933, \"times_seen\": null}, {\"site\": 1154, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -2.8081, \"times_seen\": null}, {\"site\": 1154, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1157, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -2.9246, \"times_seen\": null}, {\"site\": 1158, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -1.62, \"times_seen\": null}, {\"site\": 1158, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.0525, \"times_seen\": null}, {\"site\": 1161, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1163, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.1077, \"times_seen\": null}, {\"site\": 1163, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -3.2137, \"times_seen\": null}, {\"site\": 1166, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -3.1213, \"times_seen\": null}, {\"site\": 1166, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.2359, \"times_seen\": null}, {\"site\": 1167, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.391, \"times_seen\": null}, {\"site\": 1168, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.1459, \"times_seen\": null}, {\"site\": 1168, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -1.695, \"times_seen\": null}, {\"site\": 1169, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1171, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1172, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1172, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -2.0152, \"times_seen\": null}, {\"site\": 1174, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.2962, \"times_seen\": null}, {\"site\": 1175, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1176, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1177, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": -3.1214, \"times_seen\": null}, {\"site\": 1178, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.1879, \"times_seen\": null}, {\"site\": 1179, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -2.8676, \"times_seen\": null}, {\"site\": 1179, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1180, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1180, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -3.2623, \"times_seen\": null}, {\"site\": 1181, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1181, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -2.8217, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -3.1155, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": null, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1183, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -1.4169, \"times_seen\": null}, {\"site\": 1184, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1185, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1186, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1186, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -2.9313, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.126, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -3.2974, \"times_seen\": null}, {\"site\": 1188, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1189, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -1.1747, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -2.8743, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -3.1097, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -1.4736, \"times_seen\": null}, {\"site\": 1191, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1192, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -2.8134, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -0.9579, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -3.2983, \"times_seen\": null}, {\"site\": 1194, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.7933, \"times_seen\": null}, {\"site\": 1195, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -2.2422, \"times_seen\": null}, {\"site\": 1195, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -2.8804, \"times_seen\": null}, {\"site\": 1197, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -2.949, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1199, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1200, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1201, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1202, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1204, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.2522, \"times_seen\": null}, {\"site\": 1205, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -2.8389, \"times_seen\": null}, {\"site\": 1205, \"wildtype\": null, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -0.8033, \"times_seen\": null}, {\"site\": 1206, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -2.9748, \"times_seen\": null}, {\"site\": 1206, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1206, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -0.5447, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -2.6414, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -1.3902, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -2.8901, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": 1.3076, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.9017, \"times_seen\": null}, {\"site\": 1209, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1210, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -0.9333, \"times_seen\": null}, {\"site\": 1210, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.1673, \"times_seen\": null}, {\"site\": 1211, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1212, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -3.1551, \"times_seen\": null}, {\"site\": 1212, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1213, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1213, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.4976, \"times_seen\": null}, {\"site\": 1214, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1214, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -1.5744, \"times_seen\": null}, {\"site\": 1214, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 1215, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1215, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -2.8079, \"times_seen\": null}, {\"site\": 1216, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1217, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1217, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 1218, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1218, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.4574, \"times_seen\": null}, {\"site\": 1219, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -2.9327, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 1221, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1221, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 1222, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1223, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1223, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.4402, \"times_seen\": null}, {\"site\": 1224, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -1.7015, \"times_seen\": null}, {\"site\": 1224, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -1.1773, \"times_seen\": null}, {\"site\": 1227, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -2.0124, \"times_seen\": null}, {\"site\": 1229, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.882, \"times_seen\": null}, {\"site\": 1230, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -1.8772, \"times_seen\": null}, {\"site\": 1231, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.2956, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.0671, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.5153, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": null, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -1.4835, \"times_seen\": null}, {\"site\": 1233, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -1.6538, \"times_seen\": null}, {\"site\": 1235, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -0.5267, \"times_seen\": null}, {\"site\": 1236, \"wildtype\": null, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -2.9838, \"times_seen\": null}, {\"site\": 1238, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.8018, \"times_seen\": null}, {\"site\": 1239, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.2083, \"times_seen\": null}, {\"site\": 1239, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -1.4432, \"times_seen\": null}, {\"site\": 1242, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -1.5664, \"times_seen\": null}, {\"site\": 1242, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -2.3704, \"times_seen\": null}, {\"site\": 1243, \"wildtype\": null, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.3658, \"times_seen\": null}, {\"site\": 1245, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.5006, \"times_seen\": null}, {\"site\": 1246, \"wildtype\": null, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.079, \"times_seen\": null}, {\"site\": 1246, \"wildtype\": null, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.0951, \"times_seen\": null}, {\"site\": 1247, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.4455, \"times_seen\": null}, {\"site\": 1247, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.6552, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": -0.3058, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": null, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.4763, \"times_seen\": null}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_2\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_1\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_2 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.580985050957895,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_4\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_2 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.580985050957895,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-fc41f669a517ef4c8052bd225c7a3cc4\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_3\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_2 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.580985050957895,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_2 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.580985050957895,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 6.9910636155979695, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_2 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.580985050957895,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_1 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_2 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-4.580985050957895,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-fc41f669a517ef4c8052bd225c7a3cc4\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_5\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_2\", \"view_1\", \"view_3\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_1\"]}, {\"name\": \"param_4\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_1\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -4.580985050957895], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_2\", \"view_1\", \"view_3\"]}, {\"name\": \"param_1\", \"bind\": {\"input\": \"range\", \"max\": 1.5161, \"min\": -3.3409, \"name\": \"minimum functional effect\"}, \"value\": -3.3409}, {\"name\": \"param_2\", \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": 1}, {\"name\": \"param_3\", \"bind\": {\"input\": \"range\", \"max\": 6.9910636155979695, \"min\": -4.580985050957895, \"name\": \"minimum max of escape at site\"}, \"value\": -4.580985050957895}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-9631765c1c8eedabe994b76062594ede\": [{\"site\": 1, \"_stat_site_order\": 0}, {\"site\": 2, \"_stat_site_order\": 1}, {\"site\": 3, \"_stat_site_order\": 2}, {\"site\": 4, \"_stat_site_order\": 3}, {\"site\": 5, \"_stat_site_order\": 4}, {\"site\": 6, \"_stat_site_order\": 5}, {\"site\": 7, \"_stat_site_order\": 6}, {\"site\": 8, \"_stat_site_order\": 7}, {\"site\": 9, \"_stat_site_order\": 8}, {\"site\": 10, \"_stat_site_order\": 9}, {\"site\": 11, \"_stat_site_order\": 10}, {\"site\": 12, \"_stat_site_order\": 11}, {\"site\": 13, \"_stat_site_order\": 12}, {\"site\": 14, \"_stat_site_order\": 13}, {\"site\": 15, \"_stat_site_order\": 14}, {\"site\": 16, \"_stat_site_order\": 15}, {\"site\": 17, \"_stat_site_order\": 16}, {\"site\": 18, \"_stat_site_order\": 17}, {\"site\": 19, \"_stat_site_order\": 18}, {\"site\": 20, \"_stat_site_order\": 19}, {\"site\": 21, \"_stat_site_order\": 20}, {\"site\": 22, \"_stat_site_order\": 21}, {\"site\": 23, \"_stat_site_order\": 22}, {\"site\": 24, \"_stat_site_order\": 23}, {\"site\": 25, \"_stat_site_order\": 24}, {\"site\": 26, \"_stat_site_order\": 25}, {\"site\": 27, \"_stat_site_order\": 26}, {\"site\": 28, \"_stat_site_order\": 27}, {\"site\": 29, \"_stat_site_order\": 28}, {\"site\": 30, \"_stat_site_order\": 29}, {\"site\": 31, \"_stat_site_order\": 30}, {\"site\": 32, \"_stat_site_order\": 31}, {\"site\": 33, \"_stat_site_order\": 32}, {\"site\": 34, \"_stat_site_order\": 33}, {\"site\": 35, \"_stat_site_order\": 34}, {\"site\": 36, \"_stat_site_order\": 35}, {\"site\": 37, \"_stat_site_order\": 36}, {\"site\": 38, \"_stat_site_order\": 37}, {\"site\": 39, \"_stat_site_order\": 38}, {\"site\": 40, \"_stat_site_order\": 39}, {\"site\": 41, \"_stat_site_order\": 40}, {\"site\": 42, \"_stat_site_order\": 41}, {\"site\": 43, \"_stat_site_order\": 42}, {\"site\": 44, \"_stat_site_order\": 43}, {\"site\": 45, \"_stat_site_order\": 44}, {\"site\": 46, \"_stat_site_order\": 45}, {\"site\": 47, \"_stat_site_order\": 46}, {\"site\": 48, \"_stat_site_order\": 47}, {\"site\": 49, \"_stat_site_order\": 48}, {\"site\": 50, \"_stat_site_order\": 49}, {\"site\": 51, \"_stat_site_order\": 50}, {\"site\": 52, \"_stat_site_order\": 51}, {\"site\": 53, \"_stat_site_order\": 52}, {\"site\": 54, \"_stat_site_order\": 53}, {\"site\": 55, \"_stat_site_order\": 54}, {\"site\": 56, \"_stat_site_order\": 55}, {\"site\": 57, \"_stat_site_order\": 56}, {\"site\": 58, \"_stat_site_order\": 57}, {\"site\": 59, \"_stat_site_order\": 58}, {\"site\": 60, \"_stat_site_order\": 59}, {\"site\": 61, \"_stat_site_order\": 60}, {\"site\": 62, \"_stat_site_order\": 61}, {\"site\": 63, \"_stat_site_order\": 62}, {\"site\": 64, \"_stat_site_order\": 63}, {\"site\": 65, \"_stat_site_order\": 64}, {\"site\": 66, \"_stat_site_order\": 65}, {\"site\": 67, \"_stat_site_order\": 66}, {\"site\": 68, \"_stat_site_order\": 67}, {\"site\": 69, \"_stat_site_order\": 68}, {\"site\": 70, \"_stat_site_order\": 69}, {\"site\": 71, \"_stat_site_order\": 70}, {\"site\": 72, \"_stat_site_order\": 71}, {\"site\": 73, \"_stat_site_order\": 72}, {\"site\": 74, \"_stat_site_order\": 73}, {\"site\": 75, \"_stat_site_order\": 74}, {\"site\": 76, \"_stat_site_order\": 75}, {\"site\": 77, \"_stat_site_order\": 76}, {\"site\": 78, \"_stat_site_order\": 77}, {\"site\": 79, \"_stat_site_order\": 78}, {\"site\": 80, \"_stat_site_order\": 79}, {\"site\": 81, \"_stat_site_order\": 80}, {\"site\": 82, \"_stat_site_order\": 81}, {\"site\": 83, \"_stat_site_order\": 82}, {\"site\": 84, \"_stat_site_order\": 83}, {\"site\": 85, \"_stat_site_order\": 84}, {\"site\": 86, \"_stat_site_order\": 85}, {\"site\": 87, \"_stat_site_order\": 86}, {\"site\": 88, \"_stat_site_order\": 87}, {\"site\": 89, \"_stat_site_order\": 88}, {\"site\": 90, \"_stat_site_order\": 89}, {\"site\": 91, \"_stat_site_order\": 90}, {\"site\": 92, \"_stat_site_order\": 91}, {\"site\": 93, \"_stat_site_order\": 92}, {\"site\": 94, \"_stat_site_order\": 93}, {\"site\": 95, \"_stat_site_order\": 94}, {\"site\": 96, \"_stat_site_order\": 95}, {\"site\": 97, \"_stat_site_order\": 96}, {\"site\": 98, \"_stat_site_order\": 97}, {\"site\": 99, \"_stat_site_order\": 98}, {\"site\": 100, \"_stat_site_order\": 99}, {\"site\": 101, \"_stat_site_order\": 100}, {\"site\": 102, \"_stat_site_order\": 101}, {\"site\": 103, \"_stat_site_order\": 102}, {\"site\": 104, \"_stat_site_order\": 103}, {\"site\": 105, \"_stat_site_order\": 104}, {\"site\": 106, \"_stat_site_order\": 105}, {\"site\": 107, \"_stat_site_order\": 106}, {\"site\": 108, \"_stat_site_order\": 107}, {\"site\": 109, \"_stat_site_order\": 108}, {\"site\": 110, \"_stat_site_order\": 109}, {\"site\": 111, \"_stat_site_order\": 110}, {\"site\": 112, \"_stat_site_order\": 111}, {\"site\": 113, \"_stat_site_order\": 112}, {\"site\": 114, \"_stat_site_order\": 113}, {\"site\": 115, \"_stat_site_order\": 114}, {\"site\": 116, \"_stat_site_order\": 115}, {\"site\": 117, \"_stat_site_order\": 116}, {\"site\": 118, \"_stat_site_order\": 117}, {\"site\": 119, \"_stat_site_order\": 118}, {\"site\": 120, \"_stat_site_order\": 119}, {\"site\": 121, \"_stat_site_order\": 120}, {\"site\": 122, \"_stat_site_order\": 121}, {\"site\": 123, \"_stat_site_order\": 122}, {\"site\": 124, \"_stat_site_order\": 123}, {\"site\": 125, \"_stat_site_order\": 124}, {\"site\": 126, \"_stat_site_order\": 125}, {\"site\": 127, \"_stat_site_order\": 126}, {\"site\": 128, \"_stat_site_order\": 127}, {\"site\": 129, \"_stat_site_order\": 128}, {\"site\": 130, \"_stat_site_order\": 129}, {\"site\": 131, \"_stat_site_order\": 130}, {\"site\": 132, \"_stat_site_order\": 131}, {\"site\": 133, \"_stat_site_order\": 132}, {\"site\": 134, \"_stat_site_order\": 133}, {\"site\": 135, \"_stat_site_order\": 134}, {\"site\": 136, \"_stat_site_order\": 135}, {\"site\": 137, \"_stat_site_order\": 136}, {\"site\": 138, \"_stat_site_order\": 137}, {\"site\": 139, \"_stat_site_order\": 138}, {\"site\": 140, \"_stat_site_order\": 139}, {\"site\": 141, \"_stat_site_order\": 140}, {\"site\": 142, \"_stat_site_order\": 141}, {\"site\": 143, \"_stat_site_order\": 142}, {\"site\": 144, \"_stat_site_order\": 143}, {\"site\": 145, \"_stat_site_order\": 144}, {\"site\": 146, \"_stat_site_order\": 145}, {\"site\": 147, \"_stat_site_order\": 146}, {\"site\": 148, \"_stat_site_order\": 147}, {\"site\": 149, \"_stat_site_order\": 148}, {\"site\": 150, \"_stat_site_order\": 149}, {\"site\": 151, \"_stat_site_order\": 150}, {\"site\": 152, \"_stat_site_order\": 151}, {\"site\": 153, \"_stat_site_order\": 152}, {\"site\": 154, \"_stat_site_order\": 153}, {\"site\": 155, \"_stat_site_order\": 154}, {\"site\": 156, \"_stat_site_order\": 155}, {\"site\": 157, \"_stat_site_order\": 156}, {\"site\": 158, \"_stat_site_order\": 157}, {\"site\": 159, \"_stat_site_order\": 158}, {\"site\": 160, \"_stat_site_order\": 159}, {\"site\": 161, \"_stat_site_order\": 160}, {\"site\": 162, \"_stat_site_order\": 161}, {\"site\": 163, \"_stat_site_order\": 162}, {\"site\": 164, \"_stat_site_order\": 163}, {\"site\": 165, \"_stat_site_order\": 164}, {\"site\": 166, \"_stat_site_order\": 165}, {\"site\": 167, \"_stat_site_order\": 166}, {\"site\": 168, \"_stat_site_order\": 167}, {\"site\": 169, \"_stat_site_order\": 168}, {\"site\": 170, \"_stat_site_order\": 169}, {\"site\": 171, \"_stat_site_order\": 170}, {\"site\": 172, \"_stat_site_order\": 171}, {\"site\": 173, \"_stat_site_order\": 172}, {\"site\": 174, \"_stat_site_order\": 173}, {\"site\": 175, \"_stat_site_order\": 174}, {\"site\": 176, \"_stat_site_order\": 175}, {\"site\": 177, \"_stat_site_order\": 176}, {\"site\": 178, \"_stat_site_order\": 177}, {\"site\": 179, \"_stat_site_order\": 178}, {\"site\": 180, \"_stat_site_order\": 179}, {\"site\": 181, \"_stat_site_order\": 180}, {\"site\": 182, \"_stat_site_order\": 181}, {\"site\": 183, \"_stat_site_order\": 182}, {\"site\": 184, \"_stat_site_order\": 183}, {\"site\": 185, \"_stat_site_order\": 184}, {\"site\": 186, \"_stat_site_order\": 185}, {\"site\": 187, \"_stat_site_order\": 186}, {\"site\": 188, \"_stat_site_order\": 187}, {\"site\": 189, \"_stat_site_order\": 188}, {\"site\": 190, \"_stat_site_order\": 189}, {\"site\": 191, \"_stat_site_order\": 190}, {\"site\": 192, \"_stat_site_order\": 191}, {\"site\": 193, \"_stat_site_order\": 192}, {\"site\": 194, \"_stat_site_order\": 193}, {\"site\": 195, \"_stat_site_order\": 194}, {\"site\": 196, \"_stat_site_order\": 195}, {\"site\": 197, \"_stat_site_order\": 196}, {\"site\": 198, \"_stat_site_order\": 197}, {\"site\": 199, \"_stat_site_order\": 198}, {\"site\": 200, \"_stat_site_order\": 199}, {\"site\": 201, \"_stat_site_order\": 200}, {\"site\": 202, \"_stat_site_order\": 201}, {\"site\": 203, \"_stat_site_order\": 202}, {\"site\": 204, \"_stat_site_order\": 203}, {\"site\": 205, \"_stat_site_order\": 204}, {\"site\": 206, \"_stat_site_order\": 205}, {\"site\": 207, \"_stat_site_order\": 206}, {\"site\": 208, \"_stat_site_order\": 207}, {\"site\": 209, \"_stat_site_order\": 208}, {\"site\": 210, \"_stat_site_order\": 209}, {\"site\": 211, \"_stat_site_order\": 210}, {\"site\": 212, \"_stat_site_order\": 211}, {\"site\": 213, \"_stat_site_order\": 212}, {\"site\": 214, \"_stat_site_order\": 213}, {\"site\": 215, \"_stat_site_order\": 214}, {\"site\": 216, \"_stat_site_order\": 215}, {\"site\": 217, \"_stat_site_order\": 216}, {\"site\": 218, \"_stat_site_order\": 217}, {\"site\": 219, \"_stat_site_order\": 218}, {\"site\": 220, \"_stat_site_order\": 219}, {\"site\": 221, \"_stat_site_order\": 220}, {\"site\": 222, \"_stat_site_order\": 221}, {\"site\": 223, \"_stat_site_order\": 222}, {\"site\": 224, \"_stat_site_order\": 223}, {\"site\": 225, \"_stat_site_order\": 224}, {\"site\": 226, \"_stat_site_order\": 225}, {\"site\": 227, \"_stat_site_order\": 226}, {\"site\": 228, \"_stat_site_order\": 227}, {\"site\": 229, \"_stat_site_order\": 228}, {\"site\": 230, \"_stat_site_order\": 229}, {\"site\": 231, \"_stat_site_order\": 230}, {\"site\": 232, \"_stat_site_order\": 231}, {\"site\": 233, \"_stat_site_order\": 232}, {\"site\": 234, \"_stat_site_order\": 233}, {\"site\": 235, \"_stat_site_order\": 234}, {\"site\": 236, \"_stat_site_order\": 235}, {\"site\": 237, \"_stat_site_order\": 236}, {\"site\": 238, \"_stat_site_order\": 237}, {\"site\": 239, \"_stat_site_order\": 238}, {\"site\": 240, \"_stat_site_order\": 239}, {\"site\": 241, \"_stat_site_order\": 240}, {\"site\": 242, \"_stat_site_order\": 241}, {\"site\": 243, \"_stat_site_order\": 242}, {\"site\": 244, \"_stat_site_order\": 243}, {\"site\": 245, \"_stat_site_order\": 244}, {\"site\": 246, \"_stat_site_order\": 245}, {\"site\": 247, \"_stat_site_order\": 246}, {\"site\": 248, \"_stat_site_order\": 247}, {\"site\": 249, \"_stat_site_order\": 248}, {\"site\": 250, \"_stat_site_order\": 249}, {\"site\": 251, \"_stat_site_order\": 250}, {\"site\": 252, \"_stat_site_order\": 251}, {\"site\": 253, \"_stat_site_order\": 252}, {\"site\": 254, \"_stat_site_order\": 253}, {\"site\": 255, \"_stat_site_order\": 254}, {\"site\": 256, \"_stat_site_order\": 255}, {\"site\": 257, \"_stat_site_order\": 256}, {\"site\": 258, \"_stat_site_order\": 257}, {\"site\": 259, \"_stat_site_order\": 258}, {\"site\": 260, \"_stat_site_order\": 259}, {\"site\": 261, \"_stat_site_order\": 260}, {\"site\": 262, \"_stat_site_order\": 261}, {\"site\": 263, \"_stat_site_order\": 262}, {\"site\": 264, \"_stat_site_order\": 263}, {\"site\": 265, \"_stat_site_order\": 264}, {\"site\": 266, \"_stat_site_order\": 265}, {\"site\": 267, \"_stat_site_order\": 266}, {\"site\": 268, \"_stat_site_order\": 267}, {\"site\": 269, \"_stat_site_order\": 268}, {\"site\": 270, \"_stat_site_order\": 269}, {\"site\": 271, \"_stat_site_order\": 270}, {\"site\": 272, \"_stat_site_order\": 271}, {\"site\": 273, \"_stat_site_order\": 272}, {\"site\": 274, \"_stat_site_order\": 273}, {\"site\": 275, \"_stat_site_order\": 274}, {\"site\": 276, \"_stat_site_order\": 275}, {\"site\": 277, \"_stat_site_order\": 276}, {\"site\": 278, \"_stat_site_order\": 277}, {\"site\": 279, \"_stat_site_order\": 278}, {\"site\": 280, \"_stat_site_order\": 279}, {\"site\": 281, \"_stat_site_order\": 280}, {\"site\": 282, \"_stat_site_order\": 281}, {\"site\": 283, \"_stat_site_order\": 282}, {\"site\": 284, \"_stat_site_order\": 283}, {\"site\": 285, \"_stat_site_order\": 284}, {\"site\": 286, \"_stat_site_order\": 285}, {\"site\": 287, \"_stat_site_order\": 286}, {\"site\": 288, \"_stat_site_order\": 287}, {\"site\": 289, \"_stat_site_order\": 288}, {\"site\": 290, \"_stat_site_order\": 289}, {\"site\": 291, \"_stat_site_order\": 290}, {\"site\": 292, \"_stat_site_order\": 291}, {\"site\": 293, \"_stat_site_order\": 292}, {\"site\": 294, \"_stat_site_order\": 293}, {\"site\": 295, \"_stat_site_order\": 294}, {\"site\": 296, \"_stat_site_order\": 295}, {\"site\": 297, \"_stat_site_order\": 296}, {\"site\": 298, \"_stat_site_order\": 297}, {\"site\": 299, \"_stat_site_order\": 298}, {\"site\": 300, \"_stat_site_order\": 299}, {\"site\": 301, \"_stat_site_order\": 300}, {\"site\": 302, \"_stat_site_order\": 301}, {\"site\": 303, \"_stat_site_order\": 302}, {\"site\": 304, \"_stat_site_order\": 303}, {\"site\": 305, \"_stat_site_order\": 304}, {\"site\": 306, \"_stat_site_order\": 305}, {\"site\": 307, \"_stat_site_order\": 306}, {\"site\": 308, \"_stat_site_order\": 307}, {\"site\": 309, \"_stat_site_order\": 308}, {\"site\": 310, \"_stat_site_order\": 309}, {\"site\": 311, \"_stat_site_order\": 310}, {\"site\": 312, \"_stat_site_order\": 311}, {\"site\": 313, \"_stat_site_order\": 312}, {\"site\": 314, \"_stat_site_order\": 313}, {\"site\": 315, \"_stat_site_order\": 314}, {\"site\": 316, \"_stat_site_order\": 315}, {\"site\": 317, \"_stat_site_order\": 316}, {\"site\": 318, \"_stat_site_order\": 317}, {\"site\": 319, \"_stat_site_order\": 318}, {\"site\": 320, \"_stat_site_order\": 319}, {\"site\": 321, \"_stat_site_order\": 320}, {\"site\": 322, \"_stat_site_order\": 321}, {\"site\": 323, \"_stat_site_order\": 322}, {\"site\": 324, \"_stat_site_order\": 323}, {\"site\": 325, \"_stat_site_order\": 324}, {\"site\": 326, \"_stat_site_order\": 325}, {\"site\": 327, \"_stat_site_order\": 326}, {\"site\": 328, \"_stat_site_order\": 327}, {\"site\": 329, \"_stat_site_order\": 328}, {\"site\": 330, \"_stat_site_order\": 329}, {\"site\": 331, \"_stat_site_order\": 330}, {\"site\": 332, \"_stat_site_order\": 331}, {\"site\": 333, \"_stat_site_order\": 332}, {\"site\": 334, \"_stat_site_order\": 333}, {\"site\": 335, \"_stat_site_order\": 334}, {\"site\": 336, \"_stat_site_order\": 335}, {\"site\": 337, \"_stat_site_order\": 336}, {\"site\": 338, \"_stat_site_order\": 337}, {\"site\": 339, \"_stat_site_order\": 338}, {\"site\": 340, \"_stat_site_order\": 339}, {\"site\": 341, \"_stat_site_order\": 340}, {\"site\": 342, \"_stat_site_order\": 341}, {\"site\": 343, \"_stat_site_order\": 342}, {\"site\": 345, \"_stat_site_order\": 343}, {\"site\": 346, \"_stat_site_order\": 344}, {\"site\": 347, \"_stat_site_order\": 345}, {\"site\": 348, \"_stat_site_order\": 346}, {\"site\": 349, \"_stat_site_order\": 347}, {\"site\": 350, \"_stat_site_order\": 348}, {\"site\": 351, \"_stat_site_order\": 349}, {\"site\": 352, \"_stat_site_order\": 350}, {\"site\": 353, \"_stat_site_order\": 351}, {\"site\": 354, \"_stat_site_order\": 352}, {\"site\": 355, \"_stat_site_order\": 353}, {\"site\": 356, \"_stat_site_order\": 354}, {\"site\": 357, \"_stat_site_order\": 355}, {\"site\": 358, \"_stat_site_order\": 356}, {\"site\": 359, \"_stat_site_order\": 357}, {\"site\": 360, \"_stat_site_order\": 358}, {\"site\": 361, \"_stat_site_order\": 359}, {\"site\": 362, \"_stat_site_order\": 360}, {\"site\": 363, \"_stat_site_order\": 361}, {\"site\": 364, \"_stat_site_order\": 362}, {\"site\": 365, \"_stat_site_order\": 363}, {\"site\": 366, \"_stat_site_order\": 364}, {\"site\": 367, \"_stat_site_order\": 365}, {\"site\": 368, \"_stat_site_order\": 366}, {\"site\": 369, \"_stat_site_order\": 367}, {\"site\": 370, \"_stat_site_order\": 368}, {\"site\": 371, \"_stat_site_order\": 369}, {\"site\": 372, \"_stat_site_order\": 370}, {\"site\": 373, \"_stat_site_order\": 371}, {\"site\": 374, \"_stat_site_order\": 372}, {\"site\": 375, \"_stat_site_order\": 373}, {\"site\": 376, \"_stat_site_order\": 374}, {\"site\": 377, \"_stat_site_order\": 375}, {\"site\": 378, \"_stat_site_order\": 376}, {\"site\": 379, \"_stat_site_order\": 377}, {\"site\": 380, \"_stat_site_order\": 378}, {\"site\": 381, \"_stat_site_order\": 379}, {\"site\": 382, \"_stat_site_order\": 380}, {\"site\": 383, \"_stat_site_order\": 381}, {\"site\": 384, \"_stat_site_order\": 382}, {\"site\": 385, \"_stat_site_order\": 383}, {\"site\": 386, \"_stat_site_order\": 384}, {\"site\": 387, \"_stat_site_order\": 385}, {\"site\": 388, \"_stat_site_order\": 386}, {\"site\": 389, \"_stat_site_order\": 387}, {\"site\": 390, \"_stat_site_order\": 388}, {\"site\": 391, \"_stat_site_order\": 389}, {\"site\": 392, \"_stat_site_order\": 390}, {\"site\": 393, \"_stat_site_order\": 391}, {\"site\": 394, \"_stat_site_order\": 392}, {\"site\": 395, \"_stat_site_order\": 393}, {\"site\": 396, \"_stat_site_order\": 394}, {\"site\": 397, \"_stat_site_order\": 395}, {\"site\": 398, \"_stat_site_order\": 396}, {\"site\": 399, \"_stat_site_order\": 397}, {\"site\": 400, \"_stat_site_order\": 398}, {\"site\": 401, \"_stat_site_order\": 399}, {\"site\": 402, \"_stat_site_order\": 400}, {\"site\": 403, \"_stat_site_order\": 401}, {\"site\": 404, \"_stat_site_order\": 402}, {\"site\": 405, \"_stat_site_order\": 403}, {\"site\": 406, \"_stat_site_order\": 404}, {\"site\": 407, \"_stat_site_order\": 405}, {\"site\": 408, \"_stat_site_order\": 406}, {\"site\": 409, \"_stat_site_order\": 407}, {\"site\": 410, \"_stat_site_order\": 408}, {\"site\": 411, \"_stat_site_order\": 409}, {\"site\": 412, \"_stat_site_order\": 410}, {\"site\": 413, \"_stat_site_order\": 411}, {\"site\": 414, \"_stat_site_order\": 412}, {\"site\": 415, \"_stat_site_order\": 413}, {\"site\": 416, \"_stat_site_order\": 414}, {\"site\": 417, \"_stat_site_order\": 415}, {\"site\": 418, \"_stat_site_order\": 416}, {\"site\": 419, \"_stat_site_order\": 417}, {\"site\": 420, \"_stat_site_order\": 418}, {\"site\": 421, \"_stat_site_order\": 419}, {\"site\": 422, \"_stat_site_order\": 420}, {\"site\": 423, \"_stat_site_order\": 421}, {\"site\": 424, \"_stat_site_order\": 422}, {\"site\": 425, \"_stat_site_order\": 423}, {\"site\": 426, \"_stat_site_order\": 424}, {\"site\": 427, \"_stat_site_order\": 425}, {\"site\": 428, \"_stat_site_order\": 426}, {\"site\": 429, \"_stat_site_order\": 427}, {\"site\": 430, \"_stat_site_order\": 428}, {\"site\": 431, \"_stat_site_order\": 429}, {\"site\": 432, \"_stat_site_order\": 430}, {\"site\": 433, \"_stat_site_order\": 431}, {\"site\": 434, \"_stat_site_order\": 432}, {\"site\": 435, \"_stat_site_order\": 433}, {\"site\": 436, \"_stat_site_order\": 434}, {\"site\": 437, \"_stat_site_order\": 435}, {\"site\": 438, \"_stat_site_order\": 436}, {\"site\": 439, \"_stat_site_order\": 437}, {\"site\": 440, \"_stat_site_order\": 438}, {\"site\": 441, \"_stat_site_order\": 439}, {\"site\": 442, \"_stat_site_order\": 440}, {\"site\": 443, \"_stat_site_order\": 441}, {\"site\": 444, \"_stat_site_order\": 442}, {\"site\": 445, \"_stat_site_order\": 443}, {\"site\": 446, \"_stat_site_order\": 444}, {\"site\": 447, \"_stat_site_order\": 445}, {\"site\": 448, \"_stat_site_order\": 446}, {\"site\": 449, \"_stat_site_order\": 447}, {\"site\": 450, \"_stat_site_order\": 448}, {\"site\": 451, \"_stat_site_order\": 449}, {\"site\": 452, \"_stat_site_order\": 450}, {\"site\": 453, \"_stat_site_order\": 451}, {\"site\": 454, \"_stat_site_order\": 452}, {\"site\": 455, \"_stat_site_order\": 453}, {\"site\": 456, \"_stat_site_order\": 454}, {\"site\": 457, \"_stat_site_order\": 455}, {\"site\": 458, \"_stat_site_order\": 456}, {\"site\": 459, \"_stat_site_order\": 457}, {\"site\": 460, \"_stat_site_order\": 458}, {\"site\": 461, \"_stat_site_order\": 459}, {\"site\": 462, \"_stat_site_order\": 460}, {\"site\": 463, \"_stat_site_order\": 461}, {\"site\": 464, \"_stat_site_order\": 462}, {\"site\": 465, \"_stat_site_order\": 463}, {\"site\": 466, \"_stat_site_order\": 464}, {\"site\": 467, \"_stat_site_order\": 465}, {\"site\": 468, \"_stat_site_order\": 466}, {\"site\": 469, \"_stat_site_order\": 467}, {\"site\": 470, \"_stat_site_order\": 468}, {\"site\": 471, \"_stat_site_order\": 469}, {\"site\": 472, \"_stat_site_order\": 470}, {\"site\": 473, \"_stat_site_order\": 471}, {\"site\": 474, \"_stat_site_order\": 472}, {\"site\": 475, \"_stat_site_order\": 473}, {\"site\": 476, \"_stat_site_order\": 474}, {\"site\": 477, \"_stat_site_order\": 475}, {\"site\": 478, \"_stat_site_order\": 476}, {\"site\": 479, \"_stat_site_order\": 477}, {\"site\": 480, \"_stat_site_order\": 478}, {\"site\": 481, \"_stat_site_order\": 479}, {\"site\": 482, \"_stat_site_order\": 480}, {\"site\": 483, \"_stat_site_order\": 481}, {\"site\": 484, \"_stat_site_order\": 482}, {\"site\": 485, \"_stat_site_order\": 483}, {\"site\": 486, \"_stat_site_order\": 484}, {\"site\": 487, \"_stat_site_order\": 485}, {\"site\": 488, \"_stat_site_order\": 486}, {\"site\": 489, \"_stat_site_order\": 487}, {\"site\": 490, \"_stat_site_order\": 488}, {\"site\": 491, \"_stat_site_order\": 489}, {\"site\": 492, \"_stat_site_order\": 490}, {\"site\": 493, \"_stat_site_order\": 491}, {\"site\": 494, \"_stat_site_order\": 492}, {\"site\": 495, \"_stat_site_order\": 493}, {\"site\": 496, \"_stat_site_order\": 494}, {\"site\": 497, \"_stat_site_order\": 495}, {\"site\": 498, \"_stat_site_order\": 496}, {\"site\": 499, \"_stat_site_order\": 497}, {\"site\": 500, \"_stat_site_order\": 498}, {\"site\": 501, \"_stat_site_order\": 499}, {\"site\": 502, \"_stat_site_order\": 500}, {\"site\": 503, \"_stat_site_order\": 501}, {\"site\": 504, \"_stat_site_order\": 502}, {\"site\": 505, \"_stat_site_order\": 503}, {\"site\": 506, \"_stat_site_order\": 504}, {\"site\": 507, \"_stat_site_order\": 505}, {\"site\": 508, \"_stat_site_order\": 506}, {\"site\": 509, \"_stat_site_order\": 507}, {\"site\": 510, \"_stat_site_order\": 508}, {\"site\": 511, \"_stat_site_order\": 509}, {\"site\": 512, \"_stat_site_order\": 510}, {\"site\": 513, \"_stat_site_order\": 511}, {\"site\": 514, \"_stat_site_order\": 512}, {\"site\": 515, \"_stat_site_order\": 513}, {\"site\": 516, \"_stat_site_order\": 514}, {\"site\": 517, \"_stat_site_order\": 515}, {\"site\": 518, \"_stat_site_order\": 516}, {\"site\": 519, \"_stat_site_order\": 517}, {\"site\": 520, \"_stat_site_order\": 518}, {\"site\": 521, \"_stat_site_order\": 519}, {\"site\": 522, \"_stat_site_order\": 520}, {\"site\": 523, \"_stat_site_order\": 521}, {\"site\": 524, \"_stat_site_order\": 522}, {\"site\": 525, \"_stat_site_order\": 523}, {\"site\": 526, \"_stat_site_order\": 524}, {\"site\": 527, \"_stat_site_order\": 525}, {\"site\": 528, \"_stat_site_order\": 526}, {\"site\": 529, \"_stat_site_order\": 527}, {\"site\": 530, \"_stat_site_order\": 528}, {\"site\": 531, \"_stat_site_order\": 529}, {\"site\": 532, \"_stat_site_order\": 530}, {\"site\": 533, \"_stat_site_order\": 531}, {\"site\": 534, \"_stat_site_order\": 532}, {\"site\": 535, \"_stat_site_order\": 533}, {\"site\": 536, \"_stat_site_order\": 534}, {\"site\": 537, \"_stat_site_order\": 535}, {\"site\": 538, \"_stat_site_order\": 536}, {\"site\": 539, \"_stat_site_order\": 537}, {\"site\": 540, \"_stat_site_order\": 538}, {\"site\": 541, \"_stat_site_order\": 539}, {\"site\": 542, \"_stat_site_order\": 540}, {\"site\": 543, \"_stat_site_order\": 541}, {\"site\": 544, \"_stat_site_order\": 542}, {\"site\": 545, \"_stat_site_order\": 543}, {\"site\": 546, \"_stat_site_order\": 544}, {\"site\": 547, \"_stat_site_order\": 545}, {\"site\": 548, \"_stat_site_order\": 546}, {\"site\": 549, \"_stat_site_order\": 547}, {\"site\": 550, \"_stat_site_order\": 548}, {\"site\": 551, \"_stat_site_order\": 549}, {\"site\": 552, \"_stat_site_order\": 550}, {\"site\": 553, \"_stat_site_order\": 551}, {\"site\": 554, \"_stat_site_order\": 552}, {\"site\": 555, \"_stat_site_order\": 553}, {\"site\": 556, \"_stat_site_order\": 554}, {\"site\": 557, \"_stat_site_order\": 555}, {\"site\": 558, \"_stat_site_order\": 556}, {\"site\": 559, \"_stat_site_order\": 557}, {\"site\": 560, \"_stat_site_order\": 558}, {\"site\": 561, \"_stat_site_order\": 559}, {\"site\": 562, \"_stat_site_order\": 560}, {\"site\": 563, \"_stat_site_order\": 561}, {\"site\": 564, \"_stat_site_order\": 562}, {\"site\": 565, \"_stat_site_order\": 563}, {\"site\": 566, \"_stat_site_order\": 564}, {\"site\": 567, \"_stat_site_order\": 565}, {\"site\": 568, \"_stat_site_order\": 566}, {\"site\": 569, \"_stat_site_order\": 567}, {\"site\": 570, \"_stat_site_order\": 568}, {\"site\": 571, \"_stat_site_order\": 569}, {\"site\": 572, \"_stat_site_order\": 570}, {\"site\": 573, \"_stat_site_order\": 571}, {\"site\": 574, \"_stat_site_order\": 572}, {\"site\": 575, \"_stat_site_order\": 573}, {\"site\": 576, \"_stat_site_order\": 574}, {\"site\": 577, \"_stat_site_order\": 575}, {\"site\": 578, \"_stat_site_order\": 576}, {\"site\": 579, \"_stat_site_order\": 577}, {\"site\": 580, \"_stat_site_order\": 578}, {\"site\": 581, \"_stat_site_order\": 579}, {\"site\": 582, \"_stat_site_order\": 580}, {\"site\": 583, \"_stat_site_order\": 581}, {\"site\": 584, \"_stat_site_order\": 582}, {\"site\": 585, \"_stat_site_order\": 583}, {\"site\": 586, \"_stat_site_order\": 584}, {\"site\": 587, \"_stat_site_order\": 585}, {\"site\": 588, \"_stat_site_order\": 586}, {\"site\": 589, \"_stat_site_order\": 587}, {\"site\": 590, \"_stat_site_order\": 588}, {\"site\": 591, \"_stat_site_order\": 589}, {\"site\": 592, \"_stat_site_order\": 590}, {\"site\": 593, \"_stat_site_order\": 591}, {\"site\": 594, \"_stat_site_order\": 592}, {\"site\": 595, \"_stat_site_order\": 593}, {\"site\": 596, \"_stat_site_order\": 594}, {\"site\": 597, \"_stat_site_order\": 595}, {\"site\": 598, \"_stat_site_order\": 596}, {\"site\": 599, \"_stat_site_order\": 597}, {\"site\": 600, \"_stat_site_order\": 598}, {\"site\": 601, \"_stat_site_order\": 599}, {\"site\": 602, \"_stat_site_order\": 600}, {\"site\": 603, \"_stat_site_order\": 601}, {\"site\": 604, \"_stat_site_order\": 602}, {\"site\": 605, \"_stat_site_order\": 603}, {\"site\": 606, \"_stat_site_order\": 604}, {\"site\": 607, \"_stat_site_order\": 605}, {\"site\": 608, \"_stat_site_order\": 606}, {\"site\": 609, \"_stat_site_order\": 607}, {\"site\": 610, \"_stat_site_order\": 608}, {\"site\": 611, \"_stat_site_order\": 609}, {\"site\": 612, \"_stat_site_order\": 610}, {\"site\": 613, \"_stat_site_order\": 611}, {\"site\": 614, \"_stat_site_order\": 612}, {\"site\": 615, \"_stat_site_order\": 613}, {\"site\": 616, \"_stat_site_order\": 614}, {\"site\": 617, \"_stat_site_order\": 615}, {\"site\": 618, \"_stat_site_order\": 616}, {\"site\": 619, \"_stat_site_order\": 617}, {\"site\": 620, \"_stat_site_order\": 618}, {\"site\": 621, \"_stat_site_order\": 619}, {\"site\": 622, \"_stat_site_order\": 620}, {\"site\": 623, \"_stat_site_order\": 621}, {\"site\": 624, \"_stat_site_order\": 622}, {\"site\": 625, \"_stat_site_order\": 623}, {\"site\": 626, \"_stat_site_order\": 624}, {\"site\": 627, \"_stat_site_order\": 625}, {\"site\": 628, \"_stat_site_order\": 626}, {\"site\": 629, \"_stat_site_order\": 627}, {\"site\": 630, \"_stat_site_order\": 628}, {\"site\": 631, \"_stat_site_order\": 629}, {\"site\": 632, \"_stat_site_order\": 630}, {\"site\": 633, \"_stat_site_order\": 631}, {\"site\": 634, \"_stat_site_order\": 632}, {\"site\": 635, \"_stat_site_order\": 633}, {\"site\": 636, \"_stat_site_order\": 634}, {\"site\": 637, \"_stat_site_order\": 635}, {\"site\": 638, \"_stat_site_order\": 636}, {\"site\": 639, \"_stat_site_order\": 637}, {\"site\": 640, \"_stat_site_order\": 638}, {\"site\": 641, \"_stat_site_order\": 639}, {\"site\": 642, \"_stat_site_order\": 640}, {\"site\": 643, \"_stat_site_order\": 641}, {\"site\": 644, \"_stat_site_order\": 642}, {\"site\": 645, \"_stat_site_order\": 643}, {\"site\": 646, \"_stat_site_order\": 644}, {\"site\": 647, \"_stat_site_order\": 645}, {\"site\": 648, \"_stat_site_order\": 646}, {\"site\": 649, \"_stat_site_order\": 647}, {\"site\": 650, \"_stat_site_order\": 648}, {\"site\": 651, \"_stat_site_order\": 649}, {\"site\": 652, \"_stat_site_order\": 650}, {\"site\": 653, \"_stat_site_order\": 651}, {\"site\": 654, \"_stat_site_order\": 652}, {\"site\": 655, \"_stat_site_order\": 653}, {\"site\": 656, \"_stat_site_order\": 654}, {\"site\": 657, \"_stat_site_order\": 655}, {\"site\": 658, \"_stat_site_order\": 656}, {\"site\": 659, \"_stat_site_order\": 657}, {\"site\": 660, \"_stat_site_order\": 658}, {\"site\": 661, \"_stat_site_order\": 659}, {\"site\": 662, \"_stat_site_order\": 660}, {\"site\": 663, \"_stat_site_order\": 661}, {\"site\": 664, \"_stat_site_order\": 662}, {\"site\": 665, \"_stat_site_order\": 663}, {\"site\": 666, \"_stat_site_order\": 664}, {\"site\": 667, \"_stat_site_order\": 665}, {\"site\": 668, \"_stat_site_order\": 666}, {\"site\": 669, \"_stat_site_order\": 667}, {\"site\": 670, \"_stat_site_order\": 668}, {\"site\": 671, \"_stat_site_order\": 669}, {\"site\": 672, \"_stat_site_order\": 670}, {\"site\": 673, \"_stat_site_order\": 671}, {\"site\": 674, \"_stat_site_order\": 672}, {\"site\": 675, \"_stat_site_order\": 673}, {\"site\": 676, \"_stat_site_order\": 674}, {\"site\": 677, \"_stat_site_order\": 675}, {\"site\": 678, \"_stat_site_order\": 676}, {\"site\": 679, \"_stat_site_order\": 677}, {\"site\": 680, \"_stat_site_order\": 678}, {\"site\": 681, \"_stat_site_order\": 679}, {\"site\": 682, \"_stat_site_order\": 680}, {\"site\": 683, \"_stat_site_order\": 681}, {\"site\": 684, \"_stat_site_order\": 682}, {\"site\": 685, \"_stat_site_order\": 683}, {\"site\": 686, \"_stat_site_order\": 684}, {\"site\": 687, \"_stat_site_order\": 685}, {\"site\": 688, \"_stat_site_order\": 686}, {\"site\": 689, \"_stat_site_order\": 687}, {\"site\": 690, \"_stat_site_order\": 688}, {\"site\": 691, \"_stat_site_order\": 689}, {\"site\": 693, \"_stat_site_order\": 690}, {\"site\": 694, \"_stat_site_order\": 691}, {\"site\": 695, \"_stat_site_order\": 692}, {\"site\": 696, \"_stat_site_order\": 693}, {\"site\": 697, \"_stat_site_order\": 694}, {\"site\": 698, \"_stat_site_order\": 695}, {\"site\": 699, \"_stat_site_order\": 696}, {\"site\": 700, \"_stat_site_order\": 697}, {\"site\": 701, \"_stat_site_order\": 698}, {\"site\": 702, \"_stat_site_order\": 699}, {\"site\": 703, \"_stat_site_order\": 700}, {\"site\": 704, \"_stat_site_order\": 701}, {\"site\": 705, \"_stat_site_order\": 702}, {\"site\": 706, \"_stat_site_order\": 703}, {\"site\": 707, \"_stat_site_order\": 704}, {\"site\": 708, \"_stat_site_order\": 705}, {\"site\": 709, \"_stat_site_order\": 706}, {\"site\": 710, \"_stat_site_order\": 707}, {\"site\": 711, \"_stat_site_order\": 708}, {\"site\": 712, \"_stat_site_order\": 709}, {\"site\": 713, \"_stat_site_order\": 710}, {\"site\": 714, \"_stat_site_order\": 711}, {\"site\": 715, \"_stat_site_order\": 712}, {\"site\": 716, \"_stat_site_order\": 713}, {\"site\": 717, \"_stat_site_order\": 714}, {\"site\": 718, \"_stat_site_order\": 715}, {\"site\": 719, \"_stat_site_order\": 716}, {\"site\": 720, \"_stat_site_order\": 717}, {\"site\": 721, \"_stat_site_order\": 718}, {\"site\": 722, \"_stat_site_order\": 719}, {\"site\": 723, \"_stat_site_order\": 720}, {\"site\": 724, \"_stat_site_order\": 721}, {\"site\": 725, \"_stat_site_order\": 722}, {\"site\": 726, \"_stat_site_order\": 723}, {\"site\": 727, \"_stat_site_order\": 724}, {\"site\": 728, \"_stat_site_order\": 725}, {\"site\": 729, \"_stat_site_order\": 726}, {\"site\": 730, \"_stat_site_order\": 727}, {\"site\": 731, \"_stat_site_order\": 728}, {\"site\": 732, \"_stat_site_order\": 729}, {\"site\": 733, \"_stat_site_order\": 730}, {\"site\": 734, \"_stat_site_order\": 731}, {\"site\": 735, \"_stat_site_order\": 732}, {\"site\": 736, \"_stat_site_order\": 733}, {\"site\": 737, \"_stat_site_order\": 734}, {\"site\": 738, \"_stat_site_order\": 735}, {\"site\": 739, \"_stat_site_order\": 736}, {\"site\": 740, \"_stat_site_order\": 737}, {\"site\": 741, \"_stat_site_order\": 738}, {\"site\": 742, \"_stat_site_order\": 739}, {\"site\": 743, \"_stat_site_order\": 740}, {\"site\": 744, \"_stat_site_order\": 741}, {\"site\": 745, \"_stat_site_order\": 742}, {\"site\": 746, \"_stat_site_order\": 743}, {\"site\": 747, \"_stat_site_order\": 744}, {\"site\": 748, \"_stat_site_order\": 745}, {\"site\": 749, \"_stat_site_order\": 746}, {\"site\": 750, \"_stat_site_order\": 747}, {\"site\": 751, \"_stat_site_order\": 748}, {\"site\": 752, \"_stat_site_order\": 749}, {\"site\": 753, \"_stat_site_order\": 750}, {\"site\": 754, \"_stat_site_order\": 751}, {\"site\": 755, \"_stat_site_order\": 752}, {\"site\": 756, \"_stat_site_order\": 753}, {\"site\": 757, \"_stat_site_order\": 754}, {\"site\": 758, \"_stat_site_order\": 755}, {\"site\": 759, \"_stat_site_order\": 756}, {\"site\": 760, \"_stat_site_order\": 757}, {\"site\": 761, \"_stat_site_order\": 758}, {\"site\": 762, \"_stat_site_order\": 759}, {\"site\": 763, \"_stat_site_order\": 760}, {\"site\": 764, \"_stat_site_order\": 761}, {\"site\": 765, \"_stat_site_order\": 762}, {\"site\": 766, \"_stat_site_order\": 763}, {\"site\": 767, \"_stat_site_order\": 764}, {\"site\": 768, \"_stat_site_order\": 765}, {\"site\": 769, \"_stat_site_order\": 766}, {\"site\": 770, \"_stat_site_order\": 767}, {\"site\": 771, \"_stat_site_order\": 768}, {\"site\": 772, \"_stat_site_order\": 769}, {\"site\": 773, \"_stat_site_order\": 770}, {\"site\": 774, \"_stat_site_order\": 771}, {\"site\": 775, \"_stat_site_order\": 772}, {\"site\": 776, \"_stat_site_order\": 773}, {\"site\": 777, \"_stat_site_order\": 774}, {\"site\": 778, \"_stat_site_order\": 775}, {\"site\": 779, \"_stat_site_order\": 776}, {\"site\": 780, \"_stat_site_order\": 777}, {\"site\": 781, \"_stat_site_order\": 778}, {\"site\": 782, \"_stat_site_order\": 779}, {\"site\": 783, \"_stat_site_order\": 780}, {\"site\": 784, \"_stat_site_order\": 781}, {\"site\": 785, \"_stat_site_order\": 782}, {\"site\": 786, \"_stat_site_order\": 783}, {\"site\": 787, \"_stat_site_order\": 784}, {\"site\": 788, \"_stat_site_order\": 785}, {\"site\": 789, \"_stat_site_order\": 786}, {\"site\": 790, \"_stat_site_order\": 787}, {\"site\": 791, \"_stat_site_order\": 788}, {\"site\": 792, \"_stat_site_order\": 789}, {\"site\": 793, \"_stat_site_order\": 790}, {\"site\": 794, \"_stat_site_order\": 791}, {\"site\": 795, \"_stat_site_order\": 792}, {\"site\": 796, \"_stat_site_order\": 793}, {\"site\": 797, \"_stat_site_order\": 794}, {\"site\": 798, \"_stat_site_order\": 795}, {\"site\": 799, \"_stat_site_order\": 796}, {\"site\": 800, \"_stat_site_order\": 797}, {\"site\": 801, \"_stat_site_order\": 798}, {\"site\": 802, \"_stat_site_order\": 799}, {\"site\": 803, \"_stat_site_order\": 800}, {\"site\": 804, \"_stat_site_order\": 801}, {\"site\": 805, \"_stat_site_order\": 802}, {\"site\": 806, \"_stat_site_order\": 803}, {\"site\": 807, \"_stat_site_order\": 804}, {\"site\": 808, \"_stat_site_order\": 805}, {\"site\": 809, \"_stat_site_order\": 806}, {\"site\": 810, \"_stat_site_order\": 807}, {\"site\": 811, \"_stat_site_order\": 808}, {\"site\": 812, \"_stat_site_order\": 809}, {\"site\": 813, \"_stat_site_order\": 810}, {\"site\": 814, \"_stat_site_order\": 811}, {\"site\": 815, \"_stat_site_order\": 812}, {\"site\": 816, \"_stat_site_order\": 813}, {\"site\": 817, \"_stat_site_order\": 814}, {\"site\": 818, \"_stat_site_order\": 815}, {\"site\": 819, \"_stat_site_order\": 816}, {\"site\": 820, \"_stat_site_order\": 817}, {\"site\": 821, \"_stat_site_order\": 818}, {\"site\": 822, \"_stat_site_order\": 819}, {\"site\": 823, \"_stat_site_order\": 820}, {\"site\": 824, \"_stat_site_order\": 821}, {\"site\": 825, \"_stat_site_order\": 822}, {\"site\": 826, \"_stat_site_order\": 823}, {\"site\": 827, \"_stat_site_order\": 824}, {\"site\": 828, \"_stat_site_order\": 825}, {\"site\": 829, \"_stat_site_order\": 826}, {\"site\": 830, \"_stat_site_order\": 827}, {\"site\": 831, \"_stat_site_order\": 828}, {\"site\": 832, \"_stat_site_order\": 829}, {\"site\": 833, \"_stat_site_order\": 830}, {\"site\": 834, \"_stat_site_order\": 831}, {\"site\": 835, \"_stat_site_order\": 832}, {\"site\": 836, \"_stat_site_order\": 833}, {\"site\": 837, \"_stat_site_order\": 834}, {\"site\": 838, \"_stat_site_order\": 835}, {\"site\": 839, \"_stat_site_order\": 836}, {\"site\": 840, \"_stat_site_order\": 837}, {\"site\": 841, \"_stat_site_order\": 838}, {\"site\": 842, \"_stat_site_order\": 839}, {\"site\": 843, \"_stat_site_order\": 840}, {\"site\": 844, \"_stat_site_order\": 841}, {\"site\": 845, \"_stat_site_order\": 842}, {\"site\": 846, \"_stat_site_order\": 843}, {\"site\": 847, \"_stat_site_order\": 844}, {\"site\": 848, \"_stat_site_order\": 845}, {\"site\": 849, \"_stat_site_order\": 846}, {\"site\": 850, \"_stat_site_order\": 847}, {\"site\": 851, \"_stat_site_order\": 848}, {\"site\": 852, \"_stat_site_order\": 849}, {\"site\": 853, \"_stat_site_order\": 850}, {\"site\": 854, \"_stat_site_order\": 851}, {\"site\": 855, \"_stat_site_order\": 852}, {\"site\": 856, \"_stat_site_order\": 853}, {\"site\": 857, \"_stat_site_order\": 854}, {\"site\": 858, \"_stat_site_order\": 855}, {\"site\": 859, \"_stat_site_order\": 856}, {\"site\": 860, \"_stat_site_order\": 857}, {\"site\": 861, \"_stat_site_order\": 858}, {\"site\": 862, \"_stat_site_order\": 859}, {\"site\": 863, \"_stat_site_order\": 860}, {\"site\": 864, \"_stat_site_order\": 861}, {\"site\": 865, \"_stat_site_order\": 862}, {\"site\": 866, \"_stat_site_order\": 863}, {\"site\": 867, \"_stat_site_order\": 864}, {\"site\": 868, \"_stat_site_order\": 865}, {\"site\": 869, \"_stat_site_order\": 866}, {\"site\": 870, \"_stat_site_order\": 867}, {\"site\": 871, \"_stat_site_order\": 868}, {\"site\": 872, \"_stat_site_order\": 869}, {\"site\": 873, \"_stat_site_order\": 870}, {\"site\": 874, \"_stat_site_order\": 871}, {\"site\": 875, \"_stat_site_order\": 872}, {\"site\": 876, \"_stat_site_order\": 873}, {\"site\": 877, \"_stat_site_order\": 874}, {\"site\": 878, \"_stat_site_order\": 875}, {\"site\": 879, \"_stat_site_order\": 876}, {\"site\": 880, \"_stat_site_order\": 877}, {\"site\": 881, \"_stat_site_order\": 878}, {\"site\": 882, \"_stat_site_order\": 879}, {\"site\": 883, \"_stat_site_order\": 880}, {\"site\": 884, \"_stat_site_order\": 881}, {\"site\": 885, \"_stat_site_order\": 882}, {\"site\": 886, \"_stat_site_order\": 883}, {\"site\": 887, \"_stat_site_order\": 884}, {\"site\": 888, \"_stat_site_order\": 885}, {\"site\": 889, \"_stat_site_order\": 886}, {\"site\": 890, \"_stat_site_order\": 887}, {\"site\": 891, \"_stat_site_order\": 888}, {\"site\": 892, \"_stat_site_order\": 889}, {\"site\": 893, \"_stat_site_order\": 890}, {\"site\": 894, \"_stat_site_order\": 891}, {\"site\": 895, \"_stat_site_order\": 892}, {\"site\": 896, \"_stat_site_order\": 893}, {\"site\": 897, \"_stat_site_order\": 894}, {\"site\": 898, \"_stat_site_order\": 895}, {\"site\": 899, \"_stat_site_order\": 896}, {\"site\": 900, \"_stat_site_order\": 897}, {\"site\": 901, \"_stat_site_order\": 898}, {\"site\": 902, \"_stat_site_order\": 899}, {\"site\": 903, \"_stat_site_order\": 900}, {\"site\": 904, \"_stat_site_order\": 901}, {\"site\": 905, \"_stat_site_order\": 902}, {\"site\": 906, \"_stat_site_order\": 903}, {\"site\": 907, \"_stat_site_order\": 904}, {\"site\": 908, \"_stat_site_order\": 905}, {\"site\": 909, \"_stat_site_order\": 906}, {\"site\": 910, \"_stat_site_order\": 907}, {\"site\": 911, \"_stat_site_order\": 908}, {\"site\": 912, \"_stat_site_order\": 909}, {\"site\": 913, \"_stat_site_order\": 910}, {\"site\": 914, \"_stat_site_order\": 911}, {\"site\": 915, \"_stat_site_order\": 912}, {\"site\": 916, \"_stat_site_order\": 913}, {\"site\": 917, \"_stat_site_order\": 914}, {\"site\": 918, \"_stat_site_order\": 915}, {\"site\": 919, \"_stat_site_order\": 916}, {\"site\": 920, \"_stat_site_order\": 917}, {\"site\": 921, \"_stat_site_order\": 918}, {\"site\": 922, \"_stat_site_order\": 919}, {\"site\": 923, \"_stat_site_order\": 920}, {\"site\": 924, \"_stat_site_order\": 921}, {\"site\": 925, \"_stat_site_order\": 922}, {\"site\": 926, \"_stat_site_order\": 923}, {\"site\": 927, \"_stat_site_order\": 924}, {\"site\": 928, \"_stat_site_order\": 925}, {\"site\": 929, \"_stat_site_order\": 926}, {\"site\": 930, \"_stat_site_order\": 927}, {\"site\": 931, \"_stat_site_order\": 928}, {\"site\": 932, \"_stat_site_order\": 929}, {\"site\": 933, \"_stat_site_order\": 930}, {\"site\": 934, \"_stat_site_order\": 931}, {\"site\": 935, \"_stat_site_order\": 932}, {\"site\": 936, \"_stat_site_order\": 933}, {\"site\": 937, \"_stat_site_order\": 934}, {\"site\": 938, \"_stat_site_order\": 935}, {\"site\": 939, \"_stat_site_order\": 936}, {\"site\": 940, \"_stat_site_order\": 937}, {\"site\": 941, \"_stat_site_order\": 938}, {\"site\": 942, \"_stat_site_order\": 939}, {\"site\": 943, \"_stat_site_order\": 940}, {\"site\": 944, \"_stat_site_order\": 941}, {\"site\": 945, \"_stat_site_order\": 942}, {\"site\": 946, \"_stat_site_order\": 943}, {\"site\": 947, \"_stat_site_order\": 944}, {\"site\": 948, \"_stat_site_order\": 945}, {\"site\": 949, \"_stat_site_order\": 946}, {\"site\": 950, \"_stat_site_order\": 947}, {\"site\": 951, \"_stat_site_order\": 948}, {\"site\": 952, \"_stat_site_order\": 949}, {\"site\": 953, \"_stat_site_order\": 950}, {\"site\": 954, \"_stat_site_order\": 951}, {\"site\": 955, \"_stat_site_order\": 952}, {\"site\": 956, \"_stat_site_order\": 953}, {\"site\": 957, \"_stat_site_order\": 954}, {\"site\": 958, \"_stat_site_order\": 955}, {\"site\": 959, \"_stat_site_order\": 956}, {\"site\": 960, \"_stat_site_order\": 957}, {\"site\": 961, \"_stat_site_order\": 958}, {\"site\": 962, \"_stat_site_order\": 959}, {\"site\": 963, \"_stat_site_order\": 960}, {\"site\": 964, \"_stat_site_order\": 961}, {\"site\": 965, \"_stat_site_order\": 962}, {\"site\": 966, \"_stat_site_order\": 963}, {\"site\": 967, \"_stat_site_order\": 964}, {\"site\": 968, \"_stat_site_order\": 965}, {\"site\": 969, \"_stat_site_order\": 966}, {\"site\": 970, \"_stat_site_order\": 967}, {\"site\": 971, \"_stat_site_order\": 968}, {\"site\": 972, \"_stat_site_order\": 969}, {\"site\": 973, \"_stat_site_order\": 970}, {\"site\": 974, \"_stat_site_order\": 971}, {\"site\": 975, \"_stat_site_order\": 972}, {\"site\": 976, \"_stat_site_order\": 973}, {\"site\": 977, \"_stat_site_order\": 974}, {\"site\": 978, \"_stat_site_order\": 975}, {\"site\": 979, \"_stat_site_order\": 976}, {\"site\": 980, \"_stat_site_order\": 977}, {\"site\": 981, \"_stat_site_order\": 978}, {\"site\": 982, \"_stat_site_order\": 979}, {\"site\": 983, \"_stat_site_order\": 980}, {\"site\": 984, \"_stat_site_order\": 981}, {\"site\": 985, \"_stat_site_order\": 982}, {\"site\": 986, \"_stat_site_order\": 983}, {\"site\": 987, \"_stat_site_order\": 984}, {\"site\": 988, \"_stat_site_order\": 985}, {\"site\": 989, \"_stat_site_order\": 986}, {\"site\": 990, \"_stat_site_order\": 987}, {\"site\": 991, \"_stat_site_order\": 988}, {\"site\": 992, \"_stat_site_order\": 989}, {\"site\": 993, \"_stat_site_order\": 990}, {\"site\": 994, \"_stat_site_order\": 991}, {\"site\": 995, \"_stat_site_order\": 992}, {\"site\": 996, \"_stat_site_order\": 993}, {\"site\": 997, \"_stat_site_order\": 994}, {\"site\": 998, \"_stat_site_order\": 995}, {\"site\": 999, \"_stat_site_order\": 996}, {\"site\": 1000, \"_stat_site_order\": 997}, {\"site\": 1001, \"_stat_site_order\": 998}, {\"site\": 1002, \"_stat_site_order\": 999}, {\"site\": 1003, \"_stat_site_order\": 1000}, {\"site\": 1004, \"_stat_site_order\": 1001}, {\"site\": 1005, \"_stat_site_order\": 1002}, {\"site\": 1006, \"_stat_site_order\": 1003}, {\"site\": 1007, \"_stat_site_order\": 1004}, {\"site\": 1008, \"_stat_site_order\": 1005}, {\"site\": 1009, \"_stat_site_order\": 1006}, {\"site\": 1010, \"_stat_site_order\": 1007}, {\"site\": 1011, \"_stat_site_order\": 1008}, {\"site\": 1012, \"_stat_site_order\": 1009}, {\"site\": 1013, \"_stat_site_order\": 1010}, {\"site\": 1014, \"_stat_site_order\": 1011}, {\"site\": 1015, \"_stat_site_order\": 1012}, {\"site\": 1016, \"_stat_site_order\": 1013}, {\"site\": 1017, \"_stat_site_order\": 1014}, {\"site\": 1018, \"_stat_site_order\": 1015}, {\"site\": 1019, \"_stat_site_order\": 1016}, {\"site\": 1020, \"_stat_site_order\": 1017}, {\"site\": 1021, \"_stat_site_order\": 1018}, {\"site\": 1022, \"_stat_site_order\": 1019}, {\"site\": 1023, \"_stat_site_order\": 1020}, {\"site\": 1024, \"_stat_site_order\": 1021}, {\"site\": 1025, \"_stat_site_order\": 1022}, {\"site\": 1026, \"_stat_site_order\": 1023}, {\"site\": 1027, \"_stat_site_order\": 1024}, {\"site\": 1028, \"_stat_site_order\": 1025}, {\"site\": 1029, \"_stat_site_order\": 1026}, {\"site\": 1030, \"_stat_site_order\": 1027}, {\"site\": 1031, \"_stat_site_order\": 1028}, {\"site\": 1032, \"_stat_site_order\": 1029}, {\"site\": 1033, \"_stat_site_order\": 1030}, {\"site\": 1034, \"_stat_site_order\": 1031}, {\"site\": 1035, \"_stat_site_order\": 1032}, {\"site\": 1036, \"_stat_site_order\": 1033}, {\"site\": 1037, \"_stat_site_order\": 1034}, {\"site\": 1038, \"_stat_site_order\": 1035}, {\"site\": 1039, \"_stat_site_order\": 1036}, {\"site\": 1040, \"_stat_site_order\": 1037}, {\"site\": 1041, \"_stat_site_order\": 1038}, {\"site\": 1042, \"_stat_site_order\": 1039}, {\"site\": 1043, \"_stat_site_order\": 1040}, {\"site\": 1044, \"_stat_site_order\": 1041}, {\"site\": 1045, \"_stat_site_order\": 1042}, {\"site\": 1046, \"_stat_site_order\": 1043}, {\"site\": 1047, \"_stat_site_order\": 1044}, {\"site\": 1048, \"_stat_site_order\": 1045}, {\"site\": 1049, \"_stat_site_order\": 1046}, {\"site\": 1051, \"_stat_site_order\": 1047}, {\"site\": 1052, \"_stat_site_order\": 1048}, {\"site\": 1053, \"_stat_site_order\": 1049}, {\"site\": 1054, \"_stat_site_order\": 1050}, {\"site\": 1055, \"_stat_site_order\": 1051}, {\"site\": 1056, \"_stat_site_order\": 1052}, {\"site\": 1057, \"_stat_site_order\": 1053}, {\"site\": 1058, \"_stat_site_order\": 1054}, {\"site\": 1059, \"_stat_site_order\": 1055}, {\"site\": 1060, \"_stat_site_order\": 1056}, {\"site\": 1061, \"_stat_site_order\": 1057}, {\"site\": 1062, \"_stat_site_order\": 1058}, {\"site\": 1063, \"_stat_site_order\": 1059}, {\"site\": 1064, \"_stat_site_order\": 1060}, {\"site\": 1065, \"_stat_site_order\": 1061}, {\"site\": 1066, \"_stat_site_order\": 1062}, {\"site\": 1067, \"_stat_site_order\": 1063}, {\"site\": 1068, \"_stat_site_order\": 1064}, {\"site\": 1069, \"_stat_site_order\": 1065}, {\"site\": 1070, \"_stat_site_order\": 1066}, {\"site\": 1071, \"_stat_site_order\": 1067}, {\"site\": 1072, \"_stat_site_order\": 1068}, {\"site\": 1073, \"_stat_site_order\": 1069}, {\"site\": 1074, \"_stat_site_order\": 1070}, {\"site\": 1075, \"_stat_site_order\": 1071}, {\"site\": 1076, \"_stat_site_order\": 1072}, {\"site\": 1077, \"_stat_site_order\": 1073}, {\"site\": 1078, \"_stat_site_order\": 1074}, {\"site\": 1079, \"_stat_site_order\": 1075}, {\"site\": 1080, \"_stat_site_order\": 1076}, {\"site\": 1081, \"_stat_site_order\": 1077}, {\"site\": 1082, \"_stat_site_order\": 1078}, {\"site\": 1083, \"_stat_site_order\": 1079}, {\"site\": 1084, \"_stat_site_order\": 1080}, {\"site\": 1085, \"_stat_site_order\": 1081}, {\"site\": 1086, \"_stat_site_order\": 1082}, {\"site\": 1087, \"_stat_site_order\": 1083}, {\"site\": 1088, \"_stat_site_order\": 1084}, {\"site\": 1089, \"_stat_site_order\": 1085}, {\"site\": 1090, \"_stat_site_order\": 1086}, {\"site\": 1091, \"_stat_site_order\": 1087}, {\"site\": 1092, \"_stat_site_order\": 1088}, {\"site\": 1093, \"_stat_site_order\": 1089}, {\"site\": 1094, \"_stat_site_order\": 1090}, {\"site\": 1095, \"_stat_site_order\": 1091}, {\"site\": 1096, \"_stat_site_order\": 1092}, {\"site\": 1097, \"_stat_site_order\": 1093}, {\"site\": 1098, \"_stat_site_order\": 1094}, {\"site\": 1099, \"_stat_site_order\": 1095}, {\"site\": 1100, \"_stat_site_order\": 1096}, {\"site\": 1101, \"_stat_site_order\": 1097}, {\"site\": 1102, \"_stat_site_order\": 1098}, {\"site\": 1103, \"_stat_site_order\": 1099}, {\"site\": 1104, \"_stat_site_order\": 1100}, {\"site\": 1105, \"_stat_site_order\": 1101}, {\"site\": 1106, \"_stat_site_order\": 1102}, {\"site\": 1107, \"_stat_site_order\": 1103}, {\"site\": 1108, \"_stat_site_order\": 1104}, {\"site\": 1109, \"_stat_site_order\": 1105}, {\"site\": 1110, \"_stat_site_order\": 1106}, {\"site\": 1111, \"_stat_site_order\": 1107}, {\"site\": 1112, \"_stat_site_order\": 1108}, {\"site\": 1113, \"_stat_site_order\": 1109}, {\"site\": 1114, \"_stat_site_order\": 1110}, {\"site\": 1115, \"_stat_site_order\": 1111}, {\"site\": 1116, \"_stat_site_order\": 1112}, {\"site\": 1117, \"_stat_site_order\": 1113}, {\"site\": 1118, \"_stat_site_order\": 1114}, {\"site\": 1119, \"_stat_site_order\": 1115}, {\"site\": 1120, \"_stat_site_order\": 1116}, {\"site\": 1121, \"_stat_site_order\": 1117}, {\"site\": 1122, \"_stat_site_order\": 1118}, {\"site\": 1123, \"_stat_site_order\": 1119}, {\"site\": 1124, \"_stat_site_order\": 1120}, {\"site\": 1125, \"_stat_site_order\": 1121}, {\"site\": 1126, \"_stat_site_order\": 1122}, {\"site\": 1127, \"_stat_site_order\": 1123}, {\"site\": 1128, \"_stat_site_order\": 1124}, {\"site\": 1129, \"_stat_site_order\": 1125}, {\"site\": 1130, \"_stat_site_order\": 1126}, {\"site\": 1131, \"_stat_site_order\": 1127}, {\"site\": 1132, \"_stat_site_order\": 1128}, {\"site\": 1133, \"_stat_site_order\": 1129}, {\"site\": 1134, \"_stat_site_order\": 1130}, {\"site\": 1135, \"_stat_site_order\": 1131}, {\"site\": 1136, \"_stat_site_order\": 1132}, {\"site\": 1137, \"_stat_site_order\": 1133}, {\"site\": 1138, \"_stat_site_order\": 1134}, {\"site\": 1139, \"_stat_site_order\": 1135}, {\"site\": 1140, \"_stat_site_order\": 1136}, {\"site\": 1141, \"_stat_site_order\": 1137}, {\"site\": 1142, \"_stat_site_order\": 1138}, {\"site\": 1143, \"_stat_site_order\": 1139}, {\"site\": 1144, \"_stat_site_order\": 1140}, {\"site\": 1145, \"_stat_site_order\": 1141}, {\"site\": 1146, \"_stat_site_order\": 1142}, {\"site\": 1147, \"_stat_site_order\": 1143}, {\"site\": 1148, \"_stat_site_order\": 1144}, {\"site\": 1149, \"_stat_site_order\": 1145}, {\"site\": 1150, \"_stat_site_order\": 1146}, {\"site\": 1151, \"_stat_site_order\": 1147}, {\"site\": 1152, \"_stat_site_order\": 1148}, {\"site\": 1153, \"_stat_site_order\": 1149}, {\"site\": 1154, \"_stat_site_order\": 1150}, {\"site\": 1155, \"_stat_site_order\": 1151}, {\"site\": 1156, \"_stat_site_order\": 1152}, {\"site\": 1157, \"_stat_site_order\": 1153}, {\"site\": 1158, \"_stat_site_order\": 1154}, {\"site\": 1159, \"_stat_site_order\": 1155}, {\"site\": 1160, \"_stat_site_order\": 1156}, {\"site\": 1161, \"_stat_site_order\": 1157}, {\"site\": 1162, \"_stat_site_order\": 1158}, {\"site\": 1163, \"_stat_site_order\": 1159}, {\"site\": 1164, \"_stat_site_order\": 1160}, {\"site\": 1165, \"_stat_site_order\": 1161}, {\"site\": 1166, \"_stat_site_order\": 1162}, {\"site\": 1167, \"_stat_site_order\": 1163}, {\"site\": 1168, \"_stat_site_order\": 1164}, {\"site\": 1169, \"_stat_site_order\": 1165}, {\"site\": 1170, \"_stat_site_order\": 1166}, {\"site\": 1171, \"_stat_site_order\": 1167}, {\"site\": 1172, \"_stat_site_order\": 1168}, {\"site\": 1173, \"_stat_site_order\": 1169}, {\"site\": 1174, \"_stat_site_order\": 1170}, {\"site\": 1175, \"_stat_site_order\": 1171}, {\"site\": 1176, \"_stat_site_order\": 1172}, {\"site\": 1177, \"_stat_site_order\": 1173}, {\"site\": 1178, \"_stat_site_order\": 1174}, {\"site\": 1179, \"_stat_site_order\": 1175}, {\"site\": 1180, \"_stat_site_order\": 1176}, {\"site\": 1181, \"_stat_site_order\": 1177}, {\"site\": 1182, \"_stat_site_order\": 1178}, {\"site\": 1183, \"_stat_site_order\": 1179}, {\"site\": 1184, \"_stat_site_order\": 1180}, {\"site\": 1185, \"_stat_site_order\": 1181}, {\"site\": 1186, \"_stat_site_order\": 1182}, {\"site\": 1187, \"_stat_site_order\": 1183}, {\"site\": 1188, \"_stat_site_order\": 1184}, {\"site\": 1189, \"_stat_site_order\": 1185}, {\"site\": 1190, \"_stat_site_order\": 1186}, {\"site\": 1191, \"_stat_site_order\": 1187}, {\"site\": 1192, \"_stat_site_order\": 1188}, {\"site\": 1193, \"_stat_site_order\": 1189}, {\"site\": 1194, \"_stat_site_order\": 1190}, {\"site\": 1195, \"_stat_site_order\": 1191}, {\"site\": 1196, \"_stat_site_order\": 1192}, {\"site\": 1197, \"_stat_site_order\": 1193}, {\"site\": 1198, \"_stat_site_order\": 1194}, {\"site\": 1199, \"_stat_site_order\": 1195}, {\"site\": 1200, \"_stat_site_order\": 1196}, {\"site\": 1201, \"_stat_site_order\": 1197}, {\"site\": 1202, \"_stat_site_order\": 1198}, {\"site\": 1203, \"_stat_site_order\": 1199}, {\"site\": 1204, \"_stat_site_order\": 1200}, {\"site\": 1205, \"_stat_site_order\": 1201}, {\"site\": 1206, \"_stat_site_order\": 1202}, {\"site\": 1207, \"_stat_site_order\": 1203}, {\"site\": 1208, \"_stat_site_order\": 1204}, {\"site\": 1209, \"_stat_site_order\": 1205}, {\"site\": 1210, \"_stat_site_order\": 1206}, {\"site\": 1211, \"_stat_site_order\": 1207}, {\"site\": 1212, \"_stat_site_order\": 1208}, {\"site\": 1213, \"_stat_site_order\": 1209}, {\"site\": 1214, \"_stat_site_order\": 1210}, {\"site\": 1215, \"_stat_site_order\": 1211}, {\"site\": 1216, \"_stat_site_order\": 1212}, {\"site\": 1217, \"_stat_site_order\": 1213}, {\"site\": 1218, \"_stat_site_order\": 1214}, {\"site\": 1219, \"_stat_site_order\": 1215}, {\"site\": 1220, \"_stat_site_order\": 1216}, {\"site\": 1221, \"_stat_site_order\": 1217}, {\"site\": 1222, \"_stat_site_order\": 1218}, {\"site\": 1223, \"_stat_site_order\": 1219}, {\"site\": 1224, \"_stat_site_order\": 1220}, {\"site\": 1225, \"_stat_site_order\": 1221}, {\"site\": 1226, \"_stat_site_order\": 1222}, {\"site\": 1227, \"_stat_site_order\": 1223}, {\"site\": 1228, \"_stat_site_order\": 1224}, {\"site\": 1229, \"_stat_site_order\": 1225}, {\"site\": 1230, \"_stat_site_order\": 1226}, {\"site\": 1231, \"_stat_site_order\": 1227}, {\"site\": 1232, \"_stat_site_order\": 1228}, {\"site\": 1233, \"_stat_site_order\": 1229}, {\"site\": 1234, \"_stat_site_order\": 1230}, {\"site\": 1235, \"_stat_site_order\": 1231}, {\"site\": 1236, \"_stat_site_order\": 1232}, {\"site\": 1237, \"_stat_site_order\": 1233}, {\"site\": 1238, \"_stat_site_order\": 1234}, {\"site\": 1239, \"_stat_site_order\": 1235}, {\"site\": 1240, \"_stat_site_order\": 1236}, {\"site\": 1241, \"_stat_site_order\": 1237}, {\"site\": 1242, \"_stat_site_order\": 1238}, {\"site\": 1243, \"_stat_site_order\": 1239}, {\"site\": 1244, \"_stat_site_order\": 1240}, {\"site\": 1245, \"_stat_site_order\": 1241}, {\"site\": 1246, \"_stat_site_order\": 1242}, {\"site\": 1247, \"_stat_site_order\": 1243}, {\"site\": 1248, \"_stat_site_order\": 1244}, {\"site\": 1249, \"_stat_site_order\": 1245}, {\"site\": 1250, \"_stat_site_order\": 1246}], \"data-fc41f669a517ef4c8052bd225c7a3cc4\": [{\"site\": 1, \"mutant\": \"I\", \"escape\": -0.0032009223816103567, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": -2.2303, \"times_seen\": 1.0}, {\"site\": 1, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1, \"mutant\": \"T\", \"escape\": -0.005925119025210988, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": -2.4823, \"times_seen\": 2.0}, {\"site\": 1, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1\", \"functional effect\": -2.3068, \"times_seen\": null}, {\"site\": 2, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 2, \"mutant\": \"I\", \"escape\": -3.112123429145284e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.0498, \"times_seen\": 2.0}, {\"site\": 2, \"mutant\": \"L\", \"escape\": 0.011415116457080226, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.2451, \"times_seen\": 14.0}, {\"site\": 2, \"mutant\": \"S\", \"escape\": -0.009312614667115622, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.382, \"times_seen\": 14.0}, {\"site\": 2, \"mutant\": \"V\", \"escape\": 0.023775891777199402, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": 0.3639, \"times_seen\": 4.0}, {\"site\": 2, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"2\", \"functional effect\": -0.206, \"times_seen\": null}, {\"site\": 3, \"mutant\": \"-\", \"escape\": -0.0020053076439509993, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 3, \"mutant\": \"A\", \"escape\": -0.02787965776756197, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": 0.0936, \"times_seen\": 19.0}, {\"site\": 3, \"mutant\": \"E\", \"escape\": -0.0024054308630661243, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.1408, \"times_seen\": 1.0}, {\"site\": 3, \"mutant\": \"F\", \"escape\": 0.0417867906110877, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.263, \"times_seen\": 91.0}, {\"site\": 3, \"mutant\": \"G\", \"escape\": 0.5648269576886541, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.0572, \"times_seen\": 62.0}, {\"site\": 3, \"mutant\": \"I\", \"escape\": -0.17019865807312196, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.1162, \"times_seen\": 69.0}, {\"site\": 3, \"mutant\": \"L\", \"escape\": -0.010839546499216148, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.052, \"times_seen\": 40.0}, {\"site\": 3, \"mutant\": \"M\", \"escape\": 0.012611978929248467, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": -0.1206, \"times_seen\": 11.0}, {\"site\": 3, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"3\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 4, \"mutant\": \"-\", \"escape\": 0.005095993662764955, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 4, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 4, \"mutant\": \"I\", \"escape\": 0.06442466029861449, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.1365, \"times_seen\": 35.0}, {\"site\": 4, \"mutant\": \"L\", \"escape\": -0.02253128946213819, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": 0.1702, \"times_seen\": 26.0}, {\"site\": 4, \"mutant\": \"S\", \"escape\": 1.0576788363599199, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": -0.4127, \"times_seen\": 28.0}, {\"site\": 4, \"mutant\": \"Y\", \"escape\": -0.02510834254657936, \"epitope\": \"epitope 1\", \"reference_site\": \"4\", \"functional effect\": -0.3325, \"times_seen\": 10.0}, {\"site\": 5, \"mutant\": \"-\", \"escape\": -0.0033404097077828604, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 5, \"mutant\": \"A\", \"escape\": -0.014831025953595636, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.3095, \"times_seen\": 61.0}, {\"site\": 5, \"mutant\": \"C\", \"escape\": -0.09610524567540697, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2806, \"times_seen\": 42.0}, {\"site\": 5, \"mutant\": \"D\", \"escape\": -0.0005876763067128951, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -1.3074, \"times_seen\": 5.0}, {\"site\": 5, \"mutant\": \"E\", \"escape\": 0.0076640196651385365, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -1.5861, \"times_seen\": 7.0}, {\"site\": 5, \"mutant\": \"F\", \"escape\": 0.06832459633474633, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.397, \"times_seen\": 54.0}, {\"site\": 5, \"mutant\": \"G\", \"escape\": -1.024359380820674, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.1809, \"times_seen\": 40.0}, {\"site\": 5, \"mutant\": \"H\", \"escape\": 0.08952946619847776, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2581, \"times_seen\": 53.0}, {\"site\": 5, \"mutant\": \"I\", \"escape\": 0.013882170733263194, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.3636, \"times_seen\": 60.0}, {\"site\": 5, \"mutant\": \"K\", \"escape\": -0.00818050558569654, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -2.9296, \"times_seen\": 1.0}, {\"site\": 5, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 5, \"mutant\": \"M\", \"escape\": -0.2997284210533367, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.2568, \"times_seen\": 44.0}, {\"site\": 5, \"mutant\": \"N\", \"escape\": -0.05153533140179386, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.0041, \"times_seen\": 22.0}, {\"site\": 5, \"mutant\": \"P\", \"escape\": -0.5611956161778558, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -1.1555, \"times_seen\": 115.0}, {\"site\": 5, \"mutant\": \"Q\", \"escape\": 1.0933734483108357, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.6278, \"times_seen\": 2.0}, {\"site\": 5, \"mutant\": \"R\", \"escape\": 0.4973582697960143, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.369, \"times_seen\": 86.0}, {\"site\": 5, \"mutant\": \"S\", \"escape\": 0.2116843822393687, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.0821, \"times_seen\": 97.0}, {\"site\": 5, \"mutant\": \"T\", \"escape\": -0.08583346971588499, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2298, \"times_seen\": 85.0}, {\"site\": 5, \"mutant\": \"V\", \"escape\": 0.03985930061917446, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.2278, \"times_seen\": 57.0}, {\"site\": 5, \"mutant\": \"W\", \"escape\": 0.07890598656774335, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": -0.1663, \"times_seen\": 27.0}, {\"site\": 5, \"mutant\": \"Y\", \"escape\": -0.011843555004198845, \"epitope\": \"epitope 1\", \"reference_site\": \"5\", \"functional effect\": 0.3396, \"times_seen\": 31.0}, {\"site\": 6, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 6, \"mutant\": \"A\", \"escape\": 0.012217775415560817, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.2169, \"times_seen\": 72.0}, {\"site\": 6, \"mutant\": \"C\", \"escape\": -0.010856450957926141, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3016, \"times_seen\": 18.0}, {\"site\": 6, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 6, \"mutant\": \"F\", \"escape\": 0.035026944059295184, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3019, \"times_seen\": 54.0}, {\"site\": 6, \"mutant\": \"I\", \"escape\": 0.008670704413033187, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.374, \"times_seen\": 58.0}, {\"site\": 6, \"mutant\": \"L\", \"escape\": 0.0006021750019252183, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.397, \"times_seen\": 44.0}, {\"site\": 6, \"mutant\": \"M\", \"escape\": -0.0681131694504238, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.3992, \"times_seen\": 16.0}, {\"site\": 6, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 6, \"mutant\": \"W\", \"escape\": -0.0035377708236251, \"epitope\": \"epitope 1\", \"reference_site\": \"6\", \"functional effect\": 0.2707, \"times_seen\": 1.0}, {\"site\": 7, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"F\", \"escape\": -0.0792862482353367, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.187, \"times_seen\": 57.0}, {\"site\": 7, \"mutant\": \"I\", \"escape\": -0.012541348666433713, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.2303, \"times_seen\": 11.0}, {\"site\": 7, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"M\", \"escape\": -0.004402634579992523, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.2428, \"times_seen\": 1.0}, {\"site\": 7, \"mutant\": \"P\", \"escape\": 0.011693412904593262, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -2.1974, \"times_seen\": 3.0}, {\"site\": 7, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -3.1225, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -3.1479, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"7\", \"functional effect\": -0.7825, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"F\", \"escape\": -1.4869022850087703, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -0.7435, \"times_seen\": 31.0}, {\"site\": 8, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"M\", \"escape\": -0.0448967603913258, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": 0.0972, \"times_seen\": 8.0}, {\"site\": 8, \"mutant\": \"P\", \"escape\": -0.02147819558285395, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -2.4719, \"times_seen\": 5.0}, {\"site\": 8, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -2.7606, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"V\", \"escape\": -0.022430037091545018, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -0.6371, \"times_seen\": 10.0}, {\"site\": 8, \"mutant\": \"W\", \"escape\": -0.02750013653526338, \"epitope\": \"epitope 1\", \"reference_site\": \"8\", \"functional effect\": -0.2813, \"times_seen\": 19.0}, {\"site\": 9, \"mutant\": \"-\", \"escape\": -8.809457961419328e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.2833, \"times_seen\": 1.0}, {\"site\": 9, \"mutant\": \"L\", \"escape\": -0.23052583492350753, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.1735, \"times_seen\": 93.0}, {\"site\": 9, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 9, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 9, \"mutant\": \"Q\", \"escape\": 0.09535777222483262, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.1042, \"times_seen\": 17.0}, {\"site\": 9, \"mutant\": \"R\", \"escape\": 0.025411234916806438, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.0833, \"times_seen\": 14.0}, {\"site\": 9, \"mutant\": \"S\", \"escape\": -0.01068679221326321, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.2579, \"times_seen\": 50.0}, {\"site\": 9, \"mutant\": \"T\", \"escape\": 0.3389481887240989, \"epitope\": \"epitope 1\", \"reference_site\": \"9\", \"functional effect\": 0.0953, \"times_seen\": 78.0}, {\"site\": 10, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 10, \"mutant\": \"I\", \"escape\": 0.07169726666198245, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.4444, \"times_seen\": 57.0}, {\"site\": 10, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 10, \"mutant\": \"M\", \"escape\": -0.015302982914930822, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.2022, \"times_seen\": 9.0}, {\"site\": 10, \"mutant\": \"P\", \"escape\": -0.03673355556216727, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": -0.8768, \"times_seen\": 11.0}, {\"site\": 10, \"mutant\": \"Q\", \"escape\": 0.0009445174664117722, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.1603, \"times_seen\": 3.0}, {\"site\": 10, \"mutant\": \"R\", \"escape\": -0.007963138220281808, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": -0.1532, \"times_seen\": 6.0}, {\"site\": 10, \"mutant\": \"V\", \"escape\": -0.039931266694336394, \"epitope\": \"epitope 1\", \"reference_site\": \"10\", \"functional effect\": 0.3729, \"times_seen\": 39.0}, {\"site\": 11, \"mutant\": \"-\", \"escape\": 0.003152652850800128, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": -0.2745, \"times_seen\": 8.0}, {\"site\": 11, \"mutant\": \"A\", \"escape\": -0.001575068722121417, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": -0.1303, \"times_seen\": 5.0}, {\"site\": 11, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": -1.9748, \"times_seen\": null}, {\"site\": 11, \"mutant\": \"F\", \"escape\": -0.03187077560635925, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.3549, \"times_seen\": 45.0}, {\"site\": 11, \"mutant\": \"I\", \"escape\": 0.03405619214850578, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.4444, \"times_seen\": 32.0}, {\"site\": 11, \"mutant\": \"L\", \"escape\": 0.3222505057122933, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.2851, \"times_seen\": 57.0}, {\"site\": 11, \"mutant\": \"M\", \"escape\": 0.044275125162732555, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 11, \"mutant\": \"R\", \"escape\": -0.08293868079871829, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.0913, \"times_seen\": 1.0}, {\"site\": 11, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"11\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -3.2561, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"A\", \"escape\": -0.019095013249006025, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.0764, \"times_seen\": 32.0}, {\"site\": 12, \"mutant\": \"C\", \"escape\": 0.00641001175201743, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2192, \"times_seen\": 47.0}, {\"site\": 12, \"mutant\": \"D\", \"escape\": -0.009346904547286566, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0764, \"times_seen\": 3.0}, {\"site\": 12, \"mutant\": \"E\", \"escape\": -0.018889678497594944, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.1186, \"times_seen\": 6.0}, {\"site\": 12, \"mutant\": \"F\", \"escape\": 0.037935686684986314, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.1239, \"times_seen\": 73.0}, {\"site\": 12, \"mutant\": \"G\", \"escape\": -0.004460546816874213, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.103, \"times_seen\": 8.0}, {\"site\": 12, \"mutant\": \"H\", \"escape\": 0.018122484579228534, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2061, \"times_seen\": 7.0}, {\"site\": 12, \"mutant\": \"I\", \"escape\": 0.017777540181371825, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.1301, \"times_seen\": 9.0}, {\"site\": 12, \"mutant\": \"K\", \"escape\": -0.009474504375853792, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0061, \"times_seen\": 4.0}, {\"site\": 12, \"mutant\": \"L\", \"escape\": 0.2698420468650933, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0117, \"times_seen\": 36.0}, {\"site\": 12, \"mutant\": \"M\", \"escape\": -0.013327599036866457, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.0662, \"times_seen\": 6.0}, {\"site\": 12, \"mutant\": \"N\", \"escape\": 0.0027595369393781876, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2492, \"times_seen\": 12.0}, {\"site\": 12, \"mutant\": \"P\", \"escape\": 0.019443103462310592, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.0798, \"times_seen\": 63.0}, {\"site\": 12, \"mutant\": \"Q\", \"escape\": -0.007355589826488203, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.5121, \"times_seen\": 3.0}, {\"site\": 12, \"mutant\": \"R\", \"escape\": 0.026660437504412337, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2823, \"times_seen\": 22.0}, {\"site\": 12, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"T\", \"escape\": -0.01549622455279426, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0059, \"times_seen\": 44.0}, {\"site\": 12, \"mutant\": \"V\", \"escape\": -0.03744973737759407, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.3056, \"times_seen\": 13.0}, {\"site\": 12, \"mutant\": \"W\", \"escape\": -0.003924596622089544, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": 0.0421, \"times_seen\": 1.0}, {\"site\": 12, \"mutant\": \"Y\", \"escape\": 0.03840672481571418, \"epitope\": \"epitope 1\", \"reference_site\": \"12\", \"functional effect\": -0.2352, \"times_seen\": 47.0}, {\"site\": 13, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 13, \"mutant\": \"-\", \"escape\": -0.002880685863761951, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.0454, \"times_seen\": 1.0}, {\"site\": 13, \"mutant\": \"A\", \"escape\": -0.08328456707577532, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.401, \"times_seen\": 15.0}, {\"site\": 13, \"mutant\": \"C\", \"escape\": 0.026150384278755816, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0129, \"times_seen\": 15.0}, {\"site\": 13, \"mutant\": \"D\", \"escape\": -0.006788152917346171, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 13, \"mutant\": \"E\", \"escape\": 0.0046900131651081214, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.2161, \"times_seen\": 5.0}, {\"site\": 13, \"mutant\": \"F\", \"escape\": -0.012825223171535676, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.1084, \"times_seen\": 6.0}, {\"site\": 13, \"mutant\": \"G\", \"escape\": -0.040288702661126614, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.029, \"times_seen\": 40.0}, {\"site\": 13, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.2003, \"times_seen\": null}, {\"site\": 13, \"mutant\": \"I\", \"escape\": 0.0035898888666373173, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0421, \"times_seen\": 20.0}, {\"site\": 13, \"mutant\": \"K\", \"escape\": -0.020013985764319193, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.1889, \"times_seen\": 3.0}, {\"site\": 13, \"mutant\": \"L\", \"escape\": 0.15285274152544434, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.289, \"times_seen\": 20.0}, {\"site\": 13, \"mutant\": \"M\", \"escape\": -0.019774359552938554, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.1308, \"times_seen\": 7.0}, {\"site\": 13, \"mutant\": \"N\", \"escape\": 0.023776353378437295, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.005, \"times_seen\": 24.0}, {\"site\": 13, \"mutant\": \"P\", \"escape\": -0.0032513327949959476, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.3762, \"times_seen\": 3.0}, {\"site\": 13, \"mutant\": \"Q\", \"escape\": 0.006356476028050185, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.2887, \"times_seen\": 2.0}, {\"site\": 13, \"mutant\": \"R\", \"escape\": 0.009001387290292252, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.5151, \"times_seen\": 16.0}, {\"site\": 13, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 13, \"mutant\": \"T\", \"escape\": -0.011316317782224087, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.2847, \"times_seen\": 6.0}, {\"site\": 13, \"mutant\": \"V\", \"escape\": 0.015567749302714843, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.0634, \"times_seen\": 23.0}, {\"site\": 13, \"mutant\": \"W\", \"escape\": -0.008866608383389865, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": -0.2438, \"times_seen\": 8.0}, {\"site\": 13, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"13\", \"functional effect\": 0.4072, \"times_seen\": null}, {\"site\": 14, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": -2.7736, \"times_seen\": null}, {\"site\": 14, \"mutant\": \"-\", \"escape\": 0.008854414185733852, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.418, \"times_seen\": 11.0}, {\"site\": 14, \"mutant\": \"H\", \"escape\": -0.0644828413038946, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.4201, \"times_seen\": 72.0}, {\"site\": 14, \"mutant\": \"K\", \"escape\": 0.0007767393300306863, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 14, \"mutant\": \"L\", \"escape\": 0.01370430892175945, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.4294, \"times_seen\": 18.0}, {\"site\": 14, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 14, \"mutant\": \"R\", \"escape\": 0.008135187107449142, \"epitope\": \"epitope 1\", \"reference_site\": \"14\", \"functional effect\": -0.1732, \"times_seen\": 45.0}, {\"site\": 15, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": -3.2502, \"times_seen\": null}, {\"site\": 15, \"mutant\": \"-\", \"escape\": 0.00984683946378604, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.0431, \"times_seen\": 23.0}, {\"site\": 15, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 15, \"mutant\": \"F\", \"escape\": -1.1411607459875472, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.2209, \"times_seen\": 73.0}, {\"site\": 15, \"mutant\": \"G\", \"escape\": -0.03554221246301051, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": -0.186, \"times_seen\": 6.0}, {\"site\": 15, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.6185, \"times_seen\": null}, {\"site\": 15, \"mutant\": \"R\", \"escape\": 0.3243949687825544, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.251, \"times_seen\": 11.0}, {\"site\": 15, \"mutant\": \"S\", \"escape\": 0.005140735730016064, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.1163, \"times_seen\": 16.0}, {\"site\": 15, \"mutant\": \"W\", \"escape\": -0.0031280891735296495, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.1541, \"times_seen\": 1.0}, {\"site\": 15, \"mutant\": \"Y\", \"escape\": 0.024528383666238315, \"epitope\": \"epitope 1\", \"reference_site\": \"15\", \"functional effect\": 0.0628, \"times_seen\": 28.0}, {\"site\": 16, \"mutant\": \"-\", \"escape\": -0.08768742419652518, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": -0.136, \"times_seen\": 17.0}, {\"site\": 16, \"mutant\": \"A\", \"escape\": -0.06806454108957695, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": -0.1663, \"times_seen\": 68.0}, {\"site\": 16, \"mutant\": \"F\", \"escape\": -0.09286341984659527, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0322, \"times_seen\": 65.0}, {\"site\": 16, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0858, \"times_seen\": null}, {\"site\": 16, \"mutant\": \"I\", \"escape\": 0.02517027136308138, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0386, \"times_seen\": 49.0}, {\"site\": 16, \"mutant\": \"L\", \"escape\": -0.0190491611357694, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": -0.0772, \"times_seen\": 42.0}, {\"site\": 16, \"mutant\": \"M\", \"escape\": -0.010278932407844324, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.2404, \"times_seen\": 22.0}, {\"site\": 16, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 16, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"16\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 17, \"mutant\": \"-\", \"escape\": -0.0015904021524845919, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": 0.0501, \"times_seen\": 1.0}, {\"site\": 17, \"mutant\": \"D\", \"escape\": 0.21143909854772355, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.376, \"times_seen\": 60.0}, {\"site\": 17, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.8797, \"times_seen\": null}, {\"site\": 17, \"mutant\": \"I\", \"escape\": 0.0053017595993655525, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.5785, \"times_seen\": 11.0}, {\"site\": 17, \"mutant\": \"K\", \"escape\": 0.1659677157909087, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.4162, \"times_seen\": 36.0}, {\"site\": 17, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 17, \"mutant\": \"R\", \"escape\": -6.84187231339091e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.511, \"times_seen\": 9.0}, {\"site\": 17, \"mutant\": \"S\", \"escape\": -0.04164187429986579, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.554, \"times_seen\": 31.0}, {\"site\": 17, \"mutant\": \"Y\", \"escape\": -0.028601139893630813, \"epitope\": \"epitope 1\", \"reference_site\": \"17\", \"functional effect\": -0.5979, \"times_seen\": 19.0}, {\"site\": 18, \"mutant\": \"*\", \"escape\": -0.001378278035736554, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 18, \"mutant\": \"-\", \"escape\": -0.003109776101162976, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0466, \"times_seen\": 1.0}, {\"site\": 18, \"mutant\": \"A\", \"escape\": -0.07919068969459991, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1471, \"times_seen\": 45.0}, {\"site\": 18, \"mutant\": \"C\", \"escape\": 0.0054422735852048725, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.6401, \"times_seen\": 21.0}, {\"site\": 18, \"mutant\": \"D\", \"escape\": -0.00970823187313782, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.2457, \"times_seen\": 13.0}, {\"site\": 18, \"mutant\": \"E\", \"escape\": -0.013810114690683155, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0624, \"times_seen\": 26.0}, {\"site\": 18, \"mutant\": \"F\", \"escape\": 0.2013750185139775, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0948, \"times_seen\": 42.0}, {\"site\": 18, \"mutant\": \"G\", \"escape\": -0.06573527414896312, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.2994, \"times_seen\": 25.0}, {\"site\": 18, \"mutant\": \"H\", \"escape\": 0.005505632969702199, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.2382, \"times_seen\": 24.0}, {\"site\": 18, \"mutant\": \"I\", \"escape\": -0.0007542073603540615, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1222, \"times_seen\": 25.0}, {\"site\": 18, \"mutant\": \"K\", \"escape\": -0.0341456311178849, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.2198, \"times_seen\": 55.0}, {\"site\": 18, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 18, \"mutant\": \"M\", \"escape\": -0.0031032715155600906, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0761, \"times_seen\": 38.0}, {\"site\": 18, \"mutant\": \"N\", \"escape\": -0.010541599049534157, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.3196, \"times_seen\": 9.0}, {\"site\": 18, \"mutant\": \"P\", \"escape\": -0.4283419758115655, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.031, \"times_seen\": 147.0}, {\"site\": 18, \"mutant\": \"Q\", \"escape\": -0.03746248118712153, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1973, \"times_seen\": 51.0}, {\"site\": 18, \"mutant\": \"R\", \"escape\": -0.059161784928665154, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1738, \"times_seen\": 65.0}, {\"site\": 18, \"mutant\": \"S\", \"escape\": -0.44271475640837904, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.0239, \"times_seen\": 50.0}, {\"site\": 18, \"mutant\": \"T\", \"escape\": -0.019192680095434036, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0798, \"times_seen\": 47.0}, {\"site\": 18, \"mutant\": \"V\", \"escape\": 0.12662301756353314, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": 0.017, \"times_seen\": 51.0}, {\"site\": 18, \"mutant\": \"W\", \"escape\": 0.05971306276486464, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.0637, \"times_seen\": 27.0}, {\"site\": 18, \"mutant\": \"Y\", \"escape\": -0.003480961778260683, \"epitope\": \"epitope 1\", \"reference_site\": \"18\", \"functional effect\": -0.1084, \"times_seen\": 14.0}, {\"site\": 19, \"mutant\": \"*\", \"escape\": -0.007349177906462927, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -3.0652, \"times_seen\": 3.0}, {\"site\": 19, \"mutant\": \"-\", \"escape\": -0.001872821359729346, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 19, \"mutant\": \"A\", \"escape\": 0.28697074430857983, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.24, \"times_seen\": 89.0}, {\"site\": 19, \"mutant\": \"C\", \"escape\": -0.030288407750363087, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.6944, \"times_seen\": 24.0}, {\"site\": 19, \"mutant\": \"D\", \"escape\": -0.06507249766361732, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0872, \"times_seen\": 13.0}, {\"site\": 19, \"mutant\": \"E\", \"escape\": 1.401799185725887, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.3967, \"times_seen\": 7.0}, {\"site\": 19, \"mutant\": \"F\", \"escape\": 0.0027054295367708136, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.2889, \"times_seen\": 31.0}, {\"site\": 19, \"mutant\": \"G\", \"escape\": 0.03087881545420938, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.3205, \"times_seen\": 24.0}, {\"site\": 19, \"mutant\": \"H\", \"escape\": -0.0073630931510921885, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.9589, \"times_seen\": 20.0}, {\"site\": 19, \"mutant\": \"I\", \"escape\": -0.003143449860675715, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.2361, \"times_seen\": 81.0}, {\"site\": 19, \"mutant\": \"K\", \"escape\": 0.5727963593608281, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.2149, \"times_seen\": 54.0}, {\"site\": 19, \"mutant\": \"L\", \"escape\": 0.15785687867226653, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.2714, \"times_seen\": 60.0}, {\"site\": 19, \"mutant\": \"M\", \"escape\": 0.001786561813499354, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.03, \"times_seen\": 25.0}, {\"site\": 19, \"mutant\": \"N\", \"escape\": 0.018822457235600526, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.1833, \"times_seen\": 49.0}, {\"site\": 19, \"mutant\": \"P\", \"escape\": -0.012576408380903868, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.0513, \"times_seen\": 105.0}, {\"site\": 19, \"mutant\": \"Q\", \"escape\": -0.06451348326169938, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.5133, \"times_seen\": 17.0}, {\"site\": 19, \"mutant\": \"R\", \"escape\": 0.0031103719948148683, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.0266, \"times_seen\": 91.0}, {\"site\": 19, \"mutant\": \"S\", \"escape\": 0.2834280043429843, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.3007, \"times_seen\": 133.0}, {\"site\": 19, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 19, \"mutant\": \"V\", \"escape\": -0.007947599268220263, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.1003, \"times_seen\": 17.0}, {\"site\": 19, \"mutant\": \"W\", \"escape\": -0.02456315558134684, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": 0.0735, \"times_seen\": 21.0}, {\"site\": 19, \"mutant\": \"Y\", \"escape\": -0.28548380872078527, \"epitope\": \"epitope 1\", \"reference_site\": \"19\", \"functional effect\": -0.0945, \"times_seen\": 25.0}, {\"site\": 20, \"mutant\": \"-\", \"escape\": -0.002803197584404639, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 20, \"mutant\": \"A\", \"escape\": 0.11475518140360312, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.2419, \"times_seen\": 60.0}, {\"site\": 20, \"mutant\": \"I\", \"escape\": -0.12247508181203473, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.2046, \"times_seen\": 77.0}, {\"site\": 20, \"mutant\": \"N\", \"escape\": -0.14088974581024974, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.383, \"times_seen\": 82.0}, {\"site\": 20, \"mutant\": \"P\", \"escape\": -0.02254624022178102, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": -0.0425, \"times_seen\": 28.0}, {\"site\": 20, \"mutant\": \"S\", \"escape\": -0.043592562640294465, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.0782, \"times_seen\": 12.0}, {\"site\": 20, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"20\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 21, \"mutant\": \"-\", \"escape\": -0.00034007513017621097, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 21, \"mutant\": \"E\", \"escape\": -0.028283811431359985, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3483, \"times_seen\": 35.0}, {\"site\": 21, \"mutant\": \"G\", \"escape\": 0.08910619561914276, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3186, \"times_seen\": 138.0}, {\"site\": 21, \"mutant\": \"I\", \"escape\": 0.025532889451302557, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.0568, \"times_seen\": 78.0}, {\"site\": 21, \"mutant\": \"K\", \"escape\": 0.29118188735758144, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3517, \"times_seen\": 97.0}, {\"site\": 21, \"mutant\": \"M\", \"escape\": -0.0020516835893940447, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.157, \"times_seen\": 5.0}, {\"site\": 21, \"mutant\": \"N\", \"escape\": -0.0017851321655949195, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.3257, \"times_seen\": 1.0}, {\"site\": 21, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 21, \"mutant\": \"S\", \"escape\": 0.03247333470498928, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": -0.0945, \"times_seen\": 130.0}, {\"site\": 21, \"mutant\": \"T\", \"escape\": 0.34230063955131207, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.1923, \"times_seen\": 105.0}, {\"site\": 21, \"mutant\": \"W\", \"escape\": -0.0032062384031523185, \"epitope\": \"epitope 1\", \"reference_site\": \"21\", \"functional effect\": 0.2954, \"times_seen\": 3.0}, {\"site\": 22, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.0432, \"times_seen\": null}, {\"site\": 22, \"mutant\": \"A\", \"escape\": 0.14507533607139084, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": -0.2283, \"times_seen\": 109.0}, {\"site\": 22, \"mutant\": \"I\", \"escape\": -0.14026972017830786, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.1231, \"times_seen\": 79.0}, {\"site\": 22, \"mutant\": \"L\", \"escape\": 0.013602058183255846, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.1078, \"times_seen\": 7.0}, {\"site\": 22, \"mutant\": \"N\", \"escape\": -0.07132599377186223, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": -0.1722, \"times_seen\": 83.0}, {\"site\": 22, \"mutant\": \"P\", \"escape\": -0.07179055795516388, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": -0.1872, \"times_seen\": 24.0}, {\"site\": 22, \"mutant\": \"S\", \"escape\": -0.01840270416488763, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.1051, \"times_seen\": 23.0}, {\"site\": 22, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"22\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 23, \"mutant\": \"*\", \"escape\": 0.01464023705061298, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -2.3803, \"times_seen\": 2.0}, {\"site\": 23, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -1.1418, \"times_seen\": null}, {\"site\": 23, \"mutant\": \"E\", \"escape\": 0.02125902631277485, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0926, \"times_seen\": 15.0}, {\"site\": 23, \"mutant\": \"H\", \"escape\": -0.08124266170948129, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0352, \"times_seen\": 141.0}, {\"site\": 23, \"mutant\": \"K\", \"escape\": -0.20917479019995425, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.1144, \"times_seen\": 36.0}, {\"site\": 23, \"mutant\": \"L\", \"escape\": -0.12326602122237412, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0207, \"times_seen\": 62.0}, {\"site\": 23, \"mutant\": \"N\", \"escape\": 0.007659369827957372, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0088, \"times_seen\": 28.0}, {\"site\": 23, \"mutant\": \"P\", \"escape\": -0.07610881058058314, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -0.2311, \"times_seen\": 30.0}, {\"site\": 23, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 23, \"mutant\": \"R\", \"escape\": -0.03641906559800156, \"epitope\": \"epitope 1\", \"reference_site\": \"23\", \"functional effect\": -0.0953, \"times_seen\": 60.0}, {\"site\": 24, \"mutant\": \"-\", \"escape\": -0.8548144608536433, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.0184, \"times_seen\": 59.0}, {\"site\": 24, \"mutant\": \"F\", \"escape\": -0.11845765290647303, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.2565, \"times_seen\": 36.0}, {\"site\": 24, \"mutant\": \"H\", \"escape\": -0.00537451897519493, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.2929, \"times_seen\": 1.0}, {\"site\": 24, \"mutant\": \"I\", \"escape\": 0.0101076737126429, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.4616, \"times_seen\": 23.0}, {\"site\": 24, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 24, \"mutant\": \"P\", \"escape\": 0.0007793442475998589, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.0642, \"times_seen\": 2.0}, {\"site\": 24, \"mutant\": \"Q\", \"escape\": -0.006614040784324453, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 24, \"mutant\": \"R\", \"escape\": 0.004622249378343409, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.0902, \"times_seen\": 1.0}, {\"site\": 24, \"mutant\": \"S\", \"escape\": -0.040046351822490375, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.1515, \"times_seen\": 23.0}, {\"site\": 24, \"mutant\": \"V\", \"escape\": 0.0005877951444386345, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": 0.1116, \"times_seen\": 3.0}, {\"site\": 24, \"mutant\": \"Y\", \"escape\": -0.05391191387327277, \"epitope\": \"epitope 1\", \"reference_site\": \"24\", \"functional effect\": -0.1582, \"times_seen\": 14.0}, {\"site\": 25, \"mutant\": \"-\", \"escape\": -0.15217155106155567, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.0124, \"times_seen\": 91.0}, {\"site\": 25, \"mutant\": \"A\", \"escape\": 0.010898825537348686, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"mutant\": \"H\", \"escape\": -0.15683648047213114, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.0359, \"times_seen\": 106.0}, {\"site\": 25, \"mutant\": \"L\", \"escape\": -0.42898384994052785, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.0811, \"times_seen\": 119.0}, {\"site\": 25, \"mutant\": \"M\", \"escape\": 0.002276582622542246, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 25, \"mutant\": \"S\", \"escape\": 0.009203337511826252, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.1673, \"times_seen\": 73.0}, {\"site\": 25, \"mutant\": \"T\", \"escape\": -0.630845182536314, \"epitope\": \"epitope 1\", \"reference_site\": \"25\", \"functional effect\": -0.2096, \"times_seen\": 102.0}, {\"site\": 26, \"mutant\": \"*\", \"escape\": -0.04519528988215218, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -2.9872, \"times_seen\": 8.0}, {\"site\": 26, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 26, \"mutant\": \"A\", \"escape\": -0.2121017313619674, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0665, \"times_seen\": 177.0}, {\"site\": 26, \"mutant\": \"C\", \"escape\": -0.19726498925818717, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.25, \"times_seen\": 43.0}, {\"site\": 26, \"mutant\": \"D\", \"escape\": -0.8068532325415949, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0853, \"times_seen\": 38.0}, {\"site\": 26, \"mutant\": \"E\", \"escape\": -0.027608053316910654, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.1077, \"times_seen\": 73.0}, {\"site\": 26, \"mutant\": \"F\", \"escape\": -0.313065610371811, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.1031, \"times_seen\": 73.0}, {\"site\": 26, \"mutant\": \"G\", \"escape\": -0.010960864422475687, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.2147, \"times_seen\": 110.0}, {\"site\": 26, \"mutant\": \"H\", \"escape\": 0.0014200743894176458, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.082, \"times_seen\": 157.0}, {\"site\": 26, \"mutant\": \"I\", \"escape\": -0.016343465759298226, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0365, \"times_seen\": 47.0}, {\"site\": 26, \"mutant\": \"K\", \"escape\": -0.10739416097702223, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.11, \"times_seen\": 62.0}, {\"site\": 26, \"mutant\": \"L\", \"escape\": -0.0425009779115628, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0377, \"times_seen\": 300.0}, {\"site\": 26, \"mutant\": \"M\", \"escape\": -0.6716928928850792, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0335, \"times_seen\": 74.0}, {\"site\": 26, \"mutant\": \"N\", \"escape\": -0.09076700351004886, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.2281, \"times_seen\": 43.0}, {\"site\": 26, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 26, \"mutant\": \"Q\", \"escape\": 0.22717760162050937, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.125, \"times_seen\": 96.0}, {\"site\": 26, \"mutant\": \"R\", \"escape\": -0.1352390913310498, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0945, \"times_seen\": 207.0}, {\"site\": 26, \"mutant\": \"S\", \"escape\": -0.04289052710998338, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0988, \"times_seen\": 185.0}, {\"site\": 26, \"mutant\": \"T\", \"escape\": 0.06573601585276583, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.0287, \"times_seen\": 161.0}, {\"site\": 26, \"mutant\": \"V\", \"escape\": 0.015610868758268745, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.0265, \"times_seen\": 122.0}, {\"site\": 26, \"mutant\": \"W\", \"escape\": 0.02270142191199837, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": -0.2387, \"times_seen\": 26.0}, {\"site\": 26, \"mutant\": \"Y\", \"escape\": -0.11379673483283391, \"epitope\": \"epitope 1\", \"reference_site\": \"26\", \"functional effect\": 0.033, \"times_seen\": 53.0}, {\"site\": 27, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 27, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 27, \"mutant\": \"D\", \"escape\": 0.1799866560465935, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.1383, \"times_seen\": 5.0}, {\"site\": 27, \"mutant\": \"E\", \"escape\": -0.06135816808274263, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.081, \"times_seen\": 11.0}, {\"site\": 27, \"mutant\": \"G\", \"escape\": 0.016391354841274783, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": 0.0321, \"times_seen\": 27.0}, {\"site\": 27, \"mutant\": \"L\", \"escape\": 0.004458559816154001, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.2663, \"times_seen\": 13.0}, {\"site\": 27, \"mutant\": \"P\", \"escape\": -0.0357528921170256, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.7404, \"times_seen\": 29.0}, {\"site\": 27, \"mutant\": \"S\", \"escape\": 0.0735361116255673, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.2984, \"times_seen\": 57.0}, {\"site\": 27, \"mutant\": \"T\", \"escape\": -0.009400102600038656, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.1758, \"times_seen\": 107.0}, {\"site\": 27, \"mutant\": \"V\", \"escape\": -0.016338684278957884, \"epitope\": \"epitope 1\", \"reference_site\": \"27\", \"functional effect\": -0.2406, \"times_seen\": 70.0}, {\"site\": 28, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -2.7365, \"times_seen\": null}, {\"site\": 28, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 28, \"mutant\": \"C\", \"escape\": -0.125030556969272, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.1402, \"times_seen\": 34.0}, {\"site\": 28, \"mutant\": \"D\", \"escape\": 0.014440926194599055, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.1212, \"times_seen\": 26.0}, {\"site\": 28, \"mutant\": \"F\", \"escape\": 0.012580812643253447, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.0107, \"times_seen\": 25.0}, {\"site\": 28, \"mutant\": \"H\", \"escape\": 0.25824581667904506, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.2076, \"times_seen\": 147.0}, {\"site\": 28, \"mutant\": \"L\", \"escape\": -0.002641940861775479, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.3199, \"times_seen\": 1.0}, {\"site\": 28, \"mutant\": \"N\", \"escape\": 0.056980374873798104, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": -0.034, \"times_seen\": 30.0}, {\"site\": 28, \"mutant\": \"S\", \"escape\": -0.0017298353108319475, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.2182, \"times_seen\": 1.0}, {\"site\": 28, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 28, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"28\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 29, \"mutant\": \"*\", \"escape\": 0.01853611107874501, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -2.7073, \"times_seen\": 1.0}, {\"site\": 29, \"mutant\": \"A\", \"escape\": 0.022074668306296938, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0217, \"times_seen\": 135.0}, {\"site\": 29, \"mutant\": \"C\", \"escape\": -0.0015918367094882745, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": 0.0151, \"times_seen\": 37.0}, {\"site\": 29, \"mutant\": \"D\", \"escape\": 0.0697702196864616, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.9919, \"times_seen\": 35.0}, {\"site\": 29, \"mutant\": \"E\", \"escape\": 0.03941642487232345, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.6248, \"times_seen\": 22.0}, {\"site\": 29, \"mutant\": \"F\", \"escape\": 0.15987553614946573, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.3225, \"times_seen\": 60.0}, {\"site\": 29, \"mutant\": \"G\", \"escape\": 0.006996678490179402, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2236, \"times_seen\": 19.0}, {\"site\": 29, \"mutant\": \"H\", \"escape\": -0.13589205723917025, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2165, \"times_seen\": 76.0}, {\"site\": 29, \"mutant\": \"I\", \"escape\": -0.13021947022951158, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.1728, \"times_seen\": 144.0}, {\"site\": 29, \"mutant\": \"K\", \"escape\": 0.02949361677624573, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0741, \"times_seen\": 29.0}, {\"site\": 29, \"mutant\": \"L\", \"escape\": -0.13373036502652283, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2727, \"times_seen\": 120.0}, {\"site\": 29, \"mutant\": \"M\", \"escape\": 0.06030642716289278, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0634, \"times_seen\": 31.0}, {\"site\": 29, \"mutant\": \"N\", \"escape\": 0.030399178276080845, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -1.1027, \"times_seen\": 54.0}, {\"site\": 29, \"mutant\": \"P\", \"escape\": -0.14729281935995622, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.7726, \"times_seen\": 117.0}, {\"site\": 29, \"mutant\": \"Q\", \"escape\": -0.03998130149511882, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2614, \"times_seen\": 22.0}, {\"site\": 29, \"mutant\": \"R\", \"escape\": 0.09033529588898011, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.0754, \"times_seen\": 56.0}, {\"site\": 29, \"mutant\": \"S\", \"escape\": -0.002086300554541569, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.1188, \"times_seen\": 187.0}, {\"site\": 29, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 29, \"mutant\": \"V\", \"escape\": 0.0415161365470341, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.1554, \"times_seen\": 63.0}, {\"site\": 29, \"mutant\": \"W\", \"escape\": -0.059595362346097386, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.3719, \"times_seen\": 28.0}, {\"site\": 29, \"mutant\": \"Y\", \"escape\": -1.489315901334954, \"epitope\": \"epitope 1\", \"reference_site\": \"29\", \"functional effect\": -0.2473, \"times_seen\": 56.0}, {\"site\": 30, \"mutant\": \"D\", \"escape\": -0.0918234376879026, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.2915, \"times_seen\": 19.0}, {\"site\": 30, \"mutant\": \"G\", \"escape\": -0.003900211901295494, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -1.4364, \"times_seen\": 1.0}, {\"site\": 30, \"mutant\": \"H\", \"escape\": 0.01460598811438213, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.1785, \"times_seen\": 95.0}, {\"site\": 30, \"mutant\": \"I\", \"escape\": -0.016996686917546563, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.0096, \"times_seen\": 25.0}, {\"site\": 30, \"mutant\": \"K\", \"escape\": -0.00873558699800478, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.1346, \"times_seen\": 72.0}, {\"site\": 30, \"mutant\": \"L\", \"escape\": 0.007275741295548185, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.1372, \"times_seen\": 13.0}, {\"site\": 30, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 30, \"mutant\": \"S\", \"escape\": 0.11291859731021756, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.1031, \"times_seen\": 93.0}, {\"site\": 30, \"mutant\": \"T\", \"escape\": -0.02745158109223316, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": 0.0444, \"times_seen\": 42.0}, {\"site\": 30, \"mutant\": \"Y\", \"escape\": -0.08843066147333131, \"epitope\": \"epitope 1\", \"reference_site\": \"30\", \"functional effect\": -0.1011, \"times_seen\": 33.0}, {\"site\": 31, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": 0.1285, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"F\", \"escape\": -0.046757989921353965, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -1.6643, \"times_seen\": 14.0}, {\"site\": 31, \"mutant\": \"I\", \"escape\": 0.12863545799121517, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -0.6806, \"times_seen\": 12.0}, {\"site\": 31, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -3.1061, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"P\", \"escape\": 0.01905067997337298, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -2.6768, \"times_seen\": 1.0}, {\"site\": 31, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"T\", \"escape\": -0.009177476489570171, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -0.5595, \"times_seen\": 3.0}, {\"site\": 31, \"mutant\": \"Y\", \"escape\": 0.014530576150646873, \"epitope\": \"epitope 1\", \"reference_site\": \"31\", \"functional effect\": -2.2492, \"times_seen\": 3.0}, {\"site\": 32, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 32, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -2.098, \"times_seen\": null}, {\"site\": 32, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 32, \"mutant\": \"I\", \"escape\": -0.01901629538700636, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.3272, \"times_seen\": 4.0}, {\"site\": 32, \"mutant\": \"L\", \"escape\": 0.0806327257217846, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 32, \"mutant\": \"S\", \"escape\": -0.8869140035138146, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.2503, \"times_seen\": 32.0}, {\"site\": 32, \"mutant\": \"V\", \"escape\": -0.007872584554592055, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": 0.2702, \"times_seen\": 7.0}, {\"site\": 32, \"mutant\": \"Y\", \"escape\": -0.43325416932755545, \"epitope\": \"epitope 1\", \"reference_site\": \"32\", \"functional effect\": -0.0009, \"times_seen\": 27.0}, {\"site\": 33, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 33, \"mutant\": \"A\", \"escape\": -0.08560116352605099, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.5022, \"times_seen\": 11.0}, {\"site\": 33, \"mutant\": \"I\", \"escape\": 0.046527383479372776, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.3319, \"times_seen\": 74.0}, {\"site\": 33, \"mutant\": \"K\", \"escape\": 0.09475766048065035, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.0638, \"times_seen\": 14.0}, {\"site\": 33, \"mutant\": \"N\", \"escape\": -0.0149886411218277, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.0747, \"times_seen\": 4.0}, {\"site\": 33, \"mutant\": \"R\", \"escape\": -0.2737608713172868, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.1335, \"times_seen\": 6.0}, {\"site\": 33, \"mutant\": \"S\", \"escape\": -0.013309409156783986, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": -0.1264, \"times_seen\": 16.0}, {\"site\": 33, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"33\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 34, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 34, \"mutant\": \"C\", \"escape\": -0.005425183243615077, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.913, \"times_seen\": 3.0}, {\"site\": 34, \"mutant\": \"G\", \"escape\": -0.04069961218880302, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -2.8329, \"times_seen\": 2.0}, {\"site\": 34, \"mutant\": \"H\", \"escape\": 0.011087694937852232, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": 0.0507, \"times_seen\": 7.0}, {\"site\": 34, \"mutant\": \"K\", \"escape\": -0.011055239152371105, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -0.6047, \"times_seen\": 13.0}, {\"site\": 34, \"mutant\": \"L\", \"escape\": -0.004623142454191724, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.2083, \"times_seen\": 15.0}, {\"site\": 34, \"mutant\": \"M\", \"escape\": -0.008004637938549393, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -2.7512, \"times_seen\": 3.0}, {\"site\": 34, \"mutant\": \"P\", \"escape\": -0.003746573426123175, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -2.963, \"times_seen\": 1.0}, {\"site\": 34, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 34, \"mutant\": \"S\", \"escape\": -0.0018417100315488268, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.472, \"times_seen\": 1.0}, {\"site\": 34, \"mutant\": \"T\", \"escape\": -0.02338601983842501, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -1.6049, \"times_seen\": 3.0}, {\"site\": 34, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"34\", \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.7648, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"C\", \"escape\": -0.2775906776118366, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.7398, \"times_seen\": 31.0}, {\"site\": 35, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -1.9509, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"R\", \"escape\": 0.008757188794018772, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -2.2796, \"times_seen\": 7.0}, {\"site\": 35, \"mutant\": \"S\", \"escape\": -0.03972845362977948, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.2414, \"times_seen\": 15.0}, {\"site\": 35, \"mutant\": \"V\", \"escape\": 0.03016660678379321, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -0.5298, \"times_seen\": 21.0}, {\"site\": 35, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"35\", \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 36, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 36, \"mutant\": \"A\", \"escape\": 0.0059551758541018665, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.2626, \"times_seen\": 14.0}, {\"site\": 36, \"mutant\": \"C\", \"escape\": -0.0014252908940787727, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.2184, \"times_seen\": 7.0}, {\"site\": 36, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -1.2668, \"times_seen\": null}, {\"site\": 36, \"mutant\": \"F\", \"escape\": -0.10202321034658939, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.3847, \"times_seen\": 33.0}, {\"site\": 36, \"mutant\": \"I\", \"escape\": 0.16432408075290084, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": 0.2168, \"times_seen\": 79.0}, {\"site\": 36, \"mutant\": \"L\", \"escape\": -0.013175033539808569, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": 0.1621, \"times_seen\": 4.0}, {\"site\": 36, \"mutant\": \"T\", \"escape\": -0.0039148903177117795, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": -0.0959, \"times_seen\": 9.0}, {\"site\": 36, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"36\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"*\", \"escape\": 0.01342691005525626, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.812, \"times_seen\": 2.0}, {\"site\": 37, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"C\", \"escape\": -0.0005624029328322835, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -1.4704, \"times_seen\": 1.0}, {\"site\": 37, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.2193, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"F\", \"escape\": 0.001882156669212556, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -0.9055, \"times_seen\": 5.0}, {\"site\": 37, \"mutant\": \"H\", \"escape\": -0.02836039289481781, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -0.2204, \"times_seen\": 18.0}, {\"site\": 37, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -3.1105, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"L\", \"escape\": 0.017055556352732724, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.3453, \"times_seen\": 2.0}, {\"site\": 37, \"mutant\": \"N\", \"escape\": -0.00947513332542744, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": -2.9696, \"times_seen\": 2.0}, {\"site\": 37, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"37\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -2.77, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"C\", \"escape\": -0.049022717941790125, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -2.6265, \"times_seen\": 3.0}, {\"site\": 38, \"mutant\": \"F\", \"escape\": -0.011948016857624493, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -0.0741, \"times_seen\": 4.0}, {\"site\": 38, \"mutant\": \"H\", \"escape\": 0.0025134502088366224, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -1.4529, \"times_seen\": 5.0}, {\"site\": 38, \"mutant\": \"L\", \"escape\": -0.009890962685517805, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -0.5605, \"times_seen\": 3.0}, {\"site\": 38, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -1.4117, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"38\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 39, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 39, \"mutant\": \"A\", \"escape\": -0.003037094203490936, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.37, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"G\", \"escape\": -0.006190490865429027, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.2309, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"H\", \"escape\": 0.010379334005407255, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.2172, \"times_seen\": 4.0}, {\"site\": 39, \"mutant\": \"L\", \"escape\": 0.026646125008577822, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -1.6753, \"times_seen\": 4.0}, {\"site\": 39, \"mutant\": \"N\", \"escape\": -0.004421699635068565, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": 0.35, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 39, \"mutant\": \"R\", \"escape\": -0.0026934692002565153, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -1.1557, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"S\", \"escape\": -0.015585599046771974, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": 0.3631, \"times_seen\": 36.0}, {\"site\": 39, \"mutant\": \"T\", \"escape\": -0.0013435792915904472, \"epitope\": \"epitope 1\", \"reference_site\": \"39\", \"functional effect\": -0.0649, \"times_seen\": 20.0}, {\"site\": 40, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 40, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 40, \"mutant\": \"E\", \"escape\": 0.034914210225112104, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.0319, \"times_seen\": 5.0}, {\"site\": 40, \"mutant\": \"G\", \"escape\": 0.027615641189458646, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.0019, \"times_seen\": 2.0}, {\"site\": 40, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.4397, \"times_seen\": null}, {\"site\": 40, \"mutant\": \"N\", \"escape\": 2.6046964367819374, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -0.6738, \"times_seen\": 6.0}, {\"site\": 40, \"mutant\": \"Y\", \"escape\": 0.06181153801220437, \"epitope\": \"epitope 1\", \"reference_site\": \"40\", \"functional effect\": -2.2738, \"times_seen\": 1.0}, {\"site\": 41, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 41, \"mutant\": \"E\", \"escape\": 0.012229514209269121, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.6505, \"times_seen\": 12.0}, {\"site\": 41, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 41, \"mutant\": \"I\", \"escape\": 0.013157305897905655, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.4399, \"times_seen\": 8.0}, {\"site\": 41, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 41, \"mutant\": \"M\", \"escape\": -0.009850245900953028, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.3101, \"times_seen\": 1.0}, {\"site\": 41, \"mutant\": \"N\", \"escape\": -0.030220437840963073, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": 0.1298, \"times_seen\": 29.0}, {\"site\": 41, \"mutant\": \"P\", \"escape\": -0.0023990496105714253, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.2988, \"times_seen\": 2.0}, {\"site\": 41, \"mutant\": \"Q\", \"escape\": 0.041001486441586674, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.2941, \"times_seen\": 11.0}, {\"site\": 41, \"mutant\": \"R\", \"escape\": -0.0032956184246235314, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.0335, \"times_seen\": 25.0}, {\"site\": 41, \"mutant\": \"T\", \"escape\": -0.0007587402511561382, \"epitope\": \"epitope 1\", \"reference_site\": \"41\", \"functional effect\": -0.6873, \"times_seen\": 1.0}, {\"site\": 42, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 42, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -3.3265, \"times_seen\": null}, {\"site\": 42, \"mutant\": \"E\", \"escape\": 0.03199745483468641, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -2.0016, \"times_seen\": 2.0}, {\"site\": 42, \"mutant\": \"F\", \"escape\": -0.01504753719297537, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 42, \"mutant\": \"I\", \"escape\": -0.08378652510564237, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.3356, \"times_seen\": 25.0}, {\"site\": 42, \"mutant\": \"L\", \"escape\": -0.010674981020386486, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.3644, \"times_seen\": 4.0}, {\"site\": 42, \"mutant\": \"M\", \"escape\": -0.005602119203174662, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.0304, \"times_seen\": 5.0}, {\"site\": 42, \"mutant\": \"Q\", \"escape\": -0.04065378822506321, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -1.3902, \"times_seen\": 6.0}, {\"site\": 42, \"mutant\": \"R\", \"escape\": -0.00716033966067515, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -0.8912, \"times_seen\": 1.0}, {\"site\": 42, \"mutant\": \"S\", \"escape\": -0.0058961993320833335, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": -0.3052, \"times_seen\": 4.0}, {\"site\": 42, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"42\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": -3.1126, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": -2.939, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": -2.9977, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"Y\", \"escape\": 0.8325199178715645, \"epitope\": \"epitope 1\", \"reference_site\": \"43\", \"functional effect\": 0.171, \"times_seen\": 8.0}, {\"site\": 44, \"mutant\": \"G\", \"escape\": -0.03780699599045184, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -3.1109, \"times_seen\": 2.0}, {\"site\": 44, \"mutant\": \"I\", \"escape\": -0.0016657553632189869, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -2.5511, \"times_seen\": 1.0}, {\"site\": 44, \"mutant\": \"K\", \"escape\": 0.009058942924183248, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -1.3754, \"times_seen\": 14.0}, {\"site\": 44, \"mutant\": \"M\", \"escape\": -0.002782642746760414, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -1.3611, \"times_seen\": 3.0}, {\"site\": 44, \"mutant\": \"Q\", \"escape\": 0.0021826367773201635, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -1.7575, \"times_seen\": 4.0}, {\"site\": 44, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 44, \"mutant\": \"S\", \"escape\": 0.014184873445704831, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": -2.5003, \"times_seen\": 2.0}, {\"site\": 44, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"44\", \"functional effect\": 0.0669, \"times_seen\": null}, {\"site\": 45, \"mutant\": \"A\", \"escape\": 0.003660353044440912, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": 0.032, \"times_seen\": 15.0}, {\"site\": 45, \"mutant\": \"F\", \"escape\": -0.06620335841941022, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.6868, \"times_seen\": 35.0}, {\"site\": 45, \"mutant\": \"I\", \"escape\": 0.022014621667797458, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.596, \"times_seen\": 5.0}, {\"site\": 45, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": 0.1193, \"times_seen\": null}, {\"site\": 45, \"mutant\": \"P\", \"escape\": -0.25217252437711946, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -1.1187, \"times_seen\": 26.0}, {\"site\": 45, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 45, \"mutant\": \"T\", \"escape\": 0.1887412288117679, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.5499, \"times_seen\": 36.0}, {\"site\": 45, \"mutant\": \"Y\", \"escape\": -0.022846461957136723, \"epitope\": \"epitope 1\", \"reference_site\": \"45\", \"functional effect\": -0.2105, \"times_seen\": 20.0}, {\"site\": 46, \"mutant\": \"A\", \"escape\": -1.74321155741258, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.0387, \"times_seen\": 4.0}, {\"site\": 46, \"mutant\": \"C\", \"escape\": -0.012090873496710576, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -2.7094, \"times_seen\": 1.0}, {\"site\": 46, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -0.3882, \"times_seen\": null}, {\"site\": 46, \"mutant\": \"L\", \"escape\": 0.00898738699627582, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -0.1556, \"times_seen\": 4.0}, {\"site\": 46, \"mutant\": \"P\", \"escape\": -0.07136255385322848, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -2.2301, \"times_seen\": 12.0}, {\"site\": 46, \"mutant\": \"Q\", \"escape\": -0.009508406831460661, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -0.9944, \"times_seen\": 4.0}, {\"site\": 46, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 46, \"mutant\": \"T\", \"escape\": -0.004536493669614207, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 46, \"mutant\": \"W\", \"escape\": 0.0838250926779246, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": -2.5774, \"times_seen\": 17.0}, {\"site\": 46, \"mutant\": \"Y\", \"escape\": 0.008193103483468106, \"epitope\": \"epitope 1\", \"reference_site\": \"46\", \"functional effect\": 0.0297, \"times_seen\": 5.0}, {\"site\": 47, \"mutant\": \"A\", \"escape\": 0.02524534960655079, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.1629, \"times_seen\": 6.0}, {\"site\": 47, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -3.0776, \"times_seen\": null}, {\"site\": 47, \"mutant\": \"F\", \"escape\": -0.0008694016023284345, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.5387, \"times_seen\": 11.0}, {\"site\": 47, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -1.3525, \"times_seen\": null}, {\"site\": 47, \"mutant\": \"I\", \"escape\": 0.20545849784227488, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.4671, \"times_seen\": 2.0}, {\"site\": 47, \"mutant\": \"L\", \"escape\": -0.055196605987008304, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.1979, \"times_seen\": 30.0}, {\"site\": 47, \"mutant\": \"M\", \"escape\": -0.011944084248404223, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.3864, \"times_seen\": 5.0}, {\"site\": 47, \"mutant\": \"R\", \"escape\": -0.0181217996561076, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.1746, \"times_seen\": 7.0}, {\"site\": 47, \"mutant\": \"S\", \"escape\": -0.0032359766093116482, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.2582, \"times_seen\": 2.0}, {\"site\": 47, \"mutant\": \"T\", \"escape\": -0.6113357081946729, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": -0.0317, \"times_seen\": 3.0}, {\"site\": 47, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"47\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 48, \"mutant\": \"F\", \"escape\": -0.005938668675883972, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.8417, \"times_seen\": 2.0}, {\"site\": 48, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 48, \"mutant\": \"M\", \"escape\": 0.0003862386428318851, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.2817, \"times_seen\": 3.0}, {\"site\": 48, \"mutant\": \"P\", \"escape\": -0.05863947300854744, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -1.8053, \"times_seen\": 10.0}, {\"site\": 48, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -2.8194, \"times_seen\": null}, {\"site\": 48, \"mutant\": \"R\", \"escape\": -0.007273052190246793, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.17, \"times_seen\": 2.0}, {\"site\": 48, \"mutant\": \"T\", \"escape\": 0.010813891688916562, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.3694, \"times_seen\": 2.0}, {\"site\": 48, \"mutant\": \"V\", \"escape\": -0.0036670380112421115, \"epitope\": \"epitope 1\", \"reference_site\": \"48\", \"functional effect\": -0.6601, \"times_seen\": 2.0}, {\"site\": 49, \"mutant\": \"A\", \"escape\": 0.0012249460554673087, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.2204, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"C\", \"escape\": 0.07063558016360577, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.2969, \"times_seen\": 21.0}, {\"site\": 49, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -1.9489, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"I\", \"escape\": -0.012214039598174565, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 49, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -1.1338, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"L\", \"escape\": 0.01021567186959608, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.0998, \"times_seen\": 20.0}, {\"site\": 49, \"mutant\": \"N\", \"escape\": -0.0035427949745026064, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -2.7292, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"P\", \"escape\": 0.01833791416067965, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -2.5739, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"Q\", \"escape\": 0.09964125162640357, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.0067, \"times_seen\": 39.0}, {\"site\": 49, \"mutant\": \"R\", \"escape\": -0.04267005425327803, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 49, \"mutant\": \"S\", \"escape\": 0.0542067889325575, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -1.4669, \"times_seen\": 3.0}, {\"site\": 49, \"mutant\": \"T\", \"escape\": -0.0071954072304954205, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.026, \"times_seen\": 3.0}, {\"site\": 49, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.3197, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"W\", \"escape\": 0.012643981496317177, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": 0.2159, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"Y\", \"escape\": -0.010209355472722169, \"epitope\": \"epitope 1\", \"reference_site\": \"49\", \"functional effect\": -0.1723, \"times_seen\": 20.0}, {\"site\": 50, \"mutant\": \"A\", \"escape\": -0.007864947435226798, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0423, \"times_seen\": 2.0}, {\"site\": 50, \"mutant\": \"C\", \"escape\": -0.0028076402762103434, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.5661, \"times_seen\": 2.0}, {\"site\": 50, \"mutant\": \"F\", \"escape\": -0.020099572801235196, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.3996, \"times_seen\": 10.0}, {\"site\": 50, \"mutant\": \"G\", \"escape\": 0.04810767314248835, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.0512, \"times_seen\": 20.0}, {\"site\": 50, \"mutant\": \"I\", \"escape\": -0.002061496253546003, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0653, \"times_seen\": 2.0}, {\"site\": 50, \"mutant\": \"L\", \"escape\": -0.010704321616420143, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.4275, \"times_seen\": 5.0}, {\"site\": 50, \"mutant\": \"N\", \"escape\": 0.5231812417255512, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.1203, \"times_seen\": 45.0}, {\"site\": 50, \"mutant\": \"P\", \"escape\": 0.0409218115382334, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -0.1371, \"times_seen\": 33.0}, {\"site\": 50, \"mutant\": \"R\", \"escape\": -0.004928304007345203, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": -1.2814, \"times_seen\": 7.0}, {\"site\": 50, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 50, \"mutant\": \"T\", \"escape\": -0.0047655902741972535, \"epitope\": \"epitope 1\", \"reference_site\": \"50\", \"functional effect\": 0.0492, \"times_seen\": 9.0}, {\"site\": 51, \"mutant\": \"A\", \"escape\": 0.04821294653801614, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 51, \"mutant\": \"F\", \"escape\": -0.006806668522557884, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 51, \"mutant\": \"I\", \"escape\": -0.019468307284545572, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": -0.0949, \"times_seen\": 24.0}, {\"site\": 51, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": -3.205, \"times_seen\": null}, {\"site\": 51, \"mutant\": \"N\", \"escape\": 0.019480299325166855, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.3228, \"times_seen\": 6.0}, {\"site\": 51, \"mutant\": \"S\", \"escape\": -0.02594214130285938, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.0009, \"times_seen\": 3.0}, {\"site\": 51, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"51\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 52, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": -2.8375, \"times_seen\": null}, {\"site\": 52, \"mutant\": \"E\", \"escape\": 0.07091930608899596, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": -1.0619, \"times_seen\": 22.0}, {\"site\": 52, \"mutant\": \"H\", \"escape\": -0.7503369243096365, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.3659, \"times_seen\": 64.0}, {\"site\": 52, \"mutant\": \"K\", \"escape\": -0.00992477757200563, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.042, \"times_seen\": 6.0}, {\"site\": 52, \"mutant\": \"L\", \"escape\": -0.049601242262684996, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": -0.0164, \"times_seen\": 29.0}, {\"site\": 52, \"mutant\": \"P\", \"escape\": 0.017481509110230973, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.0047, \"times_seen\": 16.0}, {\"site\": 52, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 52, \"mutant\": \"R\", \"escape\": -0.06190665773969882, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.1996, \"times_seen\": 23.0}, {\"site\": 52, \"mutant\": \"S\", \"escape\": 0.02177337015383302, \"epitope\": \"epitope 1\", \"reference_site\": \"52\", \"functional effect\": 0.3851, \"times_seen\": 3.0}, {\"site\": 53, \"mutant\": \"C\", \"escape\": -0.009269970234940006, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": -0.3682, \"times_seen\": 13.0}, {\"site\": 53, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 53, \"mutant\": \"E\", \"escape\": 0.08258231890166949, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.1243, \"times_seen\": 4.0}, {\"site\": 53, \"mutant\": \"G\", \"escape\": 0.05330800341286595, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.0635, \"times_seen\": 34.0}, {\"site\": 53, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": -2.9837, \"times_seen\": null}, {\"site\": 53, \"mutant\": \"N\", \"escape\": -0.15983263445647777, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": 0.0979, \"times_seen\": 173.0}, {\"site\": 53, \"mutant\": \"Y\", \"escape\": 0.005803920431520023, \"epitope\": \"epitope 1\", \"reference_site\": \"53\", \"functional effect\": -2.8725, \"times_seen\": 5.0}, {\"site\": 54, \"mutant\": \"F\", \"escape\": -0.015447093665257774, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.2798, \"times_seen\": 11.0}, {\"site\": 54, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 54, \"mutant\": \"M\", \"escape\": -0.013712645753762073, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": 0.0382, \"times_seen\": 7.0}, {\"site\": 54, \"mutant\": \"P\", \"escape\": 0.3922399358231311, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -2.1354, \"times_seen\": 14.0}, {\"site\": 54, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.3841, \"times_seen\": null}, {\"site\": 54, \"mutant\": \"R\", \"escape\": -0.0016797781502766967, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -1.0069, \"times_seen\": 2.0}, {\"site\": 54, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.3237, \"times_seen\": null}, {\"site\": 54, \"mutant\": \"V\", \"escape\": -0.029521360919845467, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.7697, \"times_seen\": 12.0}, {\"site\": 54, \"mutant\": \"W\", \"escape\": -0.02949474174872378, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": 0.1398, \"times_seen\": 6.0}, {\"site\": 54, \"mutant\": \"Y\", \"escape\": 0.02453517972418952, \"epitope\": \"epitope 1\", \"reference_site\": \"54\", \"functional effect\": -0.5728, \"times_seen\": 2.0}, {\"site\": 55, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -2.1941, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"L\", \"escape\": -0.006132134906786919, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -0.7282, \"times_seen\": 2.0}, {\"site\": 55, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -2.7433, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"Y\", \"escape\": -0.05032942668656319, \"epitope\": \"epitope 1\", \"reference_site\": \"55\", \"functional effect\": 0.2628, \"times_seen\": 20.0}, {\"site\": 56, \"mutant\": \"F\", \"escape\": 0.00901344920137262, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -1.7867, \"times_seen\": 6.0}, {\"site\": 56, \"mutant\": \"I\", \"escape\": -0.00023169845586562803, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -0.2693, \"times_seen\": 5.0}, {\"site\": 56, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 56, \"mutant\": \"M\", \"escape\": -0.05210716030282722, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": 0.1187, \"times_seen\": 5.0}, {\"site\": 56, \"mutant\": \"P\", \"escape\": 0.0008120436950211226, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -2.2717, \"times_seen\": 4.0}, {\"site\": 56, \"mutant\": \"Q\", \"escape\": -0.004295425983433425, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -0.3305, \"times_seen\": 1.0}, {\"site\": 56, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -2.7355, \"times_seen\": null}, {\"site\": 56, \"mutant\": \"V\", \"escape\": 0.0004495581128811793, \"epitope\": \"epitope 1\", \"reference_site\": \"56\", \"functional effect\": -0.0474, \"times_seen\": 13.0}, {\"site\": 57, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -0.9319, \"times_seen\": null}, {\"site\": 57, \"mutant\": \"L\", \"escape\": -0.00218324586322562, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -2.8649, \"times_seen\": 1.0}, {\"site\": 57, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 57, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -2.3902, \"times_seen\": null}, {\"site\": 57, \"mutant\": \"S\", \"escape\": 0.008735556874323971, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -1.402, \"times_seen\": 12.0}, {\"site\": 57, \"mutant\": \"T\", \"escape\": 0.013552177904729977, \"epitope\": \"epitope 1\", \"reference_site\": \"57\", \"functional effect\": -1.9551, \"times_seen\": 2.0}, {\"site\": 58, \"mutant\": \"C\", \"escape\": 0.04109787180818309, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -2.9909, \"times_seen\": 3.0}, {\"site\": 58, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 58, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 58, \"mutant\": \"L\", \"escape\": -0.002807323162723111, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -0.6816, \"times_seen\": 10.0}, {\"site\": 58, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -2.9906, \"times_seen\": null}, {\"site\": 58, \"mutant\": \"S\", \"escape\": -0.009149108050112648, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -1.1986, \"times_seen\": 4.0}, {\"site\": 58, \"mutant\": \"V\", \"escape\": 0.03808439907063411, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": -1.701, \"times_seen\": 1.0}, {\"site\": 58, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"58\", \"functional effect\": 0.0307, \"times_seen\": null}, {\"site\": 59, \"mutant\": \"C\", \"escape\": -0.004414331998825889, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -0.1, \"times_seen\": 1.0}, {\"site\": 59, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 59, \"mutant\": \"I\", \"escape\": 0.013457472366836318, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -2.142, \"times_seen\": 1.0}, {\"site\": 59, \"mutant\": \"L\", \"escape\": -0.1017661465620335, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -0.1372, \"times_seen\": 28.0}, {\"site\": 59, \"mutant\": \"S\", \"escape\": -0.03253579470160912, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": 0.2057, \"times_seen\": 24.0}, {\"site\": 59, \"mutant\": \"Y\", \"escape\": -0.020131804539215273, \"epitope\": \"epitope 1\", \"reference_site\": \"59\", \"functional effect\": -0.0095, \"times_seen\": 35.0}, {\"site\": 60, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -2.3603, \"times_seen\": null}, {\"site\": 60, \"mutant\": \"A\", \"escape\": 0.004385676886964884, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.2894, \"times_seen\": 15.0}, {\"site\": 60, \"mutant\": \"C\", \"escape\": 0.004478675622571732, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.4102, \"times_seen\": 18.0}, {\"site\": 60, \"mutant\": \"F\", \"escape\": 0.008311065679864891, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -1.6135, \"times_seen\": 34.0}, {\"site\": 60, \"mutant\": \"G\", \"escape\": -0.006310327871621242, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.4363, \"times_seen\": 12.0}, {\"site\": 60, \"mutant\": \"I\", \"escape\": -0.005186007231954047, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.5157, \"times_seen\": 2.0}, {\"site\": 60, \"mutant\": \"L\", \"escape\": -0.005021057069052207, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -2.112, \"times_seen\": 2.0}, {\"site\": 60, \"mutant\": \"N\", \"escape\": 0.019174011113030347, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.3375, \"times_seen\": 15.0}, {\"site\": 60, \"mutant\": \"P\", \"escape\": -0.00355359939886429, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -2.9879, \"times_seen\": 1.0}, {\"site\": 60, \"mutant\": \"R\", \"escape\": -0.024065116378201242, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -1.0799, \"times_seen\": 3.0}, {\"site\": 60, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 60, \"mutant\": \"T\", \"escape\": -0.029079572423427312, \"epitope\": \"epitope 1\", \"reference_site\": \"60\", \"functional effect\": -0.0547, \"times_seen\": 21.0}, {\"site\": 61, \"mutant\": \"D\", \"escape\": 0.011395394728105376, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.1119, \"times_seen\": 8.0}, {\"site\": 61, \"mutant\": \"H\", \"escape\": -0.013244703467642236, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.192, \"times_seen\": 7.0}, {\"site\": 61, \"mutant\": \"K\", \"escape\": -0.0005913896432598852, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.1077, \"times_seen\": 29.0}, {\"site\": 61, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 61, \"mutant\": \"S\", \"escape\": -0.0927261223002551, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.2256, \"times_seen\": 16.0}, {\"site\": 61, \"mutant\": \"T\", \"escape\": 0.007752037726314863, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -0.0966, \"times_seen\": 16.0}, {\"site\": 61, \"mutant\": \"W\", \"escape\": 0.0050644400792976335, \"epitope\": \"epitope 1\", \"reference_site\": \"61\", \"functional effect\": -1.2228, \"times_seen\": 5.0}, {\"site\": 62, \"mutant\": \"-\", \"escape\": 0.06530968517206429, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -1.2254, \"times_seen\": 6.0}, {\"site\": 62, \"mutant\": \"A\", \"escape\": 0.0034691561376907457, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -0.5063, \"times_seen\": 18.0}, {\"site\": 62, \"mutant\": \"D\", \"escape\": -0.002860833687772971, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -2.1029, \"times_seen\": 2.0}, {\"site\": 62, \"mutant\": \"E\", \"escape\": -0.0010615664364032895, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -2.957, \"times_seen\": 1.0}, {\"site\": 62, \"mutant\": \"F\", \"escape\": -0.014145628060750646, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -1.0437, \"times_seen\": 30.0}, {\"site\": 62, \"mutant\": \"G\", \"escape\": 0.00022335714871571616, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -0.8009, \"times_seen\": 11.0}, {\"site\": 62, \"mutant\": \"I\", \"escape\": 0.6505606888241299, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": 0.0795, \"times_seen\": 54.0}, {\"site\": 62, \"mutant\": \"L\", \"escape\": 0.04276261620668697, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": -0.0591, \"times_seen\": 84.0}, {\"site\": 62, \"mutant\": \"M\", \"escape\": 0.1826865589139768, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": 0.0445, \"times_seen\": 21.0}, {\"site\": 62, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"62\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 63, \"mutant\": \"-\", \"escape\": -0.004345889135643493, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1452, \"times_seen\": 15.0}, {\"site\": 63, \"mutant\": \"A\", \"escape\": -0.006227780935044735, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1278, \"times_seen\": 16.0}, {\"site\": 63, \"mutant\": \"I\", \"escape\": -0.06299379433909931, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.3034, \"times_seen\": 50.0}, {\"site\": 63, \"mutant\": \"L\", \"escape\": -0.016486320737256924, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.7167, \"times_seen\": 5.0}, {\"site\": 63, \"mutant\": \"N\", \"escape\": 0.08219031995044747, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1516, \"times_seen\": 24.0}, {\"site\": 63, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 63, \"mutant\": \"Q\", \"escape\": 0.02791840610084318, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.2228, \"times_seen\": 5.0}, {\"site\": 63, \"mutant\": \"S\", \"escape\": 0.07881507072238689, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": -0.1262, \"times_seen\": 17.0}, {\"site\": 63, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"63\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 64, \"mutant\": \"*\", \"escape\": -0.00961630956637072, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -2.6819, \"times_seen\": 2.0}, {\"site\": 64, \"mutant\": \"-\", \"escape\": -1.9983346982217491, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.1828, \"times_seen\": 20.0}, {\"site\": 64, \"mutant\": \"C\", \"escape\": 0.012867052101375202, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.0504, \"times_seen\": 94.0}, {\"site\": 64, \"mutant\": \"F\", \"escape\": 0.07254295560412653, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.0032, \"times_seen\": 19.0}, {\"site\": 64, \"mutant\": \"G\", \"escape\": -0.023378605103536704, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.0158, \"times_seen\": 15.0}, {\"site\": 64, \"mutant\": \"K\", \"escape\": 0.039396395262025936, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.1005, \"times_seen\": 23.0}, {\"site\": 64, \"mutant\": \"L\", \"escape\": 0.0029342738917700175, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.0708, \"times_seen\": 101.0}, {\"site\": 64, \"mutant\": \"R\", \"escape\": -0.20044561151020104, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.1623, \"times_seen\": 122.0}, {\"site\": 64, \"mutant\": \"S\", \"escape\": 0.004743961841675924, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": -0.0457, \"times_seen\": 20.0}, {\"site\": 64, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"64\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 65, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 65, \"mutant\": \"-\", \"escape\": -0.03387355708537189, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.2061, \"times_seen\": 17.0}, {\"site\": 65, \"mutant\": \"C\", \"escape\": -0.8187909550258592, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.2315, \"times_seen\": 24.0}, {\"site\": 65, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 65, \"mutant\": \"I\", \"escape\": -0.0068703571942183555, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.1169, \"times_seen\": 1.0}, {\"site\": 65, \"mutant\": \"L\", \"escape\": 0.019218104616989817, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.0363, \"times_seen\": 31.0}, {\"site\": 65, \"mutant\": \"S\", \"escape\": 0.02310042738585583, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.5773, \"times_seen\": 14.0}, {\"site\": 65, \"mutant\": \"V\", \"escape\": 0.006424548912330563, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": 0.0132, \"times_seen\": 9.0}, {\"site\": 65, \"mutant\": \"Y\", \"escape\": -0.012948293928075524, \"epitope\": \"epitope 1\", \"reference_site\": \"65\", \"functional effect\": -0.1808, \"times_seen\": 35.0}, {\"site\": 66, \"mutant\": \"-\", \"escape\": 0.09282023014931398, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.1132, \"times_seen\": 30.0}, {\"site\": 66, \"mutant\": \"D\", \"escape\": 0.02415609643462452, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.0423, \"times_seen\": 15.0}, {\"site\": 66, \"mutant\": \"F\", \"escape\": 0.039399382012387414, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.113, \"times_seen\": 26.0}, {\"site\": 66, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 66, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 66, \"mutant\": \"M\", \"escape\": -0.055767028034267044, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.0595, \"times_seen\": 24.0}, {\"site\": 66, \"mutant\": \"N\", \"escape\": -0.17548227087358081, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.1133, \"times_seen\": 44.0}, {\"site\": 66, \"mutant\": \"P\", \"escape\": -0.00531790525035231, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.1817, \"times_seen\": 13.0}, {\"site\": 66, \"mutant\": \"Q\", \"escape\": -0.03444920517788945, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.0272, \"times_seen\": 15.0}, {\"site\": 66, \"mutant\": \"R\", \"escape\": -0.2768101293115166, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": -0.0116, \"times_seen\": 39.0}, {\"site\": 66, \"mutant\": \"Y\", \"escape\": -0.13892465424290443, \"epitope\": \"epitope 1\", \"reference_site\": \"66\", \"functional effect\": 0.1116, \"times_seen\": 117.0}, {\"site\": 67, \"mutant\": \"*\", \"escape\": -0.008970777876866592, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -2.6734, \"times_seen\": 5.0}, {\"site\": 67, \"mutant\": \"-\", \"escape\": -0.08129495426406222, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.1529, \"times_seen\": 19.0}, {\"site\": 67, \"mutant\": \"A\", \"escape\": -0.08842192187347801, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.1023, \"times_seen\": 220.0}, {\"site\": 67, \"mutant\": \"C\", \"escape\": 0.024156886741982925, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.3216, \"times_seen\": 99.0}, {\"site\": 67, \"mutant\": \"D\", \"escape\": -2.601801089373514, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.033, \"times_seen\": 115.0}, {\"site\": 67, \"mutant\": \"E\", \"escape\": 0.05548555463983184, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0541, \"times_seen\": 110.0}, {\"site\": 67, \"mutant\": \"F\", \"escape\": -0.9961990816421733, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0415, \"times_seen\": 89.0}, {\"site\": 67, \"mutant\": \"G\", \"escape\": 0.008263690482135714, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0284, \"times_seen\": 116.0}, {\"site\": 67, \"mutant\": \"H\", \"escape\": 0.012405279899016852, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0483, \"times_seen\": 63.0}, {\"site\": 67, \"mutant\": \"I\", \"escape\": 0.5647976574825443, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0065, \"times_seen\": 106.0}, {\"site\": 67, \"mutant\": \"K\", \"escape\": -0.106860291931243, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.3331, \"times_seen\": 58.0}, {\"site\": 67, \"mutant\": \"L\", \"escape\": -0.1029490360603418, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0207, \"times_seen\": 188.0}, {\"site\": 67, \"mutant\": \"M\", \"escape\": 0.3054844836827236, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0777, \"times_seen\": 82.0}, {\"site\": 67, \"mutant\": \"N\", \"escape\": 0.01880417563052847, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0498, \"times_seen\": 68.0}, {\"site\": 67, \"mutant\": \"P\", \"escape\": 0.106797274027475, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0876, \"times_seen\": 152.0}, {\"site\": 67, \"mutant\": \"Q\", \"escape\": 0.007543205593450116, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0541, \"times_seen\": 57.0}, {\"site\": 67, \"mutant\": \"R\", \"escape\": 0.03649800441764022, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.1584, \"times_seen\": 122.0}, {\"site\": 67, \"mutant\": \"S\", \"escape\": -0.009333359375597055, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0764, \"times_seen\": 270.0}, {\"site\": 67, \"mutant\": \"T\", \"escape\": -0.19392241257849574, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0328, \"times_seen\": 193.0}, {\"site\": 67, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 67, \"mutant\": \"W\", \"escape\": -0.09608550538662956, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": 0.0267, \"times_seen\": 63.0}, {\"site\": 67, \"mutant\": \"Y\", \"escape\": -0.10346463738803652, \"epitope\": \"epitope 1\", \"reference_site\": \"67\", \"functional effect\": -0.0282, \"times_seen\": 63.0}, {\"site\": 68, \"mutant\": \"-\", \"escape\": -0.06162718357176008, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0795, \"times_seen\": 15.0}, {\"site\": 68, \"mutant\": \"C\", \"escape\": -0.02023775270632127, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.008, \"times_seen\": 11.0}, {\"site\": 68, \"mutant\": \"F\", \"escape\": -0.0163529755386173, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.1689, \"times_seen\": 16.0}, {\"site\": 68, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 68, \"mutant\": \"K\", \"escape\": -0.012246678514340702, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.2093, \"times_seen\": 7.0}, {\"site\": 68, \"mutant\": \"L\", \"escape\": 0.013377416231927739, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.2424, \"times_seen\": 25.0}, {\"site\": 68, \"mutant\": \"M\", \"escape\": 0.045146977337420124, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0642, \"times_seen\": 37.0}, {\"site\": 68, \"mutant\": \"N\", \"escape\": -0.030799834763547883, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.1163, \"times_seen\": 16.0}, {\"site\": 68, \"mutant\": \"R\", \"escape\": -0.01730858571827858, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.094, \"times_seen\": 22.0}, {\"site\": 68, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.4954, \"times_seen\": null}, {\"site\": 68, \"mutant\": \"T\", \"escape\": -0.2184021436207775, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0391, \"times_seen\": 106.0}, {\"site\": 68, \"mutant\": \"V\", \"escape\": -9.673573851300023e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": -0.0412, \"times_seen\": 23.0}, {\"site\": 68, \"mutant\": \"Y\", \"escape\": -0.0054466422475924915, \"epitope\": \"epitope 1\", \"reference_site\": \"68\", \"functional effect\": 0.0902, \"times_seen\": 19.0}, {\"site\": 69, \"mutant\": \"-\", \"escape\": 0.1831188642434197, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0673, \"times_seen\": 21.0}, {\"site\": 69, \"mutant\": \"A\", \"escape\": 0.45967543913963743, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.1456, \"times_seen\": 56.0}, {\"site\": 69, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": -0.1804, \"times_seen\": null}, {\"site\": 69, \"mutant\": \"E\", \"escape\": 0.008611084635082138, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.3574, \"times_seen\": 8.0}, {\"site\": 69, \"mutant\": \"F\", \"escape\": 0.018816225719507487, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0848, \"times_seen\": 63.0}, {\"site\": 69, \"mutant\": \"L\", \"escape\": 0.009791557611709413, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": -0.0858, \"times_seen\": 12.0}, {\"site\": 69, \"mutant\": \"P\", \"escape\": 0.0256407110044369, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0396, \"times_seen\": 69.0}, {\"site\": 69, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 69, \"mutant\": \"T\", \"escape\": -0.019067192999979176, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.0112, \"times_seen\": 15.0}, {\"site\": 69, \"mutant\": \"V\", \"escape\": -0.0007093076782897724, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.04, \"times_seen\": 12.0}, {\"site\": 69, \"mutant\": \"Y\", \"escape\": -0.13329832146946766, \"epitope\": \"epitope 1\", \"reference_site\": \"71\", \"functional effect\": 0.1375, \"times_seen\": 93.0}, {\"site\": 70, \"mutant\": \"-\", \"escape\": -0.036127727376526336, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.1119, \"times_seen\": 16.0}, {\"site\": 70, \"mutant\": \"A\", \"escape\": 0.22954959254031296, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.0703, \"times_seen\": 41.0}, {\"site\": 70, \"mutant\": \"C\", \"escape\": -0.006329374876086664, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.105, \"times_seen\": 3.0}, {\"site\": 70, \"mutant\": \"D\", \"escape\": 0.004312520150684586, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.0347, \"times_seen\": 25.0}, {\"site\": 70, \"mutant\": \"E\", \"escape\": -0.006018500419143317, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.0627, \"times_seen\": 22.0}, {\"site\": 70, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 70, \"mutant\": \"R\", \"escape\": -0.010293269168145883, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.3069, \"times_seen\": 24.0}, {\"site\": 70, \"mutant\": \"S\", \"escape\": 0.03531715663144193, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": 0.021, \"times_seen\": 9.0}, {\"site\": 70, \"mutant\": \"V\", \"escape\": 0.009362412031326487, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.0736, \"times_seen\": 35.0}, {\"site\": 70, \"mutant\": \"W\", \"escape\": -0.020917897343249756, \"epitope\": \"epitope 1\", \"reference_site\": \"72\", \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 71, \"mutant\": \"-\", \"escape\": 0.014027853391839255, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.1346, \"times_seen\": 16.0}, {\"site\": 71, \"mutant\": \"A\", \"escape\": -0.012833652933702238, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": -0.126, \"times_seen\": 6.0}, {\"site\": 71, \"mutant\": \"I\", \"escape\": 0.004760794806263011, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0507, \"times_seen\": 48.0}, {\"site\": 71, \"mutant\": \"L\", \"escape\": -0.059739188375993346, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0925, \"times_seen\": 16.0}, {\"site\": 71, \"mutant\": \"N\", \"escape\": 0.032354041920587114, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": -0.0987, \"times_seen\": 21.0}, {\"site\": 71, \"mutant\": \"P\", \"escape\": -0.016993529460912118, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0129, \"times_seen\": 13.0}, {\"site\": 71, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": -0.0436, \"times_seen\": null}, {\"site\": 71, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"73\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 72, \"mutant\": \"-\", \"escape\": 0.06075816375679481, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.0354, \"times_seen\": 19.0}, {\"site\": 72, \"mutant\": \"D\", \"escape\": -0.028453056913131866, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.1093, \"times_seen\": 11.0}, {\"site\": 72, \"mutant\": \"H\", \"escape\": 0.01235602309262208, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0324, \"times_seen\": 18.0}, {\"site\": 72, \"mutant\": \"I\", \"escape\": 0.037065661287465246, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.0269, \"times_seen\": 15.0}, {\"site\": 72, \"mutant\": \"K\", \"escape\": 0.02964760341522398, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.0726, \"times_seen\": 24.0}, {\"site\": 72, \"mutant\": \"M\", \"escape\": 0.011048008748318575, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0406, \"times_seen\": 10.0}, {\"site\": 72, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 72, \"mutant\": \"S\", \"escape\": 0.03174343304895507, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": -0.1336, \"times_seen\": 11.0}, {\"site\": 72, \"mutant\": \"T\", \"escape\": -0.010780227696848005, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.0316, \"times_seen\": 12.0}, {\"site\": 72, \"mutant\": \"Y\", \"escape\": -0.012109309360183274, \"epitope\": \"epitope 1\", \"reference_site\": \"74\", \"functional effect\": 0.2905, \"times_seen\": 5.0}, {\"site\": 73, \"mutant\": \"*\", \"escape\": 0.00965833179795701, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": -2.6083, \"times_seen\": 4.0}, {\"site\": 73, \"mutant\": \"-\", \"escape\": -0.004992109495057374, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.068, \"times_seen\": 24.0}, {\"site\": 73, \"mutant\": \"A\", \"escape\": -0.39754318945811085, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0017, \"times_seen\": 177.0}, {\"site\": 73, \"mutant\": \"C\", \"escape\": -0.004681356792661199, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.005, \"times_seen\": 140.0}, {\"site\": 73, \"mutant\": \"D\", \"escape\": 0.06182240198992432, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1365, \"times_seen\": 192.0}, {\"site\": 73, \"mutant\": \"E\", \"escape\": 0.5858844546055377, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1601, \"times_seen\": 41.0}, {\"site\": 73, \"mutant\": \"F\", \"escape\": 0.057742348208874195, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0954, \"times_seen\": 53.0}, {\"site\": 73, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 73, \"mutant\": \"H\", \"escape\": 0.012031981653258392, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0146, \"times_seen\": 36.0}, {\"site\": 73, \"mutant\": \"I\", \"escape\": 0.13964598365305156, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1174, \"times_seen\": 59.0}, {\"site\": 73, \"mutant\": \"K\", \"escape\": -0.04042952911852141, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0065, \"times_seen\": 29.0}, {\"site\": 73, \"mutant\": \"L\", \"escape\": -0.15014244236905575, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0908, \"times_seen\": 113.0}, {\"site\": 73, \"mutant\": \"M\", \"escape\": -0.05715320808093039, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0553, \"times_seen\": 37.0}, {\"site\": 73, \"mutant\": \"N\", \"escape\": 0.009274823492089069, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0523, \"times_seen\": 81.0}, {\"site\": 73, \"mutant\": \"P\", \"escape\": 0.09006942200816803, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0268, \"times_seen\": 92.0}, {\"site\": 73, \"mutant\": \"Q\", \"escape\": 0.002065256996976459, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1306, \"times_seen\": 24.0}, {\"site\": 73, \"mutant\": \"R\", \"escape\": 0.18156434191689766, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": -0.1142, \"times_seen\": 145.0}, {\"site\": 73, \"mutant\": \"S\", \"escape\": 0.10356303723196546, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0969, \"times_seen\": 255.0}, {\"site\": 73, \"mutant\": \"T\", \"escape\": -0.11913215230835747, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0799, \"times_seen\": 89.0}, {\"site\": 73, \"mutant\": \"V\", \"escape\": 0.06946559108161267, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0418, \"times_seen\": 159.0}, {\"site\": 73, \"mutant\": \"W\", \"escape\": -0.026730152784467824, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.1616, \"times_seen\": 39.0}, {\"site\": 73, \"mutant\": \"Y\", \"escape\": -0.13911574000169682, \"epitope\": \"epitope 1\", \"reference_site\": \"75\", \"functional effect\": 0.0413, \"times_seen\": 39.0}, {\"site\": 74, \"mutant\": \"*\", \"escape\": -0.24859429991610035, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -2.5774, \"times_seen\": 7.0}, {\"site\": 74, \"mutant\": \"-\", \"escape\": -0.020713539168639262, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0534, \"times_seen\": 16.0}, {\"site\": 74, \"mutant\": \"A\", \"escape\": -0.02843162349087792, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0788, \"times_seen\": 136.0}, {\"site\": 74, \"mutant\": \"C\", \"escape\": -0.025910467704307504, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.1474, \"times_seen\": 29.0}, {\"site\": 74, \"mutant\": \"D\", \"escape\": -0.04958883855094779, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0387, \"times_seen\": 38.0}, {\"site\": 74, \"mutant\": \"E\", \"escape\": -0.06416123288312474, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.062, \"times_seen\": 34.0}, {\"site\": 74, \"mutant\": \"F\", \"escape\": 0.069041468068335, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0331, \"times_seen\": 56.0}, {\"site\": 74, \"mutant\": \"G\", \"escape\": 0.13855665272099876, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0309, \"times_seen\": 53.0}, {\"site\": 74, \"mutant\": \"H\", \"escape\": 0.3542303471325596, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0401, \"times_seen\": 87.0}, {\"site\": 74, \"mutant\": \"I\", \"escape\": 0.6525249441365061, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0742, \"times_seen\": 206.0}, {\"site\": 74, \"mutant\": \"K\", \"escape\": 0.0647016616661198, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.1361, \"times_seen\": 65.0}, {\"site\": 74, \"mutant\": \"L\", \"escape\": 0.1605427468425811, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0384, \"times_seen\": 145.0}, {\"site\": 74, \"mutant\": \"M\", \"escape\": 0.014070585780416334, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0083, \"times_seen\": 43.0}, {\"site\": 74, \"mutant\": \"N\", \"escape\": 0.022439403875807378, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0385, \"times_seen\": 153.0}, {\"site\": 74, \"mutant\": \"P\", \"escape\": -0.0868079223343307, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0178, \"times_seen\": 148.0}, {\"site\": 74, \"mutant\": \"Q\", \"escape\": 0.46394088280951384, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0973, \"times_seen\": 24.0}, {\"site\": 74, \"mutant\": \"R\", \"escape\": 0.3158306232258752, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0877, \"times_seen\": 134.0}, {\"site\": 74, \"mutant\": \"S\", \"escape\": 0.0073536333734608855, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0426, \"times_seen\": 190.0}, {\"site\": 74, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 74, \"mutant\": \"V\", \"escape\": -0.09560496571139349, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0431, \"times_seen\": 93.0}, {\"site\": 74, \"mutant\": \"W\", \"escape\": -0.047968272745248605, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": 0.0581, \"times_seen\": 32.0}, {\"site\": 74, \"mutant\": \"Y\", \"escape\": 0.07840603396049481, \"epitope\": \"epitope 1\", \"reference_site\": \"76\", \"functional effect\": -0.0973, \"times_seen\": 83.0}, {\"site\": 75, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 75, \"mutant\": \"-\", \"escape\": -0.023877777315620775, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0154, \"times_seen\": 16.0}, {\"site\": 75, \"mutant\": \"C\", \"escape\": -0.05600531094866991, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0372, \"times_seen\": 19.0}, {\"site\": 75, \"mutant\": \"E\", \"escape\": 0.00925120359204365, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0428, \"times_seen\": 17.0}, {\"site\": 75, \"mutant\": \"G\", \"escape\": -0.03561240499704462, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 75, \"mutant\": \"I\", \"escape\": 0.012782831063438525, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0788, \"times_seen\": 17.0}, {\"site\": 75, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 75, \"mutant\": \"M\", \"escape\": 0.41462376849281585, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": -0.0458, \"times_seen\": 55.0}, {\"site\": 75, \"mutant\": \"N\", \"escape\": 0.5307658676638619, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0151, \"times_seen\": 72.0}, {\"site\": 75, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 75, \"mutant\": \"R\", \"escape\": 0.050818869621832685, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0427, \"times_seen\": 119.0}, {\"site\": 75, \"mutant\": \"T\", \"escape\": -0.03200719607815861, \"epitope\": \"epitope 1\", \"reference_site\": \"77\", \"functional effect\": 0.0471, \"times_seen\": 42.0}, {\"site\": 76, \"mutant\": \"-\", \"escape\": -0.0426115093424207, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.2354, \"times_seen\": 16.0}, {\"site\": 76, \"mutant\": \"G\", \"escape\": -0.08056307499067715, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.1019, \"times_seen\": 78.0}, {\"site\": 76, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0957, \"times_seen\": null}, {\"site\": 76, \"mutant\": \"K\", \"escape\": 0.020254887973601397, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.1084, \"times_seen\": 114.0}, {\"site\": 76, \"mutant\": \"L\", \"escape\": 0.029408330405340077, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0788, \"times_seen\": 32.0}, {\"site\": 76, \"mutant\": \"M\", \"escape\": 0.17591159128180392, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0973, \"times_seen\": 89.0}, {\"site\": 76, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 76, \"mutant\": \"S\", \"escape\": 0.33896231691299, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.0149, \"times_seen\": 147.0}, {\"site\": 76, \"mutant\": \"T\", \"escape\": -0.016796389965271195, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": 0.093, \"times_seen\": 22.0}, {\"site\": 76, \"mutant\": \"W\", \"escape\": -0.028374594595553058, \"epitope\": \"epitope 1\", \"reference_site\": \"78\", \"functional effect\": -0.0796, \"times_seen\": 44.0}, {\"site\": 77, \"mutant\": \"-\", \"escape\": 0.0030276493183801515, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -0.0415, \"times_seen\": 15.0}, {\"site\": 77, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0182, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.4525, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"L\", \"escape\": -0.01877938312021209, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0478, \"times_seen\": 69.0}, {\"site\": 77, \"mutant\": \"S\", \"escape\": 0.014835264090643261, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -0.0869, \"times_seen\": 28.0}, {\"site\": 77, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -1.6337, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"W\", \"escape\": 0.0043066951185598895, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": -0.1149, \"times_seen\": 16.0}, {\"site\": 77, \"mutant\": \"Y\", \"escape\": 0.007407266440057183, \"epitope\": \"epitope 1\", \"reference_site\": \"79\", \"functional effect\": 0.0759, \"times_seen\": 11.0}, {\"site\": 78, \"mutant\": \"*\", \"escape\": 0.01405176450449566, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -2.1444, \"times_seen\": 2.0}, {\"site\": 78, \"mutant\": \"-\", \"escape\": -0.011504627653184727, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0333, \"times_seen\": 29.0}, {\"site\": 78, \"mutant\": \"A\", \"escape\": -0.17760161673010788, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.059, \"times_seen\": 252.0}, {\"site\": 78, \"mutant\": \"C\", \"escape\": 0.27321447510844504, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0759, \"times_seen\": 60.0}, {\"site\": 78, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 78, \"mutant\": \"E\", \"escape\": 0.08561602973257569, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0457, \"times_seen\": 82.0}, {\"site\": 78, \"mutant\": \"F\", \"escape\": -0.079729090267039, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.2209, \"times_seen\": 95.0}, {\"site\": 78, \"mutant\": \"G\", \"escape\": 0.07029223191079119, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.1373, \"times_seen\": 192.0}, {\"site\": 78, \"mutant\": \"H\", \"escape\": -0.3478240681186083, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0554, \"times_seen\": 193.0}, {\"site\": 78, \"mutant\": \"I\", \"escape\": -0.029161986688374546, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0006, \"times_seen\": 57.0}, {\"site\": 78, \"mutant\": \"K\", \"escape\": 0.04963467700460162, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0778, \"times_seen\": 30.0}, {\"site\": 78, \"mutant\": \"L\", \"escape\": -0.07954712728155854, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0148, \"times_seen\": 128.0}, {\"site\": 78, \"mutant\": \"M\", \"escape\": 0.003830462853186335, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0204, \"times_seen\": 32.0}, {\"site\": 78, \"mutant\": \"N\", \"escape\": -0.505342819456609, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0226, \"times_seen\": 225.0}, {\"site\": 78, \"mutant\": \"P\", \"escape\": 0.3276990397979883, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0158, \"times_seen\": 155.0}, {\"site\": 78, \"mutant\": \"Q\", \"escape\": 0.040703993274625344, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0104, \"times_seen\": 33.0}, {\"site\": 78, \"mutant\": \"R\", \"escape\": -0.09155194834081144, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0699, \"times_seen\": 136.0}, {\"site\": 78, \"mutant\": \"S\", \"escape\": -0.0023573856904635713, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0119, \"times_seen\": 192.0}, {\"site\": 78, \"mutant\": \"T\", \"escape\": 0.07367534528625208, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.0334, \"times_seen\": 127.0}, {\"site\": 78, \"mutant\": \"V\", \"escape\": 0.4323467676081842, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": 0.0193, \"times_seen\": 151.0}, {\"site\": 78, \"mutant\": \"W\", \"escape\": 7.265437885131686e-06, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.1933, \"times_seen\": 40.0}, {\"site\": 78, \"mutant\": \"Y\", \"escape\": 0.014931854551047537, \"epitope\": \"epitope 1\", \"reference_site\": \"80\", \"functional effect\": -0.079, \"times_seen\": 196.0}, {\"site\": 79, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 79, \"mutant\": \"-\", \"escape\": -0.046184804239475755, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.0751, \"times_seen\": 11.0}, {\"site\": 79, \"mutant\": \"D\", \"escape\": 0.07843108809454212, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.1318, \"times_seen\": 47.0}, {\"site\": 79, \"mutant\": \"G\", \"escape\": -0.03784597702076538, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -1.455, \"times_seen\": 1.0}, {\"site\": 79, \"mutant\": \"I\", \"escape\": -0.003767878590283631, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -1.0138, \"times_seen\": 1.0}, {\"site\": 79, \"mutant\": \"K\", \"escape\": 0.04844790748109158, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.2249, \"times_seen\": 29.0}, {\"site\": 79, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 79, \"mutant\": \"Q\", \"escape\": -0.004075451244627537, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": 0.1303, \"times_seen\": 15.0}, {\"site\": 79, \"mutant\": \"S\", \"escape\": -0.04095061643666659, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 79, \"mutant\": \"T\", \"escape\": -0.02523557109702354, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.0202, \"times_seen\": 51.0}, {\"site\": 79, \"mutant\": \"Y\", \"escape\": 0.11601129502810227, \"epitope\": \"epitope 1\", \"reference_site\": \"81\", \"functional effect\": -0.0555, \"times_seen\": 17.0}, {\"site\": 80, \"mutant\": \"A\", \"escape\": -0.005637292359844629, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.752, \"times_seen\": 2.0}, {\"site\": 80, \"mutant\": \"H\", \"escape\": -0.19066792458225063, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.0307, \"times_seen\": 60.0}, {\"site\": 80, \"mutant\": \"L\", \"escape\": -0.06036008101961783, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.2553, \"times_seen\": 53.0}, {\"site\": 80, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 80, \"mutant\": \"R\", \"escape\": 0.044301688430758435, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": 0.0107, \"times_seen\": 9.0}, {\"site\": 80, \"mutant\": \"S\", \"escape\": -0.002553808905100931, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.2198, \"times_seen\": 14.0}, {\"site\": 80, \"mutant\": \"T\", \"escape\": -0.06519753064524059, \"epitope\": \"epitope 1\", \"reference_site\": \"82\", \"functional effect\": -0.1073, \"times_seen\": 16.0}, {\"site\": 81, \"mutant\": \"A\", \"escape\": -0.02289040245473668, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.0657, \"times_seen\": 15.0}, {\"site\": 81, \"mutant\": \"C\", \"escape\": -0.0278930368060073, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.4, \"times_seen\": 12.0}, {\"site\": 81, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.1781, \"times_seen\": null}, {\"site\": 81, \"mutant\": \"F\", \"escape\": 0.00602329644721641, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.1143, \"times_seen\": 33.0}, {\"site\": 81, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 81, \"mutant\": \"I\", \"escape\": 0.2263482568648815, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.14, \"times_seen\": 34.0}, {\"site\": 81, \"mutant\": \"L\", \"escape\": -1.9424275588745021, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.051, \"times_seen\": 33.0}, {\"site\": 81, \"mutant\": \"M\", \"escape\": 0.009123200419817389, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.0638, \"times_seen\": 5.0}, {\"site\": 81, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -3.251, \"times_seen\": null}, {\"site\": 81, \"mutant\": \"T\", \"escape\": -0.05496293771619365, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": -0.0464, \"times_seen\": 13.0}, {\"site\": 81, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"83\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 82, \"mutant\": \"I\", \"escape\": 0.044743282101003604, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": 0.2581, \"times_seen\": 24.0}, {\"site\": 82, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 82, \"mutant\": \"M\", \"escape\": 0.008734748683685432, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.0035, \"times_seen\": 10.0}, {\"site\": 82, \"mutant\": \"P\", \"escape\": -0.05144614040550347, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.9968, \"times_seen\": 19.0}, {\"site\": 82, \"mutant\": \"Q\", \"escape\": -0.021344183234751988, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.0575, \"times_seen\": 27.0}, {\"site\": 82, \"mutant\": \"V\", \"escape\": -0.08098896849484698, \"epitope\": \"epitope 1\", \"reference_site\": \"84\", \"functional effect\": -0.1762, \"times_seen\": 21.0}, {\"site\": 83, \"mutant\": \"-\", \"escape\": 0.04470359785551281, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.4579, \"times_seen\": 22.0}, {\"site\": 83, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.4456, \"times_seen\": null}, {\"site\": 83, \"mutant\": \"L\", \"escape\": -0.02641208907938567, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.164, \"times_seen\": 98.0}, {\"site\": 83, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 83, \"mutant\": \"Q\", \"escape\": -0.03271725521100559, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.1271, \"times_seen\": 19.0}, {\"site\": 83, \"mutant\": \"R\", \"escape\": -0.004635758911361685, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.2285, \"times_seen\": 2.0}, {\"site\": 83, \"mutant\": \"S\", \"escape\": 0.08644431429132773, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": 0.0082, \"times_seen\": 51.0}, {\"site\": 83, \"mutant\": \"T\", \"escape\": 0.27296695878786836, \"epitope\": \"epitope 1\", \"reference_site\": \"85\", \"functional effect\": -0.0122, \"times_seen\": 22.0}, {\"site\": 84, \"mutant\": \"-\", \"escape\": -0.0016901332104326539, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -3.0402, \"times_seen\": 1.0}, {\"site\": 84, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 84, \"mutant\": \"I\", \"escape\": -0.0234576375076903, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.6218, \"times_seen\": 21.0}, {\"site\": 84, \"mutant\": \"L\", \"escape\": 0.05903089781944803, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.7148, \"times_seen\": 39.0}, {\"site\": 84, \"mutant\": \"S\", \"escape\": 0.018386838773289383, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -2.3934, \"times_seen\": 2.0}, {\"site\": 84, \"mutant\": \"V\", \"escape\": 0.022025810759304838, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.7449, \"times_seen\": 7.0}, {\"site\": 84, \"mutant\": \"Y\", \"escape\": -0.014409868226377822, \"epitope\": \"epitope 1\", \"reference_site\": \"86\", \"functional effect\": -0.0766, \"times_seen\": 22.0}, {\"site\": 85, \"mutant\": \"-\", \"escape\": -0.020556996038911517, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -2.4263, \"times_seen\": 6.0}, {\"site\": 85, \"mutant\": \"C\", \"escape\": -0.03478649797176896, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.136, \"times_seen\": 9.0}, {\"site\": 85, \"mutant\": \"D\", \"escape\": 0.014971818355322002, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.1528, \"times_seen\": 24.0}, {\"site\": 85, \"mutant\": \"H\", \"escape\": 0.011816734324207738, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.0457, \"times_seen\": 23.0}, {\"site\": 85, \"mutant\": \"I\", \"escape\": 0.011420567338582396, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.0667, \"times_seen\": 19.0}, {\"site\": 85, \"mutant\": \"K\", \"escape\": 0.325217198035598, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.0785, \"times_seen\": 42.0}, {\"site\": 85, \"mutant\": \"M\", \"escape\": -1.75556724627882, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.2563, \"times_seen\": 13.0}, {\"site\": 85, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 85, \"mutant\": \"S\", \"escape\": -0.020596811684809063, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.0829, \"times_seen\": 48.0}, {\"site\": 85, \"mutant\": \"T\", \"escape\": 0.053650146104808304, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": -0.0264, \"times_seen\": 17.0}, {\"site\": 85, \"mutant\": \"Y\", \"escape\": -0.6638405425529259, \"epitope\": \"epitope 1\", \"reference_site\": \"87\", \"functional effect\": 0.1479, \"times_seen\": 24.0}, {\"site\": 86, \"mutant\": \"-\", \"escape\": 0.0626114767252063, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -2.9525, \"times_seen\": 4.0}, {\"site\": 86, \"mutant\": \"A\", \"escape\": -0.005714500865363759, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.1467, \"times_seen\": 17.0}, {\"site\": 86, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 86, \"mutant\": \"E\", \"escape\": -1.295774314141962, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": 0.0335, \"times_seen\": 81.0}, {\"site\": 86, \"mutant\": \"G\", \"escape\": -0.019631314029793085, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": 0.2801, \"times_seen\": 20.0}, {\"site\": 86, \"mutant\": \"H\", \"escape\": -0.04521568916260473, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.1553, \"times_seen\": 54.0}, {\"site\": 86, \"mutant\": \"L\", \"escape\": 0.0031159655347099027, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.1074, \"times_seen\": 13.0}, {\"site\": 86, \"mutant\": \"N\", \"escape\": -0.09368894227204301, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.2114, \"times_seen\": 73.0}, {\"site\": 86, \"mutant\": \"Y\", \"escape\": 0.011172501386142768, \"epitope\": \"epitope 1\", \"reference_site\": \"88\", \"functional effect\": -0.4421, \"times_seen\": 58.0}, {\"site\": 87, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"-\", \"escape\": 0.008574563669910103, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.9064, \"times_seen\": 4.0}, {\"site\": 87, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -1.9226, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.3548, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"M\", \"escape\": -0.021223143305848336, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.258, \"times_seen\": 7.0}, {\"site\": 87, \"mutant\": \"R\", \"escape\": -0.00041579143023439736, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.881, \"times_seen\": 1.0}, {\"site\": 87, \"mutant\": \"V\", \"escape\": 0.022058258559110387, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -1.9767, \"times_seen\": 8.0}, {\"site\": 87, \"mutant\": \"W\", \"escape\": -0.00912842624173647, \"epitope\": \"epitope 1\", \"reference_site\": \"89\", \"functional effect\": -2.8347, \"times_seen\": 3.0}, {\"site\": 88, \"mutant\": \"-\", \"escape\": -0.006058599498745653, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -2.6703, \"times_seen\": 2.0}, {\"site\": 88, \"mutant\": \"A\", \"escape\": -0.008537055493284783, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.0255, \"times_seen\": 15.0}, {\"site\": 88, \"mutant\": \"C\", \"escape\": -0.010110092885150591, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.2364, \"times_seen\": 12.0}, {\"site\": 88, \"mutant\": \"D\", \"escape\": -0.007119680585634977, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -3.1398, \"times_seen\": 2.0}, {\"site\": 88, \"mutant\": \"F\", \"escape\": 0.008899398999854842, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.4407, \"times_seen\": 76.0}, {\"site\": 88, \"mutant\": \"I\", \"escape\": -0.026400547318382123, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.0555, \"times_seen\": 101.0}, {\"site\": 88, \"mutant\": \"L\", \"escape\": 0.017121831140725702, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.183, \"times_seen\": 33.0}, {\"site\": 88, \"mutant\": \"M\", \"escape\": 0.012567384020683027, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.0793, \"times_seen\": 12.0}, {\"site\": 88, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -3.002, \"times_seen\": null}, {\"site\": 88, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": -0.2691, \"times_seen\": null}, {\"site\": 88, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"90\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.5509, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -3.0806, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"D\", \"escape\": -0.0033528770138621503, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.9475, \"times_seen\": 2.0}, {\"site\": 89, \"mutant\": \"F\", \"escape\": -0.037359009339138556, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -0.2771, \"times_seen\": 20.0}, {\"site\": 89, \"mutant\": \"H\", \"escape\": -0.0017176631530390898, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -3.0231, \"times_seen\": 5.0}, {\"site\": 89, \"mutant\": \"L\", \"escape\": -0.006874146276469354, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.8708, \"times_seen\": 1.0}, {\"site\": 89, \"mutant\": \"T\", \"escape\": 0.012965382514578787, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -3.114, \"times_seen\": 2.0}, {\"site\": 89, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"91\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 90, \"mutant\": \"C\", \"escape\": -0.013922975281330793, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.3614, \"times_seen\": 17.0}, {\"site\": 90, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 90, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -1.1825, \"times_seen\": null}, {\"site\": 90, \"mutant\": \"I\", \"escape\": 0.017212244976712806, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.1833, \"times_seen\": 15.0}, {\"site\": 90, \"mutant\": \"L\", \"escape\": -0.04614475740498461, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.3369, \"times_seen\": 24.0}, {\"site\": 90, \"mutant\": \"S\", \"escape\": -0.019090035658617194, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.6505, \"times_seen\": 6.0}, {\"site\": 90, \"mutant\": \"V\", \"escape\": 0.0019196266714409374, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.2806, \"times_seen\": 12.0}, {\"site\": 90, \"mutant\": \"Y\", \"escape\": -0.020879199922661986, \"epitope\": \"epitope 1\", \"reference_site\": \"92\", \"functional effect\": -0.0885, \"times_seen\": 10.0}, {\"site\": 91, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 91, \"mutant\": \"C\", \"escape\": -0.0007733797137624236, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.5236, \"times_seen\": 17.0}, {\"site\": 91, \"mutant\": \"D\", \"escape\": -0.0016282463264000637, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -2.5734, \"times_seen\": 1.0}, {\"site\": 91, \"mutant\": \"I\", \"escape\": 0.057585995714126925, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -2.5408, \"times_seen\": 5.0}, {\"site\": 91, \"mutant\": \"L\", \"escape\": -0.026030465794424605, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.2054, \"times_seen\": 10.0}, {\"site\": 91, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -3.2479, \"times_seen\": null}, {\"site\": 91, \"mutant\": \"P\", \"escape\": -0.006783244643180706, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -2.4163, \"times_seen\": 2.0}, {\"site\": 91, \"mutant\": \"S\", \"escape\": -0.04490849306226677, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.2226, \"times_seen\": 67.0}, {\"site\": 91, \"mutant\": \"T\", \"escape\": -0.03649252952574377, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.5812, \"times_seen\": 29.0}, {\"site\": 91, \"mutant\": \"V\", \"escape\": -0.07143410851479255, \"epitope\": \"epitope 1\", \"reference_site\": \"93\", \"functional effect\": -0.9631, \"times_seen\": 56.0}, {\"site\": 92, \"mutant\": \"A\", \"escape\": -0.501152728712722, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.0349, \"times_seen\": 73.0}, {\"site\": 92, \"mutant\": \"C\", \"escape\": -0.01601303798301695, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.2343, \"times_seen\": 26.0}, {\"site\": 92, \"mutant\": \"F\", \"escape\": 0.004283839515238002, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.3526, \"times_seen\": 48.0}, {\"site\": 92, \"mutant\": \"G\", \"escape\": 0.0032114173484012677, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": 0.1911, \"times_seen\": 21.0}, {\"site\": 92, \"mutant\": \"I\", \"escape\": -0.006410775155883723, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.2027, \"times_seen\": 6.0}, {\"site\": 92, \"mutant\": \"L\", \"escape\": 0.07449049260221892, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.3224, \"times_seen\": 13.0}, {\"site\": 92, \"mutant\": \"N\", \"escape\": 0.0014255822878056045, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.155, \"times_seen\": 42.0}, {\"site\": 92, \"mutant\": \"P\", \"escape\": -0.013212620621167194, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -2.3846, \"times_seen\": 6.0}, {\"site\": 92, \"mutant\": \"R\", \"escape\": -0.02234044302798742, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.2821, \"times_seen\": 6.0}, {\"site\": 92, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 92, \"mutant\": \"T\", \"escape\": -0.009120542200338396, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.0316, \"times_seen\": 29.0}, {\"site\": 92, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 92, \"mutant\": \"Y\", \"escape\": -0.012555423976791841, \"epitope\": \"epitope 1\", \"reference_site\": \"94\", \"functional effect\": -0.5048, \"times_seen\": 16.0}, {\"site\": 93, \"mutant\": \"*\", \"escape\": -0.007645459181818343, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -3.0486, \"times_seen\": 3.0}, {\"site\": 93, \"mutant\": \"A\", \"escape\": 0.348280991536501, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1267, \"times_seen\": 107.0}, {\"site\": 93, \"mutant\": \"C\", \"escape\": -0.06269380689353661, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1959, \"times_seen\": 45.0}, {\"site\": 93, \"mutant\": \"D\", \"escape\": 0.36209504777007506, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 93, \"mutant\": \"E\", \"escape\": -1.333973776590861, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.4635, \"times_seen\": 27.0}, {\"site\": 93, \"mutant\": \"F\", \"escape\": 0.029611647820243517, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.224, \"times_seen\": 76.0}, {\"site\": 93, \"mutant\": \"G\", \"escape\": -0.02882642858212215, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.5816, \"times_seen\": 36.0}, {\"site\": 93, \"mutant\": \"H\", \"escape\": -0.047886227801294486, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.2237, \"times_seen\": 50.0}, {\"site\": 93, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 93, \"mutant\": \"K\", \"escape\": -0.013409404072388225, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1445, \"times_seen\": 30.0}, {\"site\": 93, \"mutant\": \"L\", \"escape\": -0.048073104584681045, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.0639, \"times_seen\": 116.0}, {\"site\": 93, \"mutant\": \"M\", \"escape\": -0.008039061086288124, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.0785, \"times_seen\": 50.0}, {\"site\": 93, \"mutant\": \"N\", \"escape\": 0.559785984248735, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.3256, \"times_seen\": 48.0}, {\"site\": 93, \"mutant\": \"P\", \"escape\": -0.394501997479506, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.8856, \"times_seen\": 65.0}, {\"site\": 93, \"mutant\": \"Q\", \"escape\": 0.07473787159631556, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.2541, \"times_seen\": 19.0}, {\"site\": 93, \"mutant\": \"R\", \"escape\": 0.060807881866456116, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1713, \"times_seen\": 73.0}, {\"site\": 93, \"mutant\": \"S\", \"escape\": -0.10539881164922886, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.112, \"times_seen\": 173.0}, {\"site\": 93, \"mutant\": \"T\", \"escape\": -0.0022227941695628648, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1663, \"times_seen\": 146.0}, {\"site\": 93, \"mutant\": \"V\", \"escape\": 0.004567070403397333, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": 0.1071, \"times_seen\": 81.0}, {\"site\": 93, \"mutant\": \"W\", \"escape\": 0.04839880780200532, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.1706, \"times_seen\": 20.0}, {\"site\": 93, \"mutant\": \"Y\", \"escape\": 0.007098953700308254, \"epitope\": \"epitope 1\", \"reference_site\": \"95\", \"functional effect\": -0.2847, \"times_seen\": 33.0}, {\"site\": 94, \"mutant\": \"*\", \"escape\": -0.003990763737218472, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -2.3838, \"times_seen\": 1.0}, {\"site\": 94, \"mutant\": \"A\", \"escape\": -0.3925007717175866, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.0316, \"times_seen\": 46.0}, {\"site\": 94, \"mutant\": \"D\", \"escape\": 0.1703293097438454, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.0467, \"times_seen\": 99.0}, {\"site\": 94, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 94, \"mutant\": \"G\", \"escape\": -0.030574611962965646, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.1099, \"times_seen\": 9.0}, {\"site\": 94, \"mutant\": \"K\", \"escape\": -0.07121104075304494, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3729, \"times_seen\": 43.0}, {\"site\": 94, \"mutant\": \"L\", \"escape\": 0.00042670927881713284, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3496, \"times_seen\": 18.0}, {\"site\": 94, \"mutant\": \"P\", \"escape\": -0.024074331484747764, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.5903, \"times_seen\": 11.0}, {\"site\": 94, \"mutant\": \"Q\", \"escape\": 0.006565271474915862, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.0732, \"times_seen\": 58.0}, {\"site\": 94, \"mutant\": \"V\", \"escape\": -0.03645923646012411, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3448, \"times_seen\": 69.0}, {\"site\": 94, \"mutant\": \"Y\", \"escape\": 0.03717599189978562, \"epitope\": \"epitope 1\", \"reference_site\": \"96\", \"functional effect\": -0.3054, \"times_seen\": 13.0}, {\"site\": 95, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 95, \"mutant\": \"E\", \"escape\": -0.04325572619801589, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0891, \"times_seen\": 71.0}, {\"site\": 95, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 95, \"mutant\": \"L\", \"escape\": -0.012119843374592251, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": -0.124, \"times_seen\": 10.0}, {\"site\": 95, \"mutant\": \"M\", \"escape\": 0.3205191943052416, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0141, \"times_seen\": 20.0}, {\"site\": 95, \"mutant\": \"N\", \"escape\": -0.06425895593983512, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0086, \"times_seen\": 76.0}, {\"site\": 95, \"mutant\": \"Q\", \"escape\": 0.01731974630288405, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0609, \"times_seen\": 23.0}, {\"site\": 95, \"mutant\": \"R\", \"escape\": 0.2181139240233604, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.0146, \"times_seen\": 65.0}, {\"site\": 95, \"mutant\": \"T\", \"escape\": 1.8382459851614363, \"epitope\": \"epitope 1\", \"reference_site\": \"97\", \"functional effect\": 0.2037, \"times_seen\": 7.0}, {\"site\": 96, \"mutant\": \"*\", \"escape\": 0.08690285699354892, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -2.5427, \"times_seen\": 6.0}, {\"site\": 96, \"mutant\": \"A\", \"escape\": 0.08635247710542489, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0308, \"times_seen\": 172.0}, {\"site\": 96, \"mutant\": \"C\", \"escape\": -0.08685472625874242, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.1456, \"times_seen\": 77.0}, {\"site\": 96, \"mutant\": \"D\", \"escape\": -0.06949221922419115, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0324, \"times_seen\": 60.0}, {\"site\": 96, \"mutant\": \"E\", \"escape\": -0.029053238624172605, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0439, \"times_seen\": 46.0}, {\"site\": 96, \"mutant\": \"F\", \"escape\": -0.03382037789553157, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.1165, \"times_seen\": 204.0}, {\"site\": 96, \"mutant\": \"G\", \"escape\": -0.11504471131084487, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0492, \"times_seen\": 122.0}, {\"site\": 96, \"mutant\": \"H\", \"escape\": 0.123756991270734, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0515, \"times_seen\": 88.0}, {\"site\": 96, \"mutant\": \"I\", \"escape\": 0.164504282292029, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0559, \"times_seen\": 133.0}, {\"site\": 96, \"mutant\": \"K\", \"escape\": 0.15372354300505328, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0309, \"times_seen\": 59.0}, {\"site\": 96, \"mutant\": \"L\", \"escape\": -0.19036909666010793, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0364, \"times_seen\": 168.0}, {\"site\": 96, \"mutant\": \"M\", \"escape\": -0.39667265781085387, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0211, \"times_seen\": 43.0}, {\"site\": 96, \"mutant\": \"N\", \"escape\": -0.07014312032899973, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.074, \"times_seen\": 150.0}, {\"site\": 96, \"mutant\": \"P\", \"escape\": -0.012146847786097132, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.1268, \"times_seen\": 162.0}, {\"site\": 96, \"mutant\": \"Q\", \"escape\": -0.04998757696504082, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0761, \"times_seen\": 70.0}, {\"site\": 96, \"mutant\": \"R\", \"escape\": 0.317101610951393, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0237, \"times_seen\": 304.0}, {\"site\": 96, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 96, \"mutant\": \"T\", \"escape\": 0.05275800314969066, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0523, \"times_seen\": 182.0}, {\"site\": 96, \"mutant\": \"V\", \"escape\": -0.09040289566308264, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.0558, \"times_seen\": 130.0}, {\"site\": 96, \"mutant\": \"W\", \"escape\": 0.02911730757863448, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.083, \"times_seen\": 60.0}, {\"site\": 96, \"mutant\": \"Y\", \"escape\": -0.033153871894766526, \"epitope\": \"epitope 1\", \"reference_site\": \"98\", \"functional effect\": -0.001, \"times_seen\": 111.0}, {\"site\": 97, \"mutant\": \"D\", \"escape\": -0.11841198141548673, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0318, \"times_seen\": 88.0}, {\"site\": 97, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.6425, \"times_seen\": null}, {\"site\": 97, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.4147, \"times_seen\": null}, {\"site\": 97, \"mutant\": \"I\", \"escape\": -0.0008013120861688612, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.3138, \"times_seen\": 1.0}, {\"site\": 97, \"mutant\": \"K\", \"escape\": -0.2639584106697374, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": 0.0587, \"times_seen\": 54.0}, {\"site\": 97, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 97, \"mutant\": \"S\", \"escape\": 0.04278043124514764, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0383, \"times_seen\": 94.0}, {\"site\": 97, \"mutant\": \"T\", \"escape\": -0.012342542579577589, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0293, \"times_seen\": 39.0}, {\"site\": 97, \"mutant\": \"Y\", \"escape\": 0.08448173789318496, \"epitope\": \"epitope 1\", \"reference_site\": \"99\", \"functional effect\": -0.0632, \"times_seen\": 47.0}, {\"site\": 98, \"mutant\": \"-\", \"escape\": -0.002940230927892494, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.4301, \"times_seen\": 1.0}, {\"site\": 98, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.0746, \"times_seen\": null}, {\"site\": 98, \"mutant\": \"H\", \"escape\": -0.06479534089960075, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0559, \"times_seen\": 57.0}, {\"site\": 98, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 98, \"mutant\": \"K\", \"escape\": 0.012488547597806742, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.1329, \"times_seen\": 25.0}, {\"site\": 98, \"mutant\": \"L\", \"escape\": 0.004387965208676733, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.0736, \"times_seen\": 64.0}, {\"site\": 98, \"mutant\": \"M\", \"escape\": 0.021826399445888805, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.031, \"times_seen\": 28.0}, {\"site\": 98, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 98, \"mutant\": \"R\", \"escape\": 0.0010294016926129077, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.185, \"times_seen\": 23.0}, {\"site\": 98, \"mutant\": \"S\", \"escape\": -0.003874670908753768, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": -0.1495, \"times_seen\": 1.0}, {\"site\": 98, \"mutant\": \"T\", \"escape\": -0.035882748663356646, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0456, \"times_seen\": 125.0}, {\"site\": 98, \"mutant\": \"V\", \"escape\": -0.11113222470596545, \"epitope\": \"epitope 1\", \"reference_site\": \"100\", \"functional effect\": 0.0125, \"times_seen\": 75.0}, {\"site\": 99, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 99, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.1396, \"times_seen\": null}, {\"site\": 99, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 99, \"mutant\": \"L\", \"escape\": 0.0835198992611698, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.0312, \"times_seen\": 14.0}, {\"site\": 99, \"mutant\": \"M\", \"escape\": -0.03320423429989614, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": 0.0773, \"times_seen\": 19.0}, {\"site\": 99, \"mutant\": \"N\", \"escape\": -0.12096979381298087, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.134, \"times_seen\": 38.0}, {\"site\": 99, \"mutant\": \"S\", \"escape\": 0.006672193799468741, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.1162, \"times_seen\": 1.0}, {\"site\": 99, \"mutant\": \"T\", \"escape\": 0.001141122842065677, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.0282, \"times_seen\": 88.0}, {\"site\": 99, \"mutant\": \"V\", \"escape\": 0.35280073908459836, \"epitope\": \"epitope 1\", \"reference_site\": \"101\", \"functional effect\": -0.0332, \"times_seen\": 42.0}, {\"site\": 100, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 100, \"mutant\": \"A\", \"escape\": -0.008984132819635435, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.3679, \"times_seen\": 10.0}, {\"site\": 100, \"mutant\": \"G\", \"escape\": 0.003912868937834737, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0811, \"times_seen\": 72.0}, {\"site\": 100, \"mutant\": \"I\", \"escape\": -0.034400071728124766, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0793, \"times_seen\": 77.0}, {\"site\": 100, \"mutant\": \"K\", \"escape\": 0.30246581322770333, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": -0.0588, \"times_seen\": 85.0}, {\"site\": 100, \"mutant\": \"M\", \"escape\": 0.009974352919036802, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.1373, \"times_seen\": 5.0}, {\"site\": 100, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 100, \"mutant\": \"S\", \"escape\": -0.04782382722035523, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0496, \"times_seen\": 74.0}, {\"site\": 100, \"mutant\": \"T\", \"escape\": 0.00031958811578928863, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": 0.0622, \"times_seen\": 21.0}, {\"site\": 100, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"102\", \"functional effect\": -0.4304, \"times_seen\": null}, {\"site\": 101, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 101, \"mutant\": \"C\", \"escape\": -0.03825779960736029, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.257, \"times_seen\": 28.0}, {\"site\": 101, \"mutant\": \"D\", \"escape\": -0.025597831557033678, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -2.2717, \"times_seen\": 3.0}, {\"site\": 101, \"mutant\": \"F\", \"escape\": 0.16972621890391787, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.2139, \"times_seen\": 21.0}, {\"site\": 101, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 101, \"mutant\": \"R\", \"escape\": -1.1906917567259412, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.7102, \"times_seen\": 11.0}, {\"site\": 101, \"mutant\": \"S\", \"escape\": -0.0712375525549687, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -0.5601, \"times_seen\": 31.0}, {\"site\": 101, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"103\", \"functional effect\": -1.5467, \"times_seen\": null}, {\"site\": 102, \"mutant\": \"*\", \"escape\": 0.0198725389351127, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -2.5166, \"times_seen\": 3.0}, {\"site\": 102, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 102, \"mutant\": \"C\", \"escape\": -0.003722197602944989, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -1.8512, \"times_seen\": 2.0}, {\"site\": 102, \"mutant\": \"F\", \"escape\": -0.08569964802934606, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -0.187, \"times_seen\": 24.0}, {\"site\": 102, \"mutant\": \"G\", \"escape\": -0.0027842028077018316, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -1.3353, \"times_seen\": 9.0}, {\"site\": 102, \"mutant\": \"L\", \"escape\": 0.8687318749058404, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -0.3178, \"times_seen\": 35.0}, {\"site\": 102, \"mutant\": \"R\", \"escape\": -0.0004940779542232765, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -2.3409, \"times_seen\": 5.0}, {\"site\": 102, \"mutant\": \"S\", \"escape\": 0.03269669905089398, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": -1.9068, \"times_seen\": 8.0}, {\"site\": 102, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"104\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 103, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 103, \"mutant\": \"F\", \"escape\": -0.019843159200423063, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.35, \"times_seen\": 23.0}, {\"site\": 103, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 103, \"mutant\": \"L\", \"escape\": -0.123211490240024, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.1699, \"times_seen\": 44.0}, {\"site\": 103, \"mutant\": \"N\", \"escape\": 1.152997763567643, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.5794, \"times_seen\": 5.0}, {\"site\": 103, \"mutant\": \"S\", \"escape\": 0.0019323973536738536, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": 0.1526, \"times_seen\": 1.0}, {\"site\": 103, \"mutant\": \"T\", \"escape\": -0.012128580722987527, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.1673, \"times_seen\": 106.0}, {\"site\": 103, \"mutant\": \"V\", \"escape\": -0.02119416272051688, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.0713, \"times_seen\": 54.0}, {\"site\": 103, \"mutant\": \"Y\", \"escape\": -0.007054063843780428, \"epitope\": \"epitope 1\", \"reference_site\": \"105\", \"functional effect\": -0.1562, \"times_seen\": 27.0}, {\"site\": 104, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 104, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 104, \"mutant\": \"I\", \"escape\": 0.0393341051657055, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -1.1841, \"times_seen\": 28.0}, {\"site\": 104, \"mutant\": \"L\", \"escape\": 0.012370098922806974, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -0.2396, \"times_seen\": 57.0}, {\"site\": 104, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 104, \"mutant\": \"V\", \"escape\": -0.06140610795166887, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -1.1602, \"times_seen\": 22.0}, {\"site\": 104, \"mutant\": \"Y\", \"escape\": 0.28802685492905716, \"epitope\": \"epitope 1\", \"reference_site\": \"106\", \"functional effect\": -0.067, \"times_seen\": 45.0}, {\"site\": 105, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 105, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.1019, \"times_seen\": null}, {\"site\": 105, \"mutant\": \"C\", \"escape\": -0.033925195479669525, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.0577, \"times_seen\": 11.0}, {\"site\": 105, \"mutant\": \"D\", \"escape\": -0.018115008711041578, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.5776, \"times_seen\": 3.0}, {\"site\": 105, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 105, \"mutant\": \"L\", \"escape\": 0.022180866901591333, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -1.6558, \"times_seen\": 9.0}, {\"site\": 105, \"mutant\": \"R\", \"escape\": -0.026062977885293166, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.156, \"times_seen\": 10.0}, {\"site\": 105, \"mutant\": \"S\", \"escape\": -0.022004086860566423, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -1.5646, \"times_seen\": 4.0}, {\"site\": 105, \"mutant\": \"V\", \"escape\": -1.1942579707362968, \"epitope\": \"epitope 1\", \"reference_site\": \"107\", \"functional effect\": -2.9922, \"times_seen\": 5.0}, {\"site\": 106, \"mutant\": \"-\", \"escape\": -0.0031122129786728195, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.7745, \"times_seen\": 7.0}, {\"site\": 106, \"mutant\": \"A\", \"escape\": -0.017972775541511853, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.0697, \"times_seen\": 42.0}, {\"site\": 106, \"mutant\": \"C\", \"escape\": 0.010639417976061258, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.4085, \"times_seen\": 4.0}, {\"site\": 106, \"mutant\": \"D\", \"escape\": -0.0011975299536184708, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -2.001, \"times_seen\": 1.0}, {\"site\": 106, \"mutant\": \"I\", \"escape\": 0.34891491787041906, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.3128, \"times_seen\": 90.0}, {\"site\": 106, \"mutant\": \"L\", \"escape\": -0.0020267768941609216, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": -0.2263, \"times_seen\": 4.0}, {\"site\": 106, \"mutant\": \"N\", \"escape\": -0.09465776158442274, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": 0.3447, \"times_seen\": 47.0}, {\"site\": 106, \"mutant\": \"S\", \"escape\": -0.01571631869768068, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": 0.152, \"times_seen\": 31.0}, {\"site\": 106, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"108\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 107, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 107, \"mutant\": \"A\", \"escape\": 0.22110440152919936, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.0787, \"times_seen\": 44.0}, {\"site\": 107, \"mutant\": \"I\", \"escape\": -1.3771029835696673, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -1.0708, \"times_seen\": 45.0}, {\"site\": 107, \"mutant\": \"K\", \"escape\": -0.03981822856588157, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.2012, \"times_seen\": 14.0}, {\"site\": 107, \"mutant\": \"L\", \"escape\": -0.014832317870399372, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.2797, \"times_seen\": 2.0}, {\"site\": 107, \"mutant\": \"N\", \"escape\": -1.7299155305520317, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.137, \"times_seen\": 39.0}, {\"site\": 107, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -3.0375, \"times_seen\": null}, {\"site\": 107, \"mutant\": \"R\", \"escape\": -0.01825869151859219, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": -0.5204, \"times_seen\": 7.0}, {\"site\": 107, \"mutant\": \"S\", \"escape\": -0.03473685899516939, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": 0.1497, \"times_seen\": 8.0}, {\"site\": 107, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"109\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"F\", \"escape\": 0.0007663228297702461, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": 0.1351, \"times_seen\": 8.0}, {\"site\": 108, \"mutant\": \"I\", \"escape\": -0.01661971508687579, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.373, \"times_seen\": 17.0}, {\"site\": 108, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"M\", \"escape\": -1.2504961365203757, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.0224, \"times_seen\": 17.0}, {\"site\": 108, \"mutant\": \"P\", \"escape\": -0.036879712812358, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -1.5686, \"times_seen\": 8.0}, {\"site\": 108, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -1.0578, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"V\", \"escape\": -0.7982160444789181, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.6082, \"times_seen\": 61.0}, {\"site\": 108, \"mutant\": \"Y\", \"escape\": -0.03118518004107116, \"epitope\": \"epitope 1\", \"reference_site\": \"110\", \"functional effect\": -0.4187, \"times_seen\": 13.0}, {\"site\": 109, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 109, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 109, \"mutant\": \"E\", \"escape\": 0.03236172129145244, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.2564, \"times_seen\": 38.0}, {\"site\": 109, \"mutant\": \"G\", \"escape\": -0.16876598519266306, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.2263, \"times_seen\": 77.0}, {\"site\": 109, \"mutant\": \"H\", \"escape\": -0.15009718576910144, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.2835, \"times_seen\": 160.0}, {\"site\": 109, \"mutant\": \"I\", \"escape\": 0.02481828077083203, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -1.4678, \"times_seen\": 13.0}, {\"site\": 109, \"mutant\": \"N\", \"escape\": -0.0463494097280378, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.0352, \"times_seen\": 122.0}, {\"site\": 109, \"mutant\": \"P\", \"escape\": 0.015011997899100944, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -1.9815, \"times_seen\": 12.0}, {\"site\": 109, \"mutant\": \"R\", \"escape\": 0.11926404121973493, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.1555, \"times_seen\": 16.0}, {\"site\": 109, \"mutant\": \"Y\", \"escape\": -0.002022298436406786, \"epitope\": \"epitope 1\", \"reference_site\": \"111\", \"functional effect\": -0.9627, \"times_seen\": 4.0}, {\"site\": 110, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 110, \"mutant\": \"A\", \"escape\": -0.1804795866299792, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.1061, \"times_seen\": 30.0}, {\"site\": 110, \"mutant\": \"F\", \"escape\": 0.4942173030003376, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0792, \"times_seen\": 51.0}, {\"site\": 110, \"mutant\": \"G\", \"escape\": -0.008123317140827922, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.1917, \"times_seen\": 2.0}, {\"site\": 110, \"mutant\": \"H\", \"escape\": -0.006141127141295031, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 110, \"mutant\": \"I\", \"escape\": -0.014423474981469533, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.2182, \"times_seen\": 7.0}, {\"site\": 110, \"mutant\": \"K\", \"escape\": 0.019245987870577276, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0034, \"times_seen\": 23.0}, {\"site\": 110, \"mutant\": \"L\", \"escape\": -2.421471833371257, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.126, \"times_seen\": 61.0}, {\"site\": 110, \"mutant\": \"M\", \"escape\": -0.05652819798694868, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0271, \"times_seen\": 41.0}, {\"site\": 110, \"mutant\": \"N\", \"escape\": -0.015090982336366571, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0242, \"times_seen\": 59.0}, {\"site\": 110, \"mutant\": \"P\", \"escape\": -0.008014252972263184, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.2199, \"times_seen\": 113.0}, {\"site\": 110, \"mutant\": \"Q\", \"escape\": -0.05112140947782289, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0148, \"times_seen\": 20.0}, {\"site\": 110, \"mutant\": \"R\", \"escape\": -0.05541350480088811, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.0657, \"times_seen\": 25.0}, {\"site\": 110, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 110, \"mutant\": \"T\", \"escape\": -0.06998399919569331, \"epitope\": \"epitope 1\", \"reference_site\": \"112\", \"functional effect\": -0.069, \"times_seen\": 39.0}, {\"site\": 111, \"mutant\": \"E\", \"escape\": -0.03580986688094166, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.4226, \"times_seen\": 39.0}, {\"site\": 111, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 111, \"mutant\": \"M\", \"escape\": 0.0059692071962344365, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.2109, \"times_seen\": 30.0}, {\"site\": 111, \"mutant\": \"N\", \"escape\": -0.04580250980837913, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.2066, \"times_seen\": 55.0}, {\"site\": 111, \"mutant\": \"P\", \"escape\": 0.010826441968748582, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.0809, \"times_seen\": 8.0}, {\"site\": 111, \"mutant\": \"Q\", \"escape\": 0.03652002660634005, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.3784, \"times_seen\": 24.0}, {\"site\": 111, \"mutant\": \"R\", \"escape\": 0.05186501972216062, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": 0.0556, \"times_seen\": 60.0}, {\"site\": 111, \"mutant\": \"S\", \"escape\": -0.029183127040277732, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": -0.0779, \"times_seen\": 12.0}, {\"site\": 111, \"mutant\": \"T\", \"escape\": 0.00521438800250303, \"epitope\": \"epitope 1\", \"reference_site\": \"113\", \"functional effect\": 0.0329, \"times_seen\": 8.0}, {\"site\": 112, \"mutant\": \"A\", \"escape\": 0.05785347867410469, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -0.3857, \"times_seen\": 8.0}, {\"site\": 112, \"mutant\": \"I\", \"escape\": 0.0347959499607821, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -2.572, \"times_seen\": 4.0}, {\"site\": 112, \"mutant\": \"N\", \"escape\": -0.006230937548469328, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -1.8954, \"times_seen\": 2.0}, {\"site\": 112, \"mutant\": \"P\", \"escape\": -0.009017144036754883, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": -1.9387, \"times_seen\": 4.0}, {\"site\": 112, \"mutant\": \"S\", \"escape\": 0.013283501488866882, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": 0.1233, \"times_seen\": 11.0}, {\"site\": 112, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"114\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 113, \"mutant\": \"*\", \"escape\": -0.00538313876265497, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -2.592, \"times_seen\": 2.0}, {\"site\": 113, \"mutant\": \"H\", \"escape\": 0.02330239059639686, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 113, \"mutant\": \"K\", \"escape\": 0.039999909135522344, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -1.5896, \"times_seen\": 12.0}, {\"site\": 113, \"mutant\": \"L\", \"escape\": 0.015818814491834525, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -0.535, \"times_seen\": 10.0}, {\"site\": 113, \"mutant\": \"P\", \"escape\": -0.006449712589722635, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -0.6093, \"times_seen\": 18.0}, {\"site\": 113, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 113, \"mutant\": \"R\", \"escape\": 0.008802455077556625, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -1.4123, \"times_seen\": 17.0}, {\"site\": 113, \"mutant\": \"S\", \"escape\": 0.010957164905697621, \"epitope\": \"epitope 1\", \"reference_site\": \"115\", \"functional effect\": -0.7012, \"times_seen\": 3.0}, {\"site\": 114, \"mutant\": \"D\", \"escape\": 0.014529843822145769, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 114, \"mutant\": \"F\", \"escape\": -0.0024247075927329225, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.1498, \"times_seen\": 1.0}, {\"site\": 114, \"mutant\": \"K\", \"escape\": 0.007571337101996435, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.2258, \"times_seen\": 2.0}, {\"site\": 114, \"mutant\": \"P\", \"escape\": -0.0028401534927799165, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -3.132, \"times_seen\": 1.0}, {\"site\": 114, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 114, \"mutant\": \"Y\", \"escape\": 0.016339085410019483, \"epitope\": \"epitope 1\", \"reference_site\": \"116\", \"functional effect\": -2.842, \"times_seen\": 2.0}, {\"site\": 115, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -3.2758, \"times_seen\": null}, {\"site\": 115, \"mutant\": \"I\", \"escape\": 0.013720013753062263, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -0.4963, \"times_seen\": 9.0}, {\"site\": 115, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 115, \"mutant\": \"M\", \"escape\": 0.0027420368627890054, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": 0.0261, \"times_seen\": 9.0}, {\"site\": 115, \"mutant\": \"P\", \"escape\": -0.0052387166115527, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 115, \"mutant\": \"R\", \"escape\": 0.0206623436190452, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -2.7012, \"times_seen\": 2.0}, {\"site\": 115, \"mutant\": \"V\", \"escape\": 0.00034459065152541986, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 115, \"mutant\": \"W\", \"escape\": 0.01083492478162529, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -1.1639, \"times_seen\": 5.0}, {\"site\": 115, \"mutant\": \"Y\", \"escape\": -0.00949822005300368, \"epitope\": \"epitope 1\", \"reference_site\": \"117\", \"functional effect\": -1.6211, \"times_seen\": 4.0}, {\"site\": 116, \"mutant\": \"F\", \"escape\": 0.04349346286189117, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.2045, \"times_seen\": 40.0}, {\"site\": 116, \"mutant\": \"I\", \"escape\": -0.2423913494610689, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.0168, \"times_seen\": 75.0}, {\"site\": 116, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 116, \"mutant\": \"M\", \"escape\": -0.044621656569657574, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.0479, \"times_seen\": 32.0}, {\"site\": 116, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -2.9821, \"times_seen\": null}, {\"site\": 116, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.8778, \"times_seen\": null}, {\"site\": 116, \"mutant\": \"V\", \"escape\": 1.0326998808678594, \"epitope\": \"epitope 1\", \"reference_site\": \"118\", \"functional effect\": -0.0866, \"times_seen\": 12.0}, {\"site\": 117, \"mutant\": \"-\", \"escape\": -0.006794440969177411, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -2.9694, \"times_seen\": 2.0}, {\"site\": 117, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -1.067, \"times_seen\": null}, {\"site\": 117, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 117, \"mutant\": \"L\", \"escape\": -0.016779588962989055, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -0.0081, \"times_seen\": 16.0}, {\"site\": 117, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -0.835, \"times_seen\": null}, {\"site\": 117, \"mutant\": \"T\", \"escape\": -0.005494495197716029, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -1.8059, \"times_seen\": 1.0}, {\"site\": 117, \"mutant\": \"V\", \"escape\": -0.14954875171673185, \"epitope\": \"epitope 1\", \"reference_site\": \"119\", \"functional effect\": -0.2743, \"times_seen\": 33.0}, {\"site\": 118, \"mutant\": \"-\", \"escape\": -0.0007988639938299368, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -2.935, \"times_seen\": 1.0}, {\"site\": 118, \"mutant\": \"A\", \"escape\": 0.32714207165807374, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.2152, \"times_seen\": 10.0}, {\"site\": 118, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.481, \"times_seen\": null}, {\"site\": 118, \"mutant\": \"F\", \"escape\": 0.16236172089132592, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0109, \"times_seen\": 45.0}, {\"site\": 118, \"mutant\": \"I\", \"escape\": -0.10157616088520147, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0259, \"times_seen\": 63.0}, {\"site\": 118, \"mutant\": \"L\", \"escape\": 0.01542664664936966, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0043, \"times_seen\": 28.0}, {\"site\": 118, \"mutant\": \"M\", \"escape\": 0.0006519204066915417, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": -0.0183, \"times_seen\": 7.0}, {\"site\": 118, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"120\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 119, \"mutant\": \"-\", \"escape\": 0.0004548856328731573, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -1.5307, \"times_seen\": 3.0}, {\"site\": 119, \"mutant\": \"D\", \"escape\": 0.0071003891917082, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": 0.0972, \"times_seen\": 10.0}, {\"site\": 119, \"mutant\": \"I\", \"escape\": -0.015126893869776052, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.5188, \"times_seen\": 9.0}, {\"site\": 119, \"mutant\": \"K\", \"escape\": -0.2011602848916396, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.6765, \"times_seen\": 19.0}, {\"site\": 119, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 119, \"mutant\": \"S\", \"escape\": -0.030392021948240845, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.1782, \"times_seen\": 49.0}, {\"site\": 119, \"mutant\": \"T\", \"escape\": 1.0982759630410468, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -0.2585, \"times_seen\": 15.0}, {\"site\": 119, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"121\", \"functional effect\": -2.8939, \"times_seen\": null}, {\"site\": 120, \"mutant\": \"-\", \"escape\": -0.00016815451031739297, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -2.2739, \"times_seen\": 6.0}, {\"site\": 120, \"mutant\": \"D\", \"escape\": -0.014866736588913056, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.1638, \"times_seen\": 23.0}, {\"site\": 120, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": 0.3319, \"times_seen\": null}, {\"site\": 120, \"mutant\": \"K\", \"escape\": -0.028894683831541076, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.2587, \"times_seen\": 15.0}, {\"site\": 120, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 120, \"mutant\": \"S\", \"escape\": 0.002372185500403278, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.2652, \"times_seen\": 16.0}, {\"site\": 120, \"mutant\": \"T\", \"escape\": -0.00931345560416768, \"epitope\": \"epitope 1\", \"reference_site\": \"122\", \"functional effect\": -0.1114, \"times_seen\": 9.0}, {\"site\": 121, \"mutant\": \"-\", \"escape\": -0.018028830525286286, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -2.2622, \"times_seen\": 1.0}, {\"site\": 121, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 121, \"mutant\": \"D\", \"escape\": -0.0688017571183872, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.0998, \"times_seen\": 19.0}, {\"site\": 121, \"mutant\": \"E\", \"escape\": -0.005886535103384906, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.2161, \"times_seen\": 1.0}, {\"site\": 121, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -1.6932, \"times_seen\": null}, {\"site\": 121, \"mutant\": \"L\", \"escape\": -0.004996776137557659, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.112, \"times_seen\": 3.0}, {\"site\": 121, \"mutant\": \"P\", \"escape\": -0.006882439978030494, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.0756, \"times_seen\": 1.0}, {\"site\": 121, \"mutant\": \"S\", \"escape\": -0.8975866388276597, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": 0.0374, \"times_seen\": 30.0}, {\"site\": 121, \"mutant\": \"T\", \"escape\": -0.05709374979690384, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.2843, \"times_seen\": 47.0}, {\"site\": 121, \"mutant\": \"V\", \"escape\": -0.010396935624628938, \"epitope\": \"epitope 1\", \"reference_site\": \"123\", \"functional effect\": -0.024, \"times_seen\": 84.0}, {\"site\": 122, \"mutant\": \"-\", \"escape\": 0.05987408003176344, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -1.2814, \"times_seen\": 6.0}, {\"site\": 122, \"mutant\": \"A\", \"escape\": -0.01113445860917026, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.1718, \"times_seen\": 7.0}, {\"site\": 122, \"mutant\": \"I\", \"escape\": -0.045513399854096574, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.3737, \"times_seen\": 54.0}, {\"site\": 122, \"mutant\": \"L\", \"escape\": 0.007089697267619716, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.3962, \"times_seen\": 10.0}, {\"site\": 122, \"mutant\": \"N\", \"escape\": 0.00043169226686849905, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.439, \"times_seen\": 11.0}, {\"site\": 122, \"mutant\": \"S\", \"escape\": -0.004109565862289508, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": -0.0765, \"times_seen\": 14.0}, {\"site\": 122, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"124\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 123, \"mutant\": \"-\", \"escape\": 0.005755943324400323, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -2.1196, \"times_seen\": 6.0}, {\"site\": 123, \"mutant\": \"D\", \"escape\": -0.009072372032154455, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.0348, \"times_seen\": 4.0}, {\"site\": 123, \"mutant\": \"G\", \"escape\": 0.0009731541284364698, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.0677, \"times_seen\": 1.0}, {\"site\": 123, \"mutant\": \"H\", \"escape\": -0.02173087023249021, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.1177, \"times_seen\": 6.0}, {\"site\": 123, \"mutant\": \"I\", \"escape\": 0.001949528564450599, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -1.3304, \"times_seen\": 1.0}, {\"site\": 123, \"mutant\": \"K\", \"escape\": -0.005309050210774789, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.0595, \"times_seen\": 6.0}, {\"site\": 123, \"mutant\": \"M\", \"escape\": -0.012027395858560322, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.0223, \"times_seen\": 8.0}, {\"site\": 123, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 123, \"mutant\": \"S\", \"escape\": 0.36450805522864455, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.1075, \"times_seen\": 15.0}, {\"site\": 123, \"mutant\": \"T\", \"escape\": 0.013391829056124592, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": -0.1681, \"times_seen\": 11.0}, {\"site\": 123, \"mutant\": \"Y\", \"escape\": -0.00022289321074287914, \"epitope\": \"epitope 1\", \"reference_site\": \"125\", \"functional effect\": 0.3921, \"times_seen\": 1.0}, {\"site\": 124, \"mutant\": \"-\", \"escape\": -0.016813565511905545, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 124, \"mutant\": \"A\", \"escape\": 0.0037114172905990984, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.0382, \"times_seen\": 18.0}, {\"site\": 124, \"mutant\": \"E\", \"escape\": -0.00447437860461057, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.1827, \"times_seen\": 1.0}, {\"site\": 124, \"mutant\": \"F\", \"escape\": -0.7211508793614013, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.2101, \"times_seen\": 61.0}, {\"site\": 124, \"mutant\": \"G\", \"escape\": -0.005057466009795861, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.5421, \"times_seen\": 1.0}, {\"site\": 124, \"mutant\": \"I\", \"escape\": -0.0323155695826042, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.219, \"times_seen\": 27.0}, {\"site\": 124, \"mutant\": \"L\", \"escape\": 0.05376624681233894, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.3493, \"times_seen\": 32.0}, {\"site\": 124, \"mutant\": \"M\", \"escape\": -0.03666345454044582, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": -0.0396, \"times_seen\": 13.0}, {\"site\": 124, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"126\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 125, \"mutant\": \"A\", \"escape\": 0.039662016132572524, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.4349, \"times_seen\": 11.0}, {\"site\": 125, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.0781, \"times_seen\": null}, {\"site\": 125, \"mutant\": \"F\", \"escape\": -0.019911493774927975, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.4226, \"times_seen\": 7.0}, {\"site\": 125, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": 0.2259, \"times_seen\": null}, {\"site\": 125, \"mutant\": \"L\", \"escape\": 0.025363209098773785, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.106, \"times_seen\": 35.0}, {\"site\": 125, \"mutant\": \"M\", \"escape\": 0.01057015530392818, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": -0.2638, \"times_seen\": 12.0}, {\"site\": 125, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"127\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"-\", \"escape\": -0.005452419695911262, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -2.3119, \"times_seen\": 2.0}, {\"site\": 126, \"mutant\": \"F\", \"escape\": 0.020974837236392485, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.2409, \"times_seen\": 12.0}, {\"site\": 126, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"L\", \"escape\": -0.025012253159439963, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.4791, \"times_seen\": 18.0}, {\"site\": 126, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": 0.9989, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -1.4896, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -1.743, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.388, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"T\", \"escape\": -0.007570916161429095, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": -0.3778, \"times_seen\": 3.0}, {\"site\": 126, \"mutant\": \"V\", \"escape\": -0.019626560337161526, \"epitope\": \"epitope 1\", \"reference_site\": \"128\", \"functional effect\": 0.0844, \"times_seen\": 32.0}, {\"site\": 127, \"mutant\": \"E\", \"escape\": 0.013182599766692211, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.3373, \"times_seen\": 3.0}, {\"site\": 127, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -2.9735, \"times_seen\": null}, {\"site\": 127, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 127, \"mutant\": \"M\", \"escape\": -0.008433968564250131, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 127, \"mutant\": \"N\", \"escape\": -0.08469436992280721, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 127, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 127, \"mutant\": \"R\", \"escape\": -0.1785973380418152, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.0909, \"times_seen\": 50.0}, {\"site\": 127, \"mutant\": \"T\", \"escape\": 0.01498977893722827, \"epitope\": \"epitope 1\", \"reference_site\": \"129\", \"functional effect\": -0.2494, \"times_seen\": 9.0}, {\"site\": 128, \"mutant\": \"A\", \"escape\": 0.010129578318212241, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.4587, \"times_seen\": 16.0}, {\"site\": 128, \"mutant\": \"F\", \"escape\": 0.0110544210689196, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.4335, \"times_seen\": 29.0}, {\"site\": 128, \"mutant\": \"I\", \"escape\": -0.04395926844160298, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.2335, \"times_seen\": 10.0}, {\"site\": 128, \"mutant\": \"L\", \"escape\": -0.0012136001738547234, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.1666, \"times_seen\": 23.0}, {\"site\": 128, \"mutant\": \"M\", \"escape\": 0.017118032294005894, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.4105, \"times_seen\": 7.0}, {\"site\": 128, \"mutant\": \"S\", \"escape\": 0.013438305419988469, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.8318, \"times_seen\": 10.0}, {\"site\": 128, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 128, \"mutant\": \"Y\", \"escape\": -0.018444120505775007, \"epitope\": \"epitope 1\", \"reference_site\": \"130\", \"functional effect\": -0.3397, \"times_seen\": 9.0}, {\"site\": 129, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -3.2644, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.2294, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -3.2541, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"R\", \"escape\": -0.003473783186503196, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.8472, \"times_seen\": 1.0}, {\"site\": 129, \"mutant\": \"S\", \"escape\": 0.015709485794407854, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.2664, \"times_seen\": 2.0}, {\"site\": 129, \"mutant\": \"V\", \"escape\": -0.006747071130340286, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -1.8136, \"times_seen\": 3.0}, {\"site\": 129, \"mutant\": \"Y\", \"escape\": -0.015182737053433235, \"epitope\": \"epitope 1\", \"reference_site\": \"131\", \"functional effect\": -2.3392, \"times_seen\": 2.0}, {\"site\": 130, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -2.9703, \"times_seen\": null}, {\"site\": 130, \"mutant\": \"A\", \"escape\": 0.04317895693558684, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.0898, \"times_seen\": 42.0}, {\"site\": 130, \"mutant\": \"D\", \"escape\": -0.09397075489411727, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -0.0837, \"times_seen\": 81.0}, {\"site\": 130, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 130, \"mutant\": \"G\", \"escape\": -0.01208912737073434, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -0.2183, \"times_seen\": 15.0}, {\"site\": 130, \"mutant\": \"K\", \"escape\": 0.10255231616738837, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.3539, \"times_seen\": 41.0}, {\"site\": 130, \"mutant\": \"N\", \"escape\": 0.011519244308266612, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": -0.1598, \"times_seen\": 9.0}, {\"site\": 130, \"mutant\": \"Q\", \"escape\": -0.09777542706946211, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.2681, \"times_seen\": 59.0}, {\"site\": 130, \"mutant\": \"V\", \"escape\": -0.02384797664167158, \"epitope\": \"epitope 1\", \"reference_site\": \"132\", \"functional effect\": 0.3141, \"times_seen\": 16.0}, {\"site\": 131, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -3.2642, \"times_seen\": null}, {\"site\": 131, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 131, \"mutant\": \"I\", \"escape\": 0.0014995864752773127, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -0.1434, \"times_seen\": 24.0}, {\"site\": 131, \"mutant\": \"L\", \"escape\": -0.046753398766923145, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -0.2888, \"times_seen\": 16.0}, {\"site\": 131, \"mutant\": \"S\", \"escape\": -0.02106649002422025, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -1.5164, \"times_seen\": 8.0}, {\"site\": 131, \"mutant\": \"Y\", \"escape\": 0.12889927007648716, \"epitope\": \"epitope 1\", \"reference_site\": \"133\", \"functional effect\": -0.1178, \"times_seen\": 18.0}, {\"site\": 132, \"mutant\": \"*\", \"escape\": -0.004517542794977378, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -2.8438, \"times_seen\": 1.0}, {\"site\": 132, \"mutant\": \"E\", \"escape\": 0.14234329553363548, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": 0.125, \"times_seen\": 41.0}, {\"site\": 132, \"mutant\": \"H\", \"escape\": -0.2722446567403487, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0731, \"times_seen\": 137.0}, {\"site\": 132, \"mutant\": \"K\", \"escape\": -0.07366919998395587, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0553, \"times_seen\": 29.0}, {\"site\": 132, \"mutant\": \"L\", \"escape\": -0.009177267546751437, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.1193, \"times_seen\": 144.0}, {\"site\": 132, \"mutant\": \"N\", \"escape\": -0.0778709718901581, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": 0.0087, \"times_seen\": 9.0}, {\"site\": 132, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.5534, \"times_seen\": null}, {\"site\": 132, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 132, \"mutant\": \"R\", \"escape\": 0.03410675934423081, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0991, \"times_seen\": 47.0}, {\"site\": 132, \"mutant\": \"S\", \"escape\": -0.026046670671489257, \"epitope\": \"epitope 1\", \"reference_site\": \"134\", \"functional effect\": -0.0935, \"times_seen\": 10.0}, {\"site\": 133, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 133, \"mutant\": \"I\", \"escape\": -0.04900287281660659, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.0108, \"times_seen\": 37.0}, {\"site\": 133, \"mutant\": \"L\", \"escape\": -0.027699027225979313, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.0847, \"times_seen\": 42.0}, {\"site\": 133, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 133, \"mutant\": \"S\", \"escape\": -0.01647515025223173, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.3028, \"times_seen\": 4.0}, {\"site\": 133, \"mutant\": \"V\", \"escape\": 0.035541200300595634, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.068, \"times_seen\": 12.0}, {\"site\": 133, \"mutant\": \"Y\", \"escape\": -0.07177713990981865, \"epitope\": \"epitope 1\", \"reference_site\": \"135\", \"functional effect\": -0.0252, \"times_seen\": 26.0}, {\"site\": 134, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": 0.2867, \"times_seen\": null}, {\"site\": 134, \"mutant\": \"-\", \"escape\": 0.04612274727623811, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.1883, \"times_seen\": 17.0}, {\"site\": 134, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 134, \"mutant\": \"F\", \"escape\": 0.048276538676948165, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0199, \"times_seen\": 87.0}, {\"site\": 134, \"mutant\": \"G\", \"escape\": 0.023708962918437618, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.1983, \"times_seen\": 13.0}, {\"site\": 134, \"mutant\": \"L\", \"escape\": -0.8801894003356839, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0987, \"times_seen\": 16.0}, {\"site\": 134, \"mutant\": \"R\", \"escape\": 0.021022210539469337, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0854, \"times_seen\": 15.0}, {\"site\": 134, \"mutant\": \"S\", \"escape\": -0.035110675712573675, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.2441, \"times_seen\": 16.0}, {\"site\": 134, \"mutant\": \"V\", \"escape\": -0.003870525696866601, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.1774, \"times_seen\": 6.0}, {\"site\": 134, \"mutant\": \"W\", \"escape\": -0.01938873918274288, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 134, \"mutant\": \"Y\", \"escape\": -0.04353200101629356, \"epitope\": \"epitope 1\", \"reference_site\": \"136\", \"functional effect\": -0.0384, \"times_seen\": 43.0}, {\"site\": 135, \"mutant\": \"-\", \"escape\": 0.004243796192654157, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.1167, \"times_seen\": 7.0}, {\"site\": 135, \"mutant\": \"D\", \"escape\": -0.034392688578757116, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.2205, \"times_seen\": 24.0}, {\"site\": 135, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 135, \"mutant\": \"I\", \"escape\": -0.05955909926730995, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.0149, \"times_seen\": 18.0}, {\"site\": 135, \"mutant\": \"K\", \"escape\": -0.020913719725032094, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.073, \"times_seen\": 13.0}, {\"site\": 135, \"mutant\": \"M\", \"escape\": -0.0002391166615605675, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.0814, \"times_seen\": 13.0}, {\"site\": 135, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 135, \"mutant\": \"S\", \"escape\": -4.580985050957895, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.0079, \"times_seen\": 28.0}, {\"site\": 135, \"mutant\": \"T\", \"escape\": -0.01709983135684989, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": 0.2271, \"times_seen\": 9.0}, {\"site\": 135, \"mutant\": \"Y\", \"escape\": -0.045899040183478054, \"epitope\": \"epitope 1\", \"reference_site\": \"137\", \"functional effect\": -0.0102, \"times_seen\": 26.0}, {\"site\": 136, \"mutant\": \"*\", \"escape\": -0.0003524503114182896, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -2.988, \"times_seen\": 1.0}, {\"site\": 136, \"mutant\": \"-\", \"escape\": -0.003731208071032315, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0355, \"times_seen\": 2.0}, {\"site\": 136, \"mutant\": \"A\", \"escape\": -0.5739808937234971, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0073, \"times_seen\": 185.0}, {\"site\": 136, \"mutant\": \"C\", \"escape\": -0.04972498260191588, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.1698, \"times_seen\": 32.0}, {\"site\": 136, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 136, \"mutant\": \"E\", \"escape\": 0.051562967893416994, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0292, \"times_seen\": 71.0}, {\"site\": 136, \"mutant\": \"F\", \"escape\": 0.05398227086118952, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0714, \"times_seen\": 35.0}, {\"site\": 136, \"mutant\": \"G\", \"escape\": -0.2034141498786291, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0135, \"times_seen\": 127.0}, {\"site\": 136, \"mutant\": \"H\", \"escape\": 0.38760073828216035, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.0006, \"times_seen\": 106.0}, {\"site\": 136, \"mutant\": \"I\", \"escape\": -0.05664782417266875, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0646, \"times_seen\": 50.0}, {\"site\": 136, \"mutant\": \"K\", \"escape\": -0.02772079073055826, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0658, \"times_seen\": 32.0}, {\"site\": 136, \"mutant\": \"L\", \"escape\": 0.790023657641868, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0911, \"times_seen\": 81.0}, {\"site\": 136, \"mutant\": \"M\", \"escape\": -0.07430753434613786, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0307, \"times_seen\": 23.0}, {\"site\": 136, \"mutant\": \"N\", \"escape\": -0.0085337022914076, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0782, \"times_seen\": 125.0}, {\"site\": 136, \"mutant\": \"P\", \"escape\": 0.4618953881861476, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0112, \"times_seen\": 104.0}, {\"site\": 136, \"mutant\": \"Q\", \"escape\": -0.04422146265863966, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": 0.099, \"times_seen\": 39.0}, {\"site\": 136, \"mutant\": \"R\", \"escape\": -0.7963273145721899, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.1031, \"times_seen\": 85.0}, {\"site\": 136, \"mutant\": \"S\", \"escape\": 0.0268232667852942, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0089, \"times_seen\": 115.0}, {\"site\": 136, \"mutant\": \"T\", \"escape\": 0.010106887577475954, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0597, \"times_seen\": 94.0}, {\"site\": 136, \"mutant\": \"V\", \"escape\": -0.0050600120205425165, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0432, \"times_seen\": 76.0}, {\"site\": 136, \"mutant\": \"W\", \"escape\": 0.09932583615976079, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.0004, \"times_seen\": 22.0}, {\"site\": 136, \"mutant\": \"Y\", \"escape\": -0.17978776585293657, \"epitope\": \"epitope 1\", \"reference_site\": \"138\", \"functional effect\": -0.1254, \"times_seen\": 108.0}, {\"site\": 137, \"mutant\": \"-\", \"escape\": -0.009399612751551215, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": 0.0539, \"times_seen\": 7.0}, {\"site\": 137, \"mutant\": \"A\", \"escape\": -0.007140119249250305, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": 0.1536, \"times_seen\": 2.0}, {\"site\": 137, \"mutant\": \"H\", \"escape\": 0.0016364595231610098, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.1663, \"times_seen\": 14.0}, {\"site\": 137, \"mutant\": \"L\", \"escape\": -0.8404680173576481, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.0056, \"times_seen\": 52.0}, {\"site\": 137, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 137, \"mutant\": \"Q\", \"escape\": -0.011349232404528802, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.0651, \"times_seen\": 13.0}, {\"site\": 137, \"mutant\": \"S\", \"escape\": -0.026494919499663434, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.0358, \"times_seen\": 34.0}, {\"site\": 137, \"mutant\": \"T\", \"escape\": -0.019120892790168053, \"epitope\": \"epitope 1\", \"reference_site\": \"139\", \"functional effect\": -0.1179, \"times_seen\": 16.0}, {\"site\": 138, \"mutant\": \"-\", \"escape\": -0.041735650560885594, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.0078, \"times_seen\": 34.0}, {\"site\": 138, \"mutant\": \"C\", \"escape\": -0.01181258339218416, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 138, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 138, \"mutant\": \"I\", \"escape\": 0.024925276156403386, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": -0.0353, \"times_seen\": 20.0}, {\"site\": 138, \"mutant\": \"L\", \"escape\": -0.027165569271484225, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": -0.0265, \"times_seen\": 28.0}, {\"site\": 138, \"mutant\": \"S\", \"escape\": 0.04124936204820362, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": -0.134, \"times_seen\": 10.0}, {\"site\": 138, \"mutant\": \"V\", \"escape\": 0.019927903927061705, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.2253, \"times_seen\": 3.0}, {\"site\": 138, \"mutant\": \"Y\", \"escape\": -0.02997242374141297, \"epitope\": \"epitope 1\", \"reference_site\": \"140\", \"functional effect\": 0.0353, \"times_seen\": 32.0}, {\"site\": 139, \"mutant\": \"-\", \"escape\": 0.026592734419165934, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.0929, \"times_seen\": 18.0}, {\"site\": 139, \"mutant\": \"F\", \"escape\": -0.0005756454621253041, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.1315, \"times_seen\": 42.0}, {\"site\": 139, \"mutant\": \"I\", \"escape\": -0.0014630563438359499, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.191, \"times_seen\": 11.0}, {\"site\": 139, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 139, \"mutant\": \"M\", \"escape\": -0.021888139903068923, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.1949, \"times_seen\": 25.0}, {\"site\": 139, \"mutant\": \"P\", \"escape\": 0.014125788796246456, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.144, \"times_seen\": 27.0}, {\"site\": 139, \"mutant\": \"Q\", \"escape\": -0.006936621934804578, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.1531, \"times_seen\": 4.0}, {\"site\": 139, \"mutant\": \"R\", \"escape\": -0.007042194162833322, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.2015, \"times_seen\": 2.0}, {\"site\": 139, \"mutant\": \"S\", \"escape\": -0.014888303315052143, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.0782, \"times_seen\": 10.0}, {\"site\": 139, \"mutant\": \"V\", \"escape\": -0.14675021364021204, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": -0.0493, \"times_seen\": 16.0}, {\"site\": 139, \"mutant\": \"W\", \"escape\": -0.007548491250955708, \"epitope\": \"epitope 1\", \"reference_site\": \"141\", \"functional effect\": 0.2301, \"times_seen\": 15.0}, {\"site\": 140, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 140, \"mutant\": \"-\", \"escape\": 0.013635715623883493, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0809, \"times_seen\": 14.0}, {\"site\": 140, \"mutant\": \"A\", \"escape\": -0.11662265045502457, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0645, \"times_seen\": 145.0}, {\"site\": 140, \"mutant\": \"C\", \"escape\": -0.16762010252301587, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1518, \"times_seen\": 140.0}, {\"site\": 140, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 140, \"mutant\": \"E\", \"escape\": 0.2517578514475449, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0027, \"times_seen\": 66.0}, {\"site\": 140, \"mutant\": \"F\", \"escape\": -0.008493110633418984, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0629, \"times_seen\": 32.0}, {\"site\": 140, \"mutant\": \"G\", \"escape\": -0.44971532123526736, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1234, \"times_seen\": 121.0}, {\"site\": 140, \"mutant\": \"H\", \"escape\": -0.04494177435454922, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1008, \"times_seen\": 77.0}, {\"site\": 140, \"mutant\": \"I\", \"escape\": 0.0213375846865349, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0047, \"times_seen\": 50.0}, {\"site\": 140, \"mutant\": \"K\", \"escape\": 0.07997906105545788, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.3408, \"times_seen\": 40.0}, {\"site\": 140, \"mutant\": \"L\", \"escape\": -0.4319881193329773, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0144, \"times_seen\": 134.0}, {\"site\": 140, \"mutant\": \"M\", \"escape\": -0.01354933316142874, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0018, \"times_seen\": 49.0}, {\"site\": 140, \"mutant\": \"N\", \"escape\": -0.005913736764491356, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0348, \"times_seen\": 83.0}, {\"site\": 140, \"mutant\": \"P\", \"escape\": 0.3973276111032076, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0264, \"times_seen\": 131.0}, {\"site\": 140, \"mutant\": \"Q\", \"escape\": -0.3200246198495421, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0365, \"times_seen\": 41.0}, {\"site\": 140, \"mutant\": \"R\", \"escape\": 0.26762862547666394, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.3689, \"times_seen\": 113.0}, {\"site\": 140, \"mutant\": \"S\", \"escape\": -0.01335232702330046, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1074, \"times_seen\": 207.0}, {\"site\": 140, \"mutant\": \"T\", \"escape\": 0.2185381872774377, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0065, \"times_seen\": 93.0}, {\"site\": 140, \"mutant\": \"V\", \"escape\": -0.4481947183351947, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.0163, \"times_seen\": 89.0}, {\"site\": 140, \"mutant\": \"W\", \"escape\": 0.09983557408424874, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": 0.0605, \"times_seen\": 32.0}, {\"site\": 140, \"mutant\": \"Y\", \"escape\": 0.013043343349898377, \"epitope\": \"epitope 1\", \"reference_site\": \"142\", \"functional effect\": -0.1328, \"times_seen\": 82.0}, {\"site\": 141, \"mutant\": \"-\", \"escape\": -0.007125921562860772, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0301, \"times_seen\": 14.0}, {\"site\": 141, \"mutant\": \"D\", \"escape\": -0.14428125945196552, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.168, \"times_seen\": 10.0}, {\"site\": 141, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 141, \"mutant\": \"K\", \"escape\": -0.004314083865733396, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.1113, \"times_seen\": 14.0}, {\"site\": 141, \"mutant\": \"L\", \"escape\": -0.011374287775102973, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0101, \"times_seen\": 33.0}, {\"site\": 141, \"mutant\": \"N\", \"escape\": -0.012632434590021535, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0471, \"times_seen\": 80.0}, {\"site\": 141, \"mutant\": \"P\", \"escape\": 0.021454187970789417, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.1253, \"times_seen\": 19.0}, {\"site\": 141, \"mutant\": \"Q\", \"escape\": -0.009397166457367061, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.0047, \"times_seen\": 46.0}, {\"site\": 141, \"mutant\": \"R\", \"escape\": -0.0316129255958514, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": 0.0445, \"times_seen\": 11.0}, {\"site\": 141, \"mutant\": \"S\", \"escape\": 0.015795555802141894, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0282, \"times_seen\": 8.0}, {\"site\": 141, \"mutant\": \"T\", \"escape\": 0.12109408111010993, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.06, \"times_seen\": 15.0}, {\"site\": 141, \"mutant\": \"Y\", \"escape\": -0.009699627253381778, \"epitope\": \"epitope 1\", \"reference_site\": \"146\", \"functional effect\": -0.0143, \"times_seen\": 87.0}, {\"site\": 142, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.8951, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"A\", \"escape\": 1.8827985983456652e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0112, \"times_seen\": 1.0}, {\"site\": 142, \"mutant\": \"E\", \"escape\": -0.33167642905059874, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0494, \"times_seen\": 76.0}, {\"site\": 142, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"I\", \"escape\": -0.05021773560017087, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0829, \"times_seen\": 21.0}, {\"site\": 142, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"M\", \"escape\": -0.014228546417753372, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.2134, \"times_seen\": 5.0}, {\"site\": 142, \"mutant\": \"N\", \"escape\": -0.09656248459943576, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0867, \"times_seen\": 79.0}, {\"site\": 142, \"mutant\": \"P\", \"escape\": -0.012195193956524472, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.1616, \"times_seen\": 4.0}, {\"site\": 142, \"mutant\": \"Q\", \"escape\": 0.002819360022321155, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -0.0244, \"times_seen\": 39.0}, {\"site\": 142, \"mutant\": \"R\", \"escape\": -0.010510167695976147, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": 0.0635, \"times_seen\": 62.0}, {\"site\": 142, \"mutant\": \"T\", \"escape\": -0.029613534080583148, \"epitope\": \"epitope 1\", \"reference_site\": \"147\", \"functional effect\": -0.0491, \"times_seen\": 11.0}, {\"site\": 143, \"mutant\": \"-\", \"escape\": 0.009917709447677576, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.0551, \"times_seen\": 17.0}, {\"site\": 143, \"mutant\": \"D\", \"escape\": 0.061826756122574884, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0116, \"times_seen\": 62.0}, {\"site\": 143, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.2116, \"times_seen\": null}, {\"site\": 143, \"mutant\": \"H\", \"escape\": 0.08019759293468227, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.0741, \"times_seen\": 21.0}, {\"site\": 143, \"mutant\": \"K\", \"escape\": -0.04031181919087026, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.1002, \"times_seen\": 46.0}, {\"site\": 143, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 143, \"mutant\": \"Q\", \"escape\": 0.03784396012237066, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": -0.0122, \"times_seen\": 17.0}, {\"site\": 143, \"mutant\": \"S\", \"escape\": 0.22303478449394085, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0886, \"times_seen\": 75.0}, {\"site\": 143, \"mutant\": \"T\", \"escape\": 0.005272499139367191, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0449, \"times_seen\": 108.0}, {\"site\": 143, \"mutant\": \"Y\", \"escape\": 0.09724494347417632, \"epitope\": \"epitope 1\", \"reference_site\": \"148\", \"functional effect\": 0.0044, \"times_seen\": 52.0}, {\"site\": 144, \"mutant\": \"D\", \"escape\": -0.0012381866104210326, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.0678, \"times_seen\": 14.0}, {\"site\": 144, \"mutant\": \"H\", \"escape\": -0.002231501320762805, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0107, \"times_seen\": 26.0}, {\"site\": 144, \"mutant\": \"I\", \"escape\": -0.048008110681130804, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.1116, \"times_seen\": 25.0}, {\"site\": 144, \"mutant\": \"K\", \"escape\": -0.0019302637749869752, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0619, \"times_seen\": 11.0}, {\"site\": 144, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 144, \"mutant\": \"Q\", \"escape\": -0.026174875189790527, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.1299, \"times_seen\": 13.0}, {\"site\": 144, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.2256, \"times_seen\": null}, {\"site\": 144, \"mutant\": \"S\", \"escape\": 0.022781803511503607, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0286, \"times_seen\": 21.0}, {\"site\": 144, \"mutant\": \"T\", \"escape\": -0.021222610790894377, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": 0.0276, \"times_seen\": 16.0}, {\"site\": 144, \"mutant\": \"Y\", \"escape\": -0.038195113078620224, \"epitope\": \"epitope 1\", \"reference_site\": \"149\", \"functional effect\": -0.0154, \"times_seen\": 23.0}, {\"site\": 145, \"mutant\": \"-\", \"escape\": 0.00865777554567474, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.1374, \"times_seen\": 33.0}, {\"site\": 145, \"mutant\": \"E\", \"escape\": 0.012869447941089567, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0949, \"times_seen\": 50.0}, {\"site\": 145, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 145, \"mutant\": \"I\", \"escape\": -0.04462162145833193, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0173, \"times_seen\": 53.0}, {\"site\": 145, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 145, \"mutant\": \"N\", \"escape\": -0.07429795113491376, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0648, \"times_seen\": 66.0}, {\"site\": 145, \"mutant\": \"Q\", \"escape\": -0.02018287094951825, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.1539, \"times_seen\": 11.0}, {\"site\": 145, \"mutant\": \"R\", \"escape\": -0.02869514889541808, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0102, \"times_seen\": 23.0}, {\"site\": 145, \"mutant\": \"T\", \"escape\": -0.00814726724200056, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": 0.0316, \"times_seen\": 23.0}, {\"site\": 145, \"mutant\": \"V\", \"escape\": 0.0004963857624746461, \"epitope\": \"epitope 1\", \"reference_site\": \"150\", \"functional effect\": -0.1884, \"times_seen\": 11.0}, {\"site\": 146, \"mutant\": \"-\", \"escape\": 0.005747861417976551, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.1256, \"times_seen\": 13.0}, {\"site\": 146, \"mutant\": \"C\", \"escape\": 0.08221014488930106, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.3201, \"times_seen\": 14.0}, {\"site\": 146, \"mutant\": \"F\", \"escape\": -0.0023894310493272368, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.7801, \"times_seen\": 1.0}, {\"site\": 146, \"mutant\": \"G\", \"escape\": 0.00518026626939557, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.1226, \"times_seen\": 28.0}, {\"site\": 146, \"mutant\": \"I\", \"escape\": 0.04637935109848061, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.2093, \"times_seen\": 34.0}, {\"site\": 146, \"mutant\": \"K\", \"escape\": -0.012515459301612181, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.205, \"times_seen\": 6.0}, {\"site\": 146, \"mutant\": \"N\", \"escape\": 0.7613718530421177, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.0894, \"times_seen\": 44.0}, {\"site\": 146, \"mutant\": \"P\", \"escape\": -0.011674216947624905, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.3216, \"times_seen\": 4.0}, {\"site\": 146, \"mutant\": \"Q\", \"escape\": 0.022949747806348866, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.0198, \"times_seen\": 6.0}, {\"site\": 146, \"mutant\": \"R\", \"escape\": 0.017356040407541826, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.1366, \"times_seen\": 9.0}, {\"site\": 146, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 146, \"mutant\": \"T\", \"escape\": -0.03668382133579459, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.0105, \"times_seen\": 51.0}, {\"site\": 146, \"mutant\": \"V\", \"escape\": -0.008823389478680185, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": -0.2935, \"times_seen\": 9.0}, {\"site\": 146, \"mutant\": \"Y\", \"escape\": -0.012740785858046113, \"epitope\": \"epitope 1\", \"reference_site\": \"151\", \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 147, \"mutant\": \"*\", \"escape\": 0.34148334956209886, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -2.6709, \"times_seen\": 6.0}, {\"site\": 147, \"mutant\": \"-\", \"escape\": -0.010502266866389859, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.1988, \"times_seen\": 6.0}, {\"site\": 147, \"mutant\": \"C\", \"escape\": -0.01946040948706856, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.1035, \"times_seen\": 58.0}, {\"site\": 147, \"mutant\": \"F\", \"escape\": 0.0027027994443314047, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.2968, \"times_seen\": 8.0}, {\"site\": 147, \"mutant\": \"G\", \"escape\": 0.07390590960050517, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.056, \"times_seen\": 16.0}, {\"site\": 147, \"mutant\": \"K\", \"escape\": -0.02207222517701258, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.1747, \"times_seen\": 15.0}, {\"site\": 147, \"mutant\": \"L\", \"escape\": -0.019746478810637715, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.0578, \"times_seen\": 68.0}, {\"site\": 147, \"mutant\": \"R\", \"escape\": 0.5304631681428431, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.0097, \"times_seen\": 66.0}, {\"site\": 147, \"mutant\": \"S\", \"escape\": 0.15011913964332152, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.0447, \"times_seen\": 47.0}, {\"site\": 147, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": -0.7731, \"times_seen\": null}, {\"site\": 147, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 147, \"mutant\": \"Y\", \"escape\": 0.0034870063002883185, \"epitope\": \"epitope 1\", \"reference_site\": \"152\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 148, \"mutant\": \"-\", \"escape\": -0.015852136497276473, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": -0.0214, \"times_seen\": 13.0}, {\"site\": 148, \"mutant\": \"I\", \"escape\": -0.14408675005481789, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0462, \"times_seen\": 82.0}, {\"site\": 148, \"mutant\": \"K\", \"escape\": 0.012037130258750521, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": -0.2152, \"times_seen\": 13.0}, {\"site\": 148, \"mutant\": \"L\", \"escape\": 0.02593950199835513, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0377, \"times_seen\": 60.0}, {\"site\": 148, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 148, \"mutant\": \"R\", \"escape\": -0.009014467700435281, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0217, \"times_seen\": 15.0}, {\"site\": 148, \"mutant\": \"T\", \"escape\": -0.056981713180392995, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 148, \"mutant\": \"V\", \"escape\": -0.3634636426385986, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.0424, \"times_seen\": 41.0}, {\"site\": 148, \"mutant\": \"W\", \"escape\": 0.03019729345719767, \"epitope\": \"epitope 1\", \"reference_site\": \"153\", \"functional effect\": 0.1417, \"times_seen\": 11.0}, {\"site\": 149, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -2.9301, \"times_seen\": null}, {\"site\": 149, \"mutant\": \"-\", \"escape\": -0.07408129219199638, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.0626, \"times_seen\": 31.0}, {\"site\": 149, \"mutant\": \"A\", \"escape\": -0.6177960574793068, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0613, \"times_seen\": 38.0}, {\"site\": 149, \"mutant\": \"D\", \"escape\": -0.0003984661992364731, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0981, \"times_seen\": 17.0}, {\"site\": 149, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 149, \"mutant\": \"G\", \"escape\": -0.011876709868923844, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.1528, \"times_seen\": 52.0}, {\"site\": 149, \"mutant\": \"K\", \"escape\": 0.037742391593511705, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.1484, \"times_seen\": 73.0}, {\"site\": 149, \"mutant\": \"Q\", \"escape\": 0.02149181548383207, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.0372, \"times_seen\": 72.0}, {\"site\": 149, \"mutant\": \"S\", \"escape\": 0.001644557377000585, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": -0.1094, \"times_seen\": 14.0}, {\"site\": 149, \"mutant\": \"V\", \"escape\": 0.046860300663323244, \"epitope\": \"epitope 1\", \"reference_site\": \"154\", \"functional effect\": 0.0753, \"times_seen\": 14.0}, {\"site\": 150, \"mutant\": \"-\", \"escape\": -0.006604025993475734, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.0872, \"times_seen\": 18.0}, {\"site\": 150, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -3.1878, \"times_seen\": null}, {\"site\": 150, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.2891, \"times_seen\": null}, {\"site\": 150, \"mutant\": \"G\", \"escape\": -0.0058313197545934725, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.0684, \"times_seen\": 19.0}, {\"site\": 150, \"mutant\": \"I\", \"escape\": -0.035270145006214046, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.1026, \"times_seen\": 54.0}, {\"site\": 150, \"mutant\": \"K\", \"escape\": 0.0006552400532199255, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.0315, \"times_seen\": 19.0}, {\"site\": 150, \"mutant\": \"N\", \"escape\": -0.09910750511319556, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.1457, \"times_seen\": 39.0}, {\"site\": 150, \"mutant\": \"P\", \"escape\": -0.0054129421894732145, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.4192, \"times_seen\": 7.0}, {\"site\": 150, \"mutant\": \"R\", \"escape\": 0.011929817463843627, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.025, \"times_seen\": 24.0}, {\"site\": 150, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 150, \"mutant\": \"T\", \"escape\": -0.01858603854105188, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": 0.2218, \"times_seen\": 8.0}, {\"site\": 150, \"mutant\": \"V\", \"escape\": -0.19561628723959673, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.1881, \"times_seen\": 11.0}, {\"site\": 150, \"mutant\": \"Y\", \"escape\": -0.013135423024260283, \"epitope\": \"epitope 1\", \"reference_site\": \"155\", \"functional effect\": -0.183, \"times_seen\": 10.0}, {\"site\": 151, \"mutant\": \"*\", \"escape\": -0.005925292879978943, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -2.2596, \"times_seen\": 1.0}, {\"site\": 151, \"mutant\": \"-\", \"escape\": 0.03158033016868314, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.348, \"times_seen\": 25.0}, {\"site\": 151, \"mutant\": \"A\", \"escape\": 0.009731805142180366, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.2672, \"times_seen\": 13.0}, {\"site\": 151, \"mutant\": \"D\", \"escape\": 0.2740859684443174, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.0483, \"times_seen\": 64.0}, {\"site\": 151, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 151, \"mutant\": \"G\", \"escape\": 0.016494636861596124, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.1704, \"times_seen\": 25.0}, {\"site\": 151, \"mutant\": \"K\", \"escape\": -0.021932035688415643, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.011, \"times_seen\": 27.0}, {\"site\": 151, \"mutant\": \"Q\", \"escape\": 0.02267346477947984, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.0518, \"times_seen\": 39.0}, {\"site\": 151, \"mutant\": \"V\", \"escape\": 0.0797185948124298, \"epitope\": \"epitope 1\", \"reference_site\": \"156\", \"functional effect\": -0.0439, \"times_seen\": 27.0}, {\"site\": 152, \"mutant\": \"*\", \"escape\": -0.0049728175618521464, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -2.1956, \"times_seen\": 3.0}, {\"site\": 152, \"mutant\": \"-\", \"escape\": -0.06321658859663613, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0351, \"times_seen\": 24.0}, {\"site\": 152, \"mutant\": \"A\", \"escape\": 0.1430108567183445, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0147, \"times_seen\": 109.0}, {\"site\": 152, \"mutant\": \"C\", \"escape\": -0.02797975173886771, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0333, \"times_seen\": 96.0}, {\"site\": 152, \"mutant\": \"D\", \"escape\": -0.015726044841222087, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0643, \"times_seen\": 47.0}, {\"site\": 152, \"mutant\": \"E\", \"escape\": -0.01599363184139991, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.1051, \"times_seen\": 6.0}, {\"site\": 152, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 152, \"mutant\": \"G\", \"escape\": -0.13792089095153484, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0596, \"times_seen\": 71.0}, {\"site\": 152, \"mutant\": \"H\", \"escape\": 0.06568451849891606, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.1837, \"times_seen\": 76.0}, {\"site\": 152, \"mutant\": \"I\", \"escape\": 0.2284651175605084, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0831, \"times_seen\": 84.0}, {\"site\": 152, \"mutant\": \"K\", \"escape\": 0.06565145930717345, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.1089, \"times_seen\": 26.0}, {\"site\": 152, \"mutant\": \"L\", \"escape\": 0.07127325141604458, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0042, \"times_seen\": 226.0}, {\"site\": 152, \"mutant\": \"M\", \"escape\": -0.045735045358169205, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.1247, \"times_seen\": 27.0}, {\"site\": 152, \"mutant\": \"N\", \"escape\": 0.6525818588644254, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.06, \"times_seen\": 53.0}, {\"site\": 152, \"mutant\": \"P\", \"escape\": -0.14276256480809474, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0087, \"times_seen\": 136.0}, {\"site\": 152, \"mutant\": \"Q\", \"escape\": 0.004284652473214403, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0048, \"times_seen\": 49.0}, {\"site\": 152, \"mutant\": \"R\", \"escape\": 0.005574227804898936, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": -0.0804, \"times_seen\": 106.0}, {\"site\": 152, \"mutant\": \"S\", \"escape\": -0.04009306046206218, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0097, \"times_seen\": 255.0}, {\"site\": 152, \"mutant\": \"T\", \"escape\": -0.4572659276375866, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0486, \"times_seen\": 93.0}, {\"site\": 152, \"mutant\": \"V\", \"escape\": -0.09751726335353043, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.01, \"times_seen\": 83.0}, {\"site\": 152, \"mutant\": \"W\", \"escape\": -0.025869293119868967, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.1925, \"times_seen\": 31.0}, {\"site\": 152, \"mutant\": \"Y\", \"escape\": -0.24003373036553555, \"epitope\": \"epitope 1\", \"reference_site\": \"157\", \"functional effect\": 0.0065, \"times_seen\": 94.0}, {\"site\": 153, \"mutant\": \"-\", \"escape\": -0.007887556267663961, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": -0.1961, \"times_seen\": 29.0}, {\"site\": 153, \"mutant\": \"G\", \"escape\": -0.4218386200413686, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.075, \"times_seen\": 54.0}, {\"site\": 153, \"mutant\": \"I\", \"escape\": -0.05394136793174843, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.1199, \"times_seen\": 64.0}, {\"site\": 153, \"mutant\": \"K\", \"escape\": -0.0022674333687032694, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.0516, \"times_seen\": 28.0}, {\"site\": 153, \"mutant\": \"M\", \"escape\": 0.01062054059975005, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.0289, \"times_seen\": 19.0}, {\"site\": 153, \"mutant\": \"N\", \"escape\": 0.7198221479189083, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.1885, \"times_seen\": 23.0}, {\"site\": 153, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 153, \"mutant\": \"S\", \"escape\": 0.3206490354428876, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.086, \"times_seen\": 65.0}, {\"site\": 153, \"mutant\": \"T\", \"escape\": 0.1461183059187884, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.044, \"times_seen\": 18.0}, {\"site\": 153, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"158\", \"functional effect\": 0.27, \"times_seen\": null}, {\"site\": 154, \"mutant\": \"-\", \"escape\": 0.009159875396071673, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": 0.128, \"times_seen\": 20.0}, {\"site\": 154, \"mutant\": \"A\", \"escape\": -0.03318694933177191, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.1293, \"times_seen\": 32.0}, {\"site\": 154, \"mutant\": \"F\", \"escape\": -0.0978743003369825, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0272, \"times_seen\": 44.0}, {\"site\": 154, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0379, \"times_seen\": null}, {\"site\": 154, \"mutant\": \"I\", \"escape\": 0.7212553277619111, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0127, \"times_seen\": 41.0}, {\"site\": 154, \"mutant\": \"L\", \"escape\": 0.011692173869035921, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": 0.1168, \"times_seen\": 16.0}, {\"site\": 154, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 154, \"mutant\": \"Y\", \"escape\": 0.014683461827754972, \"epitope\": \"epitope 1\", \"reference_site\": \"159\", \"functional effect\": -0.0122, \"times_seen\": 1.0}, {\"site\": 155, \"mutant\": \"*\", \"escape\": -0.0028301760909669534, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -2.7036, \"times_seen\": 1.0}, {\"site\": 155, \"mutant\": \"-\", \"escape\": -0.03626213735137438, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.2207, \"times_seen\": 21.0}, {\"site\": 155, \"mutant\": \"C\", \"escape\": -0.03107125582289602, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.3634, \"times_seen\": 24.0}, {\"site\": 155, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 155, \"mutant\": \"F\", \"escape\": -0.058352636885798684, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.0013, \"times_seen\": 18.0}, {\"site\": 155, \"mutant\": \"H\", \"escape\": -0.009162185591099156, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.025, \"times_seen\": 66.0}, {\"site\": 155, \"mutant\": \"I\", \"escape\": -0.0032223729287967997, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.1281, \"times_seen\": 22.0}, {\"site\": 155, \"mutant\": \"N\", \"escape\": 0.00912377283649641, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.5272, \"times_seen\": 3.0}, {\"site\": 155, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 155, \"mutant\": \"V\", \"escape\": 0.02363500045905148, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": -0.4175, \"times_seen\": 8.0}, {\"site\": 155, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"160\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 156, \"mutant\": \"-\", \"escape\": 0.018028470320001058, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.0075, \"times_seen\": 19.0}, {\"site\": 156, \"mutant\": \"A\", \"escape\": -0.03281012809267535, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.1208, \"times_seen\": 13.0}, {\"site\": 156, \"mutant\": \"F\", \"escape\": -0.06514250996534059, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.0904, \"times_seen\": 94.0}, {\"site\": 156, \"mutant\": \"P\", \"escape\": -0.04262202351976603, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 156, \"mutant\": \"R\", \"escape\": -0.011383906717614188, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.0846, \"times_seen\": 10.0}, {\"site\": 156, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 156, \"mutant\": \"T\", \"escape\": -0.014282952948653789, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": -0.1456, \"times_seen\": 32.0}, {\"site\": 156, \"mutant\": \"Y\", \"escape\": -0.1310215862850839, \"epitope\": \"epitope 1\", \"reference_site\": \"161\", \"functional effect\": 0.066, \"times_seen\": 26.0}, {\"site\": 157, \"mutant\": \"-\", \"escape\": 0.22412811644765193, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.1466, \"times_seen\": 26.0}, {\"site\": 157, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -2.4732, \"times_seen\": null}, {\"site\": 157, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 157, \"mutant\": \"F\", \"escape\": -0.010799711572199944, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.1564, \"times_seen\": 9.0}, {\"site\": 157, \"mutant\": \"G\", \"escape\": 0.04712711107293841, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.1405, \"times_seen\": 15.0}, {\"site\": 157, \"mutant\": \"I\", \"escape\": -0.031430771478543985, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.0007, \"times_seen\": 89.0}, {\"site\": 157, \"mutant\": \"L\", \"escape\": 0.20584840948419153, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.2646, \"times_seen\": 18.0}, {\"site\": 157, \"mutant\": \"N\", \"escape\": -0.2442268630654072, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.0073, \"times_seen\": 65.0}, {\"site\": 157, \"mutant\": \"P\", \"escape\": -0.028115957649007702, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.2622, \"times_seen\": 12.0}, {\"site\": 157, \"mutant\": \"R\", \"escape\": 0.0450214596281996, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.008, \"times_seen\": 11.0}, {\"site\": 157, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 157, \"mutant\": \"T\", \"escape\": 0.009359488024685478, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": -0.0481, \"times_seen\": 19.0}, {\"site\": 157, \"mutant\": \"Y\", \"escape\": -0.006033903142188773, \"epitope\": \"epitope 1\", \"reference_site\": \"162\", \"functional effect\": 0.0921, \"times_seen\": 5.0}, {\"site\": 158, \"mutant\": \"-\", \"escape\": 0.0031561957080216965, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0687, \"times_seen\": 20.0}, {\"site\": 158, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 158, \"mutant\": \"D\", \"escape\": -0.002445134250120506, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.033, \"times_seen\": 3.0}, {\"site\": 158, \"mutant\": \"E\", \"escape\": -0.006194288145680521, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.2321, \"times_seen\": 17.0}, {\"site\": 158, \"mutant\": \"G\", \"escape\": 0.02082974911501005, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.047, \"times_seen\": 27.0}, {\"site\": 158, \"mutant\": \"I\", \"escape\": 0.22117751073601602, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": -0.0315, \"times_seen\": 18.0}, {\"site\": 158, \"mutant\": \"L\", \"escape\": -0.056487245382719355, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.099, \"times_seen\": 12.0}, {\"site\": 158, \"mutant\": \"P\", \"escape\": -0.0021085486914813457, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.2722, \"times_seen\": 1.0}, {\"site\": 158, \"mutant\": \"R\", \"escape\": 0.005655323993613637, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 158, \"mutant\": \"S\", \"escape\": 0.09930440128586164, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0681, \"times_seen\": 116.0}, {\"site\": 158, \"mutant\": \"T\", \"escape\": -0.041009673904065305, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0047, \"times_seen\": 96.0}, {\"site\": 158, \"mutant\": \"V\", \"escape\": -0.03486620227654048, \"epitope\": \"epitope 1\", \"reference_site\": \"163\", \"functional effect\": 0.0087, \"times_seen\": 82.0}, {\"site\": 159, \"mutant\": \"-\", \"escape\": 0.014181054103610527, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1313, \"times_seen\": 35.0}, {\"site\": 159, \"mutant\": \"D\", \"escape\": -0.0038346007973044647, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.0898, \"times_seen\": 17.0}, {\"site\": 159, \"mutant\": \"H\", \"escape\": 0.14289853078341858, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": 0.014, \"times_seen\": 51.0}, {\"site\": 159, \"mutant\": \"I\", \"escape\": -0.0078050038321074355, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.2323, \"times_seen\": 16.0}, {\"site\": 159, \"mutant\": \"K\", \"escape\": 0.0800789259613536, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1011, \"times_seen\": 19.0}, {\"site\": 159, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 159, \"mutant\": \"S\", \"escape\": -0.06473650791691002, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1513, \"times_seen\": 28.0}, {\"site\": 159, \"mutant\": \"T\", \"escape\": -0.04300721271927882, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1756, \"times_seen\": 70.0}, {\"site\": 159, \"mutant\": \"Y\", \"escape\": -0.02885914137003829, \"epitope\": \"epitope 1\", \"reference_site\": \"164\", \"functional effect\": -0.1064, \"times_seen\": 22.0}, {\"site\": 160, \"mutant\": \"D\", \"escape\": -0.023653025373285664, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.6996, \"times_seen\": 14.0}, {\"site\": 160, \"mutant\": \"H\", \"escape\": -0.0014731275513831545, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": 0.1748, \"times_seen\": 1.0}, {\"site\": 160, \"mutant\": \"I\", \"escape\": -0.029668736490884463, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.3027, \"times_seen\": 16.0}, {\"site\": 160, \"mutant\": \"K\", \"escape\": 0.00139895487813299, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.591, \"times_seen\": 5.0}, {\"site\": 160, \"mutant\": \"M\", \"escape\": -0.0481023576986694, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.311, \"times_seen\": 12.0}, {\"site\": 160, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 160, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.8719, \"times_seen\": null}, {\"site\": 160, \"mutant\": \"S\", \"escape\": -0.03353817732445024, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": 0.0485, \"times_seen\": 23.0}, {\"site\": 160, \"mutant\": \"Y\", \"escape\": -0.04439968651062885, \"epitope\": \"epitope 1\", \"reference_site\": \"165\", \"functional effect\": -0.5794, \"times_seen\": 10.0}, {\"site\": 161, \"mutant\": \"-\", \"escape\": 0.018059029426621444, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.8512, \"times_seen\": 3.0}, {\"site\": 161, \"mutant\": \"A\", \"escape\": -0.0034249701178697893, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.1822, \"times_seen\": 1.0}, {\"site\": 161, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"F\", \"escape\": -0.0027417878806770945, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.5685, \"times_seen\": 1.0}, {\"site\": 161, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -3.0134, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"R\", \"escape\": 0.0021320119553083165, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.8823, \"times_seen\": 2.0}, {\"site\": 161, \"mutant\": \"S\", \"escape\": -0.012190208182390014, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.9128, \"times_seen\": 6.0}, {\"site\": 161, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -3.0054, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"Y\", \"escape\": -0.0073590882235772224, \"epitope\": \"epitope 1\", \"reference_site\": \"166\", \"functional effect\": -2.5698, \"times_seen\": 5.0}, {\"site\": 162, \"mutant\": \"-\", \"escape\": -0.023076133778829694, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -1.1296, \"times_seen\": 11.0}, {\"site\": 162, \"mutant\": \"A\", \"escape\": -0.07212053570714401, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.2336, \"times_seen\": 8.0}, {\"site\": 162, \"mutant\": \"E\", \"escape\": -0.01412673318007663, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.4323, \"times_seen\": 7.0}, {\"site\": 162, \"mutant\": \"I\", \"escape\": -0.013975180970410915, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.6835, \"times_seen\": 45.0}, {\"site\": 162, \"mutant\": \"L\", \"escape\": 0.025938195707226937, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.708, \"times_seen\": 11.0}, {\"site\": 162, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.1392, \"times_seen\": null}, {\"site\": 162, \"mutant\": \"S\", \"escape\": -0.7888237445216782, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": 0.0177, \"times_seen\": 71.0}, {\"site\": 162, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 162, \"mutant\": \"V\", \"escape\": -0.2013493919671067, \"epitope\": \"epitope 1\", \"reference_site\": \"167\", \"functional effect\": -0.0554, \"times_seen\": 11.0}, {\"site\": 163, \"mutant\": \"-\", \"escape\": 0.05533863320416635, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.4392, \"times_seen\": 23.0}, {\"site\": 163, \"mutant\": \"A\", \"escape\": 0.48362325187800553, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.4464, \"times_seen\": 19.0}, {\"site\": 163, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.2547, \"times_seen\": null}, {\"site\": 163, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 163, \"mutant\": \"I\", \"escape\": 0.005481093528200053, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.3046, \"times_seen\": 5.0}, {\"site\": 163, \"mutant\": \"L\", \"escape\": -0.2270168207776321, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.0966, \"times_seen\": 62.0}, {\"site\": 163, \"mutant\": \"S\", \"escape\": 0.0718347450719431, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.5267, \"times_seen\": 9.0}, {\"site\": 163, \"mutant\": \"V\", \"escape\": 0.014655335187713179, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": 0.0364, \"times_seen\": 2.0}, {\"site\": 163, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"168\", \"functional effect\": -0.8997, \"times_seen\": null}, {\"site\": 164, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -3.0021, \"times_seen\": null}, {\"site\": 164, \"mutant\": \"-\", \"escape\": 0.0196433885004219, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -1.1936, \"times_seen\": 6.0}, {\"site\": 164, \"mutant\": \"D\", \"escape\": -0.04186774985371726, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": 0.0394, \"times_seen\": 29.0}, {\"site\": 164, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 164, \"mutant\": \"G\", \"escape\": 0.012025654588398483, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.515, \"times_seen\": 3.0}, {\"site\": 164, \"mutant\": \"K\", \"escape\": -0.12946718232044116, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.4174, \"times_seen\": 92.0}, {\"site\": 164, \"mutant\": \"N\", \"escape\": -0.033054165933257995, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": 0.0342, \"times_seen\": 19.0}, {\"site\": 164, \"mutant\": \"Q\", \"escape\": -0.04085266808932532, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.3936, \"times_seen\": 11.0}, {\"site\": 164, \"mutant\": \"V\", \"escape\": 0.009663811957644238, \"epitope\": \"epitope 1\", \"reference_site\": \"169\", \"functional effect\": -0.3211, \"times_seen\": 15.0}, {\"site\": 165, \"mutant\": \"*\", \"escape\": 0.003009554093479267, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -1.4378, \"times_seen\": 1.0}, {\"site\": 165, \"mutant\": \"-\", \"escape\": -0.0023178903460295765, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.3881, \"times_seen\": 16.0}, {\"site\": 165, \"mutant\": \"C\", \"escape\": -0.017416846188584745, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.7147, \"times_seen\": 14.0}, {\"site\": 165, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.3584, \"times_seen\": null}, {\"site\": 165, \"mutant\": \"F\", \"escape\": -0.011952866125015444, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.0061, \"times_seen\": 20.0}, {\"site\": 165, \"mutant\": \"H\", \"escape\": 0.12414925015065116, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.059, \"times_seen\": 60.0}, {\"site\": 165, \"mutant\": \"I\", \"escape\": -0.004827197838706455, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.2233, \"times_seen\": 7.0}, {\"site\": 165, \"mutant\": \"M\", \"escape\": 0.011360990573751728, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.1524, \"times_seen\": 7.0}, {\"site\": 165, \"mutant\": \"N\", \"escape\": 0.023691587629893717, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": -0.7647, \"times_seen\": 4.0}, {\"site\": 165, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"170\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 166, \"mutant\": \"-\", \"escape\": -0.044665134781937114, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.2477, \"times_seen\": 18.0}, {\"site\": 166, \"mutant\": \"A\", \"escape\": 0.02605903905579265, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.1624, \"times_seen\": 47.0}, {\"site\": 166, \"mutant\": \"C\", \"escape\": -0.008180077825007645, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.6295, \"times_seen\": 13.0}, {\"site\": 166, \"mutant\": \"E\", \"escape\": -0.012357880519728956, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0418, \"times_seen\": 4.0}, {\"site\": 166, \"mutant\": \"F\", \"escape\": -0.006790188260490208, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0087, \"times_seen\": 34.0}, {\"site\": 166, \"mutant\": \"I\", \"escape\": 0.03394015657025886, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0754, \"times_seen\": 48.0}, {\"site\": 166, \"mutant\": \"L\", \"escape\": 0.029171870657069686, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.14, \"times_seen\": 37.0}, {\"site\": 166, \"mutant\": \"M\", \"escape\": -0.00591696624421708, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.0036, \"times_seen\": 14.0}, {\"site\": 166, \"mutant\": \"S\", \"escape\": -0.00866829223756723, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": -0.1799, \"times_seen\": 5.0}, {\"site\": 166, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"171\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 167, \"mutant\": \"A\", \"escape\": -0.025636159657795917, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.0799, \"times_seen\": 6.0}, {\"site\": 167, \"mutant\": \"C\", \"escape\": -0.00336241026320867, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -1.1398, \"times_seen\": 1.0}, {\"site\": 167, \"mutant\": \"F\", \"escape\": -0.011541845224933995, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.1085, \"times_seen\": 28.0}, {\"site\": 167, \"mutant\": \"G\", \"escape\": -0.0036051283057146302, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.1978, \"times_seen\": 7.0}, {\"site\": 167, \"mutant\": \"I\", \"escape\": -0.004806469345628354, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.5557, \"times_seen\": 3.0}, {\"site\": 167, \"mutant\": \"L\", \"escape\": -0.11604358257225891, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.1065, \"times_seen\": 6.0}, {\"site\": 167, \"mutant\": \"N\", \"escape\": -0.04495862440458406, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.0688, \"times_seen\": 32.0}, {\"site\": 167, \"mutant\": \"R\", \"escape\": -0.009851934740982768, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.2875, \"times_seen\": 3.0}, {\"site\": 167, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 167, \"mutant\": \"T\", \"escape\": -0.01945647407599178, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.0488, \"times_seen\": 23.0}, {\"site\": 167, \"mutant\": \"Y\", \"escape\": 0.008284446082753527, \"epitope\": \"epitope 1\", \"reference_site\": \"172\", \"functional effect\": -0.3347, \"times_seen\": 14.0}, {\"site\": 168, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -1.0772, \"times_seen\": null}, {\"site\": 168, \"mutant\": \"D\", \"escape\": -0.010468525143830615, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -0.1765, \"times_seen\": 3.0}, {\"site\": 168, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.06, \"times_seen\": null}, {\"site\": 168, \"mutant\": \"H\", \"escape\": 0.002643693368379553, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0195, \"times_seen\": 29.0}, {\"site\": 168, \"mutant\": \"K\", \"escape\": -0.0008732795550941552, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -0.1131, \"times_seen\": 29.0}, {\"site\": 168, \"mutant\": \"L\", \"escape\": 0.02171920147000523, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0819, \"times_seen\": 10.0}, {\"site\": 168, \"mutant\": \"P\", \"escape\": 0.01736282757335401, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": -0.1616, \"times_seen\": 13.0}, {\"site\": 168, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 168, \"mutant\": \"R\", \"escape\": -0.5318274819580219, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.0184, \"times_seen\": 19.0}, {\"site\": 168, \"mutant\": \"S\", \"escape\": -0.006141224203184459, \"epitope\": \"epitope 1\", \"reference_site\": \"173\", \"functional effect\": 0.1903, \"times_seen\": 11.0}, {\"site\": 169, \"mutant\": \"A\", \"escape\": 0.23244243410407603, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.0202, \"times_seen\": 16.0}, {\"site\": 169, \"mutant\": \"H\", \"escape\": -0.07251810851338888, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.2334, \"times_seen\": 21.0}, {\"site\": 169, \"mutant\": \"L\", \"escape\": -0.020841274310054295, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.2764, \"times_seen\": 33.0}, {\"site\": 169, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 169, \"mutant\": \"Q\", \"escape\": 0.0004935048086224651, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.4791, \"times_seen\": 5.0}, {\"site\": 169, \"mutant\": \"R\", \"escape\": 0.012162265119667448, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": -0.2852, \"times_seen\": 6.0}, {\"site\": 169, \"mutant\": \"S\", \"escape\": -0.02856099845492097, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": 0.1185, \"times_seen\": 39.0}, {\"site\": 169, \"mutant\": \"T\", \"escape\": 0.09742668875279581, \"epitope\": \"epitope 1\", \"reference_site\": \"174\", \"functional effect\": 0.0123, \"times_seen\": 35.0}, {\"site\": 170, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 170, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 170, \"mutant\": \"H\", \"escape\": -0.005134473189407653, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.2269, \"times_seen\": 1.0}, {\"site\": 170, \"mutant\": \"I\", \"escape\": -0.02469880559987375, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.0932, \"times_seen\": 22.0}, {\"site\": 170, \"mutant\": \"L\", \"escape\": -0.027419157706544267, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": -0.0807, \"times_seen\": 30.0}, {\"site\": 170, \"mutant\": \"S\", \"escape\": 0.007160927546161491, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": -0.1024, \"times_seen\": 26.0}, {\"site\": 170, \"mutant\": \"V\", \"escape\": -0.015657409811917582, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": 0.1541, \"times_seen\": 5.0}, {\"site\": 170, \"mutant\": \"Y\", \"escape\": -0.01110032843529641, \"epitope\": \"epitope 1\", \"reference_site\": \"175\", \"functional effect\": -0.6476, \"times_seen\": 3.0}, {\"site\": 171, \"mutant\": \"*\", \"escape\": -0.01669277794716033, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -2.6513, \"times_seen\": 6.0}, {\"site\": 171, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.5502, \"times_seen\": null}, {\"site\": 171, \"mutant\": \"A\", \"escape\": 0.24688530449371357, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.075, \"times_seen\": 88.0}, {\"site\": 171, \"mutant\": \"C\", \"escape\": -0.8888561179605855, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.175, \"times_seen\": 42.0}, {\"site\": 171, \"mutant\": \"D\", \"escape\": -0.029762650240680172, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.2332, \"times_seen\": 24.0}, {\"site\": 171, \"mutant\": \"E\", \"escape\": -0.012437452275642729, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0566, \"times_seen\": 40.0}, {\"site\": 171, \"mutant\": \"F\", \"escape\": 0.5860786310182056, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0043, \"times_seen\": 75.0}, {\"site\": 171, \"mutant\": \"G\", \"escape\": -0.09083072089565683, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0638, \"times_seen\": 64.0}, {\"site\": 171, \"mutant\": \"H\", \"escape\": 0.08072409555980595, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0169, \"times_seen\": 66.0}, {\"site\": 171, \"mutant\": \"I\", \"escape\": -0.11349826629663588, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0243, \"times_seen\": 48.0}, {\"site\": 171, \"mutant\": \"K\", \"escape\": 0.39410499899540574, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.3255, \"times_seen\": 60.0}, {\"site\": 171, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 171, \"mutant\": \"M\", \"escape\": -0.9510285215306222, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0666, \"times_seen\": 68.0}, {\"site\": 171, \"mutant\": \"N\", \"escape\": 0.0004666791023843453, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0796, \"times_seen\": 29.0}, {\"site\": 171, \"mutant\": \"P\", \"escape\": -0.04623219418084356, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.1479, \"times_seen\": 181.0}, {\"site\": 171, \"mutant\": \"Q\", \"escape\": 0.01350497064692733, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.1346, \"times_seen\": 95.0}, {\"site\": 171, \"mutant\": \"R\", \"escape\": 0.03478554725233051, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.2682, \"times_seen\": 142.0}, {\"site\": 171, \"mutant\": \"S\", \"escape\": 0.15763489935877184, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0793, \"times_seen\": 132.0}, {\"site\": 171, \"mutant\": \"T\", \"escape\": -0.5243244229296254, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0044, \"times_seen\": 94.0}, {\"site\": 171, \"mutant\": \"V\", \"escape\": 0.01335212927714135, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0387, \"times_seen\": 106.0}, {\"site\": 171, \"mutant\": \"W\", \"escape\": -0.08021598934906084, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": 0.0425, \"times_seen\": 31.0}, {\"site\": 171, \"mutant\": \"Y\", \"escape\": -0.019390109734920523, \"epitope\": \"epitope 1\", \"reference_site\": \"176\", \"functional effect\": -0.0488, \"times_seen\": 34.0}, {\"site\": 172, \"mutant\": \"I\", \"escape\": 0.3074994492195893, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0731, \"times_seen\": 130.0}, {\"site\": 172, \"mutant\": \"K\", \"escape\": 0.16828422240219418, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0748, \"times_seen\": 121.0}, {\"site\": 172, \"mutant\": \"L\", \"escape\": -0.0297586419679929, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": -0.0551, \"times_seen\": 39.0}, {\"site\": 172, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 172, \"mutant\": \"N\", \"escape\": 0.013326282784267198, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 172, \"mutant\": \"R\", \"escape\": -0.029738708096413564, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.0645, \"times_seen\": 12.0}, {\"site\": 172, \"mutant\": \"T\", \"escape\": 0.06518852359840759, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": -0.0037, \"times_seen\": 38.0}, {\"site\": 172, \"mutant\": \"V\", \"escape\": -0.082492427202336, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": -0.0063, \"times_seen\": 46.0}, {\"site\": 172, \"mutant\": \"W\", \"escape\": 0.002286335551202654, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.1881, \"times_seen\": 13.0}, {\"site\": 172, \"mutant\": \"Y\", \"escape\": 0.028910545852057174, \"epitope\": \"epitope 1\", \"reference_site\": \"177\", \"functional effect\": 0.1976, \"times_seen\": 19.0}, {\"site\": 173, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -2.3457, \"times_seen\": null}, {\"site\": 173, \"mutant\": \"A\", \"escape\": -0.00735106240805993, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0751, \"times_seen\": 100.0}, {\"site\": 173, \"mutant\": \"C\", \"escape\": -0.017367992272606977, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.359, \"times_seen\": 40.0}, {\"site\": 173, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 173, \"mutant\": \"E\", \"escape\": 0.021110028388790204, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0638, \"times_seen\": 47.0}, {\"site\": 173, \"mutant\": \"F\", \"escape\": -0.07273181521073951, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2507, \"times_seen\": 48.0}, {\"site\": 173, \"mutant\": \"G\", \"escape\": -0.15387403070775624, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0331, \"times_seen\": 128.0}, {\"site\": 173, \"mutant\": \"H\", \"escape\": 0.2937200681723785, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0807, \"times_seen\": 106.0}, {\"site\": 173, \"mutant\": \"I\", \"escape\": 0.3114566397024926, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2644, \"times_seen\": 32.0}, {\"site\": 173, \"mutant\": \"K\", \"escape\": -0.007082070704612155, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": 0.1292, \"times_seen\": 27.0}, {\"site\": 173, \"mutant\": \"L\", \"escape\": 0.6522615481370566, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2273, \"times_seen\": 61.0}, {\"site\": 173, \"mutant\": \"M\", \"escape\": -0.016127520608560954, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.4233, \"times_seen\": 20.0}, {\"site\": 173, \"mutant\": \"N\", \"escape\": -0.2628494516290442, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0223, \"times_seen\": 168.0}, {\"site\": 173, \"mutant\": \"P\", \"escape\": -0.04703004933770265, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.1434, \"times_seen\": 44.0}, {\"site\": 173, \"mutant\": \"Q\", \"escape\": 0.055243169252660485, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0238, \"times_seen\": 20.0}, {\"site\": 173, \"mutant\": \"R\", \"escape\": -0.0017731888456931578, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.1216, \"times_seen\": 68.0}, {\"site\": 173, \"mutant\": \"S\", \"escape\": -0.7035060432774437, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0435, \"times_seen\": 115.0}, {\"site\": 173, \"mutant\": \"T\", \"escape\": -0.09703765578713792, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.0833, \"times_seen\": 105.0}, {\"site\": 173, \"mutant\": \"V\", \"escape\": -0.07551269090724352, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2056, \"times_seen\": 80.0}, {\"site\": 173, \"mutant\": \"W\", \"escape\": -0.024399058797316648, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.3205, \"times_seen\": 13.0}, {\"site\": 173, \"mutant\": \"Y\", \"escape\": -0.11814211878766548, \"epitope\": \"epitope 1\", \"reference_site\": \"178\", \"functional effect\": -0.2031, \"times_seen\": 137.0}, {\"site\": 174, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -3.2847, \"times_seen\": null}, {\"site\": 174, \"mutant\": \"F\", \"escape\": -0.07139184323666535, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.1159, \"times_seen\": 80.0}, {\"site\": 174, \"mutant\": \"I\", \"escape\": 0.0663405254337386, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 174, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 174, \"mutant\": \"M\", \"escape\": 0.0025191019068895697, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.1622, \"times_seen\": 3.0}, {\"site\": 174, \"mutant\": \"P\", \"escape\": 0.0023361332772559693, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.2061, \"times_seen\": 27.0}, {\"site\": 174, \"mutant\": \"R\", \"escape\": -0.16866638101889853, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.1583, \"times_seen\": 13.0}, {\"site\": 174, \"mutant\": \"S\", \"escape\": -0.048749433899443126, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.0705, \"times_seen\": 32.0}, {\"site\": 174, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": 0.3709, \"times_seen\": null}, {\"site\": 174, \"mutant\": \"W\", \"escape\": 0.017345162701331292, \"epitope\": \"epitope 1\", \"reference_site\": \"179\", \"functional effect\": -0.2258, \"times_seen\": 1.0}, {\"site\": 175, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -2.3131, \"times_seen\": null}, {\"site\": 175, \"mutant\": \"A\", \"escape\": -0.3658042957006771, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.1565, \"times_seen\": 22.0}, {\"site\": 175, \"mutant\": \"D\", \"escape\": -0.007005954149708412, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.0057, \"times_seen\": 60.0}, {\"site\": 175, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 175, \"mutant\": \"G\", \"escape\": -0.0477086262617205, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.0243, \"times_seen\": 83.0}, {\"site\": 175, \"mutant\": \"K\", \"escape\": 0.029618625625222758, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": 0.0545, \"times_seen\": 62.0}, {\"site\": 175, \"mutant\": \"Q\", \"escape\": -0.0036467072319800683, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.2727, \"times_seen\": 8.0}, {\"site\": 175, \"mutant\": \"R\", \"escape\": -1.38250156251128, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": 0.0304, \"times_seen\": 13.0}, {\"site\": 175, \"mutant\": \"V\", \"escape\": -0.026160424626183586, \"epitope\": \"epitope 1\", \"reference_site\": \"180\", \"functional effect\": -0.137, \"times_seen\": 50.0}, {\"site\": 176, \"mutant\": \"-\", \"escape\": 0.006689064159062117, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0869, \"times_seen\": 1.0}, {\"site\": 176, \"mutant\": \"A\", \"escape\": -0.07684491600176349, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0627, \"times_seen\": 47.0}, {\"site\": 176, \"mutant\": \"C\", \"escape\": 0.03496739316397822, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0515, \"times_seen\": 4.0}, {\"site\": 176, \"mutant\": \"D\", \"escape\": -0.12482881115195335, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0625, \"times_seen\": 42.0}, {\"site\": 176, \"mutant\": \"E\", \"escape\": 0.29525689650282505, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0764, \"times_seen\": 47.0}, {\"site\": 176, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 176, \"mutant\": \"L\", \"escape\": -0.002353272607479938, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": -0.2688, \"times_seen\": 14.0}, {\"site\": 176, \"mutant\": \"R\", \"escape\": -0.12243002604273259, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": -0.0258, \"times_seen\": 36.0}, {\"site\": 176, \"mutant\": \"S\", \"escape\": 0.016601490498256894, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.0761, \"times_seen\": 22.0}, {\"site\": 176, \"mutant\": \"V\", \"escape\": 0.08980878519168313, \"epitope\": \"epitope 1\", \"reference_site\": \"181\", \"functional effect\": 0.016, \"times_seen\": 37.0}, {\"site\": 177, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -3.2884, \"times_seen\": null}, {\"site\": 177, \"mutant\": \"-\", \"escape\": 0.004911031116752674, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 177, \"mutant\": \"E\", \"escape\": -0.018915482051987117, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0575, \"times_seen\": 104.0}, {\"site\": 177, \"mutant\": \"I\", \"escape\": 0.09082851272794422, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0654, \"times_seen\": 15.0}, {\"site\": 177, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 177, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -0.3944, \"times_seen\": null}, {\"site\": 177, \"mutant\": \"N\", \"escape\": -0.0666385163136496, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0764, \"times_seen\": 131.0}, {\"site\": 177, \"mutant\": \"Q\", \"escape\": -0.01842579173514432, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": -0.0279, \"times_seen\": 17.0}, {\"site\": 177, \"mutant\": \"R\", \"escape\": -0.3734729934500007, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.0177, \"times_seen\": 116.0}, {\"site\": 177, \"mutant\": \"T\", \"escape\": -0.015557649240999108, \"epitope\": \"epitope 1\", \"reference_site\": \"182\", \"functional effect\": 0.2054, \"times_seen\": 22.0}, {\"site\": 178, \"mutant\": \"*\", \"escape\": -0.004516516751106245, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -2.6882, \"times_seen\": 5.0}, {\"site\": 178, \"mutant\": \"-\", \"escape\": 0.004267986521410621, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 178, \"mutant\": \"E\", \"escape\": -0.9703589852240837, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.1254, \"times_seen\": 23.0}, {\"site\": 178, \"mutant\": \"H\", \"escape\": 0.06087752589398732, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -0.0332, \"times_seen\": 102.0}, {\"site\": 178, \"mutant\": \"K\", \"escape\": 0.009796991923160537, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0011, \"times_seen\": 13.0}, {\"site\": 178, \"mutant\": \"L\", \"escape\": -0.18300345342404317, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0052, \"times_seen\": 74.0}, {\"site\": 178, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 178, \"mutant\": \"P\", \"escape\": 0.0042371949823395, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": -0.4437, \"times_seen\": 8.0}, {\"site\": 178, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 178, \"mutant\": \"R\", \"escape\": -0.02372479721683298, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0312, \"times_seen\": 51.0}, {\"site\": 178, \"mutant\": \"T\", \"escape\": 0.02110526104477069, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.1608, \"times_seen\": 6.0}, {\"site\": 178, \"mutant\": \"Y\", \"escape\": 0.014827792117750581, \"epitope\": \"epitope 1\", \"reference_site\": \"183\", \"functional effect\": 0.0808, \"times_seen\": 3.0}, {\"site\": 179, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 179, \"mutant\": \"A\", \"escape\": -0.013147805208332959, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.1384, \"times_seen\": 15.0}, {\"site\": 179, \"mutant\": \"C\", \"escape\": 0.02767081917539738, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 179, \"mutant\": \"D\", \"escape\": 0.004968646556536895, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0672, \"times_seen\": 133.0}, {\"site\": 179, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 179, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.2267, \"times_seen\": null}, {\"site\": 179, \"mutant\": \"S\", \"escape\": -0.02197020580820283, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0312, \"times_seen\": 76.0}, {\"site\": 179, \"mutant\": \"V\", \"escape\": -0.012852770530241043, \"epitope\": \"epitope 1\", \"reference_site\": \"184\", \"functional effect\": 0.0414, \"times_seen\": 49.0}, {\"site\": 180, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 180, \"mutant\": \"D\", \"escape\": 0.02563929473673588, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0329, \"times_seen\": 49.0}, {\"site\": 180, \"mutant\": \"I\", \"escape\": -0.13810330950844282, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0399, \"times_seen\": 38.0}, {\"site\": 180, \"mutant\": \"K\", \"escape\": -0.014463055969894549, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": -0.0217, \"times_seen\": 24.0}, {\"site\": 180, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 180, \"mutant\": \"S\", \"escape\": -0.04779320324094043, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": -0.0815, \"times_seen\": 66.0}, {\"site\": 180, \"mutant\": \"T\", \"escape\": 0.021503771383841096, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.027, \"times_seen\": 16.0}, {\"site\": 180, \"mutant\": \"Y\", \"escape\": -0.034019970935093374, \"epitope\": \"epitope 1\", \"reference_site\": \"185\", \"functional effect\": 0.0688, \"times_seen\": 28.0}, {\"site\": 181, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 181, \"mutant\": \"C\", \"escape\": -0.003181603661410313, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.1598, \"times_seen\": 1.0}, {\"site\": 181, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 181, \"mutant\": \"I\", \"escape\": 0.006239479456565996, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0153, \"times_seen\": 24.0}, {\"site\": 181, \"mutant\": \"L\", \"escape\": 0.04758415568679119, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0256, \"times_seen\": 44.0}, {\"site\": 181, \"mutant\": \"S\", \"escape\": 0.03228208634020002, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0144, \"times_seen\": 46.0}, {\"site\": 181, \"mutant\": \"V\", \"escape\": -0.016127704617938034, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": -0.0381, \"times_seen\": 13.0}, {\"site\": 181, \"mutant\": \"Y\", \"escape\": -0.005170556822745838, \"epitope\": \"epitope 1\", \"reference_site\": \"186\", \"functional effect\": 0.0674, \"times_seen\": 2.0}, {\"site\": 182, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 182, \"mutant\": \"E\", \"escape\": 0.372010090382867, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.0127, \"times_seen\": 50.0}, {\"site\": 182, \"mutant\": \"I\", \"escape\": 0.0348400763973723, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.1137, \"times_seen\": 18.0}, {\"site\": 182, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 182, \"mutant\": \"M\", \"escape\": 0.0014283969032711883, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.3116, \"times_seen\": 2.0}, {\"site\": 182, \"mutant\": \"N\", \"escape\": -0.002536656263841509, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.1255, \"times_seen\": 27.0}, {\"site\": 182, \"mutant\": \"Q\", \"escape\": 0.00514949412870075, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": 0.1238, \"times_seen\": 22.0}, {\"site\": 182, \"mutant\": \"R\", \"escape\": 0.6010828883088133, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": -0.0472, \"times_seen\": 36.0}, {\"site\": 182, \"mutant\": \"T\", \"escape\": 0.007173004898452015, \"epitope\": \"epitope 1\", \"reference_site\": \"187\", \"functional effect\": -0.0964, \"times_seen\": 3.0}, {\"site\": 183, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 183, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 183, \"mutant\": \"D\", \"escape\": -0.014466230344346765, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": -0.1389, \"times_seen\": 15.0}, {\"site\": 183, \"mutant\": \"I\", \"escape\": 0.0260650461485554, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.0499, \"times_seen\": 9.0}, {\"site\": 183, \"mutant\": \"K\", \"escape\": 0.040925606069821416, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.012, \"times_seen\": 18.0}, {\"site\": 183, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 183, \"mutant\": \"S\", \"escape\": -0.044352294515297576, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.1074, \"times_seen\": 73.0}, {\"site\": 183, \"mutant\": \"T\", \"escape\": 0.023751455501613016, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.2032, \"times_seen\": 18.0}, {\"site\": 183, \"mutant\": \"Y\", \"escape\": -0.08447463284800985, \"epitope\": \"epitope 1\", \"reference_site\": \"188\", \"functional effect\": 0.0384, \"times_seen\": 62.0}, {\"site\": 184, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 184, \"mutant\": \"F\", \"escape\": -0.022557927316706458, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.1499, \"times_seen\": 25.0}, {\"site\": 184, \"mutant\": \"I\", \"escape\": -0.013589522484998636, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.1391, \"times_seen\": 11.0}, {\"site\": 184, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 184, \"mutant\": \"M\", \"escape\": -0.009817444077691926, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.143, \"times_seen\": 3.0}, {\"site\": 184, \"mutant\": \"P\", \"escape\": -0.011665071084765609, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -2.8453, \"times_seen\": 5.0}, {\"site\": 184, \"mutant\": \"Q\", \"escape\": -0.0006384344559922537, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 184, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 184, \"mutant\": \"S\", \"escape\": -0.003789497892400715, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -0.9961, \"times_seen\": 1.0}, {\"site\": 184, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"189\", \"functional effect\": -0.8023, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"G\", \"escape\": -0.02565418793728309, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.0488, \"times_seen\": 25.0}, {\"site\": 185, \"mutant\": \"I\", \"escape\": 0.027994299121787053, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.184, \"times_seen\": 4.0}, {\"site\": 185, \"mutant\": \"K\", \"escape\": -0.011172973464441854, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.0704, \"times_seen\": 28.0}, {\"site\": 185, \"mutant\": \"M\", \"escape\": 0.09560046994641959, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.2213, \"times_seen\": 35.0}, {\"site\": 185, \"mutant\": \"N\", \"escape\": 0.009258356419684026, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.0191, \"times_seen\": 8.0}, {\"site\": 185, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"S\", \"escape\": 0.10673167716688117, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": -0.0367, \"times_seen\": 42.0}, {\"site\": 185, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"W\", \"escape\": -0.002865262742422451, \"epitope\": \"epitope 1\", \"reference_site\": \"190\", \"functional effect\": 0.0793, \"times_seen\": 17.0}, {\"site\": 186, \"mutant\": \"*\", \"escape\": 0.00016857229487560882, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -1.3138, \"times_seen\": 1.0}, {\"site\": 186, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 186, \"mutant\": \"D\", \"escape\": -0.0019919395749228804, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -2.6406, \"times_seen\": 1.0}, {\"site\": 186, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 186, \"mutant\": \"G\", \"escape\": 0.020393351960696155, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -2.9466, \"times_seen\": 4.0}, {\"site\": 186, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -2.487, \"times_seen\": null}, {\"site\": 186, \"mutant\": \"N\", \"escape\": -0.0033062665625903155, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -1.0278, \"times_seen\": 1.0}, {\"site\": 186, \"mutant\": \"Q\", \"escape\": -0.0063644047884915496, \"epitope\": \"epitope 1\", \"reference_site\": \"191\", \"functional effect\": -1.948, \"times_seen\": 4.0}, {\"site\": 187, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 187, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.7, \"times_seen\": null}, {\"site\": 187, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 187, \"mutant\": \"I\", \"escape\": 0.014804215471647762, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.3386, \"times_seen\": 4.0}, {\"site\": 187, \"mutant\": \"L\", \"escape\": -0.06652814802600361, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.2058, \"times_seen\": 24.0}, {\"site\": 187, \"mutant\": \"S\", \"escape\": -0.007516982940901414, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.8613, \"times_seen\": 2.0}, {\"site\": 187, \"mutant\": \"Y\", \"escape\": 0.011447874633292178, \"epitope\": \"epitope 1\", \"reference_site\": \"192\", \"functional effect\": -0.2117, \"times_seen\": 12.0}, {\"site\": 188, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 188, \"mutant\": \"A\", \"escape\": -0.004693761567667054, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": 0.1895, \"times_seen\": 1.0}, {\"site\": 188, \"mutant\": \"C\", \"escape\": -0.007338189150933742, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -0.3795, \"times_seen\": 12.0}, {\"site\": 188, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -3.0012, \"times_seen\": null}, {\"site\": 188, \"mutant\": \"L\", \"escape\": -0.06534201588962264, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": 0.1124, \"times_seen\": 43.0}, {\"site\": 188, \"mutant\": \"M\", \"escape\": -0.03448989658591575, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -0.4666, \"times_seen\": 15.0}, {\"site\": 188, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": -1.0815, \"times_seen\": null}, {\"site\": 188, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"193\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"I\", \"escape\": -0.004926605347197734, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.6875, \"times_seen\": 3.0}, {\"site\": 189, \"mutant\": \"L\", \"escape\": -0.01646015235590795, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.1861, \"times_seen\": 7.0}, {\"site\": 189, \"mutant\": \"M\", \"escape\": 0.0005115155011249458, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -1.0215, \"times_seen\": 1.0}, {\"site\": 189, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -2.9593, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"V\", \"escape\": -0.03633827775460617, \"epitope\": \"epitope 1\", \"reference_site\": \"194\", \"functional effect\": -0.537, \"times_seen\": 6.0}, {\"site\": 190, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"M\", \"escape\": -0.008247522790706025, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 190, \"mutant\": \"N\", \"escape\": -0.0152643285167313, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -1.997, \"times_seen\": 3.0}, {\"site\": 190, \"mutant\": \"R\", \"escape\": -0.25459126577595714, \"epitope\": \"epitope 1\", \"reference_site\": \"195\", \"functional effect\": -0.7651, \"times_seen\": 42.0}, {\"site\": 191, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 191, \"mutant\": \"D\", \"escape\": -0.004827005120429699, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": -0.2374, \"times_seen\": 1.0}, {\"site\": 191, \"mutant\": \"E\", \"escape\": 0.011965814659934227, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.2717, \"times_seen\": 7.0}, {\"site\": 191, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 191, \"mutant\": \"I\", \"escape\": -0.024932373136500742, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.3306, \"times_seen\": 16.0}, {\"site\": 191, \"mutant\": \"K\", \"escape\": -0.012767405820237996, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": -0.752, \"times_seen\": 4.0}, {\"site\": 191, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 191, \"mutant\": \"S\", \"escape\": -0.0004217018934127149, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.249, \"times_seen\": 9.0}, {\"site\": 191, \"mutant\": \"Y\", \"escape\": -0.025238178420913793, \"epitope\": \"epitope 1\", \"reference_site\": \"196\", \"functional effect\": 0.3514, \"times_seen\": 10.0}, {\"site\": 192, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 192, \"mutant\": \"L\", \"escape\": 0.01344909237728699, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.4293, \"times_seen\": 14.0}, {\"site\": 192, \"mutant\": \"M\", \"escape\": -0.016198704947745304, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.0857, \"times_seen\": 11.0}, {\"site\": 192, \"mutant\": \"N\", \"escape\": 0.005530503411852225, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": 0.1366, \"times_seen\": 2.0}, {\"site\": 192, \"mutant\": \"S\", \"escape\": -1.1229246732980249e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.33, \"times_seen\": 9.0}, {\"site\": 192, \"mutant\": \"T\", \"escape\": 0.0066282375701498895, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.0423, \"times_seen\": 34.0}, {\"site\": 192, \"mutant\": \"V\", \"escape\": 0.02511443377310872, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.1628, \"times_seen\": 19.0}, {\"site\": 192, \"mutant\": \"Y\", \"escape\": 0.004146608972896242, \"epitope\": \"epitope 1\", \"reference_site\": \"197\", \"functional effect\": -0.0628, \"times_seen\": 7.0}, {\"site\": 193, \"mutant\": \"A\", \"escape\": 0.00962295491434352, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.1032, \"times_seen\": 14.0}, {\"site\": 193, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 193, \"mutant\": \"E\", \"escape\": 0.3229202385113755, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.3554, \"times_seen\": 10.0}, {\"site\": 193, \"mutant\": \"G\", \"escape\": 0.06844384659081602, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.0112, \"times_seen\": 29.0}, {\"site\": 193, \"mutant\": \"H\", \"escape\": 0.006855577784019824, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.041, \"times_seen\": 24.0}, {\"site\": 193, \"mutant\": \"M\", \"escape\": -0.0047450100576239915, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.0024, \"times_seen\": 16.0}, {\"site\": 193, \"mutant\": \"N\", \"escape\": -0.07939780877283445, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": 0.3645, \"times_seen\": 14.0}, {\"site\": 193, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -2.9276, \"times_seen\": null}, {\"site\": 193, \"mutant\": \"Y\", \"escape\": 0.009727038693472283, \"epitope\": \"epitope 1\", \"reference_site\": \"198\", \"functional effect\": -0.081, \"times_seen\": 14.0}, {\"site\": 194, \"mutant\": \"A\", \"escape\": -0.03898601140569759, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.2591, \"times_seen\": 11.0}, {\"site\": 194, \"mutant\": \"C\", \"escape\": -0.031292467818794016, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -1.1385, \"times_seen\": 43.0}, {\"site\": 194, \"mutant\": \"D\", \"escape\": 0.0183258618783155, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.8634, \"times_seen\": 41.0}, {\"site\": 194, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 194, \"mutant\": \"R\", \"escape\": -0.05276473055840795, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.7793, \"times_seen\": 9.0}, {\"site\": 194, \"mutant\": \"S\", \"escape\": -0.04320588116344519, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.2356, \"times_seen\": 23.0}, {\"site\": 194, \"mutant\": \"V\", \"escape\": -0.05160507724426308, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.9871, \"times_seen\": 33.0}, {\"site\": 194, \"mutant\": \"W\", \"escape\": -0.003360724372957255, \"epitope\": \"epitope 1\", \"reference_site\": \"199\", \"functional effect\": -0.2722, \"times_seen\": 4.0}, {\"site\": 195, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": -2.8839, \"times_seen\": null}, {\"site\": 195, \"mutant\": \"C\", \"escape\": -0.004197025281688652, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.2463, \"times_seen\": 39.0}, {\"site\": 195, \"mutant\": \"D\", \"escape\": 0.002697246740096951, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 195, \"mutant\": \"F\", \"escape\": 0.005487934197414675, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4444, \"times_seen\": 13.0}, {\"site\": 195, \"mutant\": \"H\", \"escape\": 0.440608598002613, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.1067, \"times_seen\": 58.0}, {\"site\": 195, \"mutant\": \"I\", \"escape\": -0.0586665699193968, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 195, \"mutant\": \"L\", \"escape\": -0.0237066235149395, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.338, \"times_seen\": 8.0}, {\"site\": 195, \"mutant\": \"N\", \"escape\": -0.0053753447062440275, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.0289, \"times_seen\": 6.0}, {\"site\": 195, \"mutant\": \"Q\", \"escape\": -0.0012264929627047066, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 195, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"200\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 196, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 196, \"mutant\": \"I\", \"escape\": -0.0030566871488695623, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.1425, \"times_seen\": 1.0}, {\"site\": 196, \"mutant\": \"L\", \"escape\": -0.03025499507680419, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.3392, \"times_seen\": 14.0}, {\"site\": 196, \"mutant\": \"S\", \"escape\": -0.011922575404792848, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": -1.9717, \"times_seen\": 3.0}, {\"site\": 196, \"mutant\": \"V\", \"escape\": 0.009608989130732465, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": 0.255, \"times_seen\": 1.0}, {\"site\": 196, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"201\", \"functional effect\": -0.6135, \"times_seen\": null}, {\"site\": 197, \"mutant\": \"E\", \"escape\": 0.002350043436272217, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.5772, \"times_seen\": 8.0}, {\"site\": 197, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.5056, \"times_seen\": null}, {\"site\": 197, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 197, \"mutant\": \"M\", \"escape\": -0.014138040272680667, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.2777, \"times_seen\": 4.0}, {\"site\": 197, \"mutant\": \"N\", \"escape\": -0.025683777250991052, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": -0.3112, \"times_seen\": 29.0}, {\"site\": 197, \"mutant\": \"R\", \"escape\": -1.301273271072775, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": 0.0764, \"times_seen\": 49.0}, {\"site\": 197, \"mutant\": \"T\", \"escape\": -0.029249098396187084, \"epitope\": \"epitope 1\", \"reference_site\": \"202\", \"functional effect\": 0.0004, \"times_seen\": 6.0}, {\"site\": 198, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 198, \"mutant\": \"L\", \"escape\": 0.03503496818635774, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.2275, \"times_seen\": 46.0}, {\"site\": 198, \"mutant\": \"M\", \"escape\": 0.03130618227863987, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.3953, \"times_seen\": 67.0}, {\"site\": 198, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 198, \"mutant\": \"T\", \"escape\": -0.052364545180077215, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.445, \"times_seen\": 20.0}, {\"site\": 198, \"mutant\": \"V\", \"escape\": -0.10517490425933028, \"epitope\": \"epitope 1\", \"reference_site\": \"203\", \"functional effect\": -0.0588, \"times_seen\": 58.0}, {\"site\": 199, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -2.2239, \"times_seen\": null}, {\"site\": 199, \"mutant\": \"C\", \"escape\": 0.00060492044766748, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -0.7565, \"times_seen\": 17.0}, {\"site\": 199, \"mutant\": \"F\", \"escape\": -0.3335950803467243, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -0.0822, \"times_seen\": 41.0}, {\"site\": 199, \"mutant\": \"H\", \"escape\": 0.10961155680491222, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": -0.164, \"times_seen\": 65.0}, {\"site\": 199, \"mutant\": \"L\", \"escape\": 0.9064796952559622, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": 0.0432, \"times_seen\": 13.0}, {\"site\": 199, \"mutant\": \"N\", \"escape\": 0.0019922190005924965, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": 0.1136, \"times_seen\": 1.0}, {\"site\": 199, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"204\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 200, \"mutant\": \"A\", \"escape\": -0.02356068105154208, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0281, \"times_seen\": 10.0}, {\"site\": 200, \"mutant\": \"C\", \"escape\": -0.008285792442413297, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.0198, \"times_seen\": 3.0}, {\"site\": 200, \"mutant\": \"F\", \"escape\": -0.14087887315131634, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.1648, \"times_seen\": 49.0}, {\"site\": 200, \"mutant\": \"G\", \"escape\": -0.0742776783456221, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.2185, \"times_seen\": 26.0}, {\"site\": 200, \"mutant\": \"I\", \"escape\": 0.329708837168679, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0784, \"times_seen\": 31.0}, {\"site\": 200, \"mutant\": \"N\", \"escape\": -0.0421786654262523, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.0072, \"times_seen\": 19.0}, {\"site\": 200, \"mutant\": \"R\", \"escape\": -0.005730669529523265, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0049, \"times_seen\": 5.0}, {\"site\": 200, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 200, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": -0.681, \"times_seen\": null}, {\"site\": 200, \"mutant\": \"Y\", \"escape\": -0.029895259167501968, \"epitope\": \"epitope 1\", \"reference_site\": \"205\", \"functional effect\": 0.0358, \"times_seen\": 16.0}, {\"site\": 201, \"mutant\": \"A\", \"escape\": 0.05931302654932029, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.1606, \"times_seen\": 6.0}, {\"site\": 201, \"mutant\": \"E\", \"escape\": 0.01842301557192969, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.6104, \"times_seen\": 9.0}, {\"site\": 201, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 201, \"mutant\": \"I\", \"escape\": -0.0032428293552999696, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": 0.1011, \"times_seen\": 1.0}, {\"site\": 201, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 201, \"mutant\": \"L\", \"escape\": -0.017952299420693534, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.0949, \"times_seen\": 8.0}, {\"site\": 201, \"mutant\": \"M\", \"escape\": 0.0168877990627763, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.6998, \"times_seen\": 10.0}, {\"site\": 201, \"mutant\": \"N\", \"escape\": -0.0029317839488414944, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.9007, \"times_seen\": 9.0}, {\"site\": 201, \"mutant\": \"R\", \"escape\": 0.05363056887041168, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.2913, \"times_seen\": 27.0}, {\"site\": 201, \"mutant\": \"T\", \"escape\": -0.01272743801071026, \"epitope\": \"epitope 1\", \"reference_site\": \"206\", \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 202, \"mutant\": \"D\", \"escape\": -0.0017469643029428517, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 202, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 202, \"mutant\": \"L\", \"escape\": 0.0010820856949799815, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0465, \"times_seen\": 10.0}, {\"site\": 202, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.3132, \"times_seen\": null}, {\"site\": 202, \"mutant\": \"N\", \"escape\": -0.002526511030365567, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0726, \"times_seen\": 19.0}, {\"site\": 202, \"mutant\": \"Q\", \"escape\": -0.04103595156516871, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0033, \"times_seen\": 12.0}, {\"site\": 202, \"mutant\": \"R\", \"escape\": 0.07289974780270077, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": 0.0603, \"times_seen\": 25.0}, {\"site\": 202, \"mutant\": \"S\", \"escape\": 0.00878412188548183, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.1124, \"times_seen\": 6.0}, {\"site\": 202, \"mutant\": \"Y\", \"escape\": -0.019519212335609142, \"epitope\": \"epitope 1\", \"reference_site\": \"207\", \"functional effect\": -0.0474, \"times_seen\": 70.0}, {\"site\": 203, \"mutant\": \"A\", \"escape\": -0.053975126616242305, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0387, \"times_seen\": 44.0}, {\"site\": 203, \"mutant\": \"I\", \"escape\": -0.07066303122378904, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0312, \"times_seen\": 41.0}, {\"site\": 203, \"mutant\": \"K\", \"escape\": -0.009266600937867554, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.1878, \"times_seen\": 17.0}, {\"site\": 203, \"mutant\": \"L\", \"escape\": -0.005335190021532453, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0927, \"times_seen\": 6.0}, {\"site\": 203, \"mutant\": \"M\", \"escape\": 0.057122111331785116, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.0399, \"times_seen\": 38.0}, {\"site\": 203, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.2688, \"times_seen\": null}, {\"site\": 203, \"mutant\": \"S\", \"escape\": 0.0156910636352545, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": -0.2993, \"times_seen\": 11.0}, {\"site\": 203, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"208\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 204, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.2366, \"times_seen\": null}, {\"site\": 204, \"mutant\": \"H\", \"escape\": 0.04952060521402526, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.2003, \"times_seen\": 63.0}, {\"site\": 204, \"mutant\": \"L\", \"escape\": -0.00276260190069237, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.045, \"times_seen\": 55.0}, {\"site\": 204, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 204, \"mutant\": \"Q\", \"escape\": 0.001702490090383066, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.0731, \"times_seen\": 6.0}, {\"site\": 204, \"mutant\": \"R\", \"escape\": -0.042118735186970714, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.0513, \"times_seen\": 14.0}, {\"site\": 204, \"mutant\": \"S\", \"escape\": -0.0008403092681013948, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": -0.0455, \"times_seen\": 33.0}, {\"site\": 204, \"mutant\": \"T\", \"escape\": 0.01471350834191945, \"epitope\": \"epitope 1\", \"reference_site\": \"209\", \"functional effect\": 0.1251, \"times_seen\": 29.0}, {\"site\": 205, \"mutant\": \"-\", \"escape\": -0.05785366780749396, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -0.0943, \"times_seen\": 21.0}, {\"site\": 205, \"mutant\": \"F\", \"escape\": -0.006824377407803956, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0024, \"times_seen\": 33.0}, {\"site\": 205, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 205, \"mutant\": \"L\", \"escape\": -0.016689840143541454, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0427, \"times_seen\": 4.0}, {\"site\": 205, \"mutant\": \"N\", \"escape\": -0.0016200604826874803, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.1542, \"times_seen\": 6.0}, {\"site\": 205, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -3.1276, \"times_seen\": null}, {\"site\": 205, \"mutant\": \"T\", \"escape\": 0.7071796270349411, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": 0.0091, \"times_seen\": 66.0}, {\"site\": 205, \"mutant\": \"V\", \"escape\": -0.0001546927632315407, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -0.0732, \"times_seen\": 28.0}, {\"site\": 205, \"mutant\": \"Y\", \"escape\": -0.033134010042315434, \"epitope\": \"epitope 1\", \"reference_site\": \"210\", \"functional effect\": -0.0985, \"times_seen\": 21.0}, {\"site\": 206, \"mutant\": \"*\", \"escape\": -0.0001998343069687565, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -2.7994, \"times_seen\": 4.0}, {\"site\": 206, \"mutant\": \"A\", \"escape\": -1.8698197645320904, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0728, \"times_seen\": 122.0}, {\"site\": 206, \"mutant\": \"C\", \"escape\": 0.11054989388380598, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0454, \"times_seen\": 97.0}, {\"site\": 206, \"mutant\": \"D\", \"escape\": -0.28929628877924124, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0567, \"times_seen\": 102.0}, {\"site\": 206, \"mutant\": \"E\", \"escape\": -0.06092077709949531, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.065, \"times_seen\": 42.0}, {\"site\": 206, \"mutant\": \"F\", \"escape\": -0.013547859122707197, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0738, \"times_seen\": 149.0}, {\"site\": 206, \"mutant\": \"G\", \"escape\": 0.08621158995388607, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0576, \"times_seen\": 81.0}, {\"site\": 206, \"mutant\": \"H\", \"escape\": -0.5346210580745578, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0446, \"times_seen\": 96.0}, {\"site\": 206, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 206, \"mutant\": \"K\", \"escape\": 0.013634392440242941, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0143, \"times_seen\": 34.0}, {\"site\": 206, \"mutant\": \"L\", \"escape\": -0.3484038725470576, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0161, \"times_seen\": 133.0}, {\"site\": 206, \"mutant\": \"M\", \"escape\": -0.057163711184284434, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0034, \"times_seen\": 32.0}, {\"site\": 206, \"mutant\": \"N\", \"escape\": 0.0973007063507476, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0533, \"times_seen\": 96.0}, {\"site\": 206, \"mutant\": \"P\", \"escape\": 0.582242436105122, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0835, \"times_seen\": 89.0}, {\"site\": 206, \"mutant\": \"Q\", \"escape\": -0.24573813435490358, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.1415, \"times_seen\": 24.0}, {\"site\": 206, \"mutant\": \"R\", \"escape\": -0.29816218298468034, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0084, \"times_seen\": 153.0}, {\"site\": 206, \"mutant\": \"S\", \"escape\": -0.10041042305099718, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": -0.0246, \"times_seen\": 308.0}, {\"site\": 206, \"mutant\": \"T\", \"escape\": 0.04122292035855464, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.052, \"times_seen\": 149.0}, {\"site\": 206, \"mutant\": \"V\", \"escape\": -0.06837633480519725, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0672, \"times_seen\": 149.0}, {\"site\": 206, \"mutant\": \"W\", \"escape\": -0.019255464347786203, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0393, \"times_seen\": 25.0}, {\"site\": 206, \"mutant\": \"Y\", \"escape\": 0.06190026673144961, \"epitope\": \"epitope 1\", \"reference_site\": \"212\", \"functional effect\": 0.0431, \"times_seen\": 81.0}, {\"site\": 207, \"mutant\": \"A\", \"escape\": -0.048843047757270344, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0563, \"times_seen\": 71.0}, {\"site\": 207, \"mutant\": \"E\", \"escape\": 0.08782061900627487, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0368, \"times_seen\": 30.0}, {\"site\": 207, \"mutant\": \"F\", \"escape\": -0.0371099403730232, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": -0.0004, \"times_seen\": 25.0}, {\"site\": 207, \"mutant\": \"G\", \"escape\": 0.02717871550457851, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0089, \"times_seen\": 17.0}, {\"site\": 207, \"mutant\": \"L\", \"escape\": -0.36686236498768116, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": -0.0977, \"times_seen\": 82.0}, {\"site\": 207, \"mutant\": \"M\", \"escape\": -0.19787083800816485, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0099, \"times_seen\": 99.0}, {\"site\": 207, \"mutant\": \"P\", \"escape\": 0.005670597540755286, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.1557, \"times_seen\": 5.0}, {\"site\": 207, \"mutant\": \"R\", \"escape\": 1.272415956782067, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0342, \"times_seen\": 27.0}, {\"site\": 207, \"mutant\": \"S\", \"escape\": 0.6094809408376796, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": -0.1629, \"times_seen\": 16.0}, {\"site\": 207, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"213\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"-\", \"escape\": -0.024967433776159245, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.1074, \"times_seen\": 19.0}, {\"site\": 208, \"mutant\": \"A\", \"escape\": 0.010399715910358136, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0533, \"times_seen\": 4.0}, {\"site\": 208, \"mutant\": \"C\", \"escape\": 0.051769481806629235, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.2796, \"times_seen\": 16.0}, {\"site\": 208, \"mutant\": \"E\", \"escape\": -0.010645148477214554, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0487, \"times_seen\": 5.0}, {\"site\": 208, \"mutant\": \"G\", \"escape\": -0.03203528940770418, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.2323, \"times_seen\": 16.0}, {\"site\": 208, \"mutant\": \"H\", \"escape\": 0.02543664843623727, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.1525, \"times_seen\": 10.0}, {\"site\": 208, \"mutant\": \"I\", \"escape\": 0.05643273340162964, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.1284, \"times_seen\": 13.0}, {\"site\": 208, \"mutant\": \"K\", \"escape\": 0.0003130966991041123, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0091, \"times_seen\": 5.0}, {\"site\": 208, \"mutant\": \"L\", \"escape\": -0.023676566906379183, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0282, \"times_seen\": 17.0}, {\"site\": 208, \"mutant\": \"M\", \"escape\": 0.02461194766435799, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.4161, \"times_seen\": 4.0}, {\"site\": 208, \"mutant\": \"P\", \"escape\": 0.01512579153195436, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.0108, \"times_seen\": 1.0}, {\"site\": 208, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"S\", \"escape\": -0.007971472999291846, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0509, \"times_seen\": 33.0}, {\"site\": 208, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -3.0402, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": -0.031, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"Y\", \"escape\": -0.02394897423002054, \"epitope\": \"epitope 1\", \"reference_site\": \"214\", \"functional effect\": 0.0297, \"times_seen\": 8.0}, {\"site\": 209, \"mutant\": \"*\", \"escape\": 0.016125574912696686, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -2.8369, \"times_seen\": 2.0}, {\"site\": 209, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -3.0075, \"times_seen\": null}, {\"site\": 209, \"mutant\": \"A\", \"escape\": -0.17039330026636018, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0425, \"times_seen\": 111.0}, {\"site\": 209, \"mutant\": \"C\", \"escape\": -0.20870742526595848, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.283, \"times_seen\": 29.0}, {\"site\": 209, \"mutant\": \"D\", \"escape\": -0.04122973698566828, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0912, \"times_seen\": 81.0}, {\"site\": 209, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 209, \"mutant\": \"F\", \"escape\": -0.034765484281115464, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.016, \"times_seen\": 28.0}, {\"site\": 209, \"mutant\": \"G\", \"escape\": -0.4060975668504859, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0477, \"times_seen\": 115.0}, {\"site\": 209, \"mutant\": \"H\", \"escape\": -0.08019402365472166, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0683, \"times_seen\": 38.0}, {\"site\": 209, \"mutant\": \"I\", \"escape\": -0.03062212815860457, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0731, \"times_seen\": 23.0}, {\"site\": 209, \"mutant\": \"K\", \"escape\": 0.25883871495458405, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0464, \"times_seen\": 72.0}, {\"site\": 209, \"mutant\": \"L\", \"escape\": -0.24494683966601768, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0069, \"times_seen\": 118.0}, {\"site\": 209, \"mutant\": \"M\", \"escape\": -0.10612898888368208, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0198, \"times_seen\": 34.0}, {\"site\": 209, \"mutant\": \"N\", \"escape\": -0.035207435971186765, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0274, \"times_seen\": 42.0}, {\"site\": 209, \"mutant\": \"P\", \"escape\": -0.17572310095066723, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.019, \"times_seen\": 78.0}, {\"site\": 209, \"mutant\": \"Q\", \"escape\": -0.0015645444774564441, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0158, \"times_seen\": 65.0}, {\"site\": 209, \"mutant\": \"R\", \"escape\": -0.0018148987104183282, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0711, \"times_seen\": 118.0}, {\"site\": 209, \"mutant\": \"S\", \"escape\": -1.9821892626881066, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.0461, \"times_seen\": 117.0}, {\"site\": 209, \"mutant\": \"T\", \"escape\": 0.13792498172197146, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0859, \"times_seen\": 81.0}, {\"site\": 209, \"mutant\": \"V\", \"escape\": -0.03057035005165274, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0544, \"times_seen\": 70.0}, {\"site\": 209, \"mutant\": \"W\", \"escape\": 0.03516848874005135, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": 0.043, \"times_seen\": 30.0}, {\"site\": 209, \"mutant\": \"Y\", \"escape\": -0.13745197382581437, \"epitope\": \"epitope 1\", \"reference_site\": \"214a\", \"functional effect\": -0.0822, \"times_seen\": 29.0}, {\"site\": 210, \"mutant\": \"*\", \"escape\": -0.03494925224941279, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -2.2306, \"times_seen\": 3.0}, {\"site\": 210, \"mutant\": \"A\", \"escape\": -0.013847002887719109, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0818, \"times_seen\": 89.0}, {\"site\": 210, \"mutant\": \"C\", \"escape\": -0.6115640169608378, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.1751, \"times_seen\": 43.0}, {\"site\": 210, \"mutant\": \"D\", \"escape\": -0.05157328241614933, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0387, \"times_seen\": 29.0}, {\"site\": 210, \"mutant\": \"E\", \"escape\": -0.1858452788659321, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0924, \"times_seen\": 13.0}, {\"site\": 210, \"mutant\": \"F\", \"escape\": 0.2854972320481851, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1341, \"times_seen\": 45.0}, {\"site\": 210, \"mutant\": \"G\", \"escape\": -0.02642111011818517, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0187, \"times_seen\": 50.0}, {\"site\": 210, \"mutant\": \"H\", \"escape\": -0.008732621064873144, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0759, \"times_seen\": 65.0}, {\"site\": 210, \"mutant\": \"I\", \"escape\": -0.0001544583316363297, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1244, \"times_seen\": 35.0}, {\"site\": 210, \"mutant\": \"K\", \"escape\": 0.023588031865394144, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1741, \"times_seen\": 21.0}, {\"site\": 210, \"mutant\": \"L\", \"escape\": -0.08168769708609928, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0442, \"times_seen\": 165.0}, {\"site\": 210, \"mutant\": \"M\", \"escape\": 0.09072836772492839, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0042, \"times_seen\": 25.0}, {\"site\": 210, \"mutant\": \"N\", \"escape\": 0.19064332396727415, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0743, \"times_seen\": 46.0}, {\"site\": 210, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 210, \"mutant\": \"Q\", \"escape\": 0.06801731975420881, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.048, \"times_seen\": 30.0}, {\"site\": 210, \"mutant\": \"R\", \"escape\": -0.20216412078953974, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0616, \"times_seen\": 139.0}, {\"site\": 210, \"mutant\": \"S\", \"escape\": -0.016015406595059418, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0353, \"times_seen\": 162.0}, {\"site\": 210, \"mutant\": \"T\", \"escape\": -0.07613036677440181, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0405, \"times_seen\": 108.0}, {\"site\": 210, \"mutant\": \"V\", \"escape\": -0.026902762736486275, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": -0.0603, \"times_seen\": 33.0}, {\"site\": 210, \"mutant\": \"W\", \"escape\": -0.03293788334410576, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.1366, \"times_seen\": 17.0}, {\"site\": 210, \"mutant\": \"Y\", \"escape\": -0.05940343884039871, \"epitope\": \"epitope 1\", \"reference_site\": \"214b\", \"functional effect\": 0.0338, \"times_seen\": 40.0}, {\"site\": 211, \"mutant\": \"*\", \"escape\": 0.7453312285632056, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -2.7538, \"times_seen\": 10.0}, {\"site\": 211, \"mutant\": \"-\", \"escape\": 0.015324213199765888, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0252, \"times_seen\": 1.0}, {\"site\": 211, \"mutant\": \"A\", \"escape\": -0.018768653892256883, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0406, \"times_seen\": 142.0}, {\"site\": 211, \"mutant\": \"C\", \"escape\": -0.015911240489546223, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0276, \"times_seen\": 36.0}, {\"site\": 211, \"mutant\": \"D\", \"escape\": -0.21241753915237244, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0312, \"times_seen\": 120.0}, {\"site\": 211, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 211, \"mutant\": \"F\", \"escape\": 0.001960592321591016, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0032, \"times_seen\": 77.0}, {\"site\": 211, \"mutant\": \"G\", \"escape\": 0.2233277260910674, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0664, \"times_seen\": 203.0}, {\"site\": 211, \"mutant\": \"H\", \"escape\": -1.3541728925377972, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0951, \"times_seen\": 43.0}, {\"site\": 211, \"mutant\": \"I\", \"escape\": 0.0024254744922573997, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.135, \"times_seen\": 52.0}, {\"site\": 211, \"mutant\": \"K\", \"escape\": 0.040316305403577946, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0204, \"times_seen\": 105.0}, {\"site\": 211, \"mutant\": \"L\", \"escape\": 0.11607406410627383, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0025, \"times_seen\": 174.0}, {\"site\": 211, \"mutant\": \"M\", \"escape\": -0.2186194265939836, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0072, \"times_seen\": 84.0}, {\"site\": 211, \"mutant\": \"N\", \"escape\": -0.22281866053210073, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0045, \"times_seen\": 43.0}, {\"site\": 211, \"mutant\": \"P\", \"escape\": -0.07399919412693369, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0316, \"times_seen\": 115.0}, {\"site\": 211, \"mutant\": \"Q\", \"escape\": -0.05805343875536157, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0557, \"times_seen\": 81.0}, {\"site\": 211, \"mutant\": \"R\", \"escape\": -0.039470661503671074, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0215, \"times_seen\": 184.0}, {\"site\": 211, \"mutant\": \"S\", \"escape\": -0.023810755596332108, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0276, \"times_seen\": 177.0}, {\"site\": 211, \"mutant\": \"T\", \"escape\": -0.017296699519084656, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0269, \"times_seen\": 102.0}, {\"site\": 211, \"mutant\": \"V\", \"escape\": 0.011110777986376537, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": -0.0171, \"times_seen\": 181.0}, {\"site\": 211, \"mutant\": \"W\", \"escape\": -0.03553858909135092, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.0405, \"times_seen\": 71.0}, {\"site\": 211, \"mutant\": \"Y\", \"escape\": 0.4727998069936482, \"epitope\": \"epitope 1\", \"reference_site\": \"214c\", \"functional effect\": 0.066, \"times_seen\": 63.0}, {\"site\": 212, \"mutant\": \"*\", \"escape\": 0.05106921423644735, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -2.5539, \"times_seen\": 3.0}, {\"site\": 212, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 212, \"mutant\": \"A\", \"escape\": -0.07713335378245376, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1064, \"times_seen\": 201.0}, {\"site\": 212, \"mutant\": \"C\", \"escape\": -0.06948583971458912, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.2074, \"times_seen\": 59.0}, {\"site\": 212, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 212, \"mutant\": \"E\", \"escape\": -0.17251452789671506, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0597, \"times_seen\": 127.0}, {\"site\": 212, \"mutant\": \"F\", \"escape\": -0.17716113649036577, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1832, \"times_seen\": 51.0}, {\"site\": 212, \"mutant\": \"G\", \"escape\": 0.13336657501552665, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1224, \"times_seen\": 143.0}, {\"site\": 212, \"mutant\": \"H\", \"escape\": 0.11073318044408867, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0769, \"times_seen\": 207.0}, {\"site\": 212, \"mutant\": \"I\", \"escape\": -0.04061914327739125, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": 0.0437, \"times_seen\": 74.0}, {\"site\": 212, \"mutant\": \"K\", \"escape\": -0.04111030152858731, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.026, \"times_seen\": 35.0}, {\"site\": 212, \"mutant\": \"L\", \"escape\": 0.07470288998764203, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1598, \"times_seen\": 101.0}, {\"site\": 212, \"mutant\": \"M\", \"escape\": -0.002635528266987849, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1444, \"times_seen\": 34.0}, {\"site\": 212, \"mutant\": \"N\", \"escape\": 0.033490392485897746, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0638, \"times_seen\": 226.0}, {\"site\": 212, \"mutant\": \"P\", \"escape\": -0.3084298245158928, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1075, \"times_seen\": 108.0}, {\"site\": 212, \"mutant\": \"Q\", \"escape\": -0.10577396443484854, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0803, \"times_seen\": 18.0}, {\"site\": 212, \"mutant\": \"R\", \"escape\": 0.0732875077195028, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.2016, \"times_seen\": 93.0}, {\"site\": 212, \"mutant\": \"S\", \"escape\": -2.368656339021131, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0871, \"times_seen\": 213.0}, {\"site\": 212, \"mutant\": \"T\", \"escape\": 0.016834553549146054, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.1353, \"times_seen\": 135.0}, {\"site\": 212, \"mutant\": \"V\", \"escape\": -0.12239558594689516, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0999, \"times_seen\": 141.0}, {\"site\": 212, \"mutant\": \"W\", \"escape\": -0.10934684135510853, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.2008, \"times_seen\": 12.0}, {\"site\": 212, \"mutant\": \"Y\", \"escape\": -0.07887693534633118, \"epitope\": \"epitope 1\", \"reference_site\": \"215\", \"functional effect\": -0.0367, \"times_seen\": 271.0}, {\"site\": 213, \"mutant\": \"-\", \"escape\": 0.006474845277467173, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -1.3884, \"times_seen\": 4.0}, {\"site\": 213, \"mutant\": \"F\", \"escape\": 0.1254247466072933, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.1345, \"times_seen\": 44.0}, {\"site\": 213, \"mutant\": \"I\", \"escape\": 0.027216050491319862, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.0486, \"times_seen\": 14.0}, {\"site\": 213, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 213, \"mutant\": \"M\", \"escape\": -0.046588051052807826, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": 0.0678, \"times_seen\": 11.0}, {\"site\": 213, \"mutant\": \"P\", \"escape\": -1.2679129657916017, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.8257, \"times_seen\": 85.0}, {\"site\": 213, \"mutant\": \"Q\", \"escape\": -0.009488988911470092, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.8349, \"times_seen\": 3.0}, {\"site\": 213, \"mutant\": \"R\", \"escape\": -0.004859660315142473, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.7414, \"times_seen\": 2.0}, {\"site\": 213, \"mutant\": \"S\", \"escape\": -0.010224141870133254, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -1.2806, \"times_seen\": 2.0}, {\"site\": 213, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"216\", \"functional effect\": -0.3526, \"times_seen\": null}, {\"site\": 214, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 214, \"mutant\": \"H\", \"escape\": -0.03673148336175288, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.1613, \"times_seen\": 14.0}, {\"site\": 214, \"mutant\": \"L\", \"escape\": -0.034868051293897376, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": -0.0103, \"times_seen\": 7.0}, {\"site\": 214, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 214, \"mutant\": \"Q\", \"escape\": 0.012112001680993427, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": 0.2183, \"times_seen\": 4.0}, {\"site\": 214, \"mutant\": \"S\", \"escape\": 0.017567206628656757, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": -0.003, \"times_seen\": 31.0}, {\"site\": 214, \"mutant\": \"T\", \"escape\": -0.0011826049865548635, \"epitope\": \"epitope 1\", \"reference_site\": \"217\", \"functional effect\": -0.062, \"times_seen\": 6.0}, {\"site\": 215, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -2.7657, \"times_seen\": null}, {\"site\": 215, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 215, \"mutant\": \"E\", \"escape\": -0.008863968171722574, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0077, \"times_seen\": 64.0}, {\"site\": 215, \"mutant\": \"H\", \"escape\": -0.13462203832881517, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0328, \"times_seen\": 124.0}, {\"site\": 215, \"mutant\": \"K\", \"escape\": 0.05788339225913941, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.0633, \"times_seen\": 24.0}, {\"site\": 215, \"mutant\": \"L\", \"escape\": 0.07249460098081377, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1397, \"times_seen\": 85.0}, {\"site\": 215, \"mutant\": \"P\", \"escape\": 0.013320657477189558, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1498, \"times_seen\": 11.0}, {\"site\": 215, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 215, \"mutant\": \"R\", \"escape\": -0.0073054638054800124, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1316, \"times_seen\": 92.0}, {\"site\": 215, \"mutant\": \"S\", \"escape\": 0.009479321231783196, \"epitope\": \"epitope 1\", \"reference_site\": \"218\", \"functional effect\": -0.1756, \"times_seen\": 7.0}, {\"site\": 216, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 216, \"mutant\": \"C\", \"escape\": -0.012178543756088768, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.2669, \"times_seen\": 123.0}, {\"site\": 216, \"mutant\": \"D\", \"escape\": 0.18718553195876356, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.1246, \"times_seen\": 136.0}, {\"site\": 216, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0321, \"times_seen\": null}, {\"site\": 216, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 216, \"mutant\": \"N\", \"escape\": 0.020222691586795842, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.3667, \"times_seen\": 1.0}, {\"site\": 216, \"mutant\": \"R\", \"escape\": 0.0026451373811593073, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": 0.0003, \"times_seen\": 1.0}, {\"site\": 216, \"mutant\": \"S\", \"escape\": 0.2267351163598512, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.0416, \"times_seen\": 88.0}, {\"site\": 216, \"mutant\": \"V\", \"escape\": -0.0770165953106731, \"epitope\": \"epitope 1\", \"reference_site\": \"219\", \"functional effect\": -0.0095, \"times_seen\": 40.0}, {\"site\": 217, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 217, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": -1.2951, \"times_seen\": null}, {\"site\": 217, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 217, \"mutant\": \"I\", \"escape\": 0.011857808380789236, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.0326, \"times_seen\": 16.0}, {\"site\": 217, \"mutant\": \"L\", \"escape\": 0.04061982268003744, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.003, \"times_seen\": 18.0}, {\"site\": 217, \"mutant\": \"S\", \"escape\": 0.048155333319163565, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": -1.1228, \"times_seen\": 2.0}, {\"site\": 217, \"mutant\": \"V\", \"escape\": -0.013809578039958546, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": 0.1777, \"times_seen\": 6.0}, {\"site\": 217, \"mutant\": \"Y\", \"escape\": -0.0025194434157700977, \"epitope\": \"epitope 1\", \"reference_site\": \"220\", \"functional effect\": -1.0107, \"times_seen\": 1.0}, {\"site\": 218, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 218, \"mutant\": \"A\", \"escape\": -0.056662419142244506, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.1215, \"times_seen\": 8.0}, {\"site\": 218, \"mutant\": \"C\", \"escape\": -0.006850150956310626, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.343, \"times_seen\": 1.0}, {\"site\": 218, \"mutant\": \"F\", \"escape\": -0.007980582081593217, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.326, \"times_seen\": 20.0}, {\"site\": 218, \"mutant\": \"L\", \"escape\": 0.02629086333664125, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 218, \"mutant\": \"P\", \"escape\": -0.03918651574629352, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -1.9303, \"times_seen\": 18.0}, {\"site\": 218, \"mutant\": \"R\", \"escape\": -0.03385851937154476, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0561, \"times_seen\": 6.0}, {\"site\": 218, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 218, \"mutant\": \"T\", \"escape\": -0.041629702594978266, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": 0.0753, \"times_seen\": 12.0}, {\"site\": 218, \"mutant\": \"W\", \"escape\": -0.0049866059138621915, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.2838, \"times_seen\": 5.0}, {\"site\": 218, \"mutant\": \"Y\", \"escape\": -0.005852583273842963, \"epitope\": \"epitope 1\", \"reference_site\": \"221\", \"functional effect\": -0.0299, \"times_seen\": 3.0}, {\"site\": 219, \"mutant\": \"*\", \"escape\": -0.01746462676878807, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -2.9784, \"times_seen\": 2.0}, {\"site\": 219, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 219, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 219, \"mutant\": \"C\", \"escape\": -0.1597623061670389, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.0102, \"times_seen\": 35.0}, {\"site\": 219, \"mutant\": \"D\", \"escape\": -0.045524669395990106, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.4087, \"times_seen\": 43.0}, {\"site\": 219, \"mutant\": \"E\", \"escape\": 0.1466235381315655, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.5791, \"times_seen\": 6.0}, {\"site\": 219, \"mutant\": \"F\", \"escape\": 0.013666502949246697, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.6507, \"times_seen\": 24.0}, {\"site\": 219, \"mutant\": \"G\", \"escape\": -0.17212033735835636, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.2606, \"times_seen\": 66.0}, {\"site\": 219, \"mutant\": \"H\", \"escape\": 0.001949615782809941, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -2.2013, \"times_seen\": 5.0}, {\"site\": 219, \"mutant\": \"I\", \"escape\": 0.02720459721763285, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.1774, \"times_seen\": 43.0}, {\"site\": 219, \"mutant\": \"K\", \"escape\": -0.033152316945515105, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -3.1135, \"times_seen\": 1.0}, {\"site\": 219, \"mutant\": \"L\", \"escape\": 0.17171335855759332, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.1977, \"times_seen\": 61.0}, {\"site\": 219, \"mutant\": \"M\", \"escape\": -0.010209070425110638, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.6407, \"times_seen\": 12.0}, {\"site\": 219, \"mutant\": \"N\", \"escape\": -0.02317708973255393, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.8643, \"times_seen\": 13.0}, {\"site\": 219, \"mutant\": \"P\", \"escape\": 0.025177147904351008, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.1476, \"times_seen\": 120.0}, {\"site\": 219, \"mutant\": \"Q\", \"escape\": 0.011675865756465193, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.4284, \"times_seen\": 10.0}, {\"site\": 219, \"mutant\": \"R\", \"escape\": -0.00896955960530509, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.8129, \"times_seen\": 13.0}, {\"site\": 219, \"mutant\": \"S\", \"escape\": -0.493857845679122, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.2461, \"times_seen\": 124.0}, {\"site\": 219, \"mutant\": \"T\", \"escape\": 0.31157596373870644, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": 0.0355, \"times_seen\": 139.0}, {\"site\": 219, \"mutant\": \"V\", \"escape\": 0.01647716637008091, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -0.1999, \"times_seen\": 102.0}, {\"site\": 219, \"mutant\": \"W\", \"escape\": 0.009081183899690499, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.9779, \"times_seen\": 4.0}, {\"site\": 219, \"mutant\": \"Y\", \"escape\": 0.04008172094207605, \"epitope\": \"epitope 1\", \"reference_site\": \"222\", \"functional effect\": -1.8799, \"times_seen\": 9.0}, {\"site\": 220, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -2.4924, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -2.5797, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"M\", \"escape\": -0.0009151063332994537, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -0.2449, \"times_seen\": 1.0}, {\"site\": 220, \"mutant\": \"S\", \"escape\": 0.017550463505374713, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -1.6638, \"times_seen\": 8.0}, {\"site\": 220, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -0.9401, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"223\", \"functional effect\": -3.2667, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -2.5387, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"A\", \"escape\": 0.018811438758751173, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.3753, \"times_seen\": 9.0}, {\"site\": 221, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"G\", \"escape\": -0.005058956354355346, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -1.0164, \"times_seen\": 8.0}, {\"site\": 221, \"mutant\": \"K\", \"escape\": 0.005254295049390458, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.878, \"times_seen\": 21.0}, {\"site\": 221, \"mutant\": \"N\", \"escape\": -0.02619307814483693, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -1.3309, \"times_seen\": 6.0}, {\"site\": 221, \"mutant\": \"Q\", \"escape\": -0.006225725714428111, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": 0.0509, \"times_seen\": 5.0}, {\"site\": 221, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.4872, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"V\", \"escape\": -0.0035723374105176026, \"epitope\": \"epitope 1\", \"reference_site\": \"224\", \"functional effect\": -0.1249, \"times_seen\": 1.0}, {\"site\": 222, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 222, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.138, \"times_seen\": null}, {\"site\": 222, \"mutant\": \"H\", \"escape\": 0.0017232522353125299, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.1521, \"times_seen\": 13.0}, {\"site\": 222, \"mutant\": \"L\", \"escape\": -0.048100417258666046, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -1.3977, \"times_seen\": 21.0}, {\"site\": 222, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 222, \"mutant\": \"Q\", \"escape\": -0.005433337041774762, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.501, \"times_seen\": 1.0}, {\"site\": 222, \"mutant\": \"S\", \"escape\": -0.003878719092645471, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.604, \"times_seen\": 1.0}, {\"site\": 222, \"mutant\": \"T\", \"escape\": -0.023196880918209626, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.1988, \"times_seen\": 7.0}, {\"site\": 222, \"mutant\": \"V\", \"escape\": -0.012063754755327581, \"epitope\": \"epitope 1\", \"reference_site\": \"225\", \"functional effect\": -2.4981, \"times_seen\": 4.0}, {\"site\": 223, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 223, \"mutant\": \"F\", \"escape\": 0.002079214377014298, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.2731, \"times_seen\": 46.0}, {\"site\": 223, \"mutant\": \"I\", \"escape\": 0.016947425648863503, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0083, \"times_seen\": 9.0}, {\"site\": 223, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 223, \"mutant\": \"M\", \"escape\": 0.0011598227168087315, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.0651, \"times_seen\": 1.0}, {\"site\": 223, \"mutant\": \"P\", \"escape\": -0.001895243371452594, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -2.1574, \"times_seen\": 1.0}, {\"site\": 223, \"mutant\": \"Q\", \"escape\": -0.00625677596661661, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": 0.0396, \"times_seen\": 2.0}, {\"site\": 223, \"mutant\": \"S\", \"escape\": -0.0005712979115547966, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.6241, \"times_seen\": 5.0}, {\"site\": 223, \"mutant\": \"V\", \"escape\": 0.15616306535445884, \"epitope\": \"epitope 1\", \"reference_site\": \"226\", \"functional effect\": -0.1381, \"times_seen\": 24.0}, {\"site\": 224, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 224, \"mutant\": \"A\", \"escape\": 0.04194147788247356, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.1855, \"times_seen\": 28.0}, {\"site\": 224, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.0935, \"times_seen\": null}, {\"site\": 224, \"mutant\": \"G\", \"escape\": -0.08243272537088969, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.638, \"times_seen\": 9.0}, {\"site\": 224, \"mutant\": \"I\", \"escape\": 0.019326846838171582, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.0408, \"times_seen\": 23.0}, {\"site\": 224, \"mutant\": \"L\", \"escape\": 0.01444012415164904, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.1253, \"times_seen\": 44.0}, {\"site\": 224, \"mutant\": \"M\", \"escape\": 0.02331598037700687, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.1129, \"times_seen\": 9.0}, {\"site\": 224, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -3.0983, \"times_seen\": null}, {\"site\": 224, \"mutant\": \"T\", \"escape\": -0.002633046380660917, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": -0.0495, \"times_seen\": 10.0}, {\"site\": 224, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"227\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 225, \"mutant\": \"A\", \"escape\": 0.03866043862787869, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.0925, \"times_seen\": 14.0}, {\"site\": 225, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 225, \"mutant\": \"E\", \"escape\": 0.11047253891336463, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.023, \"times_seen\": 23.0}, {\"site\": 225, \"mutant\": \"G\", \"escape\": -0.05001081214887178, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.3678, \"times_seen\": 57.0}, {\"site\": 225, \"mutant\": \"H\", \"escape\": 0.8238976787006734, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.2091, \"times_seen\": 58.0}, {\"site\": 225, \"mutant\": \"N\", \"escape\": -0.02126339450848001, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": 0.1782, \"times_seen\": 33.0}, {\"site\": 225, \"mutant\": \"R\", \"escape\": -0.009272313096979753, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.0463, \"times_seen\": 5.0}, {\"site\": 225, \"mutant\": \"S\", \"escape\": 0.02436181531664006, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.3219, \"times_seen\": 13.0}, {\"site\": 225, \"mutant\": \"V\", \"escape\": -0.004845816938698927, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.3542, \"times_seen\": 2.0}, {\"site\": 225, \"mutant\": \"Y\", \"escape\": -0.01539078430595736, \"epitope\": \"epitope 1\", \"reference_site\": \"228\", \"functional effect\": -0.0169, \"times_seen\": 56.0}, {\"site\": 226, \"mutant\": \"F\", \"escape\": 0.02477412365077256, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -0.4365, \"times_seen\": 19.0}, {\"site\": 226, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 226, \"mutant\": \"M\", \"escape\": 4.159930159179475e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -0.1964, \"times_seen\": 10.0}, {\"site\": 226, \"mutant\": \"P\", \"escape\": 0.008169343202771387, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -1.6609, \"times_seen\": 10.0}, {\"site\": 226, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": 0.0504, \"times_seen\": null}, {\"site\": 226, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -1.7349, \"times_seen\": null}, {\"site\": 226, \"mutant\": \"S\", \"escape\": 0.031135569571876208, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": -0.715, \"times_seen\": 5.0}, {\"site\": 226, \"mutant\": \"V\", \"escape\": 0.01836979139381967, \"epitope\": \"epitope 1\", \"reference_site\": \"229\", \"functional effect\": 0.1363, \"times_seen\": 1.0}, {\"site\": 227, \"mutant\": \"A\", \"escape\": -0.02831540444161939, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": 0.2964, \"times_seen\": 9.0}, {\"site\": 227, \"mutant\": \"G\", \"escape\": 0.0034033430910663924, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.0536, \"times_seen\": 2.0}, {\"site\": 227, \"mutant\": \"L\", \"escape\": 0.03046094288511495, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -1.4392, \"times_seen\": 31.0}, {\"site\": 227, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 227, \"mutant\": \"Q\", \"escape\": -0.008624187112043168, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.6773, \"times_seen\": 7.0}, {\"site\": 227, \"mutant\": \"S\", \"escape\": 0.005732761357836212, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": 0.3933, \"times_seen\": 14.0}, {\"site\": 227, \"mutant\": \"T\", \"escape\": -0.038462217987484566, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.1116, \"times_seen\": 19.0}, {\"site\": 227, \"mutant\": \"V\", \"escape\": 0.00874081489976507, \"epitope\": \"epitope 1\", \"reference_site\": \"230\", \"functional effect\": -0.2995, \"times_seen\": 4.0}, {\"site\": 228, \"mutant\": \"F\", \"escape\": -0.009375465315691188, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.6077, \"times_seen\": 2.0}, {\"site\": 228, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 228, \"mutant\": \"L\", \"escape\": 0.4731183956350366, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.7924, \"times_seen\": 7.0}, {\"site\": 228, \"mutant\": \"M\", \"escape\": -1.1676897260138446, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.3036, \"times_seen\": 17.0}, {\"site\": 228, \"mutant\": \"N\", \"escape\": 0.006093580506633599, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -1.1128, \"times_seen\": 5.0}, {\"site\": 228, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": -0.0682, \"times_seen\": null}, {\"site\": 228, \"mutant\": \"T\", \"escape\": -0.036437863672328256, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": 0.1064, \"times_seen\": 24.0}, {\"site\": 228, \"mutant\": \"V\", \"escape\": 0.04973023206529821, \"epitope\": \"epitope 1\", \"reference_site\": \"231\", \"functional effect\": 0.2946, \"times_seen\": 7.0}, {\"site\": 229, \"mutant\": \"A\", \"escape\": -0.00010030898804220216, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.0781, \"times_seen\": 19.0}, {\"site\": 229, \"mutant\": \"C\", \"escape\": -0.1423447559605321, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.0445, \"times_seen\": 60.0}, {\"site\": 229, \"mutant\": \"D\", \"escape\": -0.5876339979579724, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.2295, \"times_seen\": 42.0}, {\"site\": 229, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 229, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 229, \"mutant\": \"K\", \"escape\": -0.013104794645541918, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -1.2574, \"times_seen\": 6.0}, {\"site\": 229, \"mutant\": \"R\", \"escape\": -0.0269308300621871, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": -0.8465, \"times_seen\": 16.0}, {\"site\": 229, \"mutant\": \"S\", \"escape\": 0.025115960805507643, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.1679, \"times_seen\": 35.0}, {\"site\": 229, \"mutant\": \"V\", \"escape\": -0.08851318125506591, \"epitope\": \"epitope 1\", \"reference_site\": \"232\", \"functional effect\": 0.1446, \"times_seen\": 31.0}, {\"site\": 230, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 230, \"mutant\": \"L\", \"escape\": 0.0016942874931194782, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.1623, \"times_seen\": 2.0}, {\"site\": 230, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -0.229, \"times_seen\": null}, {\"site\": 230, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.0646, \"times_seen\": null}, {\"site\": 230, \"mutant\": \"S\", \"escape\": -0.0025821092199457686, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -0.4334, \"times_seen\": 7.0}, {\"site\": 230, \"mutant\": \"T\", \"escape\": -0.9213647913754546, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -0.4892, \"times_seen\": 12.0}, {\"site\": 230, \"mutant\": \"V\", \"escape\": 0.008717027104501068, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": 0.0266, \"times_seen\": 10.0}, {\"site\": 230, \"mutant\": \"Y\", \"escape\": -0.01629483612846266, \"epitope\": \"epitope 1\", \"reference_site\": \"233\", \"functional effect\": -1.2702, \"times_seen\": 6.0}, {\"site\": 231, \"mutant\": \"-\", \"escape\": -0.002747064721503372, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": -3.2703, \"times_seen\": 1.0}, {\"site\": 231, \"mutant\": \"D\", \"escape\": -0.008009553711120923, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.1887, \"times_seen\": 15.0}, {\"site\": 231, \"mutant\": \"H\", \"escape\": -0.041802084139699915, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.2882, \"times_seen\": 10.0}, {\"site\": 231, \"mutant\": \"K\", \"escape\": -0.6770220537533617, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.0597, \"times_seen\": 27.0}, {\"site\": 231, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 231, \"mutant\": \"P\", \"escape\": -0.016705435154896565, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.4295, \"times_seen\": 9.0}, {\"site\": 231, \"mutant\": \"S\", \"escape\": -0.02880194002397555, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": -0.0906, \"times_seen\": 2.0}, {\"site\": 231, \"mutant\": \"T\", \"escape\": -0.031169643841143357, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 231, \"mutant\": \"Y\", \"escape\": -0.06289182386056426, \"epitope\": \"epitope 1\", \"reference_site\": \"234\", \"functional effect\": 0.2545, \"times_seen\": 23.0}, {\"site\": 232, \"mutant\": \"-\", \"escape\": 0.000509418274691162, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 232, \"mutant\": \"A\", \"escape\": 0.014630439112372186, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.9604, \"times_seen\": 2.0}, {\"site\": 232, \"mutant\": \"F\", \"escape\": 0.034200732541664766, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.5704, \"times_seen\": 15.0}, {\"site\": 232, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 232, \"mutant\": \"L\", \"escape\": -0.006977893598750985, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.2026, \"times_seen\": 3.0}, {\"site\": 232, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -2.8017, \"times_seen\": null}, {\"site\": 232, \"mutant\": \"S\", \"escape\": -0.0156777414084474, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -1.1048, \"times_seen\": 7.0}, {\"site\": 232, \"mutant\": \"T\", \"escape\": 0.09087628639854994, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -1.0273, \"times_seen\": 10.0}, {\"site\": 232, \"mutant\": \"V\", \"escape\": 0.010291705699048413, \"epitope\": \"epitope 1\", \"reference_site\": \"235\", \"functional effect\": -0.665, \"times_seen\": 3.0}, {\"site\": 233, \"mutant\": \"-\", \"escape\": 0.000161508254794282, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 233, \"mutant\": \"A\", \"escape\": 0.015633397313871526, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.0943, \"times_seen\": 2.0}, {\"site\": 233, \"mutant\": \"I\", \"escape\": 0.03871090211809296, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": -0.123, \"times_seen\": 4.0}, {\"site\": 233, \"mutant\": \"L\", \"escape\": 0.0022979865478484304, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 233, \"mutant\": \"N\", \"escape\": 0.010707012485395042, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 233, \"mutant\": \"S\", \"escape\": -0.011379102430912648, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": -0.1354, \"times_seen\": 4.0}, {\"site\": 233, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 233, \"mutant\": \"V\", \"escape\": -0.024204609257145872, \"epitope\": \"epitope 1\", \"reference_site\": \"236\", \"functional effect\": 0.3651, \"times_seen\": 8.0}, {\"site\": 234, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 234, \"mutant\": \"C\", \"escape\": 0.015115098717579616, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.1122, \"times_seen\": 16.0}, {\"site\": 234, \"mutant\": \"G\", \"escape\": 0.005861593551571534, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.0881, \"times_seen\": 35.0}, {\"site\": 234, \"mutant\": \"K\", \"escape\": 0.04012933437090016, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.0887, \"times_seen\": 56.0}, {\"site\": 234, \"mutant\": \"M\", \"escape\": -0.09267488382167254, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.1069, \"times_seen\": 60.0}, {\"site\": 234, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 234, \"mutant\": \"S\", \"escape\": -0.05143257059413662, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": 0.0239, \"times_seen\": 59.0}, {\"site\": 234, \"mutant\": \"W\", \"escape\": -0.006137248417550104, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": 0.1662, \"times_seen\": 2.0}, {\"site\": 234, \"mutant\": \"Y\", \"escape\": -0.024040743630017077, \"epitope\": \"epitope 1\", \"reference_site\": \"237\", \"functional effect\": -0.2899, \"times_seen\": 17.0}, {\"site\": 235, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 235, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": 0.0113, \"times_seen\": null}, {\"site\": 235, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 235, \"mutant\": \"I\", \"escape\": 0.05914653304864503, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.1208, \"times_seen\": 15.0}, {\"site\": 235, \"mutant\": \"L\", \"escape\": 0.009997999664245276, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.2954, \"times_seen\": 13.0}, {\"site\": 235, \"mutant\": \"S\", \"escape\": -0.0017279167709728163, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -2.7351, \"times_seen\": 1.0}, {\"site\": 235, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"238\", \"functional effect\": -0.1558, \"times_seen\": null}, {\"site\": 236, \"mutant\": \"*\", \"escape\": 0.10793513041398457, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -3.0623, \"times_seen\": 1.0}, {\"site\": 236, \"mutant\": \"E\", \"escape\": -0.011564656886782135, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.0871, \"times_seen\": 6.0}, {\"site\": 236, \"mutant\": \"H\", \"escape\": 0.008978215979361376, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.1024, \"times_seen\": 20.0}, {\"site\": 236, \"mutant\": \"K\", \"escape\": -0.015379849391181094, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": 0.0548, \"times_seen\": 14.0}, {\"site\": 236, \"mutant\": \"L\", \"escape\": -0.025106846963119857, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.0449, \"times_seen\": 21.0}, {\"site\": 236, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -2.1075, \"times_seen\": null}, {\"site\": 236, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 236, \"mutant\": \"R\", \"escape\": -0.12473686556159631, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": -0.018, \"times_seen\": 77.0}, {\"site\": 236, \"mutant\": \"T\", \"escape\": -0.003901441120002498, \"epitope\": \"epitope 1\", \"reference_site\": \"239\", \"functional effect\": 0.1525, \"times_seen\": 2.0}, {\"site\": 237, \"mutant\": \"A\", \"escape\": -0.026405817042092807, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0885, \"times_seen\": 13.0}, {\"site\": 237, \"mutant\": \"I\", \"escape\": -0.06061092719252812, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0874, \"times_seen\": 49.0}, {\"site\": 237, \"mutant\": \"L\", \"escape\": 0.0073600693706592805, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.169, \"times_seen\": 2.0}, {\"site\": 237, \"mutant\": \"N\", \"escape\": -0.021513345664079506, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.4746, \"times_seen\": 8.0}, {\"site\": 237, \"mutant\": \"S\", \"escape\": -0.0010421146501503665, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0441, \"times_seen\": 5.0}, {\"site\": 237, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 237, \"mutant\": \"V\", \"escape\": -0.0031320632577711825, \"epitope\": \"epitope 1\", \"reference_site\": \"240\", \"functional effect\": -0.0511, \"times_seen\": 10.0}, {\"site\": 238, \"mutant\": \"-\", \"escape\": -0.022367463599745757, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.0169, \"times_seen\": 26.0}, {\"site\": 238, \"mutant\": \"F\", \"escape\": -0.005682891827954747, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.4513, \"times_seen\": 7.0}, {\"site\": 238, \"mutant\": \"I\", \"escape\": 0.009078767325604987, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.0413, \"times_seen\": 2.0}, {\"site\": 238, \"mutant\": \"K\", \"escape\": -0.014364542547594974, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.1915, \"times_seen\": 2.0}, {\"site\": 238, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 238, \"mutant\": \"M\", \"escape\": -0.0036195031740323988, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.4464, \"times_seen\": 8.0}, {\"site\": 238, \"mutant\": \"P\", \"escape\": -0.00420048369378054, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -1.983, \"times_seen\": 2.0}, {\"site\": 238, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.0438, \"times_seen\": null}, {\"site\": 238, \"mutant\": \"R\", \"escape\": -0.0035220295694376297, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 238, \"mutant\": \"V\", \"escape\": 0.02213527163594054, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": 0.077, \"times_seen\": 15.0}, {\"site\": 238, \"mutant\": \"Y\", \"escape\": -0.008522479132440561, \"epitope\": \"epitope 1\", \"reference_site\": \"241\", \"functional effect\": -0.453, \"times_seen\": 5.0}, {\"site\": 239, \"mutant\": \"-\", \"escape\": -0.01767140925958656, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.0762, \"times_seen\": 14.0}, {\"site\": 239, \"mutant\": \"F\", \"escape\": 0.005220170742976401, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.1729, \"times_seen\": 13.0}, {\"site\": 239, \"mutant\": \"H\", \"escape\": 0.012058524351200953, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.3791, \"times_seen\": 8.0}, {\"site\": 239, \"mutant\": \"I\", \"escape\": -0.0048201574742169, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.1038, \"times_seen\": 7.0}, {\"site\": 239, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 239, \"mutant\": \"M\", \"escape\": -0.009584390703680577, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.1964, \"times_seen\": 3.0}, {\"site\": 239, \"mutant\": \"P\", \"escape\": 0.013589398031766741, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.1182, \"times_seen\": 9.0}, {\"site\": 239, \"mutant\": \"Q\", \"escape\": 0.05569627322883189, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.1558, \"times_seen\": 6.0}, {\"site\": 239, \"mutant\": \"R\", \"escape\": 0.00739580012151633, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.0741, \"times_seen\": 5.0}, {\"site\": 239, \"mutant\": \"V\", \"escape\": -0.013360274967815574, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": -0.0102, \"times_seen\": 4.0}, {\"site\": 239, \"mutant\": \"Y\", \"escape\": 0.001180893149074483, \"epitope\": \"epitope 1\", \"reference_site\": \"242\", \"functional effect\": 0.0411, \"times_seen\": 3.0}, {\"site\": 240, \"mutant\": \"-\", \"escape\": -0.016043072421944842, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0648, \"times_seen\": 23.0}, {\"site\": 240, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 240, \"mutant\": \"D\", \"escape\": 0.016301690781157653, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.003, \"times_seen\": 27.0}, {\"site\": 240, \"mutant\": \"F\", \"escape\": -0.0326018975389334, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.5302, \"times_seen\": 13.0}, {\"site\": 240, \"mutant\": \"G\", \"escape\": 1.426097088307358, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 240, \"mutant\": \"L\", \"escape\": 4.4242984307273574e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.1752, \"times_seen\": 4.0}, {\"site\": 240, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0181, \"times_seen\": null}, {\"site\": 240, \"mutant\": \"P\", \"escape\": 0.0601499472249457, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.1026, \"times_seen\": 14.0}, {\"site\": 240, \"mutant\": \"S\", \"escape\": -0.04047082416238494, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": 0.0128, \"times_seen\": 56.0}, {\"site\": 240, \"mutant\": \"T\", \"escape\": -0.3328957068486239, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.0384, \"times_seen\": 93.0}, {\"site\": 240, \"mutant\": \"V\", \"escape\": -0.045986203388913814, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.0605, \"times_seen\": 48.0}, {\"site\": 240, \"mutant\": \"Y\", \"escape\": -0.008362466420938791, \"epitope\": \"epitope 1\", \"reference_site\": \"243\", \"functional effect\": -0.0469, \"times_seen\": 12.0}, {\"site\": 241, \"mutant\": \"-\", \"escape\": -0.01396645461847598, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.0433, \"times_seen\": 14.0}, {\"site\": 241, \"mutant\": \"D\", \"escape\": -0.007033988821863037, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1124, \"times_seen\": 2.0}, {\"site\": 241, \"mutant\": \"F\", \"escape\": -0.01548975960043293, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.1492, \"times_seen\": 9.0}, {\"site\": 241, \"mutant\": \"I\", \"escape\": -0.008492152024970204, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.0313, \"times_seen\": 6.0}, {\"site\": 241, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 241, \"mutant\": \"M\", \"escape\": -1.2254435987833014, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.0693, \"times_seen\": 8.0}, {\"site\": 241, \"mutant\": \"P\", \"escape\": -0.0012317090298683115, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1182, \"times_seen\": 23.0}, {\"site\": 241, \"mutant\": \"Q\", \"escape\": -0.01127774734396609, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.3063, \"times_seen\": 1.0}, {\"site\": 241, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1266, \"times_seen\": null}, {\"site\": 241, \"mutant\": \"S\", \"escape\": -0.021483922181882466, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": -0.2637, \"times_seen\": 10.0}, {\"site\": 241, \"mutant\": \"V\", \"escape\": -0.003827283581717108, \"epitope\": \"epitope 1\", \"reference_site\": \"244\", \"functional effect\": 0.1729, \"times_seen\": 9.0}, {\"site\": 242, \"mutant\": \"-\", \"escape\": 0.06233352443986922, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": 0.1197, \"times_seen\": 15.0}, {\"site\": 242, \"mutant\": \"D\", \"escape\": -0.00447575338396155, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.1089, \"times_seen\": 5.0}, {\"site\": 242, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 242, \"mutant\": \"L\", \"escape\": 0.017408842480942148, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.628, \"times_seen\": 12.0}, {\"site\": 242, \"mutant\": \"N\", \"escape\": 0.033789458714522394, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.0195, \"times_seen\": 11.0}, {\"site\": 242, \"mutant\": \"P\", \"escape\": 0.0029270294954274827, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.0842, \"times_seen\": 13.0}, {\"site\": 242, \"mutant\": \"Q\", \"escape\": -0.011311361098722009, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": 0.1609, \"times_seen\": 2.0}, {\"site\": 242, \"mutant\": \"R\", \"escape\": -0.017328803867322586, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.0004, \"times_seen\": 17.0}, {\"site\": 242, \"mutant\": \"S\", \"escape\": -0.025366500731589883, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.1595, \"times_seen\": 6.0}, {\"site\": 242, \"mutant\": \"Y\", \"escape\": -0.09324501759846655, \"epitope\": \"epitope 1\", \"reference_site\": \"245\", \"functional effect\": -0.022, \"times_seen\": 66.0}, {\"site\": 243, \"mutant\": \"-\", \"escape\": 0.02188052011386935, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0957, \"times_seen\": 8.0}, {\"site\": 243, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0263, \"times_seen\": null}, {\"site\": 243, \"mutant\": \"E\", \"escape\": -0.00886262314660483, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0858, \"times_seen\": 12.0}, {\"site\": 243, \"mutant\": \"G\", \"escape\": 0.13548054283494876, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.1092, \"times_seen\": 62.0}, {\"site\": 243, \"mutant\": \"I\", \"escape\": -0.0016736162737274963, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": -0.0162, \"times_seen\": 42.0}, {\"site\": 243, \"mutant\": \"K\", \"escape\": 0.03233611417595782, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": -0.0306, \"times_seen\": 46.0}, {\"site\": 243, \"mutant\": \"M\", \"escape\": -0.006095763069327926, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.169, \"times_seen\": 9.0}, {\"site\": 243, \"mutant\": \"N\", \"escape\": 0.005986739017632589, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.1541, \"times_seen\": 7.0}, {\"site\": 243, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 243, \"mutant\": \"S\", \"escape\": 0.6712049416897317, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0437, \"times_seen\": 57.0}, {\"site\": 243, \"mutant\": \"T\", \"escape\": -0.08572809096511604, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": -0.0659, \"times_seen\": 25.0}, {\"site\": 243, \"mutant\": \"W\", \"escape\": 0.010709274060634445, \"epitope\": \"epitope 1\", \"reference_site\": \"246\", \"functional effect\": 0.0583, \"times_seen\": 29.0}, {\"site\": 244, \"mutant\": \"-\", \"escape\": 0.0692181437273821, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0932, \"times_seen\": 11.0}, {\"site\": 244, \"mutant\": \"C\", \"escape\": 0.018568227364036315, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.0591, \"times_seen\": 7.0}, {\"site\": 244, \"mutant\": \"F\", \"escape\": 0.016855379165557943, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.2911, \"times_seen\": 2.0}, {\"site\": 244, \"mutant\": \"G\", \"escape\": 0.49885224195653993, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0707, \"times_seen\": 20.0}, {\"site\": 244, \"mutant\": \"I\", \"escape\": -0.0470413920765799, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0197, \"times_seen\": 36.0}, {\"site\": 244, \"mutant\": \"N\", \"escape\": -0.030947219478994117, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0213, \"times_seen\": 32.0}, {\"site\": 244, \"mutant\": \"P\", \"escape\": 0.01383513360659337, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0426, \"times_seen\": 11.0}, {\"site\": 244, \"mutant\": \"R\", \"escape\": -0.03271708848321992, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": -0.0617, \"times_seen\": 8.0}, {\"site\": 244, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 244, \"mutant\": \"T\", \"escape\": -0.00426899057884559, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 244, \"mutant\": \"Y\", \"escape\": 0.00047363302366675405, \"epitope\": \"epitope 1\", \"reference_site\": \"247\", \"functional effect\": 0.0067, \"times_seen\": 2.0}, {\"site\": 245, \"mutant\": \"*\", \"escape\": -0.005893295964140615, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -1.6307, \"times_seen\": 2.0}, {\"site\": 245, \"mutant\": \"-\", \"escape\": 0.06719566748699654, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.0923, \"times_seen\": 14.0}, {\"site\": 245, \"mutant\": \"C\", \"escape\": -0.045114491428467976, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.1126, \"times_seen\": 48.0}, {\"site\": 245, \"mutant\": \"F\", \"escape\": 0.0014158649841625476, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.12, \"times_seen\": 17.0}, {\"site\": 245, \"mutant\": \"H\", \"escape\": -0.06312948982147196, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.0527, \"times_seen\": 61.0}, {\"site\": 245, \"mutant\": \"L\", \"escape\": 0.009864737645258723, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.3252, \"times_seen\": 4.0}, {\"site\": 245, \"mutant\": \"N\", \"escape\": 0.006368341603954387, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 245, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.3224, \"times_seen\": null}, {\"site\": 245, \"mutant\": \"S\", \"escape\": 0.09278617054612306, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": -0.0493, \"times_seen\": 17.0}, {\"site\": 245, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"248\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 246, \"mutant\": \"-\", \"escape\": 0.013233511209885213, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0026, \"times_seen\": 12.0}, {\"site\": 246, \"mutant\": \"F\", \"escape\": -0.07114706107228128, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0119, \"times_seen\": 23.0}, {\"site\": 246, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 246, \"mutant\": \"M\", \"escape\": 0.06120956068911552, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": -0.0304, \"times_seen\": 15.0}, {\"site\": 246, \"mutant\": \"P\", \"escape\": 0.008649841801038921, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.054, \"times_seen\": 34.0}, {\"site\": 246, \"mutant\": \"Q\", \"escape\": -0.009546848038682568, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": -0.1483, \"times_seen\": 2.0}, {\"site\": 246, \"mutant\": \"R\", \"escape\": -0.3527489620680404, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0215, \"times_seen\": 3.0}, {\"site\": 246, \"mutant\": \"S\", \"escape\": -0.039418741300724404, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.0081, \"times_seen\": 15.0}, {\"site\": 246, \"mutant\": \"V\", \"escape\": -0.013171204702300198, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": -0.042, \"times_seen\": 5.0}, {\"site\": 246, \"mutant\": \"W\", \"escape\": 0.008761207373909553, \"epitope\": \"epitope 1\", \"reference_site\": \"249\", \"functional effect\": 0.1009, \"times_seen\": 4.0}, {\"site\": 247, \"mutant\": \"-\", \"escape\": 0.026462214602923924, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0723, \"times_seen\": 38.0}, {\"site\": 247, \"mutant\": \"A\", \"escape\": 0.5020290224162862, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.0908, \"times_seen\": 31.0}, {\"site\": 247, \"mutant\": \"F\", \"escape\": -0.018115113932015738, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.2072, \"times_seen\": 6.0}, {\"site\": 247, \"mutant\": \"I\", \"escape\": -0.07374027951884793, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.0007, \"times_seen\": 63.0}, {\"site\": 247, \"mutant\": \"K\", \"escape\": 0.006789727394502844, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.3528, \"times_seen\": 6.0}, {\"site\": 247, \"mutant\": \"L\", \"escape\": 0.020902166751683385, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0803, \"times_seen\": 5.0}, {\"site\": 247, \"mutant\": \"N\", \"escape\": 0.05532094912326338, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0791, \"times_seen\": 48.0}, {\"site\": 247, \"mutant\": \"P\", \"escape\": 0.0036950037326919914, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0563, \"times_seen\": 12.0}, {\"site\": 247, \"mutant\": \"Q\", \"escape\": -0.010114469092757122, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0533, \"times_seen\": 7.0}, {\"site\": 247, \"mutant\": \"R\", \"escape\": -0.0030446740880749794, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": -0.5234, \"times_seen\": 2.0}, {\"site\": 247, \"mutant\": \"S\", \"escape\": -0.015804710431857633, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.3226, \"times_seen\": 11.0}, {\"site\": 247, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"250\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 248, \"mutant\": \"-\", \"escape\": 0.00010863920629903801, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0369, \"times_seen\": 23.0}, {\"site\": 248, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 248, \"mutant\": \"H\", \"escape\": -0.16962758912846293, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0713, \"times_seen\": 45.0}, {\"site\": 248, \"mutant\": \"L\", \"escape\": -0.0205665056570558, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0358, \"times_seen\": 27.0}, {\"site\": 248, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 248, \"mutant\": \"R\", \"escape\": -0.011593215807468957, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.4598, \"times_seen\": 4.0}, {\"site\": 248, \"mutant\": \"S\", \"escape\": 0.027229035190170506, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0942, \"times_seen\": 18.0}, {\"site\": 248, \"mutant\": \"T\", \"escape\": 0.5978183746413747, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.0788, \"times_seen\": 39.0}, {\"site\": 248, \"mutant\": \"V\", \"escape\": -0.0032485328185483035, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": -0.1832, \"times_seen\": 2.0}, {\"site\": 248, \"mutant\": \"Y\", \"escape\": -0.016598214042434695, \"epitope\": \"epitope 1\", \"reference_site\": \"251\", \"functional effect\": 0.2736, \"times_seen\": 11.0}, {\"site\": 249, \"mutant\": \"*\", \"escape\": 0.020121332798285423, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -2.368, \"times_seen\": 1.0}, {\"site\": 249, \"mutant\": \"-\", \"escape\": -0.0036570863908834397, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0209, \"times_seen\": 25.0}, {\"site\": 249, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -0.3516, \"times_seen\": null}, {\"site\": 249, \"mutant\": \"D\", \"escape\": -0.05576700526438097, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -0.0529, \"times_seen\": 37.0}, {\"site\": 249, \"mutant\": \"E\", \"escape\": -0.013860895211979064, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.2515, \"times_seen\": 11.0}, {\"site\": 249, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 249, \"mutant\": \"I\", \"escape\": 0.8660437459847868, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": -0.3223, \"times_seen\": 10.0}, {\"site\": 249, \"mutant\": \"L\", \"escape\": -0.012053441785829625, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.1264, \"times_seen\": 5.0}, {\"site\": 249, \"mutant\": \"R\", \"escape\": 0.15019323217581526, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0234, \"times_seen\": 21.0}, {\"site\": 249, \"mutant\": \"S\", \"escape\": 0.031010530107541703, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0032, \"times_seen\": 18.0}, {\"site\": 249, \"mutant\": \"V\", \"escape\": -0.0025653268808943338, \"epitope\": \"epitope 1\", \"reference_site\": \"252\", \"functional effect\": 0.0587, \"times_seen\": 40.0}, {\"site\": 250, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -2.9867, \"times_seen\": null}, {\"site\": 250, \"mutant\": \"-\", \"escape\": -0.007363508677533693, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -1.3579, \"times_seen\": 1.0}, {\"site\": 250, \"mutant\": \"A\", \"escape\": -0.130466298984636, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0694, \"times_seen\": 139.0}, {\"site\": 250, \"mutant\": \"C\", \"escape\": 0.0944901195883738, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0911, \"times_seen\": 21.0}, {\"site\": 250, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 250, \"mutant\": \"E\", \"escape\": 0.010619364457082487, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0047, \"times_seen\": 30.0}, {\"site\": 250, \"mutant\": \"F\", \"escape\": 0.047835354303462266, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.19, \"times_seen\": 36.0}, {\"site\": 250, \"mutant\": \"G\", \"escape\": -0.019437318555347968, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0226, \"times_seen\": 68.0}, {\"site\": 250, \"mutant\": \"H\", \"escape\": -0.04934184342172159, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0066, \"times_seen\": 47.0}, {\"site\": 250, \"mutant\": \"I\", \"escape\": 0.0029650309962450556, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.1172, \"times_seen\": 25.0}, {\"site\": 250, \"mutant\": \"K\", \"escape\": -2.095729216267758, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0792, \"times_seen\": 18.0}, {\"site\": 250, \"mutant\": \"L\", \"escape\": -0.011702721240167687, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.2095, \"times_seen\": 34.0}, {\"site\": 250, \"mutant\": \"M\", \"escape\": -0.012665613186359786, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0103, \"times_seen\": 6.0}, {\"site\": 250, \"mutant\": \"N\", \"escape\": 0.31115103017216794, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.048, \"times_seen\": 86.0}, {\"site\": 250, \"mutant\": \"P\", \"escape\": -0.02513177795325908, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0621, \"times_seen\": 48.0}, {\"site\": 250, \"mutant\": \"Q\", \"escape\": -0.023132792094051603, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0404, \"times_seen\": 14.0}, {\"site\": 250, \"mutant\": \"R\", \"escape\": -0.21211656134447102, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.1955, \"times_seen\": 43.0}, {\"site\": 250, \"mutant\": \"S\", \"escape\": -0.02143520798582373, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0687, \"times_seen\": 85.0}, {\"site\": 250, \"mutant\": \"T\", \"escape\": -0.664622724223309, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.1012, \"times_seen\": 52.0}, {\"site\": 250, \"mutant\": \"V\", \"escape\": 0.18303287094214254, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.0993, \"times_seen\": 47.0}, {\"site\": 250, \"mutant\": \"W\", \"escape\": -0.5210338210792754, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": -0.2328, \"times_seen\": 15.0}, {\"site\": 250, \"mutant\": \"Y\", \"escape\": -0.10186320148838297, \"epitope\": \"epitope 1\", \"reference_site\": \"253\", \"functional effect\": 0.0098, \"times_seen\": 89.0}, {\"site\": 251, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -2.8802, \"times_seen\": null}, {\"site\": 251, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -1.236, \"times_seen\": null}, {\"site\": 251, \"mutant\": \"A\", \"escape\": 0.004443513588775835, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0229, \"times_seen\": 43.0}, {\"site\": 251, \"mutant\": \"C\", \"escape\": 1.4586624734865057, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.247, \"times_seen\": 19.0}, {\"site\": 251, \"mutant\": \"D\", \"escape\": 0.004506143551448202, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.2769, \"times_seen\": 12.0}, {\"site\": 251, \"mutant\": \"E\", \"escape\": -0.016826264136130527, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.1792, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"F\", \"escape\": -0.0305298057919285, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0267, \"times_seen\": 55.0}, {\"site\": 251, \"mutant\": \"G\", \"escape\": -0.04493151907602673, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1268, \"times_seen\": 17.0}, {\"site\": 251, \"mutant\": \"H\", \"escape\": -0.0016632134358921756, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0095, \"times_seen\": 14.0}, {\"site\": 251, \"mutant\": \"I\", \"escape\": -1.6085864352470922, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.1429, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"K\", \"escape\": -0.020972343433331993, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1052, \"times_seen\": 10.0}, {\"site\": 251, \"mutant\": \"L\", \"escape\": 0.010259373876850827, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0779, \"times_seen\": 47.0}, {\"site\": 251, \"mutant\": \"M\", \"escape\": -0.0024492809985906644, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1178, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"N\", \"escape\": -0.018348954854899735, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.2366, \"times_seen\": 13.0}, {\"site\": 251, \"mutant\": \"P\", \"escape\": -0.053909759780029785, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0124, \"times_seen\": 98.0}, {\"site\": 251, \"mutant\": \"Q\", \"escape\": 0.0033821884176979643, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.1581, \"times_seen\": 9.0}, {\"site\": 251, \"mutant\": \"R\", \"escape\": -0.2838857147703259, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0805, \"times_seen\": 23.0}, {\"site\": 251, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 251, \"mutant\": \"T\", \"escape\": -0.26039140670766775, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0369, \"times_seen\": 72.0}, {\"site\": 251, \"mutant\": \"V\", \"escape\": -0.031095016857949555, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0644, \"times_seen\": 34.0}, {\"site\": 251, \"mutant\": \"W\", \"escape\": 0.0005014156605852362, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": -0.0808, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"Y\", \"escape\": -0.010918461733840444, \"epitope\": \"epitope 1\", \"reference_site\": \"254\", \"functional effect\": 0.0042, \"times_seen\": 51.0}, {\"site\": 252, \"mutant\": \"*\", \"escape\": -0.001696211089924075, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -2.7623, \"times_seen\": 2.0}, {\"site\": 252, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 252, \"mutant\": \"A\", \"escape\": 0.0749526185413519, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.022, \"times_seen\": 34.0}, {\"site\": 252, \"mutant\": \"C\", \"escape\": 0.003160924445600765, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1201, \"times_seen\": 9.0}, {\"site\": 252, \"mutant\": \"D\", \"escape\": 0.03488463893568477, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.2949, \"times_seen\": 17.0}, {\"site\": 252, \"mutant\": \"E\", \"escape\": -0.0007335335097867152, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1349, \"times_seen\": 10.0}, {\"site\": 252, \"mutant\": \"F\", \"escape\": 0.09388393301248373, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.09, \"times_seen\": 63.0}, {\"site\": 252, \"mutant\": \"G\", \"escape\": -0.003197460892110553, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0354, \"times_seen\": 16.0}, {\"site\": 252, \"mutant\": \"H\", \"escape\": -0.012471709935502067, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.2111, \"times_seen\": 9.0}, {\"site\": 252, \"mutant\": \"I\", \"escape\": -0.021257962025375787, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0747, \"times_seen\": 19.0}, {\"site\": 252, \"mutant\": \"K\", \"escape\": -0.005325891186101664, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.1087, \"times_seen\": 11.0}, {\"site\": 252, \"mutant\": \"L\", \"escape\": -0.8879300999497831, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.0646, \"times_seen\": 45.0}, {\"site\": 252, \"mutant\": \"M\", \"escape\": -0.010284868126910986, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1899, \"times_seen\": 5.0}, {\"site\": 252, \"mutant\": \"N\", \"escape\": 0.011897326442433076, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.2301, \"times_seen\": 8.0}, {\"site\": 252, \"mutant\": \"P\", \"escape\": -0.20351308816561067, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0354, \"times_seen\": 94.0}, {\"site\": 252, \"mutant\": \"Q\", \"escape\": 7.034353270057426e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.3266, \"times_seen\": 4.0}, {\"site\": 252, \"mutant\": \"R\", \"escape\": -0.004584212608827794, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.222, \"times_seen\": 16.0}, {\"site\": 252, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 252, \"mutant\": \"T\", \"escape\": -0.9983522951701947, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0208, \"times_seen\": 45.0}, {\"site\": 252, \"mutant\": \"V\", \"escape\": 0.01202709835769501, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.0605, \"times_seen\": 16.0}, {\"site\": 252, \"mutant\": \"W\", \"escape\": 0.01572736430900588, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": -0.1098, \"times_seen\": 9.0}, {\"site\": 252, \"mutant\": \"Y\", \"escape\": 0.011234025230357967, \"epitope\": \"epitope 1\", \"reference_site\": \"255\", \"functional effect\": 0.0438, \"times_seen\": 43.0}, {\"site\": 253, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 253, \"mutant\": \"A\", \"escape\": -0.016912726061481316, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.2278, \"times_seen\": 9.0}, {\"site\": 253, \"mutant\": \"C\", \"escape\": -0.0015996250973728551, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.0983, \"times_seen\": 1.0}, {\"site\": 253, \"mutant\": \"F\", \"escape\": -0.00671269896050509, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.1115, \"times_seen\": 2.0}, {\"site\": 253, \"mutant\": \"L\", \"escape\": 0.036400470047344625, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.0324, \"times_seen\": 27.0}, {\"site\": 253, \"mutant\": \"P\", \"escape\": -0.07791178597164805, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.0483, \"times_seen\": 40.0}, {\"site\": 253, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 253, \"mutant\": \"T\", \"escape\": -0.012534717383793744, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": -0.3463, \"times_seen\": 12.0}, {\"site\": 253, \"mutant\": \"Y\", \"escape\": -0.011492584207617906, \"epitope\": \"epitope 1\", \"reference_site\": \"256\", \"functional effect\": 0.3442, \"times_seen\": 5.0}, {\"site\": 254, \"mutant\": \"*\", \"escape\": -0.010129273671567197, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -3.1202, \"times_seen\": 2.0}, {\"site\": 254, \"mutant\": \"A\", \"escape\": 0.009299505475485284, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0133, \"times_seen\": 21.0}, {\"site\": 254, \"mutant\": \"C\", \"escape\": 0.08066002133166333, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.1041, \"times_seen\": 14.0}, {\"site\": 254, \"mutant\": \"D\", \"escape\": -0.09896503286336625, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0256, \"times_seen\": 54.0}, {\"site\": 254, \"mutant\": \"E\", \"escape\": -0.004476490096464452, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0481, \"times_seen\": 12.0}, {\"site\": 254, \"mutant\": \"F\", \"escape\": -0.030319765320165226, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0854, \"times_seen\": 10.0}, {\"site\": 254, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 254, \"mutant\": \"H\", \"escape\": 0.04913341235215903, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.2371, \"times_seen\": 9.0}, {\"site\": 254, \"mutant\": \"I\", \"escape\": -0.014277378013069353, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.104, \"times_seen\": 6.0}, {\"site\": 254, \"mutant\": \"K\", \"escape\": -0.008808325240352582, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.1809, \"times_seen\": 10.0}, {\"site\": 254, \"mutant\": \"L\", \"escape\": 0.00990116356023403, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0541, \"times_seen\": 16.0}, {\"site\": 254, \"mutant\": \"M\", \"escape\": 0.010527359834409325, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.1249, \"times_seen\": 8.0}, {\"site\": 254, \"mutant\": \"N\", \"escape\": 0.012323805941302073, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.0088, \"times_seen\": 18.0}, {\"site\": 254, \"mutant\": \"P\", \"escape\": 0.235534125387303, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0566, \"times_seen\": 18.0}, {\"site\": 254, \"mutant\": \"Q\", \"escape\": -0.00653446359983418, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": 0.1361, \"times_seen\": 3.0}, {\"site\": 254, \"mutant\": \"R\", \"escape\": -0.040657939163682884, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0423, \"times_seen\": 21.0}, {\"site\": 254, \"mutant\": \"S\", \"escape\": 0.2688968799161504, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0097, \"times_seen\": 41.0}, {\"site\": 254, \"mutant\": \"T\", \"escape\": -0.7415087573315322, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.021, \"times_seen\": 13.0}, {\"site\": 254, \"mutant\": \"V\", \"escape\": 0.014573864672419695, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.0902, \"times_seen\": 27.0}, {\"site\": 254, \"mutant\": \"W\", \"escape\": -0.022906913319092486, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.2542, \"times_seen\": 10.0}, {\"site\": 254, \"mutant\": \"Y\", \"escape\": 0.0005878134059298282, \"epitope\": \"epitope 1\", \"reference_site\": \"257\", \"functional effect\": -0.3191, \"times_seen\": 5.0}, {\"site\": 255, \"mutant\": \"*\", \"escape\": 0.028482462084889654, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -1.9373, \"times_seen\": 5.0}, {\"site\": 255, \"mutant\": \"C\", \"escape\": 0.0038037360439580857, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": 0.0905, \"times_seen\": 42.0}, {\"site\": 255, \"mutant\": \"F\", \"escape\": -0.0004016812884510983, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.1519, \"times_seen\": 6.0}, {\"site\": 255, \"mutant\": \"G\", \"escape\": -0.028953560698328853, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": 0.2637, \"times_seen\": 10.0}, {\"site\": 255, \"mutant\": \"L\", \"escape\": -0.01289160295900459, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.1184, \"times_seen\": 15.0}, {\"site\": 255, \"mutant\": \"R\", \"escape\": 0.025309934348744078, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.1066, \"times_seen\": 52.0}, {\"site\": 255, \"mutant\": \"S\", \"escape\": 0.019775855099428637, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": -0.0135, \"times_seen\": 7.0}, {\"site\": 255, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"258\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 256, \"mutant\": \"A\", \"escape\": -0.015611789174043121, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": -0.0462, \"times_seen\": 21.0}, {\"site\": 256, \"mutant\": \"I\", \"escape\": -0.21550388280691873, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.0035, \"times_seen\": 53.0}, {\"site\": 256, \"mutant\": \"K\", \"escape\": -0.01831267315595366, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.1198, \"times_seen\": 19.0}, {\"site\": 256, \"mutant\": \"N\", \"escape\": -0.0035779015893623173, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.3663, \"times_seen\": 1.0}, {\"site\": 256, \"mutant\": \"P\", \"escape\": 0.010696369841500566, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.0819, \"times_seen\": 8.0}, {\"site\": 256, \"mutant\": \"R\", \"escape\": -0.007837604938656926, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.059, \"times_seen\": 11.0}, {\"site\": 256, \"mutant\": \"S\", \"escape\": -0.04327886632023742, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.377, \"times_seen\": 5.0}, {\"site\": 256, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 256, \"mutant\": \"V\", \"escape\": 0.006206396776536959, \"epitope\": \"epitope 1\", \"reference_site\": \"259\", \"functional effect\": -0.159, \"times_seen\": 3.0}, {\"site\": 257, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": -0.0857, \"times_seen\": null}, {\"site\": 257, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 257, \"mutant\": \"D\", \"escape\": -0.9794705773267642, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0856, \"times_seen\": 52.0}, {\"site\": 257, \"mutant\": \"E\", \"escape\": -0.002792984709906266, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0222, \"times_seen\": 2.0}, {\"site\": 257, \"mutant\": \"F\", \"escape\": -0.00839854059880292, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 257, \"mutant\": \"G\", \"escape\": -0.034834031947745016, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.181, \"times_seen\": 14.0}, {\"site\": 257, \"mutant\": \"I\", \"escape\": -0.01650306062609922, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": -0.042, \"times_seen\": 6.0}, {\"site\": 257, \"mutant\": \"P\", \"escape\": -0.009659977202302682, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.1285, \"times_seen\": 9.0}, {\"site\": 257, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0593, \"times_seen\": null}, {\"site\": 257, \"mutant\": \"S\", \"escape\": -0.029910346632754783, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": -0.131, \"times_seen\": 36.0}, {\"site\": 257, \"mutant\": \"T\", \"escape\": 0.26047333540613604, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0958, \"times_seen\": 46.0}, {\"site\": 257, \"mutant\": \"V\", \"escape\": -0.13086368433376566, \"epitope\": \"epitope 1\", \"reference_site\": \"260\", \"functional effect\": 0.0007, \"times_seen\": 71.0}, {\"site\": 258, \"mutant\": \"*\", \"escape\": -0.007877701926698767, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -2.9356, \"times_seen\": 2.0}, {\"site\": 258, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -1.6178, \"times_seen\": null}, {\"site\": 258, \"mutant\": \"A\", \"escape\": 0.5246401544194573, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0449, \"times_seen\": 78.0}, {\"site\": 258, \"mutant\": \"C\", \"escape\": -0.11639112906536019, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0783, \"times_seen\": 58.0}, {\"site\": 258, \"mutant\": \"D\", \"escape\": -0.5114998040011789, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0359, \"times_seen\": 73.0}, {\"site\": 258, \"mutant\": \"E\", \"escape\": -0.07889730658518913, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.1557, \"times_seen\": 30.0}, {\"site\": 258, \"mutant\": \"F\", \"escape\": -0.07268269857049461, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0559, \"times_seen\": 31.0}, {\"site\": 258, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 258, \"mutant\": \"H\", \"escape\": 0.16441105062856654, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0955, \"times_seen\": 20.0}, {\"site\": 258, \"mutant\": \"I\", \"escape\": -0.09925178317782114, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0601, \"times_seen\": 23.0}, {\"site\": 258, \"mutant\": \"K\", \"escape\": -0.8100786902217644, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.067, \"times_seen\": 5.0}, {\"site\": 258, \"mutant\": \"L\", \"escape\": 0.3484625519964519, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0457, \"times_seen\": 58.0}, {\"site\": 258, \"mutant\": \"M\", \"escape\": -0.019464222547723797, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0449, \"times_seen\": 9.0}, {\"site\": 258, \"mutant\": \"N\", \"escape\": -1.2800182942705256, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0278, \"times_seen\": 29.0}, {\"site\": 258, \"mutant\": \"P\", \"escape\": 0.17924739969825668, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.047, \"times_seen\": 37.0}, {\"site\": 258, \"mutant\": \"Q\", \"escape\": 0.0017040382498976045, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.3115, \"times_seen\": 12.0}, {\"site\": 258, \"mutant\": \"R\", \"escape\": -0.10634654237319811, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0097, \"times_seen\": 93.0}, {\"site\": 258, \"mutant\": \"S\", \"escape\": 0.09734030529248515, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0399, \"times_seen\": 92.0}, {\"site\": 258, \"mutant\": \"T\", \"escape\": -0.15254795050740533, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0641, \"times_seen\": 34.0}, {\"site\": 258, \"mutant\": \"V\", \"escape\": -0.09756500859568668, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": 0.0049, \"times_seen\": 61.0}, {\"site\": 258, \"mutant\": \"W\", \"escape\": -0.07609291213093008, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0953, \"times_seen\": 10.0}, {\"site\": 258, \"mutant\": \"Y\", \"escape\": -0.006802505403901271, \"epitope\": \"epitope 1\", \"reference_site\": \"261\", \"functional effect\": -0.0368, \"times_seen\": 28.0}, {\"site\": 259, \"mutant\": \"*\", \"escape\": -0.01181501006218314, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -2.1507, \"times_seen\": 3.0}, {\"site\": 259, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 1.1621, \"times_seen\": null}, {\"site\": 259, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 259, \"mutant\": \"C\", \"escape\": 0.08118517345538045, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.1069, \"times_seen\": 32.0}, {\"site\": 259, \"mutant\": \"D\", \"escape\": 0.8406690583071629, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0076, \"times_seen\": 35.0}, {\"site\": 259, \"mutant\": \"E\", \"escape\": 0.027884666132824226, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0609, \"times_seen\": 17.0}, {\"site\": 259, \"mutant\": \"F\", \"escape\": 0.03186142244728464, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0082, \"times_seen\": 17.0}, {\"site\": 259, \"mutant\": \"G\", \"escape\": -0.012703802150426173, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0203, \"times_seen\": 31.0}, {\"site\": 259, \"mutant\": \"H\", \"escape\": -0.010948043143085359, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -0.0365, \"times_seen\": 17.0}, {\"site\": 259, \"mutant\": \"I\", \"escape\": -0.03569854309385992, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0746, \"times_seen\": 13.0}, {\"site\": 259, \"mutant\": \"K\", \"escape\": -0.013404350813372242, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.1179, \"times_seen\": 14.0}, {\"site\": 259, \"mutant\": \"L\", \"escape\": -0.034290135937899806, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0299, \"times_seen\": 46.0}, {\"site\": 259, \"mutant\": \"M\", \"escape\": -0.0059427814428247615, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0169, \"times_seen\": 10.0}, {\"site\": 259, \"mutant\": \"N\", \"escape\": -0.006319197344425438, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0233, \"times_seen\": 10.0}, {\"site\": 259, \"mutant\": \"P\", \"escape\": -0.09361878921038694, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -0.0905, \"times_seen\": 56.0}, {\"site\": 259, \"mutant\": \"Q\", \"escape\": 0.021321126424777445, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.066, \"times_seen\": 7.0}, {\"site\": 259, \"mutant\": \"R\", \"escape\": 0.11938729046748409, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.102, \"times_seen\": 43.0}, {\"site\": 259, \"mutant\": \"S\", \"escape\": -1.0140814910979778, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0822, \"times_seen\": 96.0}, {\"site\": 259, \"mutant\": \"T\", \"escape\": -0.04747029880120028, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.012, \"times_seen\": 76.0}, {\"site\": 259, \"mutant\": \"V\", \"escape\": -0.20520427116146744, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": -0.0147, \"times_seen\": 84.0}, {\"site\": 259, \"mutant\": \"W\", \"escape\": -0.037902479759343424, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.0732, \"times_seen\": 15.0}, {\"site\": 259, \"mutant\": \"Y\", \"escape\": 0.7283188278203564, \"epitope\": \"epitope 1\", \"reference_site\": \"262\", \"functional effect\": 0.2595, \"times_seen\": 16.0}, {\"site\": 260, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 260, \"mutant\": \"C\", \"escape\": -0.014677920485363092, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.0939, \"times_seen\": 7.0}, {\"site\": 260, \"mutant\": \"E\", \"escape\": -0.07181928090142699, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.0353, \"times_seen\": 12.0}, {\"site\": 260, \"mutant\": \"G\", \"escape\": 0.014886014211014754, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.055, \"times_seen\": 5.0}, {\"site\": 260, \"mutant\": \"I\", \"escape\": -0.0015561817880888102, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.1135, \"times_seen\": 5.0}, {\"site\": 260, \"mutant\": \"L\", \"escape\": -0.0022842933428981055, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": 0.2737, \"times_seen\": 3.0}, {\"site\": 260, \"mutant\": \"P\", \"escape\": -0.026650170245254144, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.0926, \"times_seen\": 8.0}, {\"site\": 260, \"mutant\": \"R\", \"escape\": 0.029622234829865614, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.3805, \"times_seen\": 3.0}, {\"site\": 260, \"mutant\": \"S\", \"escape\": 0.04823148124245081, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": 0.0867, \"times_seen\": 15.0}, {\"site\": 260, \"mutant\": \"T\", \"escape\": 0.23014283608841013, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.1126, \"times_seen\": 72.0}, {\"site\": 260, \"mutant\": \"V\", \"escape\": -0.060556914359981596, \"epitope\": \"epitope 1\", \"reference_site\": \"263\", \"functional effect\": -0.1314, \"times_seen\": 57.0}, {\"site\": 261, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 261, \"mutant\": \"D\", \"escape\": -0.003659140986034198, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.0692, \"times_seen\": 25.0}, {\"site\": 261, \"mutant\": \"G\", \"escape\": 0.021114554659403845, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.1399, \"times_seen\": 1.0}, {\"site\": 261, \"mutant\": \"L\", \"escape\": 0.3309295768924871, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.3907, \"times_seen\": 4.0}, {\"site\": 261, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": 0.0343, \"times_seen\": null}, {\"site\": 261, \"mutant\": \"S\", \"escape\": 0.22660445989983685, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": 0.007, \"times_seen\": 45.0}, {\"site\": 261, \"mutant\": \"T\", \"escape\": -0.36557855563676717, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.1058, \"times_seen\": 39.0}, {\"site\": 261, \"mutant\": \"V\", \"escape\": 0.7818717566742506, \"epitope\": \"epitope 1\", \"reference_site\": \"264\", \"functional effect\": -0.1244, \"times_seen\": 29.0}, {\"site\": 262, \"mutant\": \"*\", \"escape\": -0.003167566373341975, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": -3.1472, \"times_seen\": 1.0}, {\"site\": 262, \"mutant\": \"C\", \"escape\": -0.15794057094376043, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.0624, \"times_seen\": 41.0}, {\"site\": 262, \"mutant\": \"F\", \"escape\": -0.017133153083778187, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.0345, \"times_seen\": 26.0}, {\"site\": 262, \"mutant\": \"H\", \"escape\": 0.0418149032549485, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": -0.1187, \"times_seen\": 15.0}, {\"site\": 262, \"mutant\": \"L\", \"escape\": 0.052487184230711977, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": -0.2799, \"times_seen\": 5.0}, {\"site\": 262, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 262, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"265\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 263, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -3.1313, \"times_seen\": null}, {\"site\": 263, \"mutant\": \"C\", \"escape\": -0.010687991521169237, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.6806, \"times_seen\": 13.0}, {\"site\": 263, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -2.7898, \"times_seen\": null}, {\"site\": 263, \"mutant\": \"F\", \"escape\": 0.0016639373026619433, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.254, \"times_seen\": 3.0}, {\"site\": 263, \"mutant\": \"H\", \"escape\": 0.016548394603067045, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.2097, \"times_seen\": 24.0}, {\"site\": 263, \"mutant\": \"L\", \"escape\": 0.038455020337525965, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.1006, \"times_seen\": 8.0}, {\"site\": 263, \"mutant\": \"N\", \"escape\": -0.0030294458951043743, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.1918, \"times_seen\": 1.0}, {\"site\": 263, \"mutant\": \"Q\", \"escape\": 0.030525797421693885, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": -0.548, \"times_seen\": 3.0}, {\"site\": 263, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"266\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 264, \"mutant\": \"A\", \"escape\": -0.0031127282308492953, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.0664, \"times_seen\": 1.0}, {\"site\": 264, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.5584, \"times_seen\": null}, {\"site\": 264, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -2.6471, \"times_seen\": null}, {\"site\": 264, \"mutant\": \"L\", \"escape\": -0.007522737177376148, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.3599, \"times_seen\": 38.0}, {\"site\": 264, \"mutant\": \"M\", \"escape\": -0.05165332348323735, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": -0.3533, \"times_seen\": 31.0}, {\"site\": 264, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"267\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 265, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 265, \"mutant\": \"C\", \"escape\": -0.0059573037930554535, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.9919, \"times_seen\": 3.0}, {\"site\": 265, \"mutant\": \"D\", \"escape\": -0.014745169176921997, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.289, \"times_seen\": 4.0}, {\"site\": 265, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 265, \"mutant\": \"N\", \"escape\": -0.007748622561066649, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.2112, \"times_seen\": 1.0}, {\"site\": 265, \"mutant\": \"S\", \"escape\": -0.24770675089766675, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 265, \"mutant\": \"V\", \"escape\": -0.005906341274160435, \"epitope\": \"epitope 1\", \"reference_site\": \"268\", \"functional effect\": -2.8801, \"times_seen\": 1.0}, {\"site\": 266, \"mutant\": \"*\", \"escape\": 0.004269556097815547, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -3.0861, \"times_seen\": 1.0}, {\"site\": 266, \"mutant\": \"C\", \"escape\": 1.3167727502893405, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.3971, \"times_seen\": 15.0}, {\"site\": 266, \"mutant\": \"F\", \"escape\": -0.028305051086355396, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.0674, \"times_seen\": 13.0}, {\"site\": 266, \"mutant\": \"H\", \"escape\": -0.06365900234526703, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.0208, \"times_seen\": 42.0}, {\"site\": 266, \"mutant\": \"I\", \"escape\": 0.0022416940950000723, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.4324, \"times_seen\": 8.0}, {\"site\": 266, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": 0.0884, \"times_seen\": null}, {\"site\": 266, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": 0.7108, \"times_seen\": null}, {\"site\": 266, \"mutant\": \"Q\", \"escape\": 0.022560765064815618, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -0.226, \"times_seen\": 2.0}, {\"site\": 266, \"mutant\": \"S\", \"escape\": 0.06914740481438555, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": -1.7952, \"times_seen\": 1.0}, {\"site\": 266, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"269\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"F\", \"escape\": -0.0014834625981030947, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.5755, \"times_seen\": 3.0}, {\"site\": 267, \"mutant\": \"H\", \"escape\": -0.0030312445665895324, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 267, \"mutant\": \"I\", \"escape\": -0.06300225925139, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": 0.0225, \"times_seen\": 29.0}, {\"site\": 267, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"M\", \"escape\": -0.009309804881642328, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -0.3297, \"times_seen\": 6.0}, {\"site\": 267, \"mutant\": \"P\", \"escape\": -0.005975040186004463, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.1117, \"times_seen\": 4.0}, {\"site\": 267, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.2507, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -2.5835, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"V\", \"escape\": -0.006323892794612969, \"epitope\": \"epitope 1\", \"reference_site\": \"270\", \"functional effect\": -0.1038, \"times_seen\": 1.0}, {\"site\": 268, \"mutant\": \"*\", \"escape\": -0.006854220867975385, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -2.8702, \"times_seen\": 2.0}, {\"site\": 268, \"mutant\": \"E\", \"escape\": 0.052067548186103554, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.2675, \"times_seen\": 8.0}, {\"site\": 268, \"mutant\": \"H\", \"escape\": -0.0034010998611656977, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": 0.1361, \"times_seen\": 1.0}, {\"site\": 268, \"mutant\": \"K\", \"escape\": 0.024115867713222126, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": 0.0575, \"times_seen\": 48.0}, {\"site\": 268, \"mutant\": \"L\", \"escape\": -0.038994724082157824, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.1649, \"times_seen\": 19.0}, {\"site\": 268, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -1.7877, \"times_seen\": null}, {\"site\": 268, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 268, \"mutant\": \"R\", \"escape\": -0.02047114866574513, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.037, \"times_seen\": 6.0}, {\"site\": 268, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.1829, \"times_seen\": null}, {\"site\": 268, \"mutant\": \"V\", \"escape\": 0.006967560118285876, \"epitope\": \"epitope 1\", \"reference_site\": \"271\", \"functional effect\": -0.0978, \"times_seen\": 8.0}, {\"site\": 269, \"mutant\": \"F\", \"escape\": -0.005464889947740166, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.3883, \"times_seen\": 10.0}, {\"site\": 269, \"mutant\": \"H\", \"escape\": -0.04362973319390801, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.1072, \"times_seen\": 27.0}, {\"site\": 269, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.2025, \"times_seen\": null}, {\"site\": 269, \"mutant\": \"L\", \"escape\": -0.08444095420436785, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.2079, \"times_seen\": 37.0}, {\"site\": 269, \"mutant\": \"M\", \"escape\": 0.02054686056874027, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -0.0532, \"times_seen\": 7.0}, {\"site\": 269, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 269, \"mutant\": \"Q\", \"escape\": 0.02275565531897245, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -0.0278, \"times_seen\": 5.0}, {\"site\": 269, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -3.2083, \"times_seen\": null}, {\"site\": 269, \"mutant\": \"S\", \"escape\": 0.014295183780453314, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": -0.0187, \"times_seen\": 20.0}, {\"site\": 269, \"mutant\": \"T\", \"escape\": -0.05106431740590568, \"epitope\": \"epitope 1\", \"reference_site\": \"272\", \"functional effect\": 0.0631, \"times_seen\": 40.0}, {\"site\": 270, \"mutant\": \"E\", \"escape\": -0.010486395987198062, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -2.5379, \"times_seen\": 4.0}, {\"site\": 270, \"mutant\": \"G\", \"escape\": 0.0019525243304236706, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.5758, \"times_seen\": 18.0}, {\"site\": 270, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -1.3479, \"times_seen\": null}, {\"site\": 270, \"mutant\": \"K\", \"escape\": 0.2838359438081131, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.2049, \"times_seen\": 34.0}, {\"site\": 270, \"mutant\": \"M\", \"escape\": 0.03951267530493776, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -1.3312, \"times_seen\": 30.0}, {\"site\": 270, \"mutant\": \"Q\", \"escape\": 1.1532031345687639, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -1.0518, \"times_seen\": 6.0}, {\"site\": 270, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 270, \"mutant\": \"S\", \"escape\": -0.050700584996462086, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.272, \"times_seen\": 37.0}, {\"site\": 270, \"mutant\": \"T\", \"escape\": 0.005647584629429249, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.7768, \"times_seen\": 18.0}, {\"site\": 270, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"273\", \"functional effect\": -0.7758, \"times_seen\": null}, {\"site\": 271, \"mutant\": \"A\", \"escape\": -0.003755131051766131, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": 0.0215, \"times_seen\": 5.0}, {\"site\": 271, \"mutant\": \"D\", \"escape\": -0.003995227605949579, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.5077, \"times_seen\": 1.0}, {\"site\": 271, \"mutant\": \"I\", \"escape\": -0.07855442534282887, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.1285, \"times_seen\": 48.0}, {\"site\": 271, \"mutant\": \"L\", \"escape\": 0.002710534828560579, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.8816, \"times_seen\": 2.0}, {\"site\": 271, \"mutant\": \"N\", \"escape\": 0.08048643626916298, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.1565, \"times_seen\": 10.0}, {\"site\": 271, \"mutant\": \"P\", \"escape\": 0.009273132574760666, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.5376, \"times_seen\": 5.0}, {\"site\": 271, \"mutant\": \"S\", \"escape\": 0.01288380488028786, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": -0.0026, \"times_seen\": 2.0}, {\"site\": 271, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"274\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"C\", \"escape\": -0.03710380525645792, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -2.604, \"times_seen\": 3.0}, {\"site\": 272, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"I\", \"escape\": 0.014533275747803307, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -0.4407, \"times_seen\": 17.0}, {\"site\": 272, \"mutant\": \"L\", \"escape\": -0.0960798037887842, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": 0.1596, \"times_seen\": 22.0}, {\"site\": 272, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -2.9369, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -0.5865, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"275\", \"functional effect\": -0.1679, \"times_seen\": null}, {\"site\": 273, \"mutant\": \"I\", \"escape\": 0.011209821442466933, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.8345, \"times_seen\": 5.0}, {\"site\": 273, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 273, \"mutant\": \"M\", \"escape\": 1.6450179078862468, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.0186, \"times_seen\": 8.0}, {\"site\": 273, \"mutant\": \"P\", \"escape\": 0.03515087995077883, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -3.0628, \"times_seen\": 1.0}, {\"site\": 273, \"mutant\": \"Q\", \"escape\": 0.023977580137512756, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.9047, \"times_seen\": 8.0}, {\"site\": 273, \"mutant\": \"S\", \"escape\": 0.003956223250175923, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -2.8821, \"times_seen\": 2.0}, {\"site\": 273, \"mutant\": \"V\", \"escape\": -0.007764240894442178, \"epitope\": \"epitope 1\", \"reference_site\": \"276\", \"functional effect\": -0.9254, \"times_seen\": 7.0}, {\"site\": 274, \"mutant\": \"F\", \"escape\": 0.0043187556260205874, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.1495, \"times_seen\": 13.0}, {\"site\": 274, \"mutant\": \"I\", \"escape\": 0.040430196395133094, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.2832, \"times_seen\": 10.0}, {\"site\": 274, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 274, \"mutant\": \"M\", \"escape\": -0.001123977084934772, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.0198, \"times_seen\": 10.0}, {\"site\": 274, \"mutant\": \"P\", \"escape\": -0.2261849415867457, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": -2.5621, \"times_seen\": 3.0}, {\"site\": 274, \"mutant\": \"Q\", \"escape\": -0.004275595369512262, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 274, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 274, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"277\", \"functional effect\": -0.9872, \"times_seen\": null}, {\"site\": 275, \"mutant\": \"E\", \"escape\": -0.016292526031736317, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.2369, \"times_seen\": 6.0}, {\"site\": 275, \"mutant\": \"I\", \"escape\": 0.01290758404874112, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -1.1404, \"times_seen\": 2.0}, {\"site\": 275, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 275, \"mutant\": \"L\", \"escape\": 0.018559093083486577, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.0428, \"times_seen\": 8.0}, {\"site\": 275, \"mutant\": \"N\", \"escape\": 0.031078179915034518, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.1839, \"times_seen\": 13.0}, {\"site\": 275, \"mutant\": \"R\", \"escape\": -0.00013432687016756375, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -0.1017, \"times_seen\": 7.0}, {\"site\": 275, \"mutant\": \"V\", \"escape\": -0.012164420671087537, \"epitope\": \"epitope 1\", \"reference_site\": \"278\", \"functional effect\": -2.2104, \"times_seen\": 1.0}, {\"site\": 276, \"mutant\": \"*\", \"escape\": -0.0056851767184734016, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -2.0079, \"times_seen\": 2.0}, {\"site\": 276, \"mutant\": \"C\", \"escape\": -0.00662651826918805, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -1.7772, \"times_seen\": 2.0}, {\"site\": 276, \"mutant\": \"F\", \"escape\": -0.018427888652689624, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": 0.0871, \"times_seen\": 41.0}, {\"site\": 276, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -1.0005, \"times_seen\": null}, {\"site\": 276, \"mutant\": \"I\", \"escape\": -0.017912120073686543, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -0.6036, \"times_seen\": 9.0}, {\"site\": 276, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": -2.5458, \"times_seen\": null}, {\"site\": 276, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"279\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 277, \"mutant\": \"D\", \"escape\": 0.05278739106673781, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.0587, \"times_seen\": 13.0}, {\"site\": 277, \"mutant\": \"F\", \"escape\": 0.00619636893034182, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -2.2279, \"times_seen\": 4.0}, {\"site\": 277, \"mutant\": \"H\", \"escape\": 0.021571238372629586, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.5216, \"times_seen\": 1.0}, {\"site\": 277, \"mutant\": \"I\", \"escape\": -0.0038369083688290233, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 277, \"mutant\": \"K\", \"escape\": -0.0027432526525282214, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -2.205, \"times_seen\": 1.0}, {\"site\": 277, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 277, \"mutant\": \"S\", \"escape\": 0.1202247177137764, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.4854, \"times_seen\": 23.0}, {\"site\": 277, \"mutant\": \"T\", \"escape\": -0.008011449766265605, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.5363, \"times_seen\": 7.0}, {\"site\": 277, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"280\", \"functional effect\": -0.92, \"times_seen\": null}, {\"site\": 278, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -1.0849, \"times_seen\": null}, {\"site\": 278, \"mutant\": \"A\", \"escape\": 0.005373313079252396, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.0399, \"times_seen\": 6.0}, {\"site\": 278, \"mutant\": \"D\", \"escape\": 0.005707140059711012, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.022, \"times_seen\": 12.0}, {\"site\": 278, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 278, \"mutant\": \"G\", \"escape\": -0.14308294354985468, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.0907, \"times_seen\": 20.0}, {\"site\": 278, \"mutant\": \"K\", \"escape\": -0.0777219583567829, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": -0.0742, \"times_seen\": 66.0}, {\"site\": 278, \"mutant\": \"N\", \"escape\": 0.003083668090890746, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 278, \"mutant\": \"Q\", \"escape\": -0.06172091022037663, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.0644, \"times_seen\": 35.0}, {\"site\": 278, \"mutant\": \"V\", \"escape\": -0.009889772589504906, \"epitope\": \"epitope 1\", \"reference_site\": \"281\", \"functional effect\": 0.1804, \"times_seen\": 3.0}, {\"site\": 279, \"mutant\": \"D\", \"escape\": -0.002703248418762453, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.3515, \"times_seen\": 3.0}, {\"site\": 279, \"mutant\": \"H\", \"escape\": 0.005745192861168056, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": 0.3023, \"times_seen\": 5.0}, {\"site\": 279, \"mutant\": \"I\", \"escape\": -0.0011037072449465095, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.158, \"times_seen\": 6.0}, {\"site\": 279, \"mutant\": \"K\", \"escape\": 0.003946080275510032, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.1816, \"times_seen\": 10.0}, {\"site\": 279, \"mutant\": \"L\", \"escape\": 0.015706715270774083, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.5737, \"times_seen\": 7.0}, {\"site\": 279, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 279, \"mutant\": \"S\", \"escape\": -0.055790462363920414, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.5124, \"times_seen\": 18.0}, {\"site\": 279, \"mutant\": \"T\", \"escape\": 0.0042487876799669495, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.5122, \"times_seen\": 4.0}, {\"site\": 279, \"mutant\": \"Y\", \"escape\": 0.005657519194432677, \"epitope\": \"epitope 1\", \"reference_site\": \"282\", \"functional effect\": -0.3142, \"times_seen\": 6.0}, {\"site\": 280, \"mutant\": \"C\", \"escape\": -0.006109611748717178, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.6094, \"times_seen\": 3.0}, {\"site\": 280, \"mutant\": \"D\", \"escape\": -0.005454427152330024, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.9367, \"times_seen\": 3.0}, {\"site\": 280, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 280, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 280, \"mutant\": \"R\", \"escape\": -0.0109825471019527, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.1027, \"times_seen\": 1.0}, {\"site\": 280, \"mutant\": \"S\", \"escape\": -0.003670466773531214, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -1.1641, \"times_seen\": 11.0}, {\"site\": 280, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 280, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"283\", \"functional effect\": -2.4582, \"times_seen\": null}, {\"site\": 281, \"mutant\": \"A\", \"escape\": 0.10207589622930556, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": -0.3641, \"times_seen\": 9.0}, {\"site\": 281, \"mutant\": \"I\", \"escape\": 0.023424044003552982, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": 0.0723, \"times_seen\": 35.0}, {\"site\": 281, \"mutant\": \"L\", \"escape\": -0.007915122341240737, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": 0.0307, \"times_seen\": 10.0}, {\"site\": 281, \"mutant\": \"N\", \"escape\": -0.025175383470498712, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": -0.7634, \"times_seen\": 15.0}, {\"site\": 281, \"mutant\": \"S\", \"escape\": -0.0025298725531491787, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": -2.1294, \"times_seen\": 1.0}, {\"site\": 281, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"284\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 282, \"mutant\": \"F\", \"escape\": -0.0008494813734468021, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -2.5283, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"H\", \"escape\": -0.002838525383275191, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -0.9999, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 282, \"mutant\": \"L\", \"escape\": 0.010590509062980612, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": 0.3094, \"times_seen\": 2.0}, {\"site\": 282, \"mutant\": \"M\", \"escape\": -0.0024896338206538624, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": 0.0603, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -2.9946, \"times_seen\": null}, {\"site\": 282, \"mutant\": \"T\", \"escape\": -0.0003972745437490745, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -2.4581, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"V\", \"escape\": -0.025556838217757408, \"epitope\": \"epitope 1\", \"reference_site\": \"285\", \"functional effect\": -0.5039, \"times_seen\": 7.0}, {\"site\": 283, \"mutant\": \"A\", \"escape\": -0.0012324532418840465, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.1206, \"times_seen\": 10.0}, {\"site\": 283, \"mutant\": \"I\", \"escape\": -0.08826919480641456, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": -0.2387, \"times_seen\": 42.0}, {\"site\": 283, \"mutant\": \"K\", \"escape\": -0.003637419897282195, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": -0.5709, \"times_seen\": 2.0}, {\"site\": 283, \"mutant\": \"N\", \"escape\": -0.011865638519486636, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.375, \"times_seen\": 6.0}, {\"site\": 283, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.3002, \"times_seen\": null}, {\"site\": 283, \"mutant\": \"S\", \"escape\": -0.013400122409568711, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.0237, \"times_seen\": 5.0}, {\"site\": 283, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 283, \"mutant\": \"Y\", \"escape\": 0.009676109438237183, \"epitope\": \"epitope 1\", \"reference_site\": \"286\", \"functional effect\": -0.7594, \"times_seen\": 5.0}, {\"site\": 284, \"mutant\": \"A\", \"escape\": -0.018091360443852626, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": 0.0436, \"times_seen\": 17.0}, {\"site\": 284, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 284, \"mutant\": \"E\", \"escape\": -0.013513376187283257, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": 0.0117, \"times_seen\": 19.0}, {\"site\": 284, \"mutant\": \"G\", \"escape\": -0.0017479987743836845, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.256, \"times_seen\": 37.0}, {\"site\": 284, \"mutant\": \"H\", \"escape\": -0.5514316193685314, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.5928, \"times_seen\": 21.0}, {\"site\": 284, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.7471, \"times_seen\": null}, {\"site\": 284, \"mutant\": \"N\", \"escape\": 0.18619099344722218, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.2422, \"times_seen\": 42.0}, {\"site\": 284, \"mutant\": \"Q\", \"escape\": 0.002789957900521491, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.1861, \"times_seen\": 5.0}, {\"site\": 284, \"mutant\": \"R\", \"escape\": 0.016482438239308353, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -0.6825, \"times_seen\": 2.0}, {\"site\": 284, \"mutant\": \"V\", \"escape\": -0.007913598653296133, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -2.4039, \"times_seen\": 2.0}, {\"site\": 284, \"mutant\": \"Y\", \"escape\": 0.028432937599206638, \"epitope\": \"epitope 1\", \"reference_site\": \"287\", \"functional effect\": -1.7855, \"times_seen\": 7.0}, {\"site\": 285, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 285, \"mutant\": \"C\", \"escape\": 0.021065305547645703, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -0.3032, \"times_seen\": 10.0}, {\"site\": 285, \"mutant\": \"D\", \"escape\": -0.00029988110891794053, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -1.3855, \"times_seen\": 1.0}, {\"site\": 285, \"mutant\": \"G\", \"escape\": -0.0010987873541680306, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 285, \"mutant\": \"K\", \"escape\": -0.004018536970280076, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -2.0516, \"times_seen\": 1.0}, {\"site\": 285, \"mutant\": \"S\", \"escape\": -0.0072297433499399, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -0.4047, \"times_seen\": 30.0}, {\"site\": 285, \"mutant\": \"T\", \"escape\": -0.13726535247100327, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -0.6318, \"times_seen\": 42.0}, {\"site\": 285, \"mutant\": \"V\", \"escape\": -0.02069734491847258, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": 0.0028, \"times_seen\": 20.0}, {\"site\": 285, \"mutant\": \"Y\", \"escape\": 0.02155604619701787, \"epitope\": \"epitope 1\", \"reference_site\": \"288\", \"functional effect\": -2.377, \"times_seen\": 1.0}, {\"site\": 286, \"mutant\": \"A\", \"escape\": -0.019835848468964686, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -0.9491, \"times_seen\": 11.0}, {\"site\": 286, \"mutant\": \"C\", \"escape\": 0.019535105338667008, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -0.7449, \"times_seen\": 5.0}, {\"site\": 286, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -3.2617, \"times_seen\": null}, {\"site\": 286, \"mutant\": \"I\", \"escape\": 0.006129326278040348, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": 0.0764, \"times_seen\": 46.0}, {\"site\": 286, \"mutant\": \"L\", \"escape\": 0.08004019342634217, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -0.3648, \"times_seen\": 35.0}, {\"site\": 286, \"mutant\": \"M\", \"escape\": -0.009551252277755148, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -2.4112, \"times_seen\": 4.0}, {\"site\": 286, \"mutant\": \"Q\", \"escape\": -0.014445892601434595, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -1.5933, \"times_seen\": 3.0}, {\"site\": 286, \"mutant\": \"R\", \"escape\": -0.0037576577108025906, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -2.7813, \"times_seen\": 1.0}, {\"site\": 286, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": -2.3127, \"times_seen\": null}, {\"site\": 286, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"289\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"C\", \"escape\": -0.0021656404086206863, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.8712, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"E\", \"escape\": -0.0026708307588622455, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"N\", \"escape\": -0.01692842145718036, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.6977, \"times_seen\": 5.0}, {\"site\": 287, \"mutant\": \"R\", \"escape\": -0.00014575029100374166, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -2.4834, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"S\", \"escape\": 0.0012264718098407084, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -1.8107, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -1.8474, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"290\", \"functional effect\": -1.9768, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.8456, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"L\", \"escape\": -0.045410035807514945, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.8773, \"times_seen\": 2.0}, {\"site\": 288, \"mutant\": \"R\", \"escape\": -1.33891425527642, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 288, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.9996, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"Y\", \"escape\": -0.05038741416587932, \"epitope\": \"epitope 1\", \"reference_site\": \"291\", \"functional effect\": -2.942, \"times_seen\": 4.0}, {\"site\": 289, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 289, \"mutant\": \"C\", \"escape\": -0.03496936725798867, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -0.5923, \"times_seen\": 6.0}, {\"site\": 289, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -2.9013, \"times_seen\": null}, {\"site\": 289, \"mutant\": \"G\", \"escape\": -0.020594392566843957, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": 0.0892, \"times_seen\": 21.0}, {\"site\": 289, \"mutant\": \"R\", \"escape\": -0.03561996743225536, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -1.2288, \"times_seen\": 4.0}, {\"site\": 289, \"mutant\": \"S\", \"escape\": -0.015062531548373191, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -0.0029, \"times_seen\": 65.0}, {\"site\": 289, \"mutant\": \"T\", \"escape\": -2.5722047430437103, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -0.4092, \"times_seen\": 99.0}, {\"site\": 289, \"mutant\": \"V\", \"escape\": -0.04841362197528529, \"epitope\": \"epitope 1\", \"reference_site\": \"292\", \"functional effect\": -1.2201, \"times_seen\": 29.0}, {\"site\": 290, \"mutant\": \"F\", \"escape\": 0.00492041466874233, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -0.1435, \"times_seen\": 20.0}, {\"site\": 290, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 290, \"mutant\": \"M\", \"escape\": 0.05206241874873309, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -0.566, \"times_seen\": 18.0}, {\"site\": 290, \"mutant\": \"P\", \"escape\": -0.010258599346497005, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -2.7275, \"times_seen\": 5.0}, {\"site\": 290, \"mutant\": \"Q\", \"escape\": 0.016297416193784726, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 290, \"mutant\": \"R\", \"escape\": 0.013100476061071483, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -1.4644, \"times_seen\": 2.0}, {\"site\": 290, \"mutant\": \"T\", \"escape\": 0.00869963614634991, \"epitope\": \"epitope 1\", \"reference_site\": \"293\", \"functional effect\": -0.4162, \"times_seen\": 4.0}, {\"site\": 291, \"mutant\": \"C\", \"escape\": 0.006985024707455459, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -0.4328, \"times_seen\": 12.0}, {\"site\": 291, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 291, \"mutant\": \"E\", \"escape\": -0.014729410234421661, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -1.797, \"times_seen\": 6.0}, {\"site\": 291, \"mutant\": \"G\", \"escape\": 5.232676653686103e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -0.8142, \"times_seen\": 5.0}, {\"site\": 291, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -2.6269, \"times_seen\": null}, {\"site\": 291, \"mutant\": \"N\", \"escape\": -0.06482816068732777, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -0.7427, \"times_seen\": 15.0}, {\"site\": 291, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"294\", \"functional effect\": -3.032, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -2.9899, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -2.4632, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -3.2361, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"S\", \"escape\": -0.011344401164987142, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -2.5027, \"times_seen\": 4.0}, {\"site\": 292, \"mutant\": \"T\", \"escape\": -0.0037312143568451017, \"epitope\": \"epitope 1\", \"reference_site\": \"295\", \"functional effect\": -1.8602, \"times_seen\": 1.0}, {\"site\": 293, \"mutant\": \"I\", \"escape\": 0.005184013046311864, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -0.0809, \"times_seen\": 7.0}, {\"site\": 293, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 293, \"mutant\": \"M\", \"escape\": -0.0018970607479016056, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -1.0336, \"times_seen\": 6.0}, {\"site\": 293, \"mutant\": \"P\", \"escape\": -0.0031335195968951444, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -1.3293, \"times_seen\": 1.0}, {\"site\": 293, \"mutant\": \"Q\", \"escape\": -0.0022142107069350564, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 293, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -3.268, \"times_seen\": null}, {\"site\": 293, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"296\", \"functional effect\": -2.318, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -2.9573, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"L\", \"escape\": 0.006001804268232447, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -2.9686, \"times_seen\": 4.0}, {\"site\": 294, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -1.8098, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"297\", \"functional effect\": -3.128, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.5392, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -1.1533, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.9724, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"K\", \"escape\": 0.018888305851263023, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.4414, \"times_seen\": 3.0}, {\"site\": 295, \"mutant\": \"Q\", \"escape\": -0.002407630765987767, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.3102, \"times_seen\": 1.0}, {\"site\": 295, \"mutant\": \"R\", \"escape\": 0.008940334213708972, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.7989, \"times_seen\": 4.0}, {\"site\": 295, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"298\", \"functional effect\": -2.5601, \"times_seen\": null}, {\"site\": 296, \"mutant\": \"A\", \"escape\": -0.1170326284623064, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -0.5588, \"times_seen\": 44.0}, {\"site\": 296, \"mutant\": \"I\", \"escape\": -1.4301202885394313, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -0.0909, \"times_seen\": 46.0}, {\"site\": 296, \"mutant\": \"K\", \"escape\": -0.03476522646848175, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -2.6088, \"times_seen\": 1.0}, {\"site\": 296, \"mutant\": \"N\", \"escape\": -0.036966883344656386, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": -2.7361, \"times_seen\": 2.0}, {\"site\": 296, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"299\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -1.2613, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"M\", \"escape\": -0.015974680258547487, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -0.957, \"times_seen\": 8.0}, {\"site\": 297, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -2.7906, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"R\", \"escape\": -0.5267965790945082, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -0.3747, \"times_seen\": 19.0}, {\"site\": 297, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"300\", \"functional effect\": -1.4359, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"E\", \"escape\": -0.289066414583683, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -1.8786, \"times_seen\": 2.0}, {\"site\": 298, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -2.6362, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"R\", \"escape\": -0.008264317487521307, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -1.2026, \"times_seen\": 1.0}, {\"site\": 298, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -2.7258, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"V\", \"escape\": -0.011851028680628128, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -2.9714, \"times_seen\": 1.0}, {\"site\": 298, \"mutant\": \"Y\", \"escape\": -0.02413827318676957, \"epitope\": \"epitope 1\", \"reference_site\": \"301\", \"functional effect\": -1.9379, \"times_seen\": 4.0}, {\"site\": 299, \"mutant\": \"A\", \"escape\": 0.013718385985923249, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -1.499, \"times_seen\": 2.0}, {\"site\": 299, \"mutant\": \"I\", \"escape\": -0.011415286454910537, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -1.3649, \"times_seen\": 2.0}, {\"site\": 299, \"mutant\": \"N\", \"escape\": -7.210938122285038e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -2.7225, \"times_seen\": 1.0}, {\"site\": 299, \"mutant\": \"S\", \"escape\": -0.026513683761398836, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -0.1582, \"times_seen\": 10.0}, {\"site\": 299, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 299, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"302\", \"functional effect\": -2.4022, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"F\", \"escape\": -0.0002549732015042141, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -1.4017, \"times_seen\": 8.0}, {\"site\": 300, \"mutant\": \"I\", \"escape\": -0.0666880735067617, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.2625, \"times_seen\": 11.0}, {\"site\": 300, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"M\", \"escape\": 0.8292994461547425, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.3669, \"times_seen\": 11.0}, {\"site\": 300, \"mutant\": \"P\", \"escape\": 0.017584311442423124, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -2.7576, \"times_seen\": 6.0}, {\"site\": 300, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.1477, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.6929, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"V\", \"escape\": -0.0011184362684991537, \"epitope\": \"epitope 1\", \"reference_site\": \"303\", \"functional effect\": -0.479, \"times_seen\": 3.0}, {\"site\": 301, \"mutant\": \"E\", \"escape\": -0.016231617897943168, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.4159, \"times_seen\": 7.0}, {\"site\": 301, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": -3.2048, \"times_seen\": null}, {\"site\": 301, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 301, \"mutant\": \"N\", \"escape\": -0.014972058132705324, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.2879, \"times_seen\": 6.0}, {\"site\": 301, \"mutant\": \"R\", \"escape\": 0.027950813146321137, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.0628, \"times_seen\": 6.0}, {\"site\": 301, \"mutant\": \"T\", \"escape\": -0.003465726974265556, \"epitope\": \"epitope 1\", \"reference_site\": \"304\", \"functional effect\": 0.158, \"times_seen\": 1.0}, {\"site\": 302, \"mutant\": \"A\", \"escape\": -0.011143737074604802, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -0.1786, \"times_seen\": 3.0}, {\"site\": 302, \"mutant\": \"C\", \"escape\": 0.00823492141556149, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -1.4452, \"times_seen\": 1.0}, {\"site\": 302, \"mutant\": \"F\", \"escape\": -0.0036967477325417805, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -2.3834, \"times_seen\": 1.0}, {\"site\": 302, \"mutant\": \"I\", \"escape\": -0.009111064224921596, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -1.1237, \"times_seen\": 4.0}, {\"site\": 302, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -1.1989, \"times_seen\": null}, {\"site\": 302, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 302, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 302, \"mutant\": \"T\", \"escape\": -0.018136821314128967, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -0.0342, \"times_seen\": 6.0}, {\"site\": 302, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"305\", \"functional effect\": -2.6361, \"times_seen\": null}, {\"site\": 303, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 303, \"mutant\": \"I\", \"escape\": 0.008087171979756804, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -0.6279, \"times_seen\": 1.0}, {\"site\": 303, \"mutant\": \"L\", \"escape\": -0.33365093186888223, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": 0.0613, \"times_seen\": 24.0}, {\"site\": 303, \"mutant\": \"S\", \"escape\": 1.323151542390694, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -1.6708, \"times_seen\": 9.0}, {\"site\": 303, \"mutant\": \"V\", \"escape\": 0.01431098548221548, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -0.909, \"times_seen\": 4.0}, {\"site\": 303, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"306\", \"functional effect\": -2.4926, \"times_seen\": null}, {\"site\": 304, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 304, \"mutant\": \"A\", \"escape\": 0.038325659487285176, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.3108, \"times_seen\": 39.0}, {\"site\": 304, \"mutant\": \"C\", \"escape\": -0.016980517212491143, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -1.2485, \"times_seen\": 14.0}, {\"site\": 304, \"mutant\": \"D\", \"escape\": -0.2340235198733581, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.0379, \"times_seen\": 21.0}, {\"site\": 304, \"mutant\": \"E\", \"escape\": -0.033489091331495795, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1194, \"times_seen\": 21.0}, {\"site\": 304, \"mutant\": \"F\", \"escape\": -0.004605255969772716, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.0637, \"times_seen\": 20.0}, {\"site\": 304, \"mutant\": \"G\", \"escape\": -0.02182092883183537, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.2287, \"times_seen\": 20.0}, {\"site\": 304, \"mutant\": \"H\", \"escape\": 0.17755361043940815, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1652, \"times_seen\": 56.0}, {\"site\": 304, \"mutant\": \"I\", \"escape\": -0.03260846080872745, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1408, \"times_seen\": 65.0}, {\"site\": 304, \"mutant\": \"K\", \"escape\": -0.016643932480774705, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 304, \"mutant\": \"L\", \"escape\": -0.04061550806235745, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.5884, \"times_seen\": 31.0}, {\"site\": 304, \"mutant\": \"M\", \"escape\": 0.028654629376165034, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.2332, \"times_seen\": 14.0}, {\"site\": 304, \"mutant\": \"N\", \"escape\": 0.003018289719944147, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.3637, \"times_seen\": 43.0}, {\"site\": 304, \"mutant\": \"P\", \"escape\": 0.006578371156557748, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -2.9172, \"times_seen\": 5.0}, {\"site\": 304, \"mutant\": \"Q\", \"escape\": -0.023868105500329296, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1465, \"times_seen\": 13.0}, {\"site\": 304, \"mutant\": \"R\", \"escape\": -0.01745669002487412, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.4913, \"times_seen\": 48.0}, {\"site\": 304, \"mutant\": \"S\", \"escape\": -0.3677921470067425, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1091, \"times_seen\": 45.0}, {\"site\": 304, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 304, \"mutant\": \"V\", \"escape\": 0.06932467402048781, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.151, \"times_seen\": 28.0}, {\"site\": 304, \"mutant\": \"W\", \"escape\": 0.007634986576719979, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1403, \"times_seen\": 7.0}, {\"site\": 304, \"mutant\": \"Y\", \"escape\": 0.015608423516030078, \"epitope\": \"epitope 1\", \"reference_site\": \"307\", \"functional effect\": -0.1142, \"times_seen\": 29.0}, {\"site\": 305, \"mutant\": \"A\", \"escape\": -0.006929823213724341, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -3.0197, \"times_seen\": 1.0}, {\"site\": 305, \"mutant\": \"C\", \"escape\": -0.004772888873911419, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -2.9654, \"times_seen\": 1.0}, {\"site\": 305, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -2.9941, \"times_seen\": null}, {\"site\": 305, \"mutant\": \"I\", \"escape\": -0.02818441882552591, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -0.2195, \"times_seen\": 20.0}, {\"site\": 305, \"mutant\": \"L\", \"escape\": -0.41977220126081055, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -0.2644, \"times_seen\": 38.0}, {\"site\": 305, \"mutant\": \"M\", \"escape\": -0.01780125569272437, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": -1.6965, \"times_seen\": 6.0}, {\"site\": 305, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"308\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 306, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -3.0868, \"times_seen\": null}, {\"site\": 306, \"mutant\": \"A\", \"escape\": -0.006389764659375728, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": 0.0088, \"times_seen\": 6.0}, {\"site\": 306, \"mutant\": \"D\", \"escape\": -0.6614947771244443, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": 0.2651, \"times_seen\": 15.0}, {\"site\": 306, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 306, \"mutant\": \"G\", \"escape\": 0.018840552488831014, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.2689, \"times_seen\": 12.0}, {\"site\": 306, \"mutant\": \"K\", \"escape\": 0.1068070074908715, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.3164, \"times_seen\": 43.0}, {\"site\": 306, \"mutant\": \"Q\", \"escape\": -0.010038507536744096, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.3346, \"times_seen\": 10.0}, {\"site\": 306, \"mutant\": \"R\", \"escape\": -0.016636996312255466, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.4373, \"times_seen\": 5.0}, {\"site\": 306, \"mutant\": \"V\", \"escape\": -0.005691543933917956, \"epitope\": \"epitope 1\", \"reference_site\": \"309\", \"functional effect\": -0.4553, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -2.9005, \"times_seen\": null}, {\"site\": 307, \"mutant\": \"E\", \"escape\": 0.0077209895868633575, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -1.2932, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 307, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -2.8108, \"times_seen\": null}, {\"site\": 307, \"mutant\": \"N\", \"escape\": 0.008335490634674205, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -3.1432, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"Q\", \"escape\": 0.004325461723873957, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"R\", \"escape\": 0.8765644579586201, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -0.8163, \"times_seen\": 50.0}, {\"site\": 307, \"mutant\": \"S\", \"escape\": -0.0011501247688139613, \"epitope\": \"epitope 1\", \"reference_site\": \"310\", \"functional effect\": -2.4752, \"times_seen\": 4.0}, {\"site\": 308, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.4876, \"times_seen\": null}, {\"site\": 308, \"mutant\": \"D\", \"escape\": -0.0005862787766063808, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.7756, \"times_seen\": 1.0}, {\"site\": 308, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 308, \"mutant\": \"N\", \"escape\": -0.003983932896992577, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 308, \"mutant\": \"R\", \"escape\": -0.003915837523114841, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -2.9695, \"times_seen\": 2.0}, {\"site\": 308, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -1.6802, \"times_seen\": null}, {\"site\": 308, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"311\", \"functional effect\": -3.1353, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"L\", \"escape\": -0.003545882951359783, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -1.3805, \"times_seen\": 1.0}, {\"site\": 309, \"mutant\": \"M\", \"escape\": 0.012146266949000473, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -0.8374, \"times_seen\": 2.0}, {\"site\": 309, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -0.0493, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -1.8036, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -2.144, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"V\", \"escape\": -0.04202692785575766, \"epitope\": \"epitope 1\", \"reference_site\": \"312\", \"functional effect\": -0.7195, \"times_seen\": 30.0}, {\"site\": 310, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.7744, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -0.4934, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.4895, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"H\", \"escape\": 0.029581305467073445, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -1.1574, \"times_seen\": 18.0}, {\"site\": 310, \"mutant\": \"L\", \"escape\": -0.0016524511285256433, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -1.9558, \"times_seen\": 1.0}, {\"site\": 310, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.942, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.6642, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -2.0463, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": -3.0359, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"313\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -1.2648, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.3253, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"H\", \"escape\": 0.033427022993462584, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": 0.176, \"times_seen\": 23.0}, {\"site\": 311, \"mutant\": \"K\", \"escape\": 1.11488452800592, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.7858, \"times_seen\": 67.0}, {\"site\": 311, \"mutant\": \"L\", \"escape\": -0.026489154014541945, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -1.0693, \"times_seen\": 16.0}, {\"site\": 311, \"mutant\": \"N\", \"escape\": -0.001903044349275535, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -2.9646, \"times_seen\": 1.0}, {\"site\": 311, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"R\", \"escape\": -0.009700821921337791, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.3635, \"times_seen\": 15.0}, {\"site\": 311, \"mutant\": \"T\", \"escape\": -0.6440883756501824, \"epitope\": \"epitope 1\", \"reference_site\": \"314\", \"functional effect\": -0.4081, \"times_seen\": 6.0}, {\"site\": 312, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -2.5656, \"times_seen\": null}, {\"site\": 312, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -2.5653, \"times_seen\": null}, {\"site\": 312, \"mutant\": \"I\", \"escape\": 0.022242262157180573, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -0.6353, \"times_seen\": 53.0}, {\"site\": 312, \"mutant\": \"L\", \"escape\": 0.012738364128519046, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -0.189, \"times_seen\": 6.0}, {\"site\": 312, \"mutant\": \"N\", \"escape\": -0.017713298667806545, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -1.8127, \"times_seen\": 2.0}, {\"site\": 312, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": -2.99, \"times_seen\": null}, {\"site\": 312, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"315\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"A\", \"escape\": 0.6799122510565282, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.3363, \"times_seen\": 6.0}, {\"site\": 313, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.2211, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"F\", \"escape\": -0.0026851608851935285, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -1.5098, \"times_seen\": 17.0}, {\"site\": 313, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.8517, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"I\", \"escape\": -0.003986949282149192, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.2965, \"times_seen\": 1.0}, {\"site\": 313, \"mutant\": \"L\", \"escape\": -0.02932695467768321, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -2.2771, \"times_seen\": 1.0}, {\"site\": 313, \"mutant\": \"N\", \"escape\": -0.08282252888266348, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.6941, \"times_seen\": 34.0}, {\"site\": 313, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -2.6799, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"T\", \"escape\": -0.3134963935923135, \"epitope\": \"epitope 1\", \"reference_site\": \"316\", \"functional effect\": -0.7144, \"times_seen\": 14.0}, {\"site\": 314, \"mutant\": \"D\", \"escape\": -0.020528910470709687, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -0.6442, \"times_seen\": 6.0}, {\"site\": 314, \"mutant\": \"I\", \"escape\": 0.01176620923544312, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -0.6906, \"times_seen\": 15.0}, {\"site\": 314, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -2.3119, \"times_seen\": null}, {\"site\": 314, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 314, \"mutant\": \"S\", \"escape\": 0.08118191863086273, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": 0.397, \"times_seen\": 5.0}, {\"site\": 314, \"mutant\": \"T\", \"escape\": -0.002736206978349796, \"epitope\": \"epitope 1\", \"reference_site\": \"317\", \"functional effect\": -1.267, \"times_seen\": 13.0}, {\"site\": 315, \"mutant\": \"C\", \"escape\": -0.0026946919673309965, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -3.0955, \"times_seen\": 1.0}, {\"site\": 315, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 315, \"mutant\": \"I\", \"escape\": 0.01520241332255794, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -2.3483, \"times_seen\": 3.0}, {\"site\": 315, \"mutant\": \"L\", \"escape\": -0.017434665933770323, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -2.7033, \"times_seen\": 2.0}, {\"site\": 315, \"mutant\": \"S\", \"escape\": 0.007521517383726005, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -1.9318, \"times_seen\": 5.0}, {\"site\": 315, \"mutant\": \"V\", \"escape\": -0.0028190058920459084, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -3.0863, \"times_seen\": 1.0}, {\"site\": 315, \"mutant\": \"Y\", \"escape\": 0.001005584670483022, \"epitope\": \"epitope 1\", \"reference_site\": \"318\", \"functional effect\": -0.6018, \"times_seen\": 6.0}, {\"site\": 316, \"mutant\": \"E\", \"escape\": -0.8920990155814542, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.9537, \"times_seen\": 2.0}, {\"site\": 316, \"mutant\": \"G\", \"escape\": -0.015936176832314193, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.6552, \"times_seen\": 3.0}, {\"site\": 316, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"L\", \"escape\": -0.00981585534680917, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.9195, \"times_seen\": 3.0}, {\"site\": 316, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -3.1273, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"T\", \"escape\": 0.005171226411275952, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.8689, \"times_seen\": 2.0}, {\"site\": 316, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"319\", \"functional effect\": -2.9726, \"times_seen\": null}, {\"site\": 317, \"mutant\": \"A\", \"escape\": -0.026349668313498765, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.7064, \"times_seen\": 10.0}, {\"site\": 317, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -1.9108, \"times_seen\": null}, {\"site\": 317, \"mutant\": \"F\", \"escape\": 0.04557440419923139, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.8559, \"times_seen\": 34.0}, {\"site\": 317, \"mutant\": \"I\", \"escape\": 0.4520718485499902, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.9803, \"times_seen\": 40.0}, {\"site\": 317, \"mutant\": \"L\", \"escape\": 0.002758806139340697, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -1.5735, \"times_seen\": 1.0}, {\"site\": 317, \"mutant\": \"S\", \"escape\": 0.0015424501673434324, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": -0.7449, \"times_seen\": 1.0}, {\"site\": 317, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"320\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 318, \"mutant\": \"*\", \"escape\": -0.00400547100236469, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -2.6762, \"times_seen\": 1.0}, {\"site\": 318, \"mutant\": \"E\", \"escape\": 0.00943241286659339, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.9377, \"times_seen\": 1.0}, {\"site\": 318, \"mutant\": \"H\", \"escape\": -0.02025989432790267, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.5327, \"times_seen\": 10.0}, {\"site\": 318, \"mutant\": \"K\", \"escape\": 0.0071602979890722255, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.8911, \"times_seen\": 9.0}, {\"site\": 318, \"mutant\": \"L\", \"escape\": -0.03802904296215733, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.0811, \"times_seen\": 12.0}, {\"site\": 318, \"mutant\": \"N\", \"escape\": -0.015659672229741795, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.9701, \"times_seen\": 6.0}, {\"site\": 318, \"mutant\": \"P\", \"escape\": 0.001956539269018377, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -1.0749, \"times_seen\": 5.0}, {\"site\": 318, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 318, \"mutant\": \"R\", \"escape\": 0.0029322123839650442, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.2258, \"times_seen\": 8.0}, {\"site\": 318, \"mutant\": \"S\", \"escape\": -0.007292677471596378, \"epitope\": \"epitope 1\", \"reference_site\": \"321\", \"functional effect\": -0.4794, \"times_seen\": 2.0}, {\"site\": 319, \"mutant\": \"A\", \"escape\": 0.03282415470336082, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -0.2729, \"times_seen\": 4.0}, {\"site\": 319, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.9236, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.8881, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.8281, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -3.13, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"S\", \"escape\": 0.0212644511153142, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -1.9086, \"times_seen\": 5.0}, {\"site\": 319, \"mutant\": \"T\", \"escape\": -0.013080075090243568, \"epitope\": \"epitope 1\", \"reference_site\": \"322\", \"functional effect\": -2.2576, \"times_seen\": 4.0}, {\"site\": 320, \"mutant\": \"A\", \"escape\": -0.10496472804887494, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.3162, \"times_seen\": 10.0}, {\"site\": 320, \"mutant\": \"C\", \"escape\": 0.00018427162802658862, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.7671, \"times_seen\": 3.0}, {\"site\": 320, \"mutant\": \"I\", \"escape\": 0.794781285060427, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.4383, \"times_seen\": 60.0}, {\"site\": 320, \"mutant\": \"K\", \"escape\": -0.025732642750539676, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.5786, \"times_seen\": 14.0}, {\"site\": 320, \"mutant\": \"Q\", \"escape\": 0.026260759843460928, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.137, \"times_seen\": 12.0}, {\"site\": 320, \"mutant\": \"R\", \"escape\": -0.008736738363308674, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": -0.6717, \"times_seen\": 5.0}, {\"site\": 320, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"323\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -2.9699, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"A\", \"escape\": -0.014334492666705832, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.1638, \"times_seen\": 5.0}, {\"site\": 321, \"mutant\": \"D\", \"escape\": 0.04444705123359821, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": 0.0029, \"times_seen\": 15.0}, {\"site\": 321, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"G\", \"escape\": -0.016534687387354405, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.3656, \"times_seen\": 7.0}, {\"site\": 321, \"mutant\": \"K\", \"escape\": -0.008575874336135558, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.5403, \"times_seen\": 58.0}, {\"site\": 321, \"mutant\": \"N\", \"escape\": -0.015499838106525592, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.5867, \"times_seen\": 7.0}, {\"site\": 321, \"mutant\": \"Q\", \"escape\": 0.20376744129284075, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.0984, \"times_seen\": 34.0}, {\"site\": 321, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.3572, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"T\", \"escape\": 0.014702474759254739, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.1734, \"times_seen\": 2.0}, {\"site\": 321, \"mutant\": \"V\", \"escape\": 2.6447510935438628e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"324\", \"functional effect\": -0.7978, \"times_seen\": 10.0}, {\"site\": 322, \"mutant\": \"A\", \"escape\": -0.006316676881900063, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.6202, \"times_seen\": 6.0}, {\"site\": 322, \"mutant\": \"F\", \"escape\": 0.0018637026013736259, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -1.2264, \"times_seen\": 15.0}, {\"site\": 322, \"mutant\": \"G\", \"escape\": -0.014205544979382053, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.7689, \"times_seen\": 2.0}, {\"site\": 322, \"mutant\": \"I\", \"escape\": -0.009767935746022773, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -2.213, \"times_seen\": 3.0}, {\"site\": 322, \"mutant\": \"L\", \"escape\": -0.005270281047637757, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -1.5172, \"times_seen\": 2.0}, {\"site\": 322, \"mutant\": \"N\", \"escape\": -0.051066510546251775, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.3715, \"times_seen\": 21.0}, {\"site\": 322, \"mutant\": \"R\", \"escape\": 0.009077288541616227, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.9655, \"times_seen\": 12.0}, {\"site\": 322, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 322, \"mutant\": \"Y\", \"escape\": -0.064129510067772, \"epitope\": \"epitope 1\", \"reference_site\": \"325\", \"functional effect\": -0.9614, \"times_seen\": 8.0}, {\"site\": 323, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -3.2614, \"times_seen\": null}, {\"site\": 323, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 323, \"mutant\": \"L\", \"escape\": 0.025484497749436508, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -1.4178, \"times_seen\": 1.0}, {\"site\": 323, \"mutant\": \"M\", \"escape\": 0.0053950302409917685, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -1.7148, \"times_seen\": 1.0}, {\"site\": 323, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -3.1291, \"times_seen\": null}, {\"site\": 323, \"mutant\": \"T\", \"escape\": -0.023909357271045026, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -1.0998, \"times_seen\": 1.0}, {\"site\": 323, \"mutant\": \"V\", \"escape\": 0.627144422466649, \"epitope\": \"epitope 1\", \"reference_site\": \"326\", \"functional effect\": -0.3931, \"times_seen\": 9.0}, {\"site\": 324, \"mutant\": \"A\", \"escape\": 0.0011897482741607213, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.7275, \"times_seen\": 3.0}, {\"site\": 324, \"mutant\": \"C\", \"escape\": -0.0036803568560063366, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -2.6838, \"times_seen\": 2.0}, {\"site\": 324, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -1.6056, \"times_seen\": null}, {\"site\": 324, \"mutant\": \"F\", \"escape\": -0.004869142515298993, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -1.3291, \"times_seen\": 3.0}, {\"site\": 324, \"mutant\": \"I\", \"escape\": -0.44014969667284193, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.1757, \"times_seen\": 21.0}, {\"site\": 324, \"mutant\": \"L\", \"escape\": 0.0012725646202889872, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.3755, \"times_seen\": 11.0}, {\"site\": 324, \"mutant\": \"M\", \"escape\": 0.029286814386310762, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.9679, \"times_seen\": 6.0}, {\"site\": 324, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 324, \"mutant\": \"Y\", \"escape\": -0.013320231567617476, \"epitope\": \"epitope 1\", \"reference_site\": \"327\", \"functional effect\": -0.8286, \"times_seen\": 4.0}, {\"site\": 325, \"mutant\": \"C\", \"escape\": -0.01398065885335652, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.836, \"times_seen\": 2.0}, {\"site\": 325, \"mutant\": \"D\", \"escape\": -0.009699448634076324, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.8843, \"times_seen\": 2.0}, {\"site\": 325, \"mutant\": \"G\", \"escape\": -0.008447784759958589, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.1289, \"times_seen\": 3.0}, {\"site\": 325, \"mutant\": \"K\", \"escape\": -0.0020851582914113184, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.6076, \"times_seen\": 5.0}, {\"site\": 325, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.9665, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.6845, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"S\", \"escape\": -0.003976110262368076, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.5307, \"times_seen\": 1.0}, {\"site\": 325, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -1.2725, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"328\", \"functional effect\": -2.0587, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -3.0183, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"I\", \"escape\": 0.018960671096218684, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -1.4592, \"times_seen\": 4.0}, {\"site\": 326, \"mutant\": \"L\", \"escape\": 0.009824918563864896, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -0.6351, \"times_seen\": 3.0}, {\"site\": 326, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"V\", \"escape\": -0.0005125843522397665, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -0.4705, \"times_seen\": 1.0}, {\"site\": 326, \"mutant\": \"Y\", \"escape\": -0.003665887164814847, \"epitope\": \"epitope 1\", \"reference_site\": \"329\", \"functional effect\": -0.0063, \"times_seen\": 2.0}, {\"site\": 327, \"mutant\": \"A\", \"escape\": 0.008272999045234429, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -0.7972, \"times_seen\": 3.0}, {\"site\": 327, \"mutant\": \"G\", \"escape\": -0.006779332122633932, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -2.3054, \"times_seen\": 2.0}, {\"site\": 327, \"mutant\": \"L\", \"escape\": -0.03266633193542283, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -2.0515, \"times_seen\": 13.0}, {\"site\": 327, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 327, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -2.5724, \"times_seen\": null}, {\"site\": 327, \"mutant\": \"S\", \"escape\": -0.012343004656069086, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -0.7268, \"times_seen\": 9.0}, {\"site\": 327, \"mutant\": \"T\", \"escape\": -0.02866658566587562, \"epitope\": \"epitope 1\", \"reference_site\": \"330\", \"functional effect\": -0.5332, \"times_seen\": 8.0}, {\"site\": 328, \"mutant\": \"D\", \"escape\": -0.02912391236565673, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.6479, \"times_seen\": 7.0}, {\"site\": 328, \"mutant\": \"E\", \"escape\": -0.03516452563026219, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.8157, \"times_seen\": 6.0}, {\"site\": 328, \"mutant\": \"H\", \"escape\": -0.020440001486970012, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.4035, \"times_seen\": 4.0}, {\"site\": 328, \"mutant\": \"I\", \"escape\": -0.02857266802702702, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.5622, \"times_seen\": 9.0}, {\"site\": 328, \"mutant\": \"K\", \"escape\": 0.000121732420344342, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.3715, \"times_seen\": 2.0}, {\"site\": 328, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 328, \"mutant\": \"S\", \"escape\": -0.026294854500445386, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.8968, \"times_seen\": 10.0}, {\"site\": 328, \"mutant\": \"T\", \"escape\": -0.006832286036391599, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -1.143, \"times_seen\": 2.0}, {\"site\": 328, \"mutant\": \"Y\", \"escape\": -0.0022589370405649224, \"epitope\": \"epitope 1\", \"reference_site\": \"331\", \"functional effect\": -0.7836, \"times_seen\": 6.0}, {\"site\": 329, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -0.3912, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -1.7635, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": 0.087, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"N\", \"escape\": 0.0011255579065463056, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -1.0754, \"times_seen\": 2.0}, {\"site\": 329, \"mutant\": \"T\", \"escape\": -0.0024314791121930308, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -0.7585, \"times_seen\": 8.0}, {\"site\": 329, \"mutant\": \"V\", \"escape\": 0.008333647261260482, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": -0.3776, \"times_seen\": 8.0}, {\"site\": 329, \"mutant\": \"Y\", \"escape\": -0.016160553742630687, \"epitope\": \"epitope 1\", \"reference_site\": \"332\", \"functional effect\": 0.2852, \"times_seen\": 11.0}, {\"site\": 330, \"mutant\": \"A\", \"escape\": 0.2767396250076436, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.7535, \"times_seen\": 12.0}, {\"site\": 330, \"mutant\": \"F\", \"escape\": 0.012714262925521183, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.5184, \"times_seen\": 2.0}, {\"site\": 330, \"mutant\": \"I\", \"escape\": -0.04567867226764466, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.1133, \"times_seen\": 19.0}, {\"site\": 330, \"mutant\": \"K\", \"escape\": -0.026691165251656226, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.5261, \"times_seen\": 6.0}, {\"site\": 330, \"mutant\": \"L\", \"escape\": -0.0070075425798281875, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.2929, \"times_seen\": 3.0}, {\"site\": 330, \"mutant\": \"N\", \"escape\": -0.017237911195432623, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.6052, \"times_seen\": 3.0}, {\"site\": 330, \"mutant\": \"P\", \"escape\": -0.017701931602566688, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -0.9414, \"times_seen\": 13.0}, {\"site\": 330, \"mutant\": \"S\", \"escape\": -0.0019281686614721117, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": 0.1851, \"times_seen\": 1.0}, {\"site\": 330, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 330, \"mutant\": \"Y\", \"escape\": -0.024458796909202454, \"epitope\": \"epitope 1\", \"reference_site\": \"333\", \"functional effect\": -1.0236, \"times_seen\": 9.0}, {\"site\": 331, \"mutant\": \"D\", \"escape\": -0.015916292503464716, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.1305, \"times_seen\": 5.0}, {\"site\": 331, \"mutant\": \"H\", \"escape\": -0.0048132846963475796, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -0.3008, \"times_seen\": 10.0}, {\"site\": 331, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -1.0289, \"times_seen\": null}, {\"site\": 331, \"mutant\": \"K\", \"escape\": -0.05674726916377153, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -0.0467, \"times_seen\": 13.0}, {\"site\": 331, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 331, \"mutant\": \"Q\", \"escape\": -0.012182313666094168, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 331, \"mutant\": \"S\", \"escape\": -0.025232351008071283, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": 0.1552, \"times_seen\": 9.0}, {\"site\": 331, \"mutant\": \"Y\", \"escape\": -0.08642225891759879, \"epitope\": \"epitope 1\", \"reference_site\": \"334\", \"functional effect\": -0.6434, \"times_seen\": 15.0}, {\"site\": 332, \"mutant\": \"A\", \"escape\": -0.030064625853636968, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.1562, \"times_seen\": 6.0}, {\"site\": 332, \"mutant\": \"F\", \"escape\": 0.013363249153359695, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.5329, \"times_seen\": 11.0}, {\"site\": 332, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 332, \"mutant\": \"M\", \"escape\": 0.009744660870631677, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.1499, \"times_seen\": 2.0}, {\"site\": 332, \"mutant\": \"P\", \"escape\": -0.03822477846750899, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.3107, \"times_seen\": 44.0}, {\"site\": 332, \"mutant\": \"Q\", \"escape\": -0.0031589637154249136, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 332, \"mutant\": \"R\", \"escape\": 0.0002912497479504286, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.1127, \"times_seen\": 3.0}, {\"site\": 332, \"mutant\": \"S\", \"escape\": 0.021839577833166937, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.1485, \"times_seen\": 4.0}, {\"site\": 332, \"mutant\": \"T\", \"escape\": -0.002796237946173798, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": -0.1033, \"times_seen\": 5.0}, {\"site\": 332, \"mutant\": \"V\", \"escape\": -0.036876906686341915, \"epitope\": \"epitope 1\", \"reference_site\": \"335\", \"functional effect\": 0.1043, \"times_seen\": 10.0}, {\"site\": 333, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -1.984, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -2.0218, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -2.8487, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"S\", \"escape\": -0.0018654944746970916, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -3.0902, \"times_seen\": 1.0}, {\"site\": 333, \"mutant\": \"T\", \"escape\": -0.003557859316690387, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -0.5053, \"times_seen\": 1.0}, {\"site\": 333, \"mutant\": \"V\", \"escape\": -0.002785324808780706, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -3.0351, \"times_seen\": 1.0}, {\"site\": 333, \"mutant\": \"Y\", \"escape\": -0.0021215747957485796, \"epitope\": \"epitope 1\", \"reference_site\": \"336\", \"functional effect\": -3.0805, \"times_seen\": 1.0}, {\"site\": 334, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.4448, \"times_seen\": null}, {\"site\": 334, \"mutant\": \"H\", \"escape\": 0.014154383995678406, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.5521, \"times_seen\": 7.0}, {\"site\": 334, \"mutant\": \"L\", \"escape\": 0.04113858027354484, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -1.2878, \"times_seen\": 24.0}, {\"site\": 334, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 334, \"mutant\": \"Q\", \"escape\": -0.020545375258078688, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.5949, \"times_seen\": 5.0}, {\"site\": 334, \"mutant\": \"R\", \"escape\": 0.025223112409330742, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.0135, \"times_seen\": 4.0}, {\"site\": 334, \"mutant\": \"S\", \"escape\": -0.02161194452990745, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.2692, \"times_seen\": 29.0}, {\"site\": 334, \"mutant\": \"T\", \"escape\": -0.04761689622290248, \"epitope\": \"epitope 1\", \"reference_site\": \"337\", \"functional effect\": -0.9523, \"times_seen\": 26.0}, {\"site\": 335, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.8826, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"I\", \"escape\": 0.00295338234181275, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -1.541, \"times_seen\": 1.0}, {\"site\": 335, \"mutant\": \"L\", \"escape\": 0.13247908931633204, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -0.2003, \"times_seen\": 16.0}, {\"site\": 335, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.9682, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"338\", \"functional effect\": -2.6032, \"times_seen\": null}, {\"site\": 336, \"mutant\": \"*\", \"escape\": -0.005530314927369015, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -2.9687, \"times_seen\": 2.0}, {\"site\": 336, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 336, \"mutant\": \"A\", \"escape\": 0.3046488988528339, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.0839, \"times_seen\": 90.0}, {\"site\": 336, \"mutant\": \"C\", \"escape\": -0.027320646061659917, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -2.0663, \"times_seen\": 14.0}, {\"site\": 336, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 336, \"mutant\": \"E\", \"escape\": -0.3968903991516656, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1538, \"times_seen\": 47.0}, {\"site\": 336, \"mutant\": \"F\", \"escape\": -0.14147337219536124, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.3194, \"times_seen\": 20.0}, {\"site\": 336, \"mutant\": \"G\", \"escape\": -0.41459632294228016, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2671, \"times_seen\": 97.0}, {\"site\": 336, \"mutant\": \"H\", \"escape\": 0.0037536561121197147, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1039, \"times_seen\": 23.0}, {\"site\": 336, \"mutant\": \"I\", \"escape\": 0.372177740789291, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.0518, \"times_seen\": 28.0}, {\"site\": 336, \"mutant\": \"K\", \"escape\": 0.081359665679391, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2848, \"times_seen\": 20.0}, {\"site\": 336, \"mutant\": \"L\", \"escape\": 0.18717795201367185, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1498, \"times_seen\": 72.0}, {\"site\": 336, \"mutant\": \"M\", \"escape\": -0.04214724721426815, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.024, \"times_seen\": 19.0}, {\"site\": 336, \"mutant\": \"N\", \"escape\": 0.28676906468305113, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.1268, \"times_seen\": 37.0}, {\"site\": 336, \"mutant\": \"P\", \"escape\": -0.00035345021074872625, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.5614, \"times_seen\": 56.0}, {\"site\": 336, \"mutant\": \"Q\", \"escape\": 0.021886549863669027, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.0728, \"times_seen\": 24.0}, {\"site\": 336, \"mutant\": \"R\", \"escape\": -0.3207274400756798, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2837, \"times_seen\": 60.0}, {\"site\": 336, \"mutant\": \"S\", \"escape\": 0.19349601844149528, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.143, \"times_seen\": 99.0}, {\"site\": 336, \"mutant\": \"T\", \"escape\": 0.8546804655643844, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.0781, \"times_seen\": 62.0}, {\"site\": 336, \"mutant\": \"V\", \"escape\": -0.08426466830419674, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.1474, \"times_seen\": 83.0}, {\"site\": 336, \"mutant\": \"W\", \"escape\": 0.48412522824879034, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": 0.011, \"times_seen\": 32.0}, {\"site\": 336, \"mutant\": \"Y\", \"escape\": -0.08922382748233222, \"epitope\": \"epitope 1\", \"reference_site\": \"339\", \"functional effect\": -0.2646, \"times_seen\": 30.0}, {\"site\": 337, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 337, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 337, \"mutant\": \"A\", \"escape\": -0.008041869639351084, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.5449, \"times_seen\": 10.0}, {\"site\": 337, \"mutant\": \"D\", \"escape\": -0.10959395707276759, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.3, \"times_seen\": 42.0}, {\"site\": 337, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 337, \"mutant\": \"G\", \"escape\": -0.007385913335546571, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -1.2106, \"times_seen\": 11.0}, {\"site\": 337, \"mutant\": \"K\", \"escape\": 0.059159317836595074, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.3866, \"times_seen\": 82.0}, {\"site\": 337, \"mutant\": \"Q\", \"escape\": -0.027660792241311537, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.4231, \"times_seen\": 22.0}, {\"site\": 337, \"mutant\": \"S\", \"escape\": -0.038029202440332005, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.356, \"times_seen\": 13.0}, {\"site\": 337, \"mutant\": \"V\", \"escape\": -0.01101520153429878, \"epitope\": \"epitope 1\", \"reference_site\": \"340\", \"functional effect\": -0.9399, \"times_seen\": 10.0}, {\"site\": 338, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -2.9882, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"F\", \"escape\": 0.005218969319557844, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -0.1591, \"times_seen\": 9.0}, {\"site\": 338, \"mutant\": \"I\", \"escape\": -0.02100846555849651, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": 0.2472, \"times_seen\": 25.0}, {\"site\": 338, \"mutant\": \"L\", \"escape\": -0.00710460132775888, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": 0.2113, \"times_seen\": 5.0}, {\"site\": 338, \"mutant\": \"M\", \"escape\": -0.04068418700131312, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -0.6083, \"times_seen\": 9.0}, {\"site\": 338, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": -3.0848, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"341\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.879, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"L\", \"escape\": -0.03482700779838051, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -0.9156, \"times_seen\": 26.0}, {\"site\": 339, \"mutant\": \"S\", \"escape\": -0.007972365617273958, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.5995, \"times_seen\": 1.0}, {\"site\": 339, \"mutant\": \"Y\", \"escape\": -0.015043317786877041, \"epitope\": \"epitope 1\", \"reference_site\": \"342\", \"functional effect\": -2.1252, \"times_seen\": 4.0}, {\"site\": 340, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"D\", \"escape\": -0.06206028272451173, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -2.1705, \"times_seen\": 5.0}, {\"site\": 340, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -3.2684, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"K\", \"escape\": -0.0006875802575552506, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -1.0153, \"times_seen\": 6.0}, {\"site\": 340, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"S\", \"escape\": -0.015454487420015565, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -1.1804, \"times_seen\": 9.0}, {\"site\": 340, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -2.0563, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"Y\", \"escape\": 0.01026495739828772, \"epitope\": \"epitope 1\", \"reference_site\": \"343\", \"functional effect\": -1.4042, \"times_seen\": 4.0}, {\"site\": 341, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 341, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 341, \"mutant\": \"D\", \"escape\": -0.01987257367761145, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -1.243, \"times_seen\": 8.0}, {\"site\": 341, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -2.5035, \"times_seen\": null}, {\"site\": 341, \"mutant\": \"R\", \"escape\": -0.007945137216616898, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.3353, \"times_seen\": 7.0}, {\"site\": 341, \"mutant\": \"S\", \"escape\": -0.04019258668343564, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.2672, \"times_seen\": 36.0}, {\"site\": 341, \"mutant\": \"T\", \"escape\": -0.017534364832326996, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.5728, \"times_seen\": 65.0}, {\"site\": 341, \"mutant\": \"V\", \"escape\": -0.03421758800265016, \"epitope\": \"epitope 1\", \"reference_site\": \"344\", \"functional effect\": -0.4456, \"times_seen\": 42.0}, {\"site\": 342, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 342, \"mutant\": \"H\", \"escape\": -0.01859015000143012, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -0.6463, \"times_seen\": 5.0}, {\"site\": 342, \"mutant\": \"I\", \"escape\": -0.00658447285540281, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -1.1581, \"times_seen\": 2.0}, {\"site\": 342, \"mutant\": \"N\", \"escape\": -0.007548977706962125, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -2.2256, \"times_seen\": 3.0}, {\"site\": 342, \"mutant\": \"S\", \"escape\": -0.012698437914518646, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": -0.1618, \"times_seen\": 16.0}, {\"site\": 342, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"345\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 343, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 343, \"mutant\": \"G\", \"escape\": -0.16852440786448286, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.8701, \"times_seen\": 13.0}, {\"site\": 343, \"mutant\": \"I\", \"escape\": -1.410995022034591, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.1825, \"times_seen\": 38.0}, {\"site\": 343, \"mutant\": \"K\", \"escape\": 0.29370587062991244, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": 0.0144, \"times_seen\": 40.0}, {\"site\": 343, \"mutant\": \"M\", \"escape\": 0.0022800403447255906, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.433, \"times_seen\": 3.0}, {\"site\": 343, \"mutant\": \"Q\", \"escape\": -0.5940538839867843, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.0793, \"times_seen\": 21.0}, {\"site\": 343, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 343, \"mutant\": \"S\", \"escape\": -1.7488361524356677, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.0179, \"times_seen\": 36.0}, {\"site\": 343, \"mutant\": \"T\", \"escape\": -0.008198909217082412, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -0.0394, \"times_seen\": 46.0}, {\"site\": 343, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"346\", \"functional effect\": -1.4097, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"C\", \"escape\": 0.018906604234946212, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.9264, \"times_seen\": 1.0}, {\"site\": 345, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.6967, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"E\", \"escape\": 0.02014285644181749, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -1.2666, \"times_seen\": 11.0}, {\"site\": 345, \"mutant\": \"G\", \"escape\": 0.001037318868065635, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -0.8318, \"times_seen\": 1.0}, {\"site\": 345, \"mutant\": \"L\", \"escape\": -0.007786968508752481, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.7247, \"times_seen\": 1.0}, {\"site\": 345, \"mutant\": \"P\", \"escape\": 0.005317059998955807, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": 0.286, \"times_seen\": 15.0}, {\"site\": 345, \"mutant\": \"S\", \"escape\": -0.089991827283263, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -0.1404, \"times_seen\": 54.0}, {\"site\": 345, \"mutant\": \"T\", \"escape\": -0.037150079871415026, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -1.4223, \"times_seen\": 66.0}, {\"site\": 345, \"mutant\": \"V\", \"escape\": 0.047149808196496716, \"epitope\": \"epitope 1\", \"reference_site\": \"348\", \"functional effect\": -2.0791, \"times_seen\": 18.0}, {\"site\": 346, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"A\", \"escape\": 0.03707306646661316, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.3199, \"times_seen\": 7.0}, {\"site\": 346, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.9226, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"L\", \"escape\": -0.0034936799513035416, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.6787, \"times_seen\": 1.0}, {\"site\": 346, \"mutant\": \"P\", \"escape\": -0.013927868698911064, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -0.9486, \"times_seen\": 42.0}, {\"site\": 346, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.9673, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"349\", \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -1.3334, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"A\", \"escape\": 0.00621680207913282, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.7213, \"times_seen\": 6.0}, {\"site\": 347, \"mutant\": \"C\", \"escape\": -0.0019038235324690153, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.8082, \"times_seen\": 1.0}, {\"site\": 347, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"F\", \"escape\": -0.005447532390982027, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 347, \"mutant\": \"I\", \"escape\": -0.01209990520036336, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.448, \"times_seen\": 3.0}, {\"site\": 347, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": -2.9322, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"350\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -2.1682, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -2.0452, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -3.2547, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"F\", \"escape\": -0.007984059623905474, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -0.2001, \"times_seen\": 8.0}, {\"site\": 348, \"mutant\": \"H\", \"escape\": -0.7018358455167014, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -1.3139, \"times_seen\": 36.0}, {\"site\": 348, \"mutant\": \"L\", \"escape\": 0.012970838535030681, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -1.8702, \"times_seen\": 2.0}, {\"site\": 348, \"mutant\": \"M\", \"escape\": 0.009218100110054715, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -1.7304, \"times_seen\": 2.0}, {\"site\": 348, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": -2.7372, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"351\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -2.7571, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"C\", \"escape\": 0.017014691822193506, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -1.6949, \"times_seen\": 5.0}, {\"site\": 349, \"mutant\": \"D\", \"escape\": -0.00992272114675866, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -1.3905, \"times_seen\": 4.0}, {\"site\": 349, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"M\", \"escape\": -0.011481257603787163, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -0.151, \"times_seen\": 3.0}, {\"site\": 349, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"S\", \"escape\": -0.13056831632239216, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -0.3134, \"times_seen\": 29.0}, {\"site\": 349, \"mutant\": \"T\", \"escape\": -0.03875181237095773, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -1.7921, \"times_seen\": 11.0}, {\"site\": 349, \"mutant\": \"V\", \"escape\": -0.03634264235168769, \"epitope\": \"epitope 1\", \"reference_site\": \"352\", \"functional effect\": -2.0636, \"times_seen\": 12.0}, {\"site\": 350, \"mutant\": \"*\", \"escape\": -0.012000987365578471, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -2.6704, \"times_seen\": 14.0}, {\"site\": 350, \"mutant\": \"C\", \"escape\": -0.015256595821632371, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -1.6642, \"times_seen\": 4.0}, {\"site\": 350, \"mutant\": \"F\", \"escape\": -0.003797324849142484, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -1.2602, \"times_seen\": 3.0}, {\"site\": 350, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -2.7008, \"times_seen\": null}, {\"site\": 350, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -0.759, \"times_seen\": null}, {\"site\": 350, \"mutant\": \"R\", \"escape\": -0.007953830090221648, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": -2.2285, \"times_seen\": 4.0}, {\"site\": 350, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"353\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 351, \"mutant\": \"D\", \"escape\": 0.1766075051701242, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.0623, \"times_seen\": 14.0}, {\"site\": 351, \"mutant\": \"E\", \"escape\": -0.002973834205169647, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.147, \"times_seen\": 2.0}, {\"site\": 351, \"mutant\": \"G\", \"escape\": -0.0026512501852792815, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.4126, \"times_seen\": 1.0}, {\"site\": 351, \"mutant\": \"H\", \"escape\": -0.00951411840597063, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.0631, \"times_seen\": 23.0}, {\"site\": 351, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.3727, \"times_seen\": null}, {\"site\": 351, \"mutant\": \"K\", \"escape\": 0.7150765368186264, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.0079, \"times_seen\": 37.0}, {\"site\": 351, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 351, \"mutant\": \"S\", \"escape\": 0.06723041063649368, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -0.0514, \"times_seen\": 17.0}, {\"site\": 351, \"mutant\": \"T\", \"escape\": -0.015534943527536132, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": 0.0793, \"times_seen\": 12.0}, {\"site\": 351, \"mutant\": \"Y\", \"escape\": -0.0032154271060542278, \"epitope\": \"epitope 1\", \"reference_site\": \"354\", \"functional effect\": -1.1562, \"times_seen\": 9.0}, {\"site\": 352, \"mutant\": \"G\", \"escape\": -0.1313097717114885, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.9596, \"times_seen\": 2.0}, {\"site\": 352, \"mutant\": \"K\", \"escape\": -0.00989139327718863, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.7349, \"times_seen\": 2.0}, {\"site\": 352, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -3.0142, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.9914, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.6016, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"T\", \"escape\": -0.005611965770370521, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.9759, \"times_seen\": 1.0}, {\"site\": 352, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"355\", \"functional effect\": -2.7663, \"times_seen\": null}, {\"site\": 353, \"mutant\": \"E\", \"escape\": -0.0018241238916978553, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -0.879, \"times_seen\": 8.0}, {\"site\": 353, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -2.6337, \"times_seen\": null}, {\"site\": 353, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 353, \"mutant\": \"M\", \"escape\": -0.02662949512619205, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.0611, \"times_seen\": 16.0}, {\"site\": 353, \"mutant\": \"N\", \"escape\": -0.15480579328042784, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -0.716, \"times_seen\": 43.0}, {\"site\": 353, \"mutant\": \"Q\", \"escape\": -0.006213025364248908, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.1857, \"times_seen\": 6.0}, {\"site\": 353, \"mutant\": \"R\", \"escape\": 0.19619422017777735, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": -0.0135, \"times_seen\": 63.0}, {\"site\": 353, \"mutant\": \"T\", \"escape\": -0.24983624577849628, \"epitope\": \"epitope 1\", \"reference_site\": \"356\", \"functional effect\": 0.1867, \"times_seen\": 5.0}, {\"site\": 354, \"mutant\": \"E\", \"escape\": -0.05368602844576032, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.5066, \"times_seen\": 8.0}, {\"site\": 354, \"mutant\": \"G\", \"escape\": -0.7132930897162904, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -1.2627, \"times_seen\": 12.0}, {\"site\": 354, \"mutant\": \"I\", \"escape\": -0.025892574458642147, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": 0.0912, \"times_seen\": 8.0}, {\"site\": 354, \"mutant\": \"K\", \"escape\": 0.028551021546973716, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": 0.1788, \"times_seen\": 61.0}, {\"site\": 354, \"mutant\": \"M\", \"escape\": -0.0121208980114302, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.1804, \"times_seen\": 9.0}, {\"site\": 354, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 354, \"mutant\": \"S\", \"escape\": -0.026030251779749936, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.1978, \"times_seen\": 6.0}, {\"site\": 354, \"mutant\": \"T\", \"escape\": -0.006475597398903156, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -0.0626, \"times_seen\": 1.0}, {\"site\": 354, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"357\", \"functional effect\": -1.6586, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"E\", \"escape\": -0.0035751343485829995, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -2.5714, \"times_seen\": 1.0}, {\"site\": 355, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"L\", \"escape\": 0.023781888431568907, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -0.1098, \"times_seen\": 5.0}, {\"site\": 355, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -1.5589, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"N\", \"escape\": -0.015147056620277292, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -2.9698, \"times_seen\": 1.0}, {\"site\": 355, \"mutant\": \"S\", \"escape\": -0.003280829518957438, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -2.0747, \"times_seen\": 1.0}, {\"site\": 355, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -3.2049, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"V\", \"escape\": -0.014894723417298973, \"epitope\": \"epitope 1\", \"reference_site\": \"358\", \"functional effect\": -1.0623, \"times_seen\": 5.0}, {\"site\": 356, \"mutant\": \"A\", \"escape\": -0.010094129545044394, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 356, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.9389, \"times_seen\": null}, {\"site\": 356, \"mutant\": \"G\", \"escape\": -0.05416686389581966, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -1.0958, \"times_seen\": 40.0}, {\"site\": 356, \"mutant\": \"I\", \"escape\": -0.09889274896083587, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.7569, \"times_seen\": 17.0}, {\"site\": 356, \"mutant\": \"L\", \"escape\": -0.0037945287004649626, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -1.8765, \"times_seen\": 1.0}, {\"site\": 356, \"mutant\": \"N\", \"escape\": -0.14273229466663545, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.2229, \"times_seen\": 57.0}, {\"site\": 356, \"mutant\": \"R\", \"escape\": -0.05953439257036347, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.2929, \"times_seen\": 38.0}, {\"site\": 356, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 356, \"mutant\": \"T\", \"escape\": -0.31539926282605557, \"epitope\": \"epitope 1\", \"reference_site\": \"359\", \"functional effect\": -0.1307, \"times_seen\": 15.0}, {\"site\": 357, \"mutant\": \"A\", \"escape\": -0.012585946175447985, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -1.1934, \"times_seen\": 3.0}, {\"site\": 357, \"mutant\": \"D\", \"escape\": -0.051411065987971044, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": 0.1485, \"times_seen\": 20.0}, {\"site\": 357, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 357, \"mutant\": \"K\", \"escape\": 0.006042706028861773, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -1.5839, \"times_seen\": 9.0}, {\"site\": 357, \"mutant\": \"L\", \"escape\": -0.010224133193472087, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -2.5769, \"times_seen\": 1.0}, {\"site\": 357, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 357, \"mutant\": \"S\", \"escape\": -0.009940941394662638, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -0.6761, \"times_seen\": 10.0}, {\"site\": 357, \"mutant\": \"T\", \"escape\": -0.005011392765188626, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -2.6163, \"times_seen\": 8.0}, {\"site\": 357, \"mutant\": \"Y\", \"escape\": -0.023261633735054167, \"epitope\": \"epitope 1\", \"reference_site\": \"360\", \"functional effect\": -0.9013, \"times_seen\": 11.0}, {\"site\": 358, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.1294, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"F\", \"escape\": 0.011497447991888496, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.0623, \"times_seen\": 1.0}, {\"site\": 358, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.2653, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.1037, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"R\", \"escape\": -0.11912403984114102, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -3.0611, \"times_seen\": 2.0}, {\"site\": 358, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.8591, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.9714, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"V\", \"escape\": 0.5864190682223993, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.0774, \"times_seen\": 2.0}, {\"site\": 358, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"361\", \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 359, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 359, \"mutant\": \"A\", \"escape\": -0.0035940656384100254, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -1.5445, \"times_seen\": 1.0}, {\"site\": 359, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -2.8474, \"times_seen\": null}, {\"site\": 359, \"mutant\": \"F\", \"escape\": -0.022187182672424817, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -2.0064, \"times_seen\": 8.0}, {\"site\": 359, \"mutant\": \"I\", \"escape\": -0.004195728739956035, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": 0.3073, \"times_seen\": 19.0}, {\"site\": 359, \"mutant\": \"L\", \"escape\": -0.024232670591152042, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -0.6073, \"times_seen\": 8.0}, {\"site\": 359, \"mutant\": \"M\", \"escape\": -0.031948886537225295, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": -0.4763, \"times_seen\": 9.0}, {\"site\": 359, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"362\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 360, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 360, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 360, \"mutant\": \"D\", \"escape\": -0.007836744243860242, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 360, \"mutant\": \"L\", \"escape\": -0.015029726345631976, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": 0.1011, \"times_seen\": 4.0}, {\"site\": 360, \"mutant\": \"S\", \"escape\": -0.026326122598990594, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -0.5295, \"times_seen\": 7.0}, {\"site\": 360, \"mutant\": \"T\", \"escape\": -0.09807222868327185, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -0.8575, \"times_seen\": 30.0}, {\"site\": 360, \"mutant\": \"V\", \"escape\": -1.0721450766808003, \"epitope\": \"epitope 1\", \"reference_site\": \"363\", \"functional effect\": -0.3613, \"times_seen\": 15.0}, {\"site\": 361, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 361, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 361, \"mutant\": \"E\", \"escape\": -0.011880463866509105, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -1.3617, \"times_seen\": 2.0}, {\"site\": 361, \"mutant\": \"G\", \"escape\": 0.08617765781674268, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.1651, \"times_seen\": 4.0}, {\"site\": 361, \"mutant\": \"N\", \"escape\": -0.027115697987769503, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -0.5487, \"times_seen\": 24.0}, {\"site\": 361, \"mutant\": \"S\", \"escape\": -0.009103741584086575, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.0705, \"times_seen\": 3.0}, {\"site\": 361, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"364\", \"functional effect\": -2.4825, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"F\", \"escape\": -0.0870164946206921, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": 0.3737, \"times_seen\": 28.0}, {\"site\": 362, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.6021, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"S\", \"escape\": -0.008881576660433266, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": -2.4808, \"times_seen\": 2.0}, {\"site\": 362, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"365\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"A\", \"escape\": 0.07620319761542592, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -0.4622, \"times_seen\": 7.0}, {\"site\": 363, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -2.9689, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"F\", \"escape\": 0.0046558406113413435, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -1.6583, \"times_seen\": 4.0}, {\"site\": 363, \"mutant\": \"I\", \"escape\": -0.011458697815543064, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -2.019, \"times_seen\": 4.0}, {\"site\": 363, \"mutant\": \"P\", \"escape\": -0.0034476585591653552, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -1.9635, \"times_seen\": 2.0}, {\"site\": 363, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"T\", \"escape\": -0.00031927454035317424, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": 0.0449, \"times_seen\": 1.0}, {\"site\": 363, \"mutant\": \"Y\", \"escape\": -0.00689137454951297, \"epitope\": \"epitope 1\", \"reference_site\": \"366\", \"functional effect\": -1.8807, \"times_seen\": 2.0}, {\"site\": 364, \"mutant\": \"A\", \"escape\": 0.059087940602863515, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.138, \"times_seen\": 30.0}, {\"site\": 364, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 364, \"mutant\": \"F\", \"escape\": 0.014087112016189545, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.7208, \"times_seen\": 3.0}, {\"site\": 364, \"mutant\": \"I\", \"escape\": 0.5029150505832177, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.2354, \"times_seen\": 19.0}, {\"site\": 364, \"mutant\": \"L\", \"escape\": 0.00349903838127877, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.2734, \"times_seen\": 25.0}, {\"site\": 364, \"mutant\": \"M\", \"escape\": 0.023468972806680196, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": -0.1391, \"times_seen\": 13.0}, {\"site\": 364, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"367\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"F\", \"escape\": -0.013122132029056453, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -0.39, \"times_seen\": 13.0}, {\"site\": 365, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -3.0169, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"I\", \"escape\": 0.34655974041799414, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": 0.0653, \"times_seen\": 99.0}, {\"site\": 365, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"P\", \"escape\": 0.000640336205991005, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -1.7436, \"times_seen\": 2.0}, {\"site\": 365, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"368\", \"functional effect\": -0.29, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -2.996, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"C\", \"escape\": -0.017987429926614056, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -1.9688, \"times_seen\": 31.0}, {\"site\": 366, \"mutant\": \"F\", \"escape\": 0.5968782187740814, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -0.9627, \"times_seen\": 59.0}, {\"site\": 366, \"mutant\": \"H\", \"escape\": 0.040497776818865454, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": 0.1515, \"times_seen\": 192.0}, {\"site\": 366, \"mutant\": \"N\", \"escape\": 0.00014511252065627596, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -0.013, \"times_seen\": 2.0}, {\"site\": 366, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": -0.7909, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"369\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 367, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 367, \"mutant\": \"D\", \"escape\": -0.11135930975607912, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.0556, \"times_seen\": 59.0}, {\"site\": 367, \"mutant\": \"H\", \"escape\": -0.03334741085189589, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.1043, \"times_seen\": 52.0}, {\"site\": 367, \"mutant\": \"K\", \"escape\": -0.04499067503563126, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.0551, \"times_seen\": 28.0}, {\"site\": 367, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 367, \"mutant\": \"S\", \"escape\": 0.038747287254894874, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": -0.1012, \"times_seen\": 119.0}, {\"site\": 367, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"370\", \"functional effect\": -2.7039, \"times_seen\": null}, {\"site\": 368, \"mutant\": \"*\", \"escape\": -0.026165362690159098, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -2.6155, \"times_seen\": 10.0}, {\"site\": 368, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -3.1689, \"times_seen\": null}, {\"site\": 368, \"mutant\": \"A\", \"escape\": -0.10029131436122507, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.4914, \"times_seen\": 69.0}, {\"site\": 368, \"mutant\": \"C\", \"escape\": -0.018393876061515567, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -1.1983, \"times_seen\": 29.0}, {\"site\": 368, \"mutant\": \"D\", \"escape\": 0.040993807015723235, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.3662, \"times_seen\": 26.0}, {\"site\": 368, \"mutant\": \"E\", \"escape\": 0.08819970005900118, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.5704, \"times_seen\": 46.0}, {\"site\": 368, \"mutant\": \"F\", \"escape\": 0.3672712283299405, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.3186, \"times_seen\": 59.0}, {\"site\": 368, \"mutant\": \"G\", \"escape\": 0.41399542805549844, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.4595, \"times_seen\": 68.0}, {\"site\": 368, \"mutant\": \"H\", \"escape\": -0.043075291533533275, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.1037, \"times_seen\": 49.0}, {\"site\": 368, \"mutant\": \"I\", \"escape\": -0.048143817288023194, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.0442, \"times_seen\": 29.0}, {\"site\": 368, \"mutant\": \"K\", \"escape\": 0.7525188735964663, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.6695, \"times_seen\": 55.0}, {\"site\": 368, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 368, \"mutant\": \"M\", \"escape\": 0.18974855936876195, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.0595, \"times_seen\": 69.0}, {\"site\": 368, \"mutant\": \"N\", \"escape\": 0.4829323407902413, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.284, \"times_seen\": 25.0}, {\"site\": 368, \"mutant\": \"P\", \"escape\": -0.10507655329392121, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -1.429, \"times_seen\": 156.0}, {\"site\": 368, \"mutant\": \"Q\", \"escape\": -0.03358153699492216, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.2541, \"times_seen\": 84.0}, {\"site\": 368, \"mutant\": \"R\", \"escape\": 0.22617637136171692, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.63, \"times_seen\": 155.0}, {\"site\": 368, \"mutant\": \"S\", \"escape\": 0.8959609078568828, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.2365, \"times_seen\": 113.0}, {\"site\": 368, \"mutant\": \"T\", \"escape\": -0.14894636237867165, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.5176, \"times_seen\": 84.0}, {\"site\": 368, \"mutant\": \"V\", \"escape\": 0.0850281124291693, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": -0.1334, \"times_seen\": 87.0}, {\"site\": 368, \"mutant\": \"W\", \"escape\": 0.014524021587879476, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.4396, \"times_seen\": 66.0}, {\"site\": 368, \"mutant\": \"Y\", \"escape\": -0.0339455064379171, \"epitope\": \"epitope 1\", \"reference_site\": \"371\", \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 369, \"mutant\": \"-\", \"escape\": -9.24763628548671e-06, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.1683, \"times_seen\": 1.0}, {\"site\": 369, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 369, \"mutant\": \"D\", \"escape\": -0.000530872058248206, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.1472, \"times_seen\": 2.0}, {\"site\": 369, \"mutant\": \"P\", \"escape\": 0.03823597357990261, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.4262, \"times_seen\": 29.0}, {\"site\": 369, \"mutant\": \"S\", \"escape\": 0.004464179752907223, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 369, \"mutant\": \"T\", \"escape\": -0.1796829127578979, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.3405, \"times_seen\": 66.0}, {\"site\": 369, \"mutant\": \"V\", \"escape\": -0.03702567942814873, \"epitope\": \"epitope 1\", \"reference_site\": \"372\", \"functional effect\": -0.0329, \"times_seen\": 37.0}, {\"site\": 370, \"mutant\": \"*\", \"escape\": -0.015614247375797457, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -2.9613, \"times_seen\": 2.0}, {\"site\": 370, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.21, \"times_seen\": null}, {\"site\": 370, \"mutant\": \"A\", \"escape\": -0.012464189932355598, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.2148, \"times_seen\": 49.0}, {\"site\": 370, \"mutant\": \"C\", \"escape\": -0.010078637945294004, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.8573, \"times_seen\": 4.0}, {\"site\": 370, \"mutant\": \"D\", \"escape\": 0.6665110673805501, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": 0.0955, \"times_seen\": 16.0}, {\"site\": 370, \"mutant\": \"E\", \"escape\": 0.0010543228492852807, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": 0.0605, \"times_seen\": 20.0}, {\"site\": 370, \"mutant\": \"F\", \"escape\": -0.4080494496392383, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.1184, \"times_seen\": 17.0}, {\"site\": 370, \"mutant\": \"G\", \"escape\": 0.30815611787711605, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1726, \"times_seen\": 42.0}, {\"site\": 370, \"mutant\": \"H\", \"escape\": -2.318707689708949, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1823, \"times_seen\": 43.0}, {\"site\": 370, \"mutant\": \"I\", \"escape\": 0.0004577636142538526, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.1776, \"times_seen\": 12.0}, {\"site\": 370, \"mutant\": \"K\", \"escape\": -0.10171251666718574, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.9567, \"times_seen\": 22.0}, {\"site\": 370, \"mutant\": \"L\", \"escape\": -0.22925345550500698, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.0822, \"times_seen\": 61.0}, {\"site\": 370, \"mutant\": \"M\", \"escape\": -0.0027823447994328654, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.4088, \"times_seen\": 13.0}, {\"site\": 370, \"mutant\": \"N\", \"escape\": -0.5146291247389797, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 370, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 370, \"mutant\": \"Q\", \"escape\": 0.01469111859833127, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1828, \"times_seen\": 29.0}, {\"site\": 370, \"mutant\": \"R\", \"escape\": 0.5475177175939202, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.9029, \"times_seen\": 68.0}, {\"site\": 370, \"mutant\": \"S\", \"escape\": -0.012578325436455573, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.0398, \"times_seen\": 92.0}, {\"site\": 370, \"mutant\": \"T\", \"escape\": -0.16547753261852985, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.1946, \"times_seen\": 67.0}, {\"site\": 370, \"mutant\": \"V\", \"escape\": -0.03149574726976017, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.8733, \"times_seen\": 24.0}, {\"site\": 370, \"mutant\": \"W\", \"escape\": 0.0006711634627531521, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -1.2685, \"times_seen\": 16.0}, {\"site\": 370, \"mutant\": \"Y\", \"escape\": 0.0141585030151756, \"epitope\": \"epitope 1\", \"reference_site\": \"373\", \"functional effect\": -0.5623, \"times_seen\": 18.0}, {\"site\": 371, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": 0.1515, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -2.4492, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"I\", \"escape\": 0.02825762569897499, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.1664, \"times_seen\": 3.0}, {\"site\": 371, \"mutant\": \"L\", \"escape\": 0.8812333430602042, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.0949, \"times_seen\": 59.0}, {\"site\": 371, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -1.203, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"S\", \"escape\": 0.05539997629410205, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.1855, \"times_seen\": 17.0}, {\"site\": 371, \"mutant\": \"V\", \"escape\": -0.01967723412315753, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 371, \"mutant\": \"Y\", \"escape\": 0.019252548774485484, \"epitope\": \"epitope 1\", \"reference_site\": \"374\", \"functional effect\": 0.397, \"times_seen\": 4.0}, {\"site\": 372, \"mutant\": \"*\", \"escape\": -0.02233726579967717, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -2.2564, \"times_seen\": 7.0}, {\"site\": 372, \"mutant\": \"A\", \"escape\": 0.31725114622416434, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.1646, \"times_seen\": 82.0}, {\"site\": 372, \"mutant\": \"C\", \"escape\": -0.34637535013867593, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.0937, \"times_seen\": 58.0}, {\"site\": 372, \"mutant\": \"D\", \"escape\": 0.09027823558132882, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 48.0}, {\"site\": 372, \"mutant\": \"E\", \"escape\": 0.7318510013957025, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 372, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 372, \"mutant\": \"G\", \"escape\": 0.19992668611429412, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.1997, \"times_seen\": 42.0}, {\"site\": 372, \"mutant\": \"H\", \"escape\": 0.19621900012704724, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.3194, \"times_seen\": 35.0}, {\"site\": 372, \"mutant\": \"I\", \"escape\": -0.1460195919060948, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.0579, \"times_seen\": 84.0}, {\"site\": 372, \"mutant\": \"K\", \"escape\": -0.015358308908144705, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.7091, \"times_seen\": 25.0}, {\"site\": 372, \"mutant\": \"L\", \"escape\": -0.0552750814324692, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.2194, \"times_seen\": 153.0}, {\"site\": 372, \"mutant\": \"M\", \"escape\": -0.01966451298490287, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.2135, \"times_seen\": 29.0}, {\"site\": 372, \"mutant\": \"N\", \"escape\": 0.03949583485597964, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.3347, \"times_seen\": 46.0}, {\"site\": 372, \"mutant\": \"P\", \"escape\": -0.7762141395920682, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.3061, \"times_seen\": 81.0}, {\"site\": 372, \"mutant\": \"Q\", \"escape\": 0.0028536000064436438, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.397, \"times_seen\": 23.0}, {\"site\": 372, \"mutant\": \"R\", \"escape\": 0.19835994676025373, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -1.2678, \"times_seen\": 47.0}, {\"site\": 372, \"mutant\": \"S\", \"escape\": -0.36752661194835107, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 227.0}, {\"site\": 372, \"mutant\": \"T\", \"escape\": 0.21860975830294024, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": 0.4444, \"times_seen\": 106.0}, {\"site\": 372, \"mutant\": \"V\", \"escape\": 0.3031091621467707, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.0682, \"times_seen\": 71.0}, {\"site\": 372, \"mutant\": \"W\", \"escape\": -0.10866857827742545, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.1565, \"times_seen\": 26.0}, {\"site\": 372, \"mutant\": \"Y\", \"escape\": -0.3717053786969422, \"epitope\": \"epitope 1\", \"reference_site\": \"375\", \"functional effect\": -0.3609, \"times_seen\": 99.0}, {\"site\": 373, \"mutant\": \"*\", \"escape\": -0.0043222927188430425, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -3.1261, \"times_seen\": 1.0}, {\"site\": 373, \"mutant\": \"A\", \"escape\": 0.01155458411769209, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.6319, \"times_seen\": 46.0}, {\"site\": 373, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -2.9734, \"times_seen\": null}, {\"site\": 373, \"mutant\": \"D\", \"escape\": -0.017384118586197365, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0101, \"times_seen\": 15.0}, {\"site\": 373, \"mutant\": \"E\", \"escape\": -0.0038984359713449012, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.1841, \"times_seen\": 3.0}, {\"site\": 373, \"mutant\": \"F\", \"escape\": -0.038994986860675186, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.9247, \"times_seen\": 10.0}, {\"site\": 373, \"mutant\": \"G\", \"escape\": 0.053966823639670744, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.9607, \"times_seen\": 12.0}, {\"site\": 373, \"mutant\": \"H\", \"escape\": 0.018747579685341274, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.2849, \"times_seen\": 20.0}, {\"site\": 373, \"mutant\": \"I\", \"escape\": -0.026023307387486032, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0169, \"times_seen\": 114.0}, {\"site\": 373, \"mutant\": \"K\", \"escape\": 0.027374661440377476, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.7514, \"times_seen\": 6.0}, {\"site\": 373, \"mutant\": \"L\", \"escape\": 0.02000639428901946, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0194, \"times_seen\": 23.0}, {\"site\": 373, \"mutant\": \"M\", \"escape\": -0.0070778112279185675, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1995, \"times_seen\": 10.0}, {\"site\": 373, \"mutant\": \"N\", \"escape\": -1.7857925182684764, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.3342, \"times_seen\": 111.0}, {\"site\": 373, \"mutant\": \"P\", \"escape\": 0.01893109945334347, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -1.7207, \"times_seen\": 14.0}, {\"site\": 373, \"mutant\": \"Q\", \"escape\": 0.02009900999590638, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.3897, \"times_seen\": 6.0}, {\"site\": 373, \"mutant\": \"R\", \"escape\": -0.3559108322254991, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1864, \"times_seen\": 24.0}, {\"site\": 373, \"mutant\": \"S\", \"escape\": -0.03794590700591642, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1394, \"times_seen\": 128.0}, {\"site\": 373, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 373, \"mutant\": \"V\", \"escape\": -0.7640263223360416, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.1724, \"times_seen\": 27.0}, {\"site\": 373, \"mutant\": \"W\", \"escape\": -0.005892964958943406, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.169, \"times_seen\": 1.0}, {\"site\": 373, \"mutant\": \"Y\", \"escape\": 0.00777885215003526, \"epitope\": \"epitope 1\", \"reference_site\": \"376\", \"functional effect\": -0.0853, \"times_seen\": 16.0}, {\"site\": 374, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 374, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 374, \"mutant\": \"I\", \"escape\": -0.0037140465946044277, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": 0.0743, \"times_seen\": 3.0}, {\"site\": 374, \"mutant\": \"L\", \"escape\": 0.2644672655463698, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -0.2708, \"times_seen\": 24.0}, {\"site\": 374, \"mutant\": \"M\", \"escape\": -0.00945619413406961, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": 0.0102, \"times_seen\": 5.0}, {\"site\": 374, \"mutant\": \"S\", \"escape\": 0.00585927460155623, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -1.298, \"times_seen\": 3.0}, {\"site\": 374, \"mutant\": \"V\", \"escape\": -0.00284521112472633, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -0.9615, \"times_seen\": 3.0}, {\"site\": 374, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"377\", \"functional effect\": -0.67, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"E\", \"escape\": 0.01837094389462075, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.0918, \"times_seen\": 7.0}, {\"site\": 375, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"M\", \"escape\": -0.016439633496479603, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.7998, \"times_seen\": 3.0}, {\"site\": 375, \"mutant\": \"N\", \"escape\": -0.09330277434628653, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.2157, \"times_seen\": 42.0}, {\"site\": 375, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"R\", \"escape\": 0.016376934033470944, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": 0.1052, \"times_seen\": 9.0}, {\"site\": 375, \"mutant\": \"T\", \"escape\": -0.004494817985442622, \"epitope\": \"epitope 1\", \"reference_site\": \"378\", \"functional effect\": -0.2887, \"times_seen\": 1.0}, {\"site\": 376, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.9931, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"F\", \"escape\": -0.004820830856989247, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.9496, \"times_seen\": 1.0}, {\"site\": 376, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.1907, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"R\", \"escape\": -0.003190949639939051, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.2311, \"times_seen\": 1.0}, {\"site\": 376, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -3.2038, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -3.2034, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"Y\", \"escape\": -0.006063513270259008, \"epitope\": \"epitope 1\", \"reference_site\": \"379\", \"functional effect\": -2.8537, \"times_seen\": 3.0}, {\"site\": 377, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -2.7142, \"times_seen\": null}, {\"site\": 377, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 377, \"mutant\": \"C\", \"escape\": -0.05592080774729045, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -2.5867, \"times_seen\": 3.0}, {\"site\": 377, \"mutant\": \"F\", \"escape\": 0.2375623096704055, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -0.1709, \"times_seen\": 15.0}, {\"site\": 377, \"mutant\": \"H\", \"escape\": -0.00316871644447343, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -1.3363, \"times_seen\": 1.0}, {\"site\": 377, \"mutant\": \"L\", \"escape\": 0.01897948479940871, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": -2.6411, \"times_seen\": 1.0}, {\"site\": 377, \"mutant\": \"W\", \"escape\": -0.1586793327876793, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": 0.0603, \"times_seen\": 12.0}, {\"site\": 377, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"380\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 378, \"mutant\": \"*\", \"escape\": -0.0001928074285387004, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -2.5781, \"times_seen\": 1.0}, {\"site\": 378, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 378, \"mutant\": \"E\", \"escape\": 0.005983288860269346, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -1.9055, \"times_seen\": 6.0}, {\"site\": 378, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 378, \"mutant\": \"L\", \"escape\": -0.003501442241615991, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -2.6984, \"times_seen\": 1.0}, {\"site\": 378, \"mutant\": \"R\", \"escape\": 0.0061572243162539494, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -0.2144, \"times_seen\": 34.0}, {\"site\": 378, \"mutant\": \"S\", \"escape\": -0.018716709017338358, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -0.8982, \"times_seen\": 7.0}, {\"site\": 378, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"381\", \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 379, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 379, \"mutant\": \"A\", \"escape\": 0.0007692517784590721, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -0.689, \"times_seen\": 1.0}, {\"site\": 379, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -1.5909, \"times_seen\": null}, {\"site\": 379, \"mutant\": \"L\", \"escape\": 0.06814358145723852, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -0.319, \"times_seen\": 43.0}, {\"site\": 379, \"mutant\": \"M\", \"escape\": 0.030463336548249748, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": -0.8253, \"times_seen\": 10.0}, {\"site\": 379, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"382\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -1.8667, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"F\", \"escape\": -0.007631742203609665, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -2.9952, \"times_seen\": 2.0}, {\"site\": 380, \"mutant\": \"G\", \"escape\": -0.010049275586569827, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -0.9598, \"times_seen\": 14.0}, {\"site\": 380, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -1.7595, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"N\", \"escape\": -0.006728866172504899, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -2.5084, \"times_seen\": 13.0}, {\"site\": 380, \"mutant\": \"R\", \"escape\": -0.06054900469979664, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": -2.2382, \"times_seen\": 1.0}, {\"site\": 380, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"383\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 381, \"mutant\": \"*\", \"escape\": -0.008515085056146761, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -2.9398, \"times_seen\": 1.0}, {\"site\": 381, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 381, \"mutant\": \"A\", \"escape\": -0.03530709755840333, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2093, \"times_seen\": 40.0}, {\"site\": 381, \"mutant\": \"C\", \"escape\": -0.011125220277480663, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -2.4684, \"times_seen\": 6.0}, {\"site\": 381, \"mutant\": \"D\", \"escape\": -0.008255729167477978, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -1.3467, \"times_seen\": 2.0}, {\"site\": 381, \"mutant\": \"E\", \"escape\": -0.00951192032985502, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2733, \"times_seen\": 8.0}, {\"site\": 381, \"mutant\": \"F\", \"escape\": 0.042939581483803606, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": 0.1178, \"times_seen\": 16.0}, {\"site\": 381, \"mutant\": \"G\", \"escape\": -0.06531767254847555, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.8031, \"times_seen\": 25.0}, {\"site\": 381, \"mutant\": \"H\", \"escape\": -0.06724974606115268, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.4325, \"times_seen\": 23.0}, {\"site\": 381, \"mutant\": \"I\", \"escape\": 0.6852730200565476, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.1563, \"times_seen\": 11.0}, {\"site\": 381, \"mutant\": \"K\", \"escape\": 0.01191175671540377, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -1.0839, \"times_seen\": 7.0}, {\"site\": 381, \"mutant\": \"L\", \"escape\": 0.20921785819733643, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.3583, \"times_seen\": 88.0}, {\"site\": 381, \"mutant\": \"M\", \"escape\": -0.022172923313058996, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.248, \"times_seen\": 11.0}, {\"site\": 381, \"mutant\": \"N\", \"escape\": 0.01633717201559183, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.6528, \"times_seen\": 14.0}, {\"site\": 381, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 381, \"mutant\": \"Q\", \"escape\": -0.6560359628383208, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2759, \"times_seen\": 36.0}, {\"site\": 381, \"mutant\": \"R\", \"escape\": 0.15975651873683464, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.4712, \"times_seen\": 42.0}, {\"site\": 381, \"mutant\": \"S\", \"escape\": -0.8919934487614645, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.3294, \"times_seen\": 58.0}, {\"site\": 381, \"mutant\": \"T\", \"escape\": -0.0373750587793374, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.6163, \"times_seen\": 48.0}, {\"site\": 381, \"mutant\": \"V\", \"escape\": 0.04444946463632004, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.2727, \"times_seen\": 19.0}, {\"site\": 381, \"mutant\": \"W\", \"escape\": 0.011915797745369982, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.1322, \"times_seen\": 9.0}, {\"site\": 381, \"mutant\": \"Y\", \"escape\": -0.019041414164017733, \"epitope\": \"epitope 1\", \"reference_site\": \"384\", \"functional effect\": -0.1029, \"times_seen\": 7.0}, {\"site\": 382, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 382, \"mutant\": \"A\", \"escape\": 0.01145887950746924, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -0.0781, \"times_seen\": 5.0}, {\"site\": 382, \"mutant\": \"I\", \"escape\": -0.15090555821363064, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -0.506, \"times_seen\": 41.0}, {\"site\": 382, \"mutant\": \"M\", \"escape\": 0.0034706085426937177, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": -0.3039, \"times_seen\": 15.0}, {\"site\": 382, \"mutant\": \"N\", \"escape\": -0.00515321180378162, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": 0.2744, \"times_seen\": 49.0}, {\"site\": 382, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 382, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"385\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 383, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 383, \"mutant\": \"E\", \"escape\": -0.04215518304074793, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -2.2037, \"times_seen\": 2.0}, {\"site\": 383, \"mutant\": \"I\", \"escape\": 0.004650276280248109, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -1.8361, \"times_seen\": 3.0}, {\"site\": 383, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 383, \"mutant\": \"L\", \"escape\": -0.003756901913755338, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -2.1947, \"times_seen\": 1.0}, {\"site\": 383, \"mutant\": \"R\", \"escape\": 0.0261476792701297, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -0.5299, \"times_seen\": 10.0}, {\"site\": 383, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"386\", \"functional effect\": -0.8204, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"M\", \"escape\": -0.00798542807216963, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -0.9898, \"times_seen\": 4.0}, {\"site\": 384, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -2.9459, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -3.2651, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -3.036, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"387\", \"functional effect\": -2.9934, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"A\", \"escape\": 0.011380037504702463, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.4402, \"times_seen\": 5.0}, {\"site\": 385, \"mutant\": \"D\", \"escape\": 0.018016544967808325, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.6615, \"times_seen\": 11.0}, {\"site\": 385, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -1.1864, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"K\", \"escape\": -0.006759180049440136, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.2214, \"times_seen\": 2.0}, {\"site\": 385, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"S\", \"escape\": -0.10919520824293776, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": -0.3296, \"times_seen\": 12.0}, {\"site\": 385, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"388\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"A\", \"escape\": -0.028043776355485616, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.0555, \"times_seen\": 13.0}, {\"site\": 386, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"E\", \"escape\": 0.4107025134601128, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -0.0239, \"times_seen\": 12.0}, {\"site\": 386, \"mutant\": \"G\", \"escape\": 0.12840412375307772, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -0.6202, \"times_seen\": 31.0}, {\"site\": 386, \"mutant\": \"H\", \"escape\": 0.0018108256058483793, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.1265, \"times_seen\": 2.0}, {\"site\": 386, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -2.689, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"N\", \"escape\": -0.016905705373282502, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -0.9047, \"times_seen\": 16.0}, {\"site\": 386, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"389\", \"functional effect\": -1.8675, \"times_seen\": null}, {\"site\": 387, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 387, \"mutant\": \"F\", \"escape\": -0.05641608294037764, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.0617, \"times_seen\": 5.0}, {\"site\": 387, \"mutant\": \"I\", \"escape\": -0.016700744217442567, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -0.5978, \"times_seen\": 4.0}, {\"site\": 387, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 387, \"mutant\": \"M\", \"escape\": -0.023065952501572316, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.0642, \"times_seen\": 18.0}, {\"site\": 387, \"mutant\": \"P\", \"escape\": 0.01555486277760608, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -2.8832, \"times_seen\": 4.0}, {\"site\": 387, \"mutant\": \"Q\", \"escape\": 0.012634028413866863, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -0.4952, \"times_seen\": 4.0}, {\"site\": 387, \"mutant\": \"R\", \"escape\": -0.0020196606529494445, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -1.5243, \"times_seen\": 1.0}, {\"site\": 387, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"390\", \"functional effect\": -3.2571, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -2.9487, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"F\", \"escape\": 0.019317765611691146, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -1.3162, \"times_seen\": 1.0}, {\"site\": 388, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -3.0135, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"M\", \"escape\": -0.0030353398407657745, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -2.9312, \"times_seen\": 1.0}, {\"site\": 388, \"mutant\": \"R\", \"escape\": -0.0030824102359270265, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -3.0312, \"times_seen\": 1.0}, {\"site\": 388, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"391\", \"functional effect\": -3.0351, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"C\", \"escape\": -0.004198438144527831, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.5699, \"times_seen\": 1.0}, {\"site\": 389, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"L\", \"escape\": -0.006880706714287785, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.2761, \"times_seen\": 10.0}, {\"site\": 389, \"mutant\": \"S\", \"escape\": -0.058158753447516, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -0.9432, \"times_seen\": 4.0}, {\"site\": 389, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -1.8995, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"Y\", \"escape\": -0.0017449022879689033, \"epitope\": \"epitope 1\", \"reference_site\": \"392\", \"functional effect\": -0.1345, \"times_seen\": 1.0}, {\"site\": 390, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 390, \"mutant\": \"A\", \"escape\": 0.008234512919205173, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -0.8816, \"times_seen\": 1.0}, {\"site\": 390, \"mutant\": \"I\", \"escape\": -0.008828125680188514, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -2.7257, \"times_seen\": 5.0}, {\"site\": 390, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -2.9133, \"times_seen\": null}, {\"site\": 390, \"mutant\": \"N\", \"escape\": -0.005026410467144585, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": -0.5996, \"times_seen\": 2.0}, {\"site\": 390, \"mutant\": \"S\", \"escape\": -0.022103834863913152, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 390, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"393\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 391, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 391, \"mutant\": \"D\", \"escape\": 0.5839215859327712, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.0117, \"times_seen\": 6.0}, {\"site\": 391, \"mutant\": \"H\", \"escape\": 0.01791381241934513, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -2.4143, \"times_seen\": 1.0}, {\"site\": 391, \"mutant\": \"I\", \"escape\": -0.0013278153717941174, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -1.4106, \"times_seen\": 6.0}, {\"site\": 391, \"mutant\": \"K\", \"escape\": 0.011342391477736342, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.9108, \"times_seen\": 3.0}, {\"site\": 391, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 391, \"mutant\": \"Q\", \"escape\": 0.03495403938093083, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.2401, \"times_seen\": 2.0}, {\"site\": 391, \"mutant\": \"S\", \"escape\": -0.009407696913791395, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.1483, \"times_seen\": 14.0}, {\"site\": 391, \"mutant\": \"T\", \"escape\": -0.00946530341580351, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -0.0429, \"times_seen\": 7.0}, {\"site\": 391, \"mutant\": \"Y\", \"escape\": -0.018763563273959942, \"epitope\": \"epitope 1\", \"reference_site\": \"394\", \"functional effect\": -1.3135, \"times_seen\": 9.0}, {\"site\": 392, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 392, \"mutant\": \"A\", \"escape\": -0.02464081902135571, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -1.6521, \"times_seen\": 4.0}, {\"site\": 392, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 392, \"mutant\": \"F\", \"escape\": -0.026777418568453046, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -0.5212, \"times_seen\": 9.0}, {\"site\": 392, \"mutant\": \"I\", \"escape\": -0.04185942904304487, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": -0.7646, \"times_seen\": 22.0}, {\"site\": 392, \"mutant\": \"L\", \"escape\": -0.013797044741652517, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": 0.0892, \"times_seen\": 6.0}, {\"site\": 392, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"395\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -2.9509, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.0178, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"D\", \"escape\": -0.003956451874898107, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -1.234, \"times_seen\": 1.0}, {\"site\": 393, \"mutant\": \"F\", \"escape\": -0.009598790122031249, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.0749, \"times_seen\": 6.0}, {\"site\": 393, \"mutant\": \"H\", \"escape\": -0.0730145695748615, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.7207, \"times_seen\": 20.0}, {\"site\": 393, \"mutant\": \"N\", \"escape\": -0.005071328827537, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": -0.1288, \"times_seen\": 1.0}, {\"site\": 393, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"396\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"D\", \"escape\": 0.01821312039903402, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -3.0099, \"times_seen\": 1.0}, {\"site\": 394, \"mutant\": \"L\", \"escape\": 0.010497904509668735, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -0.6754, \"times_seen\": 4.0}, {\"site\": 394, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"S\", \"escape\": -0.0005764213799207394, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -1.9101, \"times_seen\": 1.0}, {\"site\": 394, \"mutant\": \"T\", \"escape\": 0.026132871654507582, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -2.2252, \"times_seen\": 13.0}, {\"site\": 394, \"mutant\": \"V\", \"escape\": -0.011755803649586226, \"epitope\": \"epitope 1\", \"reference_site\": \"397\", \"functional effect\": -0.6478, \"times_seen\": 26.0}, {\"site\": 395, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 395, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 395, \"mutant\": \"E\", \"escape\": -0.002976869987112609, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -2.5021, \"times_seen\": 1.0}, {\"site\": 395, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -2.8109, \"times_seen\": null}, {\"site\": 395, \"mutant\": \"N\", \"escape\": -0.005315632837268092, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -2.7401, \"times_seen\": 1.0}, {\"site\": 395, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"398\", \"functional effect\": -3.2346, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"F\", \"escape\": 0.006383031755370407, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -2.0107, \"times_seen\": 1.0}, {\"site\": 396, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -2.4874, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -3.131, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"399\", \"functional effect\": -3.0019, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"A\", \"escape\": -0.006015805212927279, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.4528, \"times_seen\": 2.0}, {\"site\": 397, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.7856, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -1.7314, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"L\", \"escape\": -0.004040205473380027, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -3.222, \"times_seen\": 1.0}, {\"site\": 397, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -1.5979, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.223, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"Y\", \"escape\": -0.0002047268552872527, \"epitope\": \"epitope 1\", \"reference_site\": \"400\", \"functional effect\": -2.9552, \"times_seen\": 1.0}, {\"site\": 398, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": 1.4893, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": 0.0417, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"I\", \"escape\": -0.0724302309061224, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -1.2893, \"times_seen\": 18.0}, {\"site\": 398, \"mutant\": \"L\", \"escape\": 0.008844711448037232, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -2.3023, \"times_seen\": 8.0}, {\"site\": 398, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": -2.2593, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"401\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"L\", \"escape\": -0.005831017495579627, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -1.6759, \"times_seen\": 2.0}, {\"site\": 399, \"mutant\": \"M\", \"escape\": -0.009145040703539756, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -1.1369, \"times_seen\": 4.0}, {\"site\": 399, \"mutant\": \"N\", \"escape\": -0.0031380995329862377, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -2.3826, \"times_seen\": 1.0}, {\"site\": 399, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -3.0507, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"V\", \"escape\": 0.02876603151478375, \"epitope\": \"epitope 1\", \"reference_site\": \"402\", \"functional effect\": -0.0074, \"times_seen\": 23.0}, {\"site\": 400, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 400, \"mutant\": \"G\", \"escape\": -0.052857286711573984, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -1.8128, \"times_seen\": 5.0}, {\"site\": 400, \"mutant\": \"I\", \"escape\": -0.009017358158469142, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -2.0965, \"times_seen\": 4.0}, {\"site\": 400, \"mutant\": \"K\", \"escape\": 0.10175374987522576, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.2878, \"times_seen\": 59.0}, {\"site\": 400, \"mutant\": \"M\", \"escape\": -0.060643970820363685, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.374, \"times_seen\": 23.0}, {\"site\": 400, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 400, \"mutant\": \"S\", \"escape\": -0.02916247972744745, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -0.4068, \"times_seen\": 7.0}, {\"site\": 400, \"mutant\": \"T\", \"escape\": 0.017523823976545592, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -1.9766, \"times_seen\": 1.0}, {\"site\": 400, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"403\", \"functional effect\": -2.3165, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"A\", \"escape\": 1.0716120210708473, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -0.7782, \"times_seen\": 3.0}, {\"site\": 401, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"E\", \"escape\": 0.02141728392712462, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -1.0488, \"times_seen\": 9.0}, {\"site\": 401, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -2.8796, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"R\", \"escape\": 0.048360540161975704, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -1.5486, \"times_seen\": 18.0}, {\"site\": 401, \"mutant\": \"S\", \"escape\": 0.03902993940510177, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 401, \"mutant\": \"V\", \"escape\": 0.006006790679949987, \"epitope\": \"epitope 1\", \"reference_site\": \"404\", \"functional effect\": -2.6442, \"times_seen\": 1.0}, {\"site\": 402, \"mutant\": \"*\", \"escape\": -0.005031794297207816, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -2.8205, \"times_seen\": 2.0}, {\"site\": 402, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 402, \"mutant\": \"A\", \"escape\": 0.013317551910704526, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": 0.1155, \"times_seen\": 32.0}, {\"site\": 402, \"mutant\": \"C\", \"escape\": -0.01368508603367938, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.5414, \"times_seen\": 5.0}, {\"site\": 402, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 402, \"mutant\": \"E\", \"escape\": -0.02323404309397212, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.2703, \"times_seen\": 27.0}, {\"site\": 402, \"mutant\": \"F\", \"escape\": 0.0015927831983325788, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.0143, \"times_seen\": 6.0}, {\"site\": 402, \"mutant\": \"G\", \"escape\": -0.2782038619426714, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.4299, \"times_seen\": 42.0}, {\"site\": 402, \"mutant\": \"H\", \"escape\": -0.0035058611073652004, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.444, \"times_seen\": 19.0}, {\"site\": 402, \"mutant\": \"I\", \"escape\": -0.008514239262816517, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.8464, \"times_seen\": 12.0}, {\"site\": 402, \"mutant\": \"K\", \"escape\": 0.015520510308999461, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.2485, \"times_seen\": 8.0}, {\"site\": 402, \"mutant\": \"L\", \"escape\": 0.0020507680112307855, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.7652, \"times_seen\": 32.0}, {\"site\": 402, \"mutant\": \"M\", \"escape\": 0.019287308748838564, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.4456, \"times_seen\": 15.0}, {\"site\": 402, \"mutant\": \"N\", \"escape\": -0.03537109805741324, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.177, \"times_seen\": 24.0}, {\"site\": 402, \"mutant\": \"P\", \"escape\": -0.01022263782334033, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -2.2208, \"times_seen\": 5.0}, {\"site\": 402, \"mutant\": \"Q\", \"escape\": 0.021312293876315048, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.7947, \"times_seen\": 9.0}, {\"site\": 402, \"mutant\": \"R\", \"escape\": -0.09198286748352917, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -1.4681, \"times_seen\": 26.0}, {\"site\": 402, \"mutant\": \"S\", \"escape\": 0.07011613414402418, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": 0.0325, \"times_seen\": 32.0}, {\"site\": 402, \"mutant\": \"T\", \"escape\": -0.024443238290938703, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.4711, \"times_seen\": 15.0}, {\"site\": 402, \"mutant\": \"V\", \"escape\": 0.054747764838503174, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.6865, \"times_seen\": 18.0}, {\"site\": 402, \"mutant\": \"W\", \"escape\": -0.0033229114962680024, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -2.549, \"times_seen\": 1.0}, {\"site\": 402, \"mutant\": \"Y\", \"escape\": -0.09588259470968698, \"epitope\": \"epitope 1\", \"reference_site\": \"405\", \"functional effect\": -0.8437, \"times_seen\": 34.0}, {\"site\": 403, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.9827, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"A\", \"escape\": 0.00407765699931206, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.3349, \"times_seen\": 1.0}, {\"site\": 403, \"mutant\": \"D\", \"escape\": -0.059192367654757626, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -1.2607, \"times_seen\": 26.0}, {\"site\": 403, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.6011, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"K\", \"escape\": 0.005769056267187733, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -3.0059, \"times_seen\": 4.0}, {\"site\": 403, \"mutant\": \"Q\", \"escape\": 0.6922696722034463, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -0.2443, \"times_seen\": 35.0}, {\"site\": 403, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"406\", \"functional effect\": -2.6288, \"times_seen\": null}, {\"site\": 404, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 404, \"mutant\": \"A\", \"escape\": 0.011919474041555059, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -1.9623, \"times_seen\": 2.0}, {\"site\": 404, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -0.0389, \"times_seen\": null}, {\"site\": 404, \"mutant\": \"I\", \"escape\": -0.08131791908461974, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -0.1177, \"times_seen\": 44.0}, {\"site\": 404, \"mutant\": \"L\", \"escape\": 0.6915051442647324, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": 0.0434, \"times_seen\": 34.0}, {\"site\": 404, \"mutant\": \"M\", \"escape\": -0.004201330015551152, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -1.3395, \"times_seen\": 10.0}, {\"site\": 404, \"mutant\": \"S\", \"escape\": 0.002757918961811304, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 404, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"407\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 405, \"mutant\": \"*\", \"escape\": 0.018342585220563822, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -2.695, \"times_seen\": 4.0}, {\"site\": 405, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 405, \"mutant\": \"A\", \"escape\": -0.024414502557141934, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.3577, \"times_seen\": 23.0}, {\"site\": 405, \"mutant\": \"C\", \"escape\": -0.014154785990267873, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -2.5459, \"times_seen\": 4.0}, {\"site\": 405, \"mutant\": \"D\", \"escape\": -0.020875575915672167, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.8467, \"times_seen\": 7.0}, {\"site\": 405, \"mutant\": \"E\", \"escape\": -0.021274147945212728, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.7397, \"times_seen\": 24.0}, {\"site\": 405, \"mutant\": \"F\", \"escape\": -0.044097765135093975, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.5255, \"times_seen\": 20.0}, {\"site\": 405, \"mutant\": \"G\", \"escape\": 0.9033848310656171, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4055, \"times_seen\": 38.0}, {\"site\": 405, \"mutant\": \"H\", \"escape\": 0.024292837238365894, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2608, \"times_seen\": 19.0}, {\"site\": 405, \"mutant\": \"I\", \"escape\": -0.026924183049909848, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.5483, \"times_seen\": 89.0}, {\"site\": 405, \"mutant\": \"K\", \"escape\": -1.079177445280538, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4969, \"times_seen\": 63.0}, {\"site\": 405, \"mutant\": \"L\", \"escape\": -0.8538697803994441, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.9469, \"times_seen\": 36.0}, {\"site\": 405, \"mutant\": \"M\", \"escape\": 0.006730086613652836, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.6264, \"times_seen\": 11.0}, {\"site\": 405, \"mutant\": \"N\", \"escape\": -0.05259717521090334, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4278, \"times_seen\": 16.0}, {\"site\": 405, \"mutant\": \"P\", \"escape\": -0.02313164202065329, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4112, \"times_seen\": 40.0}, {\"site\": 405, \"mutant\": \"Q\", \"escape\": -0.024876436150280883, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2147, \"times_seen\": 18.0}, {\"site\": 405, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 405, \"mutant\": \"S\", \"escape\": -0.052269606536842, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2414, \"times_seen\": 94.0}, {\"site\": 405, \"mutant\": \"T\", \"escape\": 0.020757711944496795, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.3503, \"times_seen\": 68.0}, {\"site\": 405, \"mutant\": \"V\", \"escape\": 0.0007848714744683801, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.4723, \"times_seen\": 22.0}, {\"site\": 405, \"mutant\": \"W\", \"escape\": -0.04205690318354911, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.2314, \"times_seen\": 8.0}, {\"site\": 405, \"mutant\": \"Y\", \"escape\": -0.01133474963412932, \"epitope\": \"epitope 1\", \"reference_site\": \"408\", \"functional effect\": -0.0626, \"times_seen\": 15.0}, {\"site\": 406, \"mutant\": \"*\", \"escape\": 0.028011059460260092, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9533, \"times_seen\": 1.0}, {\"site\": 406, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 406, \"mutant\": \"E\", \"escape\": 0.001772906393332007, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -1.3489, \"times_seen\": 9.0}, {\"site\": 406, \"mutant\": \"H\", \"escape\": 0.007605068415467771, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9692, \"times_seen\": 2.0}, {\"site\": 406, \"mutant\": \"K\", \"escape\": -0.008429447302992164, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9548, \"times_seen\": 6.0}, {\"site\": 406, \"mutant\": \"L\", \"escape\": -0.003029845849897407, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.8838, \"times_seen\": 3.0}, {\"site\": 406, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 406, \"mutant\": \"R\", \"escape\": 1.604491463612427, \"epitope\": \"epitope 1\", \"reference_site\": \"409\", \"functional effect\": -2.9451, \"times_seen\": 10.0}, {\"site\": 407, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -1.5536, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"S\", \"escape\": -0.0016044139687074882, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -2.8913, \"times_seen\": 1.0}, {\"site\": 407, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -2.8579, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"V\", \"escape\": -0.02162001839040761, \"epitope\": \"epitope 1\", \"reference_site\": \"410\", \"functional effect\": -0.341, \"times_seen\": 39.0}, {\"site\": 408, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"C\", \"escape\": -0.0038588223604013776, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.4914, \"times_seen\": 2.0}, {\"site\": 408, \"mutant\": \"D\", \"escape\": -0.007058297162483021, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -1.9209, \"times_seen\": 2.0}, {\"site\": 408, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -0.7117, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.8117, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"S\", \"escape\": -0.025848681004507254, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -1.204, \"times_seen\": 27.0}, {\"site\": 408, \"mutant\": \"T\", \"escape\": -0.012163190271762553, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 408, \"mutant\": \"V\", \"escape\": -0.0006706277840034158, \"epitope\": \"epitope 1\", \"reference_site\": \"411\", \"functional effect\": -2.5928, \"times_seen\": 18.0}, {\"site\": 409, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"H\", \"escape\": -0.0023886896980709698, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.5839, \"times_seen\": 1.0}, {\"site\": 409, \"mutant\": \"L\", \"escape\": 0.001693040240110186, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.9764, \"times_seen\": 1.0}, {\"site\": 409, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -3.0028, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.8733, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -1.8136, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.8789, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"T\", \"escape\": 0.014375629975827723, \"epitope\": \"epitope 1\", \"reference_site\": \"412\", \"functional effect\": -2.8876, \"times_seen\": 2.0}, {\"site\": 410, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.9652, \"times_seen\": null}, {\"site\": 410, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 410, \"mutant\": \"A\", \"escape\": -0.009674614720914186, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -0.7148, \"times_seen\": 6.0}, {\"site\": 410, \"mutant\": \"E\", \"escape\": -0.004980787820057912, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -1.6159, \"times_seen\": 4.0}, {\"site\": 410, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 410, \"mutant\": \"R\", \"escape\": -0.03228207293245286, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -0.2529, \"times_seen\": 12.0}, {\"site\": 410, \"mutant\": \"S\", \"escape\": -1.228455371760388, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.0003, \"times_seen\": 10.0}, {\"site\": 410, \"mutant\": \"V\", \"escape\": -0.01810322215725392, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.7582, \"times_seen\": 4.0}, {\"site\": 410, \"mutant\": \"W\", \"escape\": -0.009513582939590315, \"epitope\": \"epitope 1\", \"reference_site\": \"413\", \"functional effect\": -2.2885, \"times_seen\": 1.0}, {\"site\": 411, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -1.4209, \"times_seen\": null}, {\"site\": 411, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 411, \"mutant\": \"E\", \"escape\": 1.5234234094829904, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.3983, \"times_seen\": 1.0}, {\"site\": 411, \"mutant\": \"H\", \"escape\": 0.009609694744997146, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -1.8486, \"times_seen\": 12.0}, {\"site\": 411, \"mutant\": \"K\", \"escape\": 0.06981130504001222, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.7464, \"times_seen\": 16.0}, {\"site\": 411, \"mutant\": \"L\", \"escape\": 0.009572268715861388, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -2.1803, \"times_seen\": 7.0}, {\"site\": 411, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 411, \"mutant\": \"R\", \"escape\": -0.004640109946347203, \"epitope\": \"epitope 1\", \"reference_site\": \"414\", \"functional effect\": -0.6686, \"times_seen\": 8.0}, {\"site\": 412, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 412, \"mutant\": \"A\", \"escape\": 0.0965734976490626, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.1443, \"times_seen\": 11.0}, {\"site\": 412, \"mutant\": \"I\", \"escape\": -0.03222956720743265, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.4647, \"times_seen\": 16.0}, {\"site\": 412, \"mutant\": \"K\", \"escape\": 0.0808074683315144, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.1293, \"times_seen\": 4.0}, {\"site\": 412, \"mutant\": \"L\", \"escape\": -0.008728449251659874, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -2.1157, \"times_seen\": 2.0}, {\"site\": 412, \"mutant\": \"N\", \"escape\": -0.1438228880449943, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.3731, \"times_seen\": 48.0}, {\"site\": 412, \"mutant\": \"R\", \"escape\": 0.027750108187322705, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.043, \"times_seen\": 1.0}, {\"site\": 412, \"mutant\": \"S\", \"escape\": 0.7579978439611406, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": -0.2426, \"times_seen\": 18.0}, {\"site\": 412, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"415\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -3.0001, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"D\", \"escape\": 0.003586708421102995, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.4364, \"times_seen\": 5.0}, {\"site\": 413, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.8403, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"N\", \"escape\": 0.013439844052452537, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 413, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -1.6747, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"S\", \"escape\": -0.0016176621326360445, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -3.1206, \"times_seen\": 1.0}, {\"site\": 413, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.3923, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"416\", \"functional effect\": -2.1237, \"times_seen\": null}, {\"site\": 414, \"mutant\": \"*\", \"escape\": -0.02537448658194349, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -2.6092, \"times_seen\": 5.0}, {\"site\": 414, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -2.7518, \"times_seen\": null}, {\"site\": 414, \"mutant\": \"A\", \"escape\": -0.09649507486052085, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.0135, \"times_seen\": 28.0}, {\"site\": 414, \"mutant\": \"C\", \"escape\": -0.029262833563573863, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.9425, \"times_seen\": 12.0}, {\"site\": 414, \"mutant\": \"D\", \"escape\": -0.005288085755458623, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -1.1213, \"times_seen\": 10.0}, {\"site\": 414, \"mutant\": \"E\", \"escape\": -0.00447594304016953, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.8444, \"times_seen\": 13.0}, {\"site\": 414, \"mutant\": \"F\", \"escape\": -0.01451311857552875, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.2752, \"times_seen\": 11.0}, {\"site\": 414, \"mutant\": \"G\", \"escape\": -0.5717942783624574, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.7688, \"times_seen\": 29.0}, {\"site\": 414, \"mutant\": \"H\", \"escape\": -0.5013880780254524, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0806, \"times_seen\": 24.0}, {\"site\": 414, \"mutant\": \"I\", \"escape\": 0.024929559274983328, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.171, \"times_seen\": 21.0}, {\"site\": 414, \"mutant\": \"K\", \"escape\": 0.4302341148377368, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.1677, \"times_seen\": 39.0}, {\"site\": 414, \"mutant\": \"L\", \"escape\": -0.030412067854332172, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0495, \"times_seen\": 45.0}, {\"site\": 414, \"mutant\": \"M\", \"escape\": 0.04764140163245286, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0532, \"times_seen\": 15.0}, {\"site\": 414, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 414, \"mutant\": \"P\", \"escape\": -0.11999624804503853, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.1462, \"times_seen\": 42.0}, {\"site\": 414, \"mutant\": \"Q\", \"escape\": -0.011579717861326083, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.0824, \"times_seen\": 4.0}, {\"site\": 414, \"mutant\": \"R\", \"escape\": 0.06584043488369791, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.1734, \"times_seen\": 54.0}, {\"site\": 414, \"mutant\": \"S\", \"escape\": 0.3467866443854447, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.2119, \"times_seen\": 40.0}, {\"site\": 414, \"mutant\": \"T\", \"escape\": 0.025802356377470935, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.0517, \"times_seen\": 62.0}, {\"site\": 414, \"mutant\": \"V\", \"escape\": -0.04639322641340242, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.2189, \"times_seen\": 23.0}, {\"site\": 414, \"mutant\": \"W\", \"escape\": -0.004888829961339915, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": -0.3319, \"times_seen\": 5.0}, {\"site\": 414, \"mutant\": \"Y\", \"escape\": 0.20758986279875766, \"epitope\": \"epitope 1\", \"reference_site\": \"417\", \"functional effect\": 0.1926, \"times_seen\": 19.0}, {\"site\": 415, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"L\", \"escape\": 0.0015682849554332881, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -1.2658, \"times_seen\": 1.0}, {\"site\": 415, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -1.9397, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -2.8834, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"V\", \"escape\": -0.0555915801223352, \"epitope\": \"epitope 1\", \"reference_site\": \"418\", \"functional effect\": -0.8129, \"times_seen\": 14.0}, {\"site\": 416, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -3.2606, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -3.0208, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -3.054, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"S\", \"escape\": -0.0034961677124371524, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -2.7621, \"times_seen\": 1.0}, {\"site\": 416, \"mutant\": \"T\", \"escape\": -0.009359400875940138, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -2.4187, \"times_seen\": 4.0}, {\"site\": 416, \"mutant\": \"V\", \"escape\": 0.003948024064424976, \"epitope\": \"epitope 1\", \"reference_site\": \"419\", \"functional effect\": -2.8538, \"times_seen\": 4.0}, {\"site\": 417, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 417, \"mutant\": \"E\", \"escape\": -0.01409556922958371, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -1.2512, \"times_seen\": 4.0}, {\"site\": 417, \"mutant\": \"G\", \"escape\": -0.006438751038066754, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -2.7506, \"times_seen\": 5.0}, {\"site\": 417, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -1.248, \"times_seen\": null}, {\"site\": 417, \"mutant\": \"I\", \"escape\": -0.009915902133496043, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -2.9881, \"times_seen\": 1.0}, {\"site\": 417, \"mutant\": \"N\", \"escape\": -0.40057499176878975, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -0.0155, \"times_seen\": 29.0}, {\"site\": 417, \"mutant\": \"R\", \"escape\": 0.009809253176910747, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -2.0778, \"times_seen\": 5.0}, {\"site\": 417, \"mutant\": \"Y\", \"escape\": -0.6093325436960866, \"epitope\": \"epitope 1\", \"reference_site\": \"420\", \"functional effect\": -1.6177, \"times_seen\": 12.0}, {\"site\": 418, \"mutant\": \"*\", \"escape\": -0.004833505884567178, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.9341, \"times_seen\": 1.0}, {\"site\": 418, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 418, \"mutant\": \"A\", \"escape\": 0.023105509613775853, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.0424, \"times_seen\": 4.0}, {\"site\": 418, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -3.0792, \"times_seen\": null}, {\"site\": 418, \"mutant\": \"F\", \"escape\": -0.008145314673232564, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -0.3202, \"times_seen\": 14.0}, {\"site\": 418, \"mutant\": \"H\", \"escape\": -0.011872978960395698, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -0.9485, \"times_seen\": 10.0}, {\"site\": 418, \"mutant\": \"I\", \"escape\": -0.013931943839793853, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -2.8359, \"times_seen\": 6.0}, {\"site\": 418, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": -0.7687, \"times_seen\": null}, {\"site\": 418, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"421\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -1.3291, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -3.1359, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"S\", \"escape\": 0.0012288953839381849, \"epitope\": \"epitope 1\", \"reference_site\": \"422\", \"functional effect\": -0.3505, \"times_seen\": 1.0}, {\"site\": 420, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 420, \"mutant\": \"C\", \"escape\": -0.05746261245539485, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -0.1813, \"times_seen\": 1.0}, {\"site\": 420, \"mutant\": \"H\", \"escape\": -0.29527672779698166, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -2.2681, \"times_seen\": 1.0}, {\"site\": 420, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": -2.8029, \"times_seen\": null}, {\"site\": 420, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"423\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -1.7255, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"G\", \"escape\": -0.03924428081490472, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 421, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"N\", \"escape\": -0.007346566813956895, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -2.5108, \"times_seen\": 2.0}, {\"site\": 421, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -1.4729, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"R\", \"escape\": -0.00983036958345421, \"epitope\": \"epitope 1\", \"reference_site\": \"424\", \"functional effect\": -0.928, \"times_seen\": 10.0}, {\"site\": 422, \"mutant\": \"I\", \"escape\": 0.01375259475974046, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.2721, \"times_seen\": 7.0}, {\"site\": 422, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 422, \"mutant\": \"M\", \"escape\": -0.0038524361560789136, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.7344, \"times_seen\": 2.0}, {\"site\": 422, \"mutant\": \"P\", \"escape\": 0.0013322913526250387, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -1.9279, \"times_seen\": 1.0}, {\"site\": 422, \"mutant\": \"Q\", \"escape\": -0.004210311138267459, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.5957, \"times_seen\": 1.0}, {\"site\": 422, \"mutant\": \"V\", \"escape\": 0.016327633321226803, \"epitope\": \"epitope 1\", \"reference_site\": \"425\", \"functional effect\": -0.6278, \"times_seen\": 7.0}, {\"site\": 423, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -2.878, \"times_seen\": null}, {\"site\": 423, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 423, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 423, \"mutant\": \"S\", \"escape\": 0.005817332414841281, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -1.765, \"times_seen\": 13.0}, {\"site\": 423, \"mutant\": \"T\", \"escape\": -0.006298290091232192, \"epitope\": \"epitope 1\", \"reference_site\": \"426\", \"functional effect\": -2.888, \"times_seen\": 3.0}, {\"site\": 424, \"mutant\": \"A\", \"escape\": 0.017712825892305335, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.6326, \"times_seen\": 7.0}, {\"site\": 424, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 424, \"mutant\": \"E\", \"escape\": -0.04326367417879844, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.1615, \"times_seen\": 9.0}, {\"site\": 424, \"mutant\": \"G\", \"escape\": -2.528225645555873, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.5222, \"times_seen\": 16.0}, {\"site\": 424, \"mutant\": \"H\", \"escape\": -0.011908698798092301, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.4526, \"times_seen\": 12.0}, {\"site\": 424, \"mutant\": \"N\", \"escape\": -0.3614288359684538, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.2103, \"times_seen\": 48.0}, {\"site\": 424, \"mutant\": \"R\", \"escape\": -0.03673338988667044, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -1.0111, \"times_seen\": 4.0}, {\"site\": 424, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.5455, \"times_seen\": null}, {\"site\": 424, \"mutant\": \"V\", \"escape\": -0.00892364898938526, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.4356, \"times_seen\": 2.0}, {\"site\": 424, \"mutant\": \"Y\", \"escape\": 0.13159154961204939, \"epitope\": \"epitope 1\", \"reference_site\": \"427\", \"functional effect\": -0.3463, \"times_seen\": 27.0}, {\"site\": 425, \"mutant\": \"A\", \"escape\": -0.005440791859378047, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.3824, \"times_seen\": 5.0}, {\"site\": 425, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 425, \"mutant\": \"E\", \"escape\": -0.013187385066963838, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.1124, \"times_seen\": 9.0}, {\"site\": 425, \"mutant\": \"G\", \"escape\": -0.013796427088293551, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.96, \"times_seen\": 9.0}, {\"site\": 425, \"mutant\": \"H\", \"escape\": -0.014398845928341673, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.1979, \"times_seen\": 4.0}, {\"site\": 425, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -2.5958, \"times_seen\": null}, {\"site\": 425, \"mutant\": \"V\", \"escape\": -0.010746850131541396, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.2893, \"times_seen\": 4.0}, {\"site\": 425, \"mutant\": \"Y\", \"escape\": 0.00014852820390445046, \"epitope\": \"epitope 1\", \"reference_site\": \"428\", \"functional effect\": -0.8063, \"times_seen\": 18.0}, {\"site\": 426, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 426, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.3302, \"times_seen\": null}, {\"site\": 426, \"mutant\": \"L\", \"escape\": -0.009723882633559784, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.3704, \"times_seen\": 3.0}, {\"site\": 426, \"mutant\": \"S\", \"escape\": -0.001579022355394351, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.3682, \"times_seen\": 1.0}, {\"site\": 426, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.9588, \"times_seen\": null}, {\"site\": 426, \"mutant\": \"Y\", \"escape\": -0.003697854949754296, \"epitope\": \"epitope 1\", \"reference_site\": \"429\", \"functional effect\": -2.1454, \"times_seen\": 1.0}, {\"site\": 427, \"mutant\": \"A\", \"escape\": 0.015455673989087506, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -1.1343, \"times_seen\": 6.0}, {\"site\": 427, \"mutant\": \"I\", \"escape\": -0.0512839912136098, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -0.092, \"times_seen\": 30.0}, {\"site\": 427, \"mutant\": \"K\", \"escape\": 0.013208469056963323, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -1.7059, \"times_seen\": 1.0}, {\"site\": 427, \"mutant\": \"S\", \"escape\": -0.0008873127154427979, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": -0.7532, \"times_seen\": 5.0}, {\"site\": 427, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"430\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -3.1899, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"D\", \"escape\": -0.014775503638881745, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -1.2965, \"times_seen\": 7.0}, {\"site\": 428, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -2.9501, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"S\", \"escape\": -0.003778373230791531, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -2.9554, \"times_seen\": 1.0}, {\"site\": 428, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"431\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -3.0255, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -0.53, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -2.5367, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"Y\", \"escape\": 0.005611074251481908, \"epitope\": \"epitope 1\", \"reference_site\": \"432\", \"functional effect\": -2.7205, \"times_seen\": 3.0}, {\"site\": 430, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -2.6833, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -3.0191, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -0.8518, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"I\", \"escape\": -0.007689751712924937, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -1.3058, \"times_seen\": 4.0}, {\"site\": 430, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -2.9112, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"M\", \"escape\": -0.0005161854809446402, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": -2.811, \"times_seen\": 2.0}, {\"site\": 430, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"433\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 431, \"mutant\": \"F\", \"escape\": -0.014985452910296621, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.0207, \"times_seen\": 1.0}, {\"site\": 431, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 431, \"mutant\": \"L\", \"escape\": -0.0011049000113833014, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -1.4261, \"times_seen\": 2.0}, {\"site\": 431, \"mutant\": \"M\", \"escape\": -0.012009557422983139, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.5007, \"times_seen\": 7.0}, {\"site\": 431, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.9182, \"times_seen\": null}, {\"site\": 431, \"mutant\": \"V\", \"escape\": -0.9549896280421899, \"epitope\": \"epitope 1\", \"reference_site\": \"434\", \"functional effect\": -0.4859, \"times_seen\": 15.0}, {\"site\": 432, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 432, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -3.0514, \"times_seen\": null}, {\"site\": 432, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 432, \"mutant\": \"S\", \"escape\": -0.05207794192956369, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -0.0533, \"times_seen\": 24.0}, {\"site\": 432, \"mutant\": \"T\", \"escape\": -0.05060657514847747, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -0.5215, \"times_seen\": 19.0}, {\"site\": 432, \"mutant\": \"V\", \"escape\": 0.013327958877875702, \"epitope\": \"epitope 1\", \"reference_site\": \"435\", \"functional effect\": -1.2557, \"times_seen\": 9.0}, {\"site\": 433, \"mutant\": \"*\", \"escape\": -0.015884567532969053, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -2.5145, \"times_seen\": 10.0}, {\"site\": 433, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -3.1203, \"times_seen\": null}, {\"site\": 433, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -3.0454, \"times_seen\": null}, {\"site\": 433, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -2.542, \"times_seen\": null}, {\"site\": 433, \"mutant\": \"R\", \"escape\": -0.024868863171004875, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": -2.0667, \"times_seen\": 22.0}, {\"site\": 433, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"436\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.9261, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"S\", \"escape\": -0.0036011210968362453, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"-\", \"escape\": 1.5341444868763554, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.4674, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"A\", \"escape\": 0.0491004154741001, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.3883, \"times_seen\": 5.0}, {\"site\": 435, \"mutant\": \"C\", \"escape\": 1.9430764553881392, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.1849, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"G\", \"escape\": -0.013518840882798647, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.9279, \"times_seen\": 2.0}, {\"site\": 435, \"mutant\": \"I\", \"escape\": 0.022887706712292566, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.7564, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"N\", \"escape\": 2.9978861059507937, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.0882, \"times_seen\": 8.0}, {\"site\": 435, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.9463, \"times_seen\": null}, {\"site\": 435, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 435, \"mutant\": \"T\", \"escape\": 0.05000011836968374, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.1017, \"times_seen\": 6.0}, {\"site\": 436, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"A\", \"escape\": 0.016427143526268763, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"D\", \"escape\": -0.02710013345112194, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"F\", \"escape\": 3.832582787896979, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"mutant\": \"G\", \"escape\": -0.006256425652795945, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"H\", \"escape\": 0.03431372346877369, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"I\", \"escape\": -0.007500558674593125, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"K\", \"escape\": 2.6665685717902377, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"mutant\": \"L\", \"escape\": 0.049014875473202844, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"mutant\": \"M\", \"escape\": -0.0008700304490536247, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"Q\", \"escape\": 0.019096661658557862, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"mutant\": \"R\", \"escape\": 0.022321343659805398, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"S\", \"escape\": 3.841301635776083, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"mutant\": \"T\", \"escape\": 4.2685953534301175, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"V\", \"escape\": 0.005009097771370356, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"W\", \"escape\": 0.016481787270732528, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"mutant\": \"Y\", \"escape\": 4.831417215856227, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 437, \"mutant\": \"*\", \"escape\": -0.43239155163434884, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.7496, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 437, \"mutant\": \"A\", \"escape\": -0.01612973387200665, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.028, \"times_seen\": 21.0}, {\"site\": 437, \"mutant\": \"C\", \"escape\": 0.0021528630841421963, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.979, \"times_seen\": 1.0}, {\"site\": 437, \"mutant\": \"D\", \"escape\": 2.072148802120876, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1224, \"times_seen\": 14.0}, {\"site\": 437, \"mutant\": \"E\", \"escape\": -0.027912233257521114, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.3113, \"times_seen\": 15.0}, {\"site\": 437, \"mutant\": \"F\", \"escape\": 2.0717051386142855, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.206, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"G\", \"escape\": -0.025087624400436485, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0017, \"times_seen\": 24.0}, {\"site\": 437, \"mutant\": \"H\", \"escape\": 0.442001192767205, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.221, \"times_seen\": 12.0}, {\"site\": 437, \"mutant\": \"I\", \"escape\": -0.018195677349063313, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8004, \"times_seen\": 13.0}, {\"site\": 437, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 437, \"mutant\": \"L\", \"escape\": 0.06668710845978768, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8499, \"times_seen\": 18.0}, {\"site\": 437, \"mutant\": \"M\", \"escape\": 0.02104416542401308, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.0401, \"times_seen\": 10.0}, {\"site\": 437, \"mutant\": \"N\", \"escape\": -0.04472080009416803, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2118, \"times_seen\": 36.0}, {\"site\": 437, \"mutant\": \"P\", \"escape\": 0.036938368307112154, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.534, \"times_seen\": 8.0}, {\"site\": 437, \"mutant\": \"Q\", \"escape\": 0.010580494466850863, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1906, \"times_seen\": 16.0}, {\"site\": 437, \"mutant\": \"R\", \"escape\": -0.07271886969535121, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.1206, \"times_seen\": 36.0}, {\"site\": 437, \"mutant\": \"S\", \"escape\": 0.03962198683342554, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2856, \"times_seen\": 44.0}, {\"site\": 437, \"mutant\": \"T\", \"escape\": -0.040917580438122575, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0087, \"times_seen\": 29.0}, {\"site\": 437, \"mutant\": \"V\", \"escape\": 1.5370541625533614, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.4789, \"times_seen\": 13.0}, {\"site\": 437, \"mutant\": \"W\", \"escape\": 0.006973859553402811, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.2464, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"Y\", \"escape\": 0.025723488302595042, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.2806, \"times_seen\": 16.0}, {\"site\": 438, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 438, \"mutant\": \"F\", \"escape\": 0.02647816813481393, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.1303, \"times_seen\": 10.0}, {\"site\": 438, \"mutant\": \"I\", \"escape\": -0.0008405549647014136, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0594, \"times_seen\": 19.0}, {\"site\": 438, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 438, \"mutant\": \"M\", \"escape\": -0.0053318954744334115, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0273, \"times_seen\": 3.0}, {\"site\": 438, \"mutant\": \"P\", \"escape\": -0.026724615483474563, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -2.2021, \"times_seen\": 6.0}, {\"site\": 438, \"mutant\": \"Q\", \"escape\": -0.006271509311207683, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.4385, \"times_seen\": 1.0}, {\"site\": 438, \"mutant\": \"R\", \"escape\": -0.009767884753971967, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.74, \"times_seen\": 7.0}, {\"site\": 438, \"mutant\": \"V\", \"escape\": -0.002336955752521854, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.3662, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"E\", \"escape\": 0.037320976751014985, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.6793, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"N\", \"escape\": -0.007310508092986951, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -2.4152, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"V\", \"escape\": 0.017156480692227263, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -0.8693, \"times_seen\": 2.0}, {\"site\": 439, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"A\", \"escape\": -0.0018508962770346098, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"F\", \"escape\": 0.02547891296088903, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"G\", \"escape\": 1.4563559371982857, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"I\", \"escape\": 0.028627963460388005, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"N\", \"escape\": 4.061554094319634, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"mutant\": \"R\", \"escape\": 0.028944033712633876, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"E\", \"escape\": 5.63100423612968, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"I\", \"escape\": 5.105792618876912, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"L\", \"escape\": 3.5897397921326712, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"mutant\": \"M\", \"escape\": 5.446932297015271, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"mutant\": \"N\", \"escape\": 5.1608551404122265, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"R\", \"escape\": 3.319825656559487, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"mutant\": \"T\", \"escape\": 6.123173736421349, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"mutant\": \"A\", \"escape\": 5.902019566322775, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"mutant\": \"E\", \"escape\": 3.9793199775315413, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"mutant\": \"F\", \"escape\": 5.777817042399776, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"mutant\": \"G\", \"escape\": 5.435605704646021, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"I\", \"escape\": 0.06486968350891383, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"mutant\": \"L\", \"escape\": 0.10381107713727365, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"M\", \"escape\": 1.8121877468603933, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 442, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"*\", \"escape\": 0.01704085001058422, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 443, \"mutant\": \"A\", \"escape\": -0.13215564266637744, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"mutant\": \"C\", \"escape\": 0.0030289614883239994, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"mutant\": \"D\", \"escape\": -1.1178473291233153, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"mutant\": \"E\", \"escape\": 3.144212005693318, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"F\", \"escape\": 2.8850751630196485, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"mutant\": \"G\", \"escape\": -0.7636926075869136, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"mutant\": \"H\", \"escape\": 1.4036104483163871, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"mutant\": \"I\", \"escape\": 4.465674215902675, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"mutant\": \"K\", \"escape\": 3.035343859400086, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"L\", \"escape\": 3.3899456114186157, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"mutant\": \"M\", \"escape\": 2.3698456367836256, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"mutant\": \"N\", \"escape\": -0.9090323970409143, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"mutant\": \"P\", \"escape\": 5.917862827319068, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"mutant\": \"Q\", \"escape\": -0.02130403599780089, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"mutant\": \"R\", \"escape\": 3.151992191693694, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"T\", \"escape\": 4.338902376103604, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"mutant\": \"V\", \"escape\": 4.002063487234195, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"mutant\": \"W\", \"escape\": 2.9877229181564315, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"mutant\": \"Y\", \"escape\": 3.7215649679543388, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 444, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"D\", \"escape\": 6.640133123584938, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"R\", \"escape\": 6.9910636155979695, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"mutant\": \"S\", \"escape\": 5.399063074777597, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"mutant\": \"V\", \"escape\": 6.678236397419462, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"D\", \"escape\": 3.3027935937430053, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"K\", \"escape\": 4.941555780752706, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"S\", \"escape\": 3.556761198509068, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"mutant\": \"T\", \"escape\": 3.2982285834944176, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"mutant\": \"Y\", \"escape\": 3.9417863964845368, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 446, \"mutant\": \"*\", \"escape\": 0.008445034238556406, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -2.6941, \"times_seen\": 1.0}, {\"site\": 446, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 446, \"mutant\": \"C\", \"escape\": -0.0307290815327942, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.4238, \"times_seen\": 2.0}, {\"site\": 446, \"mutant\": \"D\", \"escape\": -0.0070845570883118466, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2586, \"times_seen\": 9.0}, {\"site\": 446, \"mutant\": \"F\", \"escape\": -0.01700233426493981, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.1014, \"times_seen\": 12.0}, {\"site\": 446, \"mutant\": \"H\", \"escape\": -0.0976506885387023, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2543, \"times_seen\": 80.0}, {\"site\": 446, \"mutant\": \"N\", \"escape\": 0.04887441661667216, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.3976, \"times_seen\": 23.0}, {\"site\": 446, \"mutant\": \"S\", \"escape\": 0.3181864735443787, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.4215, \"times_seen\": 9.0}, {\"site\": 446, \"mutant\": \"V\", \"escape\": 3.3332591031449126, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.095, \"times_seen\": 5.0}, {\"site\": 446, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"D\", \"escape\": 1.2022407453719384, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"mutant\": \"G\", \"escape\": 0.14906613288498383, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"H\", \"escape\": -0.02331482548619225, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"K\", \"escape\": -1.2395902295705836, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.1636, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"S\", \"escape\": 6.319726305393131, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"mutant\": \"T\", \"escape\": 5.710660039507474, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"mutant\": \"Y\", \"escape\": 0.049310057235704974, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 448, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.5122, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"-\", \"escape\": 0.05810435917243956, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 448, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -0.4405, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"H\", \"escape\": 1.650666746250599, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.0316, \"times_seen\": 30.0}, {\"site\": 448, \"mutant\": \"L\", \"escape\": 0.06352754936609514, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.5391, \"times_seen\": 5.0}, {\"site\": 448, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.1395, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"mutant\": \"*\", \"escape\": -0.0013112829486073168, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"mutant\": \"-\", \"escape\": 0.016457986386659185, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 449, \"mutant\": \"A\", \"escape\": 0.04449928696971482, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"mutant\": \"C\", \"escape\": 0.991289755368235, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"mutant\": \"D\", \"escape\": -0.03152440926541618, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"mutant\": \"E\", \"escape\": -0.018631306830825742, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"F\", \"escape\": 0.904464328802799, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"mutant\": \"G\", \"escape\": -0.07195898031198282, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"mutant\": \"H\", \"escape\": -0.03690237152744968, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"mutant\": \"I\", \"escape\": -0.07831356105501613, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"mutant\": \"K\", \"escape\": -0.014976751894210383, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"mutant\": \"M\", \"escape\": 0.08853385749800997, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"mutant\": \"N\", \"escape\": -0.03781229992920182, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"mutant\": \"P\", \"escape\": 0.10137836137218854, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"mutant\": \"Q\", \"escape\": 0.9148281921785856, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"R\", \"escape\": 0.15644970658104815, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"mutant\": \"S\", \"escape\": 0.6830723697409273, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"mutant\": \"T\", \"escape\": 2.3950307069044503, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"V\", \"escape\": -0.020241535039453876, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"mutant\": \"W\", \"escape\": 0.6432546063871584, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"mutant\": \"Y\", \"escape\": 0.01990202091713323, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.1313, \"times_seen\": 22.0}, {\"site\": 450, \"mutant\": \"*\", \"escape\": 0.003474726326575292, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -2.3815, \"times_seen\": 1.0}, {\"site\": 450, \"mutant\": \"C\", \"escape\": -0.0024000944246925873, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -1.9525, \"times_seen\": 1.0}, {\"site\": 450, \"mutant\": \"F\", \"escape\": 0.16709511621115822, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.4406, \"times_seen\": 13.0}, {\"site\": 450, \"mutant\": \"H\", \"escape\": -0.043041248694975554, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.9062, \"times_seen\": 9.0}, {\"site\": 450, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 450, \"mutant\": \"R\", \"escape\": -0.007123284727517342, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.6085, \"times_seen\": 3.0}, {\"site\": 450, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.1241, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"G\", \"escape\": -0.005916203101142011, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0722, \"times_seen\": 2.0}, {\"site\": 451, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"K\", \"escape\": -0.0054773434802644965, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0305, \"times_seen\": 3.0}, {\"site\": 451, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.2549, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"F\", \"escape\": -0.009487311678158616, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -0.0855, \"times_seen\": 21.0}, {\"site\": 452, \"mutant\": \"I\", \"escape\": -0.008474907995267225, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.2134, \"times_seen\": 3.0}, {\"site\": 452, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"M\", \"escape\": -0.06056040482334041, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.1937, \"times_seen\": 17.0}, {\"site\": 452, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -0.6037, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"Q\", \"escape\": -0.011341731375148377, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": 0.2447, \"times_seen\": 4.0}, {\"site\": 452, \"mutant\": \"S\", \"escape\": -0.00791477544047634, \"epitope\": \"epitope 1\", \"reference_site\": \"455\", \"functional effect\": -0.0584, \"times_seen\": 5.0}, {\"site\": 453, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -3.2691, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"I\", \"escape\": -0.00895839318756302, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -0.306, \"times_seen\": 1.0}, {\"site\": 453, \"mutant\": \"L\", \"escape\": -0.03488161922090873, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -0.6037, \"times_seen\": 11.0}, {\"site\": 453, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -2.5998, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"V\", \"escape\": -0.40770139889048773, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": -0.8152, \"times_seen\": 5.0}, {\"site\": 453, \"mutant\": \"Y\", \"escape\": -0.012282855572181789, \"epitope\": \"epitope 1\", \"reference_site\": \"456\", \"functional effect\": 0.2206, \"times_seen\": 2.0}, {\"site\": 454, \"mutant\": \"G\", \"escape\": 0.039699330646277044, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -2.4922, \"times_seen\": 4.0}, {\"site\": 454, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -3.0652, \"times_seen\": null}, {\"site\": 454, \"mutant\": \"M\", \"escape\": -0.0019004912720840333, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -3.0332, \"times_seen\": 1.0}, {\"site\": 454, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -2.1814, \"times_seen\": null}, {\"site\": 454, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 454, \"mutant\": \"S\", \"escape\": 0.013772852143279307, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": -3.0393, \"times_seen\": 3.0}, {\"site\": 454, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"457\", \"functional effect\": 0.0537, \"times_seen\": null}, {\"site\": 455, \"mutant\": \"E\", \"escape\": -0.02429012634513513, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.1772, \"times_seen\": 10.0}, {\"site\": 455, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 455, \"mutant\": \"L\", \"escape\": -0.00015358861355603003, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.5111, \"times_seen\": 2.0}, {\"site\": 455, \"mutant\": \"M\", \"escape\": 0.0009887992607474402, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.2319, \"times_seen\": 1.0}, {\"site\": 455, \"mutant\": \"N\", \"escape\": -0.009481843929996825, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.0638, \"times_seen\": 17.0}, {\"site\": 455, \"mutant\": \"Q\", \"escape\": 0.1601862792464553, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.1467, \"times_seen\": 10.0}, {\"site\": 455, \"mutant\": \"R\", \"escape\": 0.4274566619157286, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": -0.064, \"times_seen\": 20.0}, {\"site\": 455, \"mutant\": \"S\", \"escape\": -0.007380259596597053, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.3853, \"times_seen\": 5.0}, {\"site\": 455, \"mutant\": \"T\", \"escape\": -0.0018061689444635702, \"epitope\": \"epitope 1\", \"reference_site\": \"458\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 456, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2341, \"times_seen\": null}, {\"site\": 456, \"mutant\": \"F\", \"escape\": -0.017534590623476124, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.7345, \"times_seen\": 15.0}, {\"site\": 456, \"mutant\": \"G\", \"escape\": -0.016561730886214664, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2959, \"times_seen\": 7.0}, {\"site\": 456, \"mutant\": \"I\", \"escape\": 0.0013490751683184559, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.5048, \"times_seen\": 2.0}, {\"site\": 456, \"mutant\": \"K\", \"escape\": 0.04667871468075679, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.3614, \"times_seen\": 5.0}, {\"site\": 456, \"mutant\": \"N\", \"escape\": 0.0208145932477146, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2345, \"times_seen\": 13.0}, {\"site\": 456, \"mutant\": \"P\", \"escape\": -0.0070765633189538, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.5813, \"times_seen\": 2.0}, {\"site\": 456, \"mutant\": \"R\", \"escape\": 0.0031816859029593506, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.1484, \"times_seen\": 3.0}, {\"site\": 456, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 456, \"mutant\": \"Y\", \"escape\": -1.0250809423606604, \"epitope\": \"epitope 1\", \"reference_site\": \"459\", \"functional effect\": -0.2011, \"times_seen\": 4.0}, {\"site\": 457, \"mutant\": \"D\", \"escape\": -0.009603026248529678, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -1.2551, \"times_seen\": 4.0}, {\"site\": 457, \"mutant\": \"I\", \"escape\": -0.02268723121868029, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.0782, \"times_seen\": 2.0}, {\"site\": 457, \"mutant\": \"K\", \"escape\": 0.033435391352301495, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.1905, \"times_seen\": 3.0}, {\"site\": 457, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 457, \"mutant\": \"S\", \"escape\": -1.919140206431945, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.0494, \"times_seen\": 15.0}, {\"site\": 457, \"mutant\": \"T\", \"escape\": -0.04107466717851927, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.3183, \"times_seen\": 8.0}, {\"site\": 457, \"mutant\": \"Y\", \"escape\": 0.005129904893751604, \"epitope\": \"epitope 1\", \"reference_site\": \"460\", \"functional effect\": -0.997, \"times_seen\": 3.0}, {\"site\": 458, \"mutant\": \"I\", \"escape\": 0.01224125295011627, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": 0.4167, \"times_seen\": 1.0}, {\"site\": 458, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 458, \"mutant\": \"M\", \"escape\": -0.0024462698186817583, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -1.7193, \"times_seen\": 1.0}, {\"site\": 458, \"mutant\": \"P\", \"escape\": -0.016735957944434155, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -3.0553, \"times_seen\": 3.0}, {\"site\": 458, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -2.9417, \"times_seen\": null}, {\"site\": 458, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 458, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"461\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 459, \"mutant\": \"E\", \"escape\": -0.05003630286599202, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -0.9144, \"times_seen\": 8.0}, {\"site\": 459, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -1.773, \"times_seen\": null}, {\"site\": 459, \"mutant\": \"I\", \"escape\": -0.014346558826342141, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -2.0544, \"times_seen\": 2.0}, {\"site\": 459, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 459, \"mutant\": \"Q\", \"escape\": -0.011046201245946064, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": -0.027, \"times_seen\": 3.0}, {\"site\": 459, \"mutant\": \"R\", \"escape\": -0.05307777813656352, \"epitope\": \"epitope 1\", \"reference_site\": \"462\", \"functional effect\": 0.245, \"times_seen\": 4.0}, {\"site\": 460, \"mutant\": \"F\", \"escape\": -0.003353484462464733, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -3.0357, \"times_seen\": 1.0}, {\"site\": 460, \"mutant\": \"L\", \"escape\": -0.017028682602013102, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -3.1966, \"times_seen\": 1.0}, {\"site\": 460, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 460, \"mutant\": \"Q\", \"escape\": -0.0017878906370604498, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -1.6084, \"times_seen\": 1.0}, {\"site\": 460, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -3.2747, \"times_seen\": null}, {\"site\": 460, \"mutant\": \"S\", \"escape\": -0.005967793525093259, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -1.9766, \"times_seen\": 8.0}, {\"site\": 460, \"mutant\": \"T\", \"escape\": -0.00764008862497505, \"epitope\": \"epitope 1\", \"reference_site\": \"463\", \"functional effect\": -2.697, \"times_seen\": 2.0}, {\"site\": 461, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 461, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -3.2776, \"times_seen\": null}, {\"site\": 461, \"mutant\": \"L\", \"escape\": 0.0187928181438238, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -1.2792, \"times_seen\": 12.0}, {\"site\": 461, \"mutant\": \"S\", \"escape\": 0.014468932106784614, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -0.6701, \"times_seen\": 1.0}, {\"site\": 461, \"mutant\": \"V\", \"escape\": -0.002620114805668583, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -2.6458, \"times_seen\": 1.0}, {\"site\": 461, \"mutant\": \"Y\", \"escape\": -0.01847764759122065, \"epitope\": \"epitope 1\", \"reference_site\": \"464\", \"functional effect\": -0.29, \"times_seen\": 1.0}, {\"site\": 462, \"mutant\": \"*\", \"escape\": -0.0014620783114026616, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -2.4968, \"times_seen\": 1.0}, {\"site\": 462, \"mutant\": \"A\", \"escape\": -0.01106200847826352, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -1.5638, \"times_seen\": 3.0}, {\"site\": 462, \"mutant\": \"D\", \"escape\": -0.0035676248302055308, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -1.4526, \"times_seen\": 16.0}, {\"site\": 462, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 462, \"mutant\": \"G\", \"escape\": -0.013234493288030879, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -1.101, \"times_seen\": 9.0}, {\"site\": 462, \"mutant\": \"K\", \"escape\": -0.012306245745263292, \"epitope\": \"epitope 1\", \"reference_site\": \"465\", \"functional effect\": -2.4745, \"times_seen\": 2.0}, {\"site\": 463, \"mutant\": \"G\", \"escape\": -0.0019172265598252573, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -2.7086, \"times_seen\": 2.0}, {\"site\": 463, \"mutant\": \"I\", \"escape\": -0.0038263306005395653, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -2.6585, \"times_seen\": 1.0}, {\"site\": 463, \"mutant\": \"K\", \"escape\": 0.008543201008986959, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -0.9854, \"times_seen\": 6.0}, {\"site\": 463, \"mutant\": \"M\", \"escape\": -0.03486717995069199, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -1.8776, \"times_seen\": 8.0}, {\"site\": 463, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 463, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -3.1059, \"times_seen\": null}, {\"site\": 463, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"466\", \"functional effect\": -3.0058, \"times_seen\": null}, {\"site\": 464, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 464, \"mutant\": \"E\", \"escape\": 2.7075723275332015e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.7075, \"times_seen\": 1.0}, {\"site\": 464, \"mutant\": \"G\", \"escape\": 0.017913413736770092, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.9013, \"times_seen\": 1.0}, {\"site\": 464, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.9555, \"times_seen\": null}, {\"site\": 464, \"mutant\": \"N\", \"escape\": -0.0037287291151327493, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.6267, \"times_seen\": 1.0}, {\"site\": 464, \"mutant\": \"Y\", \"escape\": -0.0027858734554690474, \"epitope\": \"epitope 1\", \"reference_site\": \"467\", \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 465, \"mutant\": \"F\", \"escape\": 0.01606793693544998, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -2.1352, \"times_seen\": 2.0}, {\"site\": 465, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 465, \"mutant\": \"L\", \"escape\": 0.09973159136321459, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.349, \"times_seen\": 5.0}, {\"site\": 465, \"mutant\": \"M\", \"escape\": 0.015944363358081925, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.6158, \"times_seen\": 1.0}, {\"site\": 465, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -1.9626, \"times_seen\": null}, {\"site\": 465, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.5777, \"times_seen\": null}, {\"site\": 465, \"mutant\": \"T\", \"escape\": 0.019134332935156446, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.4385, \"times_seen\": 23.0}, {\"site\": 465, \"mutant\": \"V\", \"escape\": 0.006707181410463662, \"epitope\": \"epitope 1\", \"reference_site\": \"468\", \"functional effect\": -0.6714, \"times_seen\": 9.0}, {\"site\": 466, \"mutant\": \"A\", \"escape\": 0.003170388502523435, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -1.8312, \"times_seen\": 6.0}, {\"site\": 466, \"mutant\": \"G\", \"escape\": -0.08809366661910253, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -0.6392, \"times_seen\": 12.0}, {\"site\": 466, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -2.7969, \"times_seen\": null}, {\"site\": 466, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -1.23, \"times_seen\": null}, {\"site\": 466, \"mutant\": \"N\", \"escape\": -0.05552505591088101, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -0.7065, \"times_seen\": 31.0}, {\"site\": 466, \"mutant\": \"R\", \"escape\": -0.00509873546672898, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": -2.4014, \"times_seen\": 1.0}, {\"site\": 466, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"469\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 467, \"mutant\": \"A\", \"escape\": -0.009441887436754573, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.3892, \"times_seen\": 6.0}, {\"site\": 467, \"mutant\": \"I\", \"escape\": 0.09496392448085852, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.5468, \"times_seen\": 43.0}, {\"site\": 467, \"mutant\": \"K\", \"escape\": 0.8570948158265903, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.5988, \"times_seen\": 5.0}, {\"site\": 467, \"mutant\": \"N\", \"escape\": -0.014385605142072495, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": 0.0284, \"times_seen\": 33.0}, {\"site\": 467, \"mutant\": \"R\", \"escape\": 0.00836437285188616, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": 0.3772, \"times_seen\": 7.0}, {\"site\": 467, \"mutant\": \"S\", \"escape\": 0.0033908650395462884, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": -0.8349, \"times_seen\": 6.0}, {\"site\": 467, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"470\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 468, \"mutant\": \"*\", \"escape\": -0.003487999150390316, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -2.4359, \"times_seen\": 1.0}, {\"site\": 468, \"mutant\": \"A\", \"escape\": -0.004665686527945577, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.5909, \"times_seen\": 6.0}, {\"site\": 468, \"mutant\": \"D\", \"escape\": 0.004642112976943978, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.101, \"times_seen\": 12.0}, {\"site\": 468, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 468, \"mutant\": \"G\", \"escape\": 0.07638248832955141, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.7486, \"times_seen\": 23.0}, {\"site\": 468, \"mutant\": \"K\", \"escape\": -0.022984827149819056, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -1.4314, \"times_seen\": 13.0}, {\"site\": 468, \"mutant\": \"Q\", \"escape\": -0.06826328621601101, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.2862, \"times_seen\": 41.0}, {\"site\": 468, \"mutant\": \"V\", \"escape\": 0.014295906680980313, \"epitope\": \"epitope 1\", \"reference_site\": \"471\", \"functional effect\": -0.6964, \"times_seen\": 6.0}, {\"site\": 469, \"mutant\": \"F\", \"escape\": 0.05194189178261557, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -0.9636, \"times_seen\": 4.0}, {\"site\": 469, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 469, \"mutant\": \"L\", \"escape\": -0.009252566437485059, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": 0.1237, \"times_seen\": 5.0}, {\"site\": 469, \"mutant\": \"M\", \"escape\": 0.0015376048217024972, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": 0.0321, \"times_seen\": 1.0}, {\"site\": 469, \"mutant\": \"N\", \"escape\": -0.004773214787807928, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 469, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -0.5576, \"times_seen\": null}, {\"site\": 469, \"mutant\": \"T\", \"escape\": 0.02555949669996331, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -1.1749, \"times_seen\": 18.0}, {\"site\": 469, \"mutant\": \"V\", \"escape\": -0.001694612558655493, \"epitope\": \"epitope 1\", \"reference_site\": \"472\", \"functional effect\": -0.4416, \"times_seen\": 9.0}, {\"site\": 470, \"mutant\": \"*\", \"escape\": -0.006272904947881412, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -2.7598, \"times_seen\": 2.0}, {\"site\": 470, \"mutant\": \"C\", \"escape\": -0.03933099206259502, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -2.3124, \"times_seen\": 1.0}, {\"site\": 470, \"mutant\": \"F\", \"escape\": 0.03266256462377902, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": 0.0095, \"times_seen\": 16.0}, {\"site\": 470, \"mutant\": \"H\", \"escape\": -0.01917634020279748, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -0.6, \"times_seen\": 7.0}, {\"site\": 470, \"mutant\": \"N\", \"escape\": -0.002740333148685893, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": -1.6109, \"times_seen\": 1.0}, {\"site\": 470, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"473\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 471, \"mutant\": \"*\", \"escape\": -0.000126406463148657, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -2.3923, \"times_seen\": 1.0}, {\"site\": 471, \"mutant\": \"E\", \"escape\": 0.4354978816368362, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -0.3826, \"times_seen\": 6.0}, {\"site\": 471, \"mutant\": \"H\", \"escape\": -0.2742682155091341, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -1.3723, \"times_seen\": 11.0}, {\"site\": 471, \"mutant\": \"K\", \"escape\": -0.002481148237002242, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -1.1986, \"times_seen\": 7.0}, {\"site\": 471, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -0.8613, \"times_seen\": null}, {\"site\": 471, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 471, \"mutant\": \"R\", \"escape\": 0.0047099672320383736, \"epitope\": \"epitope 1\", \"reference_site\": \"474\", \"functional effect\": -1.3102, \"times_seen\": 29.0}, {\"site\": 472, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 472, \"mutant\": \"D\", \"escape\": 0.014805800637940805, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -1.0243, \"times_seen\": 9.0}, {\"site\": 472, \"mutant\": \"L\", \"escape\": -0.00965907689955572, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.6215, \"times_seen\": 4.0}, {\"site\": 472, \"mutant\": \"S\", \"escape\": -0.1588169189851842, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.4959, \"times_seen\": 19.0}, {\"site\": 472, \"mutant\": \"T\", \"escape\": -0.04848802670693783, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.6461, \"times_seen\": 23.0}, {\"site\": 472, \"mutant\": \"V\", \"escape\": -0.0968482484664744, \"epitope\": \"epitope 1\", \"reference_site\": \"475\", \"functional effect\": -0.1795, \"times_seen\": 17.0}, {\"site\": 473, \"mutant\": \"A\", \"escape\": -0.021609155984226826, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -0.5457, \"times_seen\": 7.0}, {\"site\": 473, \"mutant\": \"C\", \"escape\": -0.003452799162038559, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -2.2789, \"times_seen\": 1.0}, {\"site\": 473, \"mutant\": \"D\", \"escape\": -0.05251928708755486, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -0.7248, \"times_seen\": 44.0}, {\"site\": 473, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 473, \"mutant\": \"K\", \"escape\": -0.004817149591528679, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -2.7481, \"times_seen\": 2.0}, {\"site\": 473, \"mutant\": \"S\", \"escape\": -0.03772534245646802, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 473, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"476\", \"functional effect\": -2.9062, \"times_seen\": null}, {\"site\": 474, \"mutant\": \"*\", \"escape\": -0.01699709084084499, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -2.7271, \"times_seen\": 1.0}, {\"site\": 474, \"mutant\": \"-\", \"escape\": -0.004208673370902456, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 474, \"mutant\": \"A\", \"escape\": -0.016416925499979456, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5291, \"times_seen\": 7.0}, {\"site\": 474, \"mutant\": \"C\", \"escape\": -0.006050406165921933, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -2.4417, \"times_seen\": 2.0}, {\"site\": 474, \"mutant\": \"D\", \"escape\": -0.029455947162548422, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.3592, \"times_seen\": 13.0}, {\"site\": 474, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.4453, \"times_seen\": null}, {\"site\": 474, \"mutant\": \"F\", \"escape\": -0.01048767351927239, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.6824, \"times_seen\": 3.0}, {\"site\": 474, \"mutant\": \"G\", \"escape\": -0.04948697260850793, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.3226, \"times_seen\": 16.0}, {\"site\": 474, \"mutant\": \"H\", \"escape\": -0.019773804590737944, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.1796, \"times_seen\": 7.0}, {\"site\": 474, \"mutant\": \"I\", \"escape\": -0.03383285537816778, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.2299, \"times_seen\": 23.0}, {\"site\": 474, \"mutant\": \"K\", \"escape\": 0.03741271787362503, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0419, \"times_seen\": 17.0}, {\"site\": 474, \"mutant\": \"L\", \"escape\": -0.0014086204640798889, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5132, \"times_seen\": 12.0}, {\"site\": 474, \"mutant\": \"M\", \"escape\": -0.005268340392800772, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5954, \"times_seen\": 5.0}, {\"site\": 474, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 474, \"mutant\": \"P\", \"escape\": 0.0022765512632641066, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.1628, \"times_seen\": 19.0}, {\"site\": 474, \"mutant\": \"Q\", \"escape\": -0.02897465915476644, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0043, \"times_seen\": 7.0}, {\"site\": 474, \"mutant\": \"R\", \"escape\": -0.017182300496865283, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.5627, \"times_seen\": 18.0}, {\"site\": 474, \"mutant\": \"S\", \"escape\": -0.4196440246646401, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0281, \"times_seen\": 46.0}, {\"site\": 474, \"mutant\": \"T\", \"escape\": -0.06894551104698483, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.0542, \"times_seen\": 47.0}, {\"site\": 474, \"mutant\": \"V\", \"escape\": -0.02943269470636828, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": 0.0493, \"times_seen\": 9.0}, {\"site\": 474, \"mutant\": \"W\", \"escape\": -0.003947269516557137, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -1.0221, \"times_seen\": 1.0}, {\"site\": 474, \"mutant\": \"Y\", \"escape\": -0.04721824295262623, \"epitope\": \"epitope 1\", \"reference_site\": \"477\", \"functional effect\": -0.9565, \"times_seen\": 11.0}, {\"site\": 475, \"mutant\": \"*\", \"escape\": -0.017162950875128178, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -3.0352, \"times_seen\": 4.0}, {\"site\": 475, \"mutant\": \"-\", \"escape\": -0.004127508849649172, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 475, \"mutant\": \"A\", \"escape\": 0.006976137315861006, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1629, \"times_seen\": 17.0}, {\"site\": 475, \"mutant\": \"C\", \"escape\": -0.0042956367163029556, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -2.4135, \"times_seen\": 1.0}, {\"site\": 475, \"mutant\": \"D\", \"escape\": 0.002613090235620465, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1663, \"times_seen\": 4.0}, {\"site\": 475, \"mutant\": \"E\", \"escape\": -1.581183352913258, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.1619, \"times_seen\": 23.0}, {\"site\": 475, \"mutant\": \"F\", \"escape\": -0.01077493621694332, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.3474, \"times_seen\": 6.0}, {\"site\": 475, \"mutant\": \"G\", \"escape\": -0.036773479300496716, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.5754, \"times_seen\": 15.0}, {\"site\": 475, \"mutant\": \"H\", \"escape\": -0.02709197815218699, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.104, \"times_seen\": 12.0}, {\"site\": 475, \"mutant\": \"I\", \"escape\": 0.3911907810199889, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.2191, \"times_seen\": 25.0}, {\"site\": 475, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 475, \"mutant\": \"L\", \"escape\": -0.008915241102822902, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1538, \"times_seen\": 18.0}, {\"site\": 475, \"mutant\": \"M\", \"escape\": -0.022326814107138115, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.2939, \"times_seen\": 20.0}, {\"site\": 475, \"mutant\": \"N\", \"escape\": -0.011194154274751119, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.2213, \"times_seen\": 26.0}, {\"site\": 475, \"mutant\": \"P\", \"escape\": 0.03734230661156104, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -2.0058, \"times_seen\": 6.0}, {\"site\": 475, \"mutant\": \"Q\", \"escape\": 0.009707134029107603, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.1862, \"times_seen\": 12.0}, {\"site\": 475, \"mutant\": \"R\", \"escape\": -0.1954345782438452, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1985, \"times_seen\": 66.0}, {\"site\": 475, \"mutant\": \"S\", \"escape\": -0.05527287180102221, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.0548, \"times_seen\": 28.0}, {\"site\": 475, \"mutant\": \"T\", \"escape\": -0.11802746522878665, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.1097, \"times_seen\": 40.0}, {\"site\": 475, \"mutant\": \"V\", \"escape\": -0.04261243087312703, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": 0.084, \"times_seen\": 22.0}, {\"site\": 475, \"mutant\": \"W\", \"escape\": -0.010519751842623685, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -1.0061, \"times_seen\": 11.0}, {\"site\": 475, \"mutant\": \"Y\", \"escape\": 0.0768409192620355, \"epitope\": \"epitope 1\", \"reference_site\": \"478\", \"functional effect\": -0.1538, \"times_seen\": 11.0}, {\"site\": 476, \"mutant\": \"-\", \"escape\": -0.012749755186603111, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 476, \"mutant\": \"A\", \"escape\": 0.004354418571891856, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.5907, \"times_seen\": 6.0}, {\"site\": 476, \"mutant\": \"H\", \"escape\": -0.013406424014139552, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.8606, \"times_seen\": 19.0}, {\"site\": 476, \"mutant\": \"L\", \"escape\": -2.0013098194231715, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.9326, \"times_seen\": 15.0}, {\"site\": 476, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.7712, \"times_seen\": null}, {\"site\": 476, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 476, \"mutant\": \"Q\", \"escape\": -0.036158392663184415, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.2531, \"times_seen\": 10.0}, {\"site\": 476, \"mutant\": \"R\", \"escape\": -0.008158744268741013, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.6761, \"times_seen\": 1.0}, {\"site\": 476, \"mutant\": \"S\", \"escape\": -0.9597784244920206, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": 0.0541, \"times_seen\": 19.0}, {\"site\": 476, \"mutant\": \"T\", \"escape\": -0.000613431160911465, \"epitope\": \"epitope 1\", \"reference_site\": \"479\", \"functional effect\": -0.0611, \"times_seen\": 14.0}, {\"site\": 477, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.9991, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"-\", \"escape\": -0.0025462251368446615, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 477, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.5488, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.9173, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.9774, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"Y\", \"escape\": 0.01773878774268679, \"epitope\": \"epitope 1\", \"reference_site\": \"480\", \"functional effect\": -2.6892, \"times_seen\": 1.0}, {\"site\": 478, \"mutant\": \"D\", \"escape\": -0.028889634281185794, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.1436, \"times_seen\": 25.0}, {\"site\": 478, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 478, \"mutant\": \"H\", \"escape\": -0.01322712405990078, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.2157, \"times_seen\": 10.0}, {\"site\": 478, \"mutant\": \"I\", \"escape\": -0.01127533273997746, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -2.158, \"times_seen\": 3.0}, {\"site\": 478, \"mutant\": \"K\", \"escape\": -0.010297213719331464, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.2804, \"times_seen\": 70.0}, {\"site\": 478, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 478, \"mutant\": \"S\", \"escape\": -0.33064029274513973, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.4046, \"times_seen\": 38.0}, {\"site\": 478, \"mutant\": \"Y\", \"escape\": -0.023159430364693916, \"epitope\": \"epitope 1\", \"reference_site\": \"481\", \"functional effect\": -0.2739, \"times_seen\": 10.0}, {\"site\": 479, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -3.0998, \"times_seen\": null}, {\"site\": 479, \"mutant\": \"D\", \"escape\": -0.3160688955514735, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.4916, \"times_seen\": 36.0}, {\"site\": 479, \"mutant\": \"E\", \"escape\": -0.04046797237897144, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.67, \"times_seen\": 10.0}, {\"site\": 479, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 479, \"mutant\": \"R\", \"escape\": -0.009535493158696626, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.9962, \"times_seen\": 8.0}, {\"site\": 479, \"mutant\": \"S\", \"escape\": -0.006580653425902866, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -0.7021, \"times_seen\": 30.0}, {\"site\": 479, \"mutant\": \"V\", \"escape\": -0.059586460399885535, \"epitope\": \"epitope 1\", \"reference_site\": \"482\", \"functional effect\": -1.8789, \"times_seen\": 17.0}, {\"site\": 480, \"mutant\": \"A\", \"escape\": 0.05123691790484491, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.1605, \"times_seen\": 4.0}, {\"site\": 480, \"mutant\": \"E\", \"escape\": 0.015315479515728632, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.1194, \"times_seen\": 2.0}, {\"site\": 480, \"mutant\": \"F\", \"escape\": -0.015647255308761956, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.843, \"times_seen\": 17.0}, {\"site\": 480, \"mutant\": \"G\", \"escape\": -0.01385111162353594, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.3308, \"times_seen\": 7.0}, {\"site\": 480, \"mutant\": \"I\", \"escape\": 0.015279873577149182, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": 0.0897, \"times_seen\": 17.0}, {\"site\": 480, \"mutant\": \"L\", \"escape\": -0.11094889170955274, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": -0.1138, \"times_seen\": 31.0}, {\"site\": 480, \"mutant\": \"M\", \"escape\": -0.0012717399493233097, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": 0.042, \"times_seen\": 8.0}, {\"site\": 480, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"483\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 481, \"mutant\": \"*\", \"escape\": -0.0036580076114327903, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -2.7147, \"times_seen\": 1.0}, {\"site\": 481, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 481, \"mutant\": \"C\", \"escape\": 0.016037157758105387, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -2.9819, \"times_seen\": 4.0}, {\"site\": 481, \"mutant\": \"D\", \"escape\": 0.021878145747144705, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -1.4618, \"times_seen\": 36.0}, {\"site\": 481, \"mutant\": \"E\", \"escape\": 0.13050279837870113, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.2489, \"times_seen\": 20.0}, {\"site\": 481, \"mutant\": \"F\", \"escape\": -0.0427511627995259, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.8377, \"times_seen\": 14.0}, {\"site\": 481, \"mutant\": \"G\", \"escape\": -0.16766177144590053, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.696, \"times_seen\": 50.0}, {\"site\": 481, \"mutant\": \"H\", \"escape\": 0.06653754709321832, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.6341, \"times_seen\": 14.0}, {\"site\": 481, \"mutant\": \"I\", \"escape\": -0.030106782268263223, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.1683, \"times_seen\": 10.0}, {\"site\": 481, \"mutant\": \"K\", \"escape\": -0.04460226662946424, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.3417, \"times_seen\": 18.0}, {\"site\": 481, \"mutant\": \"L\", \"escape\": -0.06779786449973045, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.1515, \"times_seen\": 32.0}, {\"site\": 481, \"mutant\": \"M\", \"escape\": -0.0041929536293434, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.3964, \"times_seen\": 5.0}, {\"site\": 481, \"mutant\": \"N\", \"escape\": -0.05802112578413213, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.7223, \"times_seen\": 19.0}, {\"site\": 481, \"mutant\": \"P\", \"escape\": 0.014852565326470763, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": 0.0548, \"times_seen\": 56.0}, {\"site\": 481, \"mutant\": \"Q\", \"escape\": 0.0394893025246893, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.136, \"times_seen\": 18.0}, {\"site\": 481, \"mutant\": \"R\", \"escape\": 0.07410442483928134, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.2489, \"times_seen\": 33.0}, {\"site\": 481, \"mutant\": \"S\", \"escape\": -0.17668524165014907, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.2204, \"times_seen\": 55.0}, {\"site\": 481, \"mutant\": \"T\", \"escape\": 0.05780361614816999, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": 0.0389, \"times_seen\": 84.0}, {\"site\": 481, \"mutant\": \"V\", \"escape\": -0.00772252317267667, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -0.0617, \"times_seen\": 67.0}, {\"site\": 481, \"mutant\": \"W\", \"escape\": -0.01187612972528075, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -2.5984, \"times_seen\": 4.0}, {\"site\": 481, \"mutant\": \"Y\", \"escape\": 0.011039012905433427, \"epitope\": \"epitope 1\", \"reference_site\": \"484\", \"functional effect\": -1.1779, \"times_seen\": 13.0}, {\"site\": 482, \"mutant\": \"A\", \"escape\": -0.05730336820735137, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.7599, \"times_seen\": 32.0}, {\"site\": 482, \"mutant\": \"C\", \"escape\": -0.0027666406032981995, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -1.7725, \"times_seen\": 1.0}, {\"site\": 482, \"mutant\": \"D\", \"escape\": 0.3468755254985673, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.4621, \"times_seen\": 34.0}, {\"site\": 482, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 482, \"mutant\": \"R\", \"escape\": -0.02422527279273003, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -1.2887, \"times_seen\": 11.0}, {\"site\": 482, \"mutant\": \"S\", \"escape\": -0.13214692250368085, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.1985, \"times_seen\": 40.0}, {\"site\": 482, \"mutant\": \"T\", \"escape\": -0.003168971695907818, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -0.7847, \"times_seen\": 1.0}, {\"site\": 482, \"mutant\": \"V\", \"escape\": 0.050861134153290195, \"epitope\": \"epitope 1\", \"reference_site\": \"485\", \"functional effect\": -1.5063, \"times_seen\": 11.0}, {\"site\": 483, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 483, \"mutant\": \"I\", \"escape\": -0.07263853475913927, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.0929, \"times_seen\": 15.0}, {\"site\": 483, \"mutant\": \"L\", \"escape\": -1.0477657671914942, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.1442, \"times_seen\": 15.0}, {\"site\": 483, \"mutant\": \"S\", \"escape\": -0.20031988936382725, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": 0.1937, \"times_seen\": 40.0}, {\"site\": 483, \"mutant\": \"V\", \"escape\": -0.039684921315882166, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": -0.0454, \"times_seen\": 9.0}, {\"site\": 483, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"486\", \"functional effect\": -0.1748, \"times_seen\": null}, {\"site\": 484, \"mutant\": \"D\", \"escape\": -0.0031354379405887623, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": 0.3125, \"times_seen\": 1.0}, {\"site\": 484, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 484, \"mutant\": \"I\", \"escape\": -0.009400324754222976, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -2.8443, \"times_seen\": 3.0}, {\"site\": 484, \"mutant\": \"K\", \"escape\": -0.019088270132489513, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -0.32, \"times_seen\": 7.0}, {\"site\": 484, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 484, \"mutant\": \"S\", \"escape\": 0.010657236293399217, \"epitope\": \"epitope 1\", \"reference_site\": \"487\", \"functional effect\": -0.3665, \"times_seen\": 3.0}, {\"site\": 485, \"mutant\": \"*\", \"escape\": -0.02323168598797415, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.9821, \"times_seen\": 2.0}, {\"site\": 485, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.7516, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.951, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"L\", \"escape\": -1.6716737954480252, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -3.08, \"times_seen\": 1.0}, {\"site\": 485, \"mutant\": \"R\", \"escape\": -0.022706539757637333, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.961, \"times_seen\": 3.0}, {\"site\": 485, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": 0.2729, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.9789, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"W\", \"escape\": -0.017000699720364457, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.8571, \"times_seen\": 1.0}, {\"site\": 485, \"mutant\": \"Y\", \"escape\": -0.028425932120894195, \"epitope\": \"epitope 1\", \"reference_site\": \"488\", \"functional effect\": -2.3412, \"times_seen\": 4.0}, {\"site\": 486, \"mutant\": \"*\", \"escape\": -0.01000273454299407, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -2.3672, \"times_seen\": 1.0}, {\"site\": 486, \"mutant\": \"C\", \"escape\": -0.04840438028000326, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -1.0498, \"times_seen\": 1.0}, {\"site\": 486, \"mutant\": \"D\", \"escape\": -0.01012489939936397, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -1.714, \"times_seen\": 1.0}, {\"site\": 486, \"mutant\": \"H\", \"escape\": -1.2085308330019164, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -0.2363, \"times_seen\": 37.0}, {\"site\": 486, \"mutant\": \"L\", \"escape\": -0.009680335922001381, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -0.4084, \"times_seen\": 2.0}, {\"site\": 486, \"mutant\": \"W\", \"escape\": -0.039655523890389566, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": -0.3635, \"times_seen\": 4.0}, {\"site\": 486, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"489\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"I\", \"escape\": 0.00984963960712549, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.5613, \"times_seen\": 3.0}, {\"site\": 487, \"mutant\": \"L\", \"escape\": -0.029694004670272462, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.6844, \"times_seen\": 10.0}, {\"site\": 487, \"mutant\": \"R\", \"escape\": -0.00555903573988958, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -2.5252, \"times_seen\": 2.0}, {\"site\": 487, \"mutant\": \"S\", \"escape\": -0.005827825569916732, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.2581, \"times_seen\": 6.0}, {\"site\": 487, \"mutant\": \"V\", \"escape\": -0.010445606476482659, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": -0.0441, \"times_seen\": 2.0}, {\"site\": 487, \"mutant\": \"Y\", \"escape\": 0.0008663147958281049, \"epitope\": \"epitope 1\", \"reference_site\": \"490\", \"functional effect\": 0.0991, \"times_seen\": 11.0}, {\"site\": 488, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 488, \"mutant\": \"L\", \"escape\": -0.01531558434838118, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -1.8109, \"times_seen\": 3.0}, {\"site\": 488, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 488, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 488, \"mutant\": \"S\", \"escape\": -0.0037805088225480185, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -3.0999, \"times_seen\": 1.0}, {\"site\": 488, \"mutant\": \"T\", \"escape\": -0.003075903871290668, \"epitope\": \"epitope 1\", \"reference_site\": \"491\", \"functional effect\": -2.9169, \"times_seen\": 1.0}, {\"site\": 489, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"F\", \"escape\": -0.017294313204511465, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -2.4022, \"times_seen\": 4.0}, {\"site\": 489, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -3.2591, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"I\", \"escape\": 0.000589799532044327, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -1.0383, \"times_seen\": 1.0}, {\"site\": 489, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"P\", \"escape\": -0.01047494147300837, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -1.8611, \"times_seen\": 2.0}, {\"site\": 489, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -1.4113, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"492\", \"functional effect\": -2.4571, \"times_seen\": null}, {\"site\": 490, \"mutant\": \"*\", \"escape\": -0.004461837791976207, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.5897, \"times_seen\": 2.0}, {\"site\": 490, \"mutant\": \"A\", \"escape\": 0.10205869050002542, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.3866, \"times_seen\": 45.0}, {\"site\": 490, \"mutant\": \"C\", \"escape\": -0.01939358940210577, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.3533, \"times_seen\": 3.0}, {\"site\": 490, \"mutant\": \"D\", \"escape\": 0.011546396064872868, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.5278, \"times_seen\": 7.0}, {\"site\": 490, \"mutant\": \"E\", \"escape\": 0.14594406578911012, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.2944, \"times_seen\": 16.0}, {\"site\": 490, \"mutant\": \"F\", \"escape\": -0.020536667226600296, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.0279, \"times_seen\": 2.0}, {\"site\": 490, \"mutant\": \"G\", \"escape\": -0.05231061507612354, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.9766, \"times_seen\": 42.0}, {\"site\": 490, \"mutant\": \"H\", \"escape\": -0.1106935150170098, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.7874, \"times_seen\": 46.0}, {\"site\": 490, \"mutant\": \"I\", \"escape\": 0.016256808728356997, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.119, \"times_seen\": 7.0}, {\"site\": 490, \"mutant\": \"K\", \"escape\": 0.03485430666440265, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.0552, \"times_seen\": 34.0}, {\"site\": 490, \"mutant\": \"L\", \"escape\": -0.010819043679151558, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.6339, \"times_seen\": 30.0}, {\"site\": 490, \"mutant\": \"M\", \"escape\": 0.029379011133464146, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.8017, \"times_seen\": 6.0}, {\"site\": 490, \"mutant\": \"N\", \"escape\": 0.008016290657410594, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.746, \"times_seen\": 5.0}, {\"site\": 490, \"mutant\": \"P\", \"escape\": -0.009731126298183804, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -2.6584, \"times_seen\": 5.0}, {\"site\": 490, \"mutant\": \"Q\", \"escape\": 0.10302157594135752, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.2715, \"times_seen\": 26.0}, {\"site\": 490, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 490, \"mutant\": \"S\", \"escape\": 0.014762528431790102, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.6663, \"times_seen\": 45.0}, {\"site\": 490, \"mutant\": \"T\", \"escape\": 0.004965769031248267, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.8249, \"times_seen\": 22.0}, {\"site\": 490, \"mutant\": \"V\", \"escape\": 0.7216476167586461, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -0.7732, \"times_seen\": 34.0}, {\"site\": 490, \"mutant\": \"W\", \"escape\": -0.04851721601294354, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.7173, \"times_seen\": 2.0}, {\"site\": 490, \"mutant\": \"Y\", \"escape\": -0.013246571927468276, \"epitope\": \"epitope 1\", \"reference_site\": \"493\", \"functional effect\": -1.2071, \"times_seen\": 13.0}, {\"site\": 491, \"mutant\": \"A\", \"escape\": 0.030308536340083778, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.1818, \"times_seen\": 3.0}, {\"site\": 491, \"mutant\": \"F\", \"escape\": 0.020405221687678145, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -1.5274, \"times_seen\": 2.0}, {\"site\": 491, \"mutant\": \"L\", \"escape\": 3.0490928290327566, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -1.0881, \"times_seen\": 11.0}, {\"site\": 491, \"mutant\": \"P\", \"escape\": 0.029319123587839894, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.5503, \"times_seen\": 23.0}, {\"site\": 491, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 491, \"mutant\": \"T\", \"escape\": 0.0028229991581962327, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.1058, \"times_seen\": 11.0}, {\"site\": 491, \"mutant\": \"Y\", \"escape\": 1.4841234683694373, \"epitope\": \"epitope 1\", \"reference_site\": \"494\", \"functional effect\": -0.9805, \"times_seen\": 5.0}, {\"site\": 492, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 492, \"mutant\": \"-\", \"escape\": -0.00682587313521693, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 492, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.3157, \"times_seen\": null}, {\"site\": 492, \"mutant\": \"H\", \"escape\": 0.007302413377597479, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.3786, \"times_seen\": 8.0}, {\"site\": 492, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.2545, \"times_seen\": null}, {\"site\": 492, \"mutant\": \"W\", \"escape\": -0.0018781979991266194, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": -2.1345, \"times_seen\": 1.0}, {\"site\": 492, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"495\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 493, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -3.0079, \"times_seen\": null}, {\"site\": 493, \"mutant\": \"-\", \"escape\": -0.0018849223908266259, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 493, \"mutant\": \"A\", \"escape\": -0.11850666298219076, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0471, \"times_seen\": 44.0}, {\"site\": 493, \"mutant\": \"C\", \"escape\": -0.033402770180627435, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -1.1981, \"times_seen\": 31.0}, {\"site\": 493, \"mutant\": \"D\", \"escape\": -0.09401769367697349, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.2573, \"times_seen\": 29.0}, {\"site\": 493, \"mutant\": \"E\", \"escape\": 0.08952946401543874, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.4075, \"times_seen\": 3.0}, {\"site\": 493, \"mutant\": \"F\", \"escape\": 0.1009154813599887, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.6332, \"times_seen\": 19.0}, {\"site\": 493, \"mutant\": \"G\", \"escape\": -0.42674514535523195, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0404, \"times_seen\": 50.0}, {\"site\": 493, \"mutant\": \"H\", \"escape\": 0.06463461901301527, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.0759, \"times_seen\": 23.0}, {\"site\": 493, \"mutant\": \"I\", \"escape\": 0.01690930575742059, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.1474, \"times_seen\": 33.0}, {\"site\": 493, \"mutant\": \"K\", \"escape\": 2.3300544311162388, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.6137, \"times_seen\": 7.0}, {\"site\": 493, \"mutant\": \"L\", \"escape\": 0.3571301608130763, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.5501, \"times_seen\": 34.0}, {\"site\": 493, \"mutant\": \"M\", \"escape\": -0.6424761336574455, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.1907, \"times_seen\": 7.0}, {\"site\": 493, \"mutant\": \"N\", \"escape\": 1.42281035906515, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.1379, \"times_seen\": 47.0}, {\"site\": 493, \"mutant\": \"P\", \"escape\": 0.0058058385235967595, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -2.2628, \"times_seen\": 13.0}, {\"site\": 493, \"mutant\": \"Q\", \"escape\": -0.01085014366957989, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0007, \"times_seen\": 5.0}, {\"site\": 493, \"mutant\": \"R\", \"escape\": 1.7466480153687878, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -1.4775, \"times_seen\": 39.0}, {\"site\": 493, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 493, \"mutant\": \"T\", \"escape\": -0.9561257219027219, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": 0.0331, \"times_seen\": 36.0}, {\"site\": 493, \"mutant\": \"V\", \"escape\": -0.2156084483472283, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.1352, \"times_seen\": 46.0}, {\"site\": 493, \"mutant\": \"W\", \"escape\": -0.02197253411259539, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -1.3651, \"times_seen\": 7.0}, {\"site\": 493, \"mutant\": \"Y\", \"escape\": 1.4281961137488555, \"epitope\": \"epitope 1\", \"reference_site\": \"496\", \"functional effect\": -0.4377, \"times_seen\": 12.0}, {\"site\": 494, \"mutant\": \"-\", \"escape\": -0.006256036718114187, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 494, \"mutant\": \"H\", \"escape\": -0.0007527054778415932, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -2.6818, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"L\", \"escape\": -0.09270974779481096, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -2.4924, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"S\", \"escape\": -0.0035029596332667484, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -2.9094, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 494, \"mutant\": \"W\", \"escape\": 0.0336601347339089, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -0.8619, \"times_seen\": 6.0}, {\"site\": 494, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"497\", \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 495, \"mutant\": \"*\", \"escape\": 0.024267830207389273, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -2.4975, \"times_seen\": 2.0}, {\"site\": 495, \"mutant\": \"-\", \"escape\": -0.0022832226338924417, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 495, \"mutant\": \"A\", \"escape\": -0.011890561369744, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.043, \"times_seen\": 5.0}, {\"site\": 495, \"mutant\": \"C\", \"escape\": -0.004347887656106837, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -2.4122, \"times_seen\": 1.0}, {\"site\": 495, \"mutant\": \"D\", \"escape\": 0.017508478331906663, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.7782, \"times_seen\": 2.0}, {\"site\": 495, \"mutant\": \"E\", \"escape\": 0.01582178863336817, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.2172, \"times_seen\": 9.0}, {\"site\": 495, \"mutant\": \"F\", \"escape\": 0.0022951711404849205, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.0421, \"times_seen\": 11.0}, {\"site\": 495, \"mutant\": \"G\", \"escape\": -0.09095526397415192, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.3789, \"times_seen\": 28.0}, {\"site\": 495, \"mutant\": \"H\", \"escape\": -0.02873767493323251, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.2841, \"times_seen\": 10.0}, {\"site\": 495, \"mutant\": \"I\", \"escape\": -0.028787526627020842, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.1404, \"times_seen\": 9.0}, {\"site\": 495, \"mutant\": \"K\", \"escape\": -0.0311489794854924, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.1592, \"times_seen\": 24.0}, {\"site\": 495, \"mutant\": \"L\", \"escape\": -0.006372724451308909, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.3126, \"times_seen\": 16.0}, {\"site\": 495, \"mutant\": \"M\", \"escape\": -0.06754380616542427, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.1347, \"times_seen\": 15.0}, {\"site\": 495, \"mutant\": \"N\", \"escape\": 0.0053867961693047075, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.0844, \"times_seen\": 5.0}, {\"site\": 495, \"mutant\": \"P\", \"escape\": -0.0014075811152365106, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -2.7657, \"times_seen\": 1.0}, {\"site\": 495, \"mutant\": \"Q\", \"escape\": 0.01654726204349885, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.0442, \"times_seen\": 8.0}, {\"site\": 495, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 495, \"mutant\": \"S\", \"escape\": -0.06324573514710494, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": 0.0007, \"times_seen\": 13.0}, {\"site\": 495, \"mutant\": \"T\", \"escape\": -0.03443436399378494, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.1952, \"times_seen\": 12.0}, {\"site\": 495, \"mutant\": \"V\", \"escape\": -0.0312601228368731, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.2869, \"times_seen\": 12.0}, {\"site\": 495, \"mutant\": \"W\", \"escape\": 5.015076002086121, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.8692, \"times_seen\": 9.0}, {\"site\": 495, \"mutant\": \"Y\", \"escape\": -0.011333289390790853, \"epitope\": \"epitope 1\", \"reference_site\": \"498\", \"functional effect\": -0.0976, \"times_seen\": 7.0}, {\"site\": 496, \"mutant\": \"-\", \"escape\": 0.18240698700748115, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 496, \"mutant\": \"H\", \"escape\": 4.576261408279544, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.4608, \"times_seen\": 4.0}, {\"site\": 496, \"mutant\": \"L\", \"escape\": 0.34078996977433346, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -1.8239, \"times_seen\": 3.0}, {\"site\": 496, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 496, \"mutant\": \"Q\", \"escape\": 4.472294207911231, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.5042, \"times_seen\": 2.0}, {\"site\": 496, \"mutant\": \"R\", \"escape\": 2.4678402802123296, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -2.0994, \"times_seen\": 6.0}, {\"site\": 496, \"mutant\": \"S\", \"escape\": 6.198218940121732, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.0307, \"times_seen\": 10.0}, {\"site\": 496, \"mutant\": \"T\", \"escape\": 6.012134126166502, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -0.3631, \"times_seen\": 3.0}, {\"site\": 496, \"mutant\": \"V\", \"escape\": 5.297277305561363, \"epitope\": \"epitope 1\", \"reference_site\": \"499\", \"functional effect\": -2.3457, \"times_seen\": 2.0}, {\"site\": 497, \"mutant\": \"-\", \"escape\": 0.06430000668432193, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 497, \"mutant\": \"A\", \"escape\": 3.8959062104006743, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": -0.5078, \"times_seen\": 13.0}, {\"site\": 497, \"mutant\": \"I\", \"escape\": 0.030889194855731796, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": -1.0395, \"times_seen\": 5.0}, {\"site\": 497, \"mutant\": \"N\", \"escape\": 1.3230341737188476, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": 0.2023, \"times_seen\": 4.0}, {\"site\": 497, \"mutant\": \"S\", \"escape\": 2.6117288615914505, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": 0.006, \"times_seen\": 13.0}, {\"site\": 497, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"500\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 498, \"mutant\": \"*\", \"escape\": 0.016472819671924176, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.8664, \"times_seen\": 3.0}, {\"site\": 498, \"mutant\": \"A\", \"escape\": 0.05224537880200472, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1028, \"times_seen\": 31.0}, {\"site\": 498, \"mutant\": \"C\", \"escape\": -0.005819193617188566, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 498, \"mutant\": \"D\", \"escape\": -0.02575626386886746, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1304, \"times_seen\": 9.0}, {\"site\": 498, \"mutant\": \"E\", \"escape\": -0.14443758700956344, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0618, \"times_seen\": 26.0}, {\"site\": 498, \"mutant\": \"F\", \"escape\": -0.038510673176396004, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.0232, \"times_seen\": 28.0}, {\"site\": 498, \"mutant\": \"G\", \"escape\": -0.0621382810529851, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0356, \"times_seen\": 17.0}, {\"site\": 498, \"mutant\": \"H\", \"escape\": -0.05030271034239594, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0028, \"times_seen\": 26.0}, {\"site\": 498, \"mutant\": \"I\", \"escape\": 1.3533380682065361, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.3911, \"times_seen\": 48.0}, {\"site\": 498, \"mutant\": \"K\", \"escape\": 0.011833656083857565, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.849, \"times_seen\": 3.0}, {\"site\": 498, \"mutant\": \"L\", \"escape\": 0.039498463209418286, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1459, \"times_seen\": 48.0}, {\"site\": 498, \"mutant\": \"M\", \"escape\": 0.011030545765550305, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.1332, \"times_seen\": 14.0}, {\"site\": 498, \"mutant\": \"N\", \"escape\": -0.30435170380783755, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0985, \"times_seen\": 64.0}, {\"site\": 498, \"mutant\": \"P\", \"escape\": 0.009282253585195303, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.004, \"times_seen\": 8.0}, {\"site\": 498, \"mutant\": \"Q\", \"escape\": -0.23890881702458763, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.1512, \"times_seen\": 11.0}, {\"site\": 498, \"mutant\": \"R\", \"escape\": -0.01393094749901353, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -2.9894, \"times_seen\": 7.0}, {\"site\": 498, \"mutant\": \"S\", \"escape\": -0.14804427728164044, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0133, \"times_seen\": 73.0}, {\"site\": 498, \"mutant\": \"T\", \"escape\": -0.2880544313827705, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.047, \"times_seen\": 50.0}, {\"site\": 498, \"mutant\": \"V\", \"escape\": 0.03732399453316264, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.0001, \"times_seen\": 47.0}, {\"site\": 498, \"mutant\": \"W\", \"escape\": 1.809955665121597, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": -0.376, \"times_seen\": 27.0}, {\"site\": 498, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"501\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 499, \"mutant\": \"*\", \"escape\": -0.0005376634730347668, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -3.0563, \"times_seen\": 1.0}, {\"site\": 499, \"mutant\": \"E\", \"escape\": -0.011037190040682342, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -2.6212, \"times_seen\": 1.0}, {\"site\": 499, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 499, \"mutant\": \"R\", \"escape\": 0.03902285076682938, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -2.936, \"times_seen\": 2.0}, {\"site\": 499, \"mutant\": \"S\", \"escape\": -0.029370317963980926, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -0.1043, \"times_seen\": 7.0}, {\"site\": 499, \"mutant\": \"V\", \"escape\": 0.018393532742852686, \"epitope\": \"epitope 1\", \"reference_site\": \"502\", \"functional effect\": -2.1212, \"times_seen\": 1.0}, {\"site\": 500, \"mutant\": \"A\", \"escape\": -0.002247538207779511, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.0538, \"times_seen\": 10.0}, {\"site\": 500, \"mutant\": \"E\", \"escape\": -0.0036416307071724606, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.3375, \"times_seen\": 1.0}, {\"site\": 500, \"mutant\": \"F\", \"escape\": -0.037226663439683734, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.1554, \"times_seen\": 12.0}, {\"site\": 500, \"mutant\": \"G\", \"escape\": -0.007568598155471689, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.7935, \"times_seen\": 8.0}, {\"site\": 500, \"mutant\": \"I\", \"escape\": 0.00700630932338501, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.1889, \"times_seen\": 10.0}, {\"site\": 500, \"mutant\": \"L\", \"escape\": 0.004882863070789613, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.1482, \"times_seen\": 16.0}, {\"site\": 500, \"mutant\": \"M\", \"escape\": -0.01699580185733167, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": -0.1088, \"times_seen\": 8.0}, {\"site\": 500, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"503\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 501, \"mutant\": \"C\", \"escape\": 0.024539841032380487, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -2.5791, \"times_seen\": 1.0}, {\"site\": 501, \"mutant\": \"D\", \"escape\": -0.33641677912889273, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.2888, \"times_seen\": 82.0}, {\"site\": 501, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 501, \"mutant\": \"N\", \"escape\": 1.438611251602926, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.2675, \"times_seen\": 5.0}, {\"site\": 501, \"mutant\": \"R\", \"escape\": 0.04316406198709468, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.7602, \"times_seen\": 2.0}, {\"site\": 501, \"mutant\": \"S\", \"escape\": -0.03477993707286321, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.1053, \"times_seen\": 34.0}, {\"site\": 501, \"mutant\": \"V\", \"escape\": 0.0023688553932066344, \"epitope\": \"epitope 1\", \"reference_site\": \"504\", \"functional effect\": -0.6904, \"times_seen\": 12.0}, {\"site\": 502, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 502, \"mutant\": \"A\", \"escape\": 0.5847516768303384, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.0962, \"times_seen\": 17.0}, {\"site\": 502, \"mutant\": \"C\", \"escape\": -0.0056257416939123174, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -2.6374, \"times_seen\": 3.0}, {\"site\": 502, \"mutant\": \"D\", \"escape\": -0.18378079383785462, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.2021, \"times_seen\": 20.0}, {\"site\": 502, \"mutant\": \"E\", \"escape\": -0.004158892011964045, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.1255, \"times_seen\": 4.0}, {\"site\": 502, \"mutant\": \"F\", \"escape\": -2.9177287623929375, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1583, \"times_seen\": 17.0}, {\"site\": 502, \"mutant\": \"G\", \"escape\": -0.06564980173564289, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.7695, \"times_seen\": 9.0}, {\"site\": 502, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 502, \"mutant\": \"I\", \"escape\": -0.0056709850109106594, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.8906, \"times_seen\": 1.0}, {\"site\": 502, \"mutant\": \"K\", \"escape\": -0.024751793347415504, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.9618, \"times_seen\": 6.0}, {\"site\": 502, \"mutant\": \"L\", \"escape\": -0.0823298757799275, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.0845, \"times_seen\": 39.0}, {\"site\": 502, \"mutant\": \"M\", \"escape\": -0.03230680675431812, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": 0.2724, \"times_seen\": 6.0}, {\"site\": 502, \"mutant\": \"N\", \"escape\": -0.05266484255668215, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1694, \"times_seen\": 24.0}, {\"site\": 502, \"mutant\": \"P\", \"escape\": -0.00217843340984705, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -2.9748, \"times_seen\": 11.0}, {\"site\": 502, \"mutant\": \"Q\", \"escape\": -0.05903382156467558, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.0357, \"times_seen\": 27.0}, {\"site\": 502, \"mutant\": \"R\", \"escape\": -0.16500371427516708, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.0928, \"times_seen\": 58.0}, {\"site\": 502, \"mutant\": \"S\", \"escape\": -0.04705304887393154, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.3556, \"times_seen\": 23.0}, {\"site\": 502, \"mutant\": \"T\", \"escape\": -0.0447908488901209, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.0339, \"times_seen\": 10.0}, {\"site\": 502, \"mutant\": \"V\", \"escape\": -0.021498490191442576, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -1.2803, \"times_seen\": 6.0}, {\"site\": 502, \"mutant\": \"W\", \"escape\": -0.0031084686040624707, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1674, \"times_seen\": 7.0}, {\"site\": 502, \"mutant\": \"Y\", \"escape\": -0.42649609140598066, \"epitope\": \"epitope 1\", \"reference_site\": \"505\", \"functional effect\": -0.1237, \"times_seen\": 40.0}, {\"site\": 503, \"mutant\": \"*\", \"escape\": -0.00034536598052111616, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -3.1158, \"times_seen\": 1.0}, {\"site\": 503, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -2.1871, \"times_seen\": null}, {\"site\": 503, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -2.8228, \"times_seen\": null}, {\"site\": 503, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 503, \"mutant\": \"R\", \"escape\": -0.0011596719736511425, \"epitope\": \"epitope 1\", \"reference_site\": \"506\", \"functional effect\": -2.8214, \"times_seen\": 1.0}, {\"site\": 504, \"mutant\": \"A\", \"escape\": -0.00614717484737508, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -1.0223, \"times_seen\": 3.0}, {\"site\": 504, \"mutant\": \"L\", \"escape\": -0.0023470322295662976, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -2.8046, \"times_seen\": 1.0}, {\"site\": 504, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 504, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 504, \"mutant\": \"S\", \"escape\": 0.026956209211135056, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -2.3546, \"times_seen\": 2.0}, {\"site\": 504, \"mutant\": \"T\", \"escape\": -0.0017559992655976988, \"epitope\": \"epitope 1\", \"reference_site\": \"507\", \"functional effect\": -1.6578, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"*\", \"escape\": -0.006109332849209254, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -1.0566, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 505, \"mutant\": \"C\", \"escape\": -0.02704330741996962, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -0.9961, \"times_seen\": 5.0}, {\"site\": 505, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": -2.3822, \"times_seen\": null}, {\"site\": 505, \"mutant\": \"F\", \"escape\": -0.003454051317681077, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.0169, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"H\", \"escape\": 0.0069789809876143905, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.1304, \"times_seen\": 11.0}, {\"site\": 505, \"mutant\": \"N\", \"escape\": -0.0032545783116434347, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"508\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 506, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 506, \"mutant\": \"G\", \"escape\": -0.008902417863610648, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.951, \"times_seen\": 1.0}, {\"site\": 506, \"mutant\": \"K\", \"escape\": 0.03145118277779276, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -1.815, \"times_seen\": 2.0}, {\"site\": 506, \"mutant\": \"M\", \"escape\": -0.0006430927843209962, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.8316, \"times_seen\": 1.0}, {\"site\": 506, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 506, \"mutant\": \"S\", \"escape\": -0.002977636531819933, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -2.9775, \"times_seen\": 1.0}, {\"site\": 506, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"509\", \"functional effect\": -3.2089, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.4638, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.8298, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"I\", \"escape\": -0.01768693118315265, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -0.8584, \"times_seen\": 4.0}, {\"site\": 507, \"mutant\": \"L\", \"escape\": -0.05426749207138435, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -2.6987, \"times_seen\": 5.0}, {\"site\": 507, \"mutant\": \"M\", \"escape\": -0.004229549694190818, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": -1.5842, \"times_seen\": 1.0}, {\"site\": 507, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"510\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 508, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 508, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -3.0986, \"times_seen\": null}, {\"site\": 508, \"mutant\": \"I\", \"escape\": 0.01828434087714316, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -1.2286, \"times_seen\": 3.0}, {\"site\": 508, \"mutant\": \"L\", \"escape\": 0.02160993460978853, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -1.83, \"times_seen\": 2.0}, {\"site\": 508, \"mutant\": \"M\", \"escape\": -0.0024811887588884374, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": -1.3902, \"times_seen\": 7.0}, {\"site\": 508, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"511\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.7182, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.9858, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"I\", \"escape\": -0.007810980371387118, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -1.3994, \"times_seen\": 4.0}, {\"site\": 509, \"mutant\": \"L\", \"escape\": -0.003199058851464656, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.8254, \"times_seen\": 1.0}, {\"site\": 509, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": -2.8415, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"512\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"F\", \"escape\": -0.029573354552523447, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -0.3652, \"times_seen\": 11.0}, {\"site\": 510, \"mutant\": \"I\", \"escape\": -0.0064689436259496216, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -1.4701, \"times_seen\": 2.0}, {\"site\": 510, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"M\", \"escape\": -0.01826521682022529, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -0.38, \"times_seen\": 9.0}, {\"site\": 510, \"mutant\": \"P\", \"escape\": -0.01133640484598958, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.8942, \"times_seen\": 5.0}, {\"site\": 510, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.8948, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"R\", \"escape\": -0.0036069864545612202, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -0.8287, \"times_seen\": 1.0}, {\"site\": 510, \"mutant\": \"T\", \"escape\": -0.003467115123619186, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -2.4129, \"times_seen\": 1.0}, {\"site\": 510, \"mutant\": \"V\", \"escape\": -0.024680243287869878, \"epitope\": \"epitope 1\", \"reference_site\": \"513\", \"functional effect\": -1.5414, \"times_seen\": 4.0}, {\"site\": 511, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -3.1416, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"C\", \"escape\": -0.004044505562846324, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -0.8028, \"times_seen\": 1.0}, {\"site\": 511, \"mutant\": \"F\", \"escape\": -0.04179197193774355, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -1.7083, \"times_seen\": 15.0}, {\"site\": 511, \"mutant\": \"N\", \"escape\": 0.01531461706204512, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": 0.0622, \"times_seen\": 10.0}, {\"site\": 511, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -2.608, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"T\", \"escape\": -0.02389366971690866, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -0.1658, \"times_seen\": 24.0}, {\"site\": 511, \"mutant\": \"Y\", \"escape\": -0.03594847977973879, \"epitope\": \"epitope 1\", \"reference_site\": \"514\", \"functional effect\": -1.2422, \"times_seen\": 23.0}, {\"site\": 512, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.9644, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -3.2839, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"L\", \"escape\": -0.004521827860740644, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -0.3377, \"times_seen\": 12.0}, {\"site\": 512, \"mutant\": \"S\", \"escape\": 0.007795834384709985, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.6288, \"times_seen\": 5.0}, {\"site\": 512, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.6904, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"515\", \"functional effect\": -2.3583, \"times_seen\": null}, {\"site\": 513, \"mutant\": \"*\", \"escape\": 0.016576137845475798, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -1.7671, \"times_seen\": 1.0}, {\"site\": 513, \"mutant\": \"A\", \"escape\": 2.6461894879527606e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.8865, \"times_seen\": 1.0}, {\"site\": 513, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 513, \"mutant\": \"G\", \"escape\": -0.024808048467886878, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.6653, \"times_seen\": 5.0}, {\"site\": 513, \"mutant\": \"K\", \"escape\": -0.009467252246845173, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -1.2325, \"times_seen\": 26.0}, {\"site\": 513, \"mutant\": \"Q\", \"escape\": 0.006956549274444214, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.1296, \"times_seen\": 20.0}, {\"site\": 513, \"mutant\": \"S\", \"escape\": -0.0021828502969355613, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.5221, \"times_seen\": 3.0}, {\"site\": 513, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"516\", \"functional effect\": -0.8143, \"times_seen\": null}, {\"site\": 514, \"mutant\": \"F\", \"escape\": -0.01917922104076742, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": 0.1757, \"times_seen\": 29.0}, {\"site\": 514, \"mutant\": \"H\", \"escape\": -0.008568270775146422, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.6957, \"times_seen\": 12.0}, {\"site\": 514, \"mutant\": \"I\", \"escape\": 0.0735807133080542, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": 0.1283, \"times_seen\": 32.0}, {\"site\": 514, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 514, \"mutant\": \"M\", \"escape\": -0.005071470879849978, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.1504, \"times_seen\": 3.0}, {\"site\": 514, \"mutant\": \"P\", \"escape\": 1.6470729417452723, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -1.4089, \"times_seen\": 2.0}, {\"site\": 514, \"mutant\": \"Q\", \"escape\": 0.018205445481475215, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -1.2135, \"times_seen\": 2.0}, {\"site\": 514, \"mutant\": \"R\", \"escape\": -0.0029490939952039794, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -2.1178, \"times_seen\": 5.0}, {\"site\": 514, \"mutant\": \"T\", \"escape\": -0.020440515203819388, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.8606, \"times_seen\": 8.0}, {\"site\": 514, \"mutant\": \"V\", \"escape\": -0.04773962562806976, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.0136, \"times_seen\": 66.0}, {\"site\": 514, \"mutant\": \"Y\", \"escape\": -0.008932449559677692, \"epitope\": \"epitope 1\", \"reference_site\": \"517\", \"functional effect\": -0.9741, \"times_seen\": 7.0}, {\"site\": 515, \"mutant\": \"F\", \"escape\": -0.05841809265064975, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.19, \"times_seen\": 20.0}, {\"site\": 515, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.5171, \"times_seen\": null}, {\"site\": 515, \"mutant\": \"I\", \"escape\": -0.020669476017235722, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.1959, \"times_seen\": 22.0}, {\"site\": 515, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 515, \"mutant\": \"M\", \"escape\": -0.007236369998546122, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.124, \"times_seen\": 7.0}, {\"site\": 515, \"mutant\": \"P\", \"escape\": -0.027966916795990077, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.3749, \"times_seen\": 14.0}, {\"site\": 515, \"mutant\": \"Q\", \"escape\": -0.008653891274163486, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": -0.5652, \"times_seen\": 10.0}, {\"site\": 515, \"mutant\": \"V\", \"escape\": 0.00524910731744975, \"epitope\": \"epitope 1\", \"reference_site\": \"518\", \"functional effect\": 0.0737, \"times_seen\": 5.0}, {\"site\": 516, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -1.0538, \"times_seen\": null}, {\"site\": 516, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 516, \"mutant\": \"L\", \"escape\": -0.04708595187383352, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.6861, \"times_seen\": 35.0}, {\"site\": 516, \"mutant\": \"N\", \"escape\": 0.043938242838191775, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.7408, \"times_seen\": 21.0}, {\"site\": 516, \"mutant\": \"P\", \"escape\": -0.03294126608246012, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.1239, \"times_seen\": 21.0}, {\"site\": 516, \"mutant\": \"Q\", \"escape\": -0.057448531111485845, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.0534, \"times_seen\": 14.0}, {\"site\": 516, \"mutant\": \"R\", \"escape\": -0.02178070039587555, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -1.268, \"times_seen\": 9.0}, {\"site\": 516, \"mutant\": \"V\", \"escape\": 0.01680414520409566, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": -0.6903, \"times_seen\": 1.0}, {\"site\": 516, \"mutant\": \"Y\", \"escape\": -0.016326655463338176, \"epitope\": \"epitope 1\", \"reference_site\": \"519\", \"functional effect\": 0.0498, \"times_seen\": 34.0}, {\"site\": 517, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 517, \"mutant\": \"D\", \"escape\": 0.004623887540879804, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -0.6494, \"times_seen\": 4.0}, {\"site\": 517, \"mutant\": \"E\", \"escape\": 0.0074783957162037, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -0.226, \"times_seen\": 9.0}, {\"site\": 517, \"mutant\": \"G\", \"escape\": -0.6351399370004586, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 517, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -2.0683, \"times_seen\": null}, {\"site\": 517, \"mutant\": \"P\", \"escape\": -0.022019026753356992, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -1.6363, \"times_seen\": 9.0}, {\"site\": 517, \"mutant\": \"S\", \"escape\": -0.06530313871717819, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -0.13, \"times_seen\": 60.0}, {\"site\": 517, \"mutant\": \"T\", \"escape\": 0.2714070914332029, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -1.255, \"times_seen\": 30.0}, {\"site\": 517, \"mutant\": \"V\", \"escape\": -0.006636303574404506, \"epitope\": \"epitope 1\", \"reference_site\": \"520\", \"functional effect\": -1.6988, \"times_seen\": 20.0}, {\"site\": 518, \"mutant\": \"A\", \"escape\": -0.0018051934256020077, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -1.0538, \"times_seen\": 1.0}, {\"site\": 518, \"mutant\": \"H\", \"escape\": -0.00032796839634752234, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.0597, \"times_seen\": 2.0}, {\"site\": 518, \"mutant\": \"L\", \"escape\": 0.02479855936426647, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -1.6256, \"times_seen\": 13.0}, {\"site\": 518, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 518, \"mutant\": \"Q\", \"escape\": 0.0376049541739587, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.2545, \"times_seen\": 18.0}, {\"site\": 518, \"mutant\": \"R\", \"escape\": -0.04518040301336764, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 518, \"mutant\": \"S\", \"escape\": 0.018614795524638055, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.4019, \"times_seen\": 17.0}, {\"site\": 518, \"mutant\": \"T\", \"escape\": -0.041635901657327175, \"epitope\": \"epitope 1\", \"reference_site\": \"521\", \"functional effect\": -0.3776, \"times_seen\": 22.0}, {\"site\": 519, \"mutant\": \"*\", \"escape\": -0.003502295778088055, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.9549, \"times_seen\": 1.0}, {\"site\": 519, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.36, \"times_seen\": null}, {\"site\": 519, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 519, \"mutant\": \"C\", \"escape\": -0.0192952433119132, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.781, \"times_seen\": 25.0}, {\"site\": 519, \"mutant\": \"D\", \"escape\": 0.1202718419966804, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3558, \"times_seen\": 33.0}, {\"site\": 519, \"mutant\": \"E\", \"escape\": -0.02847061834291918, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3925, \"times_seen\": 15.0}, {\"site\": 519, \"mutant\": \"F\", \"escape\": -0.012923921554158096, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.6136, \"times_seen\": 27.0}, {\"site\": 519, \"mutant\": \"G\", \"escape\": 0.06217708590506621, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.8527, \"times_seen\": 45.0}, {\"site\": 519, \"mutant\": \"H\", \"escape\": -0.01380131992597817, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3548, \"times_seen\": 5.0}, {\"site\": 519, \"mutant\": \"I\", \"escape\": -0.0005060235298682619, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.092, \"times_seen\": 12.0}, {\"site\": 519, \"mutant\": \"K\", \"escape\": -0.0037904127636202247, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -2.5438, \"times_seen\": 1.0}, {\"site\": 519, \"mutant\": \"L\", \"escape\": -0.03099522804042058, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.747, \"times_seen\": 34.0}, {\"site\": 519, \"mutant\": \"M\", \"escape\": 0.026667884324591263, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.3471, \"times_seen\": 9.0}, {\"site\": 519, \"mutant\": \"N\", \"escape\": -0.035056901962924276, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.8793, \"times_seen\": 6.0}, {\"site\": 519, \"mutant\": \"P\", \"escape\": 0.054409996046261455, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": 0.1483, \"times_seen\": 44.0}, {\"site\": 519, \"mutant\": \"Q\", \"escape\": -0.009343889894690757, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.8429, \"times_seen\": 3.0}, {\"site\": 519, \"mutant\": \"R\", \"escape\": -0.03281551238915841, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -2.3261, \"times_seen\": 17.0}, {\"site\": 519, \"mutant\": \"S\", \"escape\": -0.014608137556499437, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.2522, \"times_seen\": 76.0}, {\"site\": 519, \"mutant\": \"T\", \"escape\": -0.05255656780361712, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.2783, \"times_seen\": 67.0}, {\"site\": 519, \"mutant\": \"V\", \"escape\": -0.4888468559591391, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -0.2323, \"times_seen\": 116.0}, {\"site\": 519, \"mutant\": \"W\", \"escape\": -0.008741084651178907, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": -1.3283, \"times_seen\": 3.0}, {\"site\": 519, \"mutant\": \"Y\", \"escape\": -0.039508972758052124, \"epitope\": \"epitope 1\", \"reference_site\": \"522\", \"functional effect\": 0.0691, \"times_seen\": 15.0}, {\"site\": 520, \"mutant\": \"A\", \"escape\": -0.16050880307649754, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -0.4663, \"times_seen\": 46.0}, {\"site\": 520, \"mutant\": \"I\", \"escape\": -0.021907126672973638, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -1.99, \"times_seen\": 17.0}, {\"site\": 520, \"mutant\": \"K\", \"escape\": -0.003652250278142818, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -2.2485, \"times_seen\": 1.0}, {\"site\": 520, \"mutant\": \"N\", \"escape\": 0.13884831367311914, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -0.7974, \"times_seen\": 28.0}, {\"site\": 520, \"mutant\": \"P\", \"escape\": -0.003706765571991875, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 520, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": -2.1929, \"times_seen\": null}, {\"site\": 520, \"mutant\": \"S\", \"escape\": -0.041549575551335094, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": 0.2301, \"times_seen\": 14.0}, {\"site\": 520, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"523\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -3.2398, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"C\", \"escape\": -0.003403023308125182, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 521, \"mutant\": \"E\", \"escape\": -0.003752692606712385, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -2.1667, \"times_seen\": 1.0}, {\"site\": 521, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -0.1108, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -2.3718, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -0.9578, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -2.8275, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": -3.0875, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"524\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -2.9129, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -2.9482, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -1.8801, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"W\", \"escape\": -0.0032303199794277517, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -0.9191, \"times_seen\": 1.0}, {\"site\": 522, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"525\", \"functional effect\": -3.1198, \"times_seen\": null}, {\"site\": 523, \"mutant\": \"*\", \"escape\": -0.002837407398288519, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -2.1818, \"times_seen\": 1.0}, {\"site\": 523, \"mutant\": \"A\", \"escape\": -0.0029845401220086032, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -0.6305, \"times_seen\": 2.0}, {\"site\": 523, \"mutant\": \"E\", \"escape\": -0.001880303459420257, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -1.0706, \"times_seen\": 2.0}, {\"site\": 523, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 523, \"mutant\": \"P\", \"escape\": -0.00852172969019343, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -0.6872, \"times_seen\": 3.0}, {\"site\": 523, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -2.4069, \"times_seen\": null}, {\"site\": 523, \"mutant\": \"V\", \"escape\": -0.0032403061596312475, \"epitope\": \"epitope 1\", \"reference_site\": \"526\", \"functional effect\": -2.7353, \"times_seen\": 1.0}, {\"site\": 524, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -2.6649, \"times_seen\": null}, {\"site\": 524, \"mutant\": \"K\", \"escape\": -0.011866332336451308, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -0.785, \"times_seen\": 2.0}, {\"site\": 524, \"mutant\": \"L\", \"escape\": -0.7923319878231738, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -2.6974, \"times_seen\": 2.0}, {\"site\": 524, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 524, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -2.5665, \"times_seen\": null}, {\"site\": 524, \"mutant\": \"S\", \"escape\": -0.02317890803118984, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -1.9063, \"times_seen\": 5.0}, {\"site\": 524, \"mutant\": \"T\", \"escape\": 0.004344763476033843, \"epitope\": \"epitope 1\", \"reference_site\": \"527\", \"functional effect\": -1.7467, \"times_seen\": 3.0}, {\"site\": 525, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"E\", \"escape\": -0.051884403958108824, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.5715, \"times_seen\": 16.0}, {\"site\": 525, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.7343, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"I\", \"escape\": -0.03710904764207008, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": 0.0142, \"times_seen\": 16.0}, {\"site\": 525, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"N\", \"escape\": -0.004132935833577881, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -2.2802, \"times_seen\": 1.0}, {\"site\": 525, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -2.9407, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"Q\", \"escape\": -0.030539704100880697, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.0454, \"times_seen\": 10.0}, {\"site\": 525, \"mutant\": \"R\", \"escape\": -0.01882883505413817, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.3537, \"times_seen\": 5.0}, {\"site\": 525, \"mutant\": \"T\", \"escape\": -0.0076903276197645585, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.0315, \"times_seen\": 2.0}, {\"site\": 525, \"mutant\": \"W\", \"escape\": -0.011530780746222605, \"epitope\": \"epitope 1\", \"reference_site\": \"528\", \"functional effect\": -0.7099, \"times_seen\": 4.0}, {\"site\": 526, \"mutant\": \"E\", \"escape\": -0.03511302660536883, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.2878, \"times_seen\": 11.0}, {\"site\": 526, \"mutant\": \"G\", \"escape\": -0.004875797243377748, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.6437, \"times_seen\": 2.0}, {\"site\": 526, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 526, \"mutant\": \"L\", \"escape\": -0.00495615473671819, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.2172, \"times_seen\": 5.0}, {\"site\": 526, \"mutant\": \"M\", \"escape\": -0.029013649511320436, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.3064, \"times_seen\": 11.0}, {\"site\": 526, \"mutant\": \"N\", \"escape\": -0.00046601422456279035, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.3323, \"times_seen\": 17.0}, {\"site\": 526, \"mutant\": \"Q\", \"escape\": 0.004907676710168152, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.2839, \"times_seen\": 11.0}, {\"site\": 526, \"mutant\": \"R\", \"escape\": 0.5397633302650565, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.3896, \"times_seen\": 37.0}, {\"site\": 526, \"mutant\": \"T\", \"escape\": -0.007956970590830902, \"epitope\": \"epitope 1\", \"reference_site\": \"529\", \"functional effect\": -0.0142, \"times_seen\": 7.0}, {\"site\": 527, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -3.261, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"G\", \"escape\": -0.014786536948352868, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -1.2372, \"times_seen\": 4.0}, {\"site\": 527, \"mutant\": \"I\", \"escape\": -0.00711215001246186, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -0.6498, \"times_seen\": 2.0}, {\"site\": 527, \"mutant\": \"N\", \"escape\": -0.08237276313704829, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -1.1321, \"times_seen\": 21.0}, {\"site\": 527, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -2.6451, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"V\", \"escape\": -0.011850159219998492, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -0.5927, \"times_seen\": 6.0}, {\"site\": 527, \"mutant\": \"W\", \"escape\": -0.004297269797628714, \"epitope\": \"epitope 1\", \"reference_site\": \"530\", \"functional effect\": -2.5076, \"times_seen\": 1.0}, {\"site\": 528, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -2.6907, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"G\", \"escape\": 0.015841478241794365, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -2.6095, \"times_seen\": 2.0}, {\"site\": 528, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -3.0131, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"L\", \"escape\": 0.020063531906484557, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -2.8056, \"times_seen\": 1.0}, {\"site\": 528, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -1.7137, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": -1.218, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"531\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 529, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 529, \"mutant\": \"D\", \"escape\": 0.0005465856155019809, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.1006, \"times_seen\": 10.0}, {\"site\": 529, \"mutant\": \"H\", \"escape\": 0.010300337704574466, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.1214, \"times_seen\": 3.0}, {\"site\": 529, \"mutant\": \"I\", \"escape\": 0.01112979615745436, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -1.0965, \"times_seen\": 6.0}, {\"site\": 529, \"mutant\": \"K\", \"escape\": -0.007846412446408728, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.0009, \"times_seen\": 11.0}, {\"site\": 529, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 529, \"mutant\": \"P\", \"escape\": 0.053195280715518926, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 529, \"mutant\": \"S\", \"escape\": -0.02719366735994338, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.0208, \"times_seen\": 22.0}, {\"site\": 529, \"mutant\": \"V\", \"escape\": -0.0016562737269386, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.3049, \"times_seen\": 1.0}, {\"site\": 529, \"mutant\": \"Y\", \"escape\": -0.014688625147353772, \"epitope\": \"epitope 1\", \"reference_site\": \"532\", \"functional effect\": -0.1035, \"times_seen\": 5.0}, {\"site\": 530, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"F\", \"escape\": -0.004496217661419621, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -2.0848, \"times_seen\": 2.0}, {\"site\": 530, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"M\", \"escape\": 0.04465636749340869, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -1.0553, \"times_seen\": 6.0}, {\"site\": 530, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -2.1012, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -3.1267, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -3.2559, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -2.5095, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"V\", \"escape\": 0.042848306182469285, \"epitope\": \"epitope 1\", \"reference_site\": \"533\", \"functional effect\": -1.1578, \"times_seen\": 7.0}, {\"site\": 531, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 531, \"mutant\": \"A\", \"escape\": 0.0275669407930567, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -1.5204, \"times_seen\": 9.0}, {\"site\": 531, \"mutant\": \"F\", \"escape\": -0.015661307861243548, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -2.7729, \"times_seen\": 6.0}, {\"site\": 531, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -1.9197, \"times_seen\": null}, {\"site\": 531, \"mutant\": \"I\", \"escape\": -0.038812145290377395, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -0.0695, \"times_seen\": 28.0}, {\"site\": 531, \"mutant\": \"L\", \"escape\": -0.01726097221199365, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -0.7782, \"times_seen\": 8.0}, {\"site\": 531, \"mutant\": \"M\", \"escape\": -0.011110017259067784, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -1.2792, \"times_seen\": 5.0}, {\"site\": 531, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": -2.5316, \"times_seen\": null}, {\"site\": 531, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"534\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"E\", \"escape\": -0.002748245730647302, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -1.3257, \"times_seen\": 1.0}, {\"site\": 532, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -1.7736, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -2.633, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"R\", \"escape\": -0.026959070549715716, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -0.6013, \"times_seen\": 12.0}, {\"site\": 532, \"mutant\": \"T\", \"escape\": 0.05224744450263728, \"epitope\": \"epitope 1\", \"reference_site\": \"535\", \"functional effect\": -0.4288, \"times_seen\": 6.0}, {\"site\": 533, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 533, \"mutant\": \"D\", \"escape\": -0.05125553007900755, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.1753, \"times_seen\": 17.0}, {\"site\": 533, \"mutant\": \"K\", \"escape\": -0.06621372947774307, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.5918, \"times_seen\": 18.0}, {\"site\": 533, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 533, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -3.0933, \"times_seen\": null}, {\"site\": 533, \"mutant\": \"Q\", \"escape\": -0.010147410474319727, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -1.124, \"times_seen\": 3.0}, {\"site\": 533, \"mutant\": \"S\", \"escape\": -0.03564203695464222, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.7847, \"times_seen\": 8.0}, {\"site\": 533, \"mutant\": \"W\", \"escape\": -0.002626623192529412, \"epitope\": \"epitope 1\", \"reference_site\": \"536\", \"functional effect\": -0.9078, \"times_seen\": 1.0}, {\"site\": 534, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -2.101, \"times_seen\": null}, {\"site\": 534, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 534, \"mutant\": \"E\", \"escape\": -0.0161547759819037, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.9206, \"times_seen\": 5.0}, {\"site\": 534, \"mutant\": \"G\", \"escape\": -0.021809215405203728, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -2.6262, \"times_seen\": 1.0}, {\"site\": 534, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 534, \"mutant\": \"M\", \"escape\": -0.009376452990934894, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -1.5978, \"times_seen\": 5.0}, {\"site\": 534, \"mutant\": \"N\", \"escape\": 0.00023652512714913819, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -2.6023, \"times_seen\": 5.0}, {\"site\": 534, \"mutant\": \"Q\", \"escape\": -0.003096508127864746, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.5799, \"times_seen\": 2.0}, {\"site\": 534, \"mutant\": \"R\", \"escape\": -0.008838848751006247, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.2885, \"times_seen\": 3.0}, {\"site\": 534, \"mutant\": \"T\", \"escape\": -0.002590527637889781, \"epitope\": \"epitope 1\", \"reference_site\": \"537\", \"functional effect\": -0.2944, \"times_seen\": 3.0}, {\"site\": 535, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.9372, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"F\", \"escape\": -0.0032132165689040394, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.9432, \"times_seen\": 1.0}, {\"site\": 535, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -3.0562, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.9066, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -3.233, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.4097, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"Y\", \"escape\": -0.0031475411337903996, \"epitope\": \"epitope 1\", \"reference_site\": \"538\", \"functional effect\": -2.6424, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"A\", \"escape\": -0.003469902911265562, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -2.5994, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"C\", \"escape\": -0.0039446283570067405, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -2.9985, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 536, \"mutant\": \"I\", \"escape\": -0.020647255721664617, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -0.192, \"times_seen\": 11.0}, {\"site\": 536, \"mutant\": \"L\", \"escape\": -0.0033111558861113545, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -1.9369, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": -2.809, \"times_seen\": null}, {\"site\": 536, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"539\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 537, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 537, \"mutant\": \"D\", \"escape\": 9.37907751465504e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.2562, \"times_seen\": 16.0}, {\"site\": 537, \"mutant\": \"H\", \"escape\": 0.0023829435984717255, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.395, \"times_seen\": 1.0}, {\"site\": 537, \"mutant\": \"I\", \"escape\": -0.0035283464737232207, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -1.0693, \"times_seen\": 1.0}, {\"site\": 537, \"mutant\": \"K\", \"escape\": -0.01222321157176997, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.1286, \"times_seen\": 11.0}, {\"site\": 537, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 537, \"mutant\": \"Q\", \"escape\": 0.02416563901951449, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.6167, \"times_seen\": 7.0}, {\"site\": 537, \"mutant\": \"S\", \"escape\": -0.10737490671861735, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.1715, \"times_seen\": 32.0}, {\"site\": 537, \"mutant\": \"T\", \"escape\": 0.057254132964278615, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.232, \"times_seen\": 10.0}, {\"site\": 537, \"mutant\": \"Y\", \"escape\": -0.02781930272047735, \"epitope\": \"epitope 1\", \"reference_site\": \"540\", \"functional effect\": -0.5861, \"times_seen\": 14.0}, {\"site\": 538, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.7164, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -3.0898, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"L\", \"escape\": 0.02476786594248531, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -3.1258, \"times_seen\": 1.0}, {\"site\": 538, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.6257, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"S\", \"escape\": 1.2573882258445515, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": -2.8348, \"times_seen\": 2.0}, {\"site\": 538, \"mutant\": \"Y\", \"escape\": 0.02408027709571175, \"epitope\": \"epitope 1\", \"reference_site\": \"541\", \"functional effect\": 0.0416, \"times_seen\": 1.0}, {\"site\": 539, \"mutant\": \"D\", \"escape\": 0.036062891516500765, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -0.5205, \"times_seen\": 10.0}, {\"site\": 539, \"mutant\": \"H\", \"escape\": -0.0004448653185412213, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.7926, \"times_seen\": 1.0}, {\"site\": 539, \"mutant\": \"K\", \"escape\": 0.019217178909207617, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.9886, \"times_seen\": 1.0}, {\"site\": 539, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 539, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.4756, \"times_seen\": null}, {\"site\": 539, \"mutant\": \"S\", \"escape\": 0.09465753305621644, \"epitope\": \"epitope 1\", \"reference_site\": \"542\", \"functional effect\": -2.3102, \"times_seen\": 2.0}, {\"site\": 540, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -0.0019, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"L\", \"escape\": -0.016800236812855758, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -1.8554, \"times_seen\": 6.0}, {\"site\": 540, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.6852, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"T\", \"escape\": -0.0009983760878345305, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.9328, \"times_seen\": 1.0}, {\"site\": 540, \"mutant\": \"V\", \"escape\": 0.0010165342176622814, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -0.5522, \"times_seen\": 1.0}, {\"site\": 540, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"543\", \"functional effect\": -2.884, \"times_seen\": null}, {\"site\": 541, \"mutant\": \"D\", \"escape\": 0.028933430543118824, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -0.7887, \"times_seen\": 1.0}, {\"site\": 541, \"mutant\": \"G\", \"escape\": 0.015884165481057352, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -0.1076, \"times_seen\": 2.0}, {\"site\": 541, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 541, \"mutant\": \"K\", \"escape\": -0.013772450811039862, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -2.0814, \"times_seen\": 2.0}, {\"site\": 541, \"mutant\": \"M\", \"escape\": -0.017238400900471473, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.329, \"times_seen\": 8.0}, {\"site\": 541, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 541, \"mutant\": \"S\", \"escape\": -0.046865988289227035, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": 0.3651, \"times_seen\": 10.0}, {\"site\": 541, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"544\", \"functional effect\": -0.4128, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"*\", \"escape\": 0.009874494440045265, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -1.8548, \"times_seen\": 2.0}, {\"site\": 542, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.9755, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.7771, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"R\", \"escape\": -0.0035689505582327673, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.745, \"times_seen\": 1.0}, {\"site\": 542, \"mutant\": \"V\", \"escape\": -0.0025153412968484546, \"epitope\": \"epitope 1\", \"reference_site\": \"545\", \"functional effect\": -2.9644, \"times_seen\": 1.0}, {\"site\": 543, \"mutant\": \"F\", \"escape\": -0.014624606121923019, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 543, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 543, \"mutant\": \"M\", \"escape\": 0.019839916147740527, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": 0.2297, \"times_seen\": 4.0}, {\"site\": 543, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": -2.9377, \"times_seen\": null}, {\"site\": 543, \"mutant\": \"Q\", \"escape\": -0.001480318429012732, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": -0.6673, \"times_seen\": 3.0}, {\"site\": 543, \"mutant\": \"V\", \"escape\": -0.001996881066800326, \"epitope\": \"epitope 1\", \"reference_site\": \"546\", \"functional effect\": -0.3809, \"times_seen\": 5.0}, {\"site\": 544, \"mutant\": \"*\", \"escape\": -0.011487460490867997, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -2.6006, \"times_seen\": 4.0}, {\"site\": 544, \"mutant\": \"A\", \"escape\": -0.05989860062659129, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3784, \"times_seen\": 19.0}, {\"site\": 544, \"mutant\": \"C\", \"escape\": -0.008042540426124178, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.4923, \"times_seen\": 2.0}, {\"site\": 544, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -2.6726, \"times_seen\": null}, {\"site\": 544, \"mutant\": \"E\", \"escape\": -0.02914856512329817, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.4994, \"times_seen\": 26.0}, {\"site\": 544, \"mutant\": \"F\", \"escape\": -0.012121532527938938, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.7061, \"times_seen\": 4.0}, {\"site\": 544, \"mutant\": \"G\", \"escape\": -0.03678520302814074, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.9731, \"times_seen\": 10.0}, {\"site\": 544, \"mutant\": \"H\", \"escape\": -0.1253343803001912, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.5209, \"times_seen\": 11.0}, {\"site\": 544, \"mutant\": \"I\", \"escape\": -0.8266061306829697, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.2457, \"times_seen\": 27.0}, {\"site\": 544, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 544, \"mutant\": \"L\", \"escape\": -0.05981978120926586, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.8051, \"times_seen\": 18.0}, {\"site\": 544, \"mutant\": \"M\", \"escape\": -0.4055427120297414, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3205, \"times_seen\": 18.0}, {\"site\": 544, \"mutant\": \"N\", \"escape\": 0.6486051706222269, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.3329, \"times_seen\": 20.0}, {\"site\": 544, \"mutant\": \"P\", \"escape\": -0.01936435003466259, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -2.1393, \"times_seen\": 6.0}, {\"site\": 544, \"mutant\": \"Q\", \"escape\": -0.02519147852705314, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.1241, \"times_seen\": 10.0}, {\"site\": 544, \"mutant\": \"R\", \"escape\": -0.017614926494448516, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": 0.0268, \"times_seen\": 42.0}, {\"site\": 544, \"mutant\": \"S\", \"escape\": -0.027137445378494874, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3465, \"times_seen\": 18.0}, {\"site\": 544, \"mutant\": \"T\", \"escape\": -0.053858974899940494, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.3819, \"times_seen\": 29.0}, {\"site\": 544, \"mutant\": \"V\", \"escape\": -0.03669916013595515, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -0.4142, \"times_seen\": 13.0}, {\"site\": 544, \"mutant\": \"W\", \"escape\": -0.012511833776769685, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.8383, \"times_seen\": 4.0}, {\"site\": 544, \"mutant\": \"Y\", \"escape\": -0.9102924830605447, \"epitope\": \"epitope 1\", \"reference_site\": \"547\", \"functional effect\": -1.3953, \"times_seen\": 5.0}, {\"site\": 545, \"mutant\": \"A\", \"escape\": -0.013321463040697184, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.5715, \"times_seen\": 4.0}, {\"site\": 545, \"mutant\": \"C\", \"escape\": -0.003951366928827087, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.5343, \"times_seen\": 1.0}, {\"site\": 545, \"mutant\": \"D\", \"escape\": 0.011214030772712491, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.9045, \"times_seen\": 2.0}, {\"site\": 545, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.9917, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.9874, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -3.0095, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"548\", \"functional effect\": -2.7874, \"times_seen\": null}, {\"site\": 546, \"mutant\": \"A\", \"escape\": 0.5456739896969567, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.425, \"times_seen\": 31.0}, {\"site\": 546, \"mutant\": \"I\", \"escape\": -0.05611176991872548, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.1083, \"times_seen\": 43.0}, {\"site\": 546, \"mutant\": \"K\", \"escape\": -0.011596589143319316, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.3882, \"times_seen\": 9.0}, {\"site\": 546, \"mutant\": \"P\", \"escape\": -0.008314546620237683, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -2.7505, \"times_seen\": 2.0}, {\"site\": 546, \"mutant\": \"Q\", \"escape\": -0.02008885863980262, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.6592, \"times_seen\": 10.0}, {\"site\": 546, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -1.0964, \"times_seen\": null}, {\"site\": 546, \"mutant\": \"S\", \"escape\": 0.007942296297028154, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": -0.4187, \"times_seen\": 2.0}, {\"site\": 546, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"549\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 547, \"mutant\": \"*\", \"escape\": 0.017564347162912927, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.8942, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"A\", \"escape\": -0.0024004187986909186, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -0.8664, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"E\", \"escape\": -0.0029693061407898374, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -1.8394, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 547, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 547, \"mutant\": \"R\", \"escape\": -0.0009692285004205211, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.7216, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"V\", \"escape\": 0.0005466860735563616, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.4634, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"550\", \"functional effect\": -2.9819, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -2.9188, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -3.0603, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"F\", \"escape\": -0.007318621407519259, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -1.1944, \"times_seen\": 3.0}, {\"site\": 548, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -2.8877, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"I\", \"escape\": 0.017382034199440666, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -0.3624, \"times_seen\": 8.0}, {\"site\": 548, \"mutant\": \"K\", \"escape\": 0.027267163248298813, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -1.7071, \"times_seen\": 4.0}, {\"site\": 548, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -0.1976, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"M\", \"escape\": -0.008453601600089317, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -0.4589, \"times_seen\": 10.0}, {\"site\": 548, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"W\", \"escape\": 0.0021932628520432555, \"epitope\": \"epitope 1\", \"reference_site\": \"551\", \"functional effect\": -2.2832, \"times_seen\": 3.0}, {\"site\": 549, \"mutant\": \"F\", \"escape\": -0.005900493019768691, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.7077, \"times_seen\": 1.0}, {\"site\": 549, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.9185, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"I\", \"escape\": 0.008304097681294977, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -0.2605, \"times_seen\": 3.0}, {\"site\": 549, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"M\", \"escape\": -0.0158446076226749, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.5107, \"times_seen\": 4.0}, {\"site\": 549, \"mutant\": \"P\", \"escape\": -0.4183974819481201, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -2.3878, \"times_seen\": 4.0}, {\"site\": 549, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -1.9556, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -3.2497, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"V\", \"escape\": -0.01639398420662619, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -1.0027, \"times_seen\": 8.0}, {\"site\": 549, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"552\", \"functional effect\": -3.0461, \"times_seen\": null}, {\"site\": 550, \"mutant\": \"A\", \"escape\": -0.0019183674502522173, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.3807, \"times_seen\": 6.0}, {\"site\": 550, \"mutant\": \"G\", \"escape\": 0.0008101352904473166, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -2.9624, \"times_seen\": 1.0}, {\"site\": 550, \"mutant\": \"I\", \"escape\": -0.09152572167543786, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.3628, \"times_seen\": 16.0}, {\"site\": 550, \"mutant\": \"K\", \"escape\": 0.00361360739213655, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -0.9838, \"times_seen\": 10.0}, {\"site\": 550, \"mutant\": \"L\", \"escape\": -0.003938429098984385, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -0.9395, \"times_seen\": 1.0}, {\"site\": 550, \"mutant\": \"N\", \"escape\": -0.0006658957036125282, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.3033, \"times_seen\": 1.0}, {\"site\": 550, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -2.0618, \"times_seen\": null}, {\"site\": 550, \"mutant\": \"S\", \"escape\": 0.006474946195155162, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -0.3906, \"times_seen\": 3.0}, {\"site\": 550, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 550, \"mutant\": \"V\", \"escape\": -0.003884474951826445, \"epitope\": \"epitope 1\", \"reference_site\": \"553\", \"functional effect\": -1.8571, \"times_seen\": 2.0}, {\"site\": 551, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 551, \"mutant\": \"A\", \"escape\": -0.019763951106353234, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": 0.3314, \"times_seen\": 9.0}, {\"site\": 551, \"mutant\": \"D\", \"escape\": 0.09976360495050945, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.0665, \"times_seen\": 22.0}, {\"site\": 551, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 551, \"mutant\": \"G\", \"escape\": -0.0620917607264692, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.3478, \"times_seen\": 28.0}, {\"site\": 551, \"mutant\": \"K\", \"escape\": -0.014001680431118236, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.0396, \"times_seen\": 25.0}, {\"site\": 551, \"mutant\": \"L\", \"escape\": -0.012321832930824962, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.8793, \"times_seen\": 3.0}, {\"site\": 551, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -2.7917, \"times_seen\": null}, {\"site\": 551, \"mutant\": \"Q\", \"escape\": 0.02547709720327268, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.2673, \"times_seen\": 8.0}, {\"site\": 551, \"mutant\": \"R\", \"escape\": -0.02930922766064922, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.203, \"times_seen\": 8.0}, {\"site\": 551, \"mutant\": \"S\", \"escape\": 0.00634481986375391, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.2402, \"times_seen\": 1.0}, {\"site\": 551, \"mutant\": \"V\", \"escape\": -0.0373113186903611, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -0.5543, \"times_seen\": 21.0}, {\"site\": 551, \"mutant\": \"W\", \"escape\": -0.004949899812003328, \"epitope\": \"epitope 1\", \"reference_site\": \"554\", \"functional effect\": -2.6839, \"times_seen\": 2.0}, {\"site\": 552, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -3.0124, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"G\", \"escape\": -0.004736064855527372, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 552, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -3.1316, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -1.6653, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"R\", \"escape\": -0.0004223970348872953, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.2021, \"times_seen\": 1.0}, {\"site\": 552, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"T\", \"escape\": -0.008277855979110089, \"epitope\": \"epitope 1\", \"reference_site\": \"555\", \"functional effect\": -2.7942, \"times_seen\": 1.0}, {\"site\": 553, \"mutant\": \"D\", \"escape\": -0.778480143828341, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.5338, \"times_seen\": 13.0}, {\"site\": 553, \"mutant\": \"I\", \"escape\": 0.008218006494110962, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.7417, \"times_seen\": 10.0}, {\"site\": 553, \"mutant\": \"K\", \"escape\": 0.05477317897389411, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": 0.306, \"times_seen\": 34.0}, {\"site\": 553, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 553, \"mutant\": \"P\", \"escape\": -0.026094215731013542, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.7034, \"times_seen\": 8.0}, {\"site\": 553, \"mutant\": \"S\", \"escape\": 0.23177506444183602, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.1276, \"times_seen\": 28.0}, {\"site\": 553, \"mutant\": \"T\", \"escape\": -0.01054386458430113, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.0048, \"times_seen\": 8.0}, {\"site\": 553, \"mutant\": \"V\", \"escape\": -0.010335427860641755, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.371, \"times_seen\": 3.0}, {\"site\": 553, \"mutant\": \"Y\", \"escape\": -0.0007833101961572761, \"epitope\": \"epitope 1\", \"reference_site\": \"556\", \"functional effect\": -0.3633, \"times_seen\": 9.0}, {\"site\": 554, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.2885, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"L\", \"escape\": -0.0037544289500637583, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -1.5022, \"times_seen\": 1.0}, {\"site\": 554, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.9281, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.5397, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"Q\", \"escape\": 0.02639901532469486, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.5659, \"times_seen\": 1.0}, {\"site\": 554, \"mutant\": \"R\", \"escape\": 0.01171631363657165, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -0.1764, \"times_seen\": 2.0}, {\"site\": 554, \"mutant\": \"T\", \"escape\": -0.1727346630801712, \"epitope\": \"epitope 1\", \"reference_site\": \"557\", \"functional effect\": -2.1692, \"times_seen\": 2.0}, {\"site\": 555, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -2.0148, \"times_seen\": null}, {\"site\": 555, \"mutant\": \"E\", \"escape\": -0.010384561178325643, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -1.6942, \"times_seen\": 7.0}, {\"site\": 555, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 555, \"mutant\": \"M\", \"escape\": -0.004608299124920066, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.1471, \"times_seen\": 5.0}, {\"site\": 555, \"mutant\": \"N\", \"escape\": -0.02461931423437369, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.3473, \"times_seen\": 37.0}, {\"site\": 555, \"mutant\": \"P\", \"escape\": -0.003290908405703505, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.0113, \"times_seen\": 1.0}, {\"site\": 555, \"mutant\": \"Q\", \"escape\": -1.997021698179498e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.0286, \"times_seen\": 1.0}, {\"site\": 555, \"mutant\": \"R\", \"escape\": 0.018660352636932182, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.0761, \"times_seen\": 29.0}, {\"site\": 555, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.385, \"times_seen\": null}, {\"site\": 555, \"mutant\": \"T\", \"escape\": 0.006266691694234266, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -0.2543, \"times_seen\": 3.0}, {\"site\": 555, \"mutant\": \"W\", \"escape\": 0.016509221645661223, \"epitope\": \"epitope 1\", \"reference_site\": \"558\", \"functional effect\": -2.0137, \"times_seen\": 2.0}, {\"site\": 556, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"G\", \"escape\": 0.001928948009517977, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.94, \"times_seen\": 1.0}, {\"site\": 556, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -1.1, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"L\", \"escape\": 0.018112705056511, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.0562, \"times_seen\": 1.0}, {\"site\": 556, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -1.2662, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.924, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -0.4951, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"559\", \"functional effect\": -2.585, \"times_seen\": null}, {\"site\": 557, \"mutant\": \"C\", \"escape\": -0.014328142746605722, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -2.3067, \"times_seen\": 1.0}, {\"site\": 557, \"mutant\": \"G\", \"escape\": -0.004034835333523823, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -2.8505, \"times_seen\": 1.0}, {\"site\": 557, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 557, \"mutant\": \"M\", \"escape\": -0.020489280761232805, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": 0.0426, \"times_seen\": 22.0}, {\"site\": 557, \"mutant\": \"P\", \"escape\": -0.023633183732052438, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -2.8971, \"times_seen\": 8.0}, {\"site\": 557, \"mutant\": \"Q\", \"escape\": 0.004768852142715863, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -0.1031, \"times_seen\": 9.0}, {\"site\": 557, \"mutant\": \"R\", \"escape\": -0.0002477395899439544, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": 0.0248, \"times_seen\": 1.0}, {\"site\": 557, \"mutant\": \"S\", \"escape\": -0.015577336970049016, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -1.37, \"times_seen\": 4.0}, {\"site\": 557, \"mutant\": \"W\", \"escape\": -0.027028017234874926, \"epitope\": \"epitope 1\", \"reference_site\": \"560\", \"functional effect\": -1.0651, \"times_seen\": 6.0}, {\"site\": 558, \"mutant\": \"A\", \"escape\": 0.005984161506712739, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.3296, \"times_seen\": 4.0}, {\"site\": 558, \"mutant\": \"G\", \"escape\": 0.008477753514871166, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.5628, \"times_seen\": 1.0}, {\"site\": 558, \"mutant\": \"H\", \"escape\": 1.9746594182731096, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.3695, \"times_seen\": 8.0}, {\"site\": 558, \"mutant\": \"L\", \"escape\": -0.0023297840674836195, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -2.3594, \"times_seen\": 5.0}, {\"site\": 558, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 558, \"mutant\": \"Q\", \"escape\": 0.012809986695951195, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.5895, \"times_seen\": 3.0}, {\"site\": 558, \"mutant\": \"S\", \"escape\": 0.019252549212280173, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.3134, \"times_seen\": 21.0}, {\"site\": 558, \"mutant\": \"T\", \"escape\": -0.002305076125702281, \"epitope\": \"epitope 1\", \"reference_site\": \"561\", \"functional effect\": -0.603, \"times_seen\": 3.0}, {\"site\": 559, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 559, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -3.1555, \"times_seen\": null}, {\"site\": 559, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -3.0884, \"times_seen\": null}, {\"site\": 559, \"mutant\": \"S\", \"escape\": -0.0021279789619515297, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -2.9764, \"times_seen\": 2.0}, {\"site\": 559, \"mutant\": \"W\", \"escape\": -0.009407452046904538, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 559, \"mutant\": \"Y\", \"escape\": -0.0037419014220246073, \"epitope\": \"epitope 1\", \"reference_site\": \"562\", \"functional effect\": -2.777, \"times_seen\": 1.0}, {\"site\": 560, \"mutant\": \"*\", \"escape\": -0.003395577198036948, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.3202, \"times_seen\": 1.0}, {\"site\": 560, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.4618, \"times_seen\": null}, {\"site\": 560, \"mutant\": \"K\", \"escape\": -0.0024947456659428803, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.927, \"times_seen\": 1.0}, {\"site\": 560, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 560, \"mutant\": \"R\", \"escape\": -0.00382927368806498, \"epitope\": \"epitope 1\", \"reference_site\": \"563\", \"functional effect\": -2.9788, \"times_seen\": 1.0}, {\"site\": 561, \"mutant\": \"*\", \"escape\": -0.004898181266233891, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -1.592, \"times_seen\": 3.0}, {\"site\": 561, \"mutant\": \"E\", \"escape\": 0.08054773972049933, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -2.4726, \"times_seen\": 5.0}, {\"site\": 561, \"mutant\": \"H\", \"escape\": -0.019292827247766185, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": 0.2282, \"times_seen\": 5.0}, {\"site\": 561, \"mutant\": \"K\", \"escape\": 0.022272383111804985, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -1.6206, \"times_seen\": 4.0}, {\"site\": 561, \"mutant\": \"L\", \"escape\": 0.04213293460382326, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -0.7601, \"times_seen\": 8.0}, {\"site\": 561, \"mutant\": \"P\", \"escape\": -0.006603515444310673, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -2.4087, \"times_seen\": 1.0}, {\"site\": 561, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 561, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": -0.38, \"times_seen\": null}, {\"site\": 561, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"564\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 562, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -2.3316, \"times_seen\": null}, {\"site\": 562, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 562, \"mutant\": \"I\", \"escape\": -0.003995774346583196, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": 0.2389, \"times_seen\": 2.0}, {\"site\": 562, \"mutant\": \"L\", \"escape\": -0.005903034007747922, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -0.4081, \"times_seen\": 10.0}, {\"site\": 562, \"mutant\": \"S\", \"escape\": -0.03833731907733855, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -0.9586, \"times_seen\": 3.0}, {\"site\": 562, \"mutant\": \"V\", \"escape\": 0.005146275661641307, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": 0.2013, \"times_seen\": 7.0}, {\"site\": 562, \"mutant\": \"Y\", \"escape\": 0.0068446676839394385, \"epitope\": \"epitope 1\", \"reference_site\": \"565\", \"functional effect\": -0.0016, \"times_seen\": 6.0}, {\"site\": 563, \"mutant\": \"-\", \"escape\": -0.010752828109212829, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 563, \"mutant\": \"A\", \"escape\": -0.028751017659760937, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -1.6099, \"times_seen\": 7.0}, {\"site\": 563, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -2.9434, \"times_seen\": null}, {\"site\": 563, \"mutant\": \"D\", \"escape\": -0.49789430213950053, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -2.1732, \"times_seen\": 2.0}, {\"site\": 563, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 563, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -0.5665, \"times_seen\": null}, {\"site\": 563, \"mutant\": \"S\", \"escape\": -0.09059402166246988, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -0.7948, \"times_seen\": 21.0}, {\"site\": 563, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"566\", \"functional effect\": -2.3366, \"times_seen\": null}, {\"site\": 564, \"mutant\": \"-\", \"escape\": -0.0017546955005495648, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 564, \"mutant\": \"G\", \"escape\": -0.01773630704235072, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -2.5503, \"times_seen\": 9.0}, {\"site\": 564, \"mutant\": \"I\", \"escape\": 0.0028362022877574584, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.1, \"times_seen\": 11.0}, {\"site\": 564, \"mutant\": \"K\", \"escape\": 0.6000189139915549, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": 0.0704, \"times_seen\": 30.0}, {\"site\": 564, \"mutant\": \"M\", \"escape\": 0.005624596571317102, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.4411, \"times_seen\": 11.0}, {\"site\": 564, \"mutant\": \"N\", \"escape\": -0.0018988902916340215, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.3508, \"times_seen\": 4.0}, {\"site\": 564, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 564, \"mutant\": \"S\", \"escape\": -0.12040025304652735, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -1.2128, \"times_seen\": 8.0}, {\"site\": 564, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.4161, \"times_seen\": null}, {\"site\": 564, \"mutant\": \"W\", \"escape\": 3.7623963020795245e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"567\", \"functional effect\": -0.1585, \"times_seen\": 3.0}, {\"site\": 565, \"mutant\": \"-\", \"escape\": -0.003475430503188779, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 565, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 565, \"mutant\": \"E\", \"escape\": -0.006512103756307568, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -1.9319, \"times_seen\": 3.0}, {\"site\": 565, \"mutant\": \"G\", \"escape\": -0.00846385465130695, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -1.7188, \"times_seen\": 8.0}, {\"site\": 565, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 565, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -1.5973, \"times_seen\": null}, {\"site\": 565, \"mutant\": \"N\", \"escape\": -0.016969042156890775, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -2.0757, \"times_seen\": 9.0}, {\"site\": 565, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"568\", \"functional effect\": -3.0982, \"times_seen\": null}, {\"site\": 566, \"mutant\": \"-\", \"escape\": -0.0032987534096699843, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 566, \"mutant\": \"F\", \"escape\": -0.016842160129945525, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -1.2127, \"times_seen\": 11.0}, {\"site\": 566, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 566, \"mutant\": \"L\", \"escape\": -0.018198925478032174, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": 0.0508, \"times_seen\": 7.0}, {\"site\": 566, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -1.5911, \"times_seen\": null}, {\"site\": 566, \"mutant\": \"S\", \"escape\": -0.009850718701187195, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.8953, \"times_seen\": 9.0}, {\"site\": 566, \"mutant\": \"T\", \"escape\": 0.005819652064218948, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.4726, \"times_seen\": 6.0}, {\"site\": 566, \"mutant\": \"V\", \"escape\": 0.005568051855120982, \"epitope\": \"epitope 1\", \"reference_site\": \"569\", \"functional effect\": -0.0367, \"times_seen\": 23.0}, {\"site\": 567, \"mutant\": \"*\", \"escape\": -0.00040229072635925684, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.7409, \"times_seen\": 2.0}, {\"site\": 567, \"mutant\": \"-\", \"escape\": -0.002886628112478006, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 567, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 567, \"mutant\": \"C\", \"escape\": 0.06822838126861865, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.8571, \"times_seen\": 7.0}, {\"site\": 567, \"mutant\": \"D\", \"escape\": -0.03683554373442995, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.3645, \"times_seen\": 13.0}, {\"site\": 567, \"mutant\": \"E\", \"escape\": -0.003360662777035951, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.8609, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"F\", \"escape\": 0.007864946542746536, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.2365, \"times_seen\": 14.0}, {\"site\": 567, \"mutant\": \"G\", \"escape\": -0.12266629378101356, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -1.323, \"times_seen\": 63.0}, {\"site\": 567, \"mutant\": \"H\", \"escape\": -0.005631463800042115, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.6726, \"times_seen\": 2.0}, {\"site\": 567, \"mutant\": \"I\", \"escape\": 0.07741235265806706, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.3606, \"times_seen\": 8.0}, {\"site\": 567, \"mutant\": \"K\", \"escape\": 0.023764147768287516, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.0229, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"L\", \"escape\": 0.03596463450283188, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.2957, \"times_seen\": 14.0}, {\"site\": 567, \"mutant\": \"M\", \"escape\": 0.008081115240383933, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.9093, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"N\", \"escape\": -0.0018244756046729193, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.6227, \"times_seen\": 2.0}, {\"site\": 567, \"mutant\": \"P\", \"escape\": -0.0073107453605038225, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.4414, \"times_seen\": 7.0}, {\"site\": 567, \"mutant\": \"Q\", \"escape\": -0.014132264608272783, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.5472, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"R\", \"escape\": -0.00016071836213378714, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.621, \"times_seen\": 11.0}, {\"site\": 567, \"mutant\": \"S\", \"escape\": 0.7132478450074761, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -0.1169, \"times_seen\": 140.0}, {\"site\": 567, \"mutant\": \"T\", \"escape\": 0.29325105561511633, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": 0.0316, \"times_seen\": 138.0}, {\"site\": 567, \"mutant\": \"V\", \"escape\": -0.4370196465258321, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -1.4471, \"times_seen\": 88.0}, {\"site\": 567, \"mutant\": \"W\", \"escape\": -0.005969308024027936, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -2.4598, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"Y\", \"escape\": -0.02650331548446641, \"epitope\": \"epitope 1\", \"reference_site\": \"570\", \"functional effect\": -1.6172, \"times_seen\": 34.0}, {\"site\": 568, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 568, \"mutant\": \"E\", \"escape\": 0.034149013782174956, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -0.0272, \"times_seen\": 14.0}, {\"site\": 568, \"mutant\": \"G\", \"escape\": -0.032573707808527703, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": 0.0333, \"times_seen\": 23.0}, {\"site\": 568, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -2.0259, \"times_seen\": null}, {\"site\": 568, \"mutant\": \"N\", \"escape\": -0.014624009368199109, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -3.0583, \"times_seen\": 2.0}, {\"site\": 568, \"mutant\": \"Y\", \"escape\": -0.5764130170857507, \"epitope\": \"epitope 1\", \"reference_site\": \"571\", \"functional effect\": -2.0572, \"times_seen\": 20.0}, {\"site\": 569, \"mutant\": \"*\", \"escape\": -0.016447601065351692, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -2.7558, \"times_seen\": 1.0}, {\"site\": 569, \"mutant\": \"A\", \"escape\": -0.023526120930850776, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.1502, \"times_seen\": 45.0}, {\"site\": 569, \"mutant\": \"C\", \"escape\": -0.015117848206352221, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.1717, \"times_seen\": 13.0}, {\"site\": 569, \"mutant\": \"D\", \"escape\": 0.01759176550732054, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2113, \"times_seen\": 7.0}, {\"site\": 569, \"mutant\": \"E\", \"escape\": 0.005448454725713032, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2738, \"times_seen\": 12.0}, {\"site\": 569, \"mutant\": \"F\", \"escape\": 0.03010691290594441, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.1425, \"times_seen\": 5.0}, {\"site\": 569, \"mutant\": \"G\", \"escape\": 0.18322024711057158, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.3767, \"times_seen\": 51.0}, {\"site\": 569, \"mutant\": \"H\", \"escape\": -0.8964608694932198, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.3283, \"times_seen\": 17.0}, {\"site\": 569, \"mutant\": \"I\", \"escape\": 0.041658533935439786, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2776, \"times_seen\": 28.0}, {\"site\": 569, \"mutant\": \"K\", \"escape\": -0.9685312020192811, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.401, \"times_seen\": 12.0}, {\"site\": 569, \"mutant\": \"L\", \"escape\": 0.06735824775686507, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.1166, \"times_seen\": 24.0}, {\"site\": 569, \"mutant\": \"M\", \"escape\": -0.025497024755617218, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.0921, \"times_seen\": 16.0}, {\"site\": 569, \"mutant\": \"N\", \"escape\": -0.00035275441877414984, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -1.2249, \"times_seen\": 48.0}, {\"site\": 569, \"mutant\": \"P\", \"escape\": -0.009078805400483779, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -2.7875, \"times_seen\": 2.0}, {\"site\": 569, \"mutant\": \"Q\", \"escape\": -0.011771421099840248, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.3372, \"times_seen\": 13.0}, {\"site\": 569, \"mutant\": \"R\", \"escape\": -0.14504501833700334, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.6641, \"times_seen\": 53.0}, {\"site\": 569, \"mutant\": \"S\", \"escape\": -0.06363087851439773, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.1456, \"times_seen\": 57.0}, {\"site\": 569, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 569, \"mutant\": \"V\", \"escape\": -0.08184538274959959, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.7735, \"times_seen\": 19.0}, {\"site\": 569, \"mutant\": \"W\", \"escape\": 0.028887755275337983, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.502, \"times_seen\": 13.0}, {\"site\": 569, \"mutant\": \"Y\", \"escape\": -0.019776882992352408, \"epitope\": \"epitope 1\", \"reference_site\": \"572\", \"functional effect\": -0.0262, \"times_seen\": 19.0}, {\"site\": 570, \"mutant\": \"A\", \"escape\": -0.007044502838592017, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.4135, \"times_seen\": 8.0}, {\"site\": 570, \"mutant\": \"I\", \"escape\": -0.024306117232161126, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": 0.2755, \"times_seen\": 31.0}, {\"site\": 570, \"mutant\": \"K\", \"escape\": -0.012118472736104918, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.3074, \"times_seen\": 3.0}, {\"site\": 570, \"mutant\": \"L\", \"escape\": -0.009794531699282313, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": 0.2203, \"times_seen\": 4.0}, {\"site\": 570, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.5474, \"times_seen\": null}, {\"site\": 570, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.3033, \"times_seen\": null}, {\"site\": 570, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": -1.4348, \"times_seen\": null}, {\"site\": 570, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"573\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 571, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 571, \"mutant\": \"E\", \"escape\": -0.0022823475862235837, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -2.1183, \"times_seen\": 1.0}, {\"site\": 571, \"mutant\": \"G\", \"escape\": -0.004385017847984853, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 571, \"mutant\": \"H\", \"escape\": -0.02470168198977676, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -1.7645, \"times_seen\": 6.0}, {\"site\": 571, \"mutant\": \"N\", \"escape\": -0.06669322658892059, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": 0.397, \"times_seen\": 41.0}, {\"site\": 571, \"mutant\": \"V\", \"escape\": 0.012164807835379762, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -0.6174, \"times_seen\": 5.0}, {\"site\": 571, \"mutant\": \"Y\", \"escape\": 0.017964895976396812, \"epitope\": \"epitope 1\", \"reference_site\": \"574\", \"functional effect\": -2.0659, \"times_seen\": 16.0}, {\"site\": 572, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 572, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -3.0047, \"times_seen\": null}, {\"site\": 572, \"mutant\": \"G\", \"escape\": 0.002849084545383419, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -2.1062, \"times_seen\": 7.0}, {\"site\": 572, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": 0.7078, \"times_seen\": null}, {\"site\": 572, \"mutant\": \"S\", \"escape\": -0.9191156594395485, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": 0.1167, \"times_seen\": 57.0}, {\"site\": 572, \"mutant\": \"T\", \"escape\": -0.02528353579788134, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -1.6023, \"times_seen\": 29.0}, {\"site\": 572, \"mutant\": \"V\", \"escape\": -0.004980735311366812, \"epitope\": \"epitope 1\", \"reference_site\": \"575\", \"functional effect\": -2.2746, \"times_seen\": 11.0}, {\"site\": 573, \"mutant\": \"A\", \"escape\": -0.0018644765679104278, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -2.0367, \"times_seen\": 1.0}, {\"site\": 573, \"mutant\": \"F\", \"escape\": 0.0005198523200486474, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -2.8705, \"times_seen\": 1.0}, {\"site\": 573, \"mutant\": \"I\", \"escape\": -0.012712289502729719, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": 0.2586, \"times_seen\": 25.0}, {\"site\": 573, \"mutant\": \"L\", \"escape\": 0.019906992973909642, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -0.7482, \"times_seen\": 4.0}, {\"site\": 573, \"mutant\": \"M\", \"escape\": 0.006983431598214905, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": -1.4259, \"times_seen\": 4.0}, {\"site\": 573, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"576\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 574, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.8795, \"times_seen\": null}, {\"site\": 574, \"mutant\": \"G\", \"escape\": 0.0030792308264445544, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.4292, \"times_seen\": 5.0}, {\"site\": 574, \"mutant\": \"K\", \"escape\": -0.013539146782364373, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -0.2346, \"times_seen\": 17.0}, {\"site\": 574, \"mutant\": \"L\", \"escape\": -0.039111975681851284, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -1.9766, \"times_seen\": 2.0}, {\"site\": 574, \"mutant\": \"M\", \"escape\": -0.015070622651923321, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.1163, \"times_seen\": 10.0}, {\"site\": 574, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 574, \"mutant\": \"S\", \"escape\": -0.00488583149831138, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -2.9583, \"times_seen\": 2.0}, {\"site\": 574, \"mutant\": \"W\", \"escape\": -0.0038356849254135633, \"epitope\": \"epitope 1\", \"reference_site\": \"577\", \"functional effect\": -1.2552, \"times_seen\": 1.0}, {\"site\": 575, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -3.0225, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -3.085, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"N\", \"escape\": -0.004434795834571382, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -2.333, \"times_seen\": 2.0}, {\"site\": 575, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"578\", \"functional effect\": -2.8685, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -1.6729, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"L\", \"escape\": -0.0023604164133815405, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -0.8443, \"times_seen\": 1.0}, {\"site\": 576, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"Q\", \"escape\": 0.017672362654817125, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -2.2045, \"times_seen\": 1.0}, {\"site\": 576, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -2.1658, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"579\", \"functional effect\": -2.6607, \"times_seen\": null}, {\"site\": 577, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -2.4574, \"times_seen\": null}, {\"site\": 577, \"mutant\": \"E\", \"escape\": -0.006915720680379966, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -0.9949, \"times_seen\": 5.0}, {\"site\": 577, \"mutant\": \"H\", \"escape\": -0.058778470291607536, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -1.1274, \"times_seen\": 22.0}, {\"site\": 577, \"mutant\": \"K\", \"escape\": -0.0031966028658219695, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -0.185, \"times_seen\": 9.0}, {\"site\": 577, \"mutant\": \"L\", \"escape\": -0.07076238842984621, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": 0.0657, \"times_seen\": 53.0}, {\"site\": 577, \"mutant\": \"M\", \"escape\": -0.025837968015617788, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": 0.2053, \"times_seen\": 5.0}, {\"site\": 577, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 577, \"mutant\": \"R\", \"escape\": -0.08978639304965136, \"epitope\": \"epitope 1\", \"reference_site\": \"580\", \"functional effect\": -0.0238, \"times_seen\": 44.0}, {\"site\": 578, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": 0.0867, \"times_seen\": null}, {\"site\": 578, \"mutant\": \"I\", \"escape\": 0.010539560098036969, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": -2.5045, \"times_seen\": 5.0}, {\"site\": 578, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": -0.8684, \"times_seen\": null}, {\"site\": 578, \"mutant\": \"S\", \"escape\": -0.04128764473421178, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": -0.5312, \"times_seen\": 20.0}, {\"site\": 578, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"581\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 579, \"mutant\": \"F\", \"escape\": -0.7733054331726249, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.0603, \"times_seen\": 48.0}, {\"site\": 579, \"mutant\": \"H\", \"escape\": -0.014077071195626211, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.3607, \"times_seen\": 3.0}, {\"site\": 579, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 579, \"mutant\": \"M\", \"escape\": -0.007330196242910517, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": -0.0263, \"times_seen\": 2.0}, {\"site\": 579, \"mutant\": \"S\", \"escape\": 0.02426346728805838, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": 0.3336, \"times_seen\": 6.0}, {\"site\": 579, \"mutant\": \"V\", \"escape\": 0.029465069887978652, \"epitope\": \"epitope 1\", \"reference_site\": \"582\", \"functional effect\": -3.2007, \"times_seen\": 1.0}, {\"site\": 580, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.4807, \"times_seen\": null}, {\"site\": 580, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 580, \"mutant\": \"A\", \"escape\": -0.010319653133777572, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.1563, \"times_seen\": 3.0}, {\"site\": 580, \"mutant\": \"D\", \"escape\": -0.017676678672780374, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.0418, \"times_seen\": 15.0}, {\"site\": 580, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 580, \"mutant\": \"G\", \"escape\": -0.005349184010336788, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -2.4049, \"times_seen\": 2.0}, {\"site\": 580, \"mutant\": \"K\", \"escape\": 0.02508466678852754, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -1.3008, \"times_seen\": 17.0}, {\"site\": 580, \"mutant\": \"L\", \"escape\": -0.003528758289459847, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -3.0176, \"times_seen\": 1.0}, {\"site\": 580, \"mutant\": \"Q\", \"escape\": -0.04335881859705863, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -0.8469, \"times_seen\": 12.0}, {\"site\": 580, \"mutant\": \"V\", \"escape\": 0.008721112470945326, \"epitope\": \"epitope 1\", \"reference_site\": \"583\", \"functional effect\": -2.1047, \"times_seen\": 4.0}, {\"site\": 581, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"F\", \"escape\": 0.014861251803938475, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -2.627, \"times_seen\": 1.0}, {\"site\": 581, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"M\", \"escape\": -0.009302071018024795, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -2.6452, \"times_seen\": 3.0}, {\"site\": 581, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -3.0759, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"T\", \"escape\": -0.0023508030842747133, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": -2.0253, \"times_seen\": 1.0}, {\"site\": 581, \"mutant\": \"V\", \"escape\": -0.01654717123015256, \"epitope\": \"epitope 1\", \"reference_site\": \"584\", \"functional effect\": 0.3752, \"times_seen\": 9.0}, {\"site\": 582, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"F\", \"escape\": -0.001473663967985633, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -1.1432, \"times_seen\": 16.0}, {\"site\": 582, \"mutant\": \"I\", \"escape\": -0.11763264092509686, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -0.1092, \"times_seen\": 11.0}, {\"site\": 582, \"mutant\": \"K\", \"escape\": -0.017080434779081544, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 582, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"M\", \"escape\": 0.007174840418455012, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -0.8359, \"times_seen\": 14.0}, {\"site\": 582, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -3.0671, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": -1.8692, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"V\", \"escape\": -0.002642475314359522, \"epitope\": \"epitope 1\", \"reference_site\": \"585\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 583, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 583, \"mutant\": \"E\", \"escape\": 0.02669137009512429, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.4963, \"times_seen\": 6.0}, {\"site\": 583, \"mutant\": \"G\", \"escape\": -0.005263498228074246, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.31, \"times_seen\": 2.0}, {\"site\": 583, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.6565, \"times_seen\": null}, {\"site\": 583, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -3.0571, \"times_seen\": null}, {\"site\": 583, \"mutant\": \"N\", \"escape\": -0.03238204469100857, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -0.2218, \"times_seen\": 14.0}, {\"site\": 583, \"mutant\": \"S\", \"escape\": -0.015618288942562139, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -0.7711, \"times_seen\": 6.0}, {\"site\": 583, \"mutant\": \"T\", \"escape\": -0.003412663660415303, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -0.6072, \"times_seen\": 3.0}, {\"site\": 583, \"mutant\": \"W\", \"escape\": -0.013418935062560125, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -2.9842, \"times_seen\": 2.0}, {\"site\": 583, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"586\", \"functional effect\": -1.7541, \"times_seen\": null}, {\"site\": 584, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 584, \"mutant\": \"G\", \"escape\": -0.00261956904852177, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -2.9847, \"times_seen\": 1.0}, {\"site\": 584, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 584, \"mutant\": \"L\", \"escape\": -0.009004879587729499, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -1.7824, \"times_seen\": 2.0}, {\"site\": 584, \"mutant\": \"N\", \"escape\": -0.005044219609830844, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -2.7277, \"times_seen\": 1.0}, {\"site\": 584, \"mutant\": \"T\", \"escape\": -0.003052679212511334, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -2.2331, \"times_seen\": 2.0}, {\"site\": 584, \"mutant\": \"V\", \"escape\": -0.008172736455135535, \"epitope\": \"epitope 1\", \"reference_site\": \"587\", \"functional effect\": -1.6721, \"times_seen\": 3.0}, {\"site\": 585, \"mutant\": \"A\", \"escape\": 0.07022106762032866, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.7151, \"times_seen\": 14.0}, {\"site\": 585, \"mutant\": \"I\", \"escape\": -0.6538398781203425, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -1.1483, \"times_seen\": 22.0}, {\"site\": 585, \"mutant\": \"K\", \"escape\": -0.03072565528861926, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.6462, \"times_seen\": 10.0}, {\"site\": 585, \"mutant\": \"R\", \"escape\": -0.009750756942772517, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": 0.0031, \"times_seen\": 3.0}, {\"site\": 585, \"mutant\": \"S\", \"escape\": -0.009397900232015597, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.4023, \"times_seen\": 5.0}, {\"site\": 585, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 585, \"mutant\": \"V\", \"escape\": -0.009367427056987763, \"epitope\": \"epitope 1\", \"reference_site\": \"588\", \"functional effect\": -0.4268, \"times_seen\": 5.0}, {\"site\": 586, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.6176, \"times_seen\": null}, {\"site\": 586, \"mutant\": \"H\", \"escape\": -0.003082421463919978, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.8352, \"times_seen\": 1.0}, {\"site\": 586, \"mutant\": \"L\", \"escape\": -0.005946680373980233, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.9777, \"times_seen\": 2.0}, {\"site\": 586, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 586, \"mutant\": \"Q\", \"escape\": -0.0007362255247596066, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.5671, \"times_seen\": 2.0}, {\"site\": 586, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.9764, \"times_seen\": null}, {\"site\": 586, \"mutant\": \"S\", \"escape\": 0.025283609126854206, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.3969, \"times_seen\": 5.0}, {\"site\": 586, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"589\", \"functional effect\": -2.5191, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9546, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"L\", \"escape\": -0.004379699082815736, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9043, \"times_seen\": 1.0}, {\"site\": 587, \"mutant\": \"R\", \"escape\": -0.008714931040123594, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9197, \"times_seen\": 3.0}, {\"site\": 587, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"Y\", \"escape\": -0.0033712233111398635, \"epitope\": \"epitope 1\", \"reference_site\": \"590\", \"functional effect\": -2.9917, \"times_seen\": 1.0}, {\"site\": 588, \"mutant\": \"A\", \"escape\": 0.026612382451800354, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -0.3383, \"times_seen\": 4.0}, {\"site\": 588, \"mutant\": \"C\", \"escape\": -0.0010391990854108797, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -0.936, \"times_seen\": 1.0}, {\"site\": 588, \"mutant\": \"F\", \"escape\": -0.022821527043356955, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.3641, \"times_seen\": 28.0}, {\"site\": 588, \"mutant\": \"H\", \"escape\": 0.026495592173464057, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": 0.07, \"times_seen\": 6.0}, {\"site\": 588, \"mutant\": \"L\", \"escape\": -0.004307040626665393, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.8018, \"times_seen\": 2.0}, {\"site\": 588, \"mutant\": \"P\", \"escape\": 0.015103098915369298, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.303, \"times_seen\": 6.0}, {\"site\": 588, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 588, \"mutant\": \"T\", \"escape\": 0.027218537325898042, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -0.2819, \"times_seen\": 10.0}, {\"site\": 588, \"mutant\": \"Y\", \"escape\": -0.002125005858096017, \"epitope\": \"epitope 1\", \"reference_site\": \"591\", \"functional effect\": -1.843, \"times_seen\": 3.0}, {\"site\": 589, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 589, \"mutant\": \"I\", \"escape\": -0.7164627089189333, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.971, \"times_seen\": 2.0}, {\"site\": 589, \"mutant\": \"L\", \"escape\": -0.017438716863431493, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.4882, \"times_seen\": 4.0}, {\"site\": 589, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 589, \"mutant\": \"P\", \"escape\": -0.00554587523490375, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.8179, \"times_seen\": 1.0}, {\"site\": 589, \"mutant\": \"S\", \"escape\": 0.004640546571522106, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -0.25, \"times_seen\": 20.0}, {\"site\": 589, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -2.9925, \"times_seen\": null}, {\"site\": 589, \"mutant\": \"Y\", \"escape\": 0.033450923217676384, \"epitope\": \"epitope 1\", \"reference_site\": \"592\", \"functional effect\": -0.2666, \"times_seen\": 2.0}, {\"site\": 590, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -3.1088, \"times_seen\": null}, {\"site\": 590, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.8569, \"times_seen\": null}, {\"site\": 590, \"mutant\": \"C\", \"escape\": -0.004028280603704459, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.2492, \"times_seen\": 1.0}, {\"site\": 590, \"mutant\": \"E\", \"escape\": -0.003945947950485575, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -2.9055, \"times_seen\": 1.0}, {\"site\": 590, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 590, \"mutant\": \"R\", \"escape\": -0.02316378840886828, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -2.2234, \"times_seen\": 8.0}, {\"site\": 590, \"mutant\": \"S\", \"escape\": -0.011385832223383033, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.7069, \"times_seen\": 5.0}, {\"site\": 590, \"mutant\": \"V\", \"escape\": -0.06332881696424283, \"epitope\": \"epitope 1\", \"reference_site\": \"593\", \"functional effect\": -1.6035, \"times_seen\": 7.0}, {\"site\": 591, \"mutant\": \"*\", \"escape\": 0.001149512677854969, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -2.0412, \"times_seen\": 2.0}, {\"site\": 591, \"mutant\": \"D\", \"escape\": 0.00385475510533339, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -1.2151, \"times_seen\": 5.0}, {\"site\": 591, \"mutant\": \"E\", \"escape\": -0.001736775232711429, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -0.7032, \"times_seen\": 10.0}, {\"site\": 591, \"mutant\": \"F\", \"escape\": 0.0077494879044808515, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -0.9029, \"times_seen\": 6.0}, {\"site\": 591, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 591, \"mutant\": \"R\", \"escape\": 0.004903215908691853, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -0.7007, \"times_seen\": 17.0}, {\"site\": 591, \"mutant\": \"S\", \"escape\": -0.0028127849824187566, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": 0.0355, \"times_seen\": 13.0}, {\"site\": 591, \"mutant\": \"V\", \"escape\": -0.002564906010405518, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -2.1905, \"times_seen\": 6.0}, {\"site\": 591, \"mutant\": \"W\", \"escape\": -0.005695471341409223, \"epitope\": \"epitope 1\", \"reference_site\": \"594\", \"functional effect\": -1.4738, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"A\", \"escape\": -0.020241888443939645, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.8661, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"E\", \"escape\": 0.01958409173774922, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -2.6389, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"G\", \"escape\": -0.0017211869635473207, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.5895, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"I\", \"escape\": 0.03195678834903079, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.1331, \"times_seen\": 6.0}, {\"site\": 592, \"mutant\": \"L\", \"escape\": -0.0033342748855382355, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -0.7692, \"times_seen\": 5.0}, {\"site\": 592, \"mutant\": \"M\", \"escape\": -0.0044851681899428465, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": -3.0332, \"times_seen\": 2.0}, {\"site\": 592, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"595\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 593, \"mutant\": \"A\", \"escape\": -0.004708772794066627, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -0.0969, \"times_seen\": 2.0}, {\"site\": 593, \"mutant\": \"C\", \"escape\": -0.007984225917290191, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -1.042, \"times_seen\": 7.0}, {\"site\": 593, \"mutant\": \"F\", \"escape\": -0.011439999332425094, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -0.651, \"times_seen\": 3.0}, {\"site\": 593, \"mutant\": \"I\", \"escape\": -0.009894975375937948, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -2.2683, \"times_seen\": 3.0}, {\"site\": 593, \"mutant\": \"N\", \"escape\": -0.0130741027226399, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -0.941, \"times_seen\": 4.0}, {\"site\": 593, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -2.9489, \"times_seen\": null}, {\"site\": 593, \"mutant\": \"R\", \"escape\": -0.0040914874207627116, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -1.3007, \"times_seen\": 4.0}, {\"site\": 593, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 593, \"mutant\": \"T\", \"escape\": -0.005952603446242046, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 593, \"mutant\": \"Y\", \"escape\": -0.02607717458733937, \"epitope\": \"epitope 1\", \"reference_site\": \"596\", \"functional effect\": -1.4555, \"times_seen\": 2.0}, {\"site\": 594, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 594, \"mutant\": \"A\", \"escape\": -0.002887931318908125, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -1.6931, \"times_seen\": 2.0}, {\"site\": 594, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -3.0615, \"times_seen\": null}, {\"site\": 594, \"mutant\": \"I\", \"escape\": 0.03059414137027565, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -0.7923, \"times_seen\": 7.0}, {\"site\": 594, \"mutant\": \"L\", \"escape\": -0.0029184865412465915, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -1.8609, \"times_seen\": 1.0}, {\"site\": 594, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": -2.8088, \"times_seen\": null}, {\"site\": 594, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"597\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"L\", \"escape\": -0.004440018286463688, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -1.5147, \"times_seen\": 1.0}, {\"site\": 595, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -3.2609, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"T\", \"escape\": -0.003009243432701073, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -2.1948, \"times_seen\": 1.0}, {\"site\": 595, \"mutant\": \"V\", \"escape\": -0.006569983726502544, \"epitope\": \"epitope 1\", \"reference_site\": \"598\", \"functional effect\": -0.7859, \"times_seen\": 17.0}, {\"site\": 596, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 596, \"mutant\": \"A\", \"escape\": -0.006319412593041114, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.4833, \"times_seen\": 2.0}, {\"site\": 596, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.6075, \"times_seen\": null}, {\"site\": 596, \"mutant\": \"I\", \"escape\": -0.04858134781611746, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -1.9985, \"times_seen\": 11.0}, {\"site\": 596, \"mutant\": \"K\", \"escape\": -0.003529003218211298, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.6961, \"times_seen\": 1.0}, {\"site\": 596, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 596, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"599\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"A\", \"escape\": 0.018098222669022546, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": 0.3906, \"times_seen\": 2.0}, {\"site\": 597, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -3.0462, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"L\", \"escape\": -0.011073441092025802, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.586, \"times_seen\": 5.0}, {\"site\": 597, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.9775, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"S\", \"escape\": -0.006519306177994224, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.9757, \"times_seen\": 2.0}, {\"site\": 597, \"mutant\": \"T\", \"escape\": -0.0031655968105085476, \"epitope\": \"epitope 1\", \"reference_site\": \"600\", \"functional effect\": -2.8966, \"times_seen\": 1.0}, {\"site\": 598, \"mutant\": \"C\", \"escape\": 0.001494815298085739, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -2.6823, \"times_seen\": 1.0}, {\"site\": 598, \"mutant\": \"D\", \"escape\": -0.011739154599248697, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -3.0564, \"times_seen\": 4.0}, {\"site\": 598, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 598, \"mutant\": \"H\", \"escape\": -0.002959468949838147, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -2.9556, \"times_seen\": 1.0}, {\"site\": 598, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -3.237, \"times_seen\": null}, {\"site\": 598, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"601\", \"functional effect\": -2.1284, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -2.3607, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -1.7296, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"I\", \"escape\": -0.008299146275431138, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -1.4786, \"times_seen\": 1.0}, {\"site\": 599, \"mutant\": \"L\", \"escape\": -0.003752044189619139, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -2.3935, \"times_seen\": 1.0}, {\"site\": 599, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -3.0817, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"S\", \"escape\": -0.0036671883022918674, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": -0.1275, \"times_seen\": 1.0}, {\"site\": 599, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"602\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 600, \"mutant\": \"D\", \"escape\": -0.008874165144452266, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.1276, \"times_seen\": 8.0}, {\"site\": 600, \"mutant\": \"H\", \"escape\": 0.0015341762258694314, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.5201, \"times_seen\": 9.0}, {\"site\": 600, \"mutant\": \"I\", \"escape\": -0.013337840234411943, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.5396, \"times_seen\": 6.0}, {\"site\": 600, \"mutant\": \"K\", \"escape\": -0.017838226519929213, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.0118, \"times_seen\": 13.0}, {\"site\": 600, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 600, \"mutant\": \"R\", \"escape\": -0.003504067676276404, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": 0.0945, \"times_seen\": 1.0}, {\"site\": 600, \"mutant\": \"S\", \"escape\": 0.049261560275897495, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.2211, \"times_seen\": 19.0}, {\"site\": 600, \"mutant\": \"T\", \"escape\": -0.016152900946249712, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.2757, \"times_seen\": 20.0}, {\"site\": 600, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"603\", \"functional effect\": -0.8372, \"times_seen\": null}, {\"site\": 601, \"mutant\": \"A\", \"escape\": -0.03208202076505414, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": -0.1977, \"times_seen\": 32.0}, {\"site\": 601, \"mutant\": \"I\", \"escape\": -0.02155533622270474, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": 0.0939, \"times_seen\": 76.0}, {\"site\": 601, \"mutant\": \"N\", \"escape\": -0.027942502849992855, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": -0.4228, \"times_seen\": 44.0}, {\"site\": 601, \"mutant\": \"S\", \"escape\": -0.004436909054468645, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": -0.5434, \"times_seen\": 2.0}, {\"site\": 601, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 601, \"mutant\": \"V\", \"escape\": -0.004357533754481206, \"epitope\": \"epitope 1\", \"reference_site\": \"604\", \"functional effect\": 0.0637, \"times_seen\": 6.0}, {\"site\": 602, \"mutant\": \"A\", \"escape\": -0.00019346755326212853, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -1.6258, \"times_seen\": 8.0}, {\"site\": 602, \"mutant\": \"C\", \"escape\": -0.0032088751871863896, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -1.3301, \"times_seen\": 2.0}, {\"site\": 602, \"mutant\": \"F\", \"escape\": -0.004905328885448716, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -2.9726, \"times_seen\": 1.0}, {\"site\": 602, \"mutant\": \"G\", \"escape\": -0.005132280247736204, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -1.7384, \"times_seen\": 6.0}, {\"site\": 602, \"mutant\": \"I\", \"escape\": -0.004464234854279496, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": 0.1573, \"times_seen\": 1.0}, {\"site\": 602, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -3.1345, \"times_seen\": null}, {\"site\": 602, \"mutant\": \"N\", \"escape\": -0.00651022431266126, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -2.5998, \"times_seen\": 3.0}, {\"site\": 602, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 602, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 602, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"605\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"D\", \"escape\": -0.009783277499740152, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": 0.0398, \"times_seen\": 19.0}, {\"site\": 603, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.133, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"K\", \"escape\": 0.042229181173283406, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.9545, \"times_seen\": 7.0}, {\"site\": 603, \"mutant\": \"L\", \"escape\": -0.002781824597361332, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.7121, \"times_seen\": 1.0}, {\"site\": 603, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"S\", \"escape\": -0.05138332120172761, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.0215, \"times_seen\": 10.0}, {\"site\": 603, \"mutant\": \"T\", \"escape\": 0.002484686670674448, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -0.4306, \"times_seen\": 17.0}, {\"site\": 603, \"mutant\": \"Y\", \"escape\": -0.0035719017038899252, \"epitope\": \"epitope 1\", \"reference_site\": \"606\", \"functional effect\": -1.1502, \"times_seen\": 6.0}, {\"site\": 604, \"mutant\": \"*\", \"escape\": -0.004511983619013342, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -2.9643, \"times_seen\": 1.0}, {\"site\": 604, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.3317, \"times_seen\": null}, {\"site\": 604, \"mutant\": \"H\", \"escape\": -0.04392793410237395, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.374, \"times_seen\": 56.0}, {\"site\": 604, \"mutant\": \"K\", \"escape\": -0.06975422232335285, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.0725, \"times_seen\": 54.0}, {\"site\": 604, \"mutant\": \"L\", \"escape\": -0.018240731847269587, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.1144, \"times_seen\": 16.0}, {\"site\": 604, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 604, \"mutant\": \"R\", \"escape\": 0.004742498318789127, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": -0.2201, \"times_seen\": 38.0}, {\"site\": 604, \"mutant\": \"V\", \"escape\": -0.05447263994239273, \"epitope\": \"epitope 1\", \"reference_site\": \"607\", \"functional effect\": 0.0911, \"times_seen\": 15.0}, {\"site\": 605, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -1.4881, \"times_seen\": null}, {\"site\": 605, \"mutant\": \"D\", \"escape\": -0.005747385717437663, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -0.6953, \"times_seen\": 2.0}, {\"site\": 605, \"mutant\": \"F\", \"escape\": -0.006481305374097448, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -0.2404, \"times_seen\": 7.0}, {\"site\": 605, \"mutant\": \"I\", \"escape\": 0.02025093691910072, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -0.1307, \"times_seen\": 20.0}, {\"site\": 605, \"mutant\": \"L\", \"escape\": 0.01831200629192198, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 605, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": -2.9968, \"times_seen\": null}, {\"site\": 605, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"608\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.843, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.0465, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"S\", \"escape\": -0.08752953393516237, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.4976, \"times_seen\": 7.0}, {\"site\": 606, \"mutant\": \"T\", \"escape\": -0.003108233178145212, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.2921, \"times_seen\": 2.0}, {\"site\": 606, \"mutant\": \"V\", \"escape\": -0.001011627906404836, \"epitope\": \"epitope 1\", \"reference_site\": \"609\", \"functional effect\": -2.7193, \"times_seen\": 5.0}, {\"site\": 607, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -3.0487, \"times_seen\": null}, {\"site\": 607, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -3.2443, \"times_seen\": null}, {\"site\": 607, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -2.9958, \"times_seen\": null}, {\"site\": 607, \"mutant\": \"I\", \"escape\": -0.005597745777350122, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -0.3049, \"times_seen\": 3.0}, {\"site\": 607, \"mutant\": \"L\", \"escape\": -0.01132443358338183, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -1.1414, \"times_seen\": 12.0}, {\"site\": 607, \"mutant\": \"M\", \"escape\": 0.017432196024956857, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": -2.8599, \"times_seen\": 1.0}, {\"site\": 607, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"610\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 608, \"mutant\": \"F\", \"escape\": 0.5892022725451884, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -0.9023, \"times_seen\": 84.0}, {\"site\": 608, \"mutant\": \"I\", \"escape\": -0.008829543630817236, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -1.4612, \"times_seen\": 4.0}, {\"site\": 608, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 608, \"mutant\": \"P\", \"escape\": 0.004313753288785044, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -2.9813, \"times_seen\": 1.0}, {\"site\": 608, \"mutant\": \"V\", \"escape\": 0.00020253577545201412, \"epitope\": \"epitope 1\", \"reference_site\": \"611\", \"functional effect\": -1.9878, \"times_seen\": 2.0}, {\"site\": 609, \"mutant\": \"*\", \"escape\": -0.003722406232756611, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9522, \"times_seen\": 1.0}, {\"site\": 609, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9547, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"F\", \"escape\": -0.00012685075117085438, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -0.6197, \"times_seen\": 6.0}, {\"site\": 609, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.7929, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9456, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": -2.9307, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"612\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 610, \"mutant\": \"*\", \"escape\": -0.016121708254090317, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -2.5233, \"times_seen\": 1.0}, {\"site\": 610, \"mutant\": \"E\", \"escape\": 0.03525487860166492, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -0.0633, \"times_seen\": 17.0}, {\"site\": 610, \"mutant\": \"H\", \"escape\": 0.006286056450399751, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": 0.0786, \"times_seen\": 18.0}, {\"site\": 610, \"mutant\": \"K\", \"escape\": -0.028711834761722416, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -1.4795, \"times_seen\": 11.0}, {\"site\": 610, \"mutant\": \"L\", \"escape\": -0.019057469401726285, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -1.6206, \"times_seen\": 5.0}, {\"site\": 610, \"mutant\": \"P\", \"escape\": 0.009253321842735002, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -1.1987, \"times_seen\": 2.0}, {\"site\": 610, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 610, \"mutant\": \"R\", \"escape\": -0.9709318136322448, \"epitope\": \"epitope 1\", \"reference_site\": \"613\", \"functional effect\": -0.1161, \"times_seen\": 60.0}, {\"site\": 611, \"mutant\": \"*\", \"escape\": -0.0038935654739980837, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.5617, \"times_seen\": 1.0}, {\"site\": 611, \"mutant\": \"A\", \"escape\": -0.007092418780406389, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.7202, \"times_seen\": 18.0}, {\"site\": 611, \"mutant\": \"C\", \"escape\": -0.009384699905781797, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.8353, \"times_seen\": 2.0}, {\"site\": 611, \"mutant\": \"D\", \"escape\": -0.7587912570264378, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.1259, \"times_seen\": 15.0}, {\"site\": 611, \"mutant\": \"E\", \"escape\": -0.005939352846054138, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.4898, \"times_seen\": 3.0}, {\"site\": 611, \"mutant\": \"F\", \"escape\": 0.05677290308611788, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -3.0182, \"times_seen\": 2.0}, {\"site\": 611, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 611, \"mutant\": \"H\", \"escape\": -0.007623217882543046, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.6028, \"times_seen\": 2.0}, {\"site\": 611, \"mutant\": \"I\", \"escape\": -0.04037550923927001, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.8835, \"times_seen\": 1.0}, {\"site\": 611, \"mutant\": \"K\", \"escape\": -0.012220514514753282, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.5818, \"times_seen\": 6.0}, {\"site\": 611, \"mutant\": \"L\", \"escape\": 0.9088145613910393, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.0809, \"times_seen\": 10.0}, {\"site\": 611, \"mutant\": \"M\", \"escape\": -0.006907946794522087, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.0646, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"N\", \"escape\": -2.7544566320371957, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": 0.1571, \"times_seen\": 11.0}, {\"site\": 611, \"mutant\": \"P\", \"escape\": -0.000933487551384198, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -3.008, \"times_seen\": 1.0}, {\"site\": 611, \"mutant\": \"Q\", \"escape\": 0.0030478121271150854, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.9781, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"R\", \"escape\": 1.1577519595043169, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.5402, \"times_seen\": 21.0}, {\"site\": 611, \"mutant\": \"S\", \"escape\": 0.20569732444865768, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -0.612, \"times_seen\": 38.0}, {\"site\": 611, \"mutant\": \"T\", \"escape\": -0.07858171579649766, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -1.6407, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"V\", \"escape\": -0.008989344987822794, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.6495, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"W\", \"escape\": -0.012908116743069064, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.742, \"times_seen\": 5.0}, {\"site\": 611, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"614\", \"functional effect\": -2.8327, \"times_seen\": null}, {\"site\": 612, \"mutant\": \"A\", \"escape\": 0.02847052922438182, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -0.5794, \"times_seen\": 13.0}, {\"site\": 612, \"mutant\": \"E\", \"escape\": -0.004119426989292439, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 612, \"mutant\": \"F\", \"escape\": -0.0017212313652098924, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -1.6823, \"times_seen\": 6.0}, {\"site\": 612, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 612, \"mutant\": \"I\", \"escape\": 0.015474779023969145, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": 0.0285, \"times_seen\": 15.0}, {\"site\": 612, \"mutant\": \"L\", \"escape\": 0.013639974616253185, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -0.5605, \"times_seen\": 8.0}, {\"site\": 612, \"mutant\": \"M\", \"escape\": -0.007391057760801345, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": -0.132, \"times_seen\": 26.0}, {\"site\": 612, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"615\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 613, \"mutant\": \"D\", \"escape\": -0.013731145462860845, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": -0.0954, \"times_seen\": 12.0}, {\"site\": 613, \"mutant\": \"K\", \"escape\": 0.07104626127997597, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.045, \"times_seen\": 50.0}, {\"site\": 613, \"mutant\": \"L\", \"escape\": -0.008405366811322432, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.2989, \"times_seen\": 4.0}, {\"site\": 613, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 613, \"mutant\": \"S\", \"escape\": 0.014166306082791017, \"epitope\": \"epitope 1\", \"reference_site\": \"616\", \"functional effect\": 0.0998, \"times_seen\": 9.0}, {\"site\": 614, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.8497, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.5949, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"L\", \"escape\": -0.0019474585225941682, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.5849, \"times_seen\": 1.0}, {\"site\": 614, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -1.2614, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -3.132, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"Y\", \"escape\": 0.018657882619184184, \"epitope\": \"epitope 1\", \"reference_site\": \"617\", \"functional effect\": -2.6836, \"times_seen\": 2.0}, {\"site\": 615, \"mutant\": \"A\", \"escape\": -0.017552995393230447, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.2089, \"times_seen\": 30.0}, {\"site\": 615, \"mutant\": \"I\", \"escape\": -0.4848517593621588, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": -0.0548, \"times_seen\": 30.0}, {\"site\": 615, \"mutant\": \"K\", \"escape\": 0.03093647616130946, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.2881, \"times_seen\": 13.0}, {\"site\": 615, \"mutant\": \"N\", \"escape\": 0.04588801865102217, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.3502, \"times_seen\": 6.0}, {\"site\": 615, \"mutant\": \"R\", \"escape\": 0.0012542101702986443, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": -0.3306, \"times_seen\": 10.0}, {\"site\": 615, \"mutant\": \"S\", \"escape\": 0.01153644484307663, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": -0.0955, \"times_seen\": 8.0}, {\"site\": 615, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"618\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 616, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -1.4132, \"times_seen\": null}, {\"site\": 616, \"mutant\": \"A\", \"escape\": 0.03602100173897529, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.506, \"times_seen\": 6.0}, {\"site\": 616, \"mutant\": \"D\", \"escape\": 0.018605464740242144, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.3661, \"times_seen\": 28.0}, {\"site\": 616, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 616, \"mutant\": \"G\", \"escape\": 0.003499482710224639, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -1.2736, \"times_seen\": 19.0}, {\"site\": 616, \"mutant\": \"K\", \"escape\": 0.3752910183406086, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.7037, \"times_seen\": 39.0}, {\"site\": 616, \"mutant\": \"Q\", \"escape\": 0.06694689153548462, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.3618, \"times_seen\": 15.0}, {\"site\": 616, \"mutant\": \"R\", \"escape\": 0.011644673538550756, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -0.6991, \"times_seen\": 4.0}, {\"site\": 616, \"mutant\": \"V\", \"escape\": -0.03722776004619193, \"epitope\": \"epitope 1\", \"reference_site\": \"619\", \"functional effect\": -1.0595, \"times_seen\": 10.0}, {\"site\": 617, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 617, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -2.1861, \"times_seen\": null}, {\"site\": 617, \"mutant\": \"F\", \"escape\": -0.006492134966503707, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -2.9745, \"times_seen\": 2.0}, {\"site\": 617, \"mutant\": \"I\", \"escape\": -0.005440044140962385, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -1.8411, \"times_seen\": 2.0}, {\"site\": 617, \"mutant\": \"L\", \"escape\": 0.0021328999675639033, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -1.49, \"times_seen\": 7.0}, {\"site\": 617, \"mutant\": \"M\", \"escape\": -0.016808306473516738, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": -1.9799, \"times_seen\": 4.0}, {\"site\": 617, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"620\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"A\", \"escape\": -0.008379445339972544, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": 0.2404, \"times_seen\": 2.0}, {\"site\": 618, \"mutant\": \"G\", \"escape\": -0.009423732980799624, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.185, \"times_seen\": 1.0}, {\"site\": 618, \"mutant\": \"H\", \"escape\": -0.06391600699425892, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.2754, \"times_seen\": 13.0}, {\"site\": 618, \"mutant\": \"L\", \"escape\": -1.1478762785427414, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -1.4398, \"times_seen\": 9.0}, {\"site\": 618, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.3843, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"R\", \"escape\": -0.015155378495029506, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.8676, \"times_seen\": 2.0}, {\"site\": 618, \"mutant\": \"S\", \"escape\": 0.02608003049618771, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": 0.0839, \"times_seen\": 21.0}, {\"site\": 618, \"mutant\": \"T\", \"escape\": -0.028392086026398373, \"epitope\": \"epitope 1\", \"reference_site\": \"621\", \"functional effect\": -0.8725, \"times_seen\": 11.0}, {\"site\": 619, \"mutant\": \"*\", \"escape\": -0.0026195778511085965, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -2.9006, \"times_seen\": 1.0}, {\"site\": 619, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -2.2694, \"times_seen\": null}, {\"site\": 619, \"mutant\": \"A\", \"escape\": 0.09988358437132415, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.2054, \"times_seen\": 74.0}, {\"site\": 619, \"mutant\": \"C\", \"escape\": -0.053288623078875004, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.7004, \"times_seen\": 16.0}, {\"site\": 619, \"mutant\": \"D\", \"escape\": -0.040436978015329736, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.1215, \"times_seen\": 25.0}, {\"site\": 619, \"mutant\": \"E\", \"escape\": -0.04750492761464948, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0828, \"times_seen\": 46.0}, {\"site\": 619, \"mutant\": \"F\", \"escape\": 0.49705410780433995, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0222, \"times_seen\": 48.0}, {\"site\": 619, \"mutant\": \"G\", \"escape\": -0.3786504902712539, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.3922, \"times_seen\": 90.0}, {\"site\": 619, \"mutant\": \"H\", \"escape\": 0.000592128707918666, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0315, \"times_seen\": 9.0}, {\"site\": 619, \"mutant\": \"I\", \"escape\": -0.033722149436960426, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0573, \"times_seen\": 17.0}, {\"site\": 619, \"mutant\": \"K\", \"escape\": 0.005924799950205199, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.264, \"times_seen\": 19.0}, {\"site\": 619, \"mutant\": \"L\", \"escape\": 0.1981964570256221, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0054, \"times_seen\": 110.0}, {\"site\": 619, \"mutant\": \"M\", \"escape\": -0.05547303430603292, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0884, \"times_seen\": 33.0}, {\"site\": 619, \"mutant\": \"N\", \"escape\": 0.023272754704381466, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.078, \"times_seen\": 19.0}, {\"site\": 619, \"mutant\": \"P\", \"escape\": -0.000746342185902598, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.457, \"times_seen\": 24.0}, {\"site\": 619, \"mutant\": \"Q\", \"escape\": -0.0029280332968044604, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0915, \"times_seen\": 20.0}, {\"site\": 619, \"mutant\": \"R\", \"escape\": -1.225781250795315, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.3886, \"times_seen\": 66.0}, {\"site\": 619, \"mutant\": \"S\", \"escape\": -0.08707916125499233, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.1195, \"times_seen\": 47.0}, {\"site\": 619, \"mutant\": \"T\", \"escape\": -0.007070143055570529, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0777, \"times_seen\": 22.0}, {\"site\": 619, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 619, \"mutant\": \"W\", \"escape\": 0.047981852202589485, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0497, \"times_seen\": 19.0}, {\"site\": 619, \"mutant\": \"Y\", \"escape\": -0.20270871945820285, \"epitope\": \"epitope 1\", \"reference_site\": \"622\", \"functional effect\": -0.0704, \"times_seen\": 15.0}, {\"site\": 620, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -1.736, \"times_seen\": null}, {\"site\": 620, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 620, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -1.2151, \"times_seen\": null}, {\"site\": 620, \"mutant\": \"L\", \"escape\": -0.007195454588672833, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": 0.2509, \"times_seen\": 2.0}, {\"site\": 620, \"mutant\": \"S\", \"escape\": -0.07329250095262502, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -0.1413, \"times_seen\": 17.0}, {\"site\": 620, \"mutant\": \"T\", \"escape\": 0.005456596506786592, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -0.205, \"times_seen\": 43.0}, {\"site\": 620, \"mutant\": \"V\", \"escape\": 0.020556752389463508, \"epitope\": \"epitope 1\", \"reference_site\": \"623\", \"functional effect\": -0.3156, \"times_seen\": 48.0}, {\"site\": 621, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 621, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 621, \"mutant\": \"L\", \"escape\": 0.0043209290525947925, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.197, \"times_seen\": 1.0}, {\"site\": 621, \"mutant\": \"M\", \"escape\": -0.006285362922846937, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": 0.3237, \"times_seen\": 3.0}, {\"site\": 621, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": -2.6612, \"times_seen\": null}, {\"site\": 621, \"mutant\": \"T\", \"escape\": -0.0007892637655232358, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": -1.5897, \"times_seen\": 6.0}, {\"site\": 621, \"mutant\": \"V\", \"escape\": -0.016957626065275504, \"epitope\": \"epitope 1\", \"reference_site\": \"624\", \"functional effect\": -0.3589, \"times_seen\": 14.0}, {\"site\": 622, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 622, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 622, \"mutant\": \"L\", \"escape\": -0.06985011597773139, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": -0.6508, \"times_seen\": 5.0}, {\"site\": 622, \"mutant\": \"N\", \"escape\": -0.0027748756572570418, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.0723, \"times_seen\": 10.0}, {\"site\": 622, \"mutant\": \"Q\", \"escape\": 0.018008228997171607, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": -0.2539, \"times_seen\": 6.0}, {\"site\": 622, \"mutant\": \"R\", \"escape\": -0.03079210119545898, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": 0.3651, \"times_seen\": 27.0}, {\"site\": 622, \"mutant\": \"Y\", \"escape\": -0.03308570221093113, \"epitope\": \"epitope 1\", \"reference_site\": \"625\", \"functional effect\": -1.0128, \"times_seen\": 9.0}, {\"site\": 623, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 623, \"mutant\": \"D\", \"escape\": -0.01655902143370427, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.1853, \"times_seen\": 5.0}, {\"site\": 623, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 623, \"mutant\": \"P\", \"escape\": 0.015998057738374743, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -2.37, \"times_seen\": 1.0}, {\"site\": 623, \"mutant\": \"Q\", \"escape\": 0.06252186376909044, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.8131, \"times_seen\": 6.0}, {\"site\": 623, \"mutant\": \"R\", \"escape\": -0.004714529105948148, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -1.9877, \"times_seen\": 5.0}, {\"site\": 623, \"mutant\": \"S\", \"escape\": 0.0015723348437004243, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": 0.0731, \"times_seen\": 20.0}, {\"site\": 623, \"mutant\": \"T\", \"escape\": -0.014154941314566, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.301, \"times_seen\": 33.0}, {\"site\": 623, \"mutant\": \"V\", \"escape\": -0.08256547644759887, \"epitope\": \"epitope 1\", \"reference_site\": \"626\", \"functional effect\": -0.1941, \"times_seen\": 52.0}, {\"site\": 624, \"mutant\": \"A\", \"escape\": 0.09854840497949767, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.0542, \"times_seen\": 8.0}, {\"site\": 624, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 624, \"mutant\": \"E\", \"escape\": 0.05435856049209559, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": 0.2853, \"times_seen\": 32.0}, {\"site\": 624, \"mutant\": \"G\", \"escape\": 0.028033619908867102, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.3528, \"times_seen\": 29.0}, {\"site\": 624, \"mutant\": \"H\", \"escape\": 0.14260647249741912, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 624, \"mutant\": \"N\", \"escape\": 0.005756354922464424, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -0.1129, \"times_seen\": 25.0}, {\"site\": 624, \"mutant\": \"S\", \"escape\": 0.00027082767004492304, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": 0.3301, \"times_seen\": 1.0}, {\"site\": 624, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -1.7134, \"times_seen\": null}, {\"site\": 624, \"mutant\": \"Y\", \"escape\": 0.001599222016865987, \"epitope\": \"epitope 1\", \"reference_site\": \"627\", \"functional effect\": -1.169, \"times_seen\": 23.0}, {\"site\": 625, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -1.9116, \"times_seen\": null}, {\"site\": 625, \"mutant\": \"E\", \"escape\": 0.010253797692490121, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -0.1243, \"times_seen\": 4.0}, {\"site\": 625, \"mutant\": \"H\", \"escape\": -0.001178776002639158, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -1.7745, \"times_seen\": 1.0}, {\"site\": 625, \"mutant\": \"K\", \"escape\": 0.05505686834193146, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": 0.3651, \"times_seen\": 24.0}, {\"site\": 625, \"mutant\": \"L\", \"escape\": -0.047662482083265977, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -0.5072, \"times_seen\": 30.0}, {\"site\": 625, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -2.8236, \"times_seen\": null}, {\"site\": 625, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 625, \"mutant\": \"R\", \"escape\": 0.03162882317210861, \"epitope\": \"epitope 1\", \"reference_site\": \"628\", \"functional effect\": -0.0393, \"times_seen\": 4.0}, {\"site\": 626, \"mutant\": \"C\", \"escape\": -0.003931571147837488, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": 0.2464, \"times_seen\": 1.0}, {\"site\": 626, \"mutant\": \"F\", \"escape\": -0.006617720373523643, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -2.3288, \"times_seen\": 3.0}, {\"site\": 626, \"mutant\": \"H\", \"escape\": -0.00745665458478662, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -2.041, \"times_seen\": 2.0}, {\"site\": 626, \"mutant\": \"I\", \"escape\": -0.02597142746517162, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -0.1729, \"times_seen\": 6.0}, {\"site\": 626, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 626, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 626, \"mutant\": \"V\", \"escape\": 0.007663024725468586, \"epitope\": \"epitope 1\", \"reference_site\": \"629\", \"functional effect\": 0.0994, \"times_seen\": 4.0}, {\"site\": 627, \"mutant\": \"A\", \"escape\": 0.002609725630747668, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -0.4191, \"times_seen\": 13.0}, {\"site\": 627, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -2.6515, \"times_seen\": null}, {\"site\": 627, \"mutant\": \"I\", \"escape\": -0.01695397816346723, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -2.566, \"times_seen\": 4.0}, {\"site\": 627, \"mutant\": \"K\", \"escape\": 0.000985500746284859, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -3.0079, \"times_seen\": 1.0}, {\"site\": 627, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -0.6732, \"times_seen\": null}, {\"site\": 627, \"mutant\": \"N\", \"escape\": -0.017237229462376203, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -1.4567, \"times_seen\": 5.0}, {\"site\": 627, \"mutant\": \"S\", \"escape\": 0.0019710450023928687, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": -0.2781, \"times_seen\": 6.0}, {\"site\": 627, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"630\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 628, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -2.5612, \"times_seen\": null}, {\"site\": 628, \"mutant\": \"H\", \"escape\": -0.03731273166062355, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.7566, \"times_seen\": 6.0}, {\"site\": 628, \"mutant\": \"L\", \"escape\": -0.029505584050731625, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -1.2904, \"times_seen\": 14.0}, {\"site\": 628, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 628, \"mutant\": \"Q\", \"escape\": 0.008200882730005759, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.4117, \"times_seen\": 1.0}, {\"site\": 628, \"mutant\": \"S\", \"escape\": -0.027118683048934042, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.6186, \"times_seen\": 17.0}, {\"site\": 628, \"mutant\": \"T\", \"escape\": -0.021783226581600992, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -0.7441, \"times_seen\": 10.0}, {\"site\": 628, \"mutant\": \"Y\", \"escape\": 0.024243951668373998, \"epitope\": \"epitope 1\", \"reference_site\": \"631\", \"functional effect\": -1.4315, \"times_seen\": 3.0}, {\"site\": 629, \"mutant\": \"A\", \"escape\": 0.008387445981491883, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.2457, \"times_seen\": 23.0}, {\"site\": 629, \"mutant\": \"I\", \"escape\": -0.003379292749038787, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.5282, \"times_seen\": 20.0}, {\"site\": 629, \"mutant\": \"N\", \"escape\": -0.014536439980659161, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.2064, \"times_seen\": 46.0}, {\"site\": 629, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": -0.5555, \"times_seen\": null}, {\"site\": 629, \"mutant\": \"S\", \"escape\": 0.013586341728447396, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": 0.0444, \"times_seen\": 3.0}, {\"site\": 629, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"632\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 630, \"mutant\": \"*\", \"escape\": -0.0016279690501822923, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -1.8527, \"times_seen\": 5.0}, {\"site\": 630, \"mutant\": \"C\", \"escape\": -0.004345265818941149, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -3.0486, \"times_seen\": 1.0}, {\"site\": 630, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -3.2461, \"times_seen\": null}, {\"site\": 630, \"mutant\": \"L\", \"escape\": -0.006973991477279943, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -3.1025, \"times_seen\": 1.0}, {\"site\": 630, \"mutant\": \"R\", \"escape\": -0.006822367099883301, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -2.6673, \"times_seen\": 2.0}, {\"site\": 630, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 630, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"633\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 631, \"mutant\": \"G\", \"escape\": -0.015167936445905847, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -1.3895, \"times_seen\": 7.0}, {\"site\": 631, \"mutant\": \"H\", \"escape\": -0.3579646252992568, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.1903, \"times_seen\": 4.0}, {\"site\": 631, \"mutant\": \"K\", \"escape\": -0.026732930730161027, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.1111, \"times_seen\": 10.0}, {\"site\": 631, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.6942, \"times_seen\": null}, {\"site\": 631, \"mutant\": \"M\", \"escape\": 0.0073120065987958005, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.2623, \"times_seen\": 4.0}, {\"site\": 631, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 631, \"mutant\": \"S\", \"escape\": -0.00730486108451849, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -0.679, \"times_seen\": 2.0}, {\"site\": 631, \"mutant\": \"W\", \"escape\": -0.010170036910785078, \"epitope\": \"epitope 1\", \"reference_site\": \"634\", \"functional effect\": -2.2069, \"times_seen\": 1.0}, {\"site\": 632, \"mutant\": \"A\", \"escape\": -0.016236836343290005, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": -0.3495, \"times_seen\": 8.0}, {\"site\": 632, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": -0.0971, \"times_seen\": null}, {\"site\": 632, \"mutant\": \"F\", \"escape\": 0.0004664103216425904, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.0355, \"times_seen\": 33.0}, {\"site\": 632, \"mutant\": \"G\", \"escape\": 0.01752208074638948, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": -0.5959, \"times_seen\": 15.0}, {\"site\": 632, \"mutant\": \"I\", \"escape\": -0.027790829889894744, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.0208, \"times_seen\": 39.0}, {\"site\": 632, \"mutant\": \"L\", \"escape\": 0.006698597861967528, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.1798, \"times_seen\": 4.0}, {\"site\": 632, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"635\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 633, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 633, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -3.0175, \"times_seen\": null}, {\"site\": 633, \"mutant\": \"F\", \"escape\": -0.017239763297000558, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -0.1222, \"times_seen\": 7.0}, {\"site\": 633, \"mutant\": \"H\", \"escape\": -0.02990473626445371, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -0.4859, \"times_seen\": 13.0}, {\"site\": 633, \"mutant\": \"L\", \"escape\": 0.00589301492420359, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -1.1597, \"times_seen\": 2.0}, {\"site\": 633, \"mutant\": \"N\", \"escape\": -0.0038955293902759366, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": -2.7835, \"times_seen\": 1.0}, {\"site\": 633, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"636\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"A\", \"escape\": 0.01986418981680939, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 634, \"mutant\": \"C\", \"escape\": -0.030585256141398398, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -0.3422, \"times_seen\": 14.0}, {\"site\": 634, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -2.2629, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"G\", \"escape\": 0.0020324609169302746, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -1.0914, \"times_seen\": 6.0}, {\"site\": 634, \"mutant\": \"I\", \"escape\": -0.006064459239984825, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.0202, \"times_seen\": 4.0}, {\"site\": 634, \"mutant\": \"N\", \"escape\": -0.00692930857860975, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -2.5185, \"times_seen\": 2.0}, {\"site\": 634, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -3.2586, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": -1.5063, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"637\", \"functional effect\": 0.5058, \"times_seen\": null}, {\"site\": 635, \"mutant\": \"A\", \"escape\": 0.0036857112326138617, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": -0.1178, \"times_seen\": 4.0}, {\"site\": 635, \"mutant\": \"I\", \"escape\": -0.035470372510203615, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": -0.7965, \"times_seen\": 30.0}, {\"site\": 635, \"mutant\": \"K\", \"escape\": -0.05238702784707848, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": 0.0897, \"times_seen\": 14.0}, {\"site\": 635, \"mutant\": \"R\", \"escape\": -0.014440072967992849, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": -0.0527, \"times_seen\": 7.0}, {\"site\": 635, \"mutant\": \"S\", \"escape\": 0.008277205717677816, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": 0.1727, \"times_seen\": 5.0}, {\"site\": 635, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"638\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 636, \"mutant\": \"A\", \"escape\": -0.014466564063870537, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -0.9815, \"times_seen\": 3.0}, {\"site\": 636, \"mutant\": \"C\", \"escape\": -0.009801164803239334, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.863, \"times_seen\": 2.0}, {\"site\": 636, \"mutant\": \"D\", \"escape\": -0.008173444089326048, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -0.9954, \"times_seen\": 16.0}, {\"site\": 636, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 636, \"mutant\": \"R\", \"escape\": -0.006815722568637492, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.3057, \"times_seen\": 1.0}, {\"site\": 636, \"mutant\": \"S\", \"escape\": -1.0688962782007547, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -0.7301, \"times_seen\": 22.0}, {\"site\": 636, \"mutant\": \"V\", \"escape\": -0.005673428596428676, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.3083, \"times_seen\": 3.0}, {\"site\": 636, \"mutant\": \"Y\", \"escape\": -0.0028365524054223437, \"epitope\": \"epitope 1\", \"reference_site\": \"639\", \"functional effect\": -2.4438, \"times_seen\": 1.0}, {\"site\": 637, \"mutant\": \"*\", \"escape\": -0.0027381067189023787, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -2.6987, \"times_seen\": 1.0}, {\"site\": 637, \"mutant\": \"A\", \"escape\": -0.029459782590752933, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0979, \"times_seen\": 27.0}, {\"site\": 637, \"mutant\": \"C\", \"escape\": -0.01262869967641108, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -1.0014, \"times_seen\": 34.0}, {\"site\": 637, \"mutant\": \"D\", \"escape\": -0.04199206137748578, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0859, \"times_seen\": 27.0}, {\"site\": 637, \"mutant\": \"E\", \"escape\": -0.006634340337933522, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.1585, \"times_seen\": 7.0}, {\"site\": 637, \"mutant\": \"F\", \"escape\": -0.010532174009326245, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.5928, \"times_seen\": 33.0}, {\"site\": 637, \"mutant\": \"G\", \"escape\": 0.027590478583801998, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.2261, \"times_seen\": 44.0}, {\"site\": 637, \"mutant\": \"H\", \"escape\": 0.0956364103335614, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0838, \"times_seen\": 16.0}, {\"site\": 637, \"mutant\": \"I\", \"escape\": 0.6951628831307227, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.3659, \"times_seen\": 19.0}, {\"site\": 637, \"mutant\": \"K\", \"escape\": -0.01421657603579249, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0309, \"times_seen\": 11.0}, {\"site\": 637, \"mutant\": \"L\", \"escape\": -0.02618176622547923, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.485, \"times_seen\": 22.0}, {\"site\": 637, \"mutant\": \"M\", \"escape\": -0.0089883824700876, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0281, \"times_seen\": 8.0}, {\"site\": 637, \"mutant\": \"N\", \"escape\": -0.03546758191772672, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.1217, \"times_seen\": 59.0}, {\"site\": 637, \"mutant\": \"P\", \"escape\": -0.5711649231580027, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.7143, \"times_seen\": 41.0}, {\"site\": 637, \"mutant\": \"Q\", \"escape\": 0.015390744641707544, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0478, \"times_seen\": 11.0}, {\"site\": 637, \"mutant\": \"R\", \"escape\": -0.17254242997064725, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.2198, \"times_seen\": 43.0}, {\"site\": 637, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 637, \"mutant\": \"T\", \"escape\": -0.23087650707168508, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0095, \"times_seen\": 27.0}, {\"site\": 637, \"mutant\": \"V\", \"escape\": -0.023744182373248508, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.0794, \"times_seen\": 18.0}, {\"site\": 637, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 637, \"mutant\": \"Y\", \"escape\": -0.047590069761163756, \"epitope\": \"epitope 1\", \"reference_site\": \"640\", \"functional effect\": -0.3701, \"times_seen\": 11.0}, {\"site\": 638, \"mutant\": \"D\", \"escape\": 0.0016412382303851837, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.2823, \"times_seen\": 8.0}, {\"site\": 638, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.6966, \"times_seen\": null}, {\"site\": 638, \"mutant\": \"H\", \"escape\": 0.020805665355605556, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": 0.0799, \"times_seen\": 6.0}, {\"site\": 638, \"mutant\": \"I\", \"escape\": 0.004278784266871499, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.6825, \"times_seen\": 1.0}, {\"site\": 638, \"mutant\": \"K\", \"escape\": -0.0051810595206878175, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.1028, \"times_seen\": 13.0}, {\"site\": 638, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 638, \"mutant\": \"R\", \"escape\": -0.37573209694288723, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.0317, \"times_seen\": 5.0}, {\"site\": 638, \"mutant\": \"S\", \"escape\": 0.10238424952872935, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.065, \"times_seen\": 29.0}, {\"site\": 638, \"mutant\": \"T\", \"escape\": 0.8194863152918083, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": -0.1098, \"times_seen\": 17.0}, {\"site\": 638, \"mutant\": \"Y\", \"escape\": 0.3476019017966964, \"epitope\": \"epitope 1\", \"reference_site\": \"641\", \"functional effect\": 0.2456, \"times_seen\": 8.0}, {\"site\": 639, \"mutant\": \"A\", \"escape\": 0.00323496175757527, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.2545, \"times_seen\": 9.0}, {\"site\": 639, \"mutant\": \"E\", \"escape\": -0.005115260257946597, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.783, \"times_seen\": 2.0}, {\"site\": 639, \"mutant\": \"F\", \"escape\": 0.09634216363909436, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.7632, \"times_seen\": 15.0}, {\"site\": 639, \"mutant\": \"G\", \"escape\": 0.22555319857232822, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.0204, \"times_seen\": 16.0}, {\"site\": 639, \"mutant\": \"I\", \"escape\": -0.01137308737087072, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.2273, \"times_seen\": 20.0}, {\"site\": 639, \"mutant\": \"L\", \"escape\": 0.05192965378962573, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": -0.605, \"times_seen\": 6.0}, {\"site\": 639, \"mutant\": \"M\", \"escape\": -0.04888557291571836, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.1893, \"times_seen\": 13.0}, {\"site\": 639, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.2404, \"times_seen\": null}, {\"site\": 639, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"642\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 640, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 640, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 640, \"mutant\": \"I\", \"escape\": 0.032041339339987755, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -0.1246, \"times_seen\": 10.0}, {\"site\": 640, \"mutant\": \"L\", \"escape\": 0.013373530066238148, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -0.0159, \"times_seen\": 14.0}, {\"site\": 640, \"mutant\": \"S\", \"escape\": -0.005760079767708483, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -2.1946, \"times_seen\": 1.0}, {\"site\": 640, \"mutant\": \"V\", \"escape\": -0.005543524303139827, \"epitope\": \"epitope 1\", \"reference_site\": \"643\", \"functional effect\": -0.1933, \"times_seen\": 3.0}, {\"site\": 641, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -1.2621, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"H\", \"escape\": -0.039551784062737586, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.2035, \"times_seen\": 17.0}, {\"site\": 641, \"mutant\": \"K\", \"escape\": -0.0033307964307394203, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -2.4358, \"times_seen\": 1.0}, {\"site\": 641, \"mutant\": \"L\", \"escape\": -0.016461673338543793, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.7004, \"times_seen\": 10.0}, {\"site\": 641, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -2.1822, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"R\", \"escape\": -0.025590983523563485, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -2.2531, \"times_seen\": 10.0}, {\"site\": 641, \"mutant\": \"S\", \"escape\": -0.003846244779811874, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.2763, \"times_seen\": 1.0}, {\"site\": 641, \"mutant\": \"T\", \"escape\": -0.010355692133331616, \"epitope\": \"epitope 1\", \"reference_site\": \"644\", \"functional effect\": -0.0797, \"times_seen\": 2.0}, {\"site\": 642, \"mutant\": \"A\", \"escape\": -0.0024347270951791153, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.343, \"times_seen\": 1.0}, {\"site\": 642, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.5747, \"times_seen\": null}, {\"site\": 642, \"mutant\": \"I\", \"escape\": -0.015688294625497357, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -1.6248, \"times_seen\": 12.0}, {\"site\": 642, \"mutant\": \"N\", \"escape\": -0.0071249820753191305, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.5189, \"times_seen\": 2.0}, {\"site\": 642, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -0.1741, \"times_seen\": null}, {\"site\": 642, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 642, \"mutant\": \"V\", \"escape\": -0.043309010700975474, \"epitope\": \"epitope 1\", \"reference_site\": \"645\", \"functional effect\": -2.6014, \"times_seen\": 4.0}, {\"site\": 643, \"mutant\": \"G\", \"escape\": 0.011199952952508616, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.2698, \"times_seen\": 17.0}, {\"site\": 643, \"mutant\": \"H\", \"escape\": -0.02510195853413549, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.115, \"times_seen\": 16.0}, {\"site\": 643, \"mutant\": \"K\", \"escape\": 0.00920357479027231, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.1284, \"times_seen\": 8.0}, {\"site\": 643, \"mutant\": \"L\", \"escape\": 0.27630213732918063, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.2324, \"times_seen\": 19.0}, {\"site\": 643, \"mutant\": \"M\", \"escape\": -0.0009437616012273674, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.0412, \"times_seen\": 11.0}, {\"site\": 643, \"mutant\": \"P\", \"escape\": 0.001477170969114051, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.2483, \"times_seen\": 1.0}, {\"site\": 643, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 643, \"mutant\": \"S\", \"escape\": 1.532199967340938, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.1537, \"times_seen\": 12.0}, {\"site\": 643, \"mutant\": \"T\", \"escape\": -0.003107249082557569, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": 0.4244, \"times_seen\": 4.0}, {\"site\": 643, \"mutant\": \"W\", \"escape\": 0.002951206743097908, \"epitope\": \"epitope 1\", \"reference_site\": \"646\", \"functional effect\": -0.8314, \"times_seen\": 1.0}, {\"site\": 644, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 644, \"mutant\": \"C\", \"escape\": 0.0034267281305129962, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -2.0077, \"times_seen\": 4.0}, {\"site\": 644, \"mutant\": \"D\", \"escape\": 0.004249922548512382, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -0.9453, \"times_seen\": 7.0}, {\"site\": 644, \"mutant\": \"S\", \"escape\": -0.007096522676924758, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -1.0248, \"times_seen\": 17.0}, {\"site\": 644, \"mutant\": \"T\", \"escape\": -0.036322325884677174, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -1.1521, \"times_seen\": 23.0}, {\"site\": 644, \"mutant\": \"V\", \"escape\": -1.3261350044100029, \"epitope\": \"epitope 1\", \"reference_site\": \"647\", \"functional effect\": -0.6934, \"times_seen\": 34.0}, {\"site\": 645, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -3.2615, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"C\", \"escape\": -0.002758827463841607, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -3.0583, \"times_seen\": 1.0}, {\"site\": 645, \"mutant\": \"D\", \"escape\": 0.027715971676644028, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.6399, \"times_seen\": 7.0}, {\"site\": 645, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -3.1376, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.739, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"S\", \"escape\": -0.002634932636366024, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.8237, \"times_seen\": 1.0}, {\"site\": 645, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"648\", \"functional effect\": -2.6423, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -3.1327, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.2135, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"G\", \"escape\": 0.0009143238242345906, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.3547, \"times_seen\": 3.0}, {\"site\": 646, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.922, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.479, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.7214, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"649\", \"functional effect\": -2.8815, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.8995, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.5692, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"M\", \"escape\": 0.033437635932255086, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -1.8481, \"times_seen\": 2.0}, {\"site\": 647, \"mutant\": \"N\", \"escape\": -0.0013991510383120492, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.4623, \"times_seen\": 2.0}, {\"site\": 647, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -1.9246, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.9784, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"650\", \"functional effect\": -2.8907, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -1.796, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"M\", \"escape\": 0.013738932002351061, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -1.436, \"times_seen\": 5.0}, {\"site\": 648, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -2.9986, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"T\", \"escape\": -0.0017652624701470973, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -1.2201, \"times_seen\": 1.0}, {\"site\": 648, \"mutant\": \"V\", \"escape\": 0.011532752294217954, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": 0.0312, \"times_seen\": 16.0}, {\"site\": 648, \"mutant\": \"Y\", \"escape\": -0.007120499683844148, \"epitope\": \"epitope 1\", \"reference_site\": \"651\", \"functional effect\": -2.371, \"times_seen\": 4.0}, {\"site\": 649, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.9974, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.918, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.6322, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"R\", \"escape\": 0.04282811362043204, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -1.3668, \"times_seen\": 5.0}, {\"site\": 649, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -2.8331, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"V\", \"escape\": 0.0193710583353425, \"epitope\": \"epitope 1\", \"reference_site\": \"652\", \"functional effect\": -1.6485, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"*\", \"escape\": -0.01713412470050995, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.8739, \"times_seen\": 4.0}, {\"site\": 650, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 650, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 650, \"mutant\": \"C\", \"escape\": -0.027088156341742865, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.62, \"times_seen\": 9.0}, {\"site\": 650, \"mutant\": \"D\", \"escape\": -0.008842071373407739, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.2756, \"times_seen\": 2.0}, {\"site\": 650, \"mutant\": \"E\", \"escape\": -0.020350802382020552, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"F\", \"escape\": -0.012859385932679226, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.7272, \"times_seen\": 2.0}, {\"site\": 650, \"mutant\": \"G\", \"escape\": -0.0014433355566755722, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.3114, \"times_seen\": 7.0}, {\"site\": 650, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.8205, \"times_seen\": null}, {\"site\": 650, \"mutant\": \"I\", \"escape\": -0.03558071980462587, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.9183, \"times_seen\": 4.0}, {\"site\": 650, \"mutant\": \"K\", \"escape\": -0.010476571845028107, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -3.1279, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"L\", \"escape\": -0.02539532490307956, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.5903, \"times_seen\": 8.0}, {\"site\": 650, \"mutant\": \"M\", \"escape\": -4.249529507261499, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.4428, \"times_seen\": 5.0}, {\"site\": 650, \"mutant\": \"N\", \"escape\": -0.006826088584002297, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -1.5743, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"P\", \"escape\": -0.019536290984445637, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.9389, \"times_seen\": 7.0}, {\"site\": 650, \"mutant\": \"Q\", \"escape\": 0.008391391830413278, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -3.0575, \"times_seen\": 2.0}, {\"site\": 650, \"mutant\": \"R\", \"escape\": -3.1587018791471166, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.5286, \"times_seen\": 11.0}, {\"site\": 650, \"mutant\": \"S\", \"escape\": -0.004843568405476793, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.3997, \"times_seen\": 9.0}, {\"site\": 650, \"mutant\": \"T\", \"escape\": -0.07303567283014845, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.2728, \"times_seen\": 27.0}, {\"site\": 650, \"mutant\": \"V\", \"escape\": 0.032361064294476063, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -0.1762, \"times_seen\": 97.0}, {\"site\": 650, \"mutant\": \"W\", \"escape\": -0.20975802984474334, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.8587, \"times_seen\": 3.0}, {\"site\": 650, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"653\", \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"*\", \"escape\": 0.03448033879660472, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.7878, \"times_seen\": 4.0}, {\"site\": 651, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": 0.1923, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"D\", \"escape\": -0.024670285029605818, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.375, \"times_seen\": 7.0}, {\"site\": 651, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"G\", \"escape\": -0.013629522848673187, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -1.1807, \"times_seen\": 4.0}, {\"site\": 651, \"mutant\": \"K\", \"escape\": -0.002391519425522703, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0612, \"times_seen\": 49.0}, {\"site\": 651, \"mutant\": \"Q\", \"escape\": -0.036750643890103275, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0988, \"times_seen\": 16.0}, {\"site\": 651, \"mutant\": \"R\", \"escape\": 0.006510865804944752, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0751, \"times_seen\": 7.0}, {\"site\": 651, \"mutant\": \"T\", \"escape\": 0.0010743791326448188, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": 0.1148, \"times_seen\": 5.0}, {\"site\": 651, \"mutant\": \"V\", \"escape\": 0.00011445509176043656, \"epitope\": \"epitope 1\", \"reference_site\": \"654\", \"functional effect\": -0.0384, \"times_seen\": 26.0}, {\"site\": 652, \"mutant\": \"*\", \"escape\": 0.0038806784394896927, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.7181, \"times_seen\": 6.0}, {\"site\": 652, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 652, \"mutant\": \"A\", \"escape\": -0.0390879607836629, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.7225, \"times_seen\": 23.0}, {\"site\": 652, \"mutant\": \"C\", \"escape\": -0.0015589871670432095, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.9318, \"times_seen\": 1.0}, {\"site\": 652, \"mutant\": \"D\", \"escape\": -0.01387774454970338, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.3138, \"times_seen\": 3.0}, {\"site\": 652, \"mutant\": \"E\", \"escape\": 0.018520626667846016, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.9528, \"times_seen\": 1.0}, {\"site\": 652, \"mutant\": \"F\", \"escape\": -0.002861086225153432, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -0.1608, \"times_seen\": 15.0}, {\"site\": 652, \"mutant\": \"G\", \"escape\": 0.03288190299836282, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.9483, \"times_seen\": 5.0}, {\"site\": 652, \"mutant\": \"H\", \"escape\": -0.008760161743614237, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -0.9786, \"times_seen\": 25.0}, {\"site\": 652, \"mutant\": \"I\", \"escape\": -0.021277530068707574, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.8491, \"times_seen\": 7.0}, {\"site\": 652, \"mutant\": \"K\", \"escape\": 0.006782435202641757, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.7056, \"times_seen\": 7.0}, {\"site\": 652, \"mutant\": \"L\", \"escape\": -0.06606120399291039, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.0489, \"times_seen\": 17.0}, {\"site\": 652, \"mutant\": \"M\", \"escape\": -0.0440626765577819, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.0462, \"times_seen\": 16.0}, {\"site\": 652, \"mutant\": \"N\", \"escape\": -0.17721937050766745, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.8558, \"times_seen\": 6.0}, {\"site\": 652, \"mutant\": \"P\", \"escape\": -0.14262530928501346, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.6151, \"times_seen\": 12.0}, {\"site\": 652, \"mutant\": \"Q\", \"escape\": -0.012791133824993922, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.7885, \"times_seen\": 5.0}, {\"site\": 652, \"mutant\": \"R\", \"escape\": -0.023653585696505882, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.6506, \"times_seen\": 25.0}, {\"site\": 652, \"mutant\": \"S\", \"escape\": -0.025028395652509142, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.3491, \"times_seen\": 12.0}, {\"site\": 652, \"mutant\": \"T\", \"escape\": 0.021657363809025346, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -2.4896, \"times_seen\": 5.0}, {\"site\": 652, \"mutant\": \"V\", \"escape\": -0.0963676795186514, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -1.3823, \"times_seen\": 18.0}, {\"site\": 652, \"mutant\": \"W\", \"escape\": 0.023747255904489548, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": -0.2047, \"times_seen\": 17.0}, {\"site\": 652, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"655\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 653, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 653, \"mutant\": \"A\", \"escape\": 0.009107269810350224, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -1.2286, \"times_seen\": 7.0}, {\"site\": 653, \"mutant\": \"I\", \"escape\": -0.019476895851820566, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -0.6411, \"times_seen\": 10.0}, {\"site\": 653, \"mutant\": \"L\", \"escape\": 0.02104857876702076, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -0.8782, \"times_seen\": 9.0}, {\"site\": 653, \"mutant\": \"M\", \"escape\": 0.004647284841980538, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -1.2335, \"times_seen\": 19.0}, {\"site\": 653, \"mutant\": \"T\", \"escape\": 0.02001304982981627, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": -0.3178, \"times_seen\": 6.0}, {\"site\": 653, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"656\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"D\", \"escape\": -0.03443131410052694, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": 0.0139, \"times_seen\": 40.0}, {\"site\": 654, \"mutant\": \"H\", \"escape\": -0.018531573282144814, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": 0.0081, \"times_seen\": 8.0}, {\"site\": 654, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.8364, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"K\", \"escape\": 0.006773863787004184, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.2966, \"times_seen\": 12.0}, {\"site\": 654, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"S\", \"escape\": -0.006727793060972859, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.2064, \"times_seen\": 11.0}, {\"site\": 654, \"mutant\": \"T\", \"escape\": -0.04258502158523475, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.0316, \"times_seen\": 13.0}, {\"site\": 654, \"mutant\": \"Y\", \"escape\": -0.4194668840607556, \"epitope\": \"epitope 1\", \"reference_site\": \"657\", \"functional effect\": -0.6074, \"times_seen\": 36.0}, {\"site\": 655, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 655, \"mutant\": \"D\", \"escape\": 0.011565476798289889, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.3327, \"times_seen\": 29.0}, {\"site\": 655, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -0.4271, \"times_seen\": null}, {\"site\": 655, \"mutant\": \"H\", \"escape\": -0.010808714575038233, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.1507, \"times_seen\": 8.0}, {\"site\": 655, \"mutant\": \"I\", \"escape\": 0.011368244614542122, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.1099, \"times_seen\": 3.0}, {\"site\": 655, \"mutant\": \"K\", \"escape\": -0.03763046063562171, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -0.0312, \"times_seen\": 23.0}, {\"site\": 655, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 655, \"mutant\": \"S\", \"escape\": -0.01113494924630676, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.1005, \"times_seen\": 9.0}, {\"site\": 655, \"mutant\": \"T\", \"escape\": 0.7462985107626099, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 655, \"mutant\": \"V\", \"escape\": 0.011778900750385261, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": 0.0244, \"times_seen\": 1.0}, {\"site\": 655, \"mutant\": \"Y\", \"escape\": 0.0001508437305378289, \"epitope\": \"epitope 1\", \"reference_site\": \"658\", \"functional effect\": -0.0921, \"times_seen\": 12.0}, {\"site\": 656, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 656, \"mutant\": \"A\", \"escape\": -0.0031051785789074585, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.6133, \"times_seen\": 5.0}, {\"site\": 656, \"mutant\": \"C\", \"escape\": -0.0035370149017306756, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -1.035, \"times_seen\": 1.0}, {\"site\": 656, \"mutant\": \"F\", \"escape\": -0.020578161528320146, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.6814, \"times_seen\": 3.0}, {\"site\": 656, \"mutant\": \"L\", \"escape\": -0.0280667135525275, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.324, \"times_seen\": 20.0}, {\"site\": 656, \"mutant\": \"P\", \"escape\": -0.02729505466686759, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.881, \"times_seen\": 13.0}, {\"site\": 656, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 656, \"mutant\": \"T\", \"escape\": 0.019761454046211057, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.081, \"times_seen\": 15.0}, {\"site\": 656, \"mutant\": \"Y\", \"escape\": -0.02974308913709992, \"epitope\": \"epitope 1\", \"reference_site\": \"659\", \"functional effect\": -0.666, \"times_seen\": 9.0}, {\"site\": 657, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -1.5896, \"times_seen\": null}, {\"site\": 657, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 657, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.4082, \"times_seen\": null}, {\"site\": 657, \"mutant\": \"F\", \"escape\": 0.08200134216533872, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.0655, \"times_seen\": 17.0}, {\"site\": 657, \"mutant\": \"H\", \"escape\": -0.13642621478410238, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.7964, \"times_seen\": 46.0}, {\"site\": 657, \"mutant\": \"L\", \"escape\": -0.006449070397341047, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -0.0063, \"times_seen\": 7.0}, {\"site\": 657, \"mutant\": \"N\", \"escape\": 0.014638376415749952, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": -1.6674, \"times_seen\": 6.0}, {\"site\": 657, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"660\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -3.087, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"A\", \"escape\": -0.01553202386624932, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.4833, \"times_seen\": 7.0}, {\"site\": 658, \"mutant\": \"D\", \"escape\": 0.8084350424013376, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.2119, \"times_seen\": 32.0}, {\"site\": 658, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"G\", \"escape\": -0.005341997499245968, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.8207, \"times_seen\": 8.0}, {\"site\": 658, \"mutant\": \"K\", \"escape\": 0.015323041532208818, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.2801, \"times_seen\": 10.0}, {\"site\": 658, \"mutant\": \"Q\", \"escape\": 0.033884281578858304, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.1412, \"times_seen\": 5.0}, {\"site\": 658, \"mutant\": \"V\", \"escape\": -0.016782556882549874, \"epitope\": \"epitope 1\", \"reference_site\": \"661\", \"functional effect\": -0.2856, \"times_seen\": 10.0}, {\"site\": 659, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -3.1855, \"times_seen\": null}, {\"site\": 659, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 659, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 659, \"mutant\": \"F\", \"escape\": -0.010524184181521231, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -2.6796, \"times_seen\": 1.0}, {\"site\": 659, \"mutant\": \"R\", \"escape\": -0.008267029254853014, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -2.0399, \"times_seen\": 2.0}, {\"site\": 659, \"mutant\": \"S\", \"escape\": -0.014791664915455624, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -1.9582, \"times_seen\": 1.0}, {\"site\": 659, \"mutant\": \"Y\", \"escape\": -0.005420366373611126, \"epitope\": \"epitope 1\", \"reference_site\": \"662\", \"functional effect\": -2.0971, \"times_seen\": 2.0}, {\"site\": 660, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"E\", \"escape\": -0.01248093241478539, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.0284, \"times_seen\": 4.0}, {\"site\": 660, \"mutant\": \"G\", \"escape\": -0.0063122076521638015, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.1022, \"times_seen\": 3.0}, {\"site\": 660, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -1.7556, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"N\", \"escape\": -0.0007593311848402047, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.0753, \"times_seen\": 1.0}, {\"site\": 660, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -3.125, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"Y\", \"escape\": -0.006911017559057963, \"epitope\": \"epitope 1\", \"reference_site\": \"663\", \"functional effect\": -2.3828, \"times_seen\": 3.0}, {\"site\": 661, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.3552, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"K\", \"escape\": -0.0026163280687687696, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.5567, \"times_seen\": 1.0}, {\"site\": 661, \"mutant\": \"L\", \"escape\": 0.0014325378153881782, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.9382, \"times_seen\": 1.0}, {\"site\": 661, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.2529, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"T\", \"escape\": -0.0027278879553188848, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -2.7824, \"times_seen\": 2.0}, {\"site\": 661, \"mutant\": \"V\", \"escape\": 0.03179211472593001, \"epitope\": \"epitope 1\", \"reference_site\": \"664\", \"functional effect\": -1.5756, \"times_seen\": 3.0}, {\"site\": 662, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 662, \"mutant\": \"A\", \"escape\": 0.006911922049652559, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -0.2973, \"times_seen\": 2.0}, {\"site\": 662, \"mutant\": \"L\", \"escape\": -0.007197046336108175, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -2.3295, \"times_seen\": 2.0}, {\"site\": 662, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 662, \"mutant\": \"Q\", \"escape\": -0.009511123607950771, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -1.8667, \"times_seen\": 3.0}, {\"site\": 662, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -2.1018, \"times_seen\": null}, {\"site\": 662, \"mutant\": \"S\", \"escape\": -0.020301009344681643, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -2.6498, \"times_seen\": 5.0}, {\"site\": 662, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"665\", \"functional effect\": -1.5219, \"times_seen\": null}, {\"site\": 663, \"mutant\": \"F\", \"escape\": 0.0013010137903057034, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 663, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 663, \"mutant\": \"L\", \"escape\": 0.012806277076562067, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -0.8916, \"times_seen\": 3.0}, {\"site\": 663, \"mutant\": \"N\", \"escape\": 0.33451683492140244, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -2.9339, \"times_seen\": 5.0}, {\"site\": 663, \"mutant\": \"S\", \"escape\": 0.002298943854438522, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -2.7603, \"times_seen\": 1.0}, {\"site\": 663, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -2.7785, \"times_seen\": null}, {\"site\": 663, \"mutant\": \"V\", \"escape\": 0.24126830995174783, \"epitope\": \"epitope 1\", \"reference_site\": \"666\", \"functional effect\": -0.2891, \"times_seen\": 24.0}, {\"site\": 664, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -1.7201, \"times_seen\": null}, {\"site\": 664, \"mutant\": \"A\", \"escape\": -0.0033192899062525253, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -0.0997, \"times_seen\": 1.0}, {\"site\": 664, \"mutant\": \"E\", \"escape\": 0.0077564723211352125, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -2.4207, \"times_seen\": 6.0}, {\"site\": 664, \"mutant\": \"F\", \"escape\": -0.01573272155187084, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -1.6171, \"times_seen\": 4.0}, {\"site\": 664, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 664, \"mutant\": \"R\", \"escape\": -0.004091754197167716, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -2.2662, \"times_seen\": 1.0}, {\"site\": 664, \"mutant\": \"S\", \"escape\": -0.00632501361833886, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -0.9965, \"times_seen\": 3.0}, {\"site\": 664, \"mutant\": \"V\", \"escape\": -0.012986583462952788, \"epitope\": \"epitope 1\", \"reference_site\": \"667\", \"functional effect\": -2.5453, \"times_seen\": 3.0}, {\"site\": 665, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 665, \"mutant\": \"E\", \"escape\": -0.011301936986325384, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -0.4449, \"times_seen\": 8.0}, {\"site\": 665, \"mutant\": \"G\", \"escape\": 0.005634982892781956, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": 0.3625, \"times_seen\": 4.0}, {\"site\": 665, \"mutant\": \"S\", \"escape\": 0.001153752590662014, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -0.0976, \"times_seen\": 23.0}, {\"site\": 665, \"mutant\": \"T\", \"escape\": -0.03001314211001785, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -1.6351, \"times_seen\": 10.0}, {\"site\": 665, \"mutant\": \"V\", \"escape\": -0.330888122541632, \"epitope\": \"epitope 1\", \"reference_site\": \"668\", \"functional effect\": -0.9117, \"times_seen\": 45.0}, {\"site\": 666, \"mutant\": \"C\", \"escape\": -0.01071946391780761, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -2.698, \"times_seen\": 1.0}, {\"site\": 666, \"mutant\": \"D\", \"escape\": -0.002905891941425351, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -2.4976, \"times_seen\": 1.0}, {\"site\": 666, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 666, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -0.7519, \"times_seen\": null}, {\"site\": 666, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -3.2764, \"times_seen\": null}, {\"site\": 666, \"mutant\": \"S\", \"escape\": 0.011187743326084085, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -1.2803, \"times_seen\": 8.0}, {\"site\": 666, \"mutant\": \"V\", \"escape\": 0.02161162750636473, \"epitope\": \"epitope 1\", \"reference_site\": \"669\", \"functional effect\": -1.3729, \"times_seen\": 1.0}, {\"site\": 667, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 667, \"mutant\": \"L\", \"escape\": -0.09206012839162081, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": 0.1047, \"times_seen\": 1.0}, {\"site\": 667, \"mutant\": \"M\", \"escape\": 0.02555382619966429, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": -0.9151, \"times_seen\": 13.0}, {\"site\": 667, \"mutant\": \"T\", \"escape\": 0.0005268432868091878, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": -2.6483, \"times_seen\": 1.0}, {\"site\": 667, \"mutant\": \"V\", \"escape\": 0.38932934851075895, \"epitope\": \"epitope 1\", \"reference_site\": \"670\", \"functional effect\": -0.2114, \"times_seen\": 10.0}, {\"site\": 668, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 668, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 668, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.9839, \"times_seen\": null}, {\"site\": 668, \"mutant\": \"G\", \"escape\": -0.00791367799931124, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.8933, \"times_seen\": 1.0}, {\"site\": 668, \"mutant\": \"R\", \"escape\": -0.032188067634557366, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.7944, \"times_seen\": 11.0}, {\"site\": 668, \"mutant\": \"S\", \"escape\": -0.0033518133231273933, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.6835, \"times_seen\": 1.0}, {\"site\": 668, \"mutant\": \"Y\", \"escape\": -0.0025451002422615054, \"epitope\": \"epitope 1\", \"reference_site\": \"671\", \"functional effect\": -2.6498, \"times_seen\": 1.0}, {\"site\": 669, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 669, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 669, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -2.7085, \"times_seen\": null}, {\"site\": 669, \"mutant\": \"S\", \"escape\": 0.0320169020386761, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -2.7888, \"times_seen\": 5.0}, {\"site\": 669, \"mutant\": \"T\", \"escape\": -0.015296356248341013, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -1.3255, \"times_seen\": 19.0}, {\"site\": 669, \"mutant\": \"V\", \"escape\": 0.009417554924045706, \"epitope\": \"epitope 1\", \"reference_site\": \"672\", \"functional effect\": -0.208, \"times_seen\": 58.0}, {\"site\": 670, \"mutant\": \"A\", \"escape\": -0.0031891831611191856, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 670, \"mutant\": \"C\", \"escape\": -0.0014504557270330328, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -1.6065, \"times_seen\": 1.0}, {\"site\": 670, \"mutant\": \"F\", \"escape\": -0.6349589905675418, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.2149, \"times_seen\": 3.0}, {\"site\": 670, \"mutant\": \"G\", \"escape\": 0.01830765518383574, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -0.631, \"times_seen\": 5.0}, {\"site\": 670, \"mutant\": \"I\", \"escape\": -0.018334611929358487, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.7388, \"times_seen\": 6.0}, {\"site\": 670, \"mutant\": \"L\", \"escape\": -0.006411421687877836, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -1.4861, \"times_seen\": 3.0}, {\"site\": 670, \"mutant\": \"P\", \"escape\": -0.013389329120948841, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.4918, \"times_seen\": 4.0}, {\"site\": 670, \"mutant\": \"R\", \"escape\": -0.006682287566723349, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.2607, \"times_seen\": 6.0}, {\"site\": 670, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 670, \"mutant\": \"T\", \"escape\": -0.06548799775314729, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": 0.2622, \"times_seen\": 56.0}, {\"site\": 670, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"673\", \"functional effect\": -2.1489, \"times_seen\": null}, {\"site\": 671, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -2.2944, \"times_seen\": null}, {\"site\": 671, \"mutant\": \"C\", \"escape\": -0.05234865817561422, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -2.3616, \"times_seen\": 2.0}, {\"site\": 671, \"mutant\": \"F\", \"escape\": -0.02298399953137124, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -0.2806, \"times_seen\": 21.0}, {\"site\": 671, \"mutant\": \"H\", \"escape\": -0.7523202370461012, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -1.0209, \"times_seen\": 30.0}, {\"site\": 671, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": -3.0437, \"times_seen\": null}, {\"site\": 671, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"674\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -1.5438, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"-\", \"escape\": -0.0028309456330141212, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.3023, \"times_seen\": 1.0}, {\"site\": 672, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -0.3102, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"H\", \"escape\": 0.01664717873383068, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -0.1829, \"times_seen\": 46.0}, {\"site\": 672, \"mutant\": \"K\", \"escape\": 0.0048739712400759925, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.0557, \"times_seen\": 36.0}, {\"site\": 672, \"mutant\": \"L\", \"escape\": -0.013432812673436633, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.0046, \"times_seen\": 72.0}, {\"site\": 672, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -3.2213, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"N\", \"escape\": 0.0340779109212118, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.2948, \"times_seen\": 9.0}, {\"site\": 672, \"mutant\": \"P\", \"escape\": 0.03892373676837268, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": -0.4375, \"times_seen\": 6.0}, {\"site\": 672, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"R\", \"escape\": -0.04333886938031449, \"epitope\": \"epitope 1\", \"reference_site\": \"675\", \"functional effect\": 0.1768, \"times_seen\": 38.0}, {\"site\": 673, \"mutant\": \"-\", \"escape\": -0.0034519710962079373, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": -0.1647, \"times_seen\": 1.0}, {\"site\": 673, \"mutant\": \"A\", \"escape\": -0.09037128829942055, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": -0.1562, \"times_seen\": 26.0}, {\"site\": 673, \"mutant\": \"I\", \"escape\": -0.025557935568533963, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.1508, \"times_seen\": 34.0}, {\"site\": 673, \"mutant\": \"N\", \"escape\": 0.00454308172642945, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.0301, \"times_seen\": 16.0}, {\"site\": 673, \"mutant\": \"P\", \"escape\": -0.36629904173220906, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.2261, \"times_seen\": 10.0}, {\"site\": 673, \"mutant\": \"R\", \"escape\": -0.007887909529327084, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": -0.4989, \"times_seen\": 1.0}, {\"site\": 673, \"mutant\": \"S\", \"escape\": 0.3737367525171452, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.1098, \"times_seen\": 20.0}, {\"site\": 673, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"676\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 674, \"mutant\": \"*\", \"escape\": -0.01799013458093131, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -2.6388, \"times_seen\": 5.0}, {\"site\": 674, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.2997, \"times_seen\": null}, {\"site\": 674, \"mutant\": \"A\", \"escape\": -0.1144203903220474, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0194, \"times_seen\": 59.0}, {\"site\": 674, \"mutant\": \"C\", \"escape\": 0.035341570998306045, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.3555, \"times_seen\": 12.0}, {\"site\": 674, \"mutant\": \"D\", \"escape\": -0.02556255021875637, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0551, \"times_seen\": 21.0}, {\"site\": 674, \"mutant\": \"E\", \"escape\": -0.0182304423833958, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0269, \"times_seen\": 60.0}, {\"site\": 674, \"mutant\": \"F\", \"escape\": -0.0010776169704543902, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0515, \"times_seen\": 12.0}, {\"site\": 674, \"mutant\": \"G\", \"escape\": 0.0001212145205439233, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0279, \"times_seen\": 73.0}, {\"site\": 674, \"mutant\": \"H\", \"escape\": 0.02043157729946468, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0435, \"times_seen\": 82.0}, {\"site\": 674, \"mutant\": \"I\", \"escape\": 0.02008529646543993, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.4132, \"times_seen\": 18.0}, {\"site\": 674, \"mutant\": \"K\", \"escape\": -0.053774638142298214, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0347, \"times_seen\": 87.0}, {\"site\": 674, \"mutant\": \"L\", \"escape\": -0.02184090434280976, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.115, \"times_seen\": 161.0}, {\"site\": 674, \"mutant\": \"M\", \"escape\": -0.39550965731209387, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.1552, \"times_seen\": 40.0}, {\"site\": 674, \"mutant\": \"N\", \"escape\": 0.008546987296330816, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.1295, \"times_seen\": 22.0}, {\"site\": 674, \"mutant\": \"P\", \"escape\": -0.061401307358141755, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0622, \"times_seen\": 109.0}, {\"site\": 674, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 674, \"mutant\": \"R\", \"escape\": -2.578637147568116, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0838, \"times_seen\": 184.0}, {\"site\": 674, \"mutant\": \"S\", \"escape\": -0.4467700334468363, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": -0.0616, \"times_seen\": 72.0}, {\"site\": 674, \"mutant\": \"T\", \"escape\": 0.22454825525476618, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.0604, \"times_seen\": 50.0}, {\"site\": 674, \"mutant\": \"V\", \"escape\": 0.20669295423467077, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.2324, \"times_seen\": 52.0}, {\"site\": 674, \"mutant\": \"W\", \"escape\": -0.028820420369716566, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.1285, \"times_seen\": 28.0}, {\"site\": 674, \"mutant\": \"Y\", \"escape\": -0.02630493691683049, \"epitope\": \"epitope 1\", \"reference_site\": \"677\", \"functional effect\": 0.2683, \"times_seen\": 19.0}, {\"site\": 675, \"mutant\": \"*\", \"escape\": -0.006297153368402775, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -2.6582, \"times_seen\": 2.0}, {\"site\": 675, \"mutant\": \"-\", \"escape\": 0.01588264538752439, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 675, \"mutant\": \"A\", \"escape\": -0.011980742273547692, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.1094, \"times_seen\": 54.0}, {\"site\": 675, \"mutant\": \"C\", \"escape\": 2.074501789060628e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.4261, \"times_seen\": 11.0}, {\"site\": 675, \"mutant\": \"D\", \"escape\": 0.008985512506510734, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.028, \"times_seen\": 23.0}, {\"site\": 675, \"mutant\": \"E\", \"escape\": -0.038926820212537135, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0433, \"times_seen\": 13.0}, {\"site\": 675, \"mutant\": \"F\", \"escape\": -0.7062011341831538, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0114, \"times_seen\": 24.0}, {\"site\": 675, \"mutant\": \"G\", \"escape\": 0.026438266583220817, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.1251, \"times_seen\": 33.0}, {\"site\": 675, \"mutant\": \"H\", \"escape\": 0.0009846075307807904, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0667, \"times_seen\": 17.0}, {\"site\": 675, \"mutant\": \"I\", \"escape\": 0.00016107333383528723, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.065, \"times_seen\": 54.0}, {\"site\": 675, \"mutant\": \"K\", \"escape\": -0.014644870122958027, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0199, \"times_seen\": 19.0}, {\"site\": 675, \"mutant\": \"L\", \"escape\": -0.03851778754630314, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.1588, \"times_seen\": 37.0}, {\"site\": 675, \"mutant\": \"M\", \"escape\": -0.008294931264699186, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.1123, \"times_seen\": 15.0}, {\"site\": 675, \"mutant\": \"N\", \"escape\": 0.012278131695982636, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0573, \"times_seen\": 30.0}, {\"site\": 675, \"mutant\": \"P\", \"escape\": 0.41836883192289526, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.082, \"times_seen\": 49.0}, {\"site\": 675, \"mutant\": \"Q\", \"escape\": 0.07129897571182332, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.084, \"times_seen\": 12.0}, {\"site\": 675, \"mutant\": \"R\", \"escape\": -0.01570484934530447, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0321, \"times_seen\": 28.0}, {\"site\": 675, \"mutant\": \"S\", \"escape\": -0.03966354420043238, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0164, \"times_seen\": 81.0}, {\"site\": 675, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 675, \"mutant\": \"V\", \"escape\": -0.028803623535556953, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": -0.0736, \"times_seen\": 34.0}, {\"site\": 675, \"mutant\": \"W\", \"escape\": -0.0015272947915045112, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.0339, \"times_seen\": 1.0}, {\"site\": 675, \"mutant\": \"Y\", \"escape\": -0.013987318152210958, \"epitope\": \"epitope 1\", \"reference_site\": \"678\", \"functional effect\": 0.1426, \"times_seen\": 15.0}, {\"site\": 676, \"mutant\": \"*\", \"escape\": -0.013456181929185906, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -2.5024, \"times_seen\": 7.0}, {\"site\": 676, \"mutant\": \"-\", \"escape\": 0.016228723887805826, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 676, \"mutant\": \"A\", \"escape\": -0.03206603319358363, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0013, \"times_seen\": 41.0}, {\"site\": 676, \"mutant\": \"C\", \"escape\": 0.0013842169756455426, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.348, \"times_seen\": 11.0}, {\"site\": 676, \"mutant\": \"D\", \"escape\": 0.015346542375059303, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0777, \"times_seen\": 25.0}, {\"site\": 676, \"mutant\": \"E\", \"escape\": 0.1379419872080331, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1234, \"times_seen\": 61.0}, {\"site\": 676, \"mutant\": \"F\", \"escape\": -0.011455109056727917, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.031, \"times_seen\": 11.0}, {\"site\": 676, \"mutant\": \"G\", \"escape\": 0.005003169316342581, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1033, \"times_seen\": 53.0}, {\"site\": 676, \"mutant\": \"H\", \"escape\": -0.3760970088575768, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1203, \"times_seen\": 19.0}, {\"site\": 676, \"mutant\": \"I\", \"escape\": 0.11322671817431343, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 676, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 676, \"mutant\": \"L\", \"escape\": -0.02987807985437675, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0434, \"times_seen\": 64.0}, {\"site\": 676, \"mutant\": \"M\", \"escape\": -0.005385657361578447, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1142, \"times_seen\": 48.0}, {\"site\": 676, \"mutant\": \"N\", \"escape\": -0.171674131431124, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0945, \"times_seen\": 45.0}, {\"site\": 676, \"mutant\": \"P\", \"escape\": -0.17522966437177884, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.1529, \"times_seen\": 54.0}, {\"site\": 676, \"mutant\": \"Q\", \"escape\": 0.19880168528300993, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.2082, \"times_seen\": 41.0}, {\"site\": 676, \"mutant\": \"R\", \"escape\": 0.26983405008256994, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.0367, \"times_seen\": 104.0}, {\"site\": 676, \"mutant\": \"S\", \"escape\": 0.016444662945992467, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0645, \"times_seen\": 92.0}, {\"site\": 676, \"mutant\": \"T\", \"escape\": -0.2980479928869751, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0274, \"times_seen\": 77.0}, {\"site\": 676, \"mutant\": \"V\", \"escape\": -0.027081466648680108, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": 0.0752, \"times_seen\": 50.0}, {\"site\": 676, \"mutant\": \"W\", \"escape\": 0.008410986794097571, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.1011, \"times_seen\": 23.0}, {\"site\": 676, \"mutant\": \"Y\", \"escape\": 0.7179295126721648, \"epitope\": \"epitope 1\", \"reference_site\": \"679\", \"functional effect\": -0.0373, \"times_seen\": 36.0}, {\"site\": 677, \"mutant\": \"A\", \"escape\": -0.027135943712122874, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.05, \"times_seen\": 13.0}, {\"site\": 677, \"mutant\": \"C\", \"escape\": -0.00296615896361509, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.1612, \"times_seen\": 2.0}, {\"site\": 677, \"mutant\": \"F\", \"escape\": 0.010422036324717134, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.1095, \"times_seen\": 36.0}, {\"site\": 677, \"mutant\": \"G\", \"escape\": -0.020368561231384467, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.1538, \"times_seen\": 3.0}, {\"site\": 677, \"mutant\": \"H\", \"escape\": 1.3053736584230542, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.2677, \"times_seen\": 13.0}, {\"site\": 677, \"mutant\": \"I\", \"escape\": -0.0028997239788961216, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.0077, \"times_seen\": 1.0}, {\"site\": 677, \"mutant\": \"N\", \"escape\": -0.02705492236299619, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0832, \"times_seen\": 12.0}, {\"site\": 677, \"mutant\": \"P\", \"escape\": 0.05475781567643415, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0819, \"times_seen\": 17.0}, {\"site\": 677, \"mutant\": \"R\", \"escape\": -0.24272257549831386, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0276, \"times_seen\": 16.0}, {\"site\": 677, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 677, \"mutant\": \"T\", \"escape\": 0.03690883185537, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": 0.0732, \"times_seen\": 10.0}, {\"site\": 677, \"mutant\": \"W\", \"escape\": 0.046123973673821324, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.19, \"times_seen\": 8.0}, {\"site\": 677, \"mutant\": \"Y\", \"escape\": -0.00775156575773117, \"epitope\": \"epitope 1\", \"reference_site\": \"680\", \"functional effect\": -0.0183, \"times_seen\": 4.0}, {\"site\": 678, \"mutant\": \"*\", \"escape\": 0.000855359968088825, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -2.9417, \"times_seen\": 2.0}, {\"site\": 678, \"mutant\": \"A\", \"escape\": -0.8058699793249385, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0278, \"times_seen\": 33.0}, {\"site\": 678, \"mutant\": \"C\", \"escape\": 0.13215597411084318, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.056, \"times_seen\": 45.0}, {\"site\": 678, \"mutant\": \"D\", \"escape\": 1.0504978357764392, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.2697, \"times_seen\": 49.0}, {\"site\": 678, \"mutant\": \"E\", \"escape\": -0.036941137566930626, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.0991, \"times_seen\": 16.0}, {\"site\": 678, \"mutant\": \"F\", \"escape\": 1.1069991242500465, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0028, \"times_seen\": 26.0}, {\"site\": 678, \"mutant\": \"G\", \"escape\": -0.026985633245903626, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.1376, \"times_seen\": 34.0}, {\"site\": 678, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 678, \"mutant\": \"I\", \"escape\": -0.21347566980405727, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.0187, \"times_seen\": 20.0}, {\"site\": 678, \"mutant\": \"K\", \"escape\": 0.0422714874203584, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.062, \"times_seen\": 21.0}, {\"site\": 678, \"mutant\": \"L\", \"escape\": 0.0487615139483624, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0037, \"times_seen\": 114.0}, {\"site\": 678, \"mutant\": \"M\", \"escape\": -0.032843557003540434, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.008, \"times_seen\": 17.0}, {\"site\": 678, \"mutant\": \"N\", \"escape\": 0.3535042114078185, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0425, \"times_seen\": 42.0}, {\"site\": 678, \"mutant\": \"P\", \"escape\": -0.004383965264672594, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": 0.1077, \"times_seen\": 60.0}, {\"site\": 678, \"mutant\": \"Q\", \"escape\": -0.026451752240864542, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0064, \"times_seen\": 41.0}, {\"site\": 678, \"mutant\": \"R\", \"escape\": 0.19925194091631807, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.1568, \"times_seen\": 91.0}, {\"site\": 678, \"mutant\": \"S\", \"escape\": 0.033768128491908446, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0007, \"times_seen\": 119.0}, {\"site\": 678, \"mutant\": \"T\", \"escape\": 0.01835525723375405, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0108, \"times_seen\": 58.0}, {\"site\": 678, \"mutant\": \"V\", \"escape\": -0.13196567903750617, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0938, \"times_seen\": 29.0}, {\"site\": 678, \"mutant\": \"W\", \"escape\": 0.050271105710722935, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.1172, \"times_seen\": 13.0}, {\"site\": 678, \"mutant\": \"Y\", \"escape\": 0.003602120484931357, \"epitope\": \"epitope 1\", \"reference_site\": \"681\", \"functional effect\": -0.0357, \"times_seen\": 85.0}, {\"site\": 679, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.7621, \"times_seen\": null}, {\"site\": 679, \"mutant\": \"G\", \"escape\": 0.6315122824342211, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.3557, \"times_seen\": 72.0}, {\"site\": 679, \"mutant\": \"I\", \"escape\": 0.007350079981407189, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"mutant\": \"K\", \"escape\": 0.050946752001912975, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.2684, \"times_seen\": 15.0}, {\"site\": 679, \"mutant\": \"L\", \"escape\": 1.5342898343870661, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.3728, \"times_seen\": 25.0}, {\"site\": 679, \"mutant\": \"M\", \"escape\": 0.035526595906598464, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.397, \"times_seen\": 7.0}, {\"site\": 679, \"mutant\": \"Q\", \"escape\": -0.04559428060013707, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.2007, \"times_seen\": 13.0}, {\"site\": 679, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 679, \"mutant\": \"S\", \"escape\": 0.5489275411104948, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.0544, \"times_seen\": 6.0}, {\"site\": 679, \"mutant\": \"T\", \"escape\": 0.005550555706996915, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"mutant\": \"W\", \"escape\": 0.8031538180598708, \"epitope\": \"epitope 1\", \"reference_site\": \"682\", \"functional effect\": 0.3201, \"times_seen\": 97.0}, {\"site\": 680, \"mutant\": \"G\", \"escape\": 0.08867787840495887, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.1477, \"times_seen\": 20.0}, {\"site\": 680, \"mutant\": \"K\", \"escape\": -0.013947777343663861, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0466, \"times_seen\": 13.0}, {\"site\": 680, \"mutant\": \"L\", \"escape\": -0.00946251154132443, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0351, \"times_seen\": 5.0}, {\"site\": 680, \"mutant\": \"M\", \"escape\": 0.017558901456718845, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0149, \"times_seen\": 5.0}, {\"site\": 680, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.0362, \"times_seen\": null}, {\"site\": 680, \"mutant\": \"Q\", \"escape\": 0.04004003738704631, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0824, \"times_seen\": 17.0}, {\"site\": 680, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 680, \"mutant\": \"S\", \"escape\": -0.004019310042742642, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.2031, \"times_seen\": 6.0}, {\"site\": 680, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": 0.019, \"times_seen\": null}, {\"site\": 680, \"mutant\": \"W\", \"escape\": 0.45849524899112687, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0267, \"times_seen\": 50.0}, {\"site\": 680, \"mutant\": \"Y\", \"escape\": 0.003779919987645812, \"epitope\": \"epitope 1\", \"reference_site\": \"683\", \"functional effect\": -0.0464, \"times_seen\": 1.0}, {\"site\": 681, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 681, \"mutant\": \"E\", \"escape\": -0.01792717616706816, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.2704, \"times_seen\": 8.0}, {\"site\": 681, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": -0.2085, \"times_seen\": null}, {\"site\": 681, \"mutant\": \"P\", \"escape\": -0.004615581399971026, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0403, \"times_seen\": 2.0}, {\"site\": 681, \"mutant\": \"S\", \"escape\": -0.005168821228012008, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": -0.022, \"times_seen\": 17.0}, {\"site\": 681, \"mutant\": \"T\", \"escape\": 0.012781114294383729, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0168, \"times_seen\": 60.0}, {\"site\": 681, \"mutant\": \"V\", \"escape\": 0.02838987597635027, \"epitope\": \"epitope 1\", \"reference_site\": \"684\", \"functional effect\": 0.0507, \"times_seen\": 14.0}, {\"site\": 682, \"mutant\": \"G\", \"escape\": 0.032063417742847655, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.4033, \"times_seen\": 35.0}, {\"site\": 682, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": -0.0979, \"times_seen\": null}, {\"site\": 682, \"mutant\": \"K\", \"escape\": 1.0198551451778122, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.4203, \"times_seen\": 24.0}, {\"site\": 682, \"mutant\": \"M\", \"escape\": -0.04453392925463159, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.1163, \"times_seen\": 6.0}, {\"site\": 682, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 682, \"mutant\": \"S\", \"escape\": 0.02141963127153579, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": 0.3921, \"times_seen\": 7.0}, {\"site\": 682, \"mutant\": \"W\", \"escape\": 0.020924489050703578, \"epitope\": \"epitope 1\", \"reference_site\": \"685\", \"functional effect\": -0.1572, \"times_seen\": 3.0}, {\"site\": 683, \"mutant\": \"A\", \"escape\": 0.01671742155856922, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.1162, \"times_seen\": 1.0}, {\"site\": 683, \"mutant\": \"C\", \"escape\": 0.023010804953032937, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": -0.2995, \"times_seen\": 2.0}, {\"site\": 683, \"mutant\": \"F\", \"escape\": 0.001372317945090643, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.0832, \"times_seen\": 2.0}, {\"site\": 683, \"mutant\": \"G\", \"escape\": 0.014368578260338551, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.355, \"times_seen\": 11.0}, {\"site\": 683, \"mutant\": \"I\", \"escape\": 0.018628122390206205, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.4224, \"times_seen\": 13.0}, {\"site\": 683, \"mutant\": \"N\", \"escape\": 0.002271203972762989, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.1903, \"times_seen\": 5.0}, {\"site\": 683, \"mutant\": \"P\", \"escape\": 0.0026492598080621, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.0474, \"times_seen\": 3.0}, {\"site\": 683, \"mutant\": \"R\", \"escape\": -0.01145507051485707, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": -0.0649, \"times_seen\": 6.0}, {\"site\": 683, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 683, \"mutant\": \"T\", \"escape\": 0.026488448012070804, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.397, \"times_seen\": 2.0}, {\"site\": 683, \"mutant\": \"Y\", \"escape\": -0.0035481623272066, \"epitope\": \"epitope 1\", \"reference_site\": \"686\", \"functional effect\": 0.1546, \"times_seen\": 6.0}, {\"site\": 684, \"mutant\": \"A\", \"escape\": 0.0008491450038228256, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.0484, \"times_seen\": 10.0}, {\"site\": 684, \"mutant\": \"E\", \"escape\": 0.0050525348177917085, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 684, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.9512, \"times_seen\": null}, {\"site\": 684, \"mutant\": \"I\", \"escape\": 0.07915724497761203, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.1331, \"times_seen\": 24.0}, {\"site\": 684, \"mutant\": \"L\", \"escape\": -0.007968295018868612, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": -0.1648, \"times_seen\": 11.0}, {\"site\": 684, \"mutant\": \"M\", \"escape\": -0.017910570794389066, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.0449, \"times_seen\": 19.0}, {\"site\": 684, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"687\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 685, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -2.9234, \"times_seen\": null}, {\"site\": 685, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 685, \"mutant\": \"C\", \"escape\": -0.11917010455402612, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.2151, \"times_seen\": 18.0}, {\"site\": 685, \"mutant\": \"D\", \"escape\": -0.04335020065482319, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.1009, \"times_seen\": 28.0}, {\"site\": 685, \"mutant\": \"E\", \"escape\": 1.368415241473632, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.2832, \"times_seen\": 13.0}, {\"site\": 685, \"mutant\": \"F\", \"escape\": -0.012081184915058229, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.4225, \"times_seen\": 6.0}, {\"site\": 685, \"mutant\": \"G\", \"escape\": -0.027499033838356304, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0176, \"times_seen\": 37.0}, {\"site\": 685, \"mutant\": \"H\", \"escape\": 0.01937037669673782, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.1275, \"times_seen\": 8.0}, {\"site\": 685, \"mutant\": \"I\", \"escape\": -0.004555611614849553, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.5499, \"times_seen\": 1.0}, {\"site\": 685, \"mutant\": \"K\", \"escape\": -0.007229425454628476, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.154, \"times_seen\": 1.0}, {\"site\": 685, \"mutant\": \"L\", \"escape\": -1.6305896780297011, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.064, \"times_seen\": 14.0}, {\"site\": 685, \"mutant\": \"M\", \"escape\": -0.01649148973033323, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.099, \"times_seen\": 7.0}, {\"site\": 685, \"mutant\": \"N\", \"escape\": 0.004755599408529706, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0169, \"times_seen\": 4.0}, {\"site\": 685, \"mutant\": \"P\", \"escape\": 0.051679133531036286, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0709, \"times_seen\": 20.0}, {\"site\": 685, \"mutant\": \"Q\", \"escape\": -0.0132018557891567, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.2707, \"times_seen\": 7.0}, {\"site\": 685, \"mutant\": \"R\", \"escape\": 0.00653163632344587, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0171, \"times_seen\": 26.0}, {\"site\": 685, \"mutant\": \"S\", \"escape\": 0.017503627834588795, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.0361, \"times_seen\": 74.0}, {\"site\": 685, \"mutant\": \"T\", \"escape\": -1.4230723050091374, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.0197, \"times_seen\": 65.0}, {\"site\": 685, \"mutant\": \"V\", \"escape\": -0.0006679200101818478, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": 0.0917, \"times_seen\": 90.0}, {\"site\": 685, \"mutant\": \"W\", \"escape\": 0.023551630174370723, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.1542, \"times_seen\": 7.0}, {\"site\": 685, \"mutant\": \"Y\", \"escape\": -0.014539149256285756, \"epitope\": \"epitope 1\", \"reference_site\": \"688\", \"functional effect\": -0.2307, \"times_seen\": 9.0}, {\"site\": 686, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 686, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -0.173, \"times_seen\": null}, {\"site\": 686, \"mutant\": \"D\", \"escape\": 0.006636735052872384, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -0.3588, \"times_seen\": 3.0}, {\"site\": 686, \"mutant\": \"G\", \"escape\": -0.020851981375438026, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0158, \"times_seen\": 9.0}, {\"site\": 686, \"mutant\": \"I\", \"escape\": 0.01387716730844086, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": -0.1987, \"times_seen\": 20.0}, {\"site\": 686, \"mutant\": \"N\", \"escape\": -0.03284690875776956, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0178, \"times_seen\": 46.0}, {\"site\": 686, \"mutant\": \"R\", \"escape\": 0.5093248484642559, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0532, \"times_seen\": 40.0}, {\"site\": 686, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 686, \"mutant\": \"T\", \"escape\": -0.004573950123700958, \"epitope\": \"epitope 1\", \"reference_site\": \"689\", \"functional effect\": 0.2043, \"times_seen\": 4.0}, {\"site\": 687, \"mutant\": \"*\", \"escape\": -0.002189925153381582, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -2.8604, \"times_seen\": 1.0}, {\"site\": 687, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 687, \"mutant\": \"H\", \"escape\": 0.000885707333445839, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 687, \"mutant\": \"K\", \"escape\": -0.010909435300333057, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.2871, \"times_seen\": 23.0}, {\"site\": 687, \"mutant\": \"L\", \"escape\": -0.0050696606456028135, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -0.3511, \"times_seen\": 34.0}, {\"site\": 687, \"mutant\": \"P\", \"escape\": -0.008103732636641667, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": -0.041, \"times_seen\": 5.0}, {\"site\": 687, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 687, \"mutant\": \"R\", \"escape\": 0.027303287604338138, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.0963, \"times_seen\": 29.0}, {\"site\": 687, \"mutant\": \"S\", \"escape\": 0.017127305039690257, \"epitope\": \"epitope 1\", \"reference_site\": \"690\", \"functional effect\": 0.155, \"times_seen\": 4.0}, {\"site\": 688, \"mutant\": \"A\", \"escape\": -0.024059405380894253, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.1149, \"times_seen\": 9.0}, {\"site\": 688, \"mutant\": \"C\", \"escape\": -0.0013423205138218914, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.0782, \"times_seen\": 1.0}, {\"site\": 688, \"mutant\": \"D\", \"escape\": 0.20987211982107426, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.8101, \"times_seen\": 8.0}, {\"site\": 688, \"mutant\": \"F\", \"escape\": -0.08601520786002709, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.682, \"times_seen\": 35.0}, {\"site\": 688, \"mutant\": \"G\", \"escape\": -0.018240322729943317, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.1487, \"times_seen\": 6.0}, {\"site\": 688, \"mutant\": \"I\", \"escape\": -0.006410608311674108, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.0558, \"times_seen\": 4.0}, {\"site\": 688, \"mutant\": \"N\", \"escape\": -0.05507982956926666, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.0284, \"times_seen\": 26.0}, {\"site\": 688, \"mutant\": \"P\", \"escape\": 0.02964855698385869, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.8109, \"times_seen\": 15.0}, {\"site\": 688, \"mutant\": \"R\", \"escape\": -0.001998524621706054, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 688, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 688, \"mutant\": \"T\", \"escape\": 0.008909985078398606, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.0433, \"times_seen\": 8.0}, {\"site\": 688, \"mutant\": \"Y\", \"escape\": -0.049470370706108706, \"epitope\": \"epitope 1\", \"reference_site\": \"691\", \"functional effect\": -0.498, \"times_seen\": 25.0}, {\"site\": 689, \"mutant\": \"F\", \"escape\": -0.006275721289472261, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -0.0477, \"times_seen\": 4.0}, {\"site\": 689, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 689, \"mutant\": \"L\", \"escape\": 0.031058834254514663, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -0.3436, \"times_seen\": 3.0}, {\"site\": 689, \"mutant\": \"M\", \"escape\": -0.015357561006385793, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -0.636, \"times_seen\": 6.0}, {\"site\": 689, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -3.2584, \"times_seen\": null}, {\"site\": 689, \"mutant\": \"S\", \"escape\": 0.008939901155378703, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -2.4933, \"times_seen\": 3.0}, {\"site\": 689, \"mutant\": \"T\", \"escape\": 0.0003537718203572402, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -2.0274, \"times_seen\": 1.0}, {\"site\": 689, \"mutant\": \"V\", \"escape\": 0.011406207729296094, \"epitope\": \"epitope 1\", \"reference_site\": \"692\", \"functional effect\": -1.4086, \"times_seen\": 2.0}, {\"site\": 690, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"F\", \"escape\": 0.00110920357095178, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -0.3145, \"times_seen\": 6.0}, {\"site\": 690, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.3379, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.3074, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"S\", \"escape\": 0.023588033049207438, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -1.368, \"times_seen\": 1.0}, {\"site\": 690, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -3.066, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"V\", \"escape\": 0.028124599340071013, \"epitope\": \"epitope 1\", \"reference_site\": \"693\", \"functional effect\": -0.1459, \"times_seen\": 19.0}, {\"site\": 691, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -3.0186, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -3.2784, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"S\", \"escape\": -0.019848671007466453, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -2.0572, \"times_seen\": 14.0}, {\"site\": 691, \"mutant\": \"T\", \"escape\": -0.020653973607134585, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": -1.6896, \"times_seen\": 13.0}, {\"site\": 691, \"mutant\": \"V\", \"escape\": -0.007090167665083806, \"epitope\": \"epitope 1\", \"reference_site\": \"694\", \"functional effect\": 0.1418, \"times_seen\": 21.0}, {\"site\": 693, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 693, \"mutant\": \"A\", \"escape\": -0.00016800250077692735, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.8277, \"times_seen\": 5.0}, {\"site\": 693, \"mutant\": \"I\", \"escape\": -0.012314888764651035, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.1373, \"times_seen\": 14.0}, {\"site\": 693, \"mutant\": \"K\", \"escape\": -0.019064659288691038, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.2243, \"times_seen\": 7.0}, {\"site\": 693, \"mutant\": \"N\", \"escape\": 0.003384800724626227, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -1.8929, \"times_seen\": 3.0}, {\"site\": 693, \"mutant\": \"R\", \"escape\": 0.017165723415492475, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.2672, \"times_seen\": 1.0}, {\"site\": 693, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": -0.3019, \"times_seen\": null}, {\"site\": 693, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"696\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"I\", \"escape\": -0.24495884798360754, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -0.307, \"times_seen\": 45.0}, {\"site\": 694, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"L\", \"escape\": -0.009222500536078797, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -0.48, \"times_seen\": 7.0}, {\"site\": 694, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -2.6723, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"T\", \"escape\": -0.02134505839772055, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -2.7727, \"times_seen\": 4.0}, {\"site\": 694, \"mutant\": \"V\", \"escape\": 0.007343637199815571, \"epitope\": \"epitope 1\", \"reference_site\": \"697\", \"functional effect\": -1.9839, \"times_seen\": 2.0}, {\"site\": 695, \"mutant\": \"A\", \"escape\": -0.0013831390791504263, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.6287, \"times_seen\": 1.0}, {\"site\": 695, \"mutant\": \"C\", \"escape\": -0.003850587657438108, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.3265, \"times_seen\": 1.0}, {\"site\": 695, \"mutant\": \"G\", \"escape\": -0.038150028109472295, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.3187, \"times_seen\": 4.0}, {\"site\": 695, \"mutant\": \"I\", \"escape\": -0.007706211895126659, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -1.1388, \"times_seen\": 3.0}, {\"site\": 695, \"mutant\": \"L\", \"escape\": -0.007250240750394298, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -0.1677, \"times_seen\": 2.0}, {\"site\": 695, \"mutant\": \"N\", \"escape\": -0.0061321687324893065, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 695, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": -1.3615, \"times_seen\": null}, {\"site\": 695, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"698\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -3.0141, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"I\", \"escape\": -0.032521303953270755, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -0.3115, \"times_seen\": 10.0}, {\"site\": 696, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"M\", \"escape\": -0.009546405072078528, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -0.5968, \"times_seen\": 3.0}, {\"site\": 696, \"mutant\": \"P\", \"escape\": -0.013181424153857632, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -1.1541, \"times_seen\": 7.0}, {\"site\": 696, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -0.7797, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"R\", \"escape\": 0.020486509520623652, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -2.2536, \"times_seen\": 1.0}, {\"site\": 696, \"mutant\": \"V\", \"escape\": -0.004150990266187838, \"epitope\": \"epitope 1\", \"reference_site\": \"699\", \"functional effect\": -1.0615, \"times_seen\": 2.0}, {\"site\": 697, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.3439, \"times_seen\": null}, {\"site\": 697, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -3.0251, \"times_seen\": null}, {\"site\": 697, \"mutant\": \"E\", \"escape\": 0.002236783308889256, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.1499, \"times_seen\": 1.0}, {\"site\": 697, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 697, \"mutant\": \"R\", \"escape\": -0.01050330202258045, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.9319, \"times_seen\": 11.0}, {\"site\": 697, \"mutant\": \"V\", \"escape\": -0.004730946459038101, \"epitope\": \"epitope 1\", \"reference_site\": \"700\", \"functional effect\": -2.4878, \"times_seen\": 2.0}, {\"site\": 698, \"mutant\": \"*\", \"escape\": -0.011237182246781973, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -2.4326, \"times_seen\": 4.0}, {\"site\": 698, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 698, \"mutant\": \"C\", \"escape\": -0.033111973920179845, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.3332, \"times_seen\": 18.0}, {\"site\": 698, \"mutant\": \"D\", \"escape\": -0.029572847436164118, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.1895, \"times_seen\": 13.0}, {\"site\": 698, \"mutant\": \"E\", \"escape\": 0.0004417643860018327, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.3037, \"times_seen\": 36.0}, {\"site\": 698, \"mutant\": \"F\", \"escape\": -0.02008695233186445, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.6567, \"times_seen\": 6.0}, {\"site\": 698, \"mutant\": \"G\", \"escape\": 0.15958107823954434, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.5186, \"times_seen\": 45.0}, {\"site\": 698, \"mutant\": \"H\", \"escape\": 0.02070920032494295, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.3038, \"times_seen\": 15.0}, {\"site\": 698, \"mutant\": \"I\", \"escape\": -0.02011504620784983, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.6607, \"times_seen\": 4.0}, {\"site\": 698, \"mutant\": \"K\", \"escape\": 0.0006271705111781718, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.269, \"times_seen\": 16.0}, {\"site\": 698, \"mutant\": \"L\", \"escape\": 0.02944231794877072, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -2.1994, \"times_seen\": 10.0}, {\"site\": 698, \"mutant\": \"M\", \"escape\": -1.3300699223861412, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.2184, \"times_seen\": 11.0}, {\"site\": 698, \"mutant\": \"N\", \"escape\": -0.007539151439689642, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.1154, \"times_seen\": 16.0}, {\"site\": 698, \"mutant\": \"P\", \"escape\": 0.09244761734570779, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.2828, \"times_seen\": 43.0}, {\"site\": 698, \"mutant\": \"Q\", \"escape\": -0.0038669554405607377, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.1819, \"times_seen\": 16.0}, {\"site\": 698, \"mutant\": \"R\", \"escape\": 0.21320653800970635, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.0393, \"times_seen\": 51.0}, {\"site\": 698, \"mutant\": \"S\", \"escape\": 0.6549050853221023, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": 0.1561, \"times_seen\": 71.0}, {\"site\": 698, \"mutant\": \"T\", \"escape\": 0.04860415358379725, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.0478, \"times_seen\": 78.0}, {\"site\": 698, \"mutant\": \"V\", \"escape\": -1.2813069985588927, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -0.3771, \"times_seen\": 68.0}, {\"site\": 698, \"mutant\": \"W\", \"escape\": 0.0020964154039228968, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.306, \"times_seen\": 9.0}, {\"site\": 698, \"mutant\": \"Y\", \"escape\": -0.03199632119683635, \"epitope\": \"epitope 1\", \"reference_site\": \"701\", \"functional effect\": -1.6371, \"times_seen\": 6.0}, {\"site\": 699, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 699, \"mutant\": \"A\", \"escape\": 0.0020769468642139544, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -0.9622, \"times_seen\": 6.0}, {\"site\": 699, \"mutant\": \"D\", \"escape\": -0.025216323216203304, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -0.0147, \"times_seen\": 23.0}, {\"site\": 699, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 699, \"mutant\": \"G\", \"escape\": -0.01803342052470066, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -1.3361, \"times_seen\": 5.0}, {\"site\": 699, \"mutant\": \"K\", \"escape\": 0.7077197415598622, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -1.9836, \"times_seen\": 23.0}, {\"site\": 699, \"mutant\": \"Q\", \"escape\": -0.1488588036749685, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -1.0118, \"times_seen\": 29.0}, {\"site\": 699, \"mutant\": \"V\", \"escape\": 0.013066438713808502, \"epitope\": \"epitope 1\", \"reference_site\": \"702\", \"functional effect\": -0.4209, \"times_seen\": 9.0}, {\"site\": 700, \"mutant\": \"D\", \"escape\": 0.01775104133027669, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": -1.3029, \"times_seen\": 2.0}, {\"site\": 700, \"mutant\": \"F\", \"escape\": 0.0455857677188343, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2062, \"times_seen\": 5.0}, {\"site\": 700, \"mutant\": \"H\", \"escape\": -0.0027450248663112298, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.1572, \"times_seen\": 3.0}, {\"site\": 700, \"mutant\": \"I\", \"escape\": -0.0004563189506977918, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2645, \"times_seen\": 8.0}, {\"site\": 700, \"mutant\": \"K\", \"escape\": 0.022593053478675306, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2939, \"times_seen\": 13.0}, {\"site\": 700, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 700, \"mutant\": \"S\", \"escape\": 0.01842449542441781, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.2507, \"times_seen\": 31.0}, {\"site\": 700, \"mutant\": \"T\", \"escape\": 0.054346649393216914, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.3242, \"times_seen\": 21.0}, {\"site\": 700, \"mutant\": \"Y\", \"escape\": -0.01113247033937543, \"epitope\": \"epitope 1\", \"reference_site\": \"703\", \"functional effect\": 0.3651, \"times_seen\": 11.0}, {\"site\": 701, \"mutant\": \"A\", \"escape\": 0.0003225028784329189, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": -0.0676, \"times_seen\": 3.0}, {\"site\": 701, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": -0.8183, \"times_seen\": null}, {\"site\": 701, \"mutant\": \"F\", \"escape\": -0.0014614416208187425, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 701, \"mutant\": \"L\", \"escape\": 0.49362602505718467, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.3483, \"times_seen\": 21.0}, {\"site\": 701, \"mutant\": \"P\", \"escape\": -0.03538201853446228, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": -1.5507, \"times_seen\": 15.0}, {\"site\": 701, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 701, \"mutant\": \"T\", \"escape\": 0.00483544234348818, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.3651, \"times_seen\": 7.0}, {\"site\": 701, \"mutant\": \"Y\", \"escape\": -0.41197504860056616, \"epitope\": \"epitope 1\", \"reference_site\": \"704\", \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 702, \"mutant\": \"A\", \"escape\": -0.013388682932462728, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -2.517, \"times_seen\": 2.0}, {\"site\": 702, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -2.9829, \"times_seen\": null}, {\"site\": 702, \"mutant\": \"F\", \"escape\": -0.014124643717130302, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -2.0341, \"times_seen\": 5.0}, {\"site\": 702, \"mutant\": \"I\", \"escape\": 0.016550763847704254, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": 0.2691, \"times_seen\": 20.0}, {\"site\": 702, \"mutant\": \"L\", \"escape\": -0.37332221397246806, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -0.0799, \"times_seen\": 40.0}, {\"site\": 702, \"mutant\": \"M\", \"escape\": -0.0009468945974105729, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": -1.7662, \"times_seen\": 4.0}, {\"site\": 702, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"705\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -2.0658, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -2.8496, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"G\", \"escape\": -0.01593456808618294, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.7527, \"times_seen\": 4.0}, {\"site\": 703, \"mutant\": \"L\", \"escape\": -0.014811453003729186, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.2316, \"times_seen\": 2.0}, {\"site\": 703, \"mutant\": \"P\", \"escape\": -0.08378728406247554, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 703, \"mutant\": \"S\", \"escape\": 0.007606782649582638, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.5893, \"times_seen\": 12.0}, {\"site\": 703, \"mutant\": \"T\", \"escape\": -0.01640813546134342, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -1.6831, \"times_seen\": 4.0}, {\"site\": 703, \"mutant\": \"V\", \"escape\": -1.186311522034248, \"epitope\": \"epitope 1\", \"reference_site\": \"706\", \"functional effect\": -2.1539, \"times_seen\": 3.0}, {\"site\": 704, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.2896, \"times_seen\": null}, {\"site\": 704, \"mutant\": \"C\", \"escape\": -0.004330306513729734, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.6432, \"times_seen\": 1.0}, {\"site\": 704, \"mutant\": \"H\", \"escape\": -0.00018890630006834598, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.3384, \"times_seen\": 1.0}, {\"site\": 704, \"mutant\": \"L\", \"escape\": -0.003354115570397671, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": -2.1444, \"times_seen\": 1.0}, {\"site\": 704, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"707\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"A\", \"escape\": -0.0052779390614512214, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -0.8247, \"times_seen\": 4.0}, {\"site\": 705, \"mutant\": \"C\", \"escape\": -0.008950780108014665, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.8552, \"times_seen\": 3.0}, {\"site\": 705, \"mutant\": \"F\", \"escape\": 0.01295692706288142, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.5027, \"times_seen\": 5.0}, {\"site\": 705, \"mutant\": \"G\", \"escape\": 0.02369048075465027, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -0.5849, \"times_seen\": 17.0}, {\"site\": 705, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.4402, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.8747, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"N\", \"escape\": -0.002633154020724169, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -1.0821, \"times_seen\": 16.0}, {\"site\": 705, \"mutant\": \"R\", \"escape\": -0.006612552402374818, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": -2.0092, \"times_seen\": 2.0}, {\"site\": 705, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"T\", \"escape\": -0.0038050916646212925, \"epitope\": \"epitope 1\", \"reference_site\": \"708\", \"functional effect\": 0.2883, \"times_seen\": 3.0}, {\"site\": 706, \"mutant\": \"-\", \"escape\": -0.0019359253396846368, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.1873, \"times_seen\": 1.0}, {\"site\": 706, \"mutant\": \"D\", \"escape\": -0.0052344296703694315, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": 0.2955, \"times_seen\": 2.0}, {\"site\": 706, \"mutant\": \"I\", \"escape\": 0.01012967904453311, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.7003, \"times_seen\": 4.0}, {\"site\": 706, \"mutant\": \"K\", \"escape\": -0.01427870871231671, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.7224, \"times_seen\": 6.0}, {\"site\": 706, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 706, \"mutant\": \"S\", \"escape\": -0.0682543160635678, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -2.0355, \"times_seen\": 13.0}, {\"site\": 706, \"mutant\": \"T\", \"escape\": 0.008596181223831927, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -2.0548, \"times_seen\": 7.0}, {\"site\": 706, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -2.9375, \"times_seen\": null}, {\"site\": 706, \"mutant\": \"Y\", \"escape\": -0.011202015877810171, \"epitope\": \"epitope 1\", \"reference_site\": \"709\", \"functional effect\": -1.5874, \"times_seen\": 14.0}, {\"site\": 707, \"mutant\": \"D\", \"escape\": -0.02401014812158664, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 0.1446, \"times_seen\": 40.0}, {\"site\": 707, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 707, \"mutant\": \"K\", \"escape\": 0.026229788542109583, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -0.4409, \"times_seen\": 16.0}, {\"site\": 707, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 707, \"mutant\": \"Q\", \"escape\": -0.008297649916710864, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -1.1788, \"times_seen\": 1.0}, {\"site\": 707, \"mutant\": \"S\", \"escape\": 0.07815472575604206, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -0.7601, \"times_seen\": 12.0}, {\"site\": 707, \"mutant\": \"T\", \"escape\": -0.036485436469908074, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": 0.0623, \"times_seen\": 8.0}, {\"site\": 707, \"mutant\": \"V\", \"escape\": -0.012355006986187423, \"epitope\": \"epitope 1\", \"reference_site\": \"710\", \"functional effect\": -0.2966, \"times_seen\": 5.0}, {\"site\": 708, \"mutant\": \"A\", \"escape\": 0.02315395679977233, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.6379, \"times_seen\": 7.0}, {\"site\": 708, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -0.8443, \"times_seen\": null}, {\"site\": 708, \"mutant\": \"F\", \"escape\": -0.006859459203338155, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -2.7301, \"times_seen\": 1.0}, {\"site\": 708, \"mutant\": \"G\", \"escape\": -0.05579102576469302, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -0.1169, \"times_seen\": 8.0}, {\"site\": 708, \"mutant\": \"I\", \"escape\": -0.011596153424864114, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.7186, \"times_seen\": 2.0}, {\"site\": 708, \"mutant\": \"K\", \"escape\": -0.0032700498491838176, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -2.5205, \"times_seen\": 1.0}, {\"site\": 708, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -2.9811, \"times_seen\": null}, {\"site\": 708, \"mutant\": \"N\", \"escape\": -0.06345168453099963, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.7215, \"times_seen\": 17.0}, {\"site\": 708, \"mutant\": \"R\", \"escape\": -0.010028185447266719, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.0857, \"times_seen\": 4.0}, {\"site\": 708, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 708, \"mutant\": \"T\", \"escape\": -0.01614282494912684, \"epitope\": \"epitope 1\", \"reference_site\": \"711\", \"functional effect\": -1.4944, \"times_seen\": 6.0}, {\"site\": 709, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 709, \"mutant\": \"L\", \"escape\": -0.0038443785711579125, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -1.5703, \"times_seen\": 1.0}, {\"site\": 709, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -3.249, \"times_seen\": null}, {\"site\": 709, \"mutant\": \"S\", \"escape\": 0.0009874194200943545, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -2.8567, \"times_seen\": 1.0}, {\"site\": 709, \"mutant\": \"T\", \"escape\": -0.01874702597573485, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -0.9693, \"times_seen\": 9.0}, {\"site\": 709, \"mutant\": \"V\", \"escape\": -0.015153486088431244, \"epitope\": \"epitope 1\", \"reference_site\": \"712\", \"functional effect\": -1.6063, \"times_seen\": 26.0}, {\"site\": 710, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 710, \"mutant\": \"D\", \"escape\": 0.054254571519434226, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -0.4359, \"times_seen\": 16.0}, {\"site\": 710, \"mutant\": \"G\", \"escape\": 0.012207569024657127, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -0.5815, \"times_seen\": 1.0}, {\"site\": 710, \"mutant\": \"P\", \"escape\": 0.0016426147170748476, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.866, \"times_seen\": 1.0}, {\"site\": 710, \"mutant\": \"Q\", \"escape\": 0.023696529449635604, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -0.2114, \"times_seen\": 6.0}, {\"site\": 710, \"mutant\": \"S\", \"escape\": 0.017963598210893886, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.0541, \"times_seen\": 10.0}, {\"site\": 710, \"mutant\": \"T\", \"escape\": 0.002686082660682988, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.1178, \"times_seen\": 11.0}, {\"site\": 710, \"mutant\": \"V\", \"escape\": -0.00879130904253882, \"epitope\": \"epitope 1\", \"reference_site\": \"713\", \"functional effect\": -2.4829, \"times_seen\": 2.0}, {\"site\": 711, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 711, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -3.2101, \"times_seen\": null}, {\"site\": 711, \"mutant\": \"M\", \"escape\": -0.0030198902378815325, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -2.012, \"times_seen\": 1.0}, {\"site\": 711, \"mutant\": \"T\", \"escape\": -0.0018666871195398128, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -2.5336, \"times_seen\": 1.0}, {\"site\": 711, \"mutant\": \"V\", \"escape\": 0.022661189546111876, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": 0.4407, \"times_seen\": 11.0}, {\"site\": 711, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"714\", \"functional effect\": -2.9601, \"times_seen\": null}, {\"site\": 712, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 712, \"mutant\": \"L\", \"escape\": -0.0036814483609719723, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.8988, \"times_seen\": 2.0}, {\"site\": 712, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 712, \"mutant\": \"Q\", \"escape\": -0.0029815836146304133, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.9818, \"times_seen\": 1.0}, {\"site\": 712, \"mutant\": \"S\", \"escape\": 0.00856422156853133, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.0135, \"times_seen\": 10.0}, {\"site\": 712, \"mutant\": \"T\", \"escape\": 0.0018267045397835535, \"epitope\": \"epitope 1\", \"reference_site\": \"715\", \"functional effect\": -2.5409, \"times_seen\": 1.0}, {\"site\": 713, \"mutant\": \"*\", \"escape\": -0.002333840259900389, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.766, \"times_seen\": 3.0}, {\"site\": 713, \"mutant\": \"A\", \"escape\": -0.004105182941738253, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.3536, \"times_seen\": 42.0}, {\"site\": 713, \"mutant\": \"C\", \"escape\": -0.06166350749524444, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.1522, \"times_seen\": 28.0}, {\"site\": 713, \"mutant\": \"D\", \"escape\": -0.0063055034620520325, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.9938, \"times_seen\": 2.0}, {\"site\": 713, \"mutant\": \"E\", \"escape\": -0.018926129948742706, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.7254, \"times_seen\": 7.0}, {\"site\": 713, \"mutant\": \"F\", \"escape\": 0.0053074953821839405, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.8224, \"times_seen\": 9.0}, {\"site\": 713, \"mutant\": \"G\", \"escape\": -0.02727200345393089, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.142, \"times_seen\": 27.0}, {\"site\": 713, \"mutant\": \"H\", \"escape\": -0.06017869488892423, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.9137, \"times_seen\": 22.0}, {\"site\": 713, \"mutant\": \"I\", \"escape\": 0.04294250193621467, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.3512, \"times_seen\": 32.0}, {\"site\": 713, \"mutant\": \"K\", \"escape\": -0.02972620065831531, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.6421, \"times_seen\": 12.0}, {\"site\": 713, \"mutant\": \"L\", \"escape\": -0.05342276261630031, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": 0.1647, \"times_seen\": 50.0}, {\"site\": 713, \"mutant\": \"M\", \"escape\": -0.020503567100815166, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": 0.1258, \"times_seen\": 8.0}, {\"site\": 713, \"mutant\": \"N\", \"escape\": 0.020701582896032092, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -1.3337, \"times_seen\": 16.0}, {\"site\": 713, \"mutant\": \"P\", \"escape\": -0.010607827955388033, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.6193, \"times_seen\": 2.0}, {\"site\": 713, \"mutant\": \"Q\", \"escape\": -0.017314608142157892, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.5219, \"times_seen\": 19.0}, {\"site\": 713, \"mutant\": \"R\", \"escape\": 0.002396542289137958, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.2702, \"times_seen\": 54.0}, {\"site\": 713, \"mutant\": \"S\", \"escape\": 0.3170123791038111, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -0.3731, \"times_seen\": 75.0}, {\"site\": 713, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 713, \"mutant\": \"V\", \"escape\": 0.060389799085921306, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.65, \"times_seen\": 12.0}, {\"site\": 713, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.874, \"times_seen\": null}, {\"site\": 713, \"mutant\": \"Y\", \"escape\": -0.008525042520820893, \"epitope\": \"epitope 1\", \"reference_site\": \"716\", \"functional effect\": -2.5844, \"times_seen\": 3.0}, {\"site\": 714, \"mutant\": \"D\", \"escape\": -0.009472764122485705, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.3437, \"times_seen\": 4.0}, {\"site\": 714, \"mutant\": \"H\", \"escape\": 0.012187553388122472, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.098, \"times_seen\": 7.0}, {\"site\": 714, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -1.1916, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"K\", \"escape\": -0.010733239870296219, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.5413, \"times_seen\": 6.0}, {\"site\": 714, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -3.1123, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"S\", \"escape\": -0.029043859452059794, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -1.7257, \"times_seen\": 18.0}, {\"site\": 714, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -2.0513, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"Y\", \"escape\": 0.0051582054185937715, \"epitope\": \"epitope 1\", \"reference_site\": \"717\", \"functional effect\": -1.0141, \"times_seen\": 7.0}, {\"site\": 715, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -2.8163, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -3.1152, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"S\", \"escape\": 0.01565563023250674, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -2.6831, \"times_seen\": 1.0}, {\"site\": 715, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"Y\", \"escape\": -0.005258571658184479, \"epitope\": \"epitope 1\", \"reference_site\": \"718\", \"functional effect\": -2.4214, \"times_seen\": 1.0}, {\"site\": 716, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 716, \"mutant\": \"A\", \"escape\": -0.0026776142317037734, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -2.2291, \"times_seen\": 2.0}, {\"site\": 716, \"mutant\": \"I\", \"escape\": -0.030684338599883607, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -2.5731, \"times_seen\": 9.0}, {\"site\": 716, \"mutant\": \"N\", \"escape\": 0.025340444551452578, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -1.5682, \"times_seen\": 12.0}, {\"site\": 716, \"mutant\": \"S\", \"escape\": 0.06476523752365335, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": -0.1762, \"times_seen\": 47.0}, {\"site\": 716, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"719\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"L\", \"escape\": 0.000218358102194978, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.3054, \"times_seen\": 1.0}, {\"site\": 717, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -2.6514, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -3.0739, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"T\", \"escape\": -0.00272496981819977, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.6882, \"times_seen\": 1.0}, {\"site\": 717, \"mutant\": \"V\", \"escape\": 0.030055488206725146, \"epitope\": \"epitope 1\", \"reference_site\": \"720\", \"functional effect\": -1.9977, \"times_seen\": 5.0}, {\"site\": 718, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.482, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"F\", \"escape\": 0.007240441491617189, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -1.3676, \"times_seen\": 4.0}, {\"site\": 718, \"mutant\": \"G\", \"escape\": -0.0055752426780033715, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.8207, \"times_seen\": 2.0}, {\"site\": 718, \"mutant\": \"I\", \"escape\": -0.0034802942395592445, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -2.3019, \"times_seen\": 1.0}, {\"site\": 718, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -1.6494, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"P\", \"escape\": -0.006436035581430702, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -2.8793, \"times_seen\": 2.0}, {\"site\": 718, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -0.2213, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"T\", \"escape\": 0.007865967533096317, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 718, \"mutant\": \"Y\", \"escape\": -0.002921993047265685, \"epitope\": \"epitope 1\", \"reference_site\": \"721\", \"functional effect\": -1.6519, \"times_seen\": 3.0}, {\"site\": 719, \"mutant\": \"A\", \"escape\": 0.0015812401682566651, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -1.1452, \"times_seen\": 1.0}, {\"site\": 719, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -1.8183, \"times_seen\": null}, {\"site\": 719, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -2.9973, \"times_seen\": null}, {\"site\": 719, \"mutant\": \"F\", \"escape\": 0.0019820100111131015, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -2.3651, \"times_seen\": 1.0}, {\"site\": 719, \"mutant\": \"I\", \"escape\": 0.7266613621154978, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -0.1681, \"times_seen\": 7.0}, {\"site\": 719, \"mutant\": \"L\", \"escape\": 0.002836667237259023, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -1.12, \"times_seen\": 1.0}, {\"site\": 719, \"mutant\": \"M\", \"escape\": -0.010926757636828205, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -0.9729, \"times_seen\": 5.0}, {\"site\": 719, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": -2.8552, \"times_seen\": null}, {\"site\": 719, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"722\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 720, \"mutant\": \"A\", \"escape\": -0.024450266973660817, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": 0.1971, \"times_seen\": 5.0}, {\"site\": 720, \"mutant\": \"I\", \"escape\": -0.045024970014327544, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -0.552, \"times_seen\": 21.0}, {\"site\": 720, \"mutant\": \"N\", \"escape\": -0.00359148788086554, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": 0.3561, \"times_seen\": 4.0}, {\"site\": 720, \"mutant\": \"P\", \"escape\": -0.003621496594338772, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -1.8336, \"times_seen\": 1.0}, {\"site\": 720, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -0.2352, \"times_seen\": null}, {\"site\": 720, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 720, \"mutant\": \"V\", \"escape\": -0.004798208699233431, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -0.1125, \"times_seen\": 2.0}, {\"site\": 720, \"mutant\": \"Y\", \"escape\": -0.00379338553497803, \"epitope\": \"epitope 1\", \"reference_site\": \"723\", \"functional effect\": -1.4441, \"times_seen\": 1.0}, {\"site\": 721, \"mutant\": \"A\", \"escape\": 0.016935052094812643, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 721, \"mutant\": \"I\", \"escape\": 0.12116776195314378, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.3543, \"times_seen\": 22.0}, {\"site\": 721, \"mutant\": \"K\", \"escape\": -0.006967303089117164, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": 0.106, \"times_seen\": 2.0}, {\"site\": 721, \"mutant\": \"P\", \"escape\": 0.0004593092515466432, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.394, \"times_seen\": 1.0}, {\"site\": 721, \"mutant\": \"S\", \"escape\": -0.000506702465414695, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": -0.3071, \"times_seen\": 16.0}, {\"site\": 721, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"724\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -2.9082, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"D\", \"escape\": -0.017566188868880676, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": 0.0546, \"times_seen\": 4.0}, {\"site\": 722, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -3.0518, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -3.1332, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"725\", \"functional effect\": -2.8455, \"times_seen\": null}, {\"site\": 723, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 723, \"mutant\": \"K\", \"escape\": 0.003586614264138213, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 723, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": -2.682, \"times_seen\": null}, {\"site\": 723, \"mutant\": \"T\", \"escape\": 0.3369707367018433, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": 0.3018, \"times_seen\": 8.0}, {\"site\": 723, \"mutant\": \"V\", \"escape\": 0.008265287087752253, \"epitope\": \"epitope 1\", \"reference_site\": \"726\", \"functional effect\": -0.9196, \"times_seen\": 4.0}, {\"site\": 724, \"mutant\": \"I\", \"escape\": 0.021800991732224915, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": 0.0311, \"times_seen\": 4.0}, {\"site\": 724, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 724, \"mutant\": \"M\", \"escape\": -0.01545171738848566, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -0.4216, \"times_seen\": 5.0}, {\"site\": 724, \"mutant\": \"P\", \"escape\": -0.004845618424718102, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -2.1136, \"times_seen\": 2.0}, {\"site\": 724, \"mutant\": \"Q\", \"escape\": 0.04908996999613294, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -1.2101, \"times_seen\": 4.0}, {\"site\": 724, \"mutant\": \"V\", \"escape\": -0.000988710244802542, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -0.4228, \"times_seen\": 1.0}, {\"site\": 724, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"727\", \"functional effect\": -2.2196, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -2.4798, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"L\", \"escape\": -0.022859477272953788, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -2.5579, \"times_seen\": 2.0}, {\"site\": 725, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -2.37, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -1.6758, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"S\", \"escape\": 0.009813097731142622, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -1.3273, \"times_seen\": 19.0}, {\"site\": 725, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"728\", \"functional effect\": -0.7129, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"A\", \"escape\": -0.01143133363625171, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": 0.3624, \"times_seen\": 1.0}, {\"site\": 726, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"E\", \"escape\": -0.011582521320343517, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.8092, \"times_seen\": 1.0}, {\"site\": 726, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.8622, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"M\", \"escape\": -0.4197478892183408, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": -2.6593, \"times_seen\": 4.0}, {\"site\": 726, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"729\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": 0.4189, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"C\", \"escape\": -0.002710315399560475, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.3591, \"times_seen\": 1.0}, {\"site\": 727, \"mutant\": \"F\", \"escape\": -0.023701586614310037, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.2728, \"times_seen\": 20.0}, {\"site\": 727, \"mutant\": \"G\", \"escape\": 0.0009349390178039224, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -3.0775, \"times_seen\": 2.0}, {\"site\": 727, \"mutant\": \"I\", \"escape\": 0.017909285352156096, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.6208, \"times_seen\": 2.0}, {\"site\": 727, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.1244, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"N\", \"escape\": 0.0006393261561953065, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.1699, \"times_seen\": 3.0}, {\"site\": 727, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -1.0604, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"R\", \"escape\": -0.0035515591812678425, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -1.1008, \"times_seen\": 1.0}, {\"site\": 727, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"T\", \"escape\": 0.005867713620661893, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -0.5495, \"times_seen\": 2.0}, {\"site\": 727, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"730\", \"functional effect\": -2.4419, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"I\", \"escape\": -0.21378529430410526, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -1.1321, \"times_seen\": 36.0}, {\"site\": 728, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -2.606, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"L\", \"escape\": 0.7437111029946146, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 728, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"T\", \"escape\": 0.0016322825368742626, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -2.2466, \"times_seen\": 5.0}, {\"site\": 728, \"mutant\": \"V\", \"escape\": 0.012756802339144563, \"epitope\": \"epitope 1\", \"reference_site\": \"731\", \"functional effect\": -1.9343, \"times_seen\": 7.0}, {\"site\": 729, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 729, \"mutant\": \"A\", \"escape\": -0.012566570467993386, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.2513, \"times_seen\": 37.0}, {\"site\": 729, \"mutant\": \"I\", \"escape\": 0.1063951736239534, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.2091, \"times_seen\": 44.0}, {\"site\": 729, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 729, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": -2.9597, \"times_seen\": null}, {\"site\": 729, \"mutant\": \"P\", \"escape\": -0.012166388638305851, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 729, \"mutant\": \"S\", \"escape\": -0.04610003305434679, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.2056, \"times_seen\": 32.0}, {\"site\": 729, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"732\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"E\", \"escape\": -0.0034762384559112736, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -2.8693, \"times_seen\": 1.0}, {\"site\": 730, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -3.1325, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"Q\", \"escape\": -0.0069752093712292075, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -2.9305, \"times_seen\": 1.0}, {\"site\": 730, \"mutant\": \"R\", \"escape\": -0.13214568282742542, \"epitope\": \"epitope 1\", \"reference_site\": \"733\", \"functional effect\": -0.7708, \"times_seen\": 18.0}, {\"site\": 731, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 731, \"mutant\": \"A\", \"escape\": -0.03495453071332299, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -0.4737, \"times_seen\": 13.0}, {\"site\": 731, \"mutant\": \"H\", \"escape\": -0.011927385126343776, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -0.9347, \"times_seen\": 4.0}, {\"site\": 731, \"mutant\": \"I\", \"escape\": 0.014624948433446819, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": 0.2248, \"times_seen\": 32.0}, {\"site\": 731, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -2.9745, \"times_seen\": null}, {\"site\": 731, \"mutant\": \"N\", \"escape\": -0.00771583649457923, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -2.7603, \"times_seen\": 2.0}, {\"site\": 731, \"mutant\": \"S\", \"escape\": -0.005057953921313432, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": -1.162, \"times_seen\": 1.0}, {\"site\": 731, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"734\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"A\", \"escape\": -0.07360760816754079, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.0825, \"times_seen\": 28.0}, {\"site\": 732, \"mutant\": \"F\", \"escape\": -0.020924907680234455, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.7428, \"times_seen\": 6.0}, {\"site\": 732, \"mutant\": \"I\", \"escape\": -0.006498652783917935, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -1.1909, \"times_seen\": 3.0}, {\"site\": 732, \"mutant\": \"L\", \"escape\": 0.1330854645876107, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -1.0983, \"times_seen\": 20.0}, {\"site\": 732, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -2.7322, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"Q\", \"escape\": -0.008334337310997891, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.2029, \"times_seen\": 5.0}, {\"site\": 732, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": 0.6738, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"Y\", \"escape\": -0.009905845551270267, \"epitope\": \"epitope 1\", \"reference_site\": \"735\", \"functional effect\": -0.4477, \"times_seen\": 3.0}, {\"site\": 733, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -1.6969, \"times_seen\": null}, {\"site\": 733, \"mutant\": \"I\", \"escape\": -0.015586007009503687, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -0.0938, \"times_seen\": 9.0}, {\"site\": 733, \"mutant\": \"L\", \"escape\": 0.004796958682669604, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -1.4082, \"times_seen\": 4.0}, {\"site\": 733, \"mutant\": \"M\", \"escape\": -0.005285367702656804, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -1.4028, \"times_seen\": 4.0}, {\"site\": 733, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 733, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"736\", \"functional effect\": -2.9548, \"times_seen\": null}, {\"site\": 734, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 734, \"mutant\": \"E\", \"escape\": -0.02240069106892352, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.017, \"times_seen\": 20.0}, {\"site\": 734, \"mutant\": \"G\", \"escape\": -0.01267377311291991, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.6831, \"times_seen\": 5.0}, {\"site\": 734, \"mutant\": \"H\", \"escape\": -0.0005206465021369214, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.036, \"times_seen\": 1.0}, {\"site\": 734, \"mutant\": \"N\", \"escape\": -0.018374838248598622, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -2.4426, \"times_seen\": 5.0}, {\"site\": 734, \"mutant\": \"Q\", \"escape\": 0.0744581367648725, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.5423, \"times_seen\": 4.0}, {\"site\": 734, \"mutant\": \"V\", \"escape\": -0.012828602627259711, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -1.4984, \"times_seen\": 5.0}, {\"site\": 734, \"mutant\": \"Y\", \"escape\": -0.0030061379040588043, \"epitope\": \"epitope 1\", \"reference_site\": \"737\", \"functional effect\": -0.4777, \"times_seen\": 7.0}, {\"site\": 735, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.9813, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"F\", \"escape\": 0.0033816593186977344, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.5456, \"times_seen\": 4.0}, {\"site\": 735, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.9196, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"Y\", \"escape\": -0.015420289389366465, \"epitope\": \"epitope 1\", \"reference_site\": \"738\", \"functional effect\": -2.4725, \"times_seen\": 4.0}, {\"site\": 736, \"mutant\": \"A\", \"escape\": -0.011524268217062305, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": 0.0824, \"times_seen\": 6.0}, {\"site\": 736, \"mutant\": \"I\", \"escape\": -0.15943612083433087, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.1671, \"times_seen\": 39.0}, {\"site\": 736, \"mutant\": \"K\", \"escape\": -0.004737535467852241, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.4855, \"times_seen\": 1.0}, {\"site\": 736, \"mutant\": \"L\", \"escape\": 0.008833309248169146, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.0817, \"times_seen\": 3.0}, {\"site\": 736, \"mutant\": \"S\", \"escape\": -0.004272873664583486, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": -0.0087, \"times_seen\": 5.0}, {\"site\": 736, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"739\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 737, \"mutant\": \"F\", \"escape\": 0.0012855257949767418, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.2664, \"times_seen\": 3.0}, {\"site\": 737, \"mutant\": \"I\", \"escape\": 0.035277886109254426, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.4403, \"times_seen\": 25.0}, {\"site\": 737, \"mutant\": \"K\", \"escape\": -0.0025852280083076993, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.0781, \"times_seen\": 4.0}, {\"site\": 737, \"mutant\": \"L\", \"escape\": -0.025547814673181672, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.9326, \"times_seen\": 6.0}, {\"site\": 737, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 737, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 737, \"mutant\": \"S\", \"escape\": -0.821607922806616, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.3955, \"times_seen\": 2.0}, {\"site\": 737, \"mutant\": \"T\", \"escape\": -0.00022072818301218573, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.0225, \"times_seen\": 6.0}, {\"site\": 737, \"mutant\": \"V\", \"escape\": -0.019516782746509434, \"epitope\": \"epitope 1\", \"reference_site\": \"740\", \"functional effect\": -0.2248, \"times_seen\": 8.0}, {\"site\": 738, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.5015, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -1.5617, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"H\", \"escape\": -0.007812124625626634, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.7764, \"times_seen\": 2.0}, {\"site\": 738, \"mutant\": \"N\", \"escape\": -0.0024319517816702796, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.4574, \"times_seen\": 1.0}, {\"site\": 738, \"mutant\": \"V\", \"escape\": 0.009769390837627307, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": -2.8876, \"times_seen\": 4.0}, {\"site\": 738, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"741\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"L\", \"escape\": -0.8180177511258102, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -0.1766, \"times_seen\": 6.0}, {\"site\": 739, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -3.0936, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"V\", \"escape\": -0.0245956481472353, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": 0.1886, \"times_seen\": 6.0}, {\"site\": 739, \"mutant\": \"Y\", \"escape\": -0.01917671873843008, \"epitope\": \"epitope 1\", \"reference_site\": \"742\", \"functional effect\": -2.1587, \"times_seen\": 1.0}, {\"site\": 740, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -0.6647, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -3.0343, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -2.8525, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -3.0053, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"R\", \"escape\": -0.014462666329709519, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -2.6612, \"times_seen\": 4.0}, {\"site\": 740, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -3.052, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"743\", \"functional effect\": -2.6502, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -2.6347, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": 0.4254, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"D\", \"escape\": -0.07818485457342017, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -1.9342, \"times_seen\": 3.0}, {\"site\": 741, \"mutant\": \"E\", \"escape\": 0.0185260609450213, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -0.6324, \"times_seen\": 12.0}, {\"site\": 741, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"Q\", \"escape\": -0.03010690554828606, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -0.8634, \"times_seen\": 10.0}, {\"site\": 741, \"mutant\": \"R\", \"escape\": -0.025158635616359264, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -1.8853, \"times_seen\": 8.0}, {\"site\": 741, \"mutant\": \"S\", \"escape\": -0.0038024173326237265, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -0.4687, \"times_seen\": 1.0}, {\"site\": 741, \"mutant\": \"V\", \"escape\": 0.008171423058934419, \"epitope\": \"epitope 1\", \"reference_site\": \"744\", \"functional effect\": -2.1101, \"times_seen\": 2.0}, {\"site\": 742, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 742, \"mutant\": \"A\", \"escape\": -0.009899539693270449, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -0.381, \"times_seen\": 4.0}, {\"site\": 742, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 742, \"mutant\": \"E\", \"escape\": -0.025979586226369776, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -1.2556, \"times_seen\": 9.0}, {\"site\": 742, \"mutant\": \"G\", \"escape\": -0.011992216348051844, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -0.5194, \"times_seen\": 11.0}, {\"site\": 742, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -1.1698, \"times_seen\": null}, {\"site\": 742, \"mutant\": \"N\", \"escape\": -0.002942587367771898, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -2.9882, \"times_seen\": 1.0}, {\"site\": 742, \"mutant\": \"Y\", \"escape\": 0.01080594685143142, \"epitope\": \"epitope 1\", \"reference_site\": \"745\", \"functional effect\": -0.4782, \"times_seen\": 4.0}, {\"site\": 743, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 743, \"mutant\": \"C\", \"escape\": -0.005652339090314821, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": 0.0849, \"times_seen\": 2.0}, {\"site\": 743, \"mutant\": \"G\", \"escape\": 0.02217033664071543, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -2.1692, \"times_seen\": 3.0}, {\"site\": 743, \"mutant\": \"I\", \"escape\": -0.03256223282383209, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -0.953, \"times_seen\": 10.0}, {\"site\": 743, \"mutant\": \"N\", \"escape\": 0.1828293921832935, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -0.334, \"times_seen\": 31.0}, {\"site\": 743, \"mutant\": \"R\", \"escape\": -0.0028510922921039165, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -2.1849, \"times_seen\": 1.0}, {\"site\": 743, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 743, \"mutant\": \"T\", \"escape\": -0.002692372146451101, \"epitope\": \"epitope 1\", \"reference_site\": \"746\", \"functional effect\": -0.7858, \"times_seen\": 1.0}, {\"site\": 744, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 744, \"mutant\": \"A\", \"escape\": -0.011943170156010392, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.3931, \"times_seen\": 11.0}, {\"site\": 744, \"mutant\": \"I\", \"escape\": 0.795334009408156, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.2878, \"times_seen\": 22.0}, {\"site\": 744, \"mutant\": \"K\", \"escape\": -0.002119561794240673, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.1667, \"times_seen\": 2.0}, {\"site\": 744, \"mutant\": \"N\", \"escape\": -0.00073475630766969, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.1635, \"times_seen\": 3.0}, {\"site\": 744, \"mutant\": \"P\", \"escape\": 0.010403508660479906, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.0825, \"times_seen\": 4.0}, {\"site\": 744, \"mutant\": \"S\", \"escape\": 0.013559828454335728, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 744, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 744, \"mutant\": \"V\", \"escape\": -0.01020266610741479, \"epitope\": \"epitope 1\", \"reference_site\": \"747\", \"functional effect\": -0.047, \"times_seen\": 4.0}, {\"site\": 745, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -2.9623, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.4818, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"D\", \"escape\": 0.05015264442677513, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.1863, \"times_seen\": 8.0}, {\"site\": 745, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.1913, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"K\", \"escape\": 1.252633411203604, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.4162, \"times_seen\": 12.0}, {\"site\": 745, \"mutant\": \"Q\", \"escape\": 0.07316870325340293, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.5398, \"times_seen\": 13.0}, {\"site\": 745, \"mutant\": \"R\", \"escape\": 0.004919496167733923, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.8477, \"times_seen\": 5.0}, {\"site\": 745, \"mutant\": \"V\", \"escape\": 0.01656017517161403, \"epitope\": \"epitope 1\", \"reference_site\": \"748\", \"functional effect\": -0.5605, \"times_seen\": 11.0}, {\"site\": 746, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.0745, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"F\", \"escape\": -0.0018759544953936608, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.2959, \"times_seen\": 1.0}, {\"site\": 746, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.9607, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"L\", \"escape\": -0.00045147138541207015, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.1098, \"times_seen\": 1.0}, {\"site\": 746, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.0024, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.8875, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"Y\", \"escape\": 0.012914491224275916, \"epitope\": \"epitope 1\", \"reference_site\": \"749\", \"functional effect\": -2.3491, \"times_seen\": 5.0}, {\"site\": 747, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 747, \"mutant\": \"C\", \"escape\": -0.009342361384977932, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -1.0003, \"times_seen\": 13.0}, {\"site\": 747, \"mutant\": \"G\", \"escape\": 0.049577509472603185, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": 0.2269, \"times_seen\": 79.0}, {\"site\": 747, \"mutant\": \"I\", \"escape\": -0.05820919767611924, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.3044, \"times_seen\": 16.0}, {\"site\": 747, \"mutant\": \"N\", \"escape\": -0.025801059464943186, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.0421, \"times_seen\": 31.0}, {\"site\": 747, \"mutant\": \"R\", \"escape\": -0.02669533275707028, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.1217, \"times_seen\": 13.0}, {\"site\": 747, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 747, \"mutant\": \"T\", \"escape\": -0.006050838080986991, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": 0.0836, \"times_seen\": 20.0}, {\"site\": 747, \"mutant\": \"Y\", \"escape\": -0.020353218036113927, \"epitope\": \"epitope 1\", \"reference_site\": \"750\", \"functional effect\": -0.0658, \"times_seen\": 14.0}, {\"site\": 748, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 748, \"mutant\": \"D\", \"escape\": -0.2632983358772517, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0264, \"times_seen\": 44.0}, {\"site\": 748, \"mutant\": \"F\", \"escape\": 0.020334247998317234, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": -0.0541, \"times_seen\": 2.0}, {\"site\": 748, \"mutant\": \"I\", \"escape\": 0.02353325464255248, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": -0.2394, \"times_seen\": 5.0}, {\"site\": 748, \"mutant\": \"K\", \"escape\": 0.02705907786394538, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.2424, \"times_seen\": 9.0}, {\"site\": 748, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 748, \"mutant\": \"S\", \"escape\": -0.005975719871330656, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0683, \"times_seen\": 7.0}, {\"site\": 748, \"mutant\": \"T\", \"escape\": 0.0112584878150122, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0901, \"times_seen\": 9.0}, {\"site\": 748, \"mutant\": \"Y\", \"escape\": -0.025982855638140224, \"epitope\": \"epitope 1\", \"reference_site\": \"751\", \"functional effect\": 0.0153, \"times_seen\": 5.0}, {\"site\": 749, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 749, \"mutant\": \"F\", \"escape\": -0.013829584144662106, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -2.0375, \"times_seen\": 6.0}, {\"site\": 749, \"mutant\": \"I\", \"escape\": 0.008456091873472972, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -1.0664, \"times_seen\": 3.0}, {\"site\": 749, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 749, \"mutant\": \"M\", \"escape\": 0.003288258011524178, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.0729, \"times_seen\": 12.0}, {\"site\": 749, \"mutant\": \"P\", \"escape\": -0.4983574585524083, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -2.6643, \"times_seen\": 10.0}, {\"site\": 749, \"mutant\": \"Q\", \"escape\": -0.009675410295064009, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.3644, \"times_seen\": 2.0}, {\"site\": 749, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.0322, \"times_seen\": null}, {\"site\": 749, \"mutant\": \"V\", \"escape\": -0.010716054508324014, \"epitope\": \"epitope 1\", \"reference_site\": \"752\", \"functional effect\": -0.776, \"times_seen\": 6.0}, {\"site\": 750, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 750, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -2.9731, \"times_seen\": null}, {\"site\": 750, \"mutant\": \"F\", \"escape\": 0.018507098095575308, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.7661, \"times_seen\": 6.0}, {\"site\": 750, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 750, \"mutant\": \"M\", \"escape\": 0.016917472400666624, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.673, \"times_seen\": 2.0}, {\"site\": 750, \"mutant\": \"P\", \"escape\": 0.02240332626535998, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -2.7073, \"times_seen\": 2.0}, {\"site\": 750, \"mutant\": \"Q\", \"escape\": -0.008852240633575623, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 750, \"mutant\": \"V\", \"escape\": -0.018399294110689694, \"epitope\": \"epitope 1\", \"reference_site\": \"753\", \"functional effect\": -0.3226, \"times_seen\": 12.0}, {\"site\": 751, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 751, \"mutant\": \"C\", \"escape\": -0.0034920863240241666, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -0.4671, \"times_seen\": 1.0}, {\"site\": 751, \"mutant\": \"F\", \"escape\": 0.027731998780798146, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.0366, \"times_seen\": 76.0}, {\"site\": 751, \"mutant\": \"H\", \"escape\": 0.007711603400451653, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -2.891, \"times_seen\": 4.0}, {\"site\": 751, \"mutant\": \"I\", \"escape\": -0.05877942769609557, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": -0.0719, \"times_seen\": 24.0}, {\"site\": 751, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 751, \"mutant\": \"P\", \"escape\": 0.014377211034353571, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.1158, \"times_seen\": 12.0}, {\"site\": 751, \"mutant\": \"S\", \"escape\": 0.008915859292026224, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.0848, \"times_seen\": 5.0}, {\"site\": 751, \"mutant\": \"V\", \"escape\": -0.020809232612295257, \"epitope\": \"epitope 1\", \"reference_site\": \"754\", \"functional effect\": 0.1702, \"times_seen\": 8.0}, {\"site\": 752, \"mutant\": \"*\", \"escape\": -0.003277989833761576, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -2.2523, \"times_seen\": 1.0}, {\"site\": 752, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"A\", \"escape\": -0.009337556257377788, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.2403, \"times_seen\": 2.0}, {\"site\": 752, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.6948, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -0.9599, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"K\", \"escape\": 0.006719122633935337, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -1.4802, \"times_seen\": 3.0}, {\"site\": 752, \"mutant\": \"N\", \"escape\": 0.019826978688870605, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -1.0858, \"times_seen\": 5.0}, {\"site\": 752, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": -3.234, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"755\", \"functional effect\": 0.4155, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -3.0014, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"A\", \"escape\": -0.008078882654769907, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.943, \"times_seen\": 2.0}, {\"site\": 753, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.2583, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.0683, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"H\", \"escape\": -0.010122327368807388, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -2.4891, \"times_seen\": 6.0}, {\"site\": 753, \"mutant\": \"I\", \"escape\": -0.003913505235385449, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 753, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -0.7486, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"M\", \"escape\": -0.002276691929688238, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -2.9344, \"times_seen\": 1.0}, {\"site\": 753, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": -3.1031, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"756\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 754, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 754, \"mutant\": \"A\", \"escape\": -0.033752482309721686, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.7854, \"times_seen\": 7.0}, {\"site\": 754, \"mutant\": \"C\", \"escape\": -0.007271390037914976, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -2.8243, \"times_seen\": 1.0}, {\"site\": 754, \"mutant\": \"D\", \"escape\": -0.38504195563579774, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.0894, \"times_seen\": 58.0}, {\"site\": 754, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 754, \"mutant\": \"N\", \"escape\": -0.002611221811781416, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.9744, \"times_seen\": 7.0}, {\"site\": 754, \"mutant\": \"S\", \"escape\": 0.007154522522405106, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -1.7512, \"times_seen\": 5.0}, {\"site\": 754, \"mutant\": \"V\", \"escape\": -0.0026999593894663277, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -0.6318, \"times_seen\": 4.0}, {\"site\": 754, \"mutant\": \"W\", \"escape\": 0.022054887647912608, \"epitope\": \"epitope 1\", \"reference_site\": \"757\", \"functional effect\": -2.4308, \"times_seen\": 7.0}, {\"site\": 755, \"mutant\": \"A\", \"escape\": -0.017036961442976086, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.2737, \"times_seen\": 11.0}, {\"site\": 755, \"mutant\": \"F\", \"escape\": 0.054940269301818376, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.0587, \"times_seen\": 5.0}, {\"site\": 755, \"mutant\": \"G\", \"escape\": 0.011941029887495467, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.3216, \"times_seen\": 5.0}, {\"site\": 755, \"mutant\": \"I\", \"escape\": -0.00905828286589454, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.1119, \"times_seen\": 7.0}, {\"site\": 755, \"mutant\": \"P\", \"escape\": -0.031271188087404346, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.4627, \"times_seen\": 3.0}, {\"site\": 755, \"mutant\": \"Q\", \"escape\": -0.008265366254306027, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 755, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 755, \"mutant\": \"T\", \"escape\": 1.0559524397870947, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.1522, \"times_seen\": 15.0}, {\"site\": 755, \"mutant\": \"V\", \"escape\": -0.01418190160474428, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": 0.0004, \"times_seen\": 9.0}, {\"site\": 755, \"mutant\": \"Y\", \"escape\": 0.0005885056455151958, \"epitope\": \"epitope 1\", \"reference_site\": \"758\", \"functional effect\": -0.2785, \"times_seen\": 1.0}, {\"site\": 756, \"mutant\": \"C\", \"escape\": -0.0034070001896972374, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.9521, \"times_seen\": 1.0}, {\"site\": 756, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 756, \"mutant\": \"I\", \"escape\": 0.016708315456867833, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.2458, \"times_seen\": 7.0}, {\"site\": 756, \"mutant\": \"L\", \"escape\": -0.007598515393835494, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.2885, \"times_seen\": 9.0}, {\"site\": 756, \"mutant\": \"S\", \"escape\": 0.06775061399814201, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.2136, \"times_seen\": 15.0}, {\"site\": 756, \"mutant\": \"V\", \"escape\": -0.006208253506421532, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -1.5576, \"times_seen\": 2.0}, {\"site\": 756, \"mutant\": \"Y\", \"escape\": -0.006839713372977832, \"epitope\": \"epitope 1\", \"reference_site\": \"759\", \"functional effect\": -0.2353, \"times_seen\": 2.0}, {\"site\": 757, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.4519, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"F\", \"escape\": -0.004138203419623897, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -1.2855, \"times_seen\": 1.0}, {\"site\": 757, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.919, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -3.0579, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.6628, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -2.8402, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"Y\", \"escape\": -0.029004503495458446, \"epitope\": \"epitope 1\", \"reference_site\": \"760\", \"functional effect\": -1.6236, \"times_seen\": 5.0}, {\"site\": 758, \"mutant\": \"A\", \"escape\": -0.7793062999944932, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.1197, \"times_seen\": 47.0}, {\"site\": 758, \"mutant\": \"C\", \"escape\": -0.012220977168575205, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -1.0763, \"times_seen\": 5.0}, {\"site\": 758, \"mutant\": \"D\", \"escape\": 0.007822972309261088, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 758, \"mutant\": \"I\", \"escape\": -0.14225832380899717, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.1772, \"times_seen\": 71.0}, {\"site\": 758, \"mutant\": \"K\", \"escape\": -0.05289694726518503, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.2376, \"times_seen\": 9.0}, {\"site\": 758, \"mutant\": \"N\", \"escape\": 0.03010721520554718, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.1582, \"times_seen\": 6.0}, {\"site\": 758, \"mutant\": \"R\", \"escape\": -0.017591885867475846, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.1127, \"times_seen\": 10.0}, {\"site\": 758, \"mutant\": \"S\", \"escape\": -0.002962207707081072, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.0003, \"times_seen\": 5.0}, {\"site\": 758, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 758, \"mutant\": \"Y\", \"escape\": 0.004290286042422085, \"epitope\": \"epitope 1\", \"reference_site\": \"761\", \"functional effect\": -0.115, \"times_seen\": 15.0}, {\"site\": 759, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -1.8736, \"times_seen\": null}, {\"site\": 759, \"mutant\": \"H\", \"escape\": -0.008032062637364874, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -0.3831, \"times_seen\": 7.0}, {\"site\": 759, \"mutant\": \"K\", \"escape\": -0.020055950749613943, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -1.9731, \"times_seen\": 7.0}, {\"site\": 759, \"mutant\": \"L\", \"escape\": -0.010438262345638428, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -1.1412, \"times_seen\": 3.0}, {\"site\": 759, \"mutant\": \"N\", \"escape\": 0.03477337190747731, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": 0.3165, \"times_seen\": 10.0}, {\"site\": 759, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 759, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -0.5475, \"times_seen\": null}, {\"site\": 759, \"mutant\": \"T\", \"escape\": -0.009196669743271475, \"epitope\": \"epitope 1\", \"reference_site\": \"762\", \"functional effect\": -0.0864, \"times_seen\": 5.0}, {\"site\": 760, \"mutant\": \"F\", \"escape\": 0.01697774323728397, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -1.6237, \"times_seen\": 8.0}, {\"site\": 760, \"mutant\": \"H\", \"escape\": 0.0013311140939375296, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -0.6558, \"times_seen\": 1.0}, {\"site\": 760, \"mutant\": \"I\", \"escape\": -0.0007773994759401834, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -0.0134, \"times_seen\": 9.0}, {\"site\": 760, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 760, \"mutant\": \"M\", \"escape\": -0.0036263287229920324, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": 0.16, \"times_seen\": 7.0}, {\"site\": 760, \"mutant\": \"P\", \"escape\": -0.0031273434833645505, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -0.4704, \"times_seen\": 1.0}, {\"site\": 760, \"mutant\": \"S\", \"escape\": 0.016597707590622405, \"epitope\": \"epitope 1\", \"reference_site\": \"763\", \"functional effect\": -1.5481, \"times_seen\": 1.0}, {\"site\": 761, \"mutant\": \"*\", \"escape\": -0.012525210462070934, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -2.5877, \"times_seen\": 4.0}, {\"site\": 761, \"mutant\": \"A\", \"escape\": 0.4804126507540502, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.226, \"times_seen\": 37.0}, {\"site\": 761, \"mutant\": \"C\", \"escape\": -0.0323165292751556, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.6222, \"times_seen\": 14.0}, {\"site\": 761, \"mutant\": \"D\", \"escape\": -0.023455696526057737, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.3145, \"times_seen\": 12.0}, {\"site\": 761, \"mutant\": \"E\", \"escape\": 0.008118043383415954, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.8716, \"times_seen\": 17.0}, {\"site\": 761, \"mutant\": \"F\", \"escape\": -0.015848446751639083, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.4497, \"times_seen\": 5.0}, {\"site\": 761, \"mutant\": \"G\", \"escape\": -0.05489908179073948, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.2276, \"times_seen\": 38.0}, {\"site\": 761, \"mutant\": \"H\", \"escape\": -0.02270380341966717, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.085, \"times_seen\": 12.0}, {\"site\": 761, \"mutant\": \"I\", \"escape\": -0.014917168599223516, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -1.4162, \"times_seen\": 5.0}, {\"site\": 761, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 761, \"mutant\": \"L\", \"escape\": -0.19332383440257678, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.7349, \"times_seen\": 32.0}, {\"site\": 761, \"mutant\": \"M\", \"escape\": -0.022151063188181778, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.265, \"times_seen\": 20.0}, {\"site\": 761, \"mutant\": \"N\", \"escape\": -0.007422895016433634, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.6305, \"times_seen\": 35.0}, {\"site\": 761, \"mutant\": \"P\", \"escape\": 0.001854293116328937, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -2.9308, \"times_seen\": 6.0}, {\"site\": 761, \"mutant\": \"Q\", \"escape\": -0.04572289742839538, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": 0.3452, \"times_seen\": 23.0}, {\"site\": 761, \"mutant\": \"R\", \"escape\": -0.05611883850523024, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": 0.1124, \"times_seen\": 69.0}, {\"site\": 761, \"mutant\": \"S\", \"escape\": -1.1649708510233467, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.3048, \"times_seen\": 47.0}, {\"site\": 761, \"mutant\": \"T\", \"escape\": -0.061012686614858945, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.0973, \"times_seen\": 35.0}, {\"site\": 761, \"mutant\": \"V\", \"escape\": -0.003755037122376053, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.3854, \"times_seen\": 22.0}, {\"site\": 761, \"mutant\": \"W\", \"escape\": -0.013445739404364035, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.8069, \"times_seen\": 11.0}, {\"site\": 761, \"mutant\": \"Y\", \"escape\": 0.006026235772976555, \"epitope\": \"epitope 1\", \"reference_site\": \"764\", \"functional effect\": -0.3796, \"times_seen\": 12.0}, {\"site\": 762, \"mutant\": \"-\", \"escape\": -0.001417293274266497, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 762, \"mutant\": \"C\", \"escape\": -0.012202342635390344, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -1.5482, \"times_seen\": 4.0}, {\"site\": 762, \"mutant\": \"G\", \"escape\": 0.5807291161330874, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.2881, \"times_seen\": 27.0}, {\"site\": 762, \"mutant\": \"H\", \"escape\": 0.5665747006721763, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.9356, \"times_seen\": 4.0}, {\"site\": 762, \"mutant\": \"K\", \"escape\": -0.003226797163155639, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.0548, \"times_seen\": 9.0}, {\"site\": 762, \"mutant\": \"L\", \"escape\": 0.011632093705976515, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.5001, \"times_seen\": 12.0}, {\"site\": 762, \"mutant\": \"M\", \"escape\": -0.5109280763037483, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.2185, \"times_seen\": 1.0}, {\"site\": 762, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -2.6327, \"times_seen\": null}, {\"site\": 762, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -1.1381, \"times_seen\": null}, {\"site\": 762, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 762, \"mutant\": \"S\", \"escape\": -0.009526134185130148, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.495, \"times_seen\": 19.0}, {\"site\": 762, \"mutant\": \"V\", \"escape\": 0.036964053049755544, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.7384, \"times_seen\": 6.0}, {\"site\": 762, \"mutant\": \"W\", \"escape\": -0.0022783038977917764, \"epitope\": \"epitope 1\", \"reference_site\": \"765\", \"functional effect\": -0.9641, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"-\", \"escape\": -0.003059568101247374, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 763, \"mutant\": \"C\", \"escape\": 0.007880198988945479, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.9905, \"times_seen\": 2.0}, {\"site\": 763, \"mutant\": \"D\", \"escape\": 0.013437235025287516, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -1.6376, \"times_seen\": 8.0}, {\"site\": 763, \"mutant\": \"F\", \"escape\": -0.012363395260191716, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.6086, \"times_seen\": 3.0}, {\"site\": 763, \"mutant\": \"G\", \"escape\": -0.00380233952685746, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -1.5951, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"L\", \"escape\": 0.008306146983347152, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.3293, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"S\", \"escape\": -0.004668591903707849, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": 0.2056, \"times_seen\": 2.0}, {\"site\": 763, \"mutant\": \"T\", \"escape\": -0.1011725281855223, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.0657, \"times_seen\": 18.0}, {\"site\": 763, \"mutant\": \"V\", \"escape\": -0.013039110796888829, \"epitope\": \"epitope 1\", \"reference_site\": \"766\", \"functional effect\": -0.633, \"times_seen\": 11.0}, {\"site\": 764, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -3.2893, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -2.8309, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"M\", \"escape\": 0.0065070064986836595, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -0.3954, \"times_seen\": 6.0}, {\"site\": 764, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"Q\", \"escape\": -0.0029744781799569565, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -1.116, \"times_seen\": 1.0}, {\"site\": 764, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -3.2678, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"V\", \"escape\": -0.006270860582543128, \"epitope\": \"epitope 1\", \"reference_site\": \"767\", \"functional effect\": -2.3797, \"times_seen\": 2.0}, {\"site\": 765, \"mutant\": \"A\", \"escape\": 0.008272147708279446, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.8115, \"times_seen\": 11.0}, {\"site\": 765, \"mutant\": \"E\", \"escape\": -0.943586781984381, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 765, \"mutant\": \"H\", \"escape\": -0.0013819516461867358, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.697, \"times_seen\": 11.0}, {\"site\": 765, \"mutant\": \"I\", \"escape\": -0.5142224013328911, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.4963, \"times_seen\": 43.0}, {\"site\": 765, \"mutant\": \"K\", \"escape\": -0.028680615549234647, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -1.1789, \"times_seen\": 8.0}, {\"site\": 765, \"mutant\": \"N\", \"escape\": -0.015603034057176614, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": 0.1124, \"times_seen\": 70.0}, {\"site\": 765, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.6456, \"times_seen\": null}, {\"site\": 765, \"mutant\": \"S\", \"escape\": -0.023079050167178292, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": -0.4113, \"times_seen\": 7.0}, {\"site\": 765, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"768\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 766, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -2.8225, \"times_seen\": null}, {\"site\": 766, \"mutant\": \"A\", \"escape\": 0.05459821824337203, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.3442, \"times_seen\": 112.0}, {\"site\": 766, \"mutant\": \"C\", \"escape\": -0.8659584166434384, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.7485, \"times_seen\": 108.0}, {\"site\": 766, \"mutant\": \"D\", \"escape\": 0.1481446619540826, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2311, \"times_seen\": 125.0}, {\"site\": 766, \"mutant\": \"E\", \"escape\": -0.018732389658270395, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.1186, \"times_seen\": 55.0}, {\"site\": 766, \"mutant\": \"F\", \"escape\": 0.19022954275971193, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.4384, \"times_seen\": 57.0}, {\"site\": 766, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 766, \"mutant\": \"H\", \"escape\": 0.06783283282698956, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2743, \"times_seen\": 49.0}, {\"site\": 766, \"mutant\": \"I\", \"escape\": -0.002471436393940553, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.8515, \"times_seen\": 44.0}, {\"site\": 766, \"mutant\": \"K\", \"escape\": 0.01658804059625846, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.3583, \"times_seen\": 35.0}, {\"site\": 766, \"mutant\": \"L\", \"escape\": 0.20375469960220166, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.5519, \"times_seen\": 83.0}, {\"site\": 766, \"mutant\": \"M\", \"escape\": -0.03242136858881625, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.1667, \"times_seen\": 23.0}, {\"site\": 766, \"mutant\": \"N\", \"escape\": 0.03861605139177667, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2105, \"times_seen\": 79.0}, {\"site\": 766, \"mutant\": \"P\", \"escape\": 0.0032541438522577077, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -2.7401, \"times_seen\": 12.0}, {\"site\": 766, \"mutant\": \"Q\", \"escape\": -0.03747989542950355, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": 0.0564, \"times_seen\": 20.0}, {\"site\": 766, \"mutant\": \"R\", \"escape\": 0.07239272839203276, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2939, \"times_seen\": 212.0}, {\"site\": 766, \"mutant\": \"S\", \"escape\": -0.04679919903866822, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.2042, \"times_seen\": 153.0}, {\"site\": 766, \"mutant\": \"T\", \"escape\": -0.008216986388086352, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.6609, \"times_seen\": 65.0}, {\"site\": 766, \"mutant\": \"V\", \"escape\": 0.009696065332897894, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.8462, \"times_seen\": 148.0}, {\"site\": 766, \"mutant\": \"W\", \"escape\": -0.016307222314919496, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.3517, \"times_seen\": 39.0}, {\"site\": 766, \"mutant\": \"Y\", \"escape\": 0.20852180861805628, \"epitope\": \"epitope 1\", \"reference_site\": \"769\", \"functional effect\": -0.1698, \"times_seen\": 58.0}, {\"site\": 767, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 767, \"mutant\": \"L\", \"escape\": -0.009260856679062561, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.5587, \"times_seen\": 3.0}, {\"site\": 767, \"mutant\": \"M\", \"escape\": -0.009853735735742882, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.6704, \"times_seen\": 11.0}, {\"site\": 767, \"mutant\": \"N\", \"escape\": -0.003739514482644747, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.4593, \"times_seen\": 1.0}, {\"site\": 767, \"mutant\": \"T\", \"escape\": -0.004067306534982462, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -2.8362, \"times_seen\": 1.0}, {\"site\": 767, \"mutant\": \"V\", \"escape\": -0.0488204883077654, \"epitope\": \"epitope 1\", \"reference_site\": \"770\", \"functional effect\": -0.2712, \"times_seen\": 18.0}, {\"site\": 768, \"mutant\": \"*\", \"escape\": 0.01627733061474761, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.7602, \"times_seen\": 2.0}, {\"site\": 768, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 768, \"mutant\": \"C\", \"escape\": 0.028941063879308195, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -1.0503, \"times_seen\": 18.0}, {\"site\": 768, \"mutant\": \"D\", \"escape\": -0.0029340013956589196, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9103, \"times_seen\": 5.0}, {\"site\": 768, \"mutant\": \"E\", \"escape\": -0.006789651339924142, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.5854, \"times_seen\": 3.0}, {\"site\": 768, \"mutant\": \"F\", \"escape\": -0.0048433814366730665, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.4737, \"times_seen\": 1.0}, {\"site\": 768, \"mutant\": \"G\", \"escape\": 0.08115188320581944, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -0.4717, \"times_seen\": 47.0}, {\"site\": 768, \"mutant\": \"H\", \"escape\": -0.004809128727318938, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -3.0029, \"times_seen\": 1.0}, {\"site\": 768, \"mutant\": \"I\", \"escape\": -0.0076429311418821245, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.686, \"times_seen\": 2.0}, {\"site\": 768, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9716, \"times_seen\": null}, {\"site\": 768, \"mutant\": \"L\", \"escape\": -0.01047253169136093, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.7146, \"times_seen\": 3.0}, {\"site\": 768, \"mutant\": \"M\", \"escape\": -0.004649728562674287, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.8167, \"times_seen\": 1.0}, {\"site\": 768, \"mutant\": \"N\", \"escape\": -1.8048245883318619, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -0.1069, \"times_seen\": 19.0}, {\"site\": 768, \"mutant\": \"P\", \"escape\": 0.010995447556484962, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9758, \"times_seen\": 3.0}, {\"site\": 768, \"mutant\": \"Q\", \"escape\": -0.00557511763103494, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.2876, \"times_seen\": 2.0}, {\"site\": 768, \"mutant\": \"R\", \"escape\": -0.002174760536184471, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.9508, \"times_seen\": 4.0}, {\"site\": 768, \"mutant\": \"S\", \"escape\": -0.16632717585615156, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -0.4086, \"times_seen\": 66.0}, {\"site\": 768, \"mutant\": \"T\", \"escape\": -0.055665032417503646, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.2719, \"times_seen\": 15.0}, {\"site\": 768, \"mutant\": \"V\", \"escape\": 0.0524409700848544, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.6338, \"times_seen\": 10.0}, {\"site\": 768, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.493, \"times_seen\": null}, {\"site\": 768, \"mutant\": \"Y\", \"escape\": 0.014185309247402387, \"epitope\": \"epitope 1\", \"reference_site\": \"771\", \"functional effect\": -2.4901, \"times_seen\": 3.0}, {\"site\": 769, \"mutant\": \"A\", \"escape\": 0.00019372118393140296, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -1.0373, \"times_seen\": 5.0}, {\"site\": 769, \"mutant\": \"C\", \"escape\": 0.011976714572377395, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.8523, \"times_seen\": 7.0}, {\"site\": 769, \"mutant\": \"E\", \"escape\": -0.00408831794900461, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.8312, \"times_seen\": 2.0}, {\"site\": 769, \"mutant\": \"F\", \"escape\": 0.020769343307673598, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.7854, \"times_seen\": 5.0}, {\"site\": 769, \"mutant\": \"G\", \"escape\": 0.0006113882485058079, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -1.3317, \"times_seen\": 5.0}, {\"site\": 769, \"mutant\": \"I\", \"escape\": 0.01807642323230996, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.3216, \"times_seen\": 19.0}, {\"site\": 769, \"mutant\": \"L\", \"escape\": -0.02146282787547945, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.6707, \"times_seen\": 9.0}, {\"site\": 769, \"mutant\": \"M\", \"escape\": -0.06819613015182205, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": -0.6794, \"times_seen\": 21.0}, {\"site\": 769, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"772\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -2.9508, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"D\", \"escape\": -0.0018817360839492967, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -0.6339, \"times_seen\": 5.0}, {\"site\": 770, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"G\", \"escape\": 0.020361962141551417, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -1.584, \"times_seen\": 1.0}, {\"site\": 770, \"mutant\": \"K\", \"escape\": -0.0015591725216454976, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -2.1972, \"times_seen\": 3.0}, {\"site\": 770, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -1.329, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": 0.5283, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"773\", \"functional effect\": -3.2891, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"*\", \"escape\": -0.006778940166697411, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.8012, \"times_seen\": 3.0}, {\"site\": 771, \"mutant\": \"E\", \"escape\": -0.002623853061823227, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -3.2328, \"times_seen\": 1.0}, {\"site\": 771, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -1.5265, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"K\", \"escape\": 0.05879027363924959, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.8752, \"times_seen\": 2.0}, {\"site\": 771, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"P\", \"escape\": -0.0015127935777553003, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -0.3916, \"times_seen\": 1.0}, {\"site\": 771, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"R\", \"escape\": -0.010538984500101697, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.932, \"times_seen\": 2.0}, {\"site\": 771, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"774\", \"functional effect\": -2.9984, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"E\", \"escape\": -0.0033695765722841654, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -1.7483, \"times_seen\": 2.0}, {\"site\": 772, \"mutant\": \"G\", \"escape\": -0.0033109294289560354, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -1.6581, \"times_seen\": 1.0}, {\"site\": 772, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"N\", \"escape\": -0.010108607611673955, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.7155, \"times_seen\": 3.0}, {\"site\": 772, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.2599, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.568, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.4226, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"Y\", \"escape\": 0.01600293406305195, \"epitope\": \"epitope 1\", \"reference_site\": \"775\", \"functional effect\": -2.5069, \"times_seen\": 1.0}, {\"site\": 773, \"mutant\": \"E\", \"escape\": 0.0007172617158592446, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": -0.0735, \"times_seen\": 5.0}, {\"site\": 773, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 773, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 773, \"mutant\": \"M\", \"escape\": 0.00459708952147118, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 773, \"mutant\": \"N\", \"escape\": -0.017896432960084252, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": -1.9023, \"times_seen\": 3.0}, {\"site\": 773, \"mutant\": \"Q\", \"escape\": -0.014305047661502486, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.3042, \"times_seen\": 9.0}, {\"site\": 773, \"mutant\": \"R\", \"escape\": 0.007068473340394596, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.1008, \"times_seen\": 22.0}, {\"site\": 773, \"mutant\": \"T\", \"escape\": -0.006956206278571335, \"epitope\": \"epitope 1\", \"reference_site\": \"776\", \"functional effect\": 0.2622, \"times_seen\": 2.0}, {\"site\": 774, \"mutant\": \"D\", \"escape\": 0.014178976918057433, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -1.6319, \"times_seen\": 2.0}, {\"site\": 774, \"mutant\": \"H\", \"escape\": -0.012064651502714815, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -1.7783, \"times_seen\": 4.0}, {\"site\": 774, \"mutant\": \"K\", \"escape\": -0.0033029076405020645, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -2.3639, \"times_seen\": 1.0}, {\"site\": 774, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 774, \"mutant\": \"S\", \"escape\": 0.008706825831045558, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -1.8787, \"times_seen\": 5.0}, {\"site\": 774, \"mutant\": \"T\", \"escape\": -0.0009520259204442056, \"epitope\": \"epitope 1\", \"reference_site\": \"777\", \"functional effect\": -2.8274, \"times_seen\": 1.0}, {\"site\": 775, \"mutant\": \"A\", \"escape\": 0.03664749023880135, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -0.946, \"times_seen\": 13.0}, {\"site\": 775, \"mutant\": \"H\", \"escape\": 0.02389121016080795, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -2.3628, \"times_seen\": 2.0}, {\"site\": 775, \"mutant\": \"I\", \"escape\": -0.01323336806763132, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -0.4753, \"times_seen\": 40.0}, {\"site\": 775, \"mutant\": \"N\", \"escape\": 0.008692886419840484, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -1.1689, \"times_seen\": 12.0}, {\"site\": 775, \"mutant\": \"P\", \"escape\": 0.015038093778289924, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -2.5316, \"times_seen\": 2.0}, {\"site\": 775, \"mutant\": \"S\", \"escape\": 0.013144953787466468, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": -0.8224, \"times_seen\": 4.0}, {\"site\": 775, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"778\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 776, \"mutant\": \"*\", \"escape\": -0.015149668935000603, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -1.8032, \"times_seen\": 1.0}, {\"site\": 776, \"mutant\": \"E\", \"escape\": -1.3317378985857296, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": 0.3651, \"times_seen\": 14.0}, {\"site\": 776, \"mutant\": \"H\", \"escape\": -0.0010649233253811504, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -0.3563, \"times_seen\": 11.0}, {\"site\": 776, \"mutant\": \"K\", \"escape\": -0.0034568456735331464, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -0.2552, \"times_seen\": 27.0}, {\"site\": 776, \"mutant\": \"L\", \"escape\": -0.8433396562687939, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": 0.0398, \"times_seen\": 17.0}, {\"site\": 776, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -3.2663, \"times_seen\": null}, {\"site\": 776, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 776, \"mutant\": \"R\", \"escape\": 0.011800020394202335, \"epitope\": \"epitope 1\", \"reference_site\": \"779\", \"functional effect\": -0.0258, \"times_seen\": 15.0}, {\"site\": 777, \"mutant\": \"*\", \"escape\": -0.0022283854328563305, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -3.0345, \"times_seen\": 1.0}, {\"site\": 777, \"mutant\": \"A\", \"escape\": 9.111206546452163e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.0559, \"times_seen\": 3.0}, {\"site\": 777, \"mutant\": \"D\", \"escape\": -0.04960904787472224, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.2593, \"times_seen\": 26.0}, {\"site\": 777, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 777, \"mutant\": \"G\", \"escape\": -0.009466891259666719, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.1689, \"times_seen\": 14.0}, {\"site\": 777, \"mutant\": \"K\", \"escape\": 0.003633611602611424, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.0755, \"times_seen\": 21.0}, {\"site\": 777, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.576, \"times_seen\": null}, {\"site\": 777, \"mutant\": \"Q\", \"escape\": -0.07608889380574978, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": 0.0878, \"times_seen\": 10.0}, {\"site\": 777, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -1.6764, \"times_seen\": null}, {\"site\": 777, \"mutant\": \"S\", \"escape\": -0.013024472692235963, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.192, \"times_seen\": 10.0}, {\"site\": 777, \"mutant\": \"V\", \"escape\": -0.01081687859853319, \"epitope\": \"epitope 1\", \"reference_site\": \"780\", \"functional effect\": -0.4499, \"times_seen\": 6.0}, {\"site\": 778, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.0729, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.8674, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.9742, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"F\", \"escape\": -0.008039383376223954, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.1213, \"times_seen\": 1.0}, {\"site\": 778, \"mutant\": \"I\", \"escape\": 0.018295965102968603, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.5907, \"times_seen\": 1.0}, {\"site\": 778, \"mutant\": \"L\", \"escape\": -0.026680865260836312, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.2896, \"times_seen\": 9.0}, {\"site\": 778, \"mutant\": \"M\", \"escape\": -0.005819382387911574, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -2.2113, \"times_seen\": 2.0}, {\"site\": 778, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": -1.6866, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"781\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"C\", \"escape\": 0.014573455142233026, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.2009, \"times_seen\": 3.0}, {\"site\": 779, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.6266, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"L\", \"escape\": -0.0038141126016835373, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.3996, \"times_seen\": 2.0}, {\"site\": 779, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -2.92, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"Y\", \"escape\": -0.021206355853197804, \"epitope\": \"epitope 1\", \"reference_site\": \"782\", \"functional effect\": -0.2612, \"times_seen\": 8.0}, {\"site\": 780, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 780, \"mutant\": \"C\", \"escape\": -0.013030044131112714, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -1.3972, \"times_seen\": 3.0}, {\"site\": 780, \"mutant\": \"D\", \"escape\": 0.011580633426741684, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -1.0212, \"times_seen\": 2.0}, {\"site\": 780, \"mutant\": \"E\", \"escape\": -0.004051947667858006, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.1269, \"times_seen\": 1.0}, {\"site\": 780, \"mutant\": \"G\", \"escape\": -0.031650669274282076, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.1099, \"times_seen\": 14.0}, {\"site\": 780, \"mutant\": \"H\", \"escape\": -0.003826722378673646, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.5215, \"times_seen\": 1.0}, {\"site\": 780, \"mutant\": \"K\", \"escape\": -0.01833175906628701, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.5208, \"times_seen\": 6.0}, {\"site\": 780, \"mutant\": \"P\", \"escape\": -0.004073576139591893, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.8397, \"times_seen\": 1.0}, {\"site\": 780, \"mutant\": \"S\", \"escape\": -0.04302901360460991, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.7879, \"times_seen\": 22.0}, {\"site\": 780, \"mutant\": \"T\", \"escape\": -0.08422987139012497, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -1.0432, \"times_seen\": 39.0}, {\"site\": 780, \"mutant\": \"V\", \"escape\": -0.03941005962524964, \"epitope\": \"epitope 1\", \"reference_site\": \"783\", \"functional effect\": -0.59, \"times_seen\": 47.0}, {\"site\": 781, \"mutant\": \"*\", \"escape\": -0.013811502093327422, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -2.5266, \"times_seen\": 1.0}, {\"site\": 781, \"mutant\": \"H\", \"escape\": -1.8045183510644967, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.1042, \"times_seen\": 16.0}, {\"site\": 781, \"mutant\": \"K\", \"escape\": -0.04634358513212574, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -0.2481, \"times_seen\": 11.0}, {\"site\": 781, \"mutant\": \"L\", \"escape\": 0.2213206165731461, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.0136, \"times_seen\": 49.0}, {\"site\": 781, \"mutant\": \"P\", \"escape\": -0.023222389091537763, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -1.9129, \"times_seen\": 5.0}, {\"site\": 781, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 781, \"mutant\": \"R\", \"escape\": -0.06732346788750103, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": 0.0575, \"times_seen\": 60.0}, {\"site\": 781, \"mutant\": \"S\", \"escape\": -0.021823588501567733, \"epitope\": \"epitope 1\", \"reference_site\": \"784\", \"functional effect\": -0.377, \"times_seen\": 5.0}, {\"site\": 782, \"mutant\": \"A\", \"escape\": 0.018221232485159864, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.4484, \"times_seen\": 14.0}, {\"site\": 782, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 782, \"mutant\": \"F\", \"escape\": -0.0030890874591118105, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -1.1697, \"times_seen\": 1.0}, {\"site\": 782, \"mutant\": \"I\", \"escape\": -0.034505223391035345, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.1905, \"times_seen\": 16.0}, {\"site\": 782, \"mutant\": \"L\", \"escape\": -0.019445827075104276, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -1.029, \"times_seen\": 8.0}, {\"site\": 782, \"mutant\": \"M\", \"escape\": 0.008576345394138454, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -1.0268, \"times_seen\": 8.0}, {\"site\": 782, \"mutant\": \"Q\", \"escape\": 0.021489795838544733, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.767, \"times_seen\": 4.0}, {\"site\": 782, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": -0.3291, \"times_seen\": null}, {\"site\": 782, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"785\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 783, \"mutant\": \"E\", \"escape\": -0.008243277623578016, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": 0.0321, \"times_seen\": 3.0}, {\"site\": 783, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 783, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.2916, \"times_seen\": null}, {\"site\": 783, \"mutant\": \"N\", \"escape\": -0.020931045393361575, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.2182, \"times_seen\": 9.0}, {\"site\": 783, \"mutant\": \"Q\", \"escape\": -0.007001354818420385, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.0847, \"times_seen\": 2.0}, {\"site\": 783, \"mutant\": \"R\", \"escape\": 0.01574663525940826, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": 0.0834, \"times_seen\": 8.0}, {\"site\": 783, \"mutant\": \"T\", \"escape\": 0.007220028129686201, \"epitope\": \"epitope 1\", \"reference_site\": \"786\", \"functional effect\": -0.3067, \"times_seen\": 7.0}, {\"site\": 784, \"mutant\": \"*\", \"escape\": -0.019958913450395865, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -2.609, \"times_seen\": 4.0}, {\"site\": 784, \"mutant\": \"H\", \"escape\": -0.11076434879656258, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.1617, \"times_seen\": 51.0}, {\"site\": 784, \"mutant\": \"K\", \"escape\": 0.008888557169279835, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.249, \"times_seen\": 36.0}, {\"site\": 784, \"mutant\": \"L\", \"escape\": -0.006804787845346502, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.255, \"times_seen\": 16.0}, {\"site\": 784, \"mutant\": \"N\", \"escape\": 0.01324124836719122, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.6562, \"times_seen\": 8.0}, {\"site\": 784, \"mutant\": \"P\", \"escape\": -0.9176619545241992, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -0.731, \"times_seen\": 1.0}, {\"site\": 784, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 784, \"mutant\": \"R\", \"escape\": -0.018561943401178598, \"epitope\": \"epitope 1\", \"reference_site\": \"787\", \"functional effect\": -1.191, \"times_seen\": 9.0}, {\"site\": 785, \"mutant\": \"F\", \"escape\": 1.2648853049458701, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -2.6049, \"times_seen\": 2.0}, {\"site\": 785, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 785, \"mutant\": \"L\", \"escape\": 0.04823980589367255, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": 0.3002, \"times_seen\": 18.0}, {\"site\": 785, \"mutant\": \"M\", \"escape\": -0.03634203198965884, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -0.317, \"times_seen\": 13.0}, {\"site\": 785, \"mutant\": \"N\", \"escape\": -0.003040099382883919, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -0.9981, \"times_seen\": 2.0}, {\"site\": 785, \"mutant\": \"T\", \"escape\": 0.0029823409395473882, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -3.162, \"times_seen\": 1.0}, {\"site\": 785, \"mutant\": \"V\", \"escape\": 0.028502536264020082, \"epitope\": \"epitope 1\", \"reference_site\": \"788\", \"functional effect\": -1.9642, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"*\", \"escape\": -0.006230840868929303, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.8941, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"C\", \"escape\": -0.005243749657737673, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.9036, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"H\", \"escape\": -0.030193841037497563, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": 0.0132, \"times_seen\": 13.0}, {\"site\": 786, \"mutant\": \"N\", \"escape\": 0.021797426712160298, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.782, \"times_seen\": 3.0}, {\"site\": 786, \"mutant\": \"Q\", \"escape\": 0.019049253125519652, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"T\", \"escape\": -0.004372337538491242, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": -2.8037, \"times_seen\": 3.0}, {\"site\": 786, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"789\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"E\", \"escape\": 0.02612978870813301, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -2.1323, \"times_seen\": 13.0}, {\"site\": 787, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -2.6097, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"I\", \"escape\": 0.0017574226066614223, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -0.6658, \"times_seen\": 2.0}, {\"site\": 787, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"M\", \"escape\": 0.0012629857537921891, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -0.5911, \"times_seen\": 3.0}, {\"site\": 787, \"mutant\": \"N\", \"escape\": -0.0183561527594437, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -1.1482, \"times_seen\": 18.0}, {\"site\": 787, \"mutant\": \"Q\", \"escape\": 0.0317992475163589, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": -0.3125, \"times_seen\": 14.0}, {\"site\": 787, \"mutant\": \"R\", \"escape\": 0.008826498311661529, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": 0.187, \"times_seen\": 16.0}, {\"site\": 787, \"mutant\": \"T\", \"escape\": -0.03908597499724799, \"epitope\": \"epitope 1\", \"reference_site\": \"790\", \"functional effect\": 0.0374, \"times_seen\": 8.0}, {\"site\": 788, \"mutant\": \"A\", \"escape\": -0.018502170324519077, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": 0.064, \"times_seen\": 7.0}, {\"site\": 788, \"mutant\": \"H\", \"escape\": -0.010409264661885954, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.09, \"times_seen\": 6.0}, {\"site\": 788, \"mutant\": \"I\", \"escape\": -0.007986060935629244, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.0181, \"times_seen\": 25.0}, {\"site\": 788, \"mutant\": \"K\", \"escape\": -0.021646118888207222, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.5386, \"times_seen\": 23.0}, {\"site\": 788, \"mutant\": \"N\", \"escape\": -0.0104100864200283, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.9177, \"times_seen\": 3.0}, {\"site\": 788, \"mutant\": \"P\", \"escape\": -0.008460850998535439, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": 0.036, \"times_seen\": 5.0}, {\"site\": 788, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.6799, \"times_seen\": null}, {\"site\": 788, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": -0.0459, \"times_seen\": null}, {\"site\": 788, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"791\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": 0.6623, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"H\", \"escape\": -0.002349984801619228, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.6043, \"times_seen\": 7.0}, {\"site\": 789, \"mutant\": \"L\", \"escape\": 0.01713903127483137, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.4385, \"times_seen\": 36.0}, {\"site\": 789, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.9385, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"Q\", \"escape\": -0.02027006454443285, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.2454, \"times_seen\": 4.0}, {\"site\": 789, \"mutant\": \"R\", \"escape\": 0.19579696684387363, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.6375, \"times_seen\": 4.0}, {\"site\": 789, \"mutant\": \"S\", \"escape\": -0.010511390383075265, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.269, \"times_seen\": 11.0}, {\"site\": 789, \"mutant\": \"T\", \"escape\": -0.028647568184266285, \"epitope\": \"epitope 1\", \"reference_site\": \"792\", \"functional effect\": -0.2892, \"times_seen\": 20.0}, {\"site\": 790, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 790, \"mutant\": \"L\", \"escape\": -0.055487780128913054, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": -0.053, \"times_seen\": 26.0}, {\"site\": 790, \"mutant\": \"N\", \"escape\": -0.012685390469926089, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.3933, \"times_seen\": 16.0}, {\"site\": 790, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 790, \"mutant\": \"Q\", \"escape\": -0.0009156358261885675, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.2878, \"times_seen\": 9.0}, {\"site\": 790, \"mutant\": \"R\", \"escape\": 0.005519162052649468, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.3498, \"times_seen\": 1.0}, {\"site\": 790, \"mutant\": \"S\", \"escape\": -0.30291017246037677, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.3254, \"times_seen\": 26.0}, {\"site\": 790, \"mutant\": \"T\", \"escape\": -0.01750295269878425, \"epitope\": \"epitope 1\", \"reference_site\": \"793\", \"functional effect\": 0.1526, \"times_seen\": 8.0}, {\"site\": 791, \"mutant\": \"F\", \"escape\": 0.009945688553515302, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.31, \"times_seen\": 12.0}, {\"site\": 791, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 791, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 791, \"mutant\": \"L\", \"escape\": -0.005590671302516151, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": -0.5619, \"times_seen\": 2.0}, {\"site\": 791, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 791, \"mutant\": \"N\", \"escape\": 0.014798537566702399, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.2922, \"times_seen\": 3.0}, {\"site\": 791, \"mutant\": \"T\", \"escape\": 0.010956100717975967, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.3158, \"times_seen\": 9.0}, {\"site\": 791, \"mutant\": \"V\", \"escape\": 0.004042430682419646, \"epitope\": \"epitope 1\", \"reference_site\": \"794\", \"functional effect\": 0.0945, \"times_seen\": 4.0}, {\"site\": 792, \"mutant\": \"E\", \"escape\": -0.006496688300427521, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": -0.9126, \"times_seen\": 14.0}, {\"site\": 792, \"mutant\": \"I\", \"escape\": 0.002145702209030231, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": -0.2489, \"times_seen\": 2.0}, {\"site\": 792, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 792, \"mutant\": \"M\", \"escape\": -0.0016706791568223498, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 792, \"mutant\": \"N\", \"escape\": 0.018007438329622344, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.1416, \"times_seen\": 34.0}, {\"site\": 792, \"mutant\": \"R\", \"escape\": 0.002377827656115914, \"epitope\": \"epitope 1\", \"reference_site\": \"795\", \"functional effect\": 0.4099, \"times_seen\": 23.0}, {\"site\": 793, \"mutant\": \"*\", \"escape\": -0.007057463174004238, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -3.0468, \"times_seen\": 2.0}, {\"site\": 793, \"mutant\": \"A\", \"escape\": -0.04927029854462912, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.2063, \"times_seen\": 20.0}, {\"site\": 793, \"mutant\": \"C\", \"escape\": 0.034585895304770124, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.1096, \"times_seen\": 18.0}, {\"site\": 793, \"mutant\": \"D\", \"escape\": -4.497082775191083, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 793, \"mutant\": \"E\", \"escape\": -0.021736067202883323, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.3958, \"times_seen\": 14.0}, {\"site\": 793, \"mutant\": \"F\", \"escape\": -0.016226519071114588, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -1.3189, \"times_seen\": 15.0}, {\"site\": 793, \"mutant\": \"G\", \"escape\": -0.12239991365275164, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.1069, \"times_seen\": 27.0}, {\"site\": 793, \"mutant\": \"H\", \"escape\": -0.08515568652609494, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.3463, \"times_seen\": 26.0}, {\"site\": 793, \"mutant\": \"I\", \"escape\": -0.032125110804564455, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.1034, \"times_seen\": 16.0}, {\"site\": 793, \"mutant\": \"K\", \"escape\": -0.012376288793658494, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.3197, \"times_seen\": 3.0}, {\"site\": 793, \"mutant\": \"L\", \"escape\": -0.05253775286813706, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.3055, \"times_seen\": 21.0}, {\"site\": 793, \"mutant\": \"M\", \"escape\": 0.0014911093339178036, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.0388, \"times_seen\": 3.0}, {\"site\": 793, \"mutant\": \"N\", \"escape\": -0.08597785674634915, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.4141, \"times_seen\": 44.0}, {\"site\": 793, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -2.8316, \"times_seen\": null}, {\"site\": 793, \"mutant\": \"Q\", \"escape\": -0.009579347259148866, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.2016, \"times_seen\": 4.0}, {\"site\": 793, \"mutant\": \"R\", \"escape\": -0.0006084273027846575, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -1.0075, \"times_seen\": 13.0}, {\"site\": 793, \"mutant\": \"S\", \"escape\": -1.2277139810150022, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.4444, \"times_seen\": 52.0}, {\"site\": 793, \"mutant\": \"T\", \"escape\": -0.0624452140951603, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.0623, \"times_seen\": 20.0}, {\"site\": 793, \"mutant\": \"V\", \"escape\": 0.002028843431528255, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -0.0814, \"times_seen\": 26.0}, {\"site\": 793, \"mutant\": \"W\", \"escape\": -0.0016898385534233405, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": -1.3168, \"times_seen\": 7.0}, {\"site\": 793, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"796\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 794, \"mutant\": \"C\", \"escape\": -0.010500076265359174, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -1.1026, \"times_seen\": 6.0}, {\"site\": 794, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 794, \"mutant\": \"I\", \"escape\": -0.003691835571959311, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -0.7217, \"times_seen\": 2.0}, {\"site\": 794, \"mutant\": \"L\", \"escape\": -0.019530272294988067, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 794, \"mutant\": \"S\", \"escape\": 0.1030993860958927, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -1.0526, \"times_seen\": 4.0}, {\"site\": 794, \"mutant\": \"V\", \"escape\": 0.040326061291883035, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -1.2891, \"times_seen\": 2.0}, {\"site\": 794, \"mutant\": \"Y\", \"escape\": -0.004625156322985781, \"epitope\": \"epitope 1\", \"reference_site\": \"797\", \"functional effect\": -0.3219, \"times_seen\": 2.0}, {\"site\": 795, \"mutant\": \"A\", \"escape\": -0.0005586466304156926, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": 0.0924, \"times_seen\": 3.0}, {\"site\": 795, \"mutant\": \"C\", \"escape\": -0.010915251399969078, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -1.6839, \"times_seen\": 2.0}, {\"site\": 795, \"mutant\": \"D\", \"escape\": -0.010078778775022893, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 795, \"mutant\": \"E\", \"escape\": -0.0032698739962554835, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 795, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 795, \"mutant\": \"R\", \"escape\": -0.011721996559555496, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -0.3295, \"times_seen\": 4.0}, {\"site\": 795, \"mutant\": \"S\", \"escape\": 0.047017308288679, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -0.3617, \"times_seen\": 10.0}, {\"site\": 795, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -2.8864, \"times_seen\": null}, {\"site\": 795, \"mutant\": \"W\", \"escape\": -0.018611218972420913, \"epitope\": \"epitope 1\", \"reference_site\": \"798\", \"functional effect\": -0.7709, \"times_seen\": 3.0}, {\"site\": 796, \"mutant\": \"C\", \"escape\": -0.0206256940452541, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -2.0614, \"times_seen\": 6.0}, {\"site\": 796, \"mutant\": \"D\", \"escape\": -0.00587376402045374, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -2.0504, \"times_seen\": 9.0}, {\"site\": 796, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 796, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 796, \"mutant\": \"S\", \"escape\": -0.004471409088293432, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -2.6231, \"times_seen\": 2.0}, {\"site\": 796, \"mutant\": \"V\", \"escape\": -0.005829952172719762, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -3.0068, \"times_seen\": 2.0}, {\"site\": 796, \"mutant\": \"W\", \"escape\": -0.0022345829112447105, \"epitope\": \"epitope 1\", \"reference_site\": \"799\", \"functional effect\": -1.0263, \"times_seen\": 1.0}, {\"site\": 797, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 797, \"mutant\": \"I\", \"escape\": 0.033053559915266685, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.5187, \"times_seen\": 2.0}, {\"site\": 797, \"mutant\": \"L\", \"escape\": 0.007697378851841121, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.5735, \"times_seen\": 4.0}, {\"site\": 797, \"mutant\": \"S\", \"escape\": -0.0020988179432084074, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.3392, \"times_seen\": 1.0}, {\"site\": 797, \"mutant\": \"V\", \"escape\": -0.0027436501125332247, \"epitope\": \"epitope 1\", \"reference_site\": \"800\", \"functional effect\": -2.9684, \"times_seen\": 1.0}, {\"site\": 798, \"mutant\": \"D\", \"escape\": 0.02049082032868008, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": 0.1322, \"times_seen\": 18.0}, {\"site\": 798, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 798, \"mutant\": \"I\", \"escape\": -0.008583923159250497, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -2.2033, \"times_seen\": 1.0}, {\"site\": 798, \"mutant\": \"K\", \"escape\": -0.006422245415111377, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 798, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 798, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"801\", \"functional effect\": -3.0358, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -2.0436, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -3.1372, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"L\", \"escape\": -0.009944638532123958, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -2.1336, \"times_seen\": 3.0}, {\"site\": 799, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -1.5288, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"802\", \"functional effect\": -0.9458, \"times_seen\": null}, {\"site\": 800, \"mutant\": \"A\", \"escape\": 0.0012358801130460337, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.9067, \"times_seen\": 2.0}, {\"site\": 800, \"mutant\": \"F\", \"escape\": 0.010199127186269643, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -2.2039, \"times_seen\": 4.0}, {\"site\": 800, \"mutant\": \"G\", \"escape\": 0.010938539487318117, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.764, \"times_seen\": 3.0}, {\"site\": 800, \"mutant\": \"H\", \"escape\": 0.01092810664600463, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.5422, \"times_seen\": 7.0}, {\"site\": 800, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -2.8923, \"times_seen\": null}, {\"site\": 800, \"mutant\": \"L\", \"escape\": 0.0022666946254947186, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -1.4122, \"times_seen\": 15.0}, {\"site\": 800, \"mutant\": \"N\", \"escape\": -0.02337316883882844, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.3901, \"times_seen\": 8.0}, {\"site\": 800, \"mutant\": \"R\", \"escape\": -0.009600965717669453, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.2646, \"times_seen\": 3.0}, {\"site\": 800, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 800, \"mutant\": \"T\", \"escape\": -0.007542578844476658, \"epitope\": \"epitope 1\", \"reference_site\": \"803\", \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 801, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -1.5857, \"times_seen\": null}, {\"site\": 801, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 801, \"mutant\": \"H\", \"escape\": 0.020428918441857652, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -0.4395, \"times_seen\": 11.0}, {\"site\": 801, \"mutant\": \"K\", \"escape\": -0.0037326938196682083, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -0.1603, \"times_seen\": 17.0}, {\"site\": 801, \"mutant\": \"L\", \"escape\": -0.006373759088031799, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 801, \"mutant\": \"P\", \"escape\": 0.006057615440955612, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.3861, \"times_seen\": 5.0}, {\"site\": 801, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 801, \"mutant\": \"R\", \"escape\": -0.004101778848201438, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": -0.0333, \"times_seen\": 7.0}, {\"site\": 801, \"mutant\": \"T\", \"escape\": 0.001547914957979836, \"epitope\": \"epitope 1\", \"reference_site\": \"804\", \"functional effect\": 0.1817, \"times_seen\": 3.0}, {\"site\": 802, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 802, \"mutant\": \"L\", \"escape\": -0.006243623828595215, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": 0.0932, \"times_seen\": 4.0}, {\"site\": 802, \"mutant\": \"M\", \"escape\": -0.00038757712337255355, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -0.5141, \"times_seen\": 19.0}, {\"site\": 802, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -3.1385, \"times_seen\": null}, {\"site\": 802, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -3.15, \"times_seen\": null}, {\"site\": 802, \"mutant\": \"V\", \"escape\": 0.0006666888824621928, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -0.3151, \"times_seen\": 4.0}, {\"site\": 802, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"805\", \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"F\", \"escape\": -0.006733086440215248, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -0.2975, \"times_seen\": 2.0}, {\"site\": 803, \"mutant\": \"I\", \"escape\": -0.006736896887281202, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -1.7201, \"times_seen\": 2.0}, {\"site\": 803, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"M\", \"escape\": -0.0027573207883407396, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": 0.0086, \"times_seen\": 3.0}, {\"site\": 803, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -2.1869, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -2.8206, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -2.3767, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"V\", \"escape\": 0.005721583080616421, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -1.5347, \"times_seen\": 5.0}, {\"site\": 803, \"mutant\": \"Y\", \"escape\": 0.009792287707040779, \"epitope\": \"epitope 1\", \"reference_site\": \"806\", \"functional effect\": -0.0491, \"times_seen\": 3.0}, {\"site\": 804, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 804, \"mutant\": \"H\", \"escape\": -0.04862440399786981, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.766, \"times_seen\": 11.0}, {\"site\": 804, \"mutant\": \"L\", \"escape\": -0.03788514646220059, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -1.3191, \"times_seen\": 21.0}, {\"site\": 804, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 804, \"mutant\": \"Q\", \"escape\": 0.001604222813294066, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.3064, \"times_seen\": 9.0}, {\"site\": 804, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -1.7397, \"times_seen\": null}, {\"site\": 804, \"mutant\": \"S\", \"escape\": -0.8794255306535864, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.0774, \"times_seen\": 61.0}, {\"site\": 804, \"mutant\": \"T\", \"escape\": -0.009331141713991988, \"epitope\": \"epitope 1\", \"reference_site\": \"807\", \"functional effect\": -0.4701, \"times_seen\": 3.0}, {\"site\": 805, \"mutant\": \"A\", \"escape\": 0.009139150892982874, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.2046, \"times_seen\": 5.0}, {\"site\": 805, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 805, \"mutant\": \"E\", \"escape\": -0.006277926872806379, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.2332, \"times_seen\": 11.0}, {\"site\": 805, \"mutant\": \"G\", \"escape\": -0.06256755562750543, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.829, \"times_seen\": 17.0}, {\"site\": 805, \"mutant\": \"H\", \"escape\": -0.001874114667160307, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.8279, \"times_seen\": 30.0}, {\"site\": 805, \"mutant\": \"I\", \"escape\": 0.032763508782089626, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.4157, \"times_seen\": 4.0}, {\"site\": 805, \"mutant\": \"N\", \"escape\": -0.047085156520502186, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.4902, \"times_seen\": 37.0}, {\"site\": 805, \"mutant\": \"R\", \"escape\": 0.0077008907572325425, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -1.0512, \"times_seen\": 3.0}, {\"site\": 805, \"mutant\": \"S\", \"escape\": -0.008377200698598904, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.6862, \"times_seen\": 3.0}, {\"site\": 805, \"mutant\": \"V\", \"escape\": -0.01012369234064492, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -0.0955, \"times_seen\": 5.0}, {\"site\": 805, \"mutant\": \"Y\", \"escape\": -0.008070868941935474, \"epitope\": \"epitope 1\", \"reference_site\": \"808\", \"functional effect\": -2.7158, \"times_seen\": 3.0}, {\"site\": 806, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -1.2617, \"times_seen\": null}, {\"site\": 806, \"mutant\": \"H\", \"escape\": 0.020392099473990795, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.4214, \"times_seen\": 3.0}, {\"site\": 806, \"mutant\": \"L\", \"escape\": 0.004730202369104073, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.1099, \"times_seen\": 24.0}, {\"site\": 806, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 806, \"mutant\": \"Q\", \"escape\": -0.030996501293601993, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.1306, \"times_seen\": 14.0}, {\"site\": 806, \"mutant\": \"R\", \"escape\": 0.015116803411536272, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.3906, \"times_seen\": 2.0}, {\"site\": 806, \"mutant\": \"S\", \"escape\": -0.003139076163706321, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.0518, \"times_seen\": 11.0}, {\"site\": 806, \"mutant\": \"T\", \"escape\": -0.0767627466342188, \"epitope\": \"epitope 1\", \"reference_site\": \"809\", \"functional effect\": -0.1149, \"times_seen\": 28.0}, {\"site\": 807, \"mutant\": \"A\", \"escape\": 0.029622369967572604, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.0312, \"times_seen\": 19.0}, {\"site\": 807, \"mutant\": \"G\", \"escape\": -0.02571433938132676, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.0043, \"times_seen\": 8.0}, {\"site\": 807, \"mutant\": \"I\", \"escape\": 0.06368801236059078, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.3514, \"times_seen\": 25.0}, {\"site\": 807, \"mutant\": \"L\", \"escape\": -0.02919049709080979, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.1477, \"times_seen\": 15.0}, {\"site\": 807, \"mutant\": \"N\", \"escape\": -0.03147959623039431, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.4062, \"times_seen\": 25.0}, {\"site\": 807, \"mutant\": \"Q\", \"escape\": -0.6518987106585709, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": 0.1263, \"times_seen\": 17.0}, {\"site\": 807, \"mutant\": \"R\", \"escape\": 0.8885322584845802, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": -0.1915, \"times_seen\": 12.0}, {\"site\": 807, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 807, \"mutant\": \"T\", \"escape\": 0.013068955261642184, \"epitope\": \"epitope 1\", \"reference_site\": \"810\", \"functional effect\": 0.0096, \"times_seen\": 15.0}, {\"site\": 808, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -3.1474, \"times_seen\": null}, {\"site\": 808, \"mutant\": \"E\", \"escape\": -0.014271129905264064, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -1.267, \"times_seen\": 5.0}, {\"site\": 808, \"mutant\": \"I\", \"escape\": 0.002948295528787689, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.1502, \"times_seen\": 4.0}, {\"site\": 808, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 808, \"mutant\": \"N\", \"escape\": 0.06366381993874529, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.5554, \"times_seen\": 14.0}, {\"site\": 808, \"mutant\": \"Q\", \"escape\": 0.015104813650614524, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.1551, \"times_seen\": 11.0}, {\"site\": 808, \"mutant\": \"R\", \"escape\": -0.024092627074474172, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.1412, \"times_seen\": 19.0}, {\"site\": 808, \"mutant\": \"T\", \"escape\": -0.024859192742971943, \"epitope\": \"epitope 1\", \"reference_site\": \"811\", \"functional effect\": -0.082, \"times_seen\": 6.0}, {\"site\": 809, \"mutant\": \"A\", \"escape\": 0.018221174284543087, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.1726, \"times_seen\": 8.0}, {\"site\": 809, \"mutant\": \"L\", \"escape\": -0.6961484462797096, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.2061, \"times_seen\": 26.0}, {\"site\": 809, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 809, \"mutant\": \"Q\", \"escape\": 0.002322221610145294, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.082, \"times_seen\": 10.0}, {\"site\": 809, \"mutant\": \"R\", \"escape\": -0.016957979925751227, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.2985, \"times_seen\": 10.0}, {\"site\": 809, \"mutant\": \"S\", \"escape\": -0.007766769346379185, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": -0.2188, \"times_seen\": 18.0}, {\"site\": 809, \"mutant\": \"T\", \"escape\": 0.08052381860211404, \"epitope\": \"epitope 1\", \"reference_site\": \"812\", \"functional effect\": 0.0767, \"times_seen\": 35.0}, {\"site\": 810, \"mutant\": \"*\", \"escape\": -0.0028876139785325534, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -2.1747, \"times_seen\": 1.0}, {\"site\": 810, \"mutant\": \"A\", \"escape\": 0.03502056999511348, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7802, \"times_seen\": 23.0}, {\"site\": 810, \"mutant\": \"C\", \"escape\": -0.0069348869738517045, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -1.1521, \"times_seen\": 26.0}, {\"site\": 810, \"mutant\": \"D\", \"escape\": 0.0026632223371901424, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": 0.0399, \"times_seen\": 11.0}, {\"site\": 810, \"mutant\": \"E\", \"escape\": 0.5784282377889961, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.3491, \"times_seen\": 9.0}, {\"site\": 810, \"mutant\": \"F\", \"escape\": 0.016129286526261066, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.5532, \"times_seen\": 7.0}, {\"site\": 810, \"mutant\": \"G\", \"escape\": -0.0504344502961911, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": 0.2633, \"times_seen\": 110.0}, {\"site\": 810, \"mutant\": \"H\", \"escape\": -0.012466316699890224, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7006, \"times_seen\": 8.0}, {\"site\": 810, \"mutant\": \"I\", \"escape\": -0.024491746067271423, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.4102, \"times_seen\": 41.0}, {\"site\": 810, \"mutant\": \"K\", \"escape\": -0.05961283286526268, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7068, \"times_seen\": 20.0}, {\"site\": 810, \"mutant\": \"L\", \"escape\": -0.46209224413487193, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -1.0156, \"times_seen\": 30.0}, {\"site\": 810, \"mutant\": \"M\", \"escape\": -0.005539977132333637, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.6356, \"times_seen\": 15.0}, {\"site\": 810, \"mutant\": \"N\", \"escape\": 0.20117532411233902, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.5575, \"times_seen\": 54.0}, {\"site\": 810, \"mutant\": \"P\", \"escape\": -0.019220271069830548, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -2.0002, \"times_seen\": 6.0}, {\"site\": 810, \"mutant\": \"Q\", \"escape\": 0.0015131416175986658, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.3979, \"times_seen\": 7.0}, {\"site\": 810, \"mutant\": \"R\", \"escape\": -0.05557512054707627, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7631, \"times_seen\": 62.0}, {\"site\": 810, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 810, \"mutant\": \"T\", \"escape\": -0.05693887466939619, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.017, \"times_seen\": 27.0}, {\"site\": 810, \"mutant\": \"V\", \"escape\": -0.06043540529945231, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.6807, \"times_seen\": 12.0}, {\"site\": 810, \"mutant\": \"W\", \"escape\": 0.01289073282794632, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -0.7585, \"times_seen\": 13.0}, {\"site\": 810, \"mutant\": \"Y\", \"escape\": 0.04072452361700291, \"epitope\": \"epitope 1\", \"reference_site\": \"813\", \"functional effect\": -1.1562, \"times_seen\": 18.0}, {\"site\": 811, \"mutant\": \"E\", \"escape\": -0.001098177483085985, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.1731, \"times_seen\": 13.0}, {\"site\": 811, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 811, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 811, \"mutant\": \"M\", \"escape\": 0.018434296023465184, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.1107, \"times_seen\": 5.0}, {\"site\": 811, \"mutant\": \"N\", \"escape\": -0.011726264538847609, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.7483, \"times_seen\": 11.0}, {\"site\": 811, \"mutant\": \"Q\", \"escape\": -0.0011410326754008617, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": 0.3921, \"times_seen\": 19.0}, {\"site\": 811, \"mutant\": \"R\", \"escape\": -0.00043530479884369174, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.3986, \"times_seen\": 48.0}, {\"site\": 811, \"mutant\": \"T\", \"escape\": -0.018601368435337995, \"epitope\": \"epitope 1\", \"reference_site\": \"814\", \"functional effect\": -0.3278, \"times_seen\": 7.0}, {\"site\": 812, \"mutant\": \"G\", \"escape\": -0.007222788753159262, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -2.9512, \"times_seen\": 2.0}, {\"site\": 812, \"mutant\": \"K\", \"escape\": 0.008958187833110419, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": 0.2028, \"times_seen\": 19.0}, {\"site\": 812, \"mutant\": \"M\", \"escape\": -0.02366798582485017, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -0.5388, \"times_seen\": 8.0}, {\"site\": 812, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 812, \"mutant\": \"S\", \"escape\": -0.007819859916356966, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -2.9839, \"times_seen\": 2.0}, {\"site\": 812, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"815\", \"functional effect\": -3.0625, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.4196, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.9671, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.4335, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"P\", \"escape\": -0.003320216226017493, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -3.0622, \"times_seen\": 1.0}, {\"site\": 813, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"T\", \"escape\": -0.0034609148154640247, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.7514, \"times_seen\": 1.0}, {\"site\": 813, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"816\", \"functional effect\": -2.9258, \"times_seen\": null}, {\"site\": 814, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": -2.0337, \"times_seen\": null}, {\"site\": 814, \"mutant\": \"C\", \"escape\": -0.0037442110543976256, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 814, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 814, \"mutant\": \"I\", \"escape\": 0.008513156419062163, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"mutant\": \"L\", \"escape\": -0.01148757054594968, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.0834, \"times_seen\": 25.0}, {\"site\": 814, \"mutant\": \"S\", \"escape\": -0.01627928221818006, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.2055, \"times_seen\": 6.0}, {\"site\": 814, \"mutant\": \"V\", \"escape\": -0.01455447648267449, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"mutant\": \"Y\", \"escape\": -0.01032831306659993, \"epitope\": \"epitope 1\", \"reference_site\": \"817\", \"functional effect\": -0.2441, \"times_seen\": 3.0}, {\"site\": 815, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.803, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.02, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -0.2899, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -2.8965, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"T\", \"escape\": 8.804452214837375e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -2.8434, \"times_seen\": 1.0}, {\"site\": 815, \"mutant\": \"V\", \"escape\": -0.0028086444591653675, \"epitope\": \"epitope 1\", \"reference_site\": \"818\", \"functional effect\": -1.0312, \"times_seen\": 1.0}, {\"site\": 816, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -3.1856, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.2359, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"D\", \"escape\": -0.008796917110199875, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -1.8798, \"times_seen\": 2.0}, {\"site\": 816, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"G\", \"escape\": -0.14741661321128854, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.0993, \"times_seen\": 3.0}, {\"site\": 816, \"mutant\": \"K\", \"escape\": 0.020052877468418148, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.1785, \"times_seen\": 1.0}, {\"site\": 816, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.6892, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"819\", \"functional effect\": -2.9667, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"A\", \"escape\": 0.020812939634792534, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.2577, \"times_seen\": 2.0}, {\"site\": 817, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"E\", \"escape\": 0.012445537908113985, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -0.1336, \"times_seen\": 4.0}, {\"site\": 817, \"mutant\": \"G\", \"escape\": -0.001241133116798057, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -1.7228, \"times_seen\": 2.0}, {\"site\": 817, \"mutant\": \"H\", \"escape\": -0.004566590182908952, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -0.7693, \"times_seen\": 1.0}, {\"site\": 817, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.0701, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"N\", \"escape\": -0.21223681312470033, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -0.8352, \"times_seen\": 37.0}, {\"site\": 817, \"mutant\": \"V\", \"escape\": -0.010778350152094713, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.0232, \"times_seen\": 2.0}, {\"site\": 817, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"820\", \"functional effect\": -2.7805, \"times_seen\": null}, {\"site\": 818, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 818, \"mutant\": \"I\", \"escape\": 0.0014612933174910708, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": 0.1336, \"times_seen\": 11.0}, {\"site\": 818, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 818, \"mutant\": \"M\", \"escape\": -0.022277767363953493, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -0.5161, \"times_seen\": 9.0}, {\"site\": 818, \"mutant\": \"P\", \"escape\": -0.010506372674611396, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -1.8992, \"times_seen\": 4.0}, {\"site\": 818, \"mutant\": \"Q\", \"escape\": -0.005414560349786148, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -1.7887, \"times_seen\": 2.0}, {\"site\": 818, \"mutant\": \"R\", \"escape\": -0.001306206373580624, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -2.6414, \"times_seen\": 1.0}, {\"site\": 818, \"mutant\": \"V\", \"escape\": -0.007697962593737942, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -0.3849, \"times_seen\": 17.0}, {\"site\": 818, \"mutant\": \"Y\", \"escape\": -0.0059929003514591515, \"epitope\": \"epitope 1\", \"reference_site\": \"821\", \"functional effect\": -2.4362, \"times_seen\": 2.0}, {\"site\": 819, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"F\", \"escape\": 0.5535983997079085, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -0.815, \"times_seen\": 4.0}, {\"site\": 819, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.0771, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"M\", \"escape\": -0.014918745900969083, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -0.6487, \"times_seen\": 6.0}, {\"site\": 819, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.2833, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.8673, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"R\", \"escape\": 0.005566950171968447, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -2.6705, \"times_seen\": 1.0}, {\"site\": 819, \"mutant\": \"V\", \"escape\": 0.0036504945522194744, \"epitope\": \"epitope 1\", \"reference_site\": \"822\", \"functional effect\": -1.7285, \"times_seen\": 1.0}, {\"site\": 820, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -3.146, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -3.0631, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"L\", \"escape\": -0.01838936511623998, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -2.1796, \"times_seen\": 4.0}, {\"site\": 820, \"mutant\": \"S\", \"escape\": -0.01735189883612256, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -2.2322, \"times_seen\": 3.0}, {\"site\": 820, \"mutant\": \"V\", \"escape\": -0.011092393533795887, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": -2.1635, \"times_seen\": 1.0}, {\"site\": 820, \"mutant\": \"Y\", \"escape\": -0.6634712380519485, \"epitope\": \"epitope 1\", \"reference_site\": \"823\", \"functional effect\": 0.0194, \"times_seen\": 28.0}, {\"site\": 821, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 821, \"mutant\": \"D\", \"escape\": -0.006881406850267632, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.273, \"times_seen\": 14.0}, {\"site\": 821, \"mutant\": \"H\", \"escape\": -0.009383228462651494, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -1.0801, \"times_seen\": 3.0}, {\"site\": 821, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 821, \"mutant\": \"K\", \"escape\": -0.008388931760298706, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -0.5735, \"times_seen\": 7.0}, {\"site\": 821, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 821, \"mutant\": \"Q\", \"escape\": -0.002624633926550695, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.1575, \"times_seen\": 1.0}, {\"site\": 821, \"mutant\": \"S\", \"escape\": 0.002094413949701497, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.2537, \"times_seen\": 7.0}, {\"site\": 821, \"mutant\": \"T\", \"escape\": -0.010974997374329314, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 821, \"mutant\": \"Y\", \"escape\": 0.08746897353708681, \"epitope\": \"epitope 1\", \"reference_site\": \"824\", \"functional effect\": -1.385, \"times_seen\": 12.0}, {\"site\": 822, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -3.0041, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"E\", \"escape\": 0.015368730867334014, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -1.0352, \"times_seen\": 13.0}, {\"site\": 822, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"M\", \"escape\": -0.0038243916578195743, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -1.034, \"times_seen\": 1.0}, {\"site\": 822, \"mutant\": \"N\", \"escape\": -0.004032961647349961, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -2.8967, \"times_seen\": 1.0}, {\"site\": 822, \"mutant\": \"Q\", \"escape\": -0.009540254252643, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.0144, \"times_seen\": 4.0}, {\"site\": 822, \"mutant\": \"R\", \"escape\": -0.025195114905159643, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.3462, \"times_seen\": 15.0}, {\"site\": 822, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"825\", \"functional effect\": -0.9509, \"times_seen\": null}, {\"site\": 823, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 823, \"mutant\": \"A\", \"escape\": 0.019040288756253163, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -1.3643, \"times_seen\": 4.0}, {\"site\": 823, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -1.6687, \"times_seen\": null}, {\"site\": 823, \"mutant\": \"G\", \"escape\": 0.03369216843301861, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -2.364, \"times_seen\": 4.0}, {\"site\": 823, \"mutant\": \"I\", \"escape\": 0.012465876304663203, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -0.3888, \"times_seen\": 6.0}, {\"site\": 823, \"mutant\": \"L\", \"escape\": -0.047810045594826, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -0.625, \"times_seen\": 45.0}, {\"site\": 823, \"mutant\": \"M\", \"escape\": 0.0061172083539680734, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -0.2696, \"times_seen\": 16.0}, {\"site\": 823, \"mutant\": \"S\", \"escape\": -0.008067254756412014, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": -2.0156, \"times_seen\": 3.0}, {\"site\": 823, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"826\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"A\", \"escape\": -0.05363551174000319, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.6488, \"times_seen\": 46.0}, {\"site\": 824, \"mutant\": \"H\", \"escape\": -0.03370157849355212, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.916, \"times_seen\": 8.0}, {\"site\": 824, \"mutant\": \"I\", \"escape\": -0.02766355651255877, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.2732, \"times_seen\": 48.0}, {\"site\": 824, \"mutant\": \"L\", \"escape\": -0.011459375103196051, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -1.6449, \"times_seen\": 4.0}, {\"site\": 824, \"mutant\": \"N\", \"escape\": -0.004231846149825297, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.3136, \"times_seen\": 3.0}, {\"site\": 824, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -1.2831, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"S\", \"escape\": -0.001483627097855195, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -0.2808, \"times_seen\": 17.0}, {\"site\": 824, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"Y\", \"escape\": -0.0065111934901407155, \"epitope\": \"epitope 1\", \"reference_site\": \"827\", \"functional effect\": -2.4549, \"times_seen\": 2.0}, {\"site\": 825, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 825, \"mutant\": \"F\", \"escape\": -0.045284250679268806, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.2707, \"times_seen\": 22.0}, {\"site\": 825, \"mutant\": \"I\", \"escape\": -0.713100021806795, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.0602, \"times_seen\": 15.0}, {\"site\": 825, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 825, \"mutant\": \"M\", \"escape\": -0.017799957336815764, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": 0.1565, \"times_seen\": 8.0}, {\"site\": 825, \"mutant\": \"P\", \"escape\": -0.01239472404796762, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": -2.2066, \"times_seen\": 1.0}, {\"site\": 825, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"828\", \"functional effect\": -1.3233, \"times_seen\": null}, {\"site\": 826, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 826, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 826, \"mutant\": \"D\", \"escape\": 0.016861684671180308, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 826, \"mutant\": \"L\", \"escape\": -0.15199036286165557, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -0.4038, \"times_seen\": 20.0}, {\"site\": 826, \"mutant\": \"P\", \"escape\": -0.0035414372111338814, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -1.0234, \"times_seen\": 1.0}, {\"site\": 826, \"mutant\": \"Q\", \"escape\": 0.01538529651247616, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.0163, \"times_seen\": 4.0}, {\"site\": 826, \"mutant\": \"S\", \"escape\": 0.008041280529750283, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.0185, \"times_seen\": 53.0}, {\"site\": 826, \"mutant\": \"T\", \"escape\": -0.01870374826854135, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": 0.059, \"times_seen\": 60.0}, {\"site\": 826, \"mutant\": \"V\", \"escape\": 0.1035010854515041, \"epitope\": \"epitope 1\", \"reference_site\": \"829\", \"functional effect\": -0.3378, \"times_seen\": 95.0}, {\"site\": 827, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 827, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 827, \"mutant\": \"E\", \"escape\": -2.9019574884596273, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.7465, \"times_seen\": 18.0}, {\"site\": 827, \"mutant\": \"G\", \"escape\": -0.2168671739229911, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.7345, \"times_seen\": 41.0}, {\"site\": 827, \"mutant\": \"H\", \"escape\": -0.010199384340663505, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.7527, \"times_seen\": 3.0}, {\"site\": 827, \"mutant\": \"N\", \"escape\": -0.07759498952753507, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -0.3931, \"times_seen\": 32.0}, {\"site\": 827, \"mutant\": \"Q\", \"escape\": 0.008865582523522361, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.811, \"times_seen\": 5.0}, {\"site\": 827, \"mutant\": \"R\", \"escape\": -0.01365936251783809, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -2.2549, \"times_seen\": 2.0}, {\"site\": 827, \"mutant\": \"T\", \"escape\": -0.011044337369835792, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.3214, \"times_seen\": 5.0}, {\"site\": 827, \"mutant\": \"Y\", \"escape\": 0.009541200781234325, \"epitope\": \"epitope 1\", \"reference_site\": \"830\", \"functional effect\": -1.3884, \"times_seen\": 22.0}, {\"site\": 828, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -1.3054, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"D\", \"escape\": -0.007011131982245098, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.3178, \"times_seen\": 8.0}, {\"site\": 828, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"K\", \"escape\": 0.008591374096162964, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -0.0031, \"times_seen\": 11.0}, {\"site\": 828, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -0.1246, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"S\", \"escape\": -0.04005141795522964, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.3553, \"times_seen\": 16.0}, {\"site\": 828, \"mutant\": \"T\", \"escape\": -0.2904081505378909, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": 0.0957, \"times_seen\": 74.0}, {\"site\": 828, \"mutant\": \"V\", \"escape\": -0.003879867499765904, \"epitope\": \"epitope 1\", \"reference_site\": \"831\", \"functional effect\": -0.7777, \"times_seen\": 42.0}, {\"site\": 829, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"A\", \"escape\": -0.0018381920584244855, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.0156, \"times_seen\": 1.0}, {\"site\": 829, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -2.6684, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"D\", \"escape\": -0.06942892810744995, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.1105, \"times_seen\": 49.0}, {\"site\": 829, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"N\", \"escape\": 0.018940267642033565, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.7725, \"times_seen\": 1.0}, {\"site\": 829, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -1.0359, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"S\", \"escape\": 0.28085763395433, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -0.731, \"times_seen\": 29.0}, {\"site\": 829, \"mutant\": \"V\", \"escape\": -0.020490990026947545, \"epitope\": \"epitope 1\", \"reference_site\": \"832\", \"functional effect\": -1.0164, \"times_seen\": 6.0}, {\"site\": 830, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 830, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 830, \"mutant\": \"H\", \"escape\": 0.006625710269295826, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -1.5015, \"times_seen\": 3.0}, {\"site\": 830, \"mutant\": \"I\", \"escape\": -0.02008845643183598, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.0113, \"times_seen\": 5.0}, {\"site\": 830, \"mutant\": \"L\", \"escape\": 0.020951777712628353, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": 0.1191, \"times_seen\": 16.0}, {\"site\": 830, \"mutant\": \"S\", \"escape\": -0.03323173534784876, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.1784, \"times_seen\": 12.0}, {\"site\": 830, \"mutant\": \"V\", \"escape\": -0.003550483080380585, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.0873, \"times_seen\": 1.0}, {\"site\": 830, \"mutant\": \"W\", \"escape\": -0.013060458296666015, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": -0.4468, \"times_seen\": 8.0}, {\"site\": 830, \"mutant\": \"Y\", \"escape\": -0.019283982979743583, \"epitope\": \"epitope 1\", \"reference_site\": \"833\", \"functional effect\": 0.098, \"times_seen\": 5.0}, {\"site\": 831, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 831, \"mutant\": \"F\", \"escape\": -0.03210662915979418, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.1099, \"times_seen\": 16.0}, {\"site\": 831, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 831, \"mutant\": \"L\", \"escape\": 0.07854289153131451, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.0544, \"times_seen\": 8.0}, {\"site\": 831, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -0.9074, \"times_seen\": null}, {\"site\": 831, \"mutant\": \"N\", \"escape\": 0.020213004889052404, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.1654, \"times_seen\": 17.0}, {\"site\": 831, \"mutant\": \"S\", \"escape\": -0.025776433770457473, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -0.1605, \"times_seen\": 6.0}, {\"site\": 831, \"mutant\": \"T\", \"escape\": -0.04490934894024477, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": -0.0861, \"times_seen\": 23.0}, {\"site\": 831, \"mutant\": \"V\", \"escape\": -0.0019559349515219323, \"epitope\": \"epitope 1\", \"reference_site\": \"834\", \"functional effect\": 0.3875, \"times_seen\": 15.0}, {\"site\": 832, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -2.0011, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"E\", \"escape\": -0.028875466540231414, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": 0.2586, \"times_seen\": 26.0}, {\"site\": 832, \"mutant\": \"H\", \"escape\": 0.0011861582980213195, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.5358, \"times_seen\": 4.0}, {\"site\": 832, \"mutant\": \"I\", \"escape\": -0.01380756040481994, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.2355, \"times_seen\": 5.0}, {\"site\": 832, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -1.8672, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"N\", \"escape\": -0.015028433504235635, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.5423, \"times_seen\": 10.0}, {\"site\": 832, \"mutant\": \"Q\", \"escape\": 0.050944094064888645, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.4526, \"times_seen\": 13.0}, {\"site\": 832, \"mutant\": \"R\", \"escape\": 0.01094674818396374, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.0165, \"times_seen\": 61.0}, {\"site\": 832, \"mutant\": \"T\", \"escape\": 0.0017717635507511012, \"epitope\": \"epitope 1\", \"reference_site\": \"835\", \"functional effect\": -0.0234, \"times_seen\": 10.0}, {\"site\": 833, \"mutant\": \"*\", \"escape\": 0.02288495455049004, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -2.9421, \"times_seen\": 1.0}, {\"site\": 833, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 833, \"mutant\": \"E\", \"escape\": 0.011478610288183255, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.1667, \"times_seen\": 16.0}, {\"site\": 833, \"mutant\": \"H\", \"escape\": 0.7362450083566198, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.4189, \"times_seen\": 47.0}, {\"site\": 833, \"mutant\": \"K\", \"escape\": -0.022071689665535046, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.2839, \"times_seen\": 15.0}, {\"site\": 833, \"mutant\": \"L\", \"escape\": 0.07398811164909581, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": 0.1973, \"times_seen\": 37.0}, {\"site\": 833, \"mutant\": \"M\", \"escape\": -0.03181085441794014, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": 0.3236, \"times_seen\": 7.0}, {\"site\": 833, \"mutant\": \"P\", \"escape\": 0.006676081560781507, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.4693, \"times_seen\": 8.0}, {\"site\": 833, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 833, \"mutant\": \"R\", \"escape\": -0.04901840029787046, \"epitope\": \"epitope 1\", \"reference_site\": \"836\", \"functional effect\": -0.1702, \"times_seen\": 23.0}, {\"site\": 834, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -2.8644, \"times_seen\": null}, {\"site\": 834, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 834, \"mutant\": \"C\", \"escape\": 0.013842692232091117, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -2.569, \"times_seen\": 3.0}, {\"site\": 834, \"mutant\": \"F\", \"escape\": -0.11241051500724625, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -0.1285, \"times_seen\": 21.0}, {\"site\": 834, \"mutant\": \"H\", \"escape\": -0.01776711321799748, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -0.2107, \"times_seen\": 12.0}, {\"site\": 834, \"mutant\": \"L\", \"escape\": -0.011494681266775343, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -1.874, \"times_seen\": 4.0}, {\"site\": 834, \"mutant\": \"N\", \"escape\": 0.01583318621943076, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -0.9393, \"times_seen\": 2.0}, {\"site\": 834, \"mutant\": \"S\", \"escape\": -0.0039039011673642435, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": -2.1686, \"times_seen\": 1.0}, {\"site\": 834, \"mutant\": \"W\", \"escape\": -0.0029008656859896187, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": 0.0472, \"times_seen\": 9.0}, {\"site\": 834, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"837\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -2.4752, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"A\", \"escape\": -0.012829791939534204, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 835, \"mutant\": \"C\", \"escape\": 1.7945220236655157, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -1.8205, \"times_seen\": 3.0}, {\"site\": 835, \"mutant\": \"D\", \"escape\": -0.03273377847817538, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.0613, \"times_seen\": 24.0}, {\"site\": 835, \"mutant\": \"E\", \"escape\": -0.08371723051150783, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.3981, \"times_seen\": 21.0}, {\"site\": 835, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"L\", \"escape\": 0.0015062807893431432, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -1.2886, \"times_seen\": 2.0}, {\"site\": 835, \"mutant\": \"R\", \"escape\": -0.13957058732842065, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.3667, \"times_seen\": 36.0}, {\"site\": 835, \"mutant\": \"S\", \"escape\": -0.025239515990353203, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": 0.3395, \"times_seen\": 21.0}, {\"site\": 835, \"mutant\": \"V\", \"escape\": 0.011948059893429116, \"epitope\": \"epitope 1\", \"reference_site\": \"838\", \"functional effect\": -0.8123, \"times_seen\": 5.0}, {\"site\": 836, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 836, \"mutant\": \"A\", \"escape\": 0.0030422947539993184, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.9998, \"times_seen\": 2.0}, {\"site\": 836, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 836, \"mutant\": \"E\", \"escape\": 0.08660926264243106, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.4425, \"times_seen\": 31.0}, {\"site\": 836, \"mutant\": \"G\", \"escape\": 1.3532420110730685, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.9107, \"times_seen\": 21.0}, {\"site\": 836, \"mutant\": \"H\", \"escape\": 0.0055932075730205965, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.3722, \"times_seen\": 1.0}, {\"site\": 836, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.6005, \"times_seen\": null}, {\"site\": 836, \"mutant\": \"N\", \"escape\": 0.03265388941922574, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.0207, \"times_seen\": 28.0}, {\"site\": 836, \"mutant\": \"S\", \"escape\": -0.01658904001637515, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.0149, \"times_seen\": 7.0}, {\"site\": 836, \"mutant\": \"T\", \"escape\": -0.004832224335467754, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.6912, \"times_seen\": 4.0}, {\"site\": 836, \"mutant\": \"V\", \"escape\": -0.029171155752994327, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -1.0975, \"times_seen\": 11.0}, {\"site\": 836, \"mutant\": \"Y\", \"escape\": 0.024791550354036858, \"epitope\": \"epitope 1\", \"reference_site\": \"839\", \"functional effect\": -0.5629, \"times_seen\": 24.0}, {\"site\": 837, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 837, \"mutant\": \"A\", \"escape\": -0.003173442259483354, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.8542, \"times_seen\": 1.0}, {\"site\": 837, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 837, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -1.6807, \"times_seen\": null}, {\"site\": 837, \"mutant\": \"G\", \"escape\": -0.008835101944506159, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.2287, \"times_seen\": 3.0}, {\"site\": 837, \"mutant\": \"R\", \"escape\": -0.004159419666129676, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -1.4463, \"times_seen\": 1.0}, {\"site\": 837, \"mutant\": \"S\", \"escape\": -0.012104648764475234, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.8114, \"times_seen\": 4.0}, {\"site\": 837, \"mutant\": \"Y\", \"escape\": 0.009830663667543099, \"epitope\": \"epitope 1\", \"reference_site\": \"840\", \"functional effect\": -2.6818, \"times_seen\": 4.0}, {\"site\": 838, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 838, \"mutant\": \"F\", \"escape\": -0.014565905234873944, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": 0.0767, \"times_seen\": 28.0}, {\"site\": 838, \"mutant\": \"I\", \"escape\": -0.03875289027728414, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.1726, \"times_seen\": 30.0}, {\"site\": 838, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 838, \"mutant\": \"M\", \"escape\": -0.01048178056076038, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.2628, \"times_seen\": 6.0}, {\"site\": 838, \"mutant\": \"N\", \"escape\": 0.01620896977560869, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -1.1094, \"times_seen\": 10.0}, {\"site\": 838, \"mutant\": \"P\", \"escape\": -0.014505892109059925, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -2.31, \"times_seen\": 2.0}, {\"site\": 838, \"mutant\": \"Q\", \"escape\": -0.007990116907347793, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.888, \"times_seen\": 1.0}, {\"site\": 838, \"mutant\": \"R\", \"escape\": -2.581615072116851, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.6282, \"times_seen\": 16.0}, {\"site\": 838, \"mutant\": \"V\", \"escape\": -0.007839597285115083, \"epitope\": \"epitope 1\", \"reference_site\": \"841\", \"functional effect\": -0.2603, \"times_seen\": 11.0}, {\"site\": 839, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -3.0653, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.7771, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"C\", \"escape\": -0.008106573328776312, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.6956, \"times_seen\": 4.0}, {\"site\": 839, \"mutant\": \"D\", \"escape\": 0.02457147406246563, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.1825, \"times_seen\": 48.0}, {\"site\": 839, \"mutant\": \"E\", \"escape\": 0.057643758920556405, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.054, \"times_seen\": 16.0}, {\"site\": 839, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"N\", \"escape\": 0.041450394892004715, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.1613, \"times_seen\": 17.0}, {\"site\": 839, \"mutant\": \"R\", \"escape\": -0.09303927979990188, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": 0.4444, \"times_seen\": 21.0}, {\"site\": 839, \"mutant\": \"S\", \"escape\": -0.04266425473954863, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.0344, \"times_seen\": 21.0}, {\"site\": 839, \"mutant\": \"V\", \"escape\": 0.05890968428223653, \"epitope\": \"epitope 1\", \"reference_site\": \"842\", \"functional effect\": -0.1463, \"times_seen\": 48.0}, {\"site\": 840, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"A\", \"escape\": 0.03513862230371803, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.0316, \"times_seen\": 8.0}, {\"site\": 840, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"E\", \"escape\": 0.06244341785022607, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.0822, \"times_seen\": 5.0}, {\"site\": 840, \"mutant\": \"G\", \"escape\": -0.03699966135629626, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.1265, \"times_seen\": 22.0}, {\"site\": 840, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -3.2587, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"I\", \"escape\": 0.005845967081821026, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.8541, \"times_seen\": 23.0}, {\"site\": 840, \"mutant\": \"M\", \"escape\": -0.07338201421058807, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.305, \"times_seen\": 12.0}, {\"site\": 840, \"mutant\": \"N\", \"escape\": 0.03735379784001581, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": 0.0364, \"times_seen\": 62.0}, {\"site\": 840, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -3.0689, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"Y\", \"escape\": -0.024037534256360703, \"epitope\": \"epitope 1\", \"reference_site\": \"843\", \"functional effect\": -0.6549, \"times_seen\": 16.0}, {\"site\": 841, \"mutant\": \"F\", \"escape\": -0.002137356712827161, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.5269, \"times_seen\": 9.0}, {\"site\": 841, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 841, \"mutant\": \"L\", \"escape\": 0.026255089279376528, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.11, \"times_seen\": 6.0}, {\"site\": 841, \"mutant\": \"M\", \"escape\": -0.042516064298157116, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.1671, \"times_seen\": 31.0}, {\"site\": 841, \"mutant\": \"N\", \"escape\": 0.012448984407931256, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.4068, \"times_seen\": 4.0}, {\"site\": 841, \"mutant\": \"S\", \"escape\": -0.015206764863545677, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.8194, \"times_seen\": 8.0}, {\"site\": 841, \"mutant\": \"T\", \"escape\": -0.06998528234155177, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.5731, \"times_seen\": 22.0}, {\"site\": 841, \"mutant\": \"V\", \"escape\": -0.04103067943107327, \"epitope\": \"epitope 1\", \"reference_site\": \"844\", \"functional effect\": -0.1602, \"times_seen\": 26.0}, {\"site\": 842, \"mutant\": \"*\", \"escape\": 0.03446691748934294, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -3.0735, \"times_seen\": 3.0}, {\"site\": 842, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 842, \"mutant\": \"C\", \"escape\": -0.0036504419035798025, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -2.6345, \"times_seen\": 22.0}, {\"site\": 842, \"mutant\": \"D\", \"escape\": 0.2948650804598568, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.1338, \"times_seen\": 60.0}, {\"site\": 842, \"mutant\": \"E\", \"escape\": -0.13389015438168547, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.6906, \"times_seen\": 42.0}, {\"site\": 842, \"mutant\": \"F\", \"escape\": -0.27280343127579904, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.4706, \"times_seen\": 24.0}, {\"site\": 842, \"mutant\": \"G\", \"escape\": 0.0035981841757161937, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.2424, \"times_seen\": 131.0}, {\"site\": 842, \"mutant\": \"H\", \"escape\": 0.4601812649967156, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.777, \"times_seen\": 25.0}, {\"site\": 842, \"mutant\": \"I\", \"escape\": 0.022749894766718678, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.1839, \"times_seen\": 41.0}, {\"site\": 842, \"mutant\": \"K\", \"escape\": -0.0029257604414355547, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.6403, \"times_seen\": 30.0}, {\"site\": 842, \"mutant\": \"L\", \"escape\": -1.6025988226020167, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.7181, \"times_seen\": 72.0}, {\"site\": 842, \"mutant\": \"M\", \"escape\": -0.05805351320899326, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.1965, \"times_seen\": 30.0}, {\"site\": 842, \"mutant\": \"N\", \"escape\": 0.028171965377162905, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9794, \"times_seen\": 41.0}, {\"site\": 842, \"mutant\": \"P\", \"escape\": 0.04263688538913936, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.4868, \"times_seen\": 44.0}, {\"site\": 842, \"mutant\": \"Q\", \"escape\": 0.039612026978413456, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9328, \"times_seen\": 33.0}, {\"site\": 842, \"mutant\": \"R\", \"escape\": 0.3745726789009493, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.2054, \"times_seen\": 111.0}, {\"site\": 842, \"mutant\": \"S\", \"escape\": 0.15165528364704464, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.5428, \"times_seen\": 157.0}, {\"site\": 842, \"mutant\": \"T\", \"escape\": 0.4013310394295238, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9665, \"times_seen\": 122.0}, {\"site\": 842, \"mutant\": \"V\", \"escape\": 0.09606032522815475, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -0.9245, \"times_seen\": 183.0}, {\"site\": 842, \"mutant\": \"W\", \"escape\": 0.06400545002318134, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.6397, \"times_seen\": 21.0}, {\"site\": 842, \"mutant\": \"Y\", \"escape\": -0.36251686836997715, \"epitope\": \"epitope 1\", \"reference_site\": \"845\", \"functional effect\": -1.367, \"times_seen\": 24.0}, {\"site\": 843, \"mutant\": \"*\", \"escape\": -0.01997853561936113, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.5419, \"times_seen\": 10.0}, {\"site\": 843, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.7207, \"times_seen\": null}, {\"site\": 843, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 843, \"mutant\": \"C\", \"escape\": 0.027979463479966285, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.79, \"times_seen\": 8.0}, {\"site\": 843, \"mutant\": \"D\", \"escape\": -0.059568518275891214, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.749, \"times_seen\": 29.0}, {\"site\": 843, \"mutant\": \"E\", \"escape\": 0.02622759374034197, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.0106, \"times_seen\": 29.0}, {\"site\": 843, \"mutant\": \"F\", \"escape\": 1.5699724065200886, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.4673, \"times_seen\": 22.0}, {\"site\": 843, \"mutant\": \"G\", \"escape\": 0.009072534745541629, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.0724, \"times_seen\": 152.0}, {\"site\": 843, \"mutant\": \"H\", \"escape\": 0.006627326611007644, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.6658, \"times_seen\": 25.0}, {\"site\": 843, \"mutant\": \"I\", \"escape\": 0.03273101155771825, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -0.9476, \"times_seen\": 27.0}, {\"site\": 843, \"mutant\": \"K\", \"escape\": 0.6166667724047408, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.8952, \"times_seen\": 15.0}, {\"site\": 843, \"mutant\": \"L\", \"escape\": 0.4003756688582735, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.2763, \"times_seen\": 74.0}, {\"site\": 843, \"mutant\": \"M\", \"escape\": -0.2168513712314938, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.2994, \"times_seen\": 27.0}, {\"site\": 843, \"mutant\": \"N\", \"escape\": -0.0006999699736859636, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -2.338, \"times_seen\": 19.0}, {\"site\": 843, \"mutant\": \"P\", \"escape\": -0.028534890108925903, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -0.0578, \"times_seen\": 64.0}, {\"site\": 843, \"mutant\": \"Q\", \"escape\": 0.030156322722887926, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.8253, \"times_seen\": 23.0}, {\"site\": 843, \"mutant\": \"R\", \"escape\": -0.10492860130507962, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.6611, \"times_seen\": 90.0}, {\"site\": 843, \"mutant\": \"S\", \"escape\": -0.47242043063398315, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.6539, \"times_seen\": 134.0}, {\"site\": 843, \"mutant\": \"T\", \"escape\": -0.00891461888366087, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.208, \"times_seen\": 117.0}, {\"site\": 843, \"mutant\": \"V\", \"escape\": 0.4433406579501864, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -0.3525, \"times_seen\": 118.0}, {\"site\": 843, \"mutant\": \"W\", \"escape\": 0.4523862140492579, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.5017, \"times_seen\": 24.0}, {\"site\": 843, \"mutant\": \"Y\", \"escape\": 0.05494809550919714, \"epitope\": \"epitope 1\", \"reference_site\": \"846\", \"functional effect\": -1.3419, \"times_seen\": 17.0}, {\"site\": 844, \"mutant\": \"G\", \"escape\": -0.02790851658114967, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.5694, \"times_seen\": 12.0}, {\"site\": 844, \"mutant\": \"I\", \"escape\": -0.020159237529258592, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.5871, \"times_seen\": 10.0}, {\"site\": 844, \"mutant\": \"K\", \"escape\": -0.1031397622790935, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -0.6712, \"times_seen\": 39.0}, {\"site\": 844, \"mutant\": \"L\", \"escape\": 0.03667092031737604, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.5409, \"times_seen\": 14.0}, {\"site\": 844, \"mutant\": \"M\", \"escape\": 0.03447232585369052, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.2483, \"times_seen\": 4.0}, {\"site\": 844, \"mutant\": \"N\", \"escape\": 0.03286698888122826, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.5557, \"times_seen\": 16.0}, {\"site\": 844, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 844, \"mutant\": \"S\", \"escape\": 0.01703143577604582, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.5772, \"times_seen\": 9.0}, {\"site\": 844, \"mutant\": \"T\", \"escape\": -0.036967173291168574, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -2.6551, \"times_seen\": 10.0}, {\"site\": 844, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"847\", \"functional effect\": -1.9387, \"times_seen\": null}, {\"site\": 845, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 845, \"mutant\": \"E\", \"escape\": 0.033325858088856394, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.2437, \"times_seen\": 31.0}, {\"site\": 845, \"mutant\": \"G\", \"escape\": 0.4460051539519371, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.9922, \"times_seen\": 9.0}, {\"site\": 845, \"mutant\": \"N\", \"escape\": 0.09942685481626531, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.7239, \"times_seen\": 27.0}, {\"site\": 845, \"mutant\": \"P\", \"escape\": 0.1147008455087955, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.7619, \"times_seen\": 6.0}, {\"site\": 845, \"mutant\": \"V\", \"escape\": -0.008167222839611, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.879, \"times_seen\": 5.0}, {\"site\": 845, \"mutant\": \"Y\", \"escape\": -0.0020218057888236438, \"epitope\": \"epitope 1\", \"reference_site\": \"848\", \"functional effect\": -2.8739, \"times_seen\": 2.0}, {\"site\": 846, \"mutant\": \"F\", \"escape\": -0.02425883087724189, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.2632, \"times_seen\": 19.0}, {\"site\": 846, \"mutant\": \"H\", \"escape\": -0.0009033903676773736, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.4326, \"times_seen\": 10.0}, {\"site\": 846, \"mutant\": \"I\", \"escape\": 0.0594999650363778, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -1.7226, \"times_seen\": 33.0}, {\"site\": 846, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 846, \"mutant\": \"M\", \"escape\": 0.008333311799075514, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -1.5231, \"times_seen\": 36.0}, {\"site\": 846, \"mutant\": \"P\", \"escape\": 0.28267698772658956, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.7332, \"times_seen\": 32.0}, {\"site\": 846, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -2.5052, \"times_seen\": null}, {\"site\": 846, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"849\", \"functional effect\": -3.1951, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"F\", \"escape\": -0.04240424202027785, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -0.5665, \"times_seen\": 15.0}, {\"site\": 847, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -3.2539, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"L\", \"escape\": -0.09058701737205184, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -0.7579, \"times_seen\": 37.0}, {\"site\": 847, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -2.5485, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"N\", \"escape\": -0.008784248841678298, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -2.5023, \"times_seen\": 3.0}, {\"site\": 847, \"mutant\": \"S\", \"escape\": -0.004087688930599454, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -1.3863, \"times_seen\": 1.0}, {\"site\": 847, \"mutant\": \"T\", \"escape\": 0.017475437340823536, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -1.5783, \"times_seen\": 7.0}, {\"site\": 847, \"mutant\": \"V\", \"escape\": -0.037221016557839125, \"epitope\": \"epitope 1\", \"reference_site\": \"850\", \"functional effect\": -0.7984, \"times_seen\": 38.0}, {\"site\": 848, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.9615, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.5732, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"I\", \"escape\": -0.008346959995801454, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.8686, \"times_seen\": 3.0}, {\"site\": 848, \"mutant\": \"L\", \"escape\": -0.0025644071917757714, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.9829, \"times_seen\": 2.0}, {\"site\": 848, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.4251, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -2.5641, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"V\", \"escape\": -0.0017476025976324075, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -3.064, \"times_seen\": 1.0}, {\"site\": 848, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"851\", \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 849, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 849, \"mutant\": \"D\", \"escape\": -0.010944684200974086, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -2.2183, \"times_seen\": 1.0}, {\"site\": 849, \"mutant\": \"G\", \"escape\": 0.022437272077177692, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -1.4741, \"times_seen\": 16.0}, {\"site\": 849, \"mutant\": \"H\", \"escape\": 0.0011658485140800397, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -1.7418, \"times_seen\": 12.0}, {\"site\": 849, \"mutant\": \"L\", \"escape\": 0.0016407234216832722, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": 0.1227, \"times_seen\": 6.0}, {\"site\": 849, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -1.3309, \"times_seen\": null}, {\"site\": 849, \"mutant\": \"S\", \"escape\": -0.10356896298059053, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -0.76, \"times_seen\": 32.0}, {\"site\": 849, \"mutant\": \"T\", \"escape\": -0.6232834595692041, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": -0.281, \"times_seen\": 62.0}, {\"site\": 849, \"mutant\": \"V\", \"escape\": -0.10408498835065352, \"epitope\": \"epitope 1\", \"reference_site\": \"852\", \"functional effect\": 0.0462, \"times_seen\": 58.0}, {\"site\": 850, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -2.661, \"times_seen\": null}, {\"site\": 850, \"mutant\": \"E\", \"escape\": -0.007030324691527414, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.5227, \"times_seen\": 15.0}, {\"site\": 850, \"mutant\": \"H\", \"escape\": -0.021681567398281084, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.1194, \"times_seen\": 16.0}, {\"site\": 850, \"mutant\": \"K\", \"escape\": -0.011394881738258112, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -1.3369, \"times_seen\": 24.0}, {\"site\": 850, \"mutant\": \"L\", \"escape\": 0.016270316680639565, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.1023, \"times_seen\": 15.0}, {\"site\": 850, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -1.5723, \"times_seen\": null}, {\"site\": 850, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 850, \"mutant\": \"R\", \"escape\": -0.0020428799914221927, \"epitope\": \"epitope 1\", \"reference_site\": \"853\", \"functional effect\": -0.2598, \"times_seen\": 27.0}, {\"site\": 851, \"mutant\": \"*\", \"escape\": 0.0008616092539516717, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -1.312, \"times_seen\": 1.0}, {\"site\": 851, \"mutant\": \"E\", \"escape\": -0.010340355350255768, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -2.41, \"times_seen\": 9.0}, {\"site\": 851, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 851, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 851, \"mutant\": \"N\", \"escape\": 0.011012721690405103, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -2.0602, \"times_seen\": 20.0}, {\"site\": 851, \"mutant\": \"Q\", \"escape\": -0.06012042482763213, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -1.6936, \"times_seen\": 15.0}, {\"site\": 851, \"mutant\": \"R\", \"escape\": -0.04559206540495778, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -0.1584, \"times_seen\": 27.0}, {\"site\": 851, \"mutant\": \"S\", \"escape\": -0.008319615876908, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -2.4184, \"times_seen\": 3.0}, {\"site\": 851, \"mutant\": \"T\", \"escape\": -0.05132562853295498, \"epitope\": \"epitope 1\", \"reference_site\": \"854\", \"functional effect\": -1.8308, \"times_seen\": 8.0}, {\"site\": 852, \"mutant\": \"C\", \"escape\": -0.006660894963173905, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -2.5032, \"times_seen\": 1.0}, {\"site\": 852, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 852, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -1.965, \"times_seen\": null}, {\"site\": 852, \"mutant\": \"L\", \"escape\": -0.3615565035896998, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": 0.3644, \"times_seen\": 38.0}, {\"site\": 852, \"mutant\": \"S\", \"escape\": 0.05994661880740645, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -0.5995, \"times_seen\": 73.0}, {\"site\": 852, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -2.4708, \"times_seen\": null}, {\"site\": 852, \"mutant\": \"Y\", \"escape\": -0.001757665395492698, \"epitope\": \"epitope 1\", \"reference_site\": \"855\", \"functional effect\": -1.4274, \"times_seen\": 6.0}, {\"site\": 853, \"mutant\": \"*\", \"escape\": 0.008057666869424282, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.8102, \"times_seen\": 5.0}, {\"site\": 853, \"mutant\": \"-\", \"escape\": 1.886809554033191, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.5312, \"times_seen\": 1.0}, {\"site\": 853, \"mutant\": \"A\", \"escape\": 0.4404827192276912, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.9125, \"times_seen\": 92.0}, {\"site\": 853, \"mutant\": \"C\", \"escape\": 0.0035512050646145546, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -1.5977, \"times_seen\": 26.0}, {\"site\": 853, \"mutant\": \"D\", \"escape\": -0.007295992280405269, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.5873, \"times_seen\": 3.0}, {\"site\": 853, \"mutant\": \"E\", \"escape\": -0.018890262884015886, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.3979, \"times_seen\": 15.0}, {\"site\": 853, \"mutant\": \"F\", \"escape\": -0.04275070623908855, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.1267, \"times_seen\": 41.0}, {\"site\": 853, \"mutant\": \"G\", \"escape\": -0.02681663846751803, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.3544, \"times_seen\": 14.0}, {\"site\": 853, \"mutant\": \"H\", \"escape\": -0.08813654008819566, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": 0.0791, \"times_seen\": 70.0}, {\"site\": 853, \"mutant\": \"I\", \"escape\": 0.008218135470872199, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.1387, \"times_seen\": 18.0}, {\"site\": 853, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 853, \"mutant\": \"L\", \"escape\": -0.05599832415887889, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.0955, \"times_seen\": 61.0}, {\"site\": 853, \"mutant\": \"M\", \"escape\": -0.39429123675686595, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.4447, \"times_seen\": 16.0}, {\"site\": 853, \"mutant\": \"N\", \"escape\": 0.11132323257671133, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -1.7298, \"times_seen\": 64.0}, {\"site\": 853, \"mutant\": \"P\", \"escape\": 0.004314566215831633, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.5298, \"times_seen\": 14.0}, {\"site\": 853, \"mutant\": \"Q\", \"escape\": 0.0022999929613832753, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.2424, \"times_seen\": 17.0}, {\"site\": 853, \"mutant\": \"R\", \"escape\": 0.06159504992767754, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.6447, \"times_seen\": 224.0}, {\"site\": 853, \"mutant\": \"S\", \"escape\": -0.41411472395040816, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -1.9095, \"times_seen\": 79.0}, {\"site\": 853, \"mutant\": \"T\", \"escape\": -0.0018017992062424409, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -2.1544, \"times_seen\": 24.0}, {\"site\": 853, \"mutant\": \"V\", \"escape\": -0.17514599333990918, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.8934, \"times_seen\": 83.0}, {\"site\": 853, \"mutant\": \"W\", \"escape\": 0.021235778381609935, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.3892, \"times_seen\": 43.0}, {\"site\": 853, \"mutant\": \"Y\", \"escape\": 0.11811623101427403, \"epitope\": \"epitope 1\", \"reference_site\": \"856\", \"functional effect\": -0.8007, \"times_seen\": 50.0}, {\"site\": 854, \"mutant\": \"*\", \"escape\": -0.0037313979407987015, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -2.1181, \"times_seen\": 1.0}, {\"site\": 854, \"mutant\": \"A\", \"escape\": 0.0006627606368458729, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -2.9628, \"times_seen\": 2.0}, {\"site\": 854, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -3.0382, \"times_seen\": null}, {\"site\": 854, \"mutant\": \"E\", \"escape\": -0.0008428888704308569, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -1.1154, \"times_seen\": 1.0}, {\"site\": 854, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 854, \"mutant\": \"R\", \"escape\": -0.0035608522888971174, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -2.289, \"times_seen\": 1.0}, {\"site\": 854, \"mutant\": \"S\", \"escape\": -0.004232142556440996, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -1.0823, \"times_seen\": 2.0}, {\"site\": 854, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"857\", \"functional effect\": -3.0362, \"times_seen\": null}, {\"site\": 855, \"mutant\": \"C\", \"escape\": 0.0017191041695073684, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -2.5774, \"times_seen\": 1.0}, {\"site\": 855, \"mutant\": \"F\", \"escape\": -0.03686809369366393, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -2.1564, \"times_seen\": 24.0}, {\"site\": 855, \"mutant\": \"H\", \"escape\": 0.011324878359250615, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -2.7938, \"times_seen\": 2.0}, {\"site\": 855, \"mutant\": \"I\", \"escape\": 0.024410118725032712, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": 0.4444, \"times_seen\": 39.0}, {\"site\": 855, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 855, \"mutant\": \"M\", \"escape\": -0.00866915558042034, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -0.3922, \"times_seen\": 3.0}, {\"site\": 855, \"mutant\": \"P\", \"escape\": -0.004474738106351447, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -1.7526, \"times_seen\": 2.0}, {\"site\": 855, \"mutant\": \"V\", \"escape\": 0.04485025132859849, \"epitope\": \"epitope 1\", \"reference_site\": \"858\", \"functional effect\": -0.1563, \"times_seen\": 18.0}, {\"site\": 856, \"mutant\": \"*\", \"escape\": -0.14641425356702992, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -2.6513, \"times_seen\": 8.0}, {\"site\": 856, \"mutant\": \"A\", \"escape\": -0.15939965175906454, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.5444, \"times_seen\": 104.0}, {\"site\": 856, \"mutant\": \"C\", \"escape\": -0.10878452503017347, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.5342, \"times_seen\": 15.0}, {\"site\": 856, \"mutant\": \"D\", \"escape\": -0.12640566289244373, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.6204, \"times_seen\": 27.0}, {\"site\": 856, \"mutant\": \"E\", \"escape\": 0.008337428957006924, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.2778, \"times_seen\": 11.0}, {\"site\": 856, \"mutant\": \"F\", \"escape\": -0.08465286458520589, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.4182, \"times_seen\": 26.0}, {\"site\": 856, \"mutant\": \"G\", \"escape\": -0.05490095476454329, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": 0.4027, \"times_seen\": 39.0}, {\"site\": 856, \"mutant\": \"H\", \"escape\": 0.213314818000321, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.7925, \"times_seen\": 35.0}, {\"site\": 856, \"mutant\": \"I\", \"escape\": -0.02061656311037013, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.5402, \"times_seen\": 73.0}, {\"site\": 856, \"mutant\": \"K\", \"escape\": 0.11513660339489845, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -2.407, \"times_seen\": 25.0}, {\"site\": 856, \"mutant\": \"L\", \"escape\": 0.03487705883664618, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.3142, \"times_seen\": 73.0}, {\"site\": 856, \"mutant\": \"M\", \"escape\": 0.3702484187373178, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.0852, \"times_seen\": 36.0}, {\"site\": 856, \"mutant\": \"N\", \"escape\": -0.034910625827819876, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.2957, \"times_seen\": 82.0}, {\"site\": 856, \"mutant\": \"P\", \"escape\": -0.018539165568740378, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -2.7071, \"times_seen\": 11.0}, {\"site\": 856, \"mutant\": \"Q\", \"escape\": -0.02855619217350914, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.4345, \"times_seen\": 27.0}, {\"site\": 856, \"mutant\": \"R\", \"escape\": -0.15250905076768795, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -1.6237, \"times_seen\": 60.0}, {\"site\": 856, \"mutant\": \"S\", \"escape\": -0.07845321524161776, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.0987, \"times_seen\": 123.0}, {\"site\": 856, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 856, \"mutant\": \"V\", \"escape\": 0.006333713476617552, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.8602, \"times_seen\": 67.0}, {\"site\": 856, \"mutant\": \"W\", \"escape\": -0.0804415279690536, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.871, \"times_seen\": 23.0}, {\"site\": 856, \"mutant\": \"Y\", \"escape\": -0.04389599544152487, \"epitope\": \"epitope 1\", \"reference_site\": \"859\", \"functional effect\": -0.9994, \"times_seen\": 38.0}, {\"site\": 857, \"mutant\": \"A\", \"escape\": -0.016775122030037965, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -0.6694, \"times_seen\": 6.0}, {\"site\": 857, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -2.9421, \"times_seen\": null}, {\"site\": 857, \"mutant\": \"F\", \"escape\": 0.3267333024181592, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 857, \"mutant\": \"I\", \"escape\": -0.001624328768098975, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.1868, \"times_seen\": 39.0}, {\"site\": 857, \"mutant\": \"L\", \"escape\": -0.07722282610833973, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.2905, \"times_seen\": 100.0}, {\"site\": 857, \"mutant\": \"M\", \"escape\": -0.6702881115013678, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.4342, \"times_seen\": 18.0}, {\"site\": 857, \"mutant\": \"Q\", \"escape\": 0.0692035382859614, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -0.421, \"times_seen\": 16.0}, {\"site\": 857, \"mutant\": \"S\", \"escape\": 0.004376457660476035, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": -1.7347, \"times_seen\": 7.0}, {\"site\": 857, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"860\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"C\", \"escape\": -0.033671552488731986, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -1.5722, \"times_seen\": 6.0}, {\"site\": 858, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"M\", \"escape\": 0.04363420576672146, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -0.4802, \"times_seen\": 16.0}, {\"site\": 858, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -2.1524, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -3.2746, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"S\", \"escape\": 0.02855776050035877, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -1.3433, \"times_seen\": 13.0}, {\"site\": 858, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"861\", \"functional effect\": -1.6898, \"times_seen\": null}, {\"site\": 859, \"mutant\": \"A\", \"escape\": 0.07167159872892681, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -0.7611, \"times_seen\": 24.0}, {\"site\": 859, \"mutant\": \"H\", \"escape\": -0.058233608815010475, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.0231, \"times_seen\": 15.0}, {\"site\": 859, \"mutant\": \"K\", \"escape\": -0.004242927676133789, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.3384, \"times_seen\": 3.0}, {\"site\": 859, \"mutant\": \"L\", \"escape\": -0.006621957366508363, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.0846, \"times_seen\": 4.0}, {\"site\": 859, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 859, \"mutant\": \"Q\", \"escape\": 0.009687588695566308, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -0.919, \"times_seen\": 5.0}, {\"site\": 859, \"mutant\": \"S\", \"escape\": -0.021197384812472794, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -1.0717, \"times_seen\": 33.0}, {\"site\": 859, \"mutant\": \"T\", \"escape\": -0.01682860515787206, \"epitope\": \"epitope 1\", \"reference_site\": \"862\", \"functional effect\": -0.7747, \"times_seen\": 17.0}, {\"site\": 860, \"mutant\": \"H\", \"escape\": -0.011403086905476475, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -1.96, \"times_seen\": 5.0}, {\"site\": 860, \"mutant\": \"L\", \"escape\": -0.04527329099955941, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -2.6658, \"times_seen\": 8.0}, {\"site\": 860, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 860, \"mutant\": \"Q\", \"escape\": -0.001061805990594157, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -0.6719, \"times_seen\": 1.0}, {\"site\": 860, \"mutant\": \"S\", \"escape\": -0.10913602047634785, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -0.9811, \"times_seen\": 17.0}, {\"site\": 860, \"mutant\": \"T\", \"escape\": -0.0032996164923602715, \"epitope\": \"epitope 1\", \"reference_site\": \"863\", \"functional effect\": -2.9445, \"times_seen\": 1.0}, {\"site\": 861, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 861, \"mutant\": \"F\", \"escape\": 0.029063192713823568, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.6214, \"times_seen\": 5.0}, {\"site\": 861, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 861, \"mutant\": \"M\", \"escape\": -0.011331767304275313, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -1.0673, \"times_seen\": 2.0}, {\"site\": 861, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.7403, \"times_seen\": null}, {\"site\": 861, \"mutant\": \"Q\", \"escape\": -0.010171402014192745, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -0.7441, \"times_seen\": 4.0}, {\"site\": 861, \"mutant\": \"V\", \"escape\": 0.0026419512152129456, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -1.5503, \"times_seen\": 13.0}, {\"site\": 861, \"mutant\": \"Y\", \"escape\": -0.009466047224044304, \"epitope\": \"epitope 1\", \"reference_site\": \"864\", \"functional effect\": -2.7774, \"times_seen\": 3.0}, {\"site\": 862, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"C\", \"escape\": 0.004637923035704908, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.018, \"times_seen\": 5.0}, {\"site\": 862, \"mutant\": \"F\", \"escape\": 0.0096572215010588, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -0.432, \"times_seen\": 24.0}, {\"site\": 862, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"M\", \"escape\": -0.0028130303026671264, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -0.1443, \"times_seen\": 3.0}, {\"site\": 862, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.9684, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"Q\", \"escape\": -0.013293284671299603, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -1.6943, \"times_seen\": 1.0}, {\"site\": 862, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -1.8793, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"865\", \"functional effect\": -2.3348, \"times_seen\": null}, {\"site\": 863, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -2.0678, \"times_seen\": null}, {\"site\": 863, \"mutant\": \"A\", \"escape\": -0.007871242971099991, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -1.8864, \"times_seen\": 4.0}, {\"site\": 863, \"mutant\": \"C\", \"escape\": -0.0057882988488150875, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -2.383, \"times_seen\": 2.0}, {\"site\": 863, \"mutant\": \"E\", \"escape\": -0.003208010668339155, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -1.4373, \"times_seen\": 1.0}, {\"site\": 863, \"mutant\": \"F\", \"escape\": -0.002564265383679135, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -3.0869, \"times_seen\": 1.0}, {\"site\": 863, \"mutant\": \"I\", \"escape\": -0.003925461027306572, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -2.9688, \"times_seen\": 2.0}, {\"site\": 863, \"mutant\": \"K\", \"escape\": 0.055950233512057884, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -0.8521, \"times_seen\": 4.0}, {\"site\": 863, \"mutant\": \"N\", \"escape\": -0.027477560796697227, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -0.8765, \"times_seen\": 21.0}, {\"site\": 863, \"mutant\": \"S\", \"escape\": 0.008670822836539265, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": -1.2687, \"times_seen\": 6.0}, {\"site\": 863, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"866\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"A\", \"escape\": -0.008752506367690134, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.1439, \"times_seen\": 5.0}, {\"site\": 864, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"E\", \"escape\": -0.11732527343672856, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.6771, \"times_seen\": 15.0}, {\"site\": 864, \"mutant\": \"G\", \"escape\": 0.029549775953369394, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -0.9305, \"times_seen\": 25.0}, {\"site\": 864, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"N\", \"escape\": -0.06447751186066053, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -0.5879, \"times_seen\": 47.0}, {\"site\": 864, \"mutant\": \"S\", \"escape\": -0.010654445143841553, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -0.928, \"times_seen\": 6.0}, {\"site\": 864, \"mutant\": \"T\", \"escape\": 0.027534139939869858, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.4787, \"times_seen\": 7.0}, {\"site\": 864, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -2.9937, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"Y\", \"escape\": -0.08400186082049549, \"epitope\": \"epitope 1\", \"reference_site\": \"867\", \"functional effect\": -1.1107, \"times_seen\": 51.0}, {\"site\": 865, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -2.9627, \"times_seen\": null}, {\"site\": 865, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 865, \"mutant\": \"A\", \"escape\": -0.004094351875250311, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": 0.4116, \"times_seen\": 11.0}, {\"site\": 865, \"mutant\": \"D\", \"escape\": 0.0023171997981061964, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.8784, \"times_seen\": 12.0}, {\"site\": 865, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 865, \"mutant\": \"G\", \"escape\": -0.6948265941569036, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.0776, \"times_seen\": 23.0}, {\"site\": 865, \"mutant\": \"K\", \"escape\": -0.07024417096436314, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.8603, \"times_seen\": 28.0}, {\"site\": 865, \"mutant\": \"L\", \"escape\": -0.021587410575623262, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.0227, \"times_seen\": 19.0}, {\"site\": 865, \"mutant\": \"Q\", \"escape\": 0.7786957630332239, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.1754, \"times_seen\": 16.0}, {\"site\": 865, \"mutant\": \"S\", \"escape\": 0.053369920952114916, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": 0.0639, \"times_seen\": 11.0}, {\"site\": 865, \"mutant\": \"T\", \"escape\": -0.023927612257206275, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.2828, \"times_seen\": 10.0}, {\"site\": 865, \"mutant\": \"V\", \"escape\": -0.051067221442370976, \"epitope\": \"epitope 1\", \"reference_site\": \"868\", \"functional effect\": -0.0615, \"times_seen\": 19.0}, {\"site\": 866, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 866, \"mutant\": \"F\", \"escape\": 0.0192379904208207, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.9106, \"times_seen\": 5.0}, {\"site\": 866, \"mutant\": \"I\", \"escape\": 0.005185859383315763, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -2.1834, \"times_seen\": 43.0}, {\"site\": 866, \"mutant\": \"K\", \"escape\": -0.0011021133142907296, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -2.8871, \"times_seen\": 1.0}, {\"site\": 866, \"mutant\": \"L\", \"escape\": -0.014011019158332687, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.9617, \"times_seen\": 13.0}, {\"site\": 866, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 866, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.1256, \"times_seen\": null}, {\"site\": 866, \"mutant\": \"T\", \"escape\": -0.0072248889927338175, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -2.0013, \"times_seen\": 2.0}, {\"site\": 866, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"869\", \"functional effect\": -1.6846, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"A\", \"escape\": -0.004697952433526097, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 867, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -3.029, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"K\", \"escape\": -0.038394878913485676, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -2.5393, \"times_seen\": 18.0}, {\"site\": 867, \"mutant\": \"L\", \"escape\": -0.002291390784162962, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -0.2995, \"times_seen\": 8.0}, {\"site\": 867, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -1.3361, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"N\", \"escape\": 0.009153893259954282, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -2.73, \"times_seen\": 3.0}, {\"site\": 867, \"mutant\": \"S\", \"escape\": 0.043213186197827276, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -1.9914, \"times_seen\": 7.0}, {\"site\": 867, \"mutant\": \"T\", \"escape\": -0.025525874757125176, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -1.265, \"times_seen\": 16.0}, {\"site\": 867, \"mutant\": \"V\", \"escape\": -0.6144766164708316, \"epitope\": \"epitope 1\", \"reference_site\": \"870\", \"functional effect\": -0.5048, \"times_seen\": 13.0}, {\"site\": 868, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"C\", \"escape\": 0.029967951388461752, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -0.8446, \"times_seen\": 16.0}, {\"site\": 868, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -2.4325, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.963, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"H\", \"escape\": -0.007294217214135531, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -2.239, \"times_seen\": 8.0}, {\"site\": 868, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.1637, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"S\", \"escape\": -0.02790251360799536, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.8396, \"times_seen\": 40.0}, {\"site\": 868, \"mutant\": \"T\", \"escape\": -0.06284082384843176, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -1.8136, \"times_seen\": 42.0}, {\"site\": 868, \"mutant\": \"V\", \"escape\": 0.48943086115462153, \"epitope\": \"epitope 1\", \"reference_site\": \"871\", \"functional effect\": -0.9823, \"times_seen\": 63.0}, {\"site\": 869, \"mutant\": \"*\", \"escape\": -0.009066656963337487, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -1.2791, \"times_seen\": 1.0}, {\"site\": 869, \"mutant\": \"H\", \"escape\": -0.014628955268623102, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -2.6765, \"times_seen\": 18.0}, {\"site\": 869, \"mutant\": \"K\", \"escape\": 0.018487871442248775, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -2.8286, \"times_seen\": 14.0}, {\"site\": 869, \"mutant\": \"L\", \"escape\": 0.008486220589957091, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 869, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 869, \"mutant\": \"R\", \"escape\": -0.0030717975113498256, \"epitope\": \"epitope 1\", \"reference_site\": \"872\", \"functional effect\": -2.8946, \"times_seen\": 11.0}, {\"site\": 870, \"mutant\": \"*\", \"escape\": 0.021653813163609925, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.8302, \"times_seen\": 2.0}, {\"site\": 870, \"mutant\": \"C\", \"escape\": 0.011458940608317382, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.2976, \"times_seen\": 5.0}, {\"site\": 870, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -3.2859, \"times_seen\": null}, {\"site\": 870, \"mutant\": \"H\", \"escape\": -0.018223654655356445, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.5511, \"times_seen\": 4.0}, {\"site\": 870, \"mutant\": \"L\", \"escape\": -0.009078105949446325, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.6485, \"times_seen\": 3.0}, {\"site\": 870, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.3176, \"times_seen\": null}, {\"site\": 870, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -3.0674, \"times_seen\": null}, {\"site\": 870, \"mutant\": \"S\", \"escape\": 0.020933699736668157, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": -2.876, \"times_seen\": 3.0}, {\"site\": 870, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"873\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 871, \"mutant\": \"A\", \"escape\": 0.023916791581088843, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -1.3152, \"times_seen\": 28.0}, {\"site\": 871, \"mutant\": \"I\", \"escape\": -0.7527748562445454, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.4757, \"times_seen\": 60.0}, {\"site\": 871, \"mutant\": \"L\", \"escape\": -0.005791970982877754, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 871, \"mutant\": \"N\", \"escape\": -0.05158356846450672, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -2.4005, \"times_seen\": 26.0}, {\"site\": 871, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.2002, \"times_seen\": null}, {\"site\": 871, \"mutant\": \"S\", \"escape\": 0.0015159110646809984, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.8241, \"times_seen\": 13.0}, {\"site\": 871, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 871, \"mutant\": \"V\", \"escape\": -0.004311660131021048, \"epitope\": \"epitope 1\", \"reference_site\": \"874\", \"functional effect\": -0.5853, \"times_seen\": 10.0}, {\"site\": 872, \"mutant\": \"A\", \"escape\": -0.03301824399412379, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 872, \"mutant\": \"D\", \"escape\": -0.0028232417766284306, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.9798, \"times_seen\": 5.0}, {\"site\": 872, \"mutant\": \"F\", \"escape\": 0.0021728389017353278, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.3565, \"times_seen\": 7.0}, {\"site\": 872, \"mutant\": \"P\", \"escape\": -0.015885992093958645, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.6843, \"times_seen\": 5.0}, {\"site\": 872, \"mutant\": \"Q\", \"escape\": 0.010756715591876862, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.8007, \"times_seen\": 6.0}, {\"site\": 872, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 872, \"mutant\": \"T\", \"escape\": -0.017035793393762266, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -1.976, \"times_seen\": 7.0}, {\"site\": 872, \"mutant\": \"Y\", \"escape\": -0.0039545955115703295, \"epitope\": \"epitope 1\", \"reference_site\": \"875\", \"functional effect\": -2.1349, \"times_seen\": 4.0}, {\"site\": 873, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 873, \"mutant\": \"C\", \"escape\": -0.001680241582135105, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -1.8838, \"times_seen\": 3.0}, {\"site\": 873, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -2.9101, \"times_seen\": null}, {\"site\": 873, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -2.995, \"times_seen\": null}, {\"site\": 873, \"mutant\": \"S\", \"escape\": -0.04287405563888731, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 873, \"mutant\": \"T\", \"escape\": 0.0015570285200420821, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -1.912, \"times_seen\": 18.0}, {\"site\": 873, \"mutant\": \"V\", \"escape\": 0.7290332069999209, \"epitope\": \"epitope 1\", \"reference_site\": \"876\", \"functional effect\": -2.9086, \"times_seen\": 20.0}, {\"site\": 874, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 874, \"mutant\": \"M\", \"escape\": -0.26264602767547474, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -0.3375, \"times_seen\": 23.0}, {\"site\": 874, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -2.9952, \"times_seen\": null}, {\"site\": 874, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -1.8158, \"times_seen\": null}, {\"site\": 874, \"mutant\": \"T\", \"escape\": -0.08199707008655774, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -2.0821, \"times_seen\": 4.0}, {\"site\": 874, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"877\", \"functional effect\": -1.083, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -2.1864, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"I\", \"escape\": -0.037379970198920205, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -0.2397, \"times_seen\": 19.0}, {\"site\": 875, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"M\", \"escape\": -0.0043593371423171065, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": 0.193, \"times_seen\": 2.0}, {\"site\": 875, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -1.5423, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -3.0457, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"S\", \"escape\": 0.07459125612950092, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 875, \"mutant\": \"V\", \"escape\": -0.025744799907949485, \"epitope\": \"epitope 1\", \"reference_site\": \"878\", \"functional effect\": -0.3973, \"times_seen\": 17.0}, {\"site\": 876, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 876, \"mutant\": \"C\", \"escape\": 0.02777009777459297, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -1.3348, \"times_seen\": 5.0}, {\"site\": 876, \"mutant\": \"D\", \"escape\": -0.010271936864982754, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -2.5662, \"times_seen\": 3.0}, {\"site\": 876, \"mutant\": \"F\", \"escape\": -0.0548930247356261, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -1.8807, \"times_seen\": 5.0}, {\"site\": 876, \"mutant\": \"G\", \"escape\": -0.011952130595615227, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -2.1241, \"times_seen\": 11.0}, {\"site\": 876, \"mutant\": \"H\", \"escape\": 0.14044305066336502, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -2.8638, \"times_seen\": 6.0}, {\"site\": 876, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -3.1006, \"times_seen\": null}, {\"site\": 876, \"mutant\": \"S\", \"escape\": -0.019964472511139815, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -0.6351, \"times_seen\": 23.0}, {\"site\": 876, \"mutant\": \"T\", \"escape\": -0.0930779008600194, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -1.6446, \"times_seen\": 62.0}, {\"site\": 876, \"mutant\": \"V\", \"escape\": -0.008042400663631077, \"epitope\": \"epitope 1\", \"reference_site\": \"879\", \"functional effect\": -0.8753, \"times_seen\": 50.0}, {\"site\": 877, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -1.703, \"times_seen\": null}, {\"site\": 877, \"mutant\": \"C\", \"escape\": -0.013065646895217057, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.5512, \"times_seen\": 5.0}, {\"site\": 877, \"mutant\": \"D\", \"escape\": 0.01775358692797411, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.8455, \"times_seen\": 4.0}, {\"site\": 877, \"mutant\": \"F\", \"escape\": 0.029785981631231983, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.9677, \"times_seen\": 4.0}, {\"site\": 877, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 877, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -3.1228, \"times_seen\": null}, {\"site\": 877, \"mutant\": \"S\", \"escape\": -0.0034751634302399056, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.2973, \"times_seen\": 1.0}, {\"site\": 877, \"mutant\": \"V\", \"escape\": -0.004212899254242627, \"epitope\": \"epitope 1\", \"reference_site\": \"880\", \"functional effect\": -2.0185, \"times_seen\": 2.0}, {\"site\": 878, \"mutant\": \"A\", \"escape\": 0.4668352204012127, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -1.2638, \"times_seen\": 35.0}, {\"site\": 878, \"mutant\": \"C\", \"escape\": 0.06480611555902806, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -1.4343, \"times_seen\": 13.0}, {\"site\": 878, \"mutant\": \"I\", \"escape\": -0.004318551049310211, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -0.3877, \"times_seen\": 36.0}, {\"site\": 878, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 878, \"mutant\": \"P\", \"escape\": -0.0016928059543988346, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -2.9447, \"times_seen\": 2.0}, {\"site\": 878, \"mutant\": \"R\", \"escape\": 0.0008673381553951961, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": -2.7151, \"times_seen\": 2.0}, {\"site\": 878, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"881\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -2.8883, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"L\", \"escape\": 0.0033445829331574775, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -0.3617, \"times_seen\": 15.0}, {\"site\": 879, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -3.1585, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -3.3372, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"T\", \"escape\": -0.01145751620108067, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -2.4807, \"times_seen\": 4.0}, {\"site\": 879, \"mutant\": \"V\", \"escape\": 0.019855515305216016, \"epitope\": \"epitope 1\", \"reference_site\": \"882\", \"functional effect\": -1.8263, \"times_seen\": 23.0}, {\"site\": 880, \"mutant\": \"A\", \"escape\": 0.08050146658018424, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -2.1703, \"times_seen\": 16.0}, {\"site\": 880, \"mutant\": \"I\", \"escape\": -0.4889148747318129, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": 0.1604, \"times_seen\": 66.0}, {\"site\": 880, \"mutant\": \"N\", \"escape\": -0.003963081951100121, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -1.9154, \"times_seen\": 1.0}, {\"site\": 880, \"mutant\": \"Q\", \"escape\": -0.001742086601230712, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -2.556, \"times_seen\": 5.0}, {\"site\": 880, \"mutant\": \"S\", \"escape\": 0.009907204393685191, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": -2.1828, \"times_seen\": 34.0}, {\"site\": 880, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 880, \"mutant\": \"V\", \"escape\": 0.025159753413616186, \"epitope\": \"epitope 1\", \"reference_site\": \"883\", \"functional effect\": 0.3069, \"times_seen\": 16.0}, {\"site\": 881, \"mutant\": \"A\", \"escape\": 0.000992128404994623, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.6929, \"times_seen\": 17.0}, {\"site\": 881, \"mutant\": \"C\", \"escape\": 0.1913531350568261, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.0416, \"times_seen\": 71.0}, {\"site\": 881, \"mutant\": \"F\", \"escape\": 0.011608255675088665, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.9622, \"times_seen\": 58.0}, {\"site\": 881, \"mutant\": \"P\", \"escape\": -0.0016717378040082551, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -3.0951, \"times_seen\": 3.0}, {\"site\": 881, \"mutant\": \"Q\", \"escape\": 0.008710104000592396, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -2.5014, \"times_seen\": 5.0}, {\"site\": 881, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 881, \"mutant\": \"T\", \"escape\": -0.0021801093944496495, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": 0.2088, \"times_seen\": 1.0}, {\"site\": 881, \"mutant\": \"Y\", \"escape\": -0.0156195986661041, \"epitope\": \"epitope 1\", \"reference_site\": \"884\", \"functional effect\": -0.6158, \"times_seen\": 5.0}, {\"site\": 882, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 882, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -2.766, \"times_seen\": null}, {\"site\": 882, \"mutant\": \"C\", \"escape\": 0.03866892088939433, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -1.9734, \"times_seen\": 12.0}, {\"site\": 882, \"mutant\": \"D\", \"escape\": -0.03165446363902695, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": 0.3778, \"times_seen\": 18.0}, {\"site\": 882, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 882, \"mutant\": \"K\", \"escape\": -0.010340377348585906, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -2.6946, \"times_seen\": 3.0}, {\"site\": 882, \"mutant\": \"S\", \"escape\": -0.03728389086802438, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -1.3894, \"times_seen\": 10.0}, {\"site\": 882, \"mutant\": \"V\", \"escape\": 0.0030091063013308857, \"epitope\": \"epitope 1\", \"reference_site\": \"885\", \"functional effect\": -1.2089, \"times_seen\": 5.0}, {\"site\": 883, \"mutant\": \"*\", \"escape\": -0.018130027640687194, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -2.5819, \"times_seen\": 6.0}, {\"site\": 883, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 883, \"mutant\": \"C\", \"escape\": -0.047247277110361134, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -0.9062, \"times_seen\": 10.0}, {\"site\": 883, \"mutant\": \"F\", \"escape\": 0.008344173649947542, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": 0.0434, \"times_seen\": 2.0}, {\"site\": 883, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -0.9736, \"times_seen\": null}, {\"site\": 883, \"mutant\": \"L\", \"escape\": -0.2850814744551718, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": 0.0778, \"times_seen\": 29.0}, {\"site\": 883, \"mutant\": \"R\", \"escape\": -0.04317132220131211, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -2.9759, \"times_seen\": 16.0}, {\"site\": 883, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 883, \"mutant\": \"Y\", \"escape\": 0.0009273394776448608, \"epitope\": \"epitope 1\", \"reference_site\": \"886\", \"functional effect\": -0.2983, \"times_seen\": 9.0}, {\"site\": 884, \"mutant\": \"-\", \"escape\": -0.03847638191619421, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 884, \"mutant\": \"A\", \"escape\": -0.010572492083907654, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -1.8786, \"times_seen\": 10.0}, {\"site\": 884, \"mutant\": \"I\", \"escape\": -0.046730092482228376, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.6117, \"times_seen\": 19.0}, {\"site\": 884, \"mutant\": \"L\", \"escape\": 0.008217891494621276, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 884, \"mutant\": \"N\", \"escape\": -1.2545362287952813, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.577, \"times_seen\": 13.0}, {\"site\": 884, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": -2.0907, \"times_seen\": null}, {\"site\": 884, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"887\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"-\", \"escape\": -0.06700947936299874, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": 0.3901, \"times_seen\": 19.0}, {\"site\": 885, \"mutant\": \"A\", \"escape\": -0.0031429721121654848, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -1.1316, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"C\", \"escape\": -0.003410508379930607, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.635, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -2.771, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"G\", \"escape\": -0.0063119496567784275, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.454, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"I\", \"escape\": -0.0014969890070962758, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.1789, \"times_seen\": 31.0}, {\"site\": 885, \"mutant\": \"L\", \"escape\": -0.058253361606149134, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -1.6337, \"times_seen\": 33.0}, {\"site\": 885, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -3.2601, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"S\", \"escape\": -0.0023258202376404877, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -3.006, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -1.3239, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"V\", \"escape\": -0.002481261320712352, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.3042, \"times_seen\": 20.0}, {\"site\": 885, \"mutant\": \"Y\", \"escape\": -0.0072457618293588115, \"epitope\": \"epitope 1\", \"reference_site\": \"888\", \"functional effect\": -0.2256, \"times_seen\": 3.0}, {\"site\": 886, \"mutant\": \"*\", \"escape\": 0.029199938508879166, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.8258, \"times_seen\": 2.0}, {\"site\": 886, \"mutant\": \"-\", \"escape\": -0.03086433282837973, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -1.119, \"times_seen\": 15.0}, {\"site\": 886, \"mutant\": \"E\", \"escape\": 0.0009186596851439872, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.6001, \"times_seen\": 2.0}, {\"site\": 886, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 886, \"mutant\": \"L\", \"escape\": 0.014082109741793806, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -3.051, \"times_seen\": 2.0}, {\"site\": 886, \"mutant\": \"R\", \"escape\": -0.028151283232522924, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.6684, \"times_seen\": 11.0}, {\"site\": 886, \"mutant\": \"S\", \"escape\": -0.05216617650497609, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -0.7051, \"times_seen\": 12.0}, {\"site\": 886, \"mutant\": \"V\", \"escape\": -0.02756782881162852, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -3.131, \"times_seen\": 4.0}, {\"site\": 886, \"mutant\": \"W\", \"escape\": -0.0022484798236166678, \"epitope\": \"epitope 1\", \"reference_site\": \"889\", \"functional effect\": -2.4742, \"times_seen\": 3.0}, {\"site\": 887, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -3.0009, \"times_seen\": null}, {\"site\": 887, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 887, \"mutant\": \"C\", \"escape\": -0.0019043645233203035, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -1.2195, \"times_seen\": 8.0}, {\"site\": 887, \"mutant\": \"E\", \"escape\": 0.00014314381265147555, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -3.2528, \"times_seen\": 1.0}, {\"site\": 887, \"mutant\": \"L\", \"escape\": 0.7951152454236116, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": 0.1666, \"times_seen\": 25.0}, {\"site\": 887, \"mutant\": \"S\", \"escape\": 0.01411055308174952, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -1.1744, \"times_seen\": 31.0}, {\"site\": 887, \"mutant\": \"T\", \"escape\": 0.2379571440173577, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": -0.4164, \"times_seen\": 81.0}, {\"site\": 887, \"mutant\": \"V\", \"escape\": -0.17605212734718215, \"epitope\": \"epitope 1\", \"reference_site\": \"890\", \"functional effect\": 0.4444, \"times_seen\": 109.0}, {\"site\": 888, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.7005, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"D\", \"escape\": 0.013778249958109804, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 888, \"mutant\": \"E\", \"escape\": -0.0020277556553363516, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.9939, \"times_seen\": 3.0}, {\"site\": 888, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.6779, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"M\", \"escape\": -0.00391189609313802, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.7203, \"times_seen\": 1.0}, {\"site\": 888, \"mutant\": \"R\", \"escape\": -0.010822694411162043, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.1703, \"times_seen\": 9.0}, {\"site\": 888, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -2.8072, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"891\", \"functional effect\": -1.7267, \"times_seen\": null}, {\"site\": 889, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 889, \"mutant\": \"C\", \"escape\": -0.002215364107609165, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -1.5322, \"times_seen\": 3.0}, {\"site\": 889, \"mutant\": \"E\", \"escape\": 0.024965227800763677, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -2.5049, \"times_seen\": 2.0}, {\"site\": 889, \"mutant\": \"G\", \"escape\": -0.003822279915093984, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -1.2289, \"times_seen\": 1.0}, {\"site\": 889, \"mutant\": \"P\", \"escape\": 0.04505532121646188, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -2.3039, \"times_seen\": 2.0}, {\"site\": 889, \"mutant\": \"S\", \"escape\": -0.038881429116043344, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -0.3493, \"times_seen\": 27.0}, {\"site\": 889, \"mutant\": \"T\", \"escape\": 0.07304322334981769, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -0.5448, \"times_seen\": 28.0}, {\"site\": 889, \"mutant\": \"V\", \"escape\": 0.22539695693439823, \"epitope\": \"epitope 1\", \"reference_site\": \"892\", \"functional effect\": -0.6734, \"times_seen\": 93.0}, {\"site\": 890, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 890, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -3.0043, \"times_seen\": null}, {\"site\": 890, \"mutant\": \"E\", \"escape\": -3.595717507859589, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.9218, \"times_seen\": 1.0}, {\"site\": 890, \"mutant\": \"L\", \"escape\": -0.09631979556162687, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -0.0444, \"times_seen\": 3.0}, {\"site\": 890, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -0.3442, \"times_seen\": null}, {\"site\": 890, \"mutant\": \"S\", \"escape\": -0.07496349238987764, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.1832, \"times_seen\": 9.0}, {\"site\": 890, \"mutant\": \"T\", \"escape\": -0.03498566320984587, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.3667, \"times_seen\": 7.0}, {\"site\": 890, \"mutant\": \"V\", \"escape\": -0.029001078344345874, \"epitope\": \"epitope 1\", \"reference_site\": \"893\", \"functional effect\": -2.3519, \"times_seen\": 15.0}, {\"site\": 891, \"mutant\": \"F\", \"escape\": -0.01971369939665555, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -0.4678, \"times_seen\": 11.0}, {\"site\": 891, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.0987, \"times_seen\": null}, {\"site\": 891, \"mutant\": \"I\", \"escape\": 0.0011104344094146853, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.6892, \"times_seen\": 9.0}, {\"site\": 891, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 891, \"mutant\": \"P\", \"escape\": 0.016695844772126867, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.8638, \"times_seen\": 3.0}, {\"site\": 891, \"mutant\": \"R\", \"escape\": -0.00384656988240015, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 891, \"mutant\": \"V\", \"escape\": -0.005034953442589642, \"epitope\": \"epitope 1\", \"reference_site\": \"894\", \"functional effect\": -2.0644, \"times_seen\": 2.0}, {\"site\": 892, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.98, \"times_seen\": null}, {\"site\": 892, \"mutant\": \"E\", \"escape\": -0.0039654165451955365, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -1.3112, \"times_seen\": 1.0}, {\"site\": 892, \"mutant\": \"H\", \"escape\": -0.026331349589047672, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -0.7551, \"times_seen\": 18.0}, {\"site\": 892, \"mutant\": \"K\", \"escape\": -0.003315384872406385, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.1146, \"times_seen\": 14.0}, {\"site\": 892, \"mutant\": \"P\", \"escape\": -0.003631216663280296, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.9371, \"times_seen\": 1.0}, {\"site\": 892, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 892, \"mutant\": \"R\", \"escape\": -0.0038654130672974986, \"epitope\": \"epitope 1\", \"reference_site\": \"895\", \"functional effect\": -2.7823, \"times_seen\": 1.0}, {\"site\": 893, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -2.1962, \"times_seen\": null}, {\"site\": 893, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 893, \"mutant\": \"L\", \"escape\": -0.006623282224731205, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -1.1891, \"times_seen\": 2.0}, {\"site\": 893, \"mutant\": \"M\", \"escape\": -0.0042034560088000245, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -1.5844, \"times_seen\": 9.0}, {\"site\": 893, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -3.0026, \"times_seen\": null}, {\"site\": 893, \"mutant\": \"R\", \"escape\": 0.010317008584051787, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -2.6707, \"times_seen\": 3.0}, {\"site\": 893, \"mutant\": \"T\", \"escape\": 0.01789492639234504, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -2.4205, \"times_seen\": 12.0}, {\"site\": 893, \"mutant\": \"V\", \"escape\": 0.00900670610941139, \"epitope\": \"epitope 1\", \"reference_site\": \"896\", \"functional effect\": -1.8276, \"times_seen\": 4.0}, {\"site\": 894, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -3.1269, \"times_seen\": null}, {\"site\": 894, \"mutant\": \"L\", \"escape\": -0.007159611975412003, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.9962, \"times_seen\": 1.0}, {\"site\": 894, \"mutant\": \"M\", \"escape\": -1.0308199769068478, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.696, \"times_seen\": 3.0}, {\"site\": 894, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 894, \"mutant\": \"Q\", \"escape\": -0.013588847699176416, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.8016, \"times_seen\": 2.0}, {\"site\": 894, \"mutant\": \"S\", \"escape\": 0.008723514048922461, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -2.7618, \"times_seen\": 2.0}, {\"site\": 894, \"mutant\": \"T\", \"escape\": 0.00291216411376709, \"epitope\": \"epitope 1\", \"reference_site\": \"897\", \"functional effect\": -3.0526, \"times_seen\": 3.0}, {\"site\": 895, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -2.8593, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -2.4705, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"L\", \"escape\": -0.0028829271974677253, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -2.7561, \"times_seen\": 2.0}, {\"site\": 895, \"mutant\": \"S\", \"escape\": -0.0027723498524331014, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -0.7948, \"times_seen\": 1.0}, {\"site\": 895, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -3.2656, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"898\", \"functional effect\": -1.7283, \"times_seen\": null}, {\"site\": 896, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 896, \"mutant\": \"D\", \"escape\": -0.003262525356605114, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -2.8743, \"times_seen\": 1.0}, {\"site\": 896, \"mutant\": \"L\", \"escape\": 0.020462149224483743, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -1.9038, \"times_seen\": 6.0}, {\"site\": 896, \"mutant\": \"S\", \"escape\": 0.05328391291129368, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -1.4036, \"times_seen\": 14.0}, {\"site\": 896, \"mutant\": \"T\", \"escape\": -0.08814293269428007, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -1.3045, \"times_seen\": 32.0}, {\"site\": 896, \"mutant\": \"V\", \"escape\": -0.003210947723589901, \"epitope\": \"epitope 1\", \"reference_site\": \"899\", \"functional effect\": -0.7626, \"times_seen\": 18.0}, {\"site\": 897, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -0.2541, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"I\", \"escape\": 0.25205998487961406, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -1.8462, \"times_seen\": 31.0}, {\"site\": 897, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -3.114, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"L\", \"escape\": 0.18712279726984862, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -1.6964, \"times_seen\": 5.0}, {\"site\": 897, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -1.9072, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"Q\", \"escape\": 0.013012924350309511, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -2.7554, \"times_seen\": 7.0}, {\"site\": 897, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -2.5266, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"900\", \"functional effect\": -2.9127, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"*\", \"escape\": 0.020580597158772095, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.6303, \"times_seen\": 1.0}, {\"site\": 898, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"H\", \"escape\": -0.02087106534983595, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.9477, \"times_seen\": 4.0}, {\"site\": 898, \"mutant\": \"K\", \"escape\": 0.06400638637655914, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.5577, \"times_seen\": 7.0}, {\"site\": 898, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"R\", \"escape\": 0.0204097461139944, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.8476, \"times_seen\": 1.0}, {\"site\": 898, \"mutant\": \"T\", \"escape\": -0.005736388922701631, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 898, \"mutant\": \"V\", \"escape\": -0.001626244172859768, \"epitope\": \"epitope 1\", \"reference_site\": \"901\", \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 899, \"mutant\": \"I\", \"escape\": -0.005449742734426902, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -2.8048, \"times_seen\": 2.0}, {\"site\": 899, \"mutant\": \"L\", \"escape\": 0.005116026968213976, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -1.6681, \"times_seen\": 7.0}, {\"site\": 899, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 899, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -3.0013, \"times_seen\": null}, {\"site\": 899, \"mutant\": \"V\", \"escape\": 0.008190520099569271, \"epitope\": \"epitope 1\", \"reference_site\": \"902\", \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 900, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"C\", \"escape\": 0.0017527983965440377, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.7687, \"times_seen\": 1.0}, {\"site\": 900, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.9945, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.4536, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"S\", \"escape\": 0.014892029425672058, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.7799, \"times_seen\": 5.0}, {\"site\": 900, \"mutant\": \"T\", \"escape\": -0.002347305742926431, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -2.598, \"times_seen\": 4.0}, {\"site\": 900, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"903\", \"functional effect\": -0.2027, \"times_seen\": null}, {\"site\": 901, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 901, \"mutant\": \"C\", \"escape\": 0.012528379668830967, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -1.5884, \"times_seen\": 3.0}, {\"site\": 901, \"mutant\": \"F\", \"escape\": -0.014624792058558874, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": 0.1966, \"times_seen\": 18.0}, {\"site\": 901, \"mutant\": \"H\", \"escape\": 0.9237809896301278, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -0.7952, \"times_seen\": 21.0}, {\"site\": 901, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": -2.0755, \"times_seen\": null}, {\"site\": 901, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"904\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.8707, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"G\", \"escape\": 0.9241918954405496, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.9103, \"times_seen\": 7.0}, {\"site\": 902, \"mutant\": \"K\", \"escape\": 2.764180178539094, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.5305, \"times_seen\": 5.0}, {\"site\": 902, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.9329, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"S\", \"escape\": 0.104988414609252, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.7124, \"times_seen\": 1.0}, {\"site\": 902, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"905\", \"functional effect\": -2.0613, \"times_seen\": null}, {\"site\": 903, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 903, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -3.0814, \"times_seen\": null}, {\"site\": 903, \"mutant\": \"L\", \"escape\": -0.034991408446395506, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -2.4218, \"times_seen\": 2.0}, {\"site\": 903, \"mutant\": \"S\", \"escape\": 0.01780503524073677, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -1.3472, \"times_seen\": 1.0}, {\"site\": 903, \"mutant\": \"Y\", \"escape\": -0.005177025305056491, \"epitope\": \"epitope 1\", \"reference_site\": \"906\", \"functional effect\": -2.4569, \"times_seen\": 1.0}, {\"site\": 904, \"mutant\": \"D\", \"escape\": 0.0053273174521148575, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -1.1061, \"times_seen\": 7.0}, {\"site\": 904, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -0.115, \"times_seen\": null}, {\"site\": 904, \"mutant\": \"H\", \"escape\": -0.00739161185477978, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -1.3226, \"times_seen\": 6.0}, {\"site\": 904, \"mutant\": \"I\", \"escape\": -0.0035665461100514934, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -2.0818, \"times_seen\": 1.0}, {\"site\": 904, \"mutant\": \"K\", \"escape\": -0.0034779549350256057, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": -2.0047, \"times_seen\": 1.0}, {\"site\": 904, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 904, \"mutant\": \"S\", \"escape\": -0.009907906320637198, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": 0.378, \"times_seen\": 8.0}, {\"site\": 904, \"mutant\": \"T\", \"escape\": -0.020587455727394642, \"epitope\": \"epitope 1\", \"reference_site\": \"907\", \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 905, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -2.5548, \"times_seen\": null}, {\"site\": 905, \"mutant\": \"C\", \"escape\": -0.01573637516695376, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -1.4382, \"times_seen\": 8.0}, {\"site\": 905, \"mutant\": \"D\", \"escape\": -0.012964537711095127, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -2.1475, \"times_seen\": 8.0}, {\"site\": 905, \"mutant\": \"E\", \"escape\": 0.019428579654338033, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -1.2561, \"times_seen\": 1.0}, {\"site\": 905, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 905, \"mutant\": \"S\", \"escape\": 0.021440549540829305, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": 0.2966, \"times_seen\": 6.0}, {\"site\": 905, \"mutant\": \"V\", \"escape\": 0.01154182971390127, \"epitope\": \"epitope 1\", \"reference_site\": \"908\", \"functional effect\": -2.625, \"times_seen\": 2.0}, {\"site\": 906, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 906, \"mutant\": \"L\", \"escape\": 0.015129850663834894, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -2.6475, \"times_seen\": 1.0}, {\"site\": 906, \"mutant\": \"M\", \"escape\": -0.008470345347497826, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -2.758, \"times_seen\": 1.0}, {\"site\": 906, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -2.9022, \"times_seen\": null}, {\"site\": 906, \"mutant\": \"V\", \"escape\": -0.15433880089738042, \"epitope\": \"epitope 1\", \"reference_site\": \"909\", \"functional effect\": -0.2602, \"times_seen\": 39.0}, {\"site\": 907, \"mutant\": \"*\", \"escape\": -0.0032343290769265144, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.9937, \"times_seen\": 1.0}, {\"site\": 907, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -2.9794, \"times_seen\": null}, {\"site\": 907, \"mutant\": \"E\", \"escape\": -0.01080127819776171, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.4367, \"times_seen\": 20.0}, {\"site\": 907, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 907, \"mutant\": \"R\", \"escape\": 0.027382344025638338, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.4034, \"times_seen\": 2.0}, {\"site\": 907, \"mutant\": \"V\", \"escape\": -0.003261314645254353, \"epitope\": \"epitope 1\", \"reference_site\": \"910\", \"functional effect\": -1.2281, \"times_seen\": 1.0}, {\"site\": 908, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -2.9987, \"times_seen\": null}, {\"site\": 908, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -1.1709, \"times_seen\": null}, {\"site\": 908, \"mutant\": \"I\", \"escape\": 1.8327260115260104, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -0.9528, \"times_seen\": 13.0}, {\"site\": 908, \"mutant\": \"L\", \"escape\": 0.017276088000638463, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -1.7645, \"times_seen\": 10.0}, {\"site\": 908, \"mutant\": \"M\", \"escape\": 0.07119613536357394, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": -2.6745, \"times_seen\": 1.0}, {\"site\": 908, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"911\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 909, \"mutant\": \"A\", \"escape\": 0.03424495235339363, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -1.8363, \"times_seen\": 18.0}, {\"site\": 909, \"mutant\": \"I\", \"escape\": -0.01028585517682158, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -2.7658, \"times_seen\": 5.0}, {\"site\": 909, \"mutant\": \"L\", \"escape\": -1.21080137801436, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -1.7886, \"times_seen\": 3.0}, {\"site\": 909, \"mutant\": \"N\", \"escape\": -0.023219030166721603, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": -2.2041, \"times_seen\": 4.0}, {\"site\": 909, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"912\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.375, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"E\", \"escape\": 0.05866221547912137, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -0.0022, \"times_seen\": 13.0}, {\"site\": 910, \"mutant\": \"H\", \"escape\": -0.008292092061827372, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.2618, \"times_seen\": 3.0}, {\"site\": 910, \"mutant\": \"K\", \"escape\": 0.03052452783856613, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.4255, \"times_seen\": 3.0}, {\"site\": 910, \"mutant\": \"L\", \"escape\": -0.0033026773632152014, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.311, \"times_seen\": 10.0}, {\"site\": 910, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -3.1312, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"R\", \"escape\": -0.014767302393847215, \"epitope\": \"epitope 1\", \"reference_site\": \"913\", \"functional effect\": -2.3632, \"times_seen\": 3.0}, {\"site\": 911, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -1.9481, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"D\", \"escape\": 0.01871265696858971, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -2.6387, \"times_seen\": 2.0}, {\"site\": 911, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -1.2052, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"S\", \"escape\": -0.008022330534719874, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -1.9719, \"times_seen\": 5.0}, {\"site\": 911, \"mutant\": \"Y\", \"escape\": -0.006358089810756421, \"epitope\": \"epitope 1\", \"reference_site\": \"914\", \"functional effect\": -2.6153, \"times_seen\": 2.0}, {\"site\": 912, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -3.1761, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -1.4918, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.9571, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"I\", \"escape\": -0.0025642205979689997, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -0.4727, \"times_seen\": 26.0}, {\"site\": 912, \"mutant\": \"L\", \"escape\": -0.000628043753318962, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.1996, \"times_seen\": 1.0}, {\"site\": 912, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.8687, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"S\", \"escape\": -0.01166084028783239, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": -2.468, \"times_seen\": 2.0}, {\"site\": 912, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"915\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"F\", \"escape\": -0.026440767323105203, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -1.7646, \"times_seen\": 29.0}, {\"site\": 913, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -2.3525, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -2.9718, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"916\", \"functional effect\": -3.0003, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -1.2773, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.9051, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"F\", \"escape\": -0.04174661228053278, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -0.1498, \"times_seen\": 7.0}, {\"site\": 914, \"mutant\": \"H\", \"escape\": -0.02060848713232158, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.4585, \"times_seen\": 3.0}, {\"site\": 914, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -3.2613, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"917\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 915, \"mutant\": \"*\", \"escape\": -0.0005431197278140519, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.393, \"times_seen\": 2.0}, {\"site\": 915, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 915, \"mutant\": \"A\", \"escape\": 0.036819222742066796, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -0.5814, \"times_seen\": 4.0}, {\"site\": 915, \"mutant\": \"D\", \"escape\": -0.0005778024112458271, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.073, \"times_seen\": 7.0}, {\"site\": 915, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 915, \"mutant\": \"G\", \"escape\": 0.03927499536722676, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -1.6992, \"times_seen\": 10.0}, {\"site\": 915, \"mutant\": \"K\", \"escape\": 0.093538723355189, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -1.4865, \"times_seen\": 29.0}, {\"site\": 915, \"mutant\": \"Q\", \"escape\": 0.049210804252774486, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": 0.4295, \"times_seen\": 5.0}, {\"site\": 915, \"mutant\": \"T\", \"escape\": 0.00047380269398179705, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -1.0897, \"times_seen\": 1.0}, {\"site\": 915, \"mutant\": \"V\", \"escape\": -0.009313990468603081, \"epitope\": \"epitope 1\", \"reference_site\": \"918\", \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 916, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.0581, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.9814, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"S\", \"escape\": -0.001243219222984471, \"epitope\": \"epitope 1\", \"reference_site\": \"919\", \"functional effect\": -2.0356, \"times_seen\": 1.0}, {\"site\": 917, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.9981, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -1.4999, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"K\", \"escape\": -0.018750921391860017, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.9199, \"times_seen\": 4.0}, {\"site\": 917, \"mutant\": \"L\", \"escape\": -0.9526179197168344, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -1.2457, \"times_seen\": 23.0}, {\"site\": 917, \"mutant\": \"P\", \"escape\": -0.009613636170198123, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -3.1032, \"times_seen\": 1.0}, {\"site\": 917, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"R\", \"escape\": -0.009915192123264043, \"epitope\": \"epitope 1\", \"reference_site\": \"920\", \"functional effect\": -2.7045, \"times_seen\": 1.0}, {\"site\": 918, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 918, \"mutant\": \"E\", \"escape\": -0.03188930072581934, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.1925, \"times_seen\": 9.0}, {\"site\": 918, \"mutant\": \"I\", \"escape\": 0.024809335715141236, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.25, \"times_seen\": 11.0}, {\"site\": 918, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 918, \"mutant\": \"N\", \"escape\": 0.03663132781750899, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": -0.1995, \"times_seen\": 11.0}, {\"site\": 918, \"mutant\": \"R\", \"escape\": -0.048438995031841896, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": 0.2591, \"times_seen\": 8.0}, {\"site\": 918, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"921\", \"functional effect\": -2.9992, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"F\", \"escape\": -0.026175914228521786, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -0.1284, \"times_seen\": 18.0}, {\"site\": 919, \"mutant\": \"I\", \"escape\": -0.02713567790654762, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -1.1435, \"times_seen\": 5.0}, {\"site\": 919, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"M\", \"escape\": -0.02266677313733253, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.2593, \"times_seen\": 20.0}, {\"site\": 919, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"S\", \"escape\": -0.8618032152920249, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": 0.3547, \"times_seen\": 13.0}, {\"site\": 919, \"mutant\": \"V\", \"escape\": 0.19593978498860343, \"epitope\": \"epitope 1\", \"reference_site\": \"922\", \"functional effect\": -0.7893, \"times_seen\": 14.0}, {\"site\": 920, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -3.0157, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"L\", \"escape\": -0.007025268570419318, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -2.1225, \"times_seen\": 3.0}, {\"site\": 920, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -1.6968, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": -3.0143, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"V\", \"escape\": 0.00347260636364668, \"epitope\": \"epitope 1\", \"reference_site\": \"923\", \"functional effect\": 0.3428, \"times_seen\": 8.0}, {\"site\": 921, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 921, \"mutant\": \"C\", \"escape\": -0.030079506445904795, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -1.8836, \"times_seen\": 5.0}, {\"site\": 921, \"mutant\": \"D\", \"escape\": -0.02236626673780384, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -1.6701, \"times_seen\": 1.0}, {\"site\": 921, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 921, \"mutant\": \"P\", \"escape\": -0.020509292384009184, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 921, \"mutant\": \"S\", \"escape\": -0.01874596814947127, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -0.5601, \"times_seen\": 19.0}, {\"site\": 921, \"mutant\": \"T\", \"escape\": -0.5145733821167615, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -2.3407, \"times_seen\": 18.0}, {\"site\": 921, \"mutant\": \"V\", \"escape\": -2.9892895329042366, \"epitope\": \"epitope 1\", \"reference_site\": \"924\", \"functional effect\": -2.117, \"times_seen\": 23.0}, {\"site\": 922, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 922, \"mutant\": \"A\", \"escape\": 6.222080241553245e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.5035, \"times_seen\": 7.0}, {\"site\": 922, \"mutant\": \"D\", \"escape\": -0.007218481074172571, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.1584, \"times_seen\": 20.0}, {\"site\": 922, \"mutant\": \"I\", \"escape\": 0.07958309520036527, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -1.4171, \"times_seen\": 10.0}, {\"site\": 922, \"mutant\": \"K\", \"escape\": -0.015674531177779383, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.7135, \"times_seen\": 14.0}, {\"site\": 922, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 922, \"mutant\": \"Q\", \"escape\": 0.007132398038708949, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.7559, \"times_seen\": 5.0}, {\"site\": 922, \"mutant\": \"S\", \"escape\": 0.024208795687409204, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.5794, \"times_seen\": 11.0}, {\"site\": 922, \"mutant\": \"T\", \"escape\": 0.037112920971842406, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.8221, \"times_seen\": 10.0}, {\"site\": 922, \"mutant\": \"Y\", \"escape\": -0.8683256586763308, \"epitope\": \"epitope 1\", \"reference_site\": \"925\", \"functional effect\": -0.2915, \"times_seen\": 20.0}, {\"site\": 923, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.7711, \"times_seen\": null}, {\"site\": 923, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 923, \"mutant\": \"H\", \"escape\": -0.018818342117096477, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -1.3777, \"times_seen\": 6.0}, {\"site\": 923, \"mutant\": \"K\", \"escape\": -0.003928587606829311, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -1.2896, \"times_seen\": 15.0}, {\"site\": 923, \"mutant\": \"L\", \"escape\": -0.05219990106668601, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -0.1869, \"times_seen\": 16.0}, {\"site\": 923, \"mutant\": \"N\", \"escape\": 0.007816149144484396, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.9703, \"times_seen\": 3.0}, {\"site\": 923, \"mutant\": \"P\", \"escape\": -0.0037893114960032884, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.9053, \"times_seen\": 1.0}, {\"site\": 923, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 923, \"mutant\": \"R\", \"escape\": 0.00966113036951102, \"epitope\": \"epitope 1\", \"reference_site\": \"926\", \"functional effect\": -2.3285, \"times_seen\": 8.0}, {\"site\": 924, \"mutant\": \"-\", \"escape\": -0.0060425850601345255, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 924, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 924, \"mutant\": \"I\", \"escape\": -0.010055601844837237, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -2.2115, \"times_seen\": 4.0}, {\"site\": 924, \"mutant\": \"L\", \"escape\": -0.01720212115617323, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -2.0167, \"times_seen\": 5.0}, {\"site\": 924, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -1.6718, \"times_seen\": null}, {\"site\": 924, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -1.4792, \"times_seen\": null}, {\"site\": 924, \"mutant\": \"Y\", \"escape\": 0.006337412168931735, \"epitope\": \"epitope 1\", \"reference_site\": \"927\", \"functional effect\": -2.7049, \"times_seen\": 1.0}, {\"site\": 925, \"mutant\": \"-\", \"escape\": -0.005640159852007018, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 925, \"mutant\": \"D\", \"escape\": 0.019463522504726397, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.5455, \"times_seen\": 2.0}, {\"site\": 925, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 925, \"mutant\": \"I\", \"escape\": -0.003259522922616279, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.717, \"times_seen\": 1.0}, {\"site\": 925, \"mutant\": \"K\", \"escape\": -0.004635631790694883, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.2128, \"times_seen\": 3.0}, {\"site\": 925, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 925, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 925, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"928\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 926, \"mutant\": \"-\", \"escape\": -0.006619013096820215, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 926, \"mutant\": \"A\", \"escape\": -0.004202563227578496, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.2868, \"times_seen\": 1.0}, {\"site\": 926, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -2.9792, \"times_seen\": null}, {\"site\": 926, \"mutant\": \"F\", \"escape\": 0.2302918488241373, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.488, \"times_seen\": 3.0}, {\"site\": 926, \"mutant\": \"G\", \"escape\": 0.017952191649969293, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.2219, \"times_seen\": 4.0}, {\"site\": 926, \"mutant\": \"I\", \"escape\": 0.2979913425103597, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.0993, \"times_seen\": 28.0}, {\"site\": 926, \"mutant\": \"N\", \"escape\": -0.8264664073903016, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.1288, \"times_seen\": 20.0}, {\"site\": 926, \"mutant\": \"P\", \"escape\": 0.01705394197475843, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -2.9645, \"times_seen\": 1.0}, {\"site\": 926, \"mutant\": \"R\", \"escape\": -0.01276120339577341, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.2751, \"times_seen\": 7.0}, {\"site\": 926, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 926, \"mutant\": \"T\", \"escape\": -0.010313275339968182, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": 0.1001, \"times_seen\": 30.0}, {\"site\": 926, \"mutant\": \"V\", \"escape\": -0.08679393389100976, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.4408, \"times_seen\": 14.0}, {\"site\": 926, \"mutant\": \"Y\", \"escape\": 0.01920914760298165, \"epitope\": \"epitope 1\", \"reference_site\": \"929\", \"functional effect\": -0.4279, \"times_seen\": 8.0}, {\"site\": 927, \"mutant\": \"-\", \"escape\": -0.006123589003873556, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 927, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 927, \"mutant\": \"C\", \"escape\": -0.0074890995051548215, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.7905, \"times_seen\": 4.0}, {\"site\": 927, \"mutant\": \"D\", \"escape\": -0.0026094936826870974, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -2.3045, \"times_seen\": 1.0}, {\"site\": 927, \"mutant\": \"H\", \"escape\": -0.00927344064169385, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.575, \"times_seen\": 11.0}, {\"site\": 927, \"mutant\": \"L\", \"escape\": -0.007624732890877297, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -1.8084, \"times_seen\": 3.0}, {\"site\": 927, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 927, \"mutant\": \"R\", \"escape\": -0.024933334699504758, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -0.4934, \"times_seen\": 7.0}, {\"site\": 927, \"mutant\": \"S\", \"escape\": -0.0017756995902116404, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -2.9182, \"times_seen\": 1.0}, {\"site\": 927, \"mutant\": \"T\", \"escape\": -0.02500713284115302, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -1.9236, \"times_seen\": 4.0}, {\"site\": 927, \"mutant\": \"V\", \"escape\": -0.00950159590113266, \"epitope\": \"epitope 1\", \"reference_site\": \"930\", \"functional effect\": -2.7247, \"times_seen\": 3.0}, {\"site\": 928, \"mutant\": \"-\", \"escape\": -0.006130952411280946, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 928, \"mutant\": \"F\", \"escape\": -0.010297534418740218, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.4695, \"times_seen\": 2.0}, {\"site\": 928, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 928, \"mutant\": \"L\", \"escape\": 0.0005070956218222516, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 928, \"mutant\": \"M\", \"escape\": -0.015478184583622857, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.3694, \"times_seen\": 5.0}, {\"site\": 928, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -3.0956, \"times_seen\": null}, {\"site\": 928, \"mutant\": \"T\", \"escape\": -0.003797779603915208, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -2.4165, \"times_seen\": 1.0}, {\"site\": 928, \"mutant\": \"V\", \"escape\": -0.021795310481280583, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -0.6782, \"times_seen\": 8.0}, {\"site\": 928, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"931\", \"functional effect\": -2.9437, \"times_seen\": null}, {\"site\": 929, \"mutant\": \"-\", \"escape\": -0.005959329973010408, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 929, \"mutant\": \"A\", \"escape\": -0.003081611288804812, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.1662, \"times_seen\": 7.0}, {\"site\": 929, \"mutant\": \"C\", \"escape\": 0.007804049479953162, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.0122, \"times_seen\": 14.0}, {\"site\": 929, \"mutant\": \"D\", \"escape\": 0.017156042714300518, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.3633, \"times_seen\": 79.0}, {\"site\": 929, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 929, \"mutant\": \"L\", \"escape\": -0.0022082851283744052, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.1018, \"times_seen\": 8.0}, {\"site\": 929, \"mutant\": \"N\", \"escape\": -0.003293979115186326, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 929, \"mutant\": \"R\", \"escape\": -0.0031415090442704933, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.0408, \"times_seen\": 26.0}, {\"site\": 929, \"mutant\": \"S\", \"escape\": 0.05945555055215185, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": -0.1759, \"times_seen\": 41.0}, {\"site\": 929, \"mutant\": \"T\", \"escape\": -0.28876706198721347, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.2646, \"times_seen\": 18.0}, {\"site\": 929, \"mutant\": \"V\", \"escape\": -0.00013389319430477553, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.1853, \"times_seen\": 27.0}, {\"site\": 929, \"mutant\": \"W\", \"escape\": 0.07203817005190405, \"epitope\": \"epitope 1\", \"reference_site\": \"932\", \"functional effect\": 0.2353, \"times_seen\": 15.0}, {\"site\": 930, \"mutant\": \"-\", \"escape\": -0.00573134128599732, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 930, \"mutant\": \"E\", \"escape\": 0.051061561743205135, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.2416, \"times_seen\": 21.0}, {\"site\": 930, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -2.0862, \"times_seen\": null}, {\"site\": 930, \"mutant\": \"H\", \"escape\": -0.0029712903040820244, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.2802, \"times_seen\": 2.0}, {\"site\": 930, \"mutant\": \"I\", \"escape\": 0.0004327391246384072, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -0.2066, \"times_seen\": 4.0}, {\"site\": 930, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 930, \"mutant\": \"N\", \"escape\": -0.0056438597959650675, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.3491, \"times_seen\": 11.0}, {\"site\": 930, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": -3.3409, \"times_seen\": null}, {\"site\": 930, \"mutant\": \"Q\", \"escape\": -0.03993613527887367, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.0968, \"times_seen\": 16.0}, {\"site\": 930, \"mutant\": \"R\", \"escape\": -0.0193104637784281, \"epitope\": \"epitope 1\", \"reference_site\": \"933\", \"functional effect\": 0.2991, \"times_seen\": 11.0}, {\"site\": 931, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 931, \"mutant\": \"F\", \"escape\": 0.0042398401095382204, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -0.1736, \"times_seen\": 6.0}, {\"site\": 931, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 931, \"mutant\": \"L\", \"escape\": 0.01843458746360566, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.1345, \"times_seen\": 9.0}, {\"site\": 931, \"mutant\": \"M\", \"escape\": 0.005759370939601952, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -0.5846, \"times_seen\": 24.0}, {\"site\": 931, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -2.5924, \"times_seen\": null}, {\"site\": 931, \"mutant\": \"Q\", \"escape\": -0.003378375493969255, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": -1.3962, \"times_seen\": 8.0}, {\"site\": 931, \"mutant\": \"T\", \"escape\": -0.015917124027437224, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.0468, \"times_seen\": 8.0}, {\"site\": 931, \"mutant\": \"V\", \"escape\": -0.014707424077590566, \"epitope\": \"epitope 1\", \"reference_site\": \"934\", \"functional effect\": 0.1355, \"times_seen\": 22.0}, {\"site\": 932, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -2.4683, \"times_seen\": null}, {\"site\": 932, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 932, \"mutant\": \"E\", \"escape\": 0.008923158556751121, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.131, \"times_seen\": 8.0}, {\"site\": 932, \"mutant\": \"H\", \"escape\": -0.02609217290752725, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.3085, \"times_seen\": 33.0}, {\"site\": 932, \"mutant\": \"K\", \"escape\": 0.7936543639964098, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.1257, \"times_seen\": 32.0}, {\"site\": 932, \"mutant\": \"L\", \"escape\": -0.023840090015743907, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.6738, \"times_seen\": 12.0}, {\"site\": 932, \"mutant\": \"P\", \"escape\": 0.018605380439108105, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.1322, \"times_seen\": 2.0}, {\"site\": 932, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 932, \"mutant\": \"R\", \"escape\": -0.05065958674873718, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": -0.061, \"times_seen\": 66.0}, {\"site\": 932, \"mutant\": \"S\", \"escape\": -0.008328937814771275, \"epitope\": \"epitope 1\", \"reference_site\": \"935\", \"functional effect\": 0.1988, \"times_seen\": 9.0}, {\"site\": 933, \"mutant\": \"*\", \"escape\": -0.0004727292475530357, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 933, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 933, \"mutant\": \"A\", \"escape\": -0.16800723872210935, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1452, \"times_seen\": 116.0}, {\"site\": 933, \"mutant\": \"C\", \"escape\": -2.044043205978694, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.341, \"times_seen\": 33.0}, {\"site\": 933, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 933, \"mutant\": \"E\", \"escape\": 0.06439314629237991, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0714, \"times_seen\": 117.0}, {\"site\": 933, \"mutant\": \"F\", \"escape\": -0.0222616999644078, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.3468, \"times_seen\": 31.0}, {\"site\": 933, \"mutant\": \"G\", \"escape\": -0.025884471668698675, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.6219, \"times_seen\": 142.0}, {\"site\": 933, \"mutant\": \"H\", \"escape\": -0.0718766073455552, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.01, \"times_seen\": 58.0}, {\"site\": 933, \"mutant\": \"I\", \"escape\": 0.005141860204274028, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0112, \"times_seen\": 26.0}, {\"site\": 933, \"mutant\": \"K\", \"escape\": -0.42075175034661766, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1797, \"times_seen\": 42.0}, {\"site\": 933, \"mutant\": \"L\", \"escape\": -0.15201662669038274, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0491, \"times_seen\": 98.0}, {\"site\": 933, \"mutant\": \"M\", \"escape\": 0.6465154347520743, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.1434, \"times_seen\": 45.0}, {\"site\": 933, \"mutant\": \"N\", \"escape\": -0.055500224662217046, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1217, \"times_seen\": 91.0}, {\"site\": 933, \"mutant\": \"P\", \"escape\": -0.006102113908732075, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -1.156, \"times_seen\": 43.0}, {\"site\": 933, \"mutant\": \"Q\", \"escape\": 0.08095774475982599, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.0172, \"times_seen\": 49.0}, {\"site\": 933, \"mutant\": \"R\", \"escape\": -0.378306393475287, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0486, \"times_seen\": 120.0}, {\"site\": 933, \"mutant\": \"S\", \"escape\": -0.4234746097336998, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1925, \"times_seen\": 109.0}, {\"site\": 933, \"mutant\": \"T\", \"escape\": -2.2792358660249157, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": 0.0011, \"times_seen\": 93.0}, {\"site\": 933, \"mutant\": \"V\", \"escape\": 0.2094836242279918, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.0316, \"times_seen\": 120.0}, {\"site\": 933, \"mutant\": \"W\", \"escape\": -0.06917001140865502, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.2886, \"times_seen\": 56.0}, {\"site\": 933, \"mutant\": \"Y\", \"escape\": 0.049536097249952685, \"epitope\": \"epitope 1\", \"reference_site\": \"936\", \"functional effect\": -0.1037, \"times_seen\": 108.0}, {\"site\": 934, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"A\", \"escape\": -0.01220014129170125, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.3931, \"times_seen\": 11.0}, {\"site\": 934, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.3044, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"F\", \"escape\": -0.0024696471661541947, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.2537, \"times_seen\": 3.0}, {\"site\": 934, \"mutant\": \"H\", \"escape\": -0.013618600907845418, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.1902, \"times_seen\": 13.0}, {\"site\": 934, \"mutant\": \"L\", \"escape\": -0.007206862748696789, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -0.0403, \"times_seen\": 3.0}, {\"site\": 934, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.6679, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": -1.7045, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"T\", \"escape\": -0.0023449756928478724, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.3646, \"times_seen\": 19.0}, {\"site\": 934, \"mutant\": \"Y\", \"escape\": -0.012765893224556221, \"epitope\": \"epitope 1\", \"reference_site\": \"937\", \"functional effect\": 0.085, \"times_seen\": 4.0}, {\"site\": 935, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"F\", \"escape\": 0.006392880040720884, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -0.2643, \"times_seen\": 16.0}, {\"site\": 935, \"mutant\": \"I\", \"escape\": -0.019830475250522783, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -0.4609, \"times_seen\": 19.0}, {\"site\": 935, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"M\", \"escape\": -0.3696192709433497, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -0.4381, \"times_seen\": 7.0}, {\"site\": 935, \"mutant\": \"P\", \"escape\": -0.07019221574156366, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -2.0938, \"times_seen\": 1.0}, {\"site\": 935, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"T\", \"escape\": -0.0056292925933950355, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -2.6479, \"times_seen\": 1.0}, {\"site\": 935, \"mutant\": \"V\", \"escape\": -0.0042827467967553046, \"epitope\": \"epitope 1\", \"reference_site\": \"938\", \"functional effect\": -1.144, \"times_seen\": 6.0}, {\"site\": 936, \"mutant\": \"*\", \"escape\": 2.3694021869070294, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -2.8311, \"times_seen\": 10.0}, {\"site\": 936, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 936, \"mutant\": \"A\", \"escape\": -0.06748648750692632, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.1087, \"times_seen\": 165.0}, {\"site\": 936, \"mutant\": \"C\", \"escape\": 0.053188668363868104, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.6542, \"times_seen\": 61.0}, {\"site\": 936, \"mutant\": \"D\", \"escape\": 0.04611531575620373, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.4094, \"times_seen\": 72.0}, {\"site\": 936, \"mutant\": \"E\", \"escape\": -0.060896786918378486, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.0374, \"times_seen\": 62.0}, {\"site\": 936, \"mutant\": \"F\", \"escape\": -0.02033047435701441, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.7198, \"times_seen\": 99.0}, {\"site\": 936, \"mutant\": \"G\", \"escape\": -0.17350810664616648, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.0382, \"times_seen\": 62.0}, {\"site\": 936, \"mutant\": \"H\", \"escape\": -0.04023671649629663, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.4664, \"times_seen\": 49.0}, {\"site\": 936, \"mutant\": \"I\", \"escape\": -0.9169732865164429, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.3065, \"times_seen\": 47.0}, {\"site\": 936, \"mutant\": \"K\", \"escape\": 0.01478922243018533, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.2325, \"times_seen\": 27.0}, {\"site\": 936, \"mutant\": \"L\", \"escape\": 0.17433230218855308, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.6924, \"times_seen\": 140.0}, {\"site\": 936, \"mutant\": \"M\", \"escape\": -0.0313699607803556, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.2322, \"times_seen\": 26.0}, {\"site\": 936, \"mutant\": \"N\", \"escape\": 0.08368331595601439, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.309, \"times_seen\": 69.0}, {\"site\": 936, \"mutant\": \"P\", \"escape\": -0.010950753615387474, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.9366, \"times_seen\": 51.0}, {\"site\": 936, \"mutant\": \"Q\", \"escape\": 0.00708092902729073, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.0502, \"times_seen\": 36.0}, {\"site\": 936, \"mutant\": \"R\", \"escape\": -0.2200520093191773, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.2679, \"times_seen\": 76.0}, {\"site\": 936, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 936, \"mutant\": \"T\", \"escape\": -0.05328348297022413, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.5069, \"times_seen\": 140.0}, {\"site\": 936, \"mutant\": \"V\", \"escape\": 0.029698934605940693, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.5598, \"times_seen\": 83.0}, {\"site\": 936, \"mutant\": \"W\", \"escape\": 0.03383609733655988, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -1.3738, \"times_seen\": 21.0}, {\"site\": 936, \"mutant\": \"Y\", \"escape\": -1.384286523842314, \"epitope\": \"epitope 1\", \"reference_site\": \"939\", \"functional effect\": -0.7689, \"times_seen\": 137.0}, {\"site\": 937, \"mutant\": \"A\", \"escape\": 0.02540755084096684, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.3529, \"times_seen\": 33.0}, {\"site\": 937, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -1.6109, \"times_seen\": null}, {\"site\": 937, \"mutant\": \"F\", \"escape\": 0.02367607397755566, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.5469, \"times_seen\": 40.0}, {\"site\": 937, \"mutant\": \"G\", \"escape\": -0.008281874726806054, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.1498, \"times_seen\": 9.0}, {\"site\": 937, \"mutant\": \"I\", \"escape\": 0.011537452026724439, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.7398, \"times_seen\": 4.0}, {\"site\": 937, \"mutant\": \"N\", \"escape\": -0.09554155173364604, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.0335, \"times_seen\": 57.0}, {\"site\": 937, \"mutant\": \"P\", \"escape\": -0.03098176818160808, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": 0.0747, \"times_seen\": 21.0}, {\"site\": 937, \"mutant\": \"R\", \"escape\": -0.015177691894780451, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.1382, \"times_seen\": 7.0}, {\"site\": 937, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 937, \"mutant\": \"T\", \"escape\": -0.008183276717891942, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": 0.0508, \"times_seen\": 32.0}, {\"site\": 937, \"mutant\": \"Y\", \"escape\": -0.008609369594376644, \"epitope\": \"epitope 1\", \"reference_site\": \"940\", \"functional effect\": -0.64, \"times_seen\": 20.0}, {\"site\": 938, \"mutant\": \"A\", \"escape\": -0.03673775557166859, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -0.4902, \"times_seen\": 24.0}, {\"site\": 938, \"mutant\": \"C\", \"escape\": -0.0024484933371084674, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -0.3262, \"times_seen\": 14.0}, {\"site\": 938, \"mutant\": \"F\", \"escape\": 1.047944387916744, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -1.7567, \"times_seen\": 19.0}, {\"site\": 938, \"mutant\": \"I\", \"escape\": -0.0075371856121744935, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": -2.3738, \"times_seen\": 20.0}, {\"site\": 938, \"mutant\": \"K\", \"escape\": -0.09535407681963107, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.0207, \"times_seen\": 41.0}, {\"site\": 938, \"mutant\": \"P\", \"escape\": -0.037348762960918686, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.1825, \"times_seen\": 21.0}, {\"site\": 938, \"mutant\": \"S\", \"escape\": -0.06593536910506005, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.2632, \"times_seen\": 63.0}, {\"site\": 938, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"941\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 939, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 939, \"mutant\": \"D\", \"escape\": -0.8437587399513241, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 939, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": -0.4675, \"times_seen\": null}, {\"site\": 939, \"mutant\": \"K\", \"escape\": 0.0076275146224921864, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.3737, \"times_seen\": 9.0}, {\"site\": 939, \"mutant\": \"S\", \"escape\": -0.04663413576526517, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": -0.0503, \"times_seen\": 23.0}, {\"site\": 939, \"mutant\": \"T\", \"escape\": -0.06676864577602933, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.1371, \"times_seen\": 73.0}, {\"site\": 939, \"mutant\": \"V\", \"escape\": -0.03142309544010214, \"epitope\": \"epitope 1\", \"reference_site\": \"942\", \"functional effect\": 0.0072, \"times_seen\": 28.0}, {\"site\": 940, \"mutant\": \"*\", \"escape\": -0.023848654113464596, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -2.1849, \"times_seen\": 4.0}, {\"site\": 940, \"mutant\": \"A\", \"escape\": -0.5738820087204439, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.1717, \"times_seen\": 54.0}, {\"site\": 940, \"mutant\": \"C\", \"escape\": -0.1294490157674453, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0675, \"times_seen\": 45.0}, {\"site\": 940, \"mutant\": \"D\", \"escape\": -0.36869078214256595, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.3598, \"times_seen\": 41.0}, {\"site\": 940, \"mutant\": \"E\", \"escape\": -0.026612822885089763, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0001, \"times_seen\": 11.0}, {\"site\": 940, \"mutant\": \"F\", \"escape\": -0.08585131558168077, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.2112, \"times_seen\": 46.0}, {\"site\": 940, \"mutant\": \"G\", \"escape\": 0.2884551944957437, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1457, \"times_seen\": 72.0}, {\"site\": 940, \"mutant\": \"H\", \"escape\": -0.007721006006927713, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0644, \"times_seen\": 24.0}, {\"site\": 940, \"mutant\": \"I\", \"escape\": 0.022459830178217777, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.2432, \"times_seen\": 31.0}, {\"site\": 940, \"mutant\": \"K\", \"escape\": 0.07388041212695562, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.2043, \"times_seen\": 20.0}, {\"site\": 940, \"mutant\": \"L\", \"escape\": -0.06523198519111531, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.1505, \"times_seen\": 68.0}, {\"site\": 940, \"mutant\": \"M\", \"escape\": -0.011862491811467507, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1411, \"times_seen\": 28.0}, {\"site\": 940, \"mutant\": \"N\", \"escape\": 0.03297670855963445, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.3343, \"times_seen\": 42.0}, {\"site\": 940, \"mutant\": \"P\", \"escape\": -0.07753955254605477, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.4107, \"times_seen\": 73.0}, {\"site\": 940, \"mutant\": \"Q\", \"escape\": -0.0030594208324240713, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1028, \"times_seen\": 3.0}, {\"site\": 940, \"mutant\": \"R\", \"escape\": -0.04413305478218617, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.2136, \"times_seen\": 59.0}, {\"site\": 940, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 940, \"mutant\": \"T\", \"escape\": 0.054784034585938335, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.1314, \"times_seen\": 36.0}, {\"site\": 940, \"mutant\": \"V\", \"escape\": -0.16261041116324695, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": -0.2812, \"times_seen\": 64.0}, {\"site\": 940, \"mutant\": \"W\", \"escape\": 0.004634331467909888, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.363, \"times_seen\": 7.0}, {\"site\": 940, \"mutant\": \"Y\", \"escape\": 0.08373872795645362, \"epitope\": \"epitope 1\", \"reference_site\": \"943\", \"functional effect\": 0.2419, \"times_seen\": 46.0}, {\"site\": 941, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 941, \"mutant\": \"C\", \"escape\": -0.008703456245540375, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -0.1909, \"times_seen\": 6.0}, {\"site\": 941, \"mutant\": \"D\", \"escape\": 0.008419200032927758, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -1.4308, \"times_seen\": 5.0}, {\"site\": 941, \"mutant\": \"P\", \"escape\": -0.005762892895000629, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 941, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -0.1028, \"times_seen\": null}, {\"site\": 941, \"mutant\": \"S\", \"escape\": 0.01544478117187118, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.3315, \"times_seen\": 20.0}, {\"site\": 941, \"mutant\": \"T\", \"escape\": -0.047207046364291766, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.25, \"times_seen\": 24.0}, {\"site\": 941, \"mutant\": \"V\", \"escape\": -0.10341406792248792, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": 0.1042, \"times_seen\": 23.0}, {\"site\": 941, \"mutant\": \"W\", \"escape\": 0.022414977225000018, \"epitope\": \"epitope 1\", \"reference_site\": \"944\", \"functional effect\": -0.2985, \"times_seen\": 1.0}, {\"site\": 942, \"mutant\": \"C\", \"escape\": 0.011391432360055673, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.2514, \"times_seen\": 9.0}, {\"site\": 942, \"mutant\": \"F\", \"escape\": 0.020006490309221702, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -1.0993, \"times_seen\": 8.0}, {\"site\": 942, \"mutant\": \"I\", \"escape\": 0.0014060138261426834, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.5101, \"times_seen\": 4.0}, {\"site\": 942, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 942, \"mutant\": \"M\", \"escape\": 0.02664740023950081, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.0568, \"times_seen\": 4.0}, {\"site\": 942, \"mutant\": \"P\", \"escape\": 0.019350734315725673, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -2.7921, \"times_seen\": 17.0}, {\"site\": 942, \"mutant\": \"Q\", \"escape\": -0.0031040521739935816, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -1.8188, \"times_seen\": 1.0}, {\"site\": 942, \"mutant\": \"R\", \"escape\": -0.00012861692762108413, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -2.9466, \"times_seen\": 1.0}, {\"site\": 942, \"mutant\": \"S\", \"escape\": -0.009486425725906585, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -1.3313, \"times_seen\": 11.0}, {\"site\": 942, \"mutant\": \"T\", \"escape\": -0.0015289400650794868, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.1611, \"times_seen\": 6.0}, {\"site\": 942, \"mutant\": \"V\", \"escape\": -0.0008505283072481982, \"epitope\": \"epitope 1\", \"reference_site\": \"945\", \"functional effect\": -0.1081, \"times_seen\": 1.0}, {\"site\": 943, \"mutant\": \"A\", \"escape\": 0.002991945404812367, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.3291, \"times_seen\": 14.0}, {\"site\": 943, \"mutant\": \"C\", \"escape\": 0.5910928386437917, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.1577, \"times_seen\": 4.0}, {\"site\": 943, \"mutant\": \"D\", \"escape\": -0.013408145428810333, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.2621, \"times_seen\": 77.0}, {\"site\": 943, \"mutant\": \"E\", \"escape\": -0.006793017017464598, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.3216, \"times_seen\": 10.0}, {\"site\": 943, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 943, \"mutant\": \"R\", \"escape\": 0.016613869273975637, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.0948, \"times_seen\": 21.0}, {\"site\": 943, \"mutant\": \"S\", \"escape\": 0.3882407199521094, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": 0.2133, \"times_seen\": 5.0}, {\"site\": 943, \"mutant\": \"T\", \"escape\": 0.011833823628887477, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.4021, \"times_seen\": 2.0}, {\"site\": 943, \"mutant\": \"V\", \"escape\": -0.008125291187933452, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.25, \"times_seen\": 21.0}, {\"site\": 943, \"mutant\": \"W\", \"escape\": 0.06310588062731039, \"epitope\": \"epitope 1\", \"reference_site\": \"946\", \"functional effect\": -0.7046, \"times_seen\": 7.0}, {\"site\": 944, \"mutant\": \"E\", \"escape\": -0.014215918049719367, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": -0.3957, \"times_seen\": 12.0}, {\"site\": 944, \"mutant\": \"G\", \"escape\": 0.002805666653915266, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": -1.64, \"times_seen\": 1.0}, {\"site\": 944, \"mutant\": \"I\", \"escape\": 0.014585447915984559, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 944, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 944, \"mutant\": \"N\", \"escape\": 0.014852891442686745, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": -0.2645, \"times_seen\": 10.0}, {\"site\": 944, \"mutant\": \"R\", \"escape\": 0.6603206545231354, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.3292, \"times_seen\": 4.0}, {\"site\": 944, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"947\", \"functional effect\": 0.1167, \"times_seen\": null}, {\"site\": 945, \"mutant\": \"F\", \"escape\": -0.012858708898365013, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -2.9634, \"times_seen\": 5.0}, {\"site\": 945, \"mutant\": \"H\", \"escape\": -0.002874014497730893, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -2.0743, \"times_seen\": 1.0}, {\"site\": 945, \"mutant\": \"I\", \"escape\": 0.05386593186204321, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -0.1733, \"times_seen\": 27.0}, {\"site\": 945, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 945, \"mutant\": \"M\", \"escape\": -0.006357289149171309, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 945, \"mutant\": \"P\", \"escape\": -0.0030406178524587228, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -3.126, \"times_seen\": 1.0}, {\"site\": 945, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"948\", \"functional effect\": -3.2637, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -2.5809, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"E\", \"escape\": -0.0019570324934600537, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": 0.096, \"times_seen\": 4.0}, {\"site\": 946, \"mutant\": \"H\", \"escape\": -0.023710004728675432, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -0.6883, \"times_seen\": 15.0}, {\"site\": 946, \"mutant\": \"K\", \"escape\": -0.007759683137106386, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -1.4144, \"times_seen\": 2.0}, {\"site\": 946, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -1.3087, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"R\", \"escape\": -0.215404480061062, \"epitope\": \"epitope 1\", \"reference_site\": \"949\", \"functional effect\": -1.6677, \"times_seen\": 18.0}, {\"site\": 947, \"mutant\": \"*\", \"escape\": -0.005387226582334699, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -2.9788, \"times_seen\": 3.0}, {\"site\": 947, \"mutant\": \"A\", \"escape\": -0.09696328949488202, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.3039, \"times_seen\": 49.0}, {\"site\": 947, \"mutant\": \"C\", \"escape\": -0.004263723991561772, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.4446, \"times_seen\": 10.0}, {\"site\": 947, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 947, \"mutant\": \"E\", \"escape\": -0.16956301612720046, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.2797, \"times_seen\": 66.0}, {\"site\": 947, \"mutant\": \"F\", \"escape\": -0.052973922715642704, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.3733, \"times_seen\": 19.0}, {\"site\": 947, \"mutant\": \"G\", \"escape\": 0.0777504968583497, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.6903, \"times_seen\": 71.0}, {\"site\": 947, \"mutant\": \"H\", \"escape\": -1.7275195487244972, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.6543, \"times_seen\": 18.0}, {\"site\": 947, \"mutant\": \"I\", \"escape\": -0.010126595069475119, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.0843, \"times_seen\": 26.0}, {\"site\": 947, \"mutant\": \"K\", \"escape\": -0.9834526090882448, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.4556, \"times_seen\": 23.0}, {\"site\": 947, \"mutant\": \"L\", \"escape\": 0.23053649583373517, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.9281, \"times_seen\": 29.0}, {\"site\": 947, \"mutant\": \"M\", \"escape\": -0.036079915087401854, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.2803, \"times_seen\": 12.0}, {\"site\": 947, \"mutant\": \"N\", \"escape\": -0.019085822577714174, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.1851, \"times_seen\": 47.0}, {\"site\": 947, \"mutant\": \"P\", \"escape\": 0.01451860075874789, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -2.5739, \"times_seen\": 3.0}, {\"site\": 947, \"mutant\": \"Q\", \"escape\": 0.07328780834270057, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.3614, \"times_seen\": 24.0}, {\"site\": 947, \"mutant\": \"R\", \"escape\": -1.5592865980341741, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.5694, \"times_seen\": 43.0}, {\"site\": 947, \"mutant\": \"S\", \"escape\": 0.5249703916233592, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.507, \"times_seen\": 63.0}, {\"site\": 947, \"mutant\": \"T\", \"escape\": -0.008425133005648924, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.3584, \"times_seen\": 23.0}, {\"site\": 947, \"mutant\": \"V\", \"escape\": 0.004273140690702663, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -0.9083, \"times_seen\": 32.0}, {\"site\": 947, \"mutant\": \"W\", \"escape\": -0.05325295960044629, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.3042, \"times_seen\": 22.0}, {\"site\": 947, \"mutant\": \"Y\", \"escape\": 0.00538361040663205, \"epitope\": \"epitope 1\", \"reference_site\": \"950\", \"functional effect\": -1.1047, \"times_seen\": 20.0}, {\"site\": 948, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -2.7742, \"times_seen\": null}, {\"site\": 948, \"mutant\": \"E\", \"escape\": -0.003369539926230818, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -1.763, \"times_seen\": 1.0}, {\"site\": 948, \"mutant\": \"L\", \"escape\": -0.0027318225579225563, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -1.4484, \"times_seen\": 3.0}, {\"site\": 948, \"mutant\": \"M\", \"escape\": 0.004607377623677549, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": -1.2045, \"times_seen\": 17.0}, {\"site\": 948, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"951\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 949, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 949, \"mutant\": \"A\", \"escape\": 0.005441801631989626, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.0805, \"times_seen\": 6.0}, {\"site\": 949, \"mutant\": \"C\", \"escape\": 0.011250041519576719, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -2.3314, \"times_seen\": 3.0}, {\"site\": 949, \"mutant\": \"F\", \"escape\": -0.009359186159016389, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.4429, \"times_seen\": 18.0}, {\"site\": 949, \"mutant\": \"H\", \"escape\": -0.01142835686242679, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.7319, \"times_seen\": 3.0}, {\"site\": 949, \"mutant\": \"I\", \"escape\": -0.15116074746516095, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -0.0287, \"times_seen\": 24.0}, {\"site\": 949, \"mutant\": \"L\", \"escape\": -0.011266263093026009, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.4796, \"times_seen\": 5.0}, {\"site\": 949, \"mutant\": \"M\", \"escape\": -0.01920723245582046, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": -1.1134, \"times_seen\": 8.0}, {\"site\": 949, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"952\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"D\", \"escape\": -0.006236299399038546, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 950, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.1214, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"K\", \"escape\": -0.0028517816544463867, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.9502, \"times_seen\": 6.0}, {\"site\": 950, \"mutant\": \"L\", \"escape\": 0.03324750408048172, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.8839, \"times_seen\": 3.0}, {\"site\": 950, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"S\", \"escape\": -0.025364998975201822, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.5432, \"times_seen\": 24.0}, {\"site\": 950, \"mutant\": \"T\", \"escape\": 0.5187887088072909, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.1638, \"times_seen\": 18.0}, {\"site\": 950, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"953\", \"functional effect\": -0.5388, \"times_seen\": null}, {\"site\": 951, \"mutant\": \"*\", \"escape\": -0.025799702604856554, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -2.3194, \"times_seen\": 8.0}, {\"site\": 951, \"mutant\": \"-\", \"escape\": -0.0033985996473635234, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -0.8217, \"times_seen\": 1.0}, {\"site\": 951, \"mutant\": \"A\", \"escape\": -0.31052221364697585, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.354, \"times_seen\": 80.0}, {\"site\": 951, \"mutant\": \"C\", \"escape\": -0.4223203395822755, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -0.3075, \"times_seen\": 63.0}, {\"site\": 951, \"mutant\": \"D\", \"escape\": -0.03899024856596337, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.054, \"times_seen\": 79.0}, {\"site\": 951, \"mutant\": \"E\", \"escape\": 0.5106403685199805, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1434, \"times_seen\": 34.0}, {\"site\": 951, \"mutant\": \"F\", \"escape\": -0.13168945710919944, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.0385, \"times_seen\": 58.0}, {\"site\": 951, \"mutant\": \"G\", \"escape\": 0.02894445253437177, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -0.1723, \"times_seen\": 66.0}, {\"site\": 951, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 951, \"mutant\": \"I\", \"escape\": 0.3943405795652047, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.2681, \"times_seen\": 37.0}, {\"site\": 951, \"mutant\": \"K\", \"escape\": 0.011851142348984649, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.2298, \"times_seen\": 59.0}, {\"site\": 951, \"mutant\": \"L\", \"escape\": 0.0017150515829724513, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1357, \"times_seen\": 179.0}, {\"site\": 951, \"mutant\": \"M\", \"escape\": -0.062172628814205315, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3673, \"times_seen\": 35.0}, {\"site\": 951, \"mutant\": \"N\", \"escape\": -0.08593040083399084, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1962, \"times_seen\": 63.0}, {\"site\": 951, \"mutant\": \"P\", \"escape\": 0.020139557183307885, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": -2.4186, \"times_seen\": 16.0}, {\"site\": 951, \"mutant\": \"Q\", \"escape\": 0.06575571146149774, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3579, \"times_seen\": 114.0}, {\"site\": 951, \"mutant\": \"R\", \"escape\": -0.015285744807181357, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.2391, \"times_seen\": 181.0}, {\"site\": 951, \"mutant\": \"S\", \"escape\": 0.2390817702469565, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.157, \"times_seen\": 161.0}, {\"site\": 951, \"mutant\": \"T\", \"escape\": 0.006807009636299868, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3262, \"times_seen\": 66.0}, {\"site\": 951, \"mutant\": \"V\", \"escape\": -0.3791678201478225, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.3553, \"times_seen\": 113.0}, {\"site\": 951, \"mutant\": \"W\", \"escape\": -0.01945956840164095, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.1018, \"times_seen\": 29.0}, {\"site\": 951, \"mutant\": \"Y\", \"escape\": -0.04161788957003386, \"epitope\": \"epitope 1\", \"reference_site\": \"954\", \"functional effect\": 0.0851, \"times_seen\": 67.0}, {\"site\": 952, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"D\", \"escape\": -0.009540460331966599, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -2.0274, \"times_seen\": 13.0}, {\"site\": 952, \"mutant\": \"F\", \"escape\": -0.042624248044575236, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -1.5595, \"times_seen\": 9.0}, {\"site\": 952, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"H\", \"escape\": 0.002913216653968951, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -0.2737, \"times_seen\": 12.0}, {\"site\": 952, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -3.1284, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"K\", \"escape\": -0.043682663653909666, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 952, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"S\", \"escape\": 0.0005107555582775772, \"epitope\": \"epitope 1\", \"reference_site\": \"955\", \"functional effect\": -0.1368, \"times_seen\": 1.0}, {\"site\": 953, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 953, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 953, \"mutant\": \"D\", \"escape\": -0.008891153534784386, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -1.2581, \"times_seen\": 5.0}, {\"site\": 953, \"mutant\": \"F\", \"escape\": -0.016592042950577555, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.3312, \"times_seen\": 8.0}, {\"site\": 953, \"mutant\": \"H\", \"escape\": 0.0034284622757857846, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.1056, \"times_seen\": 10.0}, {\"site\": 953, \"mutant\": \"K\", \"escape\": -0.019004243996461737, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.9177, \"times_seen\": 9.0}, {\"site\": 953, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -2.0292, \"times_seen\": null}, {\"site\": 953, \"mutant\": \"S\", \"escape\": 0.004726521699558563, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.1719, \"times_seen\": 16.0}, {\"site\": 953, \"mutant\": \"T\", \"escape\": -0.01810461277294344, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": -0.122, \"times_seen\": 17.0}, {\"site\": 953, \"mutant\": \"V\", \"escape\": -0.01329738162525156, \"epitope\": \"epitope 1\", \"reference_site\": \"956\", \"functional effect\": 0.3986, \"times_seen\": 8.0}, {\"site\": 954, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -2.7546, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"E\", \"escape\": 0.0907420462797807, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.0619, \"times_seen\": 32.0}, {\"site\": 954, \"mutant\": \"H\", \"escape\": -0.04528529179004617, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.0952, \"times_seen\": 27.0}, {\"site\": 954, \"mutant\": \"K\", \"escape\": 0.017738420917429876, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.5593, \"times_seen\": 17.0}, {\"site\": 954, \"mutant\": \"L\", \"escape\": 0.10551361473991307, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.2516, \"times_seen\": 77.0}, {\"site\": 954, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -3.0958, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"R\", \"escape\": 0.0410192856556939, \"epitope\": \"epitope 1\", \"reference_site\": \"957\", \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 955, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"D\", \"escape\": -0.0031594775601753032, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -0.3862, \"times_seen\": 1.0}, {\"site\": 955, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -2.0828, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"L\", \"escape\": 0.06477169255412277, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -0.9988, \"times_seen\": 9.0}, {\"site\": 955, \"mutant\": \"M\", \"escape\": 0.01856887861570139, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -1.2735, \"times_seen\": 3.0}, {\"site\": 955, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -2.4826, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"S\", \"escape\": 0.0055377498230588865, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -0.54, \"times_seen\": 39.0}, {\"site\": 955, \"mutant\": \"T\", \"escape\": 0.009937106812130322, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -1.6606, \"times_seen\": 13.0}, {\"site\": 955, \"mutant\": \"V\", \"escape\": -0.013159516887634466, \"epitope\": \"epitope 1\", \"reference_site\": \"958\", \"functional effect\": -2.7862, \"times_seen\": 5.0}, {\"site\": 956, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 956, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 956, \"mutant\": \"M\", \"escape\": -0.9111045024797622, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -0.2794, \"times_seen\": 2.0}, {\"site\": 956, \"mutant\": \"P\", \"escape\": -0.008516515125857034, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -2.7605, \"times_seen\": 2.0}, {\"site\": 956, \"mutant\": \"Q\", \"escape\": -0.008819284462534585, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -1.3264, \"times_seen\": 1.0}, {\"site\": 956, \"mutant\": \"R\", \"escape\": -0.011114259016436331, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -0.2295, \"times_seen\": 1.0}, {\"site\": 956, \"mutant\": \"V\", \"escape\": -0.007497592996621322, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -1.2439, \"times_seen\": 1.0}, {\"site\": 956, \"mutant\": \"W\", \"escape\": -0.06564299471787804, \"epitope\": \"epitope 1\", \"reference_site\": \"959\", \"functional effect\": -2.1038, \"times_seen\": 6.0}, {\"site\": 957, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"A\", \"escape\": -1.063599736100207, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.1938, \"times_seen\": 9.0}, {\"site\": 957, \"mutant\": \"D\", \"escape\": -0.026645868945739556, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 957, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"H\", \"escape\": -0.003246295897761257, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.9805, \"times_seen\": 1.0}, {\"site\": 957, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.4506, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"K\", \"escape\": -0.02420068520763257, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.3297, \"times_seen\": 11.0}, {\"site\": 957, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"S\", \"escape\": -0.02005478662893218, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.0866, \"times_seen\": 21.0}, {\"site\": 957, \"mutant\": \"T\", \"escape\": -0.023423959160885313, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -0.2975, \"times_seen\": 11.0}, {\"site\": 957, \"mutant\": \"Y\", \"escape\": -0.007791756003061176, \"epitope\": \"epitope 1\", \"reference_site\": \"960\", \"functional effect\": -1.2786, \"times_seen\": 1.0}, {\"site\": 958, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 958, \"mutant\": \"A\", \"escape\": -0.055082975348104316, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.4658, \"times_seen\": 43.0}, {\"site\": 958, \"mutant\": \"I\", \"escape\": 0.0652081381288577, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.425, \"times_seen\": 4.0}, {\"site\": 958, \"mutant\": \"M\", \"escape\": -0.03696470679018975, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.2616, \"times_seen\": 24.0}, {\"site\": 958, \"mutant\": \"N\", \"escape\": -1.4612749416571562, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": 0.2815, \"times_seen\": 5.0}, {\"site\": 958, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -2.8991, \"times_seen\": null}, {\"site\": 958, \"mutant\": \"R\", \"escape\": -0.02964700862584963, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.9293, \"times_seen\": 10.0}, {\"site\": 958, \"mutant\": \"S\", \"escape\": -0.016448180670008784, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": -0.2061, \"times_seen\": 27.0}, {\"site\": 958, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"961\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"-\", \"escape\": -0.0019485902936968163, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 959, \"mutant\": \"K\", \"escape\": -0.0057286566948420905, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.8737, \"times_seen\": 2.0}, {\"site\": 959, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"M\", \"escape\": 0.012307914635755495, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.8218, \"times_seen\": 2.0}, {\"site\": 959, \"mutant\": \"P\", \"escape\": -0.006833465822650308, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.7538, \"times_seen\": 3.0}, {\"site\": 959, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.8229, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"T\", \"escape\": 0.011616588399104207, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": -2.7581, \"times_seen\": 3.0}, {\"site\": 959, \"mutant\": \"V\", \"escape\": -0.0030248290502039423, \"epitope\": \"epitope 1\", \"reference_site\": \"962\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 960, \"mutant\": \"-\", \"escape\": -0.002711123918223882, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 960, \"mutant\": \"A\", \"escape\": -0.0048504301598021795, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -2.5528, \"times_seen\": 3.0}, {\"site\": 960, \"mutant\": \"I\", \"escape\": -0.07717588217118218, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.3528, \"times_seen\": 30.0}, {\"site\": 960, \"mutant\": \"L\", \"escape\": 0.01655418624724582, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.5852, \"times_seen\": 26.0}, {\"site\": 960, \"mutant\": \"M\", \"escape\": -0.021790785526864677, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.4396, \"times_seen\": 31.0}, {\"site\": 960, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": -0.911, \"times_seen\": null}, {\"site\": 960, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"963\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 961, \"mutant\": \"-\", \"escape\": -0.0020222342787325504, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 961, \"mutant\": \"E\", \"escape\": -3.563335028918974e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.1421, \"times_seen\": 1.0}, {\"site\": 961, \"mutant\": \"H\", \"escape\": -0.015246775868100764, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.1207, \"times_seen\": 3.0}, {\"site\": 961, \"mutant\": \"I\", \"escape\": -0.027445017430140457, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.0698, \"times_seen\": 13.0}, {\"site\": 961, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 961, \"mutant\": \"L\", \"escape\": -0.02846970990002195, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": 0.0106, \"times_seen\": 11.0}, {\"site\": 961, \"mutant\": \"M\", \"escape\": -0.0004746222915684483, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 961, \"mutant\": \"N\", \"escape\": 0.07374401218029276, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.0124, \"times_seen\": 20.0}, {\"site\": 961, \"mutant\": \"R\", \"escape\": 0.0374927810470496, \"epitope\": \"epitope 1\", \"reference_site\": \"964\", \"functional effect\": -0.1502, \"times_seen\": 22.0}, {\"site\": 962, \"mutant\": \"*\", \"escape\": -0.008504090846815809, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -2.4019, \"times_seen\": 2.0}, {\"site\": 962, \"mutant\": \"-\", \"escape\": -0.0029070943559374104, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 962, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.2766, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.712, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"K\", \"escape\": -0.07671221131338625, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.4059, \"times_seen\": 30.0}, {\"site\": 962, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": 0.0708, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"N\", \"escape\": -0.01703990788240636, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -0.3547, \"times_seen\": 12.0}, {\"site\": 962, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -2.2766, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"R\", \"escape\": -0.0032092617544669548, \"epitope\": \"epitope 1\", \"reference_site\": \"965\", \"functional effect\": -2.2174, \"times_seen\": 1.0}, {\"site\": 963, \"mutant\": \"-\", \"escape\": -0.0021693833340959653, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 963, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -2.6953, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -1.7631, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -2.6644, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -3.0577, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"966\", \"functional effect\": -2.7218, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"-\", \"escape\": -0.0022283893846653767, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 964, \"mutant\": \"A\", \"escape\": -0.01910022751323617, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.1633, \"times_seen\": 4.0}, {\"site\": 964, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -1.7587, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"F\", \"escape\": -0.0018296494727624208, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -1.6437, \"times_seen\": 1.0}, {\"site\": 964, \"mutant\": \"G\", \"escape\": -0.014647878214916253, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.3437, \"times_seen\": 5.0}, {\"site\": 964, \"mutant\": \"N\", \"escape\": -0.02118501032431359, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -2.0275, \"times_seen\": 10.0}, {\"site\": 964, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"R\", \"escape\": 0.011186400760255353, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -1.1687, \"times_seen\": 4.0}, {\"site\": 964, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"T\", \"escape\": 0.0019610127107341203, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -0.681, \"times_seen\": 24.0}, {\"site\": 964, \"mutant\": \"W\", \"escape\": -0.005446096107563586, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -2.4424, \"times_seen\": 3.0}, {\"site\": 964, \"mutant\": \"Y\", \"escape\": -0.0036264358327113217, \"epitope\": \"epitope 1\", \"reference_site\": \"967\", \"functional effect\": -2.1403, \"times_seen\": 1.0}, {\"site\": 965, \"mutant\": \"-\", \"escape\": -0.004851619341644297, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 965, \"mutant\": \"C\", \"escape\": 0.0257721476129581, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.6781, \"times_seen\": 52.0}, {\"site\": 965, \"mutant\": \"F\", \"escape\": -1.3617093384787295, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": 0.3242, \"times_seen\": 8.0}, {\"site\": 965, \"mutant\": \"G\", \"escape\": -0.01734542355336872, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -1.0771, \"times_seen\": 10.0}, {\"site\": 965, \"mutant\": \"I\", \"escape\": -0.018151979773205353, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.0723, \"times_seen\": 4.0}, {\"site\": 965, \"mutant\": \"N\", \"escape\": -0.015011553650225551, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": 0.3441, \"times_seen\": 23.0}, {\"site\": 965, \"mutant\": \"P\", \"escape\": -0.004581860861614231, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -2.4785, \"times_seen\": 3.0}, {\"site\": 965, \"mutant\": \"R\", \"escape\": -0.019043544579358127, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -1.1234, \"times_seen\": 5.0}, {\"site\": 965, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 965, \"mutant\": \"T\", \"escape\": -0.05933945819955744, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.0446, \"times_seen\": 21.0}, {\"site\": 965, \"mutant\": \"V\", \"escape\": -0.009657722914693526, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.0248, \"times_seen\": 19.0}, {\"site\": 965, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"968\", \"functional effect\": -0.1442, \"times_seen\": null}, {\"site\": 966, \"mutant\": \"*\", \"escape\": 0.02350839928574992, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.7391, \"times_seen\": 2.0}, {\"site\": 966, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 966, \"mutant\": \"A\", \"escape\": 0.0034814393338706727, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 966, \"mutant\": \"C\", \"escape\": 0.02655180026787984, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -1.6117, \"times_seen\": 17.0}, {\"site\": 966, \"mutant\": \"D\", \"escape\": -0.0019940494141044, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 966, \"mutant\": \"E\", \"escape\": -0.03842330084636341, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.5324, \"times_seen\": 9.0}, {\"site\": 966, \"mutant\": \"F\", \"escape\": -0.006784510530961334, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.4857, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"G\", \"escape\": -0.014548445928675699, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.262, \"times_seen\": 12.0}, {\"site\": 966, \"mutant\": \"H\", \"escape\": -0.01566544235578264, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.3963, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"I\", \"escape\": 0.04335632558365666, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.8676, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 966, \"mutant\": \"L\", \"escape\": -0.004097995204368854, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.2689, \"times_seen\": 10.0}, {\"site\": 966, \"mutant\": \"M\", \"escape\": 0.011812854757229112, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.9869, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"N\", \"escape\": -0.12486757248326079, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -1.4827, \"times_seen\": 55.0}, {\"site\": 966, \"mutant\": \"P\", \"escape\": -0.344574470764167, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -1.4039, \"times_seen\": 28.0}, {\"site\": 966, \"mutant\": \"Q\", \"escape\": 0.006515875373001931, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.3216, \"times_seen\": 24.0}, {\"site\": 966, \"mutant\": \"R\", \"escape\": -0.29114341039922836, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": 0.1338, \"times_seen\": 167.0}, {\"site\": 966, \"mutant\": \"S\", \"escape\": 0.14593392501853578, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -0.5279, \"times_seen\": 99.0}, {\"site\": 966, \"mutant\": \"T\", \"escape\": 0.03681273618068916, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": 0.1531, \"times_seen\": 71.0}, {\"site\": 966, \"mutant\": \"V\", \"escape\": 0.008564679078915035, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.642, \"times_seen\": 5.0}, {\"site\": 966, \"mutant\": \"W\", \"escape\": 0.005674136363201958, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.8316, \"times_seen\": 6.0}, {\"site\": 966, \"mutant\": \"Y\", \"escape\": -0.003997205412003491, \"epitope\": \"epitope 1\", \"reference_site\": \"969\", \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 967, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 967, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 967, \"mutant\": \"I\", \"escape\": -0.010874490614798627, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -2.9828, \"times_seen\": 1.0}, {\"site\": 967, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -2.7936, \"times_seen\": null}, {\"site\": 967, \"mutant\": \"S\", \"escape\": -0.005802074357419031, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 967, \"mutant\": \"Y\", \"escape\": -0.0006083887517921247, \"epitope\": \"epitope 1\", \"reference_site\": \"970\", \"functional effect\": -0.7589, \"times_seen\": 1.0}, {\"site\": 968, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.792, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.8535, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -3.0508, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"Q\", \"escape\": -0.0057389558437232115, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -3.0212, \"times_seen\": 1.0}, {\"site\": 968, \"mutant\": \"R\", \"escape\": -0.012509533936556794, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -1.9913, \"times_seen\": 4.0}, {\"site\": 968, \"mutant\": \"V\", \"escape\": 0.014183988951604982, \"epitope\": \"epitope 1\", \"reference_site\": \"971\", \"functional effect\": -2.7955, \"times_seen\": 5.0}, {\"site\": 969, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"C\", \"escape\": 0.03658141480111136, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -0.2237, \"times_seen\": 20.0}, {\"site\": 969, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.3768, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"M\", \"escape\": 0.006380403443580457, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.2134, \"times_seen\": 5.0}, {\"site\": 969, \"mutant\": \"S\", \"escape\": -0.04008676335513362, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.0949, \"times_seen\": 17.0}, {\"site\": 969, \"mutant\": \"T\", \"escape\": -0.016920067153868283, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -1.7998, \"times_seen\": 9.0}, {\"site\": 969, \"mutant\": \"V\", \"escape\": -0.01342685278712427, \"epitope\": \"epitope 1\", \"reference_site\": \"972\", \"functional effect\": -2.9983, \"times_seen\": 5.0}, {\"site\": 970, \"mutant\": \"F\", \"escape\": -0.010668169971114068, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -1.6201, \"times_seen\": 9.0}, {\"site\": 970, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 970, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 970, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -2.0482, \"times_seen\": null}, {\"site\": 970, \"mutant\": \"T\", \"escape\": 0.019806144330956715, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -0.172, \"times_seen\": 5.0}, {\"site\": 970, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"973\", \"functional effect\": -0.1562, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"-\", \"escape\": -0.0034944392744967164, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.1772, \"times_seen\": 1.0}, {\"site\": 971, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.9942, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -1.0597, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"K\", \"escape\": -0.0006301071154632414, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.9803, \"times_seen\": 1.0}, {\"site\": 971, \"mutant\": \"P\", \"escape\": -0.003134344616889436, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -0.3972, \"times_seen\": 2.0}, {\"site\": 971, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"T\", \"escape\": 0.002021444014845155, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": 0.0648, \"times_seen\": 1.0}, {\"site\": 971, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"974\", \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 972, \"mutant\": \"A\", \"escape\": -0.0037800807271728114, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": 0.191, \"times_seen\": 2.0}, {\"site\": 972, \"mutant\": \"F\", \"escape\": -0.005029385587126474, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -0.7476, \"times_seen\": 1.0}, {\"site\": 972, \"mutant\": \"M\", \"escape\": -0.0080506227157159, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.6768, \"times_seen\": 3.0}, {\"site\": 972, \"mutant\": \"N\", \"escape\": -0.022115099642762443, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": 0.4086, \"times_seen\": 21.0}, {\"site\": 972, \"mutant\": \"P\", \"escape\": -0.007485072854826944, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -0.1918, \"times_seen\": 6.0}, {\"site\": 972, \"mutant\": \"R\", \"escape\": -0.018839936666695204, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.952, \"times_seen\": 4.0}, {\"site\": 972, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 972, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 972, \"mutant\": \"Y\", \"escape\": -0.003270085849953021, \"epitope\": \"epitope 1\", \"reference_site\": \"975\", \"functional effect\": -2.3569, \"times_seen\": 1.0}, {\"site\": 973, \"mutant\": \"A\", \"escape\": -0.013329288844276132, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": 0.309, \"times_seen\": 27.0}, {\"site\": 973, \"mutant\": \"E\", \"escape\": -0.022846148188916976, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": 0.0741, \"times_seen\": 4.0}, {\"site\": 973, \"mutant\": \"F\", \"escape\": -0.09970196942494979, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.2778, \"times_seen\": 40.0}, {\"site\": 973, \"mutant\": \"G\", \"escape\": -0.03928381502448905, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.3156, \"times_seen\": 25.0}, {\"site\": 973, \"mutant\": \"I\", \"escape\": -0.021260087996903248, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.3747, \"times_seen\": 18.0}, {\"site\": 973, \"mutant\": \"L\", \"escape\": -0.010734432577881337, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.9486, \"times_seen\": 4.0}, {\"site\": 973, \"mutant\": \"M\", \"escape\": -0.06848386960614863, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": -0.3943, \"times_seen\": 19.0}, {\"site\": 973, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"976\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"M\", \"escape\": -0.0031532343900247672, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": 0.0639, \"times_seen\": 6.0}, {\"site\": 974, \"mutant\": \"P\", \"escape\": 0.03148374822483852, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -2.6936, \"times_seen\": 14.0}, {\"site\": 974, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -3.0155, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"S\", \"escape\": -0.006367408376593824, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": -2.8464, \"times_seen\": 2.0}, {\"site\": 974, \"mutant\": \"V\", \"escape\": -0.03970263206646233, \"epitope\": \"epitope 1\", \"reference_site\": \"977\", \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 975, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.6369, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"F\", \"escape\": -0.017257306339884464, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.7606, \"times_seen\": 8.0}, {\"site\": 975, \"mutant\": \"H\", \"escape\": -0.009034127862067271, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -0.2445, \"times_seen\": 3.0}, {\"site\": 975, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -2.6303, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"S\", \"escape\": 0.0023089921243505673, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": 0.0876, \"times_seen\": 16.0}, {\"site\": 975, \"mutant\": \"Y\", \"escape\": -0.0035859037046969107, \"epitope\": \"epitope 1\", \"reference_site\": \"978\", \"functional effect\": -2.0323, \"times_seen\": 1.0}, {\"site\": 976, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"E\", \"escape\": -0.003269351298271511, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": 0.2967, \"times_seen\": 7.0}, {\"site\": 976, \"mutant\": \"G\", \"escape\": -0.011918726496778486, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -2.5281, \"times_seen\": 3.0}, {\"site\": 976, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -1.9653, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"N\", \"escape\": 0.014683915817123354, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -2.4352, \"times_seen\": 2.0}, {\"site\": 976, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"V\", \"escape\": -0.0032363888065200766, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -0.0933, \"times_seen\": 1.0}, {\"site\": 976, \"mutant\": \"Y\", \"escape\": 0.015052689118925534, \"epitope\": \"epitope 1\", \"reference_site\": \"979\", \"functional effect\": -2.3506, \"times_seen\": 5.0}, {\"site\": 977, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"F\", \"escape\": -0.0063360482191835744, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -2.741, \"times_seen\": 2.0}, {\"site\": 977, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"L\", \"escape\": -0.03538029407204705, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -1.4023, \"times_seen\": 3.0}, {\"site\": 977, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -3.0261, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -2.7277, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -3.1298, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"V\", \"escape\": -0.0103011492706148, \"epitope\": \"epitope 1\", \"reference_site\": \"980\", \"functional effect\": -1.8607, \"times_seen\": 3.0}, {\"site\": 978, \"mutant\": \"*\", \"escape\": -0.007523118691423797, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.6138, \"times_seen\": 4.0}, {\"site\": 978, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -1.8075, \"times_seen\": null}, {\"site\": 978, \"mutant\": \"A\", \"escape\": -0.3186128462743706, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.1042, \"times_seen\": 108.0}, {\"site\": 978, \"mutant\": \"C\", \"escape\": -0.06931609948823536, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.1214, \"times_seen\": 69.0}, {\"site\": 978, \"mutant\": \"D\", \"escape\": -0.5721471752639392, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -1.0959, \"times_seen\": 48.0}, {\"site\": 978, \"mutant\": \"E\", \"escape\": -0.05200425493203509, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4195, \"times_seen\": 50.0}, {\"site\": 978, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 978, \"mutant\": \"G\", \"escape\": -0.026800752315024115, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -1.8415, \"times_seen\": 45.0}, {\"site\": 978, \"mutant\": \"H\", \"escape\": 0.02209825436132497, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.8577, \"times_seen\": 43.0}, {\"site\": 978, \"mutant\": \"I\", \"escape\": -0.5089643016263313, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4444, \"times_seen\": 120.0}, {\"site\": 978, \"mutant\": \"K\", \"escape\": 0.04615373151885433, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.1794, \"times_seen\": 22.0}, {\"site\": 978, \"mutant\": \"L\", \"escape\": 0.07172649882281072, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.2322, \"times_seen\": 117.0}, {\"site\": 978, \"mutant\": \"M\", \"escape\": -0.04083405891968107, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.1087, \"times_seen\": 37.0}, {\"site\": 978, \"mutant\": \"N\", \"escape\": -0.04346448328731145, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.4181, \"times_seen\": 48.0}, {\"site\": 978, \"mutant\": \"P\", \"escape\": 0.24244107537590087, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.6849, \"times_seen\": 38.0}, {\"site\": 978, \"mutant\": \"Q\", \"escape\": -0.01554792426069793, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -0.5073, \"times_seen\": 24.0}, {\"site\": 978, \"mutant\": \"R\", \"escape\": -0.015227856426504881, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": -2.2984, \"times_seen\": 48.0}, {\"site\": 978, \"mutant\": \"S\", \"escape\": -0.13108554548629467, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4298, \"times_seen\": 154.0}, {\"site\": 978, \"mutant\": \"T\", \"escape\": -0.05723725750664752, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4444, \"times_seen\": 89.0}, {\"site\": 978, \"mutant\": \"V\", \"escape\": -0.5329829464228942, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.4444, \"times_seen\": 124.0}, {\"site\": 978, \"mutant\": \"W\", \"escape\": 0.15982640632266149, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.3058, \"times_seen\": 44.0}, {\"site\": 978, \"mutant\": \"Y\", \"escape\": 0.36589528437240354, \"epitope\": \"epitope 1\", \"reference_site\": \"981\", \"functional effect\": 0.3651, \"times_seen\": 89.0}, {\"site\": 979, \"mutant\": \"*\", \"escape\": 0.019370993873296535, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.4364, \"times_seen\": 3.0}, {\"site\": 979, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 979, \"mutant\": \"A\", \"escape\": 0.3996478592557519, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": 0.2506, \"times_seen\": 109.0}, {\"site\": 979, \"mutant\": \"C\", \"escape\": -0.021546867081108284, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.437, \"times_seen\": 54.0}, {\"site\": 979, \"mutant\": \"D\", \"escape\": 0.0020163613560660724, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.5303, \"times_seen\": 31.0}, {\"site\": 979, \"mutant\": \"E\", \"escape\": -1.1659997880846273, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.2212, \"times_seen\": 23.0}, {\"site\": 979, \"mutant\": \"F\", \"escape\": 0.023342965951484104, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.1923, \"times_seen\": 12.0}, {\"site\": 979, \"mutant\": \"G\", \"escape\": -0.10760822298583766, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.4425, \"times_seen\": 126.0}, {\"site\": 979, \"mutant\": \"H\", \"escape\": 0.012564827919123058, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.3799, \"times_seen\": 16.0}, {\"site\": 979, \"mutant\": \"I\", \"escape\": -0.364998200500065, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.0113, \"times_seen\": 44.0}, {\"site\": 979, \"mutant\": \"K\", \"escape\": -0.0483617473475794, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.4314, \"times_seen\": 6.0}, {\"site\": 979, \"mutant\": \"L\", \"escape\": 0.031098603069092588, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.0381, \"times_seen\": 68.0}, {\"site\": 979, \"mutant\": \"M\", \"escape\": -0.01740079743902433, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.3015, \"times_seen\": 32.0}, {\"site\": 979, \"mutant\": \"N\", \"escape\": -0.1917581515721374, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.2317, \"times_seen\": 79.0}, {\"site\": 979, \"mutant\": \"P\", \"escape\": 0.13666449186163457, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.592, \"times_seen\": 72.0}, {\"site\": 979, \"mutant\": \"Q\", \"escape\": -0.004674243701365891, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.6221, \"times_seen\": 29.0}, {\"site\": 979, \"mutant\": \"R\", \"escape\": -0.052145426598522705, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -2.7336, \"times_seen\": 29.0}, {\"site\": 979, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 979, \"mutant\": \"T\", \"escape\": 0.02515873817975409, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.4339, \"times_seen\": 74.0}, {\"site\": 979, \"mutant\": \"V\", \"escape\": 0.015510637780183661, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -0.4688, \"times_seen\": 63.0}, {\"site\": 979, \"mutant\": \"W\", \"escape\": -0.011566355076393748, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.9806, \"times_seen\": 18.0}, {\"site\": 979, \"mutant\": \"Y\", \"escape\": 0.03201605168855031, \"epitope\": \"epitope 1\", \"reference_site\": \"982\", \"functional effect\": -1.5874, \"times_seen\": 20.0}, {\"site\": 980, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.6466, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"I\", \"escape\": -0.015465447174858128, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -1.4676, \"times_seen\": 5.0}, {\"site\": 980, \"mutant\": \"K\", \"escape\": -0.5501635713938913, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -1.359, \"times_seen\": 21.0}, {\"site\": 980, \"mutant\": \"N\", \"escape\": 0.0072063004342942496, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.8738, \"times_seen\": 3.0}, {\"site\": 980, \"mutant\": \"Q\", \"escape\": -0.006349656720164819, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.0455, \"times_seen\": 8.0}, {\"site\": 980, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -2.3742, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"T\", \"escape\": -0.007220871295117598, \"epitope\": \"epitope 1\", \"reference_site\": \"983\", \"functional effect\": -3.1267, \"times_seen\": 1.0}, {\"site\": 981, \"mutant\": \"F\", \"escape\": -0.057469598544906755, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": 0.0263, \"times_seen\": 15.0}, {\"site\": 981, \"mutant\": \"K\", \"escape\": -0.0033692492534670515, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -1.2901, \"times_seen\": 1.0}, {\"site\": 981, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 981, \"mutant\": \"M\", \"escape\": -0.021286601762318946, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -0.1847, \"times_seen\": 8.0}, {\"site\": 981, \"mutant\": \"P\", \"escape\": -0.02111173066841636, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -2.9773, \"times_seen\": 5.0}, {\"site\": 981, \"mutant\": \"Q\", \"escape\": 0.0012913229334091147, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -2.6755, \"times_seen\": 1.0}, {\"site\": 981, \"mutant\": \"R\", \"escape\": -0.005592200883909534, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -2.6018, \"times_seen\": 2.0}, {\"site\": 981, \"mutant\": \"V\", \"escape\": 0.01746024183573565, \"epitope\": \"epitope 1\", \"reference_site\": \"984\", \"functional effect\": -1.3383, \"times_seen\": 2.0}, {\"site\": 982, \"mutant\": \"A\", \"escape\": -0.05586751093144807, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -1.3752, \"times_seen\": 16.0}, {\"site\": 982, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 982, \"mutant\": \"E\", \"escape\": -0.01676772449444448, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.6096, \"times_seen\": 6.0}, {\"site\": 982, \"mutant\": \"G\", \"escape\": -0.008363272098712992, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.8612, \"times_seen\": 1.0}, {\"site\": 982, \"mutant\": \"H\", \"escape\": 0.0040314233381701795, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -1.5046, \"times_seen\": 1.0}, {\"site\": 982, \"mutant\": \"N\", \"escape\": -1.7164706971556607, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.1631, \"times_seen\": 39.0}, {\"site\": 982, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 982, \"mutant\": \"T\", \"escape\": 0.5704433391269007, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -0.6573, \"times_seen\": 31.0}, {\"site\": 982, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -2.4547, \"times_seen\": null}, {\"site\": 982, \"mutant\": \"Y\", \"escape\": -0.004382978150985759, \"epitope\": \"epitope 1\", \"reference_site\": \"985\", \"functional effect\": -3.054, \"times_seen\": 1.0}, {\"site\": 983, \"mutant\": \"E\", \"escape\": -0.004516372044279417, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.7122, \"times_seen\": 3.0}, {\"site\": 983, \"mutant\": \"G\", \"escape\": -0.0327848396490262, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.7656, \"times_seen\": 1.0}, {\"site\": 983, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 983, \"mutant\": \"M\", \"escape\": 0.0191441955931245, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.0602, \"times_seen\": 4.0}, {\"site\": 983, \"mutant\": \"N\", \"escape\": 0.821283770020664, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.3265, \"times_seen\": 26.0}, {\"site\": 983, \"mutant\": \"P\", \"escape\": 1.182608997871498, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -2.5728, \"times_seen\": 12.0}, {\"site\": 983, \"mutant\": \"Q\", \"escape\": -0.06847444311092135, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.5062, \"times_seen\": 26.0}, {\"site\": 983, \"mutant\": \"R\", \"escape\": -0.06730742155967175, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": -0.1729, \"times_seen\": 92.0}, {\"site\": 983, \"mutant\": \"T\", \"escape\": 0.011268845747244467, \"epitope\": \"epitope 1\", \"reference_site\": \"986\", \"functional effect\": 0.0755, \"times_seen\": 12.0}, {\"site\": 984, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 984, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.6678, \"times_seen\": null}, {\"site\": 984, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.3691, \"times_seen\": null}, {\"site\": 984, \"mutant\": \"F\", \"escape\": 0.007687914940969992, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -0.0256, \"times_seen\": 38.0}, {\"site\": 984, \"mutant\": \"G\", \"escape\": 0.018007689485523174, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.0631, \"times_seen\": 1.0}, {\"site\": 984, \"mutant\": \"I\", \"escape\": 0.0005172866877855023, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -0.6662, \"times_seen\": 13.0}, {\"site\": 984, \"mutant\": \"L\", \"escape\": 0.013981813502028836, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -2.2332, \"times_seen\": 10.0}, {\"site\": 984, \"mutant\": \"M\", \"escape\": -0.0023687956369995346, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": -0.1031, \"times_seen\": 7.0}, {\"site\": 984, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"987\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.4746, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"D\", \"escape\": -0.014399842101237143, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": 0.1539, \"times_seen\": 8.0}, {\"site\": 985, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"G\", \"escape\": -0.041518308866289946, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.0405, \"times_seen\": 23.0}, {\"site\": 985, \"mutant\": \"K\", \"escape\": -0.5952910981453946, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -0.9251, \"times_seen\": 45.0}, {\"site\": 985, \"mutant\": \"L\", \"escape\": -0.03400088404552675, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.4406, \"times_seen\": 15.0}, {\"site\": 985, \"mutant\": \"R\", \"escape\": -0.0014338604171123053, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -0.801, \"times_seen\": 21.0}, {\"site\": 985, \"mutant\": \"V\", \"escape\": -0.002331601526830602, \"epitope\": \"epitope 1\", \"reference_site\": \"988\", \"functional effect\": -1.4355, \"times_seen\": 5.0}, {\"site\": 986, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 986, \"mutant\": \"C\", \"escape\": -0.01066410920168857, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.014, \"times_seen\": 4.0}, {\"site\": 986, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.5603, \"times_seen\": null}, {\"site\": 986, \"mutant\": \"G\", \"escape\": -0.00014762328612818442, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -1.1198, \"times_seen\": 1.0}, {\"site\": 986, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.9982, \"times_seen\": null}, {\"site\": 986, \"mutant\": \"P\", \"escape\": -0.0004737007553211766, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -3.2259, \"times_seen\": 1.0}, {\"site\": 986, \"mutant\": \"S\", \"escape\": 0.556789541168294, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -1.5174, \"times_seen\": 19.0}, {\"site\": 986, \"mutant\": \"T\", \"escape\": -0.0017785129668623468, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.7458, \"times_seen\": 2.0}, {\"site\": 986, \"mutant\": \"V\", \"escape\": -0.004069799329002212, \"epitope\": \"epitope 1\", \"reference_site\": \"989\", \"functional effect\": -2.5217, \"times_seen\": 13.0}, {\"site\": 987, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -2.9304, \"times_seen\": null}, {\"site\": 987, \"mutant\": \"A\", \"escape\": -0.02164072312174016, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.3188, \"times_seen\": 8.0}, {\"site\": 987, \"mutant\": \"D\", \"escape\": -0.029025050004432472, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.3632, \"times_seen\": 20.0}, {\"site\": 987, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 987, \"mutant\": \"G\", \"escape\": -0.10674340253508977, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -0.5187, \"times_seen\": 43.0}, {\"site\": 987, \"mutant\": \"K\", \"escape\": -0.11319992175643802, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -1.9929, \"times_seen\": 37.0}, {\"site\": 987, \"mutant\": \"N\", \"escape\": -0.03410661725062052, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 987, \"mutant\": \"Q\", \"escape\": -0.2460823560036666, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": 0.3215, \"times_seen\": 30.0}, {\"site\": 987, \"mutant\": \"V\", \"escape\": 0.00214029619900671, \"epitope\": \"epitope 1\", \"reference_site\": \"990\", \"functional effect\": -1.6432, \"times_seen\": 5.0}, {\"site\": 988, \"mutant\": \"A\", \"escape\": -0.006692580441848066, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -1.6111, \"times_seen\": 3.0}, {\"site\": 988, \"mutant\": \"C\", \"escape\": -0.014710208251851736, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -2.2801, \"times_seen\": 7.0}, {\"site\": 988, \"mutant\": \"D\", \"escape\": -0.0001561522250820727, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -0.113, \"times_seen\": 2.0}, {\"site\": 988, \"mutant\": \"F\", \"escape\": -0.07282906634974758, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -0.6941, \"times_seen\": 22.0}, {\"site\": 988, \"mutant\": \"I\", \"escape\": -0.05446843427695193, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -0.3699, \"times_seen\": 12.0}, {\"site\": 988, \"mutant\": \"L\", \"escape\": -0.008207714233182235, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": -1.7365, \"times_seen\": 2.0}, {\"site\": 988, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"991\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -3.0082, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -0.1337, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"H\", \"escape\": 0.024717788820995543, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 989, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -2.6481, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"L\", \"escape\": -0.004829972697145305, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -2.8081, \"times_seen\": 1.0}, {\"site\": 989, \"mutant\": \"P\", \"escape\": 0.01722228444111559, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -1.6191, \"times_seen\": 1.0}, {\"site\": 989, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"R\", \"escape\": -0.0016269214572548908, \"epitope\": \"epitope 1\", \"reference_site\": \"992\", \"functional effect\": -2.3991, \"times_seen\": 2.0}, {\"site\": 990, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 990, \"mutant\": \"L\", \"escape\": -0.007411133436241259, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": -0.2947, \"times_seen\": 8.0}, {\"site\": 990, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": -0.9604, \"times_seen\": null}, {\"site\": 990, \"mutant\": \"S\", \"escape\": -0.00367432911851635, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": -1.1686, \"times_seen\": 1.0}, {\"site\": 990, \"mutant\": \"T\", \"escape\": 8.433546989344227e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": 0.3956, \"times_seen\": 1.0}, {\"site\": 990, \"mutant\": \"V\", \"escape\": -0.025899805133653895, \"epitope\": \"epitope 1\", \"reference_site\": \"993\", \"functional effect\": 0.2884, \"times_seen\": 22.0}, {\"site\": 991, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 991, \"mutant\": \"E\", \"escape\": 0.018730195119602947, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.5788, \"times_seen\": 4.0}, {\"site\": 991, \"mutant\": \"F\", \"escape\": 0.018428220701600738, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.2389, \"times_seen\": 9.0}, {\"site\": 991, \"mutant\": \"G\", \"escape\": 0.1097014689530723, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.566, \"times_seen\": 8.0}, {\"site\": 991, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -3.0081, \"times_seen\": null}, {\"site\": 991, \"mutant\": \"N\", \"escape\": -0.01495687425015979, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.6505, \"times_seen\": 5.0}, {\"site\": 991, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -3.2113, \"times_seen\": null}, {\"site\": 991, \"mutant\": \"Y\", \"escape\": -0.0020001274122104936, \"epitope\": \"epitope 1\", \"reference_site\": \"994\", \"functional effect\": -2.8487, \"times_seen\": 1.0}, {\"site\": 992, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 992, \"mutant\": \"G\", \"escape\": -0.0035669512226676344, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.973, \"times_seen\": 9.0}, {\"site\": 992, \"mutant\": \"H\", \"escape\": -0.025490938346859355, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.282, \"times_seen\": 8.0}, {\"site\": 992, \"mutant\": \"I\", \"escape\": -0.00564455409569399, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.4317, \"times_seen\": 2.0}, {\"site\": 992, \"mutant\": \"K\", \"escape\": -0.008405933919943698, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.8796, \"times_seen\": 20.0}, {\"site\": 992, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 992, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -3.0258, \"times_seen\": null}, {\"site\": 992, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"995\", \"functional effect\": -2.9769, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"M\", \"escape\": 0.01613818547186592, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.7368, \"times_seen\": 6.0}, {\"site\": 993, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.9947, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.71, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"R\", \"escape\": -0.005709046729309671, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.6411, \"times_seen\": 2.0}, {\"site\": 993, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.9676, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"996\", \"functional effect\": -2.3938, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -1.7069, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -2.0252, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"T\", \"escape\": -0.0027023396304565414, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -2.9663, \"times_seen\": 1.0}, {\"site\": 994, \"mutant\": \"V\", \"escape\": -0.007010843968500996, \"epitope\": \"epitope 1\", \"reference_site\": \"997\", \"functional effect\": -0.4513, \"times_seen\": 6.0}, {\"site\": 995, \"mutant\": \"A\", \"escape\": -0.012440454552110066, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -0.2182, \"times_seen\": 5.0}, {\"site\": 995, \"mutant\": \"G\", \"escape\": 0.012130659179406896, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -0.5475, \"times_seen\": 4.0}, {\"site\": 995, \"mutant\": \"I\", \"escape\": 0.3819342359259051, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -0.1864, \"times_seen\": 58.0}, {\"site\": 995, \"mutant\": \"K\", \"escape\": 0.002731220871313012, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": -2.9961, \"times_seen\": 5.0}, {\"site\": 995, \"mutant\": \"S\", \"escape\": -0.022716849332639934, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": 0.2187, \"times_seen\": 8.0}, {\"site\": 995, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"998\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"C\", \"escape\": -0.004324178925137691, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.0619, \"times_seen\": 16.0}, {\"site\": 996, \"mutant\": \"D\", \"escape\": 0.027448053796700327, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.9368, \"times_seen\": 14.0}, {\"site\": 996, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.3833, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.312, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"S\", \"escape\": 0.010639079696478461, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -1.7115, \"times_seen\": 14.0}, {\"site\": 996, \"mutant\": \"V\", \"escape\": -0.00583506701445483, \"epitope\": \"epitope 1\", \"reference_site\": \"999\", \"functional effect\": -2.3977, \"times_seen\": 1.0}, {\"site\": 997, \"mutant\": \"G\", \"escape\": 0.00020002253620472697, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.1814, \"times_seen\": 1.0}, {\"site\": 997, \"mutant\": \"H\", \"escape\": -0.0054114550911450445, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.3084, \"times_seen\": 3.0}, {\"site\": 997, \"mutant\": \"I\", \"escape\": -0.008207045164053886, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.6788, \"times_seen\": 2.0}, {\"site\": 997, \"mutant\": \"K\", \"escape\": 0.05730592179365071, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.9436, \"times_seen\": 3.0}, {\"site\": 997, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 997, \"mutant\": \"S\", \"escape\": -0.0010846576769855537, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.8379, \"times_seen\": 1.0}, {\"site\": 997, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1000\", \"functional effect\": -2.983, \"times_seen\": null}, {\"site\": 998, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 998, \"mutant\": \"F\", \"escape\": -0.0012526689615159846, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.4962, \"times_seen\": 7.0}, {\"site\": 998, \"mutant\": \"H\", \"escape\": -0.0008733163447946104, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.0806, \"times_seen\": 1.0}, {\"site\": 998, \"mutant\": \"I\", \"escape\": 0.007367693746976584, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": 0.0572, \"times_seen\": 4.0}, {\"site\": 998, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 998, \"mutant\": \"P\", \"escape\": -0.04186476704967904, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.5626, \"times_seen\": 3.0}, {\"site\": 998, \"mutant\": \"Q\", \"escape\": 0.6025763741669302, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -2.0474, \"times_seen\": 4.0}, {\"site\": 998, \"mutant\": \"V\", \"escape\": -0.013279698914307175, \"epitope\": \"epitope 1\", \"reference_site\": \"1001\", \"functional effect\": -1.1479, \"times_seen\": 8.0}, {\"site\": 999, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -1.1754, \"times_seen\": null}, {\"site\": 999, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 999, \"mutant\": \"A\", \"escape\": 0.012301038294328418, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -1.4619, \"times_seen\": 2.0}, {\"site\": 999, \"mutant\": \"E\", \"escape\": 0.01139449506260744, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": 0.3082, \"times_seen\": 11.0}, {\"site\": 999, \"mutant\": \"H\", \"escape\": -0.009323763444376836, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -0.8236, \"times_seen\": 20.0}, {\"site\": 999, \"mutant\": \"K\", \"escape\": -0.14062760088150408, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.6935, \"times_seen\": 14.0}, {\"site\": 999, \"mutant\": \"L\", \"escape\": -0.03967870414025038, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.3498, \"times_seen\": 12.0}, {\"site\": 999, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 999, \"mutant\": \"R\", \"escape\": -0.005069077875240107, \"epitope\": \"epitope 1\", \"reference_site\": \"1002\", \"functional effect\": -2.6958, \"times_seen\": 3.0}, {\"site\": 1000, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 1000, \"mutant\": \"D\", \"escape\": 0.034233172532402385, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -2.9328, \"times_seen\": 2.0}, {\"site\": 1000, \"mutant\": \"F\", \"escape\": -0.029330175290710737, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -0.1891, \"times_seen\": 13.0}, {\"site\": 1000, \"mutant\": \"I\", \"escape\": 0.33277751645634795, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": 0.4444, \"times_seen\": 28.0}, {\"site\": 1000, \"mutant\": \"P\", \"escape\": -0.0013785212743924393, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -1.803, \"times_seen\": 1.0}, {\"site\": 1000, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1000, \"mutant\": \"T\", \"escape\": -0.010281892427054858, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -0.0835, \"times_seen\": 20.0}, {\"site\": 1000, \"mutant\": \"Y\", \"escape\": -0.006036789849673421, \"epitope\": \"epitope 1\", \"reference_site\": \"1003\", \"functional effect\": -0.1014, \"times_seen\": 2.0}, {\"site\": 1001, \"mutant\": \"F\", \"escape\": -0.0053078702416321745, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.8704, \"times_seen\": 3.0}, {\"site\": 1001, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.086, \"times_seen\": null}, {\"site\": 1001, \"mutant\": \"I\", \"escape\": -0.004865681589426395, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 1001, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1001, \"mutant\": \"P\", \"escape\": -0.08876556444977296, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -2.6499, \"times_seen\": 2.0}, {\"site\": 1001, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1004\", \"functional effect\": -3.137, \"times_seen\": null}, {\"site\": 1002, \"mutant\": \"*\", \"escape\": -0.0034064245027198878, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -2.2327, \"times_seen\": 1.0}, {\"site\": 1002, \"mutant\": \"H\", \"escape\": -0.006357655288031964, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -0.8476, \"times_seen\": 62.0}, {\"site\": 1002, \"mutant\": \"K\", \"escape\": -0.015832245680517488, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -2.1267, \"times_seen\": 11.0}, {\"site\": 1002, \"mutant\": \"L\", \"escape\": 0.0033557155133212414, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -1.2242, \"times_seen\": 20.0}, {\"site\": 1002, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1002, \"mutant\": \"R\", \"escape\": -0.00015320437666493778, \"epitope\": \"epitope 1\", \"reference_site\": \"1005\", \"functional effect\": -2.6955, \"times_seen\": 15.0}, {\"site\": 1003, \"mutant\": \"A\", \"escape\": -0.03842354162306694, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -0.0438, \"times_seen\": 21.0}, {\"site\": 1003, \"mutant\": \"I\", \"escape\": -1.2438749601686487, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -1.2634, \"times_seen\": 46.0}, {\"site\": 1003, \"mutant\": \"L\", \"escape\": -0.020415318914318185, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -2.1087, \"times_seen\": 5.0}, {\"site\": 1003, \"mutant\": \"N\", \"escape\": -0.01584236358336077, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": 0.2832, \"times_seen\": 3.0}, {\"site\": 1003, \"mutant\": \"S\", \"escape\": 0.0028591386854448743, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": 0.1799, \"times_seen\": 29.0}, {\"site\": 1003, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1003, \"mutant\": \"V\", \"escape\": -0.026400330710018256, \"epitope\": \"epitope 1\", \"reference_site\": \"1006\", \"functional effect\": -0.6323, \"times_seen\": 11.0}, {\"site\": 1004, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 1004, \"mutant\": \"C\", \"escape\": 0.010593149327095408, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -2.9151, \"times_seen\": 4.0}, {\"site\": 1004, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": 1.2037, \"times_seen\": null}, {\"site\": 1004, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": 0.4014, \"times_seen\": null}, {\"site\": 1004, \"mutant\": \"H\", \"escape\": -0.007931903386324098, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -2.7839, \"times_seen\": 4.0}, {\"site\": 1004, \"mutant\": \"N\", \"escape\": -0.0034866981434785796, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -2.6162, \"times_seen\": 1.0}, {\"site\": 1004, \"mutant\": \"S\", \"escape\": -0.0037254918007095053, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": -1.62, \"times_seen\": 1.0}, {\"site\": 1004, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1007\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1005, \"mutant\": \"A\", \"escape\": 0.010137806684427153, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -1.0404, \"times_seen\": 11.0}, {\"site\": 1005, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -3.1121, \"times_seen\": null}, {\"site\": 1005, \"mutant\": \"L\", \"escape\": 0.43724798292351846, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -1.0029, \"times_seen\": 11.0}, {\"site\": 1005, \"mutant\": \"M\", \"escape\": -0.010345035226028636, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -1.1313, \"times_seen\": 6.0}, {\"site\": 1005, \"mutant\": \"R\", \"escape\": 0.001073770383701767, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": -2.9835, \"times_seen\": 1.0}, {\"site\": 1005, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1008\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1006, \"mutant\": \"A\", \"escape\": -0.04340414309848395, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -2.336, \"times_seen\": 6.0}, {\"site\": 1006, \"mutant\": \"H\", \"escape\": 0.0155846262948527, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -1.0774, \"times_seen\": 19.0}, {\"site\": 1006, \"mutant\": \"I\", \"escape\": 0.006320246684118187, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -0.1907, \"times_seen\": 75.0}, {\"site\": 1006, \"mutant\": \"K\", \"escape\": -0.0049120569923488434, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -3.0194, \"times_seen\": 1.0}, {\"site\": 1006, \"mutant\": \"N\", \"escape\": -0.6654582678524503, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -1.5244, \"times_seen\": 21.0}, {\"site\": 1006, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -2.8706, \"times_seen\": null}, {\"site\": 1006, \"mutant\": \"S\", \"escape\": 0.030567802745087986, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -2.2375, \"times_seen\": 7.0}, {\"site\": 1006, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1006, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1009\", \"functional effect\": -3.2055, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -2.956, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.9976, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"K\", \"escape\": -0.02288663494267061, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.0605, \"times_seen\": 26.0}, {\"site\": 1007, \"mutant\": \"L\", \"escape\": -0.012247435581703468, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.3591, \"times_seen\": 8.0}, {\"site\": 1007, \"mutant\": \"M\", \"escape\": 0.04622069605573262, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.2318, \"times_seen\": 19.0}, {\"site\": 1007, \"mutant\": \"N\", \"escape\": -0.006029837751834202, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": -0.1312, \"times_seen\": 38.0}, {\"site\": 1007, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1010\", \"functional effect\": 0.0937, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -2.674, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -1.6132, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"H\", \"escape\": -0.1725227725797741, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.0277, \"times_seen\": 29.0}, {\"site\": 1008, \"mutant\": \"K\", \"escape\": -0.04510602661146809, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -1.6652, \"times_seen\": 15.0}, {\"site\": 1008, \"mutant\": \"L\", \"escape\": -0.015358330224123789, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.8592, \"times_seen\": 25.0}, {\"site\": 1008, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"R\", \"escape\": -0.012663008786168257, \"epitope\": \"epitope 1\", \"reference_site\": \"1011\", \"functional effect\": -0.8773, \"times_seen\": 4.0}, {\"site\": 1009, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1009, \"mutant\": \"F\", \"escape\": -0.028523157885480373, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -0.9178, \"times_seen\": 13.0}, {\"site\": 1009, \"mutant\": \"H\", \"escape\": -0.005494990159561801, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -0.3205, \"times_seen\": 2.0}, {\"site\": 1009, \"mutant\": \"I\", \"escape\": 0.12139856545461601, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -2.4375, \"times_seen\": 5.0}, {\"site\": 1009, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1009, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -2.955, \"times_seen\": null}, {\"site\": 1009, \"mutant\": \"R\", \"escape\": -0.005520255404552154, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1009, \"mutant\": \"S\", \"escape\": -0.017324073479307592, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 1009, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1012\", \"functional effect\": -2.4856, \"times_seen\": null}, {\"site\": 1010, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1010, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1010, \"mutant\": \"L\", \"escape\": -0.011659727677687434, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -0.6953, \"times_seen\": 7.0}, {\"site\": 1010, \"mutant\": \"M\", \"escape\": -0.00023576024948363281, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -0.9232, \"times_seen\": 2.0}, {\"site\": 1010, \"mutant\": \"N\", \"escape\": 0.03738628484550515, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -2.0467, \"times_seen\": 12.0}, {\"site\": 1010, \"mutant\": \"S\", \"escape\": 1.251424645261328, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -1.7187, \"times_seen\": 17.0}, {\"site\": 1010, \"mutant\": \"T\", \"escape\": 0.0030078857532579205, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -1.9471, \"times_seen\": 1.0}, {\"site\": 1010, \"mutant\": \"V\", \"escape\": -0.043656958834007956, \"epitope\": \"epitope 1\", \"reference_site\": \"1013\", \"functional effect\": -2.111, \"times_seen\": 4.0}, {\"site\": 1011, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1011, \"mutant\": \"G\", \"escape\": -0.10878432789295445, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -1.1865, \"times_seen\": 41.0}, {\"site\": 1011, \"mutant\": \"I\", \"escape\": -0.006580547171151645, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.8212, \"times_seen\": 18.0}, {\"site\": 1011, \"mutant\": \"K\", \"escape\": -0.013392851761980499, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": 0.4444, \"times_seen\": 71.0}, {\"site\": 1011, \"mutant\": \"M\", \"escape\": 0.006519839640623804, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.7817, \"times_seen\": 13.0}, {\"site\": 1011, \"mutant\": \"N\", \"escape\": -0.010447828896355177, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.9301, \"times_seen\": 7.0}, {\"site\": 1011, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1011, \"mutant\": \"S\", \"escape\": 0.000731763939070923, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.6521, \"times_seen\": 19.0}, {\"site\": 1011, \"mutant\": \"T\", \"escape\": -0.0763039554687492, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.1905, \"times_seen\": 38.0}, {\"site\": 1011, \"mutant\": \"W\", \"escape\": -0.006218835599739435, \"epitope\": \"epitope 1\", \"reference_site\": \"1014\", \"functional effect\": -0.8081, \"times_seen\": 3.0}, {\"site\": 1012, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1012, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1012, \"mutant\": \"D\", \"escape\": 0.02140558465930622, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -3.0886, \"times_seen\": 2.0}, {\"site\": 1012, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -0.4353, \"times_seen\": null}, {\"site\": 1012, \"mutant\": \"Q\", \"escape\": -0.016221835142112683, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -2.2673, \"times_seen\": 5.0}, {\"site\": 1012, \"mutant\": \"S\", \"escape\": 0.015397036588140582, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -0.2662, \"times_seen\": 34.0}, {\"site\": 1012, \"mutant\": \"T\", \"escape\": -0.0010645834507393612, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -2.0108, \"times_seen\": 7.0}, {\"site\": 1012, \"mutant\": \"V\", \"escape\": -0.014947834289548349, \"epitope\": \"epitope 1\", \"reference_site\": \"1015\", \"functional effect\": -2.7786, \"times_seen\": 5.0}, {\"site\": 1013, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -3.0364, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"G\", \"escape\": 0.0027443901337075955, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -1.9172, \"times_seen\": 1.0}, {\"site\": 1013, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.2801, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"L\", \"escape\": 0.011539800392446016, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -0.5694, \"times_seen\": 4.0}, {\"site\": 1013, \"mutant\": \"Q\", \"escape\": 0.0161832166667087, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": -0.1187, \"times_seen\": 11.0}, {\"site\": 1013, \"mutant\": \"S\", \"escape\": -0.10991608996186959, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.1466, \"times_seen\": 56.0}, {\"site\": 1013, \"mutant\": \"T\", \"escape\": 0.11660395482292965, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.4444, \"times_seen\": 145.0}, {\"site\": 1013, \"mutant\": \"V\", \"escape\": 0.03004204558864486, \"epitope\": \"epitope 1\", \"reference_site\": \"1016\", \"functional effect\": 0.3904, \"times_seen\": 64.0}, {\"site\": 1014, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.7502, \"times_seen\": null}, {\"site\": 1014, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1014, \"mutant\": \"D\", \"escape\": -0.17578357131591502, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.3865, \"times_seen\": 15.0}, {\"site\": 1014, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1014, \"mutant\": \"G\", \"escape\": -0.02905142975477651, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.2148, \"times_seen\": 5.0}, {\"site\": 1014, \"mutant\": \"K\", \"escape\": -0.14881482149630462, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.3651, \"times_seen\": 40.0}, {\"site\": 1014, \"mutant\": \"Q\", \"escape\": 0.005069517076738397, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1014, \"mutant\": \"V\", \"escape\": -0.0048691145935880805, \"epitope\": \"epitope 1\", \"reference_site\": \"1017\", \"functional effect\": -0.3501, \"times_seen\": 1.0}, {\"site\": 1015, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1015, \"mutant\": \"F\", \"escape\": -0.04495469692283294, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -1.9964, \"times_seen\": 16.0}, {\"site\": 1015, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1015, \"mutant\": \"L\", \"escape\": -0.06559703320006464, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -1.319, \"times_seen\": 22.0}, {\"site\": 1015, \"mutant\": \"M\", \"escape\": -0.057989376790191983, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -0.0369, \"times_seen\": 50.0}, {\"site\": 1015, \"mutant\": \"S\", \"escape\": -0.0062499512679190135, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 1015, \"mutant\": \"T\", \"escape\": -0.0029933152345995636, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -1.1885, \"times_seen\": 1.0}, {\"site\": 1015, \"mutant\": \"V\", \"escape\": 0.27134384775839643, \"epitope\": \"epitope 1\", \"reference_site\": \"1018\", \"functional effect\": -0.4457, \"times_seen\": 81.0}, {\"site\": 1016, \"mutant\": \"E\", \"escape\": -0.010348462968729384, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -2.4929, \"times_seen\": 1.0}, {\"site\": 1016, \"mutant\": \"G\", \"escape\": -1.7243517738761305, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -1.5594, \"times_seen\": 21.0}, {\"site\": 1016, \"mutant\": \"K\", \"escape\": -0.006987024946566747, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -0.6401, \"times_seen\": 29.0}, {\"site\": 1016, \"mutant\": \"M\", \"escape\": -0.012839565810737596, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -2.7786, \"times_seen\": 3.0}, {\"site\": 1016, \"mutant\": \"Q\", \"escape\": -0.020146223440478533, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -1.9902, \"times_seen\": 4.0}, {\"site\": 1016, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1016, \"mutant\": \"S\", \"escape\": -0.023752072842126108, \"epitope\": \"epitope 1\", \"reference_site\": \"1019\", \"functional effect\": -1.9743, \"times_seen\": 1.0}, {\"site\": 1017, \"mutant\": \"*\", \"escape\": -0.004425102977024563, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -2.9948, \"times_seen\": 1.0}, {\"site\": 1017, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1017, \"mutant\": \"C\", \"escape\": 0.007793035319158351, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6982, \"times_seen\": 17.0}, {\"site\": 1017, \"mutant\": \"D\", \"escape\": 0.053548018063783745, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.958, \"times_seen\": 28.0}, {\"site\": 1017, \"mutant\": \"E\", \"escape\": 0.021230001954850853, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -1.0272, \"times_seen\": 40.0}, {\"site\": 1017, \"mutant\": \"F\", \"escape\": -0.17771786211765345, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.2906, \"times_seen\": 12.0}, {\"site\": 1017, \"mutant\": \"G\", \"escape\": -0.08267247034416149, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.8455, \"times_seen\": 81.0}, {\"site\": 1017, \"mutant\": \"H\", \"escape\": -0.027923584960288454, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -1.6341, \"times_seen\": 13.0}, {\"site\": 1017, \"mutant\": \"I\", \"escape\": -0.01205805844085462, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6665, \"times_seen\": 6.0}, {\"site\": 1017, \"mutant\": \"K\", \"escape\": -1.8442374244245867, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -1.8672, \"times_seen\": 18.0}, {\"site\": 1017, \"mutant\": \"L\", \"escape\": -0.0371098452625208, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -2.4464, \"times_seen\": 14.0}, {\"site\": 1017, \"mutant\": \"M\", \"escape\": -0.019199454439752576, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.9902, \"times_seen\": 15.0}, {\"site\": 1017, \"mutant\": \"N\", \"escape\": -0.026734917514085015, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6127, \"times_seen\": 11.0}, {\"site\": 1017, \"mutant\": \"P\", \"escape\": 0.005134175139995773, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -2.7603, \"times_seen\": 5.0}, {\"site\": 1017, \"mutant\": \"Q\", \"escape\": 0.48721001000469377, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.7244, \"times_seen\": 22.0}, {\"site\": 1017, \"mutant\": \"R\", \"escape\": -0.061424307555560026, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.4314, \"times_seen\": 74.0}, {\"site\": 1017, \"mutant\": \"S\", \"escape\": -0.37495824238355313, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.2797, \"times_seen\": 111.0}, {\"site\": 1017, \"mutant\": \"T\", \"escape\": -0.2442727577088389, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.3397, \"times_seen\": 101.0}, {\"site\": 1017, \"mutant\": \"V\", \"escape\": -0.19836589732240925, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.6024, \"times_seen\": 127.0}, {\"site\": 1017, \"mutant\": \"W\", \"escape\": -0.004999603454327712, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.2591, \"times_seen\": 19.0}, {\"site\": 1017, \"mutant\": \"Y\", \"escape\": -0.0314387076275989, \"epitope\": \"epitope 1\", \"reference_site\": \"1020\", \"functional effect\": -0.4778, \"times_seen\": 10.0}, {\"site\": 1018, \"mutant\": \"A\", \"escape\": -0.005265950011519683, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.9083, \"times_seen\": 1.0}, {\"site\": 1018, \"mutant\": \"C\", \"escape\": -0.031083829667538213, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.8606, \"times_seen\": 10.0}, {\"site\": 1018, \"mutant\": \"F\", \"escape\": -0.15450183295839673, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.9573, \"times_seen\": 27.0}, {\"site\": 1018, \"mutant\": \"L\", \"escape\": -0.009737039390064277, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.9223, \"times_seen\": 7.0}, {\"site\": 1018, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -1.9687, \"times_seen\": null}, {\"site\": 1018, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1018, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -1.5061, \"times_seen\": null}, {\"site\": 1018, \"mutant\": \"Y\", \"escape\": -0.04666245561790079, \"epitope\": \"epitope 1\", \"reference_site\": \"1021\", \"functional effect\": -0.5607, \"times_seen\": 20.0}, {\"site\": 1019, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"D\", \"escape\": 0.01868663876282431, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.8753, \"times_seen\": 1.0}, {\"site\": 1019, \"mutant\": \"E\", \"escape\": -0.015124483625895243, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.4657, \"times_seen\": 6.0}, {\"site\": 1019, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"L\", \"escape\": 0.008897030428185147, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.9181, \"times_seen\": 1.0}, {\"site\": 1019, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -1.672, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.958, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"S\", \"escape\": -0.01607650210892194, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -0.8362, \"times_seen\": 34.0}, {\"site\": 1019, \"mutant\": \"T\", \"escape\": -0.008126070057946883, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.3735, \"times_seen\": 9.0}, {\"site\": 1019, \"mutant\": \"V\", \"escape\": 0.022113047935206197, \"epitope\": \"epitope 1\", \"reference_site\": \"1022\", \"functional effect\": -2.7325, \"times_seen\": 2.0}, {\"site\": 1020, \"mutant\": \"D\", \"escape\": 0.028791917606322208, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": -1.4309, \"times_seen\": 27.0}, {\"site\": 1020, \"mutant\": \"H\", \"escape\": -0.016996510157905445, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.1589, \"times_seen\": 29.0}, {\"site\": 1020, \"mutant\": \"I\", \"escape\": 0.00044695733993965303, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1020, \"mutant\": \"K\", \"escape\": 0.9210898074477465, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.0756, \"times_seen\": 79.0}, {\"site\": 1020, \"mutant\": \"L\", \"escape\": -0.12356203422524993, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.4444, \"times_seen\": 16.0}, {\"site\": 1020, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1020, \"mutant\": \"S\", \"escape\": 0.12666317009275863, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": -0.5625, \"times_seen\": 83.0}, {\"site\": 1020, \"mutant\": \"T\", \"escape\": -0.13052674597781638, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.031, \"times_seen\": 63.0}, {\"site\": 1020, \"mutant\": \"Y\", \"escape\": -0.33274978937438326, \"epitope\": \"epitope 1\", \"reference_site\": \"1023\", \"functional effect\": 0.3044, \"times_seen\": 54.0}, {\"site\": 1021, \"mutant\": \"F\", \"escape\": -0.016180233004554855, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -2.1134, \"times_seen\": 8.0}, {\"site\": 1021, \"mutant\": \"I\", \"escape\": -0.013076677863266746, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -1.4723, \"times_seen\": 25.0}, {\"site\": 1021, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1021, \"mutant\": \"M\", \"escape\": 0.01110901918757886, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -1.4396, \"times_seen\": 23.0}, {\"site\": 1021, \"mutant\": \"P\", \"escape\": -0.01046464946666469, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -2.4232, \"times_seen\": 1.0}, {\"site\": 1021, \"mutant\": \"Q\", \"escape\": 0.0009210437882995209, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -1.5057, \"times_seen\": 1.0}, {\"site\": 1021, \"mutant\": \"R\", \"escape\": -0.07519548709749066, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -0.5949, \"times_seen\": 24.0}, {\"site\": 1021, \"mutant\": \"V\", \"escape\": -0.0025251016042835443, \"epitope\": \"epitope 1\", \"reference_site\": \"1024\", \"functional effect\": -2.3092, \"times_seen\": 1.0}, {\"site\": 1022, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.2784, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"G\", \"escape\": -0.015099146294693506, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -0.9721, \"times_seen\": 11.0}, {\"site\": 1022, \"mutant\": \"L\", \"escape\": 0.017551050395421406, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.9406, \"times_seen\": 1.0}, {\"site\": 1022, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -3.0015, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -0.7165, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"T\", \"escape\": -0.00685981805925573, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.8946, \"times_seen\": 2.0}, {\"site\": 1022, \"mutant\": \"V\", \"escape\": 0.006911947313454152, \"epitope\": \"epitope 1\", \"reference_site\": \"1025\", \"functional effect\": -2.7023, \"times_seen\": 8.0}, {\"site\": 1023, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.5221, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"G\", \"escape\": -0.007190210262789832, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -0.3951, \"times_seen\": 1.0}, {\"site\": 1023, \"mutant\": \"I\", \"escape\": -0.009234306054902056, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.9787, \"times_seen\": 2.0}, {\"site\": 1023, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.8854, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"S\", \"escape\": -0.012041211551480394, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -0.2546, \"times_seen\": 19.0}, {\"site\": 1023, \"mutant\": \"T\", \"escape\": 0.009683900871464805, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -1.8377, \"times_seen\": 25.0}, {\"site\": 1023, \"mutant\": \"V\", \"escape\": -0.4926966353666792, \"epitope\": \"epitope 1\", \"reference_site\": \"1026\", \"functional effect\": -2.9637, \"times_seen\": 6.0}, {\"site\": 1024, \"mutant\": \"*\", \"escape\": -0.015977782964536835, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.9022, \"times_seen\": 5.0}, {\"site\": 1024, \"mutant\": \"A\", \"escape\": -0.06644182063344532, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.9119, \"times_seen\": 85.0}, {\"site\": 1024, \"mutant\": \"C\", \"escape\": -0.045410010994644354, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.6409, \"times_seen\": 34.0}, {\"site\": 1024, \"mutant\": \"D\", \"escape\": -0.08393271655144471, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.5114, \"times_seen\": 35.0}, {\"site\": 1024, \"mutant\": \"E\", \"escape\": -0.03591009952395987, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.0087, \"times_seen\": 33.0}, {\"site\": 1024, \"mutant\": \"F\", \"escape\": 0.49278528669924354, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8598, \"times_seen\": 48.0}, {\"site\": 1024, \"mutant\": \"G\", \"escape\": -0.06028591626428995, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.9465, \"times_seen\": 35.0}, {\"site\": 1024, \"mutant\": \"H\", \"escape\": -0.10532389195011019, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8568, \"times_seen\": 38.0}, {\"site\": 1024, \"mutant\": \"I\", \"escape\": 0.7865151495824302, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.4041, \"times_seen\": 54.0}, {\"site\": 1024, \"mutant\": \"K\", \"escape\": -0.00848800494664083, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.8558, \"times_seen\": 10.0}, {\"site\": 1024, \"mutant\": \"L\", \"escape\": -0.14823417658659144, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.0517, \"times_seen\": 144.0}, {\"site\": 1024, \"mutant\": \"M\", \"escape\": -0.021665296375842535, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.425, \"times_seen\": 43.0}, {\"site\": 1024, \"mutant\": \"N\", \"escape\": -0.2543636149110229, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -1.7085, \"times_seen\": 58.0}, {\"site\": 1024, \"mutant\": \"P\", \"escape\": 0.003121395263011561, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.5785, \"times_seen\": 10.0}, {\"site\": 1024, \"mutant\": \"Q\", \"escape\": -0.008174246596980014, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 1024, \"mutant\": \"R\", \"escape\": 0.04331590442039331, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8558, \"times_seen\": 117.0}, {\"site\": 1024, \"mutant\": \"S\", \"escape\": -1.467252867822322, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -0.8175, \"times_seen\": 180.0}, {\"site\": 1024, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1024, \"mutant\": \"V\", \"escape\": -0.019463992712587676, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.3363, \"times_seen\": 33.0}, {\"site\": 1024, \"mutant\": \"W\", \"escape\": 0.007232086895739298, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.0872, \"times_seen\": 8.0}, {\"site\": 1024, \"mutant\": \"Y\", \"escape\": 0.002568616928446348, \"epitope\": \"epitope 1\", \"reference_site\": \"1027\", \"functional effect\": -2.6245, \"times_seen\": 12.0}, {\"site\": 1025, \"mutant\": \"E\", \"escape\": -0.013078204643354309, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -0.1676, \"times_seen\": 1.0}, {\"site\": 1025, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1025, \"mutant\": \"L\", \"escape\": -0.7664551968723045, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -2.9637, \"times_seen\": 4.0}, {\"site\": 1025, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -1.3488, \"times_seen\": null}, {\"site\": 1025, \"mutant\": \"N\", \"escape\": -0.020428702811084328, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -2.6429, \"times_seen\": 4.0}, {\"site\": 1025, \"mutant\": \"R\", \"escape\": -0.023604753751759137, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -2.3767, \"times_seen\": 6.0}, {\"site\": 1025, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1028\", \"functional effect\": -1.1122, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"C\", \"escape\": -0.009279879663506916, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.451, \"times_seen\": 1.0}, {\"site\": 1026, \"mutant\": \"I\", \"escape\": -1.0876577089680273, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -1.349, \"times_seen\": 47.0}, {\"site\": 1026, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"L\", \"escape\": -0.00060281005670202, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.596, \"times_seen\": 2.0}, {\"site\": 1026, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"R\", \"escape\": -0.008060795945774765, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.2197, \"times_seen\": 1.0}, {\"site\": 1026, \"mutant\": \"T\", \"escape\": -0.009216045411735761, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -2.5108, \"times_seen\": 1.0}, {\"site\": 1026, \"mutant\": \"V\", \"escape\": 0.026903529269412748, \"epitope\": \"epitope 1\", \"reference_site\": \"1029\", \"functional effect\": -1.3142, \"times_seen\": 25.0}, {\"site\": 1027, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"A\", \"escape\": 0.0013528449529949618, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -0.1609, \"times_seen\": 17.0}, {\"site\": 1027, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.028, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"G\", \"escape\": 0.0298627184908096, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.5245, \"times_seen\": 4.0}, {\"site\": 1027, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -3.1432, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"L\", \"escape\": 0.04760345874039657, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.9561, \"times_seen\": 3.0}, {\"site\": 1027, \"mutant\": \"N\", \"escape\": 0.0006157593882977881, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.4774, \"times_seen\": 1.0}, {\"site\": 1027, \"mutant\": \"Q\", \"escape\": -0.0015094867710560558, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -2.6183, \"times_seen\": 1.0}, {\"site\": 1027, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": -1.0065, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1030\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"*\", \"escape\": 0.013211059438810341, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.7814, \"times_seen\": 1.0}, {\"site\": 1028, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9215, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -3.0479, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"K\", \"escape\": 0.7730971849469576, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9297, \"times_seen\": 11.0}, {\"site\": 1028, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"S\", \"escape\": 0.01390588871586221, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.8256, \"times_seen\": 1.0}, {\"site\": 1028, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1031\", \"functional effect\": -2.9863, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.7992, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9457, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -3.2569, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -3.0016, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"V\", \"escape\": 0.029958541491156367, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9152, \"times_seen\": 1.0}, {\"site\": 1029, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1032\", \"functional effect\": -2.9672, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"A\", \"escape\": 0.01586333493487981, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -1.4429, \"times_seen\": 9.0}, {\"site\": 1030, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.6421, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"L\", \"escape\": -0.005508952459875598, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.6888, \"times_seen\": 1.0}, {\"site\": 1030, \"mutant\": \"M\", \"escape\": -0.0067725794378070015, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.434, \"times_seen\": 2.0}, {\"site\": 1030, \"mutant\": \"T\", \"escape\": -0.001297560685854177, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.0594, \"times_seen\": 1.0}, {\"site\": 1030, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"Y\", \"escape\": -0.007122245564225854, \"epitope\": \"epitope 1\", \"reference_site\": \"1033\", \"functional effect\": -2.5961, \"times_seen\": 2.0}, {\"site\": 1031, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"F\", \"escape\": -2.7428776917905804, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -1.0692, \"times_seen\": 6.0}, {\"site\": 1031, \"mutant\": \"I\", \"escape\": -0.005075245381618159, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -1.2398, \"times_seen\": 15.0}, {\"site\": 1031, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"M\", \"escape\": -0.031108166305156674, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": 0.3887, \"times_seen\": 4.0}, {\"site\": 1031, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -2.9507, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -0.8952, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"R\", \"escape\": -0.0028183691080768025, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": 0.3651, \"times_seen\": 30.0}, {\"site\": 1031, \"mutant\": \"V\", \"escape\": -0.015769846249802245, \"epitope\": \"epitope 1\", \"reference_site\": \"1034\", \"functional effect\": -0.9591, \"times_seen\": 1.0}, {\"site\": 1032, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.7367, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"D\", \"escape\": 0.01081396143237059, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.6997, \"times_seen\": 3.0}, {\"site\": 1032, \"mutant\": \"E\", \"escape\": -0.0008691842549469873, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.4806, \"times_seen\": 1.0}, {\"site\": 1032, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.744, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"R\", \"escape\": -0.010216171342187916, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.7178, \"times_seen\": 5.0}, {\"site\": 1032, \"mutant\": \"V\", \"escape\": -0.017344833458937264, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.6825, \"times_seen\": 7.0}, {\"site\": 1032, \"mutant\": \"W\", \"escape\": -0.00609738418768747, \"epitope\": \"epitope 1\", \"reference_site\": \"1035\", \"functional effect\": -2.465, \"times_seen\": 5.0}, {\"site\": 1033, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -1.6874, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"N\", \"escape\": -0.010414475188681915, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -2.558, \"times_seen\": 5.0}, {\"site\": 1033, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"R\", \"escape\": -0.0034531974996833844, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -2.933, \"times_seen\": 1.0}, {\"site\": 1033, \"mutant\": \"T\", \"escape\": -0.007426749357504419, \"epitope\": \"epitope 1\", \"reference_site\": \"1036\", \"functional effect\": -2.6751, \"times_seen\": 1.0}, {\"site\": 1034, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1034, \"mutant\": \"C\", \"escape\": -0.005695846665110179, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -0.7186, \"times_seen\": 1.0}, {\"site\": 1034, \"mutant\": \"G\", \"escape\": 0.017985182591447497, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -1.4326, \"times_seen\": 2.0}, {\"site\": 1034, \"mutant\": \"I\", \"escape\": -0.004300632220657742, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.7668, \"times_seen\": 6.0}, {\"site\": 1034, \"mutant\": \"L\", \"escape\": -0.006241917809917036, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.3881, \"times_seen\": 2.0}, {\"site\": 1034, \"mutant\": \"N\", \"escape\": -0.038864338134293755, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -0.5421, \"times_seen\": 18.0}, {\"site\": 1034, \"mutant\": \"Q\", \"escape\": -0.002903245765189765, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.4226, \"times_seen\": 1.0}, {\"site\": 1034, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": -2.9471, \"times_seen\": null}, {\"site\": 1034, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1037\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"E\", \"escape\": 0.011781225161750678, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -1.0333, \"times_seen\": 27.0}, {\"site\": 1035, \"mutant\": \"G\", \"escape\": 0.0007148197584280052, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -1.7715, \"times_seen\": 1.0}, {\"site\": 1035, \"mutant\": \"I\", \"escape\": 0.06194878230898359, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.3826, \"times_seen\": 14.0}, {\"site\": 1035, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.1395, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"N\", \"escape\": 0.8016732177101461, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.3265, \"times_seen\": 20.0}, {\"site\": 1035, \"mutant\": \"Q\", \"escape\": 0.0003706136085063276, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.0722, \"times_seen\": 25.0}, {\"site\": 1035, \"mutant\": \"R\", \"escape\": 0.16640192988003838, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": 0.2803, \"times_seen\": 49.0}, {\"site\": 1035, \"mutant\": \"T\", \"escape\": 0.023066453133877344, \"epitope\": \"epitope 1\", \"reference_site\": \"1038\", \"functional effect\": -0.1467, \"times_seen\": 12.0}, {\"site\": 1036, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"E\", \"escape\": -0.003394100025157199, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -3.0763, \"times_seen\": 1.0}, {\"site\": 1036, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.5103, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"K\", \"escape\": 0.0008587799692946838, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.479, \"times_seen\": 2.0}, {\"site\": 1036, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"S\", \"escape\": -0.0023651571629119323, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -2.9133, \"times_seen\": 1.0}, {\"site\": 1036, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1039\", \"functional effect\": -3.1583, \"times_seen\": null}, {\"site\": 1037, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1037, \"mutant\": \"A\", \"escape\": -0.04569686028172526, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": 0.0238, \"times_seen\": 22.0}, {\"site\": 1037, \"mutant\": \"F\", \"escape\": -0.06945845702060396, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -0.9927, \"times_seen\": 22.0}, {\"site\": 1037, \"mutant\": \"I\", \"escape\": -0.02673699390273836, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -2.6141, \"times_seen\": 2.0}, {\"site\": 1037, \"mutant\": \"L\", \"escape\": -0.015014968507948862, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -2.0361, \"times_seen\": 5.0}, {\"site\": 1037, \"mutant\": \"M\", \"escape\": 0.01946934788403697, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -2.0321, \"times_seen\": 9.0}, {\"site\": 1037, \"mutant\": \"S\", \"escape\": 0.03212860454460829, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": -0.3684, \"times_seen\": 22.0}, {\"site\": 1037, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1040\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1038, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1038, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1038, \"mutant\": \"E\", \"escape\": 0.006446314642004409, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.3271, \"times_seen\": 16.0}, {\"site\": 1038, \"mutant\": \"G\", \"escape\": -0.02296919554278135, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.9511, \"times_seen\": 126.0}, {\"site\": 1038, \"mutant\": \"I\", \"escape\": -0.0009469904605294927, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -2.4891, \"times_seen\": 1.0}, {\"site\": 1038, \"mutant\": \"N\", \"escape\": 0.01911458450900886, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -2.072, \"times_seen\": 29.0}, {\"site\": 1038, \"mutant\": \"Y\", \"escape\": 0.01856761588028312, \"epitope\": \"epitope 1\", \"reference_site\": \"1041\", \"functional effect\": -0.8159, \"times_seen\": 1.0}, {\"site\": 1039, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.7063, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"L\", \"escape\": -0.01960743561872607, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -0.7176, \"times_seen\": 16.0}, {\"site\": 1039, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.9171, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1042\", \"functional effect\": -2.3389, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.9823, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -3.0004, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -0.4876, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"L\", \"escape\": -0.0034762818725632832, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.6105, \"times_seen\": 3.0}, {\"site\": 1040, \"mutant\": \"R\", \"escape\": -0.007042457313764116, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -1.6803, \"times_seen\": 6.0}, {\"site\": 1040, \"mutant\": \"S\", \"escape\": -0.002698097220217648, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -1.0532, \"times_seen\": 1.0}, {\"site\": 1040, \"mutant\": \"V\", \"escape\": 0.023115987453670106, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.4504, \"times_seen\": 5.0}, {\"site\": 1040, \"mutant\": \"Y\", \"escape\": -0.0019759428114362746, \"epitope\": \"epitope 1\", \"reference_site\": \"1043\", \"functional effect\": -2.8414, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -3.0044, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"C\", \"escape\": -0.009402093232563477, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -1.4106, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"D\", \"escape\": -0.8604002489860294, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.8731, \"times_seen\": 4.0}, {\"site\": 1041, \"mutant\": \"E\", \"escape\": -0.010150940652882735, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.2404, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"V\", \"escape\": 0.01756962460712177, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.9256, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"W\", \"escape\": -0.028363533886277895, \"epitope\": \"epitope 1\", \"reference_site\": \"1044\", \"functional effect\": -2.7309, \"times_seen\": 8.0}, {\"site\": 1042, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1042, \"mutant\": \"E\", \"escape\": 0.040039508179731384, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.8822, \"times_seen\": 23.0}, {\"site\": 1042, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1042, \"mutant\": \"M\", \"escape\": 0.0388735585218474, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -2.2214, \"times_seen\": 10.0}, {\"site\": 1042, \"mutant\": \"N\", \"escape\": -0.11604547123633688, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.1793, \"times_seen\": 26.0}, {\"site\": 1042, \"mutant\": \"Q\", \"escape\": 0.1498688646679225, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.018, \"times_seen\": 15.0}, {\"site\": 1042, \"mutant\": \"R\", \"escape\": -0.028991115096781376, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": 0.1656, \"times_seen\": 52.0}, {\"site\": 1042, \"mutant\": \"T\", \"escape\": 0.05004753891592264, \"epitope\": \"epitope 1\", \"reference_site\": \"1045\", \"functional effect\": -1.3548, \"times_seen\": 10.0}, {\"site\": 1043, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1043, \"mutant\": \"A\", \"escape\": 0.03716605214553179, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -1.1822, \"times_seen\": 12.0}, {\"site\": 1043, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -1.1639, \"times_seen\": null}, {\"site\": 1043, \"mutant\": \"D\", \"escape\": -0.8734407897477693, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -2.8615, \"times_seen\": 4.0}, {\"site\": 1043, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1043, \"mutant\": \"S\", \"escape\": -0.019573801691206594, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -1.7674, \"times_seen\": 7.0}, {\"site\": 1043, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1046\", \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"*\", \"escape\": -0.005810908980202367, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -3.0069, \"times_seen\": 1.0}, {\"site\": 1044, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"C\", \"escape\": -0.03484604879578439, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.5979, \"times_seen\": 5.0}, {\"site\": 1044, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"F\", \"escape\": 0.05946058501200699, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.3915, \"times_seen\": 11.0}, {\"site\": 1044, \"mutant\": \"H\", \"escape\": 0.012536088004855705, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -2.6773, \"times_seen\": 5.0}, {\"site\": 1044, \"mutant\": \"L\", \"escape\": -0.04517136282565728, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -0.3012, \"times_seen\": 10.0}, {\"site\": 1044, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": -3.3118, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1047\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.26, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.0083, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -2.8866, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"S\", \"escape\": -0.0033883589681908003, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.1124, \"times_seen\": 1.0}, {\"site\": 1045, \"mutant\": \"Y\", \"escape\": -0.0029000456399678005, \"epitope\": \"epitope 1\", \"reference_site\": \"1048\", \"functional effect\": -3.0457, \"times_seen\": 1.0}, {\"site\": 1046, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1046, \"mutant\": \"F\", \"escape\": -0.0059129551544895, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.8127, \"times_seen\": 2.0}, {\"site\": 1046, \"mutant\": \"I\", \"escape\": 0.008542147822304511, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.1582, \"times_seen\": 13.0}, {\"site\": 1046, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1046, \"mutant\": \"M\", \"escape\": -0.003934998540290754, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.3985, \"times_seen\": 1.0}, {\"site\": 1046, \"mutant\": \"P\", \"escape\": -0.00334184896898055, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.9313, \"times_seen\": 1.0}, {\"site\": 1046, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.3805, \"times_seen\": null}, {\"site\": 1046, \"mutant\": \"S\", \"escape\": -0.0038766669754682053, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.4874, \"times_seen\": 2.0}, {\"site\": 1046, \"mutant\": \"V\", \"escape\": 0.0061716517598473025, \"epitope\": \"epitope 1\", \"reference_site\": \"1049\", \"functional effect\": -2.5783, \"times_seen\": 6.0}, {\"site\": 1047, \"mutant\": \"I\", \"escape\": -0.06853242098739906, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -0.8474, \"times_seen\": 91.0}, {\"site\": 1047, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -2.7832, \"times_seen\": null}, {\"site\": 1047, \"mutant\": \"L\", \"escape\": -0.012435070260654008, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -0.1566, \"times_seen\": 32.0}, {\"site\": 1047, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1047, \"mutant\": \"T\", \"escape\": 0.01125845636373603, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -2.1339, \"times_seen\": 7.0}, {\"site\": 1047, \"mutant\": \"V\", \"escape\": -1.4185606736082783, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -1.9149, \"times_seen\": 19.0}, {\"site\": 1047, \"mutant\": \"Y\", \"escape\": -0.01970672536299648, \"epitope\": \"epitope 1\", \"reference_site\": \"1050\", \"functional effect\": -2.3353, \"times_seen\": 2.0}, {\"site\": 1048, \"mutant\": \"G\", \"escape\": 0.018932462434274475, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.1776, \"times_seen\": 2.0}, {\"site\": 1048, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 1048, \"mutant\": \"L\", \"escape\": -0.0022898005371414965, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.77, \"times_seen\": 1.0}, {\"site\": 1048, \"mutant\": \"N\", \"escape\": -0.006371387767430469, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.9548, \"times_seen\": 2.0}, {\"site\": 1048, \"mutant\": \"R\", \"escape\": -0.0028431697765150888, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.9464, \"times_seen\": 1.0}, {\"site\": 1048, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1048, \"mutant\": \"T\", \"escape\": -0.002756424812052194, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1048, \"mutant\": \"V\", \"escape\": 0.002219755372706191, \"epitope\": \"epitope 1\", \"reference_site\": \"1051\", \"functional effect\": -2.7313, \"times_seen\": 1.0}, {\"site\": 1049, \"mutant\": \"C\", \"escape\": 0.012993577351108402, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -2.9498, \"times_seen\": 1.0}, {\"site\": 1049, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1049, \"mutant\": \"I\", \"escape\": -0.018147473843369826, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -2.9411, \"times_seen\": 5.0}, {\"site\": 1049, \"mutant\": \"L\", \"escape\": -0.0015183641709033886, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -1.1545, \"times_seen\": 22.0}, {\"site\": 1049, \"mutant\": \"S\", \"escape\": -0.0036728195240710803, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -0.6482, \"times_seen\": 1.0}, {\"site\": 1049, \"mutant\": \"V\", \"escape\": -0.009801195023640602, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 1049, \"mutant\": \"Y\", \"escape\": -0.04318395730449104, \"epitope\": \"epitope 1\", \"reference_site\": \"1052\", \"functional effect\": -1.0543, \"times_seen\": 29.0}, {\"site\": 1051, \"mutant\": \"*\", \"escape\": 0.09952903061385941, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.4716, \"times_seen\": 2.0}, {\"site\": 1051, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.999, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.7168, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.9766, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"L\", \"escape\": 3.46515755071749, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -3.0239, \"times_seen\": 4.0}, {\"site\": 1051, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"R\", \"escape\": 0.12125346866539544, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.2702, \"times_seen\": 1.0}, {\"site\": 1051, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1054\", \"functional effect\": -2.5057, \"times_seen\": null}, {\"site\": 1052, \"mutant\": \"A\", \"escape\": -0.03738631198878299, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -0.0857, \"times_seen\": 16.0}, {\"site\": 1052, \"mutant\": \"C\", \"escape\": -0.0018432847481526032, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.9005, \"times_seen\": 1.0}, {\"site\": 1052, \"mutant\": \"F\", \"escape\": 0.016037451966223488, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.8457, \"times_seen\": 2.0}, {\"site\": 1052, \"mutant\": \"L\", \"escape\": 0.05465780961441756, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -2.3702, \"times_seen\": 11.0}, {\"site\": 1052, \"mutant\": \"P\", \"escape\": -0.004050786076029, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -2.4943, \"times_seen\": 1.0}, {\"site\": 1052, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1052, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1052, \"mutant\": \"V\", \"escape\": 5.721032602233222e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.7888, \"times_seen\": 9.0}, {\"site\": 1052, \"mutant\": \"Y\", \"escape\": 0.022780696542239017, \"epitope\": \"epitope 1\", \"reference_site\": \"1055\", \"functional effect\": -1.1067, \"times_seen\": 10.0}, {\"site\": 1053, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -3.1635, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -3.265, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"S\", \"escape\": 0.012131578498607314, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -2.8479, \"times_seen\": 1.0}, {\"site\": 1053, \"mutant\": \"T\", \"escape\": -0.0017679868937965782, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -2.9022, \"times_seen\": 3.0}, {\"site\": 1053, \"mutant\": \"V\", \"escape\": -0.7223223369049655, \"epitope\": \"epitope 1\", \"reference_site\": \"1056\", \"functional effect\": -1.5274, \"times_seen\": 41.0}, {\"site\": 1054, \"mutant\": \"H\", \"escape\": -0.002895912727233378, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.98, \"times_seen\": 1.0}, {\"site\": 1054, \"mutant\": \"L\", \"escape\": 0.12537800188629655, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.7923, \"times_seen\": 6.0}, {\"site\": 1054, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1054, \"mutant\": \"Q\", \"escape\": -0.006142827714243598, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.7854, \"times_seen\": 2.0}, {\"site\": 1054, \"mutant\": \"S\", \"escape\": 0.03382321229582998, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -0.7767, \"times_seen\": 1.0}, {\"site\": 1054, \"mutant\": \"T\", \"escape\": -0.0007425393535197909, \"epitope\": \"epitope 1\", \"reference_site\": \"1057\", \"functional effect\": -2.3737, \"times_seen\": 8.0}, {\"site\": 1055, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1055, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -1.911, \"times_seen\": null}, {\"site\": 1055, \"mutant\": \"N\", \"escape\": -0.016370014295935, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.3326, \"times_seen\": 21.0}, {\"site\": 1055, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.4864, \"times_seen\": null}, {\"site\": 1055, \"mutant\": \"R\", \"escape\": -0.04739007814804181, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.5183, \"times_seen\": 61.0}, {\"site\": 1055, \"mutant\": \"S\", \"escape\": 0.012667804081509484, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -0.5405, \"times_seen\": 16.0}, {\"site\": 1055, \"mutant\": \"Y\", \"escape\": -0.08283616843944826, \"epitope\": \"epitope 1\", \"reference_site\": \"1058\", \"functional effect\": -1.0804, \"times_seen\": 52.0}, {\"site\": 1056, \"mutant\": \"*\", \"escape\": -0.00039877750855326315, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.1962, \"times_seen\": 2.0}, {\"site\": 1056, \"mutant\": \"E\", \"escape\": -0.014451666749197843, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.5641, \"times_seen\": 5.0}, {\"site\": 1056, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1056, \"mutant\": \"L\", \"escape\": -0.00732258096825831, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.5162, \"times_seen\": 6.0}, {\"site\": 1056, \"mutant\": \"R\", \"escape\": 0.05094308018910275, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.4709, \"times_seen\": 5.0}, {\"site\": 1056, \"mutant\": \"V\", \"escape\": -0.002995338571352991, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.5775, \"times_seen\": 1.0}, {\"site\": 1056, \"mutant\": \"W\", \"escape\": 0.004462259410705659, \"epitope\": \"epitope 1\", \"reference_site\": \"1059\", \"functional effect\": -2.9473, \"times_seen\": 4.0}, {\"site\": 1057, \"mutant\": \"A\", \"escape\": -0.009518893061196637, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -0.8753, \"times_seen\": 11.0}, {\"site\": 1057, \"mutant\": \"C\", \"escape\": 0.02796456106977476, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -0.6008, \"times_seen\": 15.0}, {\"site\": 1057, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -2.9006, \"times_seen\": null}, {\"site\": 1057, \"mutant\": \"I\", \"escape\": -0.0072966920854520044, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -0.2763, \"times_seen\": 19.0}, {\"site\": 1057, \"mutant\": \"L\", \"escape\": 1.1849278920657815, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -2.1423, \"times_seen\": 20.0}, {\"site\": 1057, \"mutant\": \"M\", \"escape\": -0.008225604600483067, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": -2.6312, \"times_seen\": 4.0}, {\"site\": 1057, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1060\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1058, \"mutant\": \"A\", \"escape\": -0.01094349639425452, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.4204, \"times_seen\": 10.0}, {\"site\": 1058, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.3743, \"times_seen\": null}, {\"site\": 1058, \"mutant\": \"F\", \"escape\": -0.009977861858190903, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.3203, \"times_seen\": 9.0}, {\"site\": 1058, \"mutant\": \"I\", \"escape\": -0.02682889518389259, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -1.0395, \"times_seen\": 12.0}, {\"site\": 1058, \"mutant\": \"L\", \"escape\": 0.00011349034023502123, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": 0.0117, \"times_seen\": 3.0}, {\"site\": 1058, \"mutant\": \"M\", \"escape\": -0.001247432837640472, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -0.0322, \"times_seen\": 10.0}, {\"site\": 1058, \"mutant\": \"S\", \"escape\": -0.015587793849360206, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": -2.7374, \"times_seen\": 2.0}, {\"site\": 1058, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1061\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1059, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1059, \"mutant\": \"I\", \"escape\": 0.004200597130496127, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -2.5942, \"times_seen\": 1.0}, {\"site\": 1059, \"mutant\": \"L\", \"escape\": 0.5353323322034748, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -1.2258, \"times_seen\": 14.0}, {\"site\": 1059, \"mutant\": \"S\", \"escape\": 0.004653203521266659, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -2.8525, \"times_seen\": 4.0}, {\"site\": 1059, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -3.053, \"times_seen\": null}, {\"site\": 1059, \"mutant\": \"Y\", \"escape\": -0.008744231989344986, \"epitope\": \"epitope 1\", \"reference_site\": \"1062\", \"functional effect\": -0.6038, \"times_seen\": 2.0}, {\"site\": 1060, \"mutant\": \"*\", \"escape\": -0.006683664214824772, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6833, \"times_seen\": 3.0}, {\"site\": 1060, \"mutant\": \"A\", \"escape\": 0.015414902352633675, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.513, \"times_seen\": 10.0}, {\"site\": 1060, \"mutant\": \"C\", \"escape\": -0.009477448576729603, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5841, \"times_seen\": 9.0}, {\"site\": 1060, \"mutant\": \"D\", \"escape\": 0.030449590222654546, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.738, \"times_seen\": 6.0}, {\"site\": 1060, \"mutant\": \"E\", \"escape\": -0.014911282212022293, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.7019, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"F\", \"escape\": -0.022645339999513788, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -1.2671, \"times_seen\": 46.0}, {\"site\": 1060, \"mutant\": \"G\", \"escape\": 0.0006971313476710977, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5585, \"times_seen\": 18.0}, {\"site\": 1060, \"mutant\": \"H\", \"escape\": 0.009922840800144989, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5981, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"I\", \"escape\": -0.03880527462617965, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -1.4099, \"times_seen\": 31.0}, {\"site\": 1060, \"mutant\": \"K\", \"escape\": -0.013117350221405344, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6852, \"times_seen\": 4.0}, {\"site\": 1060, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1060, \"mutant\": \"M\", \"escape\": -0.016020743903673966, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -0.7638, \"times_seen\": 22.0}, {\"site\": 1060, \"mutant\": \"N\", \"escape\": -0.010355582284837904, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6918, \"times_seen\": 4.0}, {\"site\": 1060, \"mutant\": \"P\", \"escape\": 0.04304310011981243, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.6696, \"times_seen\": 14.0}, {\"site\": 1060, \"mutant\": \"Q\", \"escape\": -0.008049719601378288, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.8479, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"R\", \"escape\": 0.008050370651120832, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.7412, \"times_seen\": 16.0}, {\"site\": 1060, \"mutant\": \"S\", \"escape\": -0.02812710486164889, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.5558, \"times_seen\": 15.0}, {\"site\": 1060, \"mutant\": \"T\", \"escape\": 0.006120248579533529, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.7268, \"times_seen\": 7.0}, {\"site\": 1060, \"mutant\": \"V\", \"escape\": 0.05543118556637673, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -1.8064, \"times_seen\": 58.0}, {\"site\": 1060, \"mutant\": \"W\", \"escape\": 0.02487435827972674, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -2.3231, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"Y\", \"escape\": 0.016374056701897892, \"epitope\": \"epitope 1\", \"reference_site\": \"1063\", \"functional effect\": -3.0762, \"times_seen\": 3.0}, {\"site\": 1061, \"mutant\": \"A\", \"escape\": 0.0019129867037356535, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -3.0111, \"times_seen\": 1.0}, {\"site\": 1061, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.6745, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.4501, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -1.8627, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"R\", \"escape\": 0.04189516351143921, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.0417, \"times_seen\": 1.0}, {\"site\": 1061, \"mutant\": \"Y\", \"escape\": -0.004945280828758175, \"epitope\": \"epitope 1\", \"reference_site\": \"1064\", \"functional effect\": -2.1372, \"times_seen\": 3.0}, {\"site\": 1062, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -0.9906, \"times_seen\": null}, {\"site\": 1062, \"mutant\": \"A\", \"escape\": -0.05300709199669149, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -0.3229, \"times_seen\": 31.0}, {\"site\": 1062, \"mutant\": \"C\", \"escape\": 0.004957302875556718, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": 0.125, \"times_seen\": 8.0}, {\"site\": 1062, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -2.9248, \"times_seen\": null}, {\"site\": 1062, \"mutant\": \"L\", \"escape\": -0.8480104480358437, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": -0.6764, \"times_seen\": 90.0}, {\"site\": 1062, \"mutant\": \"M\", \"escape\": 0.5978137954990925, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": 0.4444, \"times_seen\": 47.0}, {\"site\": 1062, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1065\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1063, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1063, \"mutant\": \"A\", \"escape\": -0.03922433033865941, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -0.233, \"times_seen\": 22.0}, {\"site\": 1063, \"mutant\": \"D\", \"escape\": -0.07887788728580077, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -0.4897, \"times_seen\": 36.0}, {\"site\": 1063, \"mutant\": \"I\", \"escape\": -0.05027654454454054, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -1.4653, \"times_seen\": 29.0}, {\"site\": 1063, \"mutant\": \"N\", \"escape\": 0.20812921847334953, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": 0.2891, \"times_seen\": 104.0}, {\"site\": 1063, \"mutant\": \"P\", \"escape\": 0.0635705767035343, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": -2.9958, \"times_seen\": 4.0}, {\"site\": 1063, \"mutant\": \"S\", \"escape\": -0.2352266473226854, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": 0.2725, \"times_seen\": 44.0}, {\"site\": 1063, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1066\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -3.1347, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -1.8727, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -2.9832, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"F\", \"escape\": -1.8894952247522339, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -0.8799, \"times_seen\": 37.0}, {\"site\": 1064, \"mutant\": \"H\", \"escape\": -0.05156489050906405, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -2.6468, \"times_seen\": 4.0}, {\"site\": 1064, \"mutant\": \"L\", \"escape\": -0.03006736839494655, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -2.9939, \"times_seen\": 2.0}, {\"site\": 1064, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": -3.0924, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1067\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1065, \"mutant\": \"*\", \"escape\": -0.0020202166556833054, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.4287, \"times_seen\": 6.0}, {\"site\": 1065, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1065, \"mutant\": \"A\", \"escape\": -0.002332576458988107, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.1319, \"times_seen\": 30.0}, {\"site\": 1065, \"mutant\": \"C\", \"escape\": 0.10977220019206306, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.0246, \"times_seen\": 58.0}, {\"site\": 1065, \"mutant\": \"D\", \"escape\": 0.013097812162119074, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.55, \"times_seen\": 13.0}, {\"site\": 1065, \"mutant\": \"E\", \"escape\": 0.08342045456040575, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.4462, \"times_seen\": 16.0}, {\"site\": 1065, \"mutant\": \"F\", \"escape\": -0.011688216979536575, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.9872, \"times_seen\": 26.0}, {\"site\": 1065, \"mutant\": \"G\", \"escape\": -0.9279950727429921, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.5016, \"times_seen\": 11.0}, {\"site\": 1065, \"mutant\": \"H\", \"escape\": -0.019023269417125833, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.3264, \"times_seen\": 15.0}, {\"site\": 1065, \"mutant\": \"I\", \"escape\": 0.06589296274153902, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.0789, \"times_seen\": 56.0}, {\"site\": 1065, \"mutant\": \"K\", \"escape\": 0.23855832615829947, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.1811, \"times_seen\": 21.0}, {\"site\": 1065, \"mutant\": \"L\", \"escape\": -0.000362393463805953, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.6599, \"times_seen\": 122.0}, {\"site\": 1065, \"mutant\": \"M\", \"escape\": 0.0121222192857919, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.4082, \"times_seen\": 35.0}, {\"site\": 1065, \"mutant\": \"N\", \"escape\": 0.06600665689024773, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.7039, \"times_seen\": 10.0}, {\"site\": 1065, \"mutant\": \"P\", \"escape\": -0.008933891322603511, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.59, \"times_seen\": 11.0}, {\"site\": 1065, \"mutant\": \"Q\", \"escape\": 0.05883143695125572, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.6464, \"times_seen\": 33.0}, {\"site\": 1065, \"mutant\": \"R\", \"escape\": 0.08264425958984178, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -0.9362, \"times_seen\": 64.0}, {\"site\": 1065, \"mutant\": \"S\", \"escape\": 0.078606270950106, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.2309, \"times_seen\": 36.0}, {\"site\": 1065, \"mutant\": \"T\", \"escape\": 0.014267370987180596, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -1.7788, \"times_seen\": 29.0}, {\"site\": 1065, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1065, \"mutant\": \"W\", \"escape\": -0.033440954552405415, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.3901, \"times_seen\": 8.0}, {\"site\": 1065, \"mutant\": \"Y\", \"escape\": -0.004458328959690158, \"epitope\": \"epitope 1\", \"reference_site\": \"1068\", \"functional effect\": -2.8595, \"times_seen\": 2.0}, {\"site\": 1066, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"H\", \"escape\": -0.011967454686571958, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.8035, \"times_seen\": 6.0}, {\"site\": 1066, \"mutant\": \"L\", \"escape\": -0.0038661315191849343, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.9453, \"times_seen\": 2.0}, {\"site\": 1066, \"mutant\": \"M\", \"escape\": -0.0014587865218879642, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.8659, \"times_seen\": 1.0}, {\"site\": 1066, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.9985, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"S\", \"escape\": 0.03318312688458576, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -2.1741, \"times_seen\": 32.0}, {\"site\": 1066, \"mutant\": \"T\", \"escape\": 0.006887925889940956, \"epitope\": \"epitope 1\", \"reference_site\": \"1069\", \"functional effect\": -1.1377, \"times_seen\": 15.0}, {\"site\": 1067, \"mutant\": \"-\", \"escape\": 0.021212379759004807, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1067, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1067, \"mutant\": \"C\", \"escape\": 0.003845051284068492, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -0.5238, \"times_seen\": 12.0}, {\"site\": 1067, \"mutant\": \"D\", \"escape\": -0.0031572250922421215, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -2.3483, \"times_seen\": 2.0}, {\"site\": 1067, \"mutant\": \"E\", \"escape\": -0.03498990908936467, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.2697, \"times_seen\": 23.0}, {\"site\": 1067, \"mutant\": \"G\", \"escape\": -0.011205739349820555, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -0.4643, \"times_seen\": 34.0}, {\"site\": 1067, \"mutant\": \"M\", \"escape\": -0.01938607491428331, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.3362, \"times_seen\": 11.0}, {\"site\": 1067, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 1067, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -3.0417, \"times_seen\": null}, {\"site\": 1067, \"mutant\": \"S\", \"escape\": -0.031803213759267014, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": -0.3005, \"times_seen\": 52.0}, {\"site\": 1067, \"mutant\": \"T\", \"escape\": 0.029388113320885225, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.4444, \"times_seen\": 97.0}, {\"site\": 1067, \"mutant\": \"V\", \"escape\": 0.02702049447604956, \"epitope\": \"epitope 1\", \"reference_site\": \"1070\", \"functional effect\": 0.1886, \"times_seen\": 52.0}, {\"site\": 1068, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 1068, \"mutant\": \"-\", \"escape\": 0.022321558560846163, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1068, \"mutant\": \"E\", \"escape\": 0.014626433321038416, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.506, \"times_seen\": 24.0}, {\"site\": 1068, \"mutant\": \"H\", \"escape\": 0.0016877137232112014, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -1.27, \"times_seen\": 45.0}, {\"site\": 1068, \"mutant\": \"K\", \"escape\": -0.06764113015553544, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.0109, \"times_seen\": 25.0}, {\"site\": 1068, \"mutant\": \"L\", \"escape\": -0.27772068011126183, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.5261, \"times_seen\": 77.0}, {\"site\": 1068, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -2.9223, \"times_seen\": null}, {\"site\": 1068, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1068, \"mutant\": \"R\", \"escape\": 0.5017875787549374, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -0.2455, \"times_seen\": 77.0}, {\"site\": 1068, \"mutant\": \"T\", \"escape\": 0.09572043070910666, \"epitope\": \"epitope 1\", \"reference_site\": \"1071\", \"functional effect\": -1.2601, \"times_seen\": 9.0}, {\"site\": 1069, \"mutant\": \"*\", \"escape\": -0.02047489407753406, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.382, \"times_seen\": 3.0}, {\"site\": 1069, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1069, \"mutant\": \"A\", \"escape\": -0.03062880342207196, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": 0.4134, \"times_seen\": 9.0}, {\"site\": 1069, \"mutant\": \"D\", \"escape\": 0.027302102253739476, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.3371, \"times_seen\": 21.0}, {\"site\": 1069, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1069, \"mutant\": \"G\", \"escape\": -0.023056401819439902, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.4297, \"times_seen\": 3.0}, {\"site\": 1069, \"mutant\": \"H\", \"escape\": 0.0076579141105269245, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -0.3225, \"times_seen\": 1.0}, {\"site\": 1069, \"mutant\": \"K\", \"escape\": -0.09100799676053835, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.5922, \"times_seen\": 52.0}, {\"site\": 1069, \"mutant\": \"Q\", \"escape\": 0.2501682038614846, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": 0.1158, \"times_seen\": 50.0}, {\"site\": 1069, \"mutant\": \"R\", \"escape\": -1.3935568598843509, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -2.3716, \"times_seen\": 9.0}, {\"site\": 1069, \"mutant\": \"V\", \"escape\": -3.2392197701179275, \"epitope\": \"epitope 1\", \"reference_site\": \"1072\", \"functional effect\": -1.6824, \"times_seen\": 20.0}, {\"site\": 1070, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1070, \"mutant\": \"E\", \"escape\": 0.00910318073979351, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.3758, \"times_seen\": 54.0}, {\"site\": 1070, \"mutant\": \"H\", \"escape\": -0.004941239904327848, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.4496, \"times_seen\": 15.0}, {\"site\": 1070, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1070, \"mutant\": \"M\", \"escape\": -0.5721639467981531, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.0038, \"times_seen\": 87.0}, {\"site\": 1070, \"mutant\": \"N\", \"escape\": -0.05186944189350861, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.4858, \"times_seen\": 39.0}, {\"site\": 1070, \"mutant\": \"Q\", \"escape\": -0.012414194908671966, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.013, \"times_seen\": 25.0}, {\"site\": 1070, \"mutant\": \"R\", \"escape\": 0.16631455111681753, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": 0.0736, \"times_seen\": 112.0}, {\"site\": 1070, \"mutant\": \"T\", \"escape\": -0.04816991571807541, \"epitope\": \"epitope 1\", \"reference_site\": \"1073\", \"functional effect\": -0.6264, \"times_seen\": 50.0}, {\"site\": 1071, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1071, \"mutant\": \"D\", \"escape\": 0.03982932423008362, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.441, \"times_seen\": 70.0}, {\"site\": 1071, \"mutant\": \"E\", \"escape\": -0.007497898692838725, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.3182, \"times_seen\": 11.0}, {\"site\": 1071, \"mutant\": \"H\", \"escape\": 0.03003413529297524, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.6686, \"times_seen\": 22.0}, {\"site\": 1071, \"mutant\": \"I\", \"escape\": 0.015125712533792987, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.3058, \"times_seen\": 42.0}, {\"site\": 1071, \"mutant\": \"K\", \"escape\": -0.013968810899160472, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -0.648, \"times_seen\": 52.0}, {\"site\": 1071, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1071, \"mutant\": \"S\", \"escape\": 0.0010102326821009354, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.4069, \"times_seen\": 65.0}, {\"site\": 1071, \"mutant\": \"T\", \"escape\": -0.030871278540611384, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": 0.3442, \"times_seen\": 23.0}, {\"site\": 1071, \"mutant\": \"Y\", \"escape\": 0.0029359098643006974, \"epitope\": \"epitope 1\", \"reference_site\": \"1074\", \"functional effect\": -1.2563, \"times_seen\": 20.0}, {\"site\": 1072, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1072, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1072, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -2.793, \"times_seen\": null}, {\"site\": 1072, \"mutant\": \"L\", \"escape\": -0.05182557562700798, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": 0.1042, \"times_seen\": 27.0}, {\"site\": 1072, \"mutant\": \"S\", \"escape\": -0.005682496715103542, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -2.9691, \"times_seen\": 1.0}, {\"site\": 1072, \"mutant\": \"V\", \"escape\": -0.04906786674268647, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -1.3245, \"times_seen\": 29.0}, {\"site\": 1072, \"mutant\": \"Y\", \"escape\": -0.039578461122078655, \"epitope\": \"epitope 1\", \"reference_site\": \"1075\", \"functional effect\": -0.1886, \"times_seen\": 34.0}, {\"site\": 1073, \"mutant\": \"A\", \"escape\": 0.01957678541672895, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -1.4501, \"times_seen\": 19.0}, {\"site\": 1073, \"mutant\": \"H\", \"escape\": -0.044951918244023004, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -1.2811, \"times_seen\": 10.0}, {\"site\": 1073, \"mutant\": \"I\", \"escape\": -0.09594904998429751, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": 0.0389, \"times_seen\": 76.0}, {\"site\": 1073, \"mutant\": \"L\", \"escape\": -0.004258701983807403, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -0.1396, \"times_seen\": 2.0}, {\"site\": 1073, \"mutant\": \"N\", \"escape\": -0.007715439492415179, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -1.4546, \"times_seen\": 2.0}, {\"site\": 1073, \"mutant\": \"S\", \"escape\": -0.007904163569339102, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": -0.921, \"times_seen\": 66.0}, {\"site\": 1073, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1076\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"A\", \"escape\": -0.05873554680278308, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": 0.1939, \"times_seen\": 53.0}, {\"site\": 1074, \"mutant\": \"I\", \"escape\": 0.0157206791379624, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.176, \"times_seen\": 3.0}, {\"site\": 1074, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.5151, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.8967, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"N\", \"escape\": -0.005520426589154765, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -1.5999, \"times_seen\": 8.0}, {\"site\": 1074, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -0.9705, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"S\", \"escape\": -0.013723194673697273, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -0.8197, \"times_seen\": 14.0}, {\"site\": 1074, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"V\", \"escape\": -0.10770723138448131, \"epitope\": \"epitope 1\", \"reference_site\": \"1077\", \"functional effect\": -2.5227, \"times_seen\": 7.0}, {\"site\": 1075, \"mutant\": \"*\", \"escape\": -0.0038939878958494725, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 1075, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1075, \"mutant\": \"C\", \"escape\": 0.011981233801497609, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.7531, \"times_seen\": 20.0}, {\"site\": 1075, \"mutant\": \"D\", \"escape\": -0.01092481145148298, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.0754, \"times_seen\": 3.0}, {\"site\": 1075, \"mutant\": \"E\", \"escape\": -0.007357621856865722, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.0433, \"times_seen\": 2.0}, {\"site\": 1075, \"mutant\": \"F\", \"escape\": -0.006555365286678197, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.4729, \"times_seen\": 8.0}, {\"site\": 1075, \"mutant\": \"G\", \"escape\": -0.031228885333691354, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.6183, \"times_seen\": 53.0}, {\"site\": 1075, \"mutant\": \"H\", \"escape\": -0.014570535828438733, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.7754, \"times_seen\": 6.0}, {\"site\": 1075, \"mutant\": \"I\", \"escape\": -0.007078219032328421, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -1.9792, \"times_seen\": 3.0}, {\"site\": 1075, \"mutant\": \"K\", \"escape\": -0.009665820735663307, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.0339, \"times_seen\": 2.0}, {\"site\": 1075, \"mutant\": \"L\", \"escape\": -0.012537609553196263, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.9199, \"times_seen\": 5.0}, {\"site\": 1075, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.8288, \"times_seen\": null}, {\"site\": 1075, \"mutant\": \"N\", \"escape\": -0.010200924933194178, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.7906, \"times_seen\": 3.0}, {\"site\": 1075, \"mutant\": \"P\", \"escape\": 0.006639298505942733, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.6398, \"times_seen\": 1.0}, {\"site\": 1075, \"mutant\": \"Q\", \"escape\": 0.038129735113240006, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.6828, \"times_seen\": 2.0}, {\"site\": 1075, \"mutant\": \"R\", \"escape\": -0.04983224792993492, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.0061, \"times_seen\": 8.0}, {\"site\": 1075, \"mutant\": \"S\", \"escape\": -1.4052888725669994, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.437, \"times_seen\": 72.0}, {\"site\": 1075, \"mutant\": \"T\", \"escape\": 0.8355122848781992, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -0.7051, \"times_seen\": 96.0}, {\"site\": 1075, \"mutant\": \"V\", \"escape\": -0.01231980190316231, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.1939, \"times_seen\": 28.0}, {\"site\": 1075, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -3.1007, \"times_seen\": null}, {\"site\": 1075, \"mutant\": \"Y\", \"escape\": -0.010131617770573165, \"epitope\": \"epitope 1\", \"reference_site\": \"1078\", \"functional effect\": -2.8147, \"times_seen\": 3.0}, {\"site\": 1076, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -0.3029, \"times_seen\": null}, {\"site\": 1076, \"mutant\": \"H\", \"escape\": -0.010249381891916425, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -1.5482, \"times_seen\": 3.0}, {\"site\": 1076, \"mutant\": \"L\", \"escape\": -0.0034870296918911377, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1076, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1076, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -3.2643, \"times_seen\": null}, {\"site\": 1076, \"mutant\": \"S\", \"escape\": -0.020056414784112887, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -0.5505, \"times_seen\": 19.0}, {\"site\": 1076, \"mutant\": \"T\", \"escape\": 0.005387468090740798, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": 0.2181, \"times_seen\": 44.0}, {\"site\": 1076, \"mutant\": \"V\", \"escape\": 0.039835682833575116, \"epitope\": \"epitope 1\", \"reference_site\": \"1079\", \"functional effect\": -2.3128, \"times_seen\": 1.0}, {\"site\": 1077, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1077, \"mutant\": \"C\", \"escape\": 0.0012366610558008253, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -1.1145, \"times_seen\": 5.0}, {\"site\": 1077, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -0.3397, \"times_seen\": null}, {\"site\": 1077, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1077, \"mutant\": \"S\", \"escape\": -0.012484677670543044, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -0.4165, \"times_seen\": 27.0}, {\"site\": 1077, \"mutant\": \"T\", \"escape\": -0.007857861120665173, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -2.092, \"times_seen\": 11.0}, {\"site\": 1077, \"mutant\": \"V\", \"escape\": 0.0026846387599278186, \"epitope\": \"epitope 1\", \"reference_site\": \"1080\", \"functional effect\": -2.1791, \"times_seen\": 5.0}, {\"site\": 1078, \"mutant\": \"F\", \"escape\": 0.17619876005731652, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.4039, \"times_seen\": 57.0}, {\"site\": 1078, \"mutant\": \"H\", \"escape\": 0.028842878537477773, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -2.9388, \"times_seen\": 5.0}, {\"site\": 1078, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1078, \"mutant\": \"L\", \"escape\": -0.024056215742936687, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.7406, \"times_seen\": 7.0}, {\"site\": 1078, \"mutant\": \"M\", \"escape\": 0.01994068713074359, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.0659, \"times_seen\": 23.0}, {\"site\": 1078, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -3.0036, \"times_seen\": null}, {\"site\": 1078, \"mutant\": \"T\", \"escape\": -0.019401962048271746, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -1.4291, \"times_seen\": 10.0}, {\"site\": 1078, \"mutant\": \"V\", \"escape\": 0.002889894953441131, \"epitope\": \"epitope 1\", \"reference_site\": \"1081\", \"functional effect\": -0.3121, \"times_seen\": 30.0}, {\"site\": 1079, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -3.0716, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -3.0067, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.2886, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"R\", \"escape\": 0.01604491837556078, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.469, \"times_seen\": 3.0}, {\"site\": 1079, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"Y\", \"escape\": -0.007600090640585969, \"epitope\": \"epitope 1\", \"reference_site\": \"1082\", \"functional effect\": -2.5589, \"times_seen\": 2.0}, {\"site\": 1080, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1080, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1080, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1080, \"mutant\": \"N\", \"escape\": 0.010976749880072953, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.003, \"times_seen\": 6.0}, {\"site\": 1080, \"mutant\": \"Q\", \"escape\": 0.0017196275911778875, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.7085, \"times_seen\": 4.0}, {\"site\": 1080, \"mutant\": \"R\", \"escape\": -0.0001473677902737294, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.1981, \"times_seen\": 2.0}, {\"site\": 1080, \"mutant\": \"Y\", \"escape\": 0.048326199188693304, \"epitope\": \"epitope 1\", \"reference_site\": \"1083\", \"functional effect\": -0.163, \"times_seen\": 9.0}, {\"site\": 1081, \"mutant\": \"A\", \"escape\": 0.0021933302372299356, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.2165, \"times_seen\": 5.0}, {\"site\": 1081, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1081, \"mutant\": \"E\", \"escape\": -0.03928355300735921, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.1137, \"times_seen\": 25.0}, {\"site\": 1081, \"mutant\": \"G\", \"escape\": -0.019047018569003052, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.0057, \"times_seen\": 18.0}, {\"site\": 1081, \"mutant\": \"H\", \"escape\": -1.3245904725500075, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": 0.2472, \"times_seen\": 6.0}, {\"site\": 1081, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.189, \"times_seen\": null}, {\"site\": 1081, \"mutant\": \"N\", \"escape\": 0.06488041098490689, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": 0.2612, \"times_seen\": 17.0}, {\"site\": 1081, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.0339, \"times_seen\": null}, {\"site\": 1081, \"mutant\": \"V\", \"escape\": -0.010907813347477048, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.2983, \"times_seen\": 8.0}, {\"site\": 1081, \"mutant\": \"Y\", \"escape\": 0.002013989800384045, \"epitope\": \"epitope 1\", \"reference_site\": \"1084\", \"functional effect\": -0.239, \"times_seen\": 3.0}, {\"site\": 1082, \"mutant\": \"A\", \"escape\": 0.017772456376914842, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.0323, \"times_seen\": 25.0}, {\"site\": 1082, \"mutant\": \"C\", \"escape\": -0.0035115615497940287, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -1.0749, \"times_seen\": 1.0}, {\"site\": 1082, \"mutant\": \"D\", \"escape\": -0.04356203807291201, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.1623, \"times_seen\": 48.0}, {\"site\": 1082, \"mutant\": \"E\", \"escape\": -0.056384903064689955, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -0.0241, \"times_seen\": 28.0}, {\"site\": 1082, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1082, \"mutant\": \"L\", \"escape\": 0.007933458743128981, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -0.1119, \"times_seen\": 5.0}, {\"site\": 1082, \"mutant\": \"R\", \"escape\": -0.0014245227667337272, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": 0.1736, \"times_seen\": 15.0}, {\"site\": 1082, \"mutant\": \"S\", \"escape\": 0.009412861676159323, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -0.1385, \"times_seen\": 21.0}, {\"site\": 1082, \"mutant\": \"V\", \"escape\": 0.014244083460632755, \"epitope\": \"epitope 1\", \"reference_site\": \"1085\", \"functional effect\": -2.2934, \"times_seen\": 4.0}, {\"site\": 1083, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -3.0347, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"E\", \"escape\": -0.026793168136070356, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.3973, \"times_seen\": 24.0}, {\"site\": 1083, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"I\", \"escape\": -0.008432807149191682, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.2824, \"times_seen\": 6.0}, {\"site\": 1083, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"L\", \"escape\": -0.01858322666899225, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.5523, \"times_seen\": 8.0}, {\"site\": 1083, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.4516, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"N\", \"escape\": 0.03564115963028174, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.7429, \"times_seen\": 15.0}, {\"site\": 1083, \"mutant\": \"Q\", \"escape\": 0.0065645023799940005, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.4261, \"times_seen\": 13.0}, {\"site\": 1083, \"mutant\": \"R\", \"escape\": 0.010657410567341222, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": 0.1127, \"times_seen\": 52.0}, {\"site\": 1083, \"mutant\": \"T\", \"escape\": -0.003363733918758842, \"epitope\": \"epitope 1\", \"reference_site\": \"1086\", \"functional effect\": -0.0806, \"times_seen\": 2.0}, {\"site\": 1084, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -2.078, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.4293, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.5309, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"S\", \"escape\": 0.019102582378197456, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": 0.0105, \"times_seen\": 13.0}, {\"site\": 1084, \"mutant\": \"T\", \"escape\": -0.11988646049254895, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.0232, \"times_seen\": 20.0}, {\"site\": 1084, \"mutant\": \"V\", \"escape\": -0.0006488100316329203, \"epitope\": \"epitope 1\", \"reference_site\": \"1087\", \"functional effect\": -1.8206, \"times_seen\": 15.0}, {\"site\": 1085, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1085, \"mutant\": \"L\", \"escape\": 0.002834221355685988, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -1.4304, \"times_seen\": 1.0}, {\"site\": 1085, \"mutant\": \"N\", \"escape\": 0.00502185864963116, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -0.7507, \"times_seen\": 7.0}, {\"site\": 1085, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -1.2344, \"times_seen\": null}, {\"site\": 1085, \"mutant\": \"R\", \"escape\": 0.20320716059263785, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -0.1165, \"times_seen\": 7.0}, {\"site\": 1085, \"mutant\": \"T\", \"escape\": -0.021253093434927574, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": -0.3033, \"times_seen\": 8.0}, {\"site\": 1085, \"mutant\": \"Y\", \"escape\": 0.01624368885770648, \"epitope\": \"epitope 1\", \"reference_site\": \"1088\", \"functional effect\": 0.2076, \"times_seen\": 64.0}, {\"site\": 1086, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1086, \"mutant\": \"I\", \"escape\": -0.004770979577218116, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -1.8346, \"times_seen\": 2.0}, {\"site\": 1086, \"mutant\": \"L\", \"escape\": -0.00796164965218748, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -1.3854, \"times_seen\": 3.0}, {\"site\": 1086, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -3.1209, \"times_seen\": null}, {\"site\": 1086, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": -0.1576, \"times_seen\": null}, {\"site\": 1086, \"mutant\": \"Y\", \"escape\": -0.029772642932305138, \"epitope\": \"epitope 1\", \"reference_site\": \"1089\", \"functional effect\": 0.394, \"times_seen\": 21.0}, {\"site\": 1087, \"mutant\": \"A\", \"escape\": -0.010001637924919177, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -0.1195, \"times_seen\": 2.0}, {\"site\": 1087, \"mutant\": \"L\", \"escape\": -0.025141756081634607, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -1.4863, \"times_seen\": 9.0}, {\"site\": 1087, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1087, \"mutant\": \"Q\", \"escape\": 0.017783926086259595, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -2.0288, \"times_seen\": 1.0}, {\"site\": 1087, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -1.166, \"times_seen\": null}, {\"site\": 1087, \"mutant\": \"S\", \"escape\": -0.13104923072498623, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -0.3631, \"times_seen\": 33.0}, {\"site\": 1087, \"mutant\": \"T\", \"escape\": 0.017106041057576633, \"epitope\": \"epitope 1\", \"reference_site\": \"1090\", \"functional effect\": -0.4244, \"times_seen\": 1.0}, {\"site\": 1088, \"mutant\": \"C\", \"escape\": -0.01317017602547873, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -1.6448, \"times_seen\": 7.0}, {\"site\": 1088, \"mutant\": \"G\", \"escape\": -0.0003693320342781336, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -0.0665, \"times_seen\": 38.0}, {\"site\": 1088, \"mutant\": \"H\", \"escape\": -0.008073431804962634, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -0.3618, \"times_seen\": 5.0}, {\"site\": 1088, \"mutant\": \"K\", \"escape\": -0.8715816704221256, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.3108, \"times_seen\": 21.0}, {\"site\": 1088, \"mutant\": \"L\", \"escape\": 0.014783669978340734, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -1.0451, \"times_seen\": 5.0}, {\"site\": 1088, \"mutant\": \"M\", \"escape\": -0.005571150455337044, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -1.0036, \"times_seen\": 4.0}, {\"site\": 1088, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1088, \"mutant\": \"S\", \"escape\": 0.025677735213581035, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.2589, \"times_seen\": 12.0}, {\"site\": 1088, \"mutant\": \"T\", \"escape\": -0.010765765979233632, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 1088, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1091\", \"functional effect\": -3.1836, \"times_seen\": null}, {\"site\": 1089, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -2.1064, \"times_seen\": null}, {\"site\": 1089, \"mutant\": \"A\", \"escape\": -0.00988726125144701, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -0.5347, \"times_seen\": 8.0}, {\"site\": 1089, \"mutant\": \"D\", \"escape\": -0.05099013944019633, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": 0.2621, \"times_seen\": 25.0}, {\"site\": 1089, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1089, \"mutant\": \"G\", \"escape\": 0.001170534069255478, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -1.3051, \"times_seen\": 24.0}, {\"site\": 1089, \"mutant\": \"K\", \"escape\": 0.004325910496918605, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -1.5301, \"times_seen\": 32.0}, {\"site\": 1089, \"mutant\": \"Q\", \"escape\": -0.019595026839769304, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -0.7884, \"times_seen\": 17.0}, {\"site\": 1089, \"mutant\": \"V\", \"escape\": -0.020222103329083137, \"epitope\": \"epitope 1\", \"reference_site\": \"1092\", \"functional effect\": -0.9278, \"times_seen\": 13.0}, {\"site\": 1090, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -0.8553, \"times_seen\": null}, {\"site\": 1090, \"mutant\": \"E\", \"escape\": -0.02501612852630406, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -2.5162, \"times_seen\": 2.0}, {\"site\": 1090, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1090, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -0.3222, \"times_seen\": null}, {\"site\": 1090, \"mutant\": \"R\", \"escape\": -0.8753480058729608, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -0.8766, \"times_seen\": 26.0}, {\"site\": 1090, \"mutant\": \"S\", \"escape\": -0.014965989668682261, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -1.0177, \"times_seen\": 5.0}, {\"site\": 1090, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1093\", \"functional effect\": -2.3225, \"times_seen\": null}, {\"site\": 1091, \"mutant\": \"A\", \"escape\": -0.024863903211404012, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -1.5209, \"times_seen\": 12.0}, {\"site\": 1091, \"mutant\": \"F\", \"escape\": 0.010589112688796618, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": 0.223, \"times_seen\": 24.0}, {\"site\": 1091, \"mutant\": \"I\", \"escape\": -0.025347302071468934, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -1.4895, \"times_seen\": 9.0}, {\"site\": 1091, \"mutant\": \"L\", \"escape\": -0.00917882688330617, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -2.3822, \"times_seen\": 5.0}, {\"site\": 1091, \"mutant\": \"M\", \"escape\": 0.022716428028701323, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -1.3913, \"times_seen\": 6.0}, {\"site\": 1091, \"mutant\": \"T\", \"escape\": -0.0112040791113328, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": -0.105, \"times_seen\": 6.0}, {\"site\": 1091, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1094\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"L\", \"escape\": -0.030668283109166312, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -0.5826, \"times_seen\": 35.0}, {\"site\": 1092, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -2.9443, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -1.1874, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"Y\", \"escape\": 0.6954818385326714, \"epitope\": \"epitope 1\", \"reference_site\": \"1095\", \"functional effect\": -0.2225, \"times_seen\": 25.0}, {\"site\": 1093, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1093, \"mutant\": \"A\", \"escape\": -0.04285507086051992, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": 0.3309, \"times_seen\": 13.0}, {\"site\": 1093, \"mutant\": \"E\", \"escape\": 0.015976920973193566, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -2.2618, \"times_seen\": 1.0}, {\"site\": 1093, \"mutant\": \"F\", \"escape\": -0.017817295178489404, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -2.2925, \"times_seen\": 2.0}, {\"site\": 1093, \"mutant\": \"I\", \"escape\": -0.017611813535369725, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": 0.3568, \"times_seen\": 79.0}, {\"site\": 1093, \"mutant\": \"L\", \"escape\": -0.08653446949410248, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -0.4912, \"times_seen\": 22.0}, {\"site\": 1093, \"mutant\": \"M\", \"escape\": -0.02325370209849643, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": -0.7564, \"times_seen\": 35.0}, {\"site\": 1093, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1096\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1094, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1094, \"mutant\": \"A\", \"escape\": 0.01766225705856175, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -0.3257, \"times_seen\": 15.0}, {\"site\": 1094, \"mutant\": \"C\", \"escape\": -0.05351448889465292, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 1094, \"mutant\": \"G\", \"escape\": -0.020560017757923463, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.0757, \"times_seen\": 17.0}, {\"site\": 1094, \"mutant\": \"I\", \"escape\": -0.002768006928391614, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -1.405, \"times_seen\": 1.0}, {\"site\": 1094, \"mutant\": \"L\", \"escape\": 0.006711694467600678, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -0.6398, \"times_seen\": 5.0}, {\"site\": 1094, \"mutant\": \"N\", \"escape\": 0.1952998934626723, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.4231, \"times_seen\": 71.0}, {\"site\": 1094, \"mutant\": \"R\", \"escape\": -0.009362044328835254, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.158, \"times_seen\": 2.0}, {\"site\": 1094, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1094, \"mutant\": \"T\", \"escape\": -0.016519118101699586, \"epitope\": \"epitope 1\", \"reference_site\": \"1097\", \"functional effect\": -2.1066, \"times_seen\": 8.0}, {\"site\": 1095, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1095, \"mutant\": \"D\", \"escape\": -0.0038236714948842827, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 1095, \"mutant\": \"H\", \"escape\": 0.005334456125199884, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.5034, \"times_seen\": 14.0}, {\"site\": 1095, \"mutant\": \"I\", \"escape\": -0.0038107625569871358, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.5287, \"times_seen\": 1.0}, {\"site\": 1095, \"mutant\": \"K\", \"escape\": -0.009108607207996711, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -1.0252, \"times_seen\": 3.0}, {\"site\": 1095, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1095, \"mutant\": \"Q\", \"escape\": -0.05827673898150447, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.536, \"times_seen\": 24.0}, {\"site\": 1095, \"mutant\": \"S\", \"escape\": -0.006155015637838768, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": -0.0463, \"times_seen\": 12.0}, {\"site\": 1095, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1098\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1096, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -1.4413, \"times_seen\": null}, {\"site\": 1096, \"mutant\": \"A\", \"escape\": -0.0002969456350281525, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": 0.2974, \"times_seen\": 1.0}, {\"site\": 1096, \"mutant\": \"C\", \"escape\": 0.001147217380796667, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.8839, \"times_seen\": 27.0}, {\"site\": 1096, \"mutant\": \"D\", \"escape\": -0.03508089946840558, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.263, \"times_seen\": 140.0}, {\"site\": 1096, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1096, \"mutant\": \"K\", \"escape\": -0.018338992951931223, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.1589, \"times_seen\": 6.0}, {\"site\": 1096, \"mutant\": \"S\", \"escape\": -0.016048992933432128, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.217, \"times_seen\": 72.0}, {\"site\": 1096, \"mutant\": \"T\", \"escape\": -0.0004497510331728665, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.2863, \"times_seen\": 13.0}, {\"site\": 1096, \"mutant\": \"V\", \"escape\": 0.009896679503048848, \"epitope\": \"epitope 1\", \"reference_site\": \"1099\", \"functional effect\": -0.5929, \"times_seen\": 28.0}, {\"site\": 1097, \"mutant\": \"A\", \"escape\": -0.3074494462016307, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": -0.0827, \"times_seen\": 32.0}, {\"site\": 1097, \"mutant\": \"I\", \"escape\": 0.05610260553676893, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": -0.0143, \"times_seen\": 71.0}, {\"site\": 1097, \"mutant\": \"K\", \"escape\": -0.01377558325837623, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": 0.0987, \"times_seen\": 12.0}, {\"site\": 1097, \"mutant\": \"N\", \"escape\": -0.04370537530857974, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": 0.1204, \"times_seen\": 4.0}, {\"site\": 1097, \"mutant\": \"S\", \"escape\": -0.04376378733338728, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": -0.0231, \"times_seen\": 39.0}, {\"site\": 1097, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1100\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"D\", \"escape\": 0.17700592727105252, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.0306, \"times_seen\": 83.0}, {\"site\": 1098, \"mutant\": \"E\", \"escape\": -0.01268255684358211, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1584, \"times_seen\": 19.0}, {\"site\": 1098, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"L\", \"escape\": -0.01104030134484034, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1489, \"times_seen\": 17.0}, {\"site\": 1098, \"mutant\": \"N\", \"escape\": 0.004363479125058994, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.0334, \"times_seen\": 44.0}, {\"site\": 1098, \"mutant\": \"Q\", \"escape\": 0.3745302111050302, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1925, \"times_seen\": 83.0}, {\"site\": 1098, \"mutant\": \"R\", \"escape\": 0.009980919473490996, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.0986, \"times_seen\": 24.0}, {\"site\": 1098, \"mutant\": \"T\", \"escape\": 0.006030497111168244, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": -0.1924, \"times_seen\": 1.0}, {\"site\": 1098, \"mutant\": \"Y\", \"escape\": -0.0449544896358959, \"epitope\": \"epitope 1\", \"reference_site\": \"1101\", \"functional effect\": 0.0633, \"times_seen\": 127.0}, {\"site\": 1099, \"mutant\": \"*\", \"escape\": -0.009339403265485963, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -1.9349, \"times_seen\": 3.0}, {\"site\": 1099, \"mutant\": \"C\", \"escape\": -0.003275341827343458, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.729, \"times_seen\": 6.0}, {\"site\": 1099, \"mutant\": \"F\", \"escape\": -0.006264395547647123, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": 0.0646, \"times_seen\": 16.0}, {\"site\": 1099, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 1099, \"mutant\": \"L\", \"escape\": 0.04796027949845715, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -1.6568, \"times_seen\": 28.0}, {\"site\": 1099, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1099, \"mutant\": \"S\", \"escape\": 0.01788257769770977, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.9385, \"times_seen\": 2.0}, {\"site\": 1099, \"mutant\": \"T\", \"escape\": -0.012030211230227517, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": -2.2473, \"times_seen\": 6.0}, {\"site\": 1099, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1102\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"C\", \"escape\": -0.037577246799263685, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": -0.6281, \"times_seen\": 12.0}, {\"site\": 1100, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"I\", \"escape\": 0.0016008745530428766, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.0246, \"times_seen\": 1.0}, {\"site\": 1100, \"mutant\": \"L\", \"escape\": 0.0158661991706964, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": -0.1738, \"times_seen\": 52.0}, {\"site\": 1100, \"mutant\": \"S\", \"escape\": -0.022543344562741117, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.2814, \"times_seen\": 49.0}, {\"site\": 1100, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.0507, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"Y\", \"escape\": -0.009058172342303106, \"epitope\": \"epitope 1\", \"reference_site\": \"1103\", \"functional effect\": 0.4077, \"times_seen\": 5.0}, {\"site\": 1101, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1101, \"mutant\": \"A\", \"escape\": -1.0611757845198555, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -1.4398, \"times_seen\": 3.0}, {\"site\": 1101, \"mutant\": \"E\", \"escape\": 0.007723918188707503, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.0063, \"times_seen\": 5.0}, {\"site\": 1101, \"mutant\": \"I\", \"escape\": -0.25051657992240406, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.1818, \"times_seen\": 19.0}, {\"site\": 1101, \"mutant\": \"L\", \"escape\": -0.08070650864596547, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.4747, \"times_seen\": 29.0}, {\"site\": 1101, \"mutant\": \"M\", \"escape\": 0.03771480359665781, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -0.0126, \"times_seen\": 8.0}, {\"site\": 1101, \"mutant\": \"T\", \"escape\": 0.0001410817203123676, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": -1.5585, \"times_seen\": 3.0}, {\"site\": 1101, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1104\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"A\", \"escape\": -0.002310375161650929, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 1102, \"mutant\": \"I\", \"escape\": 0.00013451604279729576, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -3.1318, \"times_seen\": 1.0}, {\"site\": 1102, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -2.867, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": -2.6567, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1105\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"*\", \"escape\": -0.005406919623546388, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.9491, \"times_seen\": 1.0}, {\"site\": 1103, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.0867, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"H\", \"escape\": -0.2635806342332563, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.739, \"times_seen\": 4.0}, {\"site\": 1103, \"mutant\": \"K\", \"escape\": -0.01687713458155119, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.4537, \"times_seen\": 8.0}, {\"site\": 1103, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.7148, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"R\", \"escape\": -0.008049876416212626, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.9677, \"times_seen\": 2.0}, {\"site\": 1103, \"mutant\": \"T\", \"escape\": -0.0038700784785726, \"epitope\": \"epitope 1\", \"reference_site\": \"1106\", \"functional effect\": -2.1603, \"times_seen\": 1.0}, {\"site\": 1104, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1104, \"mutant\": \"G\", \"escape\": -0.03618682260811417, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.9585, \"times_seen\": 13.0}, {\"site\": 1104, \"mutant\": \"K\", \"escape\": -0.042111169671569616, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0633, \"times_seen\": 59.0}, {\"site\": 1104, \"mutant\": \"L\", \"escape\": -0.02427426286876924, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0679, \"times_seen\": 15.0}, {\"site\": 1104, \"mutant\": \"M\", \"escape\": 0.829681659999881, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0667, \"times_seen\": 68.0}, {\"site\": 1104, \"mutant\": \"N\", \"escape\": 0.05451975712398635, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.0549, \"times_seen\": 8.0}, {\"site\": 1104, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1104, \"mutant\": \"S\", \"escape\": -0.31870572992594437, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.0861, \"times_seen\": 35.0}, {\"site\": 1104, \"mutant\": \"T\", \"escape\": -0.012535840707515981, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.7845, \"times_seen\": 5.0}, {\"site\": 1104, \"mutant\": \"W\", \"escape\": -0.001953611718704283, \"epitope\": \"epitope 1\", \"reference_site\": \"1107\", \"functional effect\": -1.3463, \"times_seen\": 1.0}, {\"site\": 1105, \"mutant\": \"H\", \"escape\": 0.0002339726227576926, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -0.8893, \"times_seen\": 8.0}, {\"site\": 1105, \"mutant\": \"I\", \"escape\": 1.2095919316023587, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": 0.0578, \"times_seen\": 22.0}, {\"site\": 1105, \"mutant\": \"K\", \"escape\": 0.006257401795229485, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": 0.1833, \"times_seen\": 2.0}, {\"site\": 1105, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1105, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -1.8012, \"times_seen\": null}, {\"site\": 1105, \"mutant\": \"S\", \"escape\": -0.004060450530702814, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -2.3399, \"times_seen\": 20.0}, {\"site\": 1105, \"mutant\": \"T\", \"escape\": 0.08149860342303032, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -2.3165, \"times_seen\": 10.0}, {\"site\": 1105, \"mutant\": \"Y\", \"escape\": -0.008478458185683541, \"epitope\": \"epitope 1\", \"reference_site\": \"1108\", \"functional effect\": -1.0527, \"times_seen\": 15.0}, {\"site\": 1106, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1106, \"mutant\": \"I\", \"escape\": -0.045212460777544095, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": -1.3553, \"times_seen\": 10.0}, {\"site\": 1106, \"mutant\": \"L\", \"escape\": -0.36776537583908014, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": -0.8859, \"times_seen\": 26.0}, {\"site\": 1106, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": -2.9219, \"times_seen\": null}, {\"site\": 1106, \"mutant\": \"Y\", \"escape\": -0.005030331698727652, \"epitope\": \"epitope 1\", \"reference_site\": \"1109\", \"functional effect\": 0.2652, \"times_seen\": 18.0}, {\"site\": 1107, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -1.6801, \"times_seen\": null}, {\"site\": 1107, \"mutant\": \"C\", \"escape\": -0.012477952493321315, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -2.561, \"times_seen\": 2.0}, {\"site\": 1107, \"mutant\": \"F\", \"escape\": 0.009468825308158988, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": 0.066, \"times_seen\": 30.0}, {\"site\": 1107, \"mutant\": \"H\", \"escape\": -0.076377848573229, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -1.6806, \"times_seen\": 9.0}, {\"site\": 1107, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": -3.1111, \"times_seen\": null}, {\"site\": 1107, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1110\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1108, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.946, \"times_seen\": null}, {\"site\": 1108, \"mutant\": \"A\", \"escape\": 0.001537775834749095, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.2492, \"times_seen\": 11.0}, {\"site\": 1108, \"mutant\": \"D\", \"escape\": 0.0020742447952745977, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.7751, \"times_seen\": 12.0}, {\"site\": 1108, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1108, \"mutant\": \"G\", \"escape\": 0.008054676026137953, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.3871, \"times_seen\": 9.0}, {\"site\": 1108, \"mutant\": \"K\", \"escape\": 0.14818266818337408, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.8824, \"times_seen\": 41.0}, {\"site\": 1108, \"mutant\": \"Q\", \"escape\": -0.011358592890980547, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -0.0614, \"times_seen\": 12.0}, {\"site\": 1108, \"mutant\": \"R\", \"escape\": 0.02240558891013821, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -1.9665, \"times_seen\": 4.0}, {\"site\": 1108, \"mutant\": \"T\", \"escape\": -0.00018811234275725364, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.4665, \"times_seen\": 2.0}, {\"site\": 1108, \"mutant\": \"V\", \"escape\": 0.00026738662008625, \"epitope\": \"epitope 1\", \"reference_site\": \"1111\", \"functional effect\": -2.7096, \"times_seen\": 1.0}, {\"site\": 1109, \"mutant\": \"L\", \"escape\": -0.018572788529514484, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -2.4076, \"times_seen\": 11.0}, {\"site\": 1109, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1109, \"mutant\": \"Q\", \"escape\": 0.009384422355866584, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -0.7292, \"times_seen\": 43.0}, {\"site\": 1109, \"mutant\": \"S\", \"escape\": 0.11980159684091937, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -0.9911, \"times_seen\": 22.0}, {\"site\": 1109, \"mutant\": \"T\", \"escape\": -0.01435897771856914, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -1.7155, \"times_seen\": 10.0}, {\"site\": 1109, \"mutant\": \"V\", \"escape\": 0.02777703514227496, \"epitope\": \"epitope 1\", \"reference_site\": \"1112\", \"functional effect\": -1.9212, \"times_seen\": 7.0}, {\"site\": 1110, \"mutant\": \"*\", \"escape\": 0.005721165240839849, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -1.6966, \"times_seen\": 2.0}, {\"site\": 1110, \"mutant\": \"E\", \"escape\": 0.028395525171141165, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -0.8441, \"times_seen\": 15.0}, {\"site\": 1110, \"mutant\": \"H\", \"escape\": -0.013978738799565432, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 1110, \"mutant\": \"K\", \"escape\": -0.4448722282797866, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.3841, \"times_seen\": 26.0}, {\"site\": 1110, \"mutant\": \"L\", \"escape\": -0.4855822227484938, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.4138, \"times_seen\": 48.0}, {\"site\": 1110, \"mutant\": \"M\", \"escape\": 0.46343797924191077, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -0.2198, \"times_seen\": 13.0}, {\"site\": 1110, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": -2.7803, \"times_seen\": null}, {\"site\": 1110, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1110, \"mutant\": \"R\", \"escape\": -0.059669806167669086, \"epitope\": \"epitope 1\", \"reference_site\": \"1113\", \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1111, \"mutant\": \"F\", \"escape\": -0.009502096891944464, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": -0.0523, \"times_seen\": 13.0}, {\"site\": 1111, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1111, \"mutant\": \"L\", \"escape\": 0.025504630557040036, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": -0.1349, \"times_seen\": 25.0}, {\"site\": 1111, \"mutant\": \"M\", \"escape\": -0.019965127358254484, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 1111, \"mutant\": \"N\", \"escape\": 0.004295544640750694, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.2317, \"times_seen\": 9.0}, {\"site\": 1111, \"mutant\": \"S\", \"escape\": -0.01403438367904927, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.059, \"times_seen\": 7.0}, {\"site\": 1111, \"mutant\": \"T\", \"escape\": 0.0022221336969571828, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.1919, \"times_seen\": 16.0}, {\"site\": 1111, \"mutant\": \"V\", \"escape\": -1.9269884574036367, \"epitope\": \"epitope 1\", \"reference_site\": \"1114\", \"functional effect\": 0.1682, \"times_seen\": 31.0}, {\"site\": 1112, \"mutant\": \"C\", \"escape\": -0.015804013210038357, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.0514, \"times_seen\": 8.0}, {\"site\": 1112, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1112, \"mutant\": \"L\", \"escape\": -0.011830620604986058, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.0997, \"times_seen\": 11.0}, {\"site\": 1112, \"mutant\": \"M\", \"escape\": 0.020570744713427243, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.5368, \"times_seen\": 1.0}, {\"site\": 1112, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -2.671, \"times_seen\": null}, {\"site\": 1112, \"mutant\": \"S\", \"escape\": -0.005659747407120021, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.4465, \"times_seen\": 1.0}, {\"site\": 1112, \"mutant\": \"T\", \"escape\": -0.31702182050427286, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": -1.0783, \"times_seen\": 40.0}, {\"site\": 1112, \"mutant\": \"V\", \"escape\": -0.2987687519361325, \"epitope\": \"epitope 1\", \"reference_site\": \"1115\", \"functional effect\": 0.0418, \"times_seen\": 50.0}, {\"site\": 1113, \"mutant\": \"A\", \"escape\": -0.03449681204540686, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": 0.1899, \"times_seen\": 25.0}, {\"site\": 1113, \"mutant\": \"I\", \"escape\": -0.06715875754104063, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": -1.9701, \"times_seen\": 23.0}, {\"site\": 1113, \"mutant\": \"N\", \"escape\": -0.024447303597624658, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": -0.2024, \"times_seen\": 67.0}, {\"site\": 1113, \"mutant\": \"S\", \"escape\": -1.1644394671614264, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": 0.2663, \"times_seen\": 25.0}, {\"site\": 1113, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1113, \"mutant\": \"V\", \"escape\": -0.04729448770916225, \"epitope\": \"epitope 1\", \"reference_site\": \"1116\", \"functional effect\": -1.6437, \"times_seen\": 8.0}, {\"site\": 1114, \"mutant\": \"*\", \"escape\": 2.1736794757254305, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -2.7794, \"times_seen\": 7.0}, {\"site\": 1114, \"mutant\": \"A\", \"escape\": 0.03956553402926758, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4808, \"times_seen\": 123.0}, {\"site\": 1114, \"mutant\": \"C\", \"escape\": -0.023823743666312673, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.3026, \"times_seen\": 56.0}, {\"site\": 1114, \"mutant\": \"D\", \"escape\": -0.08562794108615891, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.5538, \"times_seen\": 43.0}, {\"site\": 1114, \"mutant\": \"E\", \"escape\": 0.04283320204826064, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.3872, \"times_seen\": 45.0}, {\"site\": 1114, \"mutant\": \"F\", \"escape\": -0.0016512887796121755, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.7441, \"times_seen\": 46.0}, {\"site\": 1114, \"mutant\": \"G\", \"escape\": 0.4140919970983644, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.8119, \"times_seen\": 122.0}, {\"site\": 1114, \"mutant\": \"H\", \"escape\": -0.04733017116825584, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -1.1124, \"times_seen\": 33.0}, {\"site\": 1114, \"mutant\": \"I\", \"escape\": 0.014692541609133499, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.0388, \"times_seen\": 86.0}, {\"site\": 1114, \"mutant\": \"K\", \"escape\": 1.1072086344663896, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.2293, \"times_seen\": 20.0}, {\"site\": 1114, \"mutant\": \"L\", \"escape\": 0.02026854285297417, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.0931, \"times_seen\": 127.0}, {\"site\": 1114, \"mutant\": \"M\", \"escape\": 0.04370226875610458, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.1527, \"times_seen\": 39.0}, {\"site\": 1114, \"mutant\": \"N\", \"escape\": -0.04467623978468485, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.1167, \"times_seen\": 48.0}, {\"site\": 1114, \"mutant\": \"P\", \"escape\": -0.06138608384028917, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.5241, \"times_seen\": 67.0}, {\"site\": 1114, \"mutant\": \"Q\", \"escape\": 0.04680425647055465, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4067, \"times_seen\": 42.0}, {\"site\": 1114, \"mutant\": \"R\", \"escape\": 0.08278496344081658, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.2972, \"times_seen\": 175.0}, {\"site\": 1114, \"mutant\": \"S\", \"escape\": 0.005864764148652011, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4777, \"times_seen\": 146.0}, {\"site\": 1114, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1114, \"mutant\": \"V\", \"escape\": -0.010091569298443653, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": 0.284, \"times_seen\": 92.0}, {\"site\": 1114, \"mutant\": \"W\", \"escape\": -0.5546058027451557, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -1.7711, \"times_seen\": 18.0}, {\"site\": 1114, \"mutant\": \"Y\", \"escape\": 0.5165251036019701, \"epitope\": \"epitope 1\", \"reference_site\": \"1117\", \"functional effect\": -0.4969, \"times_seen\": 43.0}, {\"site\": 1115, \"mutant\": \"*\", \"escape\": -0.006721051495656816, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -2.9791, \"times_seen\": 2.0}, {\"site\": 1115, \"mutant\": \"A\", \"escape\": 0.24563265435599174, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -0.4849, \"times_seen\": 76.0}, {\"site\": 1115, \"mutant\": \"C\", \"escape\": -0.09085433385407121, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -0.8215, \"times_seen\": 31.0}, {\"site\": 1115, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1115, \"mutant\": \"E\", \"escape\": -2.04568102540524, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.1149, \"times_seen\": 53.0}, {\"site\": 1115, \"mutant\": \"F\", \"escape\": 0.05064443160092313, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.2446, \"times_seen\": 33.0}, {\"site\": 1115, \"mutant\": \"G\", \"escape\": -0.04744958563797121, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.0924, \"times_seen\": 95.0}, {\"site\": 1115, \"mutant\": \"H\", \"escape\": 0.7838179089863312, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3279, \"times_seen\": 30.0}, {\"site\": 1115, \"mutant\": \"I\", \"escape\": 0.03772578488419497, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.4012, \"times_seen\": 24.0}, {\"site\": 1115, \"mutant\": \"K\", \"escape\": -0.013313594470672574, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -0.4248, \"times_seen\": 9.0}, {\"site\": 1115, \"mutant\": \"L\", \"escape\": 0.3627024198590312, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.317, \"times_seen\": 73.0}, {\"site\": 1115, \"mutant\": \"M\", \"escape\": 0.9263008205638488, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.2603, \"times_seen\": 28.0}, {\"site\": 1115, \"mutant\": \"N\", \"escape\": -0.040390306634227664, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1115, \"mutant\": \"P\", \"escape\": -0.3712337767134414, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": -1.2134, \"times_seen\": 22.0}, {\"site\": 1115, \"mutant\": \"Q\", \"escape\": 0.08308338650332661, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3173, \"times_seen\": 19.0}, {\"site\": 1115, \"mutant\": \"R\", \"escape\": 0.0011393362783306568, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.2213, \"times_seen\": 77.0}, {\"site\": 1115, \"mutant\": \"S\", \"escape\": -0.04839951227414227, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.0417, \"times_seen\": 71.0}, {\"site\": 1115, \"mutant\": \"T\", \"escape\": -0.0003923107508873415, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3475, \"times_seen\": 41.0}, {\"site\": 1115, \"mutant\": \"V\", \"escape\": -0.8676838632496136, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3064, \"times_seen\": 92.0}, {\"site\": 1115, \"mutant\": \"W\", \"escape\": -0.017715016477642256, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1115, \"mutant\": \"Y\", \"escape\": 0.49589459177226336, \"epitope\": \"epitope 1\", \"reference_site\": \"1118\", \"functional effect\": 0.3516, \"times_seen\": 54.0}, {\"site\": 1116, \"mutant\": \"D\", \"escape\": 0.0063296926304560585, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -1.0119, \"times_seen\": 5.0}, {\"site\": 1116, \"mutant\": \"H\", \"escape\": 0.009445633179709376, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -0.995, \"times_seen\": 2.0}, {\"site\": 1116, \"mutant\": \"I\", \"escape\": -0.00068551161818991, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -2.0861, \"times_seen\": 2.0}, {\"site\": 1116, \"mutant\": \"K\", \"escape\": 0.010528957559449959, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -1.3586, \"times_seen\": 3.0}, {\"site\": 1116, \"mutant\": \"L\", \"escape\": -0.0103763055265647, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -1.6105, \"times_seen\": 3.0}, {\"site\": 1116, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1116, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -2.7984, \"times_seen\": null}, {\"site\": 1116, \"mutant\": \"S\", \"escape\": -0.013989248050994978, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -0.8817, \"times_seen\": 3.0}, {\"site\": 1116, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1119\", \"functional effect\": -3.2216, \"times_seen\": null}, {\"site\": 1117, \"mutant\": \"A\", \"escape\": 0.05187895905745806, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -0.5789, \"times_seen\": 14.0}, {\"site\": 1117, \"mutant\": \"F\", \"escape\": 0.017322086527864933, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -1.8992, \"times_seen\": 1.0}, {\"site\": 1117, \"mutant\": \"I\", \"escape\": -0.00020224037684462345, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -1.2336, \"times_seen\": 19.0}, {\"site\": 1117, \"mutant\": \"N\", \"escape\": -0.0017149493342146936, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -1.2726, \"times_seen\": 2.0}, {\"site\": 1117, \"mutant\": \"S\", \"escape\": 0.02529559397670948, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": -0.4278, \"times_seen\": 18.0}, {\"site\": 1117, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1120\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1118, \"mutant\": \"C\", \"escape\": -0.0062930287667968075, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -1.7205, \"times_seen\": 2.0}, {\"site\": 1118, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1118, \"mutant\": \"I\", \"escape\": -0.005959976707982559, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -1.0324, \"times_seen\": 2.0}, {\"site\": 1118, \"mutant\": \"L\", \"escape\": 0.007910346021461803, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -0.7748, \"times_seen\": 20.0}, {\"site\": 1118, \"mutant\": \"M\", \"escape\": -0.003652432323794765, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -0.6682, \"times_seen\": 1.0}, {\"site\": 1118, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -2.5171, \"times_seen\": null}, {\"site\": 1118, \"mutant\": \"V\", \"escape\": 0.0167082710041439, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": -1.1454, \"times_seen\": 4.0}, {\"site\": 1118, \"mutant\": \"Y\", \"escape\": -0.008617008323829747, \"epitope\": \"epitope 1\", \"reference_site\": \"1121\", \"functional effect\": 0.4125, \"times_seen\": 4.0}, {\"site\": 1119, \"mutant\": \"A\", \"escape\": 0.017250465251281818, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": 0.0042, \"times_seen\": 2.0}, {\"site\": 1119, \"mutant\": \"C\", \"escape\": -0.2420071707132147, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 1119, \"mutant\": \"E\", \"escape\": -0.007860159772934387, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.4705, \"times_seen\": 2.0}, {\"site\": 1119, \"mutant\": \"F\", \"escape\": 0.027531173114636272, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.004, \"times_seen\": 13.0}, {\"site\": 1119, \"mutant\": \"I\", \"escape\": -0.01783290024742604, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.163, \"times_seen\": 23.0}, {\"site\": 1119, \"mutant\": \"L\", \"escape\": -0.023080599141166603, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.4456, \"times_seen\": 34.0}, {\"site\": 1119, \"mutant\": \"M\", \"escape\": -0.03098384593753579, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": -0.1848, \"times_seen\": 20.0}, {\"site\": 1119, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1122\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1120, \"mutant\": \"A\", \"escape\": 0.02038094550009099, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": 0.2764, \"times_seen\": 11.0}, {\"site\": 1120, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1120, \"mutant\": \"F\", \"escape\": 0.00732733583054234, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -1.8543, \"times_seen\": 5.0}, {\"site\": 1120, \"mutant\": \"L\", \"escape\": -0.0020949076857590195, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -3.0152, \"times_seen\": 1.0}, {\"site\": 1120, \"mutant\": \"N\", \"escape\": -0.03332039739125926, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -1.1837, \"times_seen\": 16.0}, {\"site\": 1120, \"mutant\": \"P\", \"escape\": -0.0022984242611409004, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -2.4402, \"times_seen\": 1.0}, {\"site\": 1120, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1120, \"mutant\": \"T\", \"escape\": -0.031987602913407, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -0.0177, \"times_seen\": 17.0}, {\"site\": 1120, \"mutant\": \"Y\", \"escape\": 0.0115607929609165, \"epitope\": \"epitope 1\", \"reference_site\": \"1123\", \"functional effect\": -1.2961, \"times_seen\": 2.0}, {\"site\": 1121, \"mutant\": \"A\", \"escape\": -0.052300678370845795, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": 0.0116, \"times_seen\": 22.0}, {\"site\": 1121, \"mutant\": \"C\", \"escape\": -0.7740145888201835, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.3083, \"times_seen\": 52.0}, {\"site\": 1121, \"mutant\": \"D\", \"escape\": 0.16172053463005984, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.0186, \"times_seen\": 50.0}, {\"site\": 1121, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1121, \"mutant\": \"R\", \"escape\": -0.0272575141073047, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.2825, \"times_seen\": 17.0}, {\"site\": 1121, \"mutant\": \"S\", \"escape\": -0.01956448672929944, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": 0.1842, \"times_seen\": 71.0}, {\"site\": 1121, \"mutant\": \"V\", \"escape\": -0.00872202773899779, \"epitope\": \"epitope 1\", \"reference_site\": \"1124\", \"functional effect\": -0.8127, \"times_seen\": 16.0}, {\"site\": 1122, \"mutant\": \"D\", \"escape\": 0.006326577336505533, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.5036, \"times_seen\": 57.0}, {\"site\": 1122, \"mutant\": \"H\", \"escape\": 0.8787133989146987, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.4432, \"times_seen\": 21.0}, {\"site\": 1122, \"mutant\": \"K\", \"escape\": -0.20206678729512914, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.393, \"times_seen\": 79.0}, {\"site\": 1122, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1122, \"mutant\": \"S\", \"escape\": 0.9237539986419007, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -0.5408, \"times_seen\": 19.0}, {\"site\": 1122, \"mutant\": \"T\", \"escape\": -0.6625346779595886, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -1.063, \"times_seen\": 19.0}, {\"site\": 1122, \"mutant\": \"Y\", \"escape\": -0.018539282807927004, \"epitope\": \"epitope 1\", \"reference_site\": \"1125\", \"functional effect\": -1.0489, \"times_seen\": 28.0}, {\"site\": 1123, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -3.2598, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"F\", \"escape\": -0.0010756731978405285, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -0.724, \"times_seen\": 1.0}, {\"site\": 1123, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.9886, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"L\", \"escape\": -0.046448035813265315, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.2172, \"times_seen\": 4.0}, {\"site\": 1123, \"mutant\": \"R\", \"escape\": -0.004065835012213448, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.8921, \"times_seen\": 1.0}, {\"site\": 1123, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -3.1257, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1126\", \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 1124, \"mutant\": \"A\", \"escape\": 0.03647704630241214, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -0.1624, \"times_seen\": 11.0}, {\"site\": 1124, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1124, \"mutant\": \"E\", \"escape\": 0.055886271234981535, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.008, \"times_seen\": 34.0}, {\"site\": 1124, \"mutant\": \"G\", \"escape\": -0.086854051647887, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.1577, \"times_seen\": 65.0}, {\"site\": 1124, \"mutant\": \"H\", \"escape\": -0.4417765950808332, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": 0.02, \"times_seen\": 6.0}, {\"site\": 1124, \"mutant\": \"N\", \"escape\": -0.1386247180460331, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -0.24, \"times_seen\": 62.0}, {\"site\": 1124, \"mutant\": \"V\", \"escape\": -0.0075260886196888265, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -1.2044, \"times_seen\": 17.0}, {\"site\": 1124, \"mutant\": \"Y\", \"escape\": 0.05701396755503917, \"epitope\": \"epitope 1\", \"reference_site\": \"1127\", \"functional effect\": -0.3369, \"times_seen\": 58.0}, {\"site\": 1125, \"mutant\": \"A\", \"escape\": -0.02832379639831644, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": -0.1722, \"times_seen\": 10.0}, {\"site\": 1125, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": -2.7083, \"times_seen\": null}, {\"site\": 1125, \"mutant\": \"F\", \"escape\": -0.02231869737549088, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.2539, \"times_seen\": 37.0}, {\"site\": 1125, \"mutant\": \"I\", \"escape\": -0.09762182839847178, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.2408, \"times_seen\": 80.0}, {\"site\": 1125, \"mutant\": \"L\", \"escape\": 0.010299494826504276, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.3979, \"times_seen\": 29.0}, {\"site\": 1125, \"mutant\": \"M\", \"escape\": -0.024491637903871818, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.3325, \"times_seen\": 13.0}, {\"site\": 1125, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1128\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1126, \"mutant\": \"A\", \"escape\": 0.004081162659406173, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -1.7693, \"times_seen\": 2.0}, {\"site\": 1126, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.4619, \"times_seen\": null}, {\"site\": 1126, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 1126, \"mutant\": \"I\", \"escape\": -0.04613523601100747, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -0.1637, \"times_seen\": 40.0}, {\"site\": 1126, \"mutant\": \"L\", \"escape\": 0.004515810601603421, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.1342, \"times_seen\": 13.0}, {\"site\": 1126, \"mutant\": \"M\", \"escape\": -0.9742454271985538, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": -2.6109, \"times_seen\": 3.0}, {\"site\": 1126, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1129\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1127, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -3.0159, \"times_seen\": null}, {\"site\": 1127, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1127, \"mutant\": \"L\", \"escape\": -0.0040949305633199845, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -0.7439, \"times_seen\": 25.0}, {\"site\": 1127, \"mutant\": \"M\", \"escape\": 0.5401931547611678, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -0.1114, \"times_seen\": 63.0}, {\"site\": 1127, \"mutant\": \"N\", \"escape\": 0.007513164901658378, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.8813, \"times_seen\": 1.0}, {\"site\": 1127, \"mutant\": \"S\", \"escape\": 0.0025269973049802763, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.3624, \"times_seen\": 1.0}, {\"site\": 1127, \"mutant\": \"T\", \"escape\": -0.011420145191681174, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.3744, \"times_seen\": 21.0}, {\"site\": 1127, \"mutant\": \"V\", \"escape\": 0.6239962934657023, \"epitope\": \"epitope 1\", \"reference_site\": \"1130\", \"functional effect\": -1.21, \"times_seen\": 45.0}, {\"site\": 1128, \"mutant\": \"A\", \"escape\": -0.12365214542250806, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -1.6676, \"times_seen\": 30.0}, {\"site\": 1128, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -2.5563, \"times_seen\": null}, {\"site\": 1128, \"mutant\": \"D\", \"escape\": -0.007749886452931966, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -0.4444, \"times_seen\": 26.0}, {\"site\": 1128, \"mutant\": \"E\", \"escape\": -0.000907967442773604, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -1.1128, \"times_seen\": 15.0}, {\"site\": 1128, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1128, \"mutant\": \"R\", \"escape\": -0.0033989107292785735, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -2.0817, \"times_seen\": 1.0}, {\"site\": 1128, \"mutant\": \"S\", \"escape\": -0.002835253048258343, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -1.5422, \"times_seen\": 2.0}, {\"site\": 1128, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1131\", \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 1129, \"mutant\": \"F\", \"escape\": -0.02543674681515306, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.7658, \"times_seen\": 11.0}, {\"site\": 1129, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1129, \"mutant\": \"L\", \"escape\": -0.010130122883343626, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -0.4432, \"times_seen\": 16.0}, {\"site\": 1129, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -0.3274, \"times_seen\": null}, {\"site\": 1129, \"mutant\": \"N\", \"escape\": -0.0027317124929354913, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.5141, \"times_seen\": 1.0}, {\"site\": 1129, \"mutant\": \"T\", \"escape\": 0.02796508917641193, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.5754, \"times_seen\": 10.0}, {\"site\": 1129, \"mutant\": \"V\", \"escape\": 0.10814666455914135, \"epitope\": \"epitope 1\", \"reference_site\": \"1132\", \"functional effect\": -1.005, \"times_seen\": 27.0}, {\"site\": 1130, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"A\", \"escape\": -0.027463738326079457, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.0239, \"times_seen\": 24.0}, {\"site\": 1130, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.2697, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"F\", \"escape\": 0.2694556436915688, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.8393, \"times_seen\": 37.0}, {\"site\": 1130, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -2.0997, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"I\", \"escape\": -0.0034330359143528084, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": 0.0819, \"times_seen\": 20.0}, {\"site\": 1130, \"mutant\": \"L\", \"escape\": -0.6913471313149022, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.4561, \"times_seen\": 48.0}, {\"site\": 1130, \"mutant\": \"M\", \"escape\": -0.023656661348757005, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": -0.2285, \"times_seen\": 22.0}, {\"site\": 1130, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1133\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1131, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1131, \"mutant\": \"D\", \"escape\": -0.023345175076561833, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.1632, \"times_seen\": 23.0}, {\"site\": 1131, \"mutant\": \"H\", \"escape\": 0.023610750894782394, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.2539, \"times_seen\": 18.0}, {\"site\": 1131, \"mutant\": \"I\", \"escape\": -0.011477050582555173, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": -0.4037, \"times_seen\": 1.0}, {\"site\": 1131, \"mutant\": \"K\", \"escape\": 0.018162204692138507, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.3876, \"times_seen\": 8.0}, {\"site\": 1131, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1131, \"mutant\": \"S\", \"escape\": -0.020043195926529936, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.1915, \"times_seen\": 19.0}, {\"site\": 1131, \"mutant\": \"Y\", \"escape\": -0.038449398303122315, \"epitope\": \"epitope 1\", \"reference_site\": \"1134\", \"functional effect\": 0.0579, \"times_seen\": 26.0}, {\"site\": 1132, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1132, \"mutant\": \"D\", \"escape\": -0.06989238592331765, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": -0.2686, \"times_seen\": 54.0}, {\"site\": 1132, \"mutant\": \"G\", \"escape\": -0.009085583126593707, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.3392, \"times_seen\": 1.0}, {\"site\": 1132, \"mutant\": \"H\", \"escape\": 0.1770115515044395, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.3287, \"times_seen\": 47.0}, {\"site\": 1132, \"mutant\": \"I\", \"escape\": -0.09319584123871258, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.4444, \"times_seen\": 34.0}, {\"site\": 1132, \"mutant\": \"K\", \"escape\": -0.0023003100465523226, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.1278, \"times_seen\": 29.0}, {\"site\": 1132, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1132, \"mutant\": \"S\", \"escape\": -0.07387000227692454, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.0169, \"times_seen\": 30.0}, {\"site\": 1132, \"mutant\": \"Y\", \"escape\": -0.004850589772817329, \"epitope\": \"epitope 1\", \"reference_site\": \"1135\", \"functional effect\": 0.4444, \"times_seen\": 40.0}, {\"site\": 1133, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1133, \"mutant\": \"A\", \"escape\": -0.04469284512076662, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.2773, \"times_seen\": 28.0}, {\"site\": 1133, \"mutant\": \"I\", \"escape\": 0.041397691164581, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.3854, \"times_seen\": 73.0}, {\"site\": 1133, \"mutant\": \"K\", \"escape\": -0.03418106407397836, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.1615, \"times_seen\": 30.0}, {\"site\": 1133, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1133, \"mutant\": \"Q\", \"escape\": -0.011034795960166962, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.1291, \"times_seen\": 23.0}, {\"site\": 1133, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.8711, \"times_seen\": null}, {\"site\": 1133, \"mutant\": \"S\", \"escape\": -0.09074071368401564, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.3655, \"times_seen\": 28.0}, {\"site\": 1133, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1136\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1134, \"mutant\": \"A\", \"escape\": -0.004306696799157166, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": -0.6368, \"times_seen\": 1.0}, {\"site\": 1134, \"mutant\": \"F\", \"escape\": -0.007753898508800693, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": -0.3921, \"times_seen\": 26.0}, {\"site\": 1134, \"mutant\": \"G\", \"escape\": -0.004165538108186292, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1134, \"mutant\": \"I\", \"escape\": -0.07583010117646603, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": 0.1507, \"times_seen\": 32.0}, {\"site\": 1134, \"mutant\": \"M\", \"escape\": -0.020313375513360307, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": -0.5631, \"times_seen\": 11.0}, {\"site\": 1134, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1137\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1135, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -2.7638, \"times_seen\": null}, {\"site\": 1135, \"mutant\": \"C\", \"escape\": 0.04144558041482253, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -1.7593, \"times_seen\": 2.0}, {\"site\": 1135, \"mutant\": \"D\", \"escape\": 0.03662519461595093, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -0.6748, \"times_seen\": 1.0}, {\"site\": 1135, \"mutant\": \"F\", \"escape\": 0.03782790896565347, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": 0.2701, \"times_seen\": 31.0}, {\"site\": 1135, \"mutant\": \"H\", \"escape\": 0.09476114725951269, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -0.3486, \"times_seen\": 28.0}, {\"site\": 1135, \"mutant\": \"L\", \"escape\": -0.011634877245675301, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": 0.4337, \"times_seen\": 16.0}, {\"site\": 1135, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": -1.1135, \"times_seen\": null}, {\"site\": 1135, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1138\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1136, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1136, \"mutant\": \"A\", \"escape\": -0.018005477942949013, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.913, \"times_seen\": 14.0}, {\"site\": 1136, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1136, \"mutant\": \"E\", \"escape\": -1.5569292966759796, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -2.1192, \"times_seen\": 15.0}, {\"site\": 1136, \"mutant\": \"G\", \"escape\": 0.02420093078348323, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.0282, \"times_seen\": 26.0}, {\"site\": 1136, \"mutant\": \"H\", \"escape\": 0.09001700020751204, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -0.2512, \"times_seen\": 63.0}, {\"site\": 1136, \"mutant\": \"I\", \"escape\": 0.0037302833547774666, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.4491, \"times_seen\": 12.0}, {\"site\": 1136, \"mutant\": \"N\", \"escape\": -0.24524901016198647, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.3553, \"times_seen\": 87.0}, {\"site\": 1136, \"mutant\": \"V\", \"escape\": 0.0027049469461672892, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": -1.6317, \"times_seen\": 9.0}, {\"site\": 1136, \"mutant\": \"Y\", \"escape\": -0.012404840933798674, \"epitope\": \"epitope 1\", \"reference_site\": \"1139\", \"functional effect\": 0.2, \"times_seen\": 60.0}, {\"site\": 1137, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1137, \"mutant\": \"A\", \"escape\": 0.02045299354438528, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.4051, \"times_seen\": 17.0}, {\"site\": 1137, \"mutant\": \"L\", \"escape\": 0.007354209967708645, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.4109, \"times_seen\": 3.0}, {\"site\": 1137, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1137, \"mutant\": \"Q\", \"escape\": 0.016586197861847833, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.2334, \"times_seen\": 5.0}, {\"site\": 1137, \"mutant\": \"S\", \"escape\": 0.3069104596649082, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.397, \"times_seen\": 21.0}, {\"site\": 1137, \"mutant\": \"T\", \"escape\": 0.03055860467195135, \"epitope\": \"epitope 1\", \"reference_site\": \"1140\", \"functional effect\": 0.3651, \"times_seen\": 9.0}, {\"site\": 1138, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1138, \"mutant\": \"F\", \"escape\": 0.026464901314931483, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.4315, \"times_seen\": 83.0}, {\"site\": 1138, \"mutant\": \"H\", \"escape\": 0.022052034869835827, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.169, \"times_seen\": 1.0}, {\"site\": 1138, \"mutant\": \"I\", \"escape\": 0.007471616982065487, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.965, \"times_seen\": 4.0}, {\"site\": 1138, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1138, \"mutant\": \"P\", \"escape\": -0.004872284560064717, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -2.5233, \"times_seen\": 2.0}, {\"site\": 1138, \"mutant\": \"R\", \"escape\": -0.0020971969497386774, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": 0.1736, \"times_seen\": 1.0}, {\"site\": 1138, \"mutant\": \"S\", \"escape\": 0.06052606141357901, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.6613, \"times_seen\": 17.0}, {\"site\": 1138, \"mutant\": \"W\", \"escape\": -0.010159166415817827, \"epitope\": \"epitope 1\", \"reference_site\": \"1141\", \"functional effect\": -0.1245, \"times_seen\": 20.0}, {\"site\": 1139, \"mutant\": \"*\", \"escape\": -0.01171443760831398, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -2.2672, \"times_seen\": 1.0}, {\"site\": 1139, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1139, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -1.9059, \"times_seen\": null}, {\"site\": 1139, \"mutant\": \"K\", \"escape\": -0.0075716225701105595, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -0.0954, \"times_seen\": 2.0}, {\"site\": 1139, \"mutant\": \"L\", \"escape\": -1.1079079888248669, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -0.777, \"times_seen\": 41.0}, {\"site\": 1139, \"mutant\": \"M\", \"escape\": 0.01084855446870885, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": -0.888, \"times_seen\": 18.0}, {\"site\": 1139, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1139, \"mutant\": \"R\", \"escape\": -0.15515356234841027, \"epitope\": \"epitope 1\", \"reference_site\": \"1142\", \"functional effect\": 0.397, \"times_seen\": 20.0}, {\"site\": 1140, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1140, \"mutant\": \"A\", \"escape\": 0.005583479201171228, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1140, \"mutant\": \"H\", \"escape\": -0.03753026935099008, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1140, \"mutant\": \"L\", \"escape\": 0.13369829560385768, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.394, \"times_seen\": 78.0}, {\"site\": 1140, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1140, \"mutant\": \"S\", \"escape\": 0.7237305629146471, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 1140, \"mutant\": \"T\", \"escape\": 0.014549472775489281, \"epitope\": \"epitope 1\", \"reference_site\": \"1143\", \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 1141, \"mutant\": \"*\", \"escape\": -0.01174517954437637, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": -1.4739, \"times_seen\": 3.0}, {\"site\": 1141, \"mutant\": \"A\", \"escape\": -0.030748523782705355, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.2804, \"times_seen\": 33.0}, {\"site\": 1141, \"mutant\": \"D\", \"escape\": 0.8590057409235955, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": -0.8182, \"times_seen\": 55.0}, {\"site\": 1141, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1141, \"mutant\": \"G\", \"escape\": 0.04169668869856995, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": -0.2457, \"times_seen\": 1.0}, {\"site\": 1141, \"mutant\": \"K\", \"escape\": -0.022381298559596318, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.4317, \"times_seen\": 107.0}, {\"site\": 1141, \"mutant\": \"Q\", \"escape\": 0.4664039934233336, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.4266, \"times_seen\": 30.0}, {\"site\": 1141, \"mutant\": \"S\", \"escape\": 0.030769664863175443, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.312, \"times_seen\": 20.0}, {\"site\": 1141, \"mutant\": \"V\", \"escape\": -0.019312766601268353, \"epitope\": \"epitope 1\", \"reference_site\": \"1144\", \"functional effect\": 0.3085, \"times_seen\": 51.0}, {\"site\": 1142, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1142, \"mutant\": \"M\", \"escape\": 0.03216073225916313, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -0.6534, \"times_seen\": 6.0}, {\"site\": 1142, \"mutant\": \"P\", \"escape\": -0.0076691230275089655, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -2.2462, \"times_seen\": 1.0}, {\"site\": 1142, \"mutant\": \"Q\", \"escape\": -0.0032444693799040508, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -1.3835, \"times_seen\": 2.0}, {\"site\": 1142, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -1.545, \"times_seen\": null}, {\"site\": 1142, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1145\", \"functional effect\": -2.4853, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"A\", \"escape\": -0.02653156258579034, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": 0.0804, \"times_seen\": 16.0}, {\"site\": 1143, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"E\", \"escape\": 0.0451180214542415, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.0953, \"times_seen\": 83.0}, {\"site\": 1143, \"mutant\": \"G\", \"escape\": 1.0988399020802044, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -1.1339, \"times_seen\": 18.0}, {\"site\": 1143, \"mutant\": \"H\", \"escape\": 0.0484815663289507, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.3235, \"times_seen\": 50.0}, {\"site\": 1143, \"mutant\": \"N\", \"escape\": 0.05298107511934485, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.2148, \"times_seen\": 67.0}, {\"site\": 1143, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -0.8795, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"Y\", \"escape\": -0.028451971137945252, \"epitope\": \"epitope 1\", \"reference_site\": \"1146\", \"functional effect\": -1.1626, \"times_seen\": 49.0}, {\"site\": 1144, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1144, \"mutant\": \"A\", \"escape\": -0.03373758627181529, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": 0.4273, \"times_seen\": 22.0}, {\"site\": 1144, \"mutant\": \"F\", \"escape\": -0.006445333239119221, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -1.1498, \"times_seen\": 4.0}, {\"site\": 1144, \"mutant\": \"L\", \"escape\": 0.3330680053962839, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -0.5645, \"times_seen\": 34.0}, {\"site\": 1144, \"mutant\": \"P\", \"escape\": 0.04268429562606621, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -2.038, \"times_seen\": 9.0}, {\"site\": 1144, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1144, \"mutant\": \"T\", \"escape\": 0.010239735165838239, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -0.2766, \"times_seen\": 18.0}, {\"site\": 1144, \"mutant\": \"Y\", \"escape\": -0.0012742936950438503, \"epitope\": \"epitope 1\", \"reference_site\": \"1147\", \"functional effect\": -1.213, \"times_seen\": 3.0}, {\"site\": 1145, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1145, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1145, \"mutant\": \"I\", \"escape\": -0.006157795694530244, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -0.392, \"times_seen\": 3.0}, {\"site\": 1145, \"mutant\": \"L\", \"escape\": -0.028142645780063535, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -0.3991, \"times_seen\": 27.0}, {\"site\": 1145, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -2.774, \"times_seen\": null}, {\"site\": 1145, \"mutant\": \"V\", \"escape\": 0.011096437739792622, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": -0.2699, \"times_seen\": 2.0}, {\"site\": 1145, \"mutant\": \"Y\", \"escape\": -0.00459837115315152, \"epitope\": \"epitope 1\", \"reference_site\": \"1148\", \"functional effect\": 0.1984, \"times_seen\": 1.0}, {\"site\": 1146, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1146, \"mutant\": \"E\", \"escape\": -0.0085946516469714, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -1.6481, \"times_seen\": 3.0}, {\"site\": 1146, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1146, \"mutant\": \"M\", \"escape\": -0.1435471880220337, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -0.5776, \"times_seen\": 78.0}, {\"site\": 1146, \"mutant\": \"N\", \"escape\": 0.025713108608885878, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -1.8489, \"times_seen\": 25.0}, {\"site\": 1146, \"mutant\": \"Q\", \"escape\": -0.0032546956025766836, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -0.9531, \"times_seen\": 1.0}, {\"site\": 1146, \"mutant\": \"R\", \"escape\": -0.00822012455073083, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -0.0919, \"times_seen\": 57.0}, {\"site\": 1146, \"mutant\": \"T\", \"escape\": -0.0021751105748272384, \"epitope\": \"epitope 1\", \"reference_site\": \"1149\", \"functional effect\": -2.3638, \"times_seen\": 1.0}, {\"site\": 1147, \"mutant\": \"*\", \"escape\": -0.004651217212202843, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -2.9546, \"times_seen\": 1.0}, {\"site\": 1147, \"mutant\": \"A\", \"escape\": 0.03908343818376579, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.4162, \"times_seen\": 9.0}, {\"site\": 1147, \"mutant\": \"D\", \"escape\": -0.20620935249106512, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.0334, \"times_seen\": 75.0}, {\"site\": 1147, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1147, \"mutant\": \"G\", \"escape\": -0.03579675727239004, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.078, \"times_seen\": 24.0}, {\"site\": 1147, \"mutant\": \"K\", \"escape\": -0.5884081573251988, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.2965, \"times_seen\": 54.0}, {\"site\": 1147, \"mutant\": \"Q\", \"escape\": -0.01971794849861865, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.1427, \"times_seen\": 30.0}, {\"site\": 1147, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1147, \"mutant\": \"V\", \"escape\": -0.029838334076170214, \"epitope\": \"epitope 1\", \"reference_site\": \"1150\", \"functional effect\": -0.6488, \"times_seen\": 29.0}, {\"site\": 1148, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": -2.9483, \"times_seen\": null}, {\"site\": 1148, \"mutant\": \"D\", \"escape\": 0.14509816503536405, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": 0.3094, \"times_seen\": 55.0}, {\"site\": 1148, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1148, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 1148, \"mutant\": \"K\", \"escape\": -0.01075731957540914, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": -0.8579, \"times_seen\": 46.0}, {\"site\": 1148, \"mutant\": \"Q\", \"escape\": 0.010884727096549265, \"epitope\": \"epitope 1\", \"reference_site\": \"1151\", \"functional effect\": -0.3312, \"times_seen\": 6.0}, {\"site\": 1149, \"mutant\": \"F\", \"escape\": 0.016898128159156842, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -0.2535, \"times_seen\": 3.0}, {\"site\": 1149, \"mutant\": \"I\", \"escape\": -0.0022854334529627553, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -0.1685, \"times_seen\": 5.0}, {\"site\": 1149, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1149, \"mutant\": \"M\", \"escape\": -0.008098792208693844, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -0.0935, \"times_seen\": 3.0}, {\"site\": 1149, \"mutant\": \"P\", \"escape\": 0.007242843227820657, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -2.4196, \"times_seen\": 2.0}, {\"site\": 1149, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 1149, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -2.1789, \"times_seen\": null}, {\"site\": 1149, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1152\", \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 1150, \"mutant\": \"A\", \"escape\": -0.12907009939298408, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": -0.2024, \"times_seen\": 36.0}, {\"site\": 1150, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1150, \"mutant\": \"E\", \"escape\": 0.006334403458800147, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.1902, \"times_seen\": 26.0}, {\"site\": 1150, \"mutant\": \"G\", \"escape\": -0.052380590114421276, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": -0.1208, \"times_seen\": 48.0}, {\"site\": 1150, \"mutant\": \"H\", \"escape\": -0.017979818097456874, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.2916, \"times_seen\": 58.0}, {\"site\": 1150, \"mutant\": \"N\", \"escape\": -0.005535020980995122, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.0225, \"times_seen\": 43.0}, {\"site\": 1150, \"mutant\": \"S\", \"escape\": 0.006356468304753856, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.1762, \"times_seen\": 1.0}, {\"site\": 1150, \"mutant\": \"V\", \"escape\": 0.0027975841948281346, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.4035, \"times_seen\": 12.0}, {\"site\": 1150, \"mutant\": \"Y\", \"escape\": -0.2665501771455987, \"epitope\": \"epitope 1\", \"reference_site\": \"1153\", \"functional effect\": 0.3282, \"times_seen\": 52.0}, {\"site\": 1151, \"mutant\": \"E\", \"escape\": 0.03553778964640094, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3145, \"times_seen\": 32.0}, {\"site\": 1151, \"mutant\": \"G\", \"escape\": -8.89216896729785e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1151, \"mutant\": \"I\", \"escape\": 0.022904538126172068, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3651, \"times_seen\": 36.0}, {\"site\": 1151, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1151, \"mutant\": \"N\", \"escape\": -0.055713456377003964, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.2984, \"times_seen\": 29.0}, {\"site\": 1151, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1151, \"mutant\": \"R\", \"escape\": -0.02309459457291853, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.3142, \"times_seen\": 15.0}, {\"site\": 1151, \"mutant\": \"T\", \"escape\": 0.003808156796519525, \"epitope\": \"epitope 1\", \"reference_site\": \"1154\", \"functional effect\": 0.4344, \"times_seen\": 16.0}, {\"site\": 1152, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -2.0697, \"times_seen\": null}, {\"site\": 1152, \"mutant\": \"C\", \"escape\": 0.008718855586173021, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -1.3143, \"times_seen\": 3.0}, {\"site\": 1152, \"mutant\": \"F\", \"escape\": 0.03821527807804849, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -0.2061, \"times_seen\": 38.0}, {\"site\": 1152, \"mutant\": \"H\", \"escape\": 0.6420516839049628, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": 0.3612, \"times_seen\": 83.0}, {\"site\": 1152, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": -0.7103, \"times_seen\": null}, {\"site\": 1152, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1155\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1153, \"mutant\": \"C\", \"escape\": -0.0023453717817912673, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 1153, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1153, \"mutant\": \"I\", \"escape\": -0.003891138739741403, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -0.2959, \"times_seen\": 1.0}, {\"site\": 1153, \"mutant\": \"L\", \"escape\": -0.015832936533055193, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -0.3184, \"times_seen\": 47.0}, {\"site\": 1153, \"mutant\": \"S\", \"escape\": 0.0346120799390487, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -0.0529, \"times_seen\": 2.0}, {\"site\": 1153, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": -2.8933, \"times_seen\": null}, {\"site\": 1153, \"mutant\": \"Y\", \"escape\": -0.0013545985782656728, \"epitope\": \"epitope 1\", \"reference_site\": \"1156\", \"functional effect\": 0.4067, \"times_seen\": 1.0}, {\"site\": 1154, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -2.8081, \"times_seen\": null}, {\"site\": 1154, \"mutant\": \"E\", \"escape\": -0.00010344544789825604, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3787, \"times_seen\": 43.0}, {\"site\": 1154, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1154, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1154, \"mutant\": \"M\", \"escape\": -0.09257742907057229, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3254, \"times_seen\": 78.0}, {\"site\": 1154, \"mutant\": \"N\", \"escape\": -0.1991947356572608, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3259, \"times_seen\": 79.0}, {\"site\": 1154, \"mutant\": \"R\", \"escape\": 0.05402537060081817, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.3548, \"times_seen\": 54.0}, {\"site\": 1154, \"mutant\": \"T\", \"escape\": -0.03238231611302292, \"epitope\": \"epitope 1\", \"reference_site\": \"1157\", \"functional effect\": -0.2959, \"times_seen\": 31.0}, {\"site\": 1155, \"mutant\": \"D\", \"escape\": -0.06743993475738042, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.6253, \"times_seen\": 28.0}, {\"site\": 1155, \"mutant\": \"H\", \"escape\": -0.2169103351166267, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.0871, \"times_seen\": 31.0}, {\"site\": 1155, \"mutant\": \"I\", \"escape\": -0.01133762565191097, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1155, \"mutant\": \"K\", \"escape\": 0.19480863393353573, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.656, \"times_seen\": 25.0}, {\"site\": 1155, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1155, \"mutant\": \"S\", \"escape\": 0.5776720061629541, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.6445, \"times_seen\": 85.0}, {\"site\": 1155, \"mutant\": \"T\", \"escape\": -0.006919435840734479, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.5265, \"times_seen\": 27.0}, {\"site\": 1155, \"mutant\": \"Y\", \"escape\": -0.003070113950579848, \"epitope\": \"epitope 1\", \"reference_site\": \"1158\", \"functional effect\": -0.2548, \"times_seen\": 19.0}, {\"site\": 1156, \"mutant\": \"H\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1156, \"mutant\": \"L\", \"escape\": 0.38586655342431025, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": -0.3597, \"times_seen\": 28.0}, {\"site\": 1156, \"mutant\": \"N\", \"escape\": -0.10790961506294472, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.152, \"times_seen\": 18.0}, {\"site\": 1156, \"mutant\": \"Q\", \"escape\": 0.019129854417562295, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.2068, \"times_seen\": 24.0}, {\"site\": 1156, \"mutant\": \"R\", \"escape\": -1.946348917780808, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.0721, \"times_seen\": 43.0}, {\"site\": 1156, \"mutant\": \"Y\", \"escape\": -0.15687961068742504, \"epitope\": \"epitope 1\", \"reference_site\": \"1159\", \"functional effect\": 0.0425, \"times_seen\": 61.0}, {\"site\": 1157, \"mutant\": \"A\", \"escape\": 0.033913403823767424, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.78, \"times_seen\": 36.0}, {\"site\": 1157, \"mutant\": \"I\", \"escape\": 0.005803123798650437, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.7148, \"times_seen\": 5.0}, {\"site\": 1157, \"mutant\": \"N\", \"escape\": -0.0071942757806918115, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.2803, \"times_seen\": 8.0}, {\"site\": 1157, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -2.9246, \"times_seen\": null}, {\"site\": 1157, \"mutant\": \"S\", \"escape\": -0.0017489770861535891, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": -0.1738, \"times_seen\": 2.0}, {\"site\": 1157, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1160\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1158, \"mutant\": \"A\", \"escape\": -0.39428497066070284, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.2119, \"times_seen\": 15.0}, {\"site\": 1158, \"mutant\": \"C\", \"escape\": -0.001993831302099676, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.1953, \"times_seen\": 1.0}, {\"site\": 1158, \"mutant\": \"G\", \"escape\": 0.0016458892241102932, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.0086, \"times_seen\": 5.0}, {\"site\": 1158, \"mutant\": \"I\", \"escape\": -0.009481943635794536, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.9118, \"times_seen\": 4.0}, {\"site\": 1158, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -1.62, \"times_seen\": null}, {\"site\": 1158, \"mutant\": \"L\", \"escape\": 0.007069435890281701, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.2703, \"times_seen\": 9.0}, {\"site\": 1158, \"mutant\": \"N\", \"escape\": -0.003095751515381652, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.0661, \"times_seen\": 17.0}, {\"site\": 1158, \"mutant\": \"P\", \"escape\": -0.008539352046049081, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.572, \"times_seen\": 8.0}, {\"site\": 1158, \"mutant\": \"R\", \"escape\": 0.018765836744676904, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.1152, \"times_seen\": 6.0}, {\"site\": 1158, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1158, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1161\", \"functional effect\": -0.0525, \"times_seen\": null}, {\"site\": 1159, \"mutant\": \"A\", \"escape\": 0.007235114028580854, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.0636, \"times_seen\": 33.0}, {\"site\": 1159, \"mutant\": \"H\", \"escape\": 0.011175950730651982, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.0107, \"times_seen\": 6.0}, {\"site\": 1159, \"mutant\": \"L\", \"escape\": -0.5262432450016431, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.1481, \"times_seen\": 35.0}, {\"site\": 1159, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1159, \"mutant\": \"Q\", \"escape\": 0.3739980123426443, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.0636, \"times_seen\": 43.0}, {\"site\": 1159, \"mutant\": \"R\", \"escape\": -0.2977780768872039, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": 0.2868, \"times_seen\": 14.0}, {\"site\": 1159, \"mutant\": \"S\", \"escape\": 0.07610362246903742, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.0167, \"times_seen\": 26.0}, {\"site\": 1159, \"mutant\": \"T\", \"escape\": -0.13481661874403916, \"epitope\": \"epitope 1\", \"reference_site\": \"1162\", \"functional effect\": -0.0225, \"times_seen\": 52.0}, {\"site\": 1160, \"mutant\": \"*\", \"escape\": 0.055042756858864665, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -2.8361, \"times_seen\": 14.0}, {\"site\": 1160, \"mutant\": \"-\", \"escape\": -0.006135026474981777, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1160, \"mutant\": \"A\", \"escape\": -0.914119469510439, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.1275, \"times_seen\": 192.0}, {\"site\": 1160, \"mutant\": \"C\", \"escape\": 0.017812377473361455, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -1.0516, \"times_seen\": 42.0}, {\"site\": 1160, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1160, \"mutant\": \"E\", \"escape\": -0.2370160820619471, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0843, \"times_seen\": 153.0}, {\"site\": 1160, \"mutant\": \"F\", \"escape\": -1.143489348881023, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.7344, \"times_seen\": 46.0}, {\"site\": 1160, \"mutant\": \"G\", \"escape\": -0.07370385697937579, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0435, \"times_seen\": 209.0}, {\"site\": 1160, \"mutant\": \"H\", \"escape\": 0.011964834611263556, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.3688, \"times_seen\": 136.0}, {\"site\": 1160, \"mutant\": \"I\", \"escape\": -0.24935770175944832, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2986, \"times_seen\": 68.0}, {\"site\": 1160, \"mutant\": \"K\", \"escape\": -0.08975782411525184, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2916, \"times_seen\": 72.0}, {\"site\": 1160, \"mutant\": \"L\", \"escape\": -0.0992867604936419, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.4725, \"times_seen\": 103.0}, {\"site\": 1160, \"mutant\": \"M\", \"escape\": -0.008975051067610852, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.3362, \"times_seen\": 38.0}, {\"site\": 1160, \"mutant\": \"N\", \"escape\": -0.017804823604711265, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.074, \"times_seen\": 180.0}, {\"site\": 1160, \"mutant\": \"P\", \"escape\": 0.31386718048059736, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0814, \"times_seen\": 112.0}, {\"site\": 1160, \"mutant\": \"Q\", \"escape\": -0.04619129300160226, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.204, \"times_seen\": 38.0}, {\"site\": 1160, \"mutant\": \"R\", \"escape\": -0.033589178434947936, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2112, \"times_seen\": 122.0}, {\"site\": 1160, \"mutant\": \"S\", \"escape\": 0.020121585502766295, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.0991, \"times_seen\": 157.0}, {\"site\": 1160, \"mutant\": \"T\", \"escape\": 0.13761160621104115, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.1426, \"times_seen\": 99.0}, {\"site\": 1160, \"mutant\": \"V\", \"escape\": 0.2963572444526582, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.2857, \"times_seen\": 123.0}, {\"site\": 1160, \"mutant\": \"W\", \"escape\": 0.10307147366822457, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.7356, \"times_seen\": 53.0}, {\"site\": 1160, \"mutant\": \"Y\", \"escape\": 0.21535924225908845, \"epitope\": \"epitope 1\", \"reference_site\": \"1163\", \"functional effect\": -0.5144, \"times_seen\": 141.0}, {\"site\": 1161, \"mutant\": \"-\", \"escape\": -0.005919297607039204, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1161, \"mutant\": \"A\", \"escape\": -0.007365920075148653, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.0882, \"times_seen\": 10.0}, {\"site\": 1161, \"mutant\": \"E\", \"escape\": -0.012599617258495526, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.2839, \"times_seen\": 2.0}, {\"site\": 1161, \"mutant\": \"F\", \"escape\": -0.025832503564363878, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.1568, \"times_seen\": 12.0}, {\"site\": 1161, \"mutant\": \"I\", \"escape\": 0.04530747491920206, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.149, \"times_seen\": 18.0}, {\"site\": 1161, \"mutant\": \"L\", \"escape\": -0.0015393103399129688, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": -0.0091, \"times_seen\": 9.0}, {\"site\": 1161, \"mutant\": \"M\", \"escape\": -0.1611244338919158, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.0547, \"times_seen\": 14.0}, {\"site\": 1161, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1161, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1164\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1162, \"mutant\": \"-\", \"escape\": -0.0076349817590440705, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1162, \"mutant\": \"A\", \"escape\": -0.5372176610332049, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": 0.0419, \"times_seen\": 33.0}, {\"site\": 1162, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1162, \"mutant\": \"E\", \"escape\": 0.000954590980109858, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.0693, \"times_seen\": 73.0}, {\"site\": 1162, \"mutant\": \"G\", \"escape\": -0.0557106540245873, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": 0.0946, \"times_seen\": 173.0}, {\"site\": 1162, \"mutant\": \"H\", \"escape\": -0.0728175131945896, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.0328, \"times_seen\": 21.0}, {\"site\": 1162, \"mutant\": \"N\", \"escape\": -0.04913778431198768, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.0022, \"times_seen\": 56.0}, {\"site\": 1162, \"mutant\": \"V\", \"escape\": -0.056038350535373045, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.4093, \"times_seen\": 31.0}, {\"site\": 1162, \"mutant\": \"Y\", \"escape\": 0.0007322330596075026, \"epitope\": \"epitope 1\", \"reference_site\": \"1165\", \"functional effect\": -0.294, \"times_seen\": 17.0}, {\"site\": 1163, \"mutant\": \"-\", \"escape\": -0.013767112052292077, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.35, \"times_seen\": 1.0}, {\"site\": 1163, \"mutant\": \"F\", \"escape\": -0.006877964435028734, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": 0.0174, \"times_seen\": 7.0}, {\"site\": 1163, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1163, \"mutant\": \"M\", \"escape\": 0.0012881254311648519, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": 0.0125, \"times_seen\": 8.0}, {\"site\": 1163, \"mutant\": \"P\", \"escape\": -1.0919598395634433, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.0089, \"times_seen\": 41.0}, {\"site\": 1163, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.1077, \"times_seen\": null}, {\"site\": 1163, \"mutant\": \"R\", \"escape\": -0.014878123591770293, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -0.9381, \"times_seen\": 2.0}, {\"site\": 1163, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1166\", \"functional effect\": -3.2137, \"times_seen\": null}, {\"site\": 1164, \"mutant\": \"*\", \"escape\": -0.0025405826231011995, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -2.5362, \"times_seen\": 3.0}, {\"site\": 1164, \"mutant\": \"-\", \"escape\": -0.005682751165282377, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1164, \"mutant\": \"A\", \"escape\": -0.2868156435637605, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.085, \"times_seen\": 62.0}, {\"site\": 1164, \"mutant\": \"C\", \"escape\": -0.006362261448705726, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -1.4702, \"times_seen\": 22.0}, {\"site\": 1164, \"mutant\": \"D\", \"escape\": -0.6241381531342467, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0149, \"times_seen\": 94.0}, {\"site\": 1164, \"mutant\": \"E\", \"escape\": 0.03712256459563543, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.1787, \"times_seen\": 50.0}, {\"site\": 1164, \"mutant\": \"F\", \"escape\": -0.0010547680829222168, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.1835, \"times_seen\": 36.0}, {\"site\": 1164, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1164, \"mutant\": \"H\", \"escape\": 0.019685167511091475, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0658, \"times_seen\": 25.0}, {\"site\": 1164, \"mutant\": \"I\", \"escape\": 0.012498331728984392, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.0695, \"times_seen\": 17.0}, {\"site\": 1164, \"mutant\": \"K\", \"escape\": -0.8202168082462361, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.1964, \"times_seen\": 29.0}, {\"site\": 1164, \"mutant\": \"L\", \"escape\": -0.08229178826045393, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.2658, \"times_seen\": 61.0}, {\"site\": 1164, \"mutant\": \"M\", \"escape\": -0.0008388224285730986, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 1164, \"mutant\": \"N\", \"escape\": -0.010857149051852049, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0698, \"times_seen\": 25.0}, {\"site\": 1164, \"mutant\": \"P\", \"escape\": 0.009485361797706773, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0568, \"times_seen\": 47.0}, {\"site\": 1164, \"mutant\": \"Q\", \"escape\": -0.009270053719699335, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.1486, \"times_seen\": 23.0}, {\"site\": 1164, \"mutant\": \"R\", \"escape\": 0.21956244171553538, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0881, \"times_seen\": 144.0}, {\"site\": 1164, \"mutant\": \"S\", \"escape\": -0.11372635821155094, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.0842, \"times_seen\": 74.0}, {\"site\": 1164, \"mutant\": \"T\", \"escape\": -0.128138079325106, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": 0.066, \"times_seen\": 42.0}, {\"site\": 1164, \"mutant\": \"V\", \"escape\": -0.03781355304025132, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.1033, \"times_seen\": 91.0}, {\"site\": 1164, \"mutant\": \"W\", \"escape\": -0.11487881678807345, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.3422, \"times_seen\": 31.0}, {\"site\": 1164, \"mutant\": \"Y\", \"escape\": 0.794596690702875, \"epitope\": \"epitope 1\", \"reference_site\": \"1167\", \"functional effect\": -0.2037, \"times_seen\": 27.0}, {\"site\": 1165, \"mutant\": \"-\", \"escape\": -0.01396510844184136, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1165, \"mutant\": \"A\", \"escape\": -0.09457599113833166, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0497, \"times_seen\": 61.0}, {\"site\": 1165, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1165, \"mutant\": \"E\", \"escape\": -0.08001594437882176, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.1599, \"times_seen\": 32.0}, {\"site\": 1165, \"mutant\": \"G\", \"escape\": -0.1481457582315756, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": -0.0215, \"times_seen\": 81.0}, {\"site\": 1165, \"mutant\": \"H\", \"escape\": -0.12272184005910733, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0698, \"times_seen\": 112.0}, {\"site\": 1165, \"mutant\": \"N\", \"escape\": -0.22921074263769056, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.1006, \"times_seen\": 106.0}, {\"site\": 1165, \"mutant\": \"V\", \"escape\": -1.9455678288077192, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0377, \"times_seen\": 34.0}, {\"site\": 1165, \"mutant\": \"Y\", \"escape\": -0.16606812698726653, \"epitope\": \"epitope 1\", \"reference_site\": \"1168\", \"functional effect\": 0.0392, \"times_seen\": 92.0}, {\"site\": 1166, \"mutant\": \"-\", \"escape\": -0.005062368967134332, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1166, \"mutant\": \"F\", \"escape\": 0.2541834801683929, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.195, \"times_seen\": 80.0}, {\"site\": 1166, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1166, \"mutant\": \"L\", \"escape\": -0.020190419939048278, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.0663, \"times_seen\": 10.0}, {\"site\": 1166, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -3.1213, \"times_seen\": null}, {\"site\": 1166, \"mutant\": \"N\", \"escape\": -0.005166917533769102, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1166, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": -0.2359, \"times_seen\": null}, {\"site\": 1166, \"mutant\": \"T\", \"escape\": -0.12924782949756905, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.3117, \"times_seen\": 42.0}, {\"site\": 1166, \"mutant\": \"V\", \"escape\": -0.0935580507135335, \"epitope\": \"epitope 1\", \"reference_site\": \"1169\", \"functional effect\": 0.2283, \"times_seen\": 35.0}, {\"site\": 1167, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.391, \"times_seen\": null}, {\"site\": 1167, \"mutant\": \"A\", \"escape\": 0.02046905926934382, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.1606, \"times_seen\": 23.0}, {\"site\": 1167, \"mutant\": \"C\", \"escape\": 0.00357618526044875, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.7865, \"times_seen\": 2.0}, {\"site\": 1167, \"mutant\": \"F\", \"escape\": 0.35235783076169547, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.0314, \"times_seen\": 85.0}, {\"site\": 1167, \"mutant\": \"P\", \"escape\": -0.0781531268149723, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": 0.1262, \"times_seen\": 29.0}, {\"site\": 1167, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1167, \"mutant\": \"T\", \"escape\": 1.379707690492181, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.2179, \"times_seen\": 2.0}, {\"site\": 1167, \"mutant\": \"Y\", \"escape\": 0.15716857210080826, \"epitope\": \"epitope 1\", \"reference_site\": \"1170\", \"functional effect\": -0.0629, \"times_seen\": 59.0}, {\"site\": 1168, \"mutant\": \"-\", \"escape\": -0.0024560395413939272, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1168, \"mutant\": \"A\", \"escape\": 0.672699366859921, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0214, \"times_seen\": 21.0}, {\"site\": 1168, \"mutant\": \"C\", \"escape\": 0.011836944642120812, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -0.7442, \"times_seen\": 3.0}, {\"site\": 1168, \"mutant\": \"D\", \"escape\": -0.02008544200139729, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0388, \"times_seen\": 148.0}, {\"site\": 1168, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1168, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.1459, \"times_seen\": null}, {\"site\": 1168, \"mutant\": \"M\", \"escape\": -0.001726533202215466, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.1299, \"times_seen\": 1.0}, {\"site\": 1168, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -1.695, \"times_seen\": null}, {\"site\": 1168, \"mutant\": \"R\", \"escape\": -0.07479724302812558, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": -0.3251, \"times_seen\": 11.0}, {\"site\": 1168, \"mutant\": \"S\", \"escape\": -0.09641998895508948, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0186, \"times_seen\": 76.0}, {\"site\": 1168, \"mutant\": \"V\", \"escape\": -0.0915819808868911, \"epitope\": \"epitope 1\", \"reference_site\": \"1171\", \"functional effect\": 0.0614, \"times_seen\": 67.0}, {\"site\": 1169, \"mutant\": \"-\", \"escape\": -0.0056886816708036775, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1169, \"mutant\": \"F\", \"escape\": -0.008435805306251865, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.2852, \"times_seen\": 21.0}, {\"site\": 1169, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1169, \"mutant\": \"L\", \"escape\": -0.017621283704448695, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.0948, \"times_seen\": 8.0}, {\"site\": 1169, \"mutant\": \"M\", \"escape\": -0.0390888871234933, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.1903, \"times_seen\": 17.0}, {\"site\": 1169, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1169, \"mutant\": \"T\", \"escape\": -0.07037829991815839, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.392, \"times_seen\": 24.0}, {\"site\": 1169, \"mutant\": \"V\", \"escape\": -0.250999713565801, \"epitope\": \"epitope 1\", \"reference_site\": \"1172\", \"functional effect\": -0.0292, \"times_seen\": 27.0}, {\"site\": 1170, \"mutant\": \"-\", \"escape\": -0.0008230933778639614, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1170, \"mutant\": \"D\", \"escape\": 0.04223453496473411, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": 0.186, \"times_seen\": 22.0}, {\"site\": 1170, \"mutant\": \"H\", \"escape\": 0.007901657199745412, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.059, \"times_seen\": 5.0}, {\"site\": 1170, \"mutant\": \"I\", \"escape\": 0.012082477418456984, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.6553, \"times_seen\": 21.0}, {\"site\": 1170, \"mutant\": \"K\", \"escape\": 1.2137181350164927, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.4981, \"times_seen\": 21.0}, {\"site\": 1170, \"mutant\": \"M\", \"escape\": -0.04107840876998672, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.3446, \"times_seen\": 35.0}, {\"site\": 1170, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1170, \"mutant\": \"S\", \"escape\": 0.013148146185123803, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.1164, \"times_seen\": 45.0}, {\"site\": 1170, \"mutant\": \"T\", \"escape\": -0.04512664689760323, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.0951, \"times_seen\": 20.0}, {\"site\": 1170, \"mutant\": \"Y\", \"escape\": -0.0006242840270601756, \"epitope\": \"epitope 1\", \"reference_site\": \"1173\", \"functional effect\": -0.4194, \"times_seen\": 1.0}, {\"site\": 1171, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1171, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1171, \"mutant\": \"D\", \"escape\": -0.012973448274214202, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0621, \"times_seen\": 4.0}, {\"site\": 1171, \"mutant\": \"L\", \"escape\": 0.006503237941964628, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0907, \"times_seen\": 10.0}, {\"site\": 1171, \"mutant\": \"S\", \"escape\": -0.5070975662369999, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.2213, \"times_seen\": 59.0}, {\"site\": 1171, \"mutant\": \"T\", \"escape\": -0.15930044636291985, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.2596, \"times_seen\": 37.0}, {\"site\": 1171, \"mutant\": \"V\", \"escape\": 0.38541289509461324, \"epitope\": \"epitope 1\", \"reference_site\": \"1174\", \"functional effect\": 0.0478, \"times_seen\": 62.0}, {\"site\": 1172, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1172, \"mutant\": \"A\", \"escape\": 0.026396871880381943, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.4219, \"times_seen\": 19.0}, {\"site\": 1172, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -2.0152, \"times_seen\": null}, {\"site\": 1172, \"mutant\": \"F\", \"escape\": 0.000990390933177859, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -1.5856, \"times_seen\": 1.0}, {\"site\": 1172, \"mutant\": \"L\", \"escape\": -0.023592688694977347, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -1.0889, \"times_seen\": 27.0}, {\"site\": 1172, \"mutant\": \"P\", \"escape\": -0.017775538177876513, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.2426, \"times_seen\": 12.0}, {\"site\": 1172, \"mutant\": \"Q\", \"escape\": 0.90329969420826, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.1875, \"times_seen\": 22.0}, {\"site\": 1172, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1172, \"mutant\": \"T\", \"escape\": 0.03140609552198051, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.3201, \"times_seen\": 15.0}, {\"site\": 1172, \"mutant\": \"Y\", \"escape\": 0.031113230889180887, \"epitope\": \"epitope 1\", \"reference_site\": \"1175\", \"functional effect\": -0.4335, \"times_seen\": 5.0}, {\"site\": 1173, \"mutant\": \"*\", \"escape\": -0.010103386826588722, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -2.882, \"times_seen\": 6.0}, {\"site\": 1173, \"mutant\": \"A\", \"escape\": -0.039949935968844705, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2905, \"times_seen\": 66.0}, {\"site\": 1173, \"mutant\": \"C\", \"escape\": -0.4425305688999806, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.7802, \"times_seen\": 38.0}, {\"site\": 1173, \"mutant\": \"D\", \"escape\": -0.05413016721312051, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.9151, \"times_seen\": 28.0}, {\"site\": 1173, \"mutant\": \"E\", \"escape\": -0.01884334879637143, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -1.1258, \"times_seen\": 30.0}, {\"site\": 1173, \"mutant\": \"F\", \"escape\": 0.21514721650801988, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.4019, \"times_seen\": 42.0}, {\"site\": 1173, \"mutant\": \"G\", \"escape\": -0.05093570150739896, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.6579, \"times_seen\": 15.0}, {\"site\": 1173, \"mutant\": \"H\", \"escape\": -0.0406013964899503, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2005, \"times_seen\": 22.0}, {\"site\": 1173, \"mutant\": \"I\", \"escape\": 0.03522833304434524, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2854, \"times_seen\": 26.0}, {\"site\": 1173, \"mutant\": \"K\", \"escape\": -0.03701929315608048, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2019, \"times_seen\": 21.0}, {\"site\": 1173, \"mutant\": \"L\", \"escape\": -0.15319059332970086, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3821, \"times_seen\": 81.0}, {\"site\": 1173, \"mutant\": \"M\", \"escape\": 0.16389935275016226, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.03, \"times_seen\": 44.0}, {\"site\": 1173, \"mutant\": \"N\", \"escape\": -0.004864242119623722, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3721, \"times_seen\": 13.0}, {\"site\": 1173, \"mutant\": \"P\", \"escape\": -0.21818572095223765, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.5789, \"times_seen\": 39.0}, {\"site\": 1173, \"mutant\": \"Q\", \"escape\": -0.05683447766740472, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3196, \"times_seen\": 28.0}, {\"site\": 1173, \"mutant\": \"R\", \"escape\": -1.1644960984153352, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.2285, \"times_seen\": 104.0}, {\"site\": 1173, \"mutant\": \"S\", \"escape\": 0.06648303341315227, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.7665, \"times_seen\": 73.0}, {\"site\": 1173, \"mutant\": \"T\", \"escape\": -0.01766176083475781, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.7113, \"times_seen\": 30.0}, {\"site\": 1173, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1173, \"mutant\": \"W\", \"escape\": -0.006225260290629039, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": 0.0842, \"times_seen\": 25.0}, {\"site\": 1173, \"mutant\": \"Y\", \"escape\": -0.04318102330776112, \"epitope\": \"epitope 1\", \"reference_site\": \"1176\", \"functional effect\": -0.3186, \"times_seen\": 24.0}, {\"site\": 1174, \"mutant\": \"A\", \"escape\": -0.041008394821483087, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.1103, \"times_seen\": 22.0}, {\"site\": 1174, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.2962, \"times_seen\": null}, {\"site\": 1174, \"mutant\": \"G\", \"escape\": -0.00101586501559403, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1174, \"mutant\": \"I\", \"escape\": -0.04826599001373303, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": -0.1009, \"times_seen\": 20.0}, {\"site\": 1174, \"mutant\": \"L\", \"escape\": -0.8191470394942328, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.1073, \"times_seen\": 41.0}, {\"site\": 1174, \"mutant\": \"M\", \"escape\": 0.5606427039357547, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.0916, \"times_seen\": 26.0}, {\"site\": 1174, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1177\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1175, \"mutant\": \"D\", \"escape\": -0.002676641999797955, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": -0.1074, \"times_seen\": 34.0}, {\"site\": 1175, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1175, \"mutant\": \"H\", \"escape\": -0.009813050525512358, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.0489, \"times_seen\": 29.0}, {\"site\": 1175, \"mutant\": \"I\", \"escape\": 0.0017818919972236713, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.1337, \"times_seen\": 2.0}, {\"site\": 1175, \"mutant\": \"K\", \"escape\": 0.027521691729095746, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.008, \"times_seen\": 31.0}, {\"site\": 1175, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1175, \"mutant\": \"R\", \"escape\": -0.02460401560148101, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": -0.031, \"times_seen\": 8.0}, {\"site\": 1175, \"mutant\": \"S\", \"escape\": -0.03142877029601685, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.0274, \"times_seen\": 22.0}, {\"site\": 1175, \"mutant\": \"T\", \"escape\": -0.020094780157372944, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.191, \"times_seen\": 23.0}, {\"site\": 1175, \"mutant\": \"Y\", \"escape\": -0.007454456250819978, \"epitope\": \"epitope 1\", \"reference_site\": \"1178\", \"functional effect\": 0.1389, \"times_seen\": 35.0}, {\"site\": 1176, \"mutant\": \"F\", \"escape\": -0.00037976969084570325, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.3638, \"times_seen\": 21.0}, {\"site\": 1176, \"mutant\": \"H\", \"escape\": 0.007746650800873434, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.878, \"times_seen\": 8.0}, {\"site\": 1176, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1176, \"mutant\": \"L\", \"escape\": 0.014625870236140133, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.3533, \"times_seen\": 3.0}, {\"site\": 1176, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1176, \"mutant\": \"N\", \"escape\": -0.003337739808015683, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.3435, \"times_seen\": 1.0}, {\"site\": 1176, \"mutant\": \"T\", \"escape\": 0.0009214336030258714, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": -0.0605, \"times_seen\": 5.0}, {\"site\": 1176, \"mutant\": \"V\", \"escape\": -0.010390444647881622, \"epitope\": \"epitope 1\", \"reference_site\": \"1179\", \"functional effect\": 0.2336, \"times_seen\": 34.0}, {\"site\": 1177, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": -3.1214, \"times_seen\": null}, {\"site\": 1177, \"mutant\": \"E\", \"escape\": -0.025051344953096518, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.2389, \"times_seen\": 16.0}, {\"site\": 1177, \"mutant\": \"H\", \"escape\": -0.008341627336456449, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": -0.0602, \"times_seen\": 13.0}, {\"site\": 1177, \"mutant\": \"K\", \"escape\": 0.4407523155247829, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0837, \"times_seen\": 86.0}, {\"site\": 1177, \"mutant\": \"L\", \"escape\": -0.023648966021943597, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0438, \"times_seen\": 19.0}, {\"site\": 1177, \"mutant\": \"P\", \"escape\": 0.0077692093672888885, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": -1.8418, \"times_seen\": 6.0}, {\"site\": 1177, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1177, \"mutant\": \"R\", \"escape\": -0.012271426958226564, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.1147, \"times_seen\": 35.0}, {\"site\": 1177, \"mutant\": \"S\", \"escape\": 0.015365768673701008, \"epitope\": \"epitope 1\", \"reference_site\": \"1180\", \"functional effect\": 0.0368, \"times_seen\": 11.0}, {\"site\": 1178, \"mutant\": \"E\", \"escape\": -0.03692525969348357, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.328, \"times_seen\": 35.0}, {\"site\": 1178, \"mutant\": \"I\", \"escape\": -0.06252340121797183, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.022, \"times_seen\": 16.0}, {\"site\": 1178, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1178, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.1879, \"times_seen\": null}, {\"site\": 1178, \"mutant\": \"N\", \"escape\": -0.37356404955376277, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.1419, \"times_seen\": 65.0}, {\"site\": 1178, \"mutant\": \"Q\", \"escape\": 0.003412953496701589, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": 0.0397, \"times_seen\": 32.0}, {\"site\": 1178, \"mutant\": \"R\", \"escape\": 0.4297017016529867, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.0624, \"times_seen\": 63.0}, {\"site\": 1178, \"mutant\": \"T\", \"escape\": 0.013659067481392081, \"epitope\": \"epitope 1\", \"reference_site\": \"1181\", \"functional effect\": -0.0284, \"times_seen\": 23.0}, {\"site\": 1179, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -2.8676, \"times_seen\": null}, {\"site\": 1179, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1179, \"mutant\": \"D\", \"escape\": -0.003234912579118077, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.2404, \"times_seen\": 21.0}, {\"site\": 1179, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1179, \"mutant\": \"G\", \"escape\": -0.04787226055588556, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -0.1308, \"times_seen\": 14.0}, {\"site\": 1179, \"mutant\": \"I\", \"escape\": -0.007260718207624061, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -2.2387, \"times_seen\": 2.0}, {\"site\": 1179, \"mutant\": \"K\", \"escape\": -0.08934646554874914, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.0599, \"times_seen\": 64.0}, {\"site\": 1179, \"mutant\": \"Q\", \"escape\": -0.028543244442671978, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": 0.1102, \"times_seen\": 43.0}, {\"site\": 1179, \"mutant\": \"V\", \"escape\": 0.0021945906770646367, \"epitope\": \"epitope 1\", \"reference_site\": \"1182\", \"functional effect\": -2.2533, \"times_seen\": 1.0}, {\"site\": 1180, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1180, \"mutant\": \"F\", \"escape\": -0.003068319711396549, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -1.1997, \"times_seen\": 1.0}, {\"site\": 1180, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1180, \"mutant\": \"L\", \"escape\": 0.01171542592626744, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.0006, \"times_seen\": 9.0}, {\"site\": 1180, \"mutant\": \"M\", \"escape\": -0.048705758619342406, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.1599, \"times_seen\": 19.0}, {\"site\": 1180, \"mutant\": \"N\", \"escape\": -0.004312471854973251, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -3.0473, \"times_seen\": 1.0}, {\"site\": 1180, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -3.2623, \"times_seen\": null}, {\"site\": 1180, \"mutant\": \"T\", \"escape\": -0.0043188322712016565, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": -1.5486, \"times_seen\": 2.0}, {\"site\": 1180, \"mutant\": \"V\", \"escape\": -0.020729206007006253, \"epitope\": \"epitope 1\", \"reference_site\": \"1183\", \"functional effect\": 0.3074, \"times_seen\": 31.0}, {\"site\": 1181, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1181, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1181, \"mutant\": \"E\", \"escape\": -0.006718445120328252, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0134, \"times_seen\": 36.0}, {\"site\": 1181, \"mutant\": \"G\", \"escape\": -0.2575080758068505, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.2674, \"times_seen\": 96.0}, {\"site\": 1181, \"mutant\": \"H\", \"escape\": 0.0032244938578644337, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0345, \"times_seen\": 13.0}, {\"site\": 1181, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -2.8217, \"times_seen\": null}, {\"site\": 1181, \"mutant\": \"M\", \"escape\": 0.015768919405603352, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -0.0548, \"times_seen\": 17.0}, {\"site\": 1181, \"mutant\": \"N\", \"escape\": -0.07279012219182202, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.0246, \"times_seen\": 105.0}, {\"site\": 1181, \"mutant\": \"T\", \"escape\": -0.020225697703718643, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.029, \"times_seen\": 13.0}, {\"site\": 1181, \"mutant\": \"V\", \"escape\": -0.004921277752205023, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": -1.9232, \"times_seen\": 1.0}, {\"site\": 1181, \"mutant\": \"Y\", \"escape\": -0.18240530063539664, \"epitope\": \"epitope 1\", \"reference_site\": \"1184\", \"functional effect\": 0.073, \"times_seen\": 95.0}, {\"site\": 1182, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -3.1155, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"C\", \"escape\": -0.027369215976582338, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.1659, \"times_seen\": 59.0}, {\"site\": 1182, \"mutant\": \"G\", \"escape\": -0.15085673101615307, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -0.3745, \"times_seen\": 14.0}, {\"site\": 1182, \"mutant\": \"H\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"I\", \"escape\": -0.009989645998875307, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.091, \"times_seen\": 2.0}, {\"site\": 1182, \"mutant\": \"K\", \"escape\": -0.015038318592090805, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.157, \"times_seen\": 9.0}, {\"site\": 1182, \"mutant\": \"L\", \"escape\": -0.036812630226011125, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.0256, \"times_seen\": 41.0}, {\"site\": 1182, \"mutant\": \"N\", \"escape\": -0.05387664967870056, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.0854, \"times_seen\": 20.0}, {\"site\": 1182, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"S\", \"escape\": -0.05219075708863294, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -0.0833, \"times_seen\": 84.0}, {\"site\": 1182, \"mutant\": \"T\", \"escape\": -0.014514766413258742, \"epitope\": \"epitope 1\", \"reference_site\": \"1185\", \"functional effect\": -0.1672, \"times_seen\": 1.0}, {\"site\": 1183, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -1.4169, \"times_seen\": null}, {\"site\": 1183, \"mutant\": \"F\", \"escape\": -0.02857788682391275, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": 0.4069, \"times_seen\": 15.0}, {\"site\": 1183, \"mutant\": \"I\", \"escape\": -0.009736721278322471, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -0.178, \"times_seen\": 15.0}, {\"site\": 1183, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1183, \"mutant\": \"M\", \"escape\": -0.010751233587222284, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -0.0126, \"times_seen\": 4.0}, {\"site\": 1183, \"mutant\": \"P\", \"escape\": -0.000498733851843554, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -2.4142, \"times_seen\": 1.0}, {\"site\": 1183, \"mutant\": \"Q\", \"escape\": 0.00912603050209808, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -2.1079, \"times_seen\": 1.0}, {\"site\": 1183, \"mutant\": \"V\", \"escape\": -0.003137075148281254, \"epitope\": \"epitope 1\", \"reference_site\": \"1186\", \"functional effect\": -2.0339, \"times_seen\": 1.0}, {\"site\": 1184, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1184, \"mutant\": \"D\", \"escape\": -0.41733564283512536, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": 0.3598, \"times_seen\": 44.0}, {\"site\": 1184, \"mutant\": \"H\", \"escape\": 0.011308149662850082, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": 0.0092, \"times_seen\": 5.0}, {\"site\": 1184, \"mutant\": \"I\", \"escape\": 0.01339914907965933, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.3623, \"times_seen\": 23.0}, {\"site\": 1184, \"mutant\": \"K\", \"escape\": 0.0005843455366440954, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.2011, \"times_seen\": 36.0}, {\"site\": 1184, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1184, \"mutant\": \"S\", \"escape\": 0.05747439648293393, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.1086, \"times_seen\": 28.0}, {\"site\": 1184, \"mutant\": \"T\", \"escape\": -0.005746767428258364, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.02, \"times_seen\": 22.0}, {\"site\": 1184, \"mutant\": \"Y\", \"escape\": -0.03796633619690404, \"epitope\": \"epitope 1\", \"reference_site\": \"1187\", \"functional effect\": -0.1487, \"times_seen\": 36.0}, {\"site\": 1185, \"mutant\": \"*\", \"escape\": -0.5886727860069796, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -2.5368, \"times_seen\": 2.0}, {\"site\": 1185, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1185, \"mutant\": \"A\", \"escape\": -0.035060067604459295, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -0.0764, \"times_seen\": 45.0}, {\"site\": 1185, \"mutant\": \"D\", \"escape\": -0.37040921059923876, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.1741, \"times_seen\": 70.0}, {\"site\": 1185, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1185, \"mutant\": \"G\", \"escape\": 0.060800678875102813, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.0898, \"times_seen\": 45.0}, {\"site\": 1185, \"mutant\": \"K\", \"escape\": -0.041075610475295204, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.0326, \"times_seen\": 130.0}, {\"site\": 1185, \"mutant\": \"Q\", \"escape\": -0.09714749115502935, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -0.1775, \"times_seen\": 21.0}, {\"site\": 1185, \"mutant\": \"R\", \"escape\": -0.036933643084900665, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": -0.3296, \"times_seen\": 17.0}, {\"site\": 1185, \"mutant\": \"S\", \"escape\": 0.002729170835723077, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.2637, \"times_seen\": 12.0}, {\"site\": 1185, \"mutant\": \"V\", \"escape\": -0.0020086929015605275, \"epitope\": \"epitope 1\", \"reference_site\": \"1188\", \"functional effect\": 0.1173, \"times_seen\": 33.0}, {\"site\": 1186, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1186, \"mutant\": \"A\", \"escape\": -0.03484457713374005, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.2116, \"times_seen\": 18.0}, {\"site\": 1186, \"mutant\": \"F\", \"escape\": -0.11163244257106644, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.1328, \"times_seen\": 35.0}, {\"site\": 1186, \"mutant\": \"G\", \"escape\": -0.012232452848322401, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1186, \"mutant\": \"I\", \"escape\": -1.4258649165939783, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -0.1789, \"times_seen\": 38.0}, {\"site\": 1186, \"mutant\": \"L\", \"escape\": -0.012246247066943418, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -0.061, \"times_seen\": 1.0}, {\"site\": 1186, \"mutant\": \"M\", \"escape\": -0.021752063296599306, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -0.0626, \"times_seen\": 16.0}, {\"site\": 1186, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": -2.9313, \"times_seen\": null}, {\"site\": 1186, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1189\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"D\", \"escape\": -0.009849101008070658, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.0999, \"times_seen\": 3.0}, {\"site\": 1187, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.126, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -3.2974, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"S\", \"escape\": -0.051785778450465246, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": 0.2268, \"times_seen\": 49.0}, {\"site\": 1187, \"mutant\": \"T\", \"escape\": -0.03959768928832335, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.0464, \"times_seen\": 57.0}, {\"site\": 1187, \"mutant\": \"V\", \"escape\": 0.037409816218270345, \"epitope\": \"epitope 1\", \"reference_site\": \"1190\", \"functional effect\": -0.6084, \"times_seen\": 42.0}, {\"site\": 1188, \"mutant\": \"*\", \"escape\": 0.01293599589173396, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -2.9248, \"times_seen\": 4.0}, {\"site\": 1188, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1188, \"mutant\": \"A\", \"escape\": -0.04264168646986886, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0125, \"times_seen\": 72.0}, {\"site\": 1188, \"mutant\": \"C\", \"escape\": -0.008937322669296166, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0765, \"times_seen\": 35.0}, {\"site\": 1188, \"mutant\": \"D\", \"escape\": -1.7464982447611825, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.254, \"times_seen\": 38.0}, {\"site\": 1188, \"mutant\": \"E\", \"escape\": 0.006433960645017046, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.1586, \"times_seen\": 53.0}, {\"site\": 1188, \"mutant\": \"F\", \"escape\": 1.2517498064897783, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0813, \"times_seen\": 44.0}, {\"site\": 1188, \"mutant\": \"G\", \"escape\": -0.10654603969116891, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.3656, \"times_seen\": 101.0}, {\"site\": 1188, \"mutant\": \"H\", \"escape\": -0.033346950356334594, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0095, \"times_seen\": 23.0}, {\"site\": 1188, \"mutant\": \"I\", \"escape\": 0.00016565677487674274, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0895, \"times_seen\": 30.0}, {\"site\": 1188, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1188, \"mutant\": \"L\", \"escape\": 0.2911344506509196, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0082, \"times_seen\": 94.0}, {\"site\": 1188, \"mutant\": \"M\", \"escape\": -0.006067886513417669, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0308, \"times_seen\": 57.0}, {\"site\": 1188, \"mutant\": \"N\", \"escape\": -0.060427949486635164, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0363, \"times_seen\": 102.0}, {\"site\": 1188, \"mutant\": \"P\", \"escape\": 0.049040928323402705, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -2.8372, \"times_seen\": 6.0}, {\"site\": 1188, \"mutant\": \"Q\", \"escape\": 0.09631483892714802, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0239, \"times_seen\": 43.0}, {\"site\": 1188, \"mutant\": \"R\", \"escape\": 0.026110903684530225, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.077, \"times_seen\": 153.0}, {\"site\": 1188, \"mutant\": \"S\", \"escape\": -0.29039330378551254, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0966, \"times_seen\": 80.0}, {\"site\": 1188, \"mutant\": \"T\", \"escape\": -0.06660609580218484, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.1724, \"times_seen\": 74.0}, {\"site\": 1188, \"mutant\": \"V\", \"escape\": -0.4306830376569433, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": 0.0846, \"times_seen\": 94.0}, {\"site\": 1188, \"mutant\": \"W\", \"escape\": -0.06433117623807597, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0432, \"times_seen\": 39.0}, {\"site\": 1188, \"mutant\": \"Y\", \"escape\": 0.7913620600191171, \"epitope\": \"epitope 1\", \"reference_site\": \"1191\", \"functional effect\": -0.0513, \"times_seen\": 22.0}, {\"site\": 1189, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -1.1747, \"times_seen\": null}, {\"site\": 1189, \"mutant\": \"D\", \"escape\": -0.1752914433937117, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.0737, \"times_seen\": 84.0}, {\"site\": 1189, \"mutant\": \"H\", \"escape\": 0.9026051238568596, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.1333, \"times_seen\": 26.0}, {\"site\": 1189, \"mutant\": \"I\", \"escape\": -0.052461890992666495, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.2161, \"times_seen\": 28.0}, {\"site\": 1189, \"mutant\": \"K\", \"escape\": -0.5948408542396564, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.2615, \"times_seen\": 42.0}, {\"site\": 1189, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1189, \"mutant\": \"S\", \"escape\": 0.3866451628651819, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.1757, \"times_seen\": 71.0}, {\"site\": 1189, \"mutant\": \"T\", \"escape\": -0.23805327401787638, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.0432, \"times_seen\": 71.0}, {\"site\": 1189, \"mutant\": \"Y\", \"escape\": -0.05438366104913499, \"epitope\": \"epitope 1\", \"reference_site\": \"1192\", \"functional effect\": -0.1824, \"times_seen\": 31.0}, {\"site\": 1190, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"M\", \"escape\": 0.00783876416536153, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": 0.1436, \"times_seen\": 11.0}, {\"site\": 1190, \"mutant\": \"P\", \"escape\": -0.0010096269982026987, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -3.0572, \"times_seen\": 7.0}, {\"site\": 1190, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -2.8743, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -3.1097, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1193\", \"functional effect\": -1.4736, \"times_seen\": null}, {\"site\": 1191, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1191, \"mutant\": \"D\", \"escape\": -0.0031857871091909664, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.2563, \"times_seen\": 2.0}, {\"site\": 1191, \"mutant\": \"H\", \"escape\": -0.018127010454356794, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.0998, \"times_seen\": 11.0}, {\"site\": 1191, \"mutant\": \"K\", \"escape\": -0.04478324985104665, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.1808, \"times_seen\": 25.0}, {\"site\": 1191, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1191, \"mutant\": \"S\", \"escape\": -0.01537663977893041, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -0.4681, \"times_seen\": 14.0}, {\"site\": 1191, \"mutant\": \"T\", \"escape\": -0.0027257467490214874, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -0.7439, \"times_seen\": 1.0}, {\"site\": 1191, \"mutant\": \"Y\", \"escape\": 0.011454888921231995, \"epitope\": \"epitope 1\", \"reference_site\": \"1194\", \"functional effect\": -1.0239, \"times_seen\": 10.0}, {\"site\": 1192, \"mutant\": \"*\", \"escape\": -0.005585580703368409, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -2.6467, \"times_seen\": 2.0}, {\"site\": 1192, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1192, \"mutant\": \"A\", \"escape\": -0.018376153072004082, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.1746, \"times_seen\": 8.0}, {\"site\": 1192, \"mutant\": \"D\", \"escape\": -0.13299847571519277, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.0335, \"times_seen\": 49.0}, {\"site\": 1192, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1192, \"mutant\": \"G\", \"escape\": -0.3049278848037211, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": 0.0492, \"times_seen\": 62.0}, {\"site\": 1192, \"mutant\": \"K\", \"escape\": -0.04783960837389113, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.2683, \"times_seen\": 79.0}, {\"site\": 1192, \"mutant\": \"Q\", \"escape\": 0.055746472678626466, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.1986, \"times_seen\": 25.0}, {\"site\": 1192, \"mutant\": \"S\", \"escape\": -0.02817578491597827, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": -0.1909, \"times_seen\": 9.0}, {\"site\": 1192, \"mutant\": \"V\", \"escape\": 0.004608813614781396, \"epitope\": \"epitope 1\", \"reference_site\": \"1195\", \"functional effect\": 0.0115, \"times_seen\": 14.0}, {\"site\": 1193, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -2.8134, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -0.9579, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"F\", \"escape\": -2.662926242429071, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -1.122, \"times_seen\": 36.0}, {\"site\": 1193, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -3.2983, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"T\", \"escape\": -1.9670263267989618, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -0.0384, \"times_seen\": 29.0}, {\"site\": 1193, \"mutant\": \"Y\", \"escape\": -0.2647590375282588, \"epitope\": \"epitope 1\", \"reference_site\": \"1196\", \"functional effect\": -1.4316, \"times_seen\": 26.0}, {\"site\": 1194, \"mutant\": \"-\", \"escape\": 0.01907753025026367, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1194, \"mutant\": \"F\", \"escape\": -0.13293838664265456, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.2202, \"times_seen\": 30.0}, {\"site\": 1194, \"mutant\": \"I\", \"escape\": -0.005203357860640578, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.066, \"times_seen\": 12.0}, {\"site\": 1194, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1194, \"mutant\": \"M\", \"escape\": -0.08887468718932923, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": 0.0823, \"times_seen\": 35.0}, {\"site\": 1194, \"mutant\": \"P\", \"escape\": 0.1603001825048892, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -2.5545, \"times_seen\": 25.0}, {\"site\": 1194, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.7933, \"times_seen\": null}, {\"site\": 1194, \"mutant\": \"R\", \"escape\": -0.006879445369149491, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -1.8685, \"times_seen\": 2.0}, {\"site\": 1194, \"mutant\": \"S\", \"escape\": 0.02150517891066818, \"epitope\": \"epitope 1\", \"reference_site\": \"1197\", \"functional effect\": -0.832, \"times_seen\": 8.0}, {\"site\": 1195, \"mutant\": \"-\", \"escape\": 0.01840980914273227, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1195, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -2.2422, \"times_seen\": null}, {\"site\": 1195, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1195, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -2.8804, \"times_seen\": null}, {\"site\": 1195, \"mutant\": \"N\", \"escape\": 0.0012588911994227561, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.4286, \"times_seen\": 4.0}, {\"site\": 1195, \"mutant\": \"S\", \"escape\": -0.03558776126083233, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.5658, \"times_seen\": 8.0}, {\"site\": 1195, \"mutant\": \"T\", \"escape\": -0.03058424309865171, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": -0.3756, \"times_seen\": 17.0}, {\"site\": 1195, \"mutant\": \"V\", \"escape\": -0.015108769777870488, \"epitope\": \"epitope 1\", \"reference_site\": \"1198\", \"functional effect\": 0.0335, \"times_seen\": 32.0}, {\"site\": 1196, \"mutant\": \"-\", \"escape\": 0.018073071922923654, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1196, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1196, \"mutant\": \"E\", \"escape\": -0.02613445110316243, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.3481, \"times_seen\": 24.0}, {\"site\": 1196, \"mutant\": \"G\", \"escape\": 0.06422357335686173, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.5742, \"times_seen\": 98.0}, {\"site\": 1196, \"mutant\": \"H\", \"escape\": -0.042814291682302295, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.7052, \"times_seen\": 45.0}, {\"site\": 1196, \"mutant\": \"N\", \"escape\": -0.007955162296135776, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.3864, \"times_seen\": 124.0}, {\"site\": 1196, \"mutant\": \"S\", \"escape\": -0.4064691441858077, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.4627, \"times_seen\": 21.0}, {\"site\": 1196, \"mutant\": \"V\", \"escape\": 0.05940019987716312, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.6228, \"times_seen\": 14.0}, {\"site\": 1196, \"mutant\": \"Y\", \"escape\": -0.005292096716023853, \"epitope\": \"epitope 1\", \"reference_site\": \"1199\", \"functional effect\": -0.6752, \"times_seen\": 80.0}, {\"site\": 1197, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1197, \"mutant\": \"F\", \"escape\": -0.6127982984903455, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.6132, \"times_seen\": 115.0}, {\"site\": 1197, \"mutant\": \"H\", \"escape\": 0.0006429750582628715, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -1.243, \"times_seen\": 2.0}, {\"site\": 1197, \"mutant\": \"I\", \"escape\": 0.045009551961510526, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.2187, \"times_seen\": 119.0}, {\"site\": 1197, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1197, \"mutant\": \"P\", \"escape\": -0.03820698292558233, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -1.2615, \"times_seen\": 17.0}, {\"site\": 1197, \"mutant\": \"R\", \"escape\": -0.005046342485264242, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.891, \"times_seen\": 2.0}, {\"site\": 1197, \"mutant\": \"V\", \"escape\": -0.02437135285483134, \"epitope\": \"epitope 1\", \"reference_site\": \"1200\", \"functional effect\": -0.4283, \"times_seen\": 17.0}, {\"site\": 1198, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -2.949, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"E\", \"escape\": 0.039600768113923365, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": 0.1791, \"times_seen\": 14.0}, {\"site\": 1198, \"mutant\": \"H\", \"escape\": 0.12615902126710554, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.1289, \"times_seen\": 77.0}, {\"site\": 1198, \"mutant\": \"K\", \"escape\": 0.07421539008689902, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.0713, \"times_seen\": 48.0}, {\"site\": 1198, \"mutant\": \"L\", \"escape\": -0.057774852025759015, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.2985, \"times_seen\": 86.0}, {\"site\": 1198, \"mutant\": \"N\", \"escape\": -0.027819027285849597, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.1313, \"times_seen\": 14.0}, {\"site\": 1198, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"R\", \"escape\": -0.10471146945447268, \"epitope\": \"epitope 1\", \"reference_site\": \"1201\", \"functional effect\": -0.0902, \"times_seen\": 72.0}, {\"site\": 1199, \"mutant\": \"*\", \"escape\": -5.722878393507979e-05, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -3.0098, \"times_seen\": 1.0}, {\"site\": 1199, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1199, \"mutant\": \"A\", \"escape\": 0.027934493582073797, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.2665, \"times_seen\": 11.0}, {\"site\": 1199, \"mutant\": \"D\", \"escape\": -0.13273572732133354, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.1355, \"times_seen\": 30.0}, {\"site\": 1199, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1199, \"mutant\": \"G\", \"escape\": -0.04379871144913463, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.5713, \"times_seen\": 54.0}, {\"site\": 1199, \"mutant\": \"K\", \"escape\": 0.4052599912347347, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.5992, \"times_seen\": 119.0}, {\"site\": 1199, \"mutant\": \"Q\", \"escape\": 0.3447633893872057, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.2673, \"times_seen\": 22.0}, {\"site\": 1199, \"mutant\": \"S\", \"escape\": -0.056572458851757226, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.4779, \"times_seen\": 7.0}, {\"site\": 1199, \"mutant\": \"V\", \"escape\": 0.03984885335523366, \"epitope\": \"epitope 1\", \"reference_site\": \"1202\", \"functional effect\": -0.4334, \"times_seen\": 13.0}, {\"site\": 1200, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1200, \"mutant\": \"F\", \"escape\": -0.11906223004217742, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -0.5025, \"times_seen\": 48.0}, {\"site\": 1200, \"mutant\": \"H\", \"escape\": -0.0184041181189824, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -2.377, \"times_seen\": 5.0}, {\"site\": 1200, \"mutant\": \"I\", \"escape\": 0.01395376796528013, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -0.37, \"times_seen\": 12.0}, {\"site\": 1200, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1200, \"mutant\": \"M\", \"escape\": -0.05624892684092937, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -0.075, \"times_seen\": 28.0}, {\"site\": 1200, \"mutant\": \"P\", \"escape\": 0.005671612928468432, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.7428, \"times_seen\": 12.0}, {\"site\": 1200, \"mutant\": \"Q\", \"escape\": 0.16017727043591629, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.8301, \"times_seen\": 8.0}, {\"site\": 1200, \"mutant\": \"R\", \"escape\": -0.0029351418015125604, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.7863, \"times_seen\": 2.0}, {\"site\": 1200, \"mutant\": \"V\", \"escape\": -0.0032407881899194097, \"epitope\": \"epitope 1\", \"reference_site\": \"1203\", \"functional effect\": -1.007, \"times_seen\": 1.0}, {\"site\": 1201, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1201, \"mutant\": \"A\", \"escape\": -0.011372537374739275, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.4525, \"times_seen\": 2.0}, {\"site\": 1201, \"mutant\": \"C\", \"escape\": -0.013112554864871657, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -1.2555, \"times_seen\": 4.0}, {\"site\": 1201, \"mutant\": \"D\", \"escape\": 0.07248300453204741, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.3785, \"times_seen\": 34.0}, {\"site\": 1201, \"mutant\": \"E\", \"escape\": -0.012785690490623457, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.9138, \"times_seen\": 2.0}, {\"site\": 1201, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1201, \"mutant\": \"R\", \"escape\": -0.021015583038813356, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.8861, \"times_seen\": 8.0}, {\"site\": 1201, \"mutant\": \"S\", \"escape\": -0.05491465709131314, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -0.3427, \"times_seen\": 31.0}, {\"site\": 1201, \"mutant\": \"V\", \"escape\": -1.471271766184725, \"epitope\": \"epitope 1\", \"reference_site\": \"1204\", \"functional effect\": -1.2251, \"times_seen\": 12.0}, {\"site\": 1202, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1202, \"mutant\": \"E\", \"escape\": 0.09394361017684175, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.1113, \"times_seen\": 12.0}, {\"site\": 1202, \"mutant\": \"I\", \"escape\": -0.006695554801913763, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1202, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1202, \"mutant\": \"N\", \"escape\": 0.004571857879127062, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.1242, \"times_seen\": 56.0}, {\"site\": 1202, \"mutant\": \"Q\", \"escape\": 0.0010802588827340059, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": -0.0272, \"times_seen\": 17.0}, {\"site\": 1202, \"mutant\": \"R\", \"escape\": 0.04985171013048969, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 1202, \"mutant\": \"T\", \"escape\": 0.13824500521841004, \"epitope\": \"epitope 1\", \"reference_site\": \"1205\", \"functional effect\": 0.1046, \"times_seen\": 22.0}, {\"site\": 1203, \"mutant\": \"-\", \"escape\": -0.0017711753756559235, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1203, \"mutant\": \"C\", \"escape\": 0.005348817600873728, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -1.5381, \"times_seen\": 7.0}, {\"site\": 1203, \"mutant\": \"F\", \"escape\": -0.027326051877656906, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -0.1585, \"times_seen\": 21.0}, {\"site\": 1203, \"mutant\": \"H\", \"escape\": -0.00592528088200901, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -0.9419, \"times_seen\": 13.0}, {\"site\": 1203, \"mutant\": \"N\", \"escape\": -0.006672006967267968, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -1.0559, \"times_seen\": 2.0}, {\"site\": 1203, \"mutant\": \"S\", \"escape\": -0.0016796450040790416, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": -0.5054, \"times_seen\": 1.0}, {\"site\": 1203, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1206\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1204, \"mutant\": \"*\", \"escape\": -0.0038717201171385297, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.7288, \"times_seen\": 1.0}, {\"site\": 1204, \"mutant\": \"-\", \"escape\": -0.0030533483662698838, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1204, \"mutant\": \"A\", \"escape\": -0.0048289083397068154, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.9284, \"times_seen\": 8.0}, {\"site\": 1204, \"mutant\": \"D\", \"escape\": -0.3330434565020902, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.2349, \"times_seen\": 79.0}, {\"site\": 1204, \"mutant\": \"E\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1204, \"mutant\": \"G\", \"escape\": 0.0017874227843884861, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.075, \"times_seen\": 14.0}, {\"site\": 1204, \"mutant\": \"K\", \"escape\": -0.014183797745808949, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -1.1686, \"times_seen\": 91.0}, {\"site\": 1204, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.2522, \"times_seen\": null}, {\"site\": 1204, \"mutant\": \"V\", \"escape\": -0.012681660883942443, \"epitope\": \"epitope 1\", \"reference_site\": \"1207\", \"functional effect\": -0.544, \"times_seen\": 20.0}, {\"site\": 1205, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -2.8389, \"times_seen\": null}, {\"site\": 1205, \"mutant\": \"-\", \"escape\": -0.00399856481071715, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1205, \"mutant\": \"E\", \"escape\": -0.012152034001854377, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": 0.2082, \"times_seen\": 101.0}, {\"site\": 1205, \"mutant\": \"H\", \"escape\": -0.18584787970023528, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -0.5391, \"times_seen\": 131.0}, {\"site\": 1205, \"mutant\": \"K\", \"escape\": -0.03440718822344448, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -1.0514, \"times_seen\": 61.0}, {\"site\": 1205, \"mutant\": \"L\", \"escape\": -0.049878796090876504, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -0.3741, \"times_seen\": 25.0}, {\"site\": 1205, \"mutant\": \"M\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -0.8033, \"times_seen\": null}, {\"site\": 1205, \"mutant\": \"Q\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1205, \"mutant\": \"R\", \"escape\": -0.18591398541501575, \"epitope\": \"epitope 1\", \"reference_site\": \"1208\", \"functional effect\": -1.2458, \"times_seen\": 30.0}, {\"site\": 1206, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -2.9748, \"times_seen\": null}, {\"site\": 1206, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1206, \"mutant\": \"C\", \"escape\": -0.009941771423148869, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.5884, \"times_seen\": 5.0}, {\"site\": 1206, \"mutant\": \"D\", \"escape\": -0.005285152077548695, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -0.9888, \"times_seen\": 1.0}, {\"site\": 1206, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -0.5447, \"times_seen\": null}, {\"site\": 1206, \"mutant\": \"H\", \"escape\": -0.08526791976958788, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.1283, \"times_seen\": 22.0}, {\"site\": 1206, \"mutant\": \"I\", \"escape\": -0.0014743172337979206, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -0.3489, \"times_seen\": 1.0}, {\"site\": 1206, \"mutant\": \"N\", \"escape\": -0.00423788466313125, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": -1.2513, \"times_seen\": 1.0}, {\"site\": 1206, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1209\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -2.6414, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"L\", \"escape\": 0.007930315875674677, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.2619, \"times_seen\": 14.0}, {\"site\": 1207, \"mutant\": \"M\", \"escape\": 0.836984576728789, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.1508, \"times_seen\": 17.0}, {\"site\": 1207, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -1.3902, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"T\", \"escape\": 0.031528778306385424, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.6196, \"times_seen\": 43.0}, {\"site\": 1207, \"mutant\": \"V\", \"escape\": -0.44648798592669703, \"epitope\": \"epitope 1\", \"reference_site\": \"1210\", \"functional effect\": -0.0089, \"times_seen\": 38.0}, {\"site\": 1208, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -2.8901, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"E\", \"escape\": -0.019517253363960863, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -2.2165, \"times_seen\": 6.0}, {\"site\": 1208, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": 1.3076, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"M\", \"escape\": 0.0015399252707286955, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.5475, \"times_seen\": 2.0}, {\"site\": 1208, \"mutant\": \"N\", \"escape\": 0.06660312022326514, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.6971, \"times_seen\": 21.0}, {\"site\": 1208, \"mutant\": \"R\", \"escape\": 0.00697573010472573, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.1191, \"times_seen\": 5.0}, {\"site\": 1208, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1211\", \"functional effect\": -0.9017, \"times_seen\": null}, {\"site\": 1209, \"mutant\": \"*\", \"escape\": 0.030010113884898913, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.4534, \"times_seen\": 5.0}, {\"site\": 1209, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1209, \"mutant\": \"C\", \"escape\": -0.032933302967889495, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.3843, \"times_seen\": 14.0}, {\"site\": 1209, \"mutant\": \"G\", \"escape\": -0.0019204350050118714, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.2355, \"times_seen\": 1.0}, {\"site\": 1209, \"mutant\": \"L\", \"escape\": 0.015167045145337812, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.2128, \"times_seen\": 14.0}, {\"site\": 1209, \"mutant\": \"R\", \"escape\": -0.00466492385483428, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": -2.4587, \"times_seen\": 2.0}, {\"site\": 1209, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1212\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -0.9333, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"L\", \"escape\": -0.006558747023427252, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -2.2115, \"times_seen\": 3.0}, {\"site\": 1210, \"mutant\": \"P\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"Q\", \"escape\": -0.03531283173054466, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.333, \"times_seen\": 6.0}, {\"site\": 1210, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.1673, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"S\", \"escape\": -0.0660109812599817, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.0767, \"times_seen\": 37.0}, {\"site\": 1210, \"mutant\": \"T\", \"escape\": -0.004995193204389684, \"epitope\": \"epitope 1\", \"reference_site\": \"1213\", \"functional effect\": -1.9568, \"times_seen\": 4.0}, {\"site\": 1211, \"mutant\": \"*\", \"escape\": -0.014865202230703973, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -2.4638, \"times_seen\": 8.0}, {\"site\": 1211, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1211, \"mutant\": \"C\", \"escape\": -0.024934901630337222, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -2.5278, \"times_seen\": 19.0}, {\"site\": 1211, \"mutant\": \"F\", \"escape\": 0.018955256643766724, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -0.6012, \"times_seen\": 19.0}, {\"site\": 1211, \"mutant\": \"G\", \"escape\": 0.03507452939757441, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -1.6721, \"times_seen\": 11.0}, {\"site\": 1211, \"mutant\": \"L\", \"escape\": 0.05148073299606239, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -1.6378, \"times_seen\": 23.0}, {\"site\": 1211, \"mutant\": \"R\", \"escape\": -0.015146484313747125, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 1211, \"mutant\": \"S\", \"escape\": -0.004449255501352578, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": -1.5455, \"times_seen\": 1.0}, {\"site\": 1211, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1214\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1212, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -3.1551, \"times_seen\": null}, {\"site\": 1212, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1212, \"mutant\": \"C\", \"escape\": -0.023488724327438065, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -2.2095, \"times_seen\": 6.0}, {\"site\": 1212, \"mutant\": \"F\", \"escape\": 0.060736395388904595, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -0.3552, \"times_seen\": 50.0}, {\"site\": 1212, \"mutant\": \"H\", \"escape\": 0.1812063769356662, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -1.0761, \"times_seen\": 111.0}, {\"site\": 1212, \"mutant\": \"N\", \"escape\": -0.25223782752682766, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": -0.9324, \"times_seen\": 37.0}, {\"site\": 1212, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1215\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"F\", \"escape\": 0.4478782059198987, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -1.6606, \"times_seen\": 39.0}, {\"site\": 1213, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"L\", \"escape\": 0.007839629504705412, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.6364, \"times_seen\": 35.0}, {\"site\": 1213, \"mutant\": \"M\", \"escape\": -0.07404127995329446, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.7324, \"times_seen\": 45.0}, {\"site\": 1213, \"mutant\": \"N\", \"escape\": -0.0018516392417141495, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.375, \"times_seen\": 1.0}, {\"site\": 1213, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.4976, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"S\", \"escape\": 0.5322543324173851, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.4035, \"times_seen\": 72.0}, {\"site\": 1213, \"mutant\": \"T\", \"escape\": -0.5292169017496843, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.1313, \"times_seen\": 114.0}, {\"site\": 1213, \"mutant\": \"V\", \"escape\": 0.03581260927649989, \"epitope\": \"epitope 1\", \"reference_site\": \"1216\", \"functional effect\": -0.0003, \"times_seen\": 69.0}, {\"site\": 1214, \"mutant\": \"*\", \"escape\": 0.004445225369854286, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -2.8152, \"times_seen\": 8.0}, {\"site\": 1214, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1214, \"mutant\": \"C\", \"escape\": -0.01232962154176481, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -1.7056, \"times_seen\": 3.0}, {\"site\": 1214, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -1.5744, \"times_seen\": null}, {\"site\": 1214, \"mutant\": \"L\", \"escape\": -0.0032905970132704196, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -1.4455, \"times_seen\": 59.0}, {\"site\": 1214, \"mutant\": \"R\", \"escape\": 0.01803049701589535, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -2.4405, \"times_seen\": 1.0}, {\"site\": 1214, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 1214, \"mutant\": \"W\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1217\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"I\", \"escape\": -0.08472310924015357, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.4166, \"times_seen\": 12.0}, {\"site\": 1215, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"M\", \"escape\": 0.026660364231968155, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.5232, \"times_seen\": 6.0}, {\"site\": 1215, \"mutant\": \"P\", \"escape\": 0.012679473330596373, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -1.3295, \"times_seen\": 12.0}, {\"site\": 1215, \"mutant\": \"Q\", \"escape\": -0.0036898804798606052, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -1.5515, \"times_seen\": 1.0}, {\"site\": 1215, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -2.8079, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"V\", \"escape\": -0.0037283225586789634, \"epitope\": \"epitope 1\", \"reference_site\": \"1218\", \"functional effect\": -0.9749, \"times_seen\": 1.0}, {\"site\": 1216, \"mutant\": \"*\", \"escape\": 0.007896115383941265, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -2.5133, \"times_seen\": 9.0}, {\"site\": 1216, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1216, \"mutant\": \"A\", \"escape\": 0.45335927239726814, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.3553, \"times_seen\": 153.0}, {\"site\": 1216, \"mutant\": \"C\", \"escape\": 0.38259256569311595, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.3015, \"times_seen\": 136.0}, {\"site\": 1216, \"mutant\": \"D\", \"escape\": 0.04822155144527503, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.747, \"times_seen\": 89.0}, {\"site\": 1216, \"mutant\": \"E\", \"escape\": -0.23685493504434063, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.219, \"times_seen\": 52.0}, {\"site\": 1216, \"mutant\": \"F\", \"escape\": 0.006589149337636518, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.0226, \"times_seen\": 32.0}, {\"site\": 1216, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1216, \"mutant\": \"H\", \"escape\": -0.08934406200147009, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.5841, \"times_seen\": 20.0}, {\"site\": 1216, \"mutant\": \"I\", \"escape\": 0.03263519300640555, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.1738, \"times_seen\": 43.0}, {\"site\": 1216, \"mutant\": \"K\", \"escape\": 0.13384510556617976, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -1.1434, \"times_seen\": 27.0}, {\"site\": 1216, \"mutant\": \"L\", \"escape\": -4.193186198607631, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.0576, \"times_seen\": 87.0}, {\"site\": 1216, \"mutant\": \"M\", \"escape\": 0.026411327478057144, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.1474, \"times_seen\": 22.0}, {\"site\": 1216, \"mutant\": \"N\", \"escape\": -0.015780435620178786, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.1172, \"times_seen\": 28.0}, {\"site\": 1216, \"mutant\": \"P\", \"escape\": -0.07292950357865657, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.8864, \"times_seen\": 48.0}, {\"site\": 1216, \"mutant\": \"Q\", \"escape\": -0.1099901518234791, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.063, \"times_seen\": 24.0}, {\"site\": 1216, \"mutant\": \"R\", \"escape\": -0.017972867590099088, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -1.5016, \"times_seen\": 105.0}, {\"site\": 1216, \"mutant\": \"S\", \"escape\": -0.6537655218595403, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": 0.0718, \"times_seen\": 263.0}, {\"site\": 1216, \"mutant\": \"T\", \"escape\": 0.14441509788905194, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.0003, \"times_seen\": 56.0}, {\"site\": 1216, \"mutant\": \"V\", \"escape\": -0.012032611334536671, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.0735, \"times_seen\": 166.0}, {\"site\": 1216, \"mutant\": \"W\", \"escape\": -0.03234820238706623, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.1293, \"times_seen\": 51.0}, {\"site\": 1216, \"mutant\": \"Y\", \"escape\": 0.7420628755763174, \"epitope\": \"epitope 1\", \"reference_site\": \"1219\", \"functional effect\": -0.5349, \"times_seen\": 27.0}, {\"site\": 1217, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1217, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 1217, \"mutant\": \"F\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1217, \"mutant\": \"I\", \"escape\": 0.07996476327442821, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.1032, \"times_seen\": 79.0}, {\"site\": 1217, \"mutant\": \"L\", \"escape\": -0.013192422667010583, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.0528, \"times_seen\": 26.0}, {\"site\": 1217, \"mutant\": \"S\", \"escape\": -0.044879773180207874, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -2.1484, \"times_seen\": 11.0}, {\"site\": 1217, \"mutant\": \"V\", \"escape\": 0.010263556236188333, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -1.2837, \"times_seen\": 4.0}, {\"site\": 1217, \"mutant\": \"Y\", \"escape\": -0.005144992787809705, \"epitope\": \"epitope 1\", \"reference_site\": \"1220\", \"functional effect\": -0.9808, \"times_seen\": 2.0}, {\"site\": 1218, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1218, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1218, \"mutant\": \"L\", \"escape\": 0.03913465172188961, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": 0.065, \"times_seen\": 36.0}, {\"site\": 1218, \"mutant\": \"M\", \"escape\": -0.009344976657887605, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.1515, \"times_seen\": 48.0}, {\"site\": 1218, \"mutant\": \"N\", \"escape\": -0.01733655850920657, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.4276, \"times_seen\": 6.0}, {\"site\": 1218, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.4574, \"times_seen\": null}, {\"site\": 1218, \"mutant\": \"T\", \"escape\": 0.6256118634585255, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.0778, \"times_seen\": 52.0}, {\"site\": 1218, \"mutant\": \"V\", \"escape\": -0.6616034715284101, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -0.1469, \"times_seen\": 133.0}, {\"site\": 1218, \"mutant\": \"Y\", \"escape\": -0.017599211753826113, \"epitope\": \"epitope 1\", \"reference_site\": \"1221\", \"functional effect\": -1.1376, \"times_seen\": 23.0}, {\"site\": 1219, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1219, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1219, \"mutant\": \"D\", \"escape\": 0.006980042972351165, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.2087, \"times_seen\": 5.0}, {\"site\": 1219, \"mutant\": \"P\", \"escape\": 0.006264712533596606, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.1067, \"times_seen\": 1.0}, {\"site\": 1219, \"mutant\": \"S\", \"escape\": 0.01644378717054416, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": 0.0033, \"times_seen\": 39.0}, {\"site\": 1219, \"mutant\": \"T\", \"escape\": 0.2446246306938714, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": -0.0723, \"times_seen\": 95.0}, {\"site\": 1219, \"mutant\": \"V\", \"escape\": 0.4456379978345606, \"epitope\": \"epitope 1\", \"reference_site\": \"1222\", \"functional effect\": -0.6226, \"times_seen\": 79.0}, {\"site\": 1220, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -2.9327, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"A\", \"escape\": 0.014290047525525915, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.387, \"times_seen\": 1.0}, {\"site\": 1220, \"mutant\": \"C\", \"escape\": -0.001254281412532054, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.4959, \"times_seen\": 29.0}, {\"site\": 1220, \"mutant\": \"E\", \"escape\": -0.010654536281641539, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -1.5139, \"times_seen\": 11.0}, {\"site\": 1220, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"R\", \"escape\": -0.08933546319375552, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -2.5374, \"times_seen\": 22.0}, {\"site\": 1220, \"mutant\": \"S\", \"escape\": 0.00010433604174544609, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.6865, \"times_seen\": 41.0}, {\"site\": 1220, \"mutant\": \"V\", \"escape\": -0.0356408917976993, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -0.8444, \"times_seen\": 19.0}, {\"site\": 1220, \"mutant\": \"W\", \"escape\": 0.033834046646332216, \"epitope\": \"epitope 1\", \"reference_site\": \"1223\", \"functional effect\": -1.0369, \"times_seen\": 19.0}, {\"site\": 1221, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1221, \"mutant\": \"F\", \"escape\": -0.06640340106900798, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.2175, \"times_seen\": 34.0}, {\"site\": 1221, \"mutant\": \"I\", \"escape\": -0.009372047677355826, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1221, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1221, \"mutant\": \"M\", \"escape\": -0.0488690769109345, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.0817, \"times_seen\": 24.0}, {\"site\": 1221, \"mutant\": \"P\", \"escape\": 0.007283874452535826, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -1.9729, \"times_seen\": 1.0}, {\"site\": 1221, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 1221, \"mutant\": \"S\", \"escape\": -0.028549564631307447, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.298, \"times_seen\": 44.0}, {\"site\": 1221, \"mutant\": \"V\", \"escape\": -0.02307654040385554, \"epitope\": \"epitope 1\", \"reference_site\": \"1224\", \"functional effect\": -0.2853, \"times_seen\": 16.0}, {\"site\": 1222, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1222, \"mutant\": \"F\", \"escape\": 0.013118855984107357, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.1961, \"times_seen\": 50.0}, {\"site\": 1222, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1222, \"mutant\": \"L\", \"escape\": 0.0694779090462134, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.0194, \"times_seen\": 17.0}, {\"site\": 1222, \"mutant\": \"M\", \"escape\": 0.35720985246812476, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.2032, \"times_seen\": 21.0}, {\"site\": 1222, \"mutant\": \"N\", \"escape\": 0.012973930117982183, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.173, \"times_seen\": 3.0}, {\"site\": 1222, \"mutant\": \"S\", \"escape\": -0.01232865470327902, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.2097, \"times_seen\": 19.0}, {\"site\": 1222, \"mutant\": \"T\", \"escape\": 0.052559271536832, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.1205, \"times_seen\": 16.0}, {\"site\": 1222, \"mutant\": \"V\", \"escape\": -0.0045866274407390046, \"epitope\": \"epitope 1\", \"reference_site\": \"1225\", \"functional effect\": 0.1733, \"times_seen\": 40.0}, {\"site\": 1223, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1223, \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1223, \"mutant\": \"E\", \"escape\": 0.0003895676594198645, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -1.1596, \"times_seen\": 5.0}, {\"site\": 1223, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.4402, \"times_seen\": null}, {\"site\": 1223, \"mutant\": \"S\", \"escape\": -0.0012173315264307914, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.3103, \"times_seen\": 21.0}, {\"site\": 1223, \"mutant\": \"T\", \"escape\": -0.5170888143850672, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.0057, \"times_seen\": 66.0}, {\"site\": 1223, \"mutant\": \"V\", \"escape\": 0.1452640976322935, \"epitope\": \"epitope 1\", \"reference_site\": \"1226\", \"functional effect\": -0.1725, \"times_seen\": 94.0}, {\"site\": 1224, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -1.7015, \"times_seen\": null}, {\"site\": 1224, \"mutant\": \"F\", \"escape\": -0.0020648474217416593, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -2.3523, \"times_seen\": 1.0}, {\"site\": 1224, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1224, \"mutant\": \"K\", \"escape\": -0.016901612887293107, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -2.8078, \"times_seen\": 7.0}, {\"site\": 1224, \"mutant\": \"L\", \"escape\": 0.0010674010643633989, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.6899, \"times_seen\": 13.0}, {\"site\": 1224, \"mutant\": \"M\", \"escape\": 0.46990615245341816, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.1915, \"times_seen\": 77.0}, {\"site\": 1224, \"mutant\": \"N\", \"escape\": -0.01705051289967936, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -1.8437, \"times_seen\": 3.0}, {\"site\": 1224, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -1.1773, \"times_seen\": null}, {\"site\": 1224, \"mutant\": \"T\", \"escape\": -0.031556502573463485, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.466, \"times_seen\": 13.0}, {\"site\": 1224, \"mutant\": \"V\", \"escape\": 0.06943066882269915, \"epitope\": \"epitope 1\", \"reference_site\": \"1227\", \"functional effect\": -0.2212, \"times_seen\": 41.0}, {\"site\": 1225, \"mutant\": \"*\", \"escape\": 0.01921743561191191, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -2.4181, \"times_seen\": 10.0}, {\"site\": 1225, \"mutant\": \"-\", \"escape\": 0.024417635486828203, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -1.0511, \"times_seen\": 1.0}, {\"site\": 1225, \"mutant\": \"A\", \"escape\": -0.007508307244426094, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0799, \"times_seen\": 139.0}, {\"site\": 1225, \"mutant\": \"C\", \"escape\": -0.22002741613474266, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.0272, \"times_seen\": 55.0}, {\"site\": 1225, \"mutant\": \"D\", \"escape\": 1.1095863722863935, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -1.5675, \"times_seen\": 37.0}, {\"site\": 1225, \"mutant\": \"E\", \"escape\": -1.4470281466267205, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -1.0143, \"times_seen\": 89.0}, {\"site\": 1225, \"mutant\": \"F\", \"escape\": 0.22476158803993446, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.1416, \"times_seen\": 65.0}, {\"site\": 1225, \"mutant\": \"G\", \"escape\": 0.012424225368441219, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.1317, \"times_seen\": 139.0}, {\"site\": 1225, \"mutant\": \"H\", \"escape\": 0.009909350974582705, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.8873, \"times_seen\": 39.0}, {\"site\": 1225, \"mutant\": \"I\", \"escape\": 0.17683517721827835, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0404, \"times_seen\": 95.0}, {\"site\": 1225, \"mutant\": \"K\", \"escape\": -0.04928234820764078, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.7357, \"times_seen\": 42.0}, {\"site\": 1225, \"mutant\": \"L\", \"escape\": 0.05527408652823393, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0479, \"times_seen\": 209.0}, {\"site\": 1225, \"mutant\": \"M\", \"escape\": -0.17403141324290822, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0496, \"times_seen\": 59.0}, {\"site\": 1225, \"mutant\": \"N\", \"escape\": -0.0412891109716284, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.8236, \"times_seen\": 33.0}, {\"site\": 1225, \"mutant\": \"P\", \"escape\": -1.2368827309059451, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.7, \"times_seen\": 66.0}, {\"site\": 1225, \"mutant\": \"Q\", \"escape\": -0.5277732821400214, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.7127, \"times_seen\": 46.0}, {\"site\": 1225, \"mutant\": \"R\", \"escape\": -0.01566119431889745, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -2.7184, \"times_seen\": 47.0}, {\"site\": 1225, \"mutant\": \"S\", \"escape\": 0.04547933940970322, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.1117, \"times_seen\": 95.0}, {\"site\": 1225, \"mutant\": \"T\", \"escape\": 0.18434949520573743, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.1155, \"times_seen\": 92.0}, {\"site\": 1225, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1225, \"mutant\": \"W\", \"escape\": 0.0281484342809496, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.3215, \"times_seen\": 55.0}, {\"site\": 1225, \"mutant\": \"Y\", \"escape\": -0.04577336325604934, \"epitope\": \"epitope 1\", \"reference_site\": \"1228\", \"functional effect\": -0.723, \"times_seen\": 45.0}, {\"site\": 1226, \"mutant\": \"-\", \"escape\": 0.02105807281696406, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1226, \"mutant\": \"I\", \"escape\": 0.02011340898837235, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.2766, \"times_seen\": 98.0}, {\"site\": 1226, \"mutant\": \"K\", \"escape\": -0.009308211627311613, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": 0.2572, \"times_seen\": 2.0}, {\"site\": 1226, \"mutant\": \"L\", \"escape\": -0.8174249889249856, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.1168, \"times_seen\": 41.0}, {\"site\": 1226, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1226, \"mutant\": \"R\", \"escape\": -0.006994651913818207, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -1.5001, \"times_seen\": 1.0}, {\"site\": 1226, \"mutant\": \"T\", \"escape\": -0.10152932407265265, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": 0.0645, \"times_seen\": 57.0}, {\"site\": 1226, \"mutant\": \"V\", \"escape\": 0.009968579679554501, \"epitope\": \"epitope 1\", \"reference_site\": \"1229\", \"functional effect\": -0.2728, \"times_seen\": 81.0}, {\"site\": 1227, \"mutant\": \"-\", \"escape\": -0.011440486693028232, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1227, \"mutant\": \"A\", \"escape\": -0.016374016149572845, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0708, \"times_seen\": 16.0}, {\"site\": 1227, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -2.0124, \"times_seen\": null}, {\"site\": 1227, \"mutant\": \"G\", \"escape\": 0.022719331822470778, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0254, \"times_seen\": 14.0}, {\"site\": 1227, \"mutant\": \"L\", \"escape\": -0.028171080291677413, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0927, \"times_seen\": 43.0}, {\"site\": 1227, \"mutant\": \"M\", \"escape\": -0.1463776469559733, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": -0.0999, \"times_seen\": 48.0}, {\"site\": 1227, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1230\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1228, \"mutant\": \"-\", \"escape\": -0.014888861658421914, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1228, \"mutant\": \"A\", \"escape\": 0.04022886574312511, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": 0.1554, \"times_seen\": 49.0}, {\"site\": 1228, \"mutant\": \"I\", \"escape\": -0.640820198482113, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": -0.5252, \"times_seen\": 53.0}, {\"site\": 1228, \"mutant\": \"K\", \"escape\": 0.004657308775761041, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": -1.7746, \"times_seen\": 17.0}, {\"site\": 1228, \"mutant\": \"S\", \"escape\": -0.013269442101402979, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": 0.3093, \"times_seen\": 8.0}, {\"site\": 1228, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1231\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1229, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.882, \"times_seen\": null}, {\"site\": 1229, \"mutant\": \"F\", \"escape\": -0.006959112540436859, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.1186, \"times_seen\": 8.0}, {\"site\": 1229, \"mutant\": \"I\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1229, \"mutant\": \"K\", \"escape\": -0.011721913652625862, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": 0.0471, \"times_seen\": 4.0}, {\"site\": 1229, \"mutant\": \"L\", \"escape\": -0.005995805148277035, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.1578, \"times_seen\": 15.0}, {\"site\": 1229, \"mutant\": \"M\", \"escape\": -0.00680775449354623, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.1257, \"times_seen\": 2.0}, {\"site\": 1229, \"mutant\": \"S\", \"escape\": 0.009434024756468604, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.4748, \"times_seen\": 14.0}, {\"site\": 1229, \"mutant\": \"T\", \"escape\": 0.02210269077337663, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": -0.2131, \"times_seen\": 31.0}, {\"site\": 1229, \"mutant\": \"V\", \"escape\": -0.02578624903130376, \"epitope\": \"epitope 1\", \"reference_site\": \"1232\", \"functional effect\": 0.0215, \"times_seen\": 40.0}, {\"site\": 1230, \"mutant\": \"-\", \"escape\": -0.004225815012240396, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": 0.3177, \"times_seen\": 1.0}, {\"site\": 1230, \"mutant\": \"I\", \"escape\": 0.04225491244169438, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.0475, \"times_seen\": 125.0}, {\"site\": 1230, \"mutant\": \"K\", \"escape\": -0.006939085394196978, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -1.3499, \"times_seen\": 1.0}, {\"site\": 1230, \"mutant\": \"L\", \"escape\": -0.08599404135505843, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.0947, \"times_seen\": 26.0}, {\"site\": 1230, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1230, \"mutant\": \"Q\", \"escape\": 0.027175342344519852, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.8916, \"times_seen\": 5.0}, {\"site\": 1230, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -1.8772, \"times_seen\": null}, {\"site\": 1230, \"mutant\": \"T\", \"escape\": -0.005434732372992111, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": -0.1748, \"times_seen\": 52.0}, {\"site\": 1230, \"mutant\": \"V\", \"escape\": -0.05893002445475015, \"epitope\": \"epitope 1\", \"reference_site\": \"1233\", \"functional effect\": 0.0275, \"times_seen\": 99.0}, {\"site\": 1231, \"mutant\": \"-\", \"escape\": -0.004098951743549419, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1231, \"mutant\": \"F\", \"escape\": -0.0008289318172407666, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.1091, \"times_seen\": 32.0}, {\"site\": 1231, \"mutant\": \"I\", \"escape\": -0.0007642722807737404, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.0854, \"times_seen\": 11.0}, {\"site\": 1231, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1231, \"mutant\": \"M\", \"escape\": -0.00022204474537012377, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.1194, \"times_seen\": 9.0}, {\"site\": 1231, \"mutant\": \"P\", \"escape\": -0.062168613456684035, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.6804, \"times_seen\": 25.0}, {\"site\": 1231, \"mutant\": \"Q\", \"escape\": -0.007522231771231737, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.7067, \"times_seen\": 3.0}, {\"site\": 1231, \"mutant\": \"R\", \"escape\": 0.012198845135590029, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -2.3997, \"times_seen\": 1.0}, {\"site\": 1231, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1234\", \"functional effect\": -0.2956, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"*\", \"escape\": -0.004648494254985879, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -2.6874, \"times_seen\": 2.0}, {\"site\": 1232, \"mutant\": \"-\", \"escape\": -0.008041391569147969, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -2.8968, \"times_seen\": 4.0}, {\"site\": 1232, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"F\", \"escape\": 0.009649153514877506, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.1193, \"times_seen\": 71.0}, {\"site\": 1232, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.0671, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"L\", \"escape\": -0.07458292467236015, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.0483, \"times_seen\": 17.0}, {\"site\": 1232, \"mutant\": \"R\", \"escape\": -0.0039046433836762333, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -1.224, \"times_seen\": 1.0}, {\"site\": 1232, \"mutant\": \"S\", \"escape\": -0.019750612923520847, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.4282, \"times_seen\": 29.0}, {\"site\": 1232, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -0.5153, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"W\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -1.4835, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"Y\", \"escape\": -0.0329605868175422, \"epitope\": \"epitope 1\", \"reference_site\": \"1235\", \"functional effect\": -1.4152, \"times_seen\": 8.0}, {\"site\": 1233, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -1.6538, \"times_seen\": null}, {\"site\": 1233, \"mutant\": \"-\", \"escape\": -0.0068510358574595046, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 1233, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1233, \"mutant\": \"F\", \"escape\": 0.3547374244274436, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -0.4074, \"times_seen\": 50.0}, {\"site\": 1233, \"mutant\": \"R\", \"escape\": 0.007182698923593447, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -1.1882, \"times_seen\": 3.0}, {\"site\": 1233, \"mutant\": \"S\", \"escape\": -0.39682007225923055, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -0.4697, \"times_seen\": 55.0}, {\"site\": 1233, \"mutant\": \"Y\", \"escape\": -0.004281048585383621, \"epitope\": \"epitope 1\", \"reference_site\": \"1236\", \"functional effect\": -1.3228, \"times_seen\": 57.0}, {\"site\": 1234, \"mutant\": \"-\", \"escape\": -0.0024384113373113326, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1234, \"mutant\": \"I\", \"escape\": -0.019389270861813475, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": 0.0143, \"times_seen\": 86.0}, {\"site\": 1234, \"mutant\": \"K\", \"escape\": 0.006586480299301935, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -1.6031, \"times_seen\": 30.0}, {\"site\": 1234, \"mutant\": \"L\", \"escape\": -0.0788848597413071, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -0.0706, \"times_seen\": 29.0}, {\"site\": 1234, \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1234, \"mutant\": \"R\", \"escape\": -0.0021914845310417055, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -1.1254, \"times_seen\": 1.0}, {\"site\": 1234, \"mutant\": \"T\", \"escape\": 0.3683802703719184, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -0.4804, \"times_seen\": 61.0}, {\"site\": 1234, \"mutant\": \"V\", \"escape\": -0.13830364185017258, \"epitope\": \"epitope 1\", \"reference_site\": \"1237\", \"functional effect\": -0.032, \"times_seen\": 81.0}, {\"site\": 1235, \"mutant\": \"-\", \"escape\": -0.026928794025955258, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1235, \"mutant\": \"A\", \"escape\": -0.040476057904493004, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -0.0204, \"times_seen\": 38.0}, {\"site\": 1235, \"mutant\": \"I\", \"escape\": -0.17062398207247664, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -0.004, \"times_seen\": 106.0}, {\"site\": 1235, \"mutant\": \"N\", \"escape\": -2.7355121656685726, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -1.0371, \"times_seen\": 69.0}, {\"site\": 1235, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": -0.5267, \"times_seen\": null}, {\"site\": 1235, \"mutant\": \"S\", \"escape\": -0.031084991589592048, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": 0.0467, \"times_seen\": 38.0}, {\"site\": 1235, \"mutant\": \"T\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1238\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1236, \"mutant\": \"-\", \"escape\": -0.007369524506040404, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.8685, \"times_seen\": 5.0}, {\"site\": 1236, \"mutant\": \"A\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -2.9838, \"times_seen\": null}, {\"site\": 1236, \"mutant\": \"C\", \"escape\": 0.04152957280925844, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.1208, \"times_seen\": 55.0}, {\"site\": 1236, \"mutant\": \"F\", \"escape\": -0.009606220344270984, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -1.3003, \"times_seen\": 4.0}, {\"site\": 1236, \"mutant\": \"G\", \"escape\": -0.07794442076794496, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.2297, \"times_seen\": 60.0}, {\"site\": 1236, \"mutant\": \"I\", \"escape\": -0.9817455971497107, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.5828, \"times_seen\": 49.0}, {\"site\": 1236, \"mutant\": \"N\", \"escape\": -0.006414693445377858, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.3604, \"times_seen\": 31.0}, {\"site\": 1236, \"mutant\": \"P\", \"escape\": 1.658951743349668, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -1.0785, \"times_seen\": 21.0}, {\"site\": 1236, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1236, \"mutant\": \"T\", \"escape\": -0.7205155927837791, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": 0.0624, \"times_seen\": 114.0}, {\"site\": 1236, \"mutant\": \"Y\", \"escape\": -0.027166472652856852, \"epitope\": \"epitope 1\", \"reference_site\": \"1239\", \"functional effect\": -0.2845, \"times_seen\": 3.0}, {\"site\": 1237, \"mutant\": \"*\", \"escape\": -0.0021244218428239435, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -2.0316, \"times_seen\": 3.0}, {\"site\": 1237, \"mutant\": \"-\", \"escape\": -0.005576074213595313, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.6744, \"times_seen\": 9.0}, {\"site\": 1237, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1237, \"mutant\": \"F\", \"escape\": -0.0858964571084686, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.1106, \"times_seen\": 25.0}, {\"site\": 1237, \"mutant\": \"G\", \"escape\": 0.06691905410049206, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.5082, \"times_seen\": 16.0}, {\"site\": 1237, \"mutant\": \"R\", \"escape\": 0.0020104492240217344, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -1.4729, \"times_seen\": 32.0}, {\"site\": 1237, \"mutant\": \"S\", \"escape\": -0.013499978224416257, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -1.1017, \"times_seen\": 14.0}, {\"site\": 1237, \"mutant\": \"Y\", \"escape\": 0.04271807530572134, \"epitope\": \"epitope 1\", \"reference_site\": \"1240\", \"functional effect\": -0.9946, \"times_seen\": 28.0}, {\"site\": 1238, \"mutant\": \"*\", \"escape\": -0.023079893830838548, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -1.7553, \"times_seen\": 4.0}, {\"site\": 1238, \"mutant\": \"-\", \"escape\": -0.0073108113584980745, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": 0.1308, \"times_seen\": 9.0}, {\"site\": 1238, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1238, \"mutant\": \"F\", \"escape\": 1.341779572251479, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.2409, \"times_seen\": 22.0}, {\"site\": 1238, \"mutant\": \"G\", \"escape\": -0.003129438121411356, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -2.1346, \"times_seen\": 1.0}, {\"site\": 1238, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.8018, \"times_seen\": null}, {\"site\": 1238, \"mutant\": \"R\", \"escape\": -0.010520437602177296, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -1.4508, \"times_seen\": 10.0}, {\"site\": 1238, \"mutant\": \"S\", \"escape\": -0.008314905981686669, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.5981, \"times_seen\": 14.0}, {\"site\": 1238, \"mutant\": \"W\", \"escape\": -0.002552516818068328, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.7344, \"times_seen\": 1.0}, {\"site\": 1238, \"mutant\": \"Y\", \"escape\": -1.0393738791902916, \"epitope\": \"epitope 1\", \"reference_site\": \"1241\", \"functional effect\": -0.7287, \"times_seen\": 76.0}, {\"site\": 1239, \"mutant\": \"-\", \"escape\": -0.001992166004126196, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.0966, \"times_seen\": 8.0}, {\"site\": 1239, \"mutant\": \"A\", \"escape\": 0.000384919431594442, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.1894, \"times_seen\": 1.0}, {\"site\": 1239, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.2083, \"times_seen\": null}, {\"site\": 1239, \"mutant\": \"F\", \"escape\": -0.0070226861679845015, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.2464, \"times_seen\": 10.0}, {\"site\": 1239, \"mutant\": \"G\", \"escape\": 0.3043093866191403, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.1266, \"times_seen\": 30.0}, {\"site\": 1239, \"mutant\": \"I\", \"escape\": 0.030584394170804864, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.0166, \"times_seen\": 66.0}, {\"site\": 1239, \"mutant\": \"K\", \"escape\": 0.004481464600833745, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.1954, \"times_seen\": 1.0}, {\"site\": 1239, \"mutant\": \"N\", \"escape\": 0.6485805211793854, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -0.3422, \"times_seen\": 64.0}, {\"site\": 1239, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": -1.4432, \"times_seen\": null}, {\"site\": 1239, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1239, \"mutant\": \"T\", \"escape\": 0.011602538357091324, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.1987, \"times_seen\": 64.0}, {\"site\": 1239, \"mutant\": \"Y\", \"escape\": 0.10393778052909111, \"epitope\": \"epitope 1\", \"reference_site\": \"1242\", \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 1240, \"mutant\": \"*\", \"escape\": 0.013681937869443472, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -1.052, \"times_seen\": 1.0}, {\"site\": 1240, \"mutant\": \"-\", \"escape\": -0.004651776598518839, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1240, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1240, \"mutant\": \"F\", \"escape\": 0.08093980316110032, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.1029, \"times_seen\": 41.0}, {\"site\": 1240, \"mutant\": \"G\", \"escape\": -0.0005248621810938355, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.3107, \"times_seen\": 1.0}, {\"site\": 1240, \"mutant\": \"R\", \"escape\": -0.3071052936486009, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.8646, \"times_seen\": 24.0}, {\"site\": 1240, \"mutant\": \"S\", \"escape\": -0.0200159626171243, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.1091, \"times_seen\": 7.0}, {\"site\": 1240, \"mutant\": \"V\", \"escape\": 0.14469009408929306, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.324, \"times_seen\": 15.0}, {\"site\": 1240, \"mutant\": \"W\", \"escape\": 0.12771663223201632, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.3527, \"times_seen\": 53.0}, {\"site\": 1240, \"mutant\": \"Y\", \"escape\": -0.02103451301026383, \"epitope\": \"epitope 1\", \"reference_site\": \"1243\", \"functional effect\": -0.5323, \"times_seen\": 48.0}, {\"site\": 1241, \"mutant\": \"-\", \"escape\": -0.005455992667351517, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1241, \"mutant\": \"F\", \"escape\": 0.003485221381347638, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.1396, \"times_seen\": 30.0}, {\"site\": 1241, \"mutant\": \"I\", \"escape\": -0.0153734689952438, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.0979, \"times_seen\": 11.0}, {\"site\": 1241, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1241, \"mutant\": \"M\", \"escape\": 0.020230659843793283, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.1033, \"times_seen\": 9.0}, {\"site\": 1241, \"mutant\": \"P\", \"escape\": -0.3092236568070821, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.8224, \"times_seen\": 56.0}, {\"site\": 1241, \"mutant\": \"Q\", \"escape\": -0.010621984210571719, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.5007, \"times_seen\": 3.0}, {\"site\": 1241, \"mutant\": \"R\", \"escape\": -0.004068997767540521, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": 0.2253, \"times_seen\": 1.0}, {\"site\": 1241, \"mutant\": \"V\", \"escape\": -0.02721023617870524, \"epitope\": \"epitope 1\", \"reference_site\": \"1244\", \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 1242, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -1.5664, \"times_seen\": null}, {\"site\": 1242, \"mutant\": \"-\", \"escape\": -0.009363402453898464, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1242, \"mutant\": \"E\", \"escape\": -0.00979128969489684, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.2488, \"times_seen\": 37.0}, {\"site\": 1242, \"mutant\": \"G\", \"escape\": -0.009234618686676764, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 1242, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -2.3704, \"times_seen\": null}, {\"site\": 1242, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1242, \"mutant\": \"M\", \"escape\": -0.9015390559046706, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": 0.0314, \"times_seen\": 28.0}, {\"site\": 1242, \"mutant\": \"N\", \"escape\": -0.6121357313806338, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.0857, \"times_seen\": 57.0}, {\"site\": 1242, \"mutant\": \"Q\", \"escape\": 0.02593730732176767, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.6612, \"times_seen\": 4.0}, {\"site\": 1242, \"mutant\": \"R\", \"escape\": 0.026666801076334904, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.0745, \"times_seen\": 79.0}, {\"site\": 1242, \"mutant\": \"T\", \"escape\": -0.056065524586102956, \"epitope\": \"epitope 1\", \"reference_site\": \"1245\", \"functional effect\": -0.2072, \"times_seen\": 14.0}, {\"site\": 1243, \"mutant\": \"-\", \"escape\": -0.00289260558622018, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": 0.1697, \"times_seen\": 6.0}, {\"site\": 1243, \"mutant\": \"A\", \"escape\": 0.0009312426280458857, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": 0.1369, \"times_seen\": 1.0}, {\"site\": 1243, \"mutant\": \"C\", \"escape\": 0.06998172171439627, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.1513, \"times_seen\": 72.0}, {\"site\": 1243, \"mutant\": \"D\", \"escape\": -0.10868615246922415, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.2387, \"times_seen\": 105.0}, {\"site\": 1243, \"mutant\": \"F\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.3658, \"times_seen\": null}, {\"site\": 1243, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1243, \"mutant\": \"S\", \"escape\": 0.24431366409100844, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.0637, \"times_seen\": 71.0}, {\"site\": 1243, \"mutant\": \"V\", \"escape\": 0.000718746769135013, \"epitope\": \"epitope 1\", \"reference_site\": \"1246\", \"functional effect\": -0.2773, \"times_seen\": 68.0}, {\"site\": 1244, \"mutant\": \"*\", \"escape\": -0.0008291752157194003, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.5813, \"times_seen\": 1.0}, {\"site\": 1244, \"mutant\": \"-\", \"escape\": -0.00011087112168125373, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -1.9998, \"times_seen\": 1.0}, {\"site\": 1244, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1244, \"mutant\": \"F\", \"escape\": -0.03491509662711095, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.3644, \"times_seen\": 62.0}, {\"site\": 1244, \"mutant\": \"G\", \"escape\": 0.011180895371489436, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.8924, \"times_seen\": 2.0}, {\"site\": 1244, \"mutant\": \"L\", \"escape\": -0.04437876134442167, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.138, \"times_seen\": 24.0}, {\"site\": 1244, \"mutant\": \"R\", \"escape\": 0.027975710433949287, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.551, \"times_seen\": 31.0}, {\"site\": 1244, \"mutant\": \"S\", \"escape\": 0.8349036182262285, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.3998, \"times_seen\": 43.0}, {\"site\": 1244, \"mutant\": \"W\", \"escape\": 0.3017658374489514, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.3368, \"times_seen\": 26.0}, {\"site\": 1244, \"mutant\": \"Y\", \"escape\": -0.005108792207288087, \"epitope\": \"epitope 1\", \"reference_site\": \"1247\", \"functional effect\": -0.815, \"times_seen\": 37.0}, {\"site\": 1245, \"mutant\": \"*\", \"escape\": -0.004228972808653238, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.4376, \"times_seen\": 1.0}, {\"site\": 1245, \"mutant\": \"-\", \"escape\": 0.00847349066288828, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": 0.2266, \"times_seen\": 1.0}, {\"site\": 1245, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1245, \"mutant\": \"F\", \"escape\": 0.14381217287978104, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.1572, \"times_seen\": 69.0}, {\"site\": 1245, \"mutant\": \"G\", \"escape\": -0.018738816145526443, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.5566, \"times_seen\": 16.0}, {\"site\": 1245, \"mutant\": \"L\", \"escape\": -0.010195180381842622, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.0698, \"times_seen\": 28.0}, {\"site\": 1245, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.5006, \"times_seen\": null}, {\"site\": 1245, \"mutant\": \"R\", \"escape\": -0.2767776526463697, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.342, \"times_seen\": 32.0}, {\"site\": 1245, \"mutant\": \"S\", \"escape\": 0.00043480231668329843, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.321, \"times_seen\": 16.0}, {\"site\": 1245, \"mutant\": \"V\", \"escape\": -0.10165826076614148, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.3538, \"times_seen\": 29.0}, {\"site\": 1245, \"mutant\": \"W\", \"escape\": -0.03886364508924522, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.1295, \"times_seen\": 44.0}, {\"site\": 1245, \"mutant\": \"Y\", \"escape\": -0.04013668976550012, \"epitope\": \"epitope 1\", \"reference_site\": \"1248\", \"functional effect\": -0.4627, \"times_seen\": 85.0}, {\"site\": 1246, \"mutant\": \"-\", \"escape\": 0.014114638884665015, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.7342, \"times_seen\": 2.0}, {\"site\": 1246, \"mutant\": \"A\", \"escape\": -0.03458728247585757, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.005, \"times_seen\": 26.0}, {\"site\": 1246, \"mutant\": \"C\", \"escape\": -0.0345036626548113, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.0657, \"times_seen\": 36.0}, {\"site\": 1246, \"mutant\": \"F\", \"escape\": 0.02882920088698187, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.1038, \"times_seen\": 92.0}, {\"site\": 1246, \"mutant\": \"L\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.079, \"times_seen\": null}, {\"site\": 1246, \"mutant\": \"P\", \"escape\": 0.45163888212660336, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.219, \"times_seen\": 45.0}, {\"site\": 1246, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1246, \"mutant\": \"T\", \"escape\": -0.017948237535728603, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": 0.2124, \"times_seen\": 30.0}, {\"site\": 1246, \"mutant\": \"V\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": -0.0951, \"times_seen\": null}, {\"site\": 1246, \"mutant\": \"Y\", \"escape\": 0.0032420943015758173, \"epitope\": \"epitope 1\", \"reference_site\": \"1249\", \"functional effect\": 0.096, \"times_seen\": 30.0}, {\"site\": 1247, \"mutant\": \"*\", \"escape\": -0.0067277541241249385, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1247, \"mutant\": \"-\", \"escape\": 0.007863051418673092, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.3928, \"times_seen\": 2.0}, {\"site\": 1247, \"mutant\": \"C\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1247, \"mutant\": \"F\", \"escape\": 0.4824701285225079, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.0678, \"times_seen\": 122.0}, {\"site\": 1247, \"mutant\": \"G\", \"escape\": -0.9359527436448558, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.4042, \"times_seen\": 11.0}, {\"site\": 1247, \"mutant\": \"L\", \"escape\": -0.4862927107591264, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.086, \"times_seen\": 26.0}, {\"site\": 1247, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.4455, \"times_seen\": null}, {\"site\": 1247, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.6552, \"times_seen\": null}, {\"site\": 1247, \"mutant\": \"R\", \"escape\": 0.059117079959212226, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": 0.0299, \"times_seen\": 99.0}, {\"site\": 1247, \"mutant\": \"S\", \"escape\": 0.012180841974338724, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.3167, \"times_seen\": 41.0}, {\"site\": 1247, \"mutant\": \"W\", \"escape\": -0.09793756092309124, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.0876, \"times_seen\": 45.0}, {\"site\": 1247, \"mutant\": \"Y\", \"escape\": -1.004503071446396, \"epitope\": \"epitope 1\", \"reference_site\": \"1250\", \"functional effect\": -0.0012, \"times_seen\": 125.0}, {\"site\": 1248, \"mutant\": \"-\", \"escape\": 0.013007245922225923, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": -0.2543, \"times_seen\": 2.0}, {\"site\": 1248, \"mutant\": \"A\", \"escape\": -0.014475815184742521, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0212, \"times_seen\": 9.0}, {\"site\": 1248, \"mutant\": \"C\", \"escape\": -0.006525347064766663, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.4135, \"times_seen\": 3.0}, {\"site\": 1248, \"mutant\": \"D\", \"escape\": -0.01877857763936433, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.1186, \"times_seen\": 40.0}, {\"site\": 1248, \"mutant\": \"E\", \"escape\": 0.20180522790439825, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0622, \"times_seen\": 55.0}, {\"site\": 1248, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1248, \"mutant\": \"L\", \"escape\": -0.0020728858344813204, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.1906, \"times_seen\": 1.0}, {\"site\": 1248, \"mutant\": \"R\", \"escape\": 0.03953914239619634, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.2094, \"times_seen\": 63.0}, {\"site\": 1248, \"mutant\": \"S\", \"escape\": -0.011641379445094026, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.3219, \"times_seen\": 18.0}, {\"site\": 1248, \"mutant\": \"V\", \"escape\": -0.01074777814391635, \"epitope\": \"epitope 1\", \"reference_site\": \"1251\", \"functional effect\": 0.0905, \"times_seen\": 67.0}, {\"site\": 1249, \"mutant\": \"*\", \"escape\": -0.019249818008157886, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.0346, \"times_seen\": 49.0}, {\"site\": 1249, \"mutant\": \"-\", \"escape\": 0.007574654498661827, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1249, \"mutant\": \"A\", \"escape\": 0.006760093774005301, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.0001, \"times_seen\": 81.0}, {\"site\": 1249, \"mutant\": \"C\", \"escape\": -0.5411533566690594, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3963, \"times_seen\": 143.0}, {\"site\": 1249, \"mutant\": \"D\", \"escape\": 0.03108808821357416, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.1111, \"times_seen\": 45.0}, {\"site\": 1249, \"mutant\": \"E\", \"escape\": -0.04656892192524851, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.0168, \"times_seen\": 30.0}, {\"site\": 1249, \"mutant\": \"F\", \"escape\": 0.004252414706626662, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.397, \"times_seen\": 141.0}, {\"site\": 1249, \"mutant\": \"G\", \"escape\": 0.17395968206917395, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.4074, \"times_seen\": 94.0}, {\"site\": 1249, \"mutant\": \"H\", \"escape\": 0.13720545808749285, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2924, \"times_seen\": 41.0}, {\"site\": 1249, \"mutant\": \"I\", \"escape\": -0.06319781396690968, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.4224, \"times_seen\": 50.0}, {\"site\": 1249, \"mutant\": \"K\", \"escape\": -1.102146972245514, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.1965, \"times_seen\": 40.0}, {\"site\": 1249, \"mutant\": \"L\", \"escape\": -0.15827055839566165, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3611, \"times_seen\": 101.0}, {\"site\": 1249, \"mutant\": \"M\", \"escape\": -0.013170630825822833, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2764, \"times_seen\": 31.0}, {\"site\": 1249, \"mutant\": \"N\", \"escape\": 0.014287837887405378, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.397, \"times_seen\": 36.0}, {\"site\": 1249, \"mutant\": \"P\", \"escape\": -0.002843553975856657, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2155, \"times_seen\": 158.0}, {\"site\": 1249, \"mutant\": \"Q\", \"escape\": 0.016849418873180134, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3237, \"times_seen\": 25.0}, {\"site\": 1249, \"mutant\": \"R\", \"escape\": 0.05150309713945824, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2863, \"times_seen\": 95.0}, {\"site\": 1249, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1249, \"mutant\": \"T\", \"escape\": -0.015678519849620313, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": -0.2164, \"times_seen\": 136.0}, {\"site\": 1249, \"mutant\": \"V\", \"escape\": -0.1499053497711417, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.3255, \"times_seen\": 99.0}, {\"site\": 1249, \"mutant\": \"W\", \"escape\": -0.0031460701116438404, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.2297, \"times_seen\": 29.0}, {\"site\": 1249, \"mutant\": \"Y\", \"escape\": -1.9616222097798282, \"epitope\": \"epitope 1\", \"reference_site\": \"1252\", \"functional effect\": 0.4444, \"times_seen\": 126.0}, {\"site\": 1250, \"mutant\": \"*\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": -0.3058, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"L\", \"escape\": -0.010702887183445052, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.3678, \"times_seen\": 5.0}, {\"site\": 1250, \"mutant\": \"R\", \"escape\": -0.0023761254228813113, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.397, \"times_seen\": 62.0}, {\"site\": 1250, \"mutant\": \"S\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"W\", \"escape\": -0.011349055872608838, \"epitope\": \"epitope 1\", \"reference_site\": \"1253\", \"functional effect\": 0.397, \"times_seen\": 2.0}], \"data-fec33ae205ff6712775e4252a9254f06\": [{\"site\": 1, \"wildtype\": \"M\", \"_stat_site_order\": 0}, {\"site\": 2, \"wildtype\": \"F\", \"_stat_site_order\": 1}, {\"site\": 3, \"wildtype\": \"V\", \"_stat_site_order\": 2}, {\"site\": 4, \"wildtype\": \"F\", \"_stat_site_order\": 3}, {\"site\": 5, \"wildtype\": \"L\", \"_stat_site_order\": 4}, {\"site\": 6, \"wildtype\": \"V\", \"_stat_site_order\": 5}, {\"site\": 7, \"wildtype\": \"L\", \"_stat_site_order\": 6}, {\"site\": 8, \"wildtype\": \"L\", \"_stat_site_order\": 7}, {\"site\": 9, \"wildtype\": \"P\", \"_stat_site_order\": 8}, {\"site\": 10, \"wildtype\": \"L\", \"_stat_site_order\": 9}, {\"site\": 11, \"wildtype\": \"V\", \"_stat_site_order\": 10}, {\"site\": 12, \"wildtype\": \"S\", \"_stat_site_order\": 11}, {\"site\": 13, \"wildtype\": \"S\", \"_stat_site_order\": 12}, {\"site\": 14, \"wildtype\": \"Q\", \"_stat_site_order\": 13}, {\"site\": 15, \"wildtype\": \"C\", \"_stat_site_order\": 14}, {\"site\": 16, \"wildtype\": \"V\", \"_stat_site_order\": 15}, {\"site\": 17, \"wildtype\": \"N\", \"_stat_site_order\": 16}, {\"site\": 18, \"wildtype\": \"L\", \"_stat_site_order\": 17}, {\"site\": 19, \"wildtype\": \"T\", \"_stat_site_order\": 18}, {\"site\": 20, \"wildtype\": \"T\", \"_stat_site_order\": 19}, {\"site\": 21, \"wildtype\": \"R\", \"_stat_site_order\": 20}, {\"site\": 22, \"wildtype\": \"T\", \"_stat_site_order\": 21}, {\"site\": 23, \"wildtype\": \"Q\", \"_stat_site_order\": 22}, {\"site\": 24, \"wildtype\": \"L\", \"_stat_site_order\": 23}, {\"site\": 25, \"wildtype\": \"P\", \"_stat_site_order\": 24}, {\"site\": 26, \"wildtype\": \"P\", \"_stat_site_order\": 25}, {\"site\": 27, \"wildtype\": \"A\", \"_stat_site_order\": 26}, {\"site\": 28, \"wildtype\": \"Y\", \"_stat_site_order\": 27}, {\"site\": 29, \"wildtype\": \"T\", \"_stat_site_order\": 28}, {\"site\": 30, \"wildtype\": \"N\", \"_stat_site_order\": 29}, {\"site\": 31, \"wildtype\": \"S\", \"_stat_site_order\": 30}, {\"site\": 32, \"wildtype\": \"F\", \"_stat_site_order\": 31}, {\"site\": 33, \"wildtype\": \"T\", \"_stat_site_order\": 32}, {\"site\": 34, \"wildtype\": \"R\", \"_stat_site_order\": 33}, {\"site\": 35, \"wildtype\": \"G\", \"_stat_site_order\": 34}, {\"site\": 36, \"wildtype\": \"V\", \"_stat_site_order\": 35}, {\"site\": 37, \"wildtype\": \"Y\", \"_stat_site_order\": 36}, {\"site\": 38, \"wildtype\": \"Y\", \"_stat_site_order\": 37}, {\"site\": 39, \"wildtype\": \"P\", \"_stat_site_order\": 38}, {\"site\": 40, \"wildtype\": \"D\", \"_stat_site_order\": 39}, {\"site\": 41, \"wildtype\": \"K\", \"_stat_site_order\": 40}, {\"site\": 42, \"wildtype\": \"V\", \"_stat_site_order\": 41}, {\"site\": 43, \"wildtype\": \"F\", \"_stat_site_order\": 42}, {\"site\": 44, \"wildtype\": \"R\", \"_stat_site_order\": 43}, {\"site\": 45, \"wildtype\": \"S\", \"_stat_site_order\": 44}, {\"site\": 46, \"wildtype\": \"S\", \"_stat_site_order\": 45}, {\"site\": 47, \"wildtype\": \"V\", \"_stat_site_order\": 46}, {\"site\": 48, \"wildtype\": \"L\", \"_stat_site_order\": 47}, {\"site\": 49, \"wildtype\": \"H\", \"_stat_site_order\": 48}, {\"site\": 50, \"wildtype\": \"S\", \"_stat_site_order\": 49}, {\"site\": 51, \"wildtype\": \"T\", \"_stat_site_order\": 50}, {\"site\": 52, \"wildtype\": \"Q\", \"_stat_site_order\": 51}, {\"site\": 53, \"wildtype\": \"D\", \"_stat_site_order\": 52}, {\"site\": 54, \"wildtype\": \"L\", \"_stat_site_order\": 53}, {\"site\": 55, \"wildtype\": \"F\", \"_stat_site_order\": 54}, {\"site\": 56, \"wildtype\": \"L\", \"_stat_site_order\": 55}, {\"site\": 57, \"wildtype\": \"P\", \"_stat_site_order\": 56}, {\"site\": 58, \"wildtype\": \"F\", \"_stat_site_order\": 57}, {\"site\": 59, \"wildtype\": \"F\", \"_stat_site_order\": 58}, {\"site\": 60, \"wildtype\": \"S\", \"_stat_site_order\": 59}, {\"site\": 61, \"wildtype\": \"N\", \"_stat_site_order\": 60}, {\"site\": 62, \"wildtype\": \"V\", \"_stat_site_order\": 61}, {\"site\": 63, \"wildtype\": \"T\", \"_stat_site_order\": 62}, {\"site\": 64, \"wildtype\": \"W\", \"_stat_site_order\": 63}, {\"site\": 65, \"wildtype\": \"F\", \"_stat_site_order\": 64}, {\"site\": 66, \"wildtype\": \"H\", \"_stat_site_order\": 65}, {\"site\": 67, \"wildtype\": \"V\", \"_stat_site_order\": 66}, {\"site\": 68, \"wildtype\": \"I\", \"_stat_site_order\": 67}, {\"site\": 69, \"wildtype\": \"S\", \"_stat_site_order\": 68}, {\"site\": 70, \"wildtype\": \"G\", \"_stat_site_order\": 69}, {\"site\": 71, \"wildtype\": \"T\", \"_stat_site_order\": 70}, {\"site\": 72, \"wildtype\": \"N\", \"_stat_site_order\": 71}, {\"site\": 73, \"wildtype\": \"G\", \"_stat_site_order\": 72}, {\"site\": 74, \"wildtype\": \"T\", \"_stat_site_order\": 73}, {\"site\": 75, \"wildtype\": \"K\", \"_stat_site_order\": 74}, {\"site\": 76, \"wildtype\": \"R\", \"_stat_site_order\": 75}, {\"site\": 77, \"wildtype\": \"F\", \"_stat_site_order\": 76}, {\"site\": 78, \"wildtype\": \"D\", \"_stat_site_order\": 77}, {\"site\": 79, \"wildtype\": \"N\", \"_stat_site_order\": 78}, {\"site\": 80, \"wildtype\": \"P\", \"_stat_site_order\": 79}, {\"site\": 81, \"wildtype\": \"V\", \"_stat_site_order\": 80}, {\"site\": 82, \"wildtype\": \"L\", \"_stat_site_order\": 81}, {\"site\": 83, \"wildtype\": \"P\", \"_stat_site_order\": 82}, {\"site\": 84, \"wildtype\": \"F\", \"_stat_site_order\": 83}, {\"site\": 85, \"wildtype\": \"N\", \"_stat_site_order\": 84}, {\"site\": 86, \"wildtype\": \"D\", \"_stat_site_order\": 85}, {\"site\": 87, \"wildtype\": \"G\", \"_stat_site_order\": 86}, {\"site\": 88, \"wildtype\": \"V\", \"_stat_site_order\": 87}, {\"site\": 89, \"wildtype\": \"Y\", \"_stat_site_order\": 88}, {\"site\": 90, \"wildtype\": \"F\", \"_stat_site_order\": 89}, {\"site\": 91, \"wildtype\": \"A\", \"_stat_site_order\": 90}, {\"site\": 92, \"wildtype\": \"S\", \"_stat_site_order\": 91}, {\"site\": 93, \"wildtype\": \"I\", \"_stat_site_order\": 92}, {\"site\": 94, \"wildtype\": \"E\", \"_stat_site_order\": 93}, {\"site\": 95, \"wildtype\": \"K\", \"_stat_site_order\": 94}, {\"site\": 96, \"wildtype\": \"S\", \"_stat_site_order\": 95}, {\"site\": 97, \"wildtype\": \"N\", \"_stat_site_order\": 96}, {\"site\": 98, \"wildtype\": \"I\", \"_stat_site_order\": 97}, {\"site\": 99, \"wildtype\": \"I\", \"_stat_site_order\": 98}, {\"site\": 100, \"wildtype\": \"R\", \"_stat_site_order\": 99}, {\"site\": 101, \"wildtype\": \"G\", \"_stat_site_order\": 100}, {\"site\": 102, \"wildtype\": \"W\", \"_stat_site_order\": 101}, {\"site\": 103, \"wildtype\": \"I\", \"_stat_site_order\": 102}, {\"site\": 104, \"wildtype\": \"F\", \"_stat_site_order\": 103}, {\"site\": 105, \"wildtype\": \"G\", \"_stat_site_order\": 104}, {\"site\": 106, \"wildtype\": \"T\", \"_stat_site_order\": 105}, {\"site\": 107, \"wildtype\": \"T\", \"_stat_site_order\": 106}, {\"site\": 108, \"wildtype\": \"L\", \"_stat_site_order\": 107}, {\"site\": 109, \"wildtype\": \"D\", \"_stat_site_order\": 108}, {\"site\": 110, \"wildtype\": \"S\", \"_stat_site_order\": 109}, {\"site\": 111, \"wildtype\": \"K\", \"_stat_site_order\": 110}, {\"site\": 112, \"wildtype\": \"T\", \"_stat_site_order\": 111}, {\"site\": 113, \"wildtype\": \"Q\", \"_stat_site_order\": 112}, {\"site\": 114, \"wildtype\": \"S\", \"_stat_site_order\": 113}, {\"site\": 115, \"wildtype\": \"L\", \"_stat_site_order\": 114}, {\"site\": 116, \"wildtype\": \"L\", \"_stat_site_order\": 115}, {\"site\": 117, \"wildtype\": \"I\", \"_stat_site_order\": 116}, {\"site\": 118, \"wildtype\": \"V\", \"_stat_site_order\": 117}, {\"site\": 119, \"wildtype\": \"N\", \"_stat_site_order\": 118}, {\"site\": 120, \"wildtype\": \"N\", \"_stat_site_order\": 119}, {\"site\": 121, \"wildtype\": \"A\", \"_stat_site_order\": 120}, {\"site\": 122, \"wildtype\": \"T\", \"_stat_site_order\": 121}, {\"site\": 123, \"wildtype\": \"N\", \"_stat_site_order\": 122}, {\"site\": 124, \"wildtype\": \"V\", \"_stat_site_order\": 123}, {\"site\": 125, \"wildtype\": \"V\", \"_stat_site_order\": 124}, {\"site\": 126, \"wildtype\": \"I\", \"_stat_site_order\": 125}, {\"site\": 127, \"wildtype\": \"K\", \"_stat_site_order\": 126}, {\"site\": 128, \"wildtype\": \"V\", \"_stat_site_order\": 127}, {\"site\": 129, \"wildtype\": \"C\", \"_stat_site_order\": 128}, {\"site\": 130, \"wildtype\": \"E\", \"_stat_site_order\": 129}, {\"site\": 131, \"wildtype\": \"F\", \"_stat_site_order\": 130}, {\"site\": 132, \"wildtype\": \"Q\", \"_stat_site_order\": 131}, {\"site\": 133, \"wildtype\": \"F\", \"_stat_site_order\": 132}, {\"site\": 134, \"wildtype\": \"C\", \"_stat_site_order\": 133}, {\"site\": 135, \"wildtype\": \"N\", \"_stat_site_order\": 134}, {\"site\": 136, \"wildtype\": \"D\", \"_stat_site_order\": 135}, {\"site\": 137, \"wildtype\": \"P\", \"_stat_site_order\": 136}, {\"site\": 138, \"wildtype\": \"F\", \"_stat_site_order\": 137}, {\"site\": 139, \"wildtype\": \"L\", \"_stat_site_order\": 138}, {\"site\": 140, \"wildtype\": \"D\", \"_stat_site_order\": 139}, {\"site\": 141, \"wildtype\": \"H\", \"_stat_site_order\": 140}, {\"site\": 142, \"wildtype\": \"K\", \"_stat_site_order\": 141}, {\"site\": 143, \"wildtype\": \"N\", \"_stat_site_order\": 142}, {\"site\": 144, \"wildtype\": \"N\", \"_stat_site_order\": 143}, {\"site\": 145, \"wildtype\": \"K\", \"_stat_site_order\": 144}, {\"site\": 146, \"wildtype\": \"S\", \"_stat_site_order\": 145}, {\"site\": 147, \"wildtype\": \"W\", \"_stat_site_order\": 146}, {\"site\": 148, \"wildtype\": \"M\", \"_stat_site_order\": 147}, {\"site\": 149, \"wildtype\": \"E\", \"_stat_site_order\": 148}, {\"site\": 150, \"wildtype\": \"S\", \"_stat_site_order\": 149}, {\"site\": 151, \"wildtype\": \"E\", \"_stat_site_order\": 150}, {\"site\": 152, \"wildtype\": \"F\", \"_stat_site_order\": 151}, {\"site\": 153, \"wildtype\": \"R\", \"_stat_site_order\": 152}, {\"site\": 154, \"wildtype\": \"V\", \"_stat_site_order\": 153}, {\"site\": 155, \"wildtype\": \"Y\", \"_stat_site_order\": 154}, {\"site\": 156, \"wildtype\": \"S\", \"_stat_site_order\": 155}, {\"site\": 157, \"wildtype\": \"S\", \"_stat_site_order\": 156}, {\"site\": 158, \"wildtype\": \"A\", \"_stat_site_order\": 157}, {\"site\": 159, \"wildtype\": \"N\", \"_stat_site_order\": 158}, {\"site\": 160, \"wildtype\": \"N\", \"_stat_site_order\": 159}, {\"site\": 161, \"wildtype\": \"C\", \"_stat_site_order\": 160}, {\"site\": 162, \"wildtype\": \"T\", \"_stat_site_order\": 161}, {\"site\": 163, \"wildtype\": \"F\", \"_stat_site_order\": 162}, {\"site\": 164, \"wildtype\": \"E\", \"_stat_site_order\": 163}, {\"site\": 165, \"wildtype\": \"Y\", \"_stat_site_order\": 164}, {\"site\": 166, \"wildtype\": \"V\", \"_stat_site_order\": 165}, {\"site\": 167, \"wildtype\": \"S\", \"_stat_site_order\": 166}, {\"site\": 168, \"wildtype\": \"Q\", \"_stat_site_order\": 167}, {\"site\": 169, \"wildtype\": \"P\", \"_stat_site_order\": 168}, {\"site\": 170, \"wildtype\": \"F\", \"_stat_site_order\": 169}, {\"site\": 171, \"wildtype\": \"L\", \"_stat_site_order\": 170}, {\"site\": 172, \"wildtype\": \"M\", \"_stat_site_order\": 171}, {\"site\": 173, \"wildtype\": \"D\", \"_stat_site_order\": 172}, {\"site\": 174, \"wildtype\": \"L\", \"_stat_site_order\": 173}, {\"site\": 175, \"wildtype\": \"E\", \"_stat_site_order\": 174}, {\"site\": 176, \"wildtype\": \"G\", \"_stat_site_order\": 175}, {\"site\": 177, \"wildtype\": \"K\", \"_stat_site_order\": 176}, {\"site\": 178, \"wildtype\": \"Q\", \"_stat_site_order\": 177}, {\"site\": 179, \"wildtype\": \"G\", \"_stat_site_order\": 178}, {\"site\": 180, \"wildtype\": \"N\", \"_stat_site_order\": 179}, {\"site\": 181, \"wildtype\": \"F\", \"_stat_site_order\": 180}, {\"site\": 182, \"wildtype\": \"K\", \"_stat_site_order\": 181}, {\"site\": 183, \"wildtype\": \"N\", \"_stat_site_order\": 182}, {\"site\": 184, \"wildtype\": \"L\", \"_stat_site_order\": 183}, {\"site\": 185, \"wildtype\": \"R\", \"_stat_site_order\": 184}, {\"site\": 186, \"wildtype\": \"E\", \"_stat_site_order\": 185}, {\"site\": 187, \"wildtype\": \"F\", \"_stat_site_order\": 186}, {\"site\": 188, \"wildtype\": \"V\", \"_stat_site_order\": 187}, {\"site\": 189, \"wildtype\": \"F\", \"_stat_site_order\": 188}, {\"site\": 190, \"wildtype\": \"K\", \"_stat_site_order\": 189}, {\"site\": 191, \"wildtype\": \"N\", \"_stat_site_order\": 190}, {\"site\": 192, \"wildtype\": \"I\", \"_stat_site_order\": 191}, {\"site\": 193, \"wildtype\": \"D\", \"_stat_site_order\": 192}, {\"site\": 194, \"wildtype\": \"G\", \"_stat_site_order\": 193}, {\"site\": 195, \"wildtype\": \"Y\", \"_stat_site_order\": 194}, {\"site\": 196, \"wildtype\": \"F\", \"_stat_site_order\": 195}, {\"site\": 197, \"wildtype\": \"K\", \"_stat_site_order\": 196}, {\"site\": 198, \"wildtype\": \"I\", \"_stat_site_order\": 197}, {\"site\": 199, \"wildtype\": \"Y\", \"_stat_site_order\": 198}, {\"site\": 200, \"wildtype\": \"S\", \"_stat_site_order\": 199}, {\"site\": 201, \"wildtype\": \"K\", \"_stat_site_order\": 200}, {\"site\": 202, \"wildtype\": \"H\", \"_stat_site_order\": 201}, {\"site\": 203, \"wildtype\": \"T\", \"_stat_site_order\": 202}, {\"site\": 204, \"wildtype\": \"P\", \"_stat_site_order\": 203}, {\"site\": 205, \"wildtype\": \"I\", \"_stat_site_order\": 204}, {\"site\": 206, \"wildtype\": \"I\", \"_stat_site_order\": 205}, {\"site\": 207, \"wildtype\": \"V\", \"_stat_site_order\": 206}, {\"site\": 208, \"wildtype\": \"R\", \"_stat_site_order\": 207}, {\"site\": 209, \"wildtype\": \"E\", \"_stat_site_order\": 208}, {\"site\": 210, \"wildtype\": \"P\", \"_stat_site_order\": 209}, {\"site\": 211, \"wildtype\": \"E\", \"_stat_site_order\": 210}, {\"site\": 212, \"wildtype\": \"D\", \"_stat_site_order\": 211}, {\"site\": 213, \"wildtype\": \"L\", \"_stat_site_order\": 212}, {\"site\": 214, \"wildtype\": \"P\", \"_stat_site_order\": 213}, {\"site\": 215, \"wildtype\": \"Q\", \"_stat_site_order\": 214}, {\"site\": 216, \"wildtype\": \"G\", \"_stat_site_order\": 215}, {\"site\": 217, \"wildtype\": \"F\", \"_stat_site_order\": 216}, {\"site\": 218, \"wildtype\": \"S\", \"_stat_site_order\": 217}, {\"site\": 219, \"wildtype\": \"A\", \"_stat_site_order\": 218}, {\"site\": 220, \"wildtype\": \"L\", \"_stat_site_order\": 219}, {\"site\": 221, \"wildtype\": \"E\", \"_stat_site_order\": 220}, {\"site\": 222, \"wildtype\": \"P\", \"_stat_site_order\": 221}, {\"site\": 223, \"wildtype\": \"L\", \"_stat_site_order\": 222}, {\"site\": 224, \"wildtype\": \"V\", \"_stat_site_order\": 223}, {\"site\": 225, \"wildtype\": \"D\", \"_stat_site_order\": 224}, {\"site\": 226, \"wildtype\": \"L\", \"_stat_site_order\": 225}, {\"site\": 227, \"wildtype\": \"P\", \"_stat_site_order\": 226}, {\"site\": 228, \"wildtype\": \"I\", \"_stat_site_order\": 227}, {\"site\": 229, \"wildtype\": \"G\", \"_stat_site_order\": 228}, {\"site\": 230, \"wildtype\": \"I\", \"_stat_site_order\": 229}, {\"site\": 231, \"wildtype\": \"N\", \"_stat_site_order\": 230}, {\"site\": 232, \"wildtype\": \"I\", \"_stat_site_order\": 231}, {\"site\": 233, \"wildtype\": \"T\", \"_stat_site_order\": 232}, {\"site\": 234, \"wildtype\": \"R\", \"_stat_site_order\": 233}, {\"site\": 235, \"wildtype\": \"F\", \"_stat_site_order\": 234}, {\"site\": 236, \"wildtype\": \"Q\", \"_stat_site_order\": 235}, {\"site\": 237, \"wildtype\": \"T\", \"_stat_site_order\": 236}, {\"site\": 238, \"wildtype\": \"L\", \"_stat_site_order\": 237}, {\"site\": 239, \"wildtype\": \"L\", \"_stat_site_order\": 238}, {\"site\": 240, \"wildtype\": \"A\", \"_stat_site_order\": 239}, {\"site\": 241, \"wildtype\": \"L\", \"_stat_site_order\": 240}, {\"site\": 242, \"wildtype\": \"H\", \"_stat_site_order\": 241}, {\"site\": 243, \"wildtype\": \"R\", \"_stat_site_order\": 242}, {\"site\": 244, \"wildtype\": \"S\", \"_stat_site_order\": 243}, {\"site\": 245, \"wildtype\": \"Y\", \"_stat_site_order\": 244}, {\"site\": 246, \"wildtype\": \"L\", \"_stat_site_order\": 245}, {\"site\": 247, \"wildtype\": \"T\", \"_stat_site_order\": 246}, {\"site\": 248, \"wildtype\": \"P\", \"_stat_site_order\": 247}, {\"site\": 249, \"wildtype\": \"G\", \"_stat_site_order\": 248}, {\"site\": 250, \"wildtype\": \"D\", \"_stat_site_order\": 249}, {\"site\": 251, \"wildtype\": \"S\", \"_stat_site_order\": 250}, {\"site\": 252, \"wildtype\": \"S\", \"_stat_site_order\": 251}, {\"site\": 253, \"wildtype\": \"S\", \"_stat_site_order\": 252}, {\"site\": 254, \"wildtype\": \"G\", \"_stat_site_order\": 253}, {\"site\": 255, \"wildtype\": \"W\", \"_stat_site_order\": 254}, {\"site\": 256, \"wildtype\": \"T\", \"_stat_site_order\": 255}, {\"site\": 257, \"wildtype\": \"A\", \"_stat_site_order\": 256}, {\"site\": 258, \"wildtype\": \"G\", \"_stat_site_order\": 257}, {\"site\": 259, \"wildtype\": \"A\", \"_stat_site_order\": 258}, {\"site\": 260, \"wildtype\": \"A\", \"_stat_site_order\": 259}, {\"site\": 261, \"wildtype\": \"A\", \"_stat_site_order\": 260}, {\"site\": 262, \"wildtype\": \"Y\", \"_stat_site_order\": 261}, {\"site\": 263, \"wildtype\": \"Y\", \"_stat_site_order\": 262}, {\"site\": 264, \"wildtype\": \"V\", \"_stat_site_order\": 263}, {\"site\": 265, \"wildtype\": \"G\", \"_stat_site_order\": 264}, {\"site\": 266, \"wildtype\": \"Y\", \"_stat_site_order\": 265}, {\"site\": 267, \"wildtype\": \"L\", \"_stat_site_order\": 266}, {\"site\": 268, \"wildtype\": \"Q\", \"_stat_site_order\": 267}, {\"site\": 269, \"wildtype\": \"P\", \"_stat_site_order\": 268}, {\"site\": 270, \"wildtype\": \"R\", \"_stat_site_order\": 269}, {\"site\": 271, \"wildtype\": \"T\", \"_stat_site_order\": 270}, {\"site\": 272, \"wildtype\": \"F\", \"_stat_site_order\": 271}, {\"site\": 273, \"wildtype\": \"L\", \"_stat_site_order\": 272}, {\"site\": 274, \"wildtype\": \"L\", \"_stat_site_order\": 273}, {\"site\": 275, \"wildtype\": \"K\", \"_stat_site_order\": 274}, {\"site\": 276, \"wildtype\": \"Y\", \"_stat_site_order\": 275}, {\"site\": 277, \"wildtype\": \"N\", \"_stat_site_order\": 276}, {\"site\": 278, \"wildtype\": \"E\", \"_stat_site_order\": 277}, {\"site\": 279, \"wildtype\": \"N\", \"_stat_site_order\": 278}, {\"site\": 280, \"wildtype\": \"G\", \"_stat_site_order\": 279}, {\"site\": 281, \"wildtype\": \"T\", \"_stat_site_order\": 280}, {\"site\": 282, \"wildtype\": \"I\", \"_stat_site_order\": 281}, {\"site\": 283, \"wildtype\": \"T\", \"_stat_site_order\": 282}, {\"site\": 284, \"wildtype\": \"D\", \"_stat_site_order\": 283}, {\"site\": 285, \"wildtype\": \"A\", \"_stat_site_order\": 284}, {\"site\": 286, \"wildtype\": \"V\", \"_stat_site_order\": 285}, {\"site\": 287, \"wildtype\": \"D\", \"_stat_site_order\": 286}, {\"site\": 288, \"wildtype\": \"C\", \"_stat_site_order\": 287}, {\"site\": 289, \"wildtype\": \"A\", \"_stat_site_order\": 288}, {\"site\": 290, \"wildtype\": \"L\", \"_stat_site_order\": 289}, {\"site\": 291, \"wildtype\": \"D\", \"_stat_site_order\": 290}, {\"site\": 292, \"wildtype\": \"P\", \"_stat_site_order\": 291}, {\"site\": 293, \"wildtype\": \"L\", \"_stat_site_order\": 292}, {\"site\": 294, \"wildtype\": \"S\", \"_stat_site_order\": 293}, {\"site\": 295, \"wildtype\": \"E\", \"_stat_site_order\": 294}, {\"site\": 296, \"wildtype\": \"T\", \"_stat_site_order\": 295}, {\"site\": 297, \"wildtype\": \"K\", \"_stat_site_order\": 296}, {\"site\": 298, \"wildtype\": \"C\", \"_stat_site_order\": 297}, {\"site\": 299, \"wildtype\": \"T\", \"_stat_site_order\": 298}, {\"site\": 300, \"wildtype\": \"L\", \"_stat_site_order\": 299}, {\"site\": 301, \"wildtype\": \"K\", \"_stat_site_order\": 300}, {\"site\": 302, \"wildtype\": \"S\", \"_stat_site_order\": 301}, {\"site\": 303, \"wildtype\": \"F\", \"_stat_site_order\": 302}, {\"site\": 304, \"wildtype\": \"T\", \"_stat_site_order\": 303}, {\"site\": 305, \"wildtype\": \"V\", \"_stat_site_order\": 304}, {\"site\": 306, \"wildtype\": \"E\", \"_stat_site_order\": 305}, {\"site\": 307, \"wildtype\": \"K\", \"_stat_site_order\": 306}, {\"site\": 308, \"wildtype\": \"G\", \"_stat_site_order\": 307}, {\"site\": 309, \"wildtype\": \"I\", \"_stat_site_order\": 308}, {\"site\": 310, \"wildtype\": \"Y\", \"_stat_site_order\": 309}, {\"site\": 311, \"wildtype\": \"Q\", \"_stat_site_order\": 310}, {\"site\": 312, \"wildtype\": \"T\", \"_stat_site_order\": 311}, {\"site\": 313, \"wildtype\": \"S\", \"_stat_site_order\": 312}, {\"site\": 314, \"wildtype\": \"N\", \"_stat_site_order\": 313}, {\"site\": 315, \"wildtype\": \"F\", \"_stat_site_order\": 314}, {\"site\": 316, \"wildtype\": \"R\", \"_stat_site_order\": 315}, {\"site\": 317, \"wildtype\": \"V\", \"_stat_site_order\": 316}, {\"site\": 318, \"wildtype\": \"Q\", \"_stat_site_order\": 317}, {\"site\": 319, \"wildtype\": \"P\", \"_stat_site_order\": 318}, {\"site\": 320, \"wildtype\": \"T\", \"_stat_site_order\": 319}, {\"site\": 321, \"wildtype\": \"E\", \"_stat_site_order\": 320}, {\"site\": 322, \"wildtype\": \"S\", \"_stat_site_order\": 321}, {\"site\": 323, \"wildtype\": \"I\", \"_stat_site_order\": 322}, {\"site\": 324, \"wildtype\": \"V\", \"_stat_site_order\": 323}, {\"site\": 325, \"wildtype\": \"R\", \"_stat_site_order\": 324}, {\"site\": 326, \"wildtype\": \"F\", \"_stat_site_order\": 325}, {\"site\": 327, \"wildtype\": \"P\", \"_stat_site_order\": 326}, {\"site\": 328, \"wildtype\": \"N\", \"_stat_site_order\": 327}, {\"site\": 329, \"wildtype\": \"I\", \"_stat_site_order\": 328}, {\"site\": 330, \"wildtype\": \"T\", \"_stat_site_order\": 329}, {\"site\": 331, \"wildtype\": \"N\", \"_stat_site_order\": 330}, {\"site\": 332, \"wildtype\": \"L\", \"_stat_site_order\": 331}, {\"site\": 333, \"wildtype\": \"C\", \"_stat_site_order\": 332}, {\"site\": 334, \"wildtype\": \"P\", \"_stat_site_order\": 333}, {\"site\": 335, \"wildtype\": \"F\", \"_stat_site_order\": 334}, {\"site\": 336, \"wildtype\": \"D\", \"_stat_site_order\": 335}, {\"site\": 337, \"wildtype\": \"E\", \"_stat_site_order\": 336}, {\"site\": 338, \"wildtype\": \"V\", \"_stat_site_order\": 337}, {\"site\": 339, \"wildtype\": \"F\", \"_stat_site_order\": 338}, {\"site\": 340, \"wildtype\": \"N\", \"_stat_site_order\": 339}, {\"site\": 341, \"wildtype\": \"A\", \"_stat_site_order\": 340}, {\"site\": 342, \"wildtype\": \"T\", \"_stat_site_order\": 341}, {\"site\": 343, \"wildtype\": \"R\", \"_stat_site_order\": 342}, {\"site\": 345, \"wildtype\": \"A\", \"_stat_site_order\": 343}, {\"site\": 346, \"wildtype\": \"S\", \"_stat_site_order\": 344}, {\"site\": 347, \"wildtype\": \"V\", \"_stat_site_order\": 345}, {\"site\": 348, \"wildtype\": \"Y\", \"_stat_site_order\": 346}, {\"site\": 349, \"wildtype\": \"A\", \"_stat_site_order\": 347}, {\"site\": 350, \"wildtype\": \"W\", \"_stat_site_order\": 348}, {\"site\": 351, \"wildtype\": \"N\", \"_stat_site_order\": 349}, {\"site\": 352, \"wildtype\": \"R\", \"_stat_site_order\": 350}, {\"site\": 353, \"wildtype\": \"K\", \"_stat_site_order\": 351}, {\"site\": 354, \"wildtype\": \"R\", \"_stat_site_order\": 352}, {\"site\": 355, \"wildtype\": \"I\", \"_stat_site_order\": 353}, {\"site\": 356, \"wildtype\": \"S\", \"_stat_site_order\": 354}, {\"site\": 357, \"wildtype\": \"N\", \"_stat_site_order\": 355}, {\"site\": 358, \"wildtype\": \"C\", \"_stat_site_order\": 356}, {\"site\": 359, \"wildtype\": \"V\", \"_stat_site_order\": 357}, {\"site\": 360, \"wildtype\": \"A\", \"_stat_site_order\": 358}, {\"site\": 361, \"wildtype\": \"D\", \"_stat_site_order\": 359}, {\"site\": 362, \"wildtype\": \"Y\", \"_stat_site_order\": 360}, {\"site\": 363, \"wildtype\": \"S\", \"_stat_site_order\": 361}, {\"site\": 364, \"wildtype\": \"V\", \"_stat_site_order\": 362}, {\"site\": 365, \"wildtype\": \"L\", \"_stat_site_order\": 363}, {\"site\": 366, \"wildtype\": \"Y\", \"_stat_site_order\": 364}, {\"site\": 367, \"wildtype\": \"N\", \"_stat_site_order\": 365}, {\"site\": 368, \"wildtype\": \"L\", \"_stat_site_order\": 366}, {\"site\": 369, \"wildtype\": \"A\", \"_stat_site_order\": 367}, {\"site\": 370, \"wildtype\": \"P\", \"_stat_site_order\": 368}, {\"site\": 371, \"wildtype\": \"F\", \"_stat_site_order\": 369}, {\"site\": 372, \"wildtype\": \"F\", \"_stat_site_order\": 370}, {\"site\": 373, \"wildtype\": \"T\", \"_stat_site_order\": 371}, {\"site\": 374, \"wildtype\": \"F\", \"_stat_site_order\": 372}, {\"site\": 375, \"wildtype\": \"K\", \"_stat_site_order\": 373}, {\"site\": 376, \"wildtype\": \"C\", \"_stat_site_order\": 374}, {\"site\": 377, \"wildtype\": \"Y\", \"_stat_site_order\": 375}, {\"site\": 378, \"wildtype\": \"G\", \"_stat_site_order\": 376}, {\"site\": 379, \"wildtype\": \"V\", \"_stat_site_order\": 377}, {\"site\": 380, \"wildtype\": \"S\", \"_stat_site_order\": 378}, {\"site\": 381, \"wildtype\": \"P\", \"_stat_site_order\": 379}, {\"site\": 382, \"wildtype\": \"T\", \"_stat_site_order\": 380}, {\"site\": 383, \"wildtype\": \"K\", \"_stat_site_order\": 381}, {\"site\": 384, \"wildtype\": \"L\", \"_stat_site_order\": 382}, {\"site\": 385, \"wildtype\": \"N\", \"_stat_site_order\": 383}, {\"site\": 386, \"wildtype\": \"D\", \"_stat_site_order\": 384}, {\"site\": 387, \"wildtype\": \"L\", \"_stat_site_order\": 385}, {\"site\": 388, \"wildtype\": \"C\", \"_stat_site_order\": 386}, {\"site\": 389, \"wildtype\": \"F\", \"_stat_site_order\": 387}, {\"site\": 390, \"wildtype\": \"T\", \"_stat_site_order\": 388}, {\"site\": 391, \"wildtype\": \"N\", \"_stat_site_order\": 389}, {\"site\": 392, \"wildtype\": \"V\", \"_stat_site_order\": 390}, {\"site\": 393, \"wildtype\": \"Y\", \"_stat_site_order\": 391}, {\"site\": 394, \"wildtype\": \"A\", \"_stat_site_order\": 392}, {\"site\": 395, \"wildtype\": \"D\", \"_stat_site_order\": 393}, {\"site\": 396, \"wildtype\": \"S\", \"_stat_site_order\": 394}, {\"site\": 397, \"wildtype\": \"F\", \"_stat_site_order\": 395}, {\"site\": 398, \"wildtype\": \"V\", \"_stat_site_order\": 396}, {\"site\": 399, \"wildtype\": \"I\", \"_stat_site_order\": 397}, {\"site\": 400, \"wildtype\": \"R\", \"_stat_site_order\": 398}, {\"site\": 401, \"wildtype\": \"G\", \"_stat_site_order\": 399}, {\"site\": 402, \"wildtype\": \"D\", \"_stat_site_order\": 400}, {\"site\": 403, \"wildtype\": \"E\", \"_stat_site_order\": 401}, {\"site\": 404, \"wildtype\": \"V\", \"_stat_site_order\": 402}, {\"site\": 405, \"wildtype\": \"R\", \"_stat_site_order\": 403}, {\"site\": 406, \"wildtype\": \"Q\", \"_stat_site_order\": 404}, {\"site\": 407, \"wildtype\": \"I\", \"_stat_site_order\": 405}, {\"site\": 408, \"wildtype\": \"A\", \"_stat_site_order\": 406}, {\"site\": 409, \"wildtype\": \"P\", \"_stat_site_order\": 407}, {\"site\": 410, \"wildtype\": \"G\", \"_stat_site_order\": 408}, {\"site\": 411, \"wildtype\": \"Q\", \"_stat_site_order\": 409}, {\"site\": 412, \"wildtype\": \"T\", \"_stat_site_order\": 410}, {\"site\": 413, \"wildtype\": \"G\", \"_stat_site_order\": 411}, {\"site\": 414, \"wildtype\": \"N\", \"_stat_site_order\": 412}, {\"site\": 415, \"wildtype\": \"I\", \"_stat_site_order\": 413}, {\"site\": 416, \"wildtype\": \"A\", \"_stat_site_order\": 414}, {\"site\": 417, \"wildtype\": \"D\", \"_stat_site_order\": 415}, {\"site\": 418, \"wildtype\": \"Y\", \"_stat_site_order\": 416}, {\"site\": 419, \"wildtype\": \"N\", \"_stat_site_order\": 417}, {\"site\": 420, \"wildtype\": \"Y\", \"_stat_site_order\": 418}, {\"site\": 421, \"wildtype\": \"K\", \"_stat_site_order\": 419}, {\"site\": 422, \"wildtype\": \"L\", \"_stat_site_order\": 420}, {\"site\": 423, \"wildtype\": \"P\", \"_stat_site_order\": 421}, {\"site\": 424, \"wildtype\": \"D\", \"_stat_site_order\": 422}, {\"site\": 425, \"wildtype\": \"D\", \"_stat_site_order\": 423}, {\"site\": 426, \"wildtype\": \"F\", \"_stat_site_order\": 424}, {\"site\": 427, \"wildtype\": \"T\", \"_stat_site_order\": 425}, {\"site\": 428, \"wildtype\": \"G\", \"_stat_site_order\": 426}, {\"site\": 429, \"wildtype\": \"C\", \"_stat_site_order\": 427}, {\"site\": 430, \"wildtype\": \"V\", \"_stat_site_order\": 428}, {\"site\": 431, \"wildtype\": \"I\", \"_stat_site_order\": 429}, {\"site\": 432, \"wildtype\": \"A\", \"_stat_site_order\": 430}, {\"site\": 433, \"wildtype\": \"W\", \"_stat_site_order\": 431}, {\"site\": 434, \"wildtype\": \"N\", \"_stat_site_order\": 432}, {\"site\": 435, \"wildtype\": \"S\", \"_stat_site_order\": 433}, {\"site\": 436, \"wildtype\": \"N\", \"_stat_site_order\": 434}, {\"site\": 437, \"wildtype\": \"K\", \"_stat_site_order\": 435}, {\"site\": 438, \"wildtype\": \"L\", \"_stat_site_order\": 436}, {\"site\": 439, \"wildtype\": \"D\", \"_stat_site_order\": 437}, {\"site\": 440, \"wildtype\": \"S\", \"_stat_site_order\": 438}, {\"site\": 441, \"wildtype\": \"K\", \"_stat_site_order\": 439}, {\"site\": 442, \"wildtype\": \"V\", \"_stat_site_order\": 440}, {\"site\": 443, \"wildtype\": \"S\", \"_stat_site_order\": 441}, {\"site\": 444, \"wildtype\": \"G\", \"_stat_site_order\": 442}, {\"site\": 445, \"wildtype\": \"N\", \"_stat_site_order\": 443}, {\"site\": 446, \"wildtype\": \"Y\", \"_stat_site_order\": 444}, {\"site\": 447, \"wildtype\": \"N\", \"_stat_site_order\": 445}, {\"site\": 448, \"wildtype\": \"Y\", \"_stat_site_order\": 446}, {\"site\": 449, \"wildtype\": \"L\", \"_stat_site_order\": 447}, {\"site\": 450, \"wildtype\": \"Y\", \"_stat_site_order\": 448}, {\"site\": 451, \"wildtype\": \"R\", \"_stat_site_order\": 449}, {\"site\": 452, \"wildtype\": \"L\", \"_stat_site_order\": 450}, {\"site\": 453, \"wildtype\": \"F\", \"_stat_site_order\": 451}, {\"site\": 454, \"wildtype\": \"R\", \"_stat_site_order\": 452}, {\"site\": 455, \"wildtype\": \"K\", \"_stat_site_order\": 453}, {\"site\": 456, \"wildtype\": \"S\", \"_stat_site_order\": 454}, {\"site\": 457, \"wildtype\": \"N\", \"_stat_site_order\": 455}, {\"site\": 458, \"wildtype\": \"L\", \"_stat_site_order\": 456}, {\"site\": 459, \"wildtype\": \"K\", \"_stat_site_order\": 457}, {\"site\": 460, \"wildtype\": \"P\", \"_stat_site_order\": 458}, {\"site\": 461, \"wildtype\": \"F\", \"_stat_site_order\": 459}, {\"site\": 462, \"wildtype\": \"E\", \"_stat_site_order\": 460}, {\"site\": 463, \"wildtype\": \"R\", \"_stat_site_order\": 461}, {\"site\": 464, \"wildtype\": \"D\", \"_stat_site_order\": 462}, {\"site\": 465, \"wildtype\": \"I\", \"_stat_site_order\": 463}, {\"site\": 466, \"wildtype\": \"S\", \"_stat_site_order\": 464}, {\"site\": 467, \"wildtype\": \"T\", \"_stat_site_order\": 465}, {\"site\": 468, \"wildtype\": \"E\", \"_stat_site_order\": 466}, {\"site\": 469, \"wildtype\": \"I\", \"_stat_site_order\": 467}, {\"site\": 470, \"wildtype\": \"Y\", \"_stat_site_order\": 468}, {\"site\": 471, \"wildtype\": \"Q\", \"_stat_site_order\": 469}, {\"site\": 472, \"wildtype\": \"A\", \"_stat_site_order\": 470}, {\"site\": 473, \"wildtype\": \"G\", \"_stat_site_order\": 471}, {\"site\": 474, \"wildtype\": \"N\", \"_stat_site_order\": 472}, {\"site\": 475, \"wildtype\": \"K\", \"_stat_site_order\": 473}, {\"site\": 476, \"wildtype\": \"P\", \"_stat_site_order\": 474}, {\"site\": 477, \"wildtype\": \"C\", \"_stat_site_order\": 475}, {\"site\": 478, \"wildtype\": \"N\", \"_stat_site_order\": 476}, {\"site\": 479, \"wildtype\": \"G\", \"_stat_site_order\": 477}, {\"site\": 480, \"wildtype\": \"V\", \"_stat_site_order\": 478}, {\"site\": 481, \"wildtype\": \"A\", \"_stat_site_order\": 479}, {\"site\": 482, \"wildtype\": \"G\", \"_stat_site_order\": 480}, {\"site\": 483, \"wildtype\": \"F\", \"_stat_site_order\": 481}, {\"site\": 484, \"wildtype\": \"N\", \"_stat_site_order\": 482}, {\"site\": 485, \"wildtype\": \"C\", \"_stat_site_order\": 483}, {\"site\": 486, \"wildtype\": \"Y\", \"_stat_site_order\": 484}, {\"site\": 487, \"wildtype\": \"F\", \"_stat_site_order\": 485}, {\"site\": 488, \"wildtype\": \"P\", \"_stat_site_order\": 486}, {\"site\": 489, \"wildtype\": \"L\", \"_stat_site_order\": 487}, {\"site\": 490, \"wildtype\": \"R\", \"_stat_site_order\": 488}, {\"site\": 491, \"wildtype\": \"S\", \"_stat_site_order\": 489}, {\"site\": 492, \"wildtype\": \"Y\", \"_stat_site_order\": 490}, {\"site\": 493, \"wildtype\": \"S\", \"_stat_site_order\": 491}, {\"site\": 494, \"wildtype\": \"F\", \"_stat_site_order\": 492}, {\"site\": 495, \"wildtype\": \"R\", \"_stat_site_order\": 493}, {\"site\": 496, \"wildtype\": \"P\", \"_stat_site_order\": 494}, {\"site\": 497, \"wildtype\": \"T\", \"_stat_site_order\": 495}, {\"site\": 498, \"wildtype\": \"Y\", \"_stat_site_order\": 496}, {\"site\": 499, \"wildtype\": \"G\", \"_stat_site_order\": 497}, {\"site\": 500, \"wildtype\": \"V\", \"_stat_site_order\": 498}, {\"site\": 501, \"wildtype\": \"G\", \"_stat_site_order\": 499}, {\"site\": 502, \"wildtype\": \"H\", \"_stat_site_order\": 500}, {\"site\": 503, \"wildtype\": \"Q\", \"_stat_site_order\": 501}, {\"site\": 504, \"wildtype\": \"P\", \"_stat_site_order\": 502}, {\"site\": 505, \"wildtype\": \"Y\", \"_stat_site_order\": 503}, {\"site\": 506, \"wildtype\": \"R\", \"_stat_site_order\": 504}, {\"site\": 507, \"wildtype\": \"V\", \"_stat_site_order\": 505}, {\"site\": 508, \"wildtype\": \"V\", \"_stat_site_order\": 506}, {\"site\": 509, \"wildtype\": \"V\", \"_stat_site_order\": 507}, {\"site\": 510, \"wildtype\": \"L\", \"_stat_site_order\": 508}, {\"site\": 511, \"wildtype\": \"S\", \"_stat_site_order\": 509}, {\"site\": 512, \"wildtype\": \"F\", \"_stat_site_order\": 510}, {\"site\": 513, \"wildtype\": \"E\", \"_stat_site_order\": 511}, {\"site\": 514, \"wildtype\": \"L\", \"_stat_site_order\": 512}, {\"site\": 515, \"wildtype\": \"L\", \"_stat_site_order\": 513}, {\"site\": 516, \"wildtype\": \"H\", \"_stat_site_order\": 514}, {\"site\": 517, \"wildtype\": \"A\", \"_stat_site_order\": 515}, {\"site\": 518, \"wildtype\": \"P\", \"_stat_site_order\": 516}, {\"site\": 519, \"wildtype\": \"A\", \"_stat_site_order\": 517}, {\"site\": 520, \"wildtype\": \"T\", \"_stat_site_order\": 518}, {\"site\": 521, \"wildtype\": \"V\", \"_stat_site_order\": 519}, {\"site\": 522, \"wildtype\": \"C\", \"_stat_site_order\": 520}, {\"site\": 523, \"wildtype\": \"G\", \"_stat_site_order\": 521}, {\"site\": 524, \"wildtype\": \"P\", \"_stat_site_order\": 522}, {\"site\": 525, \"wildtype\": \"K\", \"_stat_site_order\": 523}, {\"site\": 526, \"wildtype\": \"K\", \"_stat_site_order\": 524}, {\"site\": 527, \"wildtype\": \"S\", \"_stat_site_order\": 525}, {\"site\": 528, \"wildtype\": \"T\", \"_stat_site_order\": 526}, {\"site\": 529, \"wildtype\": \"N\", \"_stat_site_order\": 527}, {\"site\": 530, \"wildtype\": \"L\", \"_stat_site_order\": 528}, {\"site\": 531, \"wildtype\": \"V\", \"_stat_site_order\": 529}, {\"site\": 532, \"wildtype\": \"K\", \"_stat_site_order\": 530}, {\"site\": 533, \"wildtype\": \"N\", \"_stat_site_order\": 531}, {\"site\": 534, \"wildtype\": \"K\", \"_stat_site_order\": 532}, {\"site\": 535, \"wildtype\": \"C\", \"_stat_site_order\": 533}, {\"site\": 536, \"wildtype\": \"V\", \"_stat_site_order\": 534}, {\"site\": 537, \"wildtype\": \"N\", \"_stat_site_order\": 535}, {\"site\": 538, \"wildtype\": \"F\", \"_stat_site_order\": 536}, {\"site\": 539, \"wildtype\": \"N\", \"_stat_site_order\": 537}, {\"site\": 540, \"wildtype\": \"F\", \"_stat_site_order\": 538}, {\"site\": 541, \"wildtype\": \"N\", \"_stat_site_order\": 539}, {\"site\": 542, \"wildtype\": \"G\", \"_stat_site_order\": 540}, {\"site\": 543, \"wildtype\": \"L\", \"_stat_site_order\": 541}, {\"site\": 544, \"wildtype\": \"K\", \"_stat_site_order\": 542}, {\"site\": 545, \"wildtype\": \"G\", \"_stat_site_order\": 543}, {\"site\": 546, \"wildtype\": \"T\", \"_stat_site_order\": 544}, {\"site\": 547, \"wildtype\": \"G\", \"_stat_site_order\": 545}, {\"site\": 548, \"wildtype\": \"V\", \"_stat_site_order\": 546}, {\"site\": 549, \"wildtype\": \"L\", \"_stat_site_order\": 547}, {\"site\": 550, \"wildtype\": \"T\", \"_stat_site_order\": 548}, {\"site\": 551, \"wildtype\": \"E\", \"_stat_site_order\": 549}, {\"site\": 552, \"wildtype\": \"S\", \"_stat_site_order\": 550}, {\"site\": 553, \"wildtype\": \"N\", \"_stat_site_order\": 551}, {\"site\": 554, \"wildtype\": \"K\", \"_stat_site_order\": 552}, {\"site\": 555, \"wildtype\": \"K\", \"_stat_site_order\": 553}, {\"site\": 556, \"wildtype\": \"F\", \"_stat_site_order\": 554}, {\"site\": 557, \"wildtype\": \"L\", \"_stat_site_order\": 555}, {\"site\": 558, \"wildtype\": \"P\", \"_stat_site_order\": 556}, {\"site\": 559, \"wildtype\": \"F\", \"_stat_site_order\": 557}, {\"site\": 560, \"wildtype\": \"Q\", \"_stat_site_order\": 558}, {\"site\": 561, \"wildtype\": \"Q\", \"_stat_site_order\": 559}, {\"site\": 562, \"wildtype\": \"F\", \"_stat_site_order\": 560}, {\"site\": 563, \"wildtype\": \"G\", \"_stat_site_order\": 561}, {\"site\": 564, \"wildtype\": \"R\", \"_stat_site_order\": 562}, {\"site\": 565, \"wildtype\": \"D\", \"_stat_site_order\": 563}, {\"site\": 566, \"wildtype\": \"I\", \"_stat_site_order\": 564}, {\"site\": 567, \"wildtype\": \"A\", \"_stat_site_order\": 565}, {\"site\": 568, \"wildtype\": \"D\", \"_stat_site_order\": 566}, {\"site\": 569, \"wildtype\": \"T\", \"_stat_site_order\": 567}, {\"site\": 570, \"wildtype\": \"T\", \"_stat_site_order\": 568}, {\"site\": 571, \"wildtype\": \"D\", \"_stat_site_order\": 569}, {\"site\": 572, \"wildtype\": \"A\", \"_stat_site_order\": 570}, {\"site\": 573, \"wildtype\": \"V\", \"_stat_site_order\": 571}, {\"site\": 574, \"wildtype\": \"R\", \"_stat_site_order\": 572}, {\"site\": 575, \"wildtype\": \"D\", \"_stat_site_order\": 573}, {\"site\": 576, \"wildtype\": \"P\", \"_stat_site_order\": 574}, {\"site\": 577, \"wildtype\": \"Q\", \"_stat_site_order\": 575}, {\"site\": 578, \"wildtype\": \"T\", \"_stat_site_order\": 576}, {\"site\": 579, \"wildtype\": \"L\", \"_stat_site_order\": 577}, {\"site\": 580, \"wildtype\": \"E\", \"_stat_site_order\": 578}, {\"site\": 581, \"wildtype\": \"I\", \"_stat_site_order\": 579}, {\"site\": 582, \"wildtype\": \"L\", \"_stat_site_order\": 580}, {\"site\": 583, \"wildtype\": \"D\", \"_stat_site_order\": 581}, {\"site\": 584, \"wildtype\": \"I\", \"_stat_site_order\": 582}, {\"site\": 585, \"wildtype\": \"T\", \"_stat_site_order\": 583}, {\"site\": 586, \"wildtype\": \"P\", \"_stat_site_order\": 584}, {\"site\": 587, \"wildtype\": \"C\", \"_stat_site_order\": 585}, {\"site\": 588, \"wildtype\": \"S\", \"_stat_site_order\": 586}, {\"site\": 589, \"wildtype\": \"F\", \"_stat_site_order\": 587}, {\"site\": 590, \"wildtype\": \"G\", \"_stat_site_order\": 588}, {\"site\": 591, \"wildtype\": \"G\", \"_stat_site_order\": 589}, {\"site\": 592, \"wildtype\": \"V\", \"_stat_site_order\": 590}, {\"site\": 593, \"wildtype\": \"S\", \"_stat_site_order\": 591}, {\"site\": 594, \"wildtype\": \"V\", \"_stat_site_order\": 592}, {\"site\": 595, \"wildtype\": \"I\", \"_stat_site_order\": 593}, {\"site\": 596, \"wildtype\": \"T\", \"_stat_site_order\": 594}, {\"site\": 597, \"wildtype\": \"P\", \"_stat_site_order\": 595}, {\"site\": 598, \"wildtype\": \"G\", \"_stat_site_order\": 596}, {\"site\": 599, \"wildtype\": \"T\", \"_stat_site_order\": 597}, {\"site\": 600, \"wildtype\": \"N\", \"_stat_site_order\": 598}, {\"site\": 601, \"wildtype\": \"T\", \"_stat_site_order\": 599}, {\"site\": 602, \"wildtype\": \"S\", \"_stat_site_order\": 600}, {\"site\": 603, \"wildtype\": \"N\", \"_stat_site_order\": 601}, {\"site\": 604, \"wildtype\": \"Q\", \"_stat_site_order\": 602}, {\"site\": 605, \"wildtype\": \"V\", \"_stat_site_order\": 603}, {\"site\": 606, \"wildtype\": \"A\", \"_stat_site_order\": 604}, {\"site\": 607, \"wildtype\": \"V\", \"_stat_site_order\": 605}, {\"site\": 608, \"wildtype\": \"L\", \"_stat_site_order\": 606}, {\"site\": 609, \"wildtype\": \"Y\", \"_stat_site_order\": 607}, {\"site\": 610, \"wildtype\": \"Q\", \"_stat_site_order\": 608}, {\"site\": 611, \"wildtype\": \"G\", \"_stat_site_order\": 609}, {\"site\": 612, \"wildtype\": \"V\", \"_stat_site_order\": 610}, {\"site\": 613, \"wildtype\": \"N\", \"_stat_site_order\": 611}, {\"site\": 614, \"wildtype\": \"C\", \"_stat_site_order\": 612}, {\"site\": 615, \"wildtype\": \"T\", \"_stat_site_order\": 613}, {\"site\": 616, \"wildtype\": \"E\", \"_stat_site_order\": 614}, {\"site\": 617, \"wildtype\": \"V\", \"_stat_site_order\": 615}, {\"site\": 618, \"wildtype\": \"P\", \"_stat_site_order\": 616}, {\"site\": 619, \"wildtype\": \"V\", \"_stat_site_order\": 617}, {\"site\": 620, \"wildtype\": \"A\", \"_stat_site_order\": 618}, {\"site\": 621, \"wildtype\": \"I\", \"_stat_site_order\": 619}, {\"site\": 622, \"wildtype\": \"H\", \"_stat_site_order\": 620}, {\"site\": 623, \"wildtype\": \"A\", \"_stat_site_order\": 621}, {\"site\": 624, \"wildtype\": \"D\", \"_stat_site_order\": 622}, {\"site\": 625, \"wildtype\": \"Q\", \"_stat_site_order\": 623}, {\"site\": 626, \"wildtype\": \"L\", \"_stat_site_order\": 624}, {\"site\": 627, \"wildtype\": \"T\", \"_stat_site_order\": 625}, {\"site\": 628, \"wildtype\": \"P\", \"_stat_site_order\": 626}, {\"site\": 629, \"wildtype\": \"T\", \"_stat_site_order\": 627}, {\"site\": 630, \"wildtype\": \"W\", \"_stat_site_order\": 628}, {\"site\": 631, \"wildtype\": \"R\", \"_stat_site_order\": 629}, {\"site\": 632, \"wildtype\": \"V\", \"_stat_site_order\": 630}, {\"site\": 633, \"wildtype\": \"Y\", \"_stat_site_order\": 631}, {\"site\": 634, \"wildtype\": \"S\", \"_stat_site_order\": 632}, {\"site\": 635, \"wildtype\": \"T\", \"_stat_site_order\": 633}, {\"site\": 636, \"wildtype\": \"G\", \"_stat_site_order\": 634}, {\"site\": 637, \"wildtype\": \"S\", \"_stat_site_order\": 635}, {\"site\": 638, \"wildtype\": \"N\", \"_stat_site_order\": 636}, {\"site\": 639, \"wildtype\": \"V\", \"_stat_site_order\": 637}, {\"site\": 640, \"wildtype\": \"F\", \"_stat_site_order\": 638}, {\"site\": 641, \"wildtype\": \"Q\", \"_stat_site_order\": 639}, {\"site\": 642, \"wildtype\": \"T\", \"_stat_site_order\": 640}, {\"site\": 643, \"wildtype\": \"R\", \"_stat_site_order\": 641}, {\"site\": 644, \"wildtype\": \"A\", \"_stat_site_order\": 642}, {\"site\": 645, \"wildtype\": \"G\", \"_stat_site_order\": 643}, {\"site\": 646, \"wildtype\": \"C\", \"_stat_site_order\": 644}, {\"site\": 647, \"wildtype\": \"L\", \"_stat_site_order\": 645}, {\"site\": 648, \"wildtype\": \"I\", \"_stat_site_order\": 646}, {\"site\": 649, \"wildtype\": \"G\", \"_stat_site_order\": 647}, {\"site\": 650, \"wildtype\": \"A\", \"_stat_site_order\": 648}, {\"site\": 651, \"wildtype\": \"E\", \"_stat_site_order\": 649}, {\"site\": 652, \"wildtype\": \"Y\", \"_stat_site_order\": 650}, {\"site\": 653, \"wildtype\": \"V\", \"_stat_site_order\": 651}, {\"site\": 654, \"wildtype\": \"N\", \"_stat_site_order\": 652}, {\"site\": 655, \"wildtype\": \"N\", \"_stat_site_order\": 653}, {\"site\": 656, \"wildtype\": \"S\", \"_stat_site_order\": 654}, {\"site\": 657, \"wildtype\": \"Y\", \"_stat_site_order\": 655}, {\"site\": 658, \"wildtype\": \"E\", \"_stat_site_order\": 656}, {\"site\": 659, \"wildtype\": \"C\", \"_stat_site_order\": 657}, {\"site\": 660, \"wildtype\": \"D\", \"_stat_site_order\": 658}, {\"site\": 661, \"wildtype\": \"I\", \"_stat_site_order\": 659}, {\"site\": 662, \"wildtype\": \"P\", \"_stat_site_order\": 660}, {\"site\": 663, \"wildtype\": \"I\", \"_stat_site_order\": 661}, {\"site\": 664, \"wildtype\": \"G\", \"_stat_site_order\": 662}, {\"site\": 665, \"wildtype\": \"A\", \"_stat_site_order\": 663}, {\"site\": 666, \"wildtype\": \"G\", \"_stat_site_order\": 664}, {\"site\": 667, \"wildtype\": \"I\", \"_stat_site_order\": 665}, {\"site\": 668, \"wildtype\": \"C\", \"_stat_site_order\": 666}, {\"site\": 669, \"wildtype\": \"A\", \"_stat_site_order\": 667}, {\"site\": 670, \"wildtype\": \"S\", \"_stat_site_order\": 668}, {\"site\": 671, \"wildtype\": \"Y\", \"_stat_site_order\": 669}, {\"site\": 672, \"wildtype\": \"Q\", \"_stat_site_order\": 670}, {\"site\": 673, \"wildtype\": \"T\", \"_stat_site_order\": 671}, {\"site\": 674, \"wildtype\": \"Q\", \"_stat_site_order\": 672}, {\"site\": 675, \"wildtype\": \"T\", \"_stat_site_order\": 673}, {\"site\": 676, \"wildtype\": \"K\", \"_stat_site_order\": 674}, {\"site\": 677, \"wildtype\": \"S\", \"_stat_site_order\": 675}, {\"site\": 678, \"wildtype\": \"H\", \"_stat_site_order\": 676}, {\"site\": 679, \"wildtype\": \"R\", \"_stat_site_order\": 677}, {\"site\": 680, \"wildtype\": \"R\", \"_stat_site_order\": 678}, {\"site\": 681, \"wildtype\": \"A\", \"_stat_site_order\": 679}, {\"site\": 682, \"wildtype\": \"R\", \"_stat_site_order\": 680}, {\"site\": 683, \"wildtype\": \"S\", \"_stat_site_order\": 681}, {\"site\": 684, \"wildtype\": \"V\", \"_stat_site_order\": 682}, {\"site\": 685, \"wildtype\": \"A\", \"_stat_site_order\": 683}, {\"site\": 686, \"wildtype\": \"S\", \"_stat_site_order\": 684}, {\"site\": 687, \"wildtype\": \"Q\", \"_stat_site_order\": 685}, {\"site\": 688, \"wildtype\": \"S\", \"_stat_site_order\": 686}, {\"site\": 689, \"wildtype\": \"I\", \"_stat_site_order\": 687}, {\"site\": 690, \"wildtype\": \"I\", \"_stat_site_order\": 688}, {\"site\": 691, \"wildtype\": \"A\", \"_stat_site_order\": 689}, {\"site\": 693, \"wildtype\": \"T\", \"_stat_site_order\": 690}, {\"site\": 694, \"wildtype\": \"M\", \"_stat_site_order\": 691}, {\"site\": 695, \"wildtype\": \"S\", \"_stat_site_order\": 692}, {\"site\": 696, \"wildtype\": \"L\", \"_stat_site_order\": 693}, {\"site\": 697, \"wildtype\": \"G\", \"_stat_site_order\": 694}, {\"site\": 698, \"wildtype\": \"A\", \"_stat_site_order\": 695}, {\"site\": 699, \"wildtype\": \"E\", \"_stat_site_order\": 696}, {\"site\": 700, \"wildtype\": \"N\", \"_stat_site_order\": 697}, {\"site\": 701, \"wildtype\": \"S\", \"_stat_site_order\": 698}, {\"site\": 702, \"wildtype\": \"V\", \"_stat_site_order\": 699}, {\"site\": 703, \"wildtype\": \"A\", \"_stat_site_order\": 700}, {\"site\": 704, \"wildtype\": \"Y\", \"_stat_site_order\": 701}, {\"site\": 705, \"wildtype\": \"S\", \"_stat_site_order\": 702}, {\"site\": 706, \"wildtype\": \"N\", \"_stat_site_order\": 703}, {\"site\": 707, \"wildtype\": \"N\", \"_stat_site_order\": 704}, {\"site\": 708, \"wildtype\": \"S\", \"_stat_site_order\": 705}, {\"site\": 709, \"wildtype\": \"I\", \"_stat_site_order\": 706}, {\"site\": 710, \"wildtype\": \"A\", \"_stat_site_order\": 707}, {\"site\": 711, \"wildtype\": \"I\", \"_stat_site_order\": 708}, {\"site\": 712, \"wildtype\": \"P\", \"_stat_site_order\": 709}, {\"site\": 713, \"wildtype\": \"T\", \"_stat_site_order\": 710}, {\"site\": 714, \"wildtype\": \"N\", \"_stat_site_order\": 711}, {\"site\": 715, \"wildtype\": \"F\", \"_stat_site_order\": 712}, {\"site\": 716, \"wildtype\": \"T\", \"_stat_site_order\": 713}, {\"site\": 717, \"wildtype\": \"I\", \"_stat_site_order\": 714}, {\"site\": 718, \"wildtype\": \"S\", \"_stat_site_order\": 715}, {\"site\": 719, \"wildtype\": \"V\", \"_stat_site_order\": 716}, {\"site\": 720, \"wildtype\": \"T\", \"_stat_site_order\": 717}, {\"site\": 721, \"wildtype\": \"T\", \"_stat_site_order\": 718}, {\"site\": 722, \"wildtype\": \"E\", \"_stat_site_order\": 719}, {\"site\": 723, \"wildtype\": \"I\", \"_stat_site_order\": 720}, {\"site\": 724, \"wildtype\": \"L\", \"_stat_site_order\": 721}, {\"site\": 725, \"wildtype\": \"P\", \"_stat_site_order\": 722}, {\"site\": 726, \"wildtype\": \"V\", \"_stat_site_order\": 723}, {\"site\": 727, \"wildtype\": \"S\", \"_stat_site_order\": 724}, {\"site\": 728, \"wildtype\": \"M\", \"_stat_site_order\": 725}, {\"site\": 729, \"wildtype\": \"T\", \"_stat_site_order\": 726}, {\"site\": 730, \"wildtype\": \"K\", \"_stat_site_order\": 727}, {\"site\": 731, \"wildtype\": \"T\", \"_stat_site_order\": 728}, {\"site\": 732, \"wildtype\": \"S\", \"_stat_site_order\": 729}, {\"site\": 733, \"wildtype\": \"V\", \"_stat_site_order\": 730}, {\"site\": 734, \"wildtype\": \"D\", \"_stat_site_order\": 731}, {\"site\": 735, \"wildtype\": \"C\", \"_stat_site_order\": 732}, {\"site\": 736, \"wildtype\": \"T\", \"_stat_site_order\": 733}, {\"site\": 737, \"wildtype\": \"M\", \"_stat_site_order\": 734}, {\"site\": 738, \"wildtype\": \"Y\", \"_stat_site_order\": 735}, {\"site\": 739, \"wildtype\": \"I\", \"_stat_site_order\": 736}, {\"site\": 740, \"wildtype\": \"C\", \"_stat_site_order\": 737}, {\"site\": 741, \"wildtype\": \"G\", \"_stat_site_order\": 738}, {\"site\": 742, \"wildtype\": \"D\", \"_stat_site_order\": 739}, {\"site\": 743, \"wildtype\": \"S\", \"_stat_site_order\": 740}, {\"site\": 744, \"wildtype\": \"T\", \"_stat_site_order\": 741}, {\"site\": 745, \"wildtype\": \"E\", \"_stat_site_order\": 742}, {\"site\": 746, \"wildtype\": \"C\", \"_stat_site_order\": 743}, {\"site\": 747, \"wildtype\": \"S\", \"_stat_site_order\": 744}, {\"site\": 748, \"wildtype\": \"N\", \"_stat_site_order\": 745}, {\"site\": 749, \"wildtype\": \"L\", \"_stat_site_order\": 746}, {\"site\": 750, \"wildtype\": \"L\", \"_stat_site_order\": 747}, {\"site\": 751, \"wildtype\": \"L\", \"_stat_site_order\": 748}, {\"site\": 752, \"wildtype\": \"Q\", \"_stat_site_order\": 749}, {\"site\": 753, \"wildtype\": \"Y\", \"_stat_site_order\": 750}, {\"site\": 754, \"wildtype\": \"G\", \"_stat_site_order\": 751}, {\"site\": 755, \"wildtype\": \"S\", \"_stat_site_order\": 752}, {\"site\": 756, \"wildtype\": \"F\", \"_stat_site_order\": 753}, {\"site\": 757, \"wildtype\": \"C\", \"_stat_site_order\": 754}, {\"site\": 758, \"wildtype\": \"T\", \"_stat_site_order\": 755}, {\"site\": 759, \"wildtype\": \"Q\", \"_stat_site_order\": 756}, {\"site\": 760, \"wildtype\": \"L\", \"_stat_site_order\": 757}, {\"site\": 761, \"wildtype\": \"K\", \"_stat_site_order\": 758}, {\"site\": 762, \"wildtype\": \"R\", \"_stat_site_order\": 759}, {\"site\": 763, \"wildtype\": \"A\", \"_stat_site_order\": 760}, {\"site\": 764, \"wildtype\": \"L\", \"_stat_site_order\": 761}, {\"site\": 765, \"wildtype\": \"T\", \"_stat_site_order\": 762}, {\"site\": 766, \"wildtype\": \"G\", \"_stat_site_order\": 763}, {\"site\": 767, \"wildtype\": \"I\", \"_stat_site_order\": 764}, {\"site\": 768, \"wildtype\": \"A\", \"_stat_site_order\": 765}, {\"site\": 769, \"wildtype\": \"V\", \"_stat_site_order\": 766}, {\"site\": 770, \"wildtype\": \"E\", \"_stat_site_order\": 767}, {\"site\": 771, \"wildtype\": \"Q\", \"_stat_site_order\": 768}, {\"site\": 772, \"wildtype\": \"D\", \"_stat_site_order\": 769}, {\"site\": 773, \"wildtype\": \"K\", \"_stat_site_order\": 770}, {\"site\": 774, \"wildtype\": \"N\", \"_stat_site_order\": 771}, {\"site\": 775, \"wildtype\": \"T\", \"_stat_site_order\": 772}, {\"site\": 776, \"wildtype\": \"Q\", \"_stat_site_order\": 773}, {\"site\": 777, \"wildtype\": \"E\", \"_stat_site_order\": 774}, {\"site\": 778, \"wildtype\": \"V\", \"_stat_site_order\": 775}, {\"site\": 779, \"wildtype\": \"F\", \"_stat_site_order\": 776}, {\"site\": 780, \"wildtype\": \"A\", \"_stat_site_order\": 777}, {\"site\": 781, \"wildtype\": \"Q\", \"_stat_site_order\": 778}, {\"site\": 782, \"wildtype\": \"V\", \"_stat_site_order\": 779}, {\"site\": 783, \"wildtype\": \"K\", \"_stat_site_order\": 780}, {\"site\": 784, \"wildtype\": \"Q\", \"_stat_site_order\": 781}, {\"site\": 785, \"wildtype\": \"I\", \"_stat_site_order\": 782}, {\"site\": 786, \"wildtype\": \"Y\", \"_stat_site_order\": 783}, {\"site\": 787, \"wildtype\": \"K\", \"_stat_site_order\": 784}, {\"site\": 788, \"wildtype\": \"T\", \"_stat_site_order\": 785}, {\"site\": 789, \"wildtype\": \"P\", \"_stat_site_order\": 786}, {\"site\": 790, \"wildtype\": \"P\", \"_stat_site_order\": 787}, {\"site\": 791, \"wildtype\": \"I\", \"_stat_site_order\": 788}, {\"site\": 792, \"wildtype\": \"K\", \"_stat_site_order\": 789}, {\"site\": 793, \"wildtype\": \"Y\", \"_stat_site_order\": 790}, {\"site\": 794, \"wildtype\": \"F\", \"_stat_site_order\": 791}, {\"site\": 795, \"wildtype\": \"G\", \"_stat_site_order\": 792}, {\"site\": 796, \"wildtype\": \"G\", \"_stat_site_order\": 793}, {\"site\": 797, \"wildtype\": \"F\", \"_stat_site_order\": 794}, {\"site\": 798, \"wildtype\": \"N\", \"_stat_site_order\": 795}, {\"site\": 799, \"wildtype\": \"F\", \"_stat_site_order\": 796}, {\"site\": 800, \"wildtype\": \"S\", \"_stat_site_order\": 797}, {\"site\": 801, \"wildtype\": \"Q\", \"_stat_site_order\": 798}, {\"site\": 802, \"wildtype\": \"I\", \"_stat_site_order\": 799}, {\"site\": 803, \"wildtype\": \"L\", \"_stat_site_order\": 800}, {\"site\": 804, \"wildtype\": \"P\", \"_stat_site_order\": 801}, {\"site\": 805, \"wildtype\": \"D\", \"_stat_site_order\": 802}, {\"site\": 806, \"wildtype\": \"P\", \"_stat_site_order\": 803}, {\"site\": 807, \"wildtype\": \"S\", \"_stat_site_order\": 804}, {\"site\": 808, \"wildtype\": \"K\", \"_stat_site_order\": 805}, {\"site\": 809, \"wildtype\": \"P\", \"_stat_site_order\": 806}, {\"site\": 810, \"wildtype\": \"S\", \"_stat_site_order\": 807}, {\"site\": 811, \"wildtype\": \"K\", \"_stat_site_order\": 808}, {\"site\": 812, \"wildtype\": \"R\", \"_stat_site_order\": 809}, {\"site\": 813, \"wildtype\": \"S\", \"_stat_site_order\": 810}, {\"site\": 814, \"wildtype\": \"F\", \"_stat_site_order\": 811}, {\"site\": 815, \"wildtype\": \"I\", \"_stat_site_order\": 812}, {\"site\": 816, \"wildtype\": \"E\", \"_stat_site_order\": 813}, {\"site\": 817, \"wildtype\": \"D\", \"_stat_site_order\": 814}, {\"site\": 818, \"wildtype\": \"L\", \"_stat_site_order\": 815}, {\"site\": 819, \"wildtype\": \"L\", \"_stat_site_order\": 816}, {\"site\": 820, \"wildtype\": \"F\", \"_stat_site_order\": 817}, {\"site\": 821, \"wildtype\": \"N\", \"_stat_site_order\": 818}, {\"site\": 822, \"wildtype\": \"K\", \"_stat_site_order\": 819}, {\"site\": 823, \"wildtype\": \"V\", \"_stat_site_order\": 820}, {\"site\": 824, \"wildtype\": \"T\", \"_stat_site_order\": 821}, {\"site\": 825, \"wildtype\": \"L\", \"_stat_site_order\": 822}, {\"site\": 826, \"wildtype\": \"A\", \"_stat_site_order\": 823}, {\"site\": 827, \"wildtype\": \"D\", \"_stat_site_order\": 824}, {\"site\": 828, \"wildtype\": \"A\", \"_stat_site_order\": 825}, {\"site\": 829, \"wildtype\": \"G\", \"_stat_site_order\": 826}, {\"site\": 830, \"wildtype\": \"F\", \"_stat_site_order\": 827}, {\"site\": 831, \"wildtype\": \"I\", \"_stat_site_order\": 828}, {\"site\": 832, \"wildtype\": \"K\", \"_stat_site_order\": 829}, {\"site\": 833, \"wildtype\": \"Q\", \"_stat_site_order\": 830}, {\"site\": 834, \"wildtype\": \"Y\", \"_stat_site_order\": 831}, {\"site\": 835, \"wildtype\": \"G\", \"_stat_site_order\": 832}, {\"site\": 836, \"wildtype\": \"D\", \"_stat_site_order\": 833}, {\"site\": 837, \"wildtype\": \"C\", \"_stat_site_order\": 834}, {\"site\": 838, \"wildtype\": \"L\", \"_stat_site_order\": 835}, {\"site\": 839, \"wildtype\": \"G\", \"_stat_site_order\": 836}, {\"site\": 840, \"wildtype\": \"D\", \"_stat_site_order\": 837}, {\"site\": 841, \"wildtype\": \"I\", \"_stat_site_order\": 838}, {\"site\": 842, \"wildtype\": \"A\", \"_stat_site_order\": 839}, {\"site\": 843, \"wildtype\": \"A\", \"_stat_site_order\": 840}, {\"site\": 844, \"wildtype\": \"R\", \"_stat_site_order\": 841}, {\"site\": 845, \"wildtype\": \"D\", \"_stat_site_order\": 842}, {\"site\": 846, \"wildtype\": \"L\", \"_stat_site_order\": 843}, {\"site\": 847, \"wildtype\": \"I\", \"_stat_site_order\": 844}, {\"site\": 848, \"wildtype\": \"C\", \"_stat_site_order\": 845}, {\"site\": 849, \"wildtype\": \"A\", \"_stat_site_order\": 846}, {\"site\": 850, \"wildtype\": \"Q\", \"_stat_site_order\": 847}, {\"site\": 851, \"wildtype\": \"K\", \"_stat_site_order\": 848}, {\"site\": 852, \"wildtype\": \"F\", \"_stat_site_order\": 849}, {\"site\": 853, \"wildtype\": \"K\", \"_stat_site_order\": 850}, {\"site\": 854, \"wildtype\": \"G\", \"_stat_site_order\": 851}, {\"site\": 855, \"wildtype\": \"L\", \"_stat_site_order\": 852}, {\"site\": 856, \"wildtype\": \"T\", \"_stat_site_order\": 853}, {\"site\": 857, \"wildtype\": \"V\", \"_stat_site_order\": 854}, {\"site\": 858, \"wildtype\": \"L\", \"_stat_site_order\": 855}, {\"site\": 859, \"wildtype\": \"P\", \"_stat_site_order\": 856}, {\"site\": 860, \"wildtype\": \"P\", \"_stat_site_order\": 857}, {\"site\": 861, \"wildtype\": \"L\", \"_stat_site_order\": 858}, {\"site\": 862, \"wildtype\": \"L\", \"_stat_site_order\": 859}, {\"site\": 863, \"wildtype\": \"T\", \"_stat_site_order\": 860}, {\"site\": 864, \"wildtype\": \"D\", \"_stat_site_order\": 861}, {\"site\": 865, \"wildtype\": \"E\", \"_stat_site_order\": 862}, {\"site\": 866, \"wildtype\": \"M\", \"_stat_site_order\": 863}, {\"site\": 867, \"wildtype\": \"I\", \"_stat_site_order\": 864}, {\"site\": 868, \"wildtype\": \"A\", \"_stat_site_order\": 865}, {\"site\": 869, \"wildtype\": \"Q\", \"_stat_site_order\": 866}, {\"site\": 870, \"wildtype\": \"Y\", \"_stat_site_order\": 867}, {\"site\": 871, \"wildtype\": \"T\", \"_stat_site_order\": 868}, {\"site\": 872, \"wildtype\": \"S\", \"_stat_site_order\": 869}, {\"site\": 873, \"wildtype\": \"A\", \"_stat_site_order\": 870}, {\"site\": 874, \"wildtype\": \"L\", \"_stat_site_order\": 871}, {\"site\": 875, \"wildtype\": \"L\", \"_stat_site_order\": 872}, {\"site\": 876, \"wildtype\": \"A\", \"_stat_site_order\": 873}, {\"site\": 877, \"wildtype\": \"G\", \"_stat_site_order\": 874}, {\"site\": 878, \"wildtype\": \"T\", \"_stat_site_order\": 875}, {\"site\": 879, \"wildtype\": \"I\", \"_stat_site_order\": 876}, {\"site\": 880, \"wildtype\": \"T\", \"_stat_site_order\": 877}, {\"site\": 881, \"wildtype\": \"S\", \"_stat_site_order\": 878}, {\"site\": 882, \"wildtype\": \"G\", \"_stat_site_order\": 879}, {\"site\": 883, \"wildtype\": \"W\", \"_stat_site_order\": 880}, {\"site\": 884, \"wildtype\": \"T\", \"_stat_site_order\": 881}, {\"site\": 885, \"wildtype\": \"F\", \"_stat_site_order\": 882}, {\"site\": 886, \"wildtype\": \"G\", \"_stat_site_order\": 883}, {\"site\": 887, \"wildtype\": \"A\", \"_stat_site_order\": 884}, {\"site\": 888, \"wildtype\": \"G\", \"_stat_site_order\": 885}, {\"site\": 889, \"wildtype\": \"A\", \"_stat_site_order\": 886}, {\"site\": 890, \"wildtype\": \"A\", \"_stat_site_order\": 887}, {\"site\": 891, \"wildtype\": \"L\", \"_stat_site_order\": 888}, {\"site\": 892, \"wildtype\": \"Q\", \"_stat_site_order\": 889}, {\"site\": 893, \"wildtype\": \"I\", \"_stat_site_order\": 890}, {\"site\": 894, \"wildtype\": \"P\", \"_stat_site_order\": 891}, {\"site\": 895, \"wildtype\": \"F\", \"_stat_site_order\": 892}, {\"site\": 896, \"wildtype\": \"A\", \"_stat_site_order\": 893}, {\"site\": 897, \"wildtype\": \"M\", \"_stat_site_order\": 894}, {\"site\": 898, \"wildtype\": \"Q\", \"_stat_site_order\": 895}, {\"site\": 899, \"wildtype\": \"M\", \"_stat_site_order\": 896}, {\"site\": 900, \"wildtype\": \"A\", \"_stat_site_order\": 897}, {\"site\": 901, \"wildtype\": \"Y\", \"_stat_site_order\": 898}, {\"site\": 902, \"wildtype\": \"R\", \"_stat_site_order\": 899}, {\"site\": 903, \"wildtype\": \"F\", \"_stat_site_order\": 900}, {\"site\": 904, \"wildtype\": \"N\", \"_stat_site_order\": 901}, {\"site\": 905, \"wildtype\": \"G\", \"_stat_site_order\": 902}, {\"site\": 906, \"wildtype\": \"I\", \"_stat_site_order\": 903}, {\"site\": 907, \"wildtype\": \"G\", \"_stat_site_order\": 904}, {\"site\": 908, \"wildtype\": \"V\", \"_stat_site_order\": 905}, {\"site\": 909, \"wildtype\": \"T\", \"_stat_site_order\": 906}, {\"site\": 910, \"wildtype\": \"Q\", \"_stat_site_order\": 907}, {\"site\": 911, \"wildtype\": \"N\", \"_stat_site_order\": 908}, {\"site\": 912, \"wildtype\": \"V\", \"_stat_site_order\": 909}, {\"site\": 913, \"wildtype\": \"L\", \"_stat_site_order\": 910}, {\"site\": 914, \"wildtype\": \"Y\", \"_stat_site_order\": 911}, {\"site\": 915, \"wildtype\": \"E\", \"_stat_site_order\": 912}, {\"site\": 916, \"wildtype\": \"N\", \"_stat_site_order\": 913}, {\"site\": 917, \"wildtype\": \"Q\", \"_stat_site_order\": 914}, {\"site\": 918, \"wildtype\": \"K\", \"_stat_site_order\": 915}, {\"site\": 919, \"wildtype\": \"L\", \"_stat_site_order\": 916}, {\"site\": 920, \"wildtype\": \"I\", \"_stat_site_order\": 917}, {\"site\": 921, \"wildtype\": \"A\", \"_stat_site_order\": 918}, {\"site\": 922, \"wildtype\": \"N\", \"_stat_site_order\": 919}, {\"site\": 923, \"wildtype\": \"Q\", \"_stat_site_order\": 920}, {\"site\": 924, \"wildtype\": \"F\", \"_stat_site_order\": 921}, {\"site\": 925, \"wildtype\": \"N\", \"_stat_site_order\": 922}, {\"site\": 926, \"wildtype\": \"S\", \"_stat_site_order\": 923}, {\"site\": 927, \"wildtype\": \"A\", \"_stat_site_order\": 924}, {\"site\": 928, \"wildtype\": \"I\", \"_stat_site_order\": 925}, {\"site\": 929, \"wildtype\": \"G\", \"_stat_site_order\": 926}, {\"site\": 930, \"wildtype\": \"K\", \"_stat_site_order\": 927}, {\"site\": 931, \"wildtype\": \"I\", \"_stat_site_order\": 928}, {\"site\": 932, \"wildtype\": \"Q\", \"_stat_site_order\": 929}, {\"site\": 933, \"wildtype\": \"D\", \"_stat_site_order\": 930}, {\"site\": 934, \"wildtype\": \"S\", \"_stat_site_order\": 931}, {\"site\": 935, \"wildtype\": \"L\", \"_stat_site_order\": 932}, {\"site\": 936, \"wildtype\": \"S\", \"_stat_site_order\": 933}, {\"site\": 937, \"wildtype\": \"S\", \"_stat_site_order\": 934}, {\"site\": 938, \"wildtype\": \"T\", \"_stat_site_order\": 935}, {\"site\": 939, \"wildtype\": \"A\", \"_stat_site_order\": 936}, {\"site\": 940, \"wildtype\": \"S\", \"_stat_site_order\": 937}, {\"site\": 941, \"wildtype\": \"A\", \"_stat_site_order\": 938}, {\"site\": 942, \"wildtype\": \"L\", \"_stat_site_order\": 939}, {\"site\": 943, \"wildtype\": \"G\", \"_stat_site_order\": 940}, {\"site\": 944, \"wildtype\": \"K\", \"_stat_site_order\": 941}, {\"site\": 945, \"wildtype\": \"L\", \"_stat_site_order\": 942}, {\"site\": 946, \"wildtype\": \"Q\", \"_stat_site_order\": 943}, {\"site\": 947, \"wildtype\": \"D\", \"_stat_site_order\": 944}, {\"site\": 948, \"wildtype\": \"V\", \"_stat_site_order\": 945}, {\"site\": 949, \"wildtype\": \"V\", \"_stat_site_order\": 946}, {\"site\": 950, \"wildtype\": \"N\", \"_stat_site_order\": 947}, {\"site\": 951, \"wildtype\": \"H\", \"_stat_site_order\": 948}, {\"site\": 952, \"wildtype\": \"N\", \"_stat_site_order\": 949}, {\"site\": 953, \"wildtype\": \"A\", \"_stat_site_order\": 950}, {\"site\": 954, \"wildtype\": \"Q\", \"_stat_site_order\": 951}, {\"site\": 955, \"wildtype\": \"A\", \"_stat_site_order\": 952}, {\"site\": 956, \"wildtype\": \"L\", \"_stat_site_order\": 953}, {\"site\": 957, \"wildtype\": \"N\", \"_stat_site_order\": 954}, {\"site\": 958, \"wildtype\": \"T\", \"_stat_site_order\": 955}, {\"site\": 959, \"wildtype\": \"L\", \"_stat_site_order\": 956}, {\"site\": 960, \"wildtype\": \"V\", \"_stat_site_order\": 957}, {\"site\": 961, \"wildtype\": \"K\", \"_stat_site_order\": 958}, {\"site\": 962, \"wildtype\": \"Q\", \"_stat_site_order\": 959}, {\"site\": 963, \"wildtype\": \"L\", \"_stat_site_order\": 960}, {\"site\": 964, \"wildtype\": \"S\", \"_stat_site_order\": 961}, {\"site\": 965, \"wildtype\": \"S\", \"_stat_site_order\": 962}, {\"site\": 966, \"wildtype\": \"K\", \"_stat_site_order\": 963}, {\"site\": 967, \"wildtype\": \"F\", \"_stat_site_order\": 964}, {\"site\": 968, \"wildtype\": \"G\", \"_stat_site_order\": 965}, {\"site\": 969, \"wildtype\": \"A\", \"_stat_site_order\": 966}, {\"site\": 970, \"wildtype\": \"I\", \"_stat_site_order\": 967}, {\"site\": 971, \"wildtype\": \"S\", \"_stat_site_order\": 968}, {\"site\": 972, \"wildtype\": \"S\", \"_stat_site_order\": 969}, {\"site\": 973, \"wildtype\": \"V\", \"_stat_site_order\": 970}, {\"site\": 974, \"wildtype\": \"L\", \"_stat_site_order\": 971}, {\"site\": 975, \"wildtype\": \"N\", \"_stat_site_order\": 972}, {\"site\": 976, \"wildtype\": \"D\", \"_stat_site_order\": 973}, {\"site\": 977, \"wildtype\": \"I\", \"_stat_site_order\": 974}, {\"site\": 978, \"wildtype\": \"F\", \"_stat_site_order\": 975}, {\"site\": 979, \"wildtype\": \"S\", \"_stat_site_order\": 976}, {\"site\": 980, \"wildtype\": \"R\", \"_stat_site_order\": 977}, {\"site\": 981, \"wildtype\": \"L\", \"_stat_site_order\": 978}, {\"site\": 982, \"wildtype\": \"D\", \"_stat_site_order\": 979}, {\"site\": 983, \"wildtype\": \"K\", \"_stat_site_order\": 980}, {\"site\": 984, \"wildtype\": \"V\", \"_stat_site_order\": 981}, {\"site\": 985, \"wildtype\": \"E\", \"_stat_site_order\": 982}, {\"site\": 986, \"wildtype\": \"A\", \"_stat_site_order\": 983}, {\"site\": 987, \"wildtype\": \"E\", \"_stat_site_order\": 984}, {\"site\": 988, \"wildtype\": \"V\", \"_stat_site_order\": 985}, {\"site\": 989, \"wildtype\": \"Q\", \"_stat_site_order\": 986}, {\"site\": 990, \"wildtype\": \"I\", \"_stat_site_order\": 987}, {\"site\": 991, \"wildtype\": \"D\", \"_stat_site_order\": 988}, {\"site\": 992, \"wildtype\": \"R\", \"_stat_site_order\": 989}, {\"site\": 993, \"wildtype\": \"L\", \"_stat_site_order\": 990}, {\"site\": 994, \"wildtype\": \"I\", \"_stat_site_order\": 991}, {\"site\": 995, \"wildtype\": \"T\", \"_stat_site_order\": 992}, {\"site\": 996, \"wildtype\": \"G\", \"_stat_site_order\": 993}, {\"site\": 997, \"wildtype\": \"R\", \"_stat_site_order\": 994}, {\"site\": 998, \"wildtype\": \"L\", \"_stat_site_order\": 995}, {\"site\": 999, \"wildtype\": \"Q\", \"_stat_site_order\": 996}, {\"site\": 1000, \"wildtype\": \"S\", \"_stat_site_order\": 997}, {\"site\": 1001, \"wildtype\": \"L\", \"_stat_site_order\": 998}, {\"site\": 1002, \"wildtype\": \"Q\", \"_stat_site_order\": 999}, {\"site\": 1003, \"wildtype\": \"T\", \"_stat_site_order\": 1000}, {\"site\": 1004, \"wildtype\": \"Y\", \"_stat_site_order\": 1001}, {\"site\": 1005, \"wildtype\": \"V\", \"_stat_site_order\": 1002}, {\"site\": 1006, \"wildtype\": \"T\", \"_stat_site_order\": 1003}, {\"site\": 1007, \"wildtype\": \"Q\", \"_stat_site_order\": 1004}, {\"site\": 1008, \"wildtype\": \"Q\", \"_stat_site_order\": 1005}, {\"site\": 1009, \"wildtype\": \"L\", \"_stat_site_order\": 1006}, {\"site\": 1010, \"wildtype\": \"I\", \"_stat_site_order\": 1007}, {\"site\": 1011, \"wildtype\": \"R\", \"_stat_site_order\": 1008}, {\"site\": 1012, \"wildtype\": \"A\", \"_stat_site_order\": 1009}, {\"site\": 1013, \"wildtype\": \"A\", \"_stat_site_order\": 1010}, {\"site\": 1014, \"wildtype\": \"E\", \"_stat_site_order\": 1011}, {\"site\": 1015, \"wildtype\": \"I\", \"_stat_site_order\": 1012}, {\"site\": 1016, \"wildtype\": \"R\", \"_stat_site_order\": 1013}, {\"site\": 1017, \"wildtype\": \"A\", \"_stat_site_order\": 1014}, {\"site\": 1018, \"wildtype\": \"S\", \"_stat_site_order\": 1015}, {\"site\": 1019, \"wildtype\": \"A\", \"_stat_site_order\": 1016}, {\"site\": 1020, \"wildtype\": \"N\", \"_stat_site_order\": 1017}, {\"site\": 1021, \"wildtype\": \"L\", \"_stat_site_order\": 1018}, {\"site\": 1022, \"wildtype\": \"A\", \"_stat_site_order\": 1019}, {\"site\": 1023, \"wildtype\": \"A\", \"_stat_site_order\": 1020}, {\"site\": 1024, \"wildtype\": \"T\", \"_stat_site_order\": 1021}, {\"site\": 1025, \"wildtype\": \"K\", \"_stat_site_order\": 1022}, {\"site\": 1026, \"wildtype\": \"M\", \"_stat_site_order\": 1023}, {\"site\": 1027, \"wildtype\": \"S\", \"_stat_site_order\": 1024}, {\"site\": 1028, \"wildtype\": \"E\", \"_stat_site_order\": 1025}, {\"site\": 1029, \"wildtype\": \"C\", \"_stat_site_order\": 1026}, {\"site\": 1030, \"wildtype\": \"V\", \"_stat_site_order\": 1027}, {\"site\": 1031, \"wildtype\": \"L\", \"_stat_site_order\": 1028}, {\"site\": 1032, \"wildtype\": \"G\", \"_stat_site_order\": 1029}, {\"site\": 1033, \"wildtype\": \"Q\", \"_stat_site_order\": 1030}, {\"site\": 1034, \"wildtype\": \"S\", \"_stat_site_order\": 1031}, {\"site\": 1035, \"wildtype\": \"K\", \"_stat_site_order\": 1032}, {\"site\": 1036, \"wildtype\": \"R\", \"_stat_site_order\": 1033}, {\"site\": 1037, \"wildtype\": \"V\", \"_stat_site_order\": 1034}, {\"site\": 1038, \"wildtype\": \"D\", \"_stat_site_order\": 1035}, {\"site\": 1039, \"wildtype\": \"F\", \"_stat_site_order\": 1036}, {\"site\": 1040, \"wildtype\": \"C\", \"_stat_site_order\": 1037}, {\"site\": 1041, \"wildtype\": \"G\", \"_stat_site_order\": 1038}, {\"site\": 1042, \"wildtype\": \"K\", \"_stat_site_order\": 1039}, {\"site\": 1043, \"wildtype\": \"G\", \"_stat_site_order\": 1040}, {\"site\": 1044, \"wildtype\": \"Y\", \"_stat_site_order\": 1041}, {\"site\": 1045, \"wildtype\": \"H\", \"_stat_site_order\": 1042}, {\"site\": 1046, \"wildtype\": \"L\", \"_stat_site_order\": 1043}, {\"site\": 1047, \"wildtype\": \"M\", \"_stat_site_order\": 1044}, {\"site\": 1048, \"wildtype\": \"S\", \"_stat_site_order\": 1045}, {\"site\": 1049, \"wildtype\": \"F\", \"_stat_site_order\": 1046}, {\"site\": 1051, \"wildtype\": \"Q\", \"_stat_site_order\": 1047}, {\"site\": 1052, \"wildtype\": \"S\", \"_stat_site_order\": 1048}, {\"site\": 1053, \"wildtype\": \"A\", \"_stat_site_order\": 1049}, {\"site\": 1054, \"wildtype\": \"P\", \"_stat_site_order\": 1050}, {\"site\": 1055, \"wildtype\": \"H\", \"_stat_site_order\": 1051}, {\"site\": 1056, \"wildtype\": \"G\", \"_stat_site_order\": 1052}, {\"site\": 1057, \"wildtype\": \"V\", \"_stat_site_order\": 1053}, {\"site\": 1058, \"wildtype\": \"V\", \"_stat_site_order\": 1054}, {\"site\": 1059, \"wildtype\": \"F\", \"_stat_site_order\": 1055}, {\"site\": 1060, \"wildtype\": \"L\", \"_stat_site_order\": 1056}, {\"site\": 1061, \"wildtype\": \"H\", \"_stat_site_order\": 1057}, {\"site\": 1062, \"wildtype\": \"V\", \"_stat_site_order\": 1058}, {\"site\": 1063, \"wildtype\": \"T\", \"_stat_site_order\": 1059}, {\"site\": 1064, \"wildtype\": \"Y\", \"_stat_site_order\": 1060}, {\"site\": 1065, \"wildtype\": \"V\", \"_stat_site_order\": 1061}, {\"site\": 1066, \"wildtype\": \"P\", \"_stat_site_order\": 1062}, {\"site\": 1067, \"wildtype\": \"A\", \"_stat_site_order\": 1063}, {\"site\": 1068, \"wildtype\": \"Q\", \"_stat_site_order\": 1064}, {\"site\": 1069, \"wildtype\": \"E\", \"_stat_site_order\": 1065}, {\"site\": 1070, \"wildtype\": \"K\", \"_stat_site_order\": 1066}, {\"site\": 1071, \"wildtype\": \"N\", \"_stat_site_order\": 1067}, {\"site\": 1072, \"wildtype\": \"F\", \"_stat_site_order\": 1068}, {\"site\": 1073, \"wildtype\": \"T\", \"_stat_site_order\": 1069}, {\"site\": 1074, \"wildtype\": \"T\", \"_stat_site_order\": 1070}, {\"site\": 1075, \"wildtype\": \"A\", \"_stat_site_order\": 1071}, {\"site\": 1076, \"wildtype\": \"P\", \"_stat_site_order\": 1072}, {\"site\": 1077, \"wildtype\": \"A\", \"_stat_site_order\": 1073}, {\"site\": 1078, \"wildtype\": \"I\", \"_stat_site_order\": 1074}, {\"site\": 1079, \"wildtype\": \"C\", \"_stat_site_order\": 1075}, {\"site\": 1080, \"wildtype\": \"H\", \"_stat_site_order\": 1076}, {\"site\": 1081, \"wildtype\": \"D\", \"_stat_site_order\": 1077}, {\"site\": 1082, \"wildtype\": \"G\", \"_stat_site_order\": 1078}, {\"site\": 1083, \"wildtype\": \"K\", \"_stat_site_order\": 1079}, {\"site\": 1084, \"wildtype\": \"A\", \"_stat_site_order\": 1080}, {\"site\": 1085, \"wildtype\": \"H\", \"_stat_site_order\": 1081}, {\"site\": 1086, \"wildtype\": \"F\", \"_stat_site_order\": 1082}, {\"site\": 1087, \"wildtype\": \"P\", \"_stat_site_order\": 1083}, {\"site\": 1088, \"wildtype\": \"R\", \"_stat_site_order\": 1084}, {\"site\": 1089, \"wildtype\": \"E\", \"_stat_site_order\": 1085}, {\"site\": 1090, \"wildtype\": \"G\", \"_stat_site_order\": 1086}, {\"site\": 1091, \"wildtype\": \"V\", \"_stat_site_order\": 1087}, {\"site\": 1092, \"wildtype\": \"F\", \"_stat_site_order\": 1088}, {\"site\": 1093, \"wildtype\": \"V\", \"_stat_site_order\": 1089}, {\"site\": 1094, \"wildtype\": \"S\", \"_stat_site_order\": 1090}, {\"site\": 1095, \"wildtype\": \"N\", \"_stat_site_order\": 1091}, {\"site\": 1096, \"wildtype\": \"G\", \"_stat_site_order\": 1092}, {\"site\": 1097, \"wildtype\": \"T\", \"_stat_site_order\": 1093}, {\"site\": 1098, \"wildtype\": \"H\", \"_stat_site_order\": 1094}, {\"site\": 1099, \"wildtype\": \"W\", \"_stat_site_order\": 1095}, {\"site\": 1100, \"wildtype\": \"F\", \"_stat_site_order\": 1096}, {\"site\": 1101, \"wildtype\": \"V\", \"_stat_site_order\": 1097}, {\"site\": 1102, \"wildtype\": \"T\", \"_stat_site_order\": 1098}, {\"site\": 1103, \"wildtype\": \"Q\", \"_stat_site_order\": 1099}, {\"site\": 1104, \"wildtype\": \"R\", \"_stat_site_order\": 1100}, {\"site\": 1105, \"wildtype\": \"N\", \"_stat_site_order\": 1101}, {\"site\": 1106, \"wildtype\": \"F\", \"_stat_site_order\": 1102}, {\"site\": 1107, \"wildtype\": \"Y\", \"_stat_site_order\": 1103}, {\"site\": 1108, \"wildtype\": \"E\", \"_stat_site_order\": 1104}, {\"site\": 1109, \"wildtype\": \"P\", \"_stat_site_order\": 1105}, {\"site\": 1110, \"wildtype\": \"Q\", \"_stat_site_order\": 1106}, {\"site\": 1111, \"wildtype\": \"I\", \"_stat_site_order\": 1107}, {\"site\": 1112, \"wildtype\": \"I\", \"_stat_site_order\": 1108}, {\"site\": 1113, \"wildtype\": \"T\", \"_stat_site_order\": 1109}, {\"site\": 1114, \"wildtype\": \"T\", \"_stat_site_order\": 1110}, {\"site\": 1115, \"wildtype\": \"D\", \"_stat_site_order\": 1111}, {\"site\": 1116, \"wildtype\": \"N\", \"_stat_site_order\": 1112}, {\"site\": 1117, \"wildtype\": \"T\", \"_stat_site_order\": 1113}, {\"site\": 1118, \"wildtype\": \"F\", \"_stat_site_order\": 1114}, {\"site\": 1119, \"wildtype\": \"V\", \"_stat_site_order\": 1115}, {\"site\": 1120, \"wildtype\": \"S\", \"_stat_site_order\": 1116}, {\"site\": 1121, \"wildtype\": \"G\", \"_stat_site_order\": 1117}, {\"site\": 1122, \"wildtype\": \"N\", \"_stat_site_order\": 1118}, {\"site\": 1123, \"wildtype\": \"C\", \"_stat_site_order\": 1119}, {\"site\": 1124, \"wildtype\": \"D\", \"_stat_site_order\": 1120}, {\"site\": 1125, \"wildtype\": \"V\", \"_stat_site_order\": 1121}, {\"site\": 1126, \"wildtype\": \"V\", \"_stat_site_order\": 1122}, {\"site\": 1127, \"wildtype\": \"I\", \"_stat_site_order\": 1123}, {\"site\": 1128, \"wildtype\": \"G\", \"_stat_site_order\": 1124}, {\"site\": 1129, \"wildtype\": \"I\", \"_stat_site_order\": 1125}, {\"site\": 1130, \"wildtype\": \"V\", \"_stat_site_order\": 1126}, {\"site\": 1131, \"wildtype\": \"N\", \"_stat_site_order\": 1127}, {\"site\": 1132, \"wildtype\": \"N\", \"_stat_site_order\": 1128}, {\"site\": 1133, \"wildtype\": \"T\", \"_stat_site_order\": 1129}, {\"site\": 1134, \"wildtype\": \"V\", \"_stat_site_order\": 1130}, {\"site\": 1135, \"wildtype\": \"Y\", \"_stat_site_order\": 1131}, {\"site\": 1136, \"wildtype\": \"D\", \"_stat_site_order\": 1132}, {\"site\": 1137, \"wildtype\": \"P\", \"_stat_site_order\": 1133}, {\"site\": 1138, \"wildtype\": \"L\", \"_stat_site_order\": 1134}, {\"site\": 1139, \"wildtype\": \"Q\", \"_stat_site_order\": 1135}, {\"site\": 1140, \"wildtype\": \"P\", \"_stat_site_order\": 1136}, {\"site\": 1141, \"wildtype\": \"E\", \"_stat_site_order\": 1137}, {\"site\": 1142, \"wildtype\": \"L\", \"_stat_site_order\": 1138}, {\"site\": 1143, \"wildtype\": \"D\", \"_stat_site_order\": 1139}, {\"site\": 1144, \"wildtype\": \"S\", \"_stat_site_order\": 1140}, {\"site\": 1145, \"wildtype\": \"F\", \"_stat_site_order\": 1141}, {\"site\": 1146, \"wildtype\": \"K\", \"_stat_site_order\": 1142}, {\"site\": 1147, \"wildtype\": \"E\", \"_stat_site_order\": 1143}, {\"site\": 1148, \"wildtype\": \"E\", \"_stat_site_order\": 1144}, {\"site\": 1149, \"wildtype\": \"L\", \"_stat_site_order\": 1145}, {\"site\": 1150, \"wildtype\": \"D\", \"_stat_site_order\": 1146}, {\"site\": 1151, \"wildtype\": \"K\", \"_stat_site_order\": 1147}, {\"site\": 1152, \"wildtype\": \"Y\", \"_stat_site_order\": 1148}, {\"site\": 1153, \"wildtype\": \"F\", \"_stat_site_order\": 1149}, {\"site\": 1154, \"wildtype\": \"K\", \"_stat_site_order\": 1150}, {\"site\": 1155, \"wildtype\": \"N\", \"_stat_site_order\": 1151}, {\"site\": 1156, \"wildtype\": \"H\", \"_stat_site_order\": 1152}, {\"site\": 1157, \"wildtype\": \"T\", \"_stat_site_order\": 1153}, {\"site\": 1158, \"wildtype\": \"S\", \"_stat_site_order\": 1154}, {\"site\": 1159, \"wildtype\": \"P\", \"_stat_site_order\": 1155}, {\"site\": 1160, \"wildtype\": \"D\", \"_stat_site_order\": 1156}, {\"site\": 1161, \"wildtype\": \"V\", \"_stat_site_order\": 1157}, {\"site\": 1162, \"wildtype\": \"D\", \"_stat_site_order\": 1158}, {\"site\": 1163, \"wildtype\": \"L\", \"_stat_site_order\": 1159}, {\"site\": 1164, \"wildtype\": \"G\", \"_stat_site_order\": 1160}, {\"site\": 1165, \"wildtype\": \"D\", \"_stat_site_order\": 1161}, {\"site\": 1166, \"wildtype\": \"I\", \"_stat_site_order\": 1162}, {\"site\": 1167, \"wildtype\": \"S\", \"_stat_site_order\": 1163}, {\"site\": 1168, \"wildtype\": \"G\", \"_stat_site_order\": 1164}, {\"site\": 1169, \"wildtype\": \"I\", \"_stat_site_order\": 1165}, {\"site\": 1170, \"wildtype\": \"N\", \"_stat_site_order\": 1166}, {\"site\": 1171, \"wildtype\": \"A\", \"_stat_site_order\": 1167}, {\"site\": 1172, \"wildtype\": \"S\", \"_stat_site_order\": 1168}, {\"site\": 1173, \"wildtype\": \"V\", \"_stat_site_order\": 1169}, {\"site\": 1174, \"wildtype\": \"V\", \"_stat_site_order\": 1170}, {\"site\": 1175, \"wildtype\": \"N\", \"_stat_site_order\": 1171}, {\"site\": 1176, \"wildtype\": \"I\", \"_stat_site_order\": 1172}, {\"site\": 1177, \"wildtype\": \"Q\", \"_stat_site_order\": 1173}, {\"site\": 1178, \"wildtype\": \"K\", \"_stat_site_order\": 1174}, {\"site\": 1179, \"wildtype\": \"E\", \"_stat_site_order\": 1175}, {\"site\": 1180, \"wildtype\": \"I\", \"_stat_site_order\": 1176}, {\"site\": 1181, \"wildtype\": \"D\", \"_stat_site_order\": 1177}, {\"site\": 1182, \"wildtype\": \"R\", \"_stat_site_order\": 1178}, {\"site\": 1183, \"wildtype\": \"L\", \"_stat_site_order\": 1179}, {\"site\": 1184, \"wildtype\": \"N\", \"_stat_site_order\": 1180}, {\"site\": 1185, \"wildtype\": \"E\", \"_stat_site_order\": 1181}, {\"site\": 1186, \"wildtype\": \"V\", \"_stat_site_order\": 1182}, {\"site\": 1187, \"wildtype\": \"A\", \"_stat_site_order\": 1183}, {\"site\": 1188, \"wildtype\": \"K\", \"_stat_site_order\": 1184}, {\"site\": 1189, \"wildtype\": \"N\", \"_stat_site_order\": 1185}, {\"site\": 1190, \"wildtype\": \"L\", \"_stat_site_order\": 1186}, {\"site\": 1191, \"wildtype\": \"N\", \"_stat_site_order\": 1187}, {\"site\": 1192, \"wildtype\": \"E\", \"_stat_site_order\": 1188}, {\"site\": 1193, \"wildtype\": \"S\", \"_stat_site_order\": 1189}, {\"site\": 1194, \"wildtype\": \"L\", \"_stat_site_order\": 1190}, {\"site\": 1195, \"wildtype\": \"I\", \"_stat_site_order\": 1191}, {\"site\": 1196, \"wildtype\": \"D\", \"_stat_site_order\": 1192}, {\"site\": 1197, \"wildtype\": \"L\", \"_stat_site_order\": 1193}, {\"site\": 1198, \"wildtype\": \"Q\", \"_stat_site_order\": 1194}, {\"site\": 1199, \"wildtype\": \"E\", \"_stat_site_order\": 1195}, {\"site\": 1200, \"wildtype\": \"L\", \"_stat_site_order\": 1196}, {\"site\": 1201, \"wildtype\": \"G\", \"_stat_site_order\": 1197}, {\"site\": 1202, \"wildtype\": \"K\", \"_stat_site_order\": 1198}, {\"site\": 1203, \"wildtype\": \"Y\", \"_stat_site_order\": 1199}, {\"site\": 1204, \"wildtype\": \"E\", \"_stat_site_order\": 1200}, {\"site\": 1205, \"wildtype\": \"Q\", \"_stat_site_order\": 1201}, {\"site\": 1206, \"wildtype\": \"Y\", \"_stat_site_order\": 1202}, {\"site\": 1207, \"wildtype\": \"I\", \"_stat_site_order\": 1203}, {\"site\": 1208, \"wildtype\": \"K\", \"_stat_site_order\": 1204}, {\"site\": 1209, \"wildtype\": \"W\", \"_stat_site_order\": 1205}, {\"site\": 1210, \"wildtype\": \"P\", \"_stat_site_order\": 1206}, {\"site\": 1211, \"wildtype\": \"W\", \"_stat_site_order\": 1207}, {\"site\": 1212, \"wildtype\": \"Y\", \"_stat_site_order\": 1208}, {\"site\": 1213, \"wildtype\": \"I\", \"_stat_site_order\": 1209}, {\"site\": 1214, \"wildtype\": \"W\", \"_stat_site_order\": 1210}, {\"site\": 1215, \"wildtype\": \"L\", \"_stat_site_order\": 1211}, {\"site\": 1216, \"wildtype\": \"G\", \"_stat_site_order\": 1212}, {\"site\": 1217, \"wildtype\": \"F\", \"_stat_site_order\": 1213}, {\"site\": 1218, \"wildtype\": \"I\", \"_stat_site_order\": 1214}, {\"site\": 1219, \"wildtype\": \"A\", \"_stat_site_order\": 1215}, {\"site\": 1220, \"wildtype\": \"G\", \"_stat_site_order\": 1216}, {\"site\": 1221, \"wildtype\": \"L\", \"_stat_site_order\": 1217}, {\"site\": 1222, \"wildtype\": \"I\", \"_stat_site_order\": 1218}, {\"site\": 1223, \"wildtype\": \"A\", \"_stat_site_order\": 1219}, {\"site\": 1224, \"wildtype\": \"I\", \"_stat_site_order\": 1220}, {\"site\": 1225, \"wildtype\": \"V\", \"_stat_site_order\": 1221}, {\"site\": 1226, \"wildtype\": \"M\", \"_stat_site_order\": 1222}, {\"site\": 1227, \"wildtype\": \"V\", \"_stat_site_order\": 1223}, {\"site\": 1228, \"wildtype\": \"T\", \"_stat_site_order\": 1224}, {\"site\": 1229, \"wildtype\": \"I\", \"_stat_site_order\": 1225}, {\"site\": 1230, \"wildtype\": \"M\", \"_stat_site_order\": 1226}, {\"site\": 1231, \"wildtype\": \"L\", \"_stat_site_order\": 1227}, {\"site\": 1232, \"wildtype\": \"C\", \"_stat_site_order\": 1228}, {\"site\": 1233, \"wildtype\": \"C\", \"_stat_site_order\": 1229}, {\"site\": 1234, \"wildtype\": \"M\", \"_stat_site_order\": 1230}, {\"site\": 1235, \"wildtype\": \"T\", \"_stat_site_order\": 1231}, {\"site\": 1236, \"wildtype\": \"S\", \"_stat_site_order\": 1232}, {\"site\": 1237, \"wildtype\": \"C\", \"_stat_site_order\": 1233}, {\"site\": 1238, \"wildtype\": \"C\", \"_stat_site_order\": 1234}, {\"site\": 1239, \"wildtype\": \"S\", \"_stat_site_order\": 1235}, {\"site\": 1240, \"wildtype\": \"C\", \"_stat_site_order\": 1236}, {\"site\": 1241, \"wildtype\": \"L\", \"_stat_site_order\": 1237}, {\"site\": 1242, \"wildtype\": \"K\", \"_stat_site_order\": 1238}, {\"site\": 1243, \"wildtype\": \"G\", \"_stat_site_order\": 1239}, {\"site\": 1244, \"wildtype\": \"C\", \"_stat_site_order\": 1240}, {\"site\": 1245, \"wildtype\": \"C\", \"_stat_site_order\": 1241}, {\"site\": 1246, \"wildtype\": \"S\", \"_stat_site_order\": 1242}, {\"site\": 1247, \"wildtype\": \"C\", \"_stat_site_order\": 1243}, {\"site\": 1248, \"wildtype\": \"G\", \"_stat_site_order\": 1244}, {\"site\": 1249, \"wildtype\": \"S\", \"_stat_site_order\": 1245}, {\"site\": 1250, \"wildtype\": \"*\", \"_stat_site_order\": 1246}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -934,16 +871,9 @@
   },
   {
    "cell_type": "code",
-   "execution_count": 16,
+   "execution_count": 10,
    "id": "e06e0259-9ad4-4d3a-81bb-dbf38631d702",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:37:14.759387Z",
-     "iopub.status.busy": "2023-08-18T19:37:14.758796Z",
-     "iopub.status.idle": "2023-08-18T19:37:21.098361Z",
-     "shell.execute_reply": "2023-08-18T19:37:21.097467Z",
-     "shell.execute_reply.started": "2023-08-18T19:37:14.759347Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -952,28 +882,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-1ede67daf1114151969709479060504e.vega-embed {\n",
+       "  #altair-viz-320e7c8f5dee46809fea133128a599d4.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-1ede67daf1114151969709479060504e.vega-embed details,\n",
-       "  #altair-viz-1ede67daf1114151969709479060504e.vega-embed details summary {\n",
+       "  #altair-viz-320e7c8f5dee46809fea133128a599d4.vega-embed details,\n",
+       "  #altair-viz-320e7c8f5dee46809fea133128a599d4.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-1ede67daf1114151969709479060504e\"></div>\n",
+       "<div id=\"altair-viz-320e7c8f5dee46809fea133128a599d4\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-1ede67daf1114151969709479060504e\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-1ede67daf1114151969709479060504e\");\n",
+       "    if (outputDiv.id !== \"altair-viz-320e7c8f5dee46809fea133128a599d4\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-320e7c8f5dee46809fea133128a599d4\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -1009,19 +939,19 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_14\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"all\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}}, \"name\": \"view_13\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_21['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_22['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.641266135949879,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_23['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_25\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_24\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"all\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_21['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_22['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.641266135949879,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_23['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_25\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-bba4f8a09147f0e0e12310f5961c26ef\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_15\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_21['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_22['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.641266135949879,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_23['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_25\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"log2 fold change IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_21['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_22['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.641266135949879,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_23['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_25\"}}, {\"filter\": \"(datum['epitope'] === 'all')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"log2 fold change IC90\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 10.094253736362692, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"log2 fold change IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_21['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_22['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.641266135949879,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_23['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_25\"}}, {\"filter\": \"(datum['epitope'] === 'all')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_21['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_22['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.641266135949879,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_23['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_25\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-bba4f8a09147f0e0e12310f5961c26ef\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_25\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_14\", \"view_13\", \"view_15\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site log2 fold change IC90 statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_13\"]}, {\"name\": \"param_24\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_13\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -6.641266135949879], \"labels\": [\"yes\", \"no\"], \"name\": \"floor log2 fold change IC90 at zero\"}, \"value\": [{\"floor\": -6.641266135949879}], \"views\": [\"view_14\", \"view_13\", \"view_15\"]}, {\"name\": \"param_21\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 1.5161, \"min\": -3.3409, \"name\": \"minimum functional effect\"}, \"value\": [{\"cutoff\": -3.3409}], \"views\": [\"view_14\", \"view_13\", \"view_15\"]}, {\"name\": \"param_22\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": [{\"cutoff\": 1}], \"views\": [\"view_14\", \"view_13\", \"view_15\"]}, {\"name\": \"param_23\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 10.094253736362692, \"min\": -6.641266135949879, \"name\": \"minimum max of log2 fold change IC90 at site\"}, \"value\": [{\"cutoff\": -6.641266135949879}], \"views\": [\"view_14\", \"view_13\", \"view_15\"]}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-9631765c1c8eedabe994b76062594ede\": [{\"site\": 1, \"_stat_site_order\": 0}, {\"site\": 2, \"_stat_site_order\": 1}, {\"site\": 3, \"_stat_site_order\": 2}, {\"site\": 4, \"_stat_site_order\": 3}, {\"site\": 5, \"_stat_site_order\": 4}, {\"site\": 6, \"_stat_site_order\": 5}, {\"site\": 7, \"_stat_site_order\": 6}, {\"site\": 8, \"_stat_site_order\": 7}, {\"site\": 9, \"_stat_site_order\": 8}, {\"site\": 10, \"_stat_site_order\": 9}, {\"site\": 11, \"_stat_site_order\": 10}, {\"site\": 12, \"_stat_site_order\": 11}, {\"site\": 13, \"_stat_site_order\": 12}, {\"site\": 14, \"_stat_site_order\": 13}, {\"site\": 15, \"_stat_site_order\": 14}, {\"site\": 16, \"_stat_site_order\": 15}, {\"site\": 17, \"_stat_site_order\": 16}, {\"site\": 18, \"_stat_site_order\": 17}, {\"site\": 19, \"_stat_site_order\": 18}, {\"site\": 20, \"_stat_site_order\": 19}, {\"site\": 21, \"_stat_site_order\": 20}, {\"site\": 22, \"_stat_site_order\": 21}, {\"site\": 23, \"_stat_site_order\": 22}, {\"site\": 24, \"_stat_site_order\": 23}, {\"site\": 25, \"_stat_site_order\": 24}, {\"site\": 26, \"_stat_site_order\": 25}, {\"site\": 27, \"_stat_site_order\": 26}, {\"site\": 28, \"_stat_site_order\": 27}, {\"site\": 29, \"_stat_site_order\": 28}, {\"site\": 30, \"_stat_site_order\": 29}, {\"site\": 31, \"_stat_site_order\": 30}, {\"site\": 32, \"_stat_site_order\": 31}, {\"site\": 33, \"_stat_site_order\": 32}, {\"site\": 34, \"_stat_site_order\": 33}, {\"site\": 35, \"_stat_site_order\": 34}, {\"site\": 36, \"_stat_site_order\": 35}, {\"site\": 37, \"_stat_site_order\": 36}, {\"site\": 38, \"_stat_site_order\": 37}, {\"site\": 39, \"_stat_site_order\": 38}, {\"site\": 40, \"_stat_site_order\": 39}, {\"site\": 41, \"_stat_site_order\": 40}, {\"site\": 42, \"_stat_site_order\": 41}, {\"site\": 43, \"_stat_site_order\": 42}, {\"site\": 44, \"_stat_site_order\": 43}, {\"site\": 45, \"_stat_site_order\": 44}, {\"site\": 46, \"_stat_site_order\": 45}, {\"site\": 47, \"_stat_site_order\": 46}, {\"site\": 48, \"_stat_site_order\": 47}, {\"site\": 49, \"_stat_site_order\": 48}, {\"site\": 50, \"_stat_site_order\": 49}, {\"site\": 51, \"_stat_site_order\": 50}, {\"site\": 52, \"_stat_site_order\": 51}, {\"site\": 53, \"_stat_site_order\": 52}, {\"site\": 54, \"_stat_site_order\": 53}, {\"site\": 55, \"_stat_site_order\": 54}, {\"site\": 56, \"_stat_site_order\": 55}, {\"site\": 57, \"_stat_site_order\": 56}, {\"site\": 58, \"_stat_site_order\": 57}, {\"site\": 59, \"_stat_site_order\": 58}, {\"site\": 60, \"_stat_site_order\": 59}, {\"site\": 61, \"_stat_site_order\": 60}, {\"site\": 62, \"_stat_site_order\": 61}, {\"site\": 63, \"_stat_site_order\": 62}, {\"site\": 64, \"_stat_site_order\": 63}, {\"site\": 65, \"_stat_site_order\": 64}, {\"site\": 66, \"_stat_site_order\": 65}, {\"site\": 67, \"_stat_site_order\": 66}, {\"site\": 68, \"_stat_site_order\": 67}, {\"site\": 69, \"_stat_site_order\": 68}, {\"site\": 70, \"_stat_site_order\": 69}, {\"site\": 71, \"_stat_site_order\": 70}, {\"site\": 72, \"_stat_site_order\": 71}, {\"site\": 73, \"_stat_site_order\": 72}, {\"site\": 74, \"_stat_site_order\": 73}, {\"site\": 75, \"_stat_site_order\": 74}, {\"site\": 76, \"_stat_site_order\": 75}, {\"site\": 77, \"_stat_site_order\": 76}, {\"site\": 78, \"_stat_site_order\": 77}, {\"site\": 79, \"_stat_site_order\": 78}, {\"site\": 80, \"_stat_site_order\": 79}, {\"site\": 81, \"_stat_site_order\": 80}, {\"site\": 82, \"_stat_site_order\": 81}, {\"site\": 83, \"_stat_site_order\": 82}, {\"site\": 84, \"_stat_site_order\": 83}, {\"site\": 85, \"_stat_site_order\": 84}, {\"site\": 86, \"_stat_site_order\": 85}, {\"site\": 87, \"_stat_site_order\": 86}, {\"site\": 88, \"_stat_site_order\": 87}, {\"site\": 89, \"_stat_site_order\": 88}, {\"site\": 90, \"_stat_site_order\": 89}, {\"site\": 91, \"_stat_site_order\": 90}, {\"site\": 92, \"_stat_site_order\": 91}, {\"site\": 93, \"_stat_site_order\": 92}, {\"site\": 94, \"_stat_site_order\": 93}, {\"site\": 95, \"_stat_site_order\": 94}, {\"site\": 96, \"_stat_site_order\": 95}, {\"site\": 97, \"_stat_site_order\": 96}, {\"site\": 98, \"_stat_site_order\": 97}, {\"site\": 99, \"_stat_site_order\": 98}, {\"site\": 100, \"_stat_site_order\": 99}, {\"site\": 101, \"_stat_site_order\": 100}, {\"site\": 102, \"_stat_site_order\": 101}, {\"site\": 103, \"_stat_site_order\": 102}, {\"site\": 104, \"_stat_site_order\": 103}, {\"site\": 105, \"_stat_site_order\": 104}, {\"site\": 106, \"_stat_site_order\": 105}, {\"site\": 107, \"_stat_site_order\": 106}, {\"site\": 108, \"_stat_site_order\": 107}, {\"site\": 109, \"_stat_site_order\": 108}, {\"site\": 110, \"_stat_site_order\": 109}, {\"site\": 111, \"_stat_site_order\": 110}, {\"site\": 112, \"_stat_site_order\": 111}, {\"site\": 113, \"_stat_site_order\": 112}, {\"site\": 114, \"_stat_site_order\": 113}, {\"site\": 115, \"_stat_site_order\": 114}, {\"site\": 116, \"_stat_site_order\": 115}, {\"site\": 117, \"_stat_site_order\": 116}, {\"site\": 118, \"_stat_site_order\": 117}, {\"site\": 119, \"_stat_site_order\": 118}, {\"site\": 120, \"_stat_site_order\": 119}, {\"site\": 121, \"_stat_site_order\": 120}, {\"site\": 122, \"_stat_site_order\": 121}, {\"site\": 123, \"_stat_site_order\": 122}, {\"site\": 124, \"_stat_site_order\": 123}, {\"site\": 125, \"_stat_site_order\": 124}, {\"site\": 126, \"_stat_site_order\": 125}, {\"site\": 127, \"_stat_site_order\": 126}, {\"site\": 128, \"_stat_site_order\": 127}, {\"site\": 129, \"_stat_site_order\": 128}, {\"site\": 130, \"_stat_site_order\": 129}, {\"site\": 131, \"_stat_site_order\": 130}, {\"site\": 132, \"_stat_site_order\": 131}, {\"site\": 133, \"_stat_site_order\": 132}, {\"site\": 134, \"_stat_site_order\": 133}, {\"site\": 135, \"_stat_site_order\": 134}, {\"site\": 136, \"_stat_site_order\": 135}, {\"site\": 137, \"_stat_site_order\": 136}, {\"site\": 138, \"_stat_site_order\": 137}, {\"site\": 139, \"_stat_site_order\": 138}, {\"site\": 140, \"_stat_site_order\": 139}, {\"site\": 141, \"_stat_site_order\": 140}, {\"site\": 142, \"_stat_site_order\": 141}, {\"site\": 143, \"_stat_site_order\": 142}, {\"site\": 144, \"_stat_site_order\": 143}, {\"site\": 145, \"_stat_site_order\": 144}, {\"site\": 146, \"_stat_site_order\": 145}, {\"site\": 147, \"_stat_site_order\": 146}, {\"site\": 148, \"_stat_site_order\": 147}, {\"site\": 149, \"_stat_site_order\": 148}, {\"site\": 150, \"_stat_site_order\": 149}, {\"site\": 151, \"_stat_site_order\": 150}, {\"site\": 152, \"_stat_site_order\": 151}, {\"site\": 153, \"_stat_site_order\": 152}, {\"site\": 154, \"_stat_site_order\": 153}, {\"site\": 155, \"_stat_site_order\": 154}, {\"site\": 156, \"_stat_site_order\": 155}, {\"site\": 157, \"_stat_site_order\": 156}, {\"site\": 158, \"_stat_site_order\": 157}, {\"site\": 159, \"_stat_site_order\": 158}, {\"site\": 160, \"_stat_site_order\": 159}, {\"site\": 161, \"_stat_site_order\": 160}, {\"site\": 162, \"_stat_site_order\": 161}, {\"site\": 163, \"_stat_site_order\": 162}, {\"site\": 164, \"_stat_site_order\": 163}, {\"site\": 165, \"_stat_site_order\": 164}, {\"site\": 166, \"_stat_site_order\": 165}, {\"site\": 167, \"_stat_site_order\": 166}, {\"site\": 168, \"_stat_site_order\": 167}, {\"site\": 169, \"_stat_site_order\": 168}, {\"site\": 170, \"_stat_site_order\": 169}, {\"site\": 171, \"_stat_site_order\": 170}, {\"site\": 172, \"_stat_site_order\": 171}, {\"site\": 173, \"_stat_site_order\": 172}, {\"site\": 174, \"_stat_site_order\": 173}, {\"site\": 175, \"_stat_site_order\": 174}, {\"site\": 176, \"_stat_site_order\": 175}, {\"site\": 177, \"_stat_site_order\": 176}, {\"site\": 178, \"_stat_site_order\": 177}, {\"site\": 179, \"_stat_site_order\": 178}, {\"site\": 180, \"_stat_site_order\": 179}, {\"site\": 181, \"_stat_site_order\": 180}, {\"site\": 182, \"_stat_site_order\": 181}, {\"site\": 183, \"_stat_site_order\": 182}, {\"site\": 184, \"_stat_site_order\": 183}, {\"site\": 185, \"_stat_site_order\": 184}, {\"site\": 186, \"_stat_site_order\": 185}, {\"site\": 187, \"_stat_site_order\": 186}, {\"site\": 188, \"_stat_site_order\": 187}, {\"site\": 189, \"_stat_site_order\": 188}, {\"site\": 190, \"_stat_site_order\": 189}, {\"site\": 191, \"_stat_site_order\": 190}, {\"site\": 192, \"_stat_site_order\": 191}, {\"site\": 193, \"_stat_site_order\": 192}, {\"site\": 194, \"_stat_site_order\": 193}, {\"site\": 195, \"_stat_site_order\": 194}, {\"site\": 196, \"_stat_site_order\": 195}, {\"site\": 197, \"_stat_site_order\": 196}, {\"site\": 198, \"_stat_site_order\": 197}, {\"site\": 199, \"_stat_site_order\": 198}, {\"site\": 200, \"_stat_site_order\": 199}, {\"site\": 201, \"_stat_site_order\": 200}, {\"site\": 202, \"_stat_site_order\": 201}, {\"site\": 203, \"_stat_site_order\": 202}, {\"site\": 204, \"_stat_site_order\": 203}, {\"site\": 205, \"_stat_site_order\": 204}, {\"site\": 206, \"_stat_site_order\": 205}, {\"site\": 207, \"_stat_site_order\": 206}, {\"site\": 208, \"_stat_site_order\": 207}, {\"site\": 209, \"_stat_site_order\": 208}, {\"site\": 210, \"_stat_site_order\": 209}, {\"site\": 211, \"_stat_site_order\": 210}, {\"site\": 212, \"_stat_site_order\": 211}, {\"site\": 213, \"_stat_site_order\": 212}, {\"site\": 214, \"_stat_site_order\": 213}, {\"site\": 215, \"_stat_site_order\": 214}, {\"site\": 216, \"_stat_site_order\": 215}, {\"site\": 217, \"_stat_site_order\": 216}, {\"site\": 218, \"_stat_site_order\": 217}, {\"site\": 219, \"_stat_site_order\": 218}, {\"site\": 220, \"_stat_site_order\": 219}, {\"site\": 221, \"_stat_site_order\": 220}, {\"site\": 222, \"_stat_site_order\": 221}, {\"site\": 223, \"_stat_site_order\": 222}, {\"site\": 224, \"_stat_site_order\": 223}, {\"site\": 225, \"_stat_site_order\": 224}, {\"site\": 226, \"_stat_site_order\": 225}, {\"site\": 227, \"_stat_site_order\": 226}, {\"site\": 228, \"_stat_site_order\": 227}, {\"site\": 229, \"_stat_site_order\": 228}, {\"site\": 230, \"_stat_site_order\": 229}, {\"site\": 231, \"_stat_site_order\": 230}, {\"site\": 232, \"_stat_site_order\": 231}, {\"site\": 233, \"_stat_site_order\": 232}, {\"site\": 234, \"_stat_site_order\": 233}, {\"site\": 235, \"_stat_site_order\": 234}, {\"site\": 236, \"_stat_site_order\": 235}, {\"site\": 237, \"_stat_site_order\": 236}, {\"site\": 238, \"_stat_site_order\": 237}, {\"site\": 239, \"_stat_site_order\": 238}, {\"site\": 240, \"_stat_site_order\": 239}, {\"site\": 241, \"_stat_site_order\": 240}, {\"site\": 242, \"_stat_site_order\": 241}, {\"site\": 243, \"_stat_site_order\": 242}, {\"site\": 244, \"_stat_site_order\": 243}, {\"site\": 245, \"_stat_site_order\": 244}, {\"site\": 246, \"_stat_site_order\": 245}, {\"site\": 247, \"_stat_site_order\": 246}, {\"site\": 248, \"_stat_site_order\": 247}, {\"site\": 249, \"_stat_site_order\": 248}, {\"site\": 250, \"_stat_site_order\": 249}, {\"site\": 251, \"_stat_site_order\": 250}, {\"site\": 252, \"_stat_site_order\": 251}, {\"site\": 253, \"_stat_site_order\": 252}, {\"site\": 254, \"_stat_site_order\": 253}, {\"site\": 255, \"_stat_site_order\": 254}, {\"site\": 256, \"_stat_site_order\": 255}, {\"site\": 257, \"_stat_site_order\": 256}, {\"site\": 258, \"_stat_site_order\": 257}, {\"site\": 259, \"_stat_site_order\": 258}, {\"site\": 260, \"_stat_site_order\": 259}, {\"site\": 261, \"_stat_site_order\": 260}, {\"site\": 262, \"_stat_site_order\": 261}, {\"site\": 263, \"_stat_site_order\": 262}, {\"site\": 264, \"_stat_site_order\": 263}, {\"site\": 265, \"_stat_site_order\": 264}, {\"site\": 266, \"_stat_site_order\": 265}, {\"site\": 267, \"_stat_site_order\": 266}, {\"site\": 268, \"_stat_site_order\": 267}, {\"site\": 269, \"_stat_site_order\": 268}, {\"site\": 270, \"_stat_site_order\": 269}, {\"site\": 271, \"_stat_site_order\": 270}, {\"site\": 272, \"_stat_site_order\": 271}, {\"site\": 273, \"_stat_site_order\": 272}, {\"site\": 274, \"_stat_site_order\": 273}, {\"site\": 275, \"_stat_site_order\": 274}, {\"site\": 276, \"_stat_site_order\": 275}, {\"site\": 277, \"_stat_site_order\": 276}, {\"site\": 278, \"_stat_site_order\": 277}, {\"site\": 279, \"_stat_site_order\": 278}, {\"site\": 280, \"_stat_site_order\": 279}, {\"site\": 281, \"_stat_site_order\": 280}, {\"site\": 282, \"_stat_site_order\": 281}, {\"site\": 283, \"_stat_site_order\": 282}, {\"site\": 284, \"_stat_site_order\": 283}, {\"site\": 285, \"_stat_site_order\": 284}, {\"site\": 286, \"_stat_site_order\": 285}, {\"site\": 287, \"_stat_site_order\": 286}, {\"site\": 288, \"_stat_site_order\": 287}, {\"site\": 289, \"_stat_site_order\": 288}, {\"site\": 290, \"_stat_site_order\": 289}, {\"site\": 291, \"_stat_site_order\": 290}, {\"site\": 292, \"_stat_site_order\": 291}, {\"site\": 293, \"_stat_site_order\": 292}, {\"site\": 294, \"_stat_site_order\": 293}, {\"site\": 295, \"_stat_site_order\": 294}, {\"site\": 296, \"_stat_site_order\": 295}, {\"site\": 297, \"_stat_site_order\": 296}, {\"site\": 298, \"_stat_site_order\": 297}, {\"site\": 299, \"_stat_site_order\": 298}, {\"site\": 300, \"_stat_site_order\": 299}, {\"site\": 301, \"_stat_site_order\": 300}, {\"site\": 302, \"_stat_site_order\": 301}, {\"site\": 303, \"_stat_site_order\": 302}, {\"site\": 304, \"_stat_site_order\": 303}, {\"site\": 305, \"_stat_site_order\": 304}, {\"site\": 306, \"_stat_site_order\": 305}, {\"site\": 307, \"_stat_site_order\": 306}, {\"site\": 308, \"_stat_site_order\": 307}, {\"site\": 309, \"_stat_site_order\": 308}, {\"site\": 310, \"_stat_site_order\": 309}, {\"site\": 311, \"_stat_site_order\": 310}, {\"site\": 312, \"_stat_site_order\": 311}, {\"site\": 313, \"_stat_site_order\": 312}, {\"site\": 314, \"_stat_site_order\": 313}, {\"site\": 315, \"_stat_site_order\": 314}, {\"site\": 316, \"_stat_site_order\": 315}, {\"site\": 317, \"_stat_site_order\": 316}, {\"site\": 318, \"_stat_site_order\": 317}, {\"site\": 319, \"_stat_site_order\": 318}, {\"site\": 320, \"_stat_site_order\": 319}, {\"site\": 321, \"_stat_site_order\": 320}, {\"site\": 322, \"_stat_site_order\": 321}, {\"site\": 323, \"_stat_site_order\": 322}, {\"site\": 324, \"_stat_site_order\": 323}, {\"site\": 325, \"_stat_site_order\": 324}, {\"site\": 326, \"_stat_site_order\": 325}, {\"site\": 327, \"_stat_site_order\": 326}, {\"site\": 328, \"_stat_site_order\": 327}, {\"site\": 329, \"_stat_site_order\": 328}, {\"site\": 330, \"_stat_site_order\": 329}, {\"site\": 331, \"_stat_site_order\": 330}, {\"site\": 332, \"_stat_site_order\": 331}, {\"site\": 333, \"_stat_site_order\": 332}, {\"site\": 334, \"_stat_site_order\": 333}, {\"site\": 335, \"_stat_site_order\": 334}, {\"site\": 336, \"_stat_site_order\": 335}, {\"site\": 337, \"_stat_site_order\": 336}, {\"site\": 338, \"_stat_site_order\": 337}, {\"site\": 339, \"_stat_site_order\": 338}, {\"site\": 340, \"_stat_site_order\": 339}, {\"site\": 341, \"_stat_site_order\": 340}, {\"site\": 342, \"_stat_site_order\": 341}, {\"site\": 343, \"_stat_site_order\": 342}, {\"site\": 345, \"_stat_site_order\": 343}, {\"site\": 346, \"_stat_site_order\": 344}, {\"site\": 347, \"_stat_site_order\": 345}, {\"site\": 348, \"_stat_site_order\": 346}, {\"site\": 349, \"_stat_site_order\": 347}, {\"site\": 350, \"_stat_site_order\": 348}, {\"site\": 351, \"_stat_site_order\": 349}, {\"site\": 352, \"_stat_site_order\": 350}, {\"site\": 353, \"_stat_site_order\": 351}, {\"site\": 354, \"_stat_site_order\": 352}, {\"site\": 355, \"_stat_site_order\": 353}, {\"site\": 356, \"_stat_site_order\": 354}, {\"site\": 357, \"_stat_site_order\": 355}, {\"site\": 358, \"_stat_site_order\": 356}, {\"site\": 359, \"_stat_site_order\": 357}, {\"site\": 360, \"_stat_site_order\": 358}, {\"site\": 361, \"_stat_site_order\": 359}, {\"site\": 362, \"_stat_site_order\": 360}, {\"site\": 363, \"_stat_site_order\": 361}, {\"site\": 364, \"_stat_site_order\": 362}, {\"site\": 365, \"_stat_site_order\": 363}, {\"site\": 366, \"_stat_site_order\": 364}, {\"site\": 367, \"_stat_site_order\": 365}, {\"site\": 368, \"_stat_site_order\": 366}, {\"site\": 369, \"_stat_site_order\": 367}, {\"site\": 370, \"_stat_site_order\": 368}, {\"site\": 371, \"_stat_site_order\": 369}, {\"site\": 372, \"_stat_site_order\": 370}, {\"site\": 373, \"_stat_site_order\": 371}, {\"site\": 374, \"_stat_site_order\": 372}, {\"site\": 375, \"_stat_site_order\": 373}, {\"site\": 376, \"_stat_site_order\": 374}, {\"site\": 377, \"_stat_site_order\": 375}, {\"site\": 378, \"_stat_site_order\": 376}, {\"site\": 379, \"_stat_site_order\": 377}, {\"site\": 380, \"_stat_site_order\": 378}, {\"site\": 381, \"_stat_site_order\": 379}, {\"site\": 382, \"_stat_site_order\": 380}, {\"site\": 383, \"_stat_site_order\": 381}, {\"site\": 384, \"_stat_site_order\": 382}, {\"site\": 385, \"_stat_site_order\": 383}, {\"site\": 386, \"_stat_site_order\": 384}, {\"site\": 387, \"_stat_site_order\": 385}, {\"site\": 388, \"_stat_site_order\": 386}, {\"site\": 389, \"_stat_site_order\": 387}, {\"site\": 390, \"_stat_site_order\": 388}, {\"site\": 391, \"_stat_site_order\": 389}, {\"site\": 392, \"_stat_site_order\": 390}, {\"site\": 393, \"_stat_site_order\": 391}, {\"site\": 394, \"_stat_site_order\": 392}, {\"site\": 395, \"_stat_site_order\": 393}, {\"site\": 396, \"_stat_site_order\": 394}, {\"site\": 397, \"_stat_site_order\": 395}, {\"site\": 398, \"_stat_site_order\": 396}, {\"site\": 399, \"_stat_site_order\": 397}, {\"site\": 400, \"_stat_site_order\": 398}, {\"site\": 401, \"_stat_site_order\": 399}, {\"site\": 402, \"_stat_site_order\": 400}, {\"site\": 403, \"_stat_site_order\": 401}, {\"site\": 404, \"_stat_site_order\": 402}, {\"site\": 405, \"_stat_site_order\": 403}, {\"site\": 406, \"_stat_site_order\": 404}, {\"site\": 407, \"_stat_site_order\": 405}, {\"site\": 408, \"_stat_site_order\": 406}, {\"site\": 409, \"_stat_site_order\": 407}, {\"site\": 410, \"_stat_site_order\": 408}, {\"site\": 411, \"_stat_site_order\": 409}, {\"site\": 412, \"_stat_site_order\": 410}, {\"site\": 413, \"_stat_site_order\": 411}, {\"site\": 414, \"_stat_site_order\": 412}, {\"site\": 415, \"_stat_site_order\": 413}, {\"site\": 416, \"_stat_site_order\": 414}, {\"site\": 417, \"_stat_site_order\": 415}, {\"site\": 418, \"_stat_site_order\": 416}, {\"site\": 419, \"_stat_site_order\": 417}, {\"site\": 420, \"_stat_site_order\": 418}, {\"site\": 421, \"_stat_site_order\": 419}, {\"site\": 422, \"_stat_site_order\": 420}, {\"site\": 423, \"_stat_site_order\": 421}, {\"site\": 424, \"_stat_site_order\": 422}, {\"site\": 425, \"_stat_site_order\": 423}, {\"site\": 426, \"_stat_site_order\": 424}, {\"site\": 427, \"_stat_site_order\": 425}, {\"site\": 428, \"_stat_site_order\": 426}, {\"site\": 429, \"_stat_site_order\": 427}, {\"site\": 430, \"_stat_site_order\": 428}, {\"site\": 431, \"_stat_site_order\": 429}, {\"site\": 432, \"_stat_site_order\": 430}, {\"site\": 433, \"_stat_site_order\": 431}, {\"site\": 434, \"_stat_site_order\": 432}, {\"site\": 435, \"_stat_site_order\": 433}, {\"site\": 436, \"_stat_site_order\": 434}, {\"site\": 437, \"_stat_site_order\": 435}, {\"site\": 438, \"_stat_site_order\": 436}, {\"site\": 439, \"_stat_site_order\": 437}, {\"site\": 440, \"_stat_site_order\": 438}, {\"site\": 441, \"_stat_site_order\": 439}, {\"site\": 442, \"_stat_site_order\": 440}, {\"site\": 443, \"_stat_site_order\": 441}, {\"site\": 444, \"_stat_site_order\": 442}, {\"site\": 445, \"_stat_site_order\": 443}, {\"site\": 446, \"_stat_site_order\": 444}, {\"site\": 447, \"_stat_site_order\": 445}, {\"site\": 448, \"_stat_site_order\": 446}, {\"site\": 449, \"_stat_site_order\": 447}, {\"site\": 450, \"_stat_site_order\": 448}, {\"site\": 451, \"_stat_site_order\": 449}, {\"site\": 452, \"_stat_site_order\": 450}, {\"site\": 453, \"_stat_site_order\": 451}, {\"site\": 454, \"_stat_site_order\": 452}, {\"site\": 455, \"_stat_site_order\": 453}, {\"site\": 456, \"_stat_site_order\": 454}, {\"site\": 457, \"_stat_site_order\": 455}, {\"site\": 458, \"_stat_site_order\": 456}, {\"site\": 459, \"_stat_site_order\": 457}, {\"site\": 460, \"_stat_site_order\": 458}, {\"site\": 461, \"_stat_site_order\": 459}, {\"site\": 462, \"_stat_site_order\": 460}, {\"site\": 463, \"_stat_site_order\": 461}, {\"site\": 464, \"_stat_site_order\": 462}, {\"site\": 465, \"_stat_site_order\": 463}, {\"site\": 466, \"_stat_site_order\": 464}, {\"site\": 467, \"_stat_site_order\": 465}, {\"site\": 468, \"_stat_site_order\": 466}, {\"site\": 469, \"_stat_site_order\": 467}, {\"site\": 470, \"_stat_site_order\": 468}, {\"site\": 471, \"_stat_site_order\": 469}, {\"site\": 472, \"_stat_site_order\": 470}, {\"site\": 473, \"_stat_site_order\": 471}, {\"site\": 474, \"_stat_site_order\": 472}, {\"site\": 475, \"_stat_site_order\": 473}, {\"site\": 476, \"_stat_site_order\": 474}, {\"site\": 477, \"_stat_site_order\": 475}, {\"site\": 478, \"_stat_site_order\": 476}, {\"site\": 479, \"_stat_site_order\": 477}, {\"site\": 480, \"_stat_site_order\": 478}, {\"site\": 481, \"_stat_site_order\": 479}, {\"site\": 482, \"_stat_site_order\": 480}, {\"site\": 483, \"_stat_site_order\": 481}, {\"site\": 484, \"_stat_site_order\": 482}, {\"site\": 485, \"_stat_site_order\": 483}, {\"site\": 486, \"_stat_site_order\": 484}, {\"site\": 487, \"_stat_site_order\": 485}, {\"site\": 488, \"_stat_site_order\": 486}, {\"site\": 489, \"_stat_site_order\": 487}, {\"site\": 490, \"_stat_site_order\": 488}, {\"site\": 491, \"_stat_site_order\": 489}, {\"site\": 492, \"_stat_site_order\": 490}, {\"site\": 493, \"_stat_site_order\": 491}, {\"site\": 494, \"_stat_site_order\": 492}, {\"site\": 495, \"_stat_site_order\": 493}, {\"site\": 496, \"_stat_site_order\": 494}, {\"site\": 497, \"_stat_site_order\": 495}, {\"site\": 498, \"_stat_site_order\": 496}, {\"site\": 499, \"_stat_site_order\": 497}, {\"site\": 500, \"_stat_site_order\": 498}, {\"site\": 501, \"_stat_site_order\": 499}, {\"site\": 502, \"_stat_site_order\": 500}, {\"site\": 503, \"_stat_site_order\": 501}, {\"site\": 504, \"_stat_site_order\": 502}, {\"site\": 505, \"_stat_site_order\": 503}, {\"site\": 506, \"_stat_site_order\": 504}, {\"site\": 507, \"_stat_site_order\": 505}, {\"site\": 508, \"_stat_site_order\": 506}, {\"site\": 509, \"_stat_site_order\": 507}, {\"site\": 510, \"_stat_site_order\": 508}, {\"site\": 511, \"_stat_site_order\": 509}, {\"site\": 512, \"_stat_site_order\": 510}, {\"site\": 513, \"_stat_site_order\": 511}, {\"site\": 514, \"_stat_site_order\": 512}, {\"site\": 515, \"_stat_site_order\": 513}, {\"site\": 516, \"_stat_site_order\": 514}, {\"site\": 517, \"_stat_site_order\": 515}, {\"site\": 518, \"_stat_site_order\": 516}, {\"site\": 519, \"_stat_site_order\": 517}, {\"site\": 520, \"_stat_site_order\": 518}, {\"site\": 521, \"_stat_site_order\": 519}, {\"site\": 522, \"_stat_site_order\": 520}, {\"site\": 523, \"_stat_site_order\": 521}, {\"site\": 524, \"_stat_site_order\": 522}, {\"site\": 525, \"_stat_site_order\": 523}, {\"site\": 526, \"_stat_site_order\": 524}, {\"site\": 527, \"_stat_site_order\": 525}, {\"site\": 528, \"_stat_site_order\": 526}, {\"site\": 529, \"_stat_site_order\": 527}, {\"site\": 530, \"_stat_site_order\": 528}, {\"site\": 531, \"_stat_site_order\": 529}, {\"site\": 532, \"_stat_site_order\": 530}, {\"site\": 533, \"_stat_site_order\": 531}, {\"site\": 534, \"_stat_site_order\": 532}, {\"site\": 535, \"_stat_site_order\": 533}, {\"site\": 536, \"_stat_site_order\": 534}, {\"site\": 537, \"_stat_site_order\": 535}, {\"site\": 538, \"_stat_site_order\": 536}, {\"site\": 539, \"_stat_site_order\": 537}, {\"site\": 540, \"_stat_site_order\": 538}, {\"site\": 541, \"_stat_site_order\": 539}, {\"site\": 542, \"_stat_site_order\": 540}, {\"site\": 543, \"_stat_site_order\": 541}, {\"site\": 544, \"_stat_site_order\": 542}, {\"site\": 545, \"_stat_site_order\": 543}, {\"site\": 546, \"_stat_site_order\": 544}, {\"site\": 547, \"_stat_site_order\": 545}, {\"site\": 548, \"_stat_site_order\": 546}, {\"site\": 549, \"_stat_site_order\": 547}, {\"site\": 550, \"_stat_site_order\": 548}, {\"site\": 551, \"_stat_site_order\": 549}, {\"site\": 552, \"_stat_site_order\": 550}, {\"site\": 553, \"_stat_site_order\": 551}, {\"site\": 554, \"_stat_site_order\": 552}, {\"site\": 555, \"_stat_site_order\": 553}, {\"site\": 556, \"_stat_site_order\": 554}, {\"site\": 557, \"_stat_site_order\": 555}, {\"site\": 558, \"_stat_site_order\": 556}, {\"site\": 559, \"_stat_site_order\": 557}, {\"site\": 560, \"_stat_site_order\": 558}, {\"site\": 561, \"_stat_site_order\": 559}, {\"site\": 562, \"_stat_site_order\": 560}, {\"site\": 563, \"_stat_site_order\": 561}, {\"site\": 564, \"_stat_site_order\": 562}, {\"site\": 565, \"_stat_site_order\": 563}, {\"site\": 566, \"_stat_site_order\": 564}, {\"site\": 567, \"_stat_site_order\": 565}, {\"site\": 568, \"_stat_site_order\": 566}, {\"site\": 569, \"_stat_site_order\": 567}, {\"site\": 570, \"_stat_site_order\": 568}, {\"site\": 571, \"_stat_site_order\": 569}, {\"site\": 572, \"_stat_site_order\": 570}, {\"site\": 573, \"_stat_site_order\": 571}, {\"site\": 574, \"_stat_site_order\": 572}, {\"site\": 575, \"_stat_site_order\": 573}, {\"site\": 576, \"_stat_site_order\": 574}, {\"site\": 577, \"_stat_site_order\": 575}, {\"site\": 578, \"_stat_site_order\": 576}, {\"site\": 579, \"_stat_site_order\": 577}, {\"site\": 580, \"_stat_site_order\": 578}, {\"site\": 581, \"_stat_site_order\": 579}, {\"site\": 582, \"_stat_site_order\": 580}, {\"site\": 583, \"_stat_site_order\": 581}, {\"site\": 584, \"_stat_site_order\": 582}, {\"site\": 585, \"_stat_site_order\": 583}, {\"site\": 586, \"_stat_site_order\": 584}, {\"site\": 587, \"_stat_site_order\": 585}, {\"site\": 588, \"_stat_site_order\": 586}, {\"site\": 589, \"_stat_site_order\": 587}, {\"site\": 590, \"_stat_site_order\": 588}, {\"site\": 591, \"_stat_site_order\": 589}, {\"site\": 592, \"_stat_site_order\": 590}, {\"site\": 593, \"_stat_site_order\": 591}, {\"site\": 594, \"_stat_site_order\": 592}, {\"site\": 595, \"_stat_site_order\": 593}, {\"site\": 596, \"_stat_site_order\": 594}, {\"site\": 597, \"_stat_site_order\": 595}, {\"site\": 598, \"_stat_site_order\": 596}, {\"site\": 599, \"_stat_site_order\": 597}, {\"site\": 600, \"_stat_site_order\": 598}, {\"site\": 601, \"_stat_site_order\": 599}, {\"site\": 602, \"_stat_site_order\": 600}, {\"site\": 603, \"_stat_site_order\": 601}, {\"site\": 604, \"_stat_site_order\": 602}, {\"site\": 605, \"_stat_site_order\": 603}, {\"site\": 606, \"_stat_site_order\": 604}, {\"site\": 607, \"_stat_site_order\": 605}, {\"site\": 608, \"_stat_site_order\": 606}, {\"site\": 609, \"_stat_site_order\": 607}, {\"site\": 610, \"_stat_site_order\": 608}, {\"site\": 611, \"_stat_site_order\": 609}, {\"site\": 612, \"_stat_site_order\": 610}, {\"site\": 613, \"_stat_site_order\": 611}, {\"site\": 614, \"_stat_site_order\": 612}, {\"site\": 615, \"_stat_site_order\": 613}, {\"site\": 616, \"_stat_site_order\": 614}, {\"site\": 617, \"_stat_site_order\": 615}, {\"site\": 618, \"_stat_site_order\": 616}, {\"site\": 619, \"_stat_site_order\": 617}, {\"site\": 620, \"_stat_site_order\": 618}, {\"site\": 621, \"_stat_site_order\": 619}, {\"site\": 622, \"_stat_site_order\": 620}, {\"site\": 623, \"_stat_site_order\": 621}, {\"site\": 624, \"_stat_site_order\": 622}, {\"site\": 625, \"_stat_site_order\": 623}, {\"site\": 626, \"_stat_site_order\": 624}, {\"site\": 627, \"_stat_site_order\": 625}, {\"site\": 628, \"_stat_site_order\": 626}, {\"site\": 629, \"_stat_site_order\": 627}, {\"site\": 630, \"_stat_site_order\": 628}, {\"site\": 631, \"_stat_site_order\": 629}, {\"site\": 632, \"_stat_site_order\": 630}, {\"site\": 633, \"_stat_site_order\": 631}, {\"site\": 634, \"_stat_site_order\": 632}, {\"site\": 635, \"_stat_site_order\": 633}, {\"site\": 636, \"_stat_site_order\": 634}, {\"site\": 637, \"_stat_site_order\": 635}, {\"site\": 638, \"_stat_site_order\": 636}, {\"site\": 639, \"_stat_site_order\": 637}, {\"site\": 640, \"_stat_site_order\": 638}, {\"site\": 641, \"_stat_site_order\": 639}, {\"site\": 642, \"_stat_site_order\": 640}, {\"site\": 643, \"_stat_site_order\": 641}, {\"site\": 644, \"_stat_site_order\": 642}, {\"site\": 645, \"_stat_site_order\": 643}, {\"site\": 646, \"_stat_site_order\": 644}, {\"site\": 647, \"_stat_site_order\": 645}, {\"site\": 648, \"_stat_site_order\": 646}, {\"site\": 649, \"_stat_site_order\": 647}, {\"site\": 650, \"_stat_site_order\": 648}, {\"site\": 651, \"_stat_site_order\": 649}, {\"site\": 652, \"_stat_site_order\": 650}, {\"site\": 653, \"_stat_site_order\": 651}, {\"site\": 654, \"_stat_site_order\": 652}, {\"site\": 655, \"_stat_site_order\": 653}, {\"site\": 656, \"_stat_site_order\": 654}, {\"site\": 657, \"_stat_site_order\": 655}, {\"site\": 658, \"_stat_site_order\": 656}, {\"site\": 659, \"_stat_site_order\": 657}, {\"site\": 660, \"_stat_site_order\": 658}, {\"site\": 661, \"_stat_site_order\": 659}, {\"site\": 662, \"_stat_site_order\": 660}, {\"site\": 663, \"_stat_site_order\": 661}, {\"site\": 664, \"_stat_site_order\": 662}, {\"site\": 665, \"_stat_site_order\": 663}, {\"site\": 666, \"_stat_site_order\": 664}, {\"site\": 667, \"_stat_site_order\": 665}, {\"site\": 668, \"_stat_site_order\": 666}, {\"site\": 669, \"_stat_site_order\": 667}, {\"site\": 670, \"_stat_site_order\": 668}, {\"site\": 671, \"_stat_site_order\": 669}, {\"site\": 672, \"_stat_site_order\": 670}, {\"site\": 673, \"_stat_site_order\": 671}, {\"site\": 674, \"_stat_site_order\": 672}, {\"site\": 675, \"_stat_site_order\": 673}, {\"site\": 676, \"_stat_site_order\": 674}, {\"site\": 677, \"_stat_site_order\": 675}, {\"site\": 678, \"_stat_site_order\": 676}, {\"site\": 679, \"_stat_site_order\": 677}, {\"site\": 680, \"_stat_site_order\": 678}, {\"site\": 681, \"_stat_site_order\": 679}, {\"site\": 682, \"_stat_site_order\": 680}, {\"site\": 683, \"_stat_site_order\": 681}, {\"site\": 684, \"_stat_site_order\": 682}, {\"site\": 685, \"_stat_site_order\": 683}, {\"site\": 686, \"_stat_site_order\": 684}, {\"site\": 687, \"_stat_site_order\": 685}, {\"site\": 688, \"_stat_site_order\": 686}, {\"site\": 689, \"_stat_site_order\": 687}, {\"site\": 690, \"_stat_site_order\": 688}, {\"site\": 691, \"_stat_site_order\": 689}, {\"site\": 693, \"_stat_site_order\": 690}, {\"site\": 694, \"_stat_site_order\": 691}, {\"site\": 695, \"_stat_site_order\": 692}, {\"site\": 696, \"_stat_site_order\": 693}, {\"site\": 697, \"_stat_site_order\": 694}, {\"site\": 698, \"_stat_site_order\": 695}, {\"site\": 699, \"_stat_site_order\": 696}, {\"site\": 700, \"_stat_site_order\": 697}, {\"site\": 701, \"_stat_site_order\": 698}, {\"site\": 702, \"_stat_site_order\": 699}, {\"site\": 703, \"_stat_site_order\": 700}, {\"site\": 704, \"_stat_site_order\": 701}, {\"site\": 705, \"_stat_site_order\": 702}, {\"site\": 706, \"_stat_site_order\": 703}, {\"site\": 707, \"_stat_site_order\": 704}, {\"site\": 708, \"_stat_site_order\": 705}, {\"site\": 709, \"_stat_site_order\": 706}, {\"site\": 710, \"_stat_site_order\": 707}, {\"site\": 711, \"_stat_site_order\": 708}, {\"site\": 712, \"_stat_site_order\": 709}, {\"site\": 713, \"_stat_site_order\": 710}, {\"site\": 714, \"_stat_site_order\": 711}, {\"site\": 715, \"_stat_site_order\": 712}, {\"site\": 716, \"_stat_site_order\": 713}, {\"site\": 717, \"_stat_site_order\": 714}, {\"site\": 718, \"_stat_site_order\": 715}, {\"site\": 719, \"_stat_site_order\": 716}, {\"site\": 720, \"_stat_site_order\": 717}, {\"site\": 721, \"_stat_site_order\": 718}, {\"site\": 722, \"_stat_site_order\": 719}, {\"site\": 723, \"_stat_site_order\": 720}, {\"site\": 724, \"_stat_site_order\": 721}, {\"site\": 725, \"_stat_site_order\": 722}, {\"site\": 726, \"_stat_site_order\": 723}, {\"site\": 727, \"_stat_site_order\": 724}, {\"site\": 728, \"_stat_site_order\": 725}, {\"site\": 729, \"_stat_site_order\": 726}, {\"site\": 730, \"_stat_site_order\": 727}, {\"site\": 731, \"_stat_site_order\": 728}, {\"site\": 732, \"_stat_site_order\": 729}, {\"site\": 733, \"_stat_site_order\": 730}, {\"site\": 734, \"_stat_site_order\": 731}, {\"site\": 735, \"_stat_site_order\": 732}, {\"site\": 736, \"_stat_site_order\": 733}, {\"site\": 737, \"_stat_site_order\": 734}, {\"site\": 738, \"_stat_site_order\": 735}, {\"site\": 739, \"_stat_site_order\": 736}, {\"site\": 740, \"_stat_site_order\": 737}, {\"site\": 741, \"_stat_site_order\": 738}, {\"site\": 742, \"_stat_site_order\": 739}, {\"site\": 743, \"_stat_site_order\": 740}, {\"site\": 744, \"_stat_site_order\": 741}, {\"site\": 745, \"_stat_site_order\": 742}, {\"site\": 746, \"_stat_site_order\": 743}, {\"site\": 747, \"_stat_site_order\": 744}, {\"site\": 748, \"_stat_site_order\": 745}, {\"site\": 749, \"_stat_site_order\": 746}, {\"site\": 750, \"_stat_site_order\": 747}, {\"site\": 751, \"_stat_site_order\": 748}, {\"site\": 752, \"_stat_site_order\": 749}, {\"site\": 753, \"_stat_site_order\": 750}, {\"site\": 754, \"_stat_site_order\": 751}, {\"site\": 755, \"_stat_site_order\": 752}, {\"site\": 756, \"_stat_site_order\": 753}, {\"site\": 757, \"_stat_site_order\": 754}, {\"site\": 758, \"_stat_site_order\": 755}, {\"site\": 759, \"_stat_site_order\": 756}, {\"site\": 760, \"_stat_site_order\": 757}, {\"site\": 761, \"_stat_site_order\": 758}, {\"site\": 762, \"_stat_site_order\": 759}, {\"site\": 763, \"_stat_site_order\": 760}, {\"site\": 764, \"_stat_site_order\": 761}, {\"site\": 765, \"_stat_site_order\": 762}, {\"site\": 766, \"_stat_site_order\": 763}, {\"site\": 767, \"_stat_site_order\": 764}, {\"site\": 768, \"_stat_site_order\": 765}, {\"site\": 769, \"_stat_site_order\": 766}, {\"site\": 770, \"_stat_site_order\": 767}, {\"site\": 771, \"_stat_site_order\": 768}, {\"site\": 772, \"_stat_site_order\": 769}, {\"site\": 773, \"_stat_site_order\": 770}, {\"site\": 774, \"_stat_site_order\": 771}, {\"site\": 775, \"_stat_site_order\": 772}, {\"site\": 776, \"_stat_site_order\": 773}, {\"site\": 777, \"_stat_site_order\": 774}, {\"site\": 778, \"_stat_site_order\": 775}, {\"site\": 779, \"_stat_site_order\": 776}, {\"site\": 780, \"_stat_site_order\": 777}, {\"site\": 781, \"_stat_site_order\": 778}, {\"site\": 782, \"_stat_site_order\": 779}, {\"site\": 783, \"_stat_site_order\": 780}, {\"site\": 784, \"_stat_site_order\": 781}, {\"site\": 785, \"_stat_site_order\": 782}, {\"site\": 786, \"_stat_site_order\": 783}, {\"site\": 787, \"_stat_site_order\": 784}, {\"site\": 788, \"_stat_site_order\": 785}, {\"site\": 789, \"_stat_site_order\": 786}, {\"site\": 790, \"_stat_site_order\": 787}, {\"site\": 791, \"_stat_site_order\": 788}, {\"site\": 792, \"_stat_site_order\": 789}, {\"site\": 793, \"_stat_site_order\": 790}, {\"site\": 794, \"_stat_site_order\": 791}, {\"site\": 795, \"_stat_site_order\": 792}, {\"site\": 796, \"_stat_site_order\": 793}, {\"site\": 797, \"_stat_site_order\": 794}, {\"site\": 798, \"_stat_site_order\": 795}, {\"site\": 799, \"_stat_site_order\": 796}, {\"site\": 800, \"_stat_site_order\": 797}, {\"site\": 801, \"_stat_site_order\": 798}, {\"site\": 802, \"_stat_site_order\": 799}, {\"site\": 803, \"_stat_site_order\": 800}, {\"site\": 804, \"_stat_site_order\": 801}, {\"site\": 805, \"_stat_site_order\": 802}, {\"site\": 806, \"_stat_site_order\": 803}, {\"site\": 807, \"_stat_site_order\": 804}, {\"site\": 808, \"_stat_site_order\": 805}, {\"site\": 809, \"_stat_site_order\": 806}, {\"site\": 810, \"_stat_site_order\": 807}, {\"site\": 811, \"_stat_site_order\": 808}, {\"site\": 812, \"_stat_site_order\": 809}, {\"site\": 813, \"_stat_site_order\": 810}, {\"site\": 814, \"_stat_site_order\": 811}, {\"site\": 815, \"_stat_site_order\": 812}, {\"site\": 816, \"_stat_site_order\": 813}, {\"site\": 817, \"_stat_site_order\": 814}, {\"site\": 818, \"_stat_site_order\": 815}, {\"site\": 819, \"_stat_site_order\": 816}, {\"site\": 820, \"_stat_site_order\": 817}, {\"site\": 821, \"_stat_site_order\": 818}, {\"site\": 822, \"_stat_site_order\": 819}, {\"site\": 823, \"_stat_site_order\": 820}, {\"site\": 824, \"_stat_site_order\": 821}, {\"site\": 825, \"_stat_site_order\": 822}, {\"site\": 826, \"_stat_site_order\": 823}, {\"site\": 827, \"_stat_site_order\": 824}, {\"site\": 828, \"_stat_site_order\": 825}, {\"site\": 829, \"_stat_site_order\": 826}, {\"site\": 830, \"_stat_site_order\": 827}, {\"site\": 831, \"_stat_site_order\": 828}, {\"site\": 832, \"_stat_site_order\": 829}, {\"site\": 833, \"_stat_site_order\": 830}, {\"site\": 834, \"_stat_site_order\": 831}, {\"site\": 835, \"_stat_site_order\": 832}, {\"site\": 836, \"_stat_site_order\": 833}, {\"site\": 837, \"_stat_site_order\": 834}, {\"site\": 838, \"_stat_site_order\": 835}, {\"site\": 839, \"_stat_site_order\": 836}, {\"site\": 840, \"_stat_site_order\": 837}, {\"site\": 841, \"_stat_site_order\": 838}, {\"site\": 842, \"_stat_site_order\": 839}, {\"site\": 843, \"_stat_site_order\": 840}, {\"site\": 844, \"_stat_site_order\": 841}, {\"site\": 845, \"_stat_site_order\": 842}, {\"site\": 846, \"_stat_site_order\": 843}, {\"site\": 847, \"_stat_site_order\": 844}, {\"site\": 848, \"_stat_site_order\": 845}, {\"site\": 849, \"_stat_site_order\": 846}, {\"site\": 850, \"_stat_site_order\": 847}, {\"site\": 851, \"_stat_site_order\": 848}, {\"site\": 852, \"_stat_site_order\": 849}, {\"site\": 853, \"_stat_site_order\": 850}, {\"site\": 854, \"_stat_site_order\": 851}, {\"site\": 855, \"_stat_site_order\": 852}, {\"site\": 856, \"_stat_site_order\": 853}, {\"site\": 857, \"_stat_site_order\": 854}, {\"site\": 858, \"_stat_site_order\": 855}, {\"site\": 859, \"_stat_site_order\": 856}, {\"site\": 860, \"_stat_site_order\": 857}, {\"site\": 861, \"_stat_site_order\": 858}, {\"site\": 862, \"_stat_site_order\": 859}, {\"site\": 863, \"_stat_site_order\": 860}, {\"site\": 864, \"_stat_site_order\": 861}, {\"site\": 865, \"_stat_site_order\": 862}, {\"site\": 866, \"_stat_site_order\": 863}, {\"site\": 867, \"_stat_site_order\": 864}, {\"site\": 868, \"_stat_site_order\": 865}, {\"site\": 869, \"_stat_site_order\": 866}, {\"site\": 870, \"_stat_site_order\": 867}, {\"site\": 871, \"_stat_site_order\": 868}, {\"site\": 872, \"_stat_site_order\": 869}, {\"site\": 873, \"_stat_site_order\": 870}, {\"site\": 874, \"_stat_site_order\": 871}, {\"site\": 875, \"_stat_site_order\": 872}, {\"site\": 876, \"_stat_site_order\": 873}, {\"site\": 877, \"_stat_site_order\": 874}, {\"site\": 878, \"_stat_site_order\": 875}, {\"site\": 879, \"_stat_site_order\": 876}, {\"site\": 880, \"_stat_site_order\": 877}, {\"site\": 881, \"_stat_site_order\": 878}, {\"site\": 882, \"_stat_site_order\": 879}, {\"site\": 883, \"_stat_site_order\": 880}, {\"site\": 884, \"_stat_site_order\": 881}, {\"site\": 885, \"_stat_site_order\": 882}, {\"site\": 886, \"_stat_site_order\": 883}, {\"site\": 887, \"_stat_site_order\": 884}, {\"site\": 888, \"_stat_site_order\": 885}, {\"site\": 889, \"_stat_site_order\": 886}, {\"site\": 890, \"_stat_site_order\": 887}, {\"site\": 891, \"_stat_site_order\": 888}, {\"site\": 892, \"_stat_site_order\": 889}, {\"site\": 893, \"_stat_site_order\": 890}, {\"site\": 894, \"_stat_site_order\": 891}, {\"site\": 895, \"_stat_site_order\": 892}, {\"site\": 896, \"_stat_site_order\": 893}, {\"site\": 897, \"_stat_site_order\": 894}, {\"site\": 898, \"_stat_site_order\": 895}, {\"site\": 899, \"_stat_site_order\": 896}, {\"site\": 900, \"_stat_site_order\": 897}, {\"site\": 901, \"_stat_site_order\": 898}, {\"site\": 902, \"_stat_site_order\": 899}, {\"site\": 903, \"_stat_site_order\": 900}, {\"site\": 904, \"_stat_site_order\": 901}, {\"site\": 905, \"_stat_site_order\": 902}, {\"site\": 906, \"_stat_site_order\": 903}, {\"site\": 907, \"_stat_site_order\": 904}, {\"site\": 908, \"_stat_site_order\": 905}, {\"site\": 909, \"_stat_site_order\": 906}, {\"site\": 910, \"_stat_site_order\": 907}, {\"site\": 911, \"_stat_site_order\": 908}, {\"site\": 912, \"_stat_site_order\": 909}, {\"site\": 913, \"_stat_site_order\": 910}, {\"site\": 914, \"_stat_site_order\": 911}, {\"site\": 915, \"_stat_site_order\": 912}, {\"site\": 916, \"_stat_site_order\": 913}, {\"site\": 917, \"_stat_site_order\": 914}, {\"site\": 918, \"_stat_site_order\": 915}, {\"site\": 919, \"_stat_site_order\": 916}, {\"site\": 920, \"_stat_site_order\": 917}, {\"site\": 921, \"_stat_site_order\": 918}, {\"site\": 922, \"_stat_site_order\": 919}, {\"site\": 923, \"_stat_site_order\": 920}, {\"site\": 924, \"_stat_site_order\": 921}, {\"site\": 925, \"_stat_site_order\": 922}, {\"site\": 926, \"_stat_site_order\": 923}, {\"site\": 927, \"_stat_site_order\": 924}, {\"site\": 928, \"_stat_site_order\": 925}, {\"site\": 929, \"_stat_site_order\": 926}, {\"site\": 930, \"_stat_site_order\": 927}, {\"site\": 931, \"_stat_site_order\": 928}, {\"site\": 932, \"_stat_site_order\": 929}, {\"site\": 933, \"_stat_site_order\": 930}, {\"site\": 934, \"_stat_site_order\": 931}, {\"site\": 935, \"_stat_site_order\": 932}, {\"site\": 936, \"_stat_site_order\": 933}, {\"site\": 937, \"_stat_site_order\": 934}, {\"site\": 938, \"_stat_site_order\": 935}, {\"site\": 939, \"_stat_site_order\": 936}, {\"site\": 940, \"_stat_site_order\": 937}, {\"site\": 941, \"_stat_site_order\": 938}, {\"site\": 942, \"_stat_site_order\": 939}, {\"site\": 943, \"_stat_site_order\": 940}, {\"site\": 944, \"_stat_site_order\": 941}, {\"site\": 945, \"_stat_site_order\": 942}, {\"site\": 946, \"_stat_site_order\": 943}, {\"site\": 947, \"_stat_site_order\": 944}, {\"site\": 948, \"_stat_site_order\": 945}, {\"site\": 949, \"_stat_site_order\": 946}, {\"site\": 950, \"_stat_site_order\": 947}, {\"site\": 951, \"_stat_site_order\": 948}, {\"site\": 952, \"_stat_site_order\": 949}, {\"site\": 953, \"_stat_site_order\": 950}, {\"site\": 954, \"_stat_site_order\": 951}, {\"site\": 955, \"_stat_site_order\": 952}, {\"site\": 956, \"_stat_site_order\": 953}, {\"site\": 957, \"_stat_site_order\": 954}, {\"site\": 958, \"_stat_site_order\": 955}, {\"site\": 959, \"_stat_site_order\": 956}, {\"site\": 960, \"_stat_site_order\": 957}, {\"site\": 961, \"_stat_site_order\": 958}, {\"site\": 962, \"_stat_site_order\": 959}, {\"site\": 963, \"_stat_site_order\": 960}, {\"site\": 964, \"_stat_site_order\": 961}, {\"site\": 965, \"_stat_site_order\": 962}, {\"site\": 966, \"_stat_site_order\": 963}, {\"site\": 967, \"_stat_site_order\": 964}, {\"site\": 968, \"_stat_site_order\": 965}, {\"site\": 969, \"_stat_site_order\": 966}, {\"site\": 970, \"_stat_site_order\": 967}, {\"site\": 971, \"_stat_site_order\": 968}, {\"site\": 972, \"_stat_site_order\": 969}, {\"site\": 973, \"_stat_site_order\": 970}, {\"site\": 974, \"_stat_site_order\": 971}, {\"site\": 975, \"_stat_site_order\": 972}, {\"site\": 976, \"_stat_site_order\": 973}, {\"site\": 977, \"_stat_site_order\": 974}, {\"site\": 978, \"_stat_site_order\": 975}, {\"site\": 979, \"_stat_site_order\": 976}, {\"site\": 980, \"_stat_site_order\": 977}, {\"site\": 981, \"_stat_site_order\": 978}, {\"site\": 982, \"_stat_site_order\": 979}, {\"site\": 983, \"_stat_site_order\": 980}, {\"site\": 984, \"_stat_site_order\": 981}, {\"site\": 985, \"_stat_site_order\": 982}, {\"site\": 986, \"_stat_site_order\": 983}, {\"site\": 987, \"_stat_site_order\": 984}, {\"site\": 988, \"_stat_site_order\": 985}, {\"site\": 989, \"_stat_site_order\": 986}, {\"site\": 990, \"_stat_site_order\": 987}, {\"site\": 991, \"_stat_site_order\": 988}, {\"site\": 992, \"_stat_site_order\": 989}, {\"site\": 993, \"_stat_site_order\": 990}, {\"site\": 994, \"_stat_site_order\": 991}, {\"site\": 995, \"_stat_site_order\": 992}, {\"site\": 996, \"_stat_site_order\": 993}, {\"site\": 997, \"_stat_site_order\": 994}, {\"site\": 998, \"_stat_site_order\": 995}, {\"site\": 999, \"_stat_site_order\": 996}, {\"site\": 1000, \"_stat_site_order\": 997}, {\"site\": 1001, \"_stat_site_order\": 998}, {\"site\": 1002, \"_stat_site_order\": 999}, {\"site\": 1003, \"_stat_site_order\": 1000}, {\"site\": 1004, \"_stat_site_order\": 1001}, {\"site\": 1005, \"_stat_site_order\": 1002}, {\"site\": 1006, \"_stat_site_order\": 1003}, {\"site\": 1007, \"_stat_site_order\": 1004}, {\"site\": 1008, \"_stat_site_order\": 1005}, {\"site\": 1009, \"_stat_site_order\": 1006}, {\"site\": 1010, \"_stat_site_order\": 1007}, {\"site\": 1011, \"_stat_site_order\": 1008}, {\"site\": 1012, \"_stat_site_order\": 1009}, {\"site\": 1013, \"_stat_site_order\": 1010}, {\"site\": 1014, \"_stat_site_order\": 1011}, {\"site\": 1015, \"_stat_site_order\": 1012}, {\"site\": 1016, \"_stat_site_order\": 1013}, {\"site\": 1017, \"_stat_site_order\": 1014}, {\"site\": 1018, \"_stat_site_order\": 1015}, {\"site\": 1019, \"_stat_site_order\": 1016}, {\"site\": 1020, \"_stat_site_order\": 1017}, {\"site\": 1021, \"_stat_site_order\": 1018}, {\"site\": 1022, \"_stat_site_order\": 1019}, {\"site\": 1023, \"_stat_site_order\": 1020}, {\"site\": 1024, \"_stat_site_order\": 1021}, {\"site\": 1025, \"_stat_site_order\": 1022}, {\"site\": 1026, \"_stat_site_order\": 1023}, {\"site\": 1027, \"_stat_site_order\": 1024}, {\"site\": 1028, \"_stat_site_order\": 1025}, {\"site\": 1029, \"_stat_site_order\": 1026}, {\"site\": 1030, \"_stat_site_order\": 1027}, {\"site\": 1031, \"_stat_site_order\": 1028}, {\"site\": 1032, \"_stat_site_order\": 1029}, {\"site\": 1033, \"_stat_site_order\": 1030}, {\"site\": 1034, \"_stat_site_order\": 1031}, {\"site\": 1035, \"_stat_site_order\": 1032}, {\"site\": 1036, \"_stat_site_order\": 1033}, {\"site\": 1037, \"_stat_site_order\": 1034}, {\"site\": 1038, \"_stat_site_order\": 1035}, {\"site\": 1039, \"_stat_site_order\": 1036}, {\"site\": 1040, \"_stat_site_order\": 1037}, {\"site\": 1041, \"_stat_site_order\": 1038}, {\"site\": 1042, \"_stat_site_order\": 1039}, {\"site\": 1043, \"_stat_site_order\": 1040}, {\"site\": 1044, \"_stat_site_order\": 1041}, {\"site\": 1045, \"_stat_site_order\": 1042}, {\"site\": 1046, \"_stat_site_order\": 1043}, {\"site\": 1047, \"_stat_site_order\": 1044}, {\"site\": 1048, \"_stat_site_order\": 1045}, {\"site\": 1049, \"_stat_site_order\": 1046}, {\"site\": 1051, \"_stat_site_order\": 1047}, {\"site\": 1052, \"_stat_site_order\": 1048}, {\"site\": 1053, \"_stat_site_order\": 1049}, {\"site\": 1054, \"_stat_site_order\": 1050}, {\"site\": 1055, \"_stat_site_order\": 1051}, {\"site\": 1056, \"_stat_site_order\": 1052}, {\"site\": 1057, \"_stat_site_order\": 1053}, {\"site\": 1058, \"_stat_site_order\": 1054}, {\"site\": 1059, \"_stat_site_order\": 1055}, {\"site\": 1060, \"_stat_site_order\": 1056}, {\"site\": 1061, \"_stat_site_order\": 1057}, {\"site\": 1062, \"_stat_site_order\": 1058}, {\"site\": 1063, \"_stat_site_order\": 1059}, {\"site\": 1064, \"_stat_site_order\": 1060}, {\"site\": 1065, \"_stat_site_order\": 1061}, {\"site\": 1066, \"_stat_site_order\": 1062}, {\"site\": 1067, \"_stat_site_order\": 1063}, {\"site\": 1068, \"_stat_site_order\": 1064}, {\"site\": 1069, \"_stat_site_order\": 1065}, {\"site\": 1070, \"_stat_site_order\": 1066}, {\"site\": 1071, \"_stat_site_order\": 1067}, {\"site\": 1072, \"_stat_site_order\": 1068}, {\"site\": 1073, \"_stat_site_order\": 1069}, {\"site\": 1074, \"_stat_site_order\": 1070}, {\"site\": 1075, \"_stat_site_order\": 1071}, {\"site\": 1076, \"_stat_site_order\": 1072}, {\"site\": 1077, \"_stat_site_order\": 1073}, {\"site\": 1078, \"_stat_site_order\": 1074}, {\"site\": 1079, \"_stat_site_order\": 1075}, {\"site\": 1080, \"_stat_site_order\": 1076}, {\"site\": 1081, \"_stat_site_order\": 1077}, {\"site\": 1082, \"_stat_site_order\": 1078}, {\"site\": 1083, \"_stat_site_order\": 1079}, {\"site\": 1084, \"_stat_site_order\": 1080}, {\"site\": 1085, \"_stat_site_order\": 1081}, {\"site\": 1086, \"_stat_site_order\": 1082}, {\"site\": 1087, \"_stat_site_order\": 1083}, {\"site\": 1088, \"_stat_site_order\": 1084}, {\"site\": 1089, \"_stat_site_order\": 1085}, {\"site\": 1090, \"_stat_site_order\": 1086}, {\"site\": 1091, \"_stat_site_order\": 1087}, {\"site\": 1092, \"_stat_site_order\": 1088}, {\"site\": 1093, \"_stat_site_order\": 1089}, {\"site\": 1094, \"_stat_site_order\": 1090}, {\"site\": 1095, \"_stat_site_order\": 1091}, {\"site\": 1096, \"_stat_site_order\": 1092}, {\"site\": 1097, \"_stat_site_order\": 1093}, {\"site\": 1098, \"_stat_site_order\": 1094}, {\"site\": 1099, \"_stat_site_order\": 1095}, {\"site\": 1100, \"_stat_site_order\": 1096}, {\"site\": 1101, \"_stat_site_order\": 1097}, {\"site\": 1102, \"_stat_site_order\": 1098}, {\"site\": 1103, \"_stat_site_order\": 1099}, {\"site\": 1104, \"_stat_site_order\": 1100}, {\"site\": 1105, \"_stat_site_order\": 1101}, {\"site\": 1106, \"_stat_site_order\": 1102}, {\"site\": 1107, \"_stat_site_order\": 1103}, {\"site\": 1108, \"_stat_site_order\": 1104}, {\"site\": 1109, \"_stat_site_order\": 1105}, {\"site\": 1110, \"_stat_site_order\": 1106}, {\"site\": 1111, \"_stat_site_order\": 1107}, {\"site\": 1112, \"_stat_site_order\": 1108}, {\"site\": 1113, \"_stat_site_order\": 1109}, {\"site\": 1114, \"_stat_site_order\": 1110}, {\"site\": 1115, \"_stat_site_order\": 1111}, {\"site\": 1116, \"_stat_site_order\": 1112}, {\"site\": 1117, \"_stat_site_order\": 1113}, {\"site\": 1118, \"_stat_site_order\": 1114}, {\"site\": 1119, \"_stat_site_order\": 1115}, {\"site\": 1120, \"_stat_site_order\": 1116}, {\"site\": 1121, \"_stat_site_order\": 1117}, {\"site\": 1122, \"_stat_site_order\": 1118}, {\"site\": 1123, \"_stat_site_order\": 1119}, {\"site\": 1124, \"_stat_site_order\": 1120}, {\"site\": 1125, \"_stat_site_order\": 1121}, {\"site\": 1126, \"_stat_site_order\": 1122}, {\"site\": 1127, \"_stat_site_order\": 1123}, {\"site\": 1128, \"_stat_site_order\": 1124}, {\"site\": 1129, \"_stat_site_order\": 1125}, {\"site\": 1130, \"_stat_site_order\": 1126}, {\"site\": 1131, \"_stat_site_order\": 1127}, {\"site\": 1132, \"_stat_site_order\": 1128}, {\"site\": 1133, \"_stat_site_order\": 1129}, {\"site\": 1134, \"_stat_site_order\": 1130}, {\"site\": 1135, \"_stat_site_order\": 1131}, {\"site\": 1136, \"_stat_site_order\": 1132}, {\"site\": 1137, \"_stat_site_order\": 1133}, {\"site\": 1138, \"_stat_site_order\": 1134}, {\"site\": 1139, \"_stat_site_order\": 1135}, {\"site\": 1140, \"_stat_site_order\": 1136}, {\"site\": 1141, \"_stat_site_order\": 1137}, {\"site\": 1142, \"_stat_site_order\": 1138}, {\"site\": 1143, \"_stat_site_order\": 1139}, {\"site\": 1144, \"_stat_site_order\": 1140}, {\"site\": 1145, \"_stat_site_order\": 1141}, {\"site\": 1146, \"_stat_site_order\": 1142}, {\"site\": 1147, \"_stat_site_order\": 1143}, {\"site\": 1148, \"_stat_site_order\": 1144}, {\"site\": 1149, \"_stat_site_order\": 1145}, {\"site\": 1150, \"_stat_site_order\": 1146}, {\"site\": 1151, \"_stat_site_order\": 1147}, {\"site\": 1152, \"_stat_site_order\": 1148}, {\"site\": 1153, \"_stat_site_order\": 1149}, {\"site\": 1154, \"_stat_site_order\": 1150}, {\"site\": 1155, \"_stat_site_order\": 1151}, {\"site\": 1156, \"_stat_site_order\": 1152}, {\"site\": 1157, \"_stat_site_order\": 1153}, {\"site\": 1158, \"_stat_site_order\": 1154}, {\"site\": 1159, \"_stat_site_order\": 1155}, {\"site\": 1160, \"_stat_site_order\": 1156}, {\"site\": 1161, \"_stat_site_order\": 1157}, {\"site\": 1162, \"_stat_site_order\": 1158}, {\"site\": 1163, \"_stat_site_order\": 1159}, {\"site\": 1164, \"_stat_site_order\": 1160}, {\"site\": 1165, \"_stat_site_order\": 1161}, {\"site\": 1166, \"_stat_site_order\": 1162}, {\"site\": 1167, \"_stat_site_order\": 1163}, {\"site\": 1168, \"_stat_site_order\": 1164}, {\"site\": 1169, \"_stat_site_order\": 1165}, {\"site\": 1170, \"_stat_site_order\": 1166}, {\"site\": 1171, \"_stat_site_order\": 1167}, {\"site\": 1172, \"_stat_site_order\": 1168}, {\"site\": 1173, \"_stat_site_order\": 1169}, {\"site\": 1174, \"_stat_site_order\": 1170}, {\"site\": 1175, \"_stat_site_order\": 1171}, {\"site\": 1176, \"_stat_site_order\": 1172}, {\"site\": 1177, \"_stat_site_order\": 1173}, {\"site\": 1178, \"_stat_site_order\": 1174}, {\"site\": 1179, \"_stat_site_order\": 1175}, {\"site\": 1180, \"_stat_site_order\": 1176}, {\"site\": 1181, \"_stat_site_order\": 1177}, {\"site\": 1182, \"_stat_site_order\": 1178}, {\"site\": 1183, \"_stat_site_order\": 1179}, {\"site\": 1184, \"_stat_site_order\": 1180}, {\"site\": 1185, \"_stat_site_order\": 1181}, {\"site\": 1186, \"_stat_site_order\": 1182}, {\"site\": 1187, \"_stat_site_order\": 1183}, {\"site\": 1188, \"_stat_site_order\": 1184}, {\"site\": 1189, \"_stat_site_order\": 1185}, {\"site\": 1190, \"_stat_site_order\": 1186}, {\"site\": 1191, \"_stat_site_order\": 1187}, {\"site\": 1192, \"_stat_site_order\": 1188}, {\"site\": 1193, \"_stat_site_order\": 1189}, {\"site\": 1194, \"_stat_site_order\": 1190}, {\"site\": 1195, \"_stat_site_order\": 1191}, {\"site\": 1196, \"_stat_site_order\": 1192}, {\"site\": 1197, \"_stat_site_order\": 1193}, {\"site\": 1198, \"_stat_site_order\": 1194}, {\"site\": 1199, \"_stat_site_order\": 1195}, {\"site\": 1200, \"_stat_site_order\": 1196}, {\"site\": 1201, \"_stat_site_order\": 1197}, {\"site\": 1202, \"_stat_site_order\": 1198}, {\"site\": 1203, \"_stat_site_order\": 1199}, {\"site\": 1204, \"_stat_site_order\": 1200}, {\"site\": 1205, \"_stat_site_order\": 1201}, {\"site\": 1206, \"_stat_site_order\": 1202}, {\"site\": 1207, \"_stat_site_order\": 1203}, {\"site\": 1208, \"_stat_site_order\": 1204}, {\"site\": 1209, \"_stat_site_order\": 1205}, {\"site\": 1210, \"_stat_site_order\": 1206}, {\"site\": 1211, \"_stat_site_order\": 1207}, {\"site\": 1212, \"_stat_site_order\": 1208}, {\"site\": 1213, \"_stat_site_order\": 1209}, {\"site\": 1214, \"_stat_site_order\": 1210}, {\"site\": 1215, \"_stat_site_order\": 1211}, {\"site\": 1216, \"_stat_site_order\": 1212}, {\"site\": 1217, \"_stat_site_order\": 1213}, {\"site\": 1218, \"_stat_site_order\": 1214}, {\"site\": 1219, \"_stat_site_order\": 1215}, {\"site\": 1220, \"_stat_site_order\": 1216}, {\"site\": 1221, \"_stat_site_order\": 1217}, {\"site\": 1222, \"_stat_site_order\": 1218}, {\"site\": 1223, \"_stat_site_order\": 1219}, {\"site\": 1224, \"_stat_site_order\": 1220}, {\"site\": 1225, \"_stat_site_order\": 1221}, {\"site\": 1226, \"_stat_site_order\": 1222}, {\"site\": 1227, \"_stat_site_order\": 1223}, {\"site\": 1228, \"_stat_site_order\": 1224}, {\"site\": 1229, \"_stat_site_order\": 1225}, {\"site\": 1230, \"_stat_site_order\": 1226}, {\"site\": 1231, \"_stat_site_order\": 1227}, {\"site\": 1232, \"_stat_site_order\": 1228}, {\"site\": 1233, \"_stat_site_order\": 1229}, {\"site\": 1234, \"_stat_site_order\": 1230}, {\"site\": 1235, \"_stat_site_order\": 1231}, {\"site\": 1236, \"_stat_site_order\": 1232}, {\"site\": 1237, \"_stat_site_order\": 1233}, {\"site\": 1238, \"_stat_site_order\": 1234}, {\"site\": 1239, \"_stat_site_order\": 1235}, {\"site\": 1240, \"_stat_site_order\": 1236}, {\"site\": 1241, \"_stat_site_order\": 1237}, {\"site\": 1242, \"_stat_site_order\": 1238}, {\"site\": 1243, \"_stat_site_order\": 1239}, {\"site\": 1244, \"_stat_site_order\": 1240}, {\"site\": 1245, \"_stat_site_order\": 1241}, {\"site\": 1246, \"_stat_site_order\": 1242}, {\"site\": 1247, \"_stat_site_order\": 1243}, {\"site\": 1248, \"_stat_site_order\": 1244}, {\"site\": 1249, \"_stat_site_order\": 1245}, {\"site\": 1250, \"_stat_site_order\": 1246}], \"data-bba4f8a09147f0e0e12310f5961c26ef\": [{\"site\": 1, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004631142848387763, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": 0.0871504064795966, \"functional effect\": -2.2303, \"times_seen\": 1.0}, {\"site\": 1, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.008652568534920468, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": 0.08690781821849496, \"functional effect\": -2.4823, \"times_seen\": 2.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -7.926585615243922e-05, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08742581076981522, \"functional effect\": 0.0498, \"times_seen\": 2.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.014369229282163535, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08830577349481833, \"functional effect\": 0.2451, \"times_seen\": 14.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01369360207594228, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08660467673947705, \"functional effect\": 0.382, \"times_seen\": 14.0}, {\"site\": 2, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.034182079247545544, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08952686175194355, \"functional effect\": 0.3639, \"times_seen\": 4.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0028246601828262868, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08725960094031368, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.040070799324092105, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08503564641150986, \"functional effect\": 0.0936, \"times_seen\": 19.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.003444296538586203, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08722213105934898, \"functional effect\": -0.1408, \"times_seen\": 1.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.061939179887444094, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.0912660135117912, \"functional effect\": -0.263, \"times_seen\": 91.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.8124085724473906, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.1535404747089231, \"functional effect\": -0.0572, \"times_seen\": 62.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.24588264931060022, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.07373021105840853, \"functional effect\": -0.1162, \"times_seen\": 69.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.016950086500673752, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08640941113336198, \"functional effect\": -0.052, \"times_seen\": 40.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.01655602989066599, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08843972664579647, \"functional effect\": -0.1206, \"times_seen\": 11.0}, {\"site\": 3, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.007429727775876056, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.08788203418583126, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.09278663231834582, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.0932384595124944, \"functional effect\": 0.1365, \"times_seen\": 35.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03172770457208795, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.08552883159449372, \"functional effect\": 0.1702, \"times_seen\": 26.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.519134843461804, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.2505928557150874, \"functional effect\": -0.4127, \"times_seen\": 28.0}, {\"site\": 4, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.036085403749931515, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.08527087923018357, \"functional effect\": -0.3325, \"times_seen\": 10.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004700861417288782, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08714619501796612, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.021150513509086095, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08615819479860522, \"functional effect\": 0.3095, \"times_seen\": 61.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.13169952293597617, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.07980278045927128, \"functional effect\": 0.2806, \"times_seen\": 42.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0008720116323645653, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08737778440099711, \"functional effect\": -1.3074, \"times_seen\": 5.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.011034437750061332, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08810189030923721, \"functional effect\": -1.5861, \"times_seen\": 7.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.10258651713595918, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09387396219253702, \"functional effect\": 0.397, \"times_seen\": 54.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"G\", \"log2 fold change IC90\": -1.4755902188621743, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.031438847187823374, \"functional effect\": 0.1809, \"times_seen\": 40.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.13391673864898276, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09593486863775273, \"functional effect\": 0.2581, \"times_seen\": 53.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.01800779932286833, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08852876744139676, \"functional effect\": 0.3636, \"times_seen\": 60.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.011737975776278714, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08672215217383782, \"functional effect\": -2.9296, \"times_seen\": 1.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.428405745471543, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.06496815748986984, \"functional effect\": -0.2568, \"times_seen\": 44.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07647114271395931, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08291696975781623, \"functional effect\": -0.0041, \"times_seen\": 22.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.8129316270386332, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.04976760321218617, \"functional effect\": -1.1555, \"times_seen\": 115.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 1.5766575752733092, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.26078628818957417, \"functional effect\": -0.6278, \"times_seen\": 2.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.7245437631215523, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.14446842423957948, \"functional effect\": -0.369, \"times_seen\": 86.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.3099127856826518, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.10838185365832433, \"functional effect\": 0.0821, \"times_seen\": 97.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.1259157817101607, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08012335067427423, \"functional effect\": 0.2298, \"times_seen\": 85.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.054782253431030596, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09081438191611879, \"functional effect\": 0.2278, \"times_seen\": 57.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.11281514178783437, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09454188815193393, \"functional effect\": -0.1663, \"times_seen\": 27.0}, {\"site\": 5, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.016804820092678606, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08641811222152951, \"functional effect\": 0.3396, \"times_seen\": 31.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01912574428742707, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08859739500504596, \"functional effect\": 0.2169, \"times_seen\": 72.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.016038237011420063, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08646404311075244, \"functional effect\": 0.3016, \"times_seen\": 18.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.052750672755991504, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.09068658851812003, \"functional effect\": 0.3019, \"times_seen\": 54.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.012402942511107714, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08818550122828259, \"functional effect\": 0.374, \"times_seen\": 58.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0003202086718667068, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08741121110632083, \"functional effect\": 0.397, \"times_seen\": 44.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0943828934542228, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08189388003421752, \"functional effect\": 0.3992, \"times_seen\": 16.0}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 6, \"wildtype\": \"V\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.005227731668008297, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08711437515767813, \"functional effect\": 0.2707, \"times_seen\": 1.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.1169180841799793, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08062461978784276, \"functional effect\": -0.187, \"times_seen\": 57.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01834116028810831, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08632613370356776, \"functional effect\": -0.2303, \"times_seen\": 11.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.006456666399313967, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08704019988609284, \"functional effect\": -0.2428, \"times_seen\": 1.0}, {\"site\": 7, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01669004433858537, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08844794234717995, \"functional effect\": -2.1974, \"times_seen\": 3.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -2.176681508343823, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.01933824708618436, \"functional effect\": -0.7435, \"times_seen\": 31.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.029918772089832697, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08563613973208221, \"functional effect\": 0.0972, \"times_seen\": 8.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.015744318722366233, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08648166010657357, \"functional effect\": -2.4719, \"times_seen\": 5.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.018387462974074505, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08632336314734913, \"functional effect\": -0.6371, \"times_seen\": 10.0}, {\"site\": 8, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.028794578710592923, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08570289611319426, \"functional effect\": -0.2813, \"times_seen\": 19.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"-\", \"log2 fold change IC90\": -7.400321560410228e-05, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.08742612968091067, \"functional effect\": 0.2833, \"times_seen\": 1.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.3327776010517015, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.06942046048832388, \"functional effect\": 0.1735, \"times_seen\": 93.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.13973456914746002, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.09632251791204466, \"functional effect\": 0.1042, \"times_seen\": 17.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.036975817616677606, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.08970039596951192, \"functional effect\": 0.0833, \"times_seen\": 14.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.016139588660776374, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.08645796908587462, \"functional effect\": 0.2579, \"times_seen\": 50.0}, {\"site\": 9, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.48313028434217414, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.12220816902511383, \"functional effect\": 0.0953, \"times_seen\": 78.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.10325261329214294, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.09391731405883884, \"functional effect\": 0.4444, \"times_seen\": 57.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.021538583135678913, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08613502227699918, \"functional effect\": 0.2022, \"times_seen\": 9.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.05259100472195064, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.0843008706588829, \"functional effect\": -0.8768, \"times_seen\": 11.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0013639923553799866, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08751331446976837, \"functional effect\": 0.1603, \"times_seen\": 3.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.011273163372955747, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08675009711373101, \"functional effect\": -0.1532, \"times_seen\": 6.0}, {\"site\": 10, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05826501810629925, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08396997266607413, \"functional effect\": 0.3729, \"times_seen\": 39.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.004559960600692805, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.08770739554034387, \"functional effect\": -0.2745, \"times_seen\": 8.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0024013053293545287, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.08728521078528013, \"functional effect\": -0.1303, \"times_seen\": 5.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.045621076843183554, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.08470912922544836, \"functional effect\": 0.3549, \"times_seen\": 45.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04936140311064159, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.09047379195381491, \"functional effect\": 0.4444, \"times_seen\": 32.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.4731544102665913, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.12136604510507149, \"functional effect\": 0.2851, \"times_seen\": 57.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.06554471208537249, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.09149438754402406, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.1219740844616355, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.0803425611212567, \"functional effect\": 0.0913, \"times_seen\": 1.0}, {\"site\": 11, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.027707803910172614, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08576747998909075, \"functional effect\": -0.0764, \"times_seen\": 32.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.008950466340972463, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08797471909646971, \"functional effect\": -0.2192, \"times_seen\": 47.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.013462461888582621, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08661855314737708, \"functional effect\": 0.0764, \"times_seen\": 3.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02743537635176426, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08578367719689657, \"functional effect\": 0.1186, \"times_seen\": 6.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.05481319861178117, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.09081632986597875, \"functional effect\": -0.1239, \"times_seen\": 73.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.006466928680313583, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08703958074775293, \"functional effect\": 0.103, \"times_seen\": 8.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.025978862471809288, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08901925324904487, \"functional effect\": -0.2061, \"times_seen\": 7.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02539380608896705, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0889831605738815, \"functional effect\": 0.1301, \"times_seen\": 9.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.013611096863156983, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08660962965149148, \"functional effect\": 0.0061, \"times_seen\": 4.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.3607215544840266, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.11226685016204438, \"functional effect\": 0.0117, \"times_seen\": 36.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.019391249872135124, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0862633226529663, \"functional effect\": -0.0662, \"times_seen\": 6.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.001885313481460807, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0875449433187283, \"functional effect\": -0.2492, \"times_seen\": 12.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.02815704010892446, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08915375582206822, \"functional effect\": -0.0798, \"times_seen\": 63.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010709349637140573, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0867840061891268, \"functional effect\": -0.5121, \"times_seen\": 3.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.04002342993130989, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08989008330369545, \"functional effect\": -0.2823, \"times_seen\": 22.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.023162696643476182, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08603811036112621, \"functional effect\": 0.0059, \"times_seen\": 44.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.050755098201544335, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08440821630790686, \"functional effect\": -0.3056, \"times_seen\": 13.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.005735373975429727, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0870837275421446, \"functional effect\": 0.0421, \"times_seen\": 1.0}, {\"site\": 12, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.05449126374233116, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0907960666221004, \"functional effect\": -0.2352, \"times_seen\": 47.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0041790517012426495, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08717772070752455, \"functional effect\": -0.0454, \"times_seen\": 1.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.12025982994934202, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08043808335743509, \"functional effect\": 0.401, \"times_seen\": 15.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.037543586576103266, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08973570427920984, \"functional effect\": 0.0129, \"times_seen\": 15.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.009885497246160235, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08683357843213921, \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.006895174372162958, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08784947779860672, \"functional effect\": 0.2161, \"times_seen\": 5.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.01856295287819735, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08631286338338447, \"functional effect\": -0.1084, \"times_seen\": 6.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.058877432412246106, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08393433554391058, \"functional effect\": -0.029, \"times_seen\": 40.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.005426593485868022, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08776009756361303, \"functional effect\": 0.0421, \"times_seen\": 20.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.028623258385656276, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08571307395356396, \"functional effect\": -0.1889, \"times_seen\": 3.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.2219734877842288, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.10197276796646408, \"functional effect\": 0.289, \"times_seen\": 20.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.02872788688723082, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08570685801391435, \"functional effect\": 0.1308, \"times_seen\": 7.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04124746756318318, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08996638184990165, \"functional effect\": 0.005, \"times_seen\": 24.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004786956963820191, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.0871409945596536, \"functional effect\": 0.3762, \"times_seen\": 3.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.009045660390504697, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08798052416672429, \"functional effect\": -0.2887, \"times_seen\": 2.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.013680872440704834, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08826364998122344, \"functional effect\": -0.5151, \"times_seen\": 16.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.016711656943889208, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08642369291819349, \"functional effect\": 0.2847, \"times_seen\": 6.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.022185801284119976, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.088785515709054, \"functional effect\": 0.0634, \"times_seen\": 23.0}, {\"site\": 13, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.012775303411873969, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08665981956093333, \"functional effect\": -0.2438, \"times_seen\": 8.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.011927228665443525, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08815642776020607, \"functional effect\": 0.418, \"times_seen\": 11.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.09832860304811687, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08167020975819408, \"functional effect\": 0.4201, \"times_seen\": 72.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.001293945767182552, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08750906557439188, \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.019723272098505953, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08863409740617696, \"functional effect\": 0.4294, \"times_seen\": 18.0}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 14, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.012952460660526223, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08821909721515651, \"functional effect\": -0.1732, \"times_seen\": 45.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.011678677204661007, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.0881412412371324, \"functional effect\": 0.0431, \"times_seen\": 23.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -1.645800640105877, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.027940113783617992, \"functional effect\": 0.2209, \"times_seen\": 73.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.05139876470057304, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08437056550759202, \"functional effect\": -0.186, \"times_seen\": 6.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.4645019789958054, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.12064034171892381, \"functional effect\": 0.251, \"times_seen\": 11.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.007065623073517507, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08785985747938829, \"functional effect\": 0.1163, \"times_seen\": 16.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.004607767494247062, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08715181855079739, \"functional effect\": 0.1541, \"times_seen\": 1.0}, {\"site\": 15, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03479442111585939, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08956486887062576, \"functional effect\": 0.0628, \"times_seen\": 28.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.12887210926099968, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.07995933240728471, \"functional effect\": -0.136, \"times_seen\": 17.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.09642921062414393, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08177780417896352, \"functional effect\": -0.1663, \"times_seen\": 68.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.1202497214926686, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.080438646960765, \"functional effect\": 0.0322, \"times_seen\": 65.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.036623897348645525, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08967851779245153, \"functional effect\": 0.0386, \"times_seen\": 49.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.028495825752680396, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08572064528693321, \"functional effect\": -0.0772, \"times_seen\": 42.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.015016320450685185, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08652531062502661, \"functional effect\": 0.2404, \"times_seen\": 22.0}, {\"site\": 16, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0024605161698042053, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08728162851426126, \"functional effect\": 0.0501, \"times_seen\": 1.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.28859776396596576, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.10679234267006542, \"functional effect\": -0.376, \"times_seen\": 60.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0069537785232794466, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08785304643126583, \"functional effect\": -0.5785, \"times_seen\": 11.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.22553306489413313, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.10222467712332206, \"functional effect\": -0.4162, \"times_seen\": 36.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00030273802844823556, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08741226963865326, \"functional effect\": -0.511, \"times_seen\": 9.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06098892860530704, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08381158098009847, \"functional effect\": -0.554, \"times_seen\": 31.0}, {\"site\": 17, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.041843610924349406, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08493121713820388, \"functional effect\": -0.5979, \"times_seen\": 19.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0017054154728015963, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08732732331963798, \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004673708053536295, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.0871478352361235, \"functional effect\": 0.0466, \"times_seen\": 1.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.11362957794434826, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08080860667591011, \"functional effect\": -0.1471, \"times_seen\": 45.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.006382897560199423, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08781828946001818, \"functional effect\": -0.6401, \"times_seen\": 21.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.014276836004919856, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08656967240667889, \"functional effect\": -0.2457, \"times_seen\": 13.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02028483534096148, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08620990888076746, \"functional effect\": 0.0624, \"times_seen\": 26.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.2737122670668812, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.1056961412833709, \"functional effect\": -0.0948, \"times_seen\": 42.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.09458799813860103, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08188223819445604, \"functional effect\": -0.2994, \"times_seen\": 25.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.008094650514890235, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.0879225474123085, \"functional effect\": -0.2382, \"times_seen\": 24.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0010535030608295204, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08736679294333695, \"functional effect\": -0.1222, \"times_seen\": 25.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.049864098852805856, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08446036239027202, \"functional effect\": 0.2198, \"times_seen\": 55.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0072306680899129954, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08699351559628941, \"functional effect\": -0.0761, \"times_seen\": 38.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.015650613080590292, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08648727742861113, \"functional effect\": -0.3196, \"times_seen\": 9.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.6412102035980034, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.056058313134799316, \"functional effect\": -0.031, \"times_seen\": 147.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05161720619011402, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08435779174994673, \"functional effect\": -0.1973, \"times_seen\": 51.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.08658566897003016, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08233768389365502, \"functional effect\": -0.1738, \"times_seen\": 65.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.6444556113282087, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.05593234915850988, \"functional effect\": 0.0239, \"times_seen\": 50.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02951771761580071, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08565994901276379, \"functional effect\": -0.0798, \"times_seen\": 47.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.1856315609464974, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.09943612644906405, \"functional effect\": 0.017, \"times_seen\": 51.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.08423795225118502, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.09268760926952863, \"functional effect\": -0.0637, \"times_seen\": 27.0}, {\"site\": 18, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005188048421962044, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08711677138739435, \"functional effect\": -0.1084, \"times_seen\": 14.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.010595833040649483, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08679083494525108, \"functional effect\": -3.0652, \"times_seen\": 3.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0026931070457391466, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08726755812967663, \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.4170917058184027, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.11674025681056797, \"functional effect\": -0.24, \"times_seen\": 89.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04431849718240096, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08478564589231896, \"functional effect\": -0.6944, \"times_seen\": 24.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.09029244105996351, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0821264020458266, \"functional effect\": 0.0872, \"times_seen\": 13.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": 2.021064235527098, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.3548660790847957, \"functional effect\": 0.3967, \"times_seen\": 7.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0044010820871646286, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08769773719054176, \"functional effect\": -0.2889, \"times_seen\": 31.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.044138105518775415, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0901468225792627, \"functional effect\": -0.3205, \"times_seen\": 24.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.010705185553849026, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08678425667612608, \"functional effect\": -0.9589, \"times_seen\": 20.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004538781570586673, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08715598602367165, \"functional effect\": -0.2361, \"times_seen\": 81.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.8227662242094702, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.1546467661694058, \"functional effect\": 0.2149, \"times_seen\": 54.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.2326936084803831, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.10273331115685912, \"functional effect\": -0.2714, \"times_seen\": 60.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.002635389061229872, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08759047088715625, \"functional effect\": 0.03, \"times_seen\": 25.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.027235394079985237, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.089096819350908, \"functional effect\": -0.1833, \"times_seen\": 49.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01755252386538621, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08637333601755487, \"functional effect\": -0.0513, \"times_seen\": 105.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0930792202790948, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08196791585160576, \"functional effect\": -0.5133, \"times_seen\": 17.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.008493153060827327, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0879468368133719, \"functional effect\": -0.0266, \"times_seen\": 91.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.40685753856116924, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.11591505697888013, \"functional effect\": -0.3007, \"times_seen\": 133.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011262373328863842, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08675074592782316, \"functional effect\": -0.1003, \"times_seen\": 17.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.035415254458674404, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08531049778560013, \"functional effect\": 0.0735, \"times_seen\": 21.0}, {\"site\": 19, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.4150453530964277, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.06557260377883356, \"functional effect\": -0.0945, \"times_seen\": 25.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0041650427409017044, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.0871785672309594, \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.16767890273819738, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.09820642671415472, \"functional effect\": 0.2419, \"times_seen\": 60.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.17781967065114704, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.0772919875550803, \"functional effect\": 0.2046, \"times_seen\": 77.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.19935938384242108, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.07614657527121603, \"functional effect\": 0.383, \"times_seen\": 82.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03333549171920706, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.08543356852318926, \"functional effect\": -0.0425, \"times_seen\": 28.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06244308117052773, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.08372714634818135, \"functional effect\": 0.0782, \"times_seen\": 12.0}, {\"site\": 20, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0004803313667598665, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08740150999722202, \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.040465486350602924, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08501238586444267, \"functional effect\": 0.3483, \"times_seen\": 35.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.1258901334446725, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.09540260562940216, \"functional effect\": 0.3186, \"times_seen\": 138.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.037592808079795655, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08973876591144878, \"functional effect\": 0.0568, \"times_seen\": 78.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.4145788242458302, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.11653709599128989, \"functional effect\": 0.3517, \"times_seen\": 97.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.002992747435223463, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08724943498579704, \"functional effect\": 0.157, \"times_seen\": 5.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0025798441212816063, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08727440958931777, \"functional effect\": 0.3257, \"times_seen\": 1.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04705939274179137, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.09032954419028118, \"functional effect\": -0.0945, \"times_seen\": 130.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.4984677217761095, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.12351430701703964, \"functional effect\": 0.1923, \"times_seen\": 105.0}, {\"site\": 21, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.00453348230014754, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08715630616339314, \"functional effect\": 0.2954, \"times_seen\": 3.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.2147500132976594, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.10146347342129672, \"functional effect\": -0.2283, \"times_seen\": 109.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.20104491720718157, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.07605766344780003, \"functional effect\": 0.1231, \"times_seen\": 79.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.019610246109156824, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08862715375983862, \"functional effect\": 0.1078, \"times_seen\": 7.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.10287819566008247, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08141306537640496, \"functional effect\": -0.1722, \"times_seen\": 83.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.10316006886680494, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.0813971604765468, \"functional effect\": -0.1872, \"times_seen\": 24.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.028425653150868695, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08572481483547335, \"functional effect\": 0.1051, \"times_seen\": 23.0}, {\"site\": 22, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.021166834553189504, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08872282917958708, \"functional effect\": -2.3803, \"times_seen\": 2.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.030672329559295664, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08930932792337781, \"functional effect\": 0.0926, \"times_seen\": 15.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.11537232979634587, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08071105014495554, \"functional effect\": 0.0352, \"times_seen\": 141.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.3001540544370887, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.07100814317954297, \"functional effect\": 0.1144, \"times_seen\": 36.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.17444795838261007, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.07747283735582972, \"functional effect\": 0.0207, \"times_seen\": 62.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.010889175504241528, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08809301994245207, \"functional effect\": 0.0088, \"times_seen\": 28.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.11207976491602964, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08089546184658888, \"functional effect\": -0.2311, \"times_seen\": 30.0}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 23, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.05268231761723446, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08429553514946916, \"functional effect\": -0.0953, \"times_seen\": 60.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -1.2326637894574985, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.037204438529105606, \"functional effect\": 0.0184, \"times_seen\": 59.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.18073955451089094, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.07713571378067574, \"functional effect\": -0.2565, \"times_seen\": 36.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.007704562069979877, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08696494480894695, \"functional effect\": 0.2929, \"times_seen\": 1.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.015189756069062728, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08835601132008501, \"functional effect\": -0.4616, \"times_seen\": 23.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0011730687120194315, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.0875017338828534, \"functional effect\": -0.0642, \"times_seen\": 2.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009473203042684904, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08685839732742852, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.00670910752628098, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08783814843186552, \"functional effect\": -0.0902, \"times_seen\": 1.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06252530902914967, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08372237437104063, \"functional effect\": -0.1515, \"times_seen\": 23.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0007181203518858698, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08747414489620077, \"functional effect\": 0.1116, \"times_seen\": 3.0}, {\"site\": 24, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07922894495600877, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08275862015473476, \"functional effect\": -0.1582, \"times_seen\": 14.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.2178693821508947, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.07517584368309306, \"functional effect\": -0.0124, \"times_seen\": 91.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.015506236370157047, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.08837539587716503, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.2276193216794139, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.07466950744771034, \"functional effect\": -0.0359, \"times_seen\": 106.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.6080854014260721, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.057360322471451584, \"functional effect\": 0.0811, \"times_seen\": 119.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0031358977623627605, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.08762086358764967, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01012825863784214, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.08804656952238447, \"functional effect\": -0.1673, \"times_seen\": 73.0}, {\"site\": 25, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.9169970171105959, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.0463041505928815, \"functional effect\": -0.2096, \"times_seen\": 102.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.06562836854554359, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08354249136784864, \"functional effect\": -2.9872, \"times_seen\": 8.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.3101794343852149, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07051641356807897, \"functional effect\": 0.0665, \"times_seen\": 177.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.28623887706499684, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07169634923585952, \"functional effect\": -0.25, \"times_seen\": 43.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.1654697588479135, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.03897823534706009, \"functional effect\": -0.0853, \"times_seen\": 38.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.041388790312321046, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08495799657298643, \"functional effect\": -0.1077, \"times_seen\": 73.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.4654516070190383, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.06332112682715131, \"functional effect\": -0.1031, \"times_seen\": 73.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.01632689251670981, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08644674505075164, \"functional effect\": -0.2147, \"times_seen\": 110.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0007268637893927726, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08738657581885532, \"functional effect\": -0.082, \"times_seen\": 157.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.023665256622745632, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08600814437424462, \"functional effect\": 0.0365, \"times_seen\": 47.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.15362159872677708, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07859932579057834, \"functional effect\": -0.11, \"times_seen\": 62.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06060759037671796, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.0838337372801177, \"functional effect\": -0.0377, \"times_seen\": 300.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.9695642035351155, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.04464734332930448, \"functional effect\": 0.0335, \"times_seen\": 74.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.13017134522043486, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07988735650582574, \"functional effect\": -0.2281, \"times_seen\": 43.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.3286235519496271, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.10979664666313069, \"functional effect\": -0.125, \"times_seen\": 96.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.19554307818063538, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07634826952528258, \"functional effect\": -0.0945, \"times_seen\": 207.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04902632507858294, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08450942281076544, \"functional effect\": -0.0988, \"times_seen\": 185.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.09287154396705255, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.09324394734192731, \"functional effect\": 0.0287, \"times_seen\": 161.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.018919415447661556, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.0885847250435647, \"functional effect\": -0.0265, \"times_seen\": 122.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.03029398449600497, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08928590972889089, \"functional effect\": -0.2387, \"times_seen\": 26.0}, {\"site\": 26, \"wildtype\": \"P\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.16574282762180256, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07794171673518942, \"functional effect\": 0.033, \"times_seen\": 53.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.25972696191495076, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.10467648630788465, \"functional effect\": -0.1383, \"times_seen\": 5.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.08728495240267689, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08229778396692622, \"functional effect\": -0.081, \"times_seen\": 11.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.02341929532496418, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08886145915701497, \"functional effect\": 0.0321, \"times_seen\": 27.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.00730016718496606, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.0878741423329361, \"functional effect\": -0.2663, \"times_seen\": 13.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.05214272512962522, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.0843270690103359, \"functional effect\": -0.7404, \"times_seen\": 29.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.10917423732179221, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.09430359524197428, \"functional effect\": -0.2984, \"times_seen\": 57.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.015616291236803779, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08648933499313508, \"functional effect\": -0.1758, \"times_seen\": 107.0}, {\"site\": 27, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.024631017422093966, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08595058855251587, \"functional effect\": -0.2406, \"times_seen\": 70.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.17595813915947334, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.07739178295949767, \"functional effect\": -0.1402, \"times_seen\": 34.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.02099146148344773, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08871204474573265, \"functional effect\": -0.1212, \"times_seen\": 26.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.01838354274807613, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.0885518273629213, \"functional effect\": -0.0107, \"times_seen\": 25.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.3628151192349123, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.11242988429851174, \"functional effect\": -0.2076, \"times_seen\": 147.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0038944354409477006, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08719492090839408, \"functional effect\": -0.3199, \"times_seen\": 1.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.08099781970913056, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.09247967679588952, \"functional effect\": -0.034, \"times_seen\": 30.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.002522998497506743, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08727784847685414, \"functional effect\": 0.2182, \"times_seen\": 1.0}, {\"site\": 28, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.027035354382803956, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08908446631393191, \"functional effect\": -2.7073, \"times_seen\": 1.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.030619431702884448, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08930605336759037, \"functional effect\": -0.0217, \"times_seen\": 135.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0021271153544263083, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08730180126592792, \"functional effect\": 0.0151, \"times_seen\": 37.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.09981167267500483, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09369358082897591, \"functional effect\": -0.9919, \"times_seen\": 35.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.059040822831305316, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09108284523689722, \"functional effect\": -0.6248, \"times_seen\": 22.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.23181999207652215, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.1026711203714749, \"functional effect\": -0.3225, \"times_seen\": 60.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.009908707545033875, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08803317150742143, \"functional effect\": -0.2236, \"times_seen\": 19.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.2027975416757746, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.07596532266720031, \"functional effect\": -0.2165, \"times_seen\": 76.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.19041690459568214, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.0766200321709814, \"functional effect\": -0.1728, \"times_seen\": 144.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.04022268685581148, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08990249927380012, \"functional effect\": -0.0741, \"times_seen\": 29.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.19455096815178982, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.07640079062787443, \"functional effect\": -0.2727, \"times_seen\": 120.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.08672193458834566, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09284733304784926, \"functional effect\": -0.0634, \"times_seen\": 31.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0434590434975487, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09010440136246722, \"functional effect\": -1.1027, \"times_seen\": 54.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.18554192472043218, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.07687937520210526, \"functional effect\": -0.7726, \"times_seen\": 117.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05750182892359134, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08401440473698123, \"functional effect\": -0.2614, \"times_seen\": 22.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.12438186631551877, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09530291898746553, \"functional effect\": -0.0754, \"times_seen\": 56.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.007709881973102085, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08696462412840443, \"functional effect\": -0.1188, \"times_seen\": 187.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.06435786627071423, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09141914982992629, \"functional effect\": -0.1554, \"times_seen\": 63.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.08644479174559735, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08234572444997552, \"functional effect\": -0.3719, \"times_seen\": 28.0}, {\"site\": 29, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -2.07751815889952, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.020714203933046578, \"functional effect\": -0.2473, \"times_seen\": 56.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.1334530253081973, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.07970584427057809, \"functional effect\": -0.2915, \"times_seen\": 19.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.005672142520743705, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08708754439275235, \"functional effect\": -1.4364, \"times_seen\": 1.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.02071087912176867, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08869479327261409, \"functional effect\": -0.1785, \"times_seen\": 95.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.023441496640828688, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08602148515161742, \"functional effect\": 0.0096, \"times_seen\": 25.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012120135189172194, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08669918314939937, \"functional effect\": 0.1346, \"times_seen\": 72.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.010759545049482636, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08808510487732178, \"functional effect\": -0.1372, \"times_seen\": 13.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.16514814009337858, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.09803430489647247, \"functional effect\": 0.1031, \"times_seen\": 93.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.039770530842676045, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08505334674389076, \"functional effect\": 0.0444, \"times_seen\": 42.0}, {\"site\": 30, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12814758305414403, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.07999949833257333, \"functional effect\": -0.1011, \"times_seen\": 33.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.07033925238854992, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08327014197358847, \"functional effect\": -1.6643, \"times_seen\": 14.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.18614536615969815, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.09947154620000792, \"functional effect\": -0.6806, \"times_seen\": 12.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.027561338087899807, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08911695101722901, \"functional effect\": -2.6768, \"times_seen\": 1.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.013248545471154817, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08663139751422065, \"functional effect\": -0.5595, \"times_seen\": 3.0}, {\"site\": 31, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.020732471389189034, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08869612074375136, \"functional effect\": -2.2492, \"times_seen\": 3.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.027525931101839013, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.08577829291578364, \"functional effect\": 0.3272, \"times_seen\": 4.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.11545585078843051, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.09471509609541057, \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.2783512877442271, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.03604470266527557, \"functional effect\": 0.2503, \"times_seen\": 32.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011773875892637495, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.08671999420106478, \"functional effect\": 0.2702, \"times_seen\": 7.0}, {\"site\": 32, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.6182518685876227, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.05695753328725092, \"functional effect\": -0.0009, \"times_seen\": 27.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.15240427375684584, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.0786656747400298, \"functional effect\": -0.5022, \"times_seen\": 11.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0647182314670563, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.09144198791683904, \"functional effect\": -0.3319, \"times_seen\": 74.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.13250862306909597, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.0958412788796685, \"functional effect\": -0.0638, \"times_seen\": 14.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.021870056782355995, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.08611523416559147, \"functional effect\": -0.0747, \"times_seen\": 4.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3926615062146313, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.06659791586602998, \"functional effect\": -0.1335, \"times_seen\": 6.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.019305813882727552, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.08626843129362859, \"functional effect\": -0.1264, \"times_seen\": 16.0}, {\"site\": 33, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.007826642873773127, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.0869575861497145, \"functional effect\": -1.913, \"times_seen\": 3.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.05860142928064372, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08395039462424982, \"functional effect\": -2.8329, \"times_seen\": 2.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.01599624604205355, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08840541757444309, \"functional effect\": 0.0507, \"times_seen\": 7.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.016235015091657767, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08645225055054694, \"functional effect\": -0.6047, \"times_seen\": 13.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.006834737888532675, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08701739319057417, \"functional effect\": -1.2083, \"times_seen\": 15.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0116478854537487, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08672756778169866, \"functional effect\": -2.7512, \"times_seen\": 3.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.005400200739462964, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08710396156579707, \"functional effect\": -2.963, \"times_seen\": 1.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0026364241801745468, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08727098690173246, \"functional effect\": -1.472, \"times_seen\": 1.0}, {\"site\": 34, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.033905970502350787, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08539979256779899, \"functional effect\": -1.6049, \"times_seen\": 3.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.4009457296353712, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.0662165940968242, \"functional effect\": -0.7398, \"times_seen\": 31.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.012494972641794038, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.08819112679836559, \"functional effect\": -2.2796, \"times_seen\": 7.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05857849904726532, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.08395172894466021, \"functional effect\": -0.2414, \"times_seen\": 15.0}, {\"site\": 35, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04274114143546858, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.09005957550385878, \"functional effect\": -0.5298, \"times_seen\": 21.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.00794999476640911, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.0879137320605276, \"functional effect\": -0.2626, \"times_seen\": 14.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0020791913549996622, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.08730470133894848, \"functional effect\": -0.2184, \"times_seen\": 7.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.14151717825251078, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.07926155975958105, \"functional effect\": -0.3847, \"times_seen\": 33.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.2371143759332259, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.103048593739091, \"functional effect\": 0.2168, \"times_seen\": 79.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.018987130891115086, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.08628748959607901, \"functional effect\": 0.1621, \"times_seen\": 4.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005962230634218677, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.08707003513331428, \"functional effect\": -0.0959, \"times_seen\": 9.0}, {\"site\": 36, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.019303342893960292, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08860830219054254, \"functional effect\": -2.812, \"times_seen\": 2.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0007878288028366488, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08738288313879773, \"functional effect\": -1.4704, \"times_seen\": 1.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0024954794055391124, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08758197695179576, \"functional effect\": -0.9055, \"times_seen\": 5.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.040913536379076375, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.0849859881249567, \"functional effect\": -0.2204, \"times_seen\": 18.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.024628048754918766, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08893594239855394, \"functional effect\": -2.3453, \"times_seen\": 2.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.013589654973284966, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08661091688676197, \"functional effect\": -2.9696, \"times_seen\": 2.0}, {\"site\": 37, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.07085889164275085, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08324015459478082, \"functional effect\": -2.6265, \"times_seen\": 3.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.017322542360944593, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08638710597764616, \"functional effect\": -0.0741, \"times_seen\": 4.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0035940646459743215, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08764869438494828, \"functional effect\": -1.4529, \"times_seen\": 5.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014301729635176895, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08656817866422958, \"functional effect\": -0.5605, \"times_seen\": 3.0}, {\"site\": 38, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004410751036858831, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08716372093800712, \"functional effect\": -0.37, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.009123306260989526, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08687946564647457, \"functional effect\": -0.2309, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.01487223777695345, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08833656745841446, \"functional effect\": -0.2172, \"times_seen\": 4.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03821762825703398, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.0897776395012633, \"functional effect\": -1.6753, \"times_seen\": 4.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.006873611987557036, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08701504849742021, \"functional effect\": 0.35, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.003952378927370744, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08719141893735118, \"functional effect\": -1.1557, \"times_seen\": 1.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.021753813799120354, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08612217305061613, \"functional effect\": 0.3631, \"times_seen\": 36.0}, {\"site\": 39, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0018971956801148498, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.0873157155032968, \"functional effect\": -0.0649, \"times_seen\": 20.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.05084083375643289, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.09056661708254726, \"functional effect\": -0.0319, \"times_seen\": 5.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.040269003024190834, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.08990538554291187, \"functional effect\": -0.0019, \"times_seen\": 2.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 3.754567027243518, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 1.1800511321579266, \"functional effect\": -0.6738, \"times_seen\": 6.0}, {\"site\": 40, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.08904581128492063, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.09299701098902056, \"functional effect\": -2.2738, \"times_seen\": 1.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.015835840802203467, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08839558881403202, \"functional effect\": -0.6505, \"times_seen\": 12.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.018944980450202268, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08858629480621173, \"functional effect\": -0.4399, \"times_seen\": 8.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.015216761326283766, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08651329006364822, \"functional effect\": -0.3101, \"times_seen\": 1.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04314092908417809, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08485487856208317, \"functional effect\": 0.1298, \"times_seen\": 29.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0035654076307669313, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08721480925961046, \"functional effect\": -0.2988, \"times_seen\": 2.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05837350898832121, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.09104072490866413, \"functional effect\": -0.2941, \"times_seen\": 11.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004694233075617976, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08714659540478834, \"functional effect\": -0.0335, \"times_seen\": 25.0}, {\"site\": 41, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.001132780855502941, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.0873619921668896, \"functional effect\": -0.6873, \"times_seen\": 1.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.047040794638358974, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.09032837973949294, \"functional effect\": -2.0016, \"times_seen\": 2.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02325857838049123, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08603239244492618, \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.12157453038564182, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08036481505745394, \"functional effect\": 0.3356, \"times_seen\": 25.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01563049534963958, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.0864884834630536, \"functional effect\": 0.3644, \"times_seen\": 4.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.008239988183795751, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08693267557554119, \"functional effect\": 0.0304, \"times_seen\": 5.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05694372452575321, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08404691186983905, \"functional effect\": -1.3902, \"times_seen\": 6.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.010328885823236333, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08680689566137231, \"functional effect\": -0.8912, \"times_seen\": 1.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008634132728781649, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08690892879687805, \"functional effect\": -0.3052, \"times_seen\": 4.0}, {\"site\": 42, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 43, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 43, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 1.2077945216403396, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": 0.20195095422857884, \"functional effect\": 0.171, \"times_seen\": 8.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.054369932687296105, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08419698678036892, \"functional effect\": -3.1109, \"times_seen\": 2.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.002094816683550325, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08730375577719328, \"functional effect\": -2.5511, \"times_seen\": 1.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.013778635029016176, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08826963126971561, \"functional effect\": -1.3754, \"times_seen\": 14.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0036875693477844648, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08720742456674273, \"functional effect\": -1.3611, \"times_seen\": 3.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0034597368254806592, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.0876405338869548, \"functional effect\": -1.7575, \"times_seen\": 4.0}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 44, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02043868328662493, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08867806064700963, \"functional effect\": -2.5003, \"times_seen\": 2.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.005225004308416493, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.08774783561676157, \"functional effect\": 0.032, \"times_seen\": 15.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.09930696261344679, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.0816148441113738, \"functional effect\": -0.6868, \"times_seen\": 35.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03140950584871846, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.08935497412047232, \"functional effect\": -0.596, \"times_seen\": 5.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.3650870811112067, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.06788305320271483, \"functional effect\": -1.1187, \"times_seen\": 26.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.2716387085752269, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.10554433532430388, \"functional effect\": -0.5499, \"times_seen\": 36.0}, {\"site\": 45, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03326072487935882, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.08543799618341824, \"functional effect\": -0.2105, \"times_seen\": 20.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -2.512771393788145, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.01531947803186615, \"functional effect\": 0.0387, \"times_seen\": 4.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.017435653573197353, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08638033325925246, \"functional effect\": -2.7094, \"times_seen\": 1.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.01282938395487771, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08821157154103369, \"functional effect\": -0.1556, \"times_seen\": 4.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.10219918092836074, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.0814513920361221, \"functional effect\": -2.2301, \"times_seen\": 12.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014047810225436967, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.0865834163095502, \"functional effect\": -0.9944, \"times_seen\": 4.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006564873204176519, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08703367183375808, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.115112315529544, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.09469254517476303, \"functional effect\": -2.5774, \"times_seen\": 17.0}, {\"site\": 46, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.011670146134466125, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08814072003419518, \"functional effect\": 0.0297, \"times_seen\": 5.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.036357517111722845, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08966196101581299, \"functional effect\": 0.1629, \"times_seen\": 6.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.00134857366165489, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.0873489258714737, \"functional effect\": -0.5387, \"times_seen\": 11.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.2955251620225141, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.10730636124423022, \"functional effect\": -0.4671, \"times_seen\": 2.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08147080158813756, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08263011837326692, \"functional effect\": -0.1979, \"times_seen\": 30.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.017430329430947644, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08638065203904821, \"functional effect\": 0.3864, \"times_seen\": 5.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.030400779431715392, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08560753330295247, \"functional effect\": 0.1746, \"times_seen\": 7.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.004827596961139219, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.0871385398760195, \"functional effect\": -0.2582, \"times_seen\": 2.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.8800066418873268, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.04750672960986759, \"functional effect\": -0.0317, \"times_seen\": 3.0}, {\"site\": 47, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.00877488781868522, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08690045002831302, \"functional effect\": -0.8417, \"times_seen\": 2.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.00044693410406082757, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.0874577037530014, \"functional effect\": -0.2817, \"times_seen\": 3.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.08336849134930202, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08252149996082311, \"functional effect\": -1.8053, \"times_seen\": 10.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.010662148285603659, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08678684558988664, \"functional effect\": -0.17, \"times_seen\": 2.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.015437536143346368, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08837118759681947, \"functional effect\": -0.3694, \"times_seen\": 2.0}, {\"site\": 48, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.005481513882024104, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08709905235279636, \"functional effect\": -0.6601, \"times_seen\": 2.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0017436341514302821, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08753634642225731, \"functional effect\": -0.2204, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.09649550239275916, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.093478464645725, \"functional effect\": 0.2969, \"times_seen\": 21.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.017589568687140886, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08637111819350556, \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.014322773458434123, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08830293003082669, \"functional effect\": -0.0998, \"times_seen\": 20.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005123767693472259, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08712065304923336, \"functional effect\": -2.7292, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.026336243740826316, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08904130763582861, \"functional effect\": -2.5739, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.15823950764452124, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.09756597036006752, \"functional effect\": 0.0067, \"times_seen\": 39.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.061708386091806594, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08376979540867659, \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.07847742191184827, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.0923182552309844, \"functional effect\": -1.4669, \"times_seen\": 3.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010566516204303064, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08679259862952605, \"functional effect\": -0.026, \"times_seen\": 3.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.018157189527046216, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08853793501668465, \"functional effect\": 0.2159, \"times_seen\": 1.0}, {\"site\": 49, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.014761436723070488, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08654059856970432, \"functional effect\": -0.1723, \"times_seen\": 20.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.011302854040665734, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.0867483118148766, \"functional effect\": 0.0423, \"times_seen\": 2.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.003979013919849174, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08718980922685493, \"functional effect\": -0.5661, \"times_seen\": 2.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02791980368941572, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08575487763694564, \"functional effect\": -0.3996, \"times_seen\": 10.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0699383332635488, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.09177345166168502, \"functional effect\": -0.0512, \"times_seen\": 20.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.003022799388605184, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08724761756176092, \"functional effect\": 0.0653, \"times_seen\": 2.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014951401622052081, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08652920420477565, \"functional effect\": -0.4275, \"times_seen\": 5.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.7555456793977604, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.14760648642354354, \"functional effect\": -0.1203, \"times_seen\": 45.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.05930703635883359, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.09109965386388606, \"functional effect\": -0.1371, \"times_seen\": 33.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006948859375271231, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08701051012711052, \"functional effect\": -1.2814, \"times_seen\": 7.0}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 50, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0067400949851025085, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08702310184600442, \"functional effect\": 0.0492, \"times_seen\": 9.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.06951966108801075, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.09174682273810053, \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.010002766600048365, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08682652045834549, \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02892304749386811, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08569526480077216, \"functional effect\": -0.0949, \"times_seen\": 24.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.027954761713494147, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08914125656618327, \"functional effect\": 0.3228, \"times_seen\": 6.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03754553984143321, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08518462115075515, \"functional effect\": 0.0009, \"times_seen\": 3.0}, {\"site\": 51, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.09679789522461374, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.09349806004148813, \"functional effect\": -1.0619, \"times_seen\": 22.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -1.086611101304692, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.04116811621442545, \"functional effect\": 0.3659, \"times_seen\": 64.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.014124984960998455, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08657878478774657, \"functional effect\": 0.042, \"times_seen\": 6.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07219173107484989, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.0831632883658294, \"functional effect\": -0.0164, \"times_seen\": 29.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.025402404484253, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08898369091095673, \"functional effect\": 0.0047, \"times_seen\": 16.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0896587395799552, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08216248385990468, \"functional effect\": 0.1996, \"times_seen\": 23.0}, {\"site\": 52, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03197496082906568, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.0893900030882778, \"functional effect\": 0.3851, \"times_seen\": 3.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.013347628522934843, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.086625447948825, \"functional effect\": -0.3682, \"times_seen\": 13.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.11849107782471598, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.094914573070836, \"functional effect\": 0.1243, \"times_seen\": 4.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.08172870921280316, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.09252654016457315, \"functional effect\": 0.0635, \"times_seen\": 34.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.22992763493679014, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.07455013170021625, \"functional effect\": 0.0979, \"times_seen\": 173.0}, {\"site\": 53, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008323868400992862, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.08793651780866901, \"functional effect\": -2.8725, \"times_seen\": 5.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.023619692801442403, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08601086076370602, \"functional effect\": -0.2798, \"times_seen\": 11.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.019825619439654912, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.0862373542252242, \"functional effect\": 0.0382, \"times_seen\": 7.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.5622730857202511, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.12909951018521068, \"functional effect\": -2.1354, \"times_seen\": 14.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.002267800147103044, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08729328842250655, \"functional effect\": -1.0069, \"times_seen\": 2.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.04235206560241313, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08490128976988158, \"functional effect\": -0.7697, \"times_seen\": 12.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.041734894108507684, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08493761752022595, \"functional effect\": 0.1398, \"times_seen\": 6.0}, {\"site\": 54, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.035642216737343836, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08961751687779554, \"functional effect\": -0.5728, \"times_seen\": 2.0}, {\"site\": 55, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 55, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.008914965245004928, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": 0.08689201290188923, \"functional effect\": -0.7282, \"times_seen\": 2.0}, {\"site\": 55, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07460359500916207, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": 0.08302437406840688, \"functional effect\": 0.2628, \"times_seen\": 20.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.013577568827043742, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08825733012338544, \"functional effect\": -1.7867, \"times_seen\": 6.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0002416409484107959, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08744525954955207, \"functional effect\": -0.2693, \"times_seen\": 5.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.06066352505173594, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08383048702845956, \"functional effect\": 0.1187, \"times_seen\": 5.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.001978222284948699, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08755058134867442, \"functional effect\": -2.2717, \"times_seen\": 4.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005593135606448247, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08709231373510455, \"functional effect\": -0.3305, \"times_seen\": 1.0}, {\"site\": 56, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0010562566571133698, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08749464933395909, \"functional effect\": -0.0474, \"times_seen\": 13.0}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.003201492801737814, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.08723681166818187, \"functional effect\": -2.8649, \"times_seen\": 1.0}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.012924430083175167, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.08821738319512062, \"functional effect\": -1.402, \"times_seen\": 12.0}, {\"site\": 57, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.019612177016236798, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.0886272723787486, \"functional effect\": -1.9551, \"times_seen\": 2.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.05933843184461218, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.09110163636810698, \"functional effect\": -2.9909, \"times_seen\": 3.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0038460105944445825, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.08719784770262679, \"functional effect\": -0.6816, \"times_seen\": 10.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.013207408627490563, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.08663386774733542, \"functional effect\": -1.1986, \"times_seen\": 4.0}, {\"site\": 58, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.05472486845537078, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.09081076973384539, \"functional effect\": -1.701, \"times_seen\": 1.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.006561201544429756, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.0870338933347871, \"functional effect\": -0.1, \"times_seen\": 1.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.01882047847946753, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.08857865029917043, \"functional effect\": -2.142, \"times_seen\": 1.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.14491493054308485, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.07907510714529367, \"functional effect\": -0.1372, \"times_seen\": 28.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04701411476941267, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.08462737523448204, \"functional effect\": 0.2057, \"times_seen\": 24.0}, {\"site\": 59, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03081721913276874, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.08558282591175091, \"functional effect\": -0.0095, \"times_seen\": 35.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.006211557464499155, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08780786043640526, \"functional effect\": -0.2894, \"times_seen\": 15.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.006291637647638882, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08781273455359832, \"functional effect\": -0.4102, \"times_seen\": 18.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.010076898098706403, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08804343508394956, \"functional effect\": -1.6135, \"times_seen\": 34.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.009011272192353394, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08688621262881144, \"functional effect\": -0.4363, \"times_seen\": 12.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.007508141002078685, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.0869767857799955, \"functional effect\": -0.5157, \"times_seen\": 2.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.007312335155776241, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.0869885912679408, \"functional effect\": -2.112, \"times_seen\": 2.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.029364952982581554, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08922843207813819, \"functional effect\": -0.3375, \"times_seen\": 15.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.005163290915389172, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08711826637592979, \"functional effect\": -2.9879, \"times_seen\": 1.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03505000224839494, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08533209888059967, \"functional effect\": -1.0799, \"times_seen\": 3.0}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 60, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04210511858442517, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08491582362092572, \"functional effect\": -0.0547, \"times_seen\": 21.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.01625864349639209, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08842149821904219, \"functional effect\": -0.1119, \"times_seen\": 8.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01908312477197408, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08628174839977748, \"functional effect\": -0.192, \"times_seen\": 7.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.001209629761701119, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08735733872694312, \"functional effect\": -0.1077, \"times_seen\": 29.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.13239406341222862, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.079764371148852, \"functional effect\": -0.2256, \"times_seen\": 16.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.010917958315944819, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08809477747958006, \"functional effect\": -0.0966, \"times_seen\": 16.0}, {\"site\": 61, \"wildtype\": \"N\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.00731870467759439, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08787527145356454, \"functional effect\": -1.2228, \"times_seen\": 5.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.09384005070034118, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.09330656467098053, \"functional effect\": -1.2254, \"times_seen\": 6.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.005071824393484421, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08773851937731296, \"functional effect\": -0.5063, \"times_seen\": 18.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0040271656034638805, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08718689921058133, \"functional effect\": -2.1029, \"times_seen\": 2.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.001430795414225379, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08734394784291348, \"functional effect\": -2.957, \"times_seen\": 1.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.019962923400021308, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08622914724696697, \"functional effect\": -1.0437, \"times_seen\": 30.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.00012935529947765526, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08742277545462349, \"functional effect\": -0.8009, \"times_seen\": 11.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.9425570834948315, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.1680356710665828, \"functional effect\": 0.0795, \"times_seen\": 54.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.06160912352312868, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.09124513627697156, \"functional effect\": -0.0591, \"times_seen\": 84.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.26240005749099576, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.104870615786207, \"functional effect\": 0.0445, \"times_seen\": 21.0}, {\"site\": 62, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.006391397719005788, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08704413774359405, \"functional effect\": -0.1452, \"times_seen\": 15.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.00877882893776618, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08690021263611006, \"functional effect\": -0.1278, \"times_seen\": 16.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0944116918994852, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08189224532084015, \"functional effect\": -0.3034, \"times_seen\": 50.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02401228191546094, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08598745849730846, \"functional effect\": -0.7167, \"times_seen\": 5.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.11849135667837497, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.0949145914165555, \"functional effect\": -0.1516, \"times_seen\": 24.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.040285799602038985, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08990643227250833, \"functional effect\": -0.2228, \"times_seen\": 5.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.11163250728950275, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.0944644201625935, \"functional effect\": -0.1262, \"times_seen\": 17.0}, {\"site\": 63, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.013836291803486302, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08659611152903138, \"functional effect\": -2.6819, \"times_seen\": 2.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"-\", \"log2 fold change IC90\": -2.851623590166819, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.012112653477753615, \"functional effect\": 0.1828, \"times_seen\": 20.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.01484404272257222, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08833484108526209, \"functional effect\": 0.0504, \"times_seen\": 94.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.10457182004401092, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.09400323174363624, \"functional effect\": -0.0032, \"times_seen\": 19.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.033664164266794104, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08541410739694302, \"functional effect\": 0.0158, \"times_seen\": 15.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.05666048320079953, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.09093268921658068, \"functional effect\": -0.1005, \"times_seen\": 23.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.004524714478809088, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08770525280906381, \"functional effect\": -0.0708, \"times_seen\": 101.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.28957034105393076, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.07153097940299939, \"functional effect\": -0.1623, \"times_seen\": 122.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.007105433870859366, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08786228198293336, \"functional effect\": -0.0457, \"times_seen\": 20.0}, {\"site\": 64, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.049118534621385185, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08450402158181966, \"functional effect\": 0.2061, \"times_seen\": 17.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -1.171280737463801, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.03882155209899321, \"functional effect\": -0.2315, \"times_seen\": 24.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009779473006837035, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08683996010126657, \"functional effect\": -0.1169, \"times_seen\": 1.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.028204378073438337, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08915668119884576, \"functional effect\": 0.0363, \"times_seen\": 31.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03828614107058598, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08978190309443869, \"functional effect\": -0.5773, \"times_seen\": 14.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.00942680343654329, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08800377065606975, \"functional effect\": 0.0132, \"times_seen\": 9.0}, {\"site\": 65, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018252850159722722, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08633141805338719, \"functional effect\": -0.1808, \"times_seen\": 35.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.13723408930389958, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.09615571626278552, \"functional effect\": -0.1132, \"times_seen\": 30.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.034242526440109305, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08953061289870076, \"functional effect\": 0.0423, \"times_seen\": 15.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.05607464443195423, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.09089577144911956, \"functional effect\": 0.113, \"times_seen\": 26.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.08480440531987926, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08243940719522919, \"functional effect\": -0.0595, \"times_seen\": 24.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.2580193478085417, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.07311255596532887, \"functional effect\": 0.1133, \"times_seen\": 44.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0075840631690622185, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08697220872655378, \"functional effect\": -0.1817, \"times_seen\": 13.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0502059825178121, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08444034970825413, \"functional effect\": 0.0272, \"times_seen\": 15.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.39496249208869766, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.06649178205351222, \"functional effect\": -0.0116, \"times_seen\": 39.0}, {\"site\": 66, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.20406274982990405, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.07589873214643555, \"functional effect\": 0.1116, \"times_seen\": 117.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.013011779749744302, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08664561606210099, \"functional effect\": -2.6734, \"times_seen\": 5.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.118008689593772, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.0805636946321471, \"functional effect\": -0.1529, \"times_seen\": 19.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.12655696712623166, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08008774889568118, \"functional effect\": -0.1023, \"times_seen\": 220.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.03124803953116586, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08934497407828232, \"functional effect\": -0.3216, \"times_seen\": 99.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": -3.7669286333232597, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.006422513411096305, \"functional effect\": -0.033, \"times_seen\": 115.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.07934765252734394, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.09237395820671683, \"functional effect\": -0.0541, \"times_seen\": 110.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -1.4278351782430272, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.03249692831867448, \"functional effect\": -0.0415, \"times_seen\": 89.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.009310307115661713, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.0879966647180155, \"functional effect\": -0.0284, \"times_seen\": 116.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.016913556004452927, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08846164633716917, \"functional effect\": -0.0483, \"times_seen\": 63.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.8165572255767157, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.15398263531717, \"functional effect\": 0.0065, \"times_seen\": 106.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.15284390517402585, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.0786417066578913, \"functional effect\": -0.3331, \"times_seen\": 58.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.1455800408625649, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07903866039334725, \"functional effect\": 0.0207, \"times_seen\": 188.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.44039997407173526, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.11864163750641533, \"functional effect\": 0.0777, \"times_seen\": 82.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.03586036526460142, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.089631068880753, \"functional effect\": -0.0498, \"times_seen\": 68.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.14778867697517822, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.09686175971905496, \"functional effect\": -0.0876, \"times_seen\": 152.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010290129743510719, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08805644894578069, \"functional effect\": -0.0541, \"times_seen\": 57.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.050710562465273966, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.09055843954179787, \"functional effect\": -0.1584, \"times_seen\": 122.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.014540469968242188, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08655385435778959, \"functional effect\": -0.0764, \"times_seen\": 270.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.279642836683107, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.072024897358662, \"functional effect\": 0.0328, \"times_seen\": 193.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.13815065992880907, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07944673199443525, \"functional effect\": 0.0267, \"times_seen\": 63.0}, {\"site\": 67, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.14993266433290023, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07880055942532177, \"functional effect\": -0.0282, \"times_seen\": 63.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.08836674483048866, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.0822360968144223, \"functional effect\": -0.0795, \"times_seen\": 15.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.02899826758907587, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08569079688637962, \"functional effect\": 0.008, \"times_seen\": 11.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.023665676814061246, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08600811932399556, \"functional effect\": -0.1689, \"times_seen\": 16.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.017665448323421748, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08636657555871463, \"functional effect\": -0.2093, \"times_seen\": 7.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.01962928602640693, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08862832342131313, \"functional effect\": -0.2424, \"times_seen\": 25.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.06561123510398162, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.09149860646971485, \"functional effect\": -0.0642, \"times_seen\": 37.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04436323615839159, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08478301667127516, \"functional effect\": -0.1163, \"times_seen\": 16.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02493938639504471, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08593221900000171, \"functional effect\": 0.094, \"times_seen\": 22.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.3232784315713346, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.06987905530254891, \"functional effect\": -0.0391, \"times_seen\": 106.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.00019394886378069228, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08744236886394703, \"functional effect\": -0.0412, \"times_seen\": 23.0}, {\"site\": 68, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008872478790427046, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08689457185427685, \"functional effect\": 0.0902, \"times_seen\": 19.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.2477956446517423, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.10381436498472965, \"functional effect\": 0.0673, \"times_seen\": 21.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.6599846786149938, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.13814612736803236, \"functional effect\": 0.1456, \"times_seen\": 56.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.01233073870347457, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08818108784260281, \"functional effect\": 0.3574, \"times_seen\": 8.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.026765345033357042, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.0890677951621223, \"functional effect\": 0.0848, \"times_seen\": 63.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.013865813602254562, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08827496535128014, \"functional effect\": -0.0858, \"times_seen\": 12.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.03632084701406899, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.0896596820372432, \"functional effect\": 0.0396, \"times_seen\": 69.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.027354850370782304, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08578846546285081, \"functional effect\": 0.0112, \"times_seen\": 15.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00138371856173358, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.0873467980261612, \"functional effect\": 0.04, \"times_seen\": 12.0}, {\"site\": 69, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.19825521375250302, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.07620487654184784, \"functional effect\": 0.1375, \"times_seen\": 93.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.050801926225386165, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08440547657032886, \"functional effect\": -0.1119, \"times_seen\": 16.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.3378813954707195, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.11050348250406972, \"functional effect\": 0.0703, \"times_seen\": 41.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.009878070187718174, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08683402545642604, \"functional effect\": 0.105, \"times_seen\": 3.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.005917678766985053, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08778997569232326, \"functional effect\": 0.0347, \"times_seen\": 25.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.008595777249013387, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.0869112393877357, \"functional effect\": -0.0627, \"times_seen\": 22.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.015025075040667826, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08652478557205431, \"functional effect\": -0.3069, \"times_seen\": 24.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04644709018897305, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.09029121503991534, \"functional effect\": 0.021, \"times_seen\": 9.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.009418195324543847, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08800324556654447, \"functional effect\": -0.0736, \"times_seen\": 35.0}, {\"site\": 70, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.027388527726849504, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08578646289481305, \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.02026897179669229, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08866762961327086, \"functional effect\": 0.1346, \"times_seen\": 16.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.018447828135942732, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08631975128578058, \"functional effect\": -0.126, \"times_seen\": 6.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.007000593464735424, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08785589727766065, \"functional effect\": 0.0507, \"times_seen\": 48.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08508102946841979, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08242360167569024, \"functional effect\": 0.0925, \"times_seen\": 16.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04725215342461645, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.09034161406464587, \"functional effect\": -0.0987, \"times_seen\": 21.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.024635832606348086, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.0859503016816123, \"functional effect\": 0.0129, \"times_seen\": 13.0}, {\"site\": 71, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.08855357525523465, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.09296528656371367, \"functional effect\": -0.0354, \"times_seen\": 19.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.04124699296053149, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08496634720193072, \"functional effect\": 0.1093, \"times_seen\": 11.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.018090082683151952, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08853381677753265, \"functional effect\": 0.0324, \"times_seen\": 18.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05298563540010615, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.09070135927372727, \"functional effect\": -0.0269, \"times_seen\": 15.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.04268296858524156, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.0900559441636064, \"functional effect\": -0.0726, \"times_seen\": 24.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.01625639061350216, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08842136014195781, \"functional effect\": 0.0406, \"times_seen\": 10.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.046109421183663124, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.09027008446401587, \"functional effect\": -0.1336, \"times_seen\": 11.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.015504634786195213, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08649602903837607, \"functional effect\": 0.0316, \"times_seen\": 12.0}, {\"site\": 72, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018662760901098818, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.086306892323654, \"functional effect\": 0.2905, \"times_seen\": 5.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.013853928013744604, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08827423810431369, \"functional effect\": -2.6083, \"times_seen\": 4.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.007176923096620983, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.0869967564426698, \"functional effect\": 0.068, \"times_seen\": 24.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.5732926958703273, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.05876046612243156, \"functional effect\": 0.0017, \"times_seen\": 177.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004856601801007692, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08713678800613889, \"functional effect\": 0.005, \"times_seen\": 140.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.08994203595730796, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09305480013134801, \"functional effect\": 0.1365, \"times_seen\": 192.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.8556378351361561, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.15821082083437193, \"functional effect\": 0.1601, \"times_seen\": 41.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.08149621167298456, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09251163025011391, \"functional effect\": 0.0954, \"times_seen\": 53.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.017515676947281567, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08849857425689604, \"functional effect\": 0.0146, \"times_seen\": 36.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.20051500651023563, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.10046726078802111, \"functional effect\": 0.1174, \"times_seen\": 59.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0586998461334292, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08394466794495116, \"functional effect\": 0.0065, \"times_seen\": 29.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.2231981444821902, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.07489868511385851, \"functional effect\": 0.0908, \"times_seen\": 113.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.08187590271836394, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08260691953065875, \"functional effect\": 0.0553, \"times_seen\": 37.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.013680753345968053, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08826364269504344, \"functional effect\": 0.0523, \"times_seen\": 81.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.13045455339224435, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09570491978755859, \"functional effect\": 0.0268, \"times_seen\": 92.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0048984549305640095, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08772797642428448, \"functional effect\": 0.1306, \"times_seen\": 24.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.2694594719949461, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.10538502761091532, \"functional effect\": -0.1142, \"times_seen\": 145.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.14769257661612908, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09685530780814905, \"functional effect\": 0.0969, \"times_seen\": 255.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.17484935655654316, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.07745128524060621, \"functional effect\": 0.0799, \"times_seen\": 89.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.09938447400686408, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09366584118452768, \"functional effect\": 0.0418, \"times_seen\": 159.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.04147897850819652, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08495268570081492, \"functional effect\": 0.1616, \"times_seen\": 39.0}, {\"site\": 73, \"wildtype\": \"G\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.19911446607244554, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.07615950332044874, \"functional effect\": 0.0413, \"times_seen\": 39.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.3960311656349054, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.06644254663302214, \"functional effect\": -2.5774, \"times_seen\": 7.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.029923478601035076, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08563586036133364, \"functional effect\": 0.0534, \"times_seen\": 16.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.03983559120688072, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08504951122994758, \"functional effect\": -0.0788, \"times_seen\": 136.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.03844574810084684, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08513148450174077, \"functional effect\": -0.1474, \"times_seen\": 29.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0728807312370145, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.0831235808481526, \"functional effect\": -0.0387, \"times_seen\": 38.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.09201595544894878, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08202834839182063, \"functional effect\": 0.062, \"times_seen\": 34.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.09983970100274574, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.09369540110271762, \"functional effect\": -0.0331, \"times_seen\": 56.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.20008091163991898, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.10043703557709749, \"functional effect\": -0.0309, \"times_seen\": 53.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.5114055548498666, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.12462694290466447, \"functional effect\": -0.0401, \"times_seen\": 87.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.9384054546477869, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.16755281161794666, \"functional effect\": -0.0742, \"times_seen\": 206.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.08869720176414803, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.0929745421193518, \"functional effect\": -0.1361, \"times_seen\": 65.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.23250846950618478, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.10272012838506325, \"functional effect\": 0.0384, \"times_seen\": 145.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.020274560951604848, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.0886679731218181, \"functional effect\": 0.0083, \"times_seen\": 43.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.03929973060663347, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08984500303579739, \"functional effect\": -0.0385, \"times_seen\": 153.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.1217259885624487, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.0803563785763371, \"functional effect\": 0.0178, \"times_seen\": 148.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.6854406078839808, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.14060530706409247, \"functional effect\": -0.0973, \"times_seen\": 24.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.45606308503088594, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.11993672850207165, \"functional effect\": -0.0877, \"times_seen\": 134.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.008564373604055776, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08795117853211637, \"functional effect\": 0.0426, \"times_seen\": 190.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.13680386410438994, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.07952093235034587, \"functional effect\": 0.0431, \"times_seen\": 93.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.06872133097836906, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08336357829512012, \"functional effect\": 0.0581, \"times_seen\": 32.0}, {\"site\": 74, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.11307035365409211, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.09455861403321142, \"functional effect\": -0.0973, \"times_seen\": 83.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.03462726779040272, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08535710631671156, \"functional effect\": 0.0154, \"times_seen\": 16.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0830945299440314, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08253717191653175, \"functional effect\": 0.0372, \"times_seen\": 19.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.013089863413384086, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08822749963127137, \"functional effect\": 0.0428, \"times_seen\": 17.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.051332098767223173, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08437446430275995, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.018935410535087294, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.0885857071834045, \"functional effect\": 0.0788, \"times_seen\": 17.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.5962095646264153, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.1321723137453026, \"functional effect\": -0.0458, \"times_seen\": 55.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.7587151572771688, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.14793112174435988, \"functional effect\": 0.0151, \"times_seen\": 72.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.07511655981825678, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.09210344350755967, \"functional effect\": 0.0427, \"times_seen\": 119.0}, {\"site\": 75, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04502628961021867, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08474405988965206, \"functional effect\": 0.0471, \"times_seen\": 42.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.06184479980789059, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08376187494834006, \"functional effect\": 0.2354, \"times_seen\": 16.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.11586770404217264, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08068334137008422, \"functional effect\": 0.1019, \"times_seen\": 78.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.027950252557011994, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08914097795480988, \"functional effect\": 0.1084, \"times_seen\": 114.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.04291682024952853, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.09007054284090205, \"functional effect\": 0.0788, \"times_seen\": 32.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.25980929043939405, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.10468245992414764, \"functional effect\": 0.0973, \"times_seen\": 89.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.5031787018644925, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.12391829017695877, \"functional effect\": 0.0149, \"times_seen\": 147.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.024973729876301153, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08593017340038275, \"functional effect\": 0.093, \"times_seen\": 22.0}, {\"site\": 76, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0410339032025677, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.0849788978762065, \"functional effect\": -0.0796, \"times_seen\": 44.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.004143643155523415, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.0876820895332671, \"functional effect\": -0.0415, \"times_seen\": 15.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02765288664919775, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08577074485421912, \"functional effect\": 0.0478, \"times_seen\": 69.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.020294659972616095, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08866920841536134, \"functional effect\": -0.0869, \"times_seen\": 28.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.005863612939213724, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08778668577405593, \"functional effect\": -0.1149, \"times_seen\": 16.0}, {\"site\": 77, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.010072306238080867, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08804315485664714, \"functional effect\": 0.0759, \"times_seen\": 11.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.020218053682238526, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08866450025556596, \"functional effect\": -2.1444, \"times_seen\": 2.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.015540116993443941, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08649390174729868, \"functional effect\": 0.0333, \"times_seen\": 29.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.24255505316504591, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.07390046708752446, \"functional effect\": 0.059, \"times_seen\": 252.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.3870534953295131, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.11433474881353017, \"functional effect\": -0.0759, \"times_seen\": 60.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.12314507875313911, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09522125311031426, \"functional effect\": 0.0457, \"times_seen\": 82.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.10821930226487807, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.0811122173645204, \"functional effect\": -0.2209, \"times_seen\": 95.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.10405899190976069, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09396982278779403, \"functional effect\": 0.1373, \"times_seen\": 192.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.5018963623655844, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.06174157019905096, \"functional effect\": -0.0554, \"times_seen\": 193.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04087070854798028, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08498851105562974, \"functional effect\": 0.0006, \"times_seen\": 57.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.07170984687021514, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09188621130313249, \"functional effect\": 0.0778, \"times_seen\": 30.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.11624604608719208, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.0806621852024957, \"functional effect\": -0.0148, \"times_seen\": 128.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0056477897970153455, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08777355411370044, \"functional effect\": 0.0204, \"times_seen\": 32.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.7296730584786364, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.05272420650110502, \"functional effect\": 0.0226, \"times_seen\": 225.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.47010735265971915, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.12110998331401795, \"functional effect\": 0.0158, \"times_seen\": 155.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05563634556295079, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09086816099675576, \"functional effect\": -0.0104, \"times_seen\": 33.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.13387887340214932, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.07968232053764578, \"functional effect\": 0.0699, \"times_seen\": 136.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00032918566485984373, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08741066720247, \"functional effect\": -0.0119, \"times_seen\": 192.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.10577972005113116, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09408196913988978, \"functional effect\": -0.0334, \"times_seen\": 127.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.6251957993114955, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.1348547408302715, \"functional effect\": 0.0193, \"times_seen\": 151.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0007190782860301695, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.0873870474017584, \"functional effect\": -0.1933, \"times_seen\": 40.0}, {\"site\": 78, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02134322244903456, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08873367734183316, \"functional effect\": -0.079, \"times_seen\": 196.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.06712346966661908, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08345595903045708, \"functional effect\": 0.0751, \"times_seen\": 11.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.11853490199718236, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.0949174562967979, \"functional effect\": 0.1318, \"times_seen\": 47.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0545902746287161, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08418412840742964, \"functional effect\": -1.455, \"times_seen\": 1.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005589549515890736, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08709253021974145, \"functional effect\": -1.0138, \"times_seen\": 1.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.06796741486985969, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.09164816219783943, \"functional effect\": -0.2249, \"times_seen\": 29.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005513357074808372, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08709712992204799, \"functional effect\": 0.1303, \"times_seen\": 15.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06123628709932424, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08379721222669076, \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.03702354226968319, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08521544832455168, \"functional effect\": -0.0202, \"times_seen\": 51.0}, {\"site\": 79, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.16811569046436411, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.0982361640146373, \"functional effect\": -0.0555, \"times_seen\": 17.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.008031864146117477, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08694521743922992, \"functional effect\": -0.752, \"times_seen\": 2.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.2700993219750465, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.07250292574883899, \"functional effect\": -0.0307, \"times_seen\": 60.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0889751565692723, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.0822014236113526, \"functional effect\": -0.2553, \"times_seen\": 53.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.06192375104077985, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.09126503747613665, \"functional effect\": 0.0107, \"times_seen\": 9.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0032801028393103218, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08723205840985632, \"functional effect\": -0.2198, \"times_seen\": 14.0}, {\"site\": 80, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.09511912740167468, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08185209873522649, \"functional effect\": -0.1073, \"times_seen\": 16.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.033344620211252826, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.0854330279535184, \"functional effect\": 0.0657, \"times_seen\": 15.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04076362294908514, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08499481965385977, \"functional effect\": -0.4, \"times_seen\": 12.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.00926169742260802, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08799369983723399, \"functional effect\": 0.1143, \"times_seen\": 33.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.3310051826319221, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.10997805092018159, \"functional effect\": 0.14, \"times_seen\": 34.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -2.802295868229026, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.012533963247116075, \"functional effect\": -0.051, \"times_seen\": 33.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.012164394686293292, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08817092107113109, \"functional effect\": -0.0638, \"times_seen\": 5.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08152162674523034, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08262720742212848, \"functional effect\": -0.0464, \"times_seen\": 13.0}, {\"site\": 81, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.06582626795823739, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.09151224530003851, \"functional effect\": 0.2581, \"times_seen\": 24.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.012021714957253824, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08816220156998027, \"functional effect\": -0.0035, \"times_seen\": 10.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.07441025845745441, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08303550096725189, \"functional effect\": -0.9968, \"times_seen\": 19.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.030792606778073217, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08558428596586846, \"functional effect\": -0.0575, \"times_seen\": 27.0}, {\"site\": 82, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.11565631585654605, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08069516421152546, \"functional effect\": -0.1762, \"times_seen\": 21.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.06456451317434744, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.09143224534682444, \"functional effect\": -0.4579, \"times_seen\": 22.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0372542895613611, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.08520181989931298, \"functional effect\": -0.164, \"times_seen\": 98.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.04709816417821916, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.08462244510478278, \"functional effect\": -0.1271, \"times_seen\": 19.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006793435173465499, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.08701988443504531, \"functional effect\": -0.2285, \"times_seen\": 2.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.12520817521801145, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.09535751972049836, \"functional effect\": 0.0082, \"times_seen\": 51.0}, {\"site\": 83, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.3944464249002506, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.11492214820715864, \"functional effect\": -0.0122, \"times_seen\": 22.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.002404058560661526, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08728504421082132, \"functional effect\": -3.0402, \"times_seen\": 1.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03484545205949722, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.0853441984123107, \"functional effect\": -0.6218, \"times_seen\": 21.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.08617620248375052, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.09281221808124299, \"functional effect\": -0.7148, \"times_seen\": 39.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.026394670422627452, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08904491372952568, \"functional effect\": -2.3934, \"times_seen\": 2.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03132863166613997, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08934996522549488, \"functional effect\": -0.7449, \"times_seen\": 7.0}, {\"site\": 84, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.020825421203920527, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08617761159936337, \"functional effect\": -0.0766, \"times_seen\": 22.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.02937737817462224, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08566828206566382, \"functional effect\": -2.4263, \"times_seen\": 6.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.05031412743846801, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08443402026758383, \"functional effect\": -0.136, \"times_seen\": 9.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.02110791449287691, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08871920578895201, \"functional effect\": -0.1528, \"times_seen\": 24.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.018305410764030743, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08854703179461247, \"functional effect\": 0.0457, \"times_seen\": 23.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.016532385312180403, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08843827720370172, \"functional effect\": -0.0667, \"times_seen\": 19.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.46669418746220154, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.12082379685395107, \"functional effect\": 0.0785, \"times_seen\": 42.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -2.5274238794562263, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.015164675812698493, \"functional effect\": -0.2563, \"times_seen\": 13.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02890003277964602, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08569663187260995, \"functional effect\": -0.0829, \"times_seen\": 48.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07816308378373454, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.09229814288182968, \"functional effect\": -0.0264, \"times_seen\": 17.0}, {\"site\": 85, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.9815730398791338, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.04427724616873055, \"functional effect\": 0.1479, \"times_seen\": 24.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.09328736017490614, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.09327082615660744, \"functional effect\": -2.9525, \"times_seen\": 4.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.009979965894267619, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08682789269678452, \"functional effect\": -0.1467, \"times_seen\": 17.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -1.8519052002653646, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.024220578703796142, \"functional effect\": 0.0335, \"times_seen\": 81.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.028210940956256828, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08573757396497798, \"functional effect\": 0.2801, \"times_seen\": 20.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06570429472212445, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.0835380948080329, \"functional effect\": -0.1553, \"times_seen\": 54.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0048873303433494605, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.0877272999585488, \"functional effect\": -0.1074, \"times_seen\": 13.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.1354324725636279, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.07959655899319135, \"functional effect\": -0.2114, \"times_seen\": 73.0}, {\"site\": 86, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01692430079549567, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08846230517733832, \"functional effect\": -0.4421, \"times_seen\": 58.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.012247392206343216, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08817599364578169, \"functional effect\": -2.9064, \"times_seen\": 4.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.031051222150678542, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08556894562872568, \"functional effect\": -2.258, \"times_seen\": 7.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0006145808378442242, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08739337725936666, \"functional effect\": -2.881, \"times_seen\": 1.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03183102606954909, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08938108527374967, \"functional effect\": -1.9767, \"times_seen\": 8.0}, {\"site\": 87, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.013151031224818064, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08663725327770859, \"functional effect\": -2.8347, \"times_seen\": 3.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008724276389130368, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.0869034986512218, \"functional effect\": -2.6703, \"times_seen\": 2.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.012527235429562255, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.0866747217920403, \"functional effect\": -0.0255, \"times_seen\": 15.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.013974045216950892, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08658784343346748, \"functional effect\": -0.2364, \"times_seen\": 12.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.01016766111121694, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08681659708710529, \"functional effect\": -3.1398, \"times_seen\": 2.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.013254905426938187, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08823759329396556, \"functional effect\": -0.4407, \"times_seen\": 76.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03547813013293476, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08530677985628504, \"functional effect\": -0.0555, \"times_seen\": 101.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.02452161761618648, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08892938161875258, \"functional effect\": -0.183, \"times_seen\": 33.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.018191030067950496, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.0885400118289469, \"functional effect\": -0.0793, \"times_seen\": 12.0}, {\"site\": 88, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004924446574638202, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08713269037185929, \"functional effect\": -2.9475, \"times_seen\": 2.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.057436464477073734, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08401821127912272, \"functional effect\": -0.2771, \"times_seen\": 20.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0022539792155631694, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08729412469095413, \"functional effect\": -3.0231, \"times_seen\": 5.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010198530729372978, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08681473947586123, \"functional effect\": -2.8708, \"times_seen\": 1.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.01850931480614324, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08855954751911528, \"functional effect\": -3.114, \"times_seen\": 2.0}, {\"site\": 89, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01993594981190042, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08623075945965186, \"functional effect\": -0.3614, \"times_seen\": 17.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.024522358112442192, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08892942726380516, \"functional effect\": -0.1833, \"times_seen\": 15.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06671445385935025, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08347962282959129, \"functional effect\": -0.3369, \"times_seen\": 24.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.027500572386942167, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08577980068168715, \"functional effect\": -0.6505, \"times_seen\": 6.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.002831658326259609, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08760238781089535, \"functional effect\": -0.2806, \"times_seen\": 12.0}, {\"site\": 90, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.030106666935015944, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08562498731178746, \"functional effect\": -0.0885, \"times_seen\": 10.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.000760269866864328, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08738455237742017, \"functional effect\": -0.5236, \"times_seen\": 17.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0024248946515611296, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08728378360762332, \"functional effect\": -2.5734, \"times_seen\": 1.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.081870845431196, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.09253565645042275, \"functional effect\": -2.5408, \"times_seen\": 5.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.037501481385321604, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08518722264316661, \"functional effect\": -0.2054, \"times_seen\": 10.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.009927316116822732, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08683106145560994, \"functional effect\": -2.4163, \"times_seen\": 2.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06536184823077583, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08355792624996594, \"functional effect\": -0.2226, \"times_seen\": 67.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05233023318849465, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08431610967584861, \"functional effect\": -0.5812, \"times_seen\": 29.0}, {\"site\": 91, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.1039867208378324, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08135053395642672, \"functional effect\": -0.9631, \"times_seen\": 56.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.6947310165103163, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.0540167754260838, \"functional effect\": -0.0349, \"times_seen\": 73.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0233019341541226, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08602980704414515, \"functional effect\": -0.2343, \"times_seen\": 26.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.006518820918110325, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08782656364047174, \"functional effect\": -0.3526, \"times_seen\": 48.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.004326406009862455, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.0876931979405077, \"functional effect\": 0.1911, \"times_seen\": 21.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009232989877211469, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08687286072203325, \"functional effect\": -0.2027, \"times_seen\": 6.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.107627651374828, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.09420255485350998, \"functional effect\": -0.3224, \"times_seen\": 13.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0005781190120640661, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08739558601608458, \"functional effect\": -0.155, \"times_seen\": 42.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01909527714471972, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08628102161863391, \"functional effect\": -2.3846, \"times_seen\": 6.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.032672871332816315, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08547281661435062, \"functional effect\": -0.2821, \"times_seen\": 6.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010707210897028344, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08678413484318566, \"functional effect\": -0.0316, \"times_seen\": 29.0}, {\"site\": 92, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.017952882139738724, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08634937011964612, \"functional effect\": -0.5048, \"times_seen\": 16.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.011062086638925994, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08676279020979948, \"functional effect\": -3.0486, \"times_seen\": 3.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.49903472062874926, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.12356285936666285, \"functional effect\": -0.1267, \"times_seen\": 107.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.09002027603425508, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08214189668757282, \"functional effect\": -0.1959, \"times_seen\": 45.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.5192746549769286, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.12530857091742678, \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"E\", \"log2 fold change IC90\": -1.9350675408931057, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.02286389181581728, \"functional effect\": -0.4635, \"times_seen\": 27.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0421850405213636, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.09002486784926564, \"functional effect\": -0.224, \"times_seen\": 76.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.04251980306802652, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08489141914655718, \"functional effect\": -0.5816, \"times_seen\": 36.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06980039767264877, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08330124964926586, \"functional effect\": -0.2237, \"times_seen\": 50.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012823041995402538, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.0866569520466829, \"functional effect\": -0.1445, \"times_seen\": 30.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0673287378754403, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08344408567115406, \"functional effect\": -0.0639, \"times_seen\": 116.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.010971694205890135, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08676822652529241, \"functional effect\": -0.0785, \"times_seen\": 50.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.8071610853675721, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.15298301930234795, \"functional effect\": -0.3256, \"times_seen\": 48.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.5652511189792722, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.059088911271728856, \"functional effect\": -0.8856, \"times_seen\": 65.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.10958763377193709, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.09433062129833059, \"functional effect\": -0.2541, \"times_seen\": 19.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.08685848686912251, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.09285612154075128, \"functional effect\": -0.1713, \"times_seen\": 73.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.15327308898891814, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.07861831520865772, \"functional effect\": -0.112, \"times_seen\": 173.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0011444231365480076, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08749999650068563, \"functional effect\": -0.1663, \"times_seen\": 146.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0007857349332320014, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.0874782446304606, \"functional effect\": 0.1071, \"times_seen\": 81.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0703343385088403, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.09179864600666059, \"functional effect\": -0.1706, \"times_seen\": 20.0}, {\"site\": 93, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.010821951781428852, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08808891526154622, \"functional effect\": -0.2847, \"times_seen\": 33.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005643678766004649, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08708926260962253, \"functional effect\": -2.3838, \"times_seen\": 1.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.5355694677440284, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.06031718369119738, \"functional effect\": -0.0316, \"times_seen\": 46.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.24692471680349182, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.10375171311889556, \"functional effect\": -0.0467, \"times_seen\": 99.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.043812215428312366, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.0848154047512948, \"functional effect\": -0.1099, \"times_seen\": 9.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.09891093332543859, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08163725099874568, \"functional effect\": -0.3729, \"times_seen\": 43.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0005714410143059099, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08746525181967471, \"functional effect\": -0.3496, \"times_seen\": 18.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03441666551539544, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08536956751773848, \"functional effect\": -0.5903, \"times_seen\": 11.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010152925905222739, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08804807495962398, \"functional effect\": -0.0732, \"times_seen\": 58.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05565645472072708, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08412193765895132, \"functional effect\": -0.3448, \"times_seen\": 69.0}, {\"site\": 94, \"wildtype\": \"E\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.054019713017700886, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.09076639440902828, \"functional effect\": -0.3054, \"times_seen\": 13.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.06181099695659428, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08376383754146849, \"functional effect\": 0.0891, \"times_seen\": 71.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.017310788067130968, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08638780981562519, \"functional effect\": -0.124, \"times_seen\": 10.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.46032020655243555, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.12029116188931348, \"functional effect\": 0.0141, \"times_seen\": 20.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.08986220790406885, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08215089701471806, \"functional effect\": 0.0086, \"times_seen\": 76.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02504076834743163, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08896138842536665, \"functional effect\": 0.0609, \"times_seen\": 23.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.3148575909933769, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.10875396740363952, \"functional effect\": 0.0146, \"times_seen\": 65.0}, {\"site\": 95, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 2.65967616583088, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.5524663548005728, \"functional effect\": 0.2037, \"times_seen\": 7.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.12661309221727823, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.0954504254618365, \"functional effect\": -2.5427, \"times_seen\": 6.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.12585310368762698, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09540015695530904, \"functional effect\": 0.0308, \"times_seen\": 172.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.12360815135654837, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08025161272692917, \"functional effect\": -0.1456, \"times_seen\": 77.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.09927098463812879, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08161687945035906, \"functional effect\": 0.0324, \"times_seen\": 60.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.042178246152954034, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08491151950248152, \"functional effect\": 0.0439, \"times_seen\": 46.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04770768456060371, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08458670074480927, \"functional effect\": -0.1165, \"times_seen\": 204.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.16394367597108203, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.07803897668192736, \"functional effect\": -0.0492, \"times_seen\": 122.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.17474348350415025, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09868850272903053, \"functional effect\": -0.0515, \"times_seen\": 88.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.23806353975370584, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.10311641276966314, \"functional effect\": -0.0559, \"times_seen\": 133.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.22139047709606777, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.1019315678506542, \"functional effect\": -0.0309, \"times_seen\": 59.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.2601363653306237, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.07300534893242017, \"functional effect\": -0.0364, \"times_seen\": 168.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.5675760657000201, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.058993764389553435, \"functional effect\": 0.0211, \"times_seen\": 43.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.10111865071585864, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08151241924853204, \"functional effect\": -0.074, \"times_seen\": 150.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.016766861602638797, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08642038598286723, \"functional effect\": -0.1268, \"times_seen\": 162.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06971361922226015, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08330626038997342, \"functional effect\": -0.0761, \"times_seen\": 70.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.4606267636164696, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.1203167251736783, \"functional effect\": -0.0237, \"times_seen\": 304.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07430710046379058, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09205178111145158, \"functional effect\": -0.0523, \"times_seen\": 182.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.13092171039163034, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.07984581681661676, \"functional effect\": -0.0558, \"times_seen\": 130.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.04155248025909588, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08998540443530921, \"functional effect\": -0.083, \"times_seen\": 60.0}, {\"site\": 96, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04691740240569271, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08463304849708891, \"functional effect\": -0.001, \"times_seen\": 111.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.16749313611260114, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.07784721351509967, \"functional effect\": -0.0318, \"times_seen\": 88.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.001284704101580396, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.08735279298185024, \"functional effect\": -0.3138, \"times_seen\": 1.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.378748025985223, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.06724329919850688, \"functional effect\": 0.0587, \"times_seen\": 54.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0601304789633469, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.09115166537451794, \"functional effect\": -0.0383, \"times_seen\": 94.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.016773129683051096, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.08642001051283614, \"functional effect\": -0.0293, \"times_seen\": 39.0}, {\"site\": 97, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.12083063451982541, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.09506861683403503, \"functional effect\": -0.0632, \"times_seen\": 47.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004338488750354621, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08716808693868221, \"functional effect\": -0.4301, \"times_seen\": 1.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.09358279447476171, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08193930985859489, \"functional effect\": 0.0559, \"times_seen\": 57.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.018202695583710793, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08854072775923708, \"functional effect\": -0.1329, \"times_seen\": 25.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.005466866624454456, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08776254743957658, \"functional effect\": -0.0736, \"times_seen\": 64.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03134527834376857, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08935099620474292, \"functional effect\": 0.031, \"times_seen\": 28.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.001469136178871163, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08751969268521921, \"functional effect\": -0.185, \"times_seen\": 23.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005694929256453471, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08708616889402958, \"functional effect\": -0.1495, \"times_seen\": 1.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0511642730665137, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.0843842799788645, \"functional effect\": 0.0456, \"times_seen\": 125.0}, {\"site\": 98, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.17051907175722325, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.0776841064207451, \"functional effect\": 0.0125, \"times_seen\": 75.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.119999380053736, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.09501385581543248, \"functional effect\": 0.0312, \"times_seen\": 14.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05319839325484865, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.08426538664898885, \"functional effect\": 0.0773, \"times_seen\": 19.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.17393767104412616, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.07750024467286461, \"functional effect\": -0.134, \"times_seen\": 38.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.009457452160857029, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.08800564023479496, \"functional effect\": -0.1162, \"times_seen\": 1.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.004414880501835921, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.08769857596484684, \"functional effect\": -0.0282, \"times_seen\": 88.0}, {\"site\": 99, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.5056728955121995, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.12413271077842199, \"functional effect\": -0.0332, \"times_seen\": 42.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.012091354014004286, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08670091277984568, \"functional effect\": 0.3679, \"times_seen\": 10.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.005636250630126852, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.0877728520736919, \"functional effect\": 0.0811, \"times_seen\": 72.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.046252031986757064, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08467209023005856, \"functional effect\": 0.0793, \"times_seen\": 77.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.4380733688410162, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.11845046072243953, \"functional effect\": -0.0588, \"times_seen\": 85.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.014309267344399119, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08830210336696058, \"functional effect\": 0.1373, \"times_seen\": 5.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06907204881952085, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08334331514877638, \"functional effect\": 0.0496, \"times_seen\": 74.0}, {\"site\": 100, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0006020832165756465, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08746710956252711, \"functional effect\": 0.0622, \"times_seen\": 21.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.055901122325413666, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.08410767257363955, \"functional effect\": -1.257, \"times_seen\": 28.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03718353568934958, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.0852059985415872, \"functional effect\": -2.2717, \"times_seen\": 3.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.23316904917193224, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.10276717253727143, \"functional effect\": -1.2139, \"times_seen\": 21.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.7168062376403448, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.026598267883686733, \"functional effect\": -1.7102, \"times_seen\": 11.0}, {\"site\": 101, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.10263527688518599, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.08142677473744461, \"functional effect\": -0.5601, \"times_seen\": 31.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.0289947769362837, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08920554020558343, \"functional effect\": -2.5166, \"times_seen\": 3.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005272202537480107, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08711168991083869, \"functional effect\": -1.8512, \"times_seen\": 2.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.12955717655412846, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.07992137253475594, \"functional effect\": -0.187, \"times_seen\": 24.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.004120795718491151, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08718124101236281, \"functional effect\": -1.3353, \"times_seen\": 9.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.2694686730319864, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.21077139944858284, \"functional effect\": -0.3178, \"times_seen\": 35.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0005190836179698204, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08739916233559793, \"functional effect\": -2.3409, \"times_seen\": 5.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04769984556695147, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.09036965291253642, \"functional effect\": -1.9068, \"times_seen\": 8.0}, {\"site\": 102, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.028764128387553774, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08570470502522276, \"functional effect\": -0.35, \"times_seen\": 23.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.17908829479855418, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.07722405124151706, \"functional effect\": -0.1699, \"times_seen\": 44.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 1.6650376086576781, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.27726164403413944, \"functional effect\": -0.5794, \"times_seen\": 5.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0027932811059653284, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.0876000575253361, \"functional effect\": 0.1526, \"times_seen\": 1.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.014176909258508525, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08657566877115748, \"functional effect\": -0.1673, \"times_seen\": 106.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03094452352363508, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08557527435821222, \"functional effect\": -0.0713, \"times_seen\": 54.0}, {\"site\": 103, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010153855481267751, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.086817427868049, \"functional effect\": -0.1562, \"times_seen\": 27.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05565839845952394, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.0908695500092742, \"functional effect\": -1.1841, \"times_seen\": 28.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.020083472917320835, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.08865622963746196, \"functional effect\": -0.2396, \"times_seen\": 57.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.08759609599956758, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.08228003685700701, \"functional effect\": -1.1602, \"times_seen\": 22.0}, {\"site\": 104, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.4068544766888049, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.11591481096934736, \"functional effect\": -0.067, \"times_seen\": 45.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04901204667493305, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08451025920763942, \"functional effect\": -2.0577, \"times_seen\": 11.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.026106281116285185, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08586274256278774, \"functional effect\": -2.5776, \"times_seen\": 3.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03178780929523306, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.0893784078511303, \"functional effect\": -1.6558, \"times_seen\": 9.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03768448792083304, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.0851764172897843, \"functional effect\": -2.156, \"times_seen\": 10.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03172007913680389, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08552928366251597, \"functional effect\": -1.5646, \"times_seen\": 4.0}, {\"site\": 105, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.7286682148154202, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.026380470971326467, \"functional effect\": -2.9922, \"times_seen\": 5.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004193484031132098, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08717684860961378, \"functional effect\": -0.7745, \"times_seen\": 7.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.022678843172364835, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08606697080556447, \"functional effect\": -0.0697, \"times_seen\": 42.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.01566531159190283, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08838514091016228, \"functional effect\": -0.4085, \"times_seen\": 4.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0013717804653077214, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08734752081149151, \"functional effect\": -2.001, \"times_seen\": 1.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.4947195959977824, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.12319383297612536, \"functional effect\": -0.3128, \"times_seen\": 90.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0026492107423883213, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08727021342506082, \"functional effect\": -0.2263, \"times_seen\": 4.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.1347644631809535, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.07963342302788964, \"functional effect\": 0.3447, \"times_seen\": 47.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.022316482488276414, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.086088590900253, \"functional effect\": 0.152, \"times_seen\": 31.0}, {\"site\": 106, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.3268727798876501, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.10966348455734415, \"functional effect\": -0.0787, \"times_seen\": 44.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.9847160957774874, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.022090444372847434, \"functional effect\": -1.0708, \"times_seen\": 45.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.057931412470305574, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.083989391943473, \"functional effect\": -0.2012, \"times_seen\": 14.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.021322952893468406, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.0861478972805692, \"functional effect\": -0.2797, \"times_seen\": 2.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -2.490563609850738, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.015557119126981276, \"functional effect\": -0.137, \"times_seen\": 39.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.025886141063526602, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.0858758453116884, \"functional effect\": -0.5204, \"times_seen\": 7.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05031045422317883, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.0844342352435283, \"functional effect\": 0.1497, \"times_seen\": 8.0}, {\"site\": 107, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0007883409233814092, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08747840264559423, \"functional effect\": 0.1351, \"times_seen\": 8.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.024436790054335033, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08596216070039703, \"functional effect\": -0.373, \"times_seen\": 17.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.808657136512095, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.024957637932984226, \"functional effect\": -0.0224, \"times_seen\": 17.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.053448788484821555, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08425076275458213, \"functional effect\": -1.5686, \"times_seen\": 8.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.1424005083074185, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.039606522262525, \"functional effect\": -0.6082, \"times_seen\": 61.0}, {\"site\": 108, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.046207993162487235, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08467467491781969, \"functional effect\": -0.4187, \"times_seen\": 13.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.046345207472134824, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.09028483892492056, \"functional effect\": -0.2564, \"times_seen\": 38.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.24463272365381394, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.07379411729855397, \"functional effect\": -0.2263, \"times_seen\": 77.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.21549480549298736, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.07529967982826677, \"functional effect\": -0.2835, \"times_seen\": 160.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03532596447108777, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08959787403170201, \"functional effect\": -1.4678, \"times_seen\": 13.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0649559397478368, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08358143894107312, \"functional effect\": -0.0352, \"times_seen\": 122.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.022483855857979573, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.0888038603086064, \"functional effect\": -1.9815, \"times_seen\": 12.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.16916134859056578, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.09830739090269407, \"functional effect\": -0.1555, \"times_seen\": 16.0}, {\"site\": 109, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0028104059767564095, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08726046309235744, \"functional effect\": -0.9627, \"times_seen\": 4.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.2665398683896086, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.07268202764706606, \"functional effect\": -0.1061, \"times_seen\": 30.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.7147417683847291, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.14349020015791739, \"functional effect\": -0.0792, \"times_seen\": 51.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.01195833356891399, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.0867089072106741, \"functional effect\": -0.1917, \"times_seen\": 2.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.009037721668929253, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08688461972545018, \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02095117575803562, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08617010013331763, \"functional effect\": 0.2182, \"times_seen\": 7.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.027073034368708664, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08908679303245182, \"functional effect\": 0.0034, \"times_seen\": 23.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -3.5265873745154814, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.007586735580217565, \"functional effect\": -0.126, \"times_seen\": 61.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.08198841902944408, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08260047723817444, \"functional effect\": 0.0271, \"times_seen\": 41.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02234280903852032, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08608701995499383, \"functional effect\": 0.0242, \"times_seen\": 59.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01407717128677003, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08658165422189053, \"functional effect\": -0.2199, \"times_seen\": 113.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.07337897806235391, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08309487837935202, \"functional effect\": -0.0148, \"times_seen\": 20.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.08030227096670932, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08269707288184261, \"functional effect\": -0.0657, \"times_seen\": 25.0}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 110, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.10182866686358377, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08147231313247576, \"functional effect\": -0.069, \"times_seen\": 39.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.051039835406596866, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08439155874180906, \"functional effect\": -0.4226, \"times_seen\": 39.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.008880851847926285, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08797047414688507, \"functional effect\": -0.2109, \"times_seen\": 30.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.06453002359265073, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08360611771198077, \"functional effect\": -0.2066, \"times_seen\": 55.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.015637916375704188, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08838346258800389, \"functional effect\": -0.0809, \"times_seen\": 8.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.052342359893794564, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.09066092594907686, \"functional effect\": -0.3784, \"times_seen\": 24.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.07437429851500195, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.09205606881203095, \"functional effect\": 0.0556, \"times_seen\": 60.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.042159927827498785, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08491259765599285, \"functional effect\": -0.0779, \"times_seen\": 12.0}, {\"site\": 111, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.007371843562024227, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08787850822901636, \"functional effect\": 0.0329, \"times_seen\": 8.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.08284004398831087, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.09259784253558181, \"functional effect\": -0.3857, \"times_seen\": 8.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05021570203567542, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.09052738231758169, \"functional effect\": -2.572, \"times_seen\": 4.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.00902404795323782, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.08688544321287092, \"functional effect\": -1.8954, \"times_seen\": 2.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.012927947081697283, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.08665065104455337, \"functional effect\": -1.9387, \"times_seen\": 4.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.018607304570346036, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.08856556280553983, \"functional effect\": 0.1233, \"times_seen\": 11.0}, {\"site\": 112, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0076541324797353575, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08696798473288006, \"functional effect\": -2.592, \"times_seen\": 2.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03365653239213078, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08949425472789761, \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.05779311637019628, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.09100410681818676, \"functional effect\": -1.5896, \"times_seen\": 12.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.02274621878826648, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08882001130309786, \"functional effect\": -0.535, \"times_seen\": 10.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.009822343219492047, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08683737965831873, \"functional effect\": -0.6093, \"times_seen\": 18.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.012360878975872269, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.088182930109815, \"functional effect\": -1.4123, \"times_seen\": 17.0}, {\"site\": 113, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.015993295695005648, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08840523678336204, \"functional effect\": -0.7012, \"times_seen\": 3.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.020992724955927335, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08871212243732585, \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0034955168406165847, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08721903444886316, \"functional effect\": -2.1498, \"times_seen\": 1.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.010852493837284987, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08809078013594615, \"functional effect\": -2.2258, \"times_seen\": 2.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004073825842398053, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08718407942147315, \"functional effect\": -3.132, \"times_seen\": 1.0}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 114, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.023493390610582966, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08886602310441354, \"functional effect\": -2.842, \"times_seen\": 2.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.019722211227546083, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08863403223002903, \"functional effect\": -0.4963, \"times_seen\": 9.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0037373898843266052, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08765740231952973, \"functional effect\": 0.0261, \"times_seen\": 9.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.007646251139677201, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08696845983407236, \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.029835183143062376, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08925751981833349, \"functional effect\": -2.7012, \"times_seen\": 2.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0004676711532444687, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08745896086395497, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.015618015359911424, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08838224340549933, \"functional effect\": -1.1639, \"times_seen\": 5.0}, {\"site\": 115, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.013750688310876143, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08660124993272288, \"functional effect\": -1.6211, \"times_seen\": 4.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.06168814784360751, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.09125013441044548, \"functional effect\": -0.2045, \"times_seen\": 40.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.3447666202760116, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.06884595612662606, \"functional effect\": -0.0168, \"times_seen\": 75.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.06555623601205707, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.08354666846836989, \"functional effect\": -0.0479, \"times_seen\": 32.0}, {\"site\": 116, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 1.4631713532092412, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.24105824814953442, \"functional effect\": -0.0866, \"times_seen\": 12.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.009775809558950145, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.08684018061500179, \"functional effect\": -2.9694, \"times_seen\": 2.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.024281641554805396, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.08597140563229655, \"functional effect\": -0.0081, \"times_seen\": 16.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.007866724973663603, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.08695517025852594, \"functional effect\": -1.8059, \"times_seen\": 1.0}, {\"site\": 117, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.22032375314756686, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.07504806023149765, \"functional effect\": -0.2743, \"times_seen\": 33.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0012026094758311597, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.08735776381676838, \"functional effect\": -2.935, \"times_seen\": 1.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.4718114618259367, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.12125312276168024, \"functional effect\": -0.2152, \"times_seen\": 10.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.2390703417943107, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.1031883989105556, \"functional effect\": -0.0109, \"times_seen\": 45.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.14447436477158146, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.07909925854560214, \"functional effect\": -0.0259, \"times_seen\": 63.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.022302064493851498, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.08879267100153404, \"functional effect\": -0.0043, \"times_seen\": 28.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0008271085242275251, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.08748075336647841, \"functional effect\": -0.0183, \"times_seen\": 7.0}, {\"site\": 118, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.0006108645547222567, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.08746764195543175, \"functional effect\": -1.5307, \"times_seen\": 3.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.010665959016697098, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.088079391079249, \"functional effect\": 0.0972, \"times_seen\": 10.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02189903936836033, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.08611350419699784, \"functional effect\": -0.5188, \"times_seen\": 9.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.28479651326653077, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.0717680649672906, \"functional effect\": -0.6765, \"times_seen\": 19.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04250078185898829, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.08489253840463194, \"functional effect\": -0.1782, \"times_seen\": 49.0}, {\"site\": 119, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 1.5879017746567101, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.2628267678584837, \"functional effect\": -0.2585, \"times_seen\": 15.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0006954296558048323, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08738847986035132, \"functional effect\": -2.2739, \"times_seen\": 6.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02147697335811933, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08613870072097064, \"functional effect\": -0.1638, \"times_seen\": 23.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0420349172422194, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08491995571375323, \"functional effect\": -0.2587, \"times_seen\": 15.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.004645295870608922, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08771258357760679, \"functional effect\": -0.2652, \"times_seen\": 16.0}, {\"site\": 120, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01353310487893125, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08661431188804525, \"functional effect\": -0.1114, \"times_seen\": 9.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.029657821028220878, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08565163078326365, \"functional effect\": -2.2622, \"times_seen\": 1.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0998333921002686, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08158506884943656, \"functional effect\": -0.0998, \"times_seen\": 19.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.008649969923837878, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08690797475873151, \"functional effect\": -0.2161, \"times_seen\": 1.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.007356210868522522, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08698594578272185, \"functional effect\": -0.112, \"times_seen\": 3.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.010124045218780279, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08681922178636048, \"functional effect\": -0.0756, \"times_seen\": 1.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.3215226676322465, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.03498207503999377, \"functional effect\": 0.0374, \"times_seen\": 30.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08247981164219698, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08257234769488409, \"functional effect\": -0.2843, \"times_seen\": 47.0}, {\"site\": 121, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.015031171351288158, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08652441995018706, \"functional effect\": -0.024, \"times_seen\": 84.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.08734092626509563, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.0928871779601062, \"functional effect\": -1.2814, \"times_seen\": 6.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0162423030671736, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08645181382603065, \"functional effect\": -0.1718, \"times_seen\": 7.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.06388935407605573, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.0836432536170343, \"functional effect\": -0.3737, \"times_seen\": 54.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.009986063458942972, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08803789188755465, \"functional effect\": -0.3962, \"times_seen\": 10.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0006813190827872752, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08747191357329724, \"functional effect\": -0.439, \"times_seen\": 11.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.004921893298928604, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08713284457907038, \"functional effect\": -0.0765, \"times_seen\": 14.0}, {\"site\": 122, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.008385724810978367, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08794028822012487, \"functional effect\": -2.1196, \"times_seen\": 6.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.013133214216899896, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.0866383232378288, \"functional effect\": -0.0348, \"times_seen\": 4.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0013838406213782183, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.0875145184660693, \"functional effect\": -0.0677, \"times_seen\": 1.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03164974084291299, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08553345372644246, \"functional effect\": -0.1177, \"times_seen\": 6.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0028126465750395527, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08760123339933752, \"functional effect\": -1.3304, \"times_seen\": 1.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.008067569957320265, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08694306562542686, \"functional effect\": -0.0595, \"times_seen\": 6.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.017561863861992245, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08637277683905142, \"functional effect\": 0.0223, \"times_seen\": 8.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.5251373488235147, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.125818824633148, \"functional effect\": 0.1075, \"times_seen\": 15.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.019398442093902735, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08861414324228553, \"functional effect\": -0.1681, \"times_seen\": 11.0}, {\"site\": 123, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0003679520885056114, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08740831843621445, \"functional effect\": 0.3921, \"times_seen\": 1.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.024339150693210625, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08596797868288301, \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.005481016282273162, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08776340820090874, \"functional effect\": -0.0382, \"times_seen\": 18.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.006420886361913688, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08704235858223994, \"functional effect\": -0.1827, \"times_seen\": 1.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -1.0238453041521522, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.04299870563798664, \"functional effect\": -0.2101, \"times_seen\": 61.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.00720263835442132, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08699520578641987, \"functional effect\": -0.5421, \"times_seen\": 1.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.05150319247222878, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08436445866516602, \"functional effect\": -0.219, \"times_seen\": 27.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.07730407868789517, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.09224320335974136, \"functional effect\": -0.3493, \"times_seen\": 32.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05263144636335951, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08429850756917845, \"functional effect\": -0.0396, \"times_seen\": 13.0}, {\"site\": 124, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05966350296468161, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.09112216589568407, \"functional effect\": -0.4349, \"times_seen\": 11.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.028699235408149545, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.08570856014261383, \"functional effect\": -0.4226, \"times_seen\": 7.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.037688597060855755, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.08974472439198683, \"functional effect\": -0.106, \"times_seen\": 35.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.014983228814145171, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.08834336372798214, \"functional effect\": -0.2638, \"times_seen\": 12.0}, {\"site\": 125, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008077010194009384, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08694249671764705, \"functional effect\": -2.3119, \"times_seen\": 2.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.02997765821685878, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08926633498669763, \"functional effect\": -0.2409, \"times_seen\": 12.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03623918025960217, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08526179071251333, \"functional effect\": -0.4791, \"times_seen\": 18.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.011030485875912988, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08676469068101628, \"functional effect\": -0.3778, \"times_seen\": 3.0}, {\"site\": 126, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.028308859488850924, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08573175498570883, \"functional effect\": 0.0844, \"times_seen\": 32.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.019026668171173912, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08859131084716251, \"functional effect\": -0.3373, \"times_seen\": 3.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.012084489689399788, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08670132530266429, \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.12113554428909304, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08038927234287725, \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.2385339263937775, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.07410673220567263, \"functional effect\": -0.0909, \"times_seen\": 50.0}, {\"site\": 127, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.021665543866053034, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08875350409591642, \"functional effect\": -0.2494, \"times_seen\": 9.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01564952414543694, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08838417371473554, \"functional effect\": -0.4587, \"times_seen\": 16.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.015679025434239026, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.0883859810777749, \"functional effect\": -0.4335, \"times_seen\": 29.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.061972761397197915, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08375444591655191, \"functional effect\": -0.2335, \"times_seen\": 10.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0004715744866334729, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08740204050910916, \"functional effect\": -0.1666, \"times_seen\": 23.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.024889457276608653, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08895205856930181, \"functional effect\": -0.4105, \"times_seen\": 7.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.019463321370009386, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08861812838854248, \"functional effect\": -0.8318, \"times_seen\": 10.0}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 128, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027442395053130366, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08578325986091725, \"functional effect\": -0.3397, \"times_seen\": 9.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005006266109032373, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08712774895749197, \"functional effect\": -2.8472, \"times_seen\": 1.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02254519898408822, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08880763631258685, \"functional effect\": -2.2664, \"times_seen\": 2.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.009785611420400655, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08683959061330147, \"functional effect\": -1.8136, \"times_seen\": 3.0}, {\"site\": 129, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.021700881391401278, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08612533292673533, \"functional effect\": -2.3392, \"times_seen\": 2.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.06178840051807708, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.09125647558970892, \"functional effect\": 0.0898, \"times_seen\": 42.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.13578693327023023, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.07957700504308485, \"functional effect\": -0.0837, \"times_seen\": 81.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.01736745504253769, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.08638441669399108, \"functional effect\": -0.2183, \"times_seen\": 15.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.1591858851089514, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.09762999257148655, \"functional effect\": 0.3539, \"times_seen\": 41.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.016564718410383303, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.08844025926883933, \"functional effect\": -0.1598, \"times_seen\": 9.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.1527466986067614, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.0786470055933379, \"functional effect\": 0.2681, \"times_seen\": 59.0}, {\"site\": 130, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.034814984833766806, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.08534600075330459, \"functional effect\": 0.3141, \"times_seen\": 16.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.002386148058602788, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.08757534000329432, \"functional effect\": -0.1434, \"times_seen\": 24.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06721519914643093, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.08345065289982986, \"functional effect\": -0.2888, \"times_seen\": 16.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.030541638616782992, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.08559917532127503, \"functional effect\": -1.5164, \"times_seen\": 8.0}, {\"site\": 131, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.18019992328037038, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.0990624608097183, \"functional effect\": -0.1178, \"times_seen\": 18.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006663990521769922, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08702769257444096, \"functional effect\": -2.8438, \"times_seen\": 1.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.21071849142681764, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.10118033582319902, \"functional effect\": 0.125, \"times_seen\": 41.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.3841439871902773, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.06699226587664571, \"functional effect\": -0.0731, \"times_seen\": 137.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.10686044505721462, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08118865198291426, \"functional effect\": -0.0553, \"times_seen\": 29.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.011652192530602842, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08672730886229321, \"functional effect\": -0.1193, \"times_seen\": 144.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.11196919126918663, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08090166222072931, \"functional effect\": 0.0087, \"times_seen\": 9.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.047540199332748785, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.09035965331029848, \"functional effect\": -0.0991, \"times_seen\": 47.0}, {\"site\": 132, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.037529696480888844, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08518555663471958, \"functional effect\": -0.0935, \"times_seen\": 10.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07135264304119955, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08321167115974808, \"functional effect\": -0.0108, \"times_seen\": 37.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.040273244284039125, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08502371469360855, \"functional effect\": -0.0847, \"times_seen\": 42.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.024223085614008547, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08597489510065931, \"functional effect\": -0.3028, \"times_seen\": 4.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0510809627186024, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.09058169267173515, \"functional effect\": -0.068, \"times_seen\": 12.0}, {\"site\": 133, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.10428208100579511, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08133388092353543, \"functional effect\": -0.0252, \"times_seen\": 26.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.06702587670314421, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.0915883698725497, \"functional effect\": -0.1883, \"times_seen\": 17.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.07666297315167904, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.09220222138585332, \"functional effect\": -0.0199, \"times_seen\": 87.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.03270695217287958, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08943536909355726, \"functional effect\": -0.1983, \"times_seen\": 13.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.2653465811920444, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.03637108477025226, \"functional effect\": -0.0987, \"times_seen\": 16.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03201573407303078, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08939252945164942, \"functional effect\": -0.0854, \"times_seen\": 15.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.049986089595604924, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08445322093178564, \"functional effect\": -0.2441, \"times_seen\": 16.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00559609181898678, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.0870921352752646, \"functional effect\": -0.1774, \"times_seen\": 6.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.027660281227158273, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08577030523474571, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 134, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06063857158843911, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08383193700854052, \"functional effect\": -0.0384, \"times_seen\": 43.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.005585132344444856, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08776974211759447, \"functional effect\": 0.1167, \"times_seen\": 7.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.05042771538975357, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08442737277135871, \"functional effect\": 0.2205, \"times_seen\": 24.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.08654399263749729, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08234006248522284, \"functional effect\": 0.0149, \"times_seen\": 18.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.029179820473602798, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08568001398905369, \"functional effect\": -0.073, \"times_seen\": 13.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0007065331642627573, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08738780728925084, \"functional effect\": -0.0814, \"times_seen\": 13.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -6.641266135949879, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.000875877184882088, \"functional effect\": -0.0079, \"times_seen\": 28.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.025318848501838676, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08590961981446081, \"functional effect\": 0.2271, \"times_seen\": 9.0}, {\"site\": 135, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0682733801740963, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.083389466357999, \"functional effect\": -0.0102, \"times_seen\": 26.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0004885959174561644, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08740100931473481, \"functional effect\": -2.988, \"times_seen\": 1.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.00536331289667395, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.0871061887297, \"functional effect\": -0.0355, \"times_seen\": 2.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.8347486103821888, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.04902066059004077, \"functional effect\": 0.0073, \"times_seen\": 185.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0722466069453633, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.0831601251394222, \"functional effect\": -0.1698, \"times_seen\": 32.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0737214711983835, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.09201442236584237, \"functional effect\": 0.0292, \"times_seen\": 71.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.07839540710098217, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.09231300724106334, \"functional effect\": -0.0714, \"times_seen\": 35.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.2827285735529145, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.07187101011110322, \"functional effect\": 0.0135, \"times_seen\": 127.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.5607092684366466, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.1289596478717589, \"functional effect\": 0.0006, \"times_seen\": 106.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.08205671812095575, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08259656691488568, \"functional effect\": -0.0646, \"times_seen\": 50.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.03942113849128326, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08507394748534741, \"functional effect\": -0.0658, \"times_seen\": 32.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.1393892131484762, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.1925989254859012, \"functional effect\": -0.0911, \"times_seen\": 81.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.11833062325672108, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08054571905796143, \"functional effect\": -0.0307, \"times_seen\": 23.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.012719058867252261, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08666319812463691, \"functional effect\": -0.0782, \"times_seen\": 125.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.6655673282385455, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.13868173294577274, \"functional effect\": -0.0112, \"times_seen\": 104.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06475596564172131, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08359302509164869, \"functional effect\": 0.099, \"times_seen\": 39.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.1183593063022998, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.0402720588491768, \"functional effect\": -0.1031, \"times_seen\": 85.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.036554794563926046, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08967422243777042, \"functional effect\": -0.0089, \"times_seen\": 115.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.016080088476165346, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08841055541755655, \"functional effect\": -0.0597, \"times_seen\": 94.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.008823553911032034, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.0868975186853214, \"functional effect\": -0.0432, \"times_seen\": 76.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.144376537873961, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.09663294125479388, \"functional effect\": -0.0004, \"times_seen\": 22.0}, {\"site\": 136, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.25688902015909804, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.07316986088676096, \"functional effect\": -0.1254, \"times_seen\": 108.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.01297379186256723, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08664789757491471, \"functional effect\": 0.0539, \"times_seen\": 7.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.010339407552174048, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08680626257172441, \"functional effect\": 0.1536, \"times_seen\": 2.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0028868288439663032, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08760573790316258, \"functional effect\": -0.1663, \"times_seen\": 14.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.2052916814211112, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.037917053411381345, \"functional effect\": -0.0056, \"times_seen\": 52.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016570182428473097, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08643216827108717, \"functional effect\": -0.0651, \"times_seen\": 13.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.037401135573404055, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08519314799680519, \"functional effect\": -0.0358, \"times_seen\": 34.0}, {\"site\": 137, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.030335773503088526, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08561139075197646, \"functional effect\": -0.1179, \"times_seen\": 16.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.06028051542913859, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08385274547165036, \"functional effect\": 0.0078, \"times_seen\": 34.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.016920452707337257, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08641118605103894, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03535853586281616, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08959989688498275, \"functional effect\": -0.0353, \"times_seen\": 20.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04232540207861803, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08490285890848341, \"functional effect\": -0.0265, \"times_seen\": 28.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.05692419079386291, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.09094931215604833, \"functional effect\": -0.134, \"times_seen\": 10.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.028659278034467987, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08918479785860467, \"functional effect\": 0.2253, \"times_seen\": 3.0}, {\"site\": 138, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0415921739730755, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08494602047965816, \"functional effect\": 0.0353, \"times_seen\": 32.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.03824680043141936, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08977945487829057, \"functional effect\": -0.0929, \"times_seen\": 18.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0005300913403406378, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08739849548500449, \"functional effect\": -0.1315, \"times_seen\": 42.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.002417351697109973, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08728423996139632, \"functional effect\": 0.191, \"times_seen\": 11.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03196948005385141, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08551449936125127, \"functional effect\": 0.1949, \"times_seen\": 25.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.021491665014534263, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08874280784551106, \"functional effect\": 0.144, \"times_seen\": 27.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010171138997959081, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08681638779968175, \"functional effect\": -0.1531, \"times_seen\": 4.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.010372949338093036, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08680424440215534, \"functional effect\": -0.2015, \"times_seen\": 2.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.021694607672367805, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08612570745309049, \"functional effect\": 0.0782, \"times_seen\": 10.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.21417889399354292, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.07536839353108254, \"functional effect\": -0.0493, \"times_seen\": 16.0}, {\"site\": 139, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.011172179370956301, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08675616955339299, \"functional effect\": 0.2301, \"times_seen\": 15.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.01948808606120625, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08861964958280577, \"functional effect\": 0.0809, \"times_seen\": 14.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.16759620213189638, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.07784165231498873, \"functional effect\": -0.0645, \"times_seen\": 145.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.23000017386201801, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.07454638340253311, \"functional effect\": -0.1518, \"times_seen\": 140.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.36574509501658065, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.11265845067076077, \"functional effect\": -0.0027, \"times_seen\": 66.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.012673530109603584, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08666593309626448, \"functional effect\": -0.0629, \"times_seen\": 32.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.6331619436455157, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.05637191557148933, \"functional effect\": -0.1234, \"times_seen\": 121.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06266663732386431, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08371417321935776, \"functional effect\": -0.1008, \"times_seen\": 77.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03020780166228874, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08928057618114804, \"functional effect\": 0.0047, \"times_seen\": 50.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.11746879017372117, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.09484734082577018, \"functional effect\": -0.3408, \"times_seen\": 40.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.6321125043026317, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.056412936318175476, \"functional effect\": 0.0144, \"times_seen\": 134.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.020320136207225777, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08620779946252902, \"functional effect\": 0.0018, \"times_seen\": 49.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0070256404648178054, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08700587949914944, \"functional effect\": -0.0348, \"times_seen\": 83.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.5877139977499917, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.131396280666111, \"functional effect\": 0.0264, \"times_seen\": 131.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.4590493073415956, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.06360275370003324, \"functional effect\": 0.0365, \"times_seen\": 41.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.3814146044083011, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.11388873435710659, \"functional effect\": -0.3689, \"times_seen\": 113.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.019009064082121663, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08628617778342908, \"functional effect\": -0.1074, \"times_seen\": 207.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.3149692521239168, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.1087623850252167, \"functional effect\": 0.0065, \"times_seen\": 93.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.6250943608730355, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.056688031618010434, \"functional effect\": -0.0163, \"times_seen\": 89.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.1343239712381868, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.09596195219889199, \"functional effect\": 0.0605, \"times_seen\": 32.0}, {\"site\": 140, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.017205344356084385, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08847953971566387, \"functional effect\": -0.1328, \"times_seen\": 82.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.01083700677275335, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08677632743013636, \"functional effect\": -0.0301, \"times_seen\": 14.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.2083463843359162, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.07567370868607164, \"functional effect\": 0.168, \"times_seen\": 10.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.005965123653267403, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.087069860532993, \"functional effect\": -0.1113, \"times_seen\": 14.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.017236085791230787, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08639228306388613, \"functional effect\": -0.0101, \"times_seen\": 33.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01741765564464864, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08638141087906773, \"functional effect\": -0.0471, \"times_seen\": 80.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.030161032880944336, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08927768196168553, \"functional effect\": 0.1253, \"times_seen\": 19.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013504483835952928, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08661603021136573, \"functional effect\": 0.0047, \"times_seen\": 46.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.045465460980662606, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08471826684275521, \"functional effect\": 0.0445, \"times_seen\": 11.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02262348680997908, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08881245558846704, \"functional effect\": -0.0282, \"times_seen\": 8.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.17069579984345587, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.09841200632332348, \"functional effect\": -0.06, \"times_seen\": 15.0}, {\"site\": 141, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0142976432492168, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.0865684238660781, \"functional effect\": -0.0143, \"times_seen\": 87.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0001312375968665432, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08742266139340475, \"functional effect\": 0.0112, \"times_seen\": 1.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.4688153092206692, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.06317366301869219, \"functional effect\": 0.0494, \"times_seen\": 76.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07239848452480456, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08315137104145486, \"functional effect\": 0.0829, \"times_seen\": 21.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0206147992459559, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08619019376106825, \"functional effect\": 0.2134, \"times_seen\": 5.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.1404348301250072, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.07932104619770458, \"functional effect\": 0.0867, \"times_seen\": 79.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.017763732234359845, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08636069201753117, \"functional effect\": 0.1616, \"times_seen\": 4.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0033298132213665198, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08763264167064706, \"functional effect\": -0.0244, \"times_seen\": 39.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.016103798743501412, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08646011393413115, \"functional effect\": 0.0635, \"times_seen\": 62.0}, {\"site\": 142, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04239079209487308, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08489901078164351, \"functional effect\": -0.0491, \"times_seen\": 11.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.01428902484572658, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.08830086440611323, \"functional effect\": -0.0551, \"times_seen\": 17.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.09064278388143648, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09310000982237064, \"functional effect\": 0.0116, \"times_seen\": 62.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.11649846240802822, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09478356985348765, \"functional effect\": -0.0741, \"times_seen\": 21.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.05722529136218391, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.08403051026501807, \"functional effect\": -0.1002, \"times_seen\": 46.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05623738082675476, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09090602509527068, \"functional effect\": -0.0122, \"times_seen\": 17.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.36114964552943296, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.11230016805881533, \"functional effect\": 0.0886, \"times_seen\": 75.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.007935040516833082, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.0879128207958185, \"functional effect\": 0.0449, \"times_seen\": 108.0}, {\"site\": 143, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.14645670071512562, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09677237282783478, \"functional effect\": 0.0044, \"times_seen\": 52.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0018243695471473222, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08732012324452082, \"functional effect\": -0.0678, \"times_seen\": 14.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004134290617888836, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08718042552707934, \"functional effect\": 0.0107, \"times_seen\": 26.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07156403250507253, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08319947954514137, \"functional effect\": -0.1116, \"times_seen\": 25.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0030962962996796835, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08724317291693132, \"functional effect\": 0.0619, \"times_seen\": 11.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.038047312217081214, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08515499891163265, \"functional effect\": -0.1299, \"times_seen\": 13.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02751573200635559, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08911413392104361, \"functional effect\": 0.0286, \"times_seen\": 21.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.033280596193647885, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08543681939030949, \"functional effect\": 0.0276, \"times_seen\": 16.0}, {\"site\": 144, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05636234613296172, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08408078798635468, \"functional effect\": -0.0154, \"times_seen\": 23.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.012032743707146633, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08816287553264045, \"functional effect\": 0.1374, \"times_seen\": 33.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.021943584938593122, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08877061062006242, \"functional effect\": 0.0949, \"times_seen\": 50.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.064549536972298, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08360498689303676, \"functional effect\": 0.0173, \"times_seen\": 53.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.10724829220801255, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08116682855232842, \"functional effect\": 0.0648, \"times_seen\": 66.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.029041282526858097, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08568824199484497, \"functional effect\": 0.1539, \"times_seen\": 11.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04102499915610018, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08497942235183646, \"functional effect\": 0.0102, \"times_seen\": 23.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.012382518005653714, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08668341661058168, \"functional effect\": 0.0316, \"times_seen\": 23.0}, {\"site\": 145, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00048410709091321235, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08740128125618447, \"functional effect\": -0.1884, \"times_seen\": 11.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.008112843823752845, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08792365617895824, \"functional effect\": 0.1256, \"times_seen\": 13.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.11491726439770446, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.09467974368928661, \"functional effect\": -0.3201, \"times_seen\": 14.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0035762461438133475, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08721415404470334, \"functional effect\": -0.7801, \"times_seen\": 1.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.01565525230127458, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08838452464082273, \"functional effect\": -0.1226, \"times_seen\": 28.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0677911685235151, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.09163696671530344, \"functional effect\": -0.2093, \"times_seen\": 34.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.018126995747605543, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08633894955761229, \"functional effect\": -0.205, \"times_seen\": 6.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 1.0830285886387216, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.18521988972737244, \"functional effect\": -0.0894, \"times_seen\": 44.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.016632830217577558, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08642841511014064, \"functional effect\": -0.3216, \"times_seen\": 4.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03301052848554609, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08945419033820262, \"functional effect\": 0.0198, \"times_seen\": 6.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.025234571730254427, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08897333979111643, \"functional effect\": -0.1366, \"times_seen\": 9.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05651102620249261, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08407212330469575, \"functional effect\": 0.0105, \"times_seen\": 51.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0128704981025866, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.0866541015939871, \"functional effect\": -0.2935, \"times_seen\": 9.0}, {\"site\": 146, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.026249424151592666, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08585422375352608, \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.501330633138229, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.12375965450268808, \"functional effect\": -2.6709, \"times_seen\": 6.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.015111923809773175, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08651957702504275, \"functional effect\": 0.1988, \"times_seen\": 6.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.027859696898074732, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08575845050422982, \"functional effect\": -0.1035, \"times_seen\": 58.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0038004125677814147, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08766123162872404, \"functional effect\": 0.2968, \"times_seen\": 8.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.10621662491368561, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.09411046517913967, \"functional effect\": 0.056, \"times_seen\": 16.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.031110183279505415, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08556544860517679, \"functional effect\": -0.1747, \"times_seen\": 15.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.030539396058013653, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08559930837873002, \"functional effect\": -0.0578, \"times_seen\": 68.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.7679942045375392, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.14888564339271296, \"functional effect\": 0.0097, \"times_seen\": 66.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.2143895885381504, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.10143812823103596, \"functional effect\": -0.0447, \"times_seen\": 47.0}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 147, \"wildtype\": \"W\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.005058333713997719, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08773769893593357, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.023118307299653935, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08604075765241775, \"functional effect\": -0.0214, \"times_seen\": 13.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.20732452191990924, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.07572732744045468, \"functional effect\": 0.0462, \"times_seen\": 82.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.016850286238816292, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08845776691376579, \"functional effect\": -0.2152, \"times_seen\": 13.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03715135559554813, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08971131080856733, \"functional effect\": 0.0377, \"times_seen\": 60.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.012896267743500571, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08665255377890829, \"functional effect\": 0.0217, \"times_seen\": 15.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08280665679610098, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08255364290002132, \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.5282061748537064, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.06062582023688733, \"functional effect\": 0.0424, \"times_seen\": 41.0}, {\"site\": 148, \"wildtype\": \"M\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.04330009753783682, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.09009447484214358, \"functional effect\": 0.1417, \"times_seen\": 11.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.10696611822820447, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08118270537059652, \"functional effect\": -0.0626, \"times_seen\": 31.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.8521406558439424, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.04843325219565719, \"functional effect\": 0.0613, \"times_seen\": 38.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0002314668837845828, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08741658803320333, \"functional effect\": 0.0981, \"times_seen\": 17.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.016572957628355624, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08643200200842893, \"functional effect\": -0.1528, \"times_seen\": 52.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.060572542819219664, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.09117959992037389, \"functional effect\": -0.1484, \"times_seen\": 73.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03096242775757093, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.0893272881155236, \"functional effect\": -0.0372, \"times_seen\": 72.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0014695444927796827, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08751971745518919, \"functional effect\": -0.1094, \"times_seen\": 14.0}, {\"site\": 149, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.06895256080925347, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.0917107656209655, \"functional effect\": 0.0753, \"times_seen\": 14.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0095017578624355, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08685667818286628, \"functional effect\": -0.0872, \"times_seen\": 18.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.008035799834707218, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08694498025200478, \"functional effect\": -0.0684, \"times_seen\": 19.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.051857683818265, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08434373162602478, \"functional effect\": -0.1026, \"times_seen\": 54.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.001061342850905194, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08749495779521672, \"functional effect\": 0.0315, \"times_seen\": 19.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.14357109260389284, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.07914879814214756, \"functional effect\": 0.1457, \"times_seen\": 39.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.008056221406494262, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08694374954105143, \"functional effect\": -0.4192, \"times_seen\": 7.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.018153749540047125, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08853772390555331, \"functional effect\": -0.025, \"times_seen\": 24.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.028945918179298567, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08569390630583477, \"functional effect\": 0.2218, \"times_seen\": 8.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.2814033555974368, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.0719370590738517, \"functional effect\": -0.1881, \"times_seen\": 11.0}, {\"site\": 150, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018287253319292533, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08632935937982526, \"functional effect\": -0.183, \"times_seen\": 10.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.009437307444470916, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08686055847225209, \"functional effect\": -2.2596, \"times_seen\": 1.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.04479885687980092, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.09018811909470481, \"functional effect\": -0.348, \"times_seen\": 25.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.015042650192603113, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08834700246826355, \"functional effect\": -0.2672, \"times_seen\": 13.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.3896042568919307, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.11453707754162627, \"functional effect\": -0.0483, \"times_seen\": 64.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.023308659789359334, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.0888546449253881, \"functional effect\": -0.1704, \"times_seen\": 25.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0312803775506445, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08555535507203244, \"functional effect\": -0.011, \"times_seen\": 27.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.029358045018298765, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.0892280048323734, \"functional effect\": -0.0518, \"times_seen\": 39.0}, {\"site\": 151, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.11426310616778457, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.09463682298029569, \"functional effect\": -0.0439, \"times_seen\": 27.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.007072606590974822, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08700304711774949, \"functional effect\": -2.1956, \"times_seen\": 3.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.08980741711450929, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08215401700740936, \"functional effect\": 0.0351, \"times_seen\": 24.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.19779016802684166, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.10027768593745483, \"functional effect\": 0.0147, \"times_seen\": 109.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04047356915762742, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08501190957751766, \"functional effect\": -0.0333, \"times_seen\": 96.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02273167057457496, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.0860638193348015, \"functional effect\": 0.0643, \"times_seen\": 47.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02313808089066866, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08603957838511248, \"functional effect\": -0.1051, \"times_seen\": 6.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.19827740906555763, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.07620370416790008, \"functional effect\": -0.0596, \"times_seen\": 71.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.10071714532541996, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.09375240379645224, \"functional effect\": -0.1837, \"times_seen\": 76.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.34669624646053315, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.1111807244423957, \"functional effect\": 0.0831, \"times_seen\": 84.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0948862073285771, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.09337424957912097, \"functional effect\": -0.1089, \"times_seen\": 26.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.10056704982821689, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.09374265046585582, \"functional effect\": -0.0042, \"times_seen\": 226.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0657871160015711, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08353329924617868, \"functional effect\": 0.1247, \"times_seen\": 27.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.9388214979914484, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.16760113734329016, \"functional effect\": 0.06, \"times_seen\": 53.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.20915848485815697, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.07563112354972987, \"functional effect\": -0.0087, \"times_seen\": 136.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.007164347805767776, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08786587000278952, \"functional effect\": -0.0048, \"times_seen\": 49.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0019706200320993373, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.0875501200038413, \"functional effect\": -0.0804, \"times_seen\": 106.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05417190659294416, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08420854455544965, \"functional effect\": 0.0097, \"times_seen\": 255.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.6534580740489179, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.055584416214611666, \"functional effect\": 0.0486, \"times_seen\": 93.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.1255005422956547, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08014641525875794, \"functional effect\": 0.01, \"times_seen\": 83.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.03702515951624279, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08521535279894892, \"functional effect\": 0.1925, \"times_seen\": 31.0}, {\"site\": 152, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.3266371037405752, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.06971656229788262, \"functional effect\": 0.0065, \"times_seen\": 94.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.011963469307769365, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08670859854286932, \"functional effect\": -0.1961, \"times_seen\": 29.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.6069917295173338, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.05740382241836627, \"functional effect\": 0.075, \"times_seen\": 54.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07919371023785247, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08276064138041449, \"functional effect\": 0.1199, \"times_seen\": 64.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0036425965109561343, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08721014310828758, \"functional effect\": 0.0516, \"times_seen\": 28.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.014586674789193687, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08831908409773583, \"functional effect\": 0.0289, \"times_seen\": 19.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 1.047183548479399, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.18067463624542787, \"functional effect\": 0.1885, \"times_seen\": 23.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.4598919206638256, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.12025545693479477, \"functional effect\": 0.086, \"times_seen\": 65.0}, {\"site\": 153, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.2091486752786345, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.1010702999965809, \"functional effect\": 0.044, \"times_seen\": 18.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.013349773514870825, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08824339577248966, \"functional effect\": 0.128, \"times_seen\": 20.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.051173574524315035, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08438373593160096, \"functional effect\": -0.1293, \"times_seen\": 32.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.13768720782927446, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.07947225760333533, \"functional effect\": -0.0272, \"times_seen\": 44.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.0349703064258053, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.17915157756821667, \"functional effect\": -0.0127, \"times_seen\": 41.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.017802292492352722, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08851615772820798, \"functional effect\": 0.1168, \"times_seen\": 16.0}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 154, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.021161364309959376, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08872249277132213, \"functional effect\": -0.0122, \"times_seen\": 1.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.00440910738959519, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08716382024277282, \"functional effect\": -2.7036, \"times_seen\": 1.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.05310053922886317, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08427110233161701, \"functional effect\": 0.2207, \"times_seen\": 21.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0448387791167323, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08475507499176359, \"functional effect\": -0.3634, \"times_seen\": 24.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.08502979974172926, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.0824265285683727, \"functional effect\": 0.0013, \"times_seen\": 18.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01300695437843327, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08664590586552952, \"functional effect\": -0.025, \"times_seen\": 66.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004699374618088907, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08714628482832529, \"functional effect\": 0.1281, \"times_seen\": 22.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.012368003900620851, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08818336561300506, \"functional effect\": -0.5272, \"times_seen\": 3.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03250620606276255, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.0894229253317807, \"functional effect\": -0.4175, \"times_seen\": 8.0}, {\"site\": 155, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.025571457976871267, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08899411853751973, \"functional effect\": -0.0075, \"times_seen\": 19.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0476173781526202, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.0845919956685258, \"functional effect\": 0.1208, \"times_seen\": 13.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.09649928189179012, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08177383235187247, \"functional effect\": -0.0904, \"times_seen\": 94.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.061945314420612685, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08375603934282574, \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.016276794655489455, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.0864497469826281, \"functional effect\": 0.0846, \"times_seen\": 10.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.020476770188018318, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08619844035514172, \"functional effect\": -0.1456, \"times_seen\": 32.0}, {\"site\": 156, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.19170100545099333, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.07655186525214859, \"functional effect\": 0.066, \"times_seen\": 26.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.3186167848992042, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.10903771437595641, \"functional effect\": 0.1466, \"times_seen\": 26.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.015565309443963215, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08649239139739556, \"functional effect\": -0.1564, \"times_seen\": 9.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.06766123868717504, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.09162871421590503, \"functional effect\": -0.1405, \"times_seen\": 15.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.043215012700057356, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08485052130386254, \"functional effect\": -0.0007, \"times_seen\": 89.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.2998288151805239, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.10762694101780927, \"functional effect\": -0.2646, \"times_seen\": 18.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.3535236058588055, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.06842933514242155, \"functional effect\": -0.0073, \"times_seen\": 65.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.04069250634290909, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08499900951514587, \"functional effect\": -0.2622, \"times_seen\": 12.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.06552073679587277, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.09149286706593283, \"functional effect\": -0.008, \"times_seen\": 11.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.013325032204181481, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08824188246684393, \"functional effect\": -0.0481, \"times_seen\": 19.0}, {\"site\": 157, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008875758633537425, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08689437430716482, \"functional effect\": 0.0921, \"times_seen\": 5.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.005617139047600288, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08777168934217372, \"functional effect\": 0.0687, \"times_seen\": 20.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.003666732037499309, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08720868414082901, \"functional effect\": 0.033, \"times_seen\": 3.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.009983008018522215, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08682770960822292, \"functional effect\": 0.2321, \"times_seen\": 17.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.03276480345883958, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08943895547508865, \"functional effect\": 0.047, \"times_seen\": 27.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.3189283191109181, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.1090612624199373, \"functional effect\": -0.0315, \"times_seen\": 18.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08282327418214068, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08255269202834459, \"functional effect\": 0.099, \"times_seen\": 12.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.003177352570474635, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0872382713906926, \"functional effect\": 0.2722, \"times_seen\": 1.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.008016754720877952, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0879178003163824, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.14036971461324427, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0963649331680141, \"functional effect\": 0.0681, \"times_seen\": 116.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.057998121565018476, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0839855084292102, \"functional effect\": 0.0047, \"times_seen\": 96.0}, {\"site\": 158, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05055234937285229, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08442007943150012, \"functional effect\": 0.0087, \"times_seen\": 82.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.021583624818225455, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08874846464133646, \"functional effect\": -0.1313, \"times_seen\": 35.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.005673242295174022, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.0870874780054596, \"functional effect\": -0.0898, \"times_seen\": 17.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.2065330050442485, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.10088722106556032, \"functional effect\": 0.014, \"times_seen\": 51.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011207294289999453, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.0867540579506568, \"functional effect\": -0.2323, \"times_seen\": 16.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.11589163010877347, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.09474370998357765, \"functional effect\": -0.1011, \"times_seen\": 19.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.09356807014937614, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08194014614567074, \"functional effect\": -0.1513, \"times_seen\": 28.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.062324800294546026, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08373401108806815, \"functional effect\": -0.1756, \"times_seen\": 70.0}, {\"site\": 159, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04354877296979597, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08483089383131032, \"functional effect\": -0.1064, \"times_seen\": 22.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.033873906084762526, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08540169063008052, \"functional effect\": -0.6996, \"times_seen\": 14.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0023108379535341397, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.0872906843686305, \"functional effect\": 0.1748, \"times_seen\": 1.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04226295102057911, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08490653424386792, \"functional effect\": -0.3027, \"times_seen\": 16.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0017538917745580584, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08753696881161767, \"functional effect\": -0.591, \"times_seen\": 5.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.06968882258930899, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08330769224664128, \"functional effect\": -0.311, \"times_seen\": 12.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04825841792025805, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08455441684136031, \"functional effect\": 0.0485, \"times_seen\": 23.0}, {\"site\": 160, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06485816921379656, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08358710339447088, \"functional effect\": -0.5794, \"times_seen\": 10.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.026068593689754102, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08902479014644998, \"functional effect\": -2.8512, \"times_seen\": 3.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.00494882239624242, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08713121818756996, \"functional effect\": -2.1822, \"times_seen\": 1.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.003921966346938401, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08719325698622228, \"functional effect\": -2.5685, \"times_seen\": 1.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.003148480245161532, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.0876216277774371, \"functional effect\": -2.8823, \"times_seen\": 2.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.017558470599110053, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08637297999070444, \"functional effect\": -2.9128, \"times_seen\": 6.0}, {\"site\": 161, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010747383856729069, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08678171830544695, \"functional effect\": -2.5698, \"times_seen\": 5.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0331419968852616, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08544502767588949, \"functional effect\": -1.1296, \"times_seen\": 11.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.10505363221469394, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08129039531140721, \"functional effect\": -0.2336, \"times_seen\": 8.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.020324643697339592, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.0862075301192612, \"functional effect\": -0.4323, \"times_seen\": 7.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01944479421371232, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.0862601211259835, \"functional effect\": -0.6835, \"times_seen\": 45.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03506336896784784, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08958156714976791, \"functional effect\": -0.708, \"times_seen\": 11.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.1357217255563123, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.03979030094452939, \"functional effect\": 0.0177, \"times_seen\": 71.0}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 162, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.2875198668357352, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.07163271726556382, \"functional effect\": -0.0554, \"times_seen\": 11.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.08126302976541853, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.09249667886083293, \"functional effect\": -0.4392, \"times_seen\": 23.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.6794208339135668, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.14001984116038863, \"functional effect\": -0.4464, \"times_seen\": 19.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0077365922406222466, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.08790072887936226, \"functional effect\": -0.3046, \"times_seen\": 5.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.32642119711678746, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.06972699651546944, \"functional effect\": -0.0966, \"times_seen\": 62.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.10371079452234402, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.09394714571630204, \"functional effect\": -0.5267, \"times_seen\": 9.0}, {\"site\": 163, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.020935978563455863, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.08870863313863767, \"functional effect\": 0.0364, \"times_seen\": 2.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.028201052533369315, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08915647568502225, \"functional effect\": -1.1936, \"times_seen\": 6.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.06251740919195065, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08372283281507732, \"functional effect\": 0.0394, \"times_seen\": 29.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.017060978291880753, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08847068628269918, \"functional effect\": -0.515, \"times_seen\": 3.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.1910275167560559, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.07658761005634239, \"functional effect\": -0.4174, \"times_seen\": 92.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.05033936245542024, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08443254339600813, \"functional effect\": 0.0342, \"times_seen\": 19.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05899848471567761, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.0839272931558022, \"functional effect\": -0.3936, \"times_seen\": 11.0}, {\"site\": 164, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01388768156352385, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08827630340824914, \"functional effect\": -0.3211, \"times_seen\": 15.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.004376261510655689, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08769622842423314, \"functional effect\": -1.4378, \"times_seen\": 1.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0035015849986368562, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08721866759533185, \"functional effect\": -0.3881, \"times_seen\": 16.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.02523913451536991, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08591436675492596, \"functional effect\": -0.7147, \"times_seen\": 14.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.017506378338463042, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08637609876833284, \"functional effect\": -0.0061, \"times_seen\": 20.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.182510387537664, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.09922123563133017, \"functional effect\": -0.059, \"times_seen\": 60.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.007328351523501438, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08698762555204623, \"functional effect\": -0.2233, \"times_seen\": 7.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.016128067251721962, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.0884134956790877, \"functional effect\": -0.1524, \"times_seen\": 7.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.03404933768276645, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08951862481434998, \"functional effect\": -0.7647, \"times_seen\": 4.0}, {\"site\": 165, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.06481621393630226, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08358953424160881, \"functional effect\": -0.2477, \"times_seen\": 18.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.038080905727887804, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08976913178204483, \"functional effect\": -0.1624, \"times_seen\": 47.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.012123857608503005, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08669895944980256, \"functional effect\": -0.6295, \"times_seen\": 13.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.017812944587450218, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08635774618333744, \"functional effect\": 0.0418, \"times_seen\": 4.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.010299470719394065, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08680866558488969, \"functional effect\": 0.0087, \"times_seen\": 34.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.050592294064070883, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.09055101609985677, \"functional effect\": 0.0754, \"times_seen\": 48.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.04238880556257229, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.0900375837842957, \"functional effect\": -0.14, \"times_seen\": 37.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.008315815634568353, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08692810655037604, \"functional effect\": -0.0036, \"times_seen\": 14.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.012395291637035556, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08668264911843852, \"functional effect\": -0.1799, \"times_seen\": 5.0}, {\"site\": 166, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.03693131330560342, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08522089617286462, \"functional effect\": -0.0799, \"times_seen\": 6.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004878736664697601, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08713545110119772, \"functional effect\": -1.1398, \"times_seen\": 1.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.01823588954865377, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.0863324329887478, \"functional effect\": -0.1085, \"times_seen\": 28.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.005241413938651379, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.0871135489839047, \"functional effect\": -0.1978, \"times_seen\": 7.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0070166465017684745, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08700642190768507, \"functional effect\": -0.5557, \"times_seen\": 3.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.15754280292689898, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.07838598511078701, \"functional effect\": -0.1065, \"times_seen\": 6.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.06448638736713083, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08360864652817383, \"functional effect\": -0.0688, \"times_seen\": 32.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.014209725575029641, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08657369949687801, \"functional effect\": -0.2875, \"times_seen\": 3.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.028823933066158696, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08570115234363762, \"functional effect\": -0.0488, \"times_seen\": 23.0}, {\"site\": 167, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.012920074859227016, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08821711688389815, \"functional effect\": -0.3347, \"times_seen\": 14.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.015094497231695524, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08652062211719855, \"functional effect\": -0.1765, \"times_seen\": 3.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.005294504056225248, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08775206284369984, \"functional effect\": 0.0195, \"times_seen\": 29.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0003063811709422165, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08741204890250119, \"functional effect\": -0.1131, \"times_seen\": 29.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03303819130090309, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08945590558529526, \"functional effect\": 0.0819, \"times_seen\": 10.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.025110064660314405, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08896566156978558, \"functional effect\": -0.1616, \"times_seen\": 13.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.7672370056829882, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.05136912609643919, \"functional effect\": 0.0184, \"times_seen\": 19.0}, {\"site\": 168, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008845204714804765, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08689621460722113, \"functional effect\": 0.1903, \"times_seen\": 11.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.3356149796577892, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.11033002226814921, \"functional effect\": -0.0202, \"times_seen\": 16.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.1065232900980242, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08120762782648855, \"functional effect\": -0.2334, \"times_seen\": 21.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.029493546682144586, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08566138417281524, \"functional effect\": -0.2764, \"times_seen\": 33.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0009397971236508535, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08748758673618606, \"functional effect\": -0.4791, \"times_seen\": 5.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.01750545794965561, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08849794739987382, \"functional effect\": -0.2852, \"times_seen\": 6.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04188202921667955, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08492895548983678, \"functional effect\": 0.1185, \"times_seen\": 39.0}, {\"site\": 169, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.1424709954334642, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.09650539065525428, \"functional effect\": 0.0123, \"times_seen\": 35.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.007600667386328203, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08697120775469301, \"functional effect\": 0.2269, \"times_seen\": 1.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03480899704314378, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08534635497580417, \"functional effect\": 0.0932, \"times_seen\": 22.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03935457759359253, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.0850778725899485, \"functional effect\": -0.0807, \"times_seen\": 30.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.009768989406075143, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08802464632713711, \"functional effect\": -0.1024, \"times_seen\": 26.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.02271939213504381, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08606455180692373, \"functional effect\": 0.1541, \"times_seen\": 5.0}, {\"site\": 170, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01623744553072667, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08645210490871384, \"functional effect\": -0.6476, \"times_seen\": 3.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.023796582847375056, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08600031554660263, \"functional effect\": -2.6513, \"times_seen\": 6.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.353524358921596, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.11170817743984834, \"functional effect\": -0.075, \"times_seen\": 88.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -1.2754778205796005, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.036116565727412675, \"functional effect\": -0.175, \"times_seen\": 42.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.042502844901305604, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08489241700907088, \"functional effect\": -0.2332, \"times_seen\": 24.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.017431109562118335, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08638060532909284, \"functional effect\": -0.0566, \"times_seen\": 40.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.8336132522004561, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.15581387331519483, \"functional effect\": 0.0043, \"times_seen\": 75.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.1299871938226176, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.07989755430016242, \"functional effect\": -0.0638, \"times_seen\": 64.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.11473139893468424, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.09466754668272925, \"functional effect\": -0.0169, \"times_seen\": 66.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.164387855420657, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.07801495360485747, \"functional effect\": 0.0243, \"times_seen\": 48.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.5747165299103926, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.13021782719596087, \"functional effect\": -0.3255, \"times_seen\": 60.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.3439882713127989, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.03444155462828461, \"functional effect\": 0.0666, \"times_seen\": 68.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.00116327809005681, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08750114006817578, \"functional effect\": -0.0796, \"times_seen\": 29.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.06764478374122049, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08342580788607949, \"functional effect\": -0.1479, \"times_seen\": 181.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.018459456500533804, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08855648702984772, \"functional effect\": -0.1346, \"times_seen\": 95.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.047128098876570323, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.09033384609847683, \"functional effect\": -0.2682, \"times_seen\": 142.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.21775525092074874, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.10167504942783796, \"functional effect\": -0.0793, \"times_seen\": 132.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.7579970551833624, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.05169918296620218, \"functional effect\": -0.0044, \"times_seen\": 94.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.02006209279776917, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08865491580003278, \"functional effect\": -0.0387, \"times_seen\": 106.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.11485070821679245, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08074023735094857, \"functional effect\": 0.0425, \"times_seen\": 31.0}, {\"site\": 171, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.028397880903894564, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08572646507587574, \"functional effect\": -0.0488, \"times_seen\": 34.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.4435203468112723, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.11889852254795884, \"functional effect\": 0.0731, \"times_seen\": 130.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.23840198290353348, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.10314060578091423, \"functional effect\": 0.0748, \"times_seen\": 121.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04628406198335487, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08467021040335951, \"functional effect\": -0.0551, \"times_seen\": 39.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.019159933496577616, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08859949462462888, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.043968206301342114, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.0848062346124805, \"functional effect\": 0.0645, \"times_seen\": 12.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.09375460583785618, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.09330103867257138, \"functional effect\": -0.0037, \"times_seen\": 38.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.12151949121526773, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08036788105338313, \"functional effect\": -0.0063, \"times_seen\": 46.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.005618126073784334, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08777174939158318, \"functional effect\": 0.1881, \"times_seen\": 13.0}, {\"site\": 172, \"wildtype\": \"M\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04197506373561388, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.09001176614981214, \"functional effect\": 0.1976, \"times_seen\": 19.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.009670602901369646, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08684651355302182, \"functional effect\": -0.0751, \"times_seen\": 100.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.02465485881101331, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08594916817993568, \"functional effect\": -0.359, \"times_seen\": 40.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0283173079802686, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08916366039367937, \"functional effect\": -0.0638, \"times_seen\": 47.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.10387617973192012, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08135676737530965, \"functional effect\": -0.2507, \"times_seen\": 48.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.21113523446772745, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.07552756637857351, \"functional effect\": -0.0331, \"times_seen\": 128.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.4304657280208284, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.11782748997448816, \"functional effect\": -0.0807, \"times_seen\": 106.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.4502404832557167, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.11945364895123535, \"functional effect\": -0.2644, \"times_seen\": 32.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.009882940758030128, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.0868337323033337, \"functional effect\": 0.1292, \"times_seen\": 27.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.9386927504135071, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.16758618111409537, \"functional effect\": -0.2273, \"times_seen\": 61.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.02327666317739511, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08603131399899779, \"functional effect\": -0.4233, \"times_seen\": 20.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.38565167929899585, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.06692229200896439, \"functional effect\": -0.0223, \"times_seen\": 168.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.06805549440448305, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08340206136223871, \"functional effect\": -0.1434, \"times_seen\": 44.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.08015645004367002, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.09242575901844721, \"functional effect\": -0.0238, \"times_seen\": 20.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0034167131160954683, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08722379870762045, \"functional effect\": -0.1216, \"times_seen\": 68.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.979244489695451, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.04434876858763755, \"functional effect\": -0.0435, \"times_seen\": 115.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.14055666728543523, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.0793143477322006, \"functional effect\": -0.0833, \"times_seen\": 105.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.10472819776022226, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08130873437730253, \"functional effect\": -0.2056, \"times_seen\": 80.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.035074982064252046, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08533062139464276, \"functional effect\": -0.3205, \"times_seen\": 13.0}, {\"site\": 173, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.16889099043899125, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.07777182241737521, \"functional effect\": -0.2031, \"times_seen\": 137.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.10408268727223585, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.08134512279134236, \"functional effect\": 0.1159, \"times_seen\": 80.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.09505729089515508, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.09338532312302576, \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.00356053672690211, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.0876466574720166, \"functional effect\": -0.1622, \"times_seen\": 3.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0044582823134672045, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.08770121431475501, \"functional effect\": 0.2061, \"times_seen\": 27.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.2362854290817852, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.0742223205314818, \"functional effect\": -0.1583, \"times_seen\": 13.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06992374597198232, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.0832941278196717, \"functional effect\": 0.0705, \"times_seen\": 32.0}, {\"site\": 174, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.025092821481427996, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.08896459825314124, \"functional effect\": -0.2258, \"times_seen\": 1.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.5319578720790731, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.06046836891676822, \"functional effect\": -0.1565, \"times_seen\": 22.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.010607547018958018, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08679013024896967, \"functional effect\": -0.0057, \"times_seen\": 60.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.06984790396247939, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08329850668000179, \"functional effect\": -0.0243, \"times_seen\": 83.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.04310762709968321, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.09008245610921284, \"functional effect\": 0.0545, \"times_seen\": 62.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0044617017050962065, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.0871606426911967, \"functional effect\": -0.2727, \"times_seen\": 8.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.9944034582274643, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.02194260905992527, \"functional effect\": 0.0304, \"times_seen\": 13.0}, {\"site\": 175, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.034866776966459734, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08534293692350763, \"functional effect\": -0.137, \"times_seen\": 50.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.009552318524542717, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.08801142735496574, \"functional effect\": 0.0869, \"times_seen\": 1.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.11197555003726428, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.08090130564240965, \"functional effect\": 0.0627, \"times_seen\": 47.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.05022439440594681, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.09052792775502694, \"functional effect\": 0.0515, \"times_seen\": 4.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.17945617880945766, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.07720436179154112, \"functional effect\": 0.0625, \"times_seen\": 42.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.429773702568826, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.11777098456860206, \"functional effect\": 0.0764, \"times_seen\": 47.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.003199502029940792, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.0872369320461545, \"functional effect\": -0.2688, \"times_seen\": 14.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.1756197278797425, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.07740993878835833, \"functional effect\": -0.0258, \"times_seen\": 36.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02379221366055348, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.08888443168396022, \"functional effect\": 0.0761, \"times_seen\": 22.0}, {\"site\": 176, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.12945577715533213, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.09563868630307326, \"functional effect\": 0.016, \"times_seen\": 37.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.006949346759142263, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.08785277655899797, \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02865834950475951, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.0857109891532268, \"functional effect\": 0.0575, \"times_seen\": 104.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.13015768992973428, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.09568522860531582, \"functional effect\": 0.0654, \"times_seen\": 15.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.09386678996002522, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.0819231816380355, \"functional effect\": 0.0764, \"times_seen\": 131.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.026991170242380413, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.0858100940759906, \"functional effect\": -0.0279, \"times_seen\": 17.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.528385358984348, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.06061829091849047, \"functional effect\": 0.0177, \"times_seen\": 116.0}, {\"site\": 177, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.022916757076369344, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.0860527787274349, \"functional effect\": 0.2054, \"times_seen\": 22.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.00638228058288168, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08704468782225773, \"functional effect\": -2.6882, \"times_seen\": 5.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.006161664287254868, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08780482380200512, \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -1.3839276350827132, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.033501156524159886, \"functional effect\": 0.1254, \"times_seen\": 23.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.08621204803428624, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.09281452414474925, \"functional effect\": -0.0332, \"times_seen\": 102.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.01393979546901352, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08827949223602842, \"functional effect\": 0.0011, \"times_seen\": 13.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.2653864188749737, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.07274016091124202, \"functional effect\": 0.0052, \"times_seen\": 74.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.006114326468249634, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08780194279073915, \"functional effect\": -0.4437, \"times_seen\": 8.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03449922914821099, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08536468206395645, \"functional effect\": 0.0312, \"times_seen\": 51.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.030242691531465197, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08928273535214476, \"functional effect\": 0.1608, \"times_seen\": 6.0}, {\"site\": 178, \"wildtype\": \"Q\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0214758161081907, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08874183295567997, \"functional effect\": 0.0808, \"times_seen\": 3.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0191040426524321, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08628049739512066, \"functional effect\": 0.1384, \"times_seen\": 15.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.04016361938875641, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.0898988185207259, \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.005396571342941596, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08775827131572031, \"functional effect\": 0.0672, \"times_seen\": 133.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03213576352357849, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08550464362055511, \"functional effect\": 0.0312, \"times_seen\": 76.0}, {\"site\": 179, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.018780218869339258, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08629986587712961, \"functional effect\": 0.0414, \"times_seen\": 49.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.038271678680043525, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08978100307440594, \"functional effect\": 0.0329, \"times_seen\": 49.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.19946338978052658, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.0761410859541352, \"functional effect\": 0.0399, \"times_seen\": 38.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.020923515036786886, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08617175228425873, \"functional effect\": -0.0217, \"times_seen\": 24.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06847018088798254, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.0833780918216203, \"functional effect\": -0.0815, \"times_seen\": 66.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03073446151301635, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08931317425428022, \"functional effect\": 0.027, \"times_seen\": 16.0}, {\"site\": 180, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04913231248846889, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08450321456468513, \"functional effect\": 0.0688, \"times_seen\": 28.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004561055930148983, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08715464039709836, \"functional effect\": -0.1598, \"times_seen\": 1.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.006956566066287209, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08785321617911616, \"functional effect\": -0.0153, \"times_seen\": 24.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0706723595746257, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.0918201567977076, \"functional effect\": -0.0256, \"times_seen\": 44.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04601722697515981, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.09026431601480021, \"functional effect\": -0.0144, \"times_seen\": 46.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.022926108082917646, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08605222096750174, \"functional effect\": -0.0381, \"times_seen\": 13.0}, {\"site\": 181, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007421092423265867, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08698203389813244, \"functional effect\": 0.0674, \"times_seen\": 2.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.5487767439929001, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.1278974220699592, \"functional effect\": 0.0127, \"times_seen\": 50.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05084061253791893, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.09056660319533594, \"functional effect\": 0.1137, \"times_seen\": 18.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0021293857282412847, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.0875597552491391, \"functional effect\": 0.3116, \"times_seen\": 2.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0043965985027245545, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.08716457599992354, \"functional effect\": 0.1255, \"times_seen\": 27.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.007753876762518781, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.0879017819994821, \"functional effect\": 0.1238, \"times_seen\": 22.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.8994652337765403, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.16309083091892196, \"functional effect\": -0.0472, \"times_seen\": 36.0}, {\"site\": 182, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.010502996572661509, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.08806944246100895, \"functional effect\": -0.0964, \"times_seen\": 3.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02093975968861271, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.08617078200142526, \"functional effect\": -0.1389, \"times_seen\": 15.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.037071840426687805, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.0897063664417763, \"functional effect\": 0.0499, \"times_seen\": 9.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.05895333378119194, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.09107732188666257, \"functional effect\": 0.012, \"times_seen\": 18.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06455838209368026, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.08360447431486233, \"functional effect\": 0.1074, \"times_seen\": 73.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03360350205945404, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.0894909651741508, \"functional effect\": 0.2032, \"times_seen\": 18.0}, {\"site\": 183, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12131661697827248, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.0803791833165279, \"functional effect\": 0.0384, \"times_seen\": 62.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.032012987805378645, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08551192051583725, \"functional effect\": 0.1499, \"times_seen\": 25.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01982720483025372, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08623725945826953, \"functional effect\": 0.1391, \"times_seen\": 11.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.014081103526909384, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08658141823342282, \"functional effect\": 0.143, \"times_seen\": 3.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.017020929327370288, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08640516814612591, \"functional effect\": -2.8453, \"times_seen\": 5.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0009980441833055578, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08737015148915722, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 184, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00552255833581482, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08709657443329465, \"functional effect\": -0.9961, \"times_seen\": 1.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03733915722762444, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08519680798291042, \"functional effect\": -0.0488, \"times_seen\": 25.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04038548106446084, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08991264447537393, \"functional effect\": -0.184, \"times_seen\": 4.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.015681585886347625, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08648542067800628, \"functional effect\": -0.0704, \"times_seen\": 28.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.1395638349114573, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.09631111939887169, \"functional effect\": -0.2213, \"times_seen\": 35.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.01324670296449317, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08823709161934463, \"functional effect\": 0.0191, \"times_seen\": 8.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.14781074218020565, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.09686324117623837, \"functional effect\": -0.0367, \"times_seen\": 42.0}, {\"site\": 185, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.009614264476686157, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08684990504682977, \"functional effect\": 0.0793, \"times_seen\": 17.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.00025067853582210094, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08744580734144837, \"functional effect\": -1.3138, \"times_seen\": 1.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0028687224700515617, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08725693592880586, \"functional effect\": -2.6406, \"times_seen\": 1.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.029649899261337858, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08924605730037667, \"functional effect\": -2.9466, \"times_seen\": 4.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0047585479767110455, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08714271052296897, \"functional effect\": -1.0278, \"times_seen\": 1.0}, {\"site\": 186, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009181135390071326, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08687598323127396, \"functional effect\": -1.948, \"times_seen\": 4.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.021214115643584993, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.0887257369187335, \"functional effect\": -0.3386, \"times_seen\": 4.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.09684997563947254, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.0817539569896557, \"functional effect\": -0.2058, \"times_seen\": 24.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.010773129041916948, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.08678016968192603, \"functional effect\": -0.8613, \"times_seen\": 2.0}, {\"site\": 187, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.017347940052596312, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.08848828544832174, \"functional effect\": -0.2117, \"times_seen\": 12.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.007084629751750708, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08700232205303723, \"functional effect\": 0.1895, \"times_seen\": 1.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.011683681539008985, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08672541592783584, \"functional effect\": -0.3795, \"times_seen\": 12.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.09821856966720213, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08167643892773369, \"functional effect\": 0.1124, \"times_seen\": 43.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.050505833640312345, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08442280136859052, \"functional effect\": -0.4666, \"times_seen\": 15.0}, {\"site\": 188, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.007061071277373893, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08700374276819298, \"functional effect\": -0.6875, \"times_seen\": 3.0}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.023596228657883515, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08601225966474842, \"functional effect\": -0.1861, \"times_seen\": 7.0}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.000744426438920803, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08747573991343102, \"functional effect\": -1.0215, \"times_seen\": 1.0}, {\"site\": 189, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.052977920912686646, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08427826505104935, \"functional effect\": -0.537, \"times_seen\": 6.0}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.012120300834492486, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.08669917319489566, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02225089736761308, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.08609250458873241, \"functional effect\": -1.997, \"times_seen\": 3.0}, {\"site\": 190, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3721680846136195, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.06755068744298778, \"functional effect\": -0.7651, \"times_seen\": 42.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.007168929823774706, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.0869972384507988, \"functional effect\": -0.2374, \"times_seen\": 1.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.016829541341339002, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08845649496504453, \"functional effect\": 0.2717, \"times_seen\": 7.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.036022702709374396, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08527458527261869, \"functional effect\": 0.3306, \"times_seen\": 16.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01833784111511795, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08632633231220842, \"functional effect\": -0.752, \"times_seen\": 4.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0009019697293332471, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08737596998777357, \"functional effect\": 0.249, \"times_seen\": 9.0}, {\"site\": 191, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03700956106463281, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08521627415426326, \"functional effect\": 0.3514, \"times_seen\": 10.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.019515341076294945, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08862132377772092, \"functional effect\": 0.4293, \"times_seen\": 14.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.023934656559283972, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.0859920852454973, \"functional effect\": 0.0857, \"times_seen\": 11.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.007940793425506302, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08791317135877415, \"functional effect\": 0.1366, \"times_seen\": 2.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.00010550071381034172, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08743700814774526, \"functional effect\": -0.33, \"times_seen\": 9.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.011276234846934565, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08811665750950144, \"functional effect\": -0.0423, \"times_seen\": 34.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03510205337569568, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08958396922105961, \"functional effect\": -0.1628, \"times_seen\": 19.0}, {\"site\": 192, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.00619418381922228, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08780680301720656, \"functional effect\": -0.0628, \"times_seen\": 7.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.014304222551938242, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.0883017945941473, \"functional effect\": -0.1032, \"times_seen\": 14.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.474444762083886, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.12147464390613782, \"functional effect\": -0.3554, \"times_seen\": 10.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.09739341015911962, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.09353666209027957, \"functional effect\": -0.0112, \"times_seen\": 29.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.009761612871832212, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08802419625616613, \"functional effect\": 0.041, \"times_seen\": 24.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.004719754234580017, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08714505380217691, \"functional effect\": 0.0024, \"times_seen\": 16.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.11485316163129962, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08074010004604658, \"functional effect\": 0.3645, \"times_seen\": 14.0}, {\"site\": 193, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01372420266116338, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08826630095092738, \"functional effect\": -0.081, \"times_seen\": 14.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05662051119350371, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08406574337952377, \"functional effect\": -0.2591, \"times_seen\": 11.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04591303053737445, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08469198863766311, \"functional effect\": -1.1385, \"times_seen\": 43.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0256951973242992, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08900175185301928, \"functional effect\": -0.8634, \"times_seen\": 41.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.07069640592027983, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08324953017171077, \"functional effect\": -0.7793, \"times_seen\": 9.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06508683973912718, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08357385569375587, \"functional effect\": -0.2356, \"times_seen\": 23.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.07476584318732983, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08301503751728487, \"functional effect\": -0.9871, \"times_seen\": 33.0}, {\"site\": 194, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.005021899976503055, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08712680479655625, \"functional effect\": -0.2722, \"times_seen\": 4.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.007683555151072786, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08696621110486677, \"functional effect\": 0.2463, \"times_seen\": 39.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.003857875511597021, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08766472326944119, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.008037108285378361, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08791904067085202, \"functional effect\": 0.4444, \"times_seen\": 13.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.6407351148904864, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.13631511642239055, \"functional effect\": 0.1067, \"times_seen\": 58.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.08303860293751815, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.0825403715854111, \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03504496903221126, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08533239658429873, \"functional effect\": 0.338, \"times_seen\": 8.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.008285035387118153, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.0869299612023277, \"functional effect\": 0.0289, \"times_seen\": 6.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0018076725331019048, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08732113384878573, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 195, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004400405017357414, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08716434601868225, \"functional effect\": 0.1425, \"times_seen\": 1.0}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.043759545655321475, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08481850124052709, \"functional effect\": 0.3392, \"times_seen\": 14.0}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.017240319142315896, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08639202956032627, \"functional effect\": -1.9717, \"times_seen\": 3.0}, {\"site\": 196, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.013867811079773801, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08827508757210704, \"functional effect\": 0.255, \"times_seen\": 1.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.003086409337976275, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.0876178580015846, \"functional effect\": -0.5772, \"times_seen\": 8.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.020298077075089623, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.0862091176092781, \"functional effect\": -0.2777, \"times_seen\": 4.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.039406285659966275, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.0850748233430028, \"functional effect\": -0.3112, \"times_seen\": 29.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.8829712253712942, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.023704604305343765, \"functional effect\": 0.0764, \"times_seen\": 49.0}, {\"site\": 197, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04211456335061552, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.08491526771170581, \"functional effect\": 0.0004, \"times_seen\": 6.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.051271008740781776, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.09059362577178803, \"functional effect\": -0.2275, \"times_seen\": 46.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.045619044492819186, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.09023940658562651, \"functional effect\": -0.3953, \"times_seen\": 67.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.07738078431939859, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.08286470580034873, \"functional effect\": -0.445, \"times_seen\": 20.0}, {\"site\": 198, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.17643764998497027, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.07736606440486365, \"functional effect\": -0.0588, \"times_seen\": 58.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.00041051161092744065, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.08745549581070274, \"functional effect\": -0.7565, \"times_seen\": 17.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.49905467178529755, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.061863303025602084, \"functional effect\": -0.0822, \"times_seen\": 41.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.16354044776499754, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.09792511951017752, \"functional effect\": -0.164, \"times_seen\": 65.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.3109767134340224, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.21692362051712116, \"functional effect\": 0.0432, \"times_seen\": 13.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0025914105859291795, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.08758780085881407, \"functional effect\": 0.1136, \"times_seen\": 1.0}, {\"site\": 199, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.03411288158656002, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.0853875454219329, \"functional effect\": 0.0281, \"times_seen\": 10.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.012101549929878568, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08670030004322139, \"functional effect\": -0.0198, \"times_seen\": 3.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.20472926215109222, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.07586367570343854, \"functional effect\": -0.1648, \"times_seen\": 49.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.10947125786013652, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08104185956699049, \"functional effect\": -0.2185, \"times_seen\": 26.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.46912832950912237, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.12102782509476477, \"functional effect\": 0.0784, \"times_seen\": 31.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.06082420727107669, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08382115080824241, \"functional effect\": -0.0072, \"times_seen\": 19.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.008416746045191504, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08692202530496708, \"functional effect\": 0.0049, \"times_seen\": 5.0}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 200, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03794920903022605, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08516078964395968, \"functional effect\": 0.0358, \"times_seen\": 16.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.08522933236560491, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.09275132351888869, \"functional effect\": -0.1606, \"times_seen\": 6.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.027369344020242093, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08910509210942595, \"functional effect\": -0.6104, \"times_seen\": 9.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00467970529894559, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08714747296561333, \"functional effect\": 0.1011, \"times_seen\": 1.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.025803073585709803, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.0858807900124347, \"functional effect\": -0.0949, \"times_seen\": 8.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.024714804816809804, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.0889412906973286, \"functional effect\": -0.6998, \"times_seen\": 10.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0043002870310343035, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.0871703951291069, \"functional effect\": -0.9007, \"times_seen\": 9.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.07751757303103685, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.09225685479595527, \"functional effect\": -0.2913, \"times_seen\": 27.0}, {\"site\": 201, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.018466859403755583, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08631861260891371, \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0025305956765468763, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08727738887612323, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0019566770249730982, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.0875492738748856, \"functional effect\": -0.0465, \"times_seen\": 10.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0032081155855569633, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08723641120293989, \"functional effect\": -0.0726, \"times_seen\": 19.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05886147647174274, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.0839352638472818, \"functional effect\": -0.0033, \"times_seen\": 12.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.10373270243099278, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.09394857235260085, \"functional effect\": 0.0603, \"times_seen\": 25.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.012346942509043373, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08818207826482374, \"functional effect\": -0.1124, \"times_seen\": 6.0}, {\"site\": 202, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.029672892944496602, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08565073598053109, \"functional effect\": -0.0474, \"times_seen\": 70.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.07636671369232845, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08292297189352599, \"functional effect\": -0.0387, \"times_seen\": 44.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.10143571529104473, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08149450703556887, \"functional effect\": -0.0312, \"times_seen\": 41.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012823799652278084, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08665690653726031, \"functional effect\": -0.1878, \"times_seen\": 17.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.007858519711683581, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08695566481348124, \"functional effect\": -0.0927, \"times_seen\": 6.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.08073625289911744, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.09246291135298089, \"functional effect\": -0.0399, \"times_seen\": 38.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.023169388968927354, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08884606774056258, \"functional effect\": -0.2993, \"times_seen\": 11.0}, {\"site\": 203, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.07475111818244962, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.09208011621416573, \"functional effect\": 0.2003, \"times_seen\": 63.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0038564113452588915, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08719721907371306, \"functional effect\": 0.045, \"times_seen\": 55.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0023887122437297953, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08757549565613676, \"functional effect\": 0.0731, \"times_seen\": 6.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.06092703547402624, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08381517666200673, \"functional effect\": 0.0513, \"times_seen\": 14.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.002850269493738152, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08725805200699543, \"functional effect\": -0.0455, \"times_seen\": 33.0}, {\"site\": 204, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.021978500390935737, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.0887727590321959, \"functional effect\": 0.1251, \"times_seen\": 29.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.08353322662066827, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08251207771620346, \"functional effect\": -0.0943, \"times_seen\": 21.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.005519990473879477, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08709672945717072, \"functional effect\": 0.0024, \"times_seen\": 33.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02433301535404403, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08596834427908544, \"functional effect\": 0.0427, \"times_seen\": 4.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.00261023367994457, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08727257122238564, \"functional effect\": 0.1542, \"times_seen\": 6.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 1.0278977941198766, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.17827547344279182, \"functional effect\": 0.0091, \"times_seen\": 66.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0005397915412997943, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08739790784860482, \"functional effect\": -0.0732, \"times_seen\": 28.0}, {\"site\": 205, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04727118067703486, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08461229729053853, \"functional effect\": -0.0985, \"times_seen\": 21.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0007552871174273339, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08738485418484913, \"functional effect\": -2.7994, \"times_seen\": 4.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"A\", \"log2 fold change IC90\": -2.706965417250039, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.013390159250328815, \"functional effect\": -0.0728, \"times_seen\": 122.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.16825600222107048, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.09824571860424501, \"functional effect\": -0.0454, \"times_seen\": 97.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.4165644041426136, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.06550359701859916, \"functional effect\": 0.0567, \"times_seen\": 102.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.08707385087451162, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08230982702425331, \"functional effect\": -0.065, \"times_seen\": 42.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02216641531042206, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08609754618425353, \"functional effect\": 0.0738, \"times_seen\": 149.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.12499815094355918, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0953436387992886, \"functional effect\": -0.0576, \"times_seen\": 81.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.7530375729271923, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.05187721254808963, \"functional effect\": -0.0446, \"times_seen\": 96.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.020460865625766208, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08867942413817205, \"functional effect\": 0.0143, \"times_seen\": 34.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.5067828899865715, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.06153280014623848, \"functional effect\": 0.0161, \"times_seen\": 133.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0826651987125484, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08256173778654836, \"functional effect\": 0.0034, \"times_seen\": 32.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.14115396869032978, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.09641733172391924, \"functional effect\": 0.0533, \"times_seen\": 96.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.846024820985477, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.15716012955654873, \"functional effect\": 0.0835, \"times_seen\": 89.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.3521061385975841, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0684966009229471, \"functional effect\": -0.1415, \"times_seen\": 24.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.42810101073557855, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.06498188190482723, \"functional effect\": 0.0084, \"times_seen\": 153.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.13418555872508056, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.079665383624251, \"functional effect\": -0.0246, \"times_seen\": 308.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.05666426740630926, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0909329277343721, \"functional effect\": 0.052, \"times_seen\": 149.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.10293697126983103, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08140974866361964, \"functional effect\": 0.0672, \"times_seen\": 149.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.027970826227428906, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08575184487256376, \"functional effect\": 0.0393, \"times_seen\": 25.0}, {\"site\": 206, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.09335859373502399, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.09327543154918302, \"functional effect\": 0.0431, \"times_seen\": 81.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.07171353933581678, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08319085800999117, \"functional effect\": 0.0563, \"times_seen\": 71.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.12721743171905409, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.09549041766013315, \"functional effect\": 0.0368, \"times_seen\": 30.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.05400107933001401, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08421851614782858, \"functional effect\": -0.0004, \"times_seen\": 25.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.037285570318611634, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08971965708999396, \"functional effect\": 0.0089, \"times_seen\": 17.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.5250866447018079, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.060757052886326476, \"functional effect\": -0.0977, \"times_seen\": 82.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.28302152283205956, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.07185641768338019, \"functional effect\": 0.0099, \"times_seen\": 99.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.008161377287428903, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08792661405378975, \"functional effect\": 0.1557, \"times_seen\": 5.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": 1.825517606842796, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.3098839529111563, \"functional effect\": 0.0342, \"times_seen\": 27.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.8778505798143688, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.1606655948098389, \"functional effect\": -0.1629, \"times_seen\": 16.0}, {\"site\": 207, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0362428285471489, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08526157510275024, \"functional effect\": 0.1074, \"times_seen\": 19.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.014936465222149144, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08834050020801067, \"functional effect\": -0.0533, \"times_seen\": 4.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0751601237877187, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0921062247274757, \"functional effect\": -0.2796, \"times_seen\": 16.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015197222184839385, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08651446176439609, \"functional effect\": -0.0487, \"times_seen\": 5.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.04616395012929692, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08467725993151816, \"functional effect\": 0.2323, \"times_seen\": 16.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03688508656599818, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08969475489150937, \"functional effect\": 0.1525, \"times_seen\": 10.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.08129069264290166, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.09249845245036753, \"functional effect\": 0.1284, \"times_seen\": 13.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.00052084689071428, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08746218453931297, \"functional effect\": -0.0091, \"times_seen\": 5.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.034177447388037976, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0853837241071116, \"functional effect\": 0.0282, \"times_seen\": 17.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03515741257385292, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0895874068095407, \"functional effect\": -0.4161, \"times_seen\": 4.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.02173605566293221, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08875784203415868, \"functional effect\": -0.0108, \"times_seen\": 1.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01074051134093647, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08678213170546097, \"functional effect\": 0.0509, \"times_seen\": 33.0}, {\"site\": 208, \"wildtype\": \"R\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03466975571138551, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08535459255428555, \"functional effect\": 0.0297, \"times_seen\": 8.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.02317181370538118, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.0888462170642063, \"functional effect\": -2.8369, \"times_seen\": 2.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.2400321885376176, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07402981111398764, \"functional effect\": -0.0425, \"times_seen\": 111.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.30073199365245545, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07097970323169421, \"functional effect\": -0.283, \"times_seen\": 29.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.05867521123580587, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08394610136358659, \"functional effect\": -0.0912, \"times_seen\": 81.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04980888791855387, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08446359469135525, \"functional effect\": 0.016, \"times_seen\": 28.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.5829031945776565, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.05837033473098311, \"functional effect\": -0.0477, \"times_seen\": 115.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.10807775838281831, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.0811201757348086, \"functional effect\": -0.0683, \"times_seen\": 38.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04927421153371655, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08449490349723753, \"functional effect\": 0.0731, \"times_seen\": 23.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.3705384678966738, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.11303338233883664, \"functional effect\": -0.0464, \"times_seen\": 72.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.35697212220189034, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.06826596182795983, \"functional effect\": -0.0069, \"times_seen\": 118.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.15613832111997375, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07846233201162324, \"functional effect\": -0.0198, \"times_seen\": 34.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.05036077864265595, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.084431290040527, \"functional effect\": 0.0274, \"times_seen\": 42.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.2552905865444422, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07325097434259935, \"functional effect\": -0.019, \"times_seen\": 78.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0030297048707563006, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08724719995068801, \"functional effect\": -0.0158, \"times_seen\": 65.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.002480297959064746, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.0872804317437065, \"functional effect\": 0.0711, \"times_seen\": 118.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": -2.8589000810478127, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.012051714946478104, \"functional effect\": 0.0461, \"times_seen\": 117.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.19785630927730832, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.10028228333565159, \"functional effect\": -0.0859, \"times_seen\": 81.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03947837706204519, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08507057226436995, \"functional effect\": -0.0544, \"times_seen\": 70.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.04357508819499258, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.09011164929653134, \"functional effect\": 0.043, \"times_seen\": 30.0}, {\"site\": 209, \"wildtype\": \"E\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.19842271082479052, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07619602965984901, \"functional effect\": -0.0822, \"times_seen\": 29.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0512071221214284, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08438177374376345, \"functional effect\": -2.2306, \"times_seen\": 3.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.019958051264681455, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.0862294384525046, \"functional effect\": 0.0818, \"times_seen\": 89.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.8820528470524954, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.047439397561944374, \"functional effect\": -0.1751, \"times_seen\": 43.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.07420407208797278, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08304736904157507, \"functional effect\": -0.0387, \"times_seen\": 29.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.26014360439236295, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.07300498261182757, \"functional effect\": -0.0924, \"times_seen\": 13.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.40930482326424406, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.11611185386156989, \"functional effect\": 0.1341, \"times_seen\": 45.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03912072370982683, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08509166441909921, \"functional effect\": -0.0187, \"times_seen\": 50.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01088500279742714, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08677344057646648, \"functional effect\": -0.0759, \"times_seen\": 65.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00012763005666272984, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08742287999896663, \"functional effect\": 0.1244, \"times_seen\": 35.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.034697592243683746, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08955885777752112, \"functional effect\": 0.1741, \"times_seen\": 21.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.11647494622568919, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08064938823557712, \"functional effect\": 0.0442, \"times_seen\": 165.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.13215759153953988, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.09581796195051043, \"functional effect\": -0.0042, \"times_seen\": 25.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.2761760291308781, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.10587679805429251, \"functional effect\": 0.0743, \"times_seen\": 46.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09775707023907364, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.09356024284474228, \"functional effect\": 0.048, \"times_seen\": 30.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.29255238889317686, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.07138327771005437, \"functional effect\": -0.0616, \"times_seen\": 139.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.021415364176609858, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08614237928644235, \"functional effect\": -0.0353, \"times_seen\": 162.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.11116990581126164, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.0809464959770895, \"functional effect\": -0.0405, \"times_seen\": 108.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.038879585537575305, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08510588818971568, \"functional effect\": -0.0603, \"times_seen\": 33.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.04785023077238083, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08457834352601983, \"functional effect\": 0.1366, \"times_seen\": 17.0}, {\"site\": 210, \"wildtype\": \"P\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.08780453770795417, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08226814983164353, \"functional effect\": 0.0338, \"times_seen\": 40.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": 1.0792126654045504, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.18473063110898122, \"functional effect\": -2.7538, \"times_seen\": 10.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.02196084916737188, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08877167291337941, \"functional effect\": -0.0252, \"times_seen\": 1.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.026559677478235143, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08583576268319305, \"functional effect\": 0.0406, \"times_seen\": 142.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.023253352371104014, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08603270408868463, \"functional effect\": 0.0276, \"times_seen\": 36.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.3094252756287557, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.07055328516711212, \"functional effect\": 0.0312, \"times_seen\": 120.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.00376199408660829, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08765889727084517, \"functional effect\": 0.0032, \"times_seen\": 77.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.321021377462535, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.10921960305860415, \"functional effect\": 0.0664, \"times_seen\": 203.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"H\", \"log2 fold change IC90\": -1.9497570707146117, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.0226322727027363, \"functional effect\": -0.0951, \"times_seen\": 43.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.004094039144844584, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.0876790748223192, \"functional effect\": -0.135, \"times_seen\": 52.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.06431148956494344, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.09141621112787957, \"functional effect\": 0.0204, \"times_seen\": 105.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.17176832801525754, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.09848519496666845, \"functional effect\": 0.0025, \"times_seen\": 174.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.3294933293048508, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.06957867505328967, \"functional effect\": 0.0072, \"times_seen\": 84.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.3273565648366697, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.06968180384360885, \"functional effect\": -0.0045, \"times_seen\": 43.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.10438398975989943, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.0813281358828317, \"functional effect\": -0.0316, \"times_seen\": 115.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08360720751322304, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08250784663446266, \"functional effect\": -0.0557, \"times_seen\": 81.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.058772830615056705, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08394042137659567, \"functional effect\": -0.0215, \"times_seen\": 184.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03677373837343973, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08523020473076291, \"functional effect\": 0.0276, \"times_seen\": 177.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.024820808010757634, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08593928225465175, \"functional effect\": -0.0269, \"times_seen\": 102.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.019376178744478615, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08861277577906093, \"functional effect\": -0.0171, \"times_seen\": 181.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.050998759283274436, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08439396155551876, \"functional effect\": 0.0405, \"times_seen\": 71.0}, {\"site\": 211, \"wildtype\": \"E\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.6821034998695903, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.14028044780444388, \"functional effect\": 0.066, \"times_seen\": 63.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.07465547631695273, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09207401206746037, \"functional effect\": -2.5539, \"times_seen\": 3.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.1100446640941622, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.0810096554818909, \"functional effect\": -0.1064, \"times_seen\": 201.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.10189525979719928, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08146855256286713, \"functional effect\": -0.2074, \"times_seen\": 59.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.2519161987219177, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07342250504141598, \"functional effect\": -0.0597, \"times_seen\": 127.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.255984200935244, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07321576543370091, \"functional effect\": -0.1832, \"times_seen\": 51.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.1892797039621023, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09968788876808436, \"functional effect\": -0.1224, \"times_seen\": 143.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.15458340573808604, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09731903007812574, \"functional effect\": -0.0769, \"times_seen\": 207.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.05602097551435738, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08410068554327474, \"functional effect\": 0.0437, \"times_seen\": 74.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.05936120887677018, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08390619470497182, \"functional effect\": -0.026, \"times_seen\": 35.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.10782309625406473, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09421531753280622, \"functional effect\": -0.1598, \"times_seen\": 101.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.004019419331797039, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08718736734501105, \"functional effect\": -0.1444, \"times_seen\": 34.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.048060495960491875, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09039224668600904, \"functional effect\": -0.0638, \"times_seen\": 226.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.4539112035702974, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.06382967634784695, \"functional effect\": -0.1075, \"times_seen\": 108.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.15286314841834808, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07864065771030387, \"functional effect\": -0.0803, \"times_seen\": 18.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.10393483131452398, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.093961735945627, \"functional effect\": -0.2016, \"times_seen\": 93.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -3.381447338155189, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.008389700403211598, \"functional effect\": -0.0871, \"times_seen\": 213.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.024360000830186742, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08891941993216745, \"functional effect\": -0.1353, \"times_seen\": 135.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.17349423230067676, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07752406945376801, \"functional effect\": -0.0999, \"times_seen\": 141.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.1587827624996877, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.078318643300276, \"functional effect\": -0.2008, \"times_seen\": 12.0}, {\"site\": 212, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.1087823038404316, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08108057006861885, \"functional effect\": -0.0367, \"times_seen\": 271.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.009301201977824289, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08799610935516301, \"functional effect\": -1.3884, \"times_seen\": 4.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.18532481048389182, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.09941498626737047, \"functional effect\": 0.1345, \"times_seen\": 44.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.038703790828397, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08980789806714978, \"functional effect\": 0.0486, \"times_seen\": 14.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.06714165611749684, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08345490700068642, \"functional effect\": 0.0678, \"times_seen\": 11.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -1.8060633258318481, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.025002549445476446, \"functional effect\": -0.8257, \"times_seen\": 85.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013520286916331354, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08661508143664072, \"functional effect\": -0.8349, \"times_seen\": 3.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00683751680131418, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08701722557821923, \"functional effect\": -0.7414, \"times_seen\": 2.0}, {\"site\": 213, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.014565329686051032, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.0865523629228049, \"functional effect\": -1.2806, \"times_seen\": 2.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.05314484678325042, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08426851426621976, \"functional effect\": 0.1613, \"times_seen\": 14.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05034893968255669, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08443198289850942, \"functional effect\": -0.0103, \"times_seen\": 7.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.017493165333548992, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08849719334816633, \"functional effect\": 0.2183, \"times_seen\": 4.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.025221654802215186, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08897254318680987, \"functional effect\": -0.003, \"times_seen\": 31.0}, {\"site\": 214, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0016625657554195491, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08732991708102804, \"functional effect\": -0.062, \"times_seen\": 6.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.012257758816014269, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08669091301149852, \"functional effect\": 0.0077, \"times_seen\": 64.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.1954172266128449, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.07635492995472343, \"functional effect\": 0.0328, \"times_seen\": 124.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.08404038246965838, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.09267491703980198, \"functional effect\": -0.0633, \"times_seen\": 24.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.10561956926572183, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.09407152586216402, \"functional effect\": -0.1397, \"times_seen\": 85.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01960180328064192, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.0886266351043707, \"functional effect\": -0.1498, \"times_seen\": 11.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.010560954323940015, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08679293323314415, \"functional effect\": -0.1316, \"times_seen\": 92.0}, {\"site\": 215, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.014415349087179804, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08830859648237802, \"functional effect\": -0.1756, \"times_seen\": 7.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01493707230339119, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.0865300636453802, \"functional effect\": -0.2669, \"times_seen\": 123.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.27566975310880787, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.1058396498847447, \"functional effect\": -0.1246, \"times_seen\": 136.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.029554210843412622, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.08924013814865933, \"functional effect\": -0.3667, \"times_seen\": 1.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.003854185935755778, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.0876644990742909, \"functional effect\": 0.0003, \"times_seen\": 1.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.32959917687483953, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.10987092193993848, \"functional effect\": -0.0416, \"times_seen\": 88.0}, {\"site\": 216, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.11135039702715137, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.08093636963909687, \"functional effect\": -0.0095, \"times_seen\": 40.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.018589973784952522, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.08856449889286286, \"functional effect\": 0.0326, \"times_seen\": 16.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.05855580048231691, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.09105222907123561, \"functional effect\": 0.003, \"times_seen\": 18.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.07054912527266108, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.09181231389997475, \"functional effect\": -1.1228, \"times_seen\": 2.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01986955727583429, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.08623472787319782, \"functional effect\": 0.1777, \"times_seen\": 6.0}, {\"site\": 217, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.003670352053525858, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.08720846531673297, \"functional effect\": -1.0107, \"times_seen\": 1.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0823321948683466, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08258079694219218, \"functional effect\": 0.1215, \"times_seen\": 8.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.009947954967968142, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08682981928004073, \"functional effect\": -0.343, \"times_seen\": 1.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.011410442435999845, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08674184283605312, \"functional effect\": -0.326, \"times_seen\": 20.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03809760756015329, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08977017102985384, \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.056030343603036145, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.0841001394402524, \"functional effect\": -1.9303, \"times_seen\": 18.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04885821652662323, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08451927075786374, \"functional effect\": 0.0561, \"times_seen\": 6.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06083993379025549, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08382023709625641, \"functional effect\": 0.0753, \"times_seen\": 12.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0072477509231731255, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08699248551932845, \"functional effect\": -0.2838, \"times_seen\": 5.0}, {\"site\": 218, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008488958096882373, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08691767465530063, \"functional effect\": -0.0299, \"times_seen\": 3.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.025143686974052705, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08592005096822625, \"functional effect\": -2.9784, \"times_seen\": 2.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.22444313525371937, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.07483407828712879, \"functional effect\": -0.0102, \"times_seen\": 35.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.06660912154226863, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08348571796602416, \"functional effect\": -0.4087, \"times_seen\": 43.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.2163840489937181, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.10157845882022297, \"functional effect\": -1.5791, \"times_seen\": 6.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.01924045618194997, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08860443986123649, \"functional effect\": -1.6507, \"times_seen\": 24.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.25004187477467393, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.07351795625559623, \"functional effect\": -0.2606, \"times_seen\": 66.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.00286200008974724, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08760423022305279, \"functional effect\": -2.2013, \"times_seen\": 5.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03898725227779626, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08982554530187749, \"functional effect\": 0.1774, \"times_seen\": 43.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.04751578903402775, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08459795252607973, \"functional effect\": -3.1135, \"times_seen\": 1.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.24564445328441656, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.10365968354243144, \"functional effect\": -0.1977, \"times_seen\": 61.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.014552719319889933, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08655311946644563, \"functional effect\": -0.6407, \"times_seen\": 12.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0337343797666611, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08540995042119046, \"functional effect\": -0.8643, \"times_seen\": 13.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.03675950724735546, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08968694775578674, \"functional effect\": -0.1476, \"times_seen\": 120.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.01668265651010903, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08844748941947482, \"functional effect\": -0.4284, \"times_seen\": 10.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.012910236874112737, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08665171475545075, \"functional effect\": -1.8129, \"times_seen\": 13.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.7166993092234631, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.05320047868808401, \"functional effect\": -0.2461, \"times_seen\": 124.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.4453537117335409, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.1190497138527254, \"functional effect\": 0.0355, \"times_seen\": 139.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.022328702325211558, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08879431047901548, \"functional effect\": -0.1999, \"times_seen\": 102.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.014007326609674334, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08828362460923936, \"functional effect\": -1.9779, \"times_seen\": 4.0}, {\"site\": 219, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.05753832842382771, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.0909880364072569, \"functional effect\": -1.8799, \"times_seen\": 9.0}, {\"site\": 220, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 220, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.001383481719411298, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": 0.08734681236558818, \"functional effect\": -0.2449, \"times_seen\": 1.0}, {\"site\": 220, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.025250414678216343, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": 0.08897431685674163, \"functional effect\": -1.6638, \"times_seen\": 8.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02717538237269846, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08909311327243216, \"functional effect\": -0.3753, \"times_seen\": 9.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.007586431612922095, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08697206594611938, \"functional effect\": -1.0164, \"times_seen\": 8.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.00873712530050083, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08796171064359318, \"functional effect\": -0.878, \"times_seen\": 21.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.037586554537587184, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08518219945275825, \"functional effect\": -1.3309, \"times_seen\": 6.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008979325082203803, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08688813666269261, \"functional effect\": 0.0509, \"times_seen\": 5.0}, {\"site\": 221, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0051706380092212, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08711782271706246, \"functional effect\": -0.1249, \"times_seen\": 1.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0029716289330290577, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08761088742714646, \"functional effect\": -2.1521, \"times_seen\": 13.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06956988921788097, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08331456027684679, \"functional effect\": -1.3977, \"times_seen\": 21.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.00803248635914527, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.086945179941052, \"functional effect\": -2.501, \"times_seen\": 1.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005727665705778211, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08708419282872867, \"functional effect\": -2.604, \"times_seen\": 1.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.033797078797351, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08540623861475408, \"functional effect\": -2.1988, \"times_seen\": 7.0}, {\"site\": 222, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01745135207105469, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08637939332804012, \"functional effect\": -2.4981, \"times_seen\": 4.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0038108360947403997, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08766186498677003, \"functional effect\": -0.2731, \"times_seen\": 46.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02460662710153369, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08893462185558858, \"functional effect\": 0.0083, \"times_seen\": 9.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0020316596987712235, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.0875538242816296, \"functional effect\": -0.0651, \"times_seen\": 1.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0023613488636781274, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08728762824477525, \"functional effect\": -2.1574, \"times_seen\": 1.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008659929984713205, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08690737476655948, \"functional effect\": 0.0396, \"times_seen\": 2.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0005959856604976056, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08739450369688542, \"functional effect\": -0.6241, \"times_seen\": 5.0}, {\"site\": 223, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.21751450713254855, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.10165808423860374, \"functional effect\": -0.1381, \"times_seen\": 24.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05929726711397936, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.09109903698243414, \"functional effect\": -0.1855, \"times_seen\": 28.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.11833663997612517, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08054538314498849, \"functional effect\": -0.638, \"times_seen\": 9.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.028568946091959407, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08917921387613029, \"functional effect\": -0.0408, \"times_seen\": 23.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.022074026943547202, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08877863722277281, \"functional effect\": -0.1253, \"times_seen\": 44.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03257939480091007, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08942746192260083, \"functional effect\": -0.1129, \"times_seen\": 9.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0035762223190271523, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08721415548496517, \"functional effect\": -0.0495, \"times_seen\": 10.0}, {\"site\": 224, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05397271534295906, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.09076343762337391, \"functional effect\": -0.0925, \"times_seen\": 14.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.1573588178606436, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.09750642961875568, \"functional effect\": -0.023, \"times_seen\": 23.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07376698727973184, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08307253322493119, \"functional effect\": -0.3678, \"times_seen\": 57.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 1.1878292233708077, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.19917542655377476, \"functional effect\": -0.2091, \"times_seen\": 58.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0308085795283207, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08558333842753313, \"functional effect\": 0.1782, \"times_seen\": 33.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.013158452879424213, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08663680759092257, \"functional effect\": -0.0463, \"times_seen\": 5.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0352214118699491, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.0895913810785211, \"functional effect\": -0.3219, \"times_seen\": 13.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00702040774142318, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08700619507417665, \"functional effect\": -0.3542, \"times_seen\": 2.0}, {\"site\": 225, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02530260166997563, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08591058728642692, \"functional effect\": -0.0169, \"times_seen\": 56.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.03685553476997657, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08969291762592081, \"functional effect\": -0.4365, \"times_seen\": 19.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 1.658430940281841e-05, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08743161938256687, \"functional effect\": -0.1964, \"times_seen\": 10.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01165502313499003, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08813979610707348, \"functional effect\": -1.6609, \"times_seen\": 10.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.044990100186144334, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.09020007520243183, \"functional effect\": -0.715, \"times_seen\": 5.0}, {\"site\": 226, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.026475626670747848, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08904991058900535, \"functional effect\": 0.1363, \"times_seen\": 1.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.040383932153274946, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08501719167070151, \"functional effect\": 0.2964, \"times_seen\": 9.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.004828611396211118, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.0877237294535467, \"functional effect\": -0.0536, \"times_seen\": 2.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.04391866363769987, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.0901331117926026, \"functional effect\": -1.4392, \"times_seen\": 31.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012452503291102656, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08667921169107977, \"functional effect\": -0.6773, \"times_seen\": 7.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.008061430237094045, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.0879205228833963, \"functional effect\": 0.3933, \"times_seen\": 14.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05560596697045437, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08412488159483279, \"functional effect\": -0.1116, \"times_seen\": 19.0}, {\"site\": 227, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.012686381520771938, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08820282829043272, \"functional effect\": -0.2995, \"times_seen\": 4.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.013609169805850174, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.08660974533902516, \"functional effect\": -0.6077, \"times_seen\": 2.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.6843616693796172, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.1405001928421311, \"functional effect\": -0.7924, \"times_seen\": 7.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.6697072679690954, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.027480938380900523, \"functional effect\": -0.3036, \"times_seen\": 17.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.008676262643424982, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.08795799990060499, \"functional effect\": -1.1128, \"times_seen\": 5.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.052413966093495995, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.0843112161760264, \"functional effect\": 0.1064, \"times_seen\": 24.0}, {\"site\": 228, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.07256158072997992, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.09194047481825962, \"functional effect\": 0.2946, \"times_seen\": 7.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0008149890305811718, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.08748001847937384, \"functional effect\": -0.0781, \"times_seen\": 19.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.20208500136160654, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.07600285085050715, \"functional effect\": -0.0445, \"times_seen\": 60.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.862365910975769, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.0480911899828976, \"functional effect\": -0.2295, \"times_seen\": 42.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.019220184371785097, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.08627355180947119, \"functional effect\": -1.2574, \"times_seen\": 6.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.040343922611521574, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.0850195494427531, \"functional effect\": -0.8465, \"times_seen\": 16.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0356375032404335, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.089617224084664, \"functional effect\": 0.1679, \"times_seen\": 35.0}, {\"site\": 229, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.1281401501178768, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.0799999105005558, \"functional effect\": 0.1446, \"times_seen\": 31.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0021459777245275034, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.08756076225300813, \"functional effect\": 0.1623, \"times_seen\": 2.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.003959218424684303, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.08719100558314595, \"functional effect\": -0.4334, \"times_seen\": 7.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -1.329457836088323, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.03479019342525399, \"functional effect\": -0.4892, \"times_seen\": 12.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.012588399343236523, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.08819683810438043, \"functional effect\": 0.0266, \"times_seen\": 10.0}, {\"site\": 230, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.023667924466973814, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.0860079853273824, \"functional effect\": -1.2702, \"times_seen\": 6.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.003908617429290815, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08719406376863906, \"functional effect\": -3.2703, \"times_seen\": 1.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.011102516976634553, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08676035878828801, \"functional effect\": 0.1887, \"times_seen\": 15.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.061968976051829286, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.0837546656718785, \"functional effect\": 0.2882, \"times_seen\": 10.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.9587599603317329, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.044982959323991815, \"functional effect\": 0.0597, \"times_seen\": 27.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.02388742712860444, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08599490040988958, \"functional effect\": 0.4295, \"times_seen\": 9.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04171795096501769, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08493861504128973, \"functional effect\": -0.0906, \"times_seen\": 2.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04732086464912048, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08460938343659767, \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 231, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.09161098788043755, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08205137715575807, \"functional effect\": 0.2545, \"times_seen\": 23.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.0007589187866858417, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08747661864051838, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.020965657264402283, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08871045804549603, \"functional effect\": -0.9604, \"times_seen\": 2.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.05164314955403042, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.0906169972627616, \"functional effect\": -0.5704, \"times_seen\": 15.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010010861073573614, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08682603330549642, \"functional effect\": -0.2026, \"times_seen\": 3.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02223668450618595, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08609335274224392, \"functional effect\": -1.1048, \"times_seen\": 7.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.12411253385124152, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.09528512882843118, \"functional effect\": -1.0273, \"times_seen\": 10.0}, {\"site\": 232, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.014856940408176153, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08833563080177781, \"functional effect\": -0.665, \"times_seen\": 3.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.00023699391759778949, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08744497788215208, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.022476565572479387, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08880341156244655, \"functional effect\": 0.0943, \"times_seen\": 2.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05514579902779283, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.09083726917076239, \"functional effect\": -0.123, \"times_seen\": 4.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.003351676513177112, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08763396970774448, \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.015609195257072384, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08838170307086797, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.016380717317037434, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08644351991178416, \"functional effect\": -0.1354, \"times_seen\": 4.0}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 233, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.034900824807678865, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.0853409228398687, \"functional effect\": 0.3651, \"times_seen\": 8.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.02216334436890621, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08878413368913712, \"functional effect\": -0.1122, \"times_seen\": 16.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.009305757970220045, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08799638724496422, \"functional effect\": -0.0881, \"times_seen\": 35.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.056182198246113355, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.09090254803810938, \"functional effect\": -0.0887, \"times_seen\": 56.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.13313062814070076, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.07972365802133054, \"functional effect\": -0.1069, \"times_seen\": 60.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07299551711818263, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08311696750739868, \"functional effect\": 0.0239, \"times_seen\": 59.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.008819583328165459, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08689775784485537, \"functional effect\": 0.1662, \"times_seen\": 2.0}, {\"site\": 234, \"wildtype\": \"R\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03484863070734681, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08534401037613797, \"functional effect\": -0.2899, \"times_seen\": 17.0}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.08558641592072701, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.09277428337563605, \"functional effect\": -0.1208, \"times_seen\": 15.0}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.014372292931680552, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.088305961017628, \"functional effect\": -0.2954, \"times_seen\": 13.0}, {\"site\": 235, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0024433316876835464, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.08728266816468984, \"functional effect\": -2.7351, \"times_seen\": 1.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.15537627308389107, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.09737252876331182, \"functional effect\": -3.0623, \"times_seen\": 1.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.016237274090347732, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08645211518211333, \"functional effect\": -0.0871, \"times_seen\": 6.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.012983300425204696, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08822098305048581, \"functional effect\": -0.1024, \"times_seen\": 20.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02220089338568126, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08609548861690754, \"functional effect\": 0.0548, \"times_seen\": 14.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03690986195710053, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08522216332682492, \"functional effect\": -0.0449, \"times_seen\": 21.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.18752491235394406, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.07677377691421662, \"functional effect\": -0.018, \"times_seen\": 77.0}, {\"site\": 236, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005793028928202609, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08708024745263604, \"functional effect\": 0.1525, \"times_seen\": 2.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.038525397105564484, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08512678465135826, \"functional effect\": -0.0885, \"times_seen\": 13.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.08861406010847697, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08222200062678953, \"functional effect\": -0.0874, \"times_seen\": 49.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.010393455236578968, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08806275575461447, \"functional effect\": -0.169, \"times_seen\": 2.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.03146198679063102, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08554458587642433, \"functional effect\": -0.4746, \"times_seen\": 8.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0016403814642703732, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08733125996164177, \"functional effect\": -0.0441, \"times_seen\": 5.0}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 237, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004456636126911912, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08716094872941875, \"functional effect\": -0.0511, \"times_seen\": 10.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.03217670100301586, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08550221740099455, \"functional effect\": -0.0169, \"times_seen\": 26.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.008256832342623678, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08693166060064697, \"functional effect\": -0.4513, \"times_seen\": 7.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.013030429837397812, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08822386506703812, \"functional effect\": -0.0413, \"times_seen\": 2.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.019660442134607995, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08624722829343126, \"functional effect\": -0.1915, \"times_seen\": 2.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.005158421452947654, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08711856042271722, \"functional effect\": -0.4464, \"times_seen\": 8.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006159951067350808, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.0870581030583178, \"functional effect\": -1.983, \"times_seen\": 2.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005179180779609854, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08711730685935747, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03230645506886218, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08941054497336584, \"functional effect\": 0.077, \"times_seen\": 15.0}, {\"site\": 238, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012351760852336554, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.0866852646543327, \"functional effect\": -0.453, \"times_seen\": 5.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.025225594840984564, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08591517306393548, \"functional effect\": -0.0762, \"times_seen\": 14.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.007309984607185598, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08787474031135033, \"functional effect\": 0.1729, \"times_seen\": 13.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.01730725065353687, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08848578978272172, \"functional effect\": -0.3791, \"times_seen\": 8.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.007103305873188078, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.0870011957890876, \"functional effect\": -0.1038, \"times_seen\": 7.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013860770526603582, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08659464223427829, \"functional effect\": 0.1964, \"times_seen\": 3.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.019642561609280008, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.0886291389769452, \"functional effect\": -0.1182, \"times_seen\": 9.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.08062340972628346, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.09245567947101606, \"functional effect\": -0.1558, \"times_seen\": 6.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.010676172660157893, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08808001464462883, \"functional effect\": -0.0741, \"times_seen\": 5.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01914733426629451, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08627790837538363, \"functional effect\": -0.0102, \"times_seen\": 4.0}, {\"site\": 239, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.001661623340624205, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08753137051085509, \"functional effect\": 0.0411, \"times_seen\": 3.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.022761835867077477, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08606201984629604, \"functional effect\": 0.0648, \"times_seen\": 23.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.022708610579866974, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08881769597112366, \"functional effect\": -0.003, \"times_seen\": 27.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0484603615521728, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08454258202489759, \"functional effect\": -0.5302, \"times_seen\": 13.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 2.05341787822728, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.36291415275414923, \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -8.662140453791324e-05, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08742536503241147, \"functional effect\": 0.1752, \"times_seen\": 4.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.08838109970164931, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.09295417314029855, \"functional effect\": -0.1026, \"times_seen\": 14.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05933830048369147, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.0839075270526243, \"functional effect\": 0.0128, \"times_seen\": 56.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.46730579210745365, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.06323979732251538, \"functional effect\": -0.0384, \"times_seen\": 93.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.07348758429830976, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08308862322352664, \"functional effect\": -0.0605, \"times_seen\": 48.0}, {\"site\": 240, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.013063687210393221, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08664249865137331, \"functional effect\": -0.0469, \"times_seen\": 12.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0218984259101124, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08611354081391905, \"functional effect\": 0.0433, \"times_seen\": 14.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.010190170077689664, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08681524258281059, \"functional effect\": 0.1124, \"times_seen\": 2.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.022394135398701054, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08608395731550986, \"functional effect\": -0.1492, \"times_seen\": 9.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.012329246052608683, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08668661748119284, \"functional effect\": -0.0313, \"times_seen\": 6.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.7689911172196207, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.025653353257649607, \"functional effect\": 0.0693, \"times_seen\": 8.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.002022313795930855, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08730814335271624, \"functional effect\": 0.1182, \"times_seen\": 23.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.015606885920714438, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08648989884215548, \"functional effect\": -0.3063, \"times_seen\": 1.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03096086457379086, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08557430507371953, \"functional effect\": -0.2637, \"times_seen\": 10.0}, {\"site\": 241, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.005497194891724155, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08709810565677016, \"functional effect\": 0.1729, \"times_seen\": 9.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.09014951376936974, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.09306818355205303, \"functional effect\": 0.1197, \"times_seen\": 15.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.006430356375750284, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08704178722820363, \"functional effect\": -0.1089, \"times_seen\": 5.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.025086242350886523, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.0889641925482942, \"functional effect\": -0.628, \"times_seen\": 12.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04803920958990971, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.09039091299551213, \"functional effect\": -0.0195, \"times_seen\": 11.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.004754196796878709, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08771920475661422, \"functional effect\": -0.0842, \"times_seen\": 13.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016260453227994305, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.0864507262057024, \"functional effect\": 0.1609, \"times_seen\": 2.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.023794349659112618, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08600044866901481, \"functional effect\": -0.0004, \"times_seen\": 17.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03701696732364678, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08521583668677311, \"functional effect\": -0.1595, \"times_seen\": 6.0}, {\"site\": 242, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.13582227401148056, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.07957505572197426, \"functional effect\": -0.022, \"times_seen\": 66.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.03159541491511871, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08936648935391824, \"functional effect\": 0.0957, \"times_seen\": 8.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.012797942393805965, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08665845969301904, \"functional effect\": 0.0858, \"times_seen\": 12.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.19202248849253972, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.099877591002564, \"functional effect\": 0.1092, \"times_seen\": 62.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0022206755152449523, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08729613984373538, \"functional effect\": -0.0162, \"times_seen\": 42.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.047967311609900386, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.0903864083968726, \"functional effect\": -0.0306, \"times_seen\": 46.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.00880322718549886, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08689874302893193, \"functional effect\": 0.169, \"times_seen\": 9.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.00911855394158582, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08798496957942088, \"functional effect\": 0.1541, \"times_seen\": 7.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.9629185313553434, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.17042405372973893, \"functional effect\": 0.0437, \"times_seen\": 57.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.12775629266917796, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.0800211988853785, \"functional effect\": -0.0659, \"times_seen\": 25.0}, {\"site\": 243, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.016197163821509614, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08841773026463608, \"functional effect\": 0.0583, \"times_seen\": 29.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.098841361287701, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.0936305866545928, \"functional effect\": -0.0932, \"times_seen\": 11.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.026692877171598357, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08906332131950292, \"functional effect\": 0.0591, \"times_seen\": 7.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.024146906174227305, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08890628697381832, \"functional effect\": 0.2911, \"times_seen\": 2.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.7175014976211036, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.1437649450479746, \"functional effect\": -0.0707, \"times_seen\": 20.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.06763600434411515, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08342631556823274, \"functional effect\": -0.0197, \"times_seen\": 36.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04468564578718225, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08476407170645252, \"functional effect\": -0.0213, \"times_seen\": 32.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01978264854203251, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08863774536061678, \"functional effect\": -0.0426, \"times_seen\": 11.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04712335787551249, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.0846209673609833, \"functional effect\": -0.0617, \"times_seen\": 8.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006310167705169988, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08704903884560748, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 244, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0006749117601601253, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08747152509235662, \"functional effect\": 0.0067, \"times_seen\": 2.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.008520326542746506, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08691578482920834, \"functional effect\": -1.6307, \"times_seen\": 2.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.09753782210748312, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.0935460254604396, \"functional effect\": 0.0923, \"times_seen\": 14.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.06679849240954397, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08347476019268742, \"functional effect\": -0.1126, \"times_seen\": 48.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0021213305212921915, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08755926636551511, \"functional effect\": -0.12, \"times_seen\": 17.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.09100676879791916, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08208574851603177, \"functional effect\": 0.0527, \"times_seen\": 61.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.014159766378976812, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08829295343204421, \"functional effect\": -0.3252, \"times_seen\": 4.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.008995598358300909, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08797747126414154, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.12571745503733148, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.09539118742689141, \"functional effect\": -0.0493, \"times_seen\": 17.0}, {\"site\": 245, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.019153241772079423, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.0885990836701188, \"functional effect\": 0.0026, \"times_seen\": 12.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.1006680739053503, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08153788086082582, \"functional effect\": 0.0119, \"times_seen\": 23.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.08740012377294851, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.09289098943938985, \"functional effect\": -0.0304, \"times_seen\": 15.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.011850531093050978, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08815174125052466, \"functional effect\": 0.054, \"times_seen\": 34.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01371113110096271, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08660362448222247, \"functional effect\": -0.1483, \"times_seen\": 2.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.5105352275511787, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.06137296606820467, \"functional effect\": 0.0215, \"times_seen\": 3.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.056320598343231554, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08408322109782036, \"functional effect\": 0.0081, \"times_seen\": 15.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.019030736537975074, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08628488158480094, \"functional effect\": -0.042, \"times_seen\": 5.0}, {\"site\": 246, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.012619174270156087, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08819871950004625, \"functional effect\": 0.1009, \"times_seen\": 4.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.03853523165028398, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08979740585586411, \"functional effect\": 0.0723, \"times_seen\": 38.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.7341578830842093, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.14543437681908544, \"functional effect\": -0.0908, \"times_seen\": 31.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.025999385108848083, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.0858691047697341, \"functional effect\": -0.2072, \"times_seen\": 6.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.10556246260105956, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.0812617297038552, \"functional effect\": -0.0007, \"times_seen\": 63.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.009768084018172451, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08802459108578486, \"functional effect\": 0.3528, \"times_seen\": 6.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03018517259808951, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08927917580200469, \"functional effect\": 0.0803, \"times_seen\": 5.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.08001332453338734, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.09241659018692691, \"functional effect\": 0.0791, \"times_seen\": 48.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0050604764958158445, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.0877378292496037, \"functional effect\": 0.0563, \"times_seen\": 12.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014580679020336723, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08655144206701293, \"functional effect\": 0.0533, \"times_seen\": 7.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004413015558862723, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08716358412183772, \"functional effect\": -0.5234, \"times_seen\": 2.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02300757501104581, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08604736185870054, \"functional effect\": 0.3226, \"times_seen\": 11.0}, {\"site\": 247, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.0009684117743304722, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08748932199657662, \"functional effect\": -0.0369, \"times_seen\": 23.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.24739104891576097, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.07365316324267124, \"functional effect\": -0.0713, \"times_seen\": 45.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.030021383519686383, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08563004909337636, \"functional effect\": -0.0358, \"times_seen\": 27.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.016629108575123987, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08642863806514127, \"functional effect\": -0.4598, \"times_seen\": 4.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03885918705365651, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08981757201735877, \"functional effect\": -0.0942, \"times_seen\": 18.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.8689785585601053, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.15968059480443977, \"functional effect\": -0.0788, \"times_seen\": 39.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004607360690615584, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.0871518431254166, \"functional effect\": -0.1832, \"times_seen\": 2.0}, {\"site\": 248, \"wildtype\": \"P\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.023856763721992868, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08599672818675572, \"functional effect\": 0.2736, \"times_seen\": 11.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.02916428699848163, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08921602206392001, \"functional effect\": -2.368, \"times_seen\": 1.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0044313633028490096, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08716247560970473, \"functional effect\": 0.0209, \"times_seen\": 25.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.08055480984262439, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08268259830649205, \"functional effect\": -0.0529, \"times_seen\": 37.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01982367248324571, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08623747060497047, \"functional effect\": 0.2515, \"times_seen\": 11.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.2419700277487047, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.2067920135673018, \"functional effect\": -0.3223, \"times_seen\": 10.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.017217222296397657, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08639341266577226, \"functional effect\": 0.1264, \"times_seen\": 5.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.22326876328353817, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.10206436191738401, \"functional effect\": 0.0234, \"times_seen\": 21.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04620419169963502, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.09027601449304617, \"functional effect\": 0.0032, \"times_seen\": 18.0}, {\"site\": 249, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003482215863940703, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08721983857146552, \"functional effect\": 0.0587, \"times_seen\": 40.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.010505315929652079, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08679628051889891, \"functional effect\": -1.3579, \"times_seen\": 1.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.18874774655626694, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.07670873071830013, \"functional effect\": -0.0694, \"times_seen\": 139.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.13827901917430113, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.09622538613268465, \"functional effect\": -0.0911, \"times_seen\": 21.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.01665579090550166, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08844584238175202, \"functional effect\": 0.0047, \"times_seen\": 30.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.06912383161514835, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.0917216537911514, \"functional effect\": -0.19, \"times_seen\": 36.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.026406794379579244, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.085844859222894, \"functional effect\": -0.0226, \"times_seen\": 68.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.07050024044872287, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.083260850508431, \"functional effect\": 0.0066, \"times_seen\": 47.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.005443170405549649, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08776110595444082, \"functional effect\": -0.1172, \"times_seen\": 25.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -2.9831696288428033, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.01105706823048324, \"functional effect\": -0.0792, \"times_seen\": 18.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.016289336601351217, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08644899544241842, \"functional effect\": -0.2095, \"times_seen\": 34.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.018607856458791826, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08631017695542013, \"functional effect\": -0.0103, \"times_seen\": 6.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.45048244854793634, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.11947368510594247, \"functional effect\": 0.048, \"times_seen\": 86.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03445330023177187, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08536739973446043, \"functional effect\": -0.0621, \"times_seen\": 48.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03357531987585262, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08541936755089073, \"functional effect\": -0.0404, \"times_seen\": 14.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3029323143871839, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.07087153132311652, \"functional effect\": -0.1955, \"times_seen\": 43.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.030146109857270762, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.0856226463780107, \"functional effect\": -0.0687, \"times_seen\": 85.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.9617935310221164, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.04488847253592667, \"functional effect\": -0.1012, \"times_seen\": 52.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.26325847336266855, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.10493303326594576, \"functional effect\": -0.0993, \"times_seen\": 47.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.8060966654195909, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.05000394332441133, \"functional effect\": -0.2328, \"times_seen\": 15.0}, {\"site\": 250, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.1481885775162652, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.0788958797249211, \"functional effect\": 0.0098, \"times_seen\": 89.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.006016612028619372, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08779599612366523, \"functional effect\": -0.0229, \"times_seen\": 43.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 2.106617671450818, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.37654652018101803, \"functional effect\": -0.247, \"times_seen\": 19.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.006030089817352462, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08779681632570453, \"functional effect\": 0.2769, \"times_seen\": 12.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.025622429251591226, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08589154408657834, \"functional effect\": -0.1792, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04494759378993787, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08474868261657002, \"functional effect\": -0.0267, \"times_seen\": 55.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.06596896745485548, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08352277055225114, \"functional effect\": 0.1268, \"times_seen\": 17.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.002500012323000568, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08727923906861533, \"functional effect\": 0.0095, \"times_seen\": 14.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -2.328867209550826, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.017402219568656806, \"functional effect\": -0.1429, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.030493699693895718, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08560201972035243, \"functional effect\": 0.1052, \"times_seen\": 10.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.018046034150556202, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08853111369401888, \"functional effect\": 0.0779, \"times_seen\": 47.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0038126536110335775, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08719986385344389, \"functional effect\": 0.1178, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.026411711483357442, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08584456664036594, \"functional effect\": 0.2366, \"times_seen\": 13.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.07732313568779746, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08286801705616238, \"functional effect\": -0.0124, \"times_seen\": 98.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.003791868295374275, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08766071246202324, \"functional effect\": 0.1581, \"times_seen\": 9.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3940499575346448, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.06653385278948948, \"functional effect\": -0.0805, \"times_seen\": 23.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.4087041828056185, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.06586145359615943, \"functional effect\": 0.0369, \"times_seen\": 72.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0452733748373074, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.0847295473199704, \"functional effect\": -0.0644, \"times_seen\": 34.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0008190316769317158, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08748026361175659, \"functional effect\": -0.0808, \"times_seen\": 11.0}, {\"site\": 251, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.017307249555319863, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08638802170008558, \"functional effect\": 0.0042, \"times_seen\": 51.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.002116397346905287, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08730244984709842, \"functional effect\": -2.7623, \"times_seen\": 2.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.10968358602713593, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.09433689534557722, \"functional effect\": 0.022, \"times_seen\": 34.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0046212110411928, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08771111928687342, \"functional effect\": -0.1201, \"times_seen\": 9.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.05034481516163526, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.0905354843738152, \"functional effect\": 0.2949, \"times_seen\": 17.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0014323400001521362, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08734385433031616, \"functional effect\": -0.1349, \"times_seen\": 10.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.12955707908872927, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.09564540201478557, \"functional effect\": -0.09, \"times_seen\": 63.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.004883709063436514, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08713515078030645, \"functional effect\": 0.0354, \"times_seen\": 16.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.018237689907588808, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08633232525338744, \"functional effect\": -0.2111, \"times_seen\": 9.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.031512089757816095, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08554161507314706, \"functional effect\": 0.0747, \"times_seen\": 19.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.007571074356952398, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08697299175465827, \"functional effect\": 0.1087, \"times_seen\": 11.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.272526488625364, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.03619052527802157, \"functional effect\": -0.0646, \"times_seen\": 45.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.01499089690889034, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.0865268354096632, \"functional effect\": -0.1899, \"times_seen\": 5.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.01952908844012369, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08862216824959547, \"functional effect\": -0.2301, \"times_seen\": 8.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.29288888692572734, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.07136663002585199, \"functional effect\": 0.0354, \"times_seen\": 94.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -4.101755519301766e-06, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08743036575436605, \"functional effect\": 0.3266, \"times_seen\": 4.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006911566619672496, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08701275932291136, \"functional effect\": -0.222, \"times_seen\": 16.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -1.4695888421210743, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.03156990006950493, \"functional effect\": 0.0208, \"times_seen\": 45.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01730482530416557, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08848564102725492, \"functional effect\": -0.0605, \"times_seen\": 16.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.022493616199990157, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.0888044611001499, \"functional effect\": -0.1098, \"times_seen\": 9.0}, {\"site\": 252, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01635713816830552, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08842753507610907, \"functional effect\": 0.0438, \"times_seen\": 43.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.024420976573380427, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08596310294279932, \"functional effect\": 0.2278, \"times_seen\": 9.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0022149650206279166, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08729648538115606, \"functional effect\": -0.0983, \"times_seen\": 1.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.00960015978857498, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08685075414991573, \"functional effect\": -0.1115, \"times_seen\": 2.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.05534160285690757, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.09084959852080901, \"functional effect\": -0.0324, \"times_seen\": 27.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.11414732148777826, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08077961189406435, \"functional effect\": 0.0483, \"times_seen\": 40.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.018337074388519028, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08632637819072805, \"functional effect\": -0.3463, \"times_seen\": 12.0}, {\"site\": 253, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01651519337029507, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08643546274010114, \"functional effect\": 0.3442, \"times_seen\": 5.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.014692508667839452, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08654473334350522, \"functional effect\": -3.1202, \"times_seen\": 2.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.016620570700027145, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08844368319867439, \"functional effect\": 0.0133, \"times_seen\": 21.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.11764292772556417, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.09485878987085342, \"functional effect\": -0.1041, \"times_seen\": 14.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.14426272360468462, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.07911086313761878, \"functional effect\": -0.0256, \"times_seen\": 54.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.006517239623420775, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08703654547909469, \"functional effect\": 0.0481, \"times_seen\": 12.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04398127475204846, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08480546641057671, \"functional effect\": 0.0854, \"times_seen\": 10.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.06956252653161676, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0917495487658268, \"functional effect\": 0.2371, \"times_seen\": 9.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02028314795719642, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0862100097123927, \"functional effect\": -0.104, \"times_seen\": 6.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012877185495923092, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0866536999230157, \"functional effect\": -0.1809, \"times_seen\": 10.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.014037611386069803, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08828547786153278, \"functional effect\": 0.0541, \"times_seen\": 16.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.015193257363002175, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08835622575261134, \"functional effect\": 0.1249, \"times_seen\": 8.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.02385985929441373, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08888859942871218, \"functional effect\": 0.0088, \"times_seen\": 18.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.3418758682240797, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.11080986380503167, \"functional effect\": -0.0566, \"times_seen\": 18.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.00957494412698926, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08685227215496998, \"functional effect\": 0.1361, \"times_seen\": 3.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.06105792680432841, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08380757271106164, \"functional effect\": -0.0423, \"times_seen\": 21.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.38830663580783936, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.11443410435435315, \"functional effect\": -0.0097, \"times_seen\": 41.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -1.067717138733943, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.041710811982442975, \"functional effect\": -0.021, \"times_seen\": 13.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.02094443637550358, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0887091531952845, \"functional effect\": -0.0902, \"times_seen\": 27.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.033239052098761546, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08543927967909952, \"functional effect\": -0.2542, \"times_seen\": 10.0}, {\"site\": 254, \"wildtype\": \"G\", \"mutant\": \"Y\", \"log2 fold change IC90\": 7.609525356342542e-05, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08743522599753904, \"functional effect\": -0.3191, \"times_seen\": 5.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.0408993269734165, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08994467444148764, \"functional effect\": -1.9373, \"times_seen\": 5.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.005872441637497137, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08778722299398913, \"functional effect\": 0.0905, \"times_seen\": 42.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0002809300174078744, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08741359098661333, \"functional effect\": -0.1519, \"times_seen\": 6.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0412317307824317, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08496724606021053, \"functional effect\": 0.2637, \"times_seen\": 10.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0191516740271962, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08627764884379886, \"functional effect\": -0.1184, \"times_seen\": 15.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.039500486095196644, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.0898575061164694, \"functional effect\": -0.1066, \"times_seen\": 52.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02496853730708573, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08895693452998447, \"functional effect\": -0.0135, \"times_seen\": 7.0}, {\"site\": 255, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.022969514635484557, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08604963194213155, \"functional effect\": -0.0462, \"times_seen\": 21.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.30929746887011533, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.07055953568150093, \"functional effect\": 0.0035, \"times_seen\": 53.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.026268492401460553, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08585308901685228, \"functional effect\": 0.1198, \"times_seen\": 19.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005274509535041254, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08711155061161759, \"functional effect\": 0.3663, \"times_seen\": 1.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.015204088570627817, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08835688910015983, \"functional effect\": 0.0819, \"times_seen\": 8.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01121519003116182, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08675358315474185, \"functional effect\": 0.059, \"times_seen\": 11.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06258524222487498, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08371889640439903, \"functional effect\": 0.377, \"times_seen\": 5.0}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 256, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.008769198302973957, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08796366616949625, \"functional effect\": -0.159, \"times_seen\": 3.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.4121951422083012, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.03285113904580509, \"functional effect\": 0.0856, \"times_seen\": 52.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.004254562785899019, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08717315791927764, \"functional effect\": 0.0222, \"times_seen\": 2.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.012239636384753583, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08669200198729372, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.05112789970579582, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08438640750995052, \"functional effect\": 0.181, \"times_seen\": 14.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02415525699864074, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08597893732373064, \"functional effect\": -0.042, \"times_seen\": 6.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.014536142024653252, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08655411401125088, \"functional effect\": 0.1285, \"times_seen\": 9.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04299910299894579, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08486322074560647, \"functional effect\": -0.131, \"times_seen\": 36.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.37341915661877667, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.11325930623848908, \"functional effect\": 0.0958, \"times_seen\": 46.0}, {\"site\": 257, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.19494748701507636, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.07637979506676361, \"functional effect\": 0.0007, \"times_seen\": 71.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.011514971559145444, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08673555826443516, \"functional effect\": -2.9356, \"times_seen\": 2.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.7579861960280481, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.14785639436729103, \"functional effect\": -0.0449, \"times_seen\": 78.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.18831210457842043, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07673189749171827, \"functional effect\": 0.0783, \"times_seen\": 58.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.7428649076325861, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.05224429944900565, \"functional effect\": 0.0359, \"times_seen\": 73.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.1229968359161695, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08028562507464439, \"functional effect\": -0.1557, \"times_seen\": 30.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.10579975143599238, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08124836519163928, \"functional effect\": 0.0559, \"times_seen\": 31.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.23630782927376826, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.10299099995212647, \"functional effect\": -0.0955, \"times_seen\": 20.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.1471919009692466, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07895040326509223, \"functional effect\": 0.0601, \"times_seen\": 23.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.1389049271606235, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.0397026033263297, \"functional effect\": 0.067, \"times_seen\": 5.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.5062310537125976, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.12418074525074457, \"functional effect\": 0.0457, \"times_seen\": 58.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.028411041750794876, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08572568304800143, \"functional effect\": -0.0449, \"times_seen\": 9.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -1.8534020435799041, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.024195462092721852, \"functional effect\": 0.0278, \"times_seen\": 29.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.2580721214203558, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.10455648618730737, \"functional effect\": -0.047, \"times_seen\": 37.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0016526454520836638, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08753082580499501, \"functional effect\": 0.3115, \"times_seen\": 12.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.17098519172380758, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07765901153711774, \"functional effect\": -0.0097, \"times_seen\": 93.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.13560473507379125, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.0960471810001238, \"functional effect\": 0.0399, \"times_seen\": 92.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.22743545905113338, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07467902422455772, \"functional effect\": -0.0641, \"times_seen\": 34.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.1429877788026557, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07918080623793482, \"functional effect\": 0.0049, \"times_seen\": 61.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.1055445657219168, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08126273777578646, \"functional effect\": -0.0953, \"times_seen\": 10.0}, {\"site\": 258, \"wildtype\": \"G\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01149581661360743, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08673670987713028, \"functional effect\": -0.0368, \"times_seen\": 28.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.016789839217638883, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08641900958765701, \"functional effect\": -2.1507, \"times_seen\": 3.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.12060474202944754, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.09505373246497066, \"functional effect\": 0.1069, \"times_seen\": 32.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 1.2338932711234878, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.20563754765578313, \"functional effect\": 0.0076, \"times_seen\": 35.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.03936141427221358, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08984884451819093, \"functional effect\": 0.0609, \"times_seen\": 17.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.04553103309524798, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.09023390171188936, \"functional effect\": 0.0082, \"times_seen\": 17.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.017868982291599826, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08635439190837915, \"functional effect\": 0.0203, \"times_seen\": 31.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.016682454530880794, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08642544228714923, \"functional effect\": -0.0365, \"times_seen\": 17.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.05155407057569071, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.0843614835194495, \"functional effect\": 0.0746, \"times_seen\": 13.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.018895954473577583, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08629294302356443, \"functional effect\": 0.1179, \"times_seen\": 14.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05093008004259613, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08439797921066891, \"functional effect\": 0.0299, \"times_seen\": 46.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.00857832910848777, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08691229050986835, \"functional effect\": 0.0169, \"times_seen\": 10.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.008215024728542618, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08693417981494779, \"functional effect\": 0.0233, \"times_seen\": 10.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.13475312061829772, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.07963404911352472, \"functional effect\": -0.0905, \"times_seen\": 56.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.031018700298620444, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08933077240803117, \"functional effect\": 0.066, \"times_seen\": 7.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.1773362641271518, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.09886602306218326, \"functional effect\": 0.102, \"times_seen\": 43.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.4468763100818551, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.03207084188202024, \"functional effect\": 0.0822, \"times_seen\": 96.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06841967183248315, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08338101095717483, \"functional effect\": 0.012, \"times_seen\": 76.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.29905635404276765, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.07106219155793173, \"functional effect\": -0.0147, \"times_seen\": 84.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.05516966186829391, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08415032679612193, \"functional effect\": 0.0732, \"times_seen\": 15.0}, {\"site\": 259, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": 1.0462880289971013, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.18056252145578214, \"functional effect\": 0.2595, \"times_seen\": 16.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.021287574030639907, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08615000989059778, \"functional effect\": -0.0939, \"times_seen\": 7.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.10334460863165229, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08138674936971146, \"functional effect\": -0.0353, \"times_seen\": 12.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.02146241548022663, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08874100867145385, \"functional effect\": -0.055, \"times_seen\": 5.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.001808500139780533, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.0873210837567491, \"functional effect\": -0.1135, \"times_seen\": 5.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0033317640883169805, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08722893478616765, \"functional effect\": 0.2737, \"times_seen\": 3.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03960938116561163, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.0850628477711363, \"functional effect\": -0.0926, \"times_seen\": 8.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.04210276007962478, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.09001973365634174, \"functional effect\": -0.3805, \"times_seen\": 3.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.06708913706028831, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.09159238599505233, \"functional effect\": 0.0867, \"times_seen\": 15.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.3316908022847939, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.11003032879659212, \"functional effect\": -0.1126, \"times_seen\": 72.0}, {\"site\": 260, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.08694450679459727, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08231720680015926, \"functional effect\": -0.1314, \"times_seen\": 57.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.002949000140200214, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.08725208071794159, \"functional effect\": -0.0692, \"times_seen\": 25.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.03290229120756586, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.0894474793462068, \"functional effect\": -0.1399, \"times_seen\": 1.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.936756759438049, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.16736144356979435, \"functional effect\": -0.3907, \"times_seen\": 4.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.3310686366982414, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.10998288819196123, \"functional effect\": 0.007, \"times_seen\": 45.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.5157864825721004, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.0611499811292336, \"functional effect\": -0.1058, \"times_seen\": 39.0}, {\"site\": 261, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 1.132462418977943, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.1916764189868999, \"functional effect\": -0.1244, \"times_seen\": 29.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.004381592539051771, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.08716548263315259, \"functional effect\": -3.1472, \"times_seen\": 1.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.22076746486956256, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.07502498218462586, \"functional effect\": 0.0624, \"times_seen\": 41.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.024765102285042688, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.08594260062920449, \"functional effect\": 0.0345, \"times_seen\": 26.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.05716299236921582, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.09096436775408201, \"functional effect\": -0.1187, \"times_seen\": 15.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0767254004292231, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.09220621118136564, \"functional effect\": -0.2799, \"times_seen\": 5.0}, {\"site\": 262, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.015534967267201319, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.0864942104894084, \"functional effect\": -0.6806, \"times_seen\": 13.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.002465681636710979, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.08758016803135327, \"functional effect\": -0.254, \"times_seen\": 3.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.023356715067200173, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.08885760466784479, \"functional effect\": -0.2097, \"times_seen\": 24.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.05557860720220336, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.0908645244183205, \"functional effect\": -0.1006, \"times_seen\": 8.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.004362263787346892, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.08716665045532536, \"functional effect\": -0.1918, \"times_seen\": 1.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.044018612664695034, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.09013935637557735, \"functional effect\": -0.548, \"times_seen\": 3.0}, {\"site\": 263, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004342426612026281, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.08716784901216942, \"functional effect\": -0.0664, \"times_seen\": 1.0}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.012940472237038689, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.08664989876626669, \"functional effect\": -0.3599, \"times_seen\": 38.0}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.07415923454030308, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.08304995011250611, \"functional effect\": -0.3533, \"times_seen\": 31.0}, {\"site\": 264, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.008653247844819011, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08690777729693801, \"functional effect\": -2.9919, \"times_seen\": 3.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.021737602194238103, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08612314081334214, \"functional effect\": -2.289, \"times_seen\": 4.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01096911192432918, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08676838183198274, \"functional effect\": -2.2112, \"times_seen\": 1.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.3604696797646957, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.06810066359273442, \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 265, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.008567907761668523, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08691291832542737, \"functional effect\": -2.8801, \"times_seen\": 1.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.006114744154709214, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08780196821100254, \"functional effect\": -3.0861, \"times_seen\": 1.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 1.9050471945214111, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.32744614258084875, \"functional effect\": -0.3971, \"times_seen\": 15.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04068685288071237, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08499934259983458, \"functional effect\": -0.0674, \"times_seen\": 13.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.09121514293918684, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08207389340341725, \"functional effect\": -0.0208, \"times_seen\": 42.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0030330523928761978, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08761461758371614, \"functional effect\": -0.4324, \"times_seen\": 8.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03289131046215283, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08944679853963797, \"functional effect\": -0.226, \"times_seen\": 2.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.09477001504537241, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.09336672967362446, \"functional effect\": -1.7952, \"times_seen\": 1.0}, {\"site\": 266, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0018125234190409002, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08732084024262765, \"functional effect\": -2.5755, \"times_seen\": 3.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004425276673060555, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08716284334288782, \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.09232222388119993, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.0820109365157818, \"functional effect\": 0.0225, \"times_seen\": 29.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013565049363922572, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08661239407528798, \"functional effect\": -0.3297, \"times_seen\": 6.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.008666401457333401, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08690698492850019, \"functional effect\": -2.1117, \"times_seen\": 4.0}, {\"site\": 267, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00919845212774687, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08687494046094442, \"functional effect\": -0.1038, \"times_seen\": 1.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.009954550023226696, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08682942235197823, \"functional effect\": -2.8702, \"times_seen\": 2.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.07500551975389333, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.0920963548447186, \"functional effect\": -0.2675, \"times_seen\": 8.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004927222070729644, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08713252274377291, \"functional effect\": 0.1361, \"times_seen\": 1.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.03512606870858042, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08958546046258142, \"functional effect\": 0.0575, \"times_seen\": 48.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05943746154342049, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08390176001722872, \"functional effect\": -0.1649, \"times_seen\": 19.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0293279890293187, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.0856712148792766, \"functional effect\": -0.037, \"times_seen\": 6.0}, {\"site\": 268, \"wildtype\": \"Q\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.010036434189521678, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08804096572521442, \"functional effect\": -0.0978, \"times_seen\": 8.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.008669974133179464, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08690676971316177, \"functional effect\": 0.3883, \"times_seen\": 10.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06433211621025649, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08361758749761891, \"functional effect\": 0.1072, \"times_seen\": 27.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.12140354388957529, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08037434036396539, \"functional effect\": 0.2079, \"times_seen\": 37.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.029602461183334327, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08924312279814038, \"functional effect\": -0.0532, \"times_seen\": 7.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03284299402920004, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08944380298080243, \"functional effect\": -0.0278, \"times_seen\": 5.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.020639032604116855, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08869037636316422, \"functional effect\": -0.0187, \"times_seen\": 20.0}, {\"site\": 269, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.07299342170007905, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08311708822932533, \"functional effect\": 0.0631, \"times_seen\": 40.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015213273716665228, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08651349920344471, \"functional effect\": -2.5379, \"times_seen\": 4.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.002372577804542052, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08757451625746421, \"functional effect\": -0.5758, \"times_seen\": 18.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.41214585343666815, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.11634073265432035, \"functional effect\": -0.2049, \"times_seen\": 34.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.05684336766883214, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.09094421710718581, \"functional effect\": -1.3312, \"times_seen\": 30.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": 1.6550524519809113, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.2753492909090857, \"functional effect\": -1.0518, \"times_seen\": 6.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0721147215030418, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08316772765478378, \"functional effect\": -0.272, \"times_seen\": 37.0}, {\"site\": 270, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.008228570068737319, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08793070928609166, \"functional effect\": -0.7768, \"times_seen\": 18.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.005438582630799802, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08710164425671821, \"functional effect\": 0.0215, \"times_seen\": 5.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0057858356639866925, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.087080681635032, \"functional effect\": -0.5077, \"times_seen\": 1.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.11483149050136718, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08074131287501661, \"functional effect\": -0.1285, \"times_seen\": 48.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.003949153561489325, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08767026991505819, \"functional effect\": -0.8816, \"times_seen\": 2.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.11331716063441465, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.09457479189594702, \"functional effect\": -0.1565, \"times_seen\": 10.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.013057366481725658, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08822551231541202, \"functional effect\": -0.5376, \"times_seen\": 5.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01853053281095616, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08856084999168928, \"functional effect\": -0.0026, \"times_seen\": 2.0}, {\"site\": 271, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.05844312850933693, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.08395960664825057, \"functional effect\": -2.604, \"times_seen\": 3.0}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.020384003039793815, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.08867469968282973, \"functional effect\": -0.4407, \"times_seen\": 17.0}, {\"site\": 272, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.13681532214066738, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.07952030078921643, \"functional effect\": 0.1596, \"times_seen\": 22.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.016173984870274973, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.08841630971924251, \"functional effect\": -0.8345, \"times_seen\": 5.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 2.363863633843519, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.45004650088595344, \"functional effect\": -0.0186, \"times_seen\": 8.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.05071013948509348, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.0905584129911975, \"functional effect\": -3.0628, \"times_seen\": 1.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03520373337488935, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.08959028325047087, \"functional effect\": -0.9047, \"times_seen\": 8.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.005692048730513882, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.0877762468681449, \"functional effect\": -2.8821, \"times_seen\": 2.0}, {\"site\": 273, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011271295826222324, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.08675020941048171, \"functional effect\": -0.9254, \"times_seen\": 7.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.006514339125070664, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.08782629080396849, \"functional effect\": 0.1495, \"times_seen\": 13.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05617472931916601, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.09090207743086813, \"functional effect\": 0.2832, \"times_seen\": 10.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0010683983646938109, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.08736589091749387, \"functional effect\": 0.0198, \"times_seen\": 10.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.3246380679329126, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.0698132303390086, \"functional effect\": -2.5621, \"times_seen\": 3.0}, {\"site\": 274, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.006065891757066345, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.0870637791657686, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.023579888776084527, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08601323384021536, \"functional effect\": -0.2369, \"times_seen\": 6.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.018846434039063015, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08858024393403667, \"functional effect\": -1.1404, \"times_seen\": 2.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.026773845094218297, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08906831993269994, \"functional effect\": -0.0428, \"times_seen\": 8.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.040947895110330076, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08994770246797384, \"functional effect\": -0.1839, \"times_seen\": 13.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -2.6685641832610415e-05, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08742899713388137, \"functional effect\": -0.1017, \"times_seen\": 7.0}, {\"site\": 275, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0178381130482794, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08635623964693727, \"functional effect\": -2.2104, \"times_seen\": 1.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.008345523855835986, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.08692631653047486, \"functional effect\": -2.0079, \"times_seen\": 2.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.009710779427485747, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.08684409506364085, \"functional effect\": -1.7772, \"times_seen\": 2.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.027804070340694823, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.085761757190121, \"functional effect\": 0.0871, \"times_seen\": 41.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.026172773185608383, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.08585878534403664, \"functional effect\": -0.6036, \"times_seen\": 9.0}, {\"site\": 276, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.07609360122538719, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.09216584017082952, \"functional effect\": -0.0587, \"times_seen\": 13.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.008773612691323412, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.0879639353229668, \"functional effect\": -2.2279, \"times_seen\": 4.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03096902583512483, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08932769664934793, \"functional effect\": -0.5216, \"times_seen\": 1.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005619711438206673, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08709070942560485, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.003994332419216746, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08718888345258602, \"functional effect\": -2.205, \"times_seen\": 1.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.17398400093330754, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.09863656349694042, \"functional effect\": -0.4854, \"times_seen\": 23.0}, {\"site\": 277, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01155557685116619, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08673311708801913, \"functional effect\": -0.5363, \"times_seen\": 7.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.007865413444754204, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08790857806646052, \"functional effect\": -0.0399, \"times_seen\": 6.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.008192969181027045, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08792853947709175, \"functional effect\": -0.022, \"times_seen\": 12.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.2161593459241728, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.07526500295109918, \"functional effect\": -0.0907, \"times_seen\": 20.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.11306482126117536, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08084024616527415, \"functional effect\": -0.0742, \"times_seen\": 66.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0042228418381902244, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08768690309150337, \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0855839596566387, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08239487343322745, \"functional effect\": 0.0644, \"times_seen\": 35.0}, {\"site\": 278, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.014456957966751846, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08655886476859849, \"functional effect\": 0.1804, \"times_seen\": 3.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0038186851218457696, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08719949929558007, \"functional effect\": -0.3515, \"times_seen\": 3.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.007978423427578877, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08791546443934266, \"functional effect\": 0.3023, \"times_seen\": 5.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.001668500501077098, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08732955783685968, \"functional effect\": -0.158, \"times_seen\": 6.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.005658858834499094, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08777422755643102, \"functional effect\": -0.1816, \"times_seen\": 10.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.022069911224767154, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08877838395553828, \"functional effect\": -0.5737, \"times_seen\": 7.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.08061560862276962, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08267911392826235, \"functional effect\": -0.5124, \"times_seen\": 18.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.00621861100360055, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08780828974244259, \"functional effect\": -0.5122, \"times_seen\": 4.0}, {\"site\": 279, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008388549773183776, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.0879404604174547, \"functional effect\": -0.3142, \"times_seen\": 6.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.009110006950947139, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.0868802665380302, \"functional effect\": -2.6094, \"times_seen\": 3.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.009021809488223821, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.08688557802318789, \"functional effect\": -2.9367, \"times_seen\": 3.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.017128250661200772, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.08639874074967009, \"functional effect\": -2.1027, \"times_seen\": 1.0}, {\"site\": 280, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.006434437773769884, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.08704154098650636, \"functional effect\": -1.1641, \"times_seen\": 11.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.13442099408176977, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.09596840596375014, \"functional effect\": -0.3641, \"times_seen\": 9.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03352016383137909, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08948579581898533, \"functional effect\": 0.0723, \"times_seen\": 35.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01156273573730985, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08673268670533119, \"functional effect\": 0.0307, \"times_seen\": 10.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.036085347840248146, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08527088253474054, \"functional effect\": -0.7634, \"times_seen\": 15.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0037813222390159465, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08720175761544058, \"functional effect\": -2.1294, \"times_seen\": 1.0}, {\"site\": 281, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.001274890006716461, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.0873533872110453, \"functional effect\": -2.5283, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.003999010361615475, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08718860074286443, \"functional effect\": -0.9999, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.01533106969942117, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08836466631639002, \"functional effect\": 0.3094, \"times_seen\": 2.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.003616221314204719, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08721173748938961, \"functional effect\": 0.0603, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0005782109528793038, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08739558044649368, \"functional effect\": -2.4581, \"times_seen\": 1.0}, {\"site\": 282, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03804045526112283, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08515540364405928, \"functional effect\": -0.5039, \"times_seen\": 7.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.001404094933008881, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.0873455643640448, \"functional effect\": 0.1206, \"times_seen\": 10.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.12109586755192646, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08039148322445613, \"functional effect\": -0.2387, \"times_seen\": 42.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.00517539881920583, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.0871175352337731, \"functional effect\": -0.5709, \"times_seen\": 2.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0171679238205602, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08639636487411524, \"functional effect\": 0.375, \"times_seen\": 6.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01930016235552328, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08626876923707988, \"functional effect\": 0.0237, \"times_seen\": 5.0}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 283, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.013590246557233364, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08825810569098846, \"functional effect\": -0.7594, \"times_seen\": 5.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.026255690280443153, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08585385085943215, \"functional effect\": 0.0436, \"times_seen\": 17.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.019489633147269297, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08625744020477352, \"functional effect\": 0.0117, \"times_seen\": 19.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0029860120270141523, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08724984232200864, \"functional effect\": -0.256, \"times_seen\": 37.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.7863185651595503, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.05069417453162588, \"functional effect\": -0.5928, \"times_seen\": 21.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.2679201697667346, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.10527264565011006, \"functional effect\": -0.2422, \"times_seen\": 42.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.003936858990663156, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.0876695227968388, \"functional effect\": -0.1861, \"times_seen\": 5.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.024008626500566226, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08889776587764475, \"functional effect\": -0.6825, \"times_seen\": 2.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011313561468668366, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08674766798660388, \"functional effect\": -2.4039, \"times_seen\": 2.0}, {\"site\": 284, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04075097260286908, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08993542577899753, \"functional effect\": -1.7855, \"times_seen\": 7.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0299051412384386, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08926184813256942, \"functional effect\": -0.3032, \"times_seen\": 10.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0005593871219050817, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08739672076396905, \"functional effect\": -1.3855, \"times_seen\": 1.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0017109950132854755, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08732698558686716, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.006581683798567634, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08703265770451384, \"functional effect\": -2.0516, \"times_seen\": 1.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00900229209594239, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08688675345620213, \"functional effect\": -0.4047, \"times_seen\": 30.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.19727970758320804, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.07625642136830398, \"functional effect\": -0.6318, \"times_seen\": 42.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.030380395579887393, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08560874286114215, \"functional effect\": 0.0028, \"times_seen\": 20.0}, {\"site\": 285, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03043562876667944, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08929467627903645, \"functional effect\": -2.377, \"times_seen\": 1.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.02802928679171373, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08574837012597553, \"functional effect\": -0.9491, \"times_seen\": 11.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.027453672655922166, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08911030064639948, \"functional effect\": -0.7449, \"times_seen\": 5.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.009936508008018331, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08803486790647791, \"functional effect\": 0.0764, \"times_seen\": 46.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.11086219531141883, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.0944139953332714, \"functional effect\": -0.3648, \"times_seen\": 35.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013807988560166297, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08659781041534319, \"functional effect\": -2.4112, \"times_seen\": 4.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.023932363135649642, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08599222194551485, \"functional effect\": -1.5933, \"times_seen\": 3.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005585954676242619, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08709274723308237, \"functional effect\": -2.7813, \"times_seen\": 1.0}, {\"site\": 286, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0031014574429092338, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08724286081098165, \"functional effect\": -2.8712, \"times_seen\": 1.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.003799023230911409, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08720068770940233, \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02442542329456175, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08596283798495949, \"functional effect\": -2.6977, \"times_seen\": 5.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00020165675053969247, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08741839432419762, \"functional effect\": -2.4834, \"times_seen\": 1.0}, {\"site\": 287, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0017830061552034887, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08753873537369378, \"functional effect\": -1.8107, \"times_seen\": 1.0}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07372547146241373, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.08307492380203786, \"functional effect\": -2.8773, \"times_seen\": 2.0}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.957480207314898, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.022511439742423648, \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 288, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.09820892534562786, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.0816769849311874, \"functional effect\": -2.942, \"times_seen\": 4.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.051729942635748136, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.0843512000408425, \"functional effect\": -0.5923, \"times_seen\": 6.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.030280696866833427, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08561465913323463, \"functional effect\": 0.0892, \"times_seen\": 21.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0522662533137822, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08431984896488694, \"functional effect\": -1.2288, \"times_seen\": 4.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02170533195357115, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08612506723956895, \"functional effect\": -0.0029, \"times_seen\": 65.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -3.7052370898968445, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.006703105037885232, \"functional effect\": -0.4092, \"times_seen\": 99.0}, {\"site\": 289, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.07230944421544552, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08315650313941787, \"functional effect\": -1.2201, \"times_seen\": 29.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.006995489195571678, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08785558644318675, \"functional effect\": -0.1435, \"times_seen\": 20.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.07320518305682834, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.09198149963826686, \"functional effect\": -0.566, \"times_seen\": 18.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.014951898837831431, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08652917438303435, \"functional effect\": -2.7275, \"times_seen\": 5.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02358749846866547, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08887182007717702, \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.018829098690488037, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08857917956482744, \"functional effect\": -1.4644, \"times_seen\": 2.0}, {\"site\": 290, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.012574309790675154, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08819597676647946, \"functional effect\": -0.4162, \"times_seen\": 4.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.01001232866713357, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08803949468963163, \"functional effect\": -0.4328, \"times_seen\": 12.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.021314058589921997, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08614842838928483, \"functional effect\": -1.797, \"times_seen\": 6.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0001403423791508528, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08742210967473622, \"functional effect\": -0.8142, \"times_seen\": 5.0}, {\"site\": 291, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.10037787679872626, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08155428379865962, \"functional effect\": -0.7427, \"times_seen\": 15.0}, {\"site\": 292, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 292, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.016343838972203033, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": 0.08644572961972012, \"functional effect\": -2.5027, \"times_seen\": 4.0}, {\"site\": 292, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005386766453450979, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": 0.08710477267621723, \"functional effect\": -1.8602, \"times_seen\": 1.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.007487275250464129, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.08788553977076351, \"functional effect\": -0.0809, \"times_seen\": 7.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0026748493049263567, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.0872686625339301, \"functional effect\": -1.0336, \"times_seen\": 6.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004540606586263585, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.0871558757710294, \"functional effect\": -1.3293, \"times_seen\": 1.0}, {\"site\": 293, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.00323363338143741, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.08723486821486241, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 294, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.008931228849641726, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": 0.08797354601306374, \"functional effect\": -2.9686, \"times_seen\": 4.0}, {\"site\": 294, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.027321417497316532, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.08910213207547125, \"functional effect\": -2.4414, \"times_seen\": 3.0}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.003493660538674731, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.08721914667283467, \"functional effect\": -2.3102, \"times_seen\": 1.0}, {\"site\": 295, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.012812791757596757, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.08821055704015889, \"functional effect\": -2.7989, \"times_seen\": 4.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.13498577442246013, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.07962120809713091, \"functional effect\": -0.5588, \"times_seen\": 44.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -2.135168343484218, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.019902783222818014, \"functional effect\": -0.0909, \"times_seen\": 46.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.006315822466132116, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.08704869765046366, \"functional effect\": -2.6088, \"times_seen\": 1.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.010548499490708232, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.08679368252259521, \"functional effect\": -2.7361, \"times_seen\": 2.0}, {\"site\": 296, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 297, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 297, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.02334885975909186, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": 0.08602700885397135, \"functional effect\": -0.957, \"times_seen\": 8.0}, {\"site\": 297, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.7702392899562913, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": 0.051262336821114085, \"functional effect\": -0.3747, \"times_seen\": 19.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.47026247825822054, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.06311032521783662, \"functional effect\": -1.8786, \"times_seen\": 2.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006667466118052564, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.08702748291629986, \"functional effect\": -1.2026, \"times_seen\": 1.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.013673505763618622, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.08660588312523776, \"functional effect\": -2.9714, \"times_seen\": 1.0}, {\"site\": 298, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03808294778550444, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.08515289555005803, \"functional effect\": -1.9379, \"times_seen\": 4.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.019842760340641894, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08864143864655147, \"functional effect\": -1.499, \"times_seen\": 2.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.016510344598112167, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08643575324263962, \"functional effect\": -1.3649, \"times_seen\": 2.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.00015000352152901706, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08742152424635623, \"functional effect\": -2.7225, \"times_seen\": 1.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03833338062704723, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08513811541272866, \"functional effect\": -0.1582, \"times_seen\": 10.0}, {\"site\": 299, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.00019850088302804405, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08744264476423279, \"functional effect\": -1.4017, \"times_seen\": 8.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.09604945904267552, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08179933287157276, \"functional effect\": -0.2625, \"times_seen\": 11.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 1.1947228257041898, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.20012942012393978, \"functional effect\": -0.3669, \"times_seen\": 11.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.026544475464932684, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08905416036119367, \"functional effect\": -2.7576, \"times_seen\": 6.0}, {\"site\": 300, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0016300550346525539, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08733188505794513, \"functional effect\": -0.479, \"times_seen\": 3.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.023488846726560646, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08601866192304808, \"functional effect\": 0.4159, \"times_seen\": 7.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.021575446520000343, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08613282140448367, \"functional effect\": 0.2879, \"times_seen\": 6.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03976099669772275, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08987373334815435, \"functional effect\": 0.0628, \"times_seen\": 6.0}, {\"site\": 301, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005005241864289859, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08712781081406452, \"functional effect\": 0.158, \"times_seen\": 1.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01631713683674023, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08644732961617027, \"functional effect\": -0.1786, \"times_seen\": 3.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.01179027597767977, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08814805961146088, \"functional effect\": -1.4452, \"times_seen\": 1.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.005324057579773091, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08710855889627457, \"functional effect\": -2.3834, \"times_seen\": 1.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.012927157998426251, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.0866506984382131, \"functional effect\": -1.1237, \"times_seen\": 4.0}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 302, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02646867584135718, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.0858411771616837, \"functional effect\": -0.0342, \"times_seen\": 6.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.011548419059849449, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.08813328349419206, \"functional effect\": -0.6279, \"times_seen\": 1.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.504414267620262, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.06163390791527465, \"functional effect\": 0.0613, \"times_seen\": 24.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.9204008043069833, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.3309495354082293, \"functional effect\": -1.6708, \"times_seen\": 9.0}, {\"site\": 303, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.02057324019853761, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.08868633183539039, \"functional effect\": -0.909, \"times_seen\": 4.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05552754306422471, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.09086130832873342, \"functional effect\": -0.3108, \"times_seen\": 39.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.024503463934835983, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.0859581880670745, \"functional effect\": -1.2485, \"times_seen\": 14.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.3355029088058691, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.0692894462887216, \"functional effect\": -0.0379, \"times_seen\": 21.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.048748516456196815, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08452569770341041, \"functional effect\": -0.1194, \"times_seen\": 21.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.006872911533183044, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08701509074480056, \"functional effect\": -0.0637, \"times_seen\": 20.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.031183384088558492, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08556110721563193, \"functional effect\": -0.2287, \"times_seen\": 20.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.26535689505758125, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.10508577099811348, \"functional effect\": -0.1652, \"times_seen\": 56.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04680113900987242, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08463986914998423, \"functional effect\": -0.1408, \"times_seen\": 65.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.024259793508083275, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08597270758555509, \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05893068552603968, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08393123739627596, \"functional effect\": -0.5884, \"times_seen\": 31.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.04053104548536402, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08992171690021356, \"functional effect\": -0.2332, \"times_seen\": 14.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.011107723013376505, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08810636577635839, \"functional effect\": -0.3637, \"times_seen\": 43.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.009297704967462142, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08799589605787941, \"functional effect\": -2.9172, \"times_seen\": 5.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03298255898666754, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.0854544710634904, \"functional effect\": -0.1465, \"times_seen\": 13.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02370275040129593, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08600590916283551, \"functional effect\": -0.4913, \"times_seen\": 48.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.5526540521844032, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.05960711234530682, \"functional effect\": -0.1091, \"times_seen\": 45.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.1063110864188608, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.09411662733190343, \"functional effect\": -0.151, \"times_seen\": 28.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.011615287877000287, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08813736856056614, \"functional effect\": -0.1403, \"times_seen\": 7.0}, {\"site\": 304, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02306222358807377, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08883946837700973, \"functional effect\": -0.1142, \"times_seen\": 29.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.009987440362911767, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08682744285072432, \"functional effect\": -3.0197, \"times_seen\": 1.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.006465932654898346, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08703964083922204, \"functional effect\": -2.9654, \"times_seen\": 1.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03994567877576153, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08504302161402537, \"functional effect\": -0.2195, \"times_seen\": 20.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.6031389951736615, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.05755732488584154, \"functional effect\": -0.2644, \"times_seen\": 38.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.025630172612305692, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08589108308310604, \"functional effect\": -1.6965, \"times_seen\": 6.0}, {\"site\": 305, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.009907105969471275, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.0868322778463153, \"functional effect\": 0.0088, \"times_seen\": 6.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.9559065550769463, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.045072016002210925, \"functional effect\": 0.2651, \"times_seen\": 15.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.02682409151775467, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.08907142207302443, \"functional effect\": -0.2689, \"times_seen\": 12.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.1555255321712194, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.09738260330173287, \"functional effect\": -0.3164, \"times_seen\": 43.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014854146227293691, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.08653503753429627, \"functional effect\": -0.3346, \"times_seen\": 10.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.023972990546619114, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.0859898003719662, \"functional effect\": -0.4373, \"times_seen\": 5.0}, {\"site\": 306, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.008195108963257834, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.08693537991103306, \"functional effect\": -0.4553, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.011311376921989892, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.08811880393672192, \"functional effect\": -1.2932, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.012239361058399892, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.08817550279188749, \"functional effect\": -3.1432, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0063840340948355286, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.08781835864204499, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 1.2704650820514538, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.21091702070485496, \"functional effect\": -0.8163, \"times_seen\": 50.0}, {\"site\": 307, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0013996671069258534, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.0873458324397993, \"functional effect\": -2.4752, \"times_seen\": 4.0}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0007996074096640847, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.08738216972092824, \"functional effect\": -2.7756, \"times_seen\": 1.0}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005754052136825974, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.08708260010124917, \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 308, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00553601532157224, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.08709576202882788, \"functional effect\": -2.9695, \"times_seen\": 2.0}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005015047235472623, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.08712721864621342, \"functional effect\": -1.3805, \"times_seen\": 1.0}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.017544517755897788, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.0885003434429561, \"functional effect\": -0.8374, \"times_seen\": 2.0}, {\"site\": 309, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.060620489874444315, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.0838329877050251, \"functional effect\": -0.7195, \"times_seen\": 30.0}, {\"site\": 310, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.04166731366989373, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": 0.0899925672395607, \"functional effect\": -1.1574, \"times_seen\": 18.0}, {\"site\": 310, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0025100326285008878, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": 0.08727863286870657, \"functional effect\": -1.9558, \"times_seen\": 1.0}, {\"site\": 310, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.04848246932333701, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.09041868934922323, \"functional effect\": 0.176, \"times_seen\": 23.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.614340597634034, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.26768773504012405, \"functional effect\": -0.7858, \"times_seen\": 67.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03802717554136625, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.08515618748615252, \"functional effect\": -1.0693, \"times_seen\": 16.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.002783505751425033, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.08726209015000802, \"functional effect\": -2.9646, \"times_seen\": 1.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.014163262305871456, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.08657648772430132, \"functional effect\": -0.3635, \"times_seen\": 15.0}, {\"site\": 311, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.9341816476739759, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.04575587160067444, \"functional effect\": -0.4081, \"times_seen\": 6.0}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.030051082738660646, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.08927087822318538, \"functional effect\": -0.6353, \"times_seen\": 53.0}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.01805144687178365, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.08853144584677725, \"functional effect\": -0.189, \"times_seen\": 6.0}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.025554665913935477, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.08589557850426918, \"functional effect\": -1.8127, \"times_seen\": 2.0}, {\"site\": 312, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.9695342762942917, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.1712073593721445, \"functional effect\": -0.3363, \"times_seen\": 6.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009918663676124668, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08683158221907113, \"functional effect\": -1.5098, \"times_seen\": 17.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.008643857394694194, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.0869083429783752, \"functional effect\": -0.2965, \"times_seen\": 1.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03558130505632811, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08530067932532562, \"functional effect\": -2.2771, \"times_seen\": 1.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.12152733455435197, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08036744412748317, \"functional effect\": -0.6941, \"times_seen\": 34.0}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 313, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.43915702585403116, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.0644858000568659, \"functional effect\": -0.7144, \"times_seen\": 14.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.029704176935289487, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.08564887871499095, \"functional effect\": -0.6442, \"times_seen\": 6.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.016558269354776584, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.08843986392896572, \"functional effect\": -0.6906, \"times_seen\": 15.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.11825023864664139, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.09489872963947645, \"functional effect\": 0.397, \"times_seen\": 5.0}, {\"site\": 314, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0033142980679745308, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.08722999083164412, \"functional effect\": -1.267, \"times_seen\": 13.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.003869435700313211, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08719643187864937, \"functional effect\": -3.0955, \"times_seen\": 1.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02184541248729622, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08876457016681742, \"functional effect\": -2.3483, \"times_seen\": 3.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.024668819959692206, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08594833644261368, \"functional effect\": -2.7033, \"times_seen\": 2.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.010545026529754357, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08807200822071704, \"functional effect\": -1.9318, \"times_seen\": 5.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0040734988035056605, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08718409918489313, \"functional effect\": -3.0863, \"times_seen\": 1.0}, {\"site\": 315, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.001439790788323167, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08751791249372386, \"functional effect\": -0.6018, \"times_seen\": 6.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -1.2813647650954343, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.03596949166830931, \"functional effect\": -2.9537, \"times_seen\": 2.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.023098189962608342, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.08604195743680773, \"functional effect\": -2.6552, \"times_seen\": 3.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014058527632337257, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.08658277310621869, \"functional effect\": -2.9195, \"times_seen\": 3.0}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 316, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.007174134158152227, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.08786646603262155, \"functional effect\": -2.8689, \"times_seen\": 2.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.038623937052964685, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.08512097046181998, \"functional effect\": -0.7064, \"times_seen\": 10.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.06507225095097639, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.09146442940076473, \"functional effect\": -0.8559, \"times_seen\": 34.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.6558806143754337, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.1377536986793301, \"functional effect\": -0.9803, \"times_seen\": 40.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.003998385530637584, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.08767326171411967, \"functional effect\": -1.5735, \"times_seen\": 1.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.002294134539001949, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.08756975472153199, \"functional effect\": -0.7449, \"times_seen\": 1.0}, {\"site\": 317, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0057546141864606645, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08708256617534477, \"functional effect\": -2.6762, \"times_seen\": 1.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.013672512615753914, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08826313853112161, \"functional effect\": -0.9377, \"times_seen\": 1.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.028772340959354773, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08570421715077917, \"functional effect\": -0.5327, \"times_seen\": 10.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.010395394785845122, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08806287414565572, \"functional effect\": -0.8911, \"times_seen\": 9.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.055002680602684664, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08416006713686137, \"functional effect\": -0.0811, \"times_seen\": 12.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.022656365048735097, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.0860683117951893, \"functional effect\": -0.9701, \"times_seen\": 6.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0028979794094379212, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.0876064150090398, \"functional effect\": -1.0749, \"times_seen\": 5.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.003575148121585271, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08764754514845116, \"functional effect\": -0.2258, \"times_seen\": 8.0}, {\"site\": 318, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.010503310970395849, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08679640114253871, \"functional effect\": -0.4794, \"times_seen\": 2.0}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.047332011295070635, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.09034661490569997, \"functional effect\": -0.2729, \"times_seen\": 4.0}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.030108397756873975, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.08927442482416642, \"functional effect\": -1.9086, \"times_seen\": 5.0}, {\"site\": 319, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.018520669411852674, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.08631539313529574, \"functional effect\": -2.2576, \"times_seen\": 4.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.11450526300602369, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08075957246127749, \"functional effect\": -0.3162, \"times_seen\": 10.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0005864813374363905, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.0874661636634601, \"functional effect\": -0.7671, \"times_seen\": 3.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.1500004234001133, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.19402073810981424, \"functional effect\": -0.4383, \"times_seen\": 60.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.037904342898720855, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08516343808627862, \"functional effect\": -0.5786, \"times_seen\": 14.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.037638626469074676, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08974161596006293, \"functional effect\": -0.137, \"times_seen\": 12.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.012505973687530102, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08667599917159928, \"functional effect\": -0.6717, \"times_seen\": 5.0}, {\"site\": 320, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0207449252035814, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08618242006295765, \"functional effect\": -0.1638, \"times_seen\": 5.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.06299114017571382, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.09133258560811545, \"functional effect\": 0.0029, \"times_seen\": 15.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.023813588941837015, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08599930180438506, \"functional effect\": -0.3656, \"times_seen\": 7.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.007512743659296686, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08697650829675688, \"functional effect\": -0.5403, \"times_seen\": 58.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.022231617947574684, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08609365509150782, \"functional effect\": -0.5867, \"times_seen\": 7.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.2925276900213304, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.10708364341859042, \"functional effect\": -0.0984, \"times_seen\": 34.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.021408412963579072, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08873768700750366, \"functional effect\": -0.1734, \"times_seen\": 2.0}, {\"site\": 321, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0002940565041354302, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08741279565004574, \"functional effect\": -0.7978, \"times_seen\": 10.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.009033077466375055, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08688489941756174, \"functional effect\": -0.6202, \"times_seen\": 6.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0019401472467148217, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08754827077876876, \"functional effect\": -1.2264, \"times_seen\": 15.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.02045001272802438, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08620003908019644, \"functional effect\": -0.7689, \"times_seen\": 2.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.014027988299582973, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08658460593161163, \"functional effect\": -2.213, \"times_seen\": 3.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.007591923205039407, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08697173488918133, \"functional effect\": -1.5172, \"times_seen\": 2.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07357019221703959, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08308386575120173, \"functional effect\": -0.3715, \"times_seen\": 21.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.01342339604427193, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08824789905806688, \"functional effect\": -0.9655, \"times_seen\": 12.0}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 322, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.067171983836569, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.0834531526657089, \"functional effect\": -0.9614, \"times_seen\": 8.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.036704778384575955, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.08968354553188132, \"functional effect\": -1.4178, \"times_seen\": 1.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.007680734012495202, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.08789732560716951, \"functional effect\": -1.7148, \"times_seen\": 1.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.03492914946830561, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.08533924734443861, \"functional effect\": -1.0998, \"times_seen\": 1.0}, {\"site\": 323, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.9112673207395374, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.16443048113633904, \"functional effect\": -0.3931, \"times_seen\": 9.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0019506527791770109, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08754890829711001, \"functional effect\": -0.7275, \"times_seen\": 3.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005172592030937847, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08711770472261637, \"functional effect\": -2.6838, \"times_seen\": 2.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.006990378883876298, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08700800607633205, \"functional effect\": -1.3291, \"times_seen\": 3.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.6205783757101542, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.05686575691370344, \"functional effect\": -0.1757, \"times_seen\": 21.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0019619828001591322, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08754959585396359, \"functional effect\": -0.3755, \"times_seen\": 11.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.04207777241994292, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.09001817451672747, \"functional effect\": -0.9679, \"times_seen\": 6.0}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 324, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.019140884314913755, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08627829410455191, \"functional effect\": -0.8286, \"times_seen\": 4.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.02023273129949877, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08621302247418423, \"functional effect\": -2.836, \"times_seen\": 2.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.013720760977382337, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08660304641174033, \"functional effect\": -2.8843, \"times_seen\": 2.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.012508947046927026, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08667582053465679, \"functional effect\": -2.1289, \"times_seen\": 3.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.003943624950928938, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08719194799853276, \"functional effect\": -2.6076, \"times_seen\": 5.0}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 325, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005879323834951105, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08707503889720163, \"functional effect\": -2.5307, \"times_seen\": 1.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02752406876525235, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08911464887754812, \"functional effect\": -1.4592, \"times_seen\": 4.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.014182032906662645, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08829431615431596, \"functional effect\": -0.6351, \"times_seen\": 3.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0007453455525992861, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08738545635312552, \"functional effect\": -0.4705, \"times_seen\": 1.0}, {\"site\": 326, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005295640759599371, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08711027469383557, \"functional effect\": -0.0063, \"times_seen\": 2.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.011778190179555609, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08814732117737674, \"functional effect\": -0.7972, \"times_seen\": 3.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.009942664332112482, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08683013770201109, \"functional effect\": -2.3054, \"times_seen\": 2.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.047836407959403575, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08457915389563513, \"functional effect\": -2.0515, \"times_seen\": 13.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01785005300835151, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08635552495273134, \"functional effect\": -0.7268, \"times_seen\": 9.0}, {\"site\": 327, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0411178291878564, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.0849739545374609, \"functional effect\": -0.5332, \"times_seen\": 8.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.04242519890337107, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08489698605078186, \"functional effect\": -0.6479, \"times_seen\": 7.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.05109027162408788, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08438860848795068, \"functional effect\": -0.8157, \"times_seen\": 6.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.030146948968648467, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08562259657752354, \"functional effect\": -0.4035, \"times_seen\": 4.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04338704298037548, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08484040413543512, \"functional effect\": -0.5622, \"times_seen\": 9.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -5.097733854583989e-05, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08742752504120603, \"functional effect\": -0.3715, \"times_seen\": 2.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03864321012633483, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08511983333186213, \"functional effect\": -0.8968, \"times_seen\": 10.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.009957274449451225, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08682925838098973, \"functional effect\": -1.143, \"times_seen\": 2.0}, {\"site\": 328, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.003347079857118279, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08722800876156182, \"functional effect\": -0.7836, \"times_seen\": 6.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0014643240868341845, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08751940076481889, \"functional effect\": -1.0754, \"times_seen\": 2.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0035819029443557747, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08721381207908156, \"functional effect\": -0.7585, \"times_seen\": 8.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01180603569188348, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08814902252862311, \"functional effect\": -0.3776, \"times_seen\": 8.0}, {\"site\": 329, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02317884664082672, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08603714722793612, \"functional effect\": 0.2852, \"times_seen\": 11.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.38977927565360426, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.11455097330815642, \"functional effect\": -0.7535, \"times_seen\": 12.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.018817549490373998, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08857847046515845, \"functional effect\": -1.5184, \"times_seen\": 2.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0660934592371306, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08351556358912891, \"functional effect\": -1.1133, \"times_seen\": 19.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.03826874372848635, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08514192993128734, \"functional effect\": -0.5261, \"times_seen\": 6.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01013309235367847, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08681867734507097, \"functional effect\": -1.2929, \"times_seen\": 3.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02528533886212378, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08591161527002128, \"functional effect\": -0.6052, \"times_seen\": 3.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.02527047104175477, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08591250064427504, \"functional effect\": -0.9414, \"times_seen\": 13.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.002776081715740953, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.0872625391974641, \"functional effect\": 0.1851, \"times_seen\": 1.0}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 330, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.035351581578257914, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08531426301999866, \"functional effect\": -1.0236, \"times_seen\": 9.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02313145521182274, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08603997352885893, \"functional effect\": 0.1305, \"times_seen\": 5.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.006958128627900956, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08700995109017892, \"functional effect\": -0.3008, \"times_seen\": 10.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.08320179886154, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08253103524613799, \"functional effect\": -0.0467, \"times_seen\": 13.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.017806860984051025, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08635811034025975, \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03654518760662178, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08524370791136279, \"functional effect\": 0.1552, \"times_seen\": 9.0}, {\"site\": 331, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.1300726368753348, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.07989282253870175, \"functional effect\": -0.6434, \"times_seen\": 15.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.043378334430901895, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08484091625966494, \"functional effect\": 0.1562, \"times_seen\": 6.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.020473107500315068, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08868017662359724, \"functional effect\": -0.5329, \"times_seen\": 11.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.013987717067151103, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08828242463996216, \"functional effect\": -0.1499, \"times_seen\": 2.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.05519435861633704, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08414888628265811, \"functional effect\": 0.3107, \"times_seen\": 44.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004553436223519759, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08715510071235981, \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0004893270679877978, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08746027369720219, \"functional effect\": 0.1127, \"times_seen\": 3.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03147660479269864, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08935913006726748, \"functional effect\": -0.1485, \"times_seen\": 4.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0039546972131550544, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08719127882841693, \"functional effect\": -0.1033, \"times_seen\": 5.0}, {\"site\": 332, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.052940674459398804, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08428044091420467, \"functional effect\": 0.1043, \"times_seen\": 10.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.002662416962123778, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08726941456992703, \"functional effect\": -3.0902, \"times_seen\": 1.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00513602932731192, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08711991260376309, \"functional effect\": -0.5053, \"times_seen\": 1.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004043702763792264, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08718589982025533, \"functional effect\": -3.0351, \"times_seen\": 1.0}, {\"site\": 333, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00306162597473404, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08724526953847206, \"functional effect\": -3.0805, \"times_seen\": 1.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.020620570876159892, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08868924142675844, \"functional effect\": -0.5521, \"times_seen\": 7.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.05923448802410521, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.09109507288050281, \"functional effect\": -1.2878, \"times_seen\": 24.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.030548093617844822, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08559879232867035, \"functional effect\": -0.5949, \"times_seen\": 5.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03595371000177671, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08963686834564484, \"functional effect\": -0.0135, \"times_seen\": 4.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0320833163948525, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08550775207690788, \"functional effect\": -0.2692, \"times_seen\": 29.0}, {\"site\": 334, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06849048474551261, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08337691840316594, \"functional effect\": -0.9523, \"times_seen\": 26.0}, {\"site\": 335, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 335, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.004126090856430416, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": 0.08768102277081564, \"functional effect\": -1.541, \"times_seen\": 1.0}, {\"site\": 335, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.1924478170230476, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": 0.09990704078260462, \"functional effect\": -0.2003, \"times_seen\": 16.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.00794603194366032, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08695039034222954, \"functional effect\": -2.9687, \"times_seen\": 2.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.4374148421509538, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.11839640564640717, \"functional effect\": -0.0839, \"times_seen\": 90.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.03914924527298077, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08508998220406275, \"functional effect\": -2.0663, \"times_seen\": 14.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.6040120930040003, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.05752250257698234, \"functional effect\": 0.1538, \"times_seen\": 47.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.2055433036373477, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.075820881656277, \"functional effect\": -0.3194, \"times_seen\": 20.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.5767716924566327, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.05861893851660421, \"functional effect\": -0.2671, \"times_seen\": 97.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.005244236304466395, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08774900535619251, \"functional effect\": 0.1039, \"times_seen\": 23.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.5373445882435951, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.12688794650782084, \"functional effect\": 0.0518, \"times_seen\": 28.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.11745936852060385, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.09484672141847958, \"functional effect\": -0.2848, \"times_seen\": 20.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.2704748014795337, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.10545922082819016, \"functional effect\": 0.1498, \"times_seen\": 72.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05991083479765327, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08387423491118139, \"functional effect\": 0.024, \"times_seen\": 19.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.4182211535422507, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.11683168544849513, \"functional effect\": -0.1268, \"times_seen\": 37.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0017611338468791675, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.0873239507132511, \"functional effect\": -0.5614, \"times_seen\": 56.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03215934280053997, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08940142820432978, \"functional effect\": 0.0728, \"times_seen\": 24.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.4627752929141981, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.06343870157780325, \"functional effect\": -0.2837, \"times_seen\": 60.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.2705226095308827, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.10546271559544189, \"functional effect\": -0.143, \"times_seen\": 99.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 1.234566000349857, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.20573345887961061, \"functional effect\": -0.0781, \"times_seen\": 62.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.1264148092503046, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08009564083742196, \"functional effect\": 0.1474, \"times_seen\": 83.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.701771025997698, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.14220591427797608, \"functional effect\": 0.011, \"times_seen\": 32.0}, {\"site\": 336, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.13108122117540313, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.07983698919581186, \"functional effect\": -0.2646, \"times_seen\": 30.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.011744259103089702, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08672177447624975, \"functional effect\": -0.5449, \"times_seen\": 10.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.1583293941345588, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.07834325888010127, \"functional effect\": -0.3, \"times_seen\": 42.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.010766296798241901, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08678058065212593, \"functional effect\": -1.2106, \"times_seen\": 11.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.08917116116642627, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.09300509147062881, \"functional effect\": -0.3866, \"times_seen\": 82.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03967790171825765, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.0850588078217618, \"functional effect\": -0.4231, \"times_seen\": 22.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05494383372039963, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08416350005818654, \"functional effect\": -0.356, \"times_seen\": 13.0}, {\"site\": 337, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01596225536227692, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.0864685969862458, \"functional effect\": -0.9399, \"times_seen\": 10.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.00753441448730509, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08788841142751716, \"functional effect\": -0.1591, \"times_seen\": 9.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.030295210972709978, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08561379781886021, \"functional effect\": 0.2472, \"times_seen\": 25.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01012076364848072, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08681941926655941, \"functional effect\": 0.2113, \"times_seen\": 5.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05861923669702411, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08394935841745357, \"functional effect\": -0.6083, \"times_seen\": 9.0}, {\"site\": 338, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.047232349846923406, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.08461457470181741, \"functional effect\": -0.9156, \"times_seen\": 26.0}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.010976912763051414, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.0867679126653857, \"functional effect\": -2.5995, \"times_seen\": 1.0}, {\"site\": 339, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.021372502302100697, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.08614493857901216, \"functional effect\": -2.1252, \"times_seen\": 4.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.09007903635810713, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08213855115298556, \"functional effect\": -2.1705, \"times_seen\": 5.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0010855081628210108, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08736485479839003, \"functional effect\": -1.0153, \"times_seen\": 6.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02223087894119291, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08609369919214935, \"functional effect\": -1.1804, \"times_seen\": 9.0}, {\"site\": 340, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.014887314844154814, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08833749063572191, \"functional effect\": -1.4042, \"times_seen\": 4.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02869890543057998, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08570857974613695, \"functional effect\": -1.243, \"times_seen\": 8.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01154690001428385, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08673363873074406, \"functional effect\": -0.3353, \"times_seen\": 7.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05916245770448712, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08391775473869031, \"functional effect\": -0.2672, \"times_seen\": 36.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.026984899836890675, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08581046703440456, \"functional effect\": -0.5728, \"times_seen\": 65.0}, {\"site\": 341, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.04878805380628482, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.0845233812912691, \"functional effect\": -0.4456, \"times_seen\": 42.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.02712628563886701, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08580205792029423, \"functional effect\": -0.6463, \"times_seen\": 5.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009506345780339763, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08685640197017822, \"functional effect\": -1.1581, \"times_seen\": 2.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.010911795277677569, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08677182911039821, \"functional effect\": -2.2256, \"times_seen\": 3.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.018441010000661864, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08632015923140714, \"functional effect\": -0.1618, \"times_seen\": 16.0}, {\"site\": 342, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.24245968188834102, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.07390535253778159, \"functional effect\": -0.8701, \"times_seen\": 13.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -2.028331814191357, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.02143259772992348, \"functional effect\": -0.1825, \"times_seen\": 38.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.4265570928024133, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.1175086967718465, \"functional effect\": 0.0144, \"times_seen\": 40.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0027717972353606454, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.08759875304016441, \"functional effect\": -0.433, \"times_seen\": 3.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.8504375534996772, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.04849046143948851, \"functional effect\": -0.0793, \"times_seen\": 21.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -2.531031558554034, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.015126801601633516, \"functional effect\": -0.0179, \"times_seen\": 36.0}, {\"site\": 343, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.012458122053583065, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.0866788741083334, \"functional effect\": -0.0394, \"times_seen\": 46.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.02734953497485899, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08910386865287716, \"functional effect\": -2.9264, \"times_seen\": 1.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.02921602268849519, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08921922144777564, \"functional effect\": -1.2666, \"times_seen\": 11.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.001516805818219346, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08752258456534286, \"functional effect\": -0.8318, \"times_seen\": 1.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01113001134321942, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08675870535612679, \"functional effect\": -2.7247, \"times_seen\": 1.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.007881496943937678, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08790955809715628, \"functional effect\": 0.286, \"times_seen\": 15.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1294871808188877, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.07992525020174893, \"functional effect\": -0.1404, \"times_seen\": 54.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.052430044917065814, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08431027653349818, \"functional effect\": -1.4223, \"times_seen\": 66.0}, {\"site\": 345, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.06855615864898908, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.09168557017037669, \"functional effect\": -2.0791, \"times_seen\": 18.0}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.053147079617440446, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.09071150974135622, \"functional effect\": -2.3199, \"times_seen\": 7.0}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005132034163581186, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.08712015385973688, \"functional effect\": -2.6787, \"times_seen\": 1.0}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.018951733685592546, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.08628960672644044, \"functional effect\": -0.9486, \"times_seen\": 42.0}, {\"site\": 346, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.008907239349146735, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08797208317870206, \"functional effect\": -2.7213, \"times_seen\": 6.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0027437433428605267, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08726449523119156, \"functional effect\": -2.8082, \"times_seen\": 1.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.007925039795486147, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08695165553598544, \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01747181310697336, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08637816826017317, \"functional effect\": -2.448, \"times_seen\": 3.0}, {\"site\": 347, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.011220478809201361, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.08675326512522664, \"functional effect\": -0.2001, \"times_seen\": 8.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -1.0016922690665022, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.04366405954214047, \"functional effect\": -1.3139, \"times_seen\": 36.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.019013063787624324, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.08859047544920574, \"functional effect\": -1.8702, \"times_seen\": 2.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.013496461459911641, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.08825236849375526, \"functional effect\": -1.7304, \"times_seen\": 2.0}, {\"site\": 348, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.02470268904476487, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.0889405437703287, \"functional effect\": -1.6949, \"times_seen\": 5.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.014259823926770724, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.08657069323136722, \"functional effect\": -1.3905, \"times_seen\": 4.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.01650453611867959, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.08643610124501809, \"functional effect\": -0.151, \"times_seen\": 3.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1860148473137661, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.0768541778915511, \"functional effect\": -0.3134, \"times_seen\": 29.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.055536583007078796, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.0841289275351727, \"functional effect\": -1.7921, \"times_seen\": 11.0}, {\"site\": 349, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05289315045297963, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.0842832172529821, \"functional effect\": -2.0636, \"times_seen\": 12.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.017682803332869177, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08636553661169062, \"functional effect\": -2.6704, \"times_seen\": 14.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.02173532467004487, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08612327677256157, \"functional effect\": -1.6642, \"times_seen\": 4.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.005434722441679133, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.0871018773130883, \"functional effect\": -1.2602, \"times_seen\": 3.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.011477147425841385, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08673783230034125, \"functional effect\": -2.2285, \"times_seen\": 4.0}, {\"site\": 350, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.2533743235384623, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.10421657624235522, \"functional effect\": 0.0623, \"times_seen\": 14.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.004188970900776346, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.087177121322201, \"functional effect\": 0.147, \"times_seen\": 2.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.003568868677044238, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08721460003027212, \"functional effect\": -0.4126, \"times_seen\": 1.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.013267125781569048, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08663028180518535, \"functional effect\": -0.0631, \"times_seen\": 23.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.0273502368945842, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.1782078240098414, \"functional effect\": -0.0079, \"times_seen\": 37.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0962887321689534, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.09346506806677507, \"functional effect\": -0.0514, \"times_seen\": 17.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.022590342486436023, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08607225065984357, \"functional effect\": 0.0793, \"times_seen\": 12.0}, {\"site\": 351, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004661045056088286, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08714860016400296, \"functional effect\": -1.1562, \"times_seen\": 9.0}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.2037693280756968, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.07591417033910364, \"functional effect\": -2.9596, \"times_seen\": 2.0}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01458298974006144, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.0865513034403742, \"functional effect\": -2.7349, \"times_seen\": 2.0}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 352, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.008403564409627674, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.08692281949893181, \"functional effect\": -2.9759, \"times_seen\": 1.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0033883380569096596, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.0872255142502125, \"functional effect\": -0.879, \"times_seen\": 8.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03861519192021448, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.08512148643811542, \"functional effect\": 0.0611, \"times_seen\": 16.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.22589385298441686, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.07475886588531794, \"functional effect\": -0.716, \"times_seen\": 43.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009286021622075069, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.0868696674382265, \"functional effect\": 0.1857, \"times_seen\": 6.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.2644182596677423, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.10501742312105958, \"functional effect\": -0.0135, \"times_seen\": 63.0}, {\"site\": 353, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.3609538015330897, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.06807781504768178, \"functional effect\": 0.1867, \"times_seen\": 5.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.07784416200353113, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.0828380948475201, \"functional effect\": -0.5066, \"times_seen\": 8.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -1.0273953853691558, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.04289302756111649, \"functional effect\": -1.2627, \"times_seen\": 12.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03758052907189459, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08518255521990079, \"functional effect\": 0.0912, \"times_seen\": 8.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0414524236228592, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08997916380620101, \"functional effect\": 0.1788, \"times_seen\": 61.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.018027517553549664, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08634490309502346, \"functional effect\": -0.1804, \"times_seen\": 9.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.037783362411147964, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08517057996032594, \"functional effect\": -0.1978, \"times_seen\": 6.0}, {\"site\": 354, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.009478247769471676, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08685809360688804, \"functional effect\": -0.0626, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005176275529910427, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08711748229337313, \"functional effect\": -2.5714, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03427114421645663, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08953238887518626, \"functional effect\": -0.1098, \"times_seen\": 5.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.022414348244394047, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08608275124665436, \"functional effect\": -2.9698, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.004708222522720862, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08714575037050093, \"functional effect\": -2.0747, \"times_seen\": 1.0}, {\"site\": 355, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.022081003103766123, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08610264358799231, \"functional effect\": -1.0623, \"times_seen\": 5.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01472383325084412, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08654285425736748, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07759105443382684, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08285262930394241, \"functional effect\": -1.0958, \"times_seen\": 40.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.14207428113297008, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.07923095847696722, \"functional effect\": -0.7569, \"times_seen\": 17.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005569916948002901, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08709371540552063, \"functional effect\": -1.8765, \"times_seen\": 1.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.20880750455330366, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.07564952540407935, \"functional effect\": -0.2229, \"times_seen\": 57.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.08710894137826723, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08230782503624688, \"functional effect\": -0.2929, \"times_seen\": 38.0}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 356, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.4471451221172364, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.06412973359449517, \"functional effect\": -0.1307, \"times_seen\": 15.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.019957966514600616, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08622944351799099, \"functional effect\": -1.1934, \"times_seen\": 3.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0729690469260467, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08311849252981927, \"functional effect\": 0.1485, \"times_seen\": 20.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.00873728776998054, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08796172054942482, \"functional effect\": -1.5839, \"times_seen\": 9.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014994398143261003, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08652662542047358, \"functional effect\": -2.5769, \"times_seen\": 1.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01426004977713727, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.0865706796789388, \"functional effect\": -0.6761, \"times_seen\": 10.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.007376382083251052, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08698472958673108, \"functional effect\": -2.6163, \"times_seen\": 8.0}, {\"site\": 357, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03416112097709629, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08538469036651901, \"functional effect\": -0.9013, \"times_seen\": 11.0}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.01545948229543378, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.08837253190190081, \"functional effect\": -2.0623, \"times_seen\": 1.0}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.1805817532179576, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.07714415130956111, \"functional effect\": -3.0611, \"times_seen\": 2.0}, {\"site\": 358, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.8105360804238372, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.15334132186673974, \"functional effect\": -2.0774, \"times_seen\": 2.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.005403827227138767, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08710374261374056, \"functional effect\": -1.5445, \"times_seen\": 1.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.032239075903919216, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08549852079367445, \"functional effect\": -2.0064, \"times_seen\": 8.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.006320143119504422, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08704843695317477, \"functional effect\": 0.3073, \"times_seen\": 19.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03515795088147856, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08532571420569715, \"functional effect\": -0.6073, \"times_seen\": 8.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.04655423181184909, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08465435591311335, \"functional effect\": -0.4763, \"times_seen\": 9.0}, {\"site\": 359, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.011730805784393571, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.08672258317183451, \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02174582043466617, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.08612265021855832, \"functional effect\": 0.1011, \"times_seen\": 4.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0388682711788693, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.08510655563660885, \"functional effect\": -0.5295, \"times_seen\": 7.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.14118543424149757, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.07927978784689126, \"functional effect\": -0.8575, \"times_seen\": 30.0}, {\"site\": 360, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.5635312558337997, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.029579697123640388, \"functional effect\": -0.3613, \"times_seen\": 15.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015861468164153666, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.08647463792476016, \"functional effect\": -1.3617, \"times_seen\": 2.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.22719983395944754, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.10234284720560907, \"functional effect\": -2.1651, \"times_seen\": 4.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0379972068416002, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.08515795643014279, \"functional effect\": -0.5487, \"times_seen\": 24.0}, {\"site\": 361, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.012082957206925435, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.08670141739997407, \"functional effect\": -2.0705, \"times_seen\": 3.0}, {\"site\": 362, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.12448405870112329, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": 0.08020290413589297, \"functional effect\": 0.3737, \"times_seen\": 28.0}, {\"site\": 362, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.012670684189385054, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": 0.08666610405725592, \"functional effect\": -2.4808, \"times_seen\": 2.0}, {\"site\": 362, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.11189160542982135, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.09448138684844827, \"functional effect\": -0.4622, \"times_seen\": 7.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0067004003556892676, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.0878376182994306, \"functional effect\": -1.6583, \"times_seen\": 4.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.016466569310071302, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08643837597807101, \"functional effect\": -2.019, \"times_seen\": 4.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004979787527629866, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08712934807601594, \"functional effect\": -1.9635, \"times_seen\": 2.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00048546214343936144, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08740119916449636, \"functional effect\": 0.0449, \"times_seen\": 1.0}, {\"site\": 363, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009875022266615924, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08683420890721132, \"functional effect\": -1.8807, \"times_seen\": 2.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.07853321859332389, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.09232182573739503, \"functional effect\": -0.138, \"times_seen\": 30.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.020654123563161708, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.08869130409203248, \"functional effect\": -0.7208, \"times_seen\": 3.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.712433227288124, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.14326077666422185, \"functional effect\": -0.2354, \"times_seen\": 19.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.005017323174801549, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.08773520490975457, \"functional effect\": -0.2734, \"times_seen\": 25.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03391490174468841, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.08951028350917667, \"functional effect\": -0.1391, \"times_seen\": 13.0}, {\"site\": 364, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.019871622694557146, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.08623460441627244, \"functional effect\": -0.39, \"times_seen\": 13.0}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.5070870188080675, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.12425444476411161, \"functional effect\": 0.0653, \"times_seen\": 99.0}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 365, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.001099486903476535, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.08749727114370365, \"functional effect\": -1.7436, \"times_seen\": 2.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0260449541501098, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.08586639254651961, \"functional effect\": -1.9688, \"times_seen\": 31.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.8500519264809726, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.15759943554825723, \"functional effect\": -0.9627, \"times_seen\": 59.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.05753127074264093, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.09098759129379644, \"functional effect\": 0.1515, \"times_seen\": 192.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -7.850248140181276e-05, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.08742585702953905, \"functional effect\": -0.013, \"times_seen\": 2.0}, {\"site\": 366, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.1548201027075858, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.07853405732807676, \"functional effect\": 0.0556, \"times_seen\": 59.0}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.04984365750668866, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.08446155910592092, \"functional effect\": 0.1043, \"times_seen\": 52.0}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06529668069935446, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.08356170070445222, \"functional effect\": 0.0551, \"times_seen\": 28.0}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 367, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.05347351469238638, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.09073203713484257, \"functional effect\": -0.1012, \"times_seen\": 119.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.03768730790264015, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08517625079880346, \"functional effect\": -2.6155, \"times_seen\": 10.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.13842058822682282, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.07943186889828908, \"functional effect\": -0.4914, \"times_seen\": 69.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.028123001584040956, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08574280025190069, \"functional effect\": -1.1983, \"times_seen\": 29.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.05990873018555573, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.09113765602638828, \"functional effect\": -0.3662, \"times_seen\": 26.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.12555277574352522, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.09538029943157372, \"functional effect\": -0.5704, \"times_seen\": 46.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.5376664716927269, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.12691625996656639, \"functional effect\": 0.3186, \"times_seen\": 59.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.5940323639591708, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.13197300022845126, \"functional effect\": -0.4595, \"times_seen\": 68.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.061529945593909154, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08378015716083963, \"functional effect\": -0.1037, \"times_seen\": 49.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.06694119704296343, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08346650366890127, \"functional effect\": -0.0442, \"times_seen\": 29.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.0874085483519629, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.1857830637508323, \"functional effect\": -0.6695, \"times_seen\": 55.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.2732646209229685, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.1056633504793457, \"functional effect\": 0.0595, \"times_seen\": 69.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.6965670784142849, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.14169388711989606, \"functional effect\": -0.284, \"times_seen\": 25.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.15320794829061765, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.07862186507015036, \"functional effect\": -1.429, \"times_seen\": 156.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05255901100341592, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08430274016571407, \"functional effect\": -0.2541, \"times_seen\": 84.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.321211628238481, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.1092340069927629, \"functional effect\": -0.63, \"times_seen\": 155.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.2980463374952147, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.21498809591807666, \"functional effect\": -0.2365, \"times_seen\": 113.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.21409301174671105, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.07537288027253303, \"functional effect\": -0.5176, \"times_seen\": 84.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.1179040730258845, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.09487596201646398, \"functional effect\": -0.1334, \"times_seen\": 87.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.019901286692773905, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08864503467005957, \"functional effect\": 0.4396, \"times_seen\": 66.0}, {\"site\": 368, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0480570403661392, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08456622013284061, \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.00014930304892545206, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08742156669219255, \"functional effect\": -0.1683, \"times_seen\": 1.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0008489790140498668, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08737917939797528, \"functional effect\": -0.1472, \"times_seen\": 2.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.04641114383289025, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.09028896536161124, \"functional effect\": -0.4262, \"times_seen\": 29.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.006447437722906123, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08782221817212202, \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.2633614208583383, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.07284233226526457, \"functional effect\": -0.3405, \"times_seen\": 66.0}, {\"site\": 369, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0542183014593702, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08420583658096616, \"functional effect\": -0.0329, \"times_seen\": 37.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.021858628250594835, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08611591634343158, \"functional effect\": -2.9613, \"times_seen\": 2.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01794199928272071, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08635002149181166, \"functional effect\": -0.2148, \"times_seen\": 49.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.014907899247897123, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08653181340662561, \"functional effect\": -1.8573, \"times_seen\": 4.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.96284126012894, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.17041492600516184, \"functional effect\": 0.0955, \"times_seen\": 16.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.00041293121106154005, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08745564248584947, \"functional effect\": 0.0605, \"times_seen\": 20.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.5900991732211722, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.05807991584303464, \"functional effect\": -1.1184, \"times_seen\": 17.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.4424942738767765, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.1188139896571641, \"functional effect\": -0.1726, \"times_seen\": 42.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -3.3537270936507975, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.008552460508920416, \"functional effect\": -0.1823, \"times_seen\": 43.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0003406026973749585, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08745125806787155, \"functional effect\": -1.1776, \"times_seen\": 12.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.18378358198042374, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.07697313216327971, \"functional effect\": -0.9567, \"times_seen\": 22.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.39125936401281036, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.06666267323880104, \"functional effect\": -1.0822, \"times_seen\": 61.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.004153338951515372, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08717927446547509, \"functional effect\": -0.4088, \"times_seen\": 13.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.7339450039840996, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.05256831645546231, \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.01962844744850209, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08862827190541403, \"functional effect\": -0.1828, \"times_seen\": 29.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.7960695226641032, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.15181138237610606, \"functional effect\": -0.9029, \"times_seen\": 68.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01877836608434599, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08629997670803605, \"functional effect\": -0.0398, \"times_seen\": 92.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.2382779007498895, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.07411988460927706, \"functional effect\": -0.1946, \"times_seen\": 67.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.045848603070836595, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08469577087295771, \"functional effect\": -0.8733, \"times_seen\": 24.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"W\", \"log2 fold change IC90\": 5.164602140034603e-05, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08743374425263438, \"functional effect\": -1.2685, \"times_seen\": 16.0}, {\"site\": 370, \"wildtype\": \"P\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02033416588743308, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08867163651420218, \"functional effect\": -0.5623, \"times_seen\": 18.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04225396623988101, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.09002916895015817, \"functional effect\": -0.1664, \"times_seen\": 3.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.260265775062887, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.20943117569966485, \"functional effect\": -0.0949, \"times_seen\": 59.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.08161617683448269, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.09251932323704994, \"functional effect\": -0.1855, \"times_seen\": 17.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.027836394305057032, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.08575983569677055, \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 371, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.028755407340994302, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.08919074059643928, \"functional effect\": 0.397, \"times_seen\": 4.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.03232472652968992, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08549344502628951, \"functional effect\": -2.2564, \"times_seen\": 7.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.4497607502691129, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.11941393416233465, \"functional effect\": 0.1646, \"times_seen\": 82.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.4929801764219675, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.062124328800485976, \"functional effect\": -0.0937, \"times_seen\": 58.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.13047497579833572, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.09570627457045822, \"functional effect\": 0.4444, \"times_seen\": 48.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"E\", \"log2 fold change IC90\": 1.0581695771015205, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.1820557135471704, \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.28994265288734306, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.1068919415449339, \"functional effect\": 0.1997, \"times_seen\": 42.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.29022945951924994, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.10691319369066858, \"functional effect\": 0.3194, \"times_seen\": 35.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.21245082298686704, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.07545872445031858, \"functional effect\": 0.0579, \"times_seen\": 84.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.023130937577041693, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08604000439975652, \"functional effect\": -0.7091, \"times_seen\": 25.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08080011163055544, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08266854095935663, \"functional effect\": 0.2194, \"times_seen\": 153.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.027401127695058945, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08578571367064956, \"functional effect\": 0.2135, \"times_seen\": 29.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.06459305198869313, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.09143405404069953, \"functional effect\": 0.3347, \"times_seen\": 46.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"P\", \"log2 fold change IC90\": -1.1188421375490782, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.040258583128804454, \"functional effect\": 0.3061, \"times_seen\": 81.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.00339055763139413, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08763633150462734, \"functional effect\": 0.397, \"times_seen\": 23.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.332809718970563, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.11011569855387952, \"functional effect\": -1.2678, \"times_seen\": 47.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.5333573066160096, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.06040974218506915, \"functional effect\": 0.4444, \"times_seen\": 227.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.3156950836593956, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.10881711802733506, \"functional effect\": 0.4444, \"times_seen\": 106.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.4453292693624674, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.11904769691044016, \"functional effect\": -0.0682, \"times_seen\": 71.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.1659085505036783, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.07793276405724735, \"functional effect\": -0.1565, \"times_seen\": 26.0}, {\"site\": 372, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.5286194130558194, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.060608457373235745, \"functional effect\": -0.3609, \"times_seen\": 99.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006190233484423009, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0870562757129376, \"functional effect\": -3.1261, \"times_seen\": 1.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.017936660562591022, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0885244022281556, \"functional effect\": -0.6319, \"times_seen\": 46.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02498131230803051, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08592972177481906, \"functional effect\": -0.0101, \"times_seen\": 15.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005572645425825928, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08709355069084458, \"functional effect\": 0.1841, \"times_seen\": 3.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.05566189172774088, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0841216206337379, \"functional effect\": -0.9247, \"times_seen\": 10.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.07944982377217956, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.09238050033532867, \"functional effect\": -0.9607, \"times_seen\": 12.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.02957031580096312, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08924113435133406, \"functional effect\": 0.2849, \"times_seen\": 20.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.040079035569092765, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08503516095034268, \"functional effect\": -0.0169, \"times_seen\": 114.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.03951999944012244, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08985872150317235, \"functional effect\": -0.7514, \"times_seen\": 6.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.02942855690137559, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08923236596776257, \"functional effect\": -0.0194, \"times_seen\": 23.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.010002288104857378, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08682654925589328, \"functional effect\": -0.1995, \"times_seen\": 10.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -2.5654648521014614, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.014770039496478562, \"functional effect\": -0.3342, \"times_seen\": 111.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.024510900030672002, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08892872097690868, \"functional effect\": -1.7207, \"times_seen\": 14.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02909248333440665, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08921158184773877, \"functional effect\": 0.3897, \"times_seen\": 6.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.5113164995001794, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0613397393676606, \"functional effect\": -0.1864, \"times_seen\": 24.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.058176115051231506, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08397514729890392, \"functional effect\": -0.1394, \"times_seen\": 128.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.095273265832583, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0409216770367492, \"functional effect\": -0.1724, \"times_seen\": 27.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.008366978517773006, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08692502383810775, \"functional effect\": -0.169, \"times_seen\": 1.0}, {\"site\": 373, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.011037481208200141, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0881020761660471, \"functional effect\": -0.0853, \"times_seen\": 16.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0053334062145324705, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08710799443639913, \"functional effect\": 0.0743, \"times_seen\": 3.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.38328811625314985, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.11403672855629529, \"functional effect\": -0.2708, \"times_seen\": 24.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013943546637083908, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08658967392022812, \"functional effect\": 0.0102, \"times_seen\": 5.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.008126937170700038, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08792451508857442, \"functional effect\": -1.298, \"times_seen\": 3.0}, {\"site\": 374, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0040895464111143495, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08718312941069103, \"functional effect\": -0.9615, \"times_seen\": 3.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.02708784976073982, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08908770789145053, \"functional effect\": -0.0918, \"times_seen\": 7.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.02342904186289837, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08602222777780595, \"functional effect\": -0.7998, \"times_seen\": 3.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.13286872213169854, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.0797381323210954, \"functional effect\": -0.2157, \"times_seen\": 42.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.02260051193759846, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08881104126421407, \"functional effect\": 0.1052, \"times_seen\": 9.0}, {\"site\": 375, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006474920209853786, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08703909861020169, \"functional effect\": -0.2887, \"times_seen\": 1.0}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.006888080569433367, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.08701417584034099, \"functional effect\": -2.9496, \"times_seen\": 1.0}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004648642891586273, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.08714934934237428, \"functional effect\": -2.2311, \"times_seen\": 1.0}, {\"site\": 376, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008744741269507979, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.08690226591870383, \"functional effect\": -2.8537, \"times_seen\": 3.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.08074782559376643, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.08267153708021278, \"functional effect\": -2.5867, \"times_seen\": 3.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.3403306392188416, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.11069124209666291, \"functional effect\": -0.1709, \"times_seen\": 15.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0044383735442700325, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.08716205207701416, \"functional effect\": -1.3363, \"times_seen\": 1.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.027543716495776378, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.08911586251763134, \"functional effect\": -2.6411, \"times_seen\": 1.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.21296689609112773, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.0754317365888529, \"functional effect\": 0.0603, \"times_seen\": 12.0}, {\"site\": 377, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0002460612048227698, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08741570373038066, \"functional effect\": -2.5781, \"times_seen\": 1.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.00998473284790287, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08803781068942644, \"functional effect\": -1.9055, \"times_seen\": 6.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005018200206372656, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08712702823224719, \"functional effect\": -2.6984, \"times_seen\": 1.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.010304919130769042, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08805735163662126, \"functional effect\": -0.2144, \"times_seen\": 34.0}, {\"site\": 378, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.027012244038271894, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.0858088406363174, \"functional effect\": -0.8982, \"times_seen\": 7.0}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0012251581446463134, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.08750489324628563, \"functional effect\": -0.689, \"times_seen\": 1.0}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.09902384334669884, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.09364243044858307, \"functional effect\": -0.319, \"times_seen\": 43.0}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.045650346696323826, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.09024136453434954, \"functional effect\": -0.8253, \"times_seen\": 10.0}, {\"site\": 379, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.011028128819038628, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.08676483243618413, \"functional effect\": -2.9952, \"times_seen\": 2.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.014676799633099218, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.08654567570594908, \"functional effect\": -0.9598, \"times_seen\": 14.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01002879380401793, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.08682495406273909, \"functional effect\": -2.5084, \"times_seen\": 13.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.08666935036425485, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.08233290815646312, \"functional effect\": -2.2382, \"times_seen\": 1.0}, {\"site\": 380, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.012272440624087758, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08669003079257201, \"functional effect\": -2.9398, \"times_seen\": 1.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.04909210613143399, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08450556961108287, \"functional effect\": -0.2093, \"times_seen\": 40.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.016309907320484877, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08644776281509513, \"functional effect\": -2.4684, \"times_seen\": 6.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.012078288372749964, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08670169798262262, \"functional effect\": -1.3467, \"times_seen\": 2.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.014118069211022885, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08657919981562628, \"functional effect\": -0.2733, \"times_seen\": 8.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.06297779325478123, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.09133174065951205, \"functional effect\": 0.1178, \"times_seen\": 16.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0937701517320422, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08192866940644183, \"functional effect\": -0.8031, \"times_seen\": 25.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.09341255060546082, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08194897960019218, \"functional effect\": -0.4325, \"times_seen\": 23.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.9883518599013936, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.17345510494746452, \"functional effect\": -0.1563, \"times_seen\": 11.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.016643935083780485, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08844511555189473, \"functional effect\": -1.0839, \"times_seen\": 7.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.2982576253956228, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.10750979200353722, \"functional effect\": -0.3583, \"times_seen\": 88.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.032132615832879574, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08550483017589593, \"functional effect\": -0.248, \"times_seen\": 11.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.023199679161969595, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08884793313326034, \"functional effect\": -0.6528, \"times_seen\": 14.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.9475225304435082, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.04533470841115815, \"functional effect\": -0.2759, \"times_seen\": 36.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.22643137373086653, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.1022883481857156, \"functional effect\": -0.4712, \"times_seen\": 42.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.3398413073611755, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.03454069779750436, \"functional effect\": -0.3294, \"times_seen\": 58.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05300417548418238, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08427673134535331, \"functional effect\": -0.6163, \"times_seen\": 48.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.063939990693441, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.09139267417367578, \"functional effect\": -0.2727, \"times_seen\": 19.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.017081678665281513, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.0884719557050843, \"functional effect\": -0.1322, \"times_seen\": 9.0}, {\"site\": 381, \"wildtype\": \"P\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027610870803875563, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08577324280612396, \"functional effect\": -0.1029, \"times_seen\": 7.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.016555661849174542, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.08843970408421288, \"functional effect\": -0.0781, \"times_seen\": 5.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.21689524321171427, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.07522662118209834, \"functional effect\": -0.506, \"times_seen\": 41.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.004257767510546092, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.08768902589710714, \"functional effect\": -0.3039, \"times_seen\": 15.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.00790941618744086, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.08695259718054815, \"functional effect\": 0.2744, \"times_seen\": 49.0}, {\"site\": 382, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.060886492208305235, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08381753210694211, \"functional effect\": -2.2037, \"times_seen\": 2.0}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.00668986214724663, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08783697668930246, \"functional effect\": -1.8361, \"times_seen\": 3.0}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005457072307100101, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08710052796336312, \"functional effect\": -2.1947, \"times_seen\": 1.0}, {\"site\": 383, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03789531143349423, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08975758425010064, \"functional effect\": -0.5299, \"times_seen\": 10.0}, {\"site\": 384, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 384, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.011282430659445815, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": 0.08674953986816065, \"functional effect\": -0.9898, \"times_seen\": 4.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01642328609009767, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.08843158959324997, \"functional effect\": -0.4402, \"times_seen\": 5.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.026349716763812935, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.08904213917759747, \"functional effect\": -0.6615, \"times_seen\": 11.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.009740223840031365, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.08684232265353625, \"functional effect\": -0.2214, \"times_seen\": 2.0}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 385, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.16240444114942784, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.07812228216846545, \"functional effect\": -0.3296, \"times_seen\": 12.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.04012325149002779, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.08503255482068242, \"functional effect\": -1.0555, \"times_seen\": 13.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.6063971051829078, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.1331089470240997, \"functional effect\": -0.0239, \"times_seen\": 12.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.178222262786888, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.09892675805069326, \"functional effect\": -0.6202, \"times_seen\": 31.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0026164052576411892, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.08758931832940256, \"functional effect\": -1.1265, \"times_seen\": 2.0}, {\"site\": 386, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.025823107317930704, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.08587959745215307, \"functional effect\": -0.9047, \"times_seen\": 16.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.07868000455669194, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08279011551078388, \"functional effect\": -1.0617, \"times_seen\": 5.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02423882904360601, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08597395690354587, \"functional effect\": -0.5978, \"times_seen\": 4.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.032881211614760555, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08546047433515826, \"functional effect\": -1.0642, \"times_seen\": 18.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.022128431602987584, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08878198516704247, \"functional effect\": -2.8832, \"times_seen\": 4.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.018121932995087797, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08853577135610136, \"functional effect\": -0.4952, \"times_seen\": 4.0}, {\"site\": 387, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.002943742674962735, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08725239868230975, \"functional effect\": -1.5243, \"times_seen\": 1.0}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.02787549799034423, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.08913635915294896, \"functional effect\": -1.3162, \"times_seen\": 1.0}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0043920054116718486, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.0871648535051898, \"functional effect\": -2.9312, \"times_seen\": 1.0}, {\"site\": 388, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004449703407710151, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.08716136757319212, \"functional effect\": -3.0312, \"times_seen\": 1.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.006129085805041544, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08705996561405892, \"functional effect\": -1.5699, \"times_seen\": 1.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009911846130471856, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08683199254811352, \"functional effect\": -1.2761, \"times_seen\": 10.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.08695045623386341, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.0823168673381117, \"functional effect\": -0.9432, \"times_seen\": 4.0}, {\"site\": 389, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0025565434298514067, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08727581915298287, \"functional effect\": -0.1345, \"times_seen\": 1.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.011847738167687341, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08815157059699866, \"functional effect\": -0.8816, \"times_seen\": 1.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01277120244235706, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08666006589835974, \"functional effect\": -2.7257, \"times_seen\": 5.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0072542467891578664, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08699209382861114, \"functional effect\": -0.5996, \"times_seen\": 2.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.032207592694695815, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08550038660530679, \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 390, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.8402178612035914, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.15652881919694794, \"functional effect\": -0.0117, \"times_seen\": 6.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.02579850768291603, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08900812543292726, \"functional effect\": -2.4143, \"times_seen\": 1.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00189112409460366, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08731608297246643, \"functional effect\": -1.4106, \"times_seen\": 6.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.016350808725447256, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08842714712454151, \"functional effect\": -0.9108, \"times_seen\": 3.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05209332468939322, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.09064527758748098, \"functional effect\": -0.2401, \"times_seen\": 2.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.013760144583496734, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08660068229900848, \"functional effect\": -0.1483, \"times_seen\": 14.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01348601388111198, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08661713911128, \"functional effect\": -0.0429, \"times_seen\": 7.0}, {\"site\": 391, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027164438076002613, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08579978889306153, \"functional effect\": -1.3135, \"times_seen\": 9.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.03586569002872326, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08528386645780629, \"functional effect\": -1.6521, \"times_seen\": 4.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0388565172854398, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.0851072490176989, \"functional effect\": -0.5212, \"times_seen\": 9.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.06133221197496447, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08379164073049196, \"functional effect\": -0.7646, \"times_seen\": 22.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.019974970267454355, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08622842721484705, \"functional effect\": 0.0892, \"times_seen\": 6.0}, {\"site\": 392, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0058576459273020605, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08707634729487396, \"functional effect\": -1.234, \"times_seen\": 1.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.013780086114228993, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08659948527664181, \"functional effect\": -0.0749, \"times_seen\": 6.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.10527980593547184, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08127765227871989, \"functional effect\": -0.7207, \"times_seen\": 20.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.007569597973230139, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08697308075862055, \"functional effect\": -0.1288, \"times_seen\": 1.0}, {\"site\": 393, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.026248920003730362, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08903591828866447, \"functional effect\": -3.0099, \"times_seen\": 1.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.015251754988902773, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08835980844616917, \"functional effect\": -0.6754, \"times_seen\": 4.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0008378893944729465, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08737985106146288, \"functional effect\": -1.9101, \"times_seen\": 1.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03773926940813952, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08974787658671717, \"functional effect\": -2.2252, \"times_seen\": 13.0}, {\"site\": 394, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.016978266884081796, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08640772330157159, \"functional effect\": -0.6478, \"times_seen\": 26.0}, {\"site\": 395, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 395, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0042490785515253565, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": 0.08717348929834547, \"functional effect\": -2.5021, \"times_seen\": 1.0}, {\"site\": 395, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.007697942483339424, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": 0.086965343835277, \"functional effect\": -2.7401, \"times_seen\": 1.0}, {\"site\": 396, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.008669176480610961, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": 0.0879575678736279, \"functional effect\": -2.0107, \"times_seen\": 1.0}, {\"site\": 396, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.008755033190303478, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.08690164597615033, \"functional effect\": -2.4528, \"times_seen\": 2.0}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0056823482183327575, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.08708692833324358, \"functional effect\": -3.222, \"times_seen\": 1.0}, {\"site\": 397, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0002920395975269408, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.08741291785436714, \"functional effect\": -2.9552, \"times_seen\": 1.0}, {\"site\": 398, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.103585530841447, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": 0.0813731593608479, \"functional effect\": -1.2893, \"times_seen\": 18.0}, {\"site\": 398, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.013109012558764737, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": 0.08822867069818542, \"functional effect\": -2.3023, \"times_seen\": 8.0}, {\"site\": 398, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.008422046114783666, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.08692170597764985, \"functional effect\": -1.6759, \"times_seen\": 2.0}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013072659462894752, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.0866419598154198, \"functional effect\": -1.1369, \"times_seen\": 4.0}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.004551799733203756, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.08715519957494348, \"functional effect\": -2.3826, \"times_seen\": 1.0}, {\"site\": 399, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04190999625443083, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.09000770658998794, \"functional effect\": -0.0074, \"times_seen\": 23.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0761494514164085, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08293546059676332, \"functional effect\": -1.8128, \"times_seen\": 5.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.013131535763769799, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08663842403421702, \"functional effect\": -2.0965, \"times_seen\": 4.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.14066016419583957, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.0963843357246597, \"functional effect\": -0.2878, \"times_seen\": 59.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.08741359399450693, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08229044600176881, \"functional effect\": -0.374, \"times_seen\": 23.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.042442294334450695, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.0848959800571839, \"functional effect\": -0.4068, \"times_seen\": 7.0}, {\"site\": 400, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.025242261286199007, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08897381401974953, \"functional effect\": -1.9766, \"times_seen\": 1.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 1.561030226926438, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.2579766818121151, \"functional effect\": -0.7782, \"times_seen\": 3.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.030906367932292223, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.08932381712911941, \"functional effect\": -1.0488, \"times_seen\": 9.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.06779654930942258, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.09163730849218951, \"functional effect\": -1.5486, \"times_seen\": 18.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.05783847743447509, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.09100696820463326, \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 401, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.00884366403788837, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.08796820659412723, \"functional effect\": -2.6442, \"times_seen\": 1.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0073679587253149045, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08698523745958744, \"functional effect\": -2.8205, \"times_seen\": 2.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.019382395935681005, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08861315765030985, \"functional effect\": 0.1155, \"times_seen\": 32.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01972968525914484, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08624308889869643, \"functional effect\": -1.5414, \"times_seen\": 5.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.033610054107957636, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08541731102450185, \"functional effect\": -0.2703, \"times_seen\": 27.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0021381869481968438, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08756028941262758, \"functional effect\": -1.0143, \"times_seen\": 6.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.4029140702732042, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.06612631310375895, \"functional effect\": -0.4299, \"times_seen\": 42.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004501881408369429, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08715821526204898, \"functional effect\": -0.444, \"times_seen\": 19.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.012695626014037831, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08666460575579633, \"functional effect\": -0.8464, \"times_seen\": 12.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.022365291725317298, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08879656249462581, \"functional effect\": -1.2485, \"times_seen\": 8.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0032878471885497288, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08763009259359034, \"functional effect\": -0.7652, \"times_seen\": 32.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.027736538373442237, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08912777399984001, \"functional effect\": -0.4456, \"times_seen\": 15.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.05214997448882238, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08432664527859768, \"functional effect\": -1.177, \"times_seen\": 24.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.014861990928516552, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08653456699849355, \"functional effect\": -2.2208, \"times_seen\": 5.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.030537643113650315, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08930099061429302, \"functional effect\": -0.7947, \"times_seen\": 9.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.12865028429456998, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.07997162768756874, \"functional effect\": -1.4681, \"times_seen\": 26.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.10625624348182437, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.09411304962905281, \"functional effect\": 0.0325, \"times_seen\": 32.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.03502183507979188, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08533376492020751, \"functional effect\": -0.4711, \"times_seen\": 15.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.07781873885811376, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.09227611563171227, \"functional effect\": -0.6865, \"times_seen\": 18.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.00494851205506744, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.0871312369305522, \"functional effect\": -2.549, \"times_seen\": 1.0}, {\"site\": 402, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.13686737555623585, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.07951743169458987, \"functional effect\": -0.8437, \"times_seen\": 34.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.006157523223028549, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.08780457177029875, \"functional effect\": -2.3349, \"times_seen\": 1.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.08485138834919176, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.08243672250448915, \"functional effect\": -1.2607, \"times_seen\": 26.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.008761991082958123, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.08796322673365295, \"functional effect\": -3.0059, \"times_seen\": 4.0}, {\"site\": 403, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 1.0107247993447692, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.17616596694226538, \"functional effect\": -0.2443, \"times_seen\": 35.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01706856877001, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.0884711517563834, \"functional effect\": -1.9623, \"times_seen\": 2.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.12224679222221362, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.08032737567413052, \"functional effect\": -0.1177, \"times_seen\": 44.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.9969494440735078, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.17449187797812657, \"functional effect\": 0.0434, \"times_seen\": 34.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.006031673157263476, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.08706584421476618, \"functional effect\": -1.3395, \"times_seen\": 10.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0038635714614872916, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.0876650693819892, \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 404, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.025597415890872152, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08899571979238834, \"functional effect\": -2.695, \"times_seen\": 4.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.035168306958953705, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08532510171552397, \"functional effect\": -0.3577, \"times_seen\": 23.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.02055146524135932, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.0861939775752454, \"functional effect\": -2.5459, \"times_seen\": 4.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.030636871767650467, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08559352505569762, \"functional effect\": -0.8467, \"times_seen\": 7.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.029973110748088633, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08563291433435995, \"functional effect\": -0.7397, \"times_seen\": 24.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.06477513694514446, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08359191427019669, \"functional effect\": -0.5255, \"times_seen\": 20.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 1.2974057241096604, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.21489265393268936, \"functional effect\": -0.4055, \"times_seen\": 38.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03443905853261203, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08954281009681994, \"functional effect\": -0.2608, \"times_seen\": 19.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.038777692327792865, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08511189917478801, \"functional effect\": -0.5483, \"times_seen\": 89.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.5410096441591092, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.03004508267946129, \"functional effect\": -0.4969, \"times_seen\": 63.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.237799514825039, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.03707223311730869, \"functional effect\": -0.9469, \"times_seen\": 36.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.010135028163240082, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08804698266228587, \"functional effect\": -0.6264, \"times_seen\": 11.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0772133469082576, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08287432353423536, \"functional effect\": -0.4278, \"times_seen\": 16.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03465753593282968, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08535531551971304, \"functional effect\": -0.4112, \"times_seen\": 40.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.035924951601871445, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08528036332502638, \"functional effect\": -0.2147, \"times_seen\": 18.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07635550738160052, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08292361601038525, \"functional effect\": -0.2414, \"times_seen\": 94.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.033813427609693546, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08950398788958293, \"functional effect\": -0.3503, \"times_seen\": 68.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.001175287869379703, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08750186847835738, \"functional effect\": -0.4723, \"times_seen\": 22.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.062391769122470075, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08373012430792857, \"functional effect\": -0.2314, \"times_seen\": 8.0}, {\"site\": 405, \"wildtype\": \"R\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.015945160487194066, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08646962158158981, \"functional effect\": -0.0626, \"times_seen\": 15.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.04023200004108025, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08990307963299636, \"functional effect\": -2.9533, \"times_seen\": 1.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0026717803430186026, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08759268034211382, \"functional effect\": -1.3489, \"times_seen\": 9.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.010996057494148979, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08809954655118482, \"functional effect\": -2.9692, \"times_seen\": 2.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012008788682538192, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08670587480871735, \"functional effect\": -2.9548, \"times_seen\": 6.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004266966760501921, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08717240842686387, \"functional effect\": -2.8838, \"times_seen\": 3.0}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 406, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 2.3080714667630535, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.4329744543667638, \"functional effect\": -2.9451, \"times_seen\": 10.0}, {\"site\": 407, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 407, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.002389278519536165, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": 0.08728593842832037, \"functional effect\": -2.8913, \"times_seen\": 1.0}, {\"site\": 407, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.032487738071989375, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": 0.08548378558294212, \"functional effect\": -0.341, \"times_seen\": 39.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005923877938687461, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08707234983936103, \"functional effect\": -2.4914, \"times_seen\": 2.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.010572534837607091, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.0867922365490307, \"functional effect\": -1.9209, \"times_seen\": 2.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03729579016219618, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08519936901692893, \"functional effect\": -1.204, \"times_seen\": 27.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01757591709999673, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08637193548918623, \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 408, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 6.437095660422892e-05, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08743451544377691, \"functional effect\": -2.5928, \"times_seen\": 18.0}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0034484350709384375, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.08722188085325328, \"functional effect\": -2.5839, \"times_seen\": 1.0}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.002428091818622262, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.08757788613559361, \"functional effect\": -2.9764, \"times_seen\": 1.0}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 409, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.020728977749886593, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.08869590595693265, \"functional effect\": -2.8876, \"times_seen\": 2.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.013958910090544589, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08658875182005836, \"functional effect\": -0.7148, \"times_seen\": 6.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0069936269806903555, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08700781018593166, \"functional effect\": -1.6159, \"times_seen\": 4.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.047112083812066795, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08462162864133395, \"functional effect\": -0.2529, \"times_seen\": 12.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.779125010128572, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.025473788334842186, \"functional effect\": -2.0003, \"times_seen\": 10.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.026215490761880164, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08585624314016893, \"functional effect\": -2.7582, \"times_seen\": 4.0}, {\"site\": 410, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.013771323196609746, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08660001128278899, \"functional effect\": -2.2885, \"times_seen\": 1.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 2.2011712490818507, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.402051883985577, \"functional effect\": -0.3983, \"times_seen\": 1.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.013885829868302833, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.08827619010592286, \"functional effect\": -1.8486, \"times_seen\": 12.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.10119155274359518, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.09378323785917876, \"functional effect\": -0.7464, \"times_seen\": 16.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.014131215197961877, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.08829120611672095, \"functional effect\": -2.1803, \"times_seen\": 7.0}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 411, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006921217535096366, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.08701217725258571, \"functional effect\": -0.6686, \"times_seen\": 8.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.146812386379028, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.09679623427333342, \"functional effect\": -0.1443, \"times_seen\": 11.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.046119220963927225, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.08467988529708058, \"functional effect\": -0.4647, \"times_seen\": 16.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.11750285875322362, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.09484958062852351, \"functional effect\": -0.1293, \"times_seen\": 4.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.011908296706657813, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.08671191458005069, \"functional effect\": -2.1157, \"times_seen\": 2.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.19775016193209122, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.07623155865280125, \"functional effect\": -0.3731, \"times_seen\": 48.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.04039648174742718, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.08991333007020827, \"functional effect\": -0.043, \"times_seen\": 1.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.096253877576476, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.1869256200751809, \"functional effect\": -0.2426, \"times_seen\": 18.0}, {\"site\": 412, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.005098492376673111, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.08774014122456347, \"functional effect\": -2.4364, \"times_seen\": 5.0}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.01934067710425733, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.08861059523494803, \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 413, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.002360833450001998, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.08728765942894384, \"functional effect\": -3.1206, \"times_seen\": 1.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.03631207837988858, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08525748261754405, \"functional effect\": -2.6092, \"times_seen\": 5.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.14144755018170274, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.07926538521299793, \"functional effect\": -0.0135, \"times_seen\": 28.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.042087838149121336, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.084916840738988, \"functional effect\": -0.9425, \"times_seen\": 12.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.007542293944073633, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.086974726801573, \"functional effect\": -1.1213, \"times_seen\": 10.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005989167416994565, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08706840945036619, \"functional effect\": -0.8444, \"times_seen\": 13.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.020597383573089365, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08619123422300681, \"functional effect\": -0.2752, \"times_seen\": 11.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.8487900937536169, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.04854586588092038, \"functional effect\": -0.7688, \"times_seen\": 29.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.7199607047729776, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.05308034807905834, \"functional effect\": 0.0806, \"times_seen\": 24.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03235703018260394, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08941367940414659, \"functional effect\": 0.171, \"times_seen\": 21.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.6369476488406408, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.13595772157846095, \"functional effect\": -0.1677, \"times_seen\": 39.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0447449951518209, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08476058476695189, \"functional effect\": 0.0495, \"times_seen\": 45.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.06842753904360034, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.09167739655372906, \"functional effect\": 0.0532, \"times_seen\": 15.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.17517132756338322, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.07743400211066785, \"functional effect\": 0.1462, \"times_seen\": 42.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016709868357274785, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08642380006235893, \"functional effect\": -0.0824, \"times_seen\": 4.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.09603191807845167, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.0934484318342407, \"functional effect\": -0.1734, \"times_seen\": 54.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.4994896028579287, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.12360182492017378, \"functional effect\": -0.2119, \"times_seen\": 40.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03909434834533026, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.0898322135993784, \"functional effect\": 0.0517, \"times_seen\": 62.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.06737832311149027, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08344121775834905, \"functional effect\": 0.2189, \"times_seen\": 23.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.006964209935842079, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08700958432299923, \"functional effect\": -0.3319, \"times_seen\": 5.0}, {\"site\": 414, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.3045131404775861, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.10797696576967745, \"functional effect\": 0.1926, \"times_seen\": 19.0}, {\"site\": 415, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 415, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.002157252126341814, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": 0.08756144652726307, \"functional effect\": -1.2658, \"times_seen\": 1.0}, {\"site\": 415, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0803604383777833, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": 0.08269373872075785, \"functional effect\": -0.8129, \"times_seen\": 14.0}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005072522394500356, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.08712374767635668, \"functional effect\": -2.7621, \"times_seen\": 1.0}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01341165440760912, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.0866216036520645, \"functional effect\": -2.4187, \"times_seen\": 4.0}, {\"site\": 416, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.004931719813073434, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.08772999923187023, \"functional effect\": -2.8538, \"times_seen\": 4.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.019724906990072778, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08624337454005175, \"functional effect\": -1.2512, \"times_seen\": 4.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.009071184041861372, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08688260451658902, \"functional effect\": -2.7506, \"times_seen\": 5.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.013635592188682696, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08660815913069439, \"functional effect\": -2.9881, \"times_seen\": 1.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.5821143819309046, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.058402258212107726, \"functional effect\": -0.0155, \"times_seen\": 29.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.014760494775481626, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08832972567228367, \"functional effect\": -2.0778, \"times_seen\": 5.0}, {\"site\": 417, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.894013012134163, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.047047743297336075, \"functional effect\": -1.6177, \"times_seen\": 12.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006985491298496102, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08700830084394874, \"functional effect\": -2.9341, \"times_seen\": 1.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.03356832196284535, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.0894887829649341, \"functional effect\": -2.0424, \"times_seen\": 4.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.011442122993813777, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08673993806774326, \"functional effect\": -0.3202, \"times_seen\": 14.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.016926308099619355, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08641083533910691, \"functional effect\": -0.9485, \"times_seen\": 10.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.020026569939070423, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08622534320967974, \"functional effect\": -2.8359, \"times_seen\": 6.0}, {\"site\": 418, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 419, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 419, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0017711636150693618, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": 0.08753801680413976, \"functional effect\": -0.3505, \"times_seen\": 1.0}, {\"site\": 420, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.08260416299225712, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": 0.08256523077819897, \"functional effect\": -0.1813, \"times_seen\": 1.0}, {\"site\": 420, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.4231227159766495, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": 0.06520650162206111, \"functional effect\": -2.2681, \"times_seen\": 1.0}, {\"site\": 420, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0566286937759327, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.08406526658234596, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01064620348716889, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.08678780477139587, \"functional effect\": -2.5108, \"times_seen\": 2.0}, {\"site\": 421, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.013905313115542583, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.08659196870321266, \"functional effect\": -0.928, \"times_seen\": 10.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0197162509279722, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08863366605126062, \"functional effect\": -0.2721, \"times_seen\": 7.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.005522789082640735, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08709656050293797, \"functional effect\": -0.7344, \"times_seen\": 2.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0019363633100715459, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.0875480411552752, \"functional effect\": -1.9279, \"times_seen\": 1.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005938736234956974, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08707145308705233, \"functional effect\": -0.5957, \"times_seen\": 1.0}, {\"site\": 422, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.023532222068654463, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08886841504698868, \"functional effect\": -0.6278, \"times_seen\": 7.0}, {\"site\": 423, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 423, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.008367712768962646, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": 0.08793919029281978, \"functional effect\": -1.765, \"times_seen\": 13.0}, {\"site\": 423, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00912367646383371, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": 0.08687944335276714, \"functional effect\": -2.888, \"times_seen\": 3.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.025258256046183623, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08897480045322902, \"functional effect\": -0.6326, \"times_seen\": 7.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.062236915997474114, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08373911204748213, \"functional effect\": -0.1615, \"times_seen\": 9.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -3.6475600723443984, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.0069765150782020065, \"functional effect\": -0.5222, \"times_seen\": 16.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.017303113627583945, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08638826935819559, \"functional effect\": -0.4526, \"times_seen\": 12.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.5195721124969632, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.06098973399377633, \"functional effect\": -0.2103, \"times_seen\": 48.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.05226906196360951, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08431968481051474, \"functional effect\": -1.0111, \"times_seen\": 4.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.013092151948013926, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08664078918985078, \"functional effect\": -0.4356, \"times_seen\": 2.0}, {\"site\": 424, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.19139198112343525, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.09983395059585988, \"functional effect\": -0.3463, \"times_seen\": 27.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.005631241591021087, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08709001339134449, \"functional effect\": -0.3824, \"times_seen\": 5.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01844073845023981, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08632017547896965, \"functional effect\": -0.1124, \"times_seen\": 9.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.019929196325326085, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08623116312059396, \"functional effect\": -0.96, \"times_seen\": 9.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0209221018674208, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08617183669249245, \"functional effect\": -0.1979, \"times_seen\": 4.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.015716848761295282, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08648330679585046, \"functional effect\": -0.2893, \"times_seen\": 4.0}, {\"site\": 425, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.001809100907455127, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08754031874523525, \"functional effect\": -0.8063, \"times_seen\": 18.0}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014024314756157015, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.08658482640281714, \"functional effect\": -2.3704, \"times_seen\": 3.0}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0022702865279504857, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.08729313797894969, \"functional effect\": -2.3682, \"times_seen\": 1.0}, {\"site\": 426, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005333391388437837, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.08710799533157888, \"functional effect\": -2.1454, \"times_seen\": 1.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02225600522922095, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08878983626534119, \"functional effect\": -1.1343, \"times_seen\": 6.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07415275720044155, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08305032298684527, \"functional effect\": -0.092, \"times_seen\": 30.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.01904621437294726, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08859251112533531, \"functional effect\": -1.7059, \"times_seen\": 1.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0011869060781404602, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08735871469074637, \"functional effect\": -0.7532, \"times_seen\": 5.0}, {\"site\": 427, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 428, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02141489945662209, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": 0.08614240703457397, \"functional effect\": -1.2965, \"times_seen\": 7.0}, {\"site\": 428, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 428, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005462591605207593, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": 0.0871001947447369, \"functional effect\": -2.9554, \"times_seen\": 1.0}, {\"site\": 429, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 429, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008227033756985936, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": 0.08793061564959453, \"functional effect\": -2.7205, \"times_seen\": 3.0}, {\"site\": 430, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011101507126315616, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": 0.08676041951838286, \"functional effect\": -1.3058, \"times_seen\": 4.0}, {\"site\": 430, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0007204896768400808, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": 0.08738696191091537, \"functional effect\": -2.811, \"times_seen\": 2.0}, {\"site\": 430, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02243506460952552, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.08608151515111645, \"functional effect\": -0.0207, \"times_seen\": 1.0}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.002309269515566341, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.08729077926747893, \"functional effect\": -1.4261, \"times_seen\": 2.0}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.017999969086264594, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.08634655187898777, \"functional effect\": -0.5007, \"times_seen\": 7.0}, {\"site\": 431, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.4173777822001679, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.03273333855391654, \"functional effect\": -0.4859, \"times_seen\": 15.0}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07743622155424634, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.08286152168883097, \"functional effect\": -0.0533, \"times_seen\": 24.0}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0718234529013866, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.08318452024957736, \"functional effect\": -0.5215, \"times_seen\": 19.0}, {\"site\": 432, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.019327978335603773, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.08860981527767016, \"functional effect\": -1.2557, \"times_seen\": 9.0}, {\"site\": 433, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.02214537231067084, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": 0.08609880200326216, \"functional effect\": -2.5145, \"times_seen\": 10.0}, {\"site\": 433, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.035604129889482444, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": 0.0852993297966193, \"functional effect\": -2.0667, \"times_seen\": 22.0}, {\"site\": 433, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"437\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005201526019453414, \"epitope\": \"all\", \"reference_site\": \"437\", \"IC90\": 0.08711595754991523, \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 2.2196879757623447, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.4072454039414149, \"functional effect\": -1.4674, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0716370069971056, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.09188157220004771, \"functional effect\": -0.3883, \"times_seen\": 5.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 2.8267217513886607, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.6202854106686688, \"functional effect\": -0.1849, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.018943126149220984, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.08629012155675665, \"functional effect\": -1.9279, \"times_seen\": 2.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.034156840046733444, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.08952529553967223, \"functional effect\": -2.7564, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 4.31403165393204, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 1.7390675842719943, \"functional effect\": -2.0882, \"times_seen\": 8.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07359384521127345, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.09200628279945292, \"functional effect\": -1.1017, \"times_seen\": 6.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.024348329127667847, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08891870055850218, \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03905964416611906, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08509526703081612, \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": 5.538996044076828, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 4.065064913704812, \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.008901931332727315, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08689279792433517, \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.05048334821144088, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.09054417835182334, \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.010750965075113132, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08678150288646341, \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 3.8431720902538715, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 1.2547973927172282, \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.07132281860057581, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.09186156452010319, \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0016962118857730525, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08732788042086938, \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02815326661008016, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08915352263269342, \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03301983272163172, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08945476724847543, \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 5.54289163159549, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 4.076056297889048, \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 6.175564999763519, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 6.319661765879376, \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.007251794629236257, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08787119602379516, \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.024591079184530476, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08893366341279284, \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 6.982880217397844, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 11.059103728406948, \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.6135466615753649, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.05714359789253478, \"functional effect\": -2.7496, \"times_seen\": 5.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.023353451465724276, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08602673505379368, \"functional effect\": 0.028, \"times_seen\": 21.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0030228482806519416, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08761399789195644, \"functional effect\": -2.979, \"times_seen\": 1.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"D\", \"log2 fold change IC90\": 2.988455377551563, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.693870205249894, \"functional effect\": 0.1224, \"times_seen\": 14.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.035473870658860915, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08530703172001454, \"functional effect\": 0.3113, \"times_seen\": 15.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": 2.9965965061402136, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.6977967834670071, \"functional effect\": -1.206, \"times_seen\": 5.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0360832316617112, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.0852710076121399, \"functional effect\": 0.0017, \"times_seen\": 24.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.6423402061249434, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.1364668601734881, \"functional effect\": 0.221, \"times_seen\": 12.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.017247475646332885, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08639160101281233, \"functional effect\": -0.8004, \"times_seen\": 13.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.09629116071546798, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.09346522540041101, \"functional effect\": -0.8499, \"times_seen\": 18.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0310241811057953, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08933111177681977, \"functional effect\": -0.0401, \"times_seen\": 10.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0641958085095033, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08362548816908723, \"functional effect\": 0.2118, \"times_seen\": 36.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.053388047247011974, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.09072666219037122, \"functional effect\": -0.534, \"times_seen\": 8.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.014135946818360534, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08829149568668904, \"functional effect\": 0.1906, \"times_seen\": 16.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.10473488765582531, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08130835734288568, \"functional effect\": -0.1206, \"times_seen\": 36.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.05492170810253917, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.09082316069579882, \"functional effect\": 0.2856, \"times_seen\": 44.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06016150288658664, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.0838596630389731, \"functional effect\": 0.0087, \"times_seen\": 29.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": 2.214014987414679, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.4056471714545226, \"functional effect\": -0.4789, \"times_seen\": 13.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.009980778110922694, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08803756935920867, \"functional effect\": -1.2464, \"times_seen\": 5.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03889378752157989, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08981972615749124, \"functional effect\": -0.2806, \"times_seen\": 16.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.03734793943220056, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.0897235358421085, \"functional effect\": -0.1303, \"times_seen\": 10.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0015214834732657355, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08733845755985287, \"functional effect\": 0.0594, \"times_seen\": 19.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.008690296835848927, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08690554549879138, \"functional effect\": 0.0273, \"times_seen\": 3.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.039688253387752566, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08505819750739711, \"functional effect\": -2.2021, \"times_seen\": 6.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009222485490119184, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08687349325313175, \"functional effect\": -1.4385, \"times_seen\": 1.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.014224353018482395, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08657282173308299, \"functional effect\": -0.74, \"times_seen\": 7.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003440124721236268, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08722238327850511, \"functional effect\": 0.3662, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.05333137591372515, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.09072309837419282, \"functional effect\": -1.6793, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.010659543765995289, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.08678700226765895, \"functional effect\": -2.4152, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.024871845912123842, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.08895097271434353, \"functional effect\": -0.8693, \"times_seen\": 2.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0020605795148163743, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.08730582764186336, \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.036745949094769005, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.08968610490017663, \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 2.143007952723105, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.38616526289321135, \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04245144687793163, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.09004149326964564, \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 5.862837703804692, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 5.088075400412939, \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.04298636846488809, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.09007488498967685, \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 8.123807368845661, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 24.387833815873897, \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 7.37017300806705, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 14.464608337530171, \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": 5.195399508592827, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 3.2035729761944056, \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 7.864235679383465, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 20.372032597671065, \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 7.4415666110137595, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 15.198414847905317, \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 4.795873800812939, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 2.428652614819242, \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 8.842390985462522, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 40.13178251073179, \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 8.512903195889878, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 31.93763418139873, \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 5.738321281925659, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 4.667349904943544, \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 8.334019965587428, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 28.21327643144618, \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 7.838913038137146, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 20.017576082528603, \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.09502985121388813, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.09338354697556539, \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.1553055122385894, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.09736775298376125, \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 2.6180502237328414, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.5367538614399799, \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.025699024544130897, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.0890019879595504, \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.21505791555674103, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.07532248621012497, \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.00467181840134902, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.0877141961020921, \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.6048628843054624, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.02874429510029863, \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": 4.53776743712091, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 2.030802277959357, \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 4.158472018022565, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 1.5613071318523768, \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -1.086135741141287, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.041181683119628616, \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 2.0214230232354664, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.35495434265884995, \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 6.428953639737035, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 7.533059821369193, \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 4.376693391346625, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 1.8162662903892821, \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 4.887100797879884, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 2.587184865029817, \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": 3.423040787545209, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.9377811165312595, \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -1.3117480748720514, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.03521989141445535, \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 8.527559438091597, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 32.26374010543718, \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.030958171499268293, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.08557446481516824, \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 4.543210938898914, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 2.0384792694339366, \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 6.259869788854806, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 6.699958387360318, \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": 5.768266193421393, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 4.765238886406571, \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 4.308975912488583, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 1.7329839088707804, \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 5.371239489967127, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 3.6188262368738915, \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 9.560692549436858, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 66.02657454192249, \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 10.094253736362692, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 95.57332347177515, \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 7.788780422728727, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 19.333926660308748, \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 9.637017433501285, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 69.61372065485382, \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 4.762890517581225, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 2.37375800228452, \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 7.124736654802657, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 12.201773929511178, \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 5.1363223041832695, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 3.0750388776310174, \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 4.748470280867727, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 2.350149652104242, \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 5.679285590297246, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 4.480214905383568, \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.012626241756451306, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08819915156971479, \"functional effect\": -2.6941, \"times_seen\": 1.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04372552267030678, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08482050153341139, \"functional effect\": -0.4238, \"times_seen\": 2.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.010041275931724915, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08682420286068616, \"functional effect\": 0.2586, \"times_seen\": 9.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.024502426827956343, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08595824985966248, \"functional effect\": -0.1014, \"times_seen\": 12.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.1422528651472032, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.07922115147929218, \"functional effect\": 0.2543, \"times_seen\": 80.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0644823723472241, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.09142703973770601, \"functional effect\": 0.3976, \"times_seen\": 23.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.6124951071198613, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.1336727643675531, \"functional effect\": 0.4215, \"times_seen\": 9.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"V\", \"log2 fold change IC90\": 4.809922707708367, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 2.452418264002409, \"functional effect\": -0.095, \"times_seen\": 5.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 1.7345032811338108, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.290938399353042, \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.12181139783678986, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.09513326771960563, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03576482216556429, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.08528982939651382, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.7889040352138998, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.025301703143689465, \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 9.12890596764632, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 48.9483496694263, \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 8.233200206513045, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 26.30896434819447, \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.07071798901562786, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.09182306092405804, \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.07976115397976344, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.09240043798189643, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 2.380743676803447, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": 0.45534313014053635, \"functional effect\": -1.0316, \"times_seen\": 30.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.09334562794029927, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": 0.09327459326761309, \"functional effect\": -1.5391, \"times_seen\": 5.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0017173972228807328, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.0873265980590746, \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.0237668893826916, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.08888287146906654, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.06088983500723929, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.09119965527200956, \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": 1.4395395223826493, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.2371417967964674, \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0457442095608834, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08470189968635855, \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02664793280623477, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08583051193270921, \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 1.3025480655678017, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.2156599839202064, \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.10431597213204465, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08133197028797372, \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.05217005031640829, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08432547183905251, \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.11348908758282931, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08081647624143438, \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.022785495120793583, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08606060849711317, \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.13116012170148247, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.09575173693985288, \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.05469737471282668, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08417787913622207, \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.14563534618836363, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.09671729410190255, \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 1.319620984074853, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.21822727470169231, \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.22780013644550592, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.10238544071808076, \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.9879822730825503, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.17341067524613024, \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": 3.4420652676260657, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.9502293108024831, \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0288550407839353, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08569930445587008, \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 1.0368229726667353, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.17938178650002382, \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.028242901218452736, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08915906191099734, \"functional effect\": 0.1313, \"times_seen\": 22.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.005028188829465829, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.08773586568975404, \"functional effect\": -2.3815, \"times_seen\": 1.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0033881064704387454, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.08722552825195927, \"functional effect\": -1.9525, \"times_seen\": 1.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.2408438192460825, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.10331532443554983, \"functional effect\": -0.4406, \"times_seen\": 13.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0625765691397462, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.0837193997008528, \"functional effect\": -0.9062, \"times_seen\": 9.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.010284168300965776, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.0868095863543741, \"functional effect\": -0.6085, \"times_seen\": 3.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.00858614592811019, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": 0.08691181960240826, \"functional effect\": -3.0722, \"times_seen\": 2.0}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.007859875934199925, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": 0.08695558306981971, \"functional effect\": -3.0305, \"times_seen\": 3.0}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.013371282114138242, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08662402769986144, \"functional effect\": -0.0855, \"times_seen\": 21.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.012376973764540809, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08668374973343303, \"functional effect\": 0.2134, \"times_seen\": 3.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.08697413435500397, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08231551632995904, \"functional effect\": 0.1937, \"times_seen\": 17.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016518476776342057, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08643526602326906, \"functional effect\": 0.2447, \"times_seen\": 4.0}, {\"site\": 452, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.011588499295959264, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08673113785221574, \"functional effect\": -0.0584, \"times_seen\": 5.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.013138128795947104, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.08663802810257792, \"functional effect\": -0.306, \"times_seen\": 1.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05075840193628489, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.08440802301547193, \"functional effect\": -0.6037, \"times_seen\": 11.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.6081055111390307, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.057359522932014524, \"functional effect\": -0.8152, \"times_seen\": 5.0}, {\"site\": 453, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.017815684772689272, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.08635758215976355, \"functional effect\": 0.2206, \"times_seen\": 2.0}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.057458333205431276, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.09098299140062173, \"functional effect\": -2.4922, \"times_seen\": 4.0}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0027254422144098963, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.08726560222111023, \"functional effect\": -3.0332, \"times_seen\": 1.0}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 454, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.019812810846722102, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.08863959852192566, \"functional effect\": -3.0393, \"times_seen\": 3.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.034926043646438594, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.0853394310622572, \"functional effect\": -0.1772, \"times_seen\": 10.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0002110283990954511, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08741782646211674, \"functional effect\": -0.5111, \"times_seen\": 2.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0014443389404132849, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08751818839777341, \"functional effect\": -0.2319, \"times_seen\": 1.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.013425631541639959, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08662076444775241, \"functional effect\": 0.0638, \"times_seen\": 17.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.22856439778369544, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.10243969332273364, \"functional effect\": -0.1467, \"times_seen\": 10.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.6203345201126272, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.1344011014436891, \"functional effect\": -0.064, \"times_seen\": 20.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.010669064620109345, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08678642953146891, \"functional effect\": 0.3853, \"times_seen\": 5.0}, {\"site\": 455, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.002600914533046664, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08727313496490581, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02584844382736672, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08587808925391072, \"functional effect\": -0.7345, \"times_seen\": 15.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.023667309613850517, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08600802198259239, \"functional effect\": -0.2959, \"times_seen\": 7.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0019637393536168623, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08754970245004562, \"functional effect\": -0.5048, \"times_seen\": 2.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.06688375841586663, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.09157934804825676, \"functional effect\": -0.3614, \"times_seen\": 5.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.030703495622388877, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.0893112572640457, \"functional effect\": -0.2345, \"times_seen\": 13.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.010143421066831937, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08681805578474167, \"functional effect\": -0.5813, \"times_seen\": 2.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.004640802371854296, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08771231038350819, \"functional effect\": -0.1484, \"times_seen\": 3.0}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 456, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -1.474747266975937, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.03145722195071722, \"functional effect\": -0.2011, \"times_seen\": 4.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.014068814752658972, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08658215573095643, \"functional effect\": -1.2551, \"times_seen\": 4.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03315379941649773, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08544432866226952, \"functional effect\": -0.0782, \"times_seen\": 2.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.04691473956092248, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.09032048766725664, \"functional effect\": -0.1905, \"times_seen\": 3.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -2.7675935308643846, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.01283910827479152, \"functional effect\": -0.0494, \"times_seen\": 15.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.061657482831508084, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08377275114832214, \"functional effect\": -0.3183, \"times_seen\": 8.0}, {\"site\": 457, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.006784153973593804, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08784271773601161, \"functional effect\": -0.997, \"times_seen\": 3.0}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.017697279711694686, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.08850971493239825, \"functional effect\": 0.4167, \"times_seen\": 1.0}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.003518975782093416, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.08721761623535866, \"functional effect\": -1.7193, \"times_seen\": 1.0}, {\"site\": 458, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.023973105729895177, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.08598979350662998, \"functional effect\": -3.0553, \"times_seen\": 3.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.07146695916560042, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08320507790294775, \"functional effect\": -0.9144, \"times_seen\": 8.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.020809473390016972, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08617856422765253, \"functional effect\": -2.0544, \"times_seen\": 2.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.015971948257735732, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08646801604000853, \"functional effect\": -0.027, \"times_seen\": 3.0}, {\"site\": 459, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.07643490538468284, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08291905247605293, \"functional effect\": 0.245, \"times_seen\": 4.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.004664287007909087, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08714840432826669, \"functional effect\": -3.0357, \"times_seen\": 1.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02425418657960311, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08597304171282781, \"functional effect\": -3.1966, \"times_seen\": 1.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0025572677294957128, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.0872757753364956, \"functional effect\": -1.6084, \"times_seen\": 1.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008128275029710983, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08693940735122171, \"functional effect\": -1.9766, \"times_seen\": 8.0}, {\"site\": 460, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0109881995273562, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08676723384892006, \"functional effect\": -2.697, \"times_seen\": 2.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.027409407191531253, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.0891075665631627, \"functional effect\": -1.2792, \"times_seen\": 12.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.020974378466717257, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.08871099430864836, \"functional effect\": -0.6701, \"times_seen\": 1.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0038258670655789344, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.08719906520499202, \"functional effect\": -2.6458, \"times_seen\": 1.0}, {\"site\": 461, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02709187763640245, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.08580410430746728, \"functional effect\": -0.29, \"times_seen\": 1.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0021084177626938144, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08730293272057982, \"functional effect\": -2.4968, \"times_seen\": 1.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.015984510037220827, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08646726315225997, \"functional effect\": -1.5638, \"times_seen\": 3.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.005265702039264271, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08711208241975052, \"functional effect\": -1.4526, \"times_seen\": 16.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.019877855516722862, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08623423186089685, \"functional effect\": -1.101, \"times_seen\": 9.0}, {\"site\": 462, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01798401298300512, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08634750687091454, \"functional effect\": -2.4745, \"times_seen\": 2.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.002750777063808906, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08726406978257317, \"functional effect\": -2.7086, \"times_seen\": 2.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005515710524813981, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08709698784172755, \"functional effect\": -2.6585, \"times_seen\": 1.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.012292912111172356, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08817877581806827, \"functional effect\": -0.9854, \"times_seen\": 6.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.050237965038620325, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08443847780516245, \"functional effect\": -1.8776, \"times_seen\": 8.0}, {\"site\": 463, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 2.2885740781105445e-05, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.08743200126892361, \"functional effect\": -2.7075, \"times_seen\": 1.0}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.02584827661620424, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.08901119601662001, \"functional effect\": -2.9013, \"times_seen\": 1.0}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005363738562107731, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.08710616302912774, \"functional effect\": -2.6267, \"times_seen\": 1.0}, {\"site\": 464, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004174178064047002, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.08717801520725449, \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.023135981764806926, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08884401043512268, \"functional effect\": -2.1352, \"times_seen\": 2.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.1465221894570469, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.09677676574845344, \"functional effect\": -0.349, \"times_seen\": 5.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.02318573775540983, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08884707456014694, \"functional effect\": -0.6158, \"times_seen\": 1.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.026756785906552186, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08906726674809853, \"functional effect\": -0.4385, \"times_seen\": 23.0}, {\"site\": 465, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.009252178342548888, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08799311924585025, \"functional effect\": -0.6714, \"times_seen\": 9.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.004777376028834443, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.0877206141190022, \"functional effect\": -1.8312, \"times_seen\": 6.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.12256150744012652, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.08030985465294656, \"functional effect\": -0.6392, \"times_seen\": 12.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07980929752369466, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.08272533556076539, \"functional effect\": -0.7065, \"times_seen\": 31.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.007358750394485752, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.08698579266451803, \"functional effect\": -2.4014, \"times_seen\": 1.0}, {\"site\": 466, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01353618990357382, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.08661412667426596, \"functional effect\": -0.3892, \"times_seen\": 6.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.12880037661989296, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.09559524856412002, \"functional effect\": -0.5468, \"times_seen\": 43.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.2362678265777094, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.2059762885648034, \"functional effect\": -0.5988, \"times_seen\": 5.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.019673407123868537, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.08624645322362615, \"functional effect\": 0.0284, \"times_seen\": 33.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.011381879103111517, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.0881231102658496, \"functional effect\": 0.3772, \"times_seen\": 7.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.004785892860481801, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.0877211319719694, \"functional effect\": -0.8349, \"times_seen\": 6.0}, {\"site\": 467, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.004934079567932347, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08713210858167074, \"functional effect\": -2.4359, \"times_seen\": 1.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.006992815744927825, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08700785911094013, \"functional effect\": -0.5909, \"times_seen\": 6.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.006800807895688672, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08784373176474261, \"functional effect\": -0.101, \"times_seen\": 12.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.13773730243745294, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.09618926130007964, \"functional effect\": -0.7486, \"times_seen\": 23.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.033095715381171516, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08544776878729336, \"functional effect\": -1.4314, \"times_seen\": 13.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.09666699231617619, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08176432685927826, \"functional effect\": -0.2862, \"times_seen\": 41.0}, {\"site\": 468, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.02183998788509517, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08876423640842511, \"functional effect\": -0.6964, \"times_seen\": 6.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.07531256732678064, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.09211595772046591, \"functional effect\": -0.9636, \"times_seen\": 4.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.013484029799743053, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08661725823248388, \"functional effect\": 0.1237, \"times_seen\": 5.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0022119988781385096, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08756476933326153, \"functional effect\": 0.0321, \"times_seen\": 1.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.006881877396416561, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08701454997703154, \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03745249654156528, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.0897300386533314, \"functional effect\": -1.1749, \"times_seen\": 18.0}, {\"site\": 469, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.002832678924244711, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.0872591159381394, \"functional effect\": -0.4416, \"times_seen\": 9.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.009091102498855556, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.0868814049869406, \"functional effect\": -2.7598, \"times_seen\": 2.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.05677892770834914, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.08405651296660327, \"functional effect\": -2.3124, \"times_seen\": 1.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.047627877241951444, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.09036514496723223, \"functional effect\": 0.0095, \"times_seen\": 16.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.028147780171183273, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.08574132761413411, \"functional effect\": -0.6, \"times_seen\": 7.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.004045078122339622, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.0871858167037186, \"functional effect\": -1.6109, \"times_seen\": 1.0}, {\"site\": 470, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.003214303440258132, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.08723603703857095, \"functional effect\": -2.3923, \"times_seen\": 1.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.6154364937168773, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.13394557625962097, \"functional effect\": -0.3826, \"times_seen\": 6.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.5361663629928358, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.06029223344704185, \"functional effect\": -1.3723, \"times_seen\": 11.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.005819331338807346, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.08707865986864882, \"functional effect\": -1.1986, \"times_seen\": 7.0}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 471, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0029304832188161915, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.08760838879713136, \"functional effect\": -1.3102, \"times_seen\": 29.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.021265617717610263, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.08872890435253306, \"functional effect\": -1.0243, \"times_seen\": 9.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.013984890681789, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.08658719251150894, \"functional effect\": -0.6215, \"times_seen\": 4.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.22828601504361445, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.07463500939856135, \"functional effect\": -0.4959, \"times_seen\": 19.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.07056251891601885, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.08325725636962208, \"functional effect\": -0.6461, \"times_seen\": 23.0}, {\"site\": 472, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.14089033193897033, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.07929600613295971, \"functional effect\": -0.1795, \"times_seen\": 17.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0310696501956756, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.0855678526338343, \"functional effect\": -0.5457, \"times_seen\": 7.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004965692069897561, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.08713019935366492, \"functional effect\": -2.2789, \"times_seen\": 1.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.07308276324373124, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.08311194121014794, \"functional effect\": -0.7248, \"times_seen\": 44.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.007841168894413199, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.08695671060686148, \"functional effect\": -2.7481, \"times_seen\": 2.0}, {\"site\": 473, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05445329295651796, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.08419212194024844, \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.025625845271911647, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08589134071240413, \"functional effect\": -2.7271, \"times_seen\": 1.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.006022282618219079, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08706641093042489, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.023433940289555106, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08602193570439727, \"functional effect\": -0.5291, \"times_seen\": 7.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00871557846754971, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08690402258876473, \"functional effect\": -2.4417, \"times_seen\": 2.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0425260481192983, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08489105167449784, \"functional effect\": 0.3592, \"times_seen\": 13.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.015003425262830552, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08652608401447452, \"functional effect\": -0.6824, \"times_seen\": 3.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07162226906436513, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08319612114056195, \"functional effect\": -0.3226, \"times_seen\": 16.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.028373089117703844, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08572793824268783, \"functional effect\": -0.1796, \"times_seen\": 7.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.048816003917358304, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08452174378996481, \"functional effect\": -0.2299, \"times_seen\": 23.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.053871212356614906, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.09075705204941177, \"functional effect\": -0.0419, \"times_seen\": 17.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.002014659018067743, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08730860660114857, \"functional effect\": -0.5132, \"times_seen\": 12.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.007510254519265257, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.0869766583609695, \"functional effect\": -0.5954, \"times_seen\": 5.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.003072441493355602, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.0876170097095565, \"functional effect\": 0.1628, \"times_seen\": 19.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0416437622720841, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.0849429830100402, \"functional effect\": -0.0043, \"times_seen\": 7.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.024565555217808715, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08595448864399752, \"functional effect\": -0.5627, \"times_seen\": 18.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.6065457236858998, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.057421571420542585, \"functional effect\": -0.0281, \"times_seen\": 46.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.1000629205533775, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08157208994220713, \"functional effect\": -0.0542, \"times_seen\": 47.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.041708841022520655, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08493915139049724, \"functional effect\": 0.0493, \"times_seen\": 9.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.005620495240857525, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08709066211005413, \"functional effect\": -1.0221, \"times_seen\": 1.0}, {\"site\": 474, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06880801737359246, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08335856942575554, \"functional effect\": -0.9565, \"times_seen\": 11.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.024883262905381103, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08593556198634154, \"functional effect\": -3.0352, \"times_seen\": 4.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.006106909892492956, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08706130383798522, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.010453056225265692, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08806639390098533, \"functional effect\": -0.1629, \"times_seen\": 17.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.006252347156324462, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.087052527679992, \"functional effect\": -2.4135, \"times_seen\": 1.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.003670561615448505, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08765334196262063, \"functional effect\": -0.1663, \"times_seen\": 4.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -2.291582842170362, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.017857816537421942, \"functional effect\": 0.1619, \"times_seen\": 23.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.01557358668168313, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08649189516221728, \"functional effect\": -0.3474, \"times_seen\": 6.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.053529882742607435, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08424602713072393, \"functional effect\": -0.5754, \"times_seen\": 15.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03949473644159171, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08506960761567434, \"functional effect\": 0.104, \"times_seen\": 12.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.5639666701490734, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.129251149510151, \"functional effect\": -0.2191, \"times_seen\": 25.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01331056750032799, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.0866276732763059, \"functional effect\": -0.1538, \"times_seen\": 18.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03144939565536643, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08554533247090315, \"functional effect\": -0.2939, \"times_seen\": 20.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.017250856132090386, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08639139858248135, \"functional effect\": -0.2213, \"times_seen\": 26.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0539388265181997, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.09076130562040773, \"functional effect\": -2.0058, \"times_seen\": 6.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.013892007866427636, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08827656812850503, \"functional effect\": 0.1862, \"times_seen\": 12.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.28164317886466067, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.07192510176742672, \"functional effect\": -0.1985, \"times_seen\": 66.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07802616605479909, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08282764501754315, \"functional effect\": 0.0548, \"times_seen\": 28.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.17054961631054916, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.07768246172027446, \"functional effect\": 0.1097, \"times_seen\": 40.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05886282145532677, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.0839351855968573, \"functional effect\": 0.084, \"times_seen\": 22.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.015317481509594853, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08650725044333503, \"functional effect\": -1.0061, \"times_seen\": 11.0}, {\"site\": 475, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.11444051185312733, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.09464846102040096, \"functional effect\": -0.1538, \"times_seen\": 11.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.019170355448582407, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08627653164395196, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.005460886061107801, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08776218362853429, \"functional effect\": -0.5907, \"times_seen\": 6.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.020230595836559947, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08621315008594235, \"functional effect\": -0.8606, \"times_seen\": 19.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -2.8470499009200645, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.012151114426970543, \"functional effect\": -0.9326, \"times_seen\": 15.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.052963525262229416, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08427910600943868, \"functional effect\": -0.2531, \"times_seen\": 10.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.012510096355888192, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08667575148523557, \"functional effect\": -0.6761, \"times_seen\": 1.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.6473655188116079, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.027909823816916316, \"functional effect\": 0.0541, \"times_seen\": 19.0}, {\"site\": 476, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0009201036085582217, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08737487172702953, \"functional effect\": -0.0611, \"times_seen\": 14.0}, {\"site\": 477, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0037085883071009094, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": 0.08720615403076361, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 477, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 477, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.025618711352343004, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": 0.08899703345803196, \"functional effect\": -2.6892, \"times_seen\": 1.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.042064904508498056, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08491819062079392, \"functional effect\": -0.1436, \"times_seen\": 25.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.02059682638946053, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08619126751095234, \"functional effect\": -0.2157, \"times_seen\": 10.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01810376718767145, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08634033969589724, \"functional effect\": -2.158, \"times_seen\": 3.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0062227336037532785, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.0870543145864345, \"functional effect\": -0.2804, \"times_seen\": 70.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.6039575492859859, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.05752467736124454, \"functional effect\": -0.4046, \"times_seen\": 38.0}, {\"site\": 478, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03515098619543248, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08532612612105604, \"functional effect\": -0.2739, \"times_seen\": 10.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.45830003329983315, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.06363579482677094, \"functional effect\": -0.4916, \"times_seen\": 36.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.05891999647480243, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08393185925231278, \"functional effect\": -0.67, \"times_seen\": 10.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.014736282108063197, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08654210749179522, \"functional effect\": -0.9962, \"times_seen\": 8.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.010279979819810773, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08680983838327419, \"functional effect\": -0.7021, \"times_seen\": 30.0}, {\"site\": 479, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.08505860603711808, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08242488277410723, \"functional effect\": -1.8789, \"times_seen\": 17.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.07464394320604964, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.09207327601755523, \"functional effect\": -0.1605, \"times_seen\": 4.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.022149940199948686, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08878330879408552, \"functional effect\": -0.1194, \"times_seen\": 2.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.022919974773979, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08605258680086429, \"functional effect\": -0.843, \"times_seen\": 17.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.019959368401768852, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08622935972766231, \"functional effect\": -0.3308, \"times_seen\": 7.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.021909227805589706, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08876849661310068, \"functional effect\": 0.0897, \"times_seen\": 17.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.16246507992361467, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.07811899863331932, \"functional effect\": -0.1138, \"times_seen\": 31.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.001883639415925328, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.0873165359680762, \"functional effect\": 0.042, \"times_seen\": 8.0}, {\"site\": 480, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005412032456541003, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08710324721856884, \"functional effect\": -2.7147, \"times_seen\": 1.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.022948651557186624, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08883247501983413, \"functional effect\": -2.9819, \"times_seen\": 4.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.18301353307939086, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.07701422809532499, \"functional effect\": -1.4618, \"times_seen\": 36.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.1836123747684193, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09929705366738137, \"functional effect\": -0.2489, \"times_seen\": 20.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.06209025683832642, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08374762509539609, \"functional effect\": -0.8377, \"times_seen\": 14.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.24321078921463682, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.07386688536181693, \"functional effect\": -0.696, \"times_seen\": 50.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.09763956436125404, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09355262277920827, \"functional effect\": -0.6341, \"times_seen\": 14.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.043802112794686626, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08481599868274661, \"functional effect\": -0.1683, \"times_seen\": 10.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06482013244434297, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.0835893072041491, \"functional effect\": -0.3417, \"times_seen\": 18.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.09769638447605575, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.0817060071630476, \"functional effect\": -0.1515, \"times_seen\": 32.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.006230735127406482, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08705383176421229, \"functional effect\": -0.3964, \"times_seen\": 5.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.08799084949711351, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08225752628606779, \"functional effect\": -0.7223, \"times_seen\": 19.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01711521678712325, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08847401242368041, \"functional effect\": 0.0548, \"times_seen\": 56.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05556488292187639, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.0908636600330984, \"functional effect\": -0.136, \"times_seen\": 18.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.11335624576866721, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09457735412733048, \"functional effect\": -0.2489, \"times_seen\": 33.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.2765309268152394, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.07218042356984482, \"functional effect\": -0.2204, \"times_seen\": 55.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.08559227592026993, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09277466021089707, \"functional effect\": 0.0389, \"times_seen\": 84.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.010786612730311477, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08677935862257835, \"functional effect\": -0.0617, \"times_seen\": 67.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.017675600388431516, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08636596781003598, \"functional effect\": -2.5984, \"times_seen\": 4.0}, {\"site\": 481, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.015829637725602218, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.0883952087451926, \"functional effect\": -1.1779, \"times_seen\": 13.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.08295385841063045, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.0825452201847235, \"functional effect\": -0.7599, \"times_seen\": 32.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004008965723074149, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.08718799909732183, \"functional effect\": -1.7725, \"times_seen\": 1.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.5006175812824297, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.12369850142157202, \"functional effect\": -0.4621, \"times_seen\": 34.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.035093861964272326, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.08532950471855145, \"functional effect\": -1.2887, \"times_seen\": 11.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1940708948983472, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.07642621809401752, \"functional effect\": -0.1985, \"times_seen\": 40.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004640560600043482, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.08714983757336019, \"functional effect\": -0.7847, \"times_seen\": 1.0}, {\"site\": 482, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0727706362784304, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.09195379853429654, \"functional effect\": -1.5063, \"times_seen\": 11.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.10634547036591163, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.0812176377095029, \"functional effect\": 0.0929, \"times_seen\": 15.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.5333081437632887, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.03020590040426623, \"functional effect\": 0.1442, \"times_seen\": 15.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.29074256963901823, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.07147288216126436, \"functional effect\": 0.1937, \"times_seen\": 40.0}, {\"site\": 483, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05814773427157935, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.08397679927907045, \"functional effect\": -0.0454, \"times_seen\": 9.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004505049411980009, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08715802387216431, \"functional effect\": 0.3125, \"times_seen\": 1.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.013576482769595654, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08661170767193471, \"functional effect\": -2.8443, \"times_seen\": 3.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02752664186628619, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08577825065588518, \"functional effect\": -0.32, \"times_seen\": 7.0}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 484, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.015380056207502501, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.0883676667772002, \"functional effect\": -0.3665, \"times_seen\": 3.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.03532553609370634, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.0853158032425089, \"functional effect\": -2.9821, \"times_seen\": 2.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -2.4283531056823424, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.016242632008542684, \"functional effect\": -3.08, \"times_seen\": 1.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.033666311852740834, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08541398025018299, \"functional effect\": -2.961, \"times_seen\": 3.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.02529372941089987, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08591111561938011, \"functional effect\": -2.8571, \"times_seen\": 1.0}, {\"site\": 485, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04222379547399931, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08490883868574782, \"functional effect\": -2.3412, \"times_seen\": 4.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.015048833543370098, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08652336068157719, \"functional effect\": -2.3672, \"times_seen\": 1.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.07039153864216116, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.0832671241460212, \"functional effect\": -1.0498, \"times_seen\": 1.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.015225112111150735, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08651278929823204, \"functional effect\": -1.714, \"times_seen\": 1.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -1.7662151869970026, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.02570276111654696, \"functional effect\": -0.2363, \"times_seen\": 37.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014642104761412126, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08654775703785514, \"functional effect\": -0.4084, \"times_seen\": 2.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.05772785413603599, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08400124333717185, \"functional effect\": -0.3635, \"times_seen\": 4.0}, {\"site\": 486, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.013868543740223057, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08827513240187349, \"functional effect\": -0.5613, \"times_seen\": 3.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.042677857806991334, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08488211935986477, \"functional effect\": -0.6844, \"times_seen\": 10.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.007964888038533303, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08694925390379407, \"functional effect\": -2.5252, \"times_seen\": 2.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008162361298937767, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.0869373532753752, \"functional effect\": -0.2581, \"times_seen\": 6.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.014916927152174133, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08653127192109888, \"functional effect\": -0.0441, \"times_seen\": 2.0}, {\"site\": 487, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.001453968032546793, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08751877252919958, \"functional effect\": 0.0991, \"times_seen\": 11.0}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.022066306414004904, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.08610352071742716, \"functional effect\": -1.8109, \"times_seen\": 3.0}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005461225163116241, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.087100277241332, \"functional effect\": -3.0999, \"times_seen\": 1.0}, {\"site\": 488, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004399709050610103, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.08716438806741694, \"functional effect\": -2.9169, \"times_seen\": 1.0}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02507434811003163, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.0859241805602269, \"functional effect\": -2.4022, \"times_seen\": 4.0}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0008574481419761071, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.08748259309036353, \"functional effect\": -1.0383, \"times_seen\": 1.0}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 489, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.015064948244315925, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.0865223942331902, \"functional effect\": -1.8611, \"times_seen\": 2.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006481242019377435, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08703871721054247, \"functional effect\": -2.5897, \"times_seen\": 2.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.14020060371032705, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.09635363805344478, \"functional effect\": -0.3866, \"times_seen\": 45.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.029509095118098363, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08566046097468215, \"functional effect\": -2.3533, \"times_seen\": 3.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.017317530834939622, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08848642030628054, \"functional effect\": -1.5278, \"times_seen\": 7.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.20951621570906415, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.10109605190723746, \"functional effect\": -0.2944, \"times_seen\": 16.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.029894120035346364, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.0856376030522987, \"functional effect\": -2.0279, \"times_seen\": 2.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07577929939856279, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08295674206356066, \"functional effect\": -0.9766, \"times_seen\": 42.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.15909692203860443, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.07830159058335631, \"functional effect\": -0.7874, \"times_seen\": 46.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.023371868011786857, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08885853796378922, \"functional effect\": -1.119, \"times_seen\": 7.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.050336879274724196, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.09053498636323848, \"functional effect\": -0.0552, \"times_seen\": 34.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.015351920446418999, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08650518543161054, \"functional effect\": -1.6339, \"times_seen\": 30.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.04253943300611228, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.09004698482796662, \"functional effect\": -0.8017, \"times_seen\": 6.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.011297337888322547, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08811794644653796, \"functional effect\": -0.746, \"times_seen\": 5.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.014312463927743421, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08656753456088591, \"functional effect\": -2.6584, \"times_seen\": 5.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.15210501993285744, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.09715199058434944, \"functional effect\": -0.2715, \"times_seen\": 26.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01962794903055948, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08862824128639056, \"functional effect\": -0.6663, \"times_seen\": 45.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.006597527277939976, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08783135515737883, \"functional effect\": -0.8249, \"times_seen\": 22.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"V\", \"log2 fold change IC90\": 1.0437890248239758, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.18025002581036578, \"functional effect\": -0.7732, \"times_seen\": 34.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.06699106614249038, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08346361856337207, \"functional effect\": -1.7173, \"times_seen\": 2.0}, {\"site\": 490, \"wildtype\": \"R\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07449335227646647, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08303071857180604, \"functional effect\": -1.2071, \"times_seen\": 13.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.04381311879952382, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.09012651806596064, \"functional effect\": -0.1818, \"times_seen\": 3.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.029550461320853715, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.08923990621643052, \"functional effect\": -1.5274, \"times_seen\": 2.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 4.406224389807453, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 1.8538271527494408, \"functional effect\": -1.0881, \"times_seen\": 11.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.04176037669021526, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.08999837252065063, \"functional effect\": -0.5503, \"times_seen\": 23.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.005832183211625005, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.08778477332444766, \"functional effect\": -0.1058, \"times_seen\": 11.0}, {\"site\": 491, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 2.1442620106351202, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.38650108170949693, \"functional effect\": -0.9805, \"times_seen\": 5.0}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0065611739603546005, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.08703389499885984, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.009199271713974584, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.08798989241427173, \"functional effect\": -2.3786, \"times_seen\": 8.0}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.002908786734395637, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.08725451279965718, \"functional effect\": -2.1345, \"times_seen\": 1.0}, {\"site\": 492, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.002710244453790375, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08726652150667011, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.16710438779007114, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.07786819303641465, \"functional effect\": 0.0471, \"times_seen\": 44.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.047434606825993146, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08460271308990046, \"functional effect\": -1.1981, \"times_seen\": 31.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.1340218446792923, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.07967442439997263, \"functional effect\": 0.2573, \"times_seen\": 29.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.13338700229069048, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.09589964923418152, \"functional effect\": 0.4075, \"times_seen\": 3.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.1257114096687177, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.09539078770715445, \"functional effect\": -0.6332, \"times_seen\": 19.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.6012482662556888, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.057632806285141024, \"functional effect\": 0.0404, \"times_seen\": 50.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.09306327049329699, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.09325633979186639, \"functional effect\": -0.0759, \"times_seen\": 23.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.023619643387132065, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08887380026644487, \"functional effect\": -0.1474, \"times_seen\": 33.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 3.365701123660225, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.9012401363903169, \"functional effect\": -0.6137, \"times_seen\": 7.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.5109767324259695, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.12458990466413729, \"functional effect\": -0.5501, \"times_seen\": 34.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.9291848139464888, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.04591462371109743, \"functional effect\": -0.1907, \"times_seen\": 7.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 2.0486841179734, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.36172531300403105, \"functional effect\": 0.1379, \"times_seen\": 47.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.008333326913770941, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08793709433480953, \"functional effect\": -2.2628, \"times_seen\": 13.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01569462022409469, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08648463931045525, \"functional effect\": 0.0007, \"times_seen\": 5.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 2.5007832960336924, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.4948508433218117, \"functional effect\": -1.4775, \"times_seen\": 39.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -1.3790774689181853, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.03361397289005698, \"functional effect\": 0.0331, \"times_seen\": 36.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.3055280730702532, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.07074413087630493, \"functional effect\": -0.1352, \"times_seen\": 46.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.03147710844960017, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08554368924252852, \"functional effect\": -1.3651, \"times_seen\": 7.0}, {\"site\": 493, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 2.0600365341866644, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.36458291997598113, \"functional effect\": -0.4377, \"times_seen\": 12.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008643422395315082, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.08690836918286046, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004018107496962867, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.08718744662405085, \"functional effect\": -2.6818, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.13270199459747414, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.07974734792802664, \"functional effect\": -2.4924, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008741382059058793, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.0869024682645436, \"functional effect\": -2.9094, \"times_seen\": 1.0}, {\"site\": 494, \"wildtype\": \"F\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0337091170432308, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.08949751675472428, \"functional effect\": -0.8619, \"times_seen\": 6.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.03501721553907133, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08957870138103019, \"functional effect\": -2.4975, \"times_seen\": 2.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.003353646874210361, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08722761170847404, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01725137098375675, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08639136775216287, \"functional effect\": -0.043, \"times_seen\": 5.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00600653067692431, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08706736156270821, \"functional effect\": -2.4122, \"times_seen\": 1.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.024929147074783352, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08895450575163463, \"functional effect\": -0.7782, \"times_seen\": 2.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.022546097690575157, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08880769163406604, \"functional effect\": -0.2172, \"times_seen\": 9.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.003468932866957028, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08764109252792217, \"functional effect\": -0.0421, \"times_seen\": 11.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.13174936055121822, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.0798000237355976, \"functional effect\": -0.3789, \"times_seen\": 28.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.041641758180940826, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08494310100697881, \"functional effect\": -0.2841, \"times_seen\": 10.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04160891728327672, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08494503463769032, \"functional effect\": -0.1404, \"times_seen\": 9.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.04639091427425552, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08466393959028624, \"functional effect\": 0.1592, \"times_seen\": 24.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009539113512585934, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08685442923517753, \"functional effect\": -0.3126, \"times_seen\": 16.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.09638715033051748, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08178018836168952, \"functional effect\": -0.1347, \"times_seen\": 15.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.007985974711105239, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08791592460335303, \"functional effect\": -0.0844, \"times_seen\": 5.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.002040507352328703, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08730704233304866, \"functional effect\": -2.7657, \"times_seen\": 1.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.024418291946506885, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08892301273370692, \"functional effect\": 0.0442, \"times_seen\": 8.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.09279261577720975, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08198420114175287, \"functional effect\": 0.0007, \"times_seen\": 13.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05010896289378094, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08444602841804354, \"functional effect\": -0.1952, \"times_seen\": 12.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.04503496622986628, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08474355022562527, \"functional effect\": -0.2869, \"times_seen\": 12.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": 7.231869379216316, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 13.142353296202755, \"functional effect\": -0.8692, \"times_seen\": 9.0}, {\"site\": 495, \"wildtype\": \"R\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.016636641742205138, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08642818677110278, \"functional effect\": -0.0976, \"times_seen\": 7.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.2259231433818354, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 0.10225232055290243, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 6.581809701097754, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 8.37501658507645, \"functional effect\": -0.4608, \"times_seen\": 4.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.26075372665423713, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 0.10475101098374653, \"functional effect\": -1.8239, \"times_seen\": 3.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 6.44314440530769, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 7.607522795218833, \"functional effect\": -0.5042, \"times_seen\": 2.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 3.567840837831147, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 1.0367896232725338, \"functional effect\": -2.0994, \"times_seen\": 6.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 8.933908215344843, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 42.76001819051696, \"functional effect\": -0.0307, \"times_seen\": 10.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 8.67228369249101, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 35.668188431413775, \"functional effect\": -0.3631, \"times_seen\": 3.0}, {\"site\": 496, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": 7.638632659461798, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 17.42292576976448, \"functional effect\": -2.3457, \"times_seen\": 2.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.09619600709996388, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.0934590610617352, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 5.612560028148913, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 4.277720952138734, \"functional effect\": -0.5078, \"times_seen\": 13.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04501288759610761, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.09020149992648434, \"functional effect\": -1.0395, \"times_seen\": 5.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 1.9226094570405352, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.33145658116387416, \"functional effect\": 0.2023, \"times_seen\": 4.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 3.76140396493588, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 1.1856566711391079, \"functional effect\": 0.006, \"times_seen\": 13.0}, {\"site\": 497, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.02350477135624861, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08886672412962518, \"functional effect\": -2.8664, \"times_seen\": 3.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.07553597101534433, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.09213022313178199, \"functional effect\": 0.1028, \"times_seen\": 31.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00837091388369345, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08692478672541229, \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.037258272389261174, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08520158468417229, \"functional effect\": 0.1304, \"times_seen\": 9.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.20846999404555944, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.07566722526152218, \"functional effect\": 0.0618, \"times_seen\": 26.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.05565890933367512, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08412179453333164, \"functional effect\": -0.0232, \"times_seen\": 28.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.08981894146186885, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08215336075808381, \"functional effect\": 0.0356, \"times_seen\": 17.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.07269293353117398, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08313440186950606, \"functional effect\": 0.0028, \"times_seen\": 26.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.947118330586841, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.3371355519429607, \"functional effect\": -0.3911, \"times_seen\": 48.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.016947661653891073, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08846373761597395, \"functional effect\": -2.849, \"times_seen\": 3.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0569938919106829, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.0909537063083737, \"functional effect\": 0.1459, \"times_seen\": 48.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.013151840979665732, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08823128992860182, \"functional effect\": 0.1332, \"times_seen\": 14.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.4386010043113103, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.06451065798133478, \"functional effect\": 0.0985, \"times_seen\": 64.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.014029743338473772, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08828499637901015, \"functional effect\": -2.004, \"times_seen\": 8.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.34283843129411967, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.06893803155485291, \"functional effect\": -0.1512, \"times_seen\": 11.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02052108851481608, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08619579245529782, \"functional effect\": -2.9894, \"times_seen\": 7.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.22436190341069037, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.07483829198515227, \"functional effect\": 0.0133, \"times_seen\": 73.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.41202597834634963, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.06570998249373705, \"functional effect\": -0.047, \"times_seen\": 50.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.05230595027138823, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.09065863794756965, \"functional effect\": -0.0001, \"times_seen\": 47.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"W\", \"log2 fold change IC90\": 2.6151183687657853, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.5356641740933674, \"functional effect\": -0.376, \"times_seen\": 27.0}, {\"site\": 498, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0005544410174460102, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.08739702039350893, \"functional effect\": -3.0563, \"times_seen\": 1.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015540651050038977, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.08649386972900736, \"functional effect\": -2.6212, \"times_seen\": 1.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.05694646892716446, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.09095071660847016, \"functional effect\": -2.936, \"times_seen\": 2.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04225241231492903, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.08490715447767688, \"functional effect\": -0.1043, \"times_seen\": 7.0}, {\"site\": 499, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.02659370540967499, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.0890571992613572, \"functional effect\": -2.1212, \"times_seen\": 1.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0028344795568460593, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08725900702980713, \"functional effect\": 0.0538, \"times_seen\": 10.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0053938272674663385, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.0871043463705343, \"functional effect\": 0.3375, \"times_seen\": 1.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.05388551843495474, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08422526238083411, \"functional effect\": -0.1554, \"times_seen\": 12.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.010606907579544439, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08679016871658807, \"functional effect\": -0.7935, \"times_seen\": 8.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.00980347073128821, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08802675019707684, \"functional effect\": 0.1889, \"times_seen\": 10.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.006554173701285989, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08782871582885267, \"functional effect\": -0.1482, \"times_seen\": 16.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.025013700182190637, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08592779271171332, \"functional effect\": -0.1088, \"times_seen\": 8.0}, {\"site\": 500, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.035511844131828944, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.0896094187413575, \"functional effect\": -2.5791, \"times_seen\": 1.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.48711135017053214, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.06237756283180639, \"functional effect\": -0.2888, \"times_seen\": 82.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 2.0787508787365305, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.36934302171805933, \"functional effect\": -0.2675, \"times_seen\": 5.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.06267694569322971, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.09131269708759605, \"functional effect\": -0.7602, \"times_seen\": 2.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05055668076175124, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.08441982597832004, \"functional effect\": -0.1053, \"times_seen\": 34.0}, {\"site\": 501, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0034674505948874184, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.08764100248264359, \"functional effect\": -0.6904, \"times_seen\": 12.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.8460623291448287, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.15716421556477989, \"functional effect\": -0.0962, \"times_seen\": 17.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.007947053295095187, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08695032878599486, \"functional effect\": -2.6374, \"times_seen\": 3.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.26321512509812783, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.07284971917961597, \"functional effect\": 0.2021, \"times_seen\": 20.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005943785972575167, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08707114831909364, \"functional effect\": 0.1255, \"times_seen\": 4.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"F\", \"log2 fold change IC90\": -4.097430240616375, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.005107567588847657, \"functional effect\": -0.1583, \"times_seen\": 17.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.09653685267142101, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08177170281891954, \"functional effect\": -0.7695, \"times_seen\": 9.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00811596468748435, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08694014919783054, \"functional effect\": -1.8906, \"times_seen\": 1.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.03529308543883621, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.085317722279273, \"functional effect\": -0.9618, \"times_seen\": 6.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.12106130944105038, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08039340893362289, \"functional effect\": -0.0845, \"times_seen\": 39.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.04653842887944826, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08465528320152355, \"functional effect\": 0.2724, \"times_seen\": 6.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0735031727678538, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08308772544718557, \"functional effect\": -0.1694, \"times_seen\": 24.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0029505226256476545, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08725198864030266, \"functional effect\": -2.9748, \"times_seen\": 11.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08665747120789095, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08233358608872794, \"functional effect\": -0.0357, \"times_seen\": 27.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.2409871164476039, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.07398082658165604, \"functional effect\": -1.0928, \"times_seen\": 58.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07079330473648746, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08324393889302908, \"functional effect\": -0.3556, \"times_seen\": 23.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06606503570750953, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08351720900303301, \"functional effect\": -1.0339, \"times_seen\": 10.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03130986642421561, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08555360632736138, \"functional effect\": -1.2803, \"times_seen\": 6.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.004441530346371038, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08716186135545466, \"functional effect\": -0.1674, \"times_seen\": 7.0}, {\"site\": 502, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.6135148789890339, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.057144856780440456, \"functional effect\": -0.1237, \"times_seen\": 40.0}, {\"site\": 503, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0004897558104497922, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": 0.0874009390464004, \"functional effect\": -3.1158, \"times_seen\": 1.0}, {\"site\": 503, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 503, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0016414848111775354, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": 0.08733119317230931, \"functional effect\": -2.8214, \"times_seen\": 1.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.008943445551967676, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.0868902975797294, \"functional effect\": -1.0223, \"times_seen\": 3.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.003382155964123229, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.08722588802108056, \"functional effect\": -2.8046, \"times_seen\": 1.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03857627604683086, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.08979996061113762, \"functional effect\": -2.3546, \"times_seen\": 2.0}, {\"site\": 504, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.002627486638482177, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.0872715275499484, \"functional effect\": -1.6578, \"times_seen\": 1.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.008591095585933444, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08691152142225397, \"functional effect\": -1.0566, \"times_seen\": 1.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.039379286243839955, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08507641549656661, \"functional effect\": -0.9961, \"times_seen\": 5.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.004930950418772795, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08713229756801387, \"functional effect\": 0.0169, \"times_seen\": 1.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.009995543362938595, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08803847038368962, \"functional effect\": 0.1304, \"times_seen\": 11.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0047199041322895366, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08714504474770392, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 505, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.012891367105925014, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.08665284812627227, \"functional effect\": -2.951, \"times_seen\": 1.0}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.04543626022744993, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.09022797430206705, \"functional effect\": -1.815, \"times_seen\": 2.0}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0009562841977152711, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.08737268052611223, \"functional effect\": -2.8316, \"times_seen\": 1.0}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 506, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0043013124092572425, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.08717033317381452, \"functional effect\": -2.9775, \"times_seen\": 1.0}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.025615359131572285, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.08589196501061017, \"functional effect\": -0.8584, \"times_seen\": 4.0}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07852642149546882, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.08279892945679684, \"functional effect\": -2.6987, \"times_seen\": 5.0}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.006053827606979665, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.08706450721629962, \"functional effect\": -1.5842, \"times_seen\": 1.0}, {\"site\": 507, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02646462597751498, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.08904923157716554, \"functional effect\": -1.2286, \"times_seen\": 3.0}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03148643770812138, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.08935973911057714, \"functional effect\": -1.83, \"times_seen\": 2.0}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0037465490015537897, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.08720385946224991, \"functional effect\": -1.3902, \"times_seen\": 7.0}, {\"site\": 508, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 509, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011142937570788288, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": 0.08675792802085272, \"functional effect\": -1.3994, \"times_seen\": 4.0}, {\"site\": 509, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004601189786652029, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": 0.08715221590468673, \"functional effect\": -2.8254, \"times_seen\": 1.0}, {\"site\": 509, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.042774769476315096, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.0848764176756094, \"functional effect\": -0.3652, \"times_seen\": 11.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009446031775744795, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08686003320670811, \"functional effect\": -1.4701, \"times_seen\": 2.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.025395437662564642, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08590505920335094, \"functional effect\": -0.38, \"times_seen\": 9.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01641893559015506, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08644122997648895, \"functional effect\": -2.8942, \"times_seen\": 5.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005338569043739345, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08710768271224373, \"functional effect\": -0.8287, \"times_seen\": 1.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005112343550408586, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08712134292666182, \"functional effect\": -2.4129, \"times_seen\": 1.0}, {\"site\": 510, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.035511101121113636, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.0853048302989559, \"functional effect\": -1.5414, \"times_seen\": 4.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.006002445097203664, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08706760812982069, \"functional effect\": -0.8028, \"times_seen\": 1.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.060383131827955974, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08384678138324837, \"functional effect\": -1.7083, \"times_seen\": 15.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.021621908879280307, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08875081974523841, \"functional effect\": 0.0622, \"times_seen\": 10.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.034064424329047605, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08539041346794958, \"functional effect\": -0.1658, \"times_seen\": 24.0}, {\"site\": 511, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0514265856510923, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08436893852016258, \"functional effect\": -1.2422, \"times_seen\": 23.0}, {\"site\": 512, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 512, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.006692651762071626, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": 0.08702596365962349, \"functional effect\": -0.3377, \"times_seen\": 12.0}, {\"site\": 512, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.011027438424071185, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": 0.08810146287839613, \"functional effect\": -2.6288, \"times_seen\": 5.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.023671322457249726, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08887698388979443, \"functional effect\": -1.7671, \"times_seen\": 1.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -3.717001228638076e-05, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08742836177114865, \"functional effect\": -0.8865, \"times_seen\": 1.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03814271567883462, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08514936791350747, \"functional effect\": -0.6653, \"times_seen\": 5.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.014346472317190046, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08656549394409153, \"functional effect\": -1.2325, \"times_seen\": 26.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010168092727507086, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08804900059982308, \"functional effect\": -0.1296, \"times_seen\": 20.0}, {\"site\": 513, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0032100163831887806, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08723629626620698, \"functional effect\": -0.5221, \"times_seen\": 3.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.025931849732183435, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08587312456456823, \"functional effect\": 0.1757, \"times_seen\": 29.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.012059146672133874, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.086702848349754, \"functional effect\": -0.6957, \"times_seen\": 12.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.11388189351435374, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.09461181978322299, \"functional effect\": 0.1283, \"times_seen\": 32.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.007325417473983486, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.086987802461409, \"functional effect\": -0.1504, \"times_seen\": 3.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 2.449039671772241, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.47741705750338065, \"functional effect\": -1.4089, \"times_seen\": 2.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.026276056916502238, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08903759305887138, \"functional effect\": -1.2135, \"times_seen\": 2.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0041984447352485296, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08717654885270328, \"functional effect\": -2.1178, \"times_seen\": 5.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.029349907190493622, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08566991332823587, \"functional effect\": -0.8606, \"times_seen\": 8.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.06844869655509792, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08337933348113065, \"functional effect\": -0.0136, \"times_seen\": 66.0}, {\"site\": 514, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012851007343602438, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08665527229574334, \"functional effect\": -0.9741, \"times_seen\": 7.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0847834107066142, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08244060689164205, \"functional effect\": 0.19, \"times_seen\": 20.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.029469579274327622, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08566280727217054, \"functional effect\": 0.1959, \"times_seen\": 22.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.010509090986000804, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08679605340200182, \"functional effect\": -0.124, \"times_seen\": 7.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.04047802373160561, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08501164708874152, \"functional effect\": -0.3749, \"times_seen\": 14.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012430000781991626, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08668056368502661, \"functional effect\": -0.5652, \"times_seen\": 10.0}, {\"site\": 515, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.008216782811832404, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08792999086841036, \"functional effect\": 0.0737, \"times_seen\": 5.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06669248433624168, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08348089407640033, \"functional effect\": -0.6861, \"times_seen\": 35.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.06320483939065706, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.0913461152501335, \"functional effect\": -0.7408, \"times_seen\": 21.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.04957061141008806, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08447754590900211, \"functional effect\": -0.1239, \"times_seen\": 21.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08408966746338507, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08248025932377673, \"functional effect\": -0.0534, \"times_seen\": 14.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.031301886785211175, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08555407953116584, \"functional effect\": -1.268, \"times_seen\": 9.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.024229115640870734, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08891135328823248, \"functional effect\": -0.6903, \"times_seen\": 1.0}, {\"site\": 516, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02311264209916712, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08604109551945505, \"functional effect\": 0.0498, \"times_seen\": 34.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.006680797452604374, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08783642479659608, \"functional effect\": -0.6494, \"times_seen\": 4.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.011018713619971112, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08810093007994706, \"functional effect\": -0.226, \"times_seen\": 9.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.9190782696950534, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.046237399719725215, \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03169747831318332, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08553062354886817, \"functional effect\": -1.6363, \"times_seen\": 9.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.10013181216551911, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08156819480258974, \"functional effect\": -0.13, \"times_seen\": 60.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.3903051665482156, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.11459273701637869, \"functional effect\": -1.255, \"times_seen\": 30.0}, {\"site\": 517, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.009275493146975778, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08687030139650727, \"functional effect\": -1.6988, \"times_seen\": 20.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0026129148692966312, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08727240903005488, \"functional effect\": -1.0538, \"times_seen\": 1.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0004935013040558816, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08740071213827072, \"functional effect\": -0.0597, \"times_seen\": 2.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.03839456454122175, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08978865076532981, \"functional effect\": -1.6256, \"times_seen\": 13.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.053434827120225216, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.09072960408068366, \"functional effect\": -0.2545, \"times_seen\": 18.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.06509278578667567, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08357351124598165, \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02714036750262564, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08909095096796679, \"functional effect\": -0.4019, \"times_seen\": 17.0}, {\"site\": 518, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06018754590495702, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08385814924778975, \"functional effect\": -0.3776, \"times_seen\": 22.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005165905848506948, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08711810847129506, \"functional effect\": -1.9549, \"times_seen\": 1.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.028344861386828173, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08572961560954272, \"functional effect\": -0.781, \"times_seen\": 25.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.17209039054122113, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.09850718293389668, \"functional effect\": -1.3558, \"times_seen\": 33.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.04104084880352536, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08497848876126747, \"functional effect\": -1.3925, \"times_seen\": 15.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.019531748387514477, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08625492220915355, \"functional effect\": -0.6136, \"times_seen\": 27.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.08996043745694225, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.09305598704801617, \"functional effect\": -0.8527, \"times_seen\": 45.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.019695787988781913, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08624511527264422, \"functional effect\": -1.3548, \"times_seen\": 5.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0005451686058267909, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08739758210872152, \"functional effect\": -1.092, \"times_seen\": 12.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.005559378886297707, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08709435157759655, \"functional effect\": -2.5438, \"times_seen\": 1.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04581194753064318, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08469792282370665, \"functional effect\": -1.747, \"times_seen\": 34.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03799419080071073, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08976373626215588, \"functional effect\": -0.3471, \"times_seen\": 9.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.05036982954698001, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08443076035330319, \"functional effect\": -1.8793, \"times_seen\": 6.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.07494745771260963, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.0920926484517496, \"functional effect\": 0.1483, \"times_seen\": 44.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01358228361869278, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08661135942062592, \"functional effect\": -1.8429, \"times_seen\": 3.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04836116904965537, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08454839495024817, \"functional effect\": -2.3261, \"times_seen\": 17.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.010744355065617966, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08678190049500571, \"functional effect\": -0.2522, \"times_seen\": 76.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.07547261646760924, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08297437858437165, \"functional effect\": -1.2783, \"times_seen\": 67.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.7028997685048761, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.05371178873542836, \"functional effect\": -0.2323, \"times_seen\": 116.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.012695802249427205, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08666459516910326, \"functional effect\": -1.3283, \"times_seen\": 3.0}, {\"site\": 519, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05836975944143986, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08396387656985213, \"functional effect\": 0.0691, \"times_seen\": 15.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.2518433890278598, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.07342621060972877, \"functional effect\": -0.4663, \"times_seen\": 46.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.032369366707326735, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.0854907997108066, \"functional effect\": -1.99, \"times_seen\": 17.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.005375363985574574, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.08710546111921395, \"functional effect\": -2.2485, \"times_seen\": 1.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.19491302347491105, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.10007790296750103, \"functional effect\": -0.7974, \"times_seen\": 28.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.005487286479220634, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.08709870384758542, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05982460393917897, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.08387924828076172, \"functional effect\": 0.2301, \"times_seen\": 14.0}, {\"site\": 520, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 521, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004920584588595423, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": 0.08713292361982573, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 521, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.00541369958969871, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": 0.08710314656484539, \"functional effect\": -2.1667, \"times_seen\": 1.0}, {\"site\": 521, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 522, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 522, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.004661862619627545, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": 0.08714855077761444, \"functional effect\": -0.9191, \"times_seen\": 1.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.004028276212068427, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.08718683209280491, \"functional effect\": -2.1818, \"times_seen\": 1.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004142421218062005, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.0871799342055142, \"functional effect\": -0.6305, \"times_seen\": 2.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.002702423740042526, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.0872669945715348, \"functional effect\": -1.0706, \"times_seen\": 2.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.012325119644006342, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.0866868654233466, \"functional effect\": -0.6872, \"times_seen\": 3.0}, {\"site\": 523, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004712656750163993, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.0871454825221525, \"functional effect\": -2.7353, \"times_seen\": 1.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.017328378049298723, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.08638675654329281, \"functional effect\": -0.785, \"times_seen\": 2.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.1477643778338595, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.03945954055662785, \"functional effect\": -2.6974, \"times_seen\": 2.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03376711189867618, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.08540801264641514, \"functional effect\": -1.9063, \"times_seen\": 5.0}, {\"site\": 524, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0061397099191612264, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.08780348763275236, \"functional effect\": -1.7467, \"times_seen\": 3.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.07609493230851545, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08293859476762538, \"functional effect\": -0.5715, \"times_seen\": 16.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.052726886827643135, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08429293104582675, \"functional effect\": 0.0142, \"times_seen\": 16.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0059521917253736204, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.0870706410071561, \"functional effect\": -2.2802, \"times_seen\": 1.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.043988461308729375, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.0848050439666395, \"functional effect\": -0.0454, \"times_seen\": 10.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.027099175939194718, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08580367024293366, \"functional effect\": -0.3537, \"times_seen\": 5.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.011080702259823457, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08676167068505972, \"functional effect\": -0.0315, \"times_seen\": 2.0}, {\"site\": 525, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.01646564648715113, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08643843126857786, \"functional effect\": -0.7099, \"times_seen\": 4.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.049545198744419046, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08447903397021923, \"functional effect\": -0.2878, \"times_seen\": 11.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.007063251021349141, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.0870036113157824, \"functional effect\": -0.6437, \"times_seen\": 2.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.007019218624558704, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08700626678758355, \"functional effect\": -0.2172, \"times_seen\": 5.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.04190804145037386, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.084927424208548, \"functional effect\": -0.3064, \"times_seen\": 11.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.000908410205582707, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08737557992501781, \"functional effect\": -0.3323, \"times_seen\": 17.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.009615309087507663, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08801527017013387, \"functional effect\": -0.2839, \"times_seen\": 11.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.7774556655163206, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.1498652717670619, \"functional effect\": -0.3896, \"times_seen\": 37.0}, {\"site\": 526, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.014083028614532627, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08658130270193437, \"functional effect\": -0.0142, \"times_seen\": 7.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0215641331989446, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08613349684319739, \"functional effect\": -1.2372, \"times_seen\": 4.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.010510212842945439, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08679598590837728, \"functional effect\": -0.6498, \"times_seen\": 2.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.11931457008065523, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08049080399803347, \"functional effect\": -1.1321, \"times_seen\": 21.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0172342609293825, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08639239234136792, \"functional effect\": -0.5927, \"times_seen\": 6.0}, {\"site\": 527, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.006349056999363026, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08704669238293963, \"functional effect\": -2.5076, \"times_seen\": 1.0}, {\"site\": 528, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0230107757378683, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": 0.08883630033522896, \"functional effect\": -2.6095, \"times_seen\": 2.0}, {\"site\": 528, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.029023238033216728, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": 0.08920730004567314, \"functional effect\": -2.8056, \"times_seen\": 1.0}, {\"site\": 528, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0005415735264056983, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08746344108335469, \"functional effect\": 0.1006, \"times_seen\": 10.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.014877487826086576, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08833688892078186, \"functional effect\": 0.1214, \"times_seen\": 3.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.01604340292721066, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08840830729967296, \"functional effect\": -1.0965, \"times_seen\": 6.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012025795761940648, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08670485269041507, \"functional effect\": -0.0009, \"times_seen\": 11.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.07645426356717704, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.09218888378165162, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.038535960204855536, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08512616137383859, \"functional effect\": -0.0208, \"times_seen\": 22.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.002428830456125385, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08728354548977056, \"functional effect\": -0.3049, \"times_seen\": 1.0}, {\"site\": 529, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.021029896094800958, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08616539840908138, \"functional effect\": -0.1035, \"times_seen\": 5.0}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.006387206611335252, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.08704439061192239, \"functional effect\": -2.0848, \"times_seen\": 2.0}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0645245744080087, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.09142971422248146, \"functional effect\": -1.0553, \"times_seen\": 6.0}, {\"site\": 530, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.06027531111490298, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.09116081654931302, \"functional effect\": -1.1578, \"times_seen\": 7.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.041974547309959, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.0900117339292973, \"functional effect\": -1.5204, \"times_seen\": 9.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.022689488403804494, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.08606633574450348, \"functional effect\": -2.7729, \"times_seen\": 6.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.05372509370515288, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.08423462857801915, \"functional effect\": -0.0695, \"times_seen\": 28.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.024923855786403232, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.08593314406511149, \"functional effect\": -0.7782, \"times_seen\": 8.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.015946731473366303, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.08646952742273988, \"functional effect\": -1.2792, \"times_seen\": 5.0}, {\"site\": 531, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.003854104595691669, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.08719735849493686, \"functional effect\": -1.3257, \"times_seen\": 1.0}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03880748695057569, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.08511014145699387, \"functional effect\": -0.6013, \"times_seen\": 12.0}, {\"site\": 532, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07627597536041525, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.09217749178628402, \"functional effect\": -0.4288, \"times_seen\": 6.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.07332656560728214, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08309789723335, \"functional effect\": -0.1753, \"times_seen\": 17.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.09126607027023446, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.0820709962349594, \"functional effect\": -0.5918, \"times_seen\": 18.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014523898654950495, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08655484855215087, \"functional effect\": -1.124, \"times_seen\": 3.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04907747327355454, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.0845064267321141, \"functional effect\": -0.7847, \"times_seen\": 8.0}, {\"site\": 533, \"wildtype\": \"N\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.003714663369115594, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08720578681408693, \"functional effect\": -0.9078, \"times_seen\": 1.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02337108857770831, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.0860256833735408, \"functional effect\": -0.9206, \"times_seen\": 5.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03163087481745422, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08553457224894434, \"functional effect\": -2.6262, \"times_seen\": 1.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013564222433400186, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08661244372018921, \"functional effect\": -1.5978, \"times_seen\": 5.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0004132380105611637, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08745566108392423, \"functional effect\": -2.6023, \"times_seen\": 5.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004182692853700251, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08717750068391428, \"functional effect\": -0.5799, \"times_seen\": 2.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01288970675386685, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08665294785234982, \"functional effect\": -0.2885, \"times_seen\": 3.0}, {\"site\": 534, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.003911150059658785, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08719391070085016, \"functional effect\": -0.2944, \"times_seen\": 3.0}, {\"site\": 535, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 535, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.005032334873006048, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": 0.08712617461770557, \"functional effect\": -2.9432, \"times_seen\": 1.0}, {\"site\": 535, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004512004892018752, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": 0.08715760366940717, \"functional effect\": -2.6424, \"times_seen\": 1.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004921744647561958, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.08713285355700177, \"functional effect\": -2.5994, \"times_seen\": 1.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005031276386192781, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.08712623854108378, \"functional effect\": -2.9985, \"times_seen\": 1.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02926705660959982, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.0856748332910084, \"functional effect\": -0.192, \"times_seen\": 11.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004707292474808786, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.08714580654990614, \"functional effect\": -1.9369, \"times_seen\": 1.0}, {\"site\": 536, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0003344486573317054, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08745088503172675, \"functional effect\": -0.2562, \"times_seen\": 16.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0033080858351142413, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.0876313219087692, \"functional effect\": -0.395, \"times_seen\": 1.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005198997560668146, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08711611022896033, \"functional effect\": -1.0693, \"times_seen\": 1.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.017900466415103542, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08635250740569715, \"functional effect\": -0.1286, \"times_seen\": 11.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03472348480471832, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08956046513661972, \"functional effect\": -0.6167, \"times_seen\": 7.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.16007578959093446, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.07824848102964092, \"functional effect\": -0.1715, \"times_seen\": 32.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0831483097241201, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.09261763035705449, \"functional effect\": -0.232, \"times_seen\": 10.0}, {\"site\": 537, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04073285226592591, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08499663249474623, \"functional effect\": -0.5861, \"times_seen\": 14.0}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.033293676020253744, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.08947174860135162, \"functional effect\": -3.1258, \"times_seen\": 1.0}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.7259052425575334, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.28920964851170616, \"functional effect\": -2.8348, \"times_seen\": 2.0}, {\"site\": 538, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0322358531471562, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.08940616954982929, \"functional effect\": 0.0416, \"times_seen\": 1.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.05218537903063811, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.09065106159400863, \"functional effect\": -0.5205, \"times_seen\": 10.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0007712236680142253, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.08738388890430256, \"functional effect\": -2.7926, \"times_seen\": 1.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.027664601612346948, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.08912332995355372, \"functional effect\": -2.9886, \"times_seen\": 1.0}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 539, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.13228311477674795, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.09582629905826265, \"functional effect\": -2.3102, \"times_seen\": 2.0}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02402178345095629, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.08598689218899276, \"functional effect\": -1.8554, \"times_seen\": 6.0}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0013177049921078946, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.08735079485549183, \"functional effect\": -2.9328, \"times_seen\": 1.0}, {\"site\": 540, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0014852392482929985, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.08752066956772905, \"functional effect\": -0.5522, \"times_seen\": 1.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.04129095108400624, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08996909352068715, \"functional effect\": -0.7887, \"times_seen\": 1.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0228809594225017, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08882830704349656, \"functional effect\": -0.1076, \"times_seen\": 2.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01933172847499753, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08626688169993015, \"functional effect\": -2.0814, \"times_seen\": 2.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.024831618862931854, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08593863827004719, \"functional effect\": 0.329, \"times_seen\": 8.0}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 541, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06740736421891941, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08343953812342209, \"functional effect\": 0.3651, \"times_seen\": 10.0}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.014572935746635653, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.0883182430233279, \"functional effect\": -1.8548, \"times_seen\": 2.0}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005131743813736793, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.08712017139312055, \"functional effect\": -2.745, \"times_seen\": 1.0}, {\"site\": 542, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0036351606314563474, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.08721059260438213, \"functional effect\": -2.9644, \"times_seen\": 1.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.021314984821115518, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08614837308075893, \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.028823897904931933, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08919497494185084, \"functional effect\": 0.2297, \"times_seen\": 4.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0021940532686567384, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08729775074606616, \"functional effect\": -0.6673, \"times_seen\": 3.0}, {\"site\": 543, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003216947467014508, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08723587716125929, \"functional effect\": -0.3809, \"times_seen\": 5.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.01676059784052877, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08642076119585337, \"functional effect\": -2.6006, \"times_seen\": 4.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.08693644907089416, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.0823176665585572, \"functional effect\": -0.3784, \"times_seen\": 19.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.011812036890459562, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08671770038452789, \"functional effect\": -0.4923, \"times_seen\": 2.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.04657272086987801, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08465327102044708, \"functional effect\": -1.4994, \"times_seen\": 26.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.017774477086769925, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08636004882586006, \"functional effect\": -0.7061, \"times_seen\": 4.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.05298638195534637, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08427777078172378, \"functional effect\": -0.9731, \"times_seen\": 10.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.18935417357904313, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.07667649350223713, \"functional effect\": -0.5209, \"times_seen\": 11.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.4692388540514316, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.03157755964300898, \"functional effect\": -0.2457, \"times_seen\": 27.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08834963372876538, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08223707218241265, \"functional effect\": -0.8051, \"times_seen\": 18.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.5746882614988511, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.05870365270400627, \"functional effect\": -0.3205, \"times_seen\": 18.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 1.0748955620138594, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.18417867162754084, \"functional effect\": -1.3329, \"times_seen\": 20.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.027656664891341824, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08577052023140597, \"functional effect\": -2.1393, \"times_seen\": 6.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03627827500815034, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08525948028445252, \"functional effect\": -0.1241, \"times_seen\": 10.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.024422449594461916, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08596301517276156, \"functional effect\": 0.0268, \"times_seen\": 42.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.039138268767326914, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08509062959952564, \"functional effect\": -0.3465, \"times_seen\": 18.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.07862075879933145, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08279351544193457, \"functional effect\": -0.3819, \"times_seen\": 29.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05274824229180779, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08429168331065455, \"functional effect\": -0.4142, \"times_seen\": 13.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.018277438638891298, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08632994668201292, \"functional effect\": -1.8383, \"times_seen\": 4.0}, {\"site\": 544, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": -1.3058015372639193, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.03536536126549319, \"functional effect\": -1.3953, \"times_seen\": 5.0}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01906595077080687, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.08628277551335695, \"functional effect\": -2.5715, \"times_seen\": 4.0}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005714689522186286, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.08708497610275681, \"functional effect\": -2.5343, \"times_seen\": 1.0}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.016373364659751487, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.08842852965685558, \"functional effect\": -2.9045, \"times_seen\": 2.0}, {\"site\": 545, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.7870301278476816, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.150863161969549, \"functional effect\": -0.425, \"times_seen\": 31.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07321023980477771, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08310459776189211, \"functional effect\": -0.1083, \"times_seen\": 43.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01737190914805032, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08638414999541533, \"functional effect\": -0.3882, \"times_seen\": 9.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01205566627521121, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08670305751432587, \"functional effect\": -2.7505, \"times_seen\": 2.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.019849504772518105, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08623592648699714, \"functional effect\": -0.6592, \"times_seen\": 10.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.011483752360733568, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08812933313695434, \"functional effect\": -0.4187, \"times_seen\": 2.0}, {\"site\": 546, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.025550563623394598, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08899282965729752, \"functional effect\": -2.8942, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0034481610408897303, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08722189742045414, \"functional effect\": -0.8664, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.004258620900622042, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08717291271279391, \"functional effect\": -1.8394, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0013897078371088193, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08734643541110688, \"functional effect\": -2.7216, \"times_seen\": 1.0}, {\"site\": 547, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0007615886423444733, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08747678052515427, \"functional effect\": -2.4634, \"times_seen\": 1.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.010934480014736172, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.0867704647328989, \"functional effect\": -1.1944, \"times_seen\": 3.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.025527256492591972, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.0889913919655413, \"functional effect\": -0.3624, \"times_seen\": 8.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0395595586819883, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08986118549697118, \"functional effect\": -1.7071, \"times_seen\": 4.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.012203566861423605, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08669416944347051, \"functional effect\": -0.4589, \"times_seen\": 10.0}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 548, \"wildtype\": \"V\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0034552447734203383, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08764026100514903, \"functional effect\": -2.2832, \"times_seen\": 3.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.008859889679308, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.08689533010890625, \"functional effect\": -2.7077, \"times_seen\": 1.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.011596125113442353, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.08813619787356046, \"functional effect\": -0.2605, \"times_seen\": 3.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.023116918573888225, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.0860408404745466, \"functional effect\": -2.5107, \"times_seen\": 4.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.6045072267868351, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.057502764207718035, \"functional effect\": -2.3878, \"times_seen\": 4.0}, {\"site\": 549, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.02404990826695671, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.0859852159220893, \"functional effect\": -1.0027, \"times_seen\": 8.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0026350583475661894, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08727106952322398, \"functional effect\": -1.3807, \"times_seen\": 6.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0013654850741375262, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.0875134050175487, \"functional effect\": -2.9624, \"times_seen\": 1.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.12969888472280322, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.0799135226740334, \"functional effect\": -1.3628, \"times_seen\": 16.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.005124984893826119, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08774175243030889, \"functional effect\": -0.9838, \"times_seen\": 10.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005594475678873933, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08709223283792905, \"functional effect\": -0.9395, \"times_seen\": 1.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0007650837849696729, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08738426079717274, \"functional effect\": -1.3033, \"times_seen\": 1.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.009467208464582948, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.0880062353797387, \"functional effect\": -0.3906, \"times_seen\": 3.0}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 550, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.005454193938845527, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08710070174066023, \"functional effect\": -1.8571, \"times_seen\": 2.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.02862541729238269, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08571294568917807, \"functional effect\": 0.3314, \"times_seen\": 9.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.1409463467126124, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.09640345705453053, \"functional effect\": -0.0665, \"times_seen\": 22.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.08958500034254949, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08216668346797715, \"functional effect\": -0.3478, \"times_seen\": 28.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.020372789707133587, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08620465322621315, \"functional effect\": -0.0396, \"times_seen\": 25.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.017851159317952343, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08635545873228488, \"functional effect\": -0.8793, \"times_seen\": 3.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03755353866328718, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.0897363233016695, \"functional effect\": -0.2673, \"times_seen\": 8.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04172599624578797, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08493814137701454, \"functional effect\": -0.203, \"times_seen\": 8.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.009136708368539189, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08798607676195638, \"functional effect\": -0.2402, \"times_seen\": 1.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05354964516054661, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08424487311428416, \"functional effect\": -0.5543, \"times_seen\": 21.0}, {\"site\": 551, \"wildtype\": \"E\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.007159378580713564, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08699781441071903, \"functional effect\": -2.6839, \"times_seen\": 2.0}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0068425611582270136, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.08701692132460806, \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0006432760562820774, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.08739163902152723, \"functional effect\": -2.2021, \"times_seen\": 1.0}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 552, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.011880081001782198, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.08671361047672117, \"functional effect\": -2.7942, \"times_seen\": 1.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.112967558463878, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.040422848195464975, \"functional effect\": -0.5338, \"times_seen\": 13.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.011985757713837749, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08816000427245893, \"functional effect\": -0.7417, \"times_seen\": 10.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.08118659468378595, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.09249177844618144, \"functional effect\": 0.306, \"times_seen\": 34.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03757696422169532, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08518276570334705, \"functional effect\": -0.7034, \"times_seen\": 8.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.3371105012322081, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.11044445149597323, \"functional effect\": -0.1276, \"times_seen\": 28.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.015236501771018145, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08651210630749122, \"functional effect\": -0.0048, \"times_seen\": 8.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.014877634889309826, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08653362866017855, \"functional effect\": -0.371, \"times_seen\": 3.0}, {\"site\": 553, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0010129169779193217, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08736925079179313, \"functional effect\": -0.3633, \"times_seen\": 9.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0054556328556821165, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.08710061486810562, \"functional effect\": -1.5022, \"times_seen\": 1.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03766561347449343, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.08974329467944525, \"functional effect\": -2.5659, \"times_seen\": 1.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.016774443772253705, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.08845311681190775, \"functional effect\": -0.1764, \"times_seen\": 2.0}, {\"site\": 554, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.24788944632466267, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.07362772321224921, \"functional effect\": -2.1692, \"times_seen\": 2.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015359733341662622, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08650471696523157, \"functional effect\": -1.6942, \"times_seen\": 7.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0066994474292387555, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08702555373370409, \"functional effect\": -0.1471, \"times_seen\": 5.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.036116172016958846, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08526906068286028, \"functional effect\": -0.3473, \"times_seen\": 37.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004907471561308949, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08713371559703866, \"functional effect\": -0.0113, \"times_seen\": 1.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0002103882686448183, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08741786524981855, \"functional effect\": -0.0286, \"times_seen\": 1.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.026370085935416485, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08904339635764265, \"functional effect\": -0.0761, \"times_seen\": 29.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.00883865486255312, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08796790116062031, \"functional effect\": -0.2543, \"times_seen\": 3.0}, {\"site\": 555, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.023601054278426056, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08887265513594678, \"functional effect\": -2.0137, \"times_seen\": 2.0}, {\"site\": 556, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 556, \"wildtype\": \"F\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.002766223849058889, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": 0.08759841463132999, \"functional effect\": -2.94, \"times_seen\": 1.0}, {\"site\": 556, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.026170790515361975, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": 0.08903109665818285, \"functional effect\": -2.0562, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.021069692824823325, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08616302157010632, \"functional effect\": -2.3067, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.005925525058265109, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.0870722504292389, \"functional effect\": -2.8505, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.030616828840437846, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08559471418899382, \"functional effect\": 0.0426, \"times_seen\": 22.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03390841601827011, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08539964780652283, \"functional effect\": -2.8971, \"times_seen\": 8.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.006938909821963372, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08785214100500538, \"functional effect\": -0.1031, \"times_seen\": 9.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00035492241250105694, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08740910786653759, \"functional effect\": 0.0248, \"times_seen\": 1.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.022253362157574227, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08609235750306721, \"functional effect\": -1.37, \"times_seen\": 4.0}, {\"site\": 557, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.03906222670225301, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08509511470381767, \"functional effect\": -1.0651, \"times_seen\": 6.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.008809723768042852, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08796613711342237, \"functional effect\": -0.3296, \"times_seen\": 4.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.012705759272773707, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08820401300651101, \"functional effect\": -0.5628, \"times_seen\": 1.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 2.894806347984327, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.6502600488750366, \"functional effect\": -0.3695, \"times_seen\": 8.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0029164866804789018, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08725404710647038, \"functional effect\": -2.3594, \"times_seen\": 5.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.018691034810497657, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08857070306791566, \"functional effect\": -0.5895, \"times_seen\": 3.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.028539729025022487, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08917740786127336, \"functional effect\": -0.3134, \"times_seen\": 21.0}, {\"site\": 558, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0028384783736156677, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08725876516836924, \"functional effect\": -0.603, \"times_seen\": 3.0}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.003048409033636464, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.08724606882095233, \"functional effect\": -2.9764, \"times_seen\": 2.0}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.013365402903372016, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.08662438070721194, \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 559, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005391698768123016, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.08710447488118662, \"functional effect\": -2.777, \"times_seen\": 1.0}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.00491328381515608, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.08713336455801851, \"functional effect\": -2.3202, \"times_seen\": 1.0}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.003557709137975673, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.08721527465552073, \"functional effect\": -2.927, \"times_seen\": 1.0}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 560, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005558159621061243, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.08709442518369974, \"functional effect\": -2.9788, \"times_seen\": 1.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006917757063356289, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08701238596165659, \"functional effect\": -1.592, \"times_seen\": 3.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.12492823146983592, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.09533901813080349, \"functional effect\": -2.4726, \"times_seen\": 5.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.02827276455814139, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08573389994384552, \"functional effect\": 0.2282, \"times_seen\": 5.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.032430448173533064, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08941822973498854, \"functional effect\": -1.6206, \"times_seen\": 4.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.060477550937777354, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.0911735965472693, \"functional effect\": -0.7601, \"times_seen\": 8.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.009417639685634234, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08686174262005379, \"functional effect\": -2.4087, \"times_seen\": 1.0}, {\"site\": 561, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005816081922825929, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08707885599818392, \"functional effect\": 0.2389, \"times_seen\": 2.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.00892369416403924, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08689148716981883, \"functional effect\": -0.4081, \"times_seen\": 10.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.055586106280748886, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.084126039697982, \"functional effect\": -0.9586, \"times_seen\": 3.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.007336521232886668, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08787635667549692, \"functional effect\": 0.2013, \"times_seen\": 7.0}, {\"site\": 562, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.009830995654444955, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.0880284296598737, \"functional effect\": -0.0016, \"times_seen\": 6.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.015495838322353262, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.08649655642738756, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.04157876889957029, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.08494680977532114, \"functional effect\": -1.6099, \"times_seen\": 7.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.7752697997682082, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.05108390228581702, \"functional effect\": -2.1732, \"times_seen\": 2.0}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 563, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.12881600452561734, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.07996244199336465, \"functional effect\": -0.7948, \"times_seen\": 21.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.002462223882336227, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08728152519939679, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0258741306248969, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08587656023122019, \"functional effect\": -2.5503, \"times_seen\": 9.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.004202691649583524, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08768567837301028, \"functional effect\": -0.1, \"times_seen\": 11.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.8693208860804541, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.15971848884742748, \"functional effect\": 0.0704, \"times_seen\": 30.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.007500351500352522, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08788633634831812, \"functional effect\": -0.4411, \"times_seen\": 11.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.002639324162931781, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08727081147720012, \"functional effect\": -0.3508, \"times_seen\": 4.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1768198233166164, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.07734557266552787, \"functional effect\": -1.2128, \"times_seen\": 8.0}, {\"site\": 564, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.00012299003325379293, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08743806812438097, \"functional effect\": -0.1585, \"times_seen\": 3.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.005056543397038507, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.0871247126466471, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.009449871934357526, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.08685980200340371, \"functional effect\": -1.9319, \"times_seen\": 3.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.012311444489065548, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.0866876871229441, \"functional effect\": -1.7188, \"times_seen\": 8.0}, {\"site\": 565, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.024550505770583406, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.08595538528136779, \"functional effect\": -2.0757, \"times_seen\": 9.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004840799568608962, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08713774244437887, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.024442166005311933, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.0859618403780228, \"functional effect\": -1.2127, \"times_seen\": 11.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.026329050940238456, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08584948532490412, \"functional effect\": 0.0508, \"times_seen\": 7.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.012882886006746521, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08665335752953379, \"functional effect\": -0.8953, \"times_seen\": 9.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.008293732299063092, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08793468094355833, \"functional effect\": -0.4726, \"times_seen\": 6.0}, {\"site\": 566, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.008017951248350386, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08791787323276738, \"functional effect\": -0.0367, \"times_seen\": 23.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0005980561573400715, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08739437827196264, \"functional effect\": -2.7409, \"times_seen\": 2.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0042088709730086745, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08717591883727012, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0988188680897908, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.09362912686244085, \"functional effect\": -2.8571, \"times_seen\": 7.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.05313625361645356, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08426901619873833, \"functional effect\": -2.3645, \"times_seen\": 13.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005437297659523685, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08710172183594157, \"functional effect\": -2.8609, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0111820509634107, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08811090515167146, \"functional effect\": -2.2365, \"times_seen\": 14.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.17930288549224338, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.07721256556376435, \"functional effect\": -1.323, \"times_seen\": 63.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.007814490552731954, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08695831862672769, \"functional effect\": -2.6726, \"times_seen\": 2.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.11080717584631561, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.09441039477437072, \"functional effect\": -2.3606, \"times_seen\": 8.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.03437492684213364, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08953882976557508, \"functional effect\": -2.0229, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.05218955189119696, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.09065132379411044, \"functional effect\": -2.2957, \"times_seen\": 14.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.011497615968334908, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08813018002165873, \"functional effect\": -2.9093, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.002661072875409395, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08726949587450769, \"functional effect\": -2.6227, \"times_seen\": 2.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.012555404897604169, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08667302943371101, \"functional effect\": -2.4414, \"times_seen\": 7.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02052278157909696, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08619569130091134, \"functional effect\": -2.5472, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.00011083227592118759, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08743733127681129, \"functional effect\": -2.621, \"times_seen\": 11.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.0265225154505564, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.17810560966328948, \"functional effect\": -0.1169, \"times_seen\": 140.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.432551945788603, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.11799799837169161, \"functional effect\": 0.0316, \"times_seen\": 138.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.648854293608093, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.05576207481467136, \"functional effect\": -1.4471, \"times_seen\": 88.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.008724350814300216, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08690349416807927, \"functional effect\": -2.4598, \"times_seen\": 4.0}, {\"site\": 567, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03838708253781752, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08513494634771178, \"functional effect\": -1.6172, \"times_seen\": 34.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0490007324752221, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.09045117652880942, \"functional effect\": -0.0272, \"times_seen\": 14.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.04565469439172306, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.0847071553640262, \"functional effect\": 0.0333, \"times_seen\": 23.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.020743760774094542, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.08618248962262814, \"functional effect\": -3.0583, \"times_seen\": 2.0}, {\"site\": 568, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.8118441743291392, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.04980513042021858, \"functional effect\": -2.0572, \"times_seen\": 20.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.023230640871070827, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08603405846163682, \"functional effect\": -2.7558, \"times_seen\": 1.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.036469510400624995, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.0852481795250156, \"functional effect\": 0.1502, \"times_seen\": 45.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.023744186754663294, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08600343898031958, \"functional effect\": -1.1717, \"times_seen\": 13.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.025290291151889153, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08897677616445197, \"functional effect\": -1.2113, \"times_seen\": 7.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.007530712759154455, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08788818591999126, \"functional effect\": -1.2738, \"times_seen\": 12.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.04376138431041945, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.09012328622164473, \"functional effect\": -0.1425, \"times_seen\": 5.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.23707233616172094, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.1030455909726755, \"functional effect\": -0.3767, \"times_seen\": 51.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -1.295475118799587, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.03561940499986693, \"functional effect\": 0.3283, \"times_seen\": 17.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05823781745478125, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.09103216254842975, \"functional effect\": -1.2776, \"times_seen\": 28.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.4008287812327933, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.03311098099705112, \"functional effect\": 0.401, \"times_seen\": 12.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.09725300451544729, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.0935275593791527, \"functional effect\": -1.1166, \"times_seen\": 24.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03706279867264942, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08521312960412147, \"functional effect\": -0.0921, \"times_seen\": 16.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0004330230323456444, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08745686045314324, \"functional effect\": -1.2249, \"times_seen\": 48.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.012416507680460041, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08668137438658369, \"functional effect\": -2.7875, \"times_seen\": 2.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016944792803627946, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08640972819696219, \"functional effect\": 0.3372, \"times_seen\": 13.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.21265691066594078, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.07544794600978279, \"functional effect\": -0.6641, \"times_seen\": 53.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.08957986547844753, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08216697591751929, \"functional effect\": 0.1456, \"times_seen\": 57.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.11916868298144721, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08049894373880123, \"functional effect\": -0.7735, \"times_seen\": 19.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.04270220022312792, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.0900571446493655, \"functional effect\": -0.502, \"times_seen\": 13.0}, {\"site\": 569, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02861853731454375, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08571335444124017, \"functional effect\": -0.0262, \"times_seen\": 19.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01043191558335076, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08680069658669998, \"functional effect\": -1.4135, \"times_seen\": 8.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03655340057551521, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08524322263768483, \"functional effect\": 0.2755, \"times_seen\": 31.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.017440130449587907, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08638006520989788, \"functional effect\": -1.3074, \"times_seen\": 3.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014769864057050342, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08654009305441784, \"functional effect\": 0.2203, \"times_seen\": 4.0}, {\"site\": 570, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0032549727713754154, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08723357790398657, \"functional effect\": -2.1183, \"times_seen\": 1.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.006469657444295992, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.08703941611819392, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03587873066499325, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08528309557357627, \"functional effect\": -1.7645, \"times_seen\": 6.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.09475298078834925, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08187287490156557, \"functional effect\": 0.397, \"times_seen\": 41.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01763433586130625, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08850585339509076, \"functional effect\": -0.6174, \"times_seen\": 5.0}, {\"site\": 571, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.026210342561170757, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08903353751379255, \"functional effect\": -2.0659, \"times_seen\": 16.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0032677631759581967, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.08762887268807819, \"functional effect\": -2.1062, \"times_seen\": 7.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.375578093771173, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.03369560530124571, \"functional effect\": 0.1167, \"times_seen\": 57.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.037029517591024644, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.08521509538188667, \"functional effect\": -1.6023, \"times_seen\": 29.0}, {\"site\": 572, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.009381843163185988, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.08686389788281325, \"functional effect\": -2.2746, \"times_seen\": 11.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.002650153235563834, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08727015641262827, \"functional effect\": -2.0367, \"times_seen\": 1.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0008136821029404922, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08747993923185504, \"functional effect\": -2.8705, \"times_seen\": 1.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0183880382798127, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08632332872405464, \"functional effect\": 0.2586, \"times_seen\": 25.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.028716740423947118, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08918835015032664, \"functional effect\": -0.7482, \"times_seen\": 4.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.010310583435302228, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08805769736778486, \"functional effect\": -1.4259, \"times_seen\": 4.0}, {\"site\": 573, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.004337208165329207, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08769385454434776, \"functional effect\": -2.4292, \"times_seen\": 5.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.018328248298140674, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08632690631810425, \"functional effect\": -0.2346, \"times_seen\": 17.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05598609252136512, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08410271904239161, \"functional effect\": -1.9766, \"times_seen\": 2.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.022162868838839386, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08609775783180726, \"functional effect\": -2.1163, \"times_seen\": 10.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.007093308520476883, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08700179867786839, \"functional effect\": -2.9583, \"times_seen\": 2.0}, {\"site\": 574, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.005630653015836269, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08709004892139743, \"functional effect\": -1.2552, \"times_seen\": 1.0}, {\"site\": 575, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 575, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.006402535828797442, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": 0.08704346573503163, \"functional effect\": -2.333, \"times_seen\": 2.0}, {\"site\": 576, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.003414353643980004, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": 0.08722394135889693, \"functional effect\": -0.8443, \"times_seen\": 1.0}, {\"site\": 576, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 576, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.025521330326656613, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": 0.0889910264158877, \"functional effect\": -2.2045, \"times_seen\": 1.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.009899433840267528, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.0868327396141922, \"functional effect\": -0.9949, \"times_seen\": 5.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.085571051176687, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08239561066271806, \"functional effect\": -1.1274, \"times_seen\": 22.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.00477869779508669, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08714149342754833, \"functional effect\": -0.185, \"times_seen\": 9.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.10379029969095138, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08136161048509961, \"functional effect\": 0.0657, \"times_seen\": 53.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03789570755698019, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08516394783890949, \"functional effect\": 0.2053, \"times_seen\": 5.0}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 577, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.12989802290988287, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.07990249280609996, \"functional effect\": -0.0238, \"times_seen\": 44.0}, {\"site\": 578, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.015280244401346491, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": 0.08836155333598322, \"functional effect\": -2.5045, \"times_seen\": 5.0}, {\"site\": 578, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05938367499698886, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": 0.08390488810036953, \"functional effect\": -0.5312, \"times_seen\": 20.0}, {\"site\": 578, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -1.1155228585873593, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.04035131465286204, \"functional effect\": 0.0603, \"times_seen\": 48.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.020597002047539708, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08619125701657124, \"functional effect\": 0.3607, \"times_seen\": 3.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.010622251448897169, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08678924565946892, \"functional effect\": -0.0263, \"times_seen\": 2.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03412559794439097, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08952335685680311, \"functional effect\": 0.3336, \"times_seen\": 6.0}, {\"site\": 579, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.041254222573142665, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08996680309293012, \"functional effect\": -3.2007, \"times_seen\": 1.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.014910983310259352, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08653162842697568, \"functional effect\": -1.1563, \"times_seen\": 3.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.025556792752496175, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.0858954518760569, \"functional effect\": -1.0418, \"times_seen\": 15.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.007763199782195458, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08696141022843516, \"functional effect\": -2.4049, \"times_seen\": 2.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.03539914087544652, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.0896024187319713, \"functional effect\": -1.3008, \"times_seen\": 17.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005074363987084086, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08712363646342489, \"functional effect\": -3.0176, \"times_seen\": 1.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06239290234832551, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08373005853858594, \"functional effect\": -0.8469, \"times_seen\": 12.0}, {\"site\": 580, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.012572429052323131, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08819586179176672, \"functional effect\": -2.1047, \"times_seen\": 4.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.021285829867686755, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08873014745273297, \"functional effect\": -2.627, \"times_seen\": 1.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013498819644648495, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08661637027680877, \"functional effect\": -2.6452, \"times_seen\": 3.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0032423378787221294, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08723434188506902, \"functional effect\": -2.0253, \"times_seen\": 1.0}, {\"site\": 581, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.02385085276494352, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.0859970805301087, \"functional effect\": 0.3752, \"times_seen\": 9.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.002393325074077663, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08728569360401225, \"functional effect\": -1.1432, \"times_seen\": 16.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.17215657805377152, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.07759598242755428, \"functional effect\": -0.1092, \"times_seen\": 11.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.024495167187150082, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08595868240262595, \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.010496094813511865, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08806902114353772, \"functional effect\": -0.8359, \"times_seen\": 14.0}, {\"site\": 582, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0038415847813382917, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08719811520335162, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.03841601718960216, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.0897899859183733, \"functional effect\": -1.4963, \"times_seen\": 6.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.007649924745113651, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08696823838228178, \"functional effect\": -1.31, \"times_seen\": 2.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04649074577964918, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08465808122391347, \"functional effect\": -0.2218, \"times_seen\": 14.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.022529371702841423, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08607588829864721, \"functional effect\": -0.7711, \"times_seen\": 6.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004900565078735501, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08713413272533793, \"functional effect\": -0.6072, \"times_seen\": 3.0}, {\"site\": 583, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.019269777614358934, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08627058617118791, \"functional effect\": -2.9842, \"times_seen\": 2.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.003760889367581408, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08720299266156568, \"functional effect\": -2.9847, \"times_seen\": 1.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.012893635670523759, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08665271186918154, \"functional effect\": -1.7824, \"times_seen\": 2.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.007327945346715401, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08698765004257135, \"functional effect\": -2.7277, \"times_seen\": 1.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004451675597010407, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08716124842216287, \"functional effect\": -2.2331, \"times_seen\": 2.0}, {\"site\": 584, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011780512810282476, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08671959525872458, \"functional effect\": -1.6721, \"times_seen\": 3.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.10184125092519766, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.09382548138197089, \"functional effect\": -0.7151, \"times_seen\": 14.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.9413977449660825, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.04552758049289009, \"functional effect\": -1.1483, \"times_seen\": 22.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.04413439499372975, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08479646607158237, \"functional effect\": -0.6462, \"times_seen\": 10.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.014012338867947425, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08658554515104604, \"functional effect\": 0.0031, \"times_seen\": 3.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.013580549901178855, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08661146350341314, \"functional effect\": -0.4023, \"times_seen\": 5.0}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 585, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.013676722055198346, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08660569004946342, \"functional effect\": -0.4268, \"times_seen\": 5.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004365444815402708, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08716645825999157, \"functional effect\": -2.8352, \"times_seen\": 1.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.008519923971065123, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08691580908231626, \"functional effect\": -2.9777, \"times_seen\": 2.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0013542299013991877, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08734858341136702, \"functional effect\": -2.5671, \"times_seen\": 2.0}, {\"site\": 586, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.038679805316762794, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08980640497927148, \"functional effect\": -2.3969, \"times_seen\": 5.0}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.006552289427280162, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.08703443098039285, \"functional effect\": -2.9043, \"times_seen\": 1.0}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.012543826747254943, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.08667372501896248, \"functional effect\": -2.9197, \"times_seen\": 3.0}, {\"site\": 587, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0049019598558721214, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.08713404848533297, \"functional effect\": -2.9917, \"times_seen\": 1.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.03836384974630668, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08978673919666216, \"functional effect\": -0.3383, \"times_seen\": 4.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0016932742261495622, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08732805824074276, \"functional effect\": -0.936, \"times_seen\": 1.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.03382226395653904, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08540474768917414, \"functional effect\": -1.3641, \"times_seen\": 28.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03886655232662391, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.0898180305568318, \"functional effect\": 0.07, \"times_seen\": 6.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0060620283722844, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08706401231367604, \"functional effect\": -1.8018, \"times_seen\": 2.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.02214040793295906, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08878272218126453, \"functional effect\": -1.303, \"times_seen\": 6.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03798991680477649, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.0897634703367422, \"functional effect\": -0.2819, \"times_seen\": 10.0}, {\"site\": 588, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.002977815892827662, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08725033800087803, \"functional effect\": -1.843, \"times_seen\": 3.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.0350957030194625, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.04266469791387221, \"functional effect\": -2.971, \"times_seen\": 2.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02540244850945956, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.08590464174454146, \"functional effect\": -2.4882, \"times_seen\": 4.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.008013277412117914, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.08694633759144035, \"functional effect\": -2.8179, \"times_seen\": 1.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.004993182273373957, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.0877337368315031, \"functional effect\": -0.25, \"times_seen\": 20.0}, {\"site\": 589, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04815082166521973, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.09039790623203299, \"functional effect\": -0.2666, \"times_seen\": 2.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005956317616336785, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.0870703919985666, \"functional effect\": -1.2492, \"times_seen\": 1.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005817991918474988, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08707874071385753, \"functional effect\": -2.9055, \"times_seen\": 1.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03344193378761157, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.0854272654653512, \"functional effect\": -2.2234, \"times_seen\": 8.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.016573132611269588, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08643199152518595, \"functional effect\": -1.7069, \"times_seen\": 5.0}, {\"site\": 590, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.09158023685640648, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08205312609832041, \"functional effect\": -1.6035, \"times_seen\": 7.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.0016798313479519334, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.0875324752362807, \"functional effect\": -2.0412, \"times_seen\": 2.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.005553869910572123, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08776784021459207, \"functional effect\": -1.2151, \"times_seen\": 5.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0019131261689385286, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.0873147513533477, \"functional effect\": -0.7032, \"times_seen\": 10.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.012181750250301288, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08817198177018766, \"functional effect\": -0.9029, \"times_seen\": 6.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.007071600440209742, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08786022150065317, \"functional effect\": -0.7007, \"times_seen\": 17.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0038029479499526583, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08720045048828196, \"functional effect\": 0.0355, \"times_seen\": 13.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003612632890945499, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08721195441189064, \"functional effect\": -2.1905, \"times_seen\": 6.0}, {\"site\": 591, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.008238837649166665, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08693274490349387, \"functional effect\": -1.4738, \"times_seen\": 1.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.029607735488169133, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08565460437264255, \"functional effect\": -0.8661, \"times_seen\": 1.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.028140222840932216, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08915271657688956, \"functional effect\": -2.6389, \"times_seen\": 1.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0024799912834185247, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08728045029702851, \"functional effect\": -0.5895, \"times_seen\": 1.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04620460954427663, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.09027604063949662, \"functional effect\": -0.1331, \"times_seen\": 6.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004815673728147368, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08713926004027972, \"functional effect\": -0.7692, \"times_seen\": 5.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.006433160309320039, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08704161805929052, \"functional effect\": -3.0332, \"times_seen\": 2.0}, {\"site\": 592, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0069809796072285895, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08700857294248225, \"functional effect\": -0.0969, \"times_seen\": 2.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01244424912122595, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08667970761500307, \"functional effect\": -1.042, \"times_seen\": 7.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.01179206695912815, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08671890074805474, \"functional effect\": -0.651, \"times_seen\": 3.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.014368089346859087, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08656419687521805, \"functional effect\": -2.2683, \"times_seen\": 3.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01918576215323675, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08627561029196387, \"functional effect\": -0.941, \"times_seen\": 4.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0060095269643004575, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08706718073546613, \"functional effect\": -1.3007, \"times_seen\": 4.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.008624667814838168, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08690949897159064, \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 593, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03548752657159904, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08530622424522971, \"functional effect\": -1.4555, \"times_seen\": 2.0}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0041814729643293354, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.08717757439800382, \"functional effect\": -1.6931, \"times_seen\": 2.0}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.043857092675158034, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.0901292651972567, \"functional effect\": -0.7923, \"times_seen\": 7.0}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.00423383313839347, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.08717441049294503, \"functional effect\": -1.8609, \"times_seen\": 1.0}, {\"site\": 594, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.006285208862681688, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.08705054482017686, \"functional effect\": -1.5147, \"times_seen\": 1.0}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004197084422685965, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.0871766310512325, \"functional effect\": -2.1948, \"times_seen\": 1.0}, {\"site\": 595, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.005438845045179016, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.08710162841364592, \"functional effect\": -0.7859, \"times_seen\": 17.0}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.009087835291055122, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.08688160174364763, \"functional effect\": -2.4833, \"times_seen\": 2.0}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0703036333486312, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.08327219787524572, \"functional effect\": -1.9985, \"times_seen\": 11.0}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004933849975860125, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.08713212244797124, \"functional effect\": -2.6961, \"times_seen\": 1.0}, {\"site\": 596, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.026334227275219564, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.08904118318221654, \"functional effect\": 0.3906, \"times_seen\": 2.0}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01589720645217063, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.0864724958107646, \"functional effect\": -2.586, \"times_seen\": 5.0}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.009431167417462617, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.08686092814657324, \"functional effect\": -2.9757, \"times_seen\": 2.0}, {\"site\": 597, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004565036487060685, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.08715439992803332, \"functional effect\": -2.8966, \"times_seen\": 1.0}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0020036459044403838, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.08755212420576886, \"functional effect\": -2.6823, \"times_seen\": 1.0}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.017368852310308894, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.08638433302966875, \"functional effect\": -3.0564, \"times_seen\": 4.0}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 598, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004312071573484261, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.08716968308740917, \"functional effect\": -2.9556, \"times_seen\": 1.0}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011777440496483962, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.08671977993399223, \"functional effect\": -1.4786, \"times_seen\": 1.0}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005414988327970876, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.08710306875691974, \"functional effect\": -2.3935, \"times_seen\": 1.0}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005302616125979697, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.08710985352054854, \"functional effect\": -0.1275, \"times_seen\": 1.0}, {\"site\": 599, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.012886432489178532, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08665314451554004, \"functional effect\": 0.1276, \"times_seen\": 8.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.002273938783129288, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08756852887340777, \"functional effect\": -0.5201, \"times_seen\": 9.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.019329062528617384, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08626704111206297, \"functional effect\": -0.5396, \"times_seen\": 6.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02589694706876619, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08587520209095723, \"functional effect\": 0.0118, \"times_seen\": 13.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005142069705027795, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08711954784470996, \"functional effect\": 0.0945, \"times_seen\": 1.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.07076935379916685, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.09182633019128131, \"functional effect\": -0.2211, \"times_seen\": 19.0}, {\"site\": 600, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.022669079874230825, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08606755325737513, \"functional effect\": -0.2757, \"times_seen\": 20.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.04695727835485035, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08463070928027329, \"functional effect\": -0.1977, \"times_seen\": 32.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03124594857224838, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08555739681927316, \"functional effect\": 0.0939, \"times_seen\": 76.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04030675845722089, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08502173959400607, \"functional effect\": -0.4228, \"times_seen\": 44.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.006464519961441683, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08703972606887059, \"functional effect\": -0.5434, \"times_seen\": 2.0}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 601, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.006472915229905736, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08703921957254213, \"functional effect\": 0.0637, \"times_seen\": 6.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.002174154687665424, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08756247239991631, \"functional effect\": -1.6258, \"times_seen\": 8.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004592882644806052, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08715271773486122, \"functional effect\": -1.3301, \"times_seen\": 2.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.007016171331514665, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08700645056437911, \"functional effect\": -2.9726, \"times_seen\": 1.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.007379394896443248, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08698454793471194, \"functional effect\": -1.7384, \"times_seen\": 6.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.006278395919088189, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08705095590625894, \"functional effect\": 0.1573, \"times_seen\": 1.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.009247771499876392, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08687197064115532, \"functional effect\": -2.5998, \"times_seen\": 3.0}, {\"site\": 602, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.01510034644878997, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.0865202713314388, \"functional effect\": 0.0398, \"times_seen\": 19.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.060791905118141525, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.0911934648653352, \"functional effect\": -0.9545, \"times_seen\": 7.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004019744839696902, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.0871873476733737, \"functional effect\": -0.7121, \"times_seen\": 1.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07442763070479808, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.083034501099272, \"functional effect\": -0.0215, \"times_seen\": 10.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.003502533565847089, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.08764313373286833, \"functional effect\": -0.4306, \"times_seen\": 17.0}, {\"site\": 603, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004837373580409589, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.0871379493718468, \"functional effect\": -1.1502, \"times_seen\": 6.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006537008629276165, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08703535284022107, \"functional effect\": -2.9643, \"times_seen\": 1.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06419054626743156, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08362579319430198, \"functional effect\": -0.374, \"times_seen\": 56.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.09831485230375912, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08167098818433138, \"functional effect\": -0.0725, \"times_seen\": 54.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02607811282935838, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08586441902933943, \"functional effect\": -0.1144, \"times_seen\": 16.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.005504684577861532, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08776484802517326, \"functional effect\": -0.2201, \"times_seen\": 38.0}, {\"site\": 604, \"wildtype\": \"Q\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.07952492040983498, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08274164358861728, \"functional effect\": 0.0911, \"times_seen\": 15.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.008278665843159548, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08693034500168641, \"functional effect\": -0.6953, \"times_seen\": 2.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009516951349470728, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08685576347197614, \"functional effect\": -0.2404, \"times_seen\": 7.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.028787612271697103, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08919273160188311, \"functional effect\": -0.1307, \"times_seen\": 20.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.026439611405768865, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08904768758552636, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 605, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.12586990552708066, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.08012589855296204, \"functional effect\": -2.4976, \"times_seen\": 7.0}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004079292156717686, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.08718374908507813, \"functional effect\": -2.2921, \"times_seen\": 2.0}, {\"site\": 606, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0009714495878154887, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.08737176208265576, \"functional effect\": -2.7193, \"times_seen\": 5.0}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00836545800874341, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.08692511545161549, \"functional effect\": -0.3049, \"times_seen\": 3.0}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01639826735638439, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.08644246835348163, \"functional effect\": -1.1414, \"times_seen\": 12.0}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.02456859628493428, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.08893227748507514, \"functional effect\": -2.8599, \"times_seen\": 1.0}, {\"site\": 607, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.8604845001778424, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.1587432163037277, \"functional effect\": -0.9023, \"times_seen\": 84.0}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.013146803345691798, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.08663750717223309, \"functional effect\": -1.4612, \"times_seen\": 4.0}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.006461083923492411, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.0878230488710841, \"functional effect\": -2.9813, \"times_seen\": 1.0}, {\"site\": 608, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0005020285450450513, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.08746104370023013, \"functional effect\": -1.9878, \"times_seen\": 2.0}, {\"site\": 609, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005324586152005385, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": 0.08710852698159012, \"functional effect\": -2.9522, \"times_seen\": 1.0}, {\"site\": 609, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 9.476290235436378e-05, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": 0.08743635736668123, \"functional effect\": -0.6197, \"times_seen\": 6.0}, {\"site\": 609, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.024312899441312187, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08596954296884214, \"functional effect\": -2.5233, \"times_seen\": 1.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0497372671906372, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.09049736608261846, \"functional effect\": -0.0633, \"times_seen\": 17.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.009025884685398163, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.0879793181842213, \"functional effect\": 0.0786, \"times_seen\": 18.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.042375528892630424, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08489990898784078, \"functional effect\": -1.4795, \"times_seen\": 11.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0280869992577399, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08574493998254551, \"functional effect\": -1.6206, \"times_seen\": 5.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.012509498581807747, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08819201476528206, \"functional effect\": -1.1987, \"times_seen\": 2.0}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 610, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.4049579058717947, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.03301634983906647, \"functional effect\": -0.1161, \"times_seen\": 60.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005641726269933896, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08708938047344912, \"functional effect\": -1.5617, \"times_seen\": 1.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.010169063904382838, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08681651267171159, \"functional effect\": -0.7202, \"times_seen\": 18.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.013474583763649468, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08661782536025722, \"functional effect\": -2.8353, \"times_seen\": 2.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.1137698019286308, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.040400376397814845, \"functional effect\": -0.1259, \"times_seen\": 15.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.008609235997159587, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.086910428605836, \"functional effect\": -1.4898, \"times_seen\": 3.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0804175413137075, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.09244248725404418, \"functional effect\": -3.0182, \"times_seen\": 2.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.011037237709678105, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.0867642846219527, \"functional effect\": -0.6028, \"times_seen\": 2.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.059156671898940694, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08391809128437089, \"functional effect\": -1.8835, \"times_seen\": 1.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.017599546389819257, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08637052085149435, \"functional effect\": -1.5818, \"times_seen\": 6.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.3060962792066506, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.21619103825637112, \"functional effect\": -1.0809, \"times_seen\": 10.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.010157782996595565, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08681719152127794, \"functional effect\": -1.0646, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -3.939540293651266, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.005698279302170095, \"functional effect\": 0.1571, \"times_seen\": 11.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0013543521394097282, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08734857601041512, \"functional effect\": -3.008, \"times_seen\": 1.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.004383350133260445, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08769665931709458, \"functional effect\": -0.9781, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 1.6675871841105394, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.27775206263063057, \"functional effect\": -1.5402, \"times_seen\": 21.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.3002839784179081, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.10766090214891293, \"functional effect\": -0.612, \"times_seen\": 38.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.1131427545527072, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08083587935445699, \"functional effect\": -1.6407, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.012954848248162175, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08664903533105217, \"functional effect\": -2.6495, \"times_seen\": 7.0}, {\"site\": 611, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.01868278365486154, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08630569450317761, \"functional effect\": -2.742, \"times_seen\": 5.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.041172109398889885, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08996168264173307, \"functional effect\": -0.5794, \"times_seen\": 13.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005752882593783248, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.08708267069613408, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0018894618105293618, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08731618357877176, \"functional effect\": -1.6823, \"times_seen\": 6.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02230002289847075, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08879254534879832, \"functional effect\": 0.0285, \"times_seen\": 15.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.019887262353671525, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08864417296197279, \"functional effect\": -0.5605, \"times_seen\": 8.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.010853228161013723, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08677535173912362, \"functional effect\": -0.132, \"times_seen\": 26.0}, {\"site\": 612, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.01988090629985898, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.08623404950658446, \"functional effect\": -0.0954, \"times_seen\": 12.0}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.10914143816987708, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.09430145130808729, \"functional effect\": 0.045, \"times_seen\": 50.0}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.012280238927914803, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.08668956220194639, \"functional effect\": 0.2989, \"times_seen\": 4.0}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 613, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.020440082797022904, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.0886781466706838, \"functional effect\": 0.0998, \"times_seen\": 9.0}, {\"site\": 614, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 614, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0028149621528931034, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": 0.08726018751546796, \"functional effect\": -2.5849, \"times_seen\": 1.0}, {\"site\": 614, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02686840337553257, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": 0.08907415791163886, \"functional effect\": -2.6836, \"times_seen\": 2.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.024183458377655523, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.0859772566491381, \"functional effect\": 0.2089, \"times_seen\": 30.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.6941310672825507, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.054039243141756066, \"functional effect\": -0.0548, \"times_seen\": 30.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.044975404118175355, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.09019915638061095, \"functional effect\": 0.2881, \"times_seen\": 13.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.06624165927984361, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.09153859796953086, \"functional effect\": 0.3502, \"times_seen\": 6.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0015521491614888317, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.08752472873202627, \"functional effect\": -0.3306, \"times_seen\": 10.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.016770319644776623, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.08845286395777176, \"functional effect\": -0.0955, \"times_seen\": 8.0}, {\"site\": 615, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.051810382247212204, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.090627501910254, \"functional effect\": -0.506, \"times_seen\": 6.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.026182215216263665, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.08903180169815933, \"functional effect\": -0.3661, \"times_seen\": 28.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.005139840912878306, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.0877426559475597, \"functional effect\": -1.2736, \"times_seen\": 19.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.5281767760343521, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.12608417542731634, \"functional effect\": -0.7037, \"times_seen\": 39.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09712058087196201, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.0935189749649627, \"functional effect\": -0.3618, \"times_seen\": 15.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.01682839994914979, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.0884564249824705, \"functional effect\": -0.6991, \"times_seen\": 4.0}, {\"site\": 616, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05288876915387053, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.08428347321181949, \"functional effect\": -1.0595, \"times_seen\": 10.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009418928920493038, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.08686166499787219, \"functional effect\": -2.9745, \"times_seen\": 2.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.007873822709130764, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.08695474245967705, \"functional effect\": -1.8411, \"times_seen\": 2.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0028472053393879195, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.08760333185157841, \"functional effect\": -1.49, \"times_seen\": 7.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.024940467565151923, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.0859321546015606, \"functional effect\": -1.9799, \"times_seen\": 4.0}, {\"site\": 617, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0119889062078486, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08670706975234137, \"functional effect\": 0.2404, \"times_seen\": 2.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.013669633172811847, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08660611559959126, \"functional effect\": -0.185, \"times_seen\": 1.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.08959124773719551, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.0821663276571007, \"functional effect\": -0.2754, \"times_seen\": 13.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.6353292586471742, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.02814364670459818, \"functional effect\": -1.4398, \"times_seen\": 9.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02138315696858981, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08614430237927832, \"functional effect\": -0.8676, \"times_seen\": 2.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03771949213694566, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08974664628101987, \"functional effect\": 0.0839, \"times_seen\": 21.0}, {\"site\": 618, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04084518481905764, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.0849900146602343, \"functional effect\": -0.8725, \"times_seen\": 11.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.004026982612420819, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.0871869102693444, \"functional effect\": -2.9006, \"times_seen\": 1.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.14306077469953396, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.09654485049421091, \"functional effect\": -0.2054, \"times_seen\": 74.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.07819308211549826, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08281806262896566, \"functional effect\": -0.7004, \"times_seen\": 16.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.058181397438457974, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08397483982683202, \"functional effect\": 0.1215, \"times_seen\": 25.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0690355804271926, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08334542192466722, \"functional effect\": -0.0828, \"times_seen\": 46.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.7068028452072033, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.14270276478010083, \"functional effect\": -0.0222, \"times_seen\": 48.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.5460793925146477, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.05987937418937196, \"functional effect\": 0.3922, \"times_seen\": 90.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0005567966839264334, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08746436399272083, \"functional effect\": 0.0315, \"times_seen\": 9.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.048450793323971786, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08454314272925788, \"functional effect\": -0.0573, \"times_seen\": 17.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.008679780963413344, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.0879582144052354, \"functional effect\": -0.264, \"times_seen\": 19.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.28736464597679284, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.1067011028083133, \"functional effect\": 0.0054, \"times_seen\": 110.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0788483002934974, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08278045829949135, \"functional effect\": 0.0884, \"times_seen\": 33.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.035067395552325555, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.0895818171736752, \"functional effect\": -0.078, \"times_seen\": 19.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0018699693022884102, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08731736333116424, \"functional effect\": -0.457, \"times_seen\": 24.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0037005954253926227, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08720663717542308, \"functional effect\": 0.0915, \"times_seen\": 20.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.7590845395263905, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.02583011374663021, \"functional effect\": -0.3886, \"times_seen\": 66.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.12586295310588624, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08012628468469592, \"functional effect\": 0.1195, \"times_seen\": 47.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010576127136296009, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08679202043735045, \"functional effect\": 0.0777, \"times_seen\": 22.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.07073608189130379, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.09182421248665158, \"functional effect\": -0.0497, \"times_seen\": 19.0}, {\"site\": 619, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.29373927561182106, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.07132457575241011, \"functional effect\": -0.0704, \"times_seen\": 15.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010489438500934022, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.0867972357515026, \"functional effect\": 0.2509, \"times_seen\": 2.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.10407777424951387, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08134539980838738, \"functional effect\": -0.1413, \"times_seen\": 17.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.007735119328365042, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08790063913760034, \"functional effect\": -0.205, \"times_seen\": 43.0}, {\"site\": 620, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.02882903296263898, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08919529241861872, \"functional effect\": -0.3156, \"times_seen\": 48.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.006402278329098729, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08781946919472093, \"functional effect\": 0.197, \"times_seen\": 1.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.009110571302849693, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08688023255230713, \"functional effect\": 0.3237, \"times_seen\": 3.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0008062286757595994, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08738176868033849, \"functional effect\": -1.5897, \"times_seen\": 6.0}, {\"site\": 621, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.024576148507035316, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08595385750755509, \"functional effect\": -0.3589, \"times_seen\": 14.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.09910583477470775, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08162622292741713, \"functional effect\": -0.6508, \"times_seen\": 5.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0030176520172832833, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08724792885186242, \"functional effect\": 0.0723, \"times_seen\": 10.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.025805818127313886, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08900857645728244, \"functional effect\": -0.2539, \"times_seen\": 6.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04449398538353683, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08477533326548682, \"functional effect\": 0.3651, \"times_seen\": 27.0}, {\"site\": 622, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04768066034349332, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08458828521741803, \"functional effect\": -1.0128, \"times_seen\": 9.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02403298556562894, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08598622452794193, \"functional effect\": -0.1853, \"times_seen\": 5.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.023656510892141002, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08887607143051594, \"functional effect\": -2.37, \"times_seen\": 1.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09097344216486859, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.09312135031127006, \"functional effect\": -0.8131, \"times_seen\": 6.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006896593252590546, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08701366241102794, \"functional effect\": -1.9877, \"times_seen\": 5.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0018586804348642012, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.0875433271996127, \"functional effect\": 0.0731, \"times_seen\": 20.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0202880675429706, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08620971573701867, \"functional effect\": -0.301, \"times_seen\": 33.0}, {\"site\": 623, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.11692941146848221, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08062398676789212, \"functional effect\": -0.1941, \"times_seen\": 52.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.14146035591348388, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.09643781018593096, \"functional effect\": -0.0542, \"times_seen\": 8.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.09007624800505447, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.09306345730134134, \"functional effect\": 0.2853, \"times_seen\": 32.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.044823102859420955, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.0901896348118942, \"functional effect\": -0.3528, \"times_seen\": 29.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.20747676726643444, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.10095323965907751, \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.00865592161629476, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08795675976086742, \"functional effect\": -0.1129, \"times_seen\": 25.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0003310396109942664, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08745067838807814, \"functional effect\": 0.3301, \"times_seen\": 1.0}, {\"site\": 624, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.002625791988592406, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08758988822117925, \"functional effect\": -1.169, \"times_seen\": 23.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.014727533171557616, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.08832770760464616, \"functional effect\": -0.1243, \"times_seen\": 4.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0017453160228836156, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.08732490814529048, \"functional effect\": -1.7745, \"times_seen\": 1.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.07983067144588377, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.092404890481487, \"functional effect\": 0.3651, \"times_seen\": 24.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06849355374817552, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.08337674103809212, \"functional effect\": -0.5072, \"times_seen\": 30.0}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 625, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.045778405822413215, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.0902493750583027, \"functional effect\": -0.0393, \"times_seen\": 4.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005629069529083085, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08709014451056256, \"functional effect\": 0.2464, \"times_seen\": 1.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009538252756599221, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08685448105520194, \"functional effect\": -2.3288, \"times_seen\": 3.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.010606442022148265, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08679019672376237, \"functional effect\": -2.041, \"times_seen\": 2.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03755066487851685, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08518431854101813, \"functional effect\": -0.1729, \"times_seen\": 6.0}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 626, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.010816245591603128, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08808856685036871, \"functional effect\": 0.0994, \"times_seen\": 4.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.003115503310379233, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08761962495660575, \"functional effect\": -0.4191, \"times_seen\": 13.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.024383264798576384, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08596535003137898, \"functional effect\": -2.566, \"times_seen\": 4.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.001511408923958603, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.0875222571577914, \"functional effect\": -3.0079, \"times_seen\": 1.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02697806015812921, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08581087385455956, \"functional effect\": -1.4567, \"times_seen\": 5.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0029061076949331408, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08760690859357306, \"functional effect\": -0.2781, \"times_seen\": 6.0}, {\"site\": 627, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.043601057159832556, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08482781956122551, \"functional effect\": -0.7566, \"times_seen\": 6.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04217170189976073, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08491190467310125, \"functional effect\": -1.2904, \"times_seen\": 14.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.012171218497271537, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.0881713381122278, \"functional effect\": -0.4117, \"times_seen\": 1.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03963341393518811, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08506143078505472, \"functional effect\": -0.6186, \"times_seen\": 17.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.030989235307447745, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08557262226350881, \"functional effect\": -0.7441, \"times_seen\": 10.0}, {\"site\": 628, \"wildtype\": \"P\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03530350446348224, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08959647917470809, \"functional effect\": -1.4315, \"times_seen\": 3.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.012312236233096225, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.0881799569331194, \"functional effect\": -0.2457, \"times_seen\": 23.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004866088544736216, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.08713621502180344, \"functional effect\": -0.5282, \"times_seen\": 20.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01881445036236712, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.08629781822455848, \"functional effect\": -0.2064, \"times_seen\": 46.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.019203578352353184, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.08860217500443693, \"functional effect\": 0.0444, \"times_seen\": 3.0}, {\"site\": 629, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0024005979130467736, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08728525358503679, \"functional effect\": -1.8527, \"times_seen\": 5.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.006239130330343687, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08705332518975475, \"functional effect\": -3.0486, \"times_seen\": 1.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010091089316500835, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08682120504573825, \"functional effect\": -3.1025, \"times_seen\": 1.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.009980436068030526, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08682786439961206, \"functional effect\": -2.6673, \"times_seen\": 2.0}, {\"site\": 630, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.022095676264467637, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08610176787173517, \"functional effect\": -1.3895, \"times_seen\": 7.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.519686977367173, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.06098487829052498, \"functional effect\": -0.1903, \"times_seen\": 4.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.038292285443671054, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08514054060738012, \"functional effect\": -0.1111, \"times_seen\": 10.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.010422676828023622, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08806453947179561, \"functional effect\": -0.2623, \"times_seen\": 4.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01031829531833824, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08680753289391414, \"functional effect\": -0.679, \"times_seen\": 2.0}, {\"site\": 631, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.01446481729302904, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08655839322576504, \"functional effect\": -2.2069, \"times_seen\": 1.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.02400546166195053, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08598786499877638, \"functional effect\": -0.3495, \"times_seen\": 8.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0010752283838676067, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08749579991356655, \"functional effect\": 0.0355, \"times_seen\": 33.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.023168462679935626, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08884601069655414, \"functional effect\": -0.5959, \"times_seen\": 15.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0389618774191911, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08510103385547374, \"functional effect\": 0.0208, \"times_seen\": 39.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.009495969728584148, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08800798987097098, \"functional effect\": 0.1798, \"times_seen\": 4.0}, {\"site\": 632, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02518862032175188, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.0859173749935438, \"functional effect\": -0.1222, \"times_seen\": 7.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.043035235790320876, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.08486109534379582, \"functional effect\": -0.4859, \"times_seen\": 13.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.008579633911242113, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.08795210885284407, \"functional effect\": -1.1597, \"times_seen\": 2.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005623485832358003, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.08709048157826013, \"functional effect\": -2.7835, \"times_seen\": 1.0}, {\"site\": 633, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02847887002024076, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.0891736460587669, \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04555035807853217, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08471328164271566, \"functional effect\": -0.3422, \"times_seen\": 14.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.002939592819619922, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08760894198401149, \"functional effect\": -1.0914, \"times_seen\": 6.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.008623796114674303, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08690955148376074, \"functional effect\": 0.0202, \"times_seen\": 4.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.009970185495882647, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08682848132725454, \"functional effect\": -2.5185, \"times_seen\": 2.0}, {\"site\": 634, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.005035623231965874, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08773631780569077, \"functional effect\": -0.1178, \"times_seen\": 4.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.054120563970127614, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08421154142197483, \"functional effect\": -0.7965, \"times_seen\": 30.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.07602162347211992, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.0829428093009691, \"functional effect\": 0.0897, \"times_seen\": 14.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02132961466687082, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08614749948586588, \"functional effect\": -0.0527, \"times_seen\": 7.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01190558515746708, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08815510523536108, \"functional effect\": 0.1727, \"times_seen\": 5.0}, {\"site\": 635, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.020639635326130494, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08618871000457333, \"functional effect\": -0.9815, \"times_seen\": 3.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.013770589963242564, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08660005529627224, \"functional effect\": -2.863, \"times_seen\": 2.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.014399606707179251, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08656230579976172, \"functional effect\": -0.9954, \"times_seen\": 16.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.009481813218928652, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08685787894769034, \"functional effect\": -2.3057, \"times_seen\": 1.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.5237411927346332, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.03040687055738157, \"functional effect\": -0.7301, \"times_seen\": 22.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.007764926526830799, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08696130614541382, \"functional effect\": -2.3083, \"times_seen\": 3.0}, {\"site\": 636, \"wildtype\": \"G\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.003729889194713828, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08720486647190992, \"functional effect\": -2.4438, \"times_seen\": 1.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.003899133403347812, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08719463696911285, \"functional effect\": -2.6987, \"times_seen\": 1.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.042355932060179374, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08490106223266684, \"functional effect\": -0.0979, \"times_seen\": 27.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0185266251535563, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08631503680834451, \"functional effect\": -1.0014, \"times_seen\": 34.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.06151777421714353, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08378086397976592, \"functional effect\": 0.0859, \"times_seen\": 27.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.009048207874017796, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08688398820832109, \"functional effect\": -0.1585, \"times_seen\": 7.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.014859314360141039, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08653472754240178, \"functional effect\": -0.5928, \"times_seen\": 33.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.04029170315139669, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08990680017295258, \"functional effect\": -0.2261, \"times_seen\": 44.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.13986150971611933, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.09633099355852275, \"functional effect\": -0.0838, \"times_seen\": 16.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.0002703507526687, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.17489399947602915, \"functional effect\": -0.3659, \"times_seen\": 19.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02046949694567275, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08619887491941837, \"functional effect\": 0.0309, \"times_seen\": 11.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03797887770600437, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08515903835085475, \"functional effect\": -0.485, \"times_seen\": 22.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013733623422179098, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08660227429988959, \"functional effect\": -0.0281, \"times_seen\": 8.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.054531456169385845, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08418756065161959, \"functional effect\": -0.1217, \"times_seen\": 59.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.8104875688893235, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.04985198556696513, \"functional effect\": -0.7143, \"times_seen\": 41.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.021912033810957385, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08876866926574947, \"functional effect\": 0.0478, \"times_seen\": 11.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.2526861619515512, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.07338333006366951, \"functional effect\": -0.2198, \"times_seen\": 43.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.3298783632191031, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.0695601080143686, \"functional effect\": -0.0095, \"times_seen\": 27.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03411417925162784, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08538746861818579, \"functional effect\": -0.0794, \"times_seen\": 18.0}, {\"site\": 637, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07084105665287954, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08324118363865252, \"functional effect\": -0.3701, \"times_seen\": 11.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0018901554235021352, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08754523713567566, \"functional effect\": -0.2823, \"times_seen\": 8.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.030313744028806697, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08928713262069676, \"functional effect\": 0.0799, \"times_seen\": 6.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.006167610431584076, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.0878051856950014, \"functional effect\": -0.6825, \"times_seen\": 1.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.00795962121243936, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08694957132876764, \"functional effect\": -0.1028, \"times_seen\": 13.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.5435001009977534, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.059986524003872506, \"functional effect\": -0.0317, \"times_seen\": 5.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.1512204214045139, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.09709243942257592, \"functional effect\": -0.065, \"times_seen\": 29.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 1.1798967769374311, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.1980832949873138, \"functional effect\": -0.1098, \"times_seen\": 17.0}, {\"site\": 638, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.5014045340445225, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.12376599415495146, \"functional effect\": 0.2456, \"times_seen\": 8.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.004889279672379164, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08772741849329328, \"functional effect\": -0.2545, \"times_seen\": 9.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.00733545569920137, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08698719720521159, \"functional effect\": -0.783, \"times_seen\": 2.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.13916356104216934, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.09628440171018404, \"functional effect\": -0.7632, \"times_seen\": 15.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.32568031682614795, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.10957287939012171, \"functional effect\": 0.0204, \"times_seen\": 16.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.015487276498053733, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08649706975175282, \"functional effect\": -0.2273, \"times_seen\": 20.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.07404542275865385, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.09203508616640856, \"functional effect\": -0.605, \"times_seen\": 6.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.07197780048196632, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08317562118061878, \"functional effect\": 0.1893, \"times_seen\": 13.0}, {\"site\": 639, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.046148814017769754, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.09027254932520275, \"functional effect\": -0.1246, \"times_seen\": 10.0}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.019606795238324086, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.08862694176736242, \"functional effect\": -0.0159, \"times_seen\": 14.0}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00830848791059048, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.08692854807597249, \"functional effect\": -2.1946, \"times_seen\": 1.0}, {\"site\": 640, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0077758209046150575, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.08696064946765597, \"functional effect\": -0.1933, \"times_seen\": 3.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0566955225338415, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08406137258737591, \"functional effect\": -0.2035, \"times_seen\": 17.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004886262152055708, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08713499658031364, \"functional effect\": -2.4358, \"times_seen\": 1.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.023693725486623556, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08600644718258141, \"functional effect\": -0.7004, \"times_seen\": 10.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03652483072280956, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08524491073555733, \"functional effect\": -2.2531, \"times_seen\": 10.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0056197607396021605, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08709070644944335, \"functional effect\": -0.2763, \"times_seen\": 1.0}, {\"site\": 641, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01463992899392962, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08654788756297105, \"functional effect\": -0.0797, \"times_seen\": 2.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0035073403473613648, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.0872183196542689, \"functional effect\": -2.343, \"times_seen\": 1.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02286328469419749, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.08605596826660725, \"functional effect\": -1.6248, \"times_seen\": 12.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.010240755789114014, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.0868121986035269, \"functional effect\": -2.5189, \"times_seen\": 2.0}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 642, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.06390588957152767, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.08364229494269484, \"functional effect\": -2.6014, \"times_seen\": 4.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.016210243439986474, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.0884185318723134, \"functional effect\": 0.2698, \"times_seen\": 17.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.036303425949342515, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08525799394297186, \"functional effect\": -0.115, \"times_seen\": 16.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.013379067825892514, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08824518759657801, \"functional effect\": -0.1284, \"times_seen\": 8.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.3902540835793006, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.11458867958676008, \"functional effect\": 0.2324, \"times_seen\": 19.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0009643873996673783, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08737218978034336, \"functional effect\": 0.0412, \"times_seen\": 11.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0021435736949505383, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08756061634657546, \"functional effect\": -0.2483, \"times_seen\": 1.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 2.2204543193430237, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.4074617856411136, \"functional effect\": 0.1537, \"times_seen\": 12.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0044028880305744585, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08716419600081234, \"functional effect\": 0.4244, \"times_seen\": 4.0}, {\"site\": 643, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0042353271077555515, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08768766194859283, \"functional effect\": -0.8314, \"times_seen\": 1.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.005116306540252037, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08774122463223723, \"functional effect\": -2.0077, \"times_seen\": 4.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.006431878511934801, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08782127103013194, \"functional effect\": -0.9453, \"times_seen\": 7.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008838558230224511, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08689661493831294, \"functional effect\": -1.0248, \"times_seen\": 17.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05121096966229856, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08438154870528958, \"functional effect\": -1.1521, \"times_seen\": 23.0}, {\"site\": 644, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.8750960469365348, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.02383435343269648, \"functional effect\": -0.6934, \"times_seen\": 34.0}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00395759652990068, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.08719110360435807, \"functional effect\": -3.0583, \"times_seen\": 1.0}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.03970999698834279, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.08987055634044445, \"functional effect\": -2.6399, \"times_seen\": 7.0}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 645, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.003678916792353618, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.08720794759435177, \"functional effect\": -2.8237, \"times_seen\": 1.0}, {\"site\": 646, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 646, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0013225142598078052, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": 0.08751079846095247, \"functional effect\": -2.3547, \"times_seen\": 3.0}, {\"site\": 647, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 647, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0475312218170997, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": 0.09035909102744957, \"functional effect\": -1.8481, \"times_seen\": 2.0}, {\"site\": 647, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.002118525361134622, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": 0.08730232107371719, \"functional effect\": -2.4623, \"times_seen\": 2.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.019984854628648706, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.08865016957169677, \"functional effect\": -1.436, \"times_seen\": 5.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.002515794578782674, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.087278284289052, \"functional effect\": -1.2201, \"times_seen\": 1.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.016680847744181704, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.08844737852930026, \"functional effect\": 0.0312, \"times_seen\": 16.0}, {\"site\": 648, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010189957940293672, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.08681525534833645, \"functional effect\": -2.371, \"times_seen\": 4.0}, {\"site\": 649, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 649, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.06216167836585528, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": 0.09128009002451394, \"functional effect\": -1.3668, \"times_seen\": 5.0}, {\"site\": 649, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.028045448316386487, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": 0.08914686008708401, \"functional effect\": -1.6485, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.021779256621368953, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08612065424604753, \"functional effect\": -2.8739, \"times_seen\": 4.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.03677193588668266, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08523031121647677, \"functional effect\": -1.62, \"times_seen\": 9.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.008451112347548109, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08691995476827018, \"functional effect\": -1.2756, \"times_seen\": 2.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0332021006598721, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08544146804508387, \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.015674131996650843, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08648586751842176, \"functional effect\": -2.7272, \"times_seen\": 2.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.004439552969895331, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08770007576816971, \"functional effect\": -2.3114, \"times_seen\": 7.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07033085609416681, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.0832706265962149, \"functional effect\": -1.9183, \"times_seen\": 4.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.011586920991684955, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08673123273588595, \"functional effect\": -3.1279, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04104597355102201, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08497818690085225, \"functional effect\": -2.5903, \"times_seen\": 8.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -6.137386103776925, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.001242013217867653, \"functional effect\": -2.4428, \"times_seen\": 5.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005860373639006691, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08707618265928539, \"functional effect\": -1.5743, \"times_seen\": 1.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.02276301863655994, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08606194928981246, \"functional effect\": -2.9389, \"times_seen\": 7.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.015049901862784206, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08834744654335591, \"functional effect\": -3.0575, \"times_seen\": 2.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -4.552010530150166, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.003727106647212166, \"functional effect\": -2.5286, \"times_seen\": 11.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.001181333987359176, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08735905209512845, \"functional effect\": -2.3997, \"times_seen\": 9.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.11054763483671243, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08098141778533229, \"functional effect\": -2.2728, \"times_seen\": 27.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04211906648136451, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.09002075113141136, \"functional effect\": -0.1762, \"times_seen\": 97.0}, {\"site\": 650, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.3460641186475857, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.0687840668452506, \"functional effect\": -2.8587, \"times_seen\": 3.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.049453492358303125, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.09047956720715293, \"functional effect\": -0.7878, \"times_seen\": 4.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03576716292618022, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08528969101459251, \"functional effect\": -0.375, \"times_seen\": 7.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.019615015180133685, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08624994405143012, \"functional effect\": -1.1807, \"times_seen\": 4.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0027883374598451933, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08726179790233422, \"functional effect\": -0.0612, \"times_seen\": 49.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05205212714377804, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08433236472583798, \"functional effect\": -0.0988, \"times_seen\": 16.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.009802997332455954, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08802672131241811, \"functional effect\": -0.0751, \"times_seen\": 7.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.001692619594121315, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08753325113955243, \"functional effect\": 0.1148, \"times_seen\": 5.0}, {\"site\": 651, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0011177259137632684, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08749837731907056, \"functional effect\": -0.0384, \"times_seen\": 26.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.0052123302903827025, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08774706475893329, \"functional effect\": -2.7181, \"times_seen\": 6.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05711521655099415, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08403692187326738, \"functional effect\": -1.7225, \"times_seen\": 23.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.002678651500770456, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08726843253930244, \"functional effect\": -1.9318, \"times_seen\": 1.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02014173902439037, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.0862184601905616, \"functional effect\": -1.3138, \"times_seen\": 3.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.02654062891355836, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08905392292297107, \"functional effect\": -2.9528, \"times_seen\": 1.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0044423142324579315, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08716181399620691, \"functional effect\": -0.1608, \"times_seen\": 15.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.047074525938324126, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.09033049170994104, \"functional effect\": -2.9483, \"times_seen\": 5.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.009857017031925696, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.0868352926290115, \"functional effect\": -0.9786, \"times_seen\": 25.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.031009014507725384, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08557144907972172, \"functional effect\": -1.8491, \"times_seen\": 7.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.009737498196198827, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08802272494231236, \"functional effect\": -1.7056, \"times_seen\": 7.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.10567868093251075, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08125518381439965, \"functional effect\": -1.0489, \"times_seen\": 17.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.06389842566472945, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08364272767441644, \"functional effect\": -1.0462, \"times_seen\": 16.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.24556456111513902, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.07374646903030226, \"functional effect\": -1.8558, \"times_seen\": 6.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.20369591479509483, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.07591803342168893, \"functional effect\": -1.6151, \"times_seen\": 12.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.018711334566158276, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08630398653179339, \"functional effect\": -2.7885, \"times_seen\": 5.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03214728154245914, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08550396098136917, \"functional effect\": -1.6506, \"times_seen\": 25.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03550961127172805, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08530491839201162, \"functional effect\": -2.3491, \"times_seen\": 12.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03113147728459195, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08933775576123941, \"functional effect\": -2.4896, \"times_seen\": 5.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.14044945990188068, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.07932024183968674, \"functional effect\": -1.3823, \"times_seen\": 18.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.03399063271585428, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08951498226977864, \"functional effect\": -0.2047, \"times_seen\": 17.0}, {\"site\": 652, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01319886434471865, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08823416579609558, \"functional effect\": -1.2286, \"times_seen\": 7.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02789793953837376, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08575617726836582, \"functional effect\": -0.6411, \"times_seen\": 10.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0305130011574331, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08929946532152819, \"functional effect\": -0.8782, \"times_seen\": 9.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.006493645816391342, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08782503107584837, \"functional effect\": -1.2335, \"times_seen\": 19.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03021953843606086, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08928130250941393, \"functional effect\": -0.3178, \"times_seen\": 6.0}, {\"site\": 653, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.04982688955555678, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08446254077944566, \"functional effect\": 0.0139, \"times_seen\": 40.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.02648101057350629, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08584044324122839, \"functional effect\": 0.0081, \"times_seen\": 8.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.009598845870498047, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08801426579555416, \"functional effect\": -0.2966, \"times_seen\": 12.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.009379719111438142, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.0868640257709287, \"functional effect\": -0.2064, \"times_seen\": 11.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.059456029555834324, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.0839006801778641, \"functional effect\": -0.0316, \"times_seen\": 13.0}, {\"site\": 654, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.6028393933581424, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.057569278950429806, \"functional effect\": -0.6074, \"times_seen\": 36.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.016271684816566247, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.0884222975135901, \"functional effect\": 0.3327, \"times_seen\": 29.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01580230198636521, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08647818439755693, \"functional effect\": 0.1507, \"times_seen\": 8.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.016291411608771733, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.088423506570366, \"functional effect\": 0.1099, \"times_seen\": 3.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.054699758586977176, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08417774004285955, \"functional effect\": -0.0312, \"times_seen\": 23.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.016501882237358382, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08643626024699637, \"functional effect\": 0.1005, \"times_seen\": 9.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 1.0500082120068457, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.18102872700702272, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01684227798000621, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08845727589473196, \"functional effect\": 0.0244, \"times_seen\": 1.0}, {\"site\": 655, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0005527864567388058, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08746412087031934, \"functional effect\": -0.0921, \"times_seen\": 12.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004314519954090767, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.0871695351529016, \"functional effect\": -0.6133, \"times_seen\": 5.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005236862946076126, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08711382378469676, \"functional effect\": -1.035, \"times_seen\": 1.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02995630788196919, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08563391169467063, \"functional effect\": -0.6814, \"times_seen\": 3.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04052581823521539, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08500883081637838, \"functional effect\": -0.324, \"times_seen\": 20.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.039572392582539175, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08506502868564442, \"functional effect\": -0.881, \"times_seen\": 13.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.02819774815282424, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08915627147929756, \"functional effect\": -0.081, \"times_seen\": 15.0}, {\"site\": 656, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04263725936585934, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08488450803530645, \"functional effect\": -0.666, \"times_seen\": 9.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.11699034712377623, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.09481589167954774, \"functional effect\": -0.0655, \"times_seen\": 17.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.19281326358341305, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.07649286967865773, \"functional effect\": -0.7964, \"times_seen\": 46.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009206897124128583, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.08687443192907193, \"functional effect\": -0.0063, \"times_seen\": 7.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.021318725414682892, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.08873217065232109, \"functional effect\": -1.6674, \"times_seen\": 6.0}, {\"site\": 657, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.02269832994514627, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08606580828948888, \"functional effect\": -0.4833, \"times_seen\": 7.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 1.163153093105448, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.1957976615060638, \"functional effect\": -0.2119, \"times_seen\": 32.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.007521778914348143, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.0869759635853294, \"functional effect\": -0.8207, \"times_seen\": 8.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.022564886553100925, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08880884822387022, \"functional effect\": -0.2801, \"times_seen\": 10.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.04879107641334779, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.0904380328920251, \"functional effect\": -0.1412, \"times_seen\": 5.0}, {\"site\": 658, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.02443873740125169, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08596204466892061, \"functional effect\": -0.2856, \"times_seen\": 10.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.014374654671517608, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08656380294528342, \"functional effect\": -2.6796, \"times_seen\": 1.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.011881599181472392, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08671351922613163, \"functional effect\": -2.0399, \"times_seen\": 2.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.020966748663744723, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08616916999107428, \"functional effect\": -1.9582, \"times_seen\": 1.0}, {\"site\": 659, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007797190490393687, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08695936139273878, \"functional effect\": -2.0971, \"times_seen\": 2.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.017258367292216165, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08639094880070443, \"functional effect\": -2.0284, \"times_seen\": 4.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.008325771028382552, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.0869275067004259, \"functional effect\": -2.1022, \"times_seen\": 3.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0010441857420460743, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08736735718378033, \"functional effect\": -2.0753, \"times_seen\": 1.0}, {\"site\": 660, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009877710994684331, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08683404707581202, \"functional effect\": -2.3828, \"times_seen\": 3.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.003796412662011161, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.08720084549992833, \"functional effect\": -2.5567, \"times_seen\": 1.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0020248038320415922, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.08755340821592779, \"functional effect\": -2.9382, \"times_seen\": 1.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0038263873996340317, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.08719903375507798, \"functional effect\": -2.7824, \"times_seen\": 2.0}, {\"site\": 661, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.047578357742435566, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.09036204329998537, \"functional effect\": -1.5756, \"times_seen\": 3.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.009933548810595234, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.08803468733312061, \"functional effect\": -0.2973, \"times_seen\": 2.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010394122448677184, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.08680297046530301, \"functional effect\": -2.3295, \"times_seen\": 2.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013760400285033057, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.08660066695000893, \"functional effect\": -1.8667, \"times_seen\": 3.0}, {\"site\": 662, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.028570792476597724, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.08571619110305659, \"functional effect\": -2.6498, \"times_seen\": 5.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.001999865097066868, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.0875518947620724, \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0187149923291648, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.088572173892886, \"functional effect\": -0.8916, \"times_seen\": 3.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.48476101946394534, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.12234638384001989, \"functional effect\": -2.9339, \"times_seen\": 5.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.003435994818283322, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.08763909162437941, \"functional effect\": -2.7603, \"times_seen\": 1.0}, {\"site\": 663, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.3506195435016536, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.11148348325979014, \"functional effect\": -0.2891, \"times_seen\": 24.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004763482890677983, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08714241244123196, \"functional effect\": -0.0997, \"times_seen\": 1.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.01164087305784431, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08813893162860578, \"functional effect\": -2.4207, \"times_seen\": 6.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02276627411419945, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08606175508907879, \"functional effect\": -1.6171, \"times_seen\": 4.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005905476138240799, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08707346046785806, \"functional effect\": -2.2662, \"times_seen\": 1.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.009086409470805865, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08688168760906254, \"functional effect\": -0.9965, \"times_seen\": 3.0}, {\"site\": 664, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01885502350453928, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08629539129141298, \"functional effect\": -2.5453, \"times_seen\": 3.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.016859010256214137, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.08641486626618135, \"functional effect\": -0.4449, \"times_seen\": 8.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.00832857495143495, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.08793680468726783, \"functional effect\": 0.3625, \"times_seen\": 4.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.001519368787944576, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.08752274005068619, \"functional effect\": -0.0976, \"times_seen\": 23.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.043220740055224686, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.08485018445643933, \"functional effect\": -1.6351, \"times_seen\": 10.0}, {\"site\": 665, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.48361874946895955, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.06252875475630032, \"functional effect\": -0.9117, \"times_seen\": 45.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.015380888765356813, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.0865034484847354, \"functional effect\": -2.698, \"times_seen\": 1.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004070520963727918, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08718427914014294, \"functional effect\": -2.4976, \"times_seen\": 1.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.017215731853084615, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08848017677632884, \"functional effect\": -1.2803, \"times_seen\": 8.0}, {\"site\": 666, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.031171460682787772, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08934023173603658, \"functional effect\": -1.3729, \"times_seen\": 1.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.13224759801289426, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.07977246940467804, \"functional effect\": 0.1047, \"times_seen\": 1.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03714005811573426, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.08971060829852472, \"functional effect\": -0.9151, \"times_seen\": 13.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0008665793988131599, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.08748314679612368, \"functional effect\": -2.6483, \"times_seen\": 1.0}, {\"site\": 667, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.5636960168647355, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.12922690393783423, \"functional effect\": -0.2114, \"times_seen\": 10.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.011503908309333752, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08673622339518053, \"functional effect\": -2.8933, \"times_seen\": 1.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.046761164736590304, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08464221438860949, \"functional effect\": -2.7944, \"times_seen\": 11.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.004817602549905639, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08713914353888223, \"functional effect\": -2.6835, \"times_seen\": 1.0}, {\"site\": 668, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0036075473077547947, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08721226183959957, \"functional effect\": -2.6498, \"times_seen\": 1.0}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04655437727685387, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.09029792986283407, \"functional effect\": -2.7888, \"times_seen\": 5.0}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.021490943806565927, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.08613786659427235, \"functional effect\": -1.3255, \"times_seen\": 19.0}, {\"site\": 669, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.013090675212171872, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.08822754927655008, \"functional effect\": -0.208, \"times_seen\": 58.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0048098532772352445, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08713961159815876, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0023381895966245203, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08728902946517268, \"functional effect\": -1.6065, \"times_seen\": 1.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.925826693447692, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.0460216223644456, \"functional effect\": -2.2149, \"times_seen\": 3.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.025864296925490103, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08901218444090034, \"functional effect\": -0.631, \"times_seen\": 5.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.027111341743102237, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08580294669000263, \"functional effect\": -2.7388, \"times_seen\": 6.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009542072474260133, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08685425109727832, \"functional effect\": -1.4861, \"times_seen\": 3.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.021201620666380663, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08615514271739821, \"functional effect\": -2.4918, \"times_seen\": 4.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00985308566479468, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08683552925689939, \"functional effect\": 0.2607, \"times_seen\": 6.0}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 670, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.09471253916133929, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08187516999414132, \"functional effect\": 0.2622, \"times_seen\": 56.0}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.07601263623419484, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.08294332599303642, \"functional effect\": -2.3616, \"times_seen\": 2.0}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.03205775274524601, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.08550926723396962, \"functional effect\": -0.2806, \"times_seen\": 21.0}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -1.0896833043353609, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.04108054244597283, \"functional effect\": -1.0209, \"times_seen\": 30.0}, {\"site\": 671, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0041130714183591505, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08718170778867737, \"functional effect\": 0.3023, \"times_seen\": 1.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.021920062235255104, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08876916325408657, \"functional effect\": -0.1829, \"times_seen\": 46.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0068896536289129, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08784914162674096, \"functional effect\": 0.0557, \"times_seen\": 36.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.013669981151261695, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08660609471017433, \"functional effect\": 0.0046, \"times_seen\": 72.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04902619647729903, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.09045277303341251, \"functional effect\": 0.2948, \"times_seen\": 9.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.05621439444626525, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.09090457670612694, \"functional effect\": -0.4375, \"times_seen\": 6.0}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 672, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.060096078305451626, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08386346606565422, \"functional effect\": 0.1768, \"times_seen\": 38.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.005037544263477686, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08712586001660722, \"functional effect\": -0.1647, \"times_seen\": 1.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.13639440033117195, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.07954350507793244, \"functional effect\": -0.1562, \"times_seen\": 26.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0366190462936934, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08523934397649756, \"functional effect\": 0.1508, \"times_seen\": 34.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.003345281734552649, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08763358126903888, \"functional effect\": 0.0301, \"times_seen\": 16.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.5277310257209651, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.060645790535020484, \"functional effect\": 0.2261, \"times_seen\": 10.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.011452251216665231, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08673932912523342, \"functional effect\": -0.4989, \"times_seen\": 1.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.5376840413565879, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.12691780560825855, \"functional effect\": 0.1098, \"times_seen\": 20.0}, {\"site\": 673, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.02591819346921624, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08587393742625275, \"functional effect\": -2.6388, \"times_seen\": 5.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.16433280666927172, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.07801793046940571, \"functional effect\": 0.0194, \"times_seen\": 59.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.051077533645305886, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.09058147737266947, \"functional effect\": -0.3555, \"times_seen\": 12.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03617838160941145, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08526538392582018, \"functional effect\": -0.0551, \"times_seen\": 21.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.026401842504230912, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08584515387544334, \"functional effect\": 0.0269, \"times_seen\": 60.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0017888544063642726, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08732227284963759, \"functional effect\": 0.0515, \"times_seen\": 12.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0015926035556016328, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.0875271830341579, \"functional effect\": -0.0279, \"times_seen\": 73.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.027887374115251887, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08913709291778647, \"functional effect\": 0.0435, \"times_seen\": 82.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0285364657067149, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08917720614578233, \"functional effect\": 0.4132, \"times_seen\": 18.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0804144629731693, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08269064214663606, \"functional effect\": -0.0347, \"times_seen\": 87.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03216839456927848, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08550270968836485, \"functional effect\": 0.115, \"times_seen\": 161.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.5788786056221179, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.05853339384480781, \"functional effect\": 0.1552, \"times_seen\": 40.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.011956582026312263, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08815822142670425, \"functional effect\": 0.1295, \"times_seen\": 22.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.09064433434130115, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08210637272289553, \"functional effect\": -0.0622, \"times_seen\": 109.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -3.7116272446694287, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.006673480512319179, \"functional effect\": 0.0838, \"times_seen\": 184.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.6386730960966205, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.05615698339745342, \"functional effect\": -0.0616, \"times_seen\": 72.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.3378876449710752, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.11050396118669453, \"functional effect\": 0.0604, \"times_seen\": 50.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.2959536438892841, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.10733823607379163, \"functional effect\": 0.2324, \"times_seen\": 52.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.043337106798774276, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08484334077764284, \"functional effect\": 0.1285, \"times_seen\": 28.0}, {\"site\": 674, \"wildtype\": \"Q\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.037303363508606385, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08519892176881091, \"functional effect\": 0.2683, \"times_seen\": 19.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.009032768190400638, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08688491804340716, \"functional effect\": -2.6582, \"times_seen\": 2.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.02275887110057634, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08882079025042787, \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01764739748230669, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08636765617453562, \"functional effect\": -0.1094, \"times_seen\": 54.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0008074101309425585, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08747955892241956, \"functional effect\": -0.4261, \"times_seen\": 11.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.012934358713194058, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08821799030940886, \"functional effect\": -0.028, \"times_seen\": 23.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.05663112880606175, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08406512469422797, \"functional effect\": 0.0433, \"times_seen\": 13.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.9817032966999676, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.04427324868291134, \"functional effect\": 0.0114, \"times_seen\": 24.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.03709905188024637, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08970805845815966, \"functional effect\": -0.1251, \"times_seen\": 33.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.001728133852215363, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08753540593779291, \"functional effect\": 0.0667, \"times_seen\": 17.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0004004272535844648, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08745488450383326, \"functional effect\": 0.065, \"times_seen\": 54.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02160589867295779, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08613100334723958, \"functional effect\": -0.0199, \"times_seen\": 19.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.051557608547757726, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08436127663705385, \"functional effect\": 0.1588, \"times_seen\": 37.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.011777686435039915, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.0867197651507324, \"functional effect\": 0.1123, \"times_seen\": 15.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.018233162058075847, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08854259756000515, \"functional effect\": 0.0573, \"times_seen\": 30.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.6162935574607789, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.13402517312536882, \"functional effect\": 0.082, \"times_seen\": 49.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.10397453595220289, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.09396432191696047, \"functional effect\": 0.084, \"times_seen\": 12.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.023561534424373136, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08601432813051475, \"functional effect\": -0.0321, \"times_seen\": 28.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05604275794373172, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08409941576458846, \"functional effect\": -0.0164, \"times_seen\": 81.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.04063090438936205, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08500263898407567, \"functional effect\": -0.0736, \"times_seen\": 34.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0021622699973743893, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08729967397902869, \"functional effect\": 0.0339, \"times_seen\": 1.0}, {\"site\": 675, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.020658705800406466, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08618757071410167, \"functional effect\": 0.1426, \"times_seen\": 15.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.01945857319812402, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08625929727121537, \"functional effect\": -2.5024, \"times_seen\": 7.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.02319735283361841, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08884778986715537, \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.050846617099915864, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08440286195252604, \"functional effect\": 0.0013, \"times_seen\": 41.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0020126862781196493, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08755267283619782, \"functional effect\": -0.348, \"times_seen\": 11.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.019142703874330324, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.088598436516945, \"functional effect\": 0.0777, \"times_seen\": 25.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.15483199686661764, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.09733580058836469, \"functional effect\": 0.1234, \"times_seen\": 61.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.016645056922938033, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08642768264052057, \"functional effect\": -0.031, \"times_seen\": 11.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.008045872642478028, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08791957477971564, \"functional effect\": 0.1033, \"times_seen\": 53.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.5610272003012088, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.059262165130277045, \"functional effect\": 0.1203, \"times_seen\": 19.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.16522276347212594, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.09803937585052817, \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.041061451980824885, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08497727518922402, \"functional effect\": 0.0434, \"times_seen\": 64.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.007258737647031708, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08699182303782693, \"functional effect\": 0.1142, \"times_seen\": 48.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.24603948020256186, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.07372219651204807, \"functional effect\": 0.0945, \"times_seen\": 45.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.26575113769375475, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.0727217742448359, \"functional effect\": 0.1529, \"times_seen\": 54.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.2842060417103614, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.10646774934211466, \"functional effect\": 0.2082, \"times_seen\": 41.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.39169991576801655, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.11470357500303535, \"functional effect\": -0.0367, \"times_seen\": 104.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.024947485142603615, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.0889556364577649, \"functional effect\": 0.0645, \"times_seen\": 92.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.4354776164369752, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.06465047275180308, \"functional effect\": 0.0274, \"times_seen\": 77.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03959794920477281, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08506352181448561, \"functional effect\": 0.0752, \"times_seen\": 50.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.012502531792796716, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08819158888617497, \"functional effect\": -0.1011, \"times_seen\": 23.0}, {\"site\": 676, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": 1.0439923500290935, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.18027543101044596, \"functional effect\": -0.0373, \"times_seen\": 36.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.038725480226398434, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08511497948725734, \"functional effect\": 0.05, \"times_seen\": 13.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00421252123475418, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.0871756982677734, \"functional effect\": -0.1612, \"times_seen\": 2.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.014195553367061225, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08829514362329938, \"functional effect\": 0.1095, \"times_seen\": 36.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.02923064784639117, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08567699546249348, \"functional effect\": 0.1538, \"times_seen\": 3.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 1.8640239135847865, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.3182662892350814, \"functional effect\": 0.2677, \"times_seen\": 13.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0041749915072921044, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08717796605317439, \"functional effect\": 0.0077, \"times_seen\": 1.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.03899397071358642, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08509914077198921, \"functional effect\": -0.0832, \"times_seen\": 12.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.07895186396081327, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.09234861983587662, \"functional effect\": -0.0819, \"times_seen\": 17.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3329197313918696, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.06941362171271472, \"functional effect\": -0.0276, \"times_seen\": 16.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.05279609729763326, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.09068944391129176, \"functional effect\": 0.0732, \"times_seen\": 10.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.06644798158799951, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.09155168999857355, \"functional effect\": -0.19, \"times_seen\": 8.0}, {\"site\": 677, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01119588149643439, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08675474424266066, \"functional effect\": -0.0183, \"times_seen\": 4.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.0013400227030222565, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08751186049215055, \"functional effect\": -2.9417, \"times_seen\": 2.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"A\", \"log2 fold change IC90\": -1.180796536356467, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.03856633361327419, \"functional effect\": -0.0278, \"times_seen\": 33.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.17207912653419374, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.0985064138307683, \"functional effect\": -0.056, \"times_seen\": 45.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": 1.508197875243945, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.24870031183105393, \"functional effect\": 0.2697, \"times_seen\": 49.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.05294183444822338, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08428037314913477, \"functional effect\": 0.0991, \"times_seen\": 16.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"F\", \"log2 fold change IC90\": 1.5953994942847542, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.2641962401814813, \"functional effect\": -0.0028, \"times_seen\": 26.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.036073709310060466, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.0852715704360055, \"functional effect\": 0.1376, \"times_seen\": 34.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.30746746634873723, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.07064909449583533, \"functional effect\": 0.0187, \"times_seen\": 20.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.06182644276440443, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09125888195210465, \"functional effect\": 0.062, \"times_seen\": 21.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0703160345803378, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09179748133557872, \"functional effect\": -0.0037, \"times_seen\": 114.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0473189568786424, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08460949532122057, \"functional effect\": 0.008, \"times_seen\": 17.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.5033020976745618, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.12392888954225405, \"functional effect\": -0.0425, \"times_seen\": 42.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006659186116769015, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08702798239104514, \"functional effect\": 0.1077, \"times_seen\": 60.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.04214249830151285, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08491362351053972, \"functional effect\": -0.0064, \"times_seen\": 41.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.29078433531386855, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.10695432154604824, \"functional effect\": -0.1568, \"times_seen\": 91.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04860844239272679, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09042658486200204, \"functional effect\": -0.0007, \"times_seen\": 119.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.026341121826766633, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08904160870561321, \"functional effect\": -0.0108, \"times_seen\": 58.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.19392999416043416, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.0764336826212324, \"functional effect\": -0.0938, \"times_seen\": 29.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.07087950251633399, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09183334133245476, \"functional effect\": -0.1172, \"times_seen\": 13.0}, {\"site\": 678, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0049708074469703096, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08773237617533292, \"functional effect\": -0.0357, \"times_seen\": 85.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.8969134073944226, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.16280261225674275, \"functional effect\": 0.3557, \"times_seen\": 72.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.010787700696358373, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.08808682396364186, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.07338938429521526, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.09199324445428386, \"functional effect\": 0.2684, \"times_seen\": 15.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": 2.221432464904696, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.4077381379310893, \"functional effect\": 0.3728, \"times_seen\": 25.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.051560590008054054, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.09061181177041445, \"functional effect\": 0.397, \"times_seen\": 7.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06674180178075875, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.08347804039362151, \"functional effect\": 0.2007, \"times_seen\": 13.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.7979492721990293, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.15200931288589428, \"functional effect\": 0.0544, \"times_seen\": 6.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.008246318871452036, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.08793179106315997, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": 1.1677119930264166, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.19641735849159886, \"functional effect\": 0.3201, \"times_seen\": 97.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.12859223092511382, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.09558145749701578, \"functional effect\": 0.1477, \"times_seen\": 20.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02010747513335897, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08622050789636372, \"functional effect\": -0.0466, \"times_seen\": 13.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.013646077696161826, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.086607529664886, \"functional effect\": -0.0351, \"times_seen\": 5.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.024322826780956458, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08891712876721972, \"functional effect\": -0.0149, \"times_seen\": 5.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.057850986901095, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.09100775732051317, \"functional effect\": -0.0824, \"times_seen\": 17.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005647116419623616, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08708905509358233, \"functional effect\": -0.2031, \"times_seen\": 6.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.6550703261871247, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.1376763511790222, \"functional effect\": -0.0267, \"times_seen\": 50.0}, {\"site\": 680, \"wildtype\": \"R\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.005473768338302468, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08776296728813823, \"functional effect\": -0.0464, \"times_seen\": 1.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02597940000562577, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08587029428987529, \"functional effect\": 0.2704, \"times_seen\": 8.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006781029576667827, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08702063271393344, \"functional effect\": 0.0403, \"times_seen\": 2.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.007675086771464331, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08696672158353991, \"functional effect\": -0.022, \"times_seen\": 17.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.016713485510427003, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08844937947713521, \"functional effect\": 0.0168, \"times_seen\": 60.0}, {\"site\": 681, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04143864202468501, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08997830426851525, \"functional effect\": 0.0507, \"times_seen\": 14.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.047092726558657795, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.09033163130029671, \"functional effect\": 0.4033, \"times_seen\": 35.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.468189063402139, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.2418981112306679, \"functional effect\": 0.4203, \"times_seen\": 24.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.06393683481181474, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.08364050086765981, \"functional effect\": 0.1163, \"times_seen\": 6.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.030307238964389395, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.0892867300288645, \"functional effect\": 0.3921, \"times_seen\": 7.0}, {\"site\": 682, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.030103333213000367, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.0892741114291419, \"functional effect\": -0.1572, \"times_seen\": 3.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02395774632521152, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.0888946307354078, \"functional effect\": 0.1162, \"times_seen\": 1.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.03285203257199372, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08944436335160182, \"functional effect\": -0.2995, \"times_seen\": 2.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.001892389252445572, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08754537268839499, \"functional effect\": 0.0832, \"times_seen\": 2.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.020364554325143246, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08867350428306925, \"functional effect\": 0.355, \"times_seen\": 11.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.026541023394148933, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08905394727326542, \"functional effect\": 0.4224, \"times_seen\": 13.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.002971425998091172, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08761087510346872, \"functional effect\": 0.1903, \"times_seen\": 5.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.004038984679955712, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08767572897839024, \"functional effect\": 0.0474, \"times_seen\": 3.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.016494919309173704, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08643667741826816, \"functional effect\": -0.0649, \"times_seen\": 6.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03730848362186321, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08972108205506112, \"functional effect\": 0.397, \"times_seen\": 2.0}, {\"site\": 683, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005151891896240898, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08711895471731979, \"functional effect\": 0.1546, \"times_seen\": 6.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0016559822826780664, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08753102825656445, \"functional effect\": 0.0484, \"times_seen\": 10.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.007326158990482487, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08787572550063776, \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.11310663368555379, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.09456099196654483, \"functional effect\": 0.1331, \"times_seen\": 24.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.011306947220358651, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08674806569500057, \"functional effect\": -0.1648, \"times_seen\": 11.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0253642703304479, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08590691507750038, \"functional effect\": 0.0449, \"times_seen\": 19.0}, {\"site\": 684, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.17000841592337787, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.0777116083269737, \"functional effect\": -0.2151, \"times_seen\": 18.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.06342895003836205, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08366995076092752, \"functional effect\": 0.1009, \"times_seen\": 28.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 1.968367570358918, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.34213792026614714, \"functional effect\": 0.2832, \"times_seen\": 13.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.017554630327729515, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08637320990493799, \"functional effect\": -0.4225, \"times_seen\": 6.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.039439195746382244, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.0850728826779455, \"functional effect\": 0.0176, \"times_seen\": 37.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.027951439429263297, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08914105128908616, \"functional effect\": 0.1275, \"times_seen\": 8.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.006553788682142612, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08703434053388659, \"functional effect\": -0.5499, \"times_seen\": 1.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01028785154263124, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.0868093647273024, \"functional effect\": -0.154, \"times_seen\": 1.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -2.3592700360413255, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.017039328716257116, \"functional effect\": -0.064, \"times_seen\": 14.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.023657273076910724, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08600862032504725, \"functional effect\": -0.099, \"times_seen\": 7.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.00688141384322846, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08784863988797294, \"functional effect\": 0.0169, \"times_seen\": 4.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.07550114214052327, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.09212799899349533, \"functional effect\": 0.0709, \"times_seen\": 20.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.019106164511643608, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08628037049724664, \"functional effect\": 0.2707, \"times_seen\": 7.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.009498895214205197, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08800816833305941, \"functional effect\": 0.0171, \"times_seen\": 26.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.024523517835454034, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08892949875053088, \"functional effect\": -0.0361, \"times_seen\": 74.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -2.009711847752139, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.02171100768876799, \"functional effect\": -0.0197, \"times_seen\": 65.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0009539532147532613, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08737282169551285, \"functional effect\": 0.0917, \"times_seen\": 90.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.03411830967625227, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08952290460004554, \"functional effect\": -0.1542, \"times_seen\": 7.0}, {\"site\": 685, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.020852702314293453, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08617598201123938, \"functional effect\": -0.2307, \"times_seen\": 9.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.009580329788537413, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08801313619515, \"functional effect\": -0.3588, \"times_seen\": 3.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.030085951668435612, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08562621678657058, \"functional effect\": 0.0158, \"times_seen\": 9.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.018997415240020864, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08858951453597425, \"functional effect\": -0.1987, \"times_seen\": 20.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04816162511990971, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08456008992757036, \"functional effect\": 0.0178, \"times_seen\": 46.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.7369517681342383, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.14571629407444395, \"functional effect\": 0.0532, \"times_seen\": 40.0}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 686, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006679949507915501, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08702672988584848, \"functional effect\": 0.2043, \"times_seen\": 4.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0030921115680234068, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08724342597789475, \"functional effect\": -2.8604, \"times_seen\": 1.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0011361759602720174, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08749949630777426, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.015989118956454017, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08646698691924862, \"functional effect\": 0.2871, \"times_seen\": 23.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.008149771814481304, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08693811192581916, \"functional effect\": -0.3511, \"times_seen\": 34.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.011667012552145323, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08672641796439196, \"functional effect\": -0.041, \"times_seen\": 5.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.041185066934395075, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08996249063434321, \"functional effect\": 0.0963, \"times_seen\": 29.0}, {\"site\": 687, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.024707142300925303, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08894081830903891, \"functional effect\": 0.155, \"times_seen\": 4.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0350462220200378, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08533232247271959, \"functional effect\": -0.1149, \"times_seen\": 9.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0019566357107042476, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08731211810971186, \"functional effect\": 0.0782, \"times_seen\": 1.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.2989879250553563, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.10756422779061195, \"functional effect\": -0.8101, \"times_seen\": 8.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.1249568455091563, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08017662508076887, \"functional effect\": -0.682, \"times_seen\": 35.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.02610772218516587, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08586265679686977, \"functional effect\": 0.1487, \"times_seen\": 6.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009320337962255067, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08686760115705071, \"functional effect\": -0.0558, \"times_seen\": 4.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07971211895393104, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.0827309080485922, \"functional effect\": 0.0284, \"times_seen\": 26.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0434653518287051, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.09010479535401017, \"functional effect\": -0.8109, \"times_seen\": 15.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0029835618202517142, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08724999050324525, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.012603317172763114, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08819775008658091, \"functional effect\": -0.0433, \"times_seen\": 8.0}, {\"site\": 688, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07095369739055427, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08323468470295438, \"functional effect\": -0.498, \"times_seen\": 25.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.008363412197729117, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08692523871570088, \"functional effect\": -0.0477, \"times_seen\": 4.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0448340601014023, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.09019031980309306, \"functional effect\": -0.3436, \"times_seen\": 3.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.022011653800691783, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08610678257902879, \"functional effect\": -0.636, \"times_seen\": 6.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01293812439109422, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08821822057357463, \"functional effect\": -2.4933, \"times_seen\": 3.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0006484469132968145, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08746992052644456, \"functional effect\": -2.0274, \"times_seen\": 1.0}, {\"site\": 689, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.016696749246772235, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08844835340890403, \"functional effect\": -1.4086, \"times_seen\": 2.0}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0014867843763073235, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.08752076330251497, \"functional effect\": -0.3145, \"times_seen\": 6.0}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.034418944968967455, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.08954156173011445, \"functional effect\": -1.368, \"times_seen\": 1.0}, {\"site\": 690, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.039817441261825945, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.08987724967197706, \"functional effect\": -0.1459, \"times_seen\": 19.0}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02875063619937249, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.08570550654555975, \"functional effect\": -2.0572, \"times_seen\": 14.0}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.031996684401376464, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.08551288686231036, \"functional effect\": -1.6896, \"times_seen\": 13.0}, {\"site\": 691, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.010183648140635196, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.08681563504609026, \"functional effect\": 0.1418, \"times_seen\": 21.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.00013871583789412372, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08742220823731824, \"functional effect\": -0.8277, \"times_seen\": 5.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01723035388984681, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08639262630553911, \"functional effect\": -0.1373, \"times_seen\": 14.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.027239372681167388, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08579533250681809, \"functional effect\": -0.2243, \"times_seen\": 7.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.004914574973769328, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08772895666378827, \"functional effect\": -1.8929, \"times_seen\": 3.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.02478692112631087, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08894573673601328, \"functional effect\": -0.2672, \"times_seen\": 1.0}, {\"site\": 693, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.3509018488714098, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.06855380233362234, \"functional effect\": -0.307, \"times_seen\": 45.0}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01350282861640802, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.08661612958692626, \"functional effect\": -0.48, \"times_seen\": 7.0}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.030588946095189633, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.08559636848086127, \"functional effect\": -2.7727, \"times_seen\": 4.0}, {\"site\": 694, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.010513077559191229, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.08807005785784604, \"functional effect\": -1.9839, \"times_seen\": 2.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0019383945080118537, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08731322207698673, \"functional effect\": -0.6287, \"times_seen\": 1.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005524694749341404, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.0870964454565139, \"functional effect\": -0.3265, \"times_seen\": 1.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.05285735694496875, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08428530835979975, \"functional effect\": -0.3187, \"times_seen\": 4.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011123799569512208, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08675907891158359, \"functional effect\": -1.1388, \"times_seen\": 3.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010395330738407456, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08680289776588222, \"functional effect\": -0.1677, \"times_seen\": 2.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.008766681132037924, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08690094435786368, \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 695, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04829858157947481, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08455206293605386, \"functional effect\": -0.3115, \"times_seen\": 10.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013892479882861603, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08659273896982735, \"functional effect\": -0.5968, \"times_seen\": 3.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.018810276999753274, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08629806786332408, \"functional effect\": -1.1541, \"times_seen\": 7.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.029822718927799707, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.0892567486781386, \"functional effect\": -2.2536, \"times_seen\": 1.0}, {\"site\": 696, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.006038282734417041, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.0870654453313707, \"functional effect\": -1.0615, \"times_seen\": 2.0}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0031882880359741157, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.08762404552439866, \"functional effect\": -2.1499, \"times_seen\": 1.0}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01565617774903527, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.08648694383621511, \"functional effect\": -2.9319, \"times_seen\": 11.0}, {\"site\": 697, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.006886071303836412, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.08701429702652848, \"functional effect\": -2.4878, \"times_seen\": 2.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.01626967936838599, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08645017334874791, \"functional effect\": -2.4326, \"times_seen\": 4.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.048412677296119665, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08454537639005284, \"functional effect\": -0.3332, \"times_seen\": 18.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.042776393831644256, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08487632211183475, \"functional effect\": 0.1895, \"times_seen\": 13.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0008149723668334366, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08738123909033237, \"functional effect\": 0.3037, \"times_seen\": 36.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02821250833608661, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08573748081759251, \"functional effect\": -1.6567, \"times_seen\": 6.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.2218145058308514, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.10196153140145123, \"functional effect\": -0.5186, \"times_seen\": 45.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.029265778736638094, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08922229851694324, \"functional effect\": -0.3038, \"times_seen\": 15.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.029594051334601336, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08565541682176425, \"functional effect\": -1.6607, \"times_seen\": 4.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.00041875574794382074, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08745599556784467, \"functional effect\": 0.269, \"times_seen\": 16.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.04234306072049437, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.09003472892610552, \"functional effect\": -2.1994, \"times_seen\": 10.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.9450276151166195, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.02270658776216436, \"functional effect\": -1.2184, \"times_seen\": 11.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.010823671195711225, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08677712955235585, \"functional effect\": -0.1154, \"times_seen\": 16.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.13025026226324254, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.09569136856479121, \"functional effect\": 0.2828, \"times_seen\": 43.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0053895423498912425, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08710460507766804, \"functional effect\": 0.1819, \"times_seen\": 16.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.30324353104116175, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.10788198500957506, \"functional effect\": 0.0393, \"times_seen\": 51.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.9554173816386203, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.16954025038727566, \"functional effect\": 0.1561, \"times_seen\": 71.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07019420739550719, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.09178972990077489, \"functional effect\": -0.0478, \"times_seen\": 78.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.8216987951135444, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.024733042830496585, \"functional effect\": -0.3771, \"times_seen\": 68.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0029994761488133493, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08761257852801271, \"functional effect\": -1.306, \"times_seen\": 9.0}, {\"site\": 698, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04670911137688593, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08464526838892963, \"functional effect\": -1.6371, \"times_seen\": 6.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.002811566344236528, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08760116780715581, \"functional effect\": -0.9622, \"times_seen\": 6.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03609662986927024, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08527021570995591, \"functional effect\": -0.0147, \"times_seen\": 23.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.026014535548762298, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08586820302137808, \"functional effect\": -1.3361, \"times_seen\": 5.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.002368461238916, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.17514853274786912, \"functional effect\": -1.9836, \"times_seen\": 23.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.21133846756175761, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.07551692752597068, \"functional effect\": -1.0118, \"times_seen\": 29.0}, {\"site\": 699, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01888452045232986, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08858258243816579, \"functional effect\": -0.4209, \"times_seen\": 9.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.02540346953980244, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08898375660232331, \"functional effect\": -1.3029, \"times_seen\": 2.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.06583807194187269, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.0915129940469562, \"functional effect\": 0.2062, \"times_seen\": 5.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.00422525910649202, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08717492857776296, \"functional effect\": 0.1572, \"times_seen\": 3.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0006153688665036458, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08739332952338286, \"functional effect\": 0.2645, \"times_seen\": 8.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.029828880177000985, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08925712986351056, \"functional effect\": 0.2939, \"times_seen\": 13.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.024530057118201595, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08892990184088499, \"functional effect\": 0.2507, \"times_seen\": 31.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07723303640392683, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.09223866116176041, \"functional effect\": 0.3242, \"times_seen\": 21.0}, {\"site\": 700, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.015394776720331793, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08650261577222074, \"functional effect\": 0.3651, \"times_seen\": 11.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.00047244935923449225, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08745925052851393, \"functional effect\": -0.0676, \"times_seen\": 3.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0020480534527472657, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08730658566967421, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.7165759245039043, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.14367274102064048, \"functional effect\": 0.3483, \"times_seen\": 21.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.05038233926406796, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08443002825101101, \"functional effect\": -1.5507, \"times_seen\": 15.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.007270582555284737, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08787234036007949, \"functional effect\": 0.3651, \"times_seen\": 7.0}, {\"site\": 701, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.5955015866306643, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.057862832568656125, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0196038628118479, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.0862506107861393, \"functional effect\": -2.517, \"times_seen\": 2.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02248288231987754, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.08607866205144758, \"functional effect\": -2.0341, \"times_seen\": 5.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02390396977963255, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.08889131724438484, \"functional effect\": 0.2691, \"times_seen\": 20.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.5348534517302023, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.06034712680959515, \"functional effect\": -0.0799, \"times_seen\": 40.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0014338841104112243, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.08734376084661688, \"functional effect\": -1.7662, \"times_seen\": 4.0}, {\"site\": 702, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.02305173625376921, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08604472796853885, \"functional effect\": -1.7527, \"times_seen\": 4.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.021521475247565185, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08613604369664725, \"functional effect\": -1.2316, \"times_seen\": 2.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.12064448895184626, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08041663938796159, \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01029082390504535, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08805649131468936, \"functional effect\": -1.5893, \"times_seen\": 12.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02365854709026051, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08600854437269488, \"functional effect\": -1.6831, \"times_seen\": 4.0}, {\"site\": 703, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.709002291095923, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.02674253529635696, \"functional effect\": -2.1539, \"times_seen\": 3.0}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005452421294167948, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.08710080876167703, \"functional effect\": -2.6432, \"times_seen\": 1.0}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.00017097771240541154, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.08742025330388, \"functional effect\": -2.3384, \"times_seen\": 1.0}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004740145104692888, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.08714382211365988, \"functional effect\": -2.1444, \"times_seen\": 1.0}, {\"site\": 704, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.007728909880982872, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08696347714730478, \"functional effect\": -0.8247, \"times_seen\": 4.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.012969800187810871, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08664813731421797, \"functional effect\": -2.8552, \"times_seen\": 3.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.018643610935922747, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08856779164397756, \"functional effect\": -2.5027, \"times_seen\": 5.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.034565809220576345, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.0895506773945133, \"functional effect\": -0.5849, \"times_seen\": 17.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.003663721638716811, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08720886611496978, \"functional effect\": -1.0821, \"times_seen\": 16.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.009601411199931749, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08685067881454002, \"functional effect\": -2.0092, \"times_seen\": 2.0}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 705, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005470119056667167, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08709974028918044, \"functional effect\": 0.2883, \"times_seen\": 3.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0028433920938598744, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08725846797151296, \"functional effect\": -1.1873, \"times_seen\": 1.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.007535319919618188, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08697514724062673, \"functional effect\": 0.2955, \"times_seen\": 2.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.014498467774361338, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.0883136843948243, \"functional effect\": -1.7003, \"times_seen\": 4.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.020442447820572602, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.0862004910794126, \"functional effect\": -1.7224, \"times_seen\": 6.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.09839030808233037, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08166671674326337, \"functional effect\": -2.0355, \"times_seen\": 13.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.012405004450537731, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08818562726551633, \"functional effect\": -2.0548, \"times_seen\": 7.0}, {\"site\": 706, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018677810620831292, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08630599200326138, \"functional effect\": -1.5874, \"times_seen\": 14.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03442001963820242, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.0853693690421962, \"functional effect\": 0.1446, \"times_seen\": 40.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.03772059929267291, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08974671515458547, \"functional effect\": -0.4409, \"times_seen\": 16.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.011860084904981765, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08671481235633972, \"functional effect\": -1.1788, \"times_seen\": 1.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.11154283787333322, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.09445854899375335, \"functional effect\": -0.7601, \"times_seen\": 12.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05232403697412738, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08431647180491766, \"functional effect\": 0.0623, \"times_seen\": 8.0}, {\"site\": 707, \"wildtype\": \"N\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01781926014620861, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08635736814348076, \"functional effect\": -0.2966, \"times_seen\": 5.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.03370814295703661, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08949745632735497, \"functional effect\": -1.6379, \"times_seen\": 7.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009446755703802967, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08685998962133655, \"functional effect\": -2.7301, \"times_seen\": 1.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.08047524932757444, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08268715814159942, \"functional effect\": -0.1169, \"times_seen\": 8.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01632373121651998, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08644693447707058, \"functional effect\": -1.7186, \"times_seen\": 2.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004141853636863483, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08717996850361594, \"functional effect\": -2.5205, \"times_seen\": 1.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.06059237998351509, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08383462114732007, \"functional effect\": -1.7215, \"times_seen\": 17.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.014047816228138131, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08658341594929779, \"functional effect\": -1.0857, \"times_seen\": 4.0}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 708, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02256108775276001, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08607399603653702, \"functional effect\": -1.4944, \"times_seen\": 6.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005602729044849477, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08709173460233885, \"functional effect\": -1.5703, \"times_seen\": 1.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.001402736027277101, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08751566467724395, \"functional effect\": -2.8567, \"times_seen\": 1.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02698581495781911, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08581041260368488, \"functional effect\": -0.9693, \"times_seen\": 9.0}, {\"site\": 709, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.021852811096942287, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08611626357587714, \"functional effect\": -1.6063, \"times_seen\": 26.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.07854768216939303, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.09232275130406369, \"functional effect\": -0.4359, \"times_seen\": 16.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.017670843723673297, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08850809309253613, \"functional effect\": -0.5815, \"times_seen\": 1.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.002396116388509558, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08757594510892791, \"functional effect\": -2.866, \"times_seen\": 1.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03413140980046344, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08952371749983469, \"functional effect\": -0.2114, \"times_seen\": 6.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.025872998397511737, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.0890127213106797, \"functional effect\": -2.0541, \"times_seen\": 10.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0041034467067550115, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08767964656408762, \"functional effect\": -2.1178, \"times_seen\": 11.0}, {\"site\": 710, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.012004278890956099, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08670614584731137, \"functional effect\": -2.4829, \"times_seen\": 2.0}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.004481333488609553, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.08715945664204733, \"functional effect\": -2.012, \"times_seen\": 1.0}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.003805202344820118, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.08720031422657117, \"functional effect\": -2.5336, \"times_seen\": 1.0}, {\"site\": 711, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.033078152973330006, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.08945838348741918, \"functional effect\": 0.4407, \"times_seen\": 11.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0052492325534958875, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08711307687758817, \"functional effect\": -2.8988, \"times_seen\": 2.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004324568820807641, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08716892798924952, \"functional effect\": -2.9818, \"times_seen\": 1.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.012321544153086906, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08818052585074118, \"functional effect\": -2.0135, \"times_seen\": 10.0}, {\"site\": 712, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0026469461023338205, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08759117255361953, \"functional effect\": -2.5409, \"times_seen\": 1.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0033097937817080157, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08723026317573068, \"functional effect\": -2.766, \"times_seen\": 3.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004698958998479244, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08714630993391523, \"functional effect\": -1.3536, \"times_seen\": 42.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.08867267146707396, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08221866031914579, \"functional effect\": -0.1522, \"times_seen\": 28.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.009190532544530125, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08687541735674661, \"functional effect\": -2.9938, \"times_seen\": 2.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0273352643683188, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08578963013345262, \"functional effect\": -0.7254, \"times_seen\": 7.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.007620347285415301, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08789364657551074, \"functional effect\": -1.8224, \"times_seen\": 9.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03886669674036613, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08510664851494237, \"functional effect\": -1.142, \"times_seen\": 27.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0867894679373197, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08232605347328949, \"functional effect\": -0.9137, \"times_seen\": 22.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.060980377080641926, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.09120537904922271, \"functional effect\": -2.3512, \"times_seen\": 32.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.042931734269141285, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.0848671836488629, \"functional effect\": -0.6421, \"times_seen\": 12.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07729184465876215, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08286981442398784, \"functional effect\": 0.1647, \"times_seen\": 50.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.027994105712782245, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.085750461182557, \"functional effect\": 0.1258, \"times_seen\": 8.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.030149842905228822, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.0892769894998759, \"functional effect\": -1.3337, \"times_seen\": 16.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.015336705148744282, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.0865060977582285, \"functional effect\": -2.6193, \"times_seen\": 2.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.024697304647025114, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08594663948847418, \"functional effect\": -0.5219, \"times_seen\": 19.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.002572047302202919, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08758662529779145, \"functional effect\": -0.2702, \"times_seen\": 54.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.4599291771181401, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.12025856247661815, \"functional effect\": -0.3731, \"times_seen\": 75.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.08719326819662769, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.09287767155782863, \"functional effect\": -2.65, \"times_seen\": 12.0}, {\"site\": 713, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012300928794123138, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08668831898523616, \"functional effect\": -2.5844, \"times_seen\": 3.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.013363157869797028, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08662451550686738, \"functional effect\": -2.3437, \"times_seen\": 4.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.017683503669100285, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08850886977264731, \"functional effect\": -2.098, \"times_seen\": 7.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.015682995579816096, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.0864853361709763, \"functional effect\": -2.5413, \"times_seen\": 6.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.042072558125417284, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08491774012394039, \"functional effect\": -1.7257, \"times_seen\": 18.0}, {\"site\": 714, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0075754991856972495, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08789091432673599, \"functional effect\": -1.0141, \"times_seen\": 7.0}, {\"site\": 715, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 715, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.022611762906758294, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": 0.08881173386670747, \"functional effect\": -2.6831, \"times_seen\": 1.0}, {\"site\": 715, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007520318513417667, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": 0.08697605162877506, \"functional effect\": -2.4214, \"times_seen\": 1.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.003997233399675798, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.08718870813279515, \"functional effect\": -2.2291, \"times_seen\": 2.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04492904890870691, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.08474977201128643, \"functional effect\": -2.5731, \"times_seen\": 9.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.03724870673531329, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.08971736461257895, \"functional effect\": -1.5682, \"times_seen\": 12.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.09260769737140376, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.09322689602627192, \"functional effect\": -0.1762, \"times_seen\": 47.0}, {\"site\": 716, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.00032579251421668436, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.08745036032963521, \"functional effect\": -1.3054, \"times_seen\": 1.0}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.003962767434990461, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.0871907910947142, \"functional effect\": -1.6882, \"times_seen\": 1.0}, {\"site\": 717, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.043099156832102296, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.09008192722386557, \"functional effect\": -1.9977, \"times_seen\": 5.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.010341055713462123, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.0880595573221832, \"functional effect\": -1.3676, \"times_seen\": 4.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.008060951710967464, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08694346447059545, \"functional effect\": -0.8207, \"times_seen\": 2.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005032162574944615, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08712618502300361, \"functional effect\": -2.3019, \"times_seen\": 1.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.009127042158648829, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08687924067004996, \"functional effect\": -2.8793, \"times_seen\": 2.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.011439045031172929, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08812660216056557, \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 718, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004193900573750094, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08717682343945204, \"functional effect\": -1.6519, \"times_seen\": 3.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.002470958226777686, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.08758048835233356, \"functional effect\": -1.1452, \"times_seen\": 1.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0030692556598651047, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.08761681622937688, \"functional effect\": -2.3651, \"times_seen\": 1.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.0493098239331577, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.18094111479222824, \"functional effect\": -0.1681, \"times_seen\": 7.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.004328267226843652, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.08769331107333882, \"functional effect\": -1.12, \"times_seen\": 1.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.015420690934607519, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.0865010619946555, \"functional effect\": -0.9729, \"times_seen\": 5.0}, {\"site\": 719, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.03563911308950378, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08529726144034692, \"functional effect\": 0.1971, \"times_seen\": 5.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.06615642804486188, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08351191849397527, \"functional effect\": -0.552, \"times_seen\": 21.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005327996226203167, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08710832108486158, \"functional effect\": 0.3561, \"times_seen\": 4.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.005431358432734109, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08710208041341631, \"functional effect\": -1.8336, \"times_seen\": 1.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.007105834098272981, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08700104332553388, \"functional effect\": -0.1125, \"times_seen\": 2.0}, {\"site\": 720, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005667246490061054, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08708783993962874, \"functional effect\": -1.4441, \"times_seen\": 1.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.024857099592772536, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08895006351821447, \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.16964436074697872, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.09834030958137709, \"functional effect\": -0.3543, \"times_seen\": 22.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.009685747301032162, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08684560190408004, \"functional effect\": 0.106, \"times_seen\": 2.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.00037070805305068616, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.0874530829710031, \"functional effect\": -0.394, \"times_seen\": 1.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00039148037151669196, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08740689294376756, \"functional effect\": -0.3071, \"times_seen\": 16.0}, {\"site\": 721, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 722, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.025660226303794664, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": 0.0858892938503487, \"functional effect\": 0.0546, \"times_seen\": 4.0}, {\"site\": 722, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.005675204787988903, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.08777522205736754, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.5032952924213653, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.1239283049658476, \"functional effect\": 0.3018, \"times_seen\": 8.0}, {\"site\": 723, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.012533423142879857, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.08819347728693673, \"functional effect\": -0.9196, \"times_seen\": 4.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0313645846000629, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08935219191466519, \"functional effect\": 0.0311, \"times_seen\": 4.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.022356025337859946, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08608623132913641, \"functional effect\": -0.4216, \"times_seen\": 5.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006970834666135288, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08700918478346432, \"functional effect\": -2.1136, \"times_seen\": 2.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.07201098936157911, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.0919053932715748, \"functional effect\": -1.2101, \"times_seen\": 4.0}, {\"site\": 724, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.001392266014075047, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08734628052914312, \"functional effect\": -0.4228, \"times_seen\": 1.0}, {\"site\": 725, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.032744938976926395, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": 0.08546854705598625, \"functional effect\": -2.5579, \"times_seen\": 2.0}, {\"site\": 725, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 725, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.014136895953699902, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": 0.088291553772843, \"functional effect\": -1.3273, \"times_seen\": 19.0}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.016470470716884355, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.0864381422274838, \"functional effect\": 0.3624, \"times_seen\": 1.0}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.016615397439253627, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.08642945947257473, \"functional effect\": -2.8092, \"times_seen\": 1.0}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.6049473787889191, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.05748522335843395, \"functional effect\": -2.6593, \"times_seen\": 4.0}, {\"site\": 726, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.003773562663634328, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08720222663377927, \"functional effect\": -0.3591, \"times_seen\": 1.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.03384105268023057, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08540363544042308, \"functional effect\": -0.2728, \"times_seen\": 20.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0013385708241492422, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08751177242325599, \"functional effect\": -3.0775, \"times_seen\": 2.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.025781971283420003, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08900710521351606, \"functional effect\": -0.6208, \"times_seen\": 2.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0009365320848827015, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08748738873866677, \"functional effect\": -2.1699, \"times_seen\": 3.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005141977883313838, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08711955338951759, \"functional effect\": -1.1008, \"times_seen\": 1.0}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 727, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.008464162858144214, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08794506958541584, \"functional effect\": -0.5495, \"times_seen\": 2.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.3058252315791111, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.07072956088405223, \"functional effect\": -1.1321, \"times_seen\": 36.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.0745592379532414, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.18413574051784504, \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.002363158204392816, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.08757394447048912, \"functional effect\": -2.2466, \"times_seen\": 5.0}, {\"site\": 728, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01846909731757933, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.08855707881100595, \"functional effect\": -1.9343, \"times_seen\": 7.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01857155556944317, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.08631234870725446, \"functional effect\": 0.2513, \"times_seen\": 37.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.15775859298133782, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.09753345268661827, \"functional effect\": 0.2091, \"times_seen\": 44.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.018073001454099596, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.08634218093894293, \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06814514613141712, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.08339687876556907, \"functional effect\": 0.2056, \"times_seen\": 32.0}, {\"site\": 729, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.004747398058087384, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.08714338401102993, \"functional effect\": -2.8693, \"times_seen\": 1.0}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009767599552177415, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.08684067480156196, \"functional effect\": -2.9305, \"times_seen\": 1.0}, {\"site\": 730, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.18571532005047808, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.0768701357417873, \"functional effect\": -0.7708, \"times_seen\": 18.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05066217822590615, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08441365298146972, \"functional effect\": -0.4737, \"times_seen\": 13.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.017008562690735918, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08640590880570208, \"functional effect\": -0.9347, \"times_seen\": 4.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.020318747735084904, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08867068888115665, \"functional effect\": 0.2248, \"times_seen\": 32.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.011010657766955085, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08676588316557753, \"functional effect\": -2.7603, \"times_seen\": 2.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.007991050063652754, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.0869476771686734, \"functional effect\": -1.162, \"times_seen\": 1.0}, {\"site\": 731, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.10426473513935601, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08133485882605589, \"functional effect\": -0.0825, \"times_seen\": 28.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.029916630697480448, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08563626684190487, \"functional effect\": -0.7428, \"times_seen\": 6.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009445905200426515, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08686004082740169, \"functional effect\": -1.1909, \"times_seen\": 3.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.1928904615846233, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.09993769874700847, \"functional effect\": -1.0983, \"times_seen\": 20.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012041595595586943, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08670390313787028, \"functional effect\": -0.2029, \"times_seen\": 5.0}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 732, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.014296918375040133, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08656846736191677, \"functional effect\": -0.4477, \"times_seen\": 3.0}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02291110035480895, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.08605311613593031, \"functional effect\": -0.0938, \"times_seen\": 9.0}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.006996423369256541, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.08785564333144183, \"functional effect\": -1.4082, \"times_seen\": 4.0}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.007507439292451989, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.08697682808447496, \"functional effect\": -1.4028, \"times_seen\": 4.0}, {\"site\": 733, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.03222344295143376, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.0854994472552737, \"functional effect\": -1.017, \"times_seen\": 20.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.018212401979251776, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08633383852176776, \"functional effect\": -1.6831, \"times_seen\": 5.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0007662361285467001, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08738419099957269, \"functional effect\": -1.036, \"times_seen\": 1.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02651535840311552, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08583839956759227, \"functional effect\": -2.4426, \"times_seen\": 5.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.1080045281526736, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.0942271667028246, \"functional effect\": -1.5423, \"times_seen\": 4.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.018515809516808753, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08631568389976499, \"functional effect\": -1.4984, \"times_seen\": 5.0}, {\"site\": 734, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004350983840781651, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08716733198466825, \"functional effect\": -0.4777, \"times_seen\": 7.0}, {\"site\": 735, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 735, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.005125331210684877, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": 0.08774177349259224, \"functional effect\": -2.5456, \"times_seen\": 4.0}, {\"site\": 735, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.020898370210278953, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": 0.0861732541904705, \"functional effect\": -2.4725, \"times_seen\": 4.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01670767286539166, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08642393158211227, \"functional effect\": 0.0824, \"times_seen\": 6.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.23198850447561406, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.07444371391371908, \"functional effect\": -0.1671, \"times_seen\": 39.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.006854013184221184, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08701623059229004, \"functional effect\": -0.4855, \"times_seen\": 1.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.013024818116641372, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08822352189906577, \"functional effect\": -0.0817, \"times_seen\": 3.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0063112045056748405, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08704897628737276, \"functional effect\": -0.0087, \"times_seen\": 5.0}, {\"site\": 736, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0019080120920821554, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08754632071599966, \"functional effect\": -0.2664, \"times_seen\": 3.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.051669122435018935, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.09061862865789687, \"functional effect\": -0.4403, \"times_seen\": 25.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.003951229816590909, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08719148838559664, \"functional effect\": -0.0781, \"times_seen\": 4.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.036764132962643206, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08523077219223665, \"functional effect\": -0.9326, \"times_seen\": 6.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.194170750287437, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.03821046423801356, \"functional effect\": -0.3955, \"times_seen\": 2.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0003281668639843318, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08741072893006537, \"functional effect\": -0.0225, \"times_seen\": 6.0}, {\"site\": 737, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.028107490796209143, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08574372209989656, \"functional effect\": -0.2248, \"times_seen\": 8.0}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.011397922289206145, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.08674259561144022, \"functional effect\": -2.7764, \"times_seen\": 2.0}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0034940933955779274, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.08721912050416909, \"functional effect\": -2.4574, \"times_seen\": 1.0}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.014198266129287802, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.08829530964865388, \"functional effect\": -2.8876, \"times_seen\": 4.0}, {\"site\": 738, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.2046987827927327, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.03793263923403439, \"functional effect\": -0.1766, \"times_seen\": 6.0}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0375378760285877, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.08518507366546497, \"functional effect\": 0.1886, \"times_seen\": 6.0}, {\"site\": 739, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02981609859813004, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.08564223448815626, \"functional effect\": -2.1587, \"times_seen\": 1.0}, {\"site\": 740, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 740, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02102592774903159, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": 0.08616563542006071, \"functional effect\": -2.6612, \"times_seen\": 4.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.11395103454349399, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08079060317179626, \"functional effect\": -1.9342, \"times_seen\": 3.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.02636118514732322, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08904284700110175, \"functional effect\": -0.6324, \"times_seen\": 12.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.04385444566837351, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08481292209045514, \"functional effect\": -0.8634, \"times_seen\": 10.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03611998756628084, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08526883516889702, \"functional effect\": -1.8853, \"times_seen\": 8.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005520707548120553, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08709668616679826, \"functional effect\": -0.4687, \"times_seen\": 1.0}, {\"site\": 741, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.011805266646214391, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08814897553975573, \"functional effect\": -2.1101, \"times_seen\": 2.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.014272924921258746, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08656990709362286, \"functional effect\": -0.381, \"times_seen\": 4.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.03748249271247298, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08518834388008861, \"functional effect\": -1.2556, \"times_seen\": 9.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.01733283320887027, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08638648977437761, \"functional effect\": -0.5194, \"times_seen\": 11.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0041505637230253856, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08717944216733313, \"functional effect\": -2.9882, \"times_seen\": 1.0}, {\"site\": 742, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01573741592170526, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08838955841381235, \"functional effect\": -0.4782, \"times_seen\": 4.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00817766570758846, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08693643103076591, \"functional effect\": 0.0849, \"times_seen\": 2.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.03233592962332558, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08941237166772824, \"functional effect\": -2.1692, \"times_seen\": 3.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.047103570539806884, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08462212799086301, \"functional effect\": -0.953, \"times_seen\": 10.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.26227899896449314, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.10486181631769292, \"functional effect\": -0.334, \"times_seen\": 31.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004099633073463818, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08718251986834849, \"functional effect\": -2.1849, \"times_seen\": 1.0}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 743, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.003887959442145876, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08719531231160452, \"functional effect\": -0.7858, \"times_seen\": 1.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.017264408676098505, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08639058703347152, \"functional effect\": 0.3931, \"times_seen\": 11.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.1336432779812775, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.1918333721029627, \"functional effect\": -0.2878, \"times_seen\": 22.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0028837965196854645, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08725602422641951, \"functional effect\": 0.1667, \"times_seen\": 2.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0012553826519291157, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08735456836505809, \"functional effect\": -0.1635, \"times_seen\": 3.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.015221485153060734, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08835795454859399, \"functional effect\": -0.0825, \"times_seen\": 4.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.019561855538683018, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08862418109653589, \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 744, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.014731182395052689, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08654241340585125, \"functional effect\": -0.047, \"times_seen\": 4.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0725718451198003, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.09194112895250435, \"functional effect\": -0.1863, \"times_seen\": 8.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.8092123969066967, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.30640138915471343, \"functional effect\": -0.4162, \"times_seen\": 12.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.1046906540882195, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.09401097506010898, \"functional effect\": -0.5398, \"times_seen\": 13.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.007171657609367652, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.08786631520005007, \"functional effect\": -0.8477, \"times_seen\": 5.0}, {\"site\": 745, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.02433197667220481, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.0889176927011179, \"functional effect\": -0.5605, \"times_seen\": 11.0}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.002716954788612931, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.08726611560923533, \"functional effect\": -2.2959, \"times_seen\": 1.0}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.000617123526937637, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.08739322323236506, \"functional effect\": -3.1098, \"times_seen\": 1.0}, {\"site\": 746, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0189070287468871, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.08858396447550233, \"functional effect\": -2.3491, \"times_seen\": 5.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.013707411655403607, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08660384775732399, \"functional effect\": -1.0003, \"times_seen\": 13.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.06884951177153568, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.09170421512459408, \"functional effect\": 0.2269, \"times_seen\": 79.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.08348179921558924, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08251501905692805, \"functional effect\": -0.3044, \"times_seen\": 16.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.03655053957744749, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08524339168306876, \"functional effect\": -0.0421, \"times_seen\": 31.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.038810600833545233, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08510995775723301, \"functional effect\": -0.1217, \"times_seen\": 13.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.008114380737467236, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08694024465038462, \"functional effect\": 0.0836, \"times_seen\": 20.0}, {\"site\": 747, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02981788175981128, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08564212863497724, \"functional effect\": -0.0658, \"times_seen\": 14.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.3871164791496507, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.0668543788238943, \"functional effect\": 0.0264, \"times_seen\": 44.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.03200416829754772, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08939181281386252, \"functional effect\": -0.0541, \"times_seen\": 2.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03386180904993791, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08950698949721977, \"functional effect\": -0.2394, \"times_seen\": 5.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.03791109694417094, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08975856635443719, \"functional effect\": 0.2424, \"times_seen\": 9.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008905821240987304, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08689256363742967, \"functional effect\": 0.0683, \"times_seen\": 7.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.01611959875094454, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.0884129767006909, \"functional effect\": 0.0901, \"times_seen\": 9.0}, {\"site\": 748, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03820874744192775, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08514547073908002, \"functional effect\": 0.0153, \"times_seen\": 5.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.020073191929206407, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08622255680504644, \"functional effect\": -2.0375, \"times_seen\": 6.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.012251675135559012, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08817625541426995, \"functional effect\": -1.0664, \"times_seen\": 3.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.004922504893788995, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.0877294388762462, \"functional effect\": -0.0729, \"times_seen\": 12.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.7172983790994198, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.0531783921160036, \"functional effect\": -2.6643, \"times_seen\": 10.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013790928255335923, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08659883446667542, \"functional effect\": -0.3644, \"times_seen\": 2.0}, {\"site\": 749, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.015600831434666828, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08649026181074534, \"functional effect\": -0.776, \"times_seen\": 6.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.026297918083901233, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08903894225632406, \"functional effect\": -0.7661, \"times_seen\": 6.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.024330521348905648, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08891760300515239, \"functional effect\": -0.673, \"times_seen\": 2.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.03251581293937415, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08942352079918431, \"functional effect\": -2.7073, \"times_seen\": 2.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012698562522129388, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08666442935603766, \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 750, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0265638552836648, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08583551411742829, \"functional effect\": -0.3226, \"times_seen\": 12.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0050197510741994186, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.0871269345725142, \"functional effect\": -0.4671, \"times_seen\": 1.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.04079099962647717, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08993792103769564, \"functional effect\": 0.0366, \"times_seen\": 76.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.011059332356637924, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.0881034105756545, \"functional effect\": -2.891, \"times_seen\": 4.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0858687233861953, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08237861167635242, \"functional effect\": -0.0719, \"times_seen\": 24.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.020009089603917327, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08865165876563691, \"functional effect\": 0.1158, \"times_seen\": 12.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01277066780310587, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.0882079814970685, \"functional effect\": 0.0848, \"times_seen\": 5.0}, {\"site\": 751, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03012525541734572, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08562388407911195, \"functional effect\": 0.1702, \"times_seen\": 8.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.004708299116279675, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.08714574574388007, \"functional effect\": -2.2523, \"times_seen\": 1.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01346379468253436, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.086618473127257, \"functional effect\": -0.2403, \"times_seen\": 2.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.009883932509352652, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.0880316597490966, \"functional effect\": -1.4802, \"times_seen\": 3.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.028812553376778367, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.0891942735663714, \"functional effect\": -1.0858, \"times_seen\": 5.0}, {\"site\": 752, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.011616227908718212, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08672947089491971, \"functional effect\": -1.943, \"times_seen\": 2.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.014718759912884209, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08654315859189918, \"functional effect\": -2.4891, \"times_seen\": 6.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00563726122492947, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08708965000969479, \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.003263438955921554, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.0872330659916411, \"functional effect\": -2.9344, \"times_seen\": 1.0}, {\"site\": 753, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.04953872630821407, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08447941297366006, \"functional effect\": -1.7854, \"times_seen\": 7.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.010800513459971468, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.086778522485655, \"functional effect\": -2.8243, \"times_seen\": 1.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.5571354085499911, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.059422245645446535, \"functional effect\": -1.0894, \"times_seen\": 58.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.004097123023129647, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08718267155161993, \"functional effect\": -1.9744, \"times_seen\": 7.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01015502322239962, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08804820295956091, \"functional effect\": -1.7512, \"times_seen\": 5.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003964168690856207, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08719070640838433, \"functional effect\": -0.6318, \"times_seen\": 4.0}, {\"site\": 754, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.03138484605050613, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08935344680060436, \"functional effect\": -2.4308, \"times_seen\": 7.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.024293910715909337, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08597067450582077, \"functional effect\": -0.2737, \"times_seen\": 11.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.07966745624158286, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.09239443710807123, \"functional effect\": 0.0587, \"times_seen\": 5.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.01736351112111653, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08848924051127863, \"functional effect\": 0.3216, \"times_seen\": 5.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.012880598199171464, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08665349494344271, \"functional effect\": -0.1119, \"times_seen\": 7.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.04617212688813209, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08467678000779794, \"functional effect\": -0.4627, \"times_seen\": 3.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01155868622387904, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08673293015641591, \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 1.5350130433835665, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.2533660960706558, \"functional effect\": 0.1522, \"times_seen\": 15.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.02055614868509691, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08619369776282641, \"functional effect\": 0.0004, \"times_seen\": 9.0}, {\"site\": 755, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.00096968349893184, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08748939911777619, \"functional effect\": -0.2785, \"times_seen\": 1.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.004946720562694151, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.0871313451273914, \"functional effect\": -1.9521, \"times_seen\": 1.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.022950887596288192, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08883261270176684, \"functional effect\": -1.2458, \"times_seen\": 7.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.011147221046734952, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08675767043006906, \"functional effect\": -1.2885, \"times_seen\": 9.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.1012620432639278, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.09378782024877184, \"functional effect\": -1.2136, \"times_seen\": 15.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00902352857947447, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08688547449184983, \"functional effect\": -1.5576, \"times_seen\": 2.0}, {\"site\": 756, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009855282793808491, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08683539701223916, \"functional effect\": -0.2353, \"times_seen\": 2.0}, {\"site\": 757, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 757, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.006575973615110877, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": 0.0870330021802427, \"functional effect\": -1.2855, \"times_seen\": 1.0}, {\"site\": 757, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.049940094650821505, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": 0.084455913450332, \"functional effect\": -1.6236, \"times_seen\": 5.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -1.119265626922159, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.04024676733988561, \"functional effect\": 0.1197, \"times_seen\": 47.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.017741599593996835, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08636201690237884, \"functional effect\": -1.0763, \"times_seen\": 5.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.011028060357527084, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08810150085818917, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.20419716794671522, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.0758916608742031, \"functional effect\": -0.1772, \"times_seen\": 71.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06962779196404476, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08331121650363675, \"functional effect\": -0.2376, \"times_seen\": 9.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04327612074434568, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.09009297753425358, \"functional effect\": 0.1582, \"times_seen\": 6.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.026382968060193395, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08584627697499363, \"functional effect\": -0.1127, \"times_seen\": 10.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.006557556493694141, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08703411323112605, \"functional effect\": -0.0003, \"times_seen\": 5.0}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 758, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.007213519036399346, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08786886477747444, \"functional effect\": -0.115, \"times_seen\": 15.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.011166521833332999, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08675650976892142, \"functional effect\": -0.3831, \"times_seen\": 7.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.028977297112363562, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08569204246487666, \"functional effect\": -1.9731, \"times_seen\": 7.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.015008448969693295, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08652578271661673, \"functional effect\": -1.1412, \"times_seen\": 3.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04992104449133301, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.09050889479833661, \"functional effect\": 0.3165, \"times_seen\": 10.0}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 759, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.013110327945463542, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08663969764049441, \"functional effect\": -0.0864, \"times_seen\": 5.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.024876646936961545, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08895126872738013, \"functional effect\": -1.6237, \"times_seen\": 8.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.001903315325314081, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08754603570498289, \"functional effect\": -0.6558, \"times_seen\": 1.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0018634468339931212, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08731775809652022, \"functional effect\": -0.0134, \"times_seen\": 9.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.005181951317225348, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08711713956028384, \"functional effect\": 0.16, \"times_seen\": 7.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004502243046034571, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08715819341426506, \"functional effect\": -0.4704, \"times_seen\": 1.0}, {\"site\": 760, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.023880500564056117, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.0888898712059225, \"functional effect\": -1.5481, \"times_seen\": 1.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0182074712292906, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08633413358849103, \"functional effect\": -2.5877, \"times_seen\": 4.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.6886670161275417, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.14092010523928367, \"functional effect\": -0.226, \"times_seen\": 37.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04668941141559568, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08464642422564381, \"functional effect\": -0.6222, \"times_seen\": 14.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03369236007669296, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08541243809308266, \"functional effect\": -1.3145, \"times_seen\": 12.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.011054481286942534, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08810311432796913, \"functional effect\": -1.8716, \"times_seen\": 17.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.022857619776799683, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0860563061764878, \"functional effect\": -1.4497, \"times_seen\": 5.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07848845873004327, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08280110823859305, \"functional effect\": -0.2276, \"times_seen\": 38.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.032978814182025015, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08545469287801545, \"functional effect\": -0.085, \"times_seen\": 12.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02164975745262871, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0861283849537666, \"functional effect\": -1.4162, \"times_seen\": 5.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.28220302515238177, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.07189719622386781, \"functional effect\": -0.7349, \"times_seen\": 32.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03184743142804946, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08552173399387954, \"functional effect\": -0.265, \"times_seen\": 20.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.010674949141484518, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08678607554428266, \"functional effect\": -0.6305, \"times_seen\": 35.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0025368944972038055, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08758449118215222, \"functional effect\": -2.9308, \"times_seen\": 6.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06554770843211424, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08354716230315808, \"functional effect\": 0.3452, \"times_seen\": 23.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.07913819059182096, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0827638263431391, \"functional effect\": 0.1124, \"times_seen\": 69.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.67087464512654, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.02745871078388386, \"functional effect\": -0.3048, \"times_seen\": 47.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08959434757440835, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08216615111115076, \"functional effect\": -0.0973, \"times_seen\": 35.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003847785924858666, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08719774040004971, \"functional effect\": -0.3854, \"times_seen\": 22.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.019477029997987633, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08625819373903626, \"functional effect\": -0.8069, \"times_seen\": 11.0}, {\"site\": 761, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008356512562220263, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0879385075890876, \"functional effect\": -0.3796, \"times_seen\": 12.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0018981948247116139, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08731565503244698, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0171278858122436, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08639876259939824, \"functional effect\": -1.5482, \"times_seen\": 4.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.8488352662895651, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.15746658409656986, \"functional effect\": -0.2881, \"times_seen\": 27.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.8140000923773646, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.15370994750358674, \"functional effect\": -0.9356, \"times_seen\": 4.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004226237823683734, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08717486943874195, \"functional effect\": -0.0548, \"times_seen\": 9.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.016646220075123976, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08844525563450245, \"functional effect\": -0.5001, \"times_seen\": 12.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.6394617069603058, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.056126295064683494, \"functional effect\": -0.2185, \"times_seen\": 1.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01354966500396894, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08661331768236617, \"functional effect\": -0.495, \"times_seen\": 19.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.05471670736499785, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.09081025603359588, \"functional effect\": -0.7384, \"times_seen\": 6.0}, {\"site\": 762, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0029657302994527354, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08725106890830735, \"functional effect\": -0.9641, \"times_seen\": 1.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004514302804039787, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08715746484565023, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.011360313618585081, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08812179300661373, \"functional effect\": -0.9905, \"times_seen\": 2.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.019146501151881885, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08859866971473615, \"functional effect\": -1.6376, \"times_seen\": 8.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.017939721840466563, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08635015780429436, \"functional effect\": -0.6086, \"times_seen\": 3.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.005497335912291761, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08709809714310418, \"functional effect\": -1.5951, \"times_seen\": 1.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.011965908234517129, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08815879132163157, \"functional effect\": -0.3293, \"times_seen\": 1.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0067491711153174596, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08702255437720664, \"functional effect\": 0.2056, \"times_seen\": 2.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.14621791251654487, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.07900372204830983, \"functional effect\": -0.0657, \"times_seen\": 18.0}, {\"site\": 763, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.018942052754679962, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08629018575839127, \"functional effect\": -0.633, \"times_seen\": 11.0}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.009510037221076715, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.0880088480272256, \"functional effect\": -0.3954, \"times_seen\": 6.0}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004261878524797153, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.08717271587544492, \"functional effect\": -1.116, \"times_seen\": 1.0}, {\"site\": 764, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.009036152978812476, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.0868847141980272, \"functional effect\": -2.3797, \"times_seen\": 2.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01192298973267399, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08815616873899168, \"functional effect\": -0.8115, \"times_seen\": 11.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -1.3586989732598143, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.03409214947657056, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.002255658486428358, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08729402308223515, \"functional effect\": -0.697, \"times_seen\": 11.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.7208292069578298, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.053048403334298666, \"functional effect\": -0.4963, \"times_seen\": 43.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.04382818921413915, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08481446566467461, \"functional effect\": -1.1789, \"times_seen\": 8.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.023911185685094295, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08599348424235713, \"functional effect\": 0.1124, \"times_seen\": 70.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03469408107521174, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08535315339773811, \"functional effect\": -0.4113, \"times_seen\": 7.0}, {\"site\": 765, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.08314449796678204, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09261738565151677, \"functional effect\": -0.3442, \"times_seen\": 112.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -1.2245550564629473, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.03741413652193375, \"functional effect\": -0.7485, \"times_seen\": 108.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.2139612885577548, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.1014080182641106, \"functional effect\": -0.2311, \"times_seen\": 125.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.026136888851626322, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08586092094688993, \"functional effect\": -0.1186, \"times_seen\": 55.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.2815826598221487, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.10627432539037382, \"functional effect\": -0.4384, \"times_seen\": 57.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.09564665521403669, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09342348033524307, \"functional effect\": -0.2743, \"times_seen\": 49.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0033379547495594165, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08722856048417596, \"functional effect\": -0.8515, \"times_seen\": 44.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0238260678308705, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.0888865174636361, \"functional effect\": -0.3583, \"times_seen\": 35.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.2954906694410959, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.10730379574767583, \"functional effect\": -0.5519, \"times_seen\": 83.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.04780050522261953, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08458125874856558, \"functional effect\": -0.1667, \"times_seen\": 23.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.05497397628934545, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09082645123731302, \"functional effect\": -0.2105, \"times_seen\": 79.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.004740569405252615, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08771837618350846, \"functional effect\": -2.7401, \"times_seen\": 12.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05482256170774046, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08417057508495975, \"functional effect\": 0.0564, \"times_seen\": 20.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.11492876341892282, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09468049833852961, \"functional effect\": -0.2939, \"times_seen\": 212.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06683262048965803, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.0834727855552712, \"functional effect\": -0.2042, \"times_seen\": 153.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.012622510446223511, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.0866689980162877, \"functional effect\": -0.6609, \"times_seen\": 65.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.014480579678263156, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08831258939287677, \"functional effect\": -0.8462, \"times_seen\": 148.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.023266588426055317, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08603191478232189, \"functional effect\": -0.3517, \"times_seen\": 39.0}, {\"site\": 766, \"wildtype\": \"G\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.2957861307771206, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.1073257736214805, \"functional effect\": -0.1698, \"times_seen\": 58.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.013540490933405517, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08661386845657143, \"functional effect\": -0.5587, \"times_seen\": 3.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.014024281217756186, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08658482841565879, \"functional effect\": -0.6704, \"times_seen\": 11.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0055460600626930255, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08709515562809042, \"functional effect\": -0.4593, \"times_seen\": 1.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006046710070796228, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08706493675011755, \"functional effect\": -2.8362, \"times_seen\": 1.0}, {\"site\": 767, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.07053014417690388, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08325912472164493, \"functional effect\": -0.2712, \"times_seen\": 18.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.02324618567889116, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08885079726905393, \"functional effect\": -2.7602, \"times_seen\": 2.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.04123961535725438, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.0899658921881128, \"functional effect\": -1.0503, \"times_seen\": 18.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004411166312780537, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08716369584816601, \"functional effect\": -2.9103, \"times_seen\": 5.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.00983670196143478, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08683651539436461, \"functional effect\": -2.5854, \"times_seen\": 3.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.007150168338352425, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08699836981119563, \"functional effect\": -2.4737, \"times_seen\": 1.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.11984418168861516, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.0950036352202655, \"functional effect\": -0.4717, \"times_seen\": 47.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0070374911724119015, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08700516481103247, \"functional effect\": -3.0029, \"times_seen\": 1.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011171850032936382, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08675618935806935, \"functional effect\": -2.686, \"times_seen\": 2.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.015322198311142145, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.086506967613732, \"functional effect\": -2.7146, \"times_seen\": 3.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.006859944187300019, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08701587286424906, \"functional effect\": -2.8167, \"times_seen\": 1.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -2.6004853808753476, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.014415822525627831, \"functional effect\": -0.1069, \"times_seen\": 19.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.014699139006108272, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08832596921448589, \"functional effect\": -2.9758, \"times_seen\": 3.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008292621989747085, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08692950407083458, \"functional effect\": -2.2876, \"times_seen\": 2.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.003223173064324366, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.087235500716997, \"functional effect\": -2.9508, \"times_seen\": 4.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.2370836742084842, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.07418126457987036, \"functional effect\": -0.4086, \"times_seen\": 66.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08158846603166094, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08262337943665932, \"functional effect\": -2.2719, \"times_seen\": 15.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.06697257986114462, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.09158498642658523, \"functional effect\": -2.6338, \"times_seen\": 10.0}, {\"site\": 768, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.019908277235976733, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08864546419842721, \"functional effect\": -2.4901, \"times_seen\": 3.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0003240838302660081, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08745025675616025, \"functional effect\": -1.0373, \"times_seen\": 5.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0171578056401315, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08847662424545863, \"functional effect\": -0.8523, \"times_seen\": 7.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005953419848769493, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08707056688653964, \"functional effect\": -0.8312, \"times_seen\": 2.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.030297797143115143, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08928614568736158, \"functional effect\": -0.7854, \"times_seen\": 5.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.001145730529669474, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08750007579460578, \"functional effect\": -1.3317, \"times_seen\": 5.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.026344428008671445, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08904181275988973, \"functional effect\": -0.3216, \"times_seen\": 19.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03106806063275753, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08556794691263656, \"functional effect\": -0.6707, \"times_seen\": 9.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.09818794644022799, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08167817264317785, \"functional effect\": -0.6794, \"times_seen\": 21.0}, {\"site\": 769, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0025839861455721888, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.08727415902201471, \"functional effect\": -0.6339, \"times_seen\": 5.0}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.02949858919970752, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.08923669765198888, \"functional effect\": -1.584, \"times_seen\": 1.0}, {\"site\": 770, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.002236710409746679, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.08729516959252208, \"functional effect\": -2.1972, \"times_seen\": 3.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.009062675604321838, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.0868831169169042, \"functional effect\": -2.8012, \"times_seen\": 3.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0038687206414951244, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.08719647509678709, \"functional effect\": -3.2328, \"times_seen\": 1.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.08506079635218661, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.09274048891778859, \"functional effect\": -2.8752, \"times_seen\": 2.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0021776557200321074, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.08729874297048443, \"functional effect\": -0.3916, \"times_seen\": 1.0}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 771, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.015157708877444234, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.08651683130143534, \"functional effect\": -2.932, \"times_seen\": 2.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0048271660393763806, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.087138565903626, \"functional effect\": -1.7483, \"times_seen\": 2.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.004072703002720943, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.08718414727627191, \"functional effect\": -1.6581, \"times_seen\": 1.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.014531919710323, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.0865543673282724, \"functional effect\": -2.7155, \"times_seen\": 3.0}, {\"site\": 772, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.023156277473974588, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.08884526029377562, \"functional effect\": -2.5069, \"times_seen\": 1.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.000927609695394655, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08748684767203682, \"functional effect\": -0.0735, \"times_seen\": 5.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.006551886627527955, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.0878285765959682, \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.025797737197776924, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08588110767766963, \"functional effect\": -1.9023, \"times_seen\": 3.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.020048232561355656, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08622404851262656, \"functional effect\": 0.3042, \"times_seen\": 9.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.010078568801656088, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08804353704209573, \"functional effect\": 0.1008, \"times_seen\": 22.0}, {\"site\": 773, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010046993297376421, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08682385877914608, \"functional effect\": 0.2622, \"times_seen\": 2.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.020299130228211785, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08866948316132492, \"functional effect\": -1.6319, \"times_seen\": 2.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01739453113367728, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.0863827954709849, \"functional effect\": -1.7783, \"times_seen\": 4.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004761891206612522, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08714250858300959, \"functional effect\": -2.3639, \"times_seen\": 1.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.012882578072296914, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08821482408094598, \"functional effect\": -1.8787, \"times_seen\": 5.0}, {\"site\": 774, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0013666949876901303, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08734782871068875, \"functional effect\": -2.8274, \"times_seen\": 1.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.053512768131985675, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.09073450584298316, \"functional effect\": -0.946, \"times_seen\": 13.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03419442327461537, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08952762776742254, \"functional effect\": -2.3628, \"times_seen\": 2.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01928965589494471, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.0862693974937092, \"functional effect\": -0.4753, \"times_seen\": 40.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.013693501057898117, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08826442259961793, \"functional effect\": -1.1689, \"times_seen\": 12.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.02172653469166074, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08875725628453612, \"functional effect\": -2.5316, \"times_seen\": 2.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01900916837571814, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08859023624693697, \"functional effect\": -0.8224, \"times_seen\": 4.0}, {\"site\": 775, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.02188454944744298, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.0861143690950508, \"functional effect\": -1.8032, \"times_seen\": 1.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -1.928108540775432, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.02297444476085855, \"functional effect\": 0.3651, \"times_seen\": 14.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0010708482357959929, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.08736574255974419, \"functional effect\": -0.3563, \"times_seen\": 11.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0073805578564162784, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.08698447781628506, \"functional effect\": -0.2552, \"times_seen\": 27.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.216965227381127, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.037611486038818406, \"functional effect\": 0.0398, \"times_seen\": 17.0}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 776, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.01802230493553292, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.08852965756053464, \"functional effect\": -0.0258, \"times_seen\": 15.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0037876653638831644, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08720137421464863, \"functional effect\": -3.0345, \"times_seen\": 1.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.00044252317716465995, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08740380052714512, \"functional effect\": 0.0559, \"times_seen\": 3.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.07258371679385543, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08314069565409861, \"functional effect\": 0.2593, \"times_seen\": 26.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.013419178258237376, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08662115190981187, \"functional effect\": -0.1689, \"times_seen\": 14.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.005590055208697112, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08777004161211746, \"functional effect\": -0.0755, \"times_seen\": 21.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.1088236400933319, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08107824697271819, \"functional effect\": 0.0878, \"times_seen\": 10.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.018621061755728825, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08630938694348629, \"functional effect\": -0.192, \"times_seen\": 10.0}, {\"site\": 777, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.016171411004755738, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08645606205437398, \"functional effect\": -0.4499, \"times_seen\": 6.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.01162821857968554, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08672875006328339, \"functional effect\": -1.1213, \"times_seen\": 1.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02634526549434212, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08904186444875106, \"functional effect\": -1.5907, \"times_seen\": 1.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.039118304104375064, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08509180713008244, \"functional effect\": -2.2896, \"times_seen\": 9.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.00842240940256739, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08692168408973242, \"functional effect\": -2.2113, \"times_seen\": 2.0}, {\"site\": 778, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.020967744839587712, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.0887105864093426, \"functional effect\": -2.2009, \"times_seen\": 3.0}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005534326669922335, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.0870958639730948, \"functional effect\": -2.3996, \"times_seen\": 2.0}, {\"site\": 779, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.030675476911003897, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.08559123468524439, \"functional effect\": -0.2612, \"times_seen\": 8.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01898172033207409, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08628781320184403, \"functional effect\": -1.3972, \"times_seen\": 3.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0165233197095604, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08843772147727597, \"functional effect\": -1.0212, \"times_seen\": 2.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005996993162139882, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08706793715836043, \"functional effect\": -0.1269, \"times_seen\": 1.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.04584940693402541, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08469572368086821, \"functional effect\": -0.1099, \"times_seen\": 14.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.005679142139358937, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08708712186539844, \"functional effect\": -0.5215, \"times_seen\": 1.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02658105063067918, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08583449105807504, \"functional effect\": -0.5208, \"times_seen\": 6.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006019733493734736, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08706656476980858, \"functional effect\": -0.8397, \"times_seen\": 1.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06289041688181518, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.0837011891393388, \"functional effect\": -0.7879, \"times_seen\": 22.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.12139106208688756, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.0803750357437712, \"functional effect\": -1.0432, \"times_seen\": 39.0}, {\"site\": 780, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05702975062609295, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08404190040705004, \"functional effect\": -0.59, \"times_seen\": 47.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.019906478867247404, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08623252097391791, \"functional effect\": -2.5266, \"times_seen\": 1.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -2.581756911408627, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.014604182724543778, \"functional effect\": 0.1042, \"times_seen\": 16.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06731883111802957, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08344465867038742, \"functional effect\": -0.2481, \"times_seen\": 11.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.32302593758217896, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.10937146428124157, \"functional effect\": 0.0136, \"times_seen\": 49.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03351778241467834, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.0854227743079753, \"functional effect\": -1.9129, \"times_seen\": 5.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.09638929524474098, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08178006677580071, \"functional effect\": 0.0575, \"times_seen\": 60.0}, {\"site\": 781, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03131935292779914, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08555304376777557, \"functional effect\": -0.377, \"times_seen\": 5.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.025644719830792542, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08899863788462624, \"functional effect\": -0.4484, \"times_seen\": 14.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.004967323511818269, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.0871301008243324, \"functional effect\": -1.1697, \"times_seen\": 1.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.05126915469711827, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.084378145599155, \"functional effect\": -0.1905, \"times_seen\": 16.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.028558144524024255, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08571694257099775, \"functional effect\": -1.029, \"times_seen\": 8.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.011837540323642929, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08815094749040539, \"functional effect\": -1.0268, \"times_seen\": 8.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.030714365203870858, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08931193015721965, \"functional effect\": -0.767, \"times_seen\": 4.0}, {\"site\": 782, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01186718387678562, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08671438566568376, \"functional effect\": 0.0321, \"times_seen\": 3.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.030094263301546336, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.085625723479511, \"functional effect\": -0.2182, \"times_seen\": 9.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010040704165831704, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.0868242372706802, \"functional effect\": -0.0847, \"times_seen\": 2.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.022024978405488917, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08877561899076757, \"functional effect\": 0.0834, \"times_seen\": 8.0}, {\"site\": 783, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.010379978556395341, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.0880619331358221, \"functional effect\": -0.3067, \"times_seen\": 7.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.029336890226851698, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08567068630322107, \"functional effect\": -2.609, \"times_seen\": 4.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.1614123312232525, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.07817602363500074, \"functional effect\": -0.1617, \"times_seen\": 51.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.012797394216277565, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08820961559487049, \"functional effect\": -0.249, \"times_seen\": 36.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01069885381501646, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.0867846375580438, \"functional effect\": -0.255, \"times_seen\": 16.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.020979492943309253, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08871130879722372, \"functional effect\": -0.6562, \"times_seen\": 8.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -1.328043655449959, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.03482431272145619, \"functional effect\": -0.731, \"times_seen\": 1.0}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 784, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0273992912312568, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08578582287076027, \"functional effect\": -1.191, \"times_seen\": 9.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 1.8554040463830948, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.3163703696913798, \"functional effect\": -2.6049, \"times_seen\": 2.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.06906073251711183, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.09171764225240103, \"functional effect\": 0.3002, \"times_seen\": 18.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05143239386656669, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.08436859885587182, \"functional effect\": -0.317, \"times_seen\": 13.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.004075590869345413, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.08718397275849098, \"functional effect\": -0.9981, \"times_seen\": 2.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.004592020799312915, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.08770934463400942, \"functional effect\": -3.162, \"times_seen\": 1.0}, {\"site\": 785, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04191883788779259, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.09000825820869977, \"functional effect\": -1.9642, \"times_seen\": 2.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.008998105872640565, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.0868870055731564, \"functional effect\": -2.8941, \"times_seen\": 2.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.007630357610149914, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.0869694179321866, \"functional effect\": -2.9036, \"times_seen\": 2.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.043869453549989224, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08481203981413368, \"functional effect\": 0.0132, \"times_seen\": 13.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.03142939621063495, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08935620606137165, \"functional effect\": -2.782, \"times_seen\": 3.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02851129859396708, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08917565050639739, \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0064601772173133835, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.0870399880728406, \"functional effect\": -2.8037, \"times_seen\": 3.0}, {\"site\": 786, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.037300567809583775, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08972058977271834, \"functional effect\": -2.1323, \"times_seen\": 13.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.002545256166818858, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08758499881174836, \"functional effect\": -0.6658, \"times_seen\": 2.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0019240298588156291, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08754729271929107, \"functional effect\": -0.5911, \"times_seen\": 3.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02558902138891001, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08589353306280173, \"functional effect\": -1.1482, \"times_seen\": 18.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.04630748689197222, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.09028247837616508, \"functional effect\": -0.3125, \"times_seen\": 14.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.013658671001119286, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08826229171425824, \"functional effect\": 0.187, \"times_seen\": 16.0}, {\"site\": 787, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0585308482268693, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08395450183477862, \"functional effect\": 0.0374, \"times_seen\": 8.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.027029117848315225, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08580783701908129, \"functional effect\": 0.064, \"times_seen\": 7.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.015129185660990313, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08651854182419372, \"functional effect\": -0.09, \"times_seen\": 6.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01133145071804595, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08674659233235943, \"functional effect\": -0.0181, \"times_seen\": 25.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.03167933040218592, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08553169946017478, \"functional effect\": -0.5386, \"times_seen\": 23.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.015267097895090249, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.0865102716113178, \"functional effect\": -0.9177, \"times_seen\": 3.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.012253425184105162, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08669117341793263, \"functional effect\": 0.036, \"times_seen\": 5.0}, {\"site\": 788, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004253996240397196, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08717319215213268, \"functional effect\": -0.6043, \"times_seen\": 7.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0245448033131501, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08893081082326458, \"functional effect\": -0.4385, \"times_seen\": 36.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.029616728444587882, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08565407045126514, \"functional effect\": -0.2454, \"times_seen\": 4.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.2744058757342053, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.10574696934030359, \"functional effect\": -0.6375, \"times_seen\": 4.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.014543516152009685, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08655367160352737, \"functional effect\": -0.269, \"times_seen\": 11.0}, {\"site\": 789, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04209872383557919, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08491620001132921, \"functional effect\": -0.2892, \"times_seen\": 20.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08049865928142512, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08268581642571597, \"functional effect\": -0.053, \"times_seen\": 26.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.018909905136416556, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.0862921085866953, \"functional effect\": 0.3933, \"times_seen\": 16.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0014333408551569597, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08734379373642699, \"functional effect\": 0.2878, \"times_seen\": 9.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.007819104185131778, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08790575632263209, \"functional effect\": 0.3498, \"times_seen\": 1.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.43524350114907184, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.06466096484594562, \"functional effect\": 0.3254, \"times_seen\": 26.0}, {\"site\": 790, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.025219315566038816, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08591554700725158, \"functional effect\": 0.1526, \"times_seen\": 8.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.015597192728116117, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08838096778065933, \"functional effect\": 0.31, \"times_seen\": 12.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.00810032074687982, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08694109194308561, \"functional effect\": -0.5619, \"times_seen\": 2.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.021330230710520908, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08873287828208033, \"functional effect\": 0.2922, \"times_seen\": 3.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.016047757758159416, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08840857416398103, \"functional effect\": 0.3158, \"times_seen\": 9.0}, {\"site\": 791, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.005812410616154418, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08778357021438775, \"functional effect\": 0.0945, \"times_seen\": 4.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.009996879579766653, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08682687476089408, \"functional effect\": -0.9126, \"times_seen\": 14.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0029069232993606943, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08760695812074319, \"functional effect\": -0.2489, \"times_seen\": 2.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0025640432059076367, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08727536545529978, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.025455695004186814, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08898697786668966, \"functional effect\": 0.1416, \"times_seen\": 34.0}, {\"site\": 792, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0033570637034991435, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08763429694374486, \"functional effect\": 0.4099, \"times_seen\": 23.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.010719415751055136, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08678340067332484, \"functional effect\": -3.0468, \"times_seen\": 2.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.07891249909133306, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08277677471597938, \"functional effect\": -0.2063, \"times_seen\": 20.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.04625152895163969, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.0902789766495912, \"functional effect\": -0.1096, \"times_seen\": 18.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -6.47827064098727, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.000980640322867004, \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0348827164814758, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08534199402326097, \"functional effect\": 0.3958, \"times_seen\": 14.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02364288174805475, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.0860094782918927, \"functional effect\": -1.3189, \"times_seen\": 15.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.17324252078143862, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.077537596500825, \"functional effect\": 0.1069, \"times_seen\": 27.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.126951780062377, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08006583480281072, \"functional effect\": 0.3463, \"times_seen\": 26.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.04688527470107143, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08463493323071744, \"functional effect\": 0.1034, \"times_seen\": 16.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0185127353130905, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.0863158678279491, \"functional effect\": -0.3197, \"times_seen\": 3.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07724339222676509, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08287259762581516, \"functional effect\": 0.3055, \"times_seen\": 21.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.001463961034323025, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08751937874066734, \"functional effect\": 0.0388, \"times_seen\": 3.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.12444902074361074, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08020485200428676, \"functional effect\": 0.4141, \"times_seen\": 44.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01440405337974027, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.0865620389979596, \"functional effect\": -0.2016, \"times_seen\": 4.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0008650364708559895, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08737820685731292, \"functional effect\": -1.0075, \"times_seen\": 13.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.7681440147597052, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.025668420475008415, \"functional effect\": 0.4444, \"times_seen\": 52.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.09177510385954434, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08204204380683333, \"functional effect\": 0.0623, \"times_seen\": 20.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.003811039614262986, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08766187735314107, \"functional effect\": -0.0814, \"times_seen\": 26.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0029381203932524456, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08725273871156558, \"functional effect\": -1.3168, \"times_seen\": 7.0}, {\"site\": 793, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01517647675648355, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08651570581973808, \"functional effect\": -1.1026, \"times_seen\": 6.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005356847650419023, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.0871065790853929, \"functional effect\": -0.7217, \"times_seen\": 2.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02840634251116787, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08572596227969732, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.1468742033862509, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.09680038191475458, \"functional effect\": -1.0526, \"times_seen\": 4.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.058308726915494075, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.0910366369522423, \"functional effect\": -1.2891, \"times_seen\": 2.0}, {\"site\": 794, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00667088665204406, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08702727658017047, \"functional effect\": -0.3219, \"times_seen\": 2.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0008767484623431099, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08737749751221091, \"functional effect\": 0.0924, \"times_seen\": 3.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.015562989536811343, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08649253048048175, \"functional effect\": -1.6839, \"times_seen\": 2.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.014693262083437913, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08654468814744286, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0048537870763883115, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08713695801178441, \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01684390107112256, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08641577128422681, \"functional effect\": -0.3295, \"times_seen\": 4.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.06654739857753651, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.09155799909839088, \"functional effect\": -0.3617, \"times_seen\": 10.0}, {\"site\": 795, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0276468908040296, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08577110131844765, \"functional effect\": -0.7709, \"times_seen\": 3.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.030171771035321017, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08562112342383736, \"functional effect\": -2.0614, \"times_seen\": 6.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.008499952256955701, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08691701229550856, \"functional effect\": -2.0504, \"times_seen\": 9.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.006371295456469358, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08704535060996584, \"functional effect\": -2.6231, \"times_seen\": 2.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.008341155539133, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08692657973388553, \"functional effect\": -3.0068, \"times_seen\": 2.0}, {\"site\": 796, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.003225221736334287, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08723537683994978, \"functional effect\": -1.0263, \"times_seen\": 1.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04761906414239969, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.09036459294857026, \"functional effect\": -2.5187, \"times_seen\": 2.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.01122988712149707, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.08811382673727813, \"functional effect\": -2.5735, \"times_seen\": 4.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0027762587444617472, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.08726252848974397, \"functional effect\": -2.3392, \"times_seen\": 1.0}, {\"site\": 797, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003984556709341593, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.08718947424696219, \"functional effect\": -2.9684, \"times_seen\": 1.0}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.030152467995409944, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.08927715194609989, \"functional effect\": 0.1322, \"times_seen\": 18.0}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.012254325393194964, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.08669111932461716, \"functional effect\": -2.2033, \"times_seen\": 1.0}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.00926735244634129, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.08687079158126072, \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 798, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 799, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 799, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01462090352909673, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": 0.08654902891620364, \"functional effect\": -2.1336, \"times_seen\": 3.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0017459452310360326, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08753648664844599, \"functional effect\": -0.9067, \"times_seen\": 2.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.014722190128004993, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08832738048221116, \"functional effect\": -2.2039, \"times_seen\": 4.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.016102678014782514, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08841193974982002, \"functional effect\": -0.764, \"times_seen\": 3.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.016356265144219687, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.088427481565601, \"functional effect\": -0.5422, \"times_seen\": 7.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.003166724160810817, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08762273582289953, \"functional effect\": -1.4122, \"times_seen\": 15.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0336822366752463, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.085413037434876, \"functional effect\": -0.3901, \"times_seen\": 8.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01382520930297193, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08659677674594105, \"functional effect\": -0.2646, \"times_seen\": 3.0}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 800, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010499821848656637, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08679661105770979, \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.029445343607708913, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08923340425111084, \"functional effect\": -0.4395, \"times_seen\": 11.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.005359063901953441, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.0871064452733704, \"functional effect\": -0.1603, \"times_seen\": 17.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009545100443700933, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08685406880529374, \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.00869135003924728, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08795891975134384, \"functional effect\": 0.3861, \"times_seen\": 5.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005953915123998575, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08707053699533855, \"functional effect\": -0.0333, \"times_seen\": 7.0}, {\"site\": 801, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.002325868374029111, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.0875716809461561, \"functional effect\": 0.1817, \"times_seen\": 3.0}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.008993330839236523, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.08688729315232513, \"functional effect\": 0.0932, \"times_seen\": 4.0}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0005808813081673504, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.08739541868186027, \"functional effect\": -0.5141, \"times_seen\": 19.0}, {\"site\": 802, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0013718884142238175, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.08751379344290691, \"functional effect\": -0.3151, \"times_seen\": 4.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009744153905545812, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08684208608548623, \"functional effect\": -0.2975, \"times_seen\": 2.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009739271390453318, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08684237998579188, \"functional effect\": -1.7201, \"times_seen\": 2.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.003934447891303647, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08719250263289963, \"functional effect\": 0.0086, \"times_seen\": 3.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.007932109291614755, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08791264217732447, \"functional effect\": -1.5347, \"times_seen\": 5.0}, {\"site\": 803, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.014120416731442263, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08829054526599496, \"functional effect\": -0.0491, \"times_seen\": 3.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.07054665765778342, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08325817172045169, \"functional effect\": -0.766, \"times_seen\": 11.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05491391745909191, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08416524532194274, \"functional effect\": -1.3191, \"times_seen\": 21.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0025645065736184533, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08758616749817044, \"functional effect\": -0.3064, \"times_seen\": 9.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.2687593554916186, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.03628514865642148, \"functional effect\": -0.0774, \"times_seen\": 61.0}, {\"site\": 804, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.012903094360314386, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.0866521437529747, \"functional effect\": -0.4701, \"times_seen\": 3.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01266396778832948, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08820145798057441, \"functional effect\": -1.2046, \"times_seen\": 5.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.00905889300186245, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08688334471606705, \"functional effect\": -0.2332, \"times_seen\": 11.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0903611932026859, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08212248837632816, \"functional effect\": -1.829, \"times_seen\": 17.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.003889530300588021, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08719521737025239, \"functional effect\": -0.8279, \"times_seen\": 30.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04648478735051685, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.09029357435140693, \"functional effect\": -1.4157, \"times_seen\": 4.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.06916291509023141, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08333806604377789, \"functional effect\": -0.4902, \"times_seen\": 37.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.010816840598868812, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08808860318053317, \"functional effect\": -1.0512, \"times_seen\": 3.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.012313936324604879, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08668753739533921, \"functional effect\": -0.6862, \"times_seen\": 3.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.015326822583031504, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08650669033330466, \"functional effect\": -0.0955, \"times_seen\": 5.0}, {\"site\": 805, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012766511092174044, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08666034769968678, \"functional effect\": -2.7158, \"times_seen\": 3.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.02963788308294417, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.0892453139748303, \"functional effect\": -0.4214, \"times_seen\": 3.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.007595310828286602, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08789212128682668, \"functional effect\": -0.1099, \"times_seen\": 24.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.044265572749333924, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08478875626174609, \"functional effect\": -0.1306, \"times_seen\": 14.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.021864231551585372, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08876572805327324, \"functional effect\": -0.3906, \"times_seen\": 2.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.004641618216584212, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08714977368523875, \"functional effect\": -0.0518, \"times_seen\": 11.0}, {\"site\": 806, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.11164862072063393, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08091964077551231, \"functional effect\": -0.1149, \"times_seen\": 28.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.04461969190717563, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.09017691953545932, \"functional effect\": -0.0312, \"times_seen\": 19.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03798858918557772, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08515846510602168, \"functional effect\": -0.0043, \"times_seen\": 8.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.09382736626547446, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.09330574430645044, \"functional effect\": -0.3514, \"times_seen\": 25.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04161530407795626, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08494465858781212, \"functional effect\": -0.1477, \"times_seen\": 15.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.045639723622877604, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08470803437018222, \"functional effect\": -0.4062, \"times_seen\": 25.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.9372136981218135, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.045659809423045664, \"functional effect\": 0.1263, \"times_seen\": 17.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 1.2826100300757626, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.21270006457565915, \"functional effect\": -0.1915, \"times_seen\": 12.0}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 807, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.018582798834488122, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08856405843642937, \"functional effect\": 0.0096, \"times_seen\": 15.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.020534497367569984, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08619499132873595, \"functional effect\": -1.267, \"times_seen\": 5.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.004347269990933899, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08769446615201464, \"functional effect\": -0.1502, \"times_seen\": 4.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.09104496630426753, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.09312596708013371, \"functional effect\": -0.5554, \"times_seen\": 14.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.021550267403488477, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08874641265873871, \"functional effect\": -0.1551, \"times_seen\": 11.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.032704759802657246, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08547092739512181, \"functional effect\": -0.1412, \"times_seen\": 19.0}, {\"site\": 808, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.03501909685584874, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08533392688318193, \"functional effect\": -0.082, \"times_seen\": 6.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.026197230582315073, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08903272833338832, \"functional effect\": -0.1726, \"times_seen\": 8.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.9948109262802098, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.04387282513389503, \"functional effect\": -0.2061, \"times_seen\": 26.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.003671698980576003, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08765341106516202, \"functional effect\": -0.082, \"times_seen\": 10.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.024991677147270866, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.0859291044270584, \"functional effect\": -0.2985, \"times_seen\": 10.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.012146333295533015, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08669760878078066, \"functional effect\": -0.2188, \"times_seen\": 18.0}, {\"site\": 809, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.11033984917457472, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.09437981772988283, \"functional effect\": 0.0767, \"times_seen\": 35.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.00425584093950394, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08717308068837747, \"functional effect\": -2.1747, \"times_seen\": 1.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.04978126276007922, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.09050012587852131, \"functional effect\": -0.7802, \"times_seen\": 23.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01007584915494742, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08682212220157676, \"functional effect\": -1.1521, \"times_seen\": 26.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0035728663878918186, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08764740652719505, \"functional effect\": 0.0399, \"times_seen\": 11.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.8335262957852461, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.1558044821360726, \"functional effect\": -0.3491, \"times_seen\": 9.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0248568470016248, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08895004794458593, \"functional effect\": -0.5532, \"times_seen\": 7.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07379019155968954, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08307119709861124, \"functional effect\": 0.2633, \"times_seen\": 110.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.018038432143673615, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08634424986226465, \"functional effect\": -0.7006, \"times_seen\": 8.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03738755581293857, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.0851939499043152, \"functional effect\": -0.4102, \"times_seen\": 41.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.08711982790715582, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08230720394647471, \"functional effect\": -0.7068, \"times_seen\": 20.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.6725441390741859, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.05485390760811609, \"functional effect\": -1.0156, \"times_seen\": 30.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.00773952066449453, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08696283754765971, \"functional effect\": -0.6356, \"times_seen\": 15.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.28872401347682436, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.10680168842269029, \"functional effect\": -0.5575, \"times_seen\": 54.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.026867617873894103, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.0858174431650599, \"functional effect\": -2.0002, \"times_seen\": 6.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0023368797209752483, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08757234933816838, \"functional effect\": -0.3979, \"times_seen\": 7.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0816037509023502, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08262250407426817, \"functional effect\": -0.7631, \"times_seen\": 62.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08087512313402861, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08266424280197443, \"functional effect\": -0.017, \"times_seen\": 27.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0913622452526329, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08206552528419891, \"functional effect\": -0.6807, \"times_seen\": 12.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.019196916129956967, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08860176584933832, \"functional effect\": -0.7585, \"times_seen\": 13.0}, {\"site\": 810, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.057917413255367145, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.09101194770901039, \"functional effect\": -1.1562, \"times_seen\": 18.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0020434833293412613, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08730686223713395, \"functional effect\": 0.1731, \"times_seen\": 13.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0263740603175405, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08904364165755715, \"functional effect\": -0.1107, \"times_seen\": 5.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01728515118107953, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08638934495233233, \"functional effect\": -0.7483, \"times_seen\": 11.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0007318899833782073, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08738627137397664, \"functional effect\": 0.3921, \"times_seen\": 19.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0002254650435541702, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08741695170083323, \"functional effect\": -0.3986, \"times_seen\": 48.0}, {\"site\": 811, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02672453630338663, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.0858259546682581, \"functional effect\": -0.3278, \"times_seen\": 7.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.010456737126949278, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.086799203195041, \"functional effect\": -2.9512, \"times_seen\": 2.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.012937444304890215, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.08821817898752983, \"functional effect\": 0.2028, \"times_seen\": 19.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0338771624439109, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.0854014978670538, \"functional effect\": -0.5388, \"times_seen\": 8.0}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 812, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.011303226471487599, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.08674828942085709, \"functional effect\": -2.9839, \"times_seen\": 2.0}, {\"site\": 813, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004777923225189356, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": 0.08714154021303926, \"functional effect\": -3.0622, \"times_seen\": 1.0}, {\"site\": 813, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 813, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00496265918394008, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": 0.08713038252212975, \"functional effect\": -2.7514, \"times_seen\": 1.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005438320775664639, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08710166006602943, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.012442941311109549, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08818794621008724, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.016732339023276036, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08642245398077758, \"functional effect\": 0.0834, \"times_seen\": 25.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02337943525021463, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08602518567575378, \"functional effect\": 0.2055, \"times_seen\": 6.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.021738538446090576, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08612308492285824, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.015051964613257578, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08652317290080057, \"functional effect\": -0.2441, \"times_seen\": 3.0}, {\"site\": 815, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 815, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.00019015747713605377, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": 0.0874421390666687, \"functional effect\": -2.8434, \"times_seen\": 1.0}, {\"site\": 815, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0041424283670924295, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": 0.08717993377350884, \"functional effect\": -1.0312, \"times_seen\": 1.0}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.01309116564121635, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.08664084842234698, \"functional effect\": -1.8798, \"times_seen\": 2.0}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.21602852234265377, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.07527182829077317, \"functional effect\": -2.0993, \"times_seen\": 3.0}, {\"site\": 816, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.02786443875195772, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.08913567586477057, \"functional effect\": -2.1785, \"times_seen\": 1.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.030011113005064715, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.0892684050159639, \"functional effect\": -2.2577, \"times_seen\": 2.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.017724677277982225, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08851139579615597, \"functional effect\": -0.1336, \"times_seen\": 4.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.001936781086248524, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08731331972280064, \"functional effect\": -1.7228, \"times_seen\": 2.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.006777162760285657, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08702086595328727, \"functional effect\": -0.7693, \"times_seen\": 1.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.30983809576591576, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.07053309957741594, \"functional effect\": -0.8352, \"times_seen\": 37.0}, {\"site\": 817, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.015758218697575106, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08648082688326128, \"functional effect\": -2.0232, \"times_seen\": 2.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0023551325708656918, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08757345730278561, \"functional effect\": 0.1336, \"times_seen\": 11.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03207636948789112, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08550816381730447, \"functional effect\": -0.5161, \"times_seen\": 9.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.015205339121590592, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08651397501534737, \"functional effect\": -1.8992, \"times_seen\": 4.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008042496932842017, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08694457664784931, \"functional effect\": -1.7887, \"times_seen\": 2.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.002024532935622201, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.0873080090562698, \"functional effect\": -2.6414, \"times_seen\": 1.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.010147417106219449, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08681781531265285, \"functional effect\": -0.3849, \"times_seen\": 17.0}, {\"site\": 818, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008792386665626586, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.0868993959951259, \"functional effect\": -2.4362, \"times_seen\": 2.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.8066981155613747, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.15293393397684857, \"functional effect\": -0.815, \"times_seen\": 4.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.021235267983884483, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.0861531333837865, \"functional effect\": -0.6487, \"times_seen\": 6.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.008128494067360166, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.08792460997311612, \"functional effect\": -2.6705, \"times_seen\": 1.0}, {\"site\": 819, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.005394869476257066, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.0877581677922549, \"functional effect\": -1.7285, \"times_seen\": 1.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.026860069742438247, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.0858178921601825, \"functional effect\": -2.1796, \"times_seen\": 4.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02537725790324476, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.08590614172120561, \"functional effect\": -2.2322, \"times_seen\": 3.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.016144505328542596, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.08645767443983138, \"functional effect\": -2.1635, \"times_seen\": 1.0}, {\"site\": 820, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.9574202118953947, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.045024751829751145, \"functional effect\": 0.0194, \"times_seen\": 28.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.011948657516207464, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08670948876307852, \"functional effect\": 0.273, \"times_seen\": 14.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.013560138183520318, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08661268891917691, \"functional effect\": -1.0801, \"times_seen\": 3.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.011892204473106682, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08671288179496711, \"functional effect\": -0.5735, \"times_seen\": 7.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0036694417007245256, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08720852034603127, \"functional effect\": 0.1575, \"times_seen\": 1.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0031540660149841503, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08762196702806031, \"functional effect\": 0.2537, \"times_seen\": 7.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.015793665785754973, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.0864787020711907, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 821, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.1260392022697195, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.09541246376898292, \"functional effect\": -1.385, \"times_seen\": 12.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.022338112849904387, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08879488967541731, \"functional effect\": -1.0352, \"times_seen\": 13.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.005542512154468366, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08709536981472736, \"functional effect\": -1.034, \"times_seen\": 1.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005732032099123832, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08708392926418185, \"functional effect\": -2.8967, \"times_seen\": 1.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013699649936682759, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.0866043136884429, \"functional effect\": -0.0144, \"times_seen\": 4.0}, {\"site\": 822, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.034815421107819, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08534597494449614, \"functional effect\": -0.3462, \"times_seen\": 15.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.027589579218901168, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08911869552181943, \"functional effect\": -1.3643, \"times_seen\": 4.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.04852791724844225, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.0904215377727863, \"functional effect\": -2.364, \"times_seen\": 4.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.017685894136883734, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08850901642718693, \"functional effect\": -0.3888, \"times_seen\": 6.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06869565863541066, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08336506173919753, \"functional effect\": -0.625, \"times_seen\": 45.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.008744105327988326, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08796213621977249, \"functional effect\": -0.2696, \"times_seen\": 16.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.011695260063486014, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08672471990525783, \"functional effect\": -2.0156, \"times_seen\": 3.0}, {\"site\": 823, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.07787667879793125, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08283622778700711, \"functional effect\": -0.6488, \"times_seen\": 46.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.04856429133275258, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08453649191210547, \"functional effect\": -0.916, \"times_seen\": 8.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.040740942994126325, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08499615582940555, \"functional effect\": -0.2732, \"times_seen\": 48.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01644039597599162, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08643994415495511, \"functional effect\": -1.6449, \"times_seen\": 4.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.006697930000673773, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08702564526734552, \"functional effect\": -0.3136, \"times_seen\": 3.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0029592147279041826, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08725146295684136, \"functional effect\": -0.2808, \"times_seen\": 17.0}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 824, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009431963322301389, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08686088022721955, \"functional effect\": -2.4549, \"times_seen\": 2.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.05994959791203385, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.08387198136293188, \"functional effect\": 0.2707, \"times_seen\": 22.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.0296551254525144, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.04282589540877485, \"functional effect\": 0.0602, \"times_seen\": 15.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.02547181655907527, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.0859005113538337, \"functional effect\": 0.1565, \"times_seen\": 8.0}, {\"site\": 825, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.017698109156098873, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.08636462034831759, \"functional effect\": -2.2066, \"times_seen\": 1.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.024731411791994153, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08894231451335823, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.21699658735423805, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.07522133696787608, \"functional effect\": -0.4038, \"times_seen\": 20.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.005119759845797636, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.0871208950732106, \"functional effect\": -1.0234, \"times_seen\": 1.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02238202400658264, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08879759235723218, \"functional effect\": 0.0163, \"times_seen\": 4.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.013208040223666286, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08823472698787635, \"functional effect\": 0.0185, \"times_seen\": 53.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.023879900064458035, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08599534907769663, \"functional effect\": 0.059, \"times_seen\": 60.0}, {\"site\": 826, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.15035864410437813, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.09703445968836885, \"functional effect\": -0.3378, \"times_seen\": 95.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -4.181729070703005, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.004817676628065133, \"functional effect\": -0.7465, \"times_seen\": 18.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.30223486923606213, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.07090580118208409, \"functional effect\": -0.7345, \"times_seen\": 41.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.014786166780112292, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08653911514074968, \"functional effect\": -0.7527, \"times_seen\": 3.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.11222947150094274, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.0808870678654239, \"functional effect\": -0.3931, \"times_seen\": 32.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.012812738968391385, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.0882105538124739, \"functional effect\": -1.811, \"times_seen\": 5.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.019579655788041727, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08625205799989254, \"functional effect\": -2.2549, \"times_seen\": 2.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.016166139443290085, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08645637796263245, \"functional effect\": -1.3214, \"times_seen\": 5.0}, {\"site\": 827, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.011741756242419391, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08814509512591376, \"functional effect\": -1.3884, \"times_seen\": 22.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.010203030193243671, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.0868144687192817, \"functional effect\": 0.3178, \"times_seen\": 8.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.012280127129232935, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08817799439231365, \"functional effect\": -0.0031, \"times_seen\": 11.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.058220260981224486, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08397257773004116, \"functional effect\": 0.3553, \"times_seen\": 16.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.4218074565113168, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.06526597543449712, \"functional effect\": 0.0957, \"times_seen\": 74.0}, {\"site\": 828, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0055361651829316195, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08709575298167083, \"functional effect\": -0.7777, \"times_seen\": 42.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0027004694839979594, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08726711278235713, \"functional effect\": -0.0156, \"times_seen\": 1.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.09898753644984805, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08163291640113902, \"functional effect\": -0.1105, \"times_seen\": 49.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.027846136346812513, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08913454507353737, \"functional effect\": -0.7725, \"times_seen\": 1.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.4069415581991128, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.1159218078336644, \"functional effect\": -0.731, \"times_seen\": 29.0}, {\"site\": 829, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.028787475815381252, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08570331805973992, \"functional effect\": -1.0164, \"times_seen\": 6.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.009566468128372845, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08801229055397958, \"functional effect\": -1.5015, \"times_seen\": 3.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.029117334372775867, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08568372504772179, \"functional effect\": -0.0113, \"times_seen\": 5.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.030285513574923525, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08928538547972309, \"functional effect\": 0.1191, \"times_seen\": 16.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04796288540218904, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08457173937912046, \"functional effect\": -0.1784, \"times_seen\": 12.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.005235664393170614, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08711389615658896, \"functional effect\": -0.0873, \"times_seen\": 1.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.01907670582106242, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08628213229209286, \"functional effect\": -0.4468, \"times_seen\": 8.0}, {\"site\": 830, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027864750773567697, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08575815008608192, \"functional effect\": 0.098, \"times_seen\": 5.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04819505303221284, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.0845581306538202, \"functional effect\": 0.1099, \"times_seen\": 16.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.11240168002067916, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.09451479728778593, \"functional effect\": 0.0544, \"times_seen\": 8.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.02940975053078135, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08923120277945311, \"functional effect\": 0.1654, \"times_seen\": 17.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03663689943457479, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08523828915856474, \"functional effect\": -0.1605, \"times_seen\": 6.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06489831806809904, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08358477727589078, \"functional effect\": -0.0861, \"times_seen\": 23.0}, {\"site\": 831, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.002775429410475581, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08726257865266776, \"functional effect\": 0.3875, \"times_seen\": 15.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.04245385182969715, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08489529995437077, \"functional effect\": 0.2586, \"times_seen\": 26.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0016235650902145992, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08752906146647364, \"functional effect\": -0.5358, \"times_seen\": 4.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.020109699422226276, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08622037496517412, \"functional effect\": -0.2355, \"times_seen\": 5.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0216314901586375, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08612947551167738, \"functional effect\": -0.5423, \"times_seen\": 10.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.07421382782714529, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.09204583000290263, \"functional effect\": -0.4526, \"times_seen\": 13.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.016380571192400092, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08842897137507018, \"functional effect\": -0.0165, \"times_seen\": 61.0}, {\"site\": 832, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.002075055508391665, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.0875564579125262, \"functional effect\": -0.0234, \"times_seen\": 10.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.0329947552242836, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08945321232374913, \"functional effect\": -2.9421, \"times_seen\": 1.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.016425213486688617, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08843170773523656, \"functional effect\": -0.1667, \"times_seen\": 16.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 1.0626372935255899, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.182620374823891, \"functional effect\": -0.4189, \"times_seen\": 47.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.031889335646383854, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08551924998356097, \"functional effect\": -0.2839, \"times_seen\": 15.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.10517190857439214, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.09404234049020475, \"functional effect\": 0.1973, \"times_seen\": 37.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.045465093890292615, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.0847182883991223, \"functional effect\": 0.3236, \"times_seen\": 7.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.009337759479809506, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08799833918101639, \"functional effect\": -0.4693, \"times_seen\": 8.0}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 833, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.07268716463284858, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08313473429933843, \"functional effect\": -0.1702, \"times_seen\": 23.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.019995996345152773, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08865085420624766, \"functional effect\": -2.569, \"times_seen\": 3.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.16049453313925183, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.07822577263255014, \"functional effect\": -0.1285, \"times_seen\": 21.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.026053495744675723, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08586588416899005, \"functional effect\": -0.2107, \"times_seen\": 12.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01651933317762588, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08643521471426147, \"functional effect\": -1.874, \"times_seen\": 4.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.023134916862416345, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.0888439448563541, \"functional effect\": -0.9393, \"times_seen\": 2.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005529155578136596, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08709617615377134, \"functional effect\": -2.1686, \"times_seen\": 1.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0042983431371072965, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08717051258297696, \"functional effect\": 0.0472, \"times_seen\": 9.0}, {\"site\": 834, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.017681149226882353, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08636563563319483, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 2.611861764170311, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.5344563796757791, \"functional effect\": -1.8205, \"times_seen\": 3.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0487231077412582, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08452718638134282, \"functional effect\": -0.0613, \"times_seen\": 24.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.11879563499170341, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08051976161863987, \"functional effect\": -0.3981, \"times_seen\": 21.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.002177280636128563, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.0875626621254403, \"functional effect\": -1.2886, \"times_seen\": 2.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.2054467674457968, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.07582595528849968, \"functional effect\": -0.3667, \"times_seen\": 36.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03550909119674213, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08530494914346011, \"functional effect\": 0.3395, \"times_seen\": 21.0}, {\"site\": 835, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01720093144128882, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.0884792690749105, \"functional effect\": -0.8123, \"times_seen\": 5.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.00433267727425751, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08769357913570808, \"functional effect\": -0.9998, \"times_seen\": 2.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.11200163034998437, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.09448859260098182, \"functional effect\": -0.4425, \"times_seen\": 31.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 1.953196885324268, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.3385590129676914, \"functional effect\": -1.9107, \"times_seen\": 21.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.008008444398500819, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08791729388699968, \"functional effect\": -0.3722, \"times_seen\": 1.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04775963412090358, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.09037339811347976, \"functional effect\": -1.0207, \"times_seen\": 28.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.024214584857340547, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08597540168992127, \"functional effect\": -1.0149, \"times_seen\": 7.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006857789313346506, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08701600283515261, \"functional effect\": -0.6912, \"times_seen\": 4.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.04202225357043559, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08492070112642632, \"functional effect\": -1.0975, \"times_seen\": 11.0}, {\"site\": 836, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.035863127252899765, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08963124047640794, \"functional effect\": -0.5629, \"times_seen\": 24.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.004575190401840279, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08715378652380705, \"functional effect\": -2.8542, \"times_seen\": 1.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.012903483169097011, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.0866521204000768, \"functional effect\": -2.2287, \"times_seen\": 3.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005935458688370241, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08707165089813503, \"functional effect\": -1.4463, \"times_seen\": 1.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.017504819192606873, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.0863761921165495, \"functional effect\": -2.8114, \"times_seen\": 4.0}, {\"site\": 837, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.014028487269912304, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08828491951456062, \"functional effect\": -2.6818, \"times_seen\": 4.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.021581620705574102, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08613245278958563, \"functional effect\": 0.0767, \"times_seen\": 28.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.05688284664746054, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08405045849991788, \"functional effect\": -0.1726, \"times_seen\": 30.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.015707614838431607, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08648386033122486, \"functional effect\": -0.2628, \"times_seen\": 6.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.024396032804095934, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08892164076341627, \"functional effect\": -1.1094, \"times_seen\": 10.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.021597908262669125, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08613148038773788, \"functional effect\": -2.31, \"times_seen\": 2.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012190474057202165, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08669495621746365, \"functional effect\": -0.888, \"times_seen\": 1.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -3.7488431625195116, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.006503532112524725, \"functional effect\": -0.6282, \"times_seen\": 16.0}, {\"site\": 838, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011553626998575284, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08673323431092665, \"functional effect\": -0.2603, \"times_seen\": 11.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.011861285543938498, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.0867147401906113, \"functional effect\": -0.6956, \"times_seen\": 4.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.03169849955932005, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.08937287507066932, \"functional effect\": -0.1825, \"times_seen\": 48.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.08238972154458114, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.09256894358029986, \"functional effect\": -0.054, \"times_seen\": 16.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.05953368422788014, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.0911139667739514, \"functional effect\": 0.1613, \"times_seen\": 17.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.1324529218035977, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.07976111702606481, \"functional effect\": 0.4444, \"times_seen\": 21.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06101120891110561, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.08381028664333177, \"functional effect\": -0.0344, \"times_seen\": 21.0}, {\"site\": 839, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.08140360051818643, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.09250569182675912, \"functional effect\": -0.1463, \"times_seen\": 48.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.049924952013921844, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.09050913994094807, \"functional effect\": 0.0316, \"times_seen\": 8.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.08964003875323082, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.0930353231472528, \"functional effect\": -0.0822, \"times_seen\": 5.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.05344902271132806, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08425074907618187, \"functional effect\": 0.1265, \"times_seen\": 22.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.008637014243708196, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08795560704301388, \"functional effect\": -0.8541, \"times_seen\": 23.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.10548675807078614, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08126599397475999, \"functional effect\": -0.305, \"times_seen\": 12.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.05694431861791957, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.0909505810482752, \"functional effect\": 0.0364, \"times_seen\": 62.0}, {\"site\": 840, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.034508769561931024, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08536411755678891, \"functional effect\": -0.6549, \"times_seen\": 16.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.00309724559111841, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.0872431155110572, \"functional effect\": -0.5269, \"times_seen\": 9.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.037532781776874954, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08973503222266971, \"functional effect\": -0.11, \"times_seen\": 6.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.06110162121371223, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08380503449831772, \"functional effect\": -0.1671, \"times_seen\": 31.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.01780753942644797, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08851647965299275, \"functional effect\": -0.4068, \"times_seen\": 4.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02202098941819107, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08610622538754854, \"functional effect\": -0.8194, \"times_seen\": 8.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.09199944220398913, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08202928730262607, \"functional effect\": -0.5731, \"times_seen\": 22.0}, {\"site\": 841, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05919630335631413, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08391578604973486, \"functional effect\": -0.1602, \"times_seen\": 26.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.04971308492357832, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.09049584919022492, \"functional effect\": -3.0735, \"times_seen\": 3.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.003833542743549031, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08719860127453939, \"functional effect\": -2.6345, \"times_seen\": 22.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.4296078014029652, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.11775744239944058, \"functional effect\": -1.1338, \"times_seen\": 60.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.18323696439032175, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.07700230176504463, \"functional effect\": -1.6906, \"times_seen\": 42.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.4035022143315479, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.06609936085771256, \"functional effect\": -1.4706, \"times_seen\": 24.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.009097249570970248, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08798367030929984, \"functional effect\": -0.2424, \"times_seen\": 131.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.6636394462396488, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.13849653548562685, \"functional effect\": -0.777, \"times_seen\": 25.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03326674283522151, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08947007829917507, \"functional effect\": -1.1839, \"times_seen\": 41.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004460160682338, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08716073579237327, \"functional effect\": -0.6403, \"times_seen\": 30.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -2.288506484425434, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.017895936614994053, \"functional effect\": -1.7181, \"times_seen\": 72.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0785855052115135, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08279553860278725, \"functional effect\": -1.1965, \"times_seen\": 30.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.040916604572533884, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08994575161808366, \"functional effect\": -0.9794, \"times_seen\": 41.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.06370739246565646, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.09137794059527238, \"functional effect\": -0.4868, \"times_seen\": 44.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05620447756359331, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.09090395184300781, \"functional effect\": -0.9328, \"times_seen\": 33.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.5567676211668902, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.1286077927191868, \"functional effect\": -1.2054, \"times_seen\": 111.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.2192335915388803, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.10177929002585295, \"functional effect\": -0.5428, \"times_seen\": 157.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.5770039685910011, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.13042445544979422, \"functional effect\": -0.9665, \"times_seen\": 122.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.13581422500589035, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.0960611287699428, \"functional effect\": -0.9245, \"times_seen\": 183.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.09236765657697674, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.0932113858900577, \"functional effect\": -1.6397, \"times_seen\": 21.0}, {\"site\": 842, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.5213984140675797, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.06091257619378491, \"functional effect\": -1.367, \"times_seen\": 24.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.02859614814497852, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.0857146846362316, \"functional effect\": -2.5419, \"times_seen\": 10.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.04049485326065924, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08991946110389464, \"functional effect\": -2.79, \"times_seen\": 8.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.08576370450369998, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08238460852556999, \"functional effect\": -2.749, \"times_seen\": 29.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.03888101412369436, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08981893091110262, \"functional effect\": -2.0106, \"times_seen\": 29.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": 2.2567896506342713, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.4178543317511826, \"functional effect\": -1.4673, \"times_seen\": 22.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.013517598396444546, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08825366148938067, \"functional effect\": -1.0724, \"times_seen\": 152.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.008823361505573264, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08796696865766818, \"functional effect\": -1.6658, \"times_seen\": 25.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.04736183034380569, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.09034848229823852, \"functional effect\": -0.9476, \"times_seen\": 27.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.8887447474782382, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.16188341499907768, \"functional effect\": -2.8952, \"times_seen\": 15.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.5782440586781172, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.1305366119359854, \"functional effect\": -1.2763, \"times_seen\": 74.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.3168553808019724, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.07019085878765775, \"functional effect\": -1.2994, \"times_seen\": 27.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0030629847041865137, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08724518737096047, \"functional effect\": -2.338, \"times_seen\": 19.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.03511926428069379, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08532800228876909, \"functional effect\": -0.0578, \"times_seen\": 64.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.044399337920139684, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.0901631471679399, \"functional effect\": -1.8253, \"times_seen\": 23.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.15384483280704328, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.07858716473762577, \"functional effect\": -1.6611, \"times_seen\": 90.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.6880709652940075, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.05426671470255938, \"functional effect\": -1.6539, \"times_seen\": 134.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01337774611627135, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08662363958135437, \"functional effect\": -1.208, \"times_seen\": 117.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.6396231050304926, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.13621008705382356, \"functional effect\": -0.3525, \"times_seen\": 118.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.6595105916569138, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.13810073834562814, \"functional effect\": -1.5017, \"times_seen\": 24.0}, {\"site\": 843, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0798836806212423, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.09240828579158059, \"functional effect\": -1.3419, \"times_seen\": 17.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.04065824646047045, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08500102802256956, \"functional effect\": -2.5694, \"times_seen\": 12.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02844106079227246, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08572389931963946, \"functional effect\": -2.5871, \"times_seen\": 10.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.15080126610197508, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.07875313034098907, \"functional effect\": -0.6712, \"times_seen\": 39.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.05699529994965141, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.09095379507725533, \"functional effect\": -1.5409, \"times_seen\": 14.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.049704283035252976, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.09049529707636435, \"functional effect\": -1.2483, \"times_seen\": 4.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.047247858684276126, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.09034134512825542, \"functional effect\": -1.5557, \"times_seen\": 16.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.025839600539556237, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08901066072287106, \"functional effect\": -2.5772, \"times_seen\": 9.0}, {\"site\": 844, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.052703688101136716, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08429428649817161, \"functional effect\": -2.6551, \"times_seen\": 10.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.04977333783418887, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.09049962875002189, \"functional effect\": -2.2437, \"times_seen\": 31.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.6538622250571678, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.13756111037640736, \"functional effect\": -2.9922, \"times_seen\": 9.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.1454500684457323, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.09670487400561856, \"functional effect\": -2.7239, \"times_seen\": 27.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.1602827242483504, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.09770424604217298, \"functional effect\": -2.7619, \"times_seen\": 6.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01161679003549005, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.08672943710195126, \"functional effect\": -2.879, \"times_seen\": 5.0}, {\"site\": 845, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0027853564412234242, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.08726197821023429, \"functional effect\": -2.8739, \"times_seen\": 2.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.034503025083953684, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.08536445745763818, \"functional effect\": -2.2632, \"times_seen\": 19.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.00028492927702035447, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.08741334866987309, \"functional effect\": -2.4326, \"times_seen\": 10.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.08568331365217914, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.0927805147129868, \"functional effect\": -1.7226, \"times_seen\": 33.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.00999367669840642, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.08803835647314086, \"functional effect\": -1.5231, \"times_seen\": 36.0}, {\"site\": 846, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.43798968651627435, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.1184435903013388, \"functional effect\": -2.7332, \"times_seen\": 32.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.06109700405131991, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08380530270612449, \"functional effect\": -0.5665, \"times_seen\": 15.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.12953256594336882, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.07992273590713316, \"functional effect\": -0.7579, \"times_seen\": 37.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01290940656770668, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08665176462565376, \"functional effect\": -2.5023, \"times_seen\": 3.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.006014166754360037, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08706690072286564, \"functional effect\": -1.3863, \"times_seen\": 1.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0250361645554021, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.0889611045406468, \"functional effect\": -1.5783, \"times_seen\": 7.0}, {\"site\": 847, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05346426231033036, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08424985911620152, \"functional effect\": -0.7984, \"times_seen\": 38.0}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01202255939692937, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.08670504719365958, \"functional effect\": -2.8686, \"times_seen\": 3.0}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0036763198855239037, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.08720810457216906, \"functional effect\": -2.9829, \"times_seen\": 2.0}, {\"site\": 848, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0025331166386986115, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.08727723636793848, \"functional effect\": -3.064, \"times_seen\": 1.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.015639541405772794, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08648794116048704, \"functional effect\": -2.2183, \"times_seen\": 1.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.032431178767669336, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08941827501722006, \"functional effect\": -1.4741, \"times_seen\": 16.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0016404021933776433, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08753008298827529, \"functional effect\": -1.7418, \"times_seen\": 12.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.001733807616949093, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08753575019369017, \"functional effect\": 0.1227, \"times_seen\": 6.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1477481448967948, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.07891996910111725, \"functional effect\": -0.76, \"times_seen\": 32.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.903131400115231, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.04675132118775023, \"functional effect\": -0.281, \"times_seen\": 62.0}, {\"site\": 849, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.15098641140706312, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.07874302436822721, \"functional effect\": 0.0462, \"times_seen\": 58.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.010991951916685172, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08676700817127526, \"functional effect\": -0.5227, \"times_seen\": 15.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03091178211173338, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08557721647835591, \"functional effect\": -0.1194, \"times_seen\": 16.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.015440623074636407, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08649986691231228, \"functional effect\": -1.3369, \"times_seen\": 24.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.023143554023779565, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08884447675101179, \"functional effect\": -0.1023, \"times_seen\": 15.0}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 850, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0033263303567092235, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08722926332373049, \"functional effect\": -0.2598, \"times_seen\": 27.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.001296311210650464, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08750920905441459, \"functional effect\": -1.312, \"times_seen\": 1.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015032856582471955, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08652431887992525, \"functional effect\": -2.41, \"times_seen\": 9.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.01602717548559998, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08840731288814763, \"functional effect\": -2.0602, \"times_seen\": 20.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08625034373346775, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08235682384456426, \"functional effect\": -1.6936, \"times_seen\": 15.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0661878298199866, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.0835101007890059, \"functional effect\": -0.1584, \"times_seen\": 27.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01210192237945104, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08670027766046925, \"functional effect\": -2.4184, \"times_seen\": 3.0}, {\"site\": 851, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0750747484942332, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08299726450238715, \"functional effect\": -1.8308, \"times_seen\": 8.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00990656910474689, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.08683231015889298, \"functional effect\": -2.5032, \"times_seen\": 1.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.5179745854164035, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.061057306636316984, \"functional effect\": 0.3644, \"times_seen\": 38.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.08317018464225405, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.09261903468602505, \"functional effect\": -0.5995, \"times_seen\": 73.0}, {\"site\": 852, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0029454110575706832, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.08725229778066652, \"functional effect\": -1.4274, \"times_seen\": 6.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.011752045647616933, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08814572378533829, \"functional effect\": -2.8102, \"times_seen\": 5.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": 2.6674969366667995, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.5554693769202189, \"functional effect\": -0.5312, \"times_seen\": 1.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.6409155984007161, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.1363321707332399, \"functional effect\": -0.9125, \"times_seen\": 92.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.005423248661922886, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08775989409598671, \"functional effect\": -1.5977, \"times_seen\": 26.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.010468686590103271, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08679848426307302, \"functional effect\": -2.5873, \"times_seen\": 3.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02779243936379346, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08576244860238036, \"functional effect\": -2.3979, \"times_seen\": 15.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.06083375966015082, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08382059581250756, \"functional effect\": -2.1267, \"times_seen\": 41.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03761938596643263, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08518026098245131, \"functional effect\": -2.3544, \"times_seen\": 14.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.12510530757679003, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.080168374844396, \"functional effect\": 0.0791, \"times_seen\": 70.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.011102097750663646, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08810602223841456, \"functional effect\": -2.1387, \"times_seen\": 18.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07930056577172555, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08275451180709907, \"functional effect\": -2.0955, \"times_seen\": 61.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.5420228835225575, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.06004797740968487, \"functional effect\": -2.4447, \"times_seen\": 16.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.14544846160468783, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.09670476629798123, \"functional effect\": -1.7298, \"times_seen\": 64.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0059789622154681815, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.0877937049535811, \"functional effect\": -2.5298, \"times_seen\": 14.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0035946582597644857, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08764873044903869, \"functional effect\": -2.2424, \"times_seen\": 17.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.08692087741573695, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.09286013726776636, \"functional effect\": -0.6447, \"times_seen\": 224.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.6306506190213887, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.05647012861187776, \"functional effect\": -1.9095, \"times_seen\": 79.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.002970935558157507, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08725075410611163, \"functional effect\": -2.1544, \"times_seen\": 24.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.25597779978389257, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.07321609028838072, \"functional effect\": -0.8934, \"times_seen\": 83.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.029947498975641407, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08926446891194631, \"functional effect\": -0.3892, \"times_seen\": 43.0}, {\"site\": 853, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.17132489061181685, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.09845492848144032, \"functional effect\": -0.8007, \"times_seen\": 50.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005426160086135663, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08710239426187794, \"functional effect\": -2.1181, \"times_seen\": 1.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0009653982134640736, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08748913924546557, \"functional effect\": -2.9628, \"times_seen\": 2.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0012537628653126005, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08735466644250076, \"functional effect\": -1.1154, \"times_seen\": 1.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005139864823129253, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08711968099028501, \"functional effect\": -2.289, \"times_seen\": 1.0}, {\"site\": 854, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.006114275356710064, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08706085936062649, \"functional effect\": -1.0823, \"times_seen\": 2.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.002273064365613296, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08756847579813536, \"functional effect\": -2.5774, \"times_seen\": 1.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.05404835551668448, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08421575640655111, \"functional effect\": -2.1564, \"times_seen\": 24.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.01620204466878545, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08841802939519082, \"functional effect\": -2.7938, \"times_seen\": 2.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.017387560020642435, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08849071558849925, \"functional effect\": 0.4444, \"times_seen\": 39.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.012556802019557722, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08667294549862416, \"functional effect\": -0.3922, \"times_seen\": 3.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006555994534727194, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08703420746017884, \"functional effect\": -1.7526, \"times_seen\": 2.0}, {\"site\": 855, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.06478811113513427, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.09144641719006709, \"functional effect\": -0.1563, \"times_seen\": 18.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.21709879589686734, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07521600805866452, \"functional effect\": -2.6513, \"times_seen\": 8.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.21896672449398008, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07511868519226743, \"functional effect\": -0.5444, \"times_seen\": 104.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.15780877980756303, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07837153511444324, \"functional effect\": -1.5342, \"times_seen\": 15.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.18505341755441193, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07690541153254857, \"functional effect\": -0.6204, \"times_seen\": 27.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.012160042471628685, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08817065508408187, \"functional effect\": -0.2778, \"times_seen\": 11.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.12059468604240822, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08041941547828112, \"functional effect\": -0.4182, \"times_seen\": 26.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0794905878101748, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08274361266000492, \"functional effect\": 0.4027, \"times_seen\": 39.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.3085792611903851, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.10828171948145257, \"functional effect\": -0.7925, \"times_seen\": 35.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03072150871277568, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08558850378523968, \"functional effect\": -1.5402, \"times_seen\": 73.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.17081912122132542, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.09842041892792411, \"functional effect\": -2.407, \"times_seen\": 25.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.05601420384602286, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.09089196352128182, \"functional effect\": -1.3142, \"times_seen\": 73.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.5276205639933227, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.1260355747060641, \"functional effect\": -1.0852, \"times_seen\": 36.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.052295035307586515, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08431816678736957, \"functional effect\": -0.2957, \"times_seen\": 82.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.025941267283880996, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08587256400815987, \"functional effect\": -2.7071, \"times_seen\": 11.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.04175150266827596, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08493663970902043, \"functional effect\": -1.4345, \"times_seen\": 27.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.21580973997635008, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07528324400718575, \"functional effect\": -1.6237, \"times_seen\": 60.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.11485517499686236, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08073998736857911, \"functional effect\": -0.0987, \"times_seen\": 123.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.00986268795070181, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08803036343911018, \"functional effect\": -0.8602, \"times_seen\": 67.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.11594469354427918, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08067903581391224, \"functional effect\": -0.871, \"times_seen\": 23.0}, {\"site\": 856, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06505628856225476, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08357562551108369, \"functional effect\": -0.9994, \"times_seen\": 38.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0248250302962262, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08593903073950726, \"functional effect\": -0.6694, \"times_seen\": 6.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.463102175711352, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.12052334481921345, \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.002878147601790592, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08725636588080087, \"functional effect\": 0.1868, \"times_seen\": 39.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.11265844798554511, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08086302016938576, \"functional effect\": 0.2905, \"times_seen\": 100.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.9932786499945954, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.043919446907745865, \"functional effect\": 0.4342, \"times_seen\": 18.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09894464727364055, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.0936372901320195, \"functional effect\": -0.421, \"times_seen\": 16.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.005948963626656781, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08779187943966514, \"functional effect\": -1.7347, \"times_seen\": 7.0}, {\"site\": 857, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04820667055762278, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.08455744973910963, \"functional effect\": -1.5722, \"times_seen\": 6.0}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.06288670621708078, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.0913259744546989, \"functional effect\": -0.4802, \"times_seen\": 16.0}, {\"site\": 858, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.040815882717037635, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.0899394722683232, \"functional effect\": -1.3433, \"times_seen\": 13.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.10533746048550419, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.09405313264105149, \"functional effect\": -0.7611, \"times_seen\": 24.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.08314293798453416, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08253440251924614, \"functional effect\": -1.0231, \"times_seen\": 15.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.005661849201166386, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08708816574591301, \"functional effect\": -1.3384, \"times_seen\": 3.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009228932189093255, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08687310505881994, \"functional effect\": -1.0846, \"times_seen\": 4.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.014356147362643441, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08830497276857213, \"functional effect\": -0.919, \"times_seen\": 5.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03745082856055141, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.0851902136073613, \"functional effect\": -1.0717, \"times_seen\": 33.0}, {\"site\": 859, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.023968274800987063, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08599008144778386, \"functional effect\": -0.7747, \"times_seen\": 17.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.017635726921753834, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.08636835484127359, \"functional effect\": -1.96, \"times_seen\": 5.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06492362249993823, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.0835833112371988, \"functional effect\": -2.6658, \"times_seen\": 8.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.003828319907623743, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.0871989169509636, \"functional effect\": -0.6719, \"times_seen\": 1.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1590781438648652, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.07830260976648201, \"functional effect\": -0.9811, \"times_seen\": 17.0}, {\"site\": 860, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006957525818181686, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.08700998744606403, \"functional effect\": -2.9445, \"times_seen\": 1.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.04126614684811202, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.08996754669660327, \"functional effect\": -2.6214, \"times_seen\": 5.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.016249759889231816, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.08645136698584056, \"functional effect\": -1.0673, \"times_seen\": 2.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01471391509595424, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.0865434492191295, \"functional effect\": -0.7441, \"times_seen\": 4.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.004104377207638029, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.0876797031152038, \"functional effect\": -1.5503, \"times_seen\": 13.0}, {\"site\": 861, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.013736054700421132, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.086602128354945, \"functional effect\": -2.7774, \"times_seen\": 3.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.006773177313772617, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08784204939243592, \"functional effect\": -2.018, \"times_seen\": 5.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.01423861199042687, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08829777891624922, \"functional effect\": -0.432, \"times_seen\": 24.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.004089798828295093, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08718311415693526, \"functional effect\": -0.1443, \"times_seen\": 3.0}, {\"site\": 862, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01932686184217449, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08626717270387362, \"functional effect\": -1.6943, \"times_seen\": 1.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.010827181029393776, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.0867769184384939, \"functional effect\": -1.8864, \"times_seen\": 4.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.007866871438819248, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08695516143067145, \"functional effect\": -2.383, \"times_seen\": 2.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.004101267853889912, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08718242107810371, \"functional effect\": -1.4373, \"times_seen\": 1.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0031799263137077447, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08723811575925004, \"functional effect\": -3.0869, \"times_seen\": 1.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00511607125808433, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08712111781846503, \"functional effect\": -2.9688, \"times_seen\": 2.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.08077794186067185, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.09246558325406981, \"functional effect\": -0.8521, \"times_seen\": 4.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.039347737424329565, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08507827596586104, \"functional effect\": -0.8765, \"times_seen\": 21.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.012920352663475965, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08821713387092005, \"functional effect\": -1.2687, \"times_seen\": 6.0}, {\"site\": 863, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01271047969784133, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08666371347989078, \"functional effect\": -1.1439, \"times_seen\": 5.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.1680827075246997, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.07781540699081547, \"functional effect\": -1.6771, \"times_seen\": 15.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.04385064581094079, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.09012886244420076, \"functional effect\": -0.9305, \"times_seen\": 25.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.09216461256119005, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08201989652304569, \"functional effect\": -0.5879, \"times_seen\": 47.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01551715749532824, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08649527824913708, \"functional effect\": -0.928, \"times_seen\": 6.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.030462712294416872, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.0892963526122002, \"functional effect\": -1.4787, \"times_seen\": 7.0}, {\"site\": 864, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12051598599091616, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08042380253485852, \"functional effect\": -1.1107, \"times_seen\": 51.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.005894381572020878, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08707413007991072, \"functional effect\": 0.4116, \"times_seen\": 11.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0027579839252685635, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08759791431617053, \"functional effect\": -0.8784, \"times_seen\": 12.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -1.01223878086829, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.043346026697782127, \"functional effect\": -0.0776, \"times_seen\": 23.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.10230429060397639, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.0814454579909593, \"functional effect\": -0.8603, \"times_seen\": 28.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03157333769762847, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08553798358046742, \"functional effect\": -0.0227, \"times_seen\": 19.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 1.1139034481513117, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.1892264666901331, \"functional effect\": -0.1754, \"times_seen\": 16.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.07677967763455762, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.09220968023716766, \"functional effect\": 0.0639, \"times_seen\": 11.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.034591827374756405, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08535920317599029, \"functional effect\": -0.2828, \"times_seen\": 10.0}, {\"site\": 865, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.07424740861823093, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08304487445286045, \"functional effect\": -0.0615, \"times_seen\": 19.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.027333386902800644, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08910287131969281, \"functional effect\": -1.9106, \"times_seen\": 5.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.007145794183313424, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08786474002060356, \"functional effect\": -2.1834, \"times_seen\": 43.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.001723844359290372, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08732620781358548, \"functional effect\": -2.8871, \"times_seen\": 1.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.021310780019657225, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08614862416454473, \"functional effect\": -1.9617, \"times_seen\": 13.0}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 866, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010310927946783567, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08680797619271495, \"functional effect\": -2.0013, \"times_seen\": 2.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.006776040929687091, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08702093362019214, \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.05538181820049513, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08413795293224101, \"functional effect\": -2.5393, \"times_seen\": 18.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.00344151169091664, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08722229942520314, \"functional effect\": -0.2995, \"times_seen\": 8.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.013186813077026276, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08823342875252066, \"functional effect\": -2.73, \"times_seen\": 3.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.06217486845276806, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.09128092457221154, \"functional effect\": -1.9914, \"times_seen\": 7.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.036813861605203446, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08522783440050746, \"functional effect\": -1.265, \"times_seen\": 16.0}, {\"site\": 867, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.8883091828406136, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.0472341191193149, \"functional effect\": -0.5048, \"times_seen\": 13.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.04338308557414784, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.09009965748877678, \"functional effect\": -0.8446, \"times_seen\": 16.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.010049092148359756, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.08682373246679063, \"functional effect\": -2.239, \"times_seen\": 8.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03916425780241301, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.08508909677146631, \"functional effect\": -1.8396, \"times_seen\": 40.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08897012492352789, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.08220171030337887, \"functional effect\": -1.8136, \"times_seen\": 42.0}, {\"site\": 868, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.7034944379595798, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.14237589186042032, \"functional effect\": -0.9823, \"times_seen\": 63.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.012728722361683443, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08666261763707442, \"functional effect\": -1.2791, \"times_seen\": 1.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.020605913169684322, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08619072463902418, \"functional effect\": -2.6765, \"times_seen\": 18.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.026682032492604327, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.0890626518367139, \"functional effect\": -2.8286, \"times_seen\": 14.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.012701890863502159, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08820377649861809, \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 869, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004143289168024053, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08717988175659348, \"functional effect\": -2.8946, \"times_seen\": 11.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.03134938753177542, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08935125070105329, \"functional effect\": -2.8302, \"times_seen\": 2.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.016553883344988994, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08843959505889396, \"functional effect\": -2.2976, \"times_seen\": 5.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.02633014457248471, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08584942024688885, \"functional effect\": -2.5511, \"times_seen\": 4.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.013141530505321247, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08663782382028919, \"functional effect\": -2.6485, \"times_seen\": 3.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.030751055806150465, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08931420156599618, \"functional effect\": -2.876, \"times_seen\": 3.0}, {\"site\": 870, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.03389292609377351, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.0895089200666565, \"functional effect\": -1.3152, \"times_seen\": 28.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.080627926145195, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.041339204014455885, \"functional effect\": -0.4757, \"times_seen\": 60.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.008465612179826757, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08691908118210218, \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07417925835785948, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08304879743265248, \"functional effect\": -2.4005, \"times_seen\": 26.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0021734407355513056, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08756242906754527, \"functional effect\": -0.8241, \"times_seen\": 13.0}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 871, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.006253991449493166, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08705242846304666, \"functional effect\": -0.5853, \"times_seen\": 10.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.04585385982555147, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08469546226714074, \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.003829799362097969, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08719882753029047, \"functional effect\": -2.9798, \"times_seen\": 5.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0027756801205965132, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08759898880472514, \"functional effect\": -2.3565, \"times_seen\": 7.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.022722743387585825, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08606435188684024, \"functional effect\": -2.6843, \"times_seen\": 5.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.015512591017670092, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08837578514565943, \"functional effect\": -2.8007, \"times_seen\": 6.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02416234341077369, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08597851500253942, \"functional effect\": -1.976, \"times_seen\": 7.0}, {\"site\": 872, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005696858245025512, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08708605245354319, \"functional effect\": -2.1349, \"times_seen\": 4.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.002188540180769134, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.08729808434469802, \"functional effect\": -1.8838, \"times_seen\": 3.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06298495589268832, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.08369570442625435, \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0019056011387167224, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.08754617441347957, \"functional effect\": -1.912, \"times_seen\": 18.0}, {\"site\": 873, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 1.0521272128310255, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.18129481364400205, \"functional effect\": -2.9086, \"times_seen\": 20.0}, {\"site\": 874, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 874, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.3670531075138591, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": 0.06779060887008029, \"functional effect\": -0.3375, \"times_seen\": 23.0}, {\"site\": 874, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.09939722468409438, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": 0.08160973804656323, \"functional effect\": -2.0821, \"times_seen\": 4.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.055245005206857226, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.08414593224229683, \"functional effect\": -0.2397, \"times_seen\": 19.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0062536223715932236, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.08705245073326363, \"functional effect\": 0.193, \"times_seen\": 2.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.1081367292414633, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.09423580158714905, \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 875, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03830092506025734, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.0851400307425761, \"functional effect\": -0.3973, \"times_seen\": 17.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.040289129139701445, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08990663976417447, \"functional effect\": -1.3348, \"times_seen\": 5.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.014831539464150025, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08653639353287466, \"functional effect\": -2.5662, \"times_seen\": 3.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.07788653331336395, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.0828356619653511, \"functional effect\": -1.8807, \"times_seen\": 5.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.01727877623159941, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08638972668853497, \"functional effect\": -2.1241, \"times_seen\": 11.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.19901786231195973, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.10036305584245861, \"functional effect\": -2.8638, \"times_seen\": 6.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.028658976419772796, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08571095190800677, \"functional effect\": -0.6351, \"times_seen\": 23.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.1335140605703524, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.07970247227299275, \"functional effect\": -1.6446, \"times_seen\": 62.0}, {\"site\": 876, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.010612273796567677, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08678984589436892, \"functional effect\": -0.8753, \"times_seen\": 50.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01887748551796489, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08629404772739341, \"functional effect\": -2.5512, \"times_seen\": 5.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.025648817466498698, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08899889066466912, \"functional effect\": -2.8455, \"times_seen\": 4.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0433003118679884, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.09009448822679061, \"functional effect\": -2.9677, \"times_seen\": 4.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005023096784807649, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08712673251929923, \"functional effect\": -2.2973, \"times_seen\": 1.0}, {\"site\": 877, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.006089501032641488, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08706235440455584, \"functional effect\": -2.0185, \"times_seen\": 2.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.6719828240998457, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.13929980760241295, \"functional effect\": -1.2638, \"times_seen\": 35.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.09254540042740987, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.09322287048714857, \"functional effect\": -1.4343, \"times_seen\": 13.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.006206406680577266, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.08705529978227194, \"functional effect\": -0.3877, \"times_seen\": 36.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0026122309512827406, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.08727245040206014, \"functional effect\": -2.9447, \"times_seen\": 2.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0011159460280305976, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.08749826937039606, \"functional effect\": -2.7151, \"times_seen\": 2.0}, {\"site\": 878, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.005027381571704077, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.08773581659730087, \"functional effect\": -0.3617, \"times_seen\": 15.0}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0165872916217494, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.08643114326173885, \"functional effect\": -2.4807, \"times_seen\": 4.0}, {\"site\": 879, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.031249391425518747, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.08934505780008012, \"functional effect\": -1.8263, \"times_seen\": 23.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.11754733576250061, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.09485250480209236, \"functional effect\": -2.1703, \"times_seen\": 16.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.7062709210466765, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.05358642666072652, \"functional effect\": 0.1604, \"times_seen\": 66.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005844975307195679, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08707711205536078, \"functional effect\": -1.9154, \"times_seen\": 1.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0030642875266294746, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08724510858442998, \"functional effect\": -2.556, \"times_seen\": 5.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0144319657076726, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.0883096136057776, \"functional effect\": -2.1828, \"times_seen\": 34.0}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 880, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0355388533586755, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08961109636809454, \"functional effect\": 0.3069, \"times_seen\": 16.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0014120118310818276, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08751622736077862, \"functional effect\": -0.6929, \"times_seen\": 17.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.2697921350468284, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.10540933056206275, \"functional effect\": -0.0416, \"times_seen\": 71.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.016402279351217942, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.0884303019713103, \"functional effect\": -0.9622, \"times_seen\": 58.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.002158597153380067, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.087299896228695, \"functional effect\": -3.0951, \"times_seen\": 3.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.012444912189225128, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08818806668448208, \"functional effect\": -2.5014, \"times_seen\": 5.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.003224275262289039, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08723543407037253, \"functional effect\": 0.2088, \"times_seen\": 1.0}, {\"site\": 881, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.023006401806928284, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08604743183271267, \"functional effect\": -0.6158, \"times_seen\": 5.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.05606429865550326, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.0908951196246291, \"functional effect\": -1.9734, \"times_seen\": 12.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.046113419398984, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.0846802258242383, \"functional effect\": 0.3778, \"times_seen\": 18.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.015054363992643018, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.08652302900223649, \"functional effect\": -2.6946, \"times_seen\": 3.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05380731920342332, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.08422982781504727, \"functional effect\": -1.3894, \"times_seen\": 10.0}, {\"site\": 882, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.00405312125811428, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.08767658809333322, \"functional effect\": -1.2089, \"times_seen\": 5.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.02656029987718551, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08583572565244466, \"functional effect\": -2.5819, \"times_seen\": 6.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.07250433669273194, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08314527035506443, \"functional effect\": -0.9062, \"times_seen\": 10.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.011588128291520578, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08813570933821106, \"functional effect\": 0.0434, \"times_seen\": 2.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.4121153227555107, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.06570591327771234, \"functional effect\": 0.0778, \"times_seen\": 29.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.060573544602357844, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08383571567340259, \"functional effect\": -2.9759, \"times_seen\": 16.0}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 883, \"wildtype\": \"W\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0014911553368769693, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.0875210284662357, \"functional effect\": -0.2983, \"times_seen\": 9.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.05619946516959511, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08409028128361004, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01593811521732445, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08647004384914449, \"functional effect\": -1.8786, \"times_seen\": 10.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0681818251250993, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08339475851519171, \"functional effect\": -2.6117, \"times_seen\": 19.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.011868302364601313, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08815282711977328, \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -1.7961187447587226, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.025175488833157043, \"functional effect\": -2.577, \"times_seen\": 13.0}, {\"site\": 884, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0955156462210198, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08182960511262778, \"functional effect\": 0.3901, \"times_seen\": 19.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0046995741744639006, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08714627277408306, \"functional effect\": -1.1316, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.005122510063381313, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08712072899432187, \"functional effect\": -0.635, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.009461406941777968, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08685910752229244, \"functional effect\": -0.454, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0022293665177011714, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08729561396081552, \"functional effect\": -0.1789, \"times_seen\": 31.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08367586590946359, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08250392014863409, \"functional effect\": -1.6337, \"times_seen\": 33.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.003547072169289511, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08721591769479041, \"functional effect\": -3.006, \"times_seen\": 1.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004104238170372133, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08718224158132278, \"functional effect\": -0.3042, \"times_seen\": 20.0}, {\"site\": 885, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010645158850954984, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08678786761330913, \"functional effect\": -0.2256, \"times_seen\": 3.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.04281334681390829, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.09006408300425116, \"functional effect\": -2.8258, \"times_seen\": 2.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.044363683773958766, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08478299036620643, \"functional effect\": -1.119, \"times_seen\": 15.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0013432253781853233, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.0875120547621558, \"functional effect\": -2.6001, \"times_seen\": 2.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.020314630536480513, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08867043583092411, \"functional effect\": -3.051, \"times_seen\": 2.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0402229600149541, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08502667819575932, \"functional effect\": -2.6684, \"times_seen\": 11.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07760171159183038, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08285201727556826, \"functional effect\": -0.7051, \"times_seen\": 12.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03932773350975831, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08507945564023094, \"functional effect\": -3.131, \"times_seen\": 4.0}, {\"site\": 886, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.003234174761947899, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08723483547942817, \"functional effect\": -2.4742, \"times_seen\": 3.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0029476064889255335, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.08725216500396794, \"functional effect\": -1.2195, \"times_seen\": 8.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 3.7628070544730396e-05, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.08743289470651348, \"functional effect\": -3.2528, \"times_seen\": 1.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.1502571489685516, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.19405526690138045, \"functional effect\": 0.1666, \"times_seen\": 25.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.019976504105319173, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.08864965645343838, \"functional effect\": -1.1744, \"times_seen\": 31.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.3461198156206978, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.11113631090035965, \"functional effect\": -0.4164, \"times_seen\": 81.0}, {\"site\": 887, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.24571502828001668, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.0737387779776787, \"functional effect\": 0.4444, \"times_seen\": 109.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.019831711054001912, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08864075976370692, \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0029573167195928456, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08725157774486385, \"functional effect\": -2.9939, \"times_seen\": 3.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0056506451372141655, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.0870888420809247, \"functional effect\": -2.7203, \"times_seen\": 1.0}, {\"site\": 888, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.015590836331094798, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08649086102408902, \"functional effect\": -2.1703, \"times_seen\": 9.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00325941201714122, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08723330948225878, \"functional effect\": -1.5322, \"times_seen\": 3.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.035350986696412734, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08959942803831562, \"functional effect\": -2.5049, \"times_seen\": 2.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.005530118528893257, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.087096118020002, \"functional effect\": -1.2289, \"times_seen\": 1.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.06501143076709417, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.09146057358508598, \"functional effect\": -2.3039, \"times_seen\": 2.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05659641712494521, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08406714735100815, \"functional effect\": -0.3493, \"times_seen\": 27.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.1064467800894457, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.09412547995208762, \"functional effect\": -0.5448, \"times_seen\": 28.0}, {\"site\": 889, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.32549488379428115, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.10955879663186191, \"functional effect\": -0.6734, \"times_seen\": 93.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -5.1878751618278605, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.0023985981395686132, \"functional effect\": -2.9218, \"times_seen\": 1.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.1564647715391883, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.07844457970589072, \"functional effect\": -0.0444, \"times_seen\": 3.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.10812619017680158, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.08111745254689784, \"functional effect\": -2.1832, \"times_seen\": 9.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06272131300507443, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.08371100065510378, \"functional effect\": -2.3667, \"times_seen\": 7.0}, {\"site\": 890, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03908716704445997, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.08509364364938389, \"functional effect\": -2.3519, \"times_seen\": 15.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.028425773751505554, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08572480766939422, \"functional effect\": -0.4678, \"times_seen\": 11.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.001556548419529846, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08752499562450375, \"functional effect\": -2.6892, \"times_seen\": 9.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.02398721267662463, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08889644638397104, \"functional effect\": -2.8638, \"times_seen\": 3.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005529261370599726, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08709616976703097, \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 891, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.007252538168397602, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08699219685564132, \"functional effect\": -2.0644, \"times_seen\": 2.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005874229892316372, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08707534634681749, \"functional effect\": -1.3112, \"times_seen\": 1.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03940664558161603, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.0850748021186511, \"functional effect\": -0.7551, \"times_seen\": 18.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0052545909219517415, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08711275332820098, \"functional effect\": -2.1146, \"times_seen\": 14.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.005445240603914436, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08710124228745159, \"functional effect\": -2.9371, \"times_seen\": 1.0}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 892, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005751383040096247, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08708276121090268, \"functional effect\": -2.7823, \"times_seen\": 1.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009552733951169455, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.0868536092491089, \"functional effect\": -1.1891, \"times_seen\": 2.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.005914256512712456, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.08707293053239612, \"functional effect\": -1.5844, \"times_seen\": 9.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.014950859630980086, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.08834138162479246, \"functional effect\": -2.6707, \"times_seen\": 3.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.02562774960797607, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.08899759101207895, \"functional effect\": -2.4205, \"times_seen\": 12.0}, {\"site\": 893, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01301274254756926, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.0882227834583394, \"functional effect\": -1.8276, \"times_seen\": 4.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.011452171842138951, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08673933389747784, \"functional effect\": -2.9962, \"times_seen\": 1.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.4904778765001496, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.03111608729834304, \"functional effect\": -2.696, \"times_seen\": 3.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.020023421465314425, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08622553138425491, \"functional effect\": -2.8016, \"times_seen\": 2.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.010976507328212336, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08809835270977324, \"functional effect\": -2.7618, \"times_seen\": 2.0}, {\"site\": 894, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.003224972728783505, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08762627364743956, \"functional effect\": -3.0526, \"times_seen\": 3.0}, {\"site\": 895, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 895, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004238295673301679, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": 0.08717414084604305, \"functional effect\": -2.7561, \"times_seen\": 2.0}, {\"site\": 895, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00397540391874083, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": 0.08719002739888217, \"functional effect\": -0.7948, \"times_seen\": 1.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004697679848429016, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08714638720128844, \"functional effect\": -2.8743, \"times_seen\": 1.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.029645095126411638, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08924576011394787, \"functional effect\": -1.9038, \"times_seen\": 6.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.07692846907334261, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.09221919071452438, \"functional effect\": -1.4036, \"times_seen\": 14.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.12751908862327868, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08003435683776089, \"functional effect\": -1.3045, \"times_seen\": 32.0}, {\"site\": 896, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004015833641154051, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08718758404175354, \"functional effect\": -0.7626, \"times_seen\": 18.0}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.3661642038010169, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.11269118316368841, \"functional effect\": -1.8462, \"times_seen\": 31.0}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.2692264766741449, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.10536800929798502, \"functional effect\": -1.6964, \"times_seen\": 5.0}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 897, \"wildtype\": \"M\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.019210246209048844, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.08860258450745341, \"functional effect\": -2.7554, \"times_seen\": 7.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.03015203239502048, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08927712499019086, \"functional effect\": -2.6303, \"times_seen\": 1.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.029373254987394442, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08566852690387369, \"functional effect\": -2.9477, \"times_seen\": 4.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.09110153457108565, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.0931296186334312, \"functional effect\": -2.5577, \"times_seen\": 7.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.030076610492494032, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08927245783987578, \"functional effect\": -2.8476, \"times_seen\": 1.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.008229603668250384, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08693330131898963, \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 898, \"wildtype\": \"Q\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.002299974405357237, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08729134167325724, \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.007761311695624124, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.08696152403681022, \"functional effect\": -2.8048, \"times_seen\": 2.0}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.008039204929957614, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.08791916844221655, \"functional effect\": -1.6681, \"times_seen\": 7.0}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 899, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01267465151854603, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.08820211114984733, \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.002403557751869, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.08757639682331753, \"functional effect\": -2.7687, \"times_seen\": 1.0}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.021356520654104424, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.0887344952583317, \"functional effect\": -2.7799, \"times_seen\": 5.0}, {\"site\": 900, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.006204691393240826, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.08705540328643452, \"functional effect\": -2.598, \"times_seen\": 4.0}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.018286183386139358, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.08854585170051903, \"functional effect\": -1.5884, \"times_seen\": 3.0}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.021493589474370675, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.08613770863159485, \"functional effect\": 0.1966, \"times_seen\": 18.0}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 1.3414289817748712, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.2215510897393556, \"functional effect\": -0.7952, \"times_seen\": 21.0}, {\"site\": 901, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 1.343209236426571, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 0.2218246477667337, \"functional effect\": -2.9103, \"times_seen\": 7.0}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 3.9968776568592546, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 1.3958655650754823, \"functional effect\": -2.5305, \"times_seen\": 5.0}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 902, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.15235723685125832, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 0.09716897651484359, \"functional effect\": -2.7124, \"times_seen\": 1.0}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05000090641242419, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.08445235358183074, \"functional effect\": -2.4218, \"times_seen\": 2.0}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.025943763592016396, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.08901708755361125, \"functional effect\": -1.3472, \"times_seen\": 1.0}, {\"site\": 903, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007764586931471653, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.08696132661520031, \"functional effect\": -2.4569, \"times_seen\": 1.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.007716150504521103, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08789948341117798, \"functional effect\": -1.1061, \"times_seen\": 7.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.010465227367253567, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08679869238443723, \"functional effect\": -1.3226, \"times_seen\": 6.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.005127549644105531, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08712042466723456, \"functional effect\": -2.0818, \"times_seen\": 1.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004906264110924876, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08713378852283338, \"functional effect\": -2.0047, \"times_seen\": 1.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.014504988257287453, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08655598309360744, \"functional effect\": 0.378, \"times_seen\": 8.0}, {\"site\": 904, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02952236391821554, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.0856596731392245, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.022648736522369428, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08606876689907686, \"functional effect\": -1.4382, \"times_seen\": 8.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.01790197725057315, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08635241697469194, \"functional effect\": -2.1475, \"times_seen\": 8.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.028455248860702928, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08917218603595081, \"functional effect\": -1.2561, \"times_seen\": 1.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0308235868838734, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08931869192463458, \"functional effect\": 0.2966, \"times_seen\": 6.0}, {\"site\": 905, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.016688964372934736, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.0884478761372734, \"functional effect\": -2.625, \"times_seen\": 2.0}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.021861414590044075, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.08876555473223802, \"functional effect\": -2.6475, \"times_seen\": 1.0}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.012173086689148297, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.08669600107181821, \"functional effect\": -2.758, \"times_seen\": 1.0}, {\"site\": 906, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.22283793445558603, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.07491738804479277, \"functional effect\": -0.2602, \"times_seen\": 39.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.004625291334411516, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08715075995891225, \"functional effect\": -1.9937, \"times_seen\": 1.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015631481119015033, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08648842436694057, \"functional effect\": -1.4367, \"times_seen\": 20.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03959406200612525, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08986333463216516, \"functional effect\": -1.4034, \"times_seen\": 2.0}, {\"site\": 907, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004694422433915756, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08714658396652217, \"functional effect\": -1.2281, \"times_seen\": 1.0}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 2.639530630251117, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.544805425813241, \"functional effect\": -0.9528, \"times_seen\": 13.0}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.024951070975158977, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.08895585755813926, \"functional effect\": -1.7645, \"times_seen\": 10.0}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.10065212426156205, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.09374817854891535, \"functional effect\": -2.6745, \"times_seen\": 1.0}, {\"site\": 908, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.052039178537984634, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.09064187562054872, \"functional effect\": -1.8363, \"times_seen\": 18.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.014944154267635868, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.08652963888387802, \"functional effect\": -2.7658, \"times_seen\": 5.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.7416365118635884, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.026144401137393383, \"functional effect\": -1.7886, \"times_seen\": 3.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.03398440973345688, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.08539514951311639, \"functional effect\": -2.2041, \"times_seen\": 4.0}, {\"site\": 909, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.08047975726020232, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.09244647390450984, \"functional effect\": -0.0022, \"times_seen\": 13.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.012009550307898048, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.08670582903509659, \"functional effect\": -2.2618, \"times_seen\": 3.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.04434405349500636, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.0901596921603926, \"functional effect\": -2.4255, \"times_seen\": 3.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004558143922298999, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.08715481631456251, \"functional effect\": -2.311, \"times_seen\": 10.0}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 910, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.020713656682791466, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.08618428797399941, \"functional effect\": -2.3632, \"times_seen\": 3.0}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.027208153731061283, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.08909513707886475, \"functional effect\": -2.6387, \"times_seen\": 2.0}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01152205626506396, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.08673513232936451, \"functional effect\": -1.9719, \"times_seen\": 5.0}, {\"site\": 911, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009150887712310303, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.08687780470027398, \"functional effect\": -2.6153, \"times_seen\": 2.0}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004207555856151718, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.08717599830421871, \"functional effect\": -0.4727, \"times_seen\": 26.0}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0009908192729733713, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.08737058903352588, \"functional effect\": -2.1996, \"times_seen\": 1.0}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01646600423948185, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.08643840983400886, \"functional effect\": -2.468, \"times_seen\": 2.0}, {\"site\": 912, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 913, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0361324905858766, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": 0.08526809619547082, \"functional effect\": -1.7646, \"times_seen\": 29.0}, {\"site\": 913, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 914, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.061126034862535025, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": 0.083803616340417, \"functional effect\": -0.1498, \"times_seen\": 7.0}, {\"site\": 914, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.029422860142573438, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": 0.08566558135585906, \"functional effect\": -2.4585, \"times_seen\": 3.0}, {\"site\": 914, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0004658813523176292, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08740238541397387, \"functional effect\": -2.393, \"times_seen\": 2.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.06540181446436943, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09148532555762652, \"functional effect\": -0.5814, \"times_seen\": 4.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.00040376429714765965, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08740614871496584, \"functional effect\": -2.073, \"times_seen\": 7.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.05678198603611585, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09094034783085102, \"functional effect\": -1.6992, \"times_seen\": 10.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.13508660917908819, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09601269304868978, \"functional effect\": -1.4865, \"times_seen\": 29.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.06957852662454284, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09175056631243574, \"functional effect\": 0.4295, \"times_seen\": 5.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0009366494712357134, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08748739585716764, \"functional effect\": -1.0897, \"times_seen\": 1.0}, {\"site\": 915, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.013313172166981151, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08662751687734302, \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 916, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 916, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.001776948655636805, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": 0.08732299347421439, \"functional effect\": -2.0356, \"times_seen\": 1.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02703435457036591, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.0858075255527187, \"functional effect\": -2.9199, \"times_seen\": 4.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.3795154059345427, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.03360377075549699, \"functional effect\": -1.2457, \"times_seen\": 23.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.013906359600920834, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.08659190589215857, \"functional effect\": -3.1032, \"times_seen\": 1.0}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 917, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.014318580784282654, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.0865671675255442, \"functional effect\": -2.7045, \"times_seen\": 1.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.046001901811976935, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.08468677169787674, \"functional effect\": 0.1925, \"times_seen\": 9.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.033034512095381344, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.0894556774523685, \"functional effect\": 0.25, \"times_seen\": 11.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.05472790751303541, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.09081096102822753, \"functional effect\": -0.1995, \"times_seen\": 11.0}, {\"site\": 918, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.06966226005418294, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.08330922610085878, \"functional effect\": 0.2591, \"times_seen\": 8.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.03941681365363113, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.0850742025160728, \"functional effect\": -0.1284, \"times_seen\": 18.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03982690614245264, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.08505002323192101, \"functional effect\": -1.1435, \"times_seen\": 5.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03308052687362479, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.08544866837513139, \"functional effect\": 0.2593, \"times_seen\": 20.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.2544652406188523, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.03664644610171242, \"functional effect\": 0.3547, \"times_seen\": 13.0}, {\"site\": 919, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.23306622436028426, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.10275984830151876, \"functional effect\": -0.7893, \"times_seen\": 14.0}, {\"site\": 920, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 920, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010197472254866977, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": 0.08681480317000281, \"functional effect\": -2.1225, \"times_seen\": 3.0}, {\"site\": 920, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.004995505071856487, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": 0.08773387808654944, \"functional effect\": 0.3428, \"times_seen\": 8.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04433480324665252, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08478468760776305, \"functional effect\": -1.8836, \"times_seen\": 5.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.033473744050293255, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08542538188377721, \"functional effect\": -1.6701, \"times_seen\": 1.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.030891567021322393, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08557841559753171, \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.029145618945864524, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08568204520287724, \"functional effect\": -0.5601, \"times_seen\": 19.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.7642140144926366, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.05147687667357808, \"functional effect\": -2.3407, \"times_seen\": 18.0}, {\"site\": 921, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -4.299029156575718, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.0044414707015103085, \"functional effect\": -2.117, \"times_seen\": 23.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.00015866432643934158, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08744023027906782, \"functional effect\": -0.5035, \"times_seen\": 7.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.010532901659579354, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08679462090560966, \"functional effect\": -0.1584, \"times_seen\": 20.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.11146433303026546, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.09445340913286718, \"functional effect\": -1.4171, \"times_seen\": 10.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.021676596661416466, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08612678267737496, \"functional effect\": -0.7135, \"times_seen\": 14.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010123639387702462, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08804628761355, \"functional effect\": -0.7559, \"times_seen\": 5.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0351442818869089, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08958659143359059, \"functional effect\": -0.5794, \"times_seen\": 11.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.05352305135759226, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.09073515258168588, \"functional effect\": -0.8221, \"times_seen\": 10.0}, {\"site\": 922, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -1.2580705474686182, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.03655498066359007, \"functional effect\": -0.2915, \"times_seen\": 20.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.027170733303819698, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08579941450483394, \"functional effect\": -1.3777, \"times_seen\": 6.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.005710443312793574, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08708523241582172, \"functional effect\": -1.2896, \"times_seen\": 15.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07513697748393548, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.0829936845881408, \"functional effect\": -0.1869, \"times_seen\": 16.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.011272485701759155, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08811642852021212, \"functional effect\": -2.9703, \"times_seen\": 3.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0053279308049469665, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08710832503492431, \"functional effect\": -2.9053, \"times_seen\": 1.0}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 923, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.013940210163458217, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08827951761146761, \"functional effect\": -2.3285, \"times_seen\": 8.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008730691377409667, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.08690311223297674, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.014522712845812302, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.0865549196950949, \"functional effect\": -2.2115, \"times_seen\": 4.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02487373155776875, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.08593612973239738, \"functional effect\": -2.0167, \"times_seen\": 5.0}, {\"site\": 924, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.009321964591833659, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.08799737576445123, \"functional effect\": -2.7049, \"times_seen\": 1.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008146934419026983, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08693828291001135, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.028111844758362696, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08915096294344786, \"functional effect\": -2.5455, \"times_seen\": 2.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004583941880919871, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08715325784504648, \"functional effect\": -2.717, \"times_seen\": 1.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.006629607041525504, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08702976671382695, \"functional effect\": -2.2128, \"times_seen\": 3.0}, {\"site\": 925, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.009376420206288845, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08686422439676535, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.005898212677790812, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08707389885310964, \"functional effect\": 0.2868, \"times_seen\": 1.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.3333633732677136, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.1101579650951357, \"functional effect\": -0.488, \"times_seen\": 3.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.026102334081090264, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08902687219864917, \"functional effect\": 0.2219, \"times_seen\": 4.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.43359193073864255, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.11808308938561558, \"functional effect\": -0.0993, \"times_seen\": 28.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -1.1894678672462151, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.03833522556923627, \"functional effect\": -0.1288, \"times_seen\": 20.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.024633473967828376, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08893627684021789, \"functional effect\": -2.9645, \"times_seen\": 1.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.018190320309572405, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08633515994441075, \"functional effect\": -0.2751, \"times_seen\": 7.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.014279212970415948, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08656952977573543, \"functional effect\": 0.1001, \"times_seen\": 30.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.13011707761272612, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.07989036156035141, \"functional effect\": -0.4408, \"times_seen\": 14.0}, {\"site\": 926, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.027384248452752058, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08910601265580208, \"functional effect\": -0.4279, \"times_seen\": 8.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.00884392896732364, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08689629144790664, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.010987603605222784, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08676726968915262, \"functional effect\": -0.7905, \"times_seen\": 4.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0037606415394667125, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08720300764141556, \"functional effect\": -2.3045, \"times_seen\": 1.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01328294266467624, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08662933204554046, \"functional effect\": -0.575, \"times_seen\": 11.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010914918655157094, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08677164125303692, \"functional effect\": -1.8084, \"times_seen\": 3.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03611266012201965, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08526926825018301, \"functional effect\": -0.4934, \"times_seen\": 7.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0025567907210655213, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08727580419310513, \"functional effect\": -2.9182, \"times_seen\": 1.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.035708565534092886, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08529315526366874, \"functional effect\": -1.9236, \"times_seen\": 4.0}, {\"site\": 927, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.012778648526304757, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08665961862680055, \"functional effect\": -2.7247, \"times_seen\": 3.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008884345978589796, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08689385708784031, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.014807468608354362, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08653783737399698, \"functional effect\": -0.4695, \"times_seen\": 2.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.00061144522612368, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08746767716035518, \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.024624273133147995, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08595099035396578, \"functional effect\": -0.3694, \"times_seen\": 5.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005516830723879412, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08709692021418067, \"functional effect\": -2.4165, \"times_seen\": 1.0}, {\"site\": 928, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03143947840731123, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.085545920521166, \"functional effect\": -0.6782, \"times_seen\": 8.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008761876575062772, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08690123376152956, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.00454000101617331, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08715591235464627, \"functional effect\": -0.1662, \"times_seen\": 7.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.010993524481416588, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08809939187048592, \"functional effect\": -0.0122, \"times_seen\": 14.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.023938149590696248, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08889342325039012, \"functional effect\": 0.3633, \"times_seen\": 79.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.003261938041043887, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08723315674503733, \"functional effect\": 0.1018, \"times_seen\": 8.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0048329427238863855, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08713821699343927, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00434335872188362, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08716779269397136, \"functional effect\": 0.0408, \"times_seen\": 26.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.08692916975716422, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.09286067101201195, \"functional effect\": -0.1759, \"times_seen\": 41.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.4147138449852383, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.06558767303956001, \"functional effect\": 0.2646, \"times_seen\": 18.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -8.57744593462399e-05, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08742541635615778, \"functional effect\": 0.1853, \"times_seen\": 27.0}, {\"site\": 929, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.10423573265596603, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.09398133548693717, \"functional effect\": 0.2353, \"times_seen\": 15.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.00847511531735326, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.0869185086416565, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.07373911152851603, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.09201554746481687, \"functional effect\": 0.2416, \"times_seen\": 21.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004484309440011676, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08715927685211784, \"functional effect\": 0.2802, \"times_seen\": 2.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0003933582869295217, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08745445599043974, \"functional effect\": -0.2066, \"times_seen\": 4.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.008311864819617423, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.0869283446029953, \"functional effect\": 0.3491, \"times_seen\": 11.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06106564846198242, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08380712415358058, \"functional effect\": 0.0968, \"times_seen\": 16.0}, {\"site\": 930, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.027742339872972626, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08576542686839579, \"functional effect\": 0.2991, \"times_seen\": 11.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.006139464311035462, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08780347268486137, \"functional effect\": -0.1736, \"times_seen\": 6.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.02645054167212899, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.0890483622385913, \"functional effect\": 0.1345, \"times_seen\": 9.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0079414450496631, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08791321106665244, \"functional effect\": -0.5846, \"times_seen\": 24.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004898021313523841, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08713428636069724, \"functional effect\": -1.3962, \"times_seen\": 8.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.022592026298240784, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08607215020244749, \"functional effect\": 0.0468, \"times_seen\": 8.0}, {\"site\": 931, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.021222138777415713, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08615391742157061, \"functional effect\": 0.1355, \"times_seen\": 22.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.012668818555434499, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08820175454044198, \"functional effect\": -0.131, \"times_seen\": 8.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03765649953185271, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08517806973451866, \"functional effect\": 0.3085, \"times_seen\": 33.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.139831440845618, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.19265797166831464, \"functional effect\": 0.1257, \"times_seen\": 32.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03470186305375701, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08535269299924897, \"functional effect\": -0.6738, \"times_seen\": 12.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.026648852710924306, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08906060355535218, \"functional effect\": -0.1322, \"times_seen\": 2.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.07165337906007962, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08319432713490384, \"functional effect\": -0.061, \"times_seen\": 66.0}, {\"site\": 932, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.012219101893465862, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08669323592016112, \"functional effect\": 0.1988, \"times_seen\": 9.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0008262907401599613, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08738055356111227, \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.24168450791899276, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.07394507326719267, \"functional effect\": -0.1452, \"times_seen\": 116.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -2.9814404702089856, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.011070328751199666, \"functional effect\": -0.341, \"times_seen\": 33.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.08660489612720684, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.09283980112467459, \"functional effect\": 0.0714, \"times_seen\": 117.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.03222822601822141, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08549916379350456, \"functional effect\": -0.3468, \"times_seen\": 31.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.042721721159007194, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08487953866361467, \"functional effect\": -0.6219, \"times_seen\": 142.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.10527949911899018, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08127766956395707, \"functional effect\": 0.01, \"times_seen\": 58.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.007389542868668895, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08787958634889721, \"functional effect\": 0.0112, \"times_seen\": 26.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.6022124185404085, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.057594303180337446, \"functional effect\": -0.1797, \"times_seen\": 42.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.22291253906820416, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.07491351401872094, \"functional effect\": 0.0491, \"times_seen\": 98.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.938931085690582, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.16761386887704743, \"functional effect\": 0.1434, \"times_seen\": 45.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07950524923478502, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08274277178023452, \"functional effect\": -0.1217, \"times_seen\": 91.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.009105580988089976, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08688053307351529, \"functional effect\": -1.156, \"times_seen\": 43.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.1243842342620339, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.09530307541165338, \"functional effect\": -0.0172, \"times_seen\": 49.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.5451314430754955, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.059918731967779304, \"functional effect\": 0.0486, \"times_seen\": 120.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.6130738966973435, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.057162326669049315, \"functional effect\": -0.1925, \"times_seen\": 109.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -3.2832876931998163, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.008980395217402997, \"functional effect\": 0.0011, \"times_seen\": 93.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.2738521767942657, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.10570639198429396, \"functional effect\": -0.0316, \"times_seen\": 120.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.09914486709074777, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08162401454841749, \"functional effect\": -0.2886, \"times_seen\": 56.0}, {\"site\": 933, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0692753197912744, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.09173128540086446, \"functional effect\": -0.1037, \"times_seen\": 108.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.017515137659620653, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08637557433754797, \"functional effect\": -0.3931, \"times_seen\": 11.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0035303397398301255, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08721692923403601, \"functional effect\": -0.2537, \"times_seen\": 3.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.019165219220275222, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08627683880294283, \"functional effect\": 0.1902, \"times_seen\": 13.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01041732568238743, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08680157440213183, \"functional effect\": -0.0403, \"times_seen\": 3.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0028397899445628547, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.0872586858404406, \"functional effect\": 0.3646, \"times_seen\": 19.0}, {\"site\": 934, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018392689085109572, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.086323050444629, \"functional effect\": 0.085, \"times_seen\": 4.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.009121428725345838, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08798514490269192, \"functional effect\": -0.2643, \"times_seen\": 16.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.029153405400999838, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08568158276446747, \"functional effect\": -0.4609, \"times_seen\": 19.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.5320661618226765, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.06046383028716602, \"functional effect\": -0.4381, \"times_seen\": 7.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.09812296358229372, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.0816818517302175, \"functional effect\": -2.0938, \"times_seen\": 1.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00806823317472239, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.0869430256570765, \"functional effect\": -2.6479, \"times_seen\": 1.0}, {\"site\": 935, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.006068744992869173, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08706360697882738, \"functional effect\": -1.144, \"times_seen\": 6.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": 3.419530806324845, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.9355023305473861, \"functional effect\": -2.8311, \"times_seen\": 10.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.09924278954592237, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08161847453307797, \"functional effect\": 0.1087, \"times_seen\": 165.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.07674789119153724, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09220764863286122, \"functional effect\": -0.6542, \"times_seen\": 61.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.06785158024405367, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09164080402157791, \"functional effect\": -0.4094, \"times_seen\": 72.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.08998225936890908, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08214406124907285, \"functional effect\": 0.0374, \"times_seen\": 62.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.030002617932454973, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08563116291754648, \"functional effect\": -1.7198, \"times_seen\": 99.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.26345700251216125, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0728375064637214, \"functional effect\": -0.0382, \"times_seen\": 62.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.05814007139507847, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08397724532312867, \"functional effect\": -0.4664, \"times_seen\": 49.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.3181287207807042, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.035064467411852485, \"functional effect\": -0.3065, \"times_seen\": 47.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.020037797326063072, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0886534228338818, \"functional effect\": -0.2325, \"times_seen\": 27.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.25364845221065035, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.10423638047348055, \"functional effect\": -0.6924, \"times_seen\": 140.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.046267944651506555, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0846711563174043, \"functional effect\": -0.2322, \"times_seen\": 26.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.12070704164565284, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0950604728396439, \"functional effect\": 0.309, \"times_seen\": 69.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01601198382565987, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08646561653907563, \"functional effect\": -1.9366, \"times_seen\": 51.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010003656427473329, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08803896547362884, \"functional effect\": 0.0502, \"times_seen\": 36.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3151735525384728, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.07027273181113566, \"functional effect\": -0.2679, \"times_seen\": 76.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.07612911276182571, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0829366298026786, \"functional effect\": -0.5069, \"times_seen\": 140.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.042658505656660115, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09005441715104288, \"functional effect\": -0.5598, \"times_seen\": 83.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.04905393342978388, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09045451207618624, \"functional effect\": -1.3738, \"times_seen\": 21.0}, {\"site\": 936, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -1.9963845180763349, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.02191249889200429, \"functional effect\": -0.7689, \"times_seen\": 137.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.03629149229072997, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08965785773736674, \"functional effect\": -0.3529, \"times_seen\": 33.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.03632923113938931, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.0896602030899767, \"functional effect\": -0.5469, \"times_seen\": 40.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.011919056402826955, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.0867112678804021, \"functional effect\": -0.1498, \"times_seen\": 9.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.016223574464442003, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08841934889533154, \"functional effect\": -0.7398, \"times_seen\": 4.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.13744899035022706, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.07948538112799393, \"functional effect\": -0.0335, \"times_seen\": 57.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.04506969688010264, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08474151018036756, \"functional effect\": 0.0747, \"times_seen\": 21.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02184059499120092, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08611699277352879, \"functional effect\": -0.1382, \"times_seen\": 7.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.011716287337020048, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08672345590207862, \"functional effect\": 0.0508, \"times_seen\": 32.0}, {\"site\": 937, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01245438303836124, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08667909875321017, \"functional effect\": -0.64, \"times_seen\": 20.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0520092606396731, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08433487051345293, \"functional effect\": -0.4902, \"times_seen\": 24.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.003653872059864003, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.0872094615100542, \"functional effect\": -0.3262, \"times_seen\": 14.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 1.5687701148944297, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.25936441533018145, \"functional effect\": -1.7567, \"times_seen\": 19.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.010669382008287272, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08678641043874111, \"functional effect\": -2.3738, \"times_seen\": 20.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.13439185409907312, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.0796539928419426, \"functional effect\": 0.0207, \"times_seen\": 41.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.055633357756589875, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08412328442793249, \"functional effect\": 0.1825, \"times_seen\": 21.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.09418832732419545, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08190492523042735, \"functional effect\": 0.2632, \"times_seen\": 63.0}, {\"site\": 938, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.2373392191559476, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.03708406299842734, \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.010753316828288657, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08808472460823003, \"functional effect\": 0.3737, \"times_seen\": 9.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06912801867606777, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08334008187855821, \"functional effect\": -0.0503, \"times_seen\": 23.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.09530953840276099, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.0818412963749544, \"functional effect\": 0.1371, \"times_seen\": 73.0}, {\"site\": 939, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.04588146258356954, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08469384182351301, \"functional effect\": 0.0072, \"times_seen\": 28.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.03438769370130622, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.0853712819036643, \"functional effect\": -2.1849, \"times_seen\": 4.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.833197983535168, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.04907337694005678, \"functional effect\": -0.1717, \"times_seen\": 54.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.19041771042910927, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.07661998937401869, \"functional effect\": 0.0675, \"times_seen\": 45.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.5331225403999854, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.06041957331372693, \"functional effect\": 0.3598, \"times_seen\": 41.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0378841141807689, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08516463221199322, \"functional effect\": 0.0001, \"times_seen\": 11.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.12526202432010075, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08015966680568651, \"functional effect\": 0.2112, \"times_seen\": 46.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.40768260298253867, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.11598136672487754, \"functional effect\": 0.1457, \"times_seen\": 72.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.011370809247536879, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08674422580884328, \"functional effect\": 0.0644, \"times_seen\": 24.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.030283007509588098, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08928523038470382, \"functional effect\": -0.2432, \"times_seen\": 31.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.10609650325282596, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.09410262968068148, \"functional effect\": 0.2043, \"times_seen\": 20.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.09163364330029825, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08205008866875889, \"functional effect\": -0.1505, \"times_seen\": 68.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.01860396307207349, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08631040988014818, \"functional effect\": 0.1411, \"times_seen\": 28.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.045226858541560756, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.09021487900591918, \"functional effect\": 0.3343, \"times_seen\": 42.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.11188679178468845, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08090628304872705, \"functional effect\": 0.4107, \"times_seen\": 73.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.006556547124890528, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08703417412379358, \"functional effect\": 0.1028, \"times_seen\": 3.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.06462221762589088, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08360077511448336, \"functional effect\": -0.2136, \"times_seen\": 59.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07818451507214214, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.0922995139843536, \"functional effect\": 0.1314, \"times_seen\": 36.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.2206766192377383, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.07502970661100183, \"functional effect\": -0.2812, \"times_seen\": 64.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.006531153932922478, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.0878273144373549, \"functional effect\": 0.363, \"times_seen\": 7.0}, {\"site\": 940, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.12028290725674311, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.09503253035114892, \"functional effect\": 0.2419, \"times_seen\": 46.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.012657866295992573, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08666687406185562, \"functional effect\": -0.1909, \"times_seen\": 6.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.012157865659037786, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08817052204775616, \"functional effect\": -1.4308, \"times_seen\": 5.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.008501040390599698, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08691694673952689, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.022216709937998378, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08878741789218596, \"functional effect\": 0.3315, \"times_seen\": 20.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0690596632985201, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08334403065328823, \"functional effect\": 0.25, \"times_seen\": 24.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.14939631396118558, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.07882986053573308, \"functional effect\": 0.1042, \"times_seen\": 23.0}, {\"site\": 941, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.032094027372123135, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08939738080675858, \"functional effect\": -0.2985, \"times_seen\": 1.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.016169362045225424, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08841602640747881, \"functional effect\": -0.2514, \"times_seen\": 9.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.02793279414589431, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08913989924421606, \"functional effect\": -1.0993, \"times_seen\": 8.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0017020937051521366, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08753382596821661, \"functional effect\": -0.5101, \"times_seen\": 4.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03839228856691957, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.0897885091161976, \"functional effect\": -0.0568, \"times_seen\": 4.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.027578435398905338, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08911800714427781, \"functional effect\": -2.7921, \"times_seen\": 17.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004678211166250698, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08714756322027725, \"functional effect\": -1.8188, \"times_seen\": 1.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.000442449937680661, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08740380496426402, \"functional effect\": -2.9466, \"times_seen\": 1.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.013781202547240176, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08659941826144874, \"functional effect\": -1.3313, \"times_seen\": 11.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0023700653954855135, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08728710086853289, \"functional effect\": -0.1611, \"times_seen\": 6.0}, {\"site\": 942, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0014355121338346622, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.0873436622827456, \"functional effect\": -0.1081, \"times_seen\": 1.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.006069649814486649, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08779922382647491, \"functional effect\": -0.3291, \"times_seen\": 14.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.8535704847305545, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.15798427055172679, \"functional effect\": 0.1577, \"times_seen\": 4.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02270360111823821, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08606549383152573, \"functional effect\": 0.2621, \"times_seen\": 77.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.009805345477664283, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08683840277686695, \"functional effect\": 0.3216, \"times_seen\": 10.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.024495524710046252, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08892777323655249, \"functional effect\": -0.0948, \"times_seen\": 21.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.7094742528572479, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.1429672492418784, \"functional effect\": 0.2133, \"times_seen\": 5.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.016609851885342745, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08844302608965161, \"functional effect\": -0.4021, \"times_seen\": 2.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011322722838579751, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08674711712524405, \"functional effect\": -0.25, \"times_seen\": 21.0}, {\"site\": 943, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.09357756815494866, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.0932895901087398, \"functional effect\": -0.7046, \"times_seen\": 7.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.02092904159306384, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08617142218530308, \"functional effect\": -0.3957, \"times_seen\": 12.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.004071854919960489, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08767772659743198, \"functional effect\": -1.64, \"times_seen\": 1.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02098166679682803, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08871144246756332, \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.02017802073633309, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08866203996299182, \"functional effect\": -0.2645, \"times_seen\": 10.0}, {\"site\": 944, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.9520006246338881, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.16913920068060917, \"functional effect\": 0.3292, \"times_seen\": 4.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.018507957261648444, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.08631615369733106, \"functional effect\": -2.9634, \"times_seen\": 5.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004156394875271884, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.08717908980210119, \"functional effect\": -2.0743, \"times_seen\": 1.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.07541067244058491, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.09212222193676357, \"functional effect\": -0.1733, \"times_seen\": 27.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.009189597454871114, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.08687547366548021, \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 945, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0043858527781016, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.08716522523624326, \"functional effect\": -3.126, \"times_seen\": 1.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0027207982653910047, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.0872658831243147, \"functional effect\": 0.096, \"times_seen\": 4.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.033961160435193725, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.08539652568288368, \"functional effect\": -0.6883, \"times_seen\": 15.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.011113650079906995, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.08675968927166804, \"functional effect\": -1.4144, \"times_seen\": 2.0}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 946, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3018328804712776, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.07092556094145214, \"functional effect\": -1.6677, \"times_seen\": 18.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.007935777404528882, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08695100837953045, \"functional effect\": -2.9788, \"times_seen\": 3.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.13981762619121482, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.0793549880455186, \"functional effect\": -0.3039, \"times_seen\": 49.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00582291836633877, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08707844336193521, \"functional effect\": -1.4446, \"times_seen\": 10.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.24336638383974388, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.07385891924960561, \"functional effect\": -0.2797, \"times_seen\": 66.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.07602803194576165, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08294244086854814, \"functional effect\": -1.3733, \"times_seen\": 19.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.11288769773414274, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.09454664296737299, \"functional effect\": -0.6903, \"times_seen\": 71.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -2.500789112470893, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.015447243562255046, \"functional effect\": -0.6543, \"times_seen\": 18.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.014662369045021743, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08654654138525532, \"functional effect\": -1.0843, \"times_seen\": 26.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.412275562056615, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.03284930788266076, \"functional effect\": -0.4556, \"times_seen\": 23.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.3400293879449501, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.11066813090858317, \"functional effect\": -0.9281, \"times_seen\": 29.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05188211033534828, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08434230359993324, \"functional effect\": -0.2803, \"times_seen\": 12.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.026729574618174597, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08582565493934154, \"functional effect\": -0.1851, \"times_seen\": 47.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.020843339213241784, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08870293710028031, \"functional effect\": -2.5739, \"times_seen\": 3.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.10530290869191843, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.09405088014456474, \"functional effect\": -0.3614, \"times_seen\": 24.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -2.246583673459801, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.01842359832491817, \"functional effect\": -0.5694, \"times_seen\": 43.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.762396405091182, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.14830907167204144, \"functional effect\": -0.507, \"times_seen\": 63.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.012319123235521411, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08668722572883104, \"functional effect\": -0.3584, \"times_seen\": 23.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.005049581137354426, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08773716664838614, \"functional effect\": -0.9083, \"times_seen\": 32.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.07684403405256063, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08289554109582169, \"functional effect\": -1.3042, \"times_seen\": 22.0}, {\"site\": 947, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.007367460578014406, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08787824124985556, \"functional effect\": -1.1047, \"times_seen\": 20.0}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.004931121243345445, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.08713228725097791, \"functional effect\": -1.763, \"times_seen\": 1.0}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.003993588681393352, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.08718892840019121, \"functional effect\": -1.4484, \"times_seen\": 3.0}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.006569201752038146, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.08782963071469897, \"functional effect\": -1.2045, \"times_seen\": 17.0}, {\"site\": 948, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.007804916063418616, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08790489182154085, \"functional effect\": -1.0805, \"times_seen\": 6.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.016016652114952113, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08840666802592653, \"functional effect\": -2.3314, \"times_seen\": 3.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.013749535477325969, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08660131913436526, \"functional effect\": -1.4429, \"times_seen\": 18.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01663492816313676, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08642828942732293, \"functional effect\": -1.7319, \"times_seen\": 3.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.2218886869090555, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.07496669752854683, \"functional effect\": -0.0287, \"times_seen\": 24.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01634516357251723, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08644565025021735, \"functional effect\": -1.4796, \"times_seen\": 5.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.027743496800019096, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08576535809135047, \"functional effect\": -1.1134, \"times_seen\": 8.0}, {\"site\": 949, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.009077665301172027, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.08688221420026532, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004145199990672997, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.08717976628854407, \"functional effect\": -0.9502, \"times_seen\": 6.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.04782622147488004, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.09037756937917028, \"functional effect\": -0.8839, \"times_seen\": 3.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03700688244936314, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.08521643237330374, \"functional effect\": -0.5432, \"times_seen\": 24.0}, {\"site\": 950, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.7449778408303961, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.14652920932657984, \"functional effect\": -0.1638, \"times_seen\": 18.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.03702994617825103, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08521507006669883, \"functional effect\": -2.3194, \"times_seen\": 8.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004950433139452696, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08713112090717752, \"functional effect\": -0.8217, \"times_seen\": 1.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.4300123296658228, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.0648958492635359, \"functional effect\": 0.354, \"times_seen\": 80.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.6062930733997095, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.057431628186821695, \"functional effect\": -0.3075, \"times_seen\": 63.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.057431845106834904, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08401848029775455, \"functional effect\": 0.054, \"times_seen\": 79.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.7228645942354989, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.14430037364254264, \"functional effect\": 0.1434, \"times_seen\": 34.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.18771247101985636, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.07676379652973278, \"functional effect\": 0.0385, \"times_seen\": 58.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.04332792059964757, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.09009621237380686, \"functional effect\": -0.1723, \"times_seen\": 66.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.577896604157554, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.13050517765956457, \"functional effect\": 0.2681, \"times_seen\": 37.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.013001751117703098, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08822211131986549, \"functional effect\": 0.2298, \"times_seen\": 59.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.00034168161793385625, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08740991009522683, \"functional effect\": 0.1357, \"times_seen\": 179.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.09019479835861959, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08213196061149276, \"functional effect\": 0.3673, \"times_seen\": 35.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.12354346564876066, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08025521102636295, \"functional effect\": 0.1962, \"times_seen\": 63.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.028630036362704708, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08918299020966852, \"functional effect\": -2.4186, \"times_seen\": 16.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09731394397366645, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.09353151006797547, \"functional effect\": 0.3579, \"times_seen\": 114.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.008033889769819925, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.0869450953634172, \"functional effect\": 0.2391, \"times_seen\": 181.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.3444445362480665, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.11100733263003852, \"functional effect\": 0.157, \"times_seen\": 161.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.011777704202730735, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08814729148465109, \"functional effect\": 0.3262, \"times_seen\": 66.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.5443093003692892, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.05995288734089545, \"functional effect\": 0.3553, \"times_seen\": 113.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.02777381272075139, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08576355588894041, \"functional effect\": 0.1018, \"times_seen\": 29.0}, {\"site\": 951, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06071553580054143, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.0838274649013381, \"functional effect\": 0.0851, \"times_seen\": 67.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.01451212526136183, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08655555490271576, \"functional effect\": -2.0274, \"times_seen\": 13.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.06145410629405823, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08378456141488272, \"functional effect\": -1.5595, \"times_seen\": 9.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.004854590005231026, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08772530910893, \"functional effect\": -0.2737, \"times_seen\": 12.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06179168123761, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08376495903251983, \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 952, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0009054253134888267, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08748550239346903, \"functional effect\": -0.1368, \"times_seen\": 1.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.012795843924420066, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08665858574201192, \"functional effect\": -1.2581, \"times_seen\": 5.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02468911664795922, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.0859471272790196, \"functional effect\": -0.3312, \"times_seen\": 8.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.005067888092818597, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08773827998873027, \"functional effect\": -0.1056, \"times_seen\": 10.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.027009953018740863, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08580897690204256, \"functional effect\": -0.9177, \"times_seen\": 9.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.006902645065467779, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08784993270985703, \"functional effect\": -0.1719, \"times_seen\": 16.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.021489303670303616, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08613796452066348, \"functional effect\": -0.122, \"times_seen\": 17.0}, {\"site\": 953, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.019819665258955548, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.0862377101381754, \"functional effect\": 0.3986, \"times_seen\": 8.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.12916698299250912, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.09561954356721139, \"functional effect\": -0.0619, \"times_seen\": 32.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0653618210526258, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.08355792782406844, \"functional effect\": -0.0952, \"times_seen\": 27.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.025011790538039303, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.08895960157492742, \"functional effect\": -0.5593, \"times_seen\": 17.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.15656666900008895, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.09745290589848654, \"functional effect\": -0.2516, \"times_seen\": 77.0}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 954, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.05835408061515065, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.09103949889677847, \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004364708696683556, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08716650273569583, \"functional effect\": -0.3862, \"times_seen\": 1.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.098592090825864, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.09361441045467973, \"functional effect\": -0.9988, \"times_seen\": 9.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.026959682781226887, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08907979381748507, \"functional effect\": -1.2735, \"times_seen\": 3.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.009084830192922031, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08798291290892798, \"functional effect\": -0.54, \"times_seen\": 39.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.013859602893851068, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08827458533410845, \"functional effect\": -1.6606, \"times_seen\": 13.0}, {\"site\": 955, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.018929754794406357, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08629092132465396, \"functional effect\": -2.7862, \"times_seen\": 5.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.3164722976799932, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.03510474962534765, \"functional effect\": -0.2794, \"times_seen\": 2.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01234732874759766, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08668553096062163, \"functional effect\": -2.7605, \"times_seen\": 2.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012816893984070972, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08665732133405357, \"functional effect\": -1.3264, \"times_seen\": 1.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.016395601881484825, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08644262806183022, \"functional effect\": -0.2295, \"times_seen\": 1.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.010898564874079253, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08677262486525397, \"functional effect\": -1.2439, \"times_seen\": 1.0}, {\"site\": 956, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.09450732440187379, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08188681707678083, \"functional effect\": -2.1038, \"times_seen\": 6.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"A\", \"log2 fold change IC90\": -1.5349262620786346, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.030172040635143883, \"functional effect\": 0.1938, \"times_seen\": 9.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.038217008480715735, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08514498318765534, \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004769539854321818, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08714204658614752, \"functional effect\": -0.9805, \"times_seen\": 1.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.034765063669911944, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08534895400765269, \"functional effect\": -0.3297, \"times_seen\": 11.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.029089473399305153, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08568537976682301, \"functional effect\": -0.0866, \"times_seen\": 21.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.033926750785186296, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.0853985624955989, \"functional effect\": -0.2975, \"times_seen\": 11.0}, {\"site\": 957, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01131186220448744, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08674777016155259, \"functional effect\": -1.2786, \"times_seen\": 1.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.08013855755385052, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.08270645767061956, \"functional effect\": -0.4658, \"times_seen\": 43.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.09767108051843824, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.09355466648996195, \"functional effect\": -0.425, \"times_seen\": 4.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05276305130268774, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.0842908180757898, \"functional effect\": -0.2616, \"times_seen\": 24.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -2.1116135574078947, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.020230401868325927, \"functional effect\": 0.2815, \"times_seen\": 5.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.042971255240140026, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.08486485884183914, \"functional effect\": -0.9293, \"times_seen\": 10.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02416806889831969, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.08597817378840468, \"functional effect\": -0.2061, \"times_seen\": 27.0}, {\"site\": 958, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.002816821227273847, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08726007507100121, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.008130767548942725, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08693925714764335, \"functional effect\": -2.8737, \"times_seen\": 2.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.017630064198693538, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08850559133930314, \"functional effect\": -2.8218, \"times_seen\": 2.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.009821464085885377, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08683743257434039, \"functional effect\": -2.7538, \"times_seen\": 3.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.017006655315571995, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08846735508630775, \"functional effect\": -2.7581, \"times_seen\": 3.0}, {\"site\": 959, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004462498011198746, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08716059458225436, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004061335023135177, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08718483426242156, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.006986533319091141, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08700823800016949, \"functional effect\": -2.5528, \"times_seen\": 3.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.11086646762609043, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08096352302742038, \"functional effect\": -0.3528, \"times_seen\": 30.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.023284441222383562, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08885315333219199, \"functional effect\": -0.5852, \"times_seen\": 26.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.030819182930245926, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08558270941642898, \"functional effect\": -0.4396, \"times_seen\": 31.0}, {\"site\": 960, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0028273273725680703, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08725943961883495, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -6.782509376695385e-05, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.0874265040708005, \"functional effect\": -0.1421, \"times_seen\": 1.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.022157639173532678, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08609806993052559, \"functional effect\": -0.1207, \"times_seen\": 3.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.039006038409612115, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08509842894707907, \"functional effect\": -0.0698, \"times_seen\": 13.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.041039565139625575, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.0849785643724422, \"functional effect\": 0.0106, \"times_seen\": 11.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0006936835777295876, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08738858562573952, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.10794207741713116, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.09422308792779613, \"functional effect\": -0.0124, \"times_seen\": 20.0}, {\"site\": 961, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.05413319691980563, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.09077353446944383, \"functional effect\": -0.1502, \"times_seen\": 22.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0123337480625528, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.086686346971214, \"functional effect\": -2.4019, \"times_seen\": 2.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004097136376310688, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08718267074468156, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.10961326262044378, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08103388299318141, \"functional effect\": -0.4059, \"times_seen\": 30.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.023819265991935856, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.0859989633951091, \"functional effect\": -0.3547, \"times_seen\": 12.0}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 962, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004634744737463232, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.0871501888967421, \"functional effect\": -2.2174, \"times_seen\": 1.0}, {\"site\": 963, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.003030290993629679, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": 0.08724716450482614, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 963, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.003203047614528013, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.0872367176518904, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.027676437392138705, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.0857693447327661, \"functional effect\": -0.1633, \"times_seen\": 4.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0027352072052098286, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08726501155926224, \"functional effect\": -1.6437, \"times_seen\": 1.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.021191048056280595, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08615577409689555, \"functional effect\": -0.3437, \"times_seen\": 5.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.031802651636276526, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08552438854301607, \"functional effect\": -2.0275, \"times_seen\": 10.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.016291541956544444, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.0884235145594471, \"functional effect\": -1.1687, \"times_seen\": 4.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0030905675775611432, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08761811054045124, \"functional effect\": -0.681, \"times_seen\": 24.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.007954018984146959, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08694990896928104, \"functional effect\": -2.4424, \"times_seen\": 3.0}, {\"site\": 964, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005320349680848923, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08710878277598423, \"functional effect\": -2.1403, \"times_seen\": 1.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.007054177399965729, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08700415851410791, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.03592671902345431, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08963519137021334, \"functional effect\": -0.6781, \"times_seen\": 52.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -1.9487100027758728, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.022648704539014814, \"functional effect\": 0.3242, \"times_seen\": 8.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.02497197742693994, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08593027778028611, \"functional effect\": -1.0771, \"times_seen\": 10.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02576360589213153, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.0858831394785188, \"functional effect\": -0.0723, \"times_seen\": 4.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.02131118798615943, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08614859980336867, \"functional effect\": 0.3441, \"times_seen\": 23.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006740367471408071, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.0870230854096817, \"functional effect\": -2.4785, \"times_seen\": 3.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.027761062778352504, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08576431383514414, \"functional effect\": -1.1234, \"times_seen\": 5.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0857981223400559, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08238264313020115, \"functional effect\": -0.0446, \"times_seen\": 21.0}, {\"site\": 965, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.013802209038967669, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.0865981573319606, \"functional effect\": -0.0248, \"times_seen\": 19.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.03380190507508869, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0895032730408796, \"functional effect\": -2.7391, \"times_seen\": 2.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.004997889778207138, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08773402310660094, \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.03802066589617328, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08976538354396191, \"functional effect\": -1.6117, \"times_seen\": 17.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0029554652218257223, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0872516897201604, \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0545115335775646, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0841887232299473, \"functional effect\": -2.5324, \"times_seen\": 9.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009894343649656214, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08683304598245656, \"functional effect\": -2.4857, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.020886046180607052, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08617399031712755, \"functional effect\": -2.262, \"times_seen\": 12.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.022556681877580434, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08607425890003283, \"functional effect\": -2.3963, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.06289555680777457, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.09132653471953384, \"functional effect\": -2.8676, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005832676397402333, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08707785438695603, \"functional effect\": -2.2689, \"times_seen\": 10.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.016804192372269218, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0884549407479769, \"functional effect\": -2.9869, \"times_seen\": 4.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.17937302157738894, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0772088119947232, \"functional effect\": -1.4827, \"times_seen\": 55.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.49091606329611037, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.062213275816547606, \"functional effect\": -1.4039, \"times_seen\": 28.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.009176288005138877, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08798849065028037, \"functional effect\": -2.3216, \"times_seen\": 24.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.4182403690648591, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.06542754630360383, \"functional effect\": 0.1338, \"times_seen\": 167.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.20826606058418495, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.10100848592802324, \"functional effect\": -0.5279, \"times_seen\": 99.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07650366393341641, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.09219204054206533, \"functional effect\": 0.1531, \"times_seen\": 71.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.012527981584226182, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08819314463931484, \"functional effect\": -2.642, \"times_seen\": 5.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.008078023858149394, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08792153413538546, \"functional effect\": -2.8316, \"times_seen\": 6.0}, {\"site\": 966, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0058483019230813026, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08707691127018993, \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.015785020214044838, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.08647922030965358, \"functional effect\": -2.9828, \"times_seen\": 1.0}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.008411783626162444, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.08692232429002077, \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 967, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0008403982465316538, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.087379699107708, \"functional effect\": -0.7589, \"times_seen\": 1.0}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0084254751452605, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.08692149938040218, \"functional effect\": -3.0212, \"times_seen\": 1.0}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.018105771596526734, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.08634021973899968, \"functional effect\": -1.9913, \"times_seen\": 4.0}, {\"site\": 968, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.020619348734087713, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.0886891662959759, \"functional effect\": -2.7955, \"times_seen\": 5.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.05312830390894825, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.09071032919956967, \"functional effect\": -0.2237, \"times_seen\": 20.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.009175425741873978, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08798843806174406, \"functional effect\": -2.2134, \"times_seen\": 5.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0585368351565224, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08395415343914449, \"functional effect\": -2.0949, \"times_seen\": 17.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02382402500727897, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08599867971096264, \"functional effect\": -1.7998, \"times_seen\": 9.0}, {\"site\": 969, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01941581048031835, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.0862618541086281, \"functional effect\": -2.9983, \"times_seen\": 5.0}, {\"site\": 970, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.014931954003719295, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": 0.08653037063165896, \"functional effect\": -1.6201, \"times_seen\": 9.0}, {\"site\": 970, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 970, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.028829714845863542, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": 0.08919533457637643, \"functional effect\": -0.172, \"times_seen\": 5.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.005046905394024738, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08712529468999246, \"functional effect\": -2.1772, \"times_seen\": 1.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0008948089987514153, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08737640367425299, \"functional effect\": -2.9803, \"times_seen\": 1.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.004603217205559943, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08715209342978994, \"functional effect\": -0.3972, \"times_seen\": 2.0}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 971, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0029149518865117987, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08760744565416881, \"functional effect\": 0.0648, \"times_seen\": 1.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.005397467089564894, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08710412661243166, \"functional effect\": 0.191, \"times_seen\": 2.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0072201319425153725, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08699415092102812, \"functional effect\": -0.7476, \"times_seen\": 1.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.011658991312972641, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08672690015588444, \"functional effect\": -2.6768, \"times_seen\": 3.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.03085668215908359, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08558048493807029, \"functional effect\": 0.4086, \"times_seen\": 21.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.010813198103059314, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08677775950407182, \"functional effect\": -0.1918, \"times_seen\": 6.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.027365039969813123, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08578785955033794, \"functional effect\": -2.952, \"times_seen\": 4.0}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 972, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004874570460805297, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08713570273066162, \"functional effect\": -2.3569, \"times_seen\": 1.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.019476850176073233, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08625820449052155, \"functional effect\": 0.309, \"times_seen\": 27.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.030219595225938665, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08561828519888809, \"functional effect\": 0.0741, \"times_seen\": 4.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.15080064930988693, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.07875316401014071, \"functional effect\": -0.2778, \"times_seen\": 40.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.05706036792609736, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08404011686395808, \"functional effect\": -0.3156, \"times_seen\": 25.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03016328508178173, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08562162705003114, \"functional effect\": -0.3747, \"times_seen\": 18.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.015500234935645368, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.0864962928295242, \"functional effect\": -0.9486, \"times_seen\": 4.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.09872184613561884, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.0816479515068786, \"functional effect\": -0.3943, \"times_seen\": 19.0}, {\"site\": 973, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0043695077566199446, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.08716621278074106, \"functional effect\": 0.0639, \"times_seen\": 6.0}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.04625628817925169, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.09027927446645127, \"functional effect\": -2.6936, \"times_seen\": 14.0}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.011159378383931714, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.08675693934152999, \"functional effect\": -2.8464, \"times_seen\": 2.0}, {\"site\": 974, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.057287901250065984, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.08402686359921707, \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.024722565051226227, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08594513464664333, \"functional effect\": -0.7606, \"times_seen\": 8.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.012859677475913106, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08665475152704492, \"functional effect\": -0.2445, \"times_seen\": 3.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.003919447443947683, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08766846474039776, \"functional effect\": 0.0876, \"times_seen\": 16.0}, {\"site\": 975, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005129147493395558, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08712032817752074, \"functional effect\": -2.0323, \"times_seen\": 1.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.005176909353769258, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08711744401977746, \"functional effect\": 0.2967, \"times_seen\": 7.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.017478276736481335, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08637778126554804, \"functional effect\": -2.5281, \"times_seen\": 3.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.021030693805184582, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08871445719375909, \"functional effect\": -2.4352, \"times_seen\": 2.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004725010478261241, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.087144736302781, \"functional effect\": -0.0933, \"times_seen\": 1.0}, {\"site\": 976, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02130372449888158, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08873124803398316, \"functional effect\": -2.3506, \"times_seen\": 5.0}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0094542810971489, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.0868595365429904, \"functional effect\": -2.741, \"times_seen\": 2.0}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.054198659197259934, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.08420698304943389, \"functional effect\": -1.4023, \"times_seen\": 3.0}, {\"site\": 977, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.015183026491945337, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.08651531304532348, \"functional effect\": -1.8607, \"times_seen\": 3.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.011101577831432001, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08676041526633704, \"functional effect\": -2.6138, \"times_seen\": 4.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.4642605365689635, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.06337342551975017, \"functional effect\": 0.1042, \"times_seen\": 108.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.09928531735940434, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08161606861637083, \"functional effect\": 0.1214, \"times_seen\": 69.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.8272404531284705, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.04927644175491816, \"functional effect\": -1.0959, \"times_seen\": 48.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.07516509494859477, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08299206709505512, \"functional effect\": 0.4195, \"times_seen\": 50.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.04045551340969432, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.085012973532943, \"functional effect\": -1.8415, \"times_seen\": 45.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03278262551909632, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08944006034912934, \"functional effect\": -0.8577, \"times_seen\": 43.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.7327560760299056, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.052611655968947554, \"functional effect\": 0.4444, \"times_seen\": 120.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.10679495270776639, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.09414819845370971, \"functional effect\": -2.1794, \"times_seen\": 22.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.10590506215302206, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.09409014338580382, \"functional effect\": 0.2322, \"times_seen\": 117.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0583940611129846, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.0839624622409005, \"functional effect\": -0.1087, \"times_seen\": 37.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.06418529903635736, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08362609735051393, \"functional effect\": -0.4181, \"times_seen\": 48.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.35408452478153585, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.11175155962064612, \"functional effect\": -2.6849, \"times_seen\": 38.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01936816394016956, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08626470304527044, \"functional effect\": -0.5073, \"times_seen\": 24.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02236207544298218, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08608587031752808, \"functional effect\": -2.2984, \"times_seen\": 48.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.19095633547427096, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.0765913889136816, \"functional effect\": 0.4298, \"times_seen\": 154.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08330878482860458, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08252491521731294, \"functional effect\": 0.4444, \"times_seen\": 89.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.7584895349371231, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.05168153789568612, \"functional effect\": 0.4444, \"times_seen\": 124.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.22722461200061184, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.10234460494164171, \"functional effect\": 0.3058, \"times_seen\": 44.0}, {\"site\": 978, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.5275403171883275, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.1260285644435893, \"functional effect\": 0.3651, \"times_seen\": 89.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.027752516867013563, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08912876113531215, \"functional effect\": -2.4364, \"times_seen\": 3.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.5721851741313108, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.1299895470491171, \"functional effect\": 0.2506, \"times_seen\": 109.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.03098437331789896, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08557291065009391, \"functional effect\": -1.437, \"times_seen\": 54.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.001692527685343291, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08753324556313216, \"functional effect\": -1.5303, \"times_seen\": 31.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -1.6959682116139672, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.026985236374275863, \"functional effect\": -1.2212, \"times_seen\": 23.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.03329036708069576, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08947154339078364, \"functional effect\": -2.1923, \"times_seen\": 12.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.15430928509666764, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.07856186894544262, \"functional effect\": -0.4425, \"times_seen\": 126.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.017759488858212137, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08851353156195764, \"functional effect\": -2.3799, \"times_seen\": 16.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.5172972819312133, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.061085978000851145, \"functional effect\": -1.0113, \"times_seen\": 44.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06983274665363956, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08329938183919232, \"functional effect\": -2.4314, \"times_seen\": 6.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.04401423417073951, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.0901390828083875, \"functional effect\": -1.0381, \"times_seen\": 68.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.025508186968652424, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08589834582521431, \"functional effect\": -0.3015, \"times_seen\": 32.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.2734382826645758, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.07233531964424507, \"functional effect\": -1.2317, \"times_seen\": 79.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.19208847426161846, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.09988215929329017, \"functional effect\": -1.592, \"times_seen\": 72.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.007489617022991368, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08697790255551545, \"functional effect\": -0.6221, \"times_seen\": 29.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.07514450311567661, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08299325166346834, \"functional effect\": -2.7336, \"times_seen\": 29.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03702708342464007, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08970358350731371, \"functional effect\": -0.4339, \"times_seen\": 74.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.022973639702220782, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08883401365269163, \"functional effect\": -0.4688, \"times_seen\": 63.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.017869083925278934, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08635438582496305, \"functional effect\": -1.9806, \"times_seen\": 18.0}, {\"site\": 979, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04532157622136609, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.09022080210421034, \"functional effect\": -1.5874, \"times_seen\": 20.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02273698901254385, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08606350206453452, \"functional effect\": -1.4676, \"times_seen\": 5.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.8037359799590369, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.05008583187939256, \"functional effect\": -1.359, \"times_seen\": 21.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.010415680607130608, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08806411241170349, \"functional effect\": -2.8738, \"times_seen\": 3.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.00924566400013134, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08687209754447481, \"functional effect\": -2.0455, \"times_seen\": 8.0}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 980, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010490190641282782, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.0867971905002996, \"functional effect\": -3.1267, \"times_seen\": 1.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.08273669717973395, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08255764621399782, \"functional effect\": 0.0263, \"times_seen\": 15.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0049365486743513255, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08713195945918928, \"functional effect\": -1.2901, \"times_seen\": 1.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03089762189303919, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08557805643275597, \"functional effect\": -0.1847, \"times_seen\": 8.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.030882366186887708, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08557896137839432, \"functional effect\": -2.9773, \"times_seen\": 5.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0017786072313120851, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08753846845959448, \"functional effect\": -2.6755, \"times_seen\": 1.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.008186947603703951, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08693587170789946, \"functional effect\": -2.6018, \"times_seen\": 2.0}, {\"site\": 981, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.025040437510118987, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08896136802483676, \"functional effect\": -1.3383, \"times_seen\": 2.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.08050436639445799, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08268548933207955, \"functional effect\": -1.3752, \"times_seen\": 16.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.024375410473345616, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08596581804550292, \"functional effect\": -0.6096, \"times_seen\": 6.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.01206074691804209, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08670275217849298, \"functional effect\": -0.8612, \"times_seen\": 1.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.005818244226018602, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08778392517238091, \"functional effect\": -1.5046, \"times_seen\": 1.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -2.4826541525777093, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.015642643984335788, \"functional effect\": -0.1631, \"times_seen\": 39.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.8331041966874678, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.15575890402720868, \"functional effect\": -0.6573, \"times_seen\": 31.0}, {\"site\": 982, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006309784036610514, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08704906199532578, \"functional effect\": -3.054, \"times_seen\": 1.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.006332215298141407, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08704770855260882, \"functional effect\": -0.7122, \"times_seen\": 3.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.04723387502258669, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.0846144852497723, \"functional effect\": -0.7656, \"times_seen\": 1.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.027114260365930697, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08908933878484808, \"functional effect\": -0.0602, \"times_seen\": 4.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 1.2014149605283198, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.20105990375187854, \"functional effect\": -0.3265, \"times_seen\": 26.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": 1.7131554717692854, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.2866650281532583, \"functional effect\": -2.5728, \"times_seen\": 12.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.09860869009930846, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08165435571610942, \"functional effect\": -0.5062, \"times_seen\": 26.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0958925130241067, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.0818082320343087, \"functional effect\": -0.1729, \"times_seen\": 92.0}, {\"site\": 983, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.021086660087040313, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08871789874895972, \"functional effect\": 0.0755, \"times_seen\": 12.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.012524155574816013, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08819291075249584, \"functional effect\": -0.0256, \"times_seen\": 38.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.02598854710732442, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08901985082641968, \"functional effect\": -2.0631, \"times_seen\": 1.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00012407258488254493, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.0874230955710752, \"functional effect\": -0.6662, \"times_seen\": 13.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.020096266078884692, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08865701580395316, \"functional effect\": -2.2332, \"times_seen\": 10.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0032436712183066354, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08723426126307746, \"functional effect\": -0.1031, \"times_seen\": 7.0}, {\"site\": 984, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0208783946169549, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08617444735586541, \"functional effect\": 0.1539, \"times_seen\": 8.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.06098184874154346, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08381199227702145, \"functional effect\": -1.0405, \"times_seen\": 23.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.851739069906759, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.04844673586318395, \"functional effect\": -0.9251, \"times_seen\": 45.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04725126506963562, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08461346532458401, \"functional effect\": -1.4406, \"times_seen\": 15.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.002331416600379591, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08728943926047925, \"functional effect\": -0.801, \"times_seen\": 21.0}, {\"site\": 985, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003188746025890214, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08723758244299215, \"functional effect\": -1.4355, \"times_seen\": 5.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.016325251157506795, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08644684340157233, \"functional effect\": -2.014, \"times_seen\": 4.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.00017073885657981056, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08742026777737433, \"functional effect\": -1.1198, \"times_seen\": 1.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0006422806179488367, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08739169932049204, \"functional effect\": -3.2259, \"times_seen\": 1.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.8055881349931076, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.15281631493447484, \"functional effect\": -1.5174, \"times_seen\": 19.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0026706954821801797, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.0872689137991435, \"functional effect\": -2.7458, \"times_seen\": 2.0}, {\"site\": 986, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.005931616994485922, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08707188275799774, \"functional effect\": -2.5217, \"times_seen\": 13.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.03121118783520617, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.0855594582902823, \"functional effect\": 0.3188, \"times_seen\": 8.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.042155814655237614, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08491283974502017, \"functional effect\": 0.3632, \"times_seen\": 20.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.1533462097989996, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.07861433065956425, \"functional effect\": -0.5187, \"times_seen\": 43.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.16765822319137913, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.07783830599588472, \"functional effect\": -1.9929, \"times_seen\": 37.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04947615489981826, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08448307702623668, \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.3494928810280371, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.06862078619484203, \"functional effect\": 0.3215, \"times_seen\": 30.0}, {\"site\": 987, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.003030973709244778, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08761449134571359, \"functional effect\": -1.6432, \"times_seen\": 5.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.009773660263122463, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08684030998771855, \"functional effect\": -1.6111, \"times_seen\": 3.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.021233471023767284, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08615324069256394, \"functional effect\": -2.2801, \"times_seen\": 7.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0004034556054070624, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08740616741715744, \"functional effect\": -0.113, \"times_seen\": 2.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.1043296256105004, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08133120057641446, \"functional effect\": -0.6941, \"times_seen\": 22.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07926087883793435, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08275678832286414, \"functional effect\": -0.3699, \"times_seen\": 12.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.011979501080900554, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08670763500947011, \"functional effect\": -1.7365, \"times_seen\": 2.0}, {\"site\": 988, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0361956875777475, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.08965190404661108, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.007136650443588148, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.0869991849802259, \"functional effect\": -2.8081, \"times_seen\": 1.0}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.02482868940367716, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.08894831189145284, \"functional effect\": -1.6191, \"times_seen\": 1.0}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 989, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.002311989358154685, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.0872906147025858, \"functional effect\": -2.3991, \"times_seen\": 2.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010806357308513823, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.08677817097719294, \"functional effect\": -0.2947, \"times_seen\": 8.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005373288267176275, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.0871055864447562, \"functional effect\": -1.1686, \"times_seen\": 1.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 7.285299013263423e-05, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.0874350294988271, \"functional effect\": 0.3956, \"times_seen\": 1.0}, {\"site\": 990, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03757694013089908, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.08518276712576871, \"functional effect\": 0.2884, \"times_seen\": 22.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.027322802235924273, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08910221759820339, \"functional effect\": -2.5788, \"times_seen\": 4.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.026649206477508958, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08906062539411126, \"functional effect\": -2.2389, \"times_seen\": 9.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.15863527144018158, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.09759273857813583, \"functional effect\": -2.566, \"times_seen\": 8.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.021609719159940602, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08613077525888267, \"functional effect\": -2.6505, \"times_seen\": 5.0}, {\"site\": 991, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0029129119101033085, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08725426330848143, \"functional effect\": -2.8487, \"times_seen\": 1.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.005427861241051645, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08710229155508639, \"functional effect\": -2.973, \"times_seen\": 9.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.036938917710041104, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08522044697713389, \"functional effect\": -2.282, \"times_seen\": 8.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.008106812923649679, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.0869407007060941, \"functional effect\": -2.4317, \"times_seen\": 2.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012102553580505227, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08670023972778554, \"functional effect\": -2.8796, \"times_seen\": 20.0}, {\"site\": 992, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 993, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 993, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.023287088804240887, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": 0.08885331639244098, \"functional effect\": -2.7368, \"times_seen\": 6.0}, {\"site\": 993, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00794225668594266, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": 0.08695061787511237, \"functional effect\": -2.6411, \"times_seen\": 2.0}, {\"site\": 994, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 994, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.003922141669524065, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": 0.08719324639011852, \"functional effect\": -2.9663, \"times_seen\": 1.0}, {\"site\": 994, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.010127715997253517, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": 0.08681900088470357, \"functional effect\": -0.4513, \"times_seen\": 6.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.01804006739767311, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.0863441519935565, \"functional effect\": -0.2182, \"times_seen\": 5.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.017467057086290604, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08849559184151816, \"functional effect\": -0.5475, \"times_seen\": 4.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.5490009945035365, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.12791730381251948, \"functional effect\": -0.1864, \"times_seen\": 58.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0037091620857072675, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08765568722990694, \"functional effect\": -2.9961, \"times_seen\": 5.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03277797797752003, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08546658977259411, \"functional effect\": 0.2187, \"times_seen\": 8.0}, {\"site\": 995, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.006013695987697258, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08706692913372159, \"functional effect\": -2.0619, \"times_seen\": 16.0}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.039656934903098, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.0898672509770162, \"functional effect\": -2.9368, \"times_seen\": 14.0}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.01612934550544827, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08841357401506805, \"functional effect\": -1.7115, \"times_seen\": 14.0}, {\"site\": 996, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.008349511527993193, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08692607626266824, \"functional effect\": -2.3977, \"times_seen\": 1.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.00030989791472730736, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08744939686836563, \"functional effect\": -2.1814, \"times_seen\": 1.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.007855207081442831, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08695586447611776, \"functional effect\": -2.3084, \"times_seen\": 3.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011917139949635207, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08671138306635044, \"functional effect\": -2.6788, \"times_seen\": 2.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.08358076841455388, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.09264539734989682, \"functional effect\": -2.9436, \"times_seen\": 3.0}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 997, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0015349393525505022, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08733764296617368, \"functional effect\": -2.8379, \"times_seen\": 1.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0018459837342199442, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08731881504057779, \"functional effect\": -2.4962, \"times_seen\": 7.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0012685599700401748, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08735377048772003, \"functional effect\": -2.0806, \"times_seen\": 1.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.010601344646273094, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08807544633223317, \"functional effect\": 0.0572, \"times_seen\": 4.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0608064726184738, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08382218120488555, \"functional effect\": -2.5626, \"times_seen\": 3.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.867853602085259, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.1595561307309437, \"functional effect\": -2.0474, \"times_seen\": 4.0}, {\"site\": 998, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01915048036827202, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.0862777202283432, \"functional effect\": -1.1479, \"times_seen\": 8.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01778218515229268, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08851492405648191, \"functional effect\": -1.4619, \"times_seen\": 2.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.015235298272487329, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08835880053806977, \"functional effect\": 0.3082, \"times_seen\": 11.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01091139676089206, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08677185307945211, \"functional effect\": -0.8236, \"times_seen\": 20.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.20203231305741093, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.07600562658227007, \"functional effect\": -2.6935, \"times_seen\": 14.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.05753266451961522, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08401260906534874, \"functional effect\": -2.3498, \"times_seen\": 12.0}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 999, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.007613715896280625, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08697042114386692, \"functional effect\": -2.6958, \"times_seen\": 3.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.049437518678173115, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.09047856541285634, \"functional effect\": -2.9328, \"times_seen\": 2.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04283906192610344, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08487263531615193, \"functional effect\": -0.1891, \"times_seen\": 13.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.4816746233765227, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.12208492472174484, \"functional effect\": 0.4444, \"times_seen\": 28.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0021392988798526738, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08730106400739847, \"functional effect\": -1.803, \"times_seen\": 1.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.014930546202597159, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08653045506919348, \"functional effect\": -0.0835, \"times_seen\": 20.0}, {\"site\": 1000, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008828398624189977, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08689722687531765, \"functional effect\": -0.1014, \"times_seen\": 2.0}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.007831511605400767, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.08695729269030446, \"functional effect\": -2.8704, \"times_seen\": 3.0}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.007241651794797155, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.08699285328898415, \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1001, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.1297210176572196, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.07991229669963205, \"functional effect\": -2.6499, \"times_seen\": 2.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.004877628162753178, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08713551805218275, \"functional effect\": -2.2327, \"times_seen\": 1.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.008472778294225481, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08691864944114891, \"functional effect\": -0.8476, \"times_seen\": 62.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.022942131117302058, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08605126524921093, \"functional effect\": -2.1267, \"times_seen\": 11.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.004509101611723331, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08770430366665563, \"functional effect\": -1.2242, \"times_seen\": 20.0}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1002, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -4.998010569800338e-05, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08742758547367958, \"functional effect\": -2.6955, \"times_seen\": 15.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05431538490220358, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08420017029860151, \"functional effect\": -0.0438, \"times_seen\": 21.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.797729761222843, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.025147391772289952, \"functional effect\": -1.2634, \"times_seen\": 46.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.029305338649651708, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.0856725599319187, \"functional effect\": -2.1087, \"times_seen\": 5.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.022797143172670134, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08605991366254512, \"functional effect\": 0.2832, \"times_seen\": 3.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.00855803640817622, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08795079219778634, \"functional effect\": 0.1799, \"times_seen\": 29.0}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1003, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03838228276049933, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08513522958807279, \"functional effect\": -0.6323, \"times_seen\": 11.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.015472659500212716, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.0883733390775234, \"functional effect\": -2.9151, \"times_seen\": 4.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.011423293068809421, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.08674107019694682, \"functional effect\": -2.7839, \"times_seen\": 4.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.005032376779997411, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.0871261720868895, \"functional effect\": -2.6162, \"times_seen\": 1.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005370214778797689, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.08710577201293605, \"functional effect\": -1.62, \"times_seen\": 1.0}, {\"site\": 1004, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.01311048703516375, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.0882287608705056, \"functional effect\": -1.0404, \"times_seen\": 11.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.6293254732143271, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.13524131173622003, \"functional effect\": -1.0029, \"times_seen\": 11.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.015066998810955117, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.08652227125514977, \"functional effect\": -1.1313, \"times_seen\": 6.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.001327747918539214, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.08751111592408378, \"functional effect\": -2.9835, \"times_seen\": 1.0}, {\"site\": 1005, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.06306393462310411, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08369112272370507, \"functional effect\": -2.336, \"times_seen\": 6.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.022264839065099334, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08879037994035245, \"functional effect\": -1.0774, \"times_seen\": 19.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.006644044748401709, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08783418718925146, \"functional effect\": -0.1907, \"times_seen\": 75.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.007121325741999949, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08700010911428852, \"functional effect\": -3.0194, \"times_seen\": 1.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.9658173673774284, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.04476344804589942, \"functional effect\": -1.5244, \"times_seen\": 21.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04377904642764381, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.0901243895579316, \"functional effect\": -2.2375, \"times_seen\": 7.0}, {\"site\": 1006, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.032532606201837774, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.08548112705994108, \"functional effect\": -0.0605, \"times_seen\": 26.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.018315896108836605, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.08632764544232908, \"functional effect\": -0.3591, \"times_seen\": 8.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.08328988773713487, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.09262671977867516, \"functional effect\": -0.2318, \"times_seen\": 19.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.008008684448478468, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.08694661439422369, \"functional effect\": -0.1312, \"times_seen\": 38.0}, {\"site\": 1007, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.25490081499577294, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.07327076716233398, \"functional effect\": -0.0277, \"times_seen\": 29.0}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.058235477560385954, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.0839716920483124, \"functional effect\": -1.6652, \"times_seen\": 15.0}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.022443656848328438, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.08608100247815978, \"functional effect\": -0.8592, \"times_seen\": 25.0}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01834688707487021, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.08632579103213375, \"functional effect\": -0.8773, \"times_seen\": 4.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04149866884711647, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.08495152624874004, \"functional effect\": -0.9178, \"times_seen\": 13.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.007957330388373875, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.08694970939420973, \"functional effect\": -0.3205, \"times_seen\": 2.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.17319640829135777, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.09858273075448863, \"functional effect\": -2.4375, \"times_seen\": 5.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.008013245197230926, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.08694633953292237, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1009, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.024794640015715262, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.0859408410588644, \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.017021903528920267, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08640510979975476, \"functional effect\": -0.6953, \"times_seen\": 7.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0002538821960749717, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08741522984256538, \"functional effect\": -0.9232, \"times_seen\": 2.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.05497621355699665, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.09082659208706506, \"functional effect\": -2.0467, \"times_seen\": 12.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.8021102375667937, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.3048967302499204, \"functional effect\": -1.7187, \"times_seen\": 17.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.004442612811453014, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08770026177325979, \"functional effect\": -1.9471, \"times_seen\": 1.0}, {\"site\": 1010, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.06338107313699352, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08367272745616523, \"functional effect\": -2.111, \"times_seen\": 4.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.15439619237071062, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.07855713655776626, \"functional effect\": -1.1865, \"times_seen\": 41.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.010464000951534007, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08679876617087373, \"functional effect\": -0.8212, \"times_seen\": 18.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02053480345566072, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08619497304125538, \"functional effect\": 0.4444, \"times_seen\": 71.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.009036958246262418, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08797999348152676, \"functional effect\": -0.7817, \"times_seen\": 13.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.015932501863002903, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08647038029442562, \"functional effect\": -0.9301, \"times_seen\": 7.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0014441364345497364, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08751817611316401, \"functional effect\": -0.6521, \"times_seen\": 19.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.11188785491889676, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08090622342822303, \"functional effect\": -0.1905, \"times_seen\": 38.0}, {\"site\": 1011, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.009245416563631145, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08687211244390193, \"functional effect\": -0.8081, \"times_seen\": 3.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.030757038884475254, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08931457196650107, \"functional effect\": -3.0886, \"times_seen\": 2.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.023426895027921578, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08602235578522231, \"functional effect\": -2.2673, \"times_seen\": 5.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.022310622409449955, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08879319771190346, \"functional effect\": -0.2662, \"times_seen\": 34.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0013140491880232151, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08735101620358562, \"functional effect\": -2.0108, \"times_seen\": 7.0}, {\"site\": 1012, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.021621802369663063, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08613005387852632, \"functional effect\": -2.7786, \"times_seen\": 5.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0038917774366572116, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.08766678332906179, \"functional effect\": -1.9172, \"times_seen\": 1.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.01640792763951682, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.08843064818503081, \"functional effect\": -0.5694, \"times_seen\": 4.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.022974361799926978, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.0888340581159023, \"functional effect\": -0.1187, \"times_seen\": 11.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.15458642627208644, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.07854677868939196, \"functional effect\": 0.1466, \"times_seen\": 56.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.1645054000566049, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.0979906390232253, \"functional effect\": 0.4444, \"times_seen\": 145.0}, {\"site\": 1013, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.044392157089822235, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.09016269839350659, \"functional effect\": 0.3904, \"times_seen\": 64.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.2574924006507153, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.07313926534552553, \"functional effect\": -0.3865, \"times_seen\": 15.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.041771926475924044, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.08493543729460605, \"functional effect\": 0.2148, \"times_seen\": 5.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.21583972877211577, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.07528167913706368, \"functional effect\": 0.3651, \"times_seen\": 40.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.007201901492137585, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.0878681572015234, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1014, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.007124012503281017, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.08699994709230859, \"functional effect\": -0.3501, \"times_seen\": 1.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.06373128725237948, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08365241837282478, \"functional effect\": -1.9964, \"times_seen\": 16.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.09488552820383757, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08186535318757908, \"functional effect\": -1.319, \"times_seen\": 22.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.08379538479418122, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08249708546230132, \"functional effect\": -0.0369, \"times_seen\": 50.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.009057254964155543, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08688344336357849, \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0043302512946801815, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08716858464975902, \"functional effect\": -1.1885, \"times_seen\": 1.0}, {\"site\": 1015, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.3849757878626333, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.11417020732760276, \"functional effect\": -0.4457, \"times_seen\": 81.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.015435468611459679, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08650017595972884, \"functional effect\": -2.4929, \"times_seen\": 1.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -2.4871433943562757, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.015594044339530917, \"functional effect\": -1.5594, \"times_seen\": 21.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.00953397863733653, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.0868547383701229, \"functional effect\": -0.6401, \"times_seen\": 29.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.019019520329959693, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08628555240775038, \"functional effect\": -2.7786, \"times_seen\": 3.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02969605963323364, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08564936061848091, \"functional effect\": -1.9902, \"times_seen\": 4.0}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1016, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.034207510579549086, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08538194488112669, \"functional effect\": -1.9743, \"times_seen\": 1.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006333262962921066, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08704764533981423, \"functional effect\": -2.9948, \"times_seen\": 1.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.010878983614041457, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08809239761327659, \"functional effect\": -0.6982, \"times_seen\": 17.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0818284100238912, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.09253293464823328, \"functional effect\": -0.958, \"times_seen\": 28.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.031064041476989664, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08933357994948594, \"functional effect\": -1.0272, \"times_seen\": 40.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.2668727740041287, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.07266525801597065, \"functional effect\": -0.2906, \"times_seen\": 12.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.057134666954423555, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08403578889577136, \"functional effect\": -0.8455, \"times_seen\": 81.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.03986395746634919, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08504783900351208, \"functional effect\": -1.6341, \"times_seen\": 13.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.017551774412477534, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08637338088688823, \"functional effect\": -0.6665, \"times_seen\": 6.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -2.663050920743325, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.013804011830921753, \"functional effect\": -1.8672, \"times_seen\": 18.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04815296609939275, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08456059745669481, \"functional effect\": -2.4464, \"times_seen\": 14.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.027677715722295285, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08576926873507552, \"functional effect\": -0.9902, \"times_seen\": 15.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.03823917731236904, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08514367483748946, \"functional effect\": -0.6127, \"times_seen\": 11.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.007626891883088684, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.0878940452944661, \"functional effect\": -2.7603, \"times_seen\": 5.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.7021317771755579, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.1422414778337867, \"functional effect\": -0.7244, \"times_seen\": 22.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.08752397642101518, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.0822841500962811, \"functional effect\": -0.4314, \"times_seen\": 74.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.5409910117385655, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.06009094142900657, \"functional effect\": -0.2797, \"times_seen\": 111.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.35979189422463465, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.0681326651509229, \"functional effect\": -0.3397, \"times_seen\": 101.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.2858109622373265, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.07171761809758281, \"functional effect\": -0.6024, \"times_seen\": 127.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.007359946311407156, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08698572055798456, \"functional effect\": -0.2591, \"times_seen\": 19.0}, {\"site\": 1017, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04532217751379882, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08472668118497166, \"functional effect\": -0.4778, \"times_seen\": 10.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.007728927590801076, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.0869634760797837, \"functional effect\": -0.9083, \"times_seen\": 1.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.045351084131309345, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.08472498357240606, \"functional effect\": -0.8606, \"times_seen\": 10.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.22724233000481608, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.07468902193975231, \"functional effect\": -0.9573, \"times_seen\": 27.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014175582435299112, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.08657574839343125, \"functional effect\": -0.9223, \"times_seen\": 7.0}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1018, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06731800745929752, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.0834447063103525, \"functional effect\": -0.5607, \"times_seen\": 20.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.026906878511265834, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08907653345596274, \"functional effect\": -2.8753, \"times_seen\": 1.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.021874571204474072, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08611496469775623, \"functional effect\": -2.4657, \"times_seen\": 6.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.012638070060905057, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08819987469599197, \"functional effect\": -2.9181, \"times_seen\": 1.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.023038375183933896, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08604552484862116, \"functional effect\": -0.8362, \"times_seen\": 34.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.011630487531630526, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08672861366355522, \"functional effect\": -2.3735, \"times_seen\": 9.0}, {\"site\": 1019, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.031610192978057526, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08936740477286051, \"functional effect\": -2.7325, \"times_seen\": 2.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.04105368966757657, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.08995429868270097, \"functional effect\": -1.4309, \"times_seen\": 27.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.021865210098736296, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.08611552346719997, \"functional effect\": 0.1589, \"times_seen\": 29.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0003350445127862438, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.08745092115030771, \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.3269832255080263, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.21934376034896153, \"functional effect\": 0.0756, \"times_seen\": 79.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.17862915100585902, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.07724863203338846, \"functional effect\": 0.4444, \"times_seen\": 16.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.17857321475458338, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.0989508260363685, \"functional effect\": -0.5625, \"times_seen\": 83.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.18665192131566763, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.0768202476509581, \"functional effect\": 0.031, \"times_seen\": 63.0}, {\"site\": 1020, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.4685692878659685, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.06318443687940355, \"functional effect\": 0.3044, \"times_seen\": 54.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.024157252595486726, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08597881839410754, \"functional effect\": -2.1134, \"times_seen\": 8.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.017085355408143175, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08640130965774837, \"functional effect\": -1.4723, \"times_seen\": 25.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.014893558223683741, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08833787292418789, \"functional effect\": -1.4396, \"times_seen\": 23.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.015220823497148048, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08651304647005321, \"functional effect\": -2.4232, \"times_seen\": 1.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0013186384415333774, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.0875105633624135, \"functional effect\": -1.5057, \"times_seen\": 1.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.10807820464679421, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08112015064218298, \"functional effect\": -0.5949, \"times_seen\": 24.0}, {\"site\": 1021, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0036592774190068013, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08720913476215277, \"functional effect\": -2.3092, \"times_seen\": 1.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.022643063379858986, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.08606910534991125, \"functional effect\": -0.9721, \"times_seen\": 11.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.025273748257820583, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.08897575590382732, \"functional effect\": -2.9406, \"times_seen\": 1.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.009874494654505513, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.08683424066360286, \"functional effect\": -2.8946, \"times_seen\": 2.0}, {\"site\": 1022, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.010007747980624614, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.0880392151567616, \"functional effect\": -2.7023, \"times_seen\": 8.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.010611685779081512, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08678988126841261, \"functional effect\": -0.3951, \"times_seen\": 1.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01353924130065544, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08661394347975404, \"functional effect\": -2.9787, \"times_seen\": 2.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01681749220079554, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08641735315962049, \"functional effect\": -0.2546, \"times_seen\": 19.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.014120343388667151, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08829054077753881, \"functional effect\": -1.8377, \"times_seen\": 25.0}, {\"site\": 1023, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.7126319610820956, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.0533506768745346, \"functional effect\": -2.9637, \"times_seen\": 6.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.022820034818146737, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08605854813667314, \"functional effect\": -2.9022, \"times_seen\": 5.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.09715680350248425, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08173657166291709, \"functional effect\": -1.9119, \"times_seen\": 85.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.06442973914441757, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08361192953260832, \"functional effect\": -0.6409, \"times_seen\": 34.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.12156639462866958, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08036526825818553, \"functional effect\": -1.5114, \"times_seen\": 35.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.051066515374023874, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08438999809097475, \"functional effect\": -1.0087, \"times_seen\": 33.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.7167144034850763, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.14368653229954606, \"functional effect\": -0.8598, \"times_seen\": 48.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.08717309512307145, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08230416505430235, \"functional effect\": -1.9465, \"times_seen\": 35.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.12622923078918863, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08010594445765486, \"functional effect\": -0.8568, \"times_seen\": 38.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.1236750207954325, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.19051247390340173, \"functional effect\": -2.4041, \"times_seen\": 54.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.012337349122471135, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08668613059676818, \"functional effect\": -2.8558, \"times_seen\": 10.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.21502307461416337, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.07532430526268362, \"functional effect\": 0.0517, \"times_seen\": 144.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.028903944862461426, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08569639949372401, \"functional effect\": 0.425, \"times_seen\": 43.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.37530296509056044, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.06740406364654906, \"functional effect\": -1.7085, \"times_seen\": 58.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.004515816048838632, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08770471185160489, \"functional effect\": -2.5785, \"times_seen\": 10.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010919290240359994, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08677137832217664, \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.061817379178206726, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.09125830862917689, \"functional effect\": -0.8558, \"times_seen\": 117.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -2.0912954122894694, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.020517331766069985, \"functional effect\": -0.8175, \"times_seen\": 180.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.026170441875137843, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.0858589240869042, \"functional effect\": -2.3363, \"times_seen\": 33.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.010515429161496212, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08807020141273046, \"functional effect\": -2.0872, \"times_seen\": 8.0}, {\"site\": 1024, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0037301997650882684, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08765696545270316, \"functional effect\": -2.6245, \"times_seen\": 12.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.019072510918720583, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.08628238317369623, \"functional effect\": -0.1676, \"times_seen\": 1.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.1214262917282736, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.040186536531743366, \"functional effect\": -2.9637, \"times_seen\": 4.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.029756335686094437, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.08564578224786479, \"functional effect\": -2.6429, \"times_seen\": 4.0}, {\"site\": 1025, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03393333199829476, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.08539817292965385, \"functional effect\": -2.3767, \"times_seen\": 6.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01359381522211252, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08661066713027449, \"functional effect\": -2.451, \"times_seen\": 1.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.5744896895672171, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.029355866602937337, \"functional effect\": -1.349, \"times_seen\": 47.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0010186854844259903, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08736890145318045, \"functional effect\": -2.596, \"times_seen\": 2.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.011845216201893714, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08671570606111158, \"functional effect\": -2.2197, \"times_seen\": 1.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.013513750748845081, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08661547384941369, \"functional effect\": -2.5108, \"times_seen\": 1.0}, {\"site\": 1026, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03779707764112411, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08975147282151234, \"functional effect\": -1.3142, \"times_seen\": 25.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0019367129098556916, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.08754806237027847, \"functional effect\": -0.1609, \"times_seen\": 17.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.04311939509711043, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.09008319091068179, \"functional effect\": -2.5245, \"times_seen\": 4.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.06825003942488327, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.09166611786941221, \"functional effect\": -2.9561, \"times_seen\": 3.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0008876311274221994, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.08748442335482035, \"functional effect\": -2.4774, \"times_seen\": 1.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.002046331924014225, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.08730668985030922, \"functional effect\": -2.6183, \"times_seen\": 1.0}, {\"site\": 1027, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.019272391338306483, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.08860640120987812, \"functional effect\": -2.7814, \"times_seen\": 1.0}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.1186292704385612, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.189847330332777, \"functional effect\": -2.9297, \"times_seen\": 11.0}, {\"site\": 1028, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.020259864082200256, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.08866706985747823, \"functional effect\": -2.8256, \"times_seen\": 1.0}, {\"site\": 1029, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04297116764097279, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": 0.09007393592891635, \"functional effect\": -2.9152, \"times_seen\": 1.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02275562325509194, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08882059029418649, \"functional effect\": -1.4429, \"times_seen\": 9.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.007778978882282673, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08696045911593185, \"functional effect\": -2.6888, \"times_seen\": 1.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.00976396402902452, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08684089363622396, \"functional effect\": -2.434, \"times_seen\": 2.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0018415016621760281, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08731908631747044, \"functional effect\": -2.0594, \"times_seen\": 1.0}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1030, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010281617871133082, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08680973981851463, \"functional effect\": -2.5961, \"times_seen\": 2.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -3.957645728539927, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.005627214285063714, \"functional effect\": -1.0692, \"times_seen\": 6.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.006955749209528501, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.08701009459469032, \"functional effect\": -1.2398, \"times_seen\": 15.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.04609242032354609, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.08468145839199596, \"functional effect\": 0.3887, \"times_seen\": 4.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.003485026010771138, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.08721966868087377, \"functional effect\": 0.3651, \"times_seen\": 30.0}, {\"site\": 1031, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.023606773978069828, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.08601163096396448, \"functional effect\": -0.9591, \"times_seen\": 1.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.015733008863175923, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08838928840708792, \"functional effect\": -2.6997, \"times_seen\": 3.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0011947801840773795, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.0873582378956668, \"functional effect\": -2.4806, \"times_seen\": 1.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0149540009692632, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08652904830263651, \"functional effect\": -2.7178, \"times_seen\": 5.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.02490946033007876, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08593400152490646, \"functional effect\": -2.6825, \"times_seen\": 7.0}, {\"site\": 1032, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.008849994751134531, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.086895926094873, \"functional effect\": -2.465, \"times_seen\": 5.0}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.015040022030220722, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.08652388913980089, \"functional effect\": -2.558, \"times_seen\": 5.0}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0049255043513926865, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.08713262648663198, \"functional effect\": -2.933, \"times_seen\": 1.0}, {\"site\": 1033, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.010618618615609428, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.08678946420271519, \"functional effect\": -2.6751, \"times_seen\": 1.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.008412012319889367, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08692231051123304, \"functional effect\": -0.7186, \"times_seen\": 1.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.026753577963842493, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.0890670687004424, \"functional effect\": -1.4326, \"times_seen\": 2.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.006302028251503675, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.0870495299636865, \"functional effect\": -2.7668, \"times_seen\": 6.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009328564427780288, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.0868671058262507, \"functional effect\": -2.3881, \"times_seen\": 2.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.05678882101417209, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08405593654960987, \"functional effect\": -0.5421, \"times_seen\": 18.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004214969017031654, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08717555035921187, \"functional effect\": -2.4226, \"times_seen\": 1.0}, {\"site\": 1034, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.017358903387944696, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08848895789149677, \"functional effect\": -1.0333, \"times_seen\": 27.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0015020586471303431, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08752168991755148, \"functional effect\": -1.7715, \"times_seen\": 1.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.09348957078747944, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.09328390007186263, \"functional effect\": -0.3826, \"times_seen\": 14.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 1.2537206339510987, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.20848319163587611, \"functional effect\": -0.3265, \"times_seen\": 20.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.001012509743592097, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08749199626957783, \"functional effect\": 0.0722, \"times_seen\": 25.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.2405468992844692, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.10329406337567834, \"functional effect\": 0.2803, \"times_seen\": 49.0}, {\"site\": 1035, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.03275709813137535, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08943847778952094, \"functional effect\": -0.1467, \"times_seen\": 12.0}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.004891986625885237, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.08713465083779437, \"functional effect\": -3.0763, \"times_seen\": 1.0}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.001270495776598137, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.08750764318779727, \"functional effect\": -2.479, \"times_seen\": 2.0}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.003412897119826323, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.08722402941897747, \"functional effect\": -2.9133, \"times_seen\": 1.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.06622455496861449, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08350797498851367, \"functional effect\": 0.0238, \"times_seen\": 22.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.10396631077430765, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08135168484505084, \"functional effect\": -0.9927, \"times_seen\": 22.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03828394142048364, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08514103303071234, \"functional effect\": -2.6141, \"times_seen\": 2.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.021782801033785087, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08612044266512947, \"functional effect\": -2.0361, \"times_seen\": 5.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.02674842220886995, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.0890667504022929, \"functional effect\": -2.0321, \"times_seen\": 9.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04621965358317489, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.09027698201886615, \"functional effect\": -0.3684, \"times_seen\": 22.0}, {\"site\": 1037, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.009239429397165136, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08799234166328226, \"functional effect\": -0.3271, \"times_seen\": 16.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0379982703513797, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08515789365437694, \"functional effect\": -0.9511, \"times_seen\": 126.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0015373827619201677, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08733749504757107, \"functional effect\": -2.4891, \"times_seen\": 1.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.028530106906561773, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08917681309058609, \"functional effect\": -2.072, \"times_seen\": 29.0}, {\"site\": 1038, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.026635768127279597, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08905979582010724, \"functional effect\": -0.8159, \"times_seen\": 1.0}, {\"site\": 1039, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.028045045850995005, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": 0.085747433471846, \"functional effect\": -0.7176, \"times_seen\": 16.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.004908305244703466, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08713366524550299, \"functional effect\": -2.6105, \"times_seen\": 3.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.010259907853976154, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.0868110461618982, \"functional effect\": -1.6803, \"times_seen\": 6.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00389290584550153, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08719501335553008, \"functional effect\": -1.0532, \"times_seen\": 1.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03482031169066643, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08956647621429806, \"functional effect\": -2.4504, \"times_seen\": 5.0}, {\"site\": 1040, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.002816319138680796, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08726010543937063, \"functional effect\": -2.8414, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.013794660724080664, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.08659861042277446, \"functional effect\": -1.4106, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.244707699738409, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.03689514117882803, \"functional effect\": -2.8731, \"times_seen\": 4.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01485980159140803, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.08653469831764075, \"functional effect\": -2.2404, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.025299766659457247, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.0889773605588394, \"functional effect\": -2.9256, \"times_seen\": 1.0}, {\"site\": 1041, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.04111411712959284, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.08497417317595829, \"functional effect\": -2.7309, \"times_seen\": 8.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.058232843985991316, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.09103184872962113, \"functional effect\": -1.8822, \"times_seen\": 23.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.05494923825513774, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.09082489384054485, \"functional effect\": -2.2214, \"times_seen\": 10.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.1667381035217168, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.0778879654167921, \"functional effect\": -1.1793, \"times_seen\": 26.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.213967204440453, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.10140843409639234, \"functional effect\": -1.018, \"times_seen\": 15.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04339555696682092, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.08483990345587432, \"functional effect\": 0.1656, \"times_seen\": 52.0}, {\"site\": 1042, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07259531971791251, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.09194262497110159, \"functional effect\": -1.3548, \"times_seen\": 10.0}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05988680621210063, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.09113627105984107, \"functional effect\": -1.1822, \"times_seen\": 12.0}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -1.2704204220718236, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.036243395297690155, \"functional effect\": -2.8615, \"times_seen\": 4.0}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02753794533691275, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.08577757858860079, \"functional effect\": -1.7674, \"times_seen\": 7.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.008455439856113802, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.0869196940435335, \"functional effect\": -3.0069, \"times_seen\": 1.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0499670230666831, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08445433706539265, \"functional effect\": -2.5979, \"times_seen\": 5.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.07790396310907903, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.09228156681501715, \"functional effect\": -2.3915, \"times_seen\": 11.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.017985863764966307, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08852742140977805, \"functional effect\": -2.6773, \"times_seen\": 5.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06510820918914156, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08357261779242921, \"functional effect\": -0.3012, \"times_seen\": 10.0}, {\"site\": 1044, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00486551983682833, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": 0.08713624937075655, \"functional effect\": -3.1124, \"times_seen\": 1.0}, {\"site\": 1045, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004186723181612934, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": 0.08717725714427933, \"functional effect\": -3.0457, \"times_seen\": 1.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.008476467941043689, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08691842714974346, \"functional effect\": -2.8127, \"times_seen\": 2.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.012225760056945973, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08817467152162273, \"functional effect\": -2.1582, \"times_seen\": 13.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.005787494559548202, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08708058150460311, \"functional effect\": -2.3985, \"times_seen\": 1.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0048205055631517085, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.087138968196328, \"functional effect\": -2.9313, \"times_seen\": 1.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00560715832535853, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08709146721864411, \"functional effect\": -2.4874, \"times_seen\": 2.0}, {\"site\": 1046, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.008783417447007398, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08796453314010841, \"functional effect\": -2.5783, \"times_seen\": 6.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0998705011555504, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08158297034226261, \"functional effect\": -0.8474, \"times_seen\": 91.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01849106392115048, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08631716442840787, \"functional effect\": -0.1566, \"times_seen\": 32.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.01645180307049733, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08843333759040764, \"functional effect\": -2.1339, \"times_seen\": 7.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": -2.0457899708567924, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.02117480326072, \"functional effect\": -1.9149, \"times_seen\": 19.0}, {\"site\": 1047, \"wildtype\": \"M\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.028646206117512302, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08571171059891249, \"functional effect\": -2.3353, \"times_seen\": 2.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.027457590825508027, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08911054265856007, \"functional effect\": -2.1776, \"times_seen\": 2.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0033059090579244817, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08723049805969758, \"functional effect\": -2.77, \"times_seen\": 1.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.009160910971055248, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.0868772011106961, \"functional effect\": -2.9548, \"times_seen\": 2.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004075075927180405, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.0871840038771338, \"functional effect\": -2.9464, \"times_seen\": 1.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.003980785868705248, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08718970213853518, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1048, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.003312171821606281, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.0876315700976757, \"functional effect\": -2.7313, \"times_seen\": 1.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.018596758259210144, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08856491538072667, \"functional effect\": -2.9498, \"times_seen\": 1.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.026613444540379966, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08583256377375127, \"functional effect\": -2.9411, \"times_seen\": 5.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.002167765798909572, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08729934142034175, \"functional effect\": -1.1545, \"times_seen\": 22.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005415069856669603, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08710306383460459, \"functional effect\": -0.6482, \"times_seen\": 1.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.014276021941215106, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08656972125501212, \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 1049, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06139335979658416, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08378808934397239, \"functional effect\": -1.0543, \"times_seen\": 29.0}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.13606666014018576, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 0.09607793850788232, \"functional effect\": -2.4716, \"times_seen\": 2.0}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": 4.977820951378908, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 2.755097352109177, \"functional effect\": -3.0239, \"times_seen\": 4.0}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.16091131017178262, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 0.09774682530762568, \"functional effect\": -2.2702, \"times_seen\": 1.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05385452864467555, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08422707159981455, \"functional effect\": -0.0857, \"times_seen\": 16.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.002680809186831347, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.0872683020212551, \"functional effect\": -1.9005, \"times_seen\": 1.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.023166076968527665, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08884586377654678, \"functional effect\": -1.8457, \"times_seen\": 2.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.07970771781625288, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.09239701561380556, \"functional effect\": -2.3702, \"times_seen\": 11.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.005838446524908205, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08707750611562791, \"functional effect\": -2.4943, \"times_seen\": 1.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00030025333257512, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08741242018543308, \"functional effect\": -1.7888, \"times_seen\": 9.0}, {\"site\": 1052, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03272130192462974, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08943625866598273, \"functional effect\": -1.1067, \"times_seen\": 10.0}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.017187866071926315, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.08847846779046431, \"functional effect\": -2.8479, \"times_seen\": 1.0}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0023335454383519873, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.08728931045644893, \"functional effect\": -2.9022, \"times_seen\": 3.0}, {\"site\": 1053, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.0454623314971563, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.04235922530659895, \"functional effect\": -1.5274, \"times_seen\": 41.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.004128760434279478, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.08718075971044499, \"functional effect\": -2.98, \"times_seen\": 1.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.17886927657546256, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.09897113425608568, \"functional effect\": -2.7923, \"times_seen\": 6.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008886522678325773, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.08689372598480902, \"functional effect\": -2.7854, \"times_seen\": 2.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04911284564782458, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.0904582058469351, \"functional effect\": -0.7767, \"times_seen\": 1.0}, {\"site\": 1054, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0010462563578505404, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.08736723179061294, \"functional effect\": -2.3737, \"times_seen\": 8.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.023602145232315408, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08601190692430194, \"functional effect\": -0.3326, \"times_seen\": 21.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.06698548381449992, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08346394151602825, \"functional effect\": -0.5183, \"times_seen\": 61.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0183499135056696, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08854976324259373, \"functional effect\": -0.5405, \"times_seen\": 16.0}, {\"site\": 1055, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12073185346914346, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08041176978768821, \"functional effect\": -1.0804, \"times_seen\": 52.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0005647841164257232, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08739639382117971, \"functional effect\": -2.1962, \"times_seen\": 2.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.020803343252283675, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08617893040870658, \"functional effect\": -2.5641, \"times_seen\": 5.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.010521300777227351, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.0867953188342818, \"functional effect\": -2.5162, \"times_seen\": 6.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.07308188104135058, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.09197363864247397, \"functional effect\": -2.4709, \"times_seen\": 5.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004319087630665793, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08716925916830182, \"functional effect\": -2.5775, \"times_seen\": 1.0}, {\"site\": 1056, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.00649611703231891, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08782518151290912, \"functional effect\": -2.9473, \"times_seen\": 4.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.013789957705130178, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08659889272468733, \"functional effect\": -0.8753, \"times_seen\": 11.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.04048485802272981, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08991883812865083, \"functional effect\": -0.6008, \"times_seen\": 15.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.010464084896328728, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08679876112039238, \"functional effect\": -0.2763, \"times_seen\": 19.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 1.7230364553782787, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.28863512891613297, \"functional effect\": -2.1423, \"times_seen\": 20.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.011574192407943497, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08673199795001481, \"functional effect\": -2.6312, \"times_seen\": 4.0}, {\"site\": 1057, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.015589065174322216, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.0864909672065905, \"functional effect\": -0.4204, \"times_seen\": 10.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.014404330025930074, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08656202239912526, \"functional effect\": -0.3203, \"times_seen\": 9.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.040074978917681976, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08503540005734786, \"functional effect\": -1.0395, \"times_seen\": 12.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0001316774732986304, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08743859464955782, \"functional effect\": 0.0117, \"times_seen\": 3.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0017557039166755514, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.0873242793785867, \"functional effect\": -0.0322, \"times_seen\": 10.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02312376688430402, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08604043204936401, \"functional effect\": -2.7374, \"times_seen\": 2.0}, {\"site\": 1058, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.006125942755561943, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.08780264975698723, \"functional effect\": -2.5942, \"times_seen\": 1.0}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.7655133011327421, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.14862983500614124, \"functional effect\": -1.2258, \"times_seen\": 14.0}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.006739462374978775, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.08783999659913601, \"functional effect\": -2.8525, \"times_seen\": 4.0}, {\"site\": 1059, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012148131429672027, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.08669750072340987, \"functional effect\": -0.6038, \"times_seen\": 2.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.009716585390219018, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08684374557012303, \"functional effect\": -2.6833, \"times_seen\": 3.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.021430226461256165, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08873902872831667, \"functional effect\": -2.513, \"times_seen\": 10.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.014417883294460797, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08656120920382747, \"functional effect\": -2.5841, \"times_seen\": 9.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.04500553889446349, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.09020104046540364, \"functional effect\": -2.738, \"times_seen\": 6.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.021565502508391093, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08613341509109346, \"functional effect\": -2.7019, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.03289893090004098, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08545942470985096, \"functional effect\": -1.2671, \"times_seen\": 46.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.004291995663890633, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08769110635690286, \"functional effect\": -2.5585, \"times_seen\": 18.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.014222058356632228, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08829676578411104, \"functional effect\": -2.5981, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.056713292692829244, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08406033718161544, \"functional effect\": -1.4099, \"times_seen\": 31.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.019070030911110515, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.0862825314941276, \"functional effect\": -2.6852, \"times_seen\": 4.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.02329919422860689, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08602997042967056, \"functional effect\": -0.7638, \"times_seen\": 22.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.014441630273670323, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.0865597844049201, \"functional effect\": -2.6918, \"times_seen\": 4.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.06166928805134186, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.09124894154065544, \"functional effect\": -2.6696, \"times_seen\": 14.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01163791474394118, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08672816717268172, \"functional effect\": -2.8479, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.011352309958613107, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08812130413343473, \"functional effect\": -2.7412, \"times_seen\": 16.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.040828465864501874, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08499099958940229, \"functional effect\": -2.5558, \"times_seen\": 15.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.00870972351016063, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08796003996102009, \"functional effect\": -2.7268, \"times_seen\": 7.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.07875376397402685, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.09233594009144454, \"functional effect\": -1.8064, \"times_seen\": 58.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.03602500280428272, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08964129798688611, \"functional effect\": -2.3231, \"times_seen\": 5.0}, {\"site\": 1060, \"wildtype\": \"L\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.023786090668589856, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.0888840544472674, \"functional effect\": -3.0762, \"times_seen\": 3.0}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.002691811902254895, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.08759389655905263, \"functional effect\": -3.0111, \"times_seen\": 1.0}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.059100065337032756, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.09108658551922907, \"functional effect\": -2.0417, \"times_seen\": 1.0}, {\"site\": 1061, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007460375385253208, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.08697966550750556, \"functional effect\": -2.1372, \"times_seen\": 3.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.07522197668565452, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.0829887949968342, \"functional effect\": -0.3229, \"times_seen\": 31.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.006955511875843102, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.08785315198399209, \"functional effect\": 0.125, \"times_seen\": 8.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.2149465577409566, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.037664150189036724, \"functional effect\": -0.6764, \"times_seen\": 90.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.8644025006906583, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.15917490927354608, \"functional effect\": 0.4444, \"times_seen\": 47.0}, {\"site\": 1062, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05836358483996622, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.0839642359282548, \"functional effect\": -0.233, \"times_seen\": 22.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.12405757457734008, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.08022661692386295, \"functional effect\": -0.4897, \"times_seen\": 36.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07168394278954388, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.0831925646681998, \"functional effect\": -1.4653, \"times_seen\": 29.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.29836966362431605, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.10751814142877486, \"functional effect\": 0.2891, \"times_seen\": 104.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.09204184447874242, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.0931903378047964, \"functional effect\": -2.9958, \"times_seen\": 4.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.32641934322894106, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.06972708611591222, \"functional effect\": 0.2725, \"times_seen\": 44.0}, {\"site\": 1063, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -2.771485956593967, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.012804514741629467, \"functional effect\": -0.8799, \"times_seen\": 37.0}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.07019731970936519, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.08327833451282678, \"functional effect\": -2.6468, \"times_seen\": 4.0}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.042649273382152235, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.08488380116407764, \"functional effect\": -2.9939, \"times_seen\": 2.0}, {\"site\": 1064, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0028787142088587407, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08725633161155993, \"functional effect\": -2.4287, \"times_seen\": 6.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0066361979933256985, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08702936911927572, \"functional effect\": -2.1319, \"times_seen\": 30.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.15900252993432834, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09761758535697378, \"functional effect\": -1.0246, \"times_seen\": 58.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.01898573796870938, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08858879748934922, \"functional effect\": -2.55, \"times_seen\": 13.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.11949116551177287, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09498039141873098, \"functional effect\": -2.4462, \"times_seen\": 16.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.016597302934505787, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08643054349104559, \"functional effect\": -1.9872, \"times_seen\": 26.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -1.3384825414366268, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.03457324440644618, \"functional effect\": -2.5016, \"times_seen\": 11.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.027397299754526386, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08578594128843213, \"functional effect\": -1.3264, \"times_seen\": 15.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.09480060319910076, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09336870926465052, \"functional effect\": -0.0789, \"times_seen\": 56.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.3445891003026965, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.11101845658464594, \"functional effect\": -1.1811, \"times_seen\": 21.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.003230486892722031, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08762660856684243, \"functional effect\": -0.6599, \"times_seen\": 122.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.01603252695678728, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08840764082305537, \"functional effect\": -1.4082, \"times_seen\": 35.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.09624403340584144, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09346217230010267, \"functional effect\": -1.7039, \"times_seen\": 10.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.01267208501468648, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08666601990640702, \"functional effect\": -2.59, \"times_seen\": 11.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.08607414491841373, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09280565269235991, \"functional effect\": -0.6464, \"times_seen\": 33.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.12034897958408003, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09503688273613678, \"functional effect\": -0.9362, \"times_seen\": 64.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.11371525074355247, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09460089199542553, \"functional effect\": -2.2309, \"times_seen\": 36.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.020856100356855513, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08870372171233865, \"functional effect\": -1.7788, \"times_seen\": 29.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.048016277577909446, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.0845686095523121, \"functional effect\": -2.3901, \"times_seen\": 8.0}, {\"site\": 1065, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006319043547057531, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08704850329851913, \"functional effect\": -2.8595, \"times_seen\": 2.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.017457384274117516, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08637903215888315, \"functional effect\": -2.8035, \"times_seen\": 6.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005699297267114892, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08708590522587549, \"functional effect\": -2.9453, \"times_seen\": 2.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.002073179385712154, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08730506515407353, \"functional effect\": -2.8659, \"times_seen\": 1.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04796129946017287, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.09038603172995899, \"functional effect\": -2.1741, \"times_seen\": 32.0}, {\"site\": 1066, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.009276832294326047, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08799462295702502, \"functional effect\": -1.1377, \"times_seen\": 15.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.030360087096442678, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08929000079863356, \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.005297566345420962, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08775224910792861, \"functional effect\": -0.5238, \"times_seen\": 12.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004701298964379604, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08714616858787713, \"functional effect\": -2.3483, \"times_seen\": 2.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.050945871281265424, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08439705542476733, \"functional effect\": 0.2697, \"times_seen\": 23.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.017072694525697884, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08640206790643831, \"functional effect\": -0.4643, \"times_seen\": 34.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.029513198572934597, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08566021733113795, \"functional effect\": 0.3362, \"times_seen\": 11.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04604137188762196, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08468445482045882, \"functional effect\": -0.3005, \"times_seen\": 52.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.041392298886514405, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.0899754139764605, \"functional effect\": 0.4444, \"times_seen\": 97.0}, {\"site\": 1067, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.03923309739644034, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.089840853494451, \"functional effect\": 0.1886, \"times_seen\": 52.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.03204811380241026, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08939453579277656, \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.020274486658120476, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08866796855574398, \"functional effect\": -0.506, \"times_seen\": 24.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0009449520370867517, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08748789933984052, \"functional effect\": -1.27, \"times_seen\": 45.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.09856490553222158, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.0816568338939413, \"functional effect\": -0.0109, \"times_seen\": 25.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.42244007610425155, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.06523736267678679, \"functional effect\": -0.5261, \"times_seen\": 77.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.7218574363306679, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.1441996714563808, \"functional effect\": -0.2455, \"times_seen\": 77.0}, {\"site\": 1068, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.13599106293581356, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.09607290415685586, \"functional effect\": -1.2601, \"times_seen\": 9.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.02963736809154774, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.08565284506608054, \"functional effect\": -1.382, \"times_seen\": 3.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.044150477855001716, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.08479552078365939, \"functional effect\": 0.4134, \"times_seen\": 9.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.038888690162957894, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.08981940880522085, \"functional effect\": -1.3371, \"times_seen\": 21.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.03404696292212077, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.08539144698212842, \"functional effect\": -1.4297, \"times_seen\": 3.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.010516191072772027, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.0880702479240827, \"functional effect\": -0.3225, \"times_seen\": 1.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.14162501010959977, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.07925563570665398, \"functional effect\": -1.5922, \"times_seen\": 52.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.36683552040841816, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.11274363296386548, \"functional effect\": 0.1158, \"times_seen\": 50.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -2.011789466913311, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.021679764258562412, \"functional effect\": -2.3716, \"times_seen\": 9.0}, {\"site\": 1069, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -4.608458630121822, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.0035840928210394717, \"functional effect\": -1.6824, \"times_seen\": 20.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.012371288730327099, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08818356639533294, \"functional effect\": -0.3758, \"times_seen\": 54.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.006935642872693462, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08701130723243511, \"functional effect\": -0.4496, \"times_seen\": 15.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.8271932666596086, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.04927805347412704, \"functional effect\": -0.0038, \"times_seen\": 87.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07535686757404854, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08298103597039586, \"functional effect\": -0.4858, \"times_seen\": 39.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01785680823232634, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.0863551206056377, \"functional effect\": -0.013, \"times_seen\": 25.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.24185991409260402, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.10338811538766653, \"functional effect\": 0.0736, \"times_seen\": 112.0}, {\"site\": 1070, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06987357865384217, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08329702428465191, \"functional effect\": -0.6264, \"times_seen\": 50.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0561788241850503, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.09090233544266785, \"functional effect\": -0.441, \"times_seen\": 70.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.010892805432851265, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.086772971274451, \"functional effect\": -0.3182, \"times_seen\": 11.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.04296735878142603, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.09007369812500897, \"functional effect\": -0.6686, \"times_seen\": 22.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02141833788975133, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08873829747471725, \"functional effect\": 0.3058, \"times_seen\": 42.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.022057159211408203, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08610406664627757, \"functional effect\": -0.648, \"times_seen\": 52.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0003055842364815995, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08744913539384315, \"functional effect\": 0.4069, \"times_seen\": 65.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04473336831564691, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08476126786447166, \"functional effect\": 0.3442, \"times_seen\": 23.0}, {\"site\": 1071, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0036814073155848268, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08765400091368744, \"functional effect\": -1.2563, \"times_seen\": 20.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.07450257436507568, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08303018781916953, \"functional effect\": 0.1042, \"times_seen\": 27.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00823126713196633, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.0869332010827616, \"functional effect\": -2.9691, \"times_seen\": 1.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.07167365387429432, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08319315797744067, \"functional effect\": -1.3245, \"times_seen\": 29.0}, {\"site\": 1072, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.056005219828738885, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08410160401263916, \"functional effect\": -0.1886, \"times_seen\": 34.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.028216231777775228, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.0891574137453995, \"functional effect\": -1.4501, \"times_seen\": 19.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06475730258699579, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08359294762604097, \"functional effect\": -1.2811, \"times_seen\": 10.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.13583898081813695, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.07957413422620745, \"functional effect\": 0.0389, \"times_seen\": 76.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.006135404204967291, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08705958432871438, \"functional effect\": -0.1396, \"times_seen\": 2.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01113230316479773, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08675856753398872, \"functional effect\": -1.4546, \"times_seen\": 2.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.010244450766720824, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08681197626359367, \"functional effect\": -0.921, \"times_seen\": 66.0}, {\"site\": 1073, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.08166147774292323, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08261919814989445, \"functional effect\": 0.1939, \"times_seen\": 53.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02143405690197947, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08873926433600296, \"functional effect\": -2.176, \"times_seen\": 3.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.008704890193640185, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08690466642367903, \"functional effect\": -1.5999, \"times_seen\": 8.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02217284013808214, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08609716276249854, \"functional effect\": -0.8197, \"times_seen\": 14.0}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.14208423405172363, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.07923041187733944, \"functional effect\": -2.5227, \"times_seen\": 7.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005572083400586113, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08709358461955569, \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.016887965448026242, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08846007721645369, \"functional effect\": -0.7531, \"times_seen\": 20.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.015759355814779986, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08648075872000113, \"functional effect\": -3.0754, \"times_seen\": 3.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.010687265644360858, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08678533464176612, \"functional effect\": -2.0433, \"times_seen\": 2.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.010222804568408364, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08681327880037261, \"functional effect\": -2.4729, \"times_seen\": 8.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.045053705439055035, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08474244949625652, \"functional effect\": -0.6183, \"times_seen\": 53.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.020612190795977516, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08619034959650534, \"functional effect\": -2.7754, \"times_seen\": 6.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01013339717390825, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.0868186590015641, \"functional effect\": -1.9792, \"times_seen\": 3.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.013987348725965222, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08658704498555443, \"functional effect\": -3.0339, \"times_seen\": 2.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01812022240951084, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08633935491304245, \"functional effect\": -2.9199, \"times_seen\": 5.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.01458829270929679, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08655098530102884, \"functional effect\": -2.7906, \"times_seen\": 3.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0094807386144295, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.088007060739986, \"functional effect\": -2.6398, \"times_seen\": 1.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05394151922446242, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.09076147502125627, \"functional effect\": -2.6828, \"times_seen\": 2.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.07501182431330725, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08300088456666535, \"functional effect\": -3.0061, \"times_seen\": 8.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -2.0079308122526007, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.021737826907247244, \"functional effect\": -0.437, \"times_seen\": 72.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 1.200829479975868, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.20097832533281929, \"functional effect\": -0.7051, \"times_seen\": 96.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.017071121895386943, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08640216209029639, \"functional effect\": -2.1939, \"times_seen\": 28.0}, {\"site\": 1075, \"wildtype\": \"A\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.014514688908446642, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08655540109495143, \"functional effect\": -2.8147, \"times_seen\": 3.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01483323136371363, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08653629204864102, \"functional effect\": -1.5482, \"times_seen\": 3.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005162654511401451, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08711830480568991, \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.029265924493553586, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08567490052205089, \"functional effect\": -0.5505, \"times_seen\": 19.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0076960796487688535, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08789826055705402, \"functional effect\": 0.2181, \"times_seen\": 44.0}, {\"site\": 1076, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.05728075150793332, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.09097179297041996, \"functional effect\": -2.3128, \"times_seen\": 1.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0019451559915567847, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08754857472915221, \"functional effect\": -1.1145, \"times_seen\": 5.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.017902101119665035, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08635240956051589, \"functional effect\": -0.4165, \"times_seen\": 27.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.011591646771632137, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08673094863423068, \"functional effect\": -2.092, \"times_seen\": 11.0}, {\"site\": 1077, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0038303431041701824, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08766305029089828, \"functional effect\": -2.1791, \"times_seen\": 5.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.2552128463811934, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.1043494710605331, \"functional effect\": -0.4039, \"times_seen\": 57.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.04179552178869781, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.09000056497304193, \"functional effect\": -2.9388, \"times_seen\": 5.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.034472317643884684, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08536627444028833, \"functional effect\": -0.7406, \"times_seen\": 7.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.029173499472020126, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08921659176357472, \"functional effect\": -0.0659, \"times_seen\": 23.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.028120046366057302, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.0857429758877195, \"functional effect\": -1.4291, \"times_seen\": 10.0}, {\"site\": 1078, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.004554715034818039, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08770707664128927, \"functional effect\": -0.3121, \"times_seen\": 30.0}, {\"site\": 1079, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.02366700552342871, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": 0.08887671794621468, \"functional effect\": -2.469, \"times_seen\": 3.0}, {\"site\": 1079, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01170132239741677, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": 0.08672435548097371, \"functional effect\": -2.5589, \"times_seen\": 2.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.016016379112364428, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.08840665129664822, \"functional effect\": -0.003, \"times_seen\": 6.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.002560513636937756, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.08758592508690054, \"functional effect\": -0.7085, \"times_seen\": 4.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.00022800547029981725, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.0874167977693645, \"functional effect\": -0.1981, \"times_seen\": 2.0}, {\"site\": 1080, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.06989587577390412, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.09177075087397275, \"functional effect\": -0.163, \"times_seen\": 9.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0032415823052949866, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08762728248411916, \"functional effect\": -0.2165, \"times_seen\": 5.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.055724545437054594, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08411796745896881, \"functional effect\": -0.1137, \"times_seen\": 25.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.027387349190279024, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08578653297374325, \"functional effect\": -0.0057, \"times_seen\": 18.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -1.9093941113908608, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.023274407231689855, \"functional effect\": 0.2472, \"times_seen\": 6.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.09288492307372212, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.0932448120614051, \"functional effect\": 0.2612, \"times_seen\": 17.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01573811271998819, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.0864820321232004, \"functional effect\": -0.2983, \"times_seen\": 8.0}, {\"site\": 1081, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0028824019654274374, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08760546908726247, \"functional effect\": -0.239, \"times_seen\": 3.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02704454789614033, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08908503400274724, \"functional effect\": 0.0323, \"times_seen\": 25.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0051497920735128905, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08711908151784872, \"functional effect\": -1.0749, \"times_seen\": 1.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.06280090387941323, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08370638259808841, \"functional effect\": 0.1623, \"times_seen\": 48.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.08128559129292603, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08264072694304131, \"functional effect\": -0.0241, \"times_seen\": 28.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.012247211813121654, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08817598262033964, \"functional effect\": -0.1119, \"times_seen\": 5.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0021217287581719144, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.0873021272256216, \"functional effect\": 0.1736, \"times_seen\": 15.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.013350858862835192, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08824346215854027, \"functional effect\": -0.1385, \"times_seen\": 21.0}, {\"site\": 1082, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.020353190272405966, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08867280580807506, \"functional effect\": -2.2934, \"times_seen\": 4.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.03961118645186429, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08506274132958819, \"functional effect\": -0.3973, \"times_seen\": 24.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.012829012713265886, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08665659341015457, \"functional effect\": -0.2824, \"times_seen\": 6.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02683593980110815, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08581932752799193, \"functional effect\": -0.5523, \"times_seen\": 8.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.04552074402690586, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.0902332581805508, \"functional effect\": -0.7429, \"times_seen\": 15.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.008924462195103403, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08797313339280688, \"functional effect\": -0.4261, \"times_seen\": 13.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.016260136597880857, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.0884215897299542, \"functional effect\": 0.1127, \"times_seen\": 52.0}, {\"site\": 1083, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.004843628383434481, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08713757158616627, \"functional effect\": -0.0806, \"times_seen\": 2.0}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02765788904516042, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.08912291528175442, \"functional effect\": 0.0105, \"times_seen\": 13.0}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.17419715303877303, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.07748630679331638, \"functional effect\": -1.0232, \"times_seen\": 20.0}, {\"site\": 1084, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.00096785492642377, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.08737197978097887, \"functional effect\": -1.8206, \"times_seen\": 15.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.004134185141958305, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.0876815147093089, \"functional effect\": -1.4304, \"times_seen\": 1.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.005564710673621945, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.08776849972606678, \"functional effect\": -0.7507, \"times_seen\": 7.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.29449731501042853, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.10722993813375901, \"functional effect\": -0.1165, \"times_seen\": 7.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.030714983740862463, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.0855888908828801, \"functional effect\": -0.3033, \"times_seen\": 8.0}, {\"site\": 1085, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.021751386844114214, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.0887587852479005, \"functional effect\": 0.2076, \"times_seen\": 64.0}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.006884372584249607, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.08701439948267722, \"functional effect\": -1.8346, \"times_seen\": 2.0}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.011485927836145509, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.08673730440538263, \"functional effect\": -1.3854, \"times_seen\": 3.0}, {\"site\": 1086, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04298638444846523, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.08486396888841145, \"functional effect\": 0.394, \"times_seen\": 21.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.014579192932469037, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08655153122176192, \"functional effect\": -0.1195, \"times_seen\": 2.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.036128878482009956, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08526830968314272, \"functional effect\": -1.4863, \"times_seen\": 9.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.025564136397226985, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08899366689954016, \"functional effect\": -2.0288, \"times_seen\": 1.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.17985155548275647, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.07718320650887874, \"functional effect\": -0.3631, \"times_seen\": 33.0}, {\"site\": 1087, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.02460930973624015, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08893478722617505, \"functional effect\": -0.4244, \"times_seen\": 1.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.018946100869246023, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08628994363371634, \"functional effect\": -1.6448, \"times_seen\": 7.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.00021089364551432106, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08741783462729745, \"functional effect\": -0.0665, \"times_seen\": 38.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.011436263782645707, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08674029034499622, \"functional effect\": -0.3618, \"times_seen\": 5.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.2410615386804813, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.036988505168827054, \"functional effect\": 0.3108, \"times_seen\": 21.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.021392459496133834, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08873670574262549, \"functional effect\": -1.0451, \"times_seen\": 5.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.008641298736121145, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08690849711280259, \"functional effect\": -1.0036, \"times_seen\": 4.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03768442434846817, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08974446482335241, \"functional effect\": 0.2589, \"times_seen\": 12.0}, {\"site\": 1088, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01537356255770487, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08650388776248805, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.014569722026215775, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08655209941123071, \"functional effect\": -0.5347, \"times_seen\": 8.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.07439443380371086, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08303641177322305, \"functional effect\": 0.2621, \"times_seen\": 25.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.001526449449123077, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08752316960812621, \"functional effect\": -1.3051, \"times_seen\": 24.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.004900354637360244, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08772809194249036, \"functional effect\": -1.5301, \"times_seen\": 32.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.029919069477099026, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08563612207963721, \"functional effect\": -0.7884, \"times_seen\": 17.0}, {\"site\": 1089, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03069784717335476, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08558990752775365, \"functional effect\": -0.9278, \"times_seen\": 13.0}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0359874296848347, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.0852766702103391, \"functional effect\": -2.5162, \"times_seen\": 2.0}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.274052762288558, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.03615225839832082, \"functional effect\": -0.8766, \"times_seen\": 26.0}, {\"site\": 1090, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.021145359133643855, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.08615850262005337, \"functional effect\": -1.0177, \"times_seen\": 5.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.036526953704075354, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08524478529448336, \"functional effect\": -1.5209, \"times_seen\": 12.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.01566230641035274, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08838495680117833, \"functional effect\": 0.223, \"times_seen\": 24.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03676831098360861, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08523052536568815, \"functional effect\": -1.4895, \"times_seen\": 9.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.013197315513898739, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.0866344738411404, \"functional effect\": -2.3822, \"times_seen\": 5.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03298383955413101, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08945253550845679, \"functional effect\": -1.3913, \"times_seen\": 6.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.01697319529326811, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08640802705626234, \"functional effect\": -0.105, \"times_seen\": 6.0}, {\"site\": 1091, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.047829387513269005, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": 0.08457956547592198, \"functional effect\": -0.5826, \"times_seen\": 35.0}, {\"site\": 1092, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.9998504833451503, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": 0.1748431074970525, \"functional effect\": -0.2225, \"times_seen\": 25.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.06041005305035295, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08384521678593264, \"functional effect\": 0.3309, \"times_seen\": 13.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.022806733536435347, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08882373699230647, \"functional effect\": -2.2618, \"times_seen\": 1.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.02610478468396032, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08586283162377878, \"functional effect\": -2.2925, \"times_seen\": 2.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.02444730578947574, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08596153412860327, \"functional effect\": 0.3568, \"times_seen\": 79.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.12373570436035695, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08024451775434349, \"functional effect\": -0.4912, \"times_seen\": 22.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.033226269831500226, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.0854400366738313, \"functional effect\": -0.7564, \"times_seen\": 35.0}, {\"site\": 1093, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02551622950909037, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08899071177823008, \"functional effect\": -0.3257, \"times_seen\": 15.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.07565587568097476, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08296383938295028, \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.02985708961926921, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08563980118612582, \"functional effect\": 0.0757, \"times_seen\": 17.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0039511302675237486, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08719149440199746, \"functional effect\": -1.405, \"times_seen\": 1.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.009815832946939657, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08802750448699989, \"functional effect\": -0.6398, \"times_seen\": 5.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.28037007512862255, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.10618503938354175, \"functional effect\": 0.4231, \"times_seen\": 71.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01313032235840616, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08663849690309759, \"functional effect\": 0.158, \"times_seen\": 2.0}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1094, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.023841478168541052, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08599763933880923, \"functional effect\": -2.1066, \"times_seen\": 8.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.005417230051700057, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08710293341240209, \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.007527944735460387, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08788801729367676, \"functional effect\": -0.5034, \"times_seen\": 14.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0055934797867407526, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08709229295770282, \"functional effect\": -0.5287, \"times_seen\": 1.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.013142577081957091, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08663776097049299, \"functional effect\": -1.0252, \"times_seen\": 3.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08430814682930449, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08246776959459715, \"functional effect\": -0.536, \"times_seen\": 24.0}, {\"site\": 1095, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.009013570794974118, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08688607419573217, \"functional effect\": -0.0463, \"times_seen\": 12.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.00047938207433872396, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08740156750737903, \"functional effect\": 0.2974, \"times_seen\": 1.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0016859303003280996, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08753284527811986, \"functional effect\": -0.8839, \"times_seen\": 27.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.05479605084037694, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08417212181201655, \"functional effect\": -0.263, \"times_seen\": 140.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.026276677914405123, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08585260190796375, \"functional effect\": -0.1589, \"times_seen\": 6.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.022606500990926686, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08607128663694144, \"functional effect\": -0.217, \"times_seen\": 72.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0008392310455655826, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08737976980158826, \"functional effect\": -0.2863, \"times_seen\": 13.0}, {\"site\": 1096, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.01445986624161581, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08831132145749054, \"functional effect\": -0.5929, \"times_seen\": 28.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.4411263266950059, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.0643978360013053, \"functional effect\": -0.0827, \"times_seen\": 32.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0820688647695119, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.09254835844670972, \"functional effect\": -0.0143, \"times_seen\": 71.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.019790190215373465, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.08623947203944951, \"functional effect\": 0.0987, \"times_seen\": 12.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.06320463172702435, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.08368296124529154, \"functional effect\": 0.1204, \"times_seen\": 4.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0626695660994816, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.08371400327368418, \"functional effect\": -0.0231, \"times_seen\": 39.0}, {\"site\": 1097, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.2543366175913902, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.10428611307613689, \"functional effect\": 0.0306, \"times_seen\": 83.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01760564425502923, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.086370155788424, \"functional effect\": -0.1584, \"times_seen\": 19.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.019991438965724403, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08622744290298302, \"functional effect\": -0.1489, \"times_seen\": 17.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0059005433962548955, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08778893298766034, \"functional effect\": -0.0334, \"times_seen\": 44.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.5393949570390008, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.12706840879676934, \"functional effect\": -0.1925, \"times_seen\": 83.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.013437640200449618, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.0882487703600582, \"functional effect\": -0.0986, \"times_seen\": 24.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.008693541785503207, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08795905337887705, \"functional effect\": -0.1924, \"times_seen\": 1.0}, {\"site\": 1098, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06536080015176074, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08355798695256654, \"functional effect\": 0.0633, \"times_seen\": 127.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.013461741445065931, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.0866185964023886, \"functional effect\": -1.9349, \"times_seen\": 3.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00525377329755109, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.0871128026979783, \"functional effect\": -2.729, \"times_seen\": 6.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.008717834800501915, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08690388667351517, \"functional effect\": 0.0646, \"times_seen\": 16.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.07082760927572347, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.0918300381784017, \"functional effect\": -1.6568, \"times_seen\": 28.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.026000057402124688, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08902056105885588, \"functional effect\": -2.9385, \"times_seen\": 2.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.017320339345035133, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08638723789209014, \"functional effect\": -2.2473, \"times_seen\": 6.0}, {\"site\": 1099, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.048397621009311234, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08454625872903755, \"functional effect\": -0.6281, \"times_seen\": 12.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.002161466257002005, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08756170229574145, \"functional effect\": 0.0246, \"times_seen\": 1.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0275960388800186, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08911909455130577, \"functional effect\": -0.1738, \"times_seen\": 52.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.03315389307138278, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08544432311551273, \"functional effect\": 0.2814, \"times_seen\": 49.0}, {\"site\": 1100, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012950132671731835, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.0866493185515561, \"functional effect\": 0.4077, \"times_seen\": 5.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -1.5247989610279407, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.030384584741870852, \"functional effect\": -1.4398, \"times_seen\": 3.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.01150936459999428, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.08813089771542612, \"functional effect\": -0.0063, \"times_seen\": 5.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.3714845487940261, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.06758269992876814, \"functional effect\": -0.1818, \"times_seen\": 19.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.11570821550628034, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.08069226132816525, \"functional effect\": -0.4747, \"times_seen\": 29.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.053011362723071095, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.09070297674928786, \"functional effect\": -0.0126, \"times_seen\": 8.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0003138147762272631, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.08744963429043409, \"functional effect\": -1.5585, \"times_seen\": 3.0}, {\"site\": 1101, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0038081462863449682, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": 0.08720013628711977, \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 1102, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.00015820338191821118, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": 0.08744020234170928, \"functional effect\": -3.1318, \"times_seen\": 1.0}, {\"site\": 1102, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.007773079721560151, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08696081469681284, \"functional effect\": -2.9491, \"times_seen\": 1.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.3796959853927861, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.06719912979432169, \"functional effect\": -2.739, \"times_seen\": 4.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.02438681993541915, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08596513819298078, \"functional effect\": -2.4537, \"times_seen\": 8.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.011701867739951221, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08672432269894456, \"functional effect\": -2.9677, \"times_seen\": 2.0}, {\"site\": 1103, \"wildtype\": \"Q\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.005631002682229897, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08709002781336089, \"functional effect\": -2.1603, \"times_seen\": 1.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.052257006095872104, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.0843203894301234, \"functional effect\": -1.9585, \"times_seen\": 13.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.05957613327577871, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08389369577431562, \"functional effect\": 0.0633, \"times_seen\": 59.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.034922528316083355, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08533963900409489, \"functional effect\": 0.0679, \"times_seen\": 15.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"M\", \"log2 fold change IC90\": 1.1939085903675615, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.2000165019632445, \"functional effect\": 0.0667, \"times_seen\": 68.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.07849912858865021, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.09231964425468514, \"functional effect\": -1.0549, \"times_seen\": 8.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.4589794353163854, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.06360583415758113, \"functional effect\": -1.0861, \"times_seen\": 35.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.018589421704766847, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08631127983371566, \"functional effect\": -1.7845, \"times_seen\": 5.0}, {\"site\": 1104, \"wildtype\": \"R\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.002742810479951675, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08726455165741809, \"functional effect\": -1.3463, \"times_seen\": 1.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0002788679669469453, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08744751599890979, \"functional effect\": -0.8893, \"times_seen\": 8.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 1.7421526210038696, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.2924850859172559, \"functional effect\": 0.0578, \"times_seen\": 22.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.009128104527857093, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.0879855520384993, \"functional effect\": 0.1833, \"times_seen\": 2.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.00591760366531202, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08707272851738987, \"functional effect\": -2.3399, \"times_seen\": 20.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.11891119015110233, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.09494221618826264, \"functional effect\": -2.3165, \"times_seen\": 10.0}, {\"site\": 1105, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01167162549155245, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08672614066180191, \"functional effect\": -1.0527, \"times_seen\": 15.0}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.06471236193020163, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.08359555162784016, \"functional effect\": -1.3553, \"times_seen\": 10.0}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.5329503012713571, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.06042678705994287, \"functional effect\": -0.8859, \"times_seen\": 26.0}, {\"site\": 1106, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009313925442775737, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.08686798726874218, \"functional effect\": 0.2652, \"times_seen\": 18.0}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.018093087762751984, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.08634097882513934, \"functional effect\": -2.561, \"times_seen\": 2.0}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.01379089806646262, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.08827038157269958, \"functional effect\": 0.066, \"times_seen\": 30.0}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.10784347223022059, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.0811333502981081, \"functional effect\": -1.6806, \"times_seen\": 9.0}, {\"site\": 1107, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.002136890491652641, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.0875602107279049, \"functional effect\": -1.2492, \"times_seen\": 11.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.002857859545430262, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08760397879869297, \"functional effect\": -1.7751, \"times_seen\": 12.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.011811472880249765, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08814935474279822, \"functional effect\": -2.3871, \"times_seen\": 9.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.20860912000152299, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.10103250765931342, \"functional effect\": -1.8824, \"times_seen\": 41.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016729822050611923, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08642260475633154, \"functional effect\": -0.0614, \"times_seen\": 12.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03241044461607591, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.089416989923216, \"functional effect\": -1.9665, \"times_seen\": 4.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00036194359376966434, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08740868247261852, \"functional effect\": -2.4665, \"times_seen\": 2.0}, {\"site\": 1108, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0003656971664912767, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08745277922232123, \"functional effect\": -2.7096, \"times_seen\": 1.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.027010422083234613, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.08580894900291168, \"functional effect\": -2.4076, \"times_seen\": 11.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.013363395165740448, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.08824422895370214, \"functional effect\": -0.7292, \"times_seen\": 43.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.17123480722930942, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.09844878104498496, \"functional effect\": -0.9911, \"times_seen\": 22.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.020823542962889737, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.08617772379385133, \"functional effect\": -1.7155, \"times_seen\": 10.0}, {\"site\": 1109, \"wildtype\": \"P\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04017032603932046, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.089899236433969, \"functional effect\": -1.9212, \"times_seen\": 7.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.008509680346598585, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.08794784432416886, \"functional effect\": -1.6966, \"times_seen\": 2.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.03744465598909211, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.0897295510026881, \"functional effect\": -0.8441, \"times_seen\": 15.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.01995503915981688, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.086229618485273, \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.6548612370440776, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.05553038117768208, \"functional effect\": 0.3841, \"times_seen\": 26.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.7007594990936604, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.05379153047466983, \"functional effect\": 0.4138, \"times_seen\": 48.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.6905252406133716, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.1411017305285715, \"functional effect\": -0.2198, \"times_seen\": 13.0}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1110, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.08039156626152066, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.08269195452295962, \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.014066285450600981, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08658230752507122, \"functional effect\": -0.0523, \"times_seen\": 13.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.035543119994902936, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08961136138495858, \"functional effect\": -0.1349, \"times_seen\": 25.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.02873300429075202, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08570655400247279, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.005675000876660855, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.0877752096511692, \"functional effect\": 0.2317, \"times_seen\": 9.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.018257714402760243, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08633112697573089, \"functional effect\": 0.059, \"times_seen\": 7.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0028876444593114578, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08760578743033383, \"functional effect\": 0.1919, \"times_seen\": 16.0}, {\"site\": 1111, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -2.781824473774452, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.012713084121227243, \"functional effect\": 0.1682, \"times_seen\": 31.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.02024538554449262, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08621226628116174, \"functional effect\": -1.0514, \"times_seen\": 8.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014550585702217272, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08655324747090717, \"functional effect\": -1.0997, \"times_seen\": 11.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03253217230212692, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08942453481813374, \"functional effect\": -1.5368, \"times_seen\": 1.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.005592930270459571, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08709232613078563, \"functional effect\": -1.4465, \"times_seen\": 1.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.059623701230027915, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.083890929711093, \"functional effect\": -1.0783, \"times_seen\": 40.0}, {\"site\": 1112, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.4124529509041654, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.06569053818485235, \"functional effect\": 0.0418, \"times_seen\": 50.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.050136179213915624, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08444443536587394, \"functional effect\": 0.1899, \"times_seen\": 25.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.09719424717831615, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08173445030123618, \"functional effect\": -1.9701, \"times_seen\": 23.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.034727822287868526, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08535115721341562, \"functional effect\": -0.2024, \"times_seen\": 67.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -1.6867557877392847, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.027158103712789226, \"functional effect\": 0.2663, \"times_seen\": 25.0}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1113, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0736470386051603, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08307944033573067, \"functional effect\": -1.6437, \"times_seen\": 8.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"*\", \"log2 fold change IC90\": 3.14272246704908, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.7721777093697112, \"functional effect\": -2.7794, \"times_seen\": 7.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05610732047542395, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09089783019870327, \"functional effect\": -0.4808, \"times_seen\": 123.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.034749251940845056, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08534988942497508, \"functional effect\": -0.3026, \"times_seen\": 56.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.12445870990175666, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08020431334929484, \"functional effect\": -0.5538, \"times_seen\": 43.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.06150568303657901, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09123859428253288, \"functional effect\": -0.3872, \"times_seen\": 45.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0027109625673000784, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08726647806904077, \"functional effect\": -0.7441, \"times_seen\": 46.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.5970531266355278, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.1322496191647787, \"functional effect\": -0.8119, \"times_seen\": 122.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06871571735227883, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08336390266919452, \"functional effect\": -1.1124, \"times_seen\": 33.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.018736295580186423, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08857348178480469, \"functional effect\": 0.0388, \"times_seen\": 86.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.6011873398915826, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.265258279218565, \"functional effect\": 0.2293, \"times_seen\": 20.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.034097247512372524, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08952159764863128, \"functional effect\": 0.0931, \"times_seen\": 127.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.059949011447252676, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09114020070209584, \"functional effect\": -0.1527, \"times_seen\": 39.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0672532086986725, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08344845432003484, \"functional effect\": 0.1167, \"times_seen\": 48.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.08671179579046445, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08233048588157395, \"functional effect\": -0.5241, \"times_seen\": 67.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.06906118880312945, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09171767126025311, \"functional effect\": -0.4067, \"times_seen\": 42.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.12226942840346346, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09516347567139345, \"functional effect\": 0.2972, \"times_seen\": 175.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.010275117910354712, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08805553268710851, \"functional effect\": -0.4777, \"times_seen\": 146.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.014030150244828704, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08658447618067218, \"functional effect\": 0.284, \"times_seen\": 92.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.8106022342562484, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.04984802348981407, \"functional effect\": -1.7711, \"times_seen\": 18.0}, {\"site\": 1114, \"wildtype\": \"T\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.7524071209005722, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.14728572006295954, \"functional effect\": -0.4969, \"times_seen\": 43.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.009812947602989645, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08683794519251063, \"functional effect\": -2.9791, \"times_seen\": 2.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.3581355401526239, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.11206579336923594, \"functional effect\": -0.4849, \"times_seen\": 76.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.12817316297517556, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.07999807990203175, \"functional effect\": -0.8215, \"times_seen\": 31.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -2.9707890583034926, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.011152363403669908, \"functional effect\": 0.1149, \"times_seen\": 53.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.07356527045884242, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.09200446049422378, \"functional effect\": 0.2446, \"times_seen\": 33.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07054375684926324, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08325833912676409, \"functional effect\": 0.0924, \"times_seen\": 95.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 1.127797090081784, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.19105758465251108, \"functional effect\": 0.3279, \"times_seen\": 30.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05357032038017904, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.09073812551229049, \"functional effect\": 0.4012, \"times_seen\": 24.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.019226930704310047, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08627314837791339, \"functional effect\": -0.4248, \"times_seen\": 9.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.5188904180195351, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.12527520158329175, \"functional effect\": 0.317, \"times_seen\": 73.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": 1.342553035421315, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.22172377512639213, \"functional effect\": 0.2603, \"times_seen\": 28.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.046114860056434684, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08468014126365281, \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.5351191963970798, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.06033601188250043, \"functional effect\": -1.2134, \"times_seen\": 22.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.12007839075927722, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.09501905949129091, \"functional effect\": 0.3173, \"times_seen\": 19.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0019909668985527086, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08755135476455714, \"functional effect\": 0.2213, \"times_seen\": 77.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07044784921747047, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08326387416731645, \"functional effect\": 0.0417, \"times_seen\": 71.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00024393113833774474, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08741583279535486, \"functional effect\": 0.3475, \"times_seen\": 41.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -1.2534922517464473, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.03667116969873026, \"functional effect\": 0.3064, \"times_seen\": 92.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.025561552028034364, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08589516851787164, \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1115, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.6374978753111542, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.13600958410125477, \"functional effect\": 0.3516, \"times_seen\": 54.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0093017858137997, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08799614496581064, \"functional effect\": -1.0119, \"times_seen\": 5.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.013682347164101253, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08826374020440472, \"functional effect\": -0.995, \"times_seen\": 2.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0009479786259086312, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08737318353065605, \"functional effect\": -2.0861, \"times_seen\": 2.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.015347720500792486, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08836568617918576, \"functional effect\": -1.3586, \"times_seen\": 3.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.015130366660149773, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.0865184709996047, \"functional effect\": -1.6105, \"times_seen\": 3.0}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1116, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.020105560642155147, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08622062231313844, \"functional effect\": -0.8817, \"times_seen\": 3.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0746085567953451, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.09207101767278367, \"functional effect\": -0.5789, \"times_seen\": 14.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.02509109192284586, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08896449159900587, \"functional effect\": -1.8992, \"times_seen\": 1.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0009455123573131819, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.0873733328941159, \"functional effect\": -1.2336, \"times_seen\": 19.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0024098625726290835, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08728469306078075, \"functional effect\": -1.2726, \"times_seen\": 2.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0358735320615336, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08963188690496098, \"functional effect\": -0.4278, \"times_seen\": 18.0}, {\"site\": 1117, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.009041210937648191, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08688440958858094, \"functional effect\": -1.7205, \"times_seen\": 2.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.008593841369083297, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08691135600963579, \"functional effect\": -1.0324, \"times_seen\": 2.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.011724572048469831, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08814404522046146, \"functional effect\": -0.7748, \"times_seen\": 20.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.005264771170024529, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08711213862704437, \"functional effect\": -0.6682, \"times_seen\": 1.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.024020150677393663, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08889847599144998, \"functional effect\": -1.1454, \"times_seen\": 4.0}, {\"site\": 1118, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012505960515574534, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08667599996296016, \"functional effect\": 0.4125, \"times_seen\": 4.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.024646902003036136, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08893710462778254, \"functional effect\": 0.0042, \"times_seen\": 2.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.3480994491692823, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.06868709582957928, \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01148788291758976, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08673718686260702, \"functional effect\": -0.4705, \"times_seen\": 2.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.03819525465130666, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08977624722231507, \"functional effect\": -0.004, \"times_seen\": 13.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.024917316132233542, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08593353359602528, \"functional effect\": -0.163, \"times_seen\": 23.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.032747984194948475, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08546836665051057, \"functional effect\": -0.4456, \"times_seen\": 34.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.045567985757783556, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.0847122465733546, \"functional effect\": -0.1848, \"times_seen\": 20.0}, {\"site\": 1119, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.02950707214482063, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08923722235902144, \"functional effect\": 0.2764, \"times_seen\": 11.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.010844512339643593, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08809029278803888, \"functional effect\": -1.8543, \"times_seen\": 5.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.002917777831946388, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08725396901779789, \"functional effect\": -3.0152, \"times_seen\": 1.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04799809921447456, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08456967514730025, \"functional effect\": -1.1837, \"times_seen\": 16.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.00329277298990481, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08723129231693152, \"functional effect\": -2.4402, \"times_seen\": 1.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04585738435599205, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08469525535482604, \"functional effect\": -0.0177, \"times_seen\": 17.0}, {\"site\": 1120, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.016711389004734616, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08844925094373933, \"functional effect\": -1.2961, \"times_seen\": 2.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.07477357711016454, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08301459249588035, \"functional effect\": 0.0116, \"times_seen\": 22.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -1.1239427346968678, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.04011650164605463, \"functional effect\": -0.3083, \"times_seen\": 52.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.23104763288064173, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.1026161692149142, \"functional effect\": -0.0186, \"times_seen\": 50.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03905528979561267, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.0850955238674099, \"functional effect\": -0.2825, \"times_seen\": 17.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.02758263385354696, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08577492160755464, \"functional effect\": 0.1842, \"times_seen\": 71.0}, {\"site\": 1121, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.012903746654351757, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08665210457444956, \"functional effect\": -0.8127, \"times_seen\": 16.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.007638670020694345, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.08789476286287567, \"functional effect\": -0.5036, \"times_seen\": 57.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 1.2766207539442354, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.21181888128116821, \"functional effect\": -0.4432, \"times_seen\": 21.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.2871097646076256, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.07165308256235378, \"functional effect\": -0.393, \"times_seen\": 79.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.326283413540409, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.21923738848172486, \"functional effect\": -0.5408, \"times_seen\": 19.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.961848995844677, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.044886746818962896, \"functional effect\": -1.063, \"times_seen\": 19.0}, {\"site\": 1122, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01934498648464496, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.08626608893232358, \"functional effect\": -1.0489, \"times_seen\": 28.0}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0015622316816979124, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.08733599076311972, \"functional effect\": -0.724, \"times_seen\": 1.0}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0667502857800224, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.08347754948907776, \"functional effect\": -2.2172, \"times_seen\": 4.0}, {\"site\": 1123, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005958418479649441, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.08707026520610264, \"functional effect\": -2.8921, \"times_seen\": 1.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05187860631086595, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.0906317877242899, \"functional effect\": -0.1624, \"times_seen\": 11.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.08440680349397432, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.09269845794749677, \"functional effect\": 0.008, \"times_seen\": 34.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.105482884809032, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.08126621215315527, \"functional effect\": 0.1577, \"times_seen\": 65.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.6375710026233143, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.0561998988359415, \"functional effect\": 0.02, \"times_seen\": 6.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.19844479880580207, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.07619486309066774, \"functional effect\": -0.24, \"times_seen\": 62.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.011507952529666724, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.08673598025307727, \"functional effect\": -1.2044, \"times_seen\": 17.0}, {\"site\": 1124, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.08145190586726553, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.09250878922046935, \"functional effect\": -0.3369, \"times_seen\": 58.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.041798426673506674, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08493387716919187, \"functional effect\": -0.1722, \"times_seen\": 10.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.033756554933895455, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08540863762442842, \"functional effect\": 0.2539, \"times_seen\": 37.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.14184211473139033, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.0792437097834975, \"functional effect\": 0.2408, \"times_seen\": 80.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.013979947558084382, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08828194920389822, \"functional effect\": 0.3979, \"times_seen\": 29.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.0364141376434755, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08525145153829498, \"functional effect\": 0.3325, \"times_seen\": 13.0}, {\"site\": 1125, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.00538760883189564, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.08775772613325926, \"functional effect\": -1.7693, \"times_seen\": 2.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0663329998096857, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.08350169807727077, \"functional effect\": -0.1637, \"times_seen\": 40.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.006335547739559375, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.08781540727639574, \"functional effect\": -2.1342, \"times_seen\": 13.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.4116076886535274, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.032864518483244114, \"functional effect\": -2.6109, \"times_seen\": 3.0}, {\"site\": 1126, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0058848056281760154, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.0870747080397176, \"functional effect\": -0.7439, \"times_seen\": 25.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.7835851694508706, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.15050335113735136, \"functional effect\": -0.1114, \"times_seen\": 63.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.011103016842562353, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.08810607836777992, \"functional effect\": -1.8813, \"times_seen\": 1.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0038917814724633293, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.08766678357430151, \"functional effect\": -1.3624, \"times_seen\": 1.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.016807761363300134, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.08641793603821402, \"functional effect\": -1.3744, \"times_seen\": 21.0}, {\"site\": 1127, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.9025836288252277, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.1634437341124265, \"functional effect\": -1.21, \"times_seen\": 45.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.18184453532114395, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.07707665705097441, \"functional effect\": -1.6676, \"times_seen\": 30.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.01106891972145647, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08676237927340245, \"functional effect\": -0.4444, \"times_seen\": 26.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0018581414617034062, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08731807919976994, \"functional effect\": -1.1128, \"times_seen\": 15.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0050487627921640375, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08712518252057933, \"functional effect\": -2.0817, \"times_seen\": 1.0}, {\"site\": 1128, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0037719765541470336, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08720232250459818, \"functional effect\": -1.5422, \"times_seen\": 2.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.036272789529254584, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08525980446243583, \"functional effect\": -1.7658, \"times_seen\": 11.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.014492735676918847, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08655671820297753, \"functional effect\": -0.4432, \"times_seen\": 16.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.003911523187858101, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08719388814965134, \"functional effect\": -1.5141, \"times_seen\": 1.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.042040519440745945, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.09001585011566421, \"functional effect\": -1.5754, \"times_seen\": 10.0}, {\"site\": 1129, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.15904081694940833, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.09762017601920721, \"functional effect\": -1.005, \"times_seen\": 27.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.038997349765388135, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.08509894145469758, \"functional effect\": -0.0239, \"times_seen\": 24.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.39525785653759016, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.11498680337918718, \"functional effect\": -0.8393, \"times_seen\": 37.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.004402472282474019, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.08716422111932534, \"functional effect\": 0.0819, \"times_seen\": 20.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.9652717817415413, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.044780379491603454, \"functional effect\": -0.4561, \"times_seen\": 48.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.03396035099238529, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.08539657359572805, \"functional effect\": -0.2285, \"times_seen\": 22.0}, {\"site\": 1130, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.03719179126550446, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.0852055109661972, \"functional effect\": 0.1632, \"times_seen\": 23.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.03352103761417552, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08948585001697616, \"functional effect\": 0.2539, \"times_seen\": 18.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01579393214998217, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08647868610466287, \"functional effect\": -0.4037, \"times_seen\": 1.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.02632547832225865, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08904064321033124, \"functional effect\": 0.3876, \"times_seen\": 8.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.029197718126194833, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08567895107446041, \"functional effect\": 0.1915, \"times_seen\": 19.0}, {\"site\": 1131, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05557192506852145, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08412686663302542, \"functional effect\": 0.0579, \"times_seen\": 26.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.09871270097478288, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.0816484690701847, \"functional effect\": -0.2686, \"times_seen\": 54.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.013139027214118781, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08663797414997369, \"functional effect\": 0.3392, \"times_seen\": 1.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.2595724959023706, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.10466527943918612, \"functional effect\": 0.3287, \"times_seen\": 47.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.1360365125054586, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.07956323979839458, \"functional effect\": 0.4444, \"times_seen\": 34.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.004091627378026674, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08718300365641059, \"functional effect\": 0.1278, \"times_seen\": 29.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1072811382594103, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08116498063617263, \"functional effect\": 0.0169, \"times_seen\": 30.0}, {\"site\": 1132, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006769095362859972, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08702135256608687, \"functional effect\": 0.4444, \"times_seen\": 40.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.06471666381290145, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.08359530235983065, \"functional effect\": 0.2773, \"times_seen\": 28.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05874961395007446, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.09106446196397198, \"functional effect\": 0.3854, \"times_seen\": 73.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.04936747700116579, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.08448944135747052, \"functional effect\": 0.1615, \"times_seen\": 30.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01600391416554285, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.08646610018258234, \"functional effect\": 0.1291, \"times_seen\": 23.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.13122357423440673, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.07982911193927007, \"functional effect\": 0.3655, \"times_seen\": 28.0}, {\"site\": 1133, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0062899202549195725, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.0870502605407, \"functional effect\": -0.6368, \"times_seen\": 1.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.011268055546758953, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08675040425085317, \"functional effect\": -0.3921, \"times_seen\": 26.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.006081043420651511, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08706286479777822, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.11031654939987293, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08099439012154566, \"functional effect\": 0.1507, \"times_seen\": 32.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.029220603527162232, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08567759196422416, \"functional effect\": -0.5631, \"times_seen\": 11.0}, {\"site\": 1134, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.05958416111741968, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.09111715471732422, \"functional effect\": -1.7593, \"times_seen\": 2.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.05333134940796514, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.09072309670739244, \"functional effect\": -0.6748, \"times_seen\": 1.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.05513630206315919, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.09083667120967645, \"functional effect\": 0.2701, \"times_seen\": 31.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.14113690085168132, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.09641619106308669, \"functional effect\": -0.3486, \"times_seen\": 28.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.017020843577866273, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.08640517328179237, \"functional effect\": 0.4337, \"times_seen\": 16.0}, {\"site\": 1135, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.02548492835383755, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08589973065886715, \"functional effect\": -1.913, \"times_seen\": 14.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -2.2371722955207205, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.018544176985458054, \"functional effect\": -2.1192, \"times_seen\": 15.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.03500258070782541, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08957779269104962, \"functional effect\": -1.0282, \"times_seen\": 26.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.13146961213207184, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.09577228003751913, \"functional effect\": -0.2512, \"times_seen\": 63.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.005438896079541438, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08776084594174836, \"functional effect\": -1.4491, \"times_seen\": 12.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.3551667926450436, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.06835144053111046, \"functional effect\": 0.3553, \"times_seen\": 87.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.003686176216852225, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08765429065889005, \"functional effect\": -1.6317, \"times_seen\": 9.0}, {\"site\": 1136, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.020352620454937728, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08620585839812805, \"functional effect\": 0.2, \"times_seen\": 60.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.029428483357514867, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.08923236141898938, \"functional effect\": 0.4051, \"times_seen\": 17.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.010781766924304235, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.08808646166527341, \"functional effect\": 0.4109, \"times_seen\": 3.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02365165971552547, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.08887577257817204, \"functional effect\": 0.2334, \"times_seen\": 5.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.4440786270277617, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.11894454165523846, \"functional effect\": 0.397, \"times_seen\": 21.0}, {\"site\": 1137, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.044150362126818624, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.09014758843686448, \"functional effect\": 0.3651, \"times_seen\": 9.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.03688694254671334, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08969487028099758, \"functional effect\": -0.4315, \"times_seen\": 83.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.031965686924342145, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08938942847501309, \"functional effect\": 0.169, \"times_seen\": 1.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.010789209512997375, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08808691608770926, \"functional effect\": -0.965, \"times_seen\": 4.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.006963914358037891, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08700960214943086, \"functional effect\": -2.5233, \"times_seen\": 2.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0029693665375516787, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08725084899678612, \"functional effect\": 0.1736, \"times_seen\": 1.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.08704596805741166, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.09286818916884668, \"functional effect\": -0.6613, \"times_seen\": 17.0}, {\"site\": 1138, \"wildtype\": \"L\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.01811728986611841, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08633953041386204, \"functional effect\": -0.1245, \"times_seen\": 20.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.017025587833821628, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.08640488914164336, \"functional effect\": -2.2672, \"times_seen\": 1.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.011023014624655117, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.08676514000846562, \"functional effect\": -0.0954, \"times_seen\": 2.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.5992851580137877, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.028855640973315545, \"functional effect\": -0.777, \"times_seen\": 41.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.01450256326451619, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.08831393509807628, \"functional effect\": -0.888, \"times_seen\": 18.0}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1139, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.22925087102314162, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.0745851111469811, \"functional effect\": 0.397, \"times_seen\": 20.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.008005896017865537, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.08791713858977813, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.057253884349262804, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.08402884486837031, \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.18948904071696357, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.09970235464800059, \"functional effect\": 0.394, \"times_seen\": 78.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.0417019478072824, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.17998945535395866, \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 1140, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.020955803160362333, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.08870985212458216, \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.016964720334671286, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08640853465251928, \"functional effect\": -1.4739, \"times_seen\": 3.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.044686825058352614, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08476400241960924, \"functional effect\": 0.2804, \"times_seen\": 33.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 1.2395309695944987, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.2064427009158655, \"functional effect\": -0.8182, \"times_seen\": 55.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.05976938340451101, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.09112885366321453, \"functional effect\": -0.2457, \"times_seen\": 1.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.031694681025116626, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08553078938712072, \"functional effect\": 0.4317, \"times_seen\": 107.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.6674146503939691, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.1388594239489264, \"functional effect\": 0.4266, \"times_seen\": 30.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.04404761798222891, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.09014116864141486, \"functional effect\": 0.312, \"times_seen\": 20.0}, {\"site\": 1141, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.0280376443772511, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08574787338394625, \"functional effect\": 0.3085, \"times_seen\": 51.0}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.046388313199666055, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.09028753655102856, \"functional effect\": -0.6534, \"times_seen\": 6.0}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.011146577815084631, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.08675770911134985, \"functional effect\": -2.2462, \"times_seen\": 1.0}, {\"site\": 1142, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.00493926427469719, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.087131795449922, \"functional effect\": -1.3835, \"times_seen\": 2.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.03866898240611131, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.08511831276618283, \"functional effect\": 0.0804, \"times_seen\": 16.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.06625813558403061, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.0915396433924058, \"functional effect\": -0.0953, \"times_seen\": 83.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 1.5796464441905507, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.2613271259801338, \"functional effect\": -1.1339, \"times_seen\": 18.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.06892184158415054, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.09170881284953447, \"functional effect\": -0.3235, \"times_seen\": 50.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.07366628743332289, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.09201090283814517, \"functional effect\": -0.2148, \"times_seen\": 67.0}, {\"site\": 1143, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0428194739559715, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.08487378766913338, \"functional effect\": -1.1626, \"times_seen\": 49.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.050503722200041554, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08442292492473231, \"functional effect\": 0.4273, \"times_seen\": 22.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009192822432185523, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08687527946565927, \"functional effect\": -1.1498, \"times_seen\": 4.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.4780604156805306, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.12177946304719846, \"functional effect\": -0.5645, \"times_seen\": 34.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.06149520885364897, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.09123793187902374, \"functional effect\": -2.038, \"times_seen\": 9.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.01573276482675361, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.0883892734557619, \"functional effect\": -0.2766, \"times_seen\": 18.0}, {\"site\": 1144, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.001928768988649734, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08731380462415679, \"functional effect\": -1.213, \"times_seen\": 3.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.009059441469640836, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08688331168572824, \"functional effect\": -0.392, \"times_seen\": 3.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.04123749331546915, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08496690667761699, \"functional effect\": -0.3991, \"times_seen\": 27.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.015858397296749482, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08839697088726843, \"functional effect\": -0.2699, \"times_seen\": 2.0}, {\"site\": 1145, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006833499290496097, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08701746789771293, \"functional effect\": 0.1984, \"times_seen\": 1.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.012678646786378232, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08666562572653762, \"functional effect\": -1.6481, \"times_seen\": 3.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.2072012901865218, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.07573379617302232, \"functional effect\": -0.5776, \"times_seen\": 78.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.03656834975376198, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08967506499755236, \"functional effect\": -1.8489, \"times_seen\": 25.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004869169653381219, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08713602892851892, \"functional effect\": -0.9531, \"times_seen\": 1.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.015169598228599325, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08651611831309025, \"functional effect\": -0.0919, \"times_seen\": 57.0}, {\"site\": 1146, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0034211265593948738, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08722353187596843, \"functional effect\": -2.3638, \"times_seen\": 1.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.00676075821673893, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08702185545256513, \"functional effect\": -2.9546, \"times_seen\": 1.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05596388897948518, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.09088879366407819, \"functional effect\": -0.4162, \"times_seen\": 9.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.3075765477223282, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.07064375295883868, \"functional effect\": -0.0334, \"times_seen\": 75.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.051640198876908516, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08435644732387373, \"functional effect\": -0.078, \"times_seen\": 24.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.8516939569556179, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.048448250812177136, \"functional effect\": -0.2965, \"times_seen\": 54.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02809831762069796, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08574426729114633, \"functional effect\": -0.1427, \"times_seen\": 30.0}, {\"site\": 1147, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.04296402475567166, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08486528416774936, \"functional effect\": -0.6488, \"times_seen\": 29.0}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.20859744362847793, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.10103168996157288, \"functional effect\": 0.3094, \"times_seen\": 55.0}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01664049617561719, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.08642795586211899, \"functional effect\": -0.8579, \"times_seen\": 46.0}, {\"site\": 1148, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.015290558137555008, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.08836218502943459, \"functional effect\": -0.3312, \"times_seen\": 6.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.024461072247129505, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08892564961087925, \"functional effect\": -0.2535, \"times_seen\": 3.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.003400237377583709, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08722479481883218, \"functional effect\": -0.1685, \"times_seen\": 5.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.011692188394602497, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.0867249045526709, \"functional effect\": -0.0935, \"times_seen\": 3.0}, {\"site\": 1149, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01054838053558541, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08807221297249347, \"functional effect\": -2.4196, \"times_seen\": 2.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.18598151087737858, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.0768559537859298, \"functional effect\": -0.2024, \"times_seen\": 36.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.009576164854246715, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08801288210929717, \"functional effect\": 0.1902, \"times_seen\": 26.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07867893134906435, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08279017709761546, \"functional effect\": -0.1208, \"times_seen\": 48.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.02803810983412021, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08574784571910433, \"functional effect\": 0.2916, \"times_seen\": 58.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.008520343532900551, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08691578380562918, \"functional effect\": 0.0225, \"times_seen\": 43.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.008850593906378384, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08796862914327992, \"functional effect\": 0.1762, \"times_seen\": 1.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.00352425909125989, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08764445355958994, \"functional effect\": 0.4035, \"times_seen\": 12.0}, {\"site\": 1150, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.399921275986901, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.06626363101052109, \"functional effect\": 0.3282, \"times_seen\": 52.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.05222925757343351, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.09065381872345175, \"functional effect\": 0.3145, \"times_seen\": 32.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.00016003034989686352, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08742091666294577, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.03351739796275237, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08948562426109477, \"functional effect\": 0.3651, \"times_seen\": 36.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0808949049176259, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08266310934347831, \"functional effect\": 0.2984, \"times_seen\": 29.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03366118938743836, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.0854142835235114, \"functional effect\": 0.3142, \"times_seen\": 15.0}, {\"site\": 1151, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.005726956176165113, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.087778370727692, \"functional effect\": 0.4344, \"times_seen\": 16.0}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.01238499245247781, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.08818440402823333, \"functional effect\": -1.3143, \"times_seen\": 3.0}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.055006928423722595, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.0908285257988259, \"functional effect\": -0.2061, \"times_seen\": 38.0}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.923515249903756, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.16583237539077936, \"functional effect\": 0.3612, \"times_seen\": 83.0}, {\"site\": 1152, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.003388269573593836, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08722551839072204, \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.0055113083431467804, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08709725360638138, \"functional effect\": -0.2959, \"times_seen\": 1.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.02265133225106255, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08606861204239509, \"functional effect\": -0.3184, \"times_seen\": 47.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.05009434185246236, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.09051976743202787, \"functional effect\": -0.0529, \"times_seen\": 2.0}, {\"site\": 1153, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0020767076396290005, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08730485164113234, \"functional effect\": 0.4067, \"times_seen\": 1.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0007095964571997272, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.08738762173779259, \"functional effect\": -0.3787, \"times_seen\": 43.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.13398581172693283, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.07967641438434886, \"functional effect\": -0.3254, \"times_seen\": 78.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.2879102155536484, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.07161333828656792, \"functional effect\": -0.3259, \"times_seen\": 79.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.07853217937025186, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.0923217592348189, \"functional effect\": -0.3548, \"times_seen\": 54.0}, {\"site\": 1154, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.046721087142346567, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.08464456575417624, \"functional effect\": -0.2959, \"times_seen\": 31.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.09764796705035635, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.08170874929551636, \"functional effect\": -0.6253, \"times_seen\": 28.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.34374346207961093, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.06889479894254566, \"functional effect\": -0.0871, \"times_seen\": 31.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.016481544111911415, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.08643747877471394, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.2815223348105288, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.10626988171676359, \"functional effect\": -0.656, \"times_seen\": 25.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.8282215186048364, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.1552326423727905, \"functional effect\": -0.6445, \"times_seen\": 85.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.011232112808382669, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.086752565543321, \"functional effect\": -0.5265, \"times_seen\": 27.0}, {\"site\": 1155, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.003986660412775914, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.087189347109447, \"functional effect\": -0.2548, \"times_seen\": 19.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.5599797733218427, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.12889445623390816, \"functional effect\": -0.3597, \"times_seen\": 28.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.15449164311529445, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.07855193927842484, \"functional effect\": 0.152, \"times_seen\": 18.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.027679032119456787, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.08912422141102891, \"functional effect\": 0.2068, \"times_seen\": 24.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"R\", \"log2 fold change IC90\": -2.8098587384823928, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.012468429847258454, \"functional effect\": 0.0721, \"times_seen\": 43.0}, {\"site\": 1156, \"wildtype\": \"H\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.21931140926804318, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.07510074018414653, \"functional effect\": 0.0425, \"times_seen\": 61.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.05018162557739675, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.09052524408597531, \"functional effect\": -0.78, \"times_seen\": 36.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.00860172592486054, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.08795345567528987, \"functional effect\": -0.7148, \"times_seen\": 5.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.010494805276005964, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.0867969128694232, \"functional effect\": -0.2803, \"times_seen\": 8.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0023329979775678533, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.08728934358020833, \"functional effect\": -0.1738, \"times_seen\": 2.0}, {\"site\": 1157, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.5733332195937089, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.05875881562848433, \"functional effect\": 0.2119, \"times_seen\": 15.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.003038101590544229, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08724669215927153, \"functional effect\": -0.1953, \"times_seen\": 1.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.002961777570831241, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08761028918315637, \"functional effect\": 0.0086, \"times_seen\": 5.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.01396250145714439, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08658853627099544, \"functional effect\": -0.9118, \"times_seen\": 4.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.009808670598139153, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08802706747009177, \"functional effect\": -0.2703, \"times_seen\": 9.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.00485997999588722, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08713658396807257, \"functional effect\": 0.0661, \"times_seen\": 17.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.012212006714195341, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08669366227884782, \"functional effect\": -0.572, \"times_seen\": 8.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.02648322890738182, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.0890503798359751, \"functional effect\": -0.1152, \"times_seen\": 6.0}, {\"site\": 1158, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.012034429728274133, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.08816297856519652, \"functional effect\": -0.0636, \"times_seen\": 33.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.01598573120800693, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.08840477324914857, \"functional effect\": 0.0107, \"times_seen\": 6.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.7643476935872002, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.051472107083839765, \"functional effect\": -0.1481, \"times_seen\": 35.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.5432573039714786, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.1274090489228198, \"functional effect\": 0.0636, \"times_seen\": 43.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.4188416279175361, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.06540028434318082, \"functional effect\": 0.2868, \"times_seen\": 14.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.1055407802979565, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.0940663885352692, \"functional effect\": -0.0167, \"times_seen\": 26.0}, {\"site\": 1159, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.1950556804746516, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.07637406725584307, \"functional effect\": -0.0225, \"times_seen\": 52.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.08335748634990019, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.09263105997828712, \"functional effect\": -2.8361, \"times_seen\": 14.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.00879455804762424, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08689926520404621, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -1.3309040572046449, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.0347553356758826, \"functional effect\": -0.1275, \"times_seen\": 192.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.02560428992040433, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08899614383256743, \"functional effect\": -1.0516, \"times_seen\": 42.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.3437767235729307, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.06889321058366582, \"functional effect\": -0.0843, \"times_seen\": 153.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"F\", \"log2 fold change IC90\": -1.6439055246467447, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.027976839863989817, \"functional effect\": -0.7344, \"times_seen\": 46.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.1053034259266524, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08127632160130002, \"functional effect\": -0.0435, \"times_seen\": 209.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.016303253838106872, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08842423238955259, \"functional effect\": -0.3688, \"times_seen\": 136.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.3629253942869173, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.06798484317848148, \"functional effect\": -0.2986, \"times_seen\": 68.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.13243418761251885, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.07976215277490058, \"functional effect\": -0.2916, \"times_seen\": 72.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.14574351702337743, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.07902970478986694, \"functional effect\": -0.4725, \"times_seen\": 103.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.013293137527598744, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08662871987802082, \"functional effect\": -0.3362, \"times_seen\": 38.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.026073950264478885, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08586466677173858, \"functional effect\": -0.074, \"times_seen\": 180.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.4522619764477697, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.11962114380398567, \"functional effect\": -0.0814, \"times_seen\": 112.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06733779221103654, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08344356197878462, \"functional effect\": -0.204, \"times_seen\": 38.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.04795199772654037, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08457237762429065, \"functional effect\": -0.2112, \"times_seen\": 122.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.02846323748902419, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08917267981003538, \"functional effect\": -0.0991, \"times_seen\": 157.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.20079893354395548, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.10048703501449283, \"functional effect\": -0.1426, \"times_seen\": 99.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.42781904817208455, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.11761152904206165, \"functional effect\": -0.2857, \"times_seen\": 123.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.14584995090446895, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.09673168212618041, \"functional effect\": -0.7356, \"times_seen\": 53.0}, {\"site\": 1160, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.3060859822714563, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.10809474762169831, \"functional effect\": -0.5144, \"times_seen\": 141.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008454601403592497, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08691974455875379, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.010593766604432528, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08679095925970978, \"functional effect\": -0.0882, \"times_seen\": 10.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.017641079218637355, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08636803442136096, \"functional effect\": 0.2839, \"times_seen\": 2.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.038456496199822256, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08513085027330923, \"functional effect\": -0.1568, \"times_seen\": 12.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.06443280603918235, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.09142389865602193, \"functional effect\": -0.149, \"times_seen\": 18.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.002155146442796753, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08730010503722872, \"functional effect\": -0.0091, \"times_seen\": 9.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.2344053911793728, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.07431910587567754, \"functional effect\": 0.0547, \"times_seen\": 14.0}, {\"site\": 1161, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.010915228582438171, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08677162261230191, \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.7740970883198351, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.05112544331136835, \"functional effect\": 0.0419, \"times_seen\": 33.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0011431957950506517, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08749992206199414, \"functional effect\": -0.0693, \"times_seen\": 73.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07696689752095282, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08288848180766019, \"functional effect\": 0.0946, \"times_seen\": 173.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.1052756534693857, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08127788621809778, \"functional effect\": -0.0328, \"times_seen\": 21.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07531944061627391, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08298318872473873, \"functional effect\": -0.0022, \"times_seen\": 56.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.08163464739758101, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08262073466465882, \"functional effect\": -0.4093, \"times_seen\": 31.0}, {\"site\": 1162, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0013044851219135253, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08750970485880538, \"functional effect\": -0.294, \"times_seen\": 17.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.020114854177796123, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08622006689995487, \"functional effect\": -0.35, \"times_seen\": 1.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.010266035782503537, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08681067742786822, \"functional effect\": 0.0174, \"times_seen\": 7.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0016810793970808938, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.087532550959059, \"functional effect\": 0.0125, \"times_seen\": 8.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -1.5915686580522277, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.029010393771971437, \"functional effect\": -0.0089, \"times_seen\": 41.0}, {\"site\": 1163, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.02173322548511817, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08612340208581963, \"functional effect\": -0.9381, \"times_seen\": 2.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0038140873080518027, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08719977719748463, \"functional effect\": -2.5362, \"times_seen\": 3.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008265368736130705, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08693114622952443, \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.40880772721838066, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.06585672678929945, \"functional effect\": -0.085, \"times_seen\": 62.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.009750230061481624, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08684172033601686, \"functional effect\": -1.4702, \"times_seen\": 22.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.9053936602526056, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.04667806885948147, \"functional effect\": 0.0149, \"times_seen\": 94.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.052765145531764306, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.09068749826911199, \"functional effect\": 0.1787, \"times_seen\": 50.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0012424235303811926, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.0873553530378555, \"functional effect\": -0.1835, \"times_seen\": 36.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.02947405153428311, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08923517990808078, \"functional effect\": 0.0658, \"times_seen\": 25.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.018039789829727437, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08853073051152695, \"functional effect\": -0.0695, \"times_seen\": 17.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.190877902360199, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.03829777648536097, \"functional effect\": 0.1964, \"times_seen\": 29.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.11596876404615389, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08067768974379524, \"functional effect\": -0.2658, \"times_seen\": 61.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.00114390284849199, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08736131868033035, \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.015497969652504641, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08649642864391474, \"functional effect\": 0.0698, \"times_seen\": 25.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.013705968148573376, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08826518534245917, \"functional effect\": 0.0568, \"times_seen\": 47.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013530645126898099, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08661445956299064, \"functional effect\": 0.1486, \"times_seen\": 23.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.3163821416766886, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.10886895259840197, \"functional effect\": 0.0881, \"times_seen\": 144.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.1613022612778474, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.0781819882766397, \"functional effect\": 0.0842, \"times_seen\": 74.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.18681822798511116, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.07681139270737103, \"functional effect\": 0.066, \"times_seen\": 42.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05473518587657221, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08417567297222166, \"functional effect\": -0.1033, \"times_seen\": 91.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.16574807314766554, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.07794143334574391, \"functional effect\": -0.3422, \"times_seen\": 31.0}, {\"site\": 1164, \"wildtype\": \"G\", \"mutant\": \"Y\", \"log2 fold change IC90\": 1.1429888301224878, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.1930800721964018, \"functional effect\": -0.2037, \"times_seen\": 27.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.019987757779459665, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.08622766292154165, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.13668631998423125, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07952741161211414, \"functional effect\": 0.0497, \"times_seen\": 61.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.11581851820461476, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.08068609215611956, \"functional effect\": 0.1599, \"times_seen\": 32.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.21881425715043668, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07512662432789617, \"functional effect\": -0.0215, \"times_seen\": 81.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.17474089565491036, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07745710819817478, \"functional effect\": 0.0698, \"times_seen\": 112.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.32589590539808777, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.06975238904933159, \"functional effect\": 0.1006, \"times_seen\": 106.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -2.784093389313553, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.012693106064123756, \"functional effect\": 0.0377, \"times_seen\": 34.0}, {\"site\": 1165, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.24983649938168592, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07352842267675724, \"functional effect\": 0.0392, \"times_seen\": 92.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.007333217099678127, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.08698733218151895, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.37424474522819107, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.11332413792508139, \"functional effect\": -0.195, \"times_seen\": 80.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.028172704181384692, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.08573984635911894, \"functional effect\": -0.0663, \"times_seen\": 10.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0075898944143938905, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.08697185719331439, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.1865803458694874, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.07682405897611205, \"functional effect\": 0.3117, \"times_seen\": 42.0}, {\"site\": 1166, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.13002891460321322, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.07989524380484599, \"functional effect\": 0.2283, \"times_seen\": 35.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.030645468713675527, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.08930766513140187, \"functional effect\": -0.1606, \"times_seen\": 23.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.005546829578690332, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.08776741190978861, \"functional effect\": -0.7865, \"times_seen\": 2.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.5158373148970332, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.12501036828587261, \"functional effect\": -0.0314, \"times_seen\": 85.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.10803341487383156, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.08112266912975515, \"functional effect\": 0.1262, \"times_seen\": 29.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 2.0078040357635505, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.35161935273592543, \"functional effect\": -0.2179, \"times_seen\": 2.0}, {\"site\": 1167, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.2274955089338704, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.10236382414040371, \"functional effect\": -0.0629, \"times_seen\": 59.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0035181975494452482, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08721766328314966, \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 1.0231873259273492, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.17769434473267817, \"functional effect\": 0.0214, \"times_seen\": 21.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.01708760010485505, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08847231883270304, \"functional effect\": -0.7442, \"times_seen\": 3.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.02887399657161997, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08569817844718375, \"functional effect\": 0.0388, \"times_seen\": 148.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.002444323925300439, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08728260813459726, \"functional effect\": 0.1299, \"times_seen\": 1.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.09110729707382292, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08208002890721205, \"functional effect\": -0.3251, \"times_seen\": 11.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.13258847190959816, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.0797536233287362, \"functional effect\": 0.0186, \"times_seen\": 76.0}, {\"site\": 1168, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.1334243146056296, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.07970743049184702, \"functional effect\": 0.0614, \"times_seen\": 67.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008275190324640629, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.0869305544211266, \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.012209867563809313, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.0866937908236292, \"functional effect\": 0.2852, \"times_seen\": 21.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.025663541212220368, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08588909650107619, \"functional effect\": -0.0948, \"times_seen\": 8.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05557274975844103, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08412681854347283, \"functional effect\": 0.1903, \"times_seen\": 17.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.10090420963074744, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08152453609255012, \"functional effect\": -0.392, \"times_seen\": 24.0}, {\"site\": 1169, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.3603385765356395, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.06810685244230259, \"functional effect\": -0.0292, \"times_seen\": 27.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.001204765281449974, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08735763327898179, \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.05949639790087931, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.09111161197188855, \"functional effect\": 0.186, \"times_seen\": 22.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.01180746165509119, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08814910965536955, \"functional effect\": -0.059, \"times_seen\": 5.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.01723342142325986, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.0884812616805169, \"functional effect\": -0.6553, \"times_seen\": 21.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 1.7466601181455226, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.2934003433606834, \"functional effect\": -0.4981, \"times_seen\": 21.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.05907016326764757, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08392312343369697, \"functional effect\": -0.3446, \"times_seen\": 35.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.018347807386213326, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08854963397324864, \"functional effect\": -0.1164, \"times_seen\": 45.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.06502064971434064, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08357769010249919, \"functional effect\": -0.0951, \"times_seen\": 20.0}, {\"site\": 1170, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0009186762088893413, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08737495817560052, \"functional effect\": -0.4194, \"times_seen\": 1.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.018836286844573735, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.08629651203963551, \"functional effect\": 0.0621, \"times_seen\": 4.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.008871293832195318, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.08796989133460205, \"functional effect\": 0.0907, \"times_seen\": 10.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.7281023542737467, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.052781640142969106, \"functional effect\": 0.2213, \"times_seen\": 59.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.23030498711501582, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.07453063487306885, \"functional effect\": 0.2596, \"times_seen\": 37.0}, {\"site\": 1171, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.5554043447559475, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.1284863220320289, \"functional effect\": 0.0478, \"times_seen\": 62.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0380698296151575, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.08976844259328465, \"functional effect\": -0.4219, \"times_seen\": 19.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.001370602365689376, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.0875137154313158, \"functional effect\": -1.5856, \"times_seen\": 1.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03684596326803314, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.08522593800197056, \"functional effect\": -1.0889, \"times_seen\": 27.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.025961409727287704, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.0858713650914539, \"functional effect\": -0.2426, \"times_seen\": 12.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 1.2986090604581468, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.21507196834560785, \"functional effect\": -0.1875, \"times_seen\": 22.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.044983135161034575, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.09019963973668586, \"functional effect\": -0.3201, \"times_seen\": 15.0}, {\"site\": 1172, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04477403739598591, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.09018656755176299, \"functional effect\": -0.4335, \"times_seen\": 5.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.014851587489622741, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08653519101140021, \"functional effect\": -2.882, \"times_seen\": 6.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05653757721932829, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08407057607554635, \"functional effect\": -0.2905, \"times_seen\": 66.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.6368774906899418, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.05622692094991617, \"functional effect\": -0.7802, \"times_seen\": 38.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0782047517500806, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08281739273505767, \"functional effect\": -0.9151, \"times_seen\": 28.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.028051816519196728, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08574703105411917, \"functional effect\": -1.1258, \"times_seen\": 30.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.3106580729592565, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.10843785751356745, \"functional effect\": -0.4019, \"times_seen\": 42.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.07383839520731447, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08306842155166395, \"functional effect\": -0.6579, \"times_seen\": 15.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.0589548614765935, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08392983093102424, \"functional effect\": -0.2005, \"times_seen\": 22.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.054872397843874494, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.09082005647981106, \"functional effect\": -0.2854, \"times_seen\": 26.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.05335821840754453, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08425605204816145, \"functional effect\": -0.2019, \"times_seen\": 21.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.23894842836056607, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.07408544359436936, \"functional effect\": -0.3821, \"times_seen\": 81.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.23926382020155412, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.10320223833280777, \"functional effect\": -0.03, \"times_seen\": 44.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.007264552415430417, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08699147241883275, \"functional effect\": -0.3721, \"times_seen\": 13.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.3162900845154643, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.0702183673084603, \"functional effect\": -0.5789, \"times_seen\": 39.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08251867962955467, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08257012312375654, \"functional effect\": -0.3196, \"times_seen\": 28.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": -1.6615794031267064, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.027636197612494813, \"functional effect\": -0.2285, \"times_seen\": 104.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.08438074766421862, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.09269678377980403, \"functional effect\": -0.7665, \"times_seen\": 73.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.026156217515296117, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08585977062357199, \"functional effect\": -0.7113, \"times_seen\": 30.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.008817762723005405, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08689786750531837, \"functional effect\": 0.0842, \"times_seen\": 25.0}, {\"site\": 1173, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06145762250668927, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08378435721096868, \"functional effect\": -0.3186, \"times_seen\": 24.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05955688596294219, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.08389481502608614, \"functional effect\": 0.1103, \"times_seen\": 22.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0014800781297393706, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.08734096420930401, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.06766846077173003, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.08342443874074114, \"functional effect\": -0.1009, \"times_seen\": 20.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.1853291893756563, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.03844535621632176, \"functional effect\": 0.1073, \"times_seen\": 41.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.8102620478715219, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.1533121982320994, \"functional effect\": 0.0916, \"times_seen\": 26.0}, {\"site\": 1174, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.0037595177932393266, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08720307556574207, \"functional effect\": -0.1074, \"times_seen\": 34.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.013390272648641647, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08662288745489402, \"functional effect\": 0.0489, \"times_seen\": 29.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.002350914666934477, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08757320127092898, \"functional effect\": 0.1337, \"times_seen\": 2.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.039041709246493604, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08982893598327073, \"functional effect\": 0.008, \"times_seen\": 31.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03548677757287681, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.0853062685333625, \"functional effect\": -0.031, \"times_seen\": 8.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04567282809546796, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08470609065889909, \"functional effect\": 0.0274, \"times_seen\": 22.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.029480972205269983, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.0856621307975405, \"functional effect\": 0.191, \"times_seen\": 23.0}, {\"site\": 1175, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.011022821026706894, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08676515165164296, \"functional effect\": 0.1389, \"times_seen\": 35.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.00017657444701994816, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.0874199141698324, \"functional effect\": 0.3638, \"times_seen\": 21.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.011333608606948533, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08812016184295073, \"functional effect\": -0.878, \"times_seen\": 8.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.021578699907543658, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08874816168228893, \"functional effect\": -0.3533, \"times_seen\": 3.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.004844588792643646, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.0871375135782741, \"functional effect\": -0.3435, \"times_seen\": 1.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0012754200814738407, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08750794187534884, \"functional effect\": -0.0605, \"times_seen\": 5.0}, {\"site\": 1176, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.014726099407245747, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08654271831769651, \"functional effect\": 0.2336, \"times_seen\": 34.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.033092561048997646, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08544795561190514, \"functional effect\": 0.2389, \"times_seen\": 16.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.011908947217513753, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08671187548167754, \"functional effect\": -0.0602, \"times_seen\": 13.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.6355229855127116, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.1358235294106555, \"functional effect\": 0.0837, \"times_seen\": 86.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.03430441685843653, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.085376209941691, \"functional effect\": 0.0438, \"times_seen\": 19.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01151519660073979, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08813125397956059, \"functional effect\": -1.8418, \"times_seen\": 6.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.01899035051330942, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.0862872970309154, \"functional effect\": 0.1147, \"times_seen\": 35.0}, {\"site\": 1177, \"wildtype\": \"Q\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.022395945956467586, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08879844925460861, \"functional effect\": 0.0368, \"times_seen\": 11.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.052179115330739434, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08432494199096438, \"functional effect\": -0.328, \"times_seen\": 35.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07565723833073192, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.0829637610222441, \"functional effect\": -0.022, \"times_seen\": 16.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.5381201790751053, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.06021063601942699, \"functional effect\": -0.1419, \"times_seen\": 65.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.005268740366864159, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08775049577884061, \"functional effect\": 0.0397, \"times_seen\": 32.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.6187369893649911, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.13425235825600523, \"functional effect\": -0.0624, \"times_seen\": 63.0}, {\"site\": 1178, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.01954174837912461, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08862294593034922, \"functional effect\": -0.0284, \"times_seen\": 23.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.003976082995934452, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08718998635850737, \"functional effect\": 0.2404, \"times_seen\": 21.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.06909240453346936, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08334213922408946, \"functional effect\": -0.1308, \"times_seen\": 14.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.011060808450218554, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08676286707931427, \"functional effect\": -2.2387, \"times_seen\": 2.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.12759482523045557, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08003015541516599, \"functional effect\": 0.0599, \"times_seen\": 64.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.041505792468170245, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.0849511067831082, \"functional effect\": 0.1102, \"times_seen\": 43.0}, {\"site\": 1179, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0031039261137618406, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.0876189218381179, \"functional effect\": -2.2533, \"times_seen\": 1.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.004525920721186385, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08715676297581673, \"functional effect\": -1.1997, \"times_seen\": 1.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.01582341683698508, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08839482758663397, \"functional effect\": 0.0006, \"times_seen\": 9.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.07097666135077157, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08323335983337218, \"functional effect\": 0.1599, \"times_seen\": 19.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.006432619368244088, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08704165069570641, \"functional effect\": -3.0473, \"times_seen\": 1.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0063496298352604475, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08704665782022275, \"functional effect\": -1.5486, \"times_seen\": 2.0}, {\"site\": 1180, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.02976266104824261, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08564540674272599, \"functional effect\": 0.3074, \"times_seen\": 31.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.0098055867905595, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08683838825181207, \"functional effect\": 0.0134, \"times_seen\": 36.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.3718126206924506, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.06756733322738567, \"functional effect\": 0.2674, \"times_seen\": 96.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.004633379367724306, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08771185908427391, \"functional effect\": 0.0345, \"times_seen\": 13.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.02231888766970692, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08879370641330578, \"functional effect\": -0.0548, \"times_seen\": 17.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.10489907865574913, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08129910428491631, \"functional effect\": 0.0246, \"times_seen\": 105.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.029763169871707976, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.0856453765364913, \"functional effect\": 0.029, \"times_seen\": 13.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.007313549543412507, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08698851804538005, \"functional effect\": -1.9232, \"times_seen\": 1.0}, {\"site\": 1181, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.26462527276045256, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.07277854774767575, \"functional effect\": 0.073, \"times_seen\": 95.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.03827072089254126, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08514181324727353, \"functional effect\": 0.1659, \"times_seen\": 59.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.21911227626260243, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.07511110694069435, \"functional effect\": -0.3745, \"times_seen\": 14.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.014541513997040498, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08655379172176375, \"functional effect\": 0.091, \"times_seen\": 2.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.021916792322650838, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08611244454152357, \"functional effect\": 0.157, \"times_seen\": 9.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0527453532129159, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08429185210971461, \"functional effect\": 0.0256, \"times_seen\": 41.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.07794101568164549, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08283253379363185, \"functional effect\": 0.0854, \"times_seen\": 20.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07637886500412241, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08292227346550456, \"functional effect\": -0.0833, \"times_seen\": 84.0}, {\"site\": 1182, \"wildtype\": \"R\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.02107074609721177, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08616295866485203, \"functional effect\": -0.1672, \"times_seen\": 1.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.04119795597769809, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08496923524410256, \"functional effect\": 0.4069, \"times_seen\": 15.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.014241763921819547, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08657177695099615, \"functional effect\": -0.178, \"times_seen\": 15.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.015353187327640409, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08650510946840019, \"functional effect\": -0.0126, \"times_seen\": 4.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0007267826215420218, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08738658073533492, \"functional effect\": -2.4142, \"times_seen\": 1.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.013058488710190974, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08822558094337357, \"functional effect\": -2.1079, \"times_seen\": 1.0}, {\"site\": 1183, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004444312508764446, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08716169326849788, \"functional effect\": -2.0339, \"times_seen\": 1.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.6129936754131118, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.05716550527757014, \"functional effect\": 0.3598, \"times_seen\": 44.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.016058946686384874, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08840925982588373, \"functional effect\": 0.0092, \"times_seen\": 5.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.020539277863375265, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08868424410417314, \"functional effect\": -0.3623, \"times_seen\": 23.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.0024156490473484183, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08728434297317209, \"functional effect\": -0.2011, \"times_seen\": 36.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.08428045300703631, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.0926903398198981, \"functional effect\": -0.1086, \"times_seen\": 28.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.007934299968467146, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.0869510974244204, \"functional effect\": -0.02, \"times_seen\": 22.0}, {\"site\": 1184, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.055824924039677114, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08411211497451841, \"functional effect\": -0.1487, \"times_seen\": 36.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.8575448523165765, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.04825216528320842, \"functional effect\": -2.5368, \"times_seen\": 2.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.04980489094951246, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08446382869703989, \"functional effect\": -0.0764, \"times_seen\": 45.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.52929553787158, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.06058005963154048, \"functional effect\": 0.1741, \"times_seen\": 70.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.08747456874681316, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.09289578286108094, \"functional effect\": 0.0898, \"times_seen\": 45.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.05790499704509279, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08399092978463137, \"functional effect\": 0.0326, \"times_seen\": 130.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.14029927375292492, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.0793284995943805, \"functional effect\": -0.1775, \"times_seen\": 21.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.05347935738625645, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.0842489776053272, \"functional effect\": -0.3296, \"times_seen\": 17.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.00039615935360034853, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08745462578793177, \"functional effect\": 0.2637, \"times_seen\": 12.0}, {\"site\": 1185, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.003698363324273939, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.0872067720994212, \"functional effect\": 0.1173, \"times_seen\": 33.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05026688180725846, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.0844367853730214, \"functional effect\": 0.2116, \"times_seen\": 18.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.16325678264299995, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.07807614130365685, \"functional effect\": 0.1328, \"times_seen\": 35.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.017642704139615984, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08636793714428714, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": -2.056113727334958, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.021023819707062467, \"functional effect\": -0.1789, \"times_seen\": 38.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01766251762973231, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08636675100413302, \"functional effect\": -0.061, \"times_seen\": 1.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.031218869201437863, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08555900274578712, \"functional effect\": -0.0626, \"times_seen\": 16.0}, {\"site\": 1186, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.014206237231956454, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.08657390882672356, \"functional effect\": -0.0999, \"times_seen\": 3.0}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07393882874556178, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.08306263892618285, \"functional effect\": 0.2268, \"times_seen\": 49.0}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.05674027601202777, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.08405876498123063, \"functional effect\": -0.0464, \"times_seen\": 57.0}, {\"site\": 1187, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.05318332778691778, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.09071378892537876, \"functional effect\": -0.6084, \"times_seen\": 42.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.018472902407592827, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08855731237949481, \"functional effect\": -2.9248, \"times_seen\": 4.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.061634721056597626, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.0837740728632331, \"functional effect\": -0.0125, \"times_seen\": 72.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.018192154310026125, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08633505019244143, \"functional effect\": 0.0765, \"times_seen\": 35.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"D\", \"log2 fold change IC90\": -2.5045859677700792, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.015406643271552944, \"functional effect\": -0.254, \"times_seen\": 38.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.008316594472204536, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08793607444237343, \"functional effect\": -0.1586, \"times_seen\": 53.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"F\", \"log2 fold change IC90\": 1.801584912802366, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.3047857292130496, \"functional effect\": -0.0813, \"times_seen\": 44.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.15762431857059006, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.07838155624443693, \"functional effect\": -0.3656, \"times_seen\": 101.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.047914379994788106, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.0845745828460475, \"functional effect\": 0.0095, \"times_seen\": 23.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0004800172274461185, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08745970931002985, \"functional effect\": 0.0895, \"times_seen\": 30.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.41921455231398813, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.11691216012725282, \"functional effect\": -0.0082, \"times_seen\": 94.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.00746781221550302, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08697921714432275, \"functional effect\": 0.0308, \"times_seen\": 57.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0850801382339369, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08242365259343558, \"functional effect\": 0.0363, \"times_seen\": 102.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.07197565871560412, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.09190314259692646, \"functional effect\": -2.8372, \"times_seen\": 6.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.14427825441185432, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.09662635836911614, \"functional effect\": 0.0239, \"times_seen\": 43.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.038549345541677806, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08979828434854431, \"functional effect\": -0.077, \"times_seen\": 153.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.4190922303802662, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.06538892501326289, \"functional effect\": 0.0966, \"times_seen\": 80.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0942200295735748, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.0819031254447743, \"functional effect\": 0.1724, \"times_seen\": 74.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.6247145378738949, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.056702958024594, \"functional effect\": 0.0846, \"times_seen\": 94.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.09196463409840828, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08203126645862052, \"functional effect\": -0.0432, \"times_seen\": 39.0}, {\"site\": 1188, \"wildtype\": \"K\", \"mutant\": \"Y\", \"log2 fold change IC90\": 1.138736017417561, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.19251174398398951, \"functional effect\": -0.0513, \"times_seen\": 22.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.2504402094222595, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.07349766041627302, \"functional effect\": -0.0737, \"times_seen\": 84.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": 1.3016956762767606, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.21553260289986845, \"functional effect\": -0.1333, \"times_seen\": 26.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.07639236494966106, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.08292149752817446, \"functional effect\": -0.2161, \"times_seen\": 28.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.8644142825617542, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.04802295745628181, \"functional effect\": -0.2615, \"times_seen\": 42.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.5562433803956603, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.12856106822208532, \"functional effect\": -0.1757, \"times_seen\": 71.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.35050357935605436, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.0685727298670328, \"functional effect\": -0.0432, \"times_seen\": 71.0}, {\"site\": 1189, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.076549724122616, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.08291245351935098, \"functional effect\": -0.1824, \"times_seen\": 31.0}, {\"site\": 1190, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.01176758736468784, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": 0.08814667335765969, \"functional effect\": 0.1436, \"times_seen\": 11.0}, {\"site\": 1190, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.0014454573873479513, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": 0.08734306017915092, \"functional effect\": -3.0572, \"times_seen\": 7.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.004634221741201974, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08715022048985771, \"functional effect\": -1.2563, \"times_seen\": 2.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.02585332236186285, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08587779885399899, \"functional effect\": -1.0998, \"times_seen\": 11.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06421976247414941, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08362409969453054, \"functional effect\": -1.1808, \"times_seen\": 25.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.022439681643790056, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08608123966623726, \"functional effect\": -0.4681, \"times_seen\": 14.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.00399784894154852, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08718867093277179, \"functional effect\": -0.7439, \"times_seen\": 1.0}, {\"site\": 1191, \"wildtype\": \"N\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.016238536428265723, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.0884202658832756, \"functional effect\": -1.0239, \"times_seen\": 10.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.00817955890641432, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08693631694716786, \"functional effect\": -2.6467, \"times_seen\": 2.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.025929839262798512, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08587324423324617, \"functional effect\": -0.1746, \"times_seen\": 8.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.19143178477756595, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.07656615189430167, \"functional effect\": -0.0335, \"times_seen\": 49.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.4376797415799792, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.06455186575072319, \"functional effect\": 0.0492, \"times_seen\": 62.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.06827006797124378, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08338965780743049, \"functional effect\": -0.2683, \"times_seen\": 79.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.08095604374115725, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.09247699891042474, \"functional effect\": -0.1986, \"times_seen\": 25.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.040556381179784294, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08500702995577335, \"functional effect\": -0.1909, \"times_seen\": 9.0}, {\"site\": 1192, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.006478421222215718, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08782410427332699, \"functional effect\": 0.0115, \"times_seen\": 14.0}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -3.867719801000936, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.005989131586716448, \"functional effect\": -1.122, \"times_seen\": 36.0}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -2.8979044353479666, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.011730252762428348, \"functional effect\": -0.0384, \"times_seen\": 29.0}, {\"site\": 1193, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.3911963845509957, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.06666558339708407, \"functional effect\": -1.4316, \"times_seen\": 26.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.027358472696925054, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08910442066702938, \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.19482167909150644, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.0763864559355797, \"functional effect\": -0.2202, \"times_seen\": 30.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00887843604853436, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08689421304502802, \"functional effect\": -0.066, \"times_seen\": 12.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.13268191132283386, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.07974845807188415, \"functional effect\": 0.0823, \"times_seen\": 35.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.2422437701314807, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.10341562739221709, \"functional effect\": -2.5545, \"times_seen\": 25.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.009992686825971953, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08682712709713099, \"functional effect\": -1.8685, \"times_seen\": 2.0}, {\"site\": 1194, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.03248959272027211, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08942189558877252, \"functional effect\": -0.832, \"times_seen\": 8.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.02636820608061701, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08904328033274327, \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.0018298110124105945, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08754157540873687, \"functional effect\": -0.4286, \"times_seen\": 4.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.05137029686367565, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08437223035783895, \"functional effect\": -0.5658, \"times_seen\": 8.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.04407145386086198, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08480016560745939, \"functional effect\": -0.3756, \"times_seen\": 17.0}, {\"site\": 1195, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.021777030499649786, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.0861207871329026, \"functional effect\": 0.0335, \"times_seen\": 32.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.02602360250304296, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.0890220139058805, \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.03719948579608879, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08520505652874288, \"functional effect\": -0.3481, \"times_seen\": 24.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.09644305549491729, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.0934750664456663, \"functional effect\": -0.5742, \"times_seen\": 98.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.06030909510301509, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08385108437189305, \"functional effect\": -0.7052, \"times_seen\": 45.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.009702497740742921, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08684459358733068, \"functional effect\": -0.3864, \"times_seen\": 124.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.5801581141013965, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.05848150431156076, \"functional effect\": -0.4627, \"times_seen\": 21.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.09561339523201157, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.09342132656929021, \"functional effect\": -0.6228, \"times_seen\": 14.0}, {\"site\": 1196, \"wildtype\": \"D\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009948592959798625, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08682978088197217, \"functional effect\": -0.6752, \"times_seen\": 80.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.8834153072697551, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.047394617632825285, \"functional effect\": -0.6132, \"times_seen\": 115.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.0008199507903830762, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.08748031934377919, \"functional effect\": -1.243, \"times_seen\": 2.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0640481120714848, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.09139952376550477, \"functional effect\": -0.2187, \"times_seen\": 119.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.05640774794836373, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.0840781419937921, \"functional effect\": -1.2615, \"times_seen\": 17.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.007359078794263848, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.08698577286399821, \"functional effect\": -0.891, \"times_seen\": 2.0}, {\"site\": 1197, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.03525651147030546, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.0853198852084816, \"functional effect\": -0.4283, \"times_seen\": 17.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.057879773356122904, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.09100957323917643, \"functional effect\": 0.1791, \"times_seen\": 14.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.18709536169468327, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.0995370684632597, \"functional effect\": -0.1289, \"times_seen\": 77.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.10929103660872211, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.09431123028489379, \"functional effect\": -0.0713, \"times_seen\": 48.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.08361385012699143, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.08250746674371598, \"functional effect\": -0.2985, \"times_seen\": 86.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.04045154668713888, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.08501320727835257, \"functional effect\": -0.1313, \"times_seen\": 14.0}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.15551415516041478, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.07849628521088746, \"functional effect\": -0.0902, \"times_seen\": 72.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -7.644182472195256e-05, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08742598190333416, \"functional effect\": -3.0098, \"times_seen\": 1.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.040558227132051185, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08992341112060996, \"functional effect\": -0.2665, \"times_seen\": 11.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.18062853132671916, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.07714165001934047, \"functional effect\": -0.1355, \"times_seen\": 30.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.06725455382533013, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08344837651517314, \"functional effect\": -0.5713, \"times_seen\": 54.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.5831902864677978, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.1309849200556538, \"functional effect\": -0.5992, \"times_seen\": 119.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.49770738553697813, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.12344922904957346, \"functional effect\": -0.2673, \"times_seen\": 22.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.07960654076416952, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08273696261929006, \"functional effect\": -0.4779, \"times_seen\": 7.0}, {\"site\": 1199, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.05729404380995068, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.0909726311448668, \"functional effect\": -0.4334, \"times_seen\": 13.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.1735054157285003, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.07752346850800301, \"functional effect\": -0.5025, \"times_seen\": 48.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.026503790073993505, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08583908787025542, \"functional effect\": -2.377, \"times_seen\": 5.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.02032164794952384, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08867086713384582, \"functional effect\": -0.37, \"times_seen\": 12.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.08013180229265787, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.0827068449354372, \"functional effect\": -0.075, \"times_seen\": 28.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.008320242087219204, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.0879362967744269, \"functional effect\": -1.7428, \"times_seen\": 12.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.24416682110646776, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.10355356792803404, \"functional effect\": -1.8301, \"times_seen\": 8.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.004343284345168068, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08716779718782079, \"functional effect\": -1.7863, \"times_seen\": 2.0}, {\"site\": 1200, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.004574024657977328, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08715385694689019, \"functional effect\": -1.007, \"times_seen\": 1.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.016803587895398025, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08641818603075829, \"functional effect\": -0.4525, \"times_seen\": 2.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.019248330107816833, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08627186870329787, \"functional effect\": -1.2555, \"times_seen\": 4.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.10454963638006583, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.09400178630990902, \"functional effect\": -0.3785, \"times_seen\": 34.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01878631891111325, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08629950098249901, \"functional effect\": -0.9138, \"times_seen\": 2.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.03099839036530741, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08557207923826779, \"functional effect\": -0.8861, \"times_seen\": 8.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.08037684797488155, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08269279814552936, \"functional effect\": -0.3427, \"times_seen\": 31.0}, {\"site\": 1201, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -2.1229332273620636, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.020072291238277716, \"functional effect\": -1.2251, \"times_seen\": 12.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.13657545684269357, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.09611182838615405, \"functional effect\": 0.1113, \"times_seen\": 12.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.00918579297486931, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.08687570276201734, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.007164723739142825, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.0878658928986313, \"functional effect\": 0.1242, \"times_seen\": 56.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0016281344860978374, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.08752933869454692, \"functional effect\": -0.0272, \"times_seen\": 17.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.06954438680382437, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.09174839516002001, \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 1202, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.1995712347083838, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.1004015593347792, \"functional effect\": 0.1046, \"times_seen\": 22.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.00258208149036358, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.087274274241993, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.00824411696515449, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08793165685779344, \"functional effect\": -1.5381, \"times_seen\": 7.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.038944142017661755, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08510208002964108, \"functional effect\": -0.1585, \"times_seen\": 21.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.008276003698411085, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08693050541075997, \"functional effect\": -0.9419, \"times_seen\": 13.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.009770362200367356, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08684050850861955, \"functional effect\": -1.0559, \"times_seen\": 2.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0024032312127887532, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08728509426652563, \"functional effect\": -0.5054, \"times_seen\": 1.0}, {\"site\": 1203, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005507945064172477, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08709745665185871, \"functional effect\": -1.7288, \"times_seen\": 1.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.004460420882174275, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08716072007234478, \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.0076656864737601315, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.0869672882422678, \"functional effect\": -0.9284, \"times_seen\": 8.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.4836555586510541, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.06252715940669916, \"functional effect\": -0.2349, \"times_seen\": 79.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.002704735785526029, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08759468124211653, \"functional effect\": -1.075, \"times_seen\": 14.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.022097027100871997, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08610168725223848, \"functional effect\": -1.1686, \"times_seen\": 91.0}, {\"site\": 1204, \"wildtype\": \"E\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.018409784475494337, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08632202755520235, \"functional effect\": -0.544, \"times_seen\": 20.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0058808419402461695, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08707494727076338, \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.017894851837053794, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08635284346690364, \"functional effect\": 0.2082, \"times_seen\": 101.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.2757429797583414, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.07221985663426557, \"functional effect\": -0.5391, \"times_seen\": 131.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.05107846199197021, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08438929928016381, \"functional effect\": -1.0514, \"times_seen\": 61.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0724718428797847, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08314714305664812, \"functional effect\": -0.3741, \"times_seen\": 25.0}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1205, \"wildtype\": \"Q\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.2690621749100885, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.07255506652016874, \"functional effect\": -1.2458, \"times_seen\": 30.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.014794329920185395, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08653862548153543, \"functional effect\": -1.5884, \"times_seen\": 5.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.007712113212058466, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08696448963102166, \"functional effect\": -0.9888, \"times_seen\": 1.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.1212938221325616, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08038045333236978, \"functional effect\": -1.1283, \"times_seen\": 22.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.002190365971779207, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.0872979738653852, \"functional effect\": -0.3489, \"times_seen\": 1.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0061831050273647775, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08705670586514486, \"functional effect\": -1.2513, \"times_seen\": 1.0}, {\"site\": 1206, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.011386698076004917, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.08812340462021892, \"functional effect\": -0.2619, \"times_seen\": 14.0}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 1.2133411411611275, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.2027288740962661, \"functional effect\": -0.1508, \"times_seen\": 17.0}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.04446064218884317, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.0901669785412263, \"functional effect\": -0.6196, \"times_seen\": 43.0}, {\"site\": 1207, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.6528086896678704, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.05560944144557431, \"functional effect\": -0.0089, \"times_seen\": 38.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.027929242690475035, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.08575431657746323, \"functional effect\": -2.2165, \"times_seen\": 6.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0022584461652966083, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.08756758850941594, \"functional effect\": -0.5475, \"times_seen\": 2.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.09591756755815137, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.0934410252423975, \"functional effect\": -0.6971, \"times_seen\": 21.0}, {\"site\": 1208, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.010968700442252443, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.08809787598259772, \"functional effect\": -0.1191, \"times_seen\": 5.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.04343647667084211, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.09010299194852292, \"functional effect\": -2.4534, \"times_seen\": 5.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.04766206524615442, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08458937549463508, \"functional effect\": -2.3843, \"times_seen\": 14.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.0027770924328467212, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08726247806346997, \"functional effect\": -2.2355, \"times_seen\": 1.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.02223059208169491, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08878827224157287, \"functional effect\": -2.2128, \"times_seen\": 14.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006667802133826114, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08702746264687163, \"functional effect\": -2.4587, \"times_seen\": 2.0}, {\"site\": 1209, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.009527524474474969, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.08685512693171407, \"functional effect\": -2.2115, \"times_seen\": 3.0}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05119444304855198, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.0843825153331706, \"functional effect\": -1.333, \"times_seen\": 6.0}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.09886722263925894, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.0816397244766577, \"functional effect\": -1.0767, \"times_seen\": 37.0}, {\"site\": 1210, \"wildtype\": \"P\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0072976177293020954, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.08698947867289468, \"functional effect\": -1.9568, \"times_seen\": 4.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.02097399437195839, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08616873722110058, \"functional effect\": -2.4638, \"times_seen\": 8.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.035866728026960046, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.0852838050973187, \"functional effect\": -2.5278, \"times_seen\": 19.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.02739973562833334, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08910696920436662, \"functional effect\": -0.6012, \"times_seen\": 19.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.049716274173976456, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.09049604924237309, \"functional effect\": -1.6721, \"times_seen\": 11.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0813169471941631, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.09250013577732859, \"functional effect\": -1.6378, \"times_seen\": 23.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.021759276639385164, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08612184694511874, \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.006269167594198259, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08705151273708571, \"functional effect\": -1.5455, \"times_seen\": 1.0}, {\"site\": 1211, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.03404060333838281, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.08539182339934698, \"functional effect\": -2.2095, \"times_seen\": 6.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.08565455302908617, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.09277866511987075, \"functional effect\": -0.3552, \"times_seen\": 50.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.25896053316534506, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.10462089191005133, \"functional effect\": -1.0761, \"times_seen\": 111.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.3629395320761293, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.06798417695960238, \"functional effect\": -0.9324, \"times_seen\": 37.0}, {\"site\": 1212, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.6519328279154569, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.1373772651347724, \"functional effect\": -1.6606, \"times_seen\": 39.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.012800106747516665, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.08820978144527965, \"functional effect\": -0.6364, \"times_seen\": 35.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.11210006495641543, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.08089432358136822, \"functional effect\": -0.7324, \"times_seen\": 45.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.0027136285306204374, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.08726631680903219, \"functional effect\": -0.375, \"times_seen\": 1.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.7671613481390805, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.14879971769677636, \"functional effect\": -0.4035, \"times_seen\": 72.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.772437143153081, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.05118430140081135, \"functional effect\": -0.1313, \"times_seen\": 114.0}, {\"site\": 1213, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.05111567262021289, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.09058387200927591, \"functional effect\": -0.0003, \"times_seen\": 69.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.006583597564632655, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.087830507119744, \"functional effect\": -2.8152, \"times_seen\": 8.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.01787420386911909, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08635407936461716, \"functional effect\": -1.7056, \"times_seen\": 3.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.005532303848374814, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08709598609142809, \"functional effect\": -1.4455, \"times_seen\": 59.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.026041162126946557, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08902309743535292, \"functional effect\": -2.4405, \"times_seen\": 1.0}, {\"site\": 1214, \"wildtype\": \"W\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.11935691424658784, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08048844156810467, \"functional effect\": -0.4166, \"times_seen\": 12.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03921043907661531, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08983944250546944, \"functional effect\": -0.5232, \"times_seen\": 6.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.01872475998586379, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08857277356606146, \"functional effect\": -1.3295, \"times_seen\": 12.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005209420785059987, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08711548083226932, \"functional effect\": -1.5515, \"times_seen\": 1.0}, {\"site\": 1215, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.005312989116067875, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08710922720218385, \"functional effect\": -0.9749, \"times_seen\": 1.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.011807846951430789, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08814913319709727, \"functional effect\": -2.5133, \"times_seen\": 9.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.6583248643146619, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.13798728224881587, \"functional effect\": 0.3553, \"times_seen\": 153.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.558546842337818, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.12876649768292403, \"functional effect\": 0.3015, \"times_seen\": 136.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.06716105697676263, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.09159695208889677, \"functional effect\": -0.747, \"times_seen\": 89.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.34649445306353577, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.06876355264357194, \"functional effect\": -0.219, \"times_seen\": 52.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.009810347576304227, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.0880271697921707, \"functional effect\": 0.0226, \"times_seen\": 32.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"H\", \"log2 fold change IC90\": -0.12770357041932964, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08002412325581747, \"functional effect\": -0.5841, \"times_seen\": 20.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.047252806369394676, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.09034165495208003, \"functional effect\": -0.1738, \"times_seen\": 43.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.18999706296005983, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.09973746943763948, \"functional effect\": -1.1434, \"times_seen\": 27.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -5.8709678234156355, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.001493915769207748, \"functional effect\": -0.0576, \"times_seen\": 87.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.03796396081794166, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08976185538803202, \"functional effect\": 0.1474, \"times_seen\": 22.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.023268742946575462, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08603178630237143, \"functional effect\": -0.1172, \"times_seen\": 28.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.10316315251963419, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08139698649638548, \"functional effect\": -0.8864, \"times_seen\": 48.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.15961837942611834, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.07827329384462041, \"functional effect\": -0.063, \"times_seen\": 24.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.025314216340943226, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08590989565087047, \"functional effect\": -1.5016, \"times_seen\": 105.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.9495964406778649, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.04526958545216969, \"functional effect\": 0.0718, \"times_seen\": 263.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.21673060846912506, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.10160286259573621, \"functional effect\": -0.0003, \"times_seen\": 56.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.022532014354526928, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08607573062957889, \"functional effect\": -0.0735, \"times_seen\": 166.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.04643001649710629, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08466164492420923, \"functional effect\": -0.1293, \"times_seen\": 51.0}, {\"site\": 1216, \"wildtype\": \"G\", \"mutant\": \"Y\", \"log2 fold change IC90\": 1.0714448363711226, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.1837386683149585, \"functional effect\": -0.5349, \"times_seen\": 27.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.11682729744654642, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.09480517643722583, \"functional effect\": -1.1032, \"times_seen\": 79.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.018426431638535492, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08632103149675949, \"functional effect\": -1.0528, \"times_seen\": 26.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.06674485367546204, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08347786380334246, \"functional effect\": -2.1484, \"times_seen\": 11.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.014746630237759809, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08832887681310393, \"functional effect\": -1.2837, \"times_seen\": 4.0}, {\"site\": 1217, \"wildtype\": \"F\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007403835356904223, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08698307435621008, \"functional effect\": -0.9808, \"times_seen\": 2.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0563892466471917, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.09091559485487989, \"functional effect\": 0.065, \"times_seen\": 36.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.012715378552998195, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.08666341920268954, \"functional effect\": -0.1515, \"times_seen\": 48.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.025154984654939098, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.08591937813475185, \"functional effect\": -0.4276, \"times_seen\": 6.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.9012873143275106, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.16329693987241783, \"functional effect\": -0.0778, \"times_seen\": 52.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.9544880083952217, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.04511635538129756, \"functional effect\": -0.1469, \"times_seen\": 133.0}, {\"site\": 1218, \"wildtype\": \"I\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.025388253332349855, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.08590548699427808, \"functional effect\": -1.1376, \"times_seen\": 23.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.010147698568541131, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.08804775593440721, \"functional effect\": 0.2087, \"times_seen\": 5.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.00915877344526371, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.08798742246172374, \"functional effect\": 0.1067, \"times_seen\": 1.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.023387074106026993, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.0888594745431666, \"functional effect\": 0.0033, \"times_seen\": 39.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.35710904521179887, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.1119860855640566, \"functional effect\": -0.0723, \"times_seen\": 95.0}, {\"site\": 1219, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.641686641154823, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.13640505240563455, \"functional effect\": -0.6226, \"times_seen\": 79.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.020508047193363587, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08868232433713544, \"functional effect\": -0.387, \"times_seen\": 1.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.0017780983884695977, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08732292388357339, \"functional effect\": -0.4959, \"times_seen\": 29.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.016203306729200753, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08645415066757976, \"functional effect\": -1.5139, \"times_seen\": 11.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.1291884637598763, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.07994180082880196, \"functional effect\": -2.5374, \"times_seen\": 22.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0005366056762246652, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08746313990776927, \"functional effect\": -0.6865, \"times_seen\": 41.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.05234301323496679, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08431536276884699, \"functional effect\": -0.8444, \"times_seen\": 19.0}, {\"site\": 1220, \"wildtype\": \"G\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.048325199568105534, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.09040883324679562, \"functional effect\": -1.0369, \"times_seen\": 19.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.09628188101383109, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08178615584504251, \"functional effect\": -0.2175, \"times_seen\": 34.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.013367350045935558, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08662426379414292, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.070060282095829, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.0832862452672997, \"functional effect\": -0.0817, \"times_seen\": 24.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.010475830153712343, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08806778410024886, \"functional effect\": -1.9729, \"times_seen\": 1.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.04176608231789774, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08493578135700933, \"functional effect\": -0.298, \"times_seen\": 44.0}, {\"site\": 1221, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.033736110761223105, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08540984794348946, \"functional effect\": -0.2853, \"times_seen\": 16.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.020434715010548735, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08867781672952699, \"functional effect\": 0.1961, \"times_seen\": 50.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.1002209132160256, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.09372016208795927, \"functional effect\": 0.0194, \"times_seen\": 17.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.5218492326786502, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.12553239139179798, \"functional effect\": 0.2032, \"times_seen\": 21.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.018382166959150143, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08855174291779469, \"functional effect\": 0.173, \"times_seen\": 3.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01784603525471866, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08635576544410158, \"functional effect\": 0.2097, \"times_seen\": 19.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.07684234345313391, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.0922136856024235, \"functional effect\": 0.1205, \"times_seen\": 16.0}, {\"site\": 1222, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.008725196861287627, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08690344320483631, \"functional effect\": 0.1733, \"times_seen\": 40.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.0008867743624215789, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.08748437140096477, \"functional effect\": -1.1596, \"times_seen\": 5.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0016437926959189675, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.08733105346837934, \"functional effect\": -0.3103, \"times_seen\": 21.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.7463513485034502, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.052118197436058805, \"functional effect\": -0.0057, \"times_seen\": 66.0}, {\"site\": 1223, \"wildtype\": \"A\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.22609458414607753, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.10226447229468816, \"functional effect\": -0.1725, \"times_seen\": 94.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.0028310211140740644, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08725921620820958, \"functional effect\": -2.3523, \"times_seen\": 1.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.025368856439996812, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08590664199283163, \"functional effect\": -2.8078, \"times_seen\": 7.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0015559670564343593, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.0875249603545467, \"functional effect\": -0.6899, \"times_seen\": 13.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.6745123545847812, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.13954426134081488, \"functional effect\": -0.1915, \"times_seen\": 77.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.024115729997424958, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08598129300945784, \"functional effect\": -1.8437, \"times_seen\": 3.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.045295841628380074, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08472822785455238, \"functional effect\": -0.466, \"times_seen\": 13.0}, {\"site\": 1224, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.10125646459476942, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.09378745758709087, \"functional effect\": -0.2212, \"times_seen\": 41.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.027720110121661964, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08912675909015101, \"functional effect\": -2.4181, \"times_seen\": 10.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.035249096366531375, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08959310030261963, \"functional effect\": -1.0511, \"times_seen\": 1.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.014698814248595616, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.0865443550836533, \"functional effect\": 0.0799, \"times_seen\": 139.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.3163776700359398, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.0702141045048937, \"functional effect\": -0.0272, \"times_seen\": 55.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"D\", \"log2 fold change IC90\": 1.6053159578722853, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.26601846663397505, \"functional effect\": -1.5675, \"times_seen\": 37.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"E\", \"log2 fold change IC90\": -2.077860908169721, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.020709283326280026, \"functional effect\": -1.0143, \"times_seen\": 89.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.3200243948997456, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.10914415230788709, \"functional effect\": 0.1416, \"times_seen\": 65.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.021336054648523874, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08873323648378642, \"functional effect\": 0.1317, \"times_seen\": 139.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.015093349895820452, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08835010724466015, \"functional effect\": -0.8873, \"times_seen\": 39.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.2529963422747274, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.10418927542530801, \"functional effect\": 0.0404, \"times_seen\": 95.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.07109695001790585, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08322642031236945, \"functional effect\": -0.7357, \"times_seen\": 42.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0766389990407481, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.09220068922011161, \"functional effect\": 0.0479, \"times_seen\": 209.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.2562095024788545, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.07320433243051506, \"functional effect\": 0.0496, \"times_seen\": 59.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.05968719239707729, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08388723785960643, \"functional effect\": -0.8236, \"times_seen\": 33.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"P\", \"log2 fold change IC90\": -1.7842379642451969, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.025383668260079765, \"functional effect\": -0.7, \"times_seen\": 66.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.7639237452312337, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.05148723482815986, \"functional effect\": -0.7127, \"times_seen\": 46.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.020615686188753167, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08619014077291352, \"functional effect\": -2.7184, \"times_seen\": 47.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.062438754531652985, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.09129762246586423, \"functional effect\": -0.1117, \"times_seen\": 95.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.26110792008567435, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.10477673137078944, \"functional effect\": -0.1155, \"times_seen\": 92.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.04671147159311297, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.09030776289302542, \"functional effect\": -0.3215, \"times_seen\": 55.0}, {\"site\": 1225, \"wildtype\": \"V\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06629227926715599, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08350405497345348, \"functional effect\": -0.723, \"times_seen\": 45.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.030402509911098635, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08929262643242328, \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.034262790339491984, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08953187044240986, \"functional effect\": -0.2766, \"times_seen\": 98.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.01343995759699044, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.0866199043022126, \"functional effect\": 0.2572, \"times_seen\": 2.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -1.1841176934789912, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.03847765406971526, \"functional effect\": -0.1168, \"times_seen\": 41.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.010116117845331785, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08681969884510471, \"functional effect\": -1.5001, \"times_seen\": 1.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.1477090713188635, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.07892210657801628, \"functional effect\": 0.0645, \"times_seen\": 57.0}, {\"site\": 1226, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.016604046650683348, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08844267020606368, \"functional effect\": -0.2728, \"times_seen\": 81.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.01762642590052977, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08636891165783439, \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.025016274099241946, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08592763940778748, \"functional effect\": -0.0708, \"times_seen\": 16.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.03543884036839526, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08960488440866157, \"functional effect\": -0.0254, \"times_seen\": 14.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.039851384921914375, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08504858016665731, \"functional effect\": -0.0927, \"times_seen\": 43.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.21114795736728903, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.07552690031583897, \"functional effect\": -0.0999, \"times_seen\": 48.0}, {\"site\": 1227, \"wildtype\": \"V\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.022762852375205735, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.08606195920790094, \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.055542256667150305, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.09086223499999206, \"functional effect\": 0.1554, \"times_seen\": 49.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.9196538909339187, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.04621895512842064, \"functional effect\": -0.5252, \"times_seen\": 53.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.008271563114153755, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.08793332970496073, \"functional effect\": -1.7746, \"times_seen\": 17.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.019054774715500745, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.08628344391851454, \"functional effect\": 0.3093, \"times_seen\": 8.0}, {\"site\": 1228, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.010761345332690245, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08678087849178077, \"functional effect\": -0.1186, \"times_seen\": 8.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.015729784580976985, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08648253135307497, \"functional effect\": 0.0471, \"times_seen\": 4.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.00961393200216763, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08684992506172055, \"functional effect\": -0.1578, \"times_seen\": 15.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.009861146674754325, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08683504406765925, \"functional effect\": -0.1257, \"times_seen\": 2.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.017465058332136203, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.0884954692370839, \"functional effect\": -0.4748, \"times_seen\": 14.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.030714785865170777, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08931195619881337, \"functional effect\": -0.2131, \"times_seen\": 31.0}, {\"site\": 1229, \"wildtype\": \"I\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.036122330412250506, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08526869669778639, \"functional effect\": 0.0215, \"times_seen\": 40.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.006084211259580327, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08706267362721082, \"functional effect\": 0.3177, \"times_seen\": 1.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.05685652349366744, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.09094504642427037, \"functional effect\": -0.0475, \"times_seen\": 125.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"K\", \"log2 fold change IC90\": -0.009941002364050173, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08683023772938676, \"functional effect\": -1.3499, \"times_seen\": 1.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.1206983358142513, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08041363798933955, \"functional effect\": -0.0947, \"times_seen\": 26.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.039528003704160715, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08985922005269802, \"functional effect\": -0.8916, \"times_seen\": 5.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.007064546327650745, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08700353320067683, \"functional effect\": -0.1748, \"times_seen\": 52.0}, {\"site\": 1230, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.08304103116921777, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08254023266001631, \"functional effect\": 0.0275, \"times_seen\": 99.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.005980665618268126, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08706892254582484, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 7.061774864339225e-05, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08743489403135227, \"functional effect\": -0.1091, \"times_seen\": 32.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.002568719475314358, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.0872750825663673, \"functional effect\": -0.0854, \"times_seen\": 11.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 9.799505041168797e-06, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08743120820416753, \"functional effect\": -0.1194, \"times_seen\": 9.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.09106628851481165, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08208236206248959, \"functional effect\": -0.6804, \"times_seen\": 25.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.011095912814014706, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08676075594833474, \"functional effect\": -0.7067, \"times_seen\": 3.0}, {\"site\": 1231, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.01752545837772143, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08849917427669103, \"functional effect\": -2.3997, \"times_seen\": 1.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.006786462431524392, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08702030501503416, \"functional effect\": -2.6874, \"times_seen\": 2.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.011646472824280135, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08672765270191705, \"functional effect\": -2.8968, \"times_seen\": 4.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.013869994022150205, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08827522114127431, \"functional effect\": -0.1193, \"times_seen\": 71.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.10722945240829741, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08116788849690065, \"functional effect\": -0.0483, \"times_seen\": 17.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.005751293532797422, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08708276661366816, \"functional effect\": -1.224, \"times_seen\": 1.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.029161793132333618, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08568108461899185, \"functional effect\": -0.4282, \"times_seen\": 29.0}, {\"site\": 1232, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05080643087367579, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08440521302440869, \"functional effect\": -1.4152, \"times_seen\": 8.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.010032730009396423, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.08682471717249184, \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.5175440732343388, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.1251583474080514, \"functional effect\": -0.4074, \"times_seen\": 50.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.010076759223235325, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.08804342660878843, \"functional effect\": -1.1882, \"times_seen\": 3.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.580688475897588, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.05846000936329184, \"functional effect\": -0.4697, \"times_seen\": 55.0}, {\"site\": 1233, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00629660792761458, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.0870498570165423, \"functional effect\": -1.3228, \"times_seen\": 57.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.0034042614276156144, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08722455152663326, \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.03144394151690283, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08554565587741453, \"functional effect\": 0.0143, \"times_seen\": 86.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.009352982287052359, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.0879992677132318, \"functional effect\": -1.6031, \"times_seen\": 30.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.11060408244876874, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08097824932762027, \"functional effect\": -0.0706, \"times_seen\": 29.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0031165457416829283, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08724194839399188, \"functional effect\": -1.1254, \"times_seen\": 1.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.5366282862436713, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.12682496193559997, \"functional effect\": -0.4804, \"times_seen\": 61.0}, {\"site\": 1234, \"wildtype\": \"M\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.20791354367351042, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.07569641589121273, \"functional effect\": -0.032, \"times_seen\": 81.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.03935585174442794, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.0850777974514116, \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.05780974295686266, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.08399647547747117, \"functional effect\": -0.0204, \"times_seen\": 38.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.24964873328944215, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.07353799298972998, \"functional effect\": -0.004, \"times_seen\": 106.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"N\", \"log2 fold change IC90\": -3.9446671715046504, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.005678065373883616, \"functional effect\": -1.0371, \"times_seen\": 69.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.045244311087817866, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.08473125425253253, \"functional effect\": 0.0467, \"times_seen\": 38.0}, {\"site\": 1235, \"wildtype\": \"T\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.010548397216855144, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08679368867547188, \"functional effect\": -0.8685, \"times_seen\": 5.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.056473840295581876, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.09092092592425455, \"functional effect\": -0.1208, \"times_seen\": 55.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.013918683350815402, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08659116621232114, \"functional effect\": -1.3003, \"times_seen\": 4.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.1069603531075912, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08118302978359444, \"functional effect\": -0.2297, \"times_seen\": 60.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -1.4185048574969839, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.03270777630475383, \"functional effect\": -0.5828, \"times_seen\": 49.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.009182473666380194, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.0868759026431989, \"functional effect\": -0.3604, \"times_seen\": 31.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 2.3915404987420663, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.45876360407978795, \"functional effect\": -1.0785, \"times_seen\": 21.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -1.0441976364080974, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.04239637452420003, \"functional effect\": 0.0624, \"times_seen\": 114.0}, {\"site\": 1236, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.038560063292462754, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08512473918402891, \"functional effect\": -0.2845, \"times_seen\": 3.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0029742564537960556, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08725055326649753, \"functional effect\": -2.0316, \"times_seen\": 3.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.00773698360886485, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08696299047654926, \"functional effect\": -0.6744, \"times_seen\": 9.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.1266868355824942, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.080080539884836, \"functional effect\": -0.1106, \"times_seen\": 25.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.09754124601372846, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.09354624747076873, \"functional effect\": -0.5082, \"times_seen\": 16.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.003584369762773412, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08764810538937017, \"functional effect\": -1.4729, \"times_seen\": 32.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.0194771426011998, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08625818700653283, \"functional effect\": -1.1017, \"times_seen\": 14.0}, {\"site\": 1237, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.06370357997347258, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.09137769911858182, \"functional effect\": -0.9946, \"times_seen\": 28.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.032943983839025706, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08545675599746129, \"functional effect\": -1.7553, \"times_seen\": 4.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.01024885923246784, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08681171099128857, \"functional effect\": 0.1308, \"times_seen\": 9.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 1.9342226069413668, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.33413544885975643, \"functional effect\": -0.2409, \"times_seen\": 22.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.004588002320415144, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08715301255409982, \"functional effect\": -2.1346, \"times_seen\": 1.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.015291801452939117, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08650879029119005, \"functional effect\": -1.4508, \"times_seen\": 10.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01188852169711952, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08671310314772525, \"functional effect\": -0.5981, \"times_seen\": 14.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.0036234775469210214, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08721129884708931, \"functional effect\": -0.7344, \"times_seen\": 1.0}, {\"site\": 1238, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -1.4981885973223046, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.03095022588597369, \"functional effect\": -0.7287, \"times_seen\": 76.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.002575873365598961, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08727464979658604, \"functional effect\": -0.0966, \"times_seen\": 8.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.0005299745663454603, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08746273789879178, \"functional effect\": 0.1894, \"times_seen\": 1.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.009848267748543115, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08683581924681016, \"functional effect\": -0.2464, \"times_seen\": 10.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.4394393216000582, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.11856266347408298, \"functional effect\": -0.1266, \"times_seen\": 30.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": 0.042883528554239055, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.09006846439300824, \"functional effect\": 0.0166, \"times_seen\": 66.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.006431293121146827, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08782123539560686, \"functional effect\": 0.1954, \"times_seen\": 1.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.9355756037474134, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.16722447836494364, \"functional effect\": -0.3422, \"times_seen\": 64.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": 0.015380195453480378, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08836767530626728, \"functional effect\": 0.1987, \"times_seen\": 64.0}, {\"site\": 1239, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.1502997672608164, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.09703049976200433, \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.01973401372017597, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08863475733600189, \"functional effect\": -1.052, \"times_seen\": 1.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.006385628535669004, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08704448582449742, \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.11547885485488621, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.09471660635896194, \"functional effect\": -0.1029, \"times_seen\": 41.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.000748650032414464, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08738525619776505, \"functional effect\": -0.3107, \"times_seen\": 1.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.4461772468050795, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.06417277138795922, \"functional effect\": -0.8646, \"times_seen\": 24.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.028844050274234288, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08569995731915576, \"functional effect\": -0.1091, \"times_seen\": 7.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.2037148258637465, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.10069033901968556, \"functional effect\": -0.324, \"times_seen\": 15.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.18415289177481448, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.09933426305688968, \"functional effect\": -0.3527, \"times_seen\": 53.0}, {\"site\": 1240, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.030079503786475337, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08562659947934811, \"functional effect\": -0.5323, \"times_seen\": 48.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.008222367379693209, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08693373736126704, \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.006499154096073821, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08782536639671944, \"functional effect\": -0.1396, \"times_seen\": 30.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.022180386046506302, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08609671243891087, \"functional effect\": 0.0979, \"times_seen\": 11.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"M\", \"log2 fold change IC90\": 0.02773856343903846, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08912789910577741, \"functional effect\": 0.1033, \"times_seen\": 9.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.4397517895854638, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.06445922069725296, \"functional effect\": -0.8224, \"times_seen\": 56.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"Q\", \"log2 fold change IC90\": -0.015889248508406586, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08647297279663979, \"functional effect\": -0.5007, \"times_seen\": 3.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.006390704156254838, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08704417958929563, \"functional effect\": 0.2253, \"times_seen\": 1.0}, {\"site\": 1241, \"wildtype\": \"L\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.039694948052332577, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08505780280528423, \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.013258769850064635, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08663078355973276, \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.01275930620242574, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08666078048679154, \"functional effect\": -0.2488, \"times_seen\": 37.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.013627554591628335, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08660864164668296, \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"M\", \"log2 fold change IC90\": -1.2961905523199861, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.035601745690007056, \"functional effect\": 0.0314, \"times_seen\": 28.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"N\", \"log2 fold change IC90\": -0.8698744521736607, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.047841548418959635, \"functional effect\": -0.0857, \"times_seen\": 57.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0374131763455988, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08972759312290095, \"functional effect\": -0.6612, \"times_seen\": 4.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.03778328859661084, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08975061499563475, \"functional effect\": -0.0745, \"times_seen\": 79.0}, {\"site\": 1242, \"wildtype\": \"K\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.08045290279070826, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08268843892921285, \"functional effect\": -0.2072, \"times_seen\": 14.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": -0.003569295581610512, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.08721457422280454, \"functional effect\": 0.1697, \"times_seen\": 6.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.001657190087694402, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.08753110153640271, \"functional effect\": 0.1369, \"times_seen\": 1.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.10184115949188216, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.09382547543561749, \"functional effect\": -0.1513, \"times_seen\": 72.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.15536467526689082, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.07850441875533931, \"functional effect\": -0.2387, \"times_seen\": 105.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.35656201169234825, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.1119436313182887, \"functional effect\": -0.0637, \"times_seen\": 71.0}, {\"site\": 1243, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": 0.04037153822674604, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.08991177552433642, \"functional effect\": -0.2773, \"times_seen\": 68.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.0011654280191475028, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08736001524945157, \"functional effect\": -0.5813, \"times_seen\": 1.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": -4.40773106521918e-05, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08742794318487947, \"functional effect\": -1.9998, \"times_seen\": 1.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": -0.049430519044417955, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08448574946799113, \"functional effect\": -0.3644, \"times_seen\": 62.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.016201341961513786, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08841798632858608, \"functional effect\": -0.8924, \"times_seen\": 2.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.06681225680803918, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08347396378433362, \"functional effect\": -0.138, \"times_seen\": 24.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.04187519600512551, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.0900055354777555, \"functional effect\": -0.551, \"times_seen\": 31.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": 1.207270569022085, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.20187762374901286, \"functional effect\": -0.3998, \"times_seen\": 43.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": 0.45060832208422696, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.11948410950672038, \"functional effect\": -0.3368, \"times_seen\": 26.0}, {\"site\": 1244, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006855407658964395, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08701614648450999, \"functional effect\": -0.815, \"times_seen\": 37.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.005929583696420804, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08707200547500339, \"functional effect\": -0.4376, \"times_seen\": 1.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.012297331137572302, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08817904591321934, \"functional effect\": 0.2266, \"times_seen\": 1.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.20487677139146562, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.10077146761094442, \"functional effect\": -0.1572, \"times_seen\": 69.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": -0.026900343067053516, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08581549655786104, \"functional effect\": -0.5566, \"times_seen\": 16.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.01470902766392701, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08654374240371109, \"functional effect\": -0.0698, \"times_seen\": 28.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.3691064651943021, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.06769419254413488, \"functional effect\": -0.342, \"times_seen\": 32.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0008074341640027179, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08747956037969323, \"functional effect\": -0.321, \"times_seen\": 16.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.1355170735513475, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.07959189151331485, \"functional effect\": -0.3538, \"times_seen\": 29.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.05435412473952221, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08419790935154578, \"functional effect\": -0.1295, \"times_seen\": 44.0}, {\"site\": 1245, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05851447419107619, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08395545469160569, \"functional effect\": -0.4627, \"times_seen\": 85.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.02040698237423374, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08867611211009323, \"functional effect\": -0.7342, \"times_seen\": 2.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.050115012829176526, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.0844456742947322, \"functional effect\": -0.005, \"times_seen\": 26.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.05167592837590912, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08435435819471407, \"functional effect\": -0.0657, \"times_seen\": 36.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.04141045503519624, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.0899765463136676, \"functional effect\": -0.1038, \"times_seen\": 92.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": 0.6673059363061596, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.13884896061023236, \"functional effect\": -0.219, \"times_seen\": 45.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.0262552458810558, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08585387730535697, \"functional effect\": 0.2124, \"times_seen\": 30.0}, {\"site\": 1246, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": 0.004074580668991658, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08767789225108527, \"functional effect\": 0.096, \"times_seen\": 30.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.010072456957027517, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.08682232634601493, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.011141029742138481, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.08810839986437992, \"functional effect\": -0.3928, \"times_seen\": 2.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.6927407536277101, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.14131858361976835, \"functional effect\": 0.0678, \"times_seen\": 122.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"G\", \"log2 fold change IC90\": -1.3502193401209186, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.034293120685745006, \"functional effect\": -0.4042, \"times_seen\": 11.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.7177071094203272, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.05316332826537172, \"functional effect\": -0.086, \"times_seen\": 26.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.08811263229539071, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.09293687714684226, \"functional effect\": 0.0299, \"times_seen\": 99.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.017825546020919323, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.08851758445356028, \"functional effect\": -0.3167, \"times_seen\": 41.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.14258248317391942, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.07920305358883319, \"functional effect\": -0.0876, \"times_seen\": 45.0}, {\"site\": 1247, \"wildtype\": \"C\", \"mutant\": \"Y\", \"log2 fold change IC90\": -1.4334979971300628, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.03236962246162586, \"functional effect\": -0.0012, \"times_seen\": 125.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.018775281482963684, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08857587533556129, \"functional effect\": -0.2543, \"times_seen\": 2.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"A\", \"log2 fold change IC90\": -0.021083928635241195, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08616217135966432, \"functional effect\": 0.0212, \"times_seen\": 9.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.00945653877583831, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08685940061629376, \"functional effect\": 0.4135, \"times_seen\": 3.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"D\", \"log2 fold change IC90\": -0.027970131798083796, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08575188614851614, \"functional effect\": 0.1186, \"times_seen\": 40.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"E\", \"log2 fold change IC90\": 0.3004584542527597, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.10767392316940215, \"functional effect\": 0.0622, \"times_seen\": 55.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.0029536485763104188, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08725179958779433, \"functional effect\": 0.1906, \"times_seen\": 1.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.05789828916884548, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.09101074128022453, \"functional effect\": 0.2094, \"times_seen\": 63.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"S\", \"log2 fold change IC90\": -0.01702458572068195, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08640494915952819, \"functional effect\": 0.3219, \"times_seen\": 18.0}, {\"site\": 1248, \"wildtype\": \"G\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.01573614699786464, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08648214995805449, \"functional effect\": 0.0905, \"times_seen\": 67.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"*\", \"log2 fold change IC90\": -0.028707777123837624, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08570805269234556, \"functional effect\": -0.0346, \"times_seen\": 49.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"-\", \"log2 fold change IC90\": 0.010925457518194109, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08809523540190718, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"A\", \"log2 fold change IC90\": 0.00860670709287566, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08795375935117712, \"functional effect\": -0.0001, \"times_seen\": 81.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"C\", \"log2 fold change IC90\": -0.7849958816137331, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.050740672991310964, \"functional effect\": 0.3963, \"times_seen\": 143.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"D\", \"log2 fold change IC90\": 0.04443210578582167, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.09016519506258469, \"functional effect\": 0.1111, \"times_seen\": 45.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"E\", \"log2 fold change IC90\": -0.06753830439339688, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08343196542678284, \"functional effect\": -0.0168, \"times_seen\": 30.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"F\", \"log2 fold change IC90\": 0.0041596428837454924, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.0876830619476318, \"functional effect\": 0.397, \"times_seen\": 141.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"G\", \"log2 fold change IC90\": 0.25187095678532917, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.10410803346135465, \"functional effect\": -0.4074, \"times_seen\": 94.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"H\", \"log2 fold change IC90\": 0.2012256392951324, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.10051676044934797, \"functional effect\": 0.2924, \"times_seen\": 41.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"I\", \"log2 fold change IC90\": -0.09319904367176145, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08196110826883232, \"functional effect\": 0.4224, \"times_seen\": 50.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"K\", \"log2 fold change IC90\": -1.5940597139486359, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.02896034566328649, \"functional effect\": 0.1965, \"times_seen\": 40.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.2250142057708731, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.07480446213294302, \"functional effect\": 0.3611, \"times_seen\": 101.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"M\", \"log2 fold change IC90\": -0.020532410922156775, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08619511598520821, \"functional effect\": 0.2764, \"times_seen\": 31.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"N\", \"log2 fold change IC90\": 0.020911489459742236, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08870712736200571, \"functional effect\": 0.397, \"times_seen\": 36.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"P\", \"log2 fold change IC90\": -0.002105149643258157, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08730313048706982, \"functional effect\": 0.2155, \"times_seen\": 158.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02466116958850647, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08893798417888676, \"functional effect\": 0.3237, \"times_seen\": 25.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"R\", \"log2 fold change IC90\": 0.07336251326332068, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.09199153104270684, \"functional effect\": 0.2863, \"times_seen\": 95.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"T\", \"log2 fold change IC90\": -0.021170190181608615, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08615701970963964, \"functional effect\": -0.2164, \"times_seen\": 136.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"V\", \"log2 fold change IC90\": -0.21228055292094627, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.07546763078176645, \"functional effect\": 0.3255, \"times_seen\": 99.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.004265169257796596, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08717251703799314, \"functional effect\": 0.2297, \"times_seen\": 29.0}, {\"site\": 1249, \"wildtype\": \"S\", \"mutant\": \"Y\", \"log2 fold change IC90\": -2.8266271102679075, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.012324348860282459, \"functional effect\": 0.4444, \"times_seen\": 126.0}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"*\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.08743061432976482, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"L\", \"log2 fold change IC90\": -0.015526262680168459, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.08649473235898793, \"functional effect\": 0.3678, \"times_seen\": 5.0}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"R\", \"log2 fold change IC90\": -0.0050851929582774414, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.08712298250969111, \"functional effect\": 0.397, \"times_seen\": 62.0}, {\"site\": 1250, \"wildtype\": \"*\", \"mutant\": \"W\", \"log2 fold change IC90\": -0.016405197884991514, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.08644205309554849, \"functional effect\": 0.397, \"times_seen\": 2.0}, {\"site\": 1, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": null, \"functional effect\": -2.3068, \"times_seen\": null}, {\"site\": 2, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": null, \"functional effect\": -0.206, \"times_seen\": null}, {\"site\": 6, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 6, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": null, \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -3.1225, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -3.1479, \"times_seen\": null}, {\"site\": 7, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -0.7825, \"times_seen\": null}, {\"site\": 8, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": null, \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 8, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": null, \"functional effect\": -2.7606, \"times_seen\": null}, {\"site\": 9, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 10, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": null, \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 11, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": null, \"functional effect\": -1.9748, \"times_seen\": null}, {\"site\": 12, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": null, \"functional effect\": -3.2561, \"times_seen\": null}, {\"site\": 12, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": null, \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 13, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": null, \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 13, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": null, \"functional effect\": -0.2003, \"times_seen\": null}, {\"site\": 13, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": null, \"functional effect\": 0.4072, \"times_seen\": null}, {\"site\": 14, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": null, \"functional effect\": -2.7736, \"times_seen\": null}, {\"site\": 15, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": null, \"functional effect\": -3.2502, \"times_seen\": null}, {\"site\": 15, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": null, \"functional effect\": 0.6185, \"times_seen\": null}, {\"site\": 16, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": null, \"functional effect\": 0.0858, \"times_seen\": null}, {\"site\": 16, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 17, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": null, \"functional effect\": -0.8797, \"times_seen\": null}, {\"site\": 22, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": null, \"functional effect\": 0.0432, \"times_seen\": null}, {\"site\": 23, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": null, \"functional effect\": -1.1418, \"times_seen\": null}, {\"site\": 26, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": null, \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 27, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": null, \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 28, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": null, \"functional effect\": -2.7365, \"times_seen\": null}, {\"site\": 28, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": null, \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 28, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 31, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": null, \"functional effect\": 0.1285, \"times_seen\": null}, {\"site\": 31, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": null, \"functional effect\": -3.1061, \"times_seen\": null}, {\"site\": 31, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 32, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 32, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": null, \"functional effect\": -2.098, \"times_seen\": null}, {\"site\": 33, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 34, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 34, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": null, \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -0.7648, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -1.9509, \"times_seen\": null}, {\"site\": 35, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 36, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 36, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": null, \"functional effect\": -1.2668, \"times_seen\": null}, {\"site\": 37, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 37, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": null, \"functional effect\": -2.2193, \"times_seen\": null}, {\"site\": 37, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": null, \"functional effect\": -3.1105, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -2.77, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -1.4117, \"times_seen\": null}, {\"site\": 38, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 39, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 40, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 40, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": null, \"functional effect\": -0.4397, \"times_seen\": null}, {\"site\": 41, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 41, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 42, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 42, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": null, \"functional effect\": -3.3265, \"times_seen\": null}, {\"site\": 43, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": null, \"functional effect\": -3.1126, \"times_seen\": null}, {\"site\": 43, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": null, \"functional effect\": -2.939, \"times_seen\": null}, {\"site\": 43, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": null, \"functional effect\": -2.9977, \"times_seen\": null}, {\"site\": 44, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": null, \"functional effect\": 0.0669, \"times_seen\": null}, {\"site\": 45, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": null, \"functional effect\": 0.1193, \"times_seen\": null}, {\"site\": 46, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": null, \"functional effect\": -0.3882, \"times_seen\": null}, {\"site\": 47, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": null, \"functional effect\": -3.0776, \"times_seen\": null}, {\"site\": 47, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": null, \"functional effect\": -1.3525, \"times_seen\": null}, {\"site\": 48, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": null, \"functional effect\": -2.8194, \"times_seen\": null}, {\"site\": 49, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": null, \"functional effect\": -1.9489, \"times_seen\": null}, {\"site\": 49, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": null, \"functional effect\": -1.1338, \"times_seen\": null}, {\"site\": 49, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": null, \"functional effect\": -0.3197, \"times_seen\": null}, {\"site\": 51, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": null, \"functional effect\": -3.205, \"times_seen\": null}, {\"site\": 52, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": null, \"functional effect\": -2.8375, \"times_seen\": null}, {\"site\": 53, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": null, \"functional effect\": -2.9837, \"times_seen\": null}, {\"site\": 54, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": null, \"functional effect\": -0.3841, \"times_seen\": null}, {\"site\": 54, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": null, \"functional effect\": -0.3237, \"times_seen\": null}, {\"site\": 55, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": null, \"functional effect\": -2.1941, \"times_seen\": null}, {\"site\": 55, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": null, \"functional effect\": -2.7433, \"times_seen\": null}, {\"site\": 55, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 56, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": null, \"functional effect\": -2.7355, \"times_seen\": null}, {\"site\": 57, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": null, \"functional effect\": -0.9319, \"times_seen\": null}, {\"site\": 57, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": null, \"functional effect\": -2.3902, \"times_seen\": null}, {\"site\": 58, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": null, \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 58, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": null, \"functional effect\": -2.9906, \"times_seen\": null}, {\"site\": 58, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": null, \"functional effect\": 0.0307, \"times_seen\": null}, {\"site\": 60, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": null, \"functional effect\": -2.3603, \"times_seen\": null}, {\"site\": 63, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 65, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": null, \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 66, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 68, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": null, \"functional effect\": -0.4954, \"times_seen\": null}, {\"site\": 69, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": null, \"functional effect\": -0.1804, \"times_seen\": null}, {\"site\": 71, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": null, \"functional effect\": -0.0436, \"times_seen\": null}, {\"site\": 75, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": null, \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 75, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 76, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": null, \"functional effect\": 0.0957, \"times_seen\": null}, {\"site\": 77, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": null, \"functional effect\": 0.0182, \"times_seen\": null}, {\"site\": 77, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": null, \"functional effect\": 0.4525, \"times_seen\": null}, {\"site\": 77, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": null, \"functional effect\": -1.6337, \"times_seen\": null}, {\"site\": 79, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": null, \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 81, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": null, \"functional effect\": -0.1781, \"times_seen\": null}, {\"site\": 81, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 81, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": null, \"functional effect\": -3.251, \"times_seen\": null}, {\"site\": 83, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": null, \"functional effect\": -0.4456, \"times_seen\": null}, {\"site\": 87, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": null, \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 87, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": null, \"functional effect\": -1.9226, \"times_seen\": null}, {\"site\": 87, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": null, \"functional effect\": -2.3548, \"times_seen\": null}, {\"site\": 88, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": null, \"functional effect\": -3.002, \"times_seen\": null}, {\"site\": 88, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": null, \"functional effect\": -0.2691, \"times_seen\": null}, {\"site\": 89, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": null, \"functional effect\": -2.5509, \"times_seen\": null}, {\"site\": 89, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": null, \"functional effect\": -3.0806, \"times_seen\": null}, {\"site\": 89, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": null, \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 90, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": null, \"functional effect\": -1.1825, \"times_seen\": null}, {\"site\": 91, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": null, \"functional effect\": -3.2479, \"times_seen\": null}, {\"site\": 92, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 95, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": null, \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 97, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": null, \"functional effect\": -0.6425, \"times_seen\": null}, {\"site\": 97, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": null, \"functional effect\": -0.4147, \"times_seen\": null}, {\"site\": 98, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": null, \"functional effect\": -0.0746, \"times_seen\": null}, {\"site\": 98, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 99, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 99, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": null, \"functional effect\": -0.1396, \"times_seen\": null}, {\"site\": 100, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 100, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": null, \"functional effect\": -0.4304, \"times_seen\": null}, {\"site\": 101, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 101, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": null, \"functional effect\": -1.5467, \"times_seen\": null}, {\"site\": 102, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 103, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 104, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 104, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": null, \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 105, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 105, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": null, \"functional effect\": -2.1019, \"times_seen\": null}, {\"site\": 107, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 107, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": null, \"functional effect\": -3.0375, \"times_seen\": null}, {\"site\": 108, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 108, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": null, \"functional effect\": -1.0578, \"times_seen\": null}, {\"site\": 109, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 110, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 115, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": null, \"functional effect\": -3.2758, \"times_seen\": null}, {\"site\": 116, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": null, \"functional effect\": -2.9821, \"times_seen\": null}, {\"site\": 116, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": null, \"functional effect\": -0.8778, \"times_seen\": null}, {\"site\": 117, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": null, \"functional effect\": -1.067, \"times_seen\": null}, {\"site\": 117, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": null, \"functional effect\": -0.835, \"times_seen\": null}, {\"site\": 118, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": null, \"functional effect\": -0.481, \"times_seen\": null}, {\"site\": 119, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": null, \"functional effect\": -2.8939, \"times_seen\": null}, {\"site\": 120, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": null, \"functional effect\": 0.3319, \"times_seen\": null}, {\"site\": 121, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": null, \"functional effect\": -1.6932, \"times_seen\": null}, {\"site\": 125, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": null, \"functional effect\": -0.0781, \"times_seen\": null}, {\"site\": 125, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": null, \"functional effect\": 0.2259, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": 0.9989, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": -1.4896, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": -1.743, \"times_seen\": null}, {\"site\": 126, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": -0.388, \"times_seen\": null}, {\"site\": 127, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": null, \"functional effect\": -2.9735, \"times_seen\": null}, {\"site\": 127, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 129, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": null, \"functional effect\": -3.2644, \"times_seen\": null}, {\"site\": 129, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": null, \"functional effect\": -2.2294, \"times_seen\": null}, {\"site\": 129, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": null, \"functional effect\": -3.2541, \"times_seen\": null}, {\"site\": 130, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": null, \"functional effect\": -2.9703, \"times_seen\": null}, {\"site\": 131, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": null, \"functional effect\": -3.2642, \"times_seen\": null}, {\"site\": 132, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": null, \"functional effect\": -0.5534, \"times_seen\": null}, {\"site\": 133, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 134, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": null, \"functional effect\": 0.2867, \"times_seen\": null}, {\"site\": 135, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 140, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": null, \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 142, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": null, \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 142, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": null, \"functional effect\": 0.8951, \"times_seen\": null}, {\"site\": 142, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": null, \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 143, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": null, \"functional effect\": -0.2116, \"times_seen\": null}, {\"site\": 144, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": null, \"functional effect\": 0.2256, \"times_seen\": null}, {\"site\": 145, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 147, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": null, \"functional effect\": -0.7731, \"times_seen\": null}, {\"site\": 149, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": null, \"functional effect\": -2.9301, \"times_seen\": null}, {\"site\": 150, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": null, \"functional effect\": -3.1878, \"times_seen\": null}, {\"site\": 150, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": null, \"functional effect\": -0.2891, \"times_seen\": null}, {\"site\": 153, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": null, \"functional effect\": 0.27, \"times_seen\": null}, {\"site\": 154, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": null, \"functional effect\": -0.0379, \"times_seen\": null}, {\"site\": 155, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 155, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 157, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": null, \"functional effect\": -2.4732, \"times_seen\": null}, {\"site\": 157, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 160, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": null, \"functional effect\": -0.8719, \"times_seen\": null}, {\"site\": 161, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": null, \"functional effect\": -3.0134, \"times_seen\": null}, {\"site\": 161, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 161, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": null, \"functional effect\": -3.0054, \"times_seen\": null}, {\"site\": 162, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": null, \"functional effect\": -0.1392, \"times_seen\": null}, {\"site\": 163, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": null, \"functional effect\": -0.2547, \"times_seen\": null}, {\"site\": 163, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": null, \"functional effect\": -0.8997, \"times_seen\": null}, {\"site\": 164, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": null, \"functional effect\": -3.0021, \"times_seen\": null}, {\"site\": 165, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": null, \"functional effect\": -0.3584, \"times_seen\": null}, {\"site\": 168, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": null, \"functional effect\": -1.0772, \"times_seen\": null}, {\"site\": 168, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": null, \"functional effect\": 0.06, \"times_seen\": null}, {\"site\": 170, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 171, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": null, \"functional effect\": -0.5502, \"times_seen\": null}, {\"site\": 173, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": null, \"functional effect\": -2.3457, \"times_seen\": null}, {\"site\": 174, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": null, \"functional effect\": -3.2847, \"times_seen\": null}, {\"site\": 174, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": null, \"functional effect\": 0.3709, \"times_seen\": null}, {\"site\": 175, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": null, \"functional effect\": -2.3131, \"times_seen\": null}, {\"site\": 177, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": null, \"functional effect\": -3.2884, \"times_seen\": null}, {\"site\": 177, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": null, \"functional effect\": -0.3944, \"times_seen\": null}, {\"site\": 178, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 179, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 179, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": null, \"functional effect\": 0.2267, \"times_seen\": null}, {\"site\": 180, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 181, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 182, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 183, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": null, \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 183, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 184, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 184, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": null, \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 184, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": null, \"functional effect\": -0.8023, \"times_seen\": null}, {\"site\": 185, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 185, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 186, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 186, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": null, \"functional effect\": -2.487, \"times_seen\": null}, {\"site\": 187, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 187, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": null, \"functional effect\": -0.7, \"times_seen\": null}, {\"site\": 188, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 188, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": null, \"functional effect\": -3.0012, \"times_seen\": null}, {\"site\": 188, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": null, \"functional effect\": -1.0815, \"times_seen\": null}, {\"site\": 189, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 189, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": null, \"functional effect\": -2.9593, \"times_seen\": null}, {\"site\": 190, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 190, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": null, \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 190, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 191, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 191, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 193, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": null, \"functional effect\": -2.9276, \"times_seen\": null}, {\"site\": 195, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": null, \"functional effect\": -2.8839, \"times_seen\": null}, {\"site\": 196, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": null, \"functional effect\": -0.6135, \"times_seen\": null}, {\"site\": 197, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": null, \"functional effect\": -0.5056, \"times_seen\": null}, {\"site\": 198, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 199, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": null, \"functional effect\": -2.2239, \"times_seen\": null}, {\"site\": 200, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": null, \"functional effect\": -0.681, \"times_seen\": null}, {\"site\": 201, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 202, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": null, \"functional effect\": -0.3132, \"times_seen\": null}, {\"site\": 203, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": null, \"functional effect\": -0.2688, \"times_seen\": null}, {\"site\": 204, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": null, \"functional effect\": 0.2366, \"times_seen\": null}, {\"site\": 205, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": null, \"functional effect\": -3.1276, \"times_seen\": null}, {\"site\": 208, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": null, \"functional effect\": -3.0402, \"times_seen\": null}, {\"site\": 208, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": null, \"functional effect\": -0.031, \"times_seen\": null}, {\"site\": 209, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": null, \"functional effect\": -3.0075, \"times_seen\": null}, {\"site\": 212, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 213, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": null, \"functional effect\": -0.3526, \"times_seen\": null}, {\"site\": 214, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 215, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": null, \"functional effect\": -2.7657, \"times_seen\": null}, {\"site\": 215, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 216, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 216, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": null, \"functional effect\": 0.0321, \"times_seen\": null}, {\"site\": 217, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 217, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": null, \"functional effect\": -1.2951, \"times_seen\": null}, {\"site\": 218, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 219, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -2.4924, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -2.5797, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -0.9401, \"times_seen\": null}, {\"site\": 220, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -3.2667, \"times_seen\": null}, {\"site\": 221, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": null, \"functional effect\": -2.5387, \"times_seen\": null}, {\"site\": 221, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 221, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": null, \"functional effect\": -0.4872, \"times_seen\": null}, {\"site\": 222, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 222, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": null, \"functional effect\": -2.138, \"times_seen\": null}, {\"site\": 223, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 224, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": null, \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 224, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": null, \"functional effect\": -0.0935, \"times_seen\": null}, {\"site\": 224, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": null, \"functional effect\": -3.0983, \"times_seen\": null}, {\"site\": 226, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": null, \"functional effect\": 0.0504, \"times_seen\": null}, {\"site\": 226, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": null, \"functional effect\": -1.7349, \"times_seen\": null}, {\"site\": 228, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": null, \"functional effect\": -0.0682, \"times_seen\": null}, {\"site\": 229, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 230, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": null, \"functional effect\": -0.229, \"times_seen\": null}, {\"site\": 230, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": null, \"functional effect\": 0.0646, \"times_seen\": null}, {\"site\": 232, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": null, \"functional effect\": -2.8017, \"times_seen\": null}, {\"site\": 234, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": null, \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 235, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": null, \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 235, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": null, \"functional effect\": 0.0113, \"times_seen\": null}, {\"site\": 235, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": null, \"functional effect\": -0.1558, \"times_seen\": null}, {\"site\": 236, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": null, \"functional effect\": -2.1075, \"times_seen\": null}, {\"site\": 238, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": null, \"functional effect\": -0.0438, \"times_seen\": null}, {\"site\": 240, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": null, \"functional effect\": 0.0181, \"times_seen\": null}, {\"site\": 241, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": null, \"functional effect\": 0.1266, \"times_seen\": null}, {\"site\": 243, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": null, \"functional effect\": 0.0263, \"times_seen\": null}, {\"site\": 245, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": null, \"functional effect\": -0.3224, \"times_seen\": null}, {\"site\": 248, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 249, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": null, \"functional effect\": -0.3516, \"times_seen\": null}, {\"site\": 250, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": null, \"functional effect\": -2.9867, \"times_seen\": null}, {\"site\": 251, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": null, \"functional effect\": -2.8802, \"times_seen\": null}, {\"site\": 251, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": null, \"functional effect\": -1.236, \"times_seen\": null}, {\"site\": 252, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 253, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 257, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": null, \"functional effect\": -0.0857, \"times_seen\": null}, {\"site\": 257, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": null, \"functional effect\": 0.0593, \"times_seen\": null}, {\"site\": 258, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": null, \"functional effect\": -1.6178, \"times_seen\": null}, {\"site\": 259, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": null, \"functional effect\": 1.1621, \"times_seen\": null}, {\"site\": 261, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": null, \"functional effect\": 0.0343, \"times_seen\": null}, {\"site\": 262, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 263, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": null, \"functional effect\": -3.1313, \"times_seen\": null}, {\"site\": 263, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": null, \"functional effect\": -2.7898, \"times_seen\": null}, {\"site\": 264, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": null, \"functional effect\": -0.5584, \"times_seen\": null}, {\"site\": 264, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": null, \"functional effect\": -2.6471, \"times_seen\": null}, {\"site\": 265, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 266, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": null, \"functional effect\": 0.0884, \"times_seen\": null}, {\"site\": 266, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": null, \"functional effect\": 0.7108, \"times_seen\": null}, {\"site\": 267, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": null, \"functional effect\": -2.2507, \"times_seen\": null}, {\"site\": 267, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": null, \"functional effect\": -2.5835, \"times_seen\": null}, {\"site\": 268, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": null, \"functional effect\": -1.7877, \"times_seen\": null}, {\"site\": 268, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": null, \"functional effect\": -0.1829, \"times_seen\": null}, {\"site\": 269, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": null, \"functional effect\": 0.2025, \"times_seen\": null}, {\"site\": 269, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": null, \"functional effect\": -3.2083, \"times_seen\": null}, {\"site\": 270, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": null, \"functional effect\": -1.3479, \"times_seen\": null}, {\"site\": 270, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": null, \"functional effect\": -0.7758, \"times_seen\": null}, {\"site\": 272, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": null, \"functional effect\": -2.9369, \"times_seen\": null}, {\"site\": 272, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": null, \"functional effect\": -0.5865, \"times_seen\": null}, {\"site\": 272, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": null, \"functional effect\": -0.1679, \"times_seen\": null}, {\"site\": 274, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": null, \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 274, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": null, \"functional effect\": -0.9872, \"times_seen\": null}, {\"site\": 276, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": null, \"functional effect\": -1.0005, \"times_seen\": null}, {\"site\": 276, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": null, \"functional effect\": -2.5458, \"times_seen\": null}, {\"site\": 277, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": null, \"functional effect\": -0.92, \"times_seen\": null}, {\"site\": 278, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": null, \"functional effect\": -1.0849, \"times_seen\": null}, {\"site\": 280, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": null, \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 280, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": null, \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 280, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": null, \"functional effect\": -2.4582, \"times_seen\": null}, {\"site\": 282, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": null, \"functional effect\": -2.9946, \"times_seen\": null}, {\"site\": 283, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": null, \"functional effect\": 0.3002, \"times_seen\": null}, {\"site\": 284, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": null, \"functional effect\": -0.7471, \"times_seen\": null}, {\"site\": 286, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": null, \"functional effect\": -3.2617, \"times_seen\": null}, {\"site\": 286, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": null, \"functional effect\": -2.3127, \"times_seen\": null}, {\"site\": 287, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": null, \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 287, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": null, \"functional effect\": -1.8474, \"times_seen\": null}, {\"site\": 287, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": null, \"functional effect\": -1.9768, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": -2.8456, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": -2.9996, \"times_seen\": null}, {\"site\": 288, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 289, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": null, \"functional effect\": -2.9013, \"times_seen\": null}, {\"site\": 291, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": null, \"functional effect\": -2.6269, \"times_seen\": null}, {\"site\": 291, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": null, \"functional effect\": -3.032, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -2.9899, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -2.4632, \"times_seen\": null}, {\"site\": 292, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -3.2361, \"times_seen\": null}, {\"site\": 293, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": null, \"functional effect\": -3.268, \"times_seen\": null}, {\"site\": 293, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": null, \"functional effect\": -2.318, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -2.9573, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -1.8098, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 294, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -3.128, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -2.5392, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -1.1533, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -2.9724, \"times_seen\": null}, {\"site\": 295, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -2.5601, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": -1.2613, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": -2.7906, \"times_seen\": null}, {\"site\": 297, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": -1.4359, \"times_seen\": null}, {\"site\": 298, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": null, \"functional effect\": -2.6362, \"times_seen\": null}, {\"site\": 298, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": null, \"functional effect\": -2.7258, \"times_seen\": null}, {\"site\": 299, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": null, \"functional effect\": -2.4022, \"times_seen\": null}, {\"site\": 300, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": null, \"functional effect\": -0.1477, \"times_seen\": null}, {\"site\": 300, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": null, \"functional effect\": -0.6929, \"times_seen\": null}, {\"site\": 301, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": null, \"functional effect\": -3.2048, \"times_seen\": null}, {\"site\": 302, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": null, \"functional effect\": -1.1989, \"times_seen\": null}, {\"site\": 302, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": null, \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 302, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": null, \"functional effect\": -2.6361, \"times_seen\": null}, {\"site\": 303, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": null, \"functional effect\": -2.4926, \"times_seen\": null}, {\"site\": 304, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": null, \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 305, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": null, \"functional effect\": -2.9941, \"times_seen\": null}, {\"site\": 306, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": null, \"functional effect\": -3.0868, \"times_seen\": null}, {\"site\": 307, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": null, \"functional effect\": -2.9005, \"times_seen\": null}, {\"site\": 307, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": null, \"functional effect\": -2.8108, \"times_seen\": null}, {\"site\": 308, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": null, \"functional effect\": -2.4876, \"times_seen\": null}, {\"site\": 308, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": null, \"functional effect\": -1.6802, \"times_seen\": null}, {\"site\": 308, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": null, \"functional effect\": -3.1353, \"times_seen\": null}, {\"site\": 309, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": null, \"functional effect\": -0.0493, \"times_seen\": null}, {\"site\": 309, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": null, \"functional effect\": -1.8036, \"times_seen\": null}, {\"site\": 309, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": null, \"functional effect\": -2.144, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.7744, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -0.4934, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.4895, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.942, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.6642, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.0463, \"times_seen\": null}, {\"site\": 310, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -3.0359, \"times_seen\": null}, {\"site\": 311, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": null, \"functional effect\": -1.2648, \"times_seen\": null}, {\"site\": 311, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": null, \"functional effect\": -0.3253, \"times_seen\": null}, {\"site\": 312, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": null, \"functional effect\": -2.5656, \"times_seen\": null}, {\"site\": 312, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": null, \"functional effect\": -2.5653, \"times_seen\": null}, {\"site\": 312, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": null, \"functional effect\": -2.99, \"times_seen\": null}, {\"site\": 313, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": null, \"functional effect\": -0.2211, \"times_seen\": null}, {\"site\": 313, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": null, \"functional effect\": -0.8517, \"times_seen\": null}, {\"site\": 313, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": null, \"functional effect\": -2.6799, \"times_seen\": null}, {\"site\": 314, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": null, \"functional effect\": -2.3119, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -3.1273, \"times_seen\": null}, {\"site\": 316, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -2.9726, \"times_seen\": null}, {\"site\": 317, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": null, \"functional effect\": -1.9108, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -2.9236, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -2.8881, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -2.8281, \"times_seen\": null}, {\"site\": 319, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -3.13, \"times_seen\": null}, {\"site\": 321, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": null, \"functional effect\": -2.9699, \"times_seen\": null}, {\"site\": 321, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": null, \"functional effect\": -0.3572, \"times_seen\": null}, {\"site\": 323, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": null, \"functional effect\": -3.2614, \"times_seen\": null}, {\"site\": 323, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": null, \"functional effect\": -3.1291, \"times_seen\": null}, {\"site\": 324, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": null, \"functional effect\": -1.6056, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -2.9665, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -2.6845, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -1.2725, \"times_seen\": null}, {\"site\": 325, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -2.0587, \"times_seen\": null}, {\"site\": 326, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": null, \"functional effect\": -3.0183, \"times_seen\": null}, {\"site\": 326, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": null, \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 327, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": null, \"functional effect\": -2.5724, \"times_seen\": null}, {\"site\": 329, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": null, \"functional effect\": -0.3912, \"times_seen\": null}, {\"site\": 329, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": null, \"functional effect\": -1.7635, \"times_seen\": null}, {\"site\": 329, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": null, \"functional effect\": 0.087, \"times_seen\": null}, {\"site\": 331, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": null, \"functional effect\": -1.0289, \"times_seen\": null}, {\"site\": 333, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": null, \"functional effect\": -1.984, \"times_seen\": null}, {\"site\": 333, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": null, \"functional effect\": -2.0218, \"times_seen\": null}, {\"site\": 333, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": null, \"functional effect\": -2.8487, \"times_seen\": null}, {\"site\": 334, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": null, \"functional effect\": -0.4448, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.8826, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.9682, \"times_seen\": null}, {\"site\": 335, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.6032, \"times_seen\": null}, {\"site\": 336, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 337, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": null, \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 337, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -2.9882, \"times_seen\": null}, {\"site\": 338, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -3.0848, \"times_seen\": null}, {\"site\": 339, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 339, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": null, \"functional effect\": -2.879, \"times_seen\": null}, {\"site\": 340, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 340, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": null, \"functional effect\": -3.2684, \"times_seen\": null}, {\"site\": 340, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": null, \"functional effect\": -2.0563, \"times_seen\": null}, {\"site\": 341, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": null, \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 341, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": null, \"functional effect\": -2.5035, \"times_seen\": null}, {\"site\": 342, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": null, \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 343, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": null, \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 343, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": null, \"functional effect\": -1.4097, \"times_seen\": null}, {\"site\": 345, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": null, \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 345, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": null, \"functional effect\": -2.6967, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.9226, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.9673, \"times_seen\": null}, {\"site\": 346, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 347, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": null, \"functional effect\": -1.3334, \"times_seen\": null}, {\"site\": 347, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 347, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": null, \"functional effect\": -2.9322, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -2.1682, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -2.0452, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -3.2547, \"times_seen\": null}, {\"site\": 348, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -2.7372, \"times_seen\": null}, {\"site\": 349, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": null, \"functional effect\": -2.7571, \"times_seen\": null}, {\"site\": 349, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": null, \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 349, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 350, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": null, \"functional effect\": -2.7008, \"times_seen\": null}, {\"site\": 350, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": null, \"functional effect\": -0.759, \"times_seen\": null}, {\"site\": 351, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": null, \"functional effect\": -0.3727, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -3.0142, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -2.9914, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -2.6016, \"times_seen\": null}, {\"site\": 352, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -2.7663, \"times_seen\": null}, {\"site\": 353, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": null, \"functional effect\": -2.6337, \"times_seen\": null}, {\"site\": 354, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": null, \"functional effect\": -1.6586, \"times_seen\": null}, {\"site\": 355, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": null, \"functional effect\": -1.5589, \"times_seen\": null}, {\"site\": 355, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": null, \"functional effect\": -3.2049, \"times_seen\": null}, {\"site\": 356, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": null, \"functional effect\": -0.9389, \"times_seen\": null}, {\"site\": 357, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": null, \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -3.1294, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -3.2653, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -3.1037, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -2.8591, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -2.9714, \"times_seen\": null}, {\"site\": 358, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 359, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 359, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": null, \"functional effect\": -2.8474, \"times_seen\": null}, {\"site\": 360, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 361, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 361, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": null, \"functional effect\": -2.4825, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -2.6021, \"times_seen\": null}, {\"site\": 362, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 363, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 363, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": null, \"functional effect\": -2.9689, \"times_seen\": null}, {\"site\": 364, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 365, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": null, \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 365, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": null, \"functional effect\": -3.0169, \"times_seen\": null}, {\"site\": 365, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": null, \"functional effect\": -0.29, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": -2.996, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 366, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": -0.7909, \"times_seen\": null}, {\"site\": 367, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": null, \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 367, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": null, \"functional effect\": -2.7039, \"times_seen\": null}, {\"site\": 368, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": null, \"functional effect\": -3.1689, \"times_seen\": null}, {\"site\": 370, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": null, \"functional effect\": -0.21, \"times_seen\": null}, {\"site\": 371, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": null, \"functional effect\": 0.1515, \"times_seen\": null}, {\"site\": 371, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": null, \"functional effect\": -2.4492, \"times_seen\": null}, {\"site\": 371, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": null, \"functional effect\": -1.203, \"times_seen\": null}, {\"site\": 373, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": null, \"functional effect\": -2.9734, \"times_seen\": null}, {\"site\": 374, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 374, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": null, \"functional effect\": -0.67, \"times_seen\": null}, {\"site\": 375, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 375, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -2.9931, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -2.1907, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -3.2038, \"times_seen\": null}, {\"site\": 376, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -3.2034, \"times_seen\": null}, {\"site\": 377, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": null, \"functional effect\": -2.7142, \"times_seen\": null}, {\"site\": 377, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 378, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 378, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": null, \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 379, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 379, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": null, \"functional effect\": -1.5909, \"times_seen\": null}, {\"site\": 380, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 380, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": null, \"functional effect\": -1.8667, \"times_seen\": null}, {\"site\": 380, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": null, \"functional effect\": -1.7595, \"times_seen\": null}, {\"site\": 381, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 382, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 382, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 383, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 383, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": null, \"functional effect\": -0.8204, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -2.9459, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -3.2651, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -3.036, \"times_seen\": null}, {\"site\": 384, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -2.9934, \"times_seen\": null}, {\"site\": 385, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 385, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": null, \"functional effect\": -1.1864, \"times_seen\": null}, {\"site\": 385, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 386, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 386, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": null, \"functional effect\": -2.689, \"times_seen\": null}, {\"site\": 386, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": null, \"functional effect\": -1.8675, \"times_seen\": null}, {\"site\": 387, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 387, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": null, \"functional effect\": -3.2571, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -2.9487, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -3.0135, \"times_seen\": null}, {\"site\": 388, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -3.0351, \"times_seen\": null}, {\"site\": 389, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 389, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": null, \"functional effect\": -1.8995, \"times_seen\": null}, {\"site\": 390, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 390, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": null, \"functional effect\": -2.9133, \"times_seen\": null}, {\"site\": 391, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 392, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 392, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": null, \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 393, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": null, \"functional effect\": -2.9509, \"times_seen\": null}, {\"site\": 393, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 393, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": null, \"functional effect\": -0.0178, \"times_seen\": null}, {\"site\": 394, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 394, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": null, \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 395, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": null, \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 395, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": null, \"functional effect\": -2.8109, \"times_seen\": null}, {\"site\": 395, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": null, \"functional effect\": -3.2346, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -2.4874, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -3.131, \"times_seen\": null}, {\"site\": 396, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -3.0019, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -2.7856, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -1.7314, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -1.5979, \"times_seen\": null}, {\"site\": 397, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -2.223, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": 1.4893, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": 0.0417, \"times_seen\": null}, {\"site\": 398, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": -2.2593, \"times_seen\": null}, {\"site\": 399, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 399, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": null, \"functional effect\": -3.0507, \"times_seen\": null}, {\"site\": 400, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 400, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": null, \"functional effect\": -2.3165, \"times_seen\": null}, {\"site\": 401, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 401, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": null, \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 401, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": null, \"functional effect\": -2.8796, \"times_seen\": null}, {\"site\": 402, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -2.9827, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -2.6011, \"times_seen\": null}, {\"site\": 403, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -2.6288, \"times_seen\": null}, {\"site\": 404, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 404, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": null, \"functional effect\": -0.0389, \"times_seen\": null}, {\"site\": 405, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 406, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 407, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 407, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": null, \"functional effect\": -1.5536, \"times_seen\": null}, {\"site\": 407, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": null, \"functional effect\": -2.8579, \"times_seen\": null}, {\"site\": 408, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 408, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": null, \"functional effect\": -0.7117, \"times_seen\": null}, {\"site\": 408, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": null, \"functional effect\": -2.8117, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -3.0028, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -2.8733, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -1.8136, \"times_seen\": null}, {\"site\": 409, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -2.8789, \"times_seen\": null}, {\"site\": 410, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": null, \"functional effect\": -2.9652, \"times_seen\": null}, {\"site\": 410, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 411, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": null, \"functional effect\": -1.4209, \"times_seen\": null}, {\"site\": 411, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 412, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -3.0001, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -2.8403, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -1.6747, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -2.3923, \"times_seen\": null}, {\"site\": 413, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -2.1237, \"times_seen\": null}, {\"site\": 414, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": null, \"functional effect\": -2.7518, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": -1.9397, \"times_seen\": null}, {\"site\": 415, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": -2.8834, \"times_seen\": null}, {\"site\": 416, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": null, \"functional effect\": -3.2606, \"times_seen\": null}, {\"site\": 416, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": null, \"functional effect\": -3.0208, \"times_seen\": null}, {\"site\": 416, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": null, \"functional effect\": -3.054, \"times_seen\": null}, {\"site\": 417, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": null, \"functional effect\": -1.248, \"times_seen\": null}, {\"site\": 418, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": null, \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 418, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": null, \"functional effect\": -3.0792, \"times_seen\": null}, {\"site\": 418, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": null, \"functional effect\": -0.7687, \"times_seen\": null}, {\"site\": 419, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": null, \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 419, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": null, \"functional effect\": -1.3291, \"times_seen\": null}, {\"site\": 419, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": null, \"functional effect\": -3.1359, \"times_seen\": null}, {\"site\": 420, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": null, \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 420, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": null, \"functional effect\": -2.8029, \"times_seen\": null}, {\"site\": 421, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": null, \"functional effect\": -1.7255, \"times_seen\": null}, {\"site\": 421, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": null, \"functional effect\": -1.4729, \"times_seen\": null}, {\"site\": 423, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": null, \"functional effect\": -2.878, \"times_seen\": null}, {\"site\": 423, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": null, \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 424, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": null, \"functional effect\": -0.5455, \"times_seen\": null}, {\"site\": 425, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": null, \"functional effect\": -2.5958, \"times_seen\": null}, {\"site\": 426, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": null, \"functional effect\": -2.3302, \"times_seen\": null}, {\"site\": 426, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": null, \"functional effect\": -2.9588, \"times_seen\": null}, {\"site\": 428, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": null, \"functional effect\": -3.1899, \"times_seen\": null}, {\"site\": 428, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": null, \"functional effect\": -2.9501, \"times_seen\": null}, {\"site\": 428, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -3.0255, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -0.53, \"times_seen\": null}, {\"site\": 429, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -2.5367, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -2.6833, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -3.0191, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -0.8518, \"times_seen\": null}, {\"site\": 430, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -2.9112, \"times_seen\": null}, {\"site\": 431, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": null, \"functional effect\": -0.9182, \"times_seen\": null}, {\"site\": 432, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": null, \"functional effect\": -3.0514, \"times_seen\": null}, {\"site\": 432, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 433, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": null, \"functional effect\": -3.1203, \"times_seen\": null}, {\"site\": 433, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": null, \"functional effect\": -3.0454, \"times_seen\": null}, {\"site\": 433, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": null, \"functional effect\": -2.542, \"times_seen\": null}, {\"site\": 434, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"437\", \"IC90\": null, \"functional effect\": -2.9261, \"times_seen\": null}, {\"site\": 435, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": null, \"functional effect\": -2.9463, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 437, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": null, \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 438, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": null, \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": null, \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": null, \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": null, \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": null, \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": null, \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": null, \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": null, \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": null, \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": null, \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": null, \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": null, \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 446, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": null, \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 447, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": null, \"functional effect\": 0.1636, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": -2.5122, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": -0.4405, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": -2.1395, \"times_seen\": null}, {\"site\": 450, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": null, \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -3.1241, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -3.2549, \"times_seen\": null}, {\"site\": 452, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": null, \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 452, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": null, \"functional effect\": -0.6037, \"times_seen\": null}, {\"site\": 453, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": null, \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 453, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": null, \"functional effect\": -3.2691, \"times_seen\": null}, {\"site\": 453, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": null, \"functional effect\": -2.5998, \"times_seen\": null}, {\"site\": 454, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": null, \"functional effect\": -3.0652, \"times_seen\": null}, {\"site\": 454, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": null, \"functional effect\": -2.1814, \"times_seen\": null}, {\"site\": 454, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": null, \"functional effect\": 0.0537, \"times_seen\": null}, {\"site\": 456, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": null, \"functional effect\": -0.2341, \"times_seen\": null}, {\"site\": 458, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": null, \"functional effect\": -2.9417, \"times_seen\": null}, {\"site\": 458, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": null, \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 458, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 459, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": null, \"functional effect\": -1.773, \"times_seen\": null}, {\"site\": 460, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": null, \"functional effect\": -3.2747, \"times_seen\": null}, {\"site\": 461, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": null, \"functional effect\": -3.2776, \"times_seen\": null}, {\"site\": 463, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": null, \"functional effect\": -3.1059, \"times_seen\": null}, {\"site\": 463, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": null, \"functional effect\": -3.0058, \"times_seen\": null}, {\"site\": 464, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": null, \"functional effect\": -2.9555, \"times_seen\": null}, {\"site\": 465, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": null, \"functional effect\": -1.9626, \"times_seen\": null}, {\"site\": 465, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": null, \"functional effect\": -0.5777, \"times_seen\": null}, {\"site\": 466, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": null, \"functional effect\": -2.7969, \"times_seen\": null}, {\"site\": 466, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": null, \"functional effect\": -1.23, \"times_seen\": null}, {\"site\": 469, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": null, \"functional effect\": -0.5576, \"times_seen\": null}, {\"site\": 471, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": null, \"functional effect\": -0.8613, \"times_seen\": null}, {\"site\": 473, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": null, \"functional effect\": -2.9062, \"times_seen\": null}, {\"site\": 474, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": null, \"functional effect\": 0.4453, \"times_seen\": null}, {\"site\": 476, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": null, \"functional effect\": -0.7712, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.9991, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.5488, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.9173, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 477, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.9774, \"times_seen\": null}, {\"site\": 478, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": null, \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 479, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": null, \"functional effect\": -3.0998, \"times_seen\": null}, {\"site\": 483, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": null, \"functional effect\": -0.1748, \"times_seen\": null}, {\"site\": 484, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": null, \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": -2.7516, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": -2.951, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": 0.2729, \"times_seen\": null}, {\"site\": 485, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": -2.9789, \"times_seen\": null}, {\"site\": 487, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": null, \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 487, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 488, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": null, \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 488, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": null, \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -3.2591, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -1.4113, \"times_seen\": null}, {\"site\": 489, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -2.4571, \"times_seen\": null}, {\"site\": 492, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 492, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": null, \"functional effect\": -2.3157, \"times_seen\": null}, {\"site\": 492, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": null, \"functional effect\": -2.2545, \"times_seen\": null}, {\"site\": 493, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": null, \"functional effect\": -3.0079, \"times_seen\": null}, {\"site\": 494, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": null, \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 494, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": null, \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 502, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": null, \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 503, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": null, \"functional effect\": -2.1871, \"times_seen\": null}, {\"site\": 503, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": null, \"functional effect\": -2.8228, \"times_seen\": null}, {\"site\": 504, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": null, \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 505, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 505, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": null, \"functional effect\": -2.3822, \"times_seen\": null}, {\"site\": 506, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 506, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": null, \"functional effect\": -3.2089, \"times_seen\": null}, {\"site\": 507, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 507, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": null, \"functional effect\": -2.4638, \"times_seen\": null}, {\"site\": 507, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": null, \"functional effect\": -2.8298, \"times_seen\": null}, {\"site\": 508, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 508, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": null, \"functional effect\": -3.0986, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.7182, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.9858, \"times_seen\": null}, {\"site\": 509, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.8415, \"times_seen\": null}, {\"site\": 510, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 510, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": null, \"functional effect\": -2.8948, \"times_seen\": null}, {\"site\": 511, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 511, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": null, \"functional effect\": -3.1416, \"times_seen\": null}, {\"site\": 511, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": null, \"functional effect\": -2.608, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -2.9644, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -3.2839, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -2.6904, \"times_seen\": null}, {\"site\": 512, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -2.3583, \"times_seen\": null}, {\"site\": 513, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": null, \"functional effect\": -0.8143, \"times_seen\": null}, {\"site\": 515, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": null, \"functional effect\": -0.5171, \"times_seen\": null}, {\"site\": 516, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": null, \"functional effect\": -1.0538, \"times_seen\": null}, {\"site\": 517, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": null, \"functional effect\": -2.0683, \"times_seen\": null}, {\"site\": 519, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": null, \"functional effect\": -0.36, \"times_seen\": null}, {\"site\": 520, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": null, \"functional effect\": -2.1929, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -3.2398, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -0.1108, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -2.3718, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -0.9578, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -2.8275, \"times_seen\": null}, {\"site\": 521, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -3.0875, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -2.9129, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -2.9482, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -1.8801, \"times_seen\": null}, {\"site\": 522, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -3.1198, \"times_seen\": null}, {\"site\": 523, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": null, \"functional effect\": -2.4069, \"times_seen\": null}, {\"site\": 524, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": null, \"functional effect\": -2.6649, \"times_seen\": null}, {\"site\": 524, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": null, \"functional effect\": -2.5665, \"times_seen\": null}, {\"site\": 525, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 525, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": null, \"functional effect\": -0.7343, \"times_seen\": null}, {\"site\": 525, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": null, \"functional effect\": -2.9407, \"times_seen\": null}, {\"site\": 527, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": null, \"functional effect\": -3.261, \"times_seen\": null}, {\"site\": 527, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": null, \"functional effect\": -2.6451, \"times_seen\": null}, {\"site\": 527, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -2.6907, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -3.0131, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -1.7137, \"times_seen\": null}, {\"site\": 528, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -1.218, \"times_seen\": null}, {\"site\": 529, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": null, \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -2.1012, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -3.1267, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -3.2559, \"times_seen\": null}, {\"site\": 530, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -2.5095, \"times_seen\": null}, {\"site\": 531, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": null, \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 531, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": null, \"functional effect\": -1.9197, \"times_seen\": null}, {\"site\": 531, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": null, \"functional effect\": -2.5316, \"times_seen\": null}, {\"site\": 532, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": null, \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 532, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": null, \"functional effect\": -1.7736, \"times_seen\": null}, {\"site\": 532, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": null, \"functional effect\": -2.633, \"times_seen\": null}, {\"site\": 533, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": null, \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 533, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": null, \"functional effect\": -3.0933, \"times_seen\": null}, {\"site\": 534, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": null, \"functional effect\": -2.101, \"times_seen\": null}, {\"site\": 534, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": null, \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -2.9372, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -3.0562, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -2.9066, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -3.233, \"times_seen\": null}, {\"site\": 535, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -2.4097, \"times_seen\": null}, {\"site\": 536, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": null, \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 536, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": null, \"functional effect\": -2.809, \"times_seen\": null}, {\"site\": 537, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": null, \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -2.7164, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -3.0898, \"times_seen\": null}, {\"site\": 538, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -2.6257, \"times_seen\": null}, {\"site\": 539, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": null, \"functional effect\": -2.4756, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -0.0019, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -2.6852, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 540, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -2.884, \"times_seen\": null}, {\"site\": 541, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 541, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": null, \"functional effect\": -0.4128, \"times_seen\": null}, {\"site\": 542, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": null, \"functional effect\": -2.9755, \"times_seen\": null}, {\"site\": 542, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": null, \"functional effect\": -2.7771, \"times_seen\": null}, {\"site\": 543, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": null, \"functional effect\": -2.9377, \"times_seen\": null}, {\"site\": 544, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": null, \"functional effect\": -2.6726, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -2.9917, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -2.9874, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -3.0095, \"times_seen\": null}, {\"site\": 545, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -2.7874, \"times_seen\": null}, {\"site\": 546, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": null, \"functional effect\": -1.0964, \"times_seen\": null}, {\"site\": 547, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": null, \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 547, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": null, \"functional effect\": -2.9819, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -2.9188, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -3.0603, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -2.8877, \"times_seen\": null}, {\"site\": 548, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -0.1976, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -2.9185, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -1.9556, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -3.2497, \"times_seen\": null}, {\"site\": 549, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -3.0461, \"times_seen\": null}, {\"site\": 550, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": null, \"functional effect\": -2.0618, \"times_seen\": null}, {\"site\": 551, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": null, \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 551, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": null, \"functional effect\": -2.7917, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -3.0124, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -3.1316, \"times_seen\": null}, {\"site\": 552, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -1.6653, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -2.2885, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -2.9281, \"times_seen\": null}, {\"site\": 554, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -2.5397, \"times_seen\": null}, {\"site\": 555, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": null, \"functional effect\": -2.0148, \"times_seen\": null}, {\"site\": 555, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": null, \"functional effect\": -0.385, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -1.1, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -1.2662, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -2.924, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -0.4951, \"times_seen\": null}, {\"site\": 556, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -2.585, \"times_seen\": null}, {\"site\": 559, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": null, \"functional effect\": -3.1555, \"times_seen\": null}, {\"site\": 559, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": null, \"functional effect\": -3.0884, \"times_seen\": null}, {\"site\": 560, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": null, \"functional effect\": -2.4618, \"times_seen\": null}, {\"site\": 561, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": null, \"functional effect\": -0.38, \"times_seen\": null}, {\"site\": 561, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 562, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": null, \"functional effect\": -2.3316, \"times_seen\": null}, {\"site\": 563, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": null, \"functional effect\": -2.9434, \"times_seen\": null}, {\"site\": 563, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": null, \"functional effect\": -0.5665, \"times_seen\": null}, {\"site\": 563, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": null, \"functional effect\": -2.3366, \"times_seen\": null}, {\"site\": 564, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": null, \"functional effect\": -0.4161, \"times_seen\": null}, {\"site\": 565, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 565, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": null, \"functional effect\": -1.5973, \"times_seen\": null}, {\"site\": 565, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": null, \"functional effect\": -3.0982, \"times_seen\": null}, {\"site\": 566, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": null, \"functional effect\": -1.5911, \"times_seen\": null}, {\"site\": 568, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": null, \"functional effect\": -2.0259, \"times_seen\": null}, {\"site\": 570, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": null, \"functional effect\": -1.5474, \"times_seen\": null}, {\"site\": 570, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": null, \"functional effect\": -1.3033, \"times_seen\": null}, {\"site\": 570, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": null, \"functional effect\": -1.4348, \"times_seen\": null}, {\"site\": 572, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": null, \"functional effect\": -3.0047, \"times_seen\": null}, {\"site\": 572, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": null, \"functional effect\": 0.7078, \"times_seen\": null}, {\"site\": 574, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": null, \"functional effect\": -2.8795, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -3.0225, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -3.085, \"times_seen\": null}, {\"site\": 575, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -2.8685, \"times_seen\": null}, {\"site\": 576, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": null, \"functional effect\": -1.6729, \"times_seen\": null}, {\"site\": 576, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": null, \"functional effect\": -2.1658, \"times_seen\": null}, {\"site\": 576, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": null, \"functional effect\": -2.6607, \"times_seen\": null}, {\"site\": 577, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": null, \"functional effect\": -2.4574, \"times_seen\": null}, {\"site\": 578, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": null, \"functional effect\": 0.0867, \"times_seen\": null}, {\"site\": 578, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": null, \"functional effect\": -0.8684, \"times_seen\": null}, {\"site\": 580, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": null, \"functional effect\": -1.4807, \"times_seen\": null}, {\"site\": 580, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": null, \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 581, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": null, \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 581, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": null, \"functional effect\": -3.0759, \"times_seen\": null}, {\"site\": 581, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": null, \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 582, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": null, \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 582, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": null, \"functional effect\": -3.0671, \"times_seen\": null}, {\"site\": 582, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": null, \"functional effect\": -1.8692, \"times_seen\": null}, {\"site\": 583, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": null, \"functional effect\": -1.6565, \"times_seen\": null}, {\"site\": 583, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": null, \"functional effect\": -3.0571, \"times_seen\": null}, {\"site\": 583, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": null, \"functional effect\": -1.7541, \"times_seen\": null}, {\"site\": 584, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": null, \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 586, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": null, \"functional effect\": -2.6176, \"times_seen\": null}, {\"site\": 586, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": null, \"functional effect\": -2.9764, \"times_seen\": null}, {\"site\": 586, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": null, \"functional effect\": -2.5191, \"times_seen\": null}, {\"site\": 587, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": null, \"functional effect\": -2.9546, \"times_seen\": null}, {\"site\": 587, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": null, \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 589, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 589, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": null, \"functional effect\": -2.9925, \"times_seen\": null}, {\"site\": 590, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": null, \"functional effect\": -3.1088, \"times_seen\": null}, {\"site\": 590, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": null, \"functional effect\": -1.8569, \"times_seen\": null}, {\"site\": 593, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": null, \"functional effect\": -2.9489, \"times_seen\": null}, {\"site\": 594, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 594, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": null, \"functional effect\": -3.0615, \"times_seen\": null}, {\"site\": 594, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": null, \"functional effect\": -2.8088, \"times_seen\": null}, {\"site\": 595, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 595, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": null, \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 595, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": null, \"functional effect\": -3.2609, \"times_seen\": null}, {\"site\": 596, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 596, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": null, \"functional effect\": -2.6075, \"times_seen\": null}, {\"site\": 596, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": null, \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 597, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 597, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": null, \"functional effect\": -3.0462, \"times_seen\": null}, {\"site\": 597, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": null, \"functional effect\": -2.9775, \"times_seen\": null}, {\"site\": 598, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": null, \"functional effect\": -3.237, \"times_seen\": null}, {\"site\": 598, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": null, \"functional effect\": -2.1284, \"times_seen\": null}, {\"site\": 599, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": null, \"functional effect\": -2.3607, \"times_seen\": null}, {\"site\": 599, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": null, \"functional effect\": -1.7296, \"times_seen\": null}, {\"site\": 599, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": null, \"functional effect\": -3.0817, \"times_seen\": null}, {\"site\": 600, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": null, \"functional effect\": -0.8372, \"times_seen\": null}, {\"site\": 602, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": null, \"functional effect\": -3.1345, \"times_seen\": null}, {\"site\": 602, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": null, \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 602, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 603, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 603, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": null, \"functional effect\": -0.133, \"times_seen\": null}, {\"site\": 604, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": null, \"functional effect\": -0.3317, \"times_seen\": null}, {\"site\": 605, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": null, \"functional effect\": -1.4881, \"times_seen\": null}, {\"site\": 605, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": null, \"functional effect\": -2.9968, \"times_seen\": null}, {\"site\": 606, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": null, \"functional effect\": -2.843, \"times_seen\": null}, {\"site\": 606, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": null, \"functional effect\": -2.0465, \"times_seen\": null}, {\"site\": 607, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": null, \"functional effect\": -3.0487, \"times_seen\": null}, {\"site\": 607, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": null, \"functional effect\": -3.2443, \"times_seen\": null}, {\"site\": 607, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": null, \"functional effect\": -2.9958, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.9547, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.7929, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.9456, \"times_seen\": null}, {\"site\": 609, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.9307, \"times_seen\": null}, {\"site\": 611, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": null, \"functional effect\": -2.8327, \"times_seen\": null}, {\"site\": 612, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": null, \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -2.8497, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -2.5949, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -1.2614, \"times_seen\": null}, {\"site\": 614, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -3.132, \"times_seen\": null}, {\"site\": 616, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": null, \"functional effect\": -1.4132, \"times_seen\": null}, {\"site\": 617, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": null, \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 617, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": null, \"functional effect\": -2.1861, \"times_seen\": null}, {\"site\": 618, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": null, \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 618, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": null, \"functional effect\": -0.3843, \"times_seen\": null}, {\"site\": 619, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": null, \"functional effect\": -2.2694, \"times_seen\": null}, {\"site\": 620, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": null, \"functional effect\": -1.736, \"times_seen\": null}, {\"site\": 620, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": null, \"functional effect\": -1.2151, \"times_seen\": null}, {\"site\": 621, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": null, \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 621, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": null, \"functional effect\": -2.6612, \"times_seen\": null}, {\"site\": 622, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": null, \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 623, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 624, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": null, \"functional effect\": -1.7134, \"times_seen\": null}, {\"site\": 625, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": null, \"functional effect\": -1.9116, \"times_seen\": null}, {\"site\": 625, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": null, \"functional effect\": -2.8236, \"times_seen\": null}, {\"site\": 626, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": null, \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 627, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": null, \"functional effect\": -2.6515, \"times_seen\": null}, {\"site\": 627, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": null, \"functional effect\": -0.6732, \"times_seen\": null}, {\"site\": 628, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": null, \"functional effect\": -2.5612, \"times_seen\": null}, {\"site\": 629, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": null, \"functional effect\": -0.5555, \"times_seen\": null}, {\"site\": 630, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": null, \"functional effect\": -3.2461, \"times_seen\": null}, {\"site\": 630, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 631, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": null, \"functional effect\": -0.6942, \"times_seen\": null}, {\"site\": 632, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": null, \"functional effect\": -0.0971, \"times_seen\": null}, {\"site\": 633, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": null, \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 633, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": null, \"functional effect\": -3.0175, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": -2.2629, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": -3.2586, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": -1.5063, \"times_seen\": null}, {\"site\": 634, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": 0.5058, \"times_seen\": null}, {\"site\": 637, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 638, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": null, \"functional effect\": -0.6966, \"times_seen\": null}, {\"site\": 639, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": null, \"functional effect\": 0.2404, \"times_seen\": null}, {\"site\": 640, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": null, \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 641, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": null, \"functional effect\": -1.2621, \"times_seen\": null}, {\"site\": 641, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 641, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": null, \"functional effect\": -2.1822, \"times_seen\": null}, {\"site\": 642, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": null, \"functional effect\": -2.5747, \"times_seen\": null}, {\"site\": 642, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": null, \"functional effect\": -0.1741, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -3.2615, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -3.1376, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -2.739, \"times_seen\": null}, {\"site\": 645, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -2.6423, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -3.1327, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.2135, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.922, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.479, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.7214, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 646, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.8815, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.8995, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.5692, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -1.9246, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.9784, \"times_seen\": null}, {\"site\": 647, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.8907, \"times_seen\": null}, {\"site\": 648, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": null, \"functional effect\": -1.796, \"times_seen\": null}, {\"site\": 648, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": null, \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 648, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": null, \"functional effect\": -2.9986, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.9974, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.918, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.6322, \"times_seen\": null}, {\"site\": 649, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.8331, \"times_seen\": null}, {\"site\": 650, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 650, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": null, \"functional effect\": -2.8205, \"times_seen\": null}, {\"site\": 650, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": null, \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 651, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 651, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": null, \"functional effect\": 0.1923, \"times_seen\": null}, {\"site\": 652, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 653, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 654, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 654, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": null, \"functional effect\": -0.8364, \"times_seen\": null}, {\"site\": 655, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 655, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": null, \"functional effect\": -0.4271, \"times_seen\": null}, {\"site\": 656, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 657, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": null, \"functional effect\": -1.5896, \"times_seen\": null}, {\"site\": 657, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 657, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": null, \"functional effect\": -0.4082, \"times_seen\": null}, {\"site\": 658, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": null, \"functional effect\": -3.087, \"times_seen\": null}, {\"site\": 658, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 659, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": null, \"functional effect\": -3.1855, \"times_seen\": null}, {\"site\": 659, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 660, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 660, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": null, \"functional effect\": -1.7556, \"times_seen\": null}, {\"site\": 660, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": null, \"functional effect\": -3.125, \"times_seen\": null}, {\"site\": 661, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 661, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": null, \"functional effect\": -2.3552, \"times_seen\": null}, {\"site\": 661, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": null, \"functional effect\": -2.2529, \"times_seen\": null}, {\"site\": 662, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 662, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": null, \"functional effect\": -2.1018, \"times_seen\": null}, {\"site\": 662, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": null, \"functional effect\": -1.5219, \"times_seen\": null}, {\"site\": 663, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": null, \"functional effect\": -2.7785, \"times_seen\": null}, {\"site\": 664, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": null, \"functional effect\": -1.7201, \"times_seen\": null}, {\"site\": 666, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": null, \"functional effect\": -0.7519, \"times_seen\": null}, {\"site\": 666, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": null, \"functional effect\": -3.2764, \"times_seen\": null}, {\"site\": 668, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": null, \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 668, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": null, \"functional effect\": -2.9839, \"times_seen\": null}, {\"site\": 669, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": null, \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 669, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": null, \"functional effect\": -2.7085, \"times_seen\": null}, {\"site\": 670, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": null, \"functional effect\": -2.1489, \"times_seen\": null}, {\"site\": 671, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": null, \"functional effect\": -2.2944, \"times_seen\": null}, {\"site\": 671, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": null, \"functional effect\": -3.0437, \"times_seen\": null}, {\"site\": 672, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": null, \"functional effect\": -1.5438, \"times_seen\": null}, {\"site\": 672, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": null, \"functional effect\": -0.3102, \"times_seen\": null}, {\"site\": 672, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": null, \"functional effect\": -3.2213, \"times_seen\": null}, {\"site\": 674, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": null, \"functional effect\": -0.2997, \"times_seen\": null}, {\"site\": 679, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": null, \"functional effect\": 0.7621, \"times_seen\": null}, {\"site\": 680, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": null, \"functional effect\": 0.0362, \"times_seen\": null}, {\"site\": 680, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": null, \"functional effect\": 0.019, \"times_seen\": null}, {\"site\": 681, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": null, \"functional effect\": -0.2085, \"times_seen\": null}, {\"site\": 682, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": null, \"functional effect\": -0.0979, \"times_seen\": null}, {\"site\": 684, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": null, \"functional effect\": 0.9512, \"times_seen\": null}, {\"site\": 685, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": null, \"functional effect\": -2.9234, \"times_seen\": null}, {\"site\": 686, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": null, \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 686, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": null, \"functional effect\": -0.173, \"times_seen\": null}, {\"site\": 687, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": null, \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 689, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": null, \"functional effect\": -3.2584, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -1.3379, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -1.3074, \"times_seen\": null}, {\"site\": 690, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -3.066, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -3.0186, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -3.2784, \"times_seen\": null}, {\"site\": 691, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 693, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": null, \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 693, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": null, \"functional effect\": -0.3019, \"times_seen\": null}, {\"site\": 694, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": null, \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 694, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": null, \"functional effect\": -2.6723, \"times_seen\": null}, {\"site\": 695, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": null, \"functional effect\": -1.3615, \"times_seen\": null}, {\"site\": 696, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": null, \"functional effect\": -3.0141, \"times_seen\": null}, {\"site\": 696, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": null, \"functional effect\": -0.7797, \"times_seen\": null}, {\"site\": 697, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": null, \"functional effect\": -2.3439, \"times_seen\": null}, {\"site\": 697, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": null, \"functional effect\": -3.0251, \"times_seen\": null}, {\"site\": 699, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": null, \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 701, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": null, \"functional effect\": -0.8183, \"times_seen\": null}, {\"site\": 702, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": null, \"functional effect\": -2.9829, \"times_seen\": null}, {\"site\": 703, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": null, \"functional effect\": -2.0658, \"times_seen\": null}, {\"site\": 703, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": null, \"functional effect\": -2.8496, \"times_seen\": null}, {\"site\": 704, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": null, \"functional effect\": -2.2896, \"times_seen\": null}, {\"site\": 705, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": null, \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 705, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": null, \"functional effect\": -2.4402, \"times_seen\": null}, {\"site\": 705, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": null, \"functional effect\": -2.8747, \"times_seen\": null}, {\"site\": 706, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": null, \"functional effect\": -2.9375, \"times_seen\": null}, {\"site\": 707, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 708, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": null, \"functional effect\": -0.8443, \"times_seen\": null}, {\"site\": 708, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": null, \"functional effect\": -2.9811, \"times_seen\": null}, {\"site\": 709, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": null, \"functional effect\": -3.249, \"times_seen\": null}, {\"site\": 711, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": null, \"functional effect\": -3.2101, \"times_seen\": null}, {\"site\": 711, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": null, \"functional effect\": -2.9601, \"times_seen\": null}, {\"site\": 712, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 713, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": null, \"functional effect\": -2.874, \"times_seen\": null}, {\"site\": 714, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": null, \"functional effect\": -1.1916, \"times_seen\": null}, {\"site\": 714, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": null, \"functional effect\": -3.1123, \"times_seen\": null}, {\"site\": 714, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": null, \"functional effect\": -2.0513, \"times_seen\": null}, {\"site\": 715, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": null, \"functional effect\": -2.8163, \"times_seen\": null}, {\"site\": 715, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": null, \"functional effect\": -3.1152, \"times_seen\": null}, {\"site\": 715, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": null, \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 716, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": null, \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 717, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": null, \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 717, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": null, \"functional effect\": -2.6514, \"times_seen\": null}, {\"site\": 717, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": null, \"functional effect\": -3.0739, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -0.482, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -1.6494, \"times_seen\": null}, {\"site\": 718, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -0.2213, \"times_seen\": null}, {\"site\": 719, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": null, \"functional effect\": -1.8183, \"times_seen\": null}, {\"site\": 719, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": null, \"functional effect\": -2.9973, \"times_seen\": null}, {\"site\": 719, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": null, \"functional effect\": -2.8552, \"times_seen\": null}, {\"site\": 720, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": null, \"functional effect\": -0.2352, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -2.9082, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -3.0518, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -3.1332, \"times_seen\": null}, {\"site\": 722, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -2.8455, \"times_seen\": null}, {\"site\": 723, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": null, \"functional effect\": -2.682, \"times_seen\": null}, {\"site\": 724, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": null, \"functional effect\": -2.2196, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -2.4798, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -2.37, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -1.6758, \"times_seen\": null}, {\"site\": 725, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -0.7129, \"times_seen\": null}, {\"site\": 726, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 726, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": null, \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 726, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": null, \"functional effect\": -2.8622, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": 0.4189, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -2.1244, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -1.0604, \"times_seen\": null}, {\"site\": 727, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -2.4419, \"times_seen\": null}, {\"site\": 728, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": null, \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 728, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": null, \"functional effect\": -2.606, \"times_seen\": null}, {\"site\": 728, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 729, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 729, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 729, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": null, \"functional effect\": -2.9597, \"times_seen\": null}, {\"site\": 730, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 730, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": null, \"functional effect\": -3.1325, \"times_seen\": null}, {\"site\": 730, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": null, \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 731, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 731, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": null, \"functional effect\": -2.9745, \"times_seen\": null}, {\"site\": 732, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 732, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": null, \"functional effect\": -2.7322, \"times_seen\": null}, {\"site\": 732, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": null, \"functional effect\": 0.6738, \"times_seen\": null}, {\"site\": 733, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": null, \"functional effect\": -1.6969, \"times_seen\": null}, {\"site\": 733, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": null, \"functional effect\": -2.9548, \"times_seen\": null}, {\"site\": 735, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": null, \"functional effect\": -2.9813, \"times_seen\": null}, {\"site\": 735, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": null, \"functional effect\": -2.9196, \"times_seen\": null}, {\"site\": 735, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 737, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": -2.5015, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 738, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": -1.5617, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -3.0936, \"times_seen\": null}, {\"site\": 739, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -0.6647, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -3.0343, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -2.8525, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -3.0053, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -3.052, \"times_seen\": null}, {\"site\": 740, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -2.6502, \"times_seen\": null}, {\"site\": 741, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": null, \"functional effect\": -2.6347, \"times_seen\": null}, {\"site\": 741, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 741, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": null, \"functional effect\": 0.4254, \"times_seen\": null}, {\"site\": 742, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 742, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": null, \"functional effect\": -1.1698, \"times_seen\": null}, {\"site\": 743, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 744, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -2.9623, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -0.4818, \"times_seen\": null}, {\"site\": 745, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -0.1913, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -3.0745, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -2.9607, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -3.0024, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -2.8875, \"times_seen\": null}, {\"site\": 746, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 747, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 748, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 749, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 749, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": null, \"functional effect\": -0.0322, \"times_seen\": null}, {\"site\": 750, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 750, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": null, \"functional effect\": -2.9731, \"times_seen\": null}, {\"site\": 751, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -0.6948, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -0.9599, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -3.234, \"times_seen\": null}, {\"site\": 752, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": 0.4155, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -3.0014, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -1.2583, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -1.0683, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -0.7486, \"times_seen\": null}, {\"site\": 753, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -3.1031, \"times_seen\": null}, {\"site\": 754, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": null, \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.4519, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.919, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -3.0579, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.6628, \"times_seen\": null}, {\"site\": 757, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.8402, \"times_seen\": null}, {\"site\": 759, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": null, \"functional effect\": -1.8736, \"times_seen\": null}, {\"site\": 759, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": null, \"functional effect\": -0.5475, \"times_seen\": null}, {\"site\": 762, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": null, \"functional effect\": -2.6327, \"times_seen\": null}, {\"site\": 762, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": null, \"functional effect\": -1.1381, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -3.2893, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -2.8309, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 764, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -3.2678, \"times_seen\": null}, {\"site\": 765, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": null, \"functional effect\": -0.6456, \"times_seen\": null}, {\"site\": 766, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": null, \"functional effect\": -2.8225, \"times_seen\": null}, {\"site\": 768, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": null, \"functional effect\": -2.9716, \"times_seen\": null}, {\"site\": 768, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": null, \"functional effect\": -2.493, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": -2.9508, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": -1.329, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": 0.5283, \"times_seen\": null}, {\"site\": 770, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": -3.2891, \"times_seen\": null}, {\"site\": 771, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": null, \"functional effect\": -1.5265, \"times_seen\": null}, {\"site\": 771, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": null, \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 771, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": null, \"functional effect\": -2.9984, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.2599, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.568, \"times_seen\": null}, {\"site\": 772, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.4226, \"times_seen\": null}, {\"site\": 773, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 776, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": null, \"functional effect\": -3.2663, \"times_seen\": null}, {\"site\": 777, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": null, \"functional effect\": 0.576, \"times_seen\": null}, {\"site\": 777, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": null, \"functional effect\": -1.6764, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -1.0729, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -2.8674, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -2.9742, \"times_seen\": null}, {\"site\": 778, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -1.6866, \"times_seen\": null}, {\"site\": 779, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": null, \"functional effect\": -2.6266, \"times_seen\": null}, {\"site\": 779, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": null, \"functional effect\": -2.92, \"times_seen\": null}, {\"site\": 782, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": null, \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 782, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": null, \"functional effect\": -0.3291, \"times_seen\": null}, {\"site\": 783, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": null, \"functional effect\": -0.2916, \"times_seen\": null}, {\"site\": 787, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": null, \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 787, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": null, \"functional effect\": -2.6097, \"times_seen\": null}, {\"site\": 788, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": null, \"functional effect\": -0.6799, \"times_seen\": null}, {\"site\": 788, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": null, \"functional effect\": -0.0459, \"times_seen\": null}, {\"site\": 789, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": null, \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 789, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": null, \"functional effect\": 0.6623, \"times_seen\": null}, {\"site\": 789, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": null, \"functional effect\": -0.9385, \"times_seen\": null}, {\"site\": 790, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": null, \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 791, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 791, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 793, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": null, \"functional effect\": -2.8316, \"times_seen\": null}, {\"site\": 795, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": null, \"functional effect\": -2.8864, \"times_seen\": null}, {\"site\": 796, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 798, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": null, \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 798, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": null, \"functional effect\": -3.0358, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -2.0436, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -3.1372, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -1.5288, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 799, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -0.9458, \"times_seen\": null}, {\"site\": 800, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": null, \"functional effect\": -2.8923, \"times_seen\": null}, {\"site\": 801, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": null, \"functional effect\": -1.5857, \"times_seen\": null}, {\"site\": 801, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": null, \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 802, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": null, \"functional effect\": -3.1385, \"times_seen\": null}, {\"site\": 802, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": null, \"functional effect\": -3.15, \"times_seen\": null}, {\"site\": 802, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": null, \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 803, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": null, \"functional effect\": -2.1869, \"times_seen\": null}, {\"site\": 803, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": null, \"functional effect\": -2.8206, \"times_seen\": null}, {\"site\": 803, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": null, \"functional effect\": -2.3767, \"times_seen\": null}, {\"site\": 804, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 804, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": null, \"functional effect\": -1.7397, \"times_seen\": null}, {\"site\": 806, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": null, \"functional effect\": -1.2617, \"times_seen\": null}, {\"site\": 808, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": null, \"functional effect\": -3.1474, \"times_seen\": null}, {\"site\": 811, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 812, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": null, \"functional effect\": -3.0625, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.4196, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.9671, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.4335, \"times_seen\": null}, {\"site\": 813, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.9258, \"times_seen\": null}, {\"site\": 814, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": null, \"functional effect\": -2.0337, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -1.803, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -1.02, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -0.2899, \"times_seen\": null}, {\"site\": 815, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -2.8965, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -3.1856, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -2.2359, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -2.6892, \"times_seen\": null}, {\"site\": 816, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -2.9667, \"times_seen\": null}, {\"site\": 817, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 817, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": null, \"functional effect\": -2.0701, \"times_seen\": null}, {\"site\": 817, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": null, \"functional effect\": -2.7805, \"times_seen\": null}, {\"site\": 818, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.0771, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.2833, \"times_seen\": null}, {\"site\": 819, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.8673, \"times_seen\": null}, {\"site\": 820, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 820, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": null, \"functional effect\": -3.146, \"times_seen\": null}, {\"site\": 820, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": null, \"functional effect\": -3.0631, \"times_seen\": null}, {\"site\": 821, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 821, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": null, \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -3.0041, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 822, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -0.9509, \"times_seen\": null}, {\"site\": 823, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 823, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": null, \"functional effect\": -1.6687, \"times_seen\": null}, {\"site\": 824, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 824, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": null, \"functional effect\": -1.2831, \"times_seen\": null}, {\"site\": 825, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 825, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": null, \"functional effect\": -1.3233, \"times_seen\": null}, {\"site\": 826, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 827, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 828, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": null, \"functional effect\": -1.3054, \"times_seen\": null}, {\"site\": 828, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 828, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": null, \"functional effect\": -0.1246, \"times_seen\": null}, {\"site\": 829, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 829, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": null, \"functional effect\": -2.6684, \"times_seen\": null}, {\"site\": 829, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": null, \"functional effect\": -1.0359, \"times_seen\": null}, {\"site\": 830, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 831, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 831, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": null, \"functional effect\": -0.9074, \"times_seen\": null}, {\"site\": 832, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": null, \"functional effect\": -2.0011, \"times_seen\": null}, {\"site\": 832, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 832, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": null, \"functional effect\": -1.8672, \"times_seen\": null}, {\"site\": 833, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": null, \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 834, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": null, \"functional effect\": -2.8644, \"times_seen\": null}, {\"site\": 834, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": null, \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 835, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": null, \"functional effect\": -2.4752, \"times_seen\": null}, {\"site\": 835, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 836, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 836, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": null, \"functional effect\": -0.6005, \"times_seen\": null}, {\"site\": 837, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 837, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": null, \"functional effect\": -1.6807, \"times_seen\": null}, {\"site\": 838, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 839, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": null, \"functional effect\": -3.0653, \"times_seen\": null}, {\"site\": 839, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": null, \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 839, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": null, \"functional effect\": 0.7771, \"times_seen\": null}, {\"site\": 840, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": null, \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 840, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": null, \"functional effect\": -3.2587, \"times_seen\": null}, {\"site\": 840, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": null, \"functional effect\": -3.0689, \"times_seen\": null}, {\"site\": 843, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": null, \"functional effect\": -2.7207, \"times_seen\": null}, {\"site\": 844, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": null, \"functional effect\": -1.9387, \"times_seen\": null}, {\"site\": 846, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": null, \"functional effect\": -2.5052, \"times_seen\": null}, {\"site\": 846, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": null, \"functional effect\": -3.1951, \"times_seen\": null}, {\"site\": 847, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": null, \"functional effect\": -3.2539, \"times_seen\": null}, {\"site\": 847, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": null, \"functional effect\": -2.5485, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.9615, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.5732, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.4251, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.5641, \"times_seen\": null}, {\"site\": 848, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 849, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": null, \"functional effect\": -1.3309, \"times_seen\": null}, {\"site\": 850, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": null, \"functional effect\": -2.661, \"times_seen\": null}, {\"site\": 850, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": null, \"functional effect\": -1.5723, \"times_seen\": null}, {\"site\": 851, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 852, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": null, \"functional effect\": -1.965, \"times_seen\": null}, {\"site\": 852, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": null, \"functional effect\": -2.4708, \"times_seen\": null}, {\"site\": 854, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": null, \"functional effect\": -3.0382, \"times_seen\": null}, {\"site\": 854, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": null, \"functional effect\": -3.0362, \"times_seen\": null}, {\"site\": 857, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": null, \"functional effect\": -2.9421, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": -2.1524, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": -3.2746, \"times_seen\": null}, {\"site\": 858, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": -1.6898, \"times_seen\": null}, {\"site\": 861, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": null, \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 861, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": null, \"functional effect\": -2.7403, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -2.9684, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -1.8793, \"times_seen\": null}, {\"site\": 862, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -2.3348, \"times_seen\": null}, {\"site\": 863, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": null, \"functional effect\": -2.0678, \"times_seen\": null}, {\"site\": 864, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": null, \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 864, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 864, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": null, \"functional effect\": -2.9937, \"times_seen\": null}, {\"site\": 865, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": null, \"functional effect\": -2.9627, \"times_seen\": null}, {\"site\": 865, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": null, \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 866, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": null, \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 866, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": null, \"functional effect\": -1.1256, \"times_seen\": null}, {\"site\": 866, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": null, \"functional effect\": -1.6846, \"times_seen\": null}, {\"site\": 867, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 867, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": null, \"functional effect\": -3.029, \"times_seen\": null}, {\"site\": 867, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": null, \"functional effect\": -1.3361, \"times_seen\": null}, {\"site\": 868, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": null, \"functional effect\": -2.4325, \"times_seen\": null}, {\"site\": 868, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": null, \"functional effect\": -1.963, \"times_seen\": null}, {\"site\": 868, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": null, \"functional effect\": -1.1637, \"times_seen\": null}, {\"site\": 870, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": null, \"functional effect\": -3.2859, \"times_seen\": null}, {\"site\": 870, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": null, \"functional effect\": -2.3176, \"times_seen\": null}, {\"site\": 870, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": null, \"functional effect\": -3.0674, \"times_seen\": null}, {\"site\": 871, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": null, \"functional effect\": -0.2002, \"times_seen\": null}, {\"site\": 873, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": null, \"functional effect\": -2.9101, \"times_seen\": null}, {\"site\": 873, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": null, \"functional effect\": -2.995, \"times_seen\": null}, {\"site\": 874, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": null, \"functional effect\": -2.9952, \"times_seen\": null}, {\"site\": 874, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": null, \"functional effect\": -1.8158, \"times_seen\": null}, {\"site\": 874, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": null, \"functional effect\": -1.083, \"times_seen\": null}, {\"site\": 875, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": null, \"functional effect\": -2.1864, \"times_seen\": null}, {\"site\": 875, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": null, \"functional effect\": -1.5423, \"times_seen\": null}, {\"site\": 875, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": null, \"functional effect\": -3.0457, \"times_seen\": null}, {\"site\": 876, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": null, \"functional effect\": -3.1006, \"times_seen\": null}, {\"site\": 877, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": null, \"functional effect\": -1.703, \"times_seen\": null}, {\"site\": 877, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": null, \"functional effect\": -3.1228, \"times_seen\": null}, {\"site\": 878, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 879, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": null, \"functional effect\": -2.8883, \"times_seen\": null}, {\"site\": 879, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": null, \"functional effect\": -3.1585, \"times_seen\": null}, {\"site\": 879, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": null, \"functional effect\": -3.3372, \"times_seen\": null}, {\"site\": 882, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": null, \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 882, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": null, \"functional effect\": -2.766, \"times_seen\": null}, {\"site\": 883, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": null, \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 883, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": null, \"functional effect\": -0.9736, \"times_seen\": null}, {\"site\": 884, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": null, \"functional effect\": -2.0907, \"times_seen\": null}, {\"site\": 885, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": null, \"functional effect\": -2.771, \"times_seen\": null}, {\"site\": 885, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": null, \"functional effect\": -3.2601, \"times_seen\": null}, {\"site\": 885, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": null, \"functional effect\": -1.3239, \"times_seen\": null}, {\"site\": 887, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": null, \"functional effect\": -3.0009, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -2.7005, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -2.6779, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -2.8072, \"times_seen\": null}, {\"site\": 888, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -1.7267, \"times_seen\": null}, {\"site\": 890, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": null, \"functional effect\": -3.0043, \"times_seen\": null}, {\"site\": 890, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": null, \"functional effect\": -0.3442, \"times_seen\": null}, {\"site\": 891, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": null, \"functional effect\": -2.0987, \"times_seen\": null}, {\"site\": 892, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": null, \"functional effect\": -2.98, \"times_seen\": null}, {\"site\": 893, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": null, \"functional effect\": -2.1962, \"times_seen\": null}, {\"site\": 893, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": null, \"functional effect\": -3.0026, \"times_seen\": null}, {\"site\": 894, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": null, \"functional effect\": -3.1269, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -2.8593, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -2.4705, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -3.2656, \"times_seen\": null}, {\"site\": 895, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -1.7283, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -0.2541, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -3.114, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -1.9072, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -2.5266, \"times_seen\": null}, {\"site\": 897, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -2.9127, \"times_seen\": null}, {\"site\": 898, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": null, \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 898, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 899, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": null, \"functional effect\": -3.0013, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -2.9945, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -2.4536, \"times_seen\": null}, {\"site\": 900, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -0.2027, \"times_seen\": null}, {\"site\": 901, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": null, \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 901, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": null, \"functional effect\": -2.0755, \"times_seen\": null}, {\"site\": 902, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": null, \"functional effect\": -2.8707, \"times_seen\": null}, {\"site\": 902, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": null, \"functional effect\": -2.9329, \"times_seen\": null}, {\"site\": 902, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": null, \"functional effect\": -2.0613, \"times_seen\": null}, {\"site\": 903, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": null, \"functional effect\": -3.0814, \"times_seen\": null}, {\"site\": 904, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": null, \"functional effect\": -0.115, \"times_seen\": null}, {\"site\": 905, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": null, \"functional effect\": -2.5548, \"times_seen\": null}, {\"site\": 906, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": null, \"functional effect\": -2.9022, \"times_seen\": null}, {\"site\": 907, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": null, \"functional effect\": -2.9794, \"times_seen\": null}, {\"site\": 908, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": null, \"functional effect\": -2.9987, \"times_seen\": null}, {\"site\": 908, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": null, \"functional effect\": -1.1709, \"times_seen\": null}, {\"site\": 910, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": null, \"functional effect\": -2.375, \"times_seen\": null}, {\"site\": 910, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 910, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": null, \"functional effect\": -3.1312, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": -1.9481, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 911, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": -1.2052, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -3.1761, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -1.4918, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -2.9571, \"times_seen\": null}, {\"site\": 912, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -2.8687, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -2.3525, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -2.9718, \"times_seen\": null}, {\"site\": 913, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -3.0003, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -1.2773, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -2.9051, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -3.2613, \"times_seen\": null}, {\"site\": 914, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 915, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 916, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 916, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": null, \"functional effect\": -2.0581, \"times_seen\": null}, {\"site\": 916, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": null, \"functional effect\": -2.9814, \"times_seen\": null}, {\"site\": 917, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": null, \"functional effect\": -2.9981, \"times_seen\": null}, {\"site\": 917, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 917, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": null, \"functional effect\": -1.4999, \"times_seen\": null}, {\"site\": 918, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 918, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": null, \"functional effect\": -2.9992, \"times_seen\": null}, {\"site\": 919, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": null, \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 919, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 920, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": null, \"functional effect\": -3.0157, \"times_seen\": null}, {\"site\": 920, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": null, \"functional effect\": -1.6968, \"times_seen\": null}, {\"site\": 920, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": null, \"functional effect\": -3.0143, \"times_seen\": null}, {\"site\": 921, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": null, \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 922, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 923, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": null, \"functional effect\": -2.7711, \"times_seen\": null}, {\"site\": 923, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 924, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": null, \"functional effect\": -1.6718, \"times_seen\": null}, {\"site\": 924, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": null, \"functional effect\": -1.4792, \"times_seen\": null}, {\"site\": 925, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 925, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": null, \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 925, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 926, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": null, \"functional effect\": -2.9792, \"times_seen\": null}, {\"site\": 927, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": null, \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 928, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": null, \"functional effect\": -3.0956, \"times_seen\": null}, {\"site\": 928, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": null, \"functional effect\": -2.9437, \"times_seen\": null}, {\"site\": 930, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": null, \"functional effect\": -2.0862, \"times_seen\": null}, {\"site\": 930, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": null, \"functional effect\": -3.3409, \"times_seen\": null}, {\"site\": 931, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 931, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": null, \"functional effect\": -2.5924, \"times_seen\": null}, {\"site\": 932, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": null, \"functional effect\": -2.4683, \"times_seen\": null}, {\"site\": 932, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 933, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": -0.3044, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": 0.6679, \"times_seen\": null}, {\"site\": 934, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": -1.7045, \"times_seen\": null}, {\"site\": 935, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 935, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": null, \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 935, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": null, \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 936, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 937, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": null, \"functional effect\": -1.6109, \"times_seen\": null}, {\"site\": 939, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": null, \"functional effect\": -0.4675, \"times_seen\": null}, {\"site\": 941, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": null, \"functional effect\": -0.1028, \"times_seen\": null}, {\"site\": 944, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": null, \"functional effect\": 0.1167, \"times_seen\": null}, {\"site\": 945, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": null, \"functional effect\": -3.2637, \"times_seen\": null}, {\"site\": 946, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": null, \"functional effect\": -2.5809, \"times_seen\": null}, {\"site\": 946, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": null, \"functional effect\": -1.3087, \"times_seen\": null}, {\"site\": 948, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": null, \"functional effect\": -2.7742, \"times_seen\": null}, {\"site\": 949, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 950, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 950, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": null, \"functional effect\": -0.1214, \"times_seen\": null}, {\"site\": 950, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": null, \"functional effect\": -0.5388, \"times_seen\": null}, {\"site\": 952, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 952, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 952, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": null, \"functional effect\": -3.1284, \"times_seen\": null}, {\"site\": 953, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 953, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": null, \"functional effect\": -2.0292, \"times_seen\": null}, {\"site\": 954, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": null, \"functional effect\": -2.7546, \"times_seen\": null}, {\"site\": 954, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 954, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": null, \"functional effect\": -3.0958, \"times_seen\": null}, {\"site\": 955, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 955, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": null, \"functional effect\": -2.0828, \"times_seen\": null}, {\"site\": 955, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": null, \"functional effect\": -2.4826, \"times_seen\": null}, {\"site\": 956, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 957, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 957, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 957, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": null, \"functional effect\": -0.4506, \"times_seen\": null}, {\"site\": 958, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 958, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": null, \"functional effect\": -2.8991, \"times_seen\": null}, {\"site\": 959, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": null, \"functional effect\": -2.8229, \"times_seen\": null}, {\"site\": 959, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 960, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": null, \"functional effect\": -0.911, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": -0.2766, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": -0.712, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": 0.0708, \"times_seen\": null}, {\"site\": 962, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": -2.2766, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -2.6953, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -1.7631, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -2.6644, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -3.0577, \"times_seen\": null}, {\"site\": 963, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -2.7218, \"times_seen\": null}, {\"site\": 964, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": null, \"functional effect\": -1.7587, \"times_seen\": null}, {\"site\": 964, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": null, \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 965, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": null, \"functional effect\": -0.1442, \"times_seen\": null}, {\"site\": 966, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 967, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 967, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": null, \"functional effect\": -2.7936, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -2.792, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -2.8535, \"times_seen\": null}, {\"site\": 968, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -3.0508, \"times_seen\": null}, {\"site\": 969, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 969, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": null, \"functional effect\": -2.3768, \"times_seen\": null}, {\"site\": 969, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": null, \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 970, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 970, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": null, \"functional effect\": -2.0482, \"times_seen\": null}, {\"site\": 970, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": null, \"functional effect\": -0.1562, \"times_seen\": null}, {\"site\": 971, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": null, \"functional effect\": -2.9942, \"times_seen\": null}, {\"site\": 971, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": null, \"functional effect\": -1.0597, \"times_seen\": null}, {\"site\": 971, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": null, \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 972, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 974, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 974, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": null, \"functional effect\": -3.0155, \"times_seen\": null}, {\"site\": 975, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 975, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": null, \"functional effect\": -0.6369, \"times_seen\": null}, {\"site\": 975, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": null, \"functional effect\": -2.6303, \"times_seen\": null}, {\"site\": 976, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 976, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": null, \"functional effect\": -1.9653, \"times_seen\": null}, {\"site\": 976, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": null, \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -3.0261, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -2.7277, \"times_seen\": null}, {\"site\": 977, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -3.1298, \"times_seen\": null}, {\"site\": 978, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": null, \"functional effect\": -1.8075, \"times_seen\": null}, {\"site\": 979, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 980, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 980, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": null, \"functional effect\": -2.6466, \"times_seen\": null}, {\"site\": 980, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": null, \"functional effect\": -2.3742, \"times_seen\": null}, {\"site\": 982, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 982, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": null, \"functional effect\": -2.4547, \"times_seen\": null}, {\"site\": 984, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": null, \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 984, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": null, \"functional effect\": -2.6678, \"times_seen\": null}, {\"site\": 984, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": null, \"functional effect\": -2.3691, \"times_seen\": null}, {\"site\": 985, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": null, \"functional effect\": -1.4746, \"times_seen\": null}, {\"site\": 985, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": null, \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 986, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": null, \"functional effect\": -2.5603, \"times_seen\": null}, {\"site\": 986, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": null, \"functional effect\": -2.9982, \"times_seen\": null}, {\"site\": 987, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": null, \"functional effect\": -2.9304, \"times_seen\": null}, {\"site\": 989, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": null, \"functional effect\": -3.0082, \"times_seen\": null}, {\"site\": 989, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": null, \"functional effect\": -0.1337, \"times_seen\": null}, {\"site\": 989, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": null, \"functional effect\": -2.6481, \"times_seen\": null}, {\"site\": 990, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": null, \"functional effect\": -0.9604, \"times_seen\": null}, {\"site\": 991, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": null, \"functional effect\": -3.0081, \"times_seen\": null}, {\"site\": 991, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": null, \"functional effect\": -3.2113, \"times_seen\": null}, {\"site\": 992, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": null, \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 992, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": null, \"functional effect\": -3.0258, \"times_seen\": null}, {\"site\": 992, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": null, \"functional effect\": -2.9769, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.9947, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.71, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.9676, \"times_seen\": null}, {\"site\": 993, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.3938, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -1.7069, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -2.0252, \"times_seen\": null}, {\"site\": 994, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 996, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 996, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": null, \"functional effect\": -2.3833, \"times_seen\": null}, {\"site\": 996, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": null, \"functional effect\": -2.312, \"times_seen\": null}, {\"site\": 997, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": null, \"functional effect\": -2.983, \"times_seen\": null}, {\"site\": 998, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": null, \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 999, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": null, \"functional effect\": -1.1754, \"times_seen\": null}, {\"site\": 999, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": null, \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 1000, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": null, \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 1001, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": null, \"functional effect\": -2.086, \"times_seen\": null}, {\"site\": 1001, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": null, \"functional effect\": -3.137, \"times_seen\": null}, {\"site\": 1004, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": null, \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 1004, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": null, \"functional effect\": 1.2037, \"times_seen\": null}, {\"site\": 1004, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": null, \"functional effect\": 0.4014, \"times_seen\": null}, {\"site\": 1005, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": null, \"functional effect\": -3.1121, \"times_seen\": null}, {\"site\": 1006, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": null, \"functional effect\": -2.8706, \"times_seen\": null}, {\"site\": 1006, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": null, \"functional effect\": -3.2055, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": -2.956, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": -0.9976, \"times_seen\": null}, {\"site\": 1007, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": 0.0937, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": null, \"functional effect\": -2.674, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1008, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": null, \"functional effect\": -1.6132, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": null, \"functional effect\": -2.955, \"times_seen\": null}, {\"site\": 1009, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": null, \"functional effect\": -2.4856, \"times_seen\": null}, {\"site\": 1010, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1011, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1012, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1012, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": null, \"functional effect\": -0.4353, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": null, \"functional effect\": -3.0364, \"times_seen\": null}, {\"site\": 1013, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": null, \"functional effect\": 0.2801, \"times_seen\": null}, {\"site\": 1014, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": null, \"functional effect\": -0.7502, \"times_seen\": null}, {\"site\": 1014, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1015, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1018, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": null, \"functional effect\": -1.9687, \"times_seen\": null}, {\"site\": 1018, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": null, \"functional effect\": -1.5061, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": null, \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": null, \"functional effect\": -1.672, \"times_seen\": null}, {\"site\": 1019, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": null, \"functional effect\": -2.958, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": -2.2784, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": -3.0015, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": -0.7165, \"times_seen\": null}, {\"site\": 1022, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": null, \"functional effect\": -2.5221, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": null, \"functional effect\": -2.8854, \"times_seen\": null}, {\"site\": 1023, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1025, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": null, \"functional effect\": -1.3488, \"times_seen\": null}, {\"site\": 1025, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": null, \"functional effect\": -1.1122, \"times_seen\": null}, {\"site\": 1026, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1026, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": null, \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -2.028, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -3.1432, \"times_seen\": null}, {\"site\": 1027, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -1.0065, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -2.9215, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -3.0479, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 1028, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -2.9863, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.7992, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.9457, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -3.2569, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -3.0016, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 1029, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.9672, \"times_seen\": null}, {\"site\": 1030, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1030, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": null, \"functional effect\": -2.6421, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": null, \"functional effect\": -2.9507, \"times_seen\": null}, {\"site\": 1031, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": null, \"functional effect\": -0.8952, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": null, \"functional effect\": -2.7367, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1032, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": null, \"functional effect\": -2.744, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -1.6874, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 1033, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 1034, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1034, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": null, \"functional effect\": -2.9471, \"times_seen\": null}, {\"site\": 1035, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1035, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": null, \"functional effect\": 0.1395, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -2.5103, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 1036, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -3.1583, \"times_seen\": null}, {\"site\": 1037, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1038, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.7063, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.9171, \"times_seen\": null}, {\"site\": 1039, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.3389, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -2.9823, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -3.0004, \"times_seen\": null}, {\"site\": 1040, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -0.4876, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": null, \"functional effect\": -3.0044, \"times_seen\": null}, {\"site\": 1041, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": null, \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1042, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": null, \"functional effect\": -1.1639, \"times_seen\": null}, {\"site\": 1043, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": null, \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 1044, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1044, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1044, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": null, \"functional effect\": -3.3118, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -3.26, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -3.0083, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -2.8866, \"times_seen\": null}, {\"site\": 1045, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1046, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1046, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": null, \"functional effect\": -2.3805, \"times_seen\": null}, {\"site\": 1047, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": null, \"functional effect\": -2.7832, \"times_seen\": null}, {\"site\": 1048, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": null, \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.999, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.7168, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.9766, \"times_seen\": null}, {\"site\": 1051, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.5057, \"times_seen\": null}, {\"site\": 1052, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": null, \"functional effect\": -3.1635, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": null, \"functional effect\": -3.265, \"times_seen\": null}, {\"site\": 1053, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1055, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": null, \"functional effect\": -1.911, \"times_seen\": null}, {\"site\": 1055, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": null, \"functional effect\": -0.4864, \"times_seen\": null}, {\"site\": 1057, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": null, \"functional effect\": -2.9006, \"times_seen\": null}, {\"site\": 1058, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": null, \"functional effect\": -0.3743, \"times_seen\": null}, {\"site\": 1059, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": null, \"functional effect\": -3.053, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": null, \"functional effect\": -2.6745, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": null, \"functional effect\": -2.4501, \"times_seen\": null}, {\"site\": 1061, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": null, \"functional effect\": -1.8627, \"times_seen\": null}, {\"site\": 1062, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": null, \"functional effect\": -0.9906, \"times_seen\": null}, {\"site\": 1062, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": null, \"functional effect\": -2.9248, \"times_seen\": null}, {\"site\": 1063, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": null, \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -3.1347, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -1.8727, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -2.9832, \"times_seen\": null}, {\"site\": 1064, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -3.0924, \"times_seen\": null}, {\"site\": 1065, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": null, \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1066, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": null, \"functional effect\": -2.9985, \"times_seen\": null}, {\"site\": 1067, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": null, \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 1067, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": null, \"functional effect\": -3.0417, \"times_seen\": null}, {\"site\": 1068, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": null, \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 1068, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": null, \"functional effect\": -2.9223, \"times_seen\": null}, {\"site\": 1069, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1070, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1071, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1072, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1072, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": null, \"functional effect\": -2.793, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -2.5151, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -2.8967, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -0.9705, \"times_seen\": null}, {\"site\": 1074, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1075, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": null, \"functional effect\": -2.8288, \"times_seen\": null}, {\"site\": 1075, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": null, \"functional effect\": -3.1007, \"times_seen\": null}, {\"site\": 1076, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": null, \"functional effect\": -0.3029, \"times_seen\": null}, {\"site\": 1076, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": null, \"functional effect\": -3.2643, \"times_seen\": null}, {\"site\": 1077, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": null, \"functional effect\": -0.3397, \"times_seen\": null}, {\"site\": 1077, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": null, \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1078, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": null, \"functional effect\": -3.0036, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -3.0716, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -3.0067, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -2.2886, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1079, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1080, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": null, \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1080, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1081, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": null, \"functional effect\": -0.189, \"times_seen\": null}, {\"site\": 1081, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": null, \"functional effect\": -0.0339, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": null, \"functional effect\": -3.0347, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1083, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": null, \"functional effect\": -0.4516, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": null, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": null, \"functional effect\": -2.078, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": null, \"functional effect\": -1.4293, \"times_seen\": null}, {\"site\": 1084, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": null, \"functional effect\": -1.5309, \"times_seen\": null}, {\"site\": 1085, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": null, \"functional effect\": -1.2344, \"times_seen\": null}, {\"site\": 1086, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": null, \"functional effect\": -3.1209, \"times_seen\": null}, {\"site\": 1086, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": null, \"functional effect\": -0.1576, \"times_seen\": null}, {\"site\": 1087, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": null, \"functional effect\": -1.166, \"times_seen\": null}, {\"site\": 1088, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": null, \"functional effect\": -3.1836, \"times_seen\": null}, {\"site\": 1089, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": null, \"functional effect\": -2.1064, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": null, \"functional effect\": -0.8553, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": null, \"functional effect\": -0.3222, \"times_seen\": null}, {\"site\": 1090, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": null, \"functional effect\": -2.3225, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": null, \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": null, \"functional effect\": -2.9443, \"times_seen\": null}, {\"site\": 1092, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": null, \"functional effect\": -1.1874, \"times_seen\": null}, {\"site\": 1093, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": null, \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1094, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": null, \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1095, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": null, \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1095, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1096, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": null, \"functional effect\": -1.4413, \"times_seen\": null}, {\"site\": 1098, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1098, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1099, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": null, \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 1099, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": null, \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1100, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1100, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": null, \"functional effect\": 0.0507, \"times_seen\": null}, {\"site\": 1101, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": null, \"functional effect\": -2.867, \"times_seen\": null}, {\"site\": 1102, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": null, \"functional effect\": -2.6567, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": null, \"functional effect\": -2.0867, \"times_seen\": null}, {\"site\": 1103, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": null, \"functional effect\": -2.7148, \"times_seen\": null}, {\"site\": 1104, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1105, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": null, \"functional effect\": -1.8012, \"times_seen\": null}, {\"site\": 1106, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": null, \"functional effect\": -2.9219, \"times_seen\": null}, {\"site\": 1107, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": null, \"functional effect\": -1.6801, \"times_seen\": null}, {\"site\": 1107, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": null, \"functional effect\": -3.1111, \"times_seen\": null}, {\"site\": 1108, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": null, \"functional effect\": -2.946, \"times_seen\": null}, {\"site\": 1110, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": null, \"functional effect\": -2.7803, \"times_seen\": null}, {\"site\": 1112, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": null, \"functional effect\": -2.671, \"times_seen\": null}, {\"site\": 1116, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": null, \"functional effect\": -2.7984, \"times_seen\": null}, {\"site\": 1116, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": null, \"functional effect\": -3.2216, \"times_seen\": null}, {\"site\": 1118, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": null, \"functional effect\": -2.5171, \"times_seen\": null}, {\"site\": 1120, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -3.2598, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -2.9886, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -3.1257, \"times_seen\": null}, {\"site\": 1123, \"wildtype\": null, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 1125, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": null, \"functional effect\": -2.7083, \"times_seen\": null}, {\"site\": 1126, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": null, \"functional effect\": -2.4619, \"times_seen\": null}, {\"site\": 1126, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": null, \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 1127, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": null, \"functional effect\": -3.0159, \"times_seen\": null}, {\"site\": 1128, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": null, \"functional effect\": -2.5563, \"times_seen\": null}, {\"site\": 1128, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": null, \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 1129, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": null, \"functional effect\": -0.3274, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": -0.2697, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": -2.0997, \"times_seen\": null}, {\"site\": 1130, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 1131, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1132, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1133, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1133, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1133, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": null, \"functional effect\": 0.8711, \"times_seen\": null}, {\"site\": 1135, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": null, \"functional effect\": -2.7638, \"times_seen\": null}, {\"site\": 1135, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": null, \"functional effect\": -1.1135, \"times_seen\": null}, {\"site\": 1136, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1137, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1138, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1139, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1139, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": null, \"functional effect\": -1.9059, \"times_seen\": null}, {\"site\": 1140, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1142, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": null, \"functional effect\": -1.545, \"times_seen\": null}, {\"site\": 1142, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": null, \"functional effect\": -2.4853, \"times_seen\": null}, {\"site\": 1143, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1143, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": null, \"functional effect\": -0.8795, \"times_seen\": null}, {\"site\": 1144, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1145, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1145, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": null, \"functional effect\": -2.774, \"times_seen\": null}, {\"site\": 1146, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1147, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": null, \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1148, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": null, \"functional effect\": -2.9483, \"times_seen\": null}, {\"site\": 1148, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": null, \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": null, \"functional effect\": -2.1789, \"times_seen\": null}, {\"site\": 1149, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": null, \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 1151, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1152, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": null, \"functional effect\": -2.0697, \"times_seen\": null}, {\"site\": 1152, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": null, \"functional effect\": -0.7103, \"times_seen\": null}, {\"site\": 1153, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": null, \"functional effect\": -2.8933, \"times_seen\": null}, {\"site\": 1154, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": null, \"functional effect\": -2.8081, \"times_seen\": null}, {\"site\": 1154, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1157, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": null, \"functional effect\": -2.9246, \"times_seen\": null}, {\"site\": 1158, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": null, \"functional effect\": -1.62, \"times_seen\": null}, {\"site\": 1158, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": null, \"functional effect\": -0.0525, \"times_seen\": null}, {\"site\": 1161, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1163, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": null, \"functional effect\": -0.1077, \"times_seen\": null}, {\"site\": 1163, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": null, \"functional effect\": -3.2137, \"times_seen\": null}, {\"site\": 1166, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": null, \"functional effect\": -3.1213, \"times_seen\": null}, {\"site\": 1166, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": null, \"functional effect\": -0.2359, \"times_seen\": null}, {\"site\": 1167, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": null, \"functional effect\": -0.391, \"times_seen\": null}, {\"site\": 1168, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": null, \"functional effect\": 0.1459, \"times_seen\": null}, {\"site\": 1168, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": null, \"functional effect\": -1.695, \"times_seen\": null}, {\"site\": 1169, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1171, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": null, \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1172, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": null, \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1172, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": null, \"functional effect\": -2.0152, \"times_seen\": null}, {\"site\": 1174, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": null, \"functional effect\": 0.2962, \"times_seen\": null}, {\"site\": 1175, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1176, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1177, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": null, \"functional effect\": -3.1214, \"times_seen\": null}, {\"site\": 1178, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": null, \"functional effect\": -0.1879, \"times_seen\": null}, {\"site\": 1179, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": null, \"functional effect\": -2.8676, \"times_seen\": null}, {\"site\": 1179, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1180, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1180, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": null, \"functional effect\": -3.2623, \"times_seen\": null}, {\"site\": 1181, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1181, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": null, \"functional effect\": -2.8217, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": null, \"functional effect\": -3.1155, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1182, \"wildtype\": null, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1183, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": null, \"functional effect\": -1.4169, \"times_seen\": null}, {\"site\": 1184, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1185, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1186, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1186, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": null, \"functional effect\": -2.9313, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": null, \"functional effect\": -0.126, \"times_seen\": null}, {\"site\": 1187, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": null, \"functional effect\": -3.2974, \"times_seen\": null}, {\"site\": 1188, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1189, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": null, \"functional effect\": -1.1747, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -2.8743, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -3.1097, \"times_seen\": null}, {\"site\": 1190, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -1.4736, \"times_seen\": null}, {\"site\": 1191, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1192, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -2.8134, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -0.9579, \"times_seen\": null}, {\"site\": 1193, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -3.2983, \"times_seen\": null}, {\"site\": 1194, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": null, \"functional effect\": -0.7933, \"times_seen\": null}, {\"site\": 1195, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": null, \"functional effect\": -2.2422, \"times_seen\": null}, {\"site\": 1195, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": null, \"functional effect\": -2.8804, \"times_seen\": null}, {\"site\": 1197, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": null, \"functional effect\": -2.949, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1198, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1199, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1200, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1201, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1202, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1204, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": null, \"functional effect\": -0.2522, \"times_seen\": null}, {\"site\": 1205, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": null, \"functional effect\": -2.8389, \"times_seen\": null}, {\"site\": 1205, \"wildtype\": null, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": null, \"functional effect\": -0.8033, \"times_seen\": null}, {\"site\": 1206, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": null, \"functional effect\": -2.9748, \"times_seen\": null}, {\"site\": 1206, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1206, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": null, \"functional effect\": -0.5447, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": null, \"functional effect\": -2.6414, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1207, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": null, \"functional effect\": -1.3902, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": -2.8901, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": 1.3076, \"times_seen\": null}, {\"site\": 1208, \"wildtype\": null, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": -0.9017, \"times_seen\": null}, {\"site\": 1209, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1210, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": null, \"functional effect\": -0.9333, \"times_seen\": null}, {\"site\": 1210, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": null, \"functional effect\": -1.1673, \"times_seen\": null}, {\"site\": 1211, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1212, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": null, \"functional effect\": -3.1551, \"times_seen\": null}, {\"site\": 1212, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1213, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1213, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": null, \"functional effect\": -0.4976, \"times_seen\": null}, {\"site\": 1214, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1214, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": null, \"functional effect\": -1.5744, \"times_seen\": null}, {\"site\": 1214, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": null, \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 1215, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1215, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": null, \"functional effect\": -2.8079, \"times_seen\": null}, {\"site\": 1216, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1217, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1217, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": null, \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 1218, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1218, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": null, \"functional effect\": -0.4574, \"times_seen\": null}, {\"site\": 1219, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": null, \"functional effect\": -2.9327, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1220, \"wildtype\": null, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": null, \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 1221, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1221, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": null, \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 1222, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1223, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1223, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": null, \"functional effect\": -0.4402, \"times_seen\": null}, {\"site\": 1224, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": null, \"functional effect\": -1.7015, \"times_seen\": null}, {\"site\": 1224, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": null, \"functional effect\": -1.1773, \"times_seen\": null}, {\"site\": 1227, \"wildtype\": null, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": null, \"functional effect\": -2.0124, \"times_seen\": null}, {\"site\": 1229, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": null, \"functional effect\": -0.882, \"times_seen\": null}, {\"site\": 1230, \"wildtype\": null, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": null, \"functional effect\": -1.8772, \"times_seen\": null}, {\"site\": 1231, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": null, \"functional effect\": -0.2956, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": null, \"functional effect\": -0.0671, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": null, \"functional effect\": -0.5153, \"times_seen\": null}, {\"site\": 1232, \"wildtype\": null, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": null, \"functional effect\": -1.4835, \"times_seen\": null}, {\"site\": 1233, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": null, \"functional effect\": -1.6538, \"times_seen\": null}, {\"site\": 1235, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": null, \"functional effect\": -0.5267, \"times_seen\": null}, {\"site\": 1236, \"wildtype\": null, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": null, \"functional effect\": -2.9838, \"times_seen\": null}, {\"site\": 1238, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": null, \"functional effect\": -0.8018, \"times_seen\": null}, {\"site\": 1239, \"wildtype\": null, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": null, \"functional effect\": -0.2083, \"times_seen\": null}, {\"site\": 1239, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": null, \"functional effect\": -1.4432, \"times_seen\": null}, {\"site\": 1242, \"wildtype\": null, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": null, \"functional effect\": -1.5664, \"times_seen\": null}, {\"site\": 1242, \"wildtype\": null, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": null, \"functional effect\": -2.3704, \"times_seen\": null}, {\"site\": 1243, \"wildtype\": null, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": null, \"functional effect\": -0.3658, \"times_seen\": null}, {\"site\": 1245, \"wildtype\": null, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": null, \"functional effect\": -0.5006, \"times_seen\": null}, {\"site\": 1246, \"wildtype\": null, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": null, \"functional effect\": -0.079, \"times_seen\": null}, {\"site\": 1246, \"wildtype\": null, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": null, \"functional effect\": -0.0951, \"times_seen\": null}, {\"site\": 1247, \"wildtype\": null, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": null, \"functional effect\": -0.4455, \"times_seen\": null}, {\"site\": 1247, \"wildtype\": null, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": null, \"functional effect\": 0.6552, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": null, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": null, \"functional effect\": -0.3058, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": null, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1250, \"wildtype\": null, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-9631765c1c8eedabe994b76062594ede\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_5\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"all\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}}, \"name\": \"view_4\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_6 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_7 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.608964415398025,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_9\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"all\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site log2 fold change IC90\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_6 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_7 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.608964415398025,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-6f4dc25935552d92129204611ad6a7c2\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_6\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_6 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_7 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.608964415398025,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"log2 fold change IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_6 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_7 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.608964415398025,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum['epitope'] === 'all')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"log2 fold change IC90\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 10.085972808762458, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"log2 fold change IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"IC90\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_6 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_7 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.608964415398025,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum['epitope'] === 'all')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-fec33ae205ff6712775e4252a9254f06\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['log2 fold change IC90']),datum['log2 fold change IC90'],NaN)\", \"as\": \"log2 fold change IC90\"}, {\"calculate\": \"if(isFinite(datum['IC90']),datum['IC90'],NaN)\", \"as\": \"IC90\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['log2 fold change IC90'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_6 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_7 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-6.608964415398025,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-6f4dc25935552d92129204611ad6a7c2\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_10\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_5\", \"view_4\", \"view_6\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site log2 fold change IC90 statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_4\"]}, {\"name\": \"param_9\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_4\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -6.608964415398025], \"labels\": [\"yes\", \"no\"], \"name\": \"floor log2 fold change IC90 at zero\"}, \"value\": [{\"floor\": -6.608964415398025}], \"views\": [\"view_5\", \"view_4\", \"view_6\"]}, {\"name\": \"param_6\", \"bind\": {\"input\": \"range\", \"max\": 1.5161, \"min\": -3.3409, \"name\": \"minimum functional effect\"}, \"value\": -3.3409}, {\"name\": \"param_7\", \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": 1}, {\"name\": \"param_8\", \"bind\": {\"input\": \"range\", \"max\": 10.085972808762458, \"min\": -6.608964415398025, \"name\": \"minimum max of log2 fold change IC90 at site\"}, \"value\": -6.608964415398025}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-9631765c1c8eedabe994b76062594ede\": [{\"site\": 1, \"_stat_site_order\": 0}, {\"site\": 2, \"_stat_site_order\": 1}, {\"site\": 3, \"_stat_site_order\": 2}, {\"site\": 4, \"_stat_site_order\": 3}, {\"site\": 5, \"_stat_site_order\": 4}, {\"site\": 6, \"_stat_site_order\": 5}, {\"site\": 7, \"_stat_site_order\": 6}, {\"site\": 8, \"_stat_site_order\": 7}, {\"site\": 9, \"_stat_site_order\": 8}, {\"site\": 10, \"_stat_site_order\": 9}, {\"site\": 11, \"_stat_site_order\": 10}, {\"site\": 12, \"_stat_site_order\": 11}, {\"site\": 13, \"_stat_site_order\": 12}, {\"site\": 14, \"_stat_site_order\": 13}, {\"site\": 15, \"_stat_site_order\": 14}, {\"site\": 16, \"_stat_site_order\": 15}, {\"site\": 17, \"_stat_site_order\": 16}, {\"site\": 18, \"_stat_site_order\": 17}, {\"site\": 19, \"_stat_site_order\": 18}, {\"site\": 20, \"_stat_site_order\": 19}, {\"site\": 21, \"_stat_site_order\": 20}, {\"site\": 22, \"_stat_site_order\": 21}, {\"site\": 23, \"_stat_site_order\": 22}, {\"site\": 24, \"_stat_site_order\": 23}, {\"site\": 25, \"_stat_site_order\": 24}, {\"site\": 26, \"_stat_site_order\": 25}, {\"site\": 27, \"_stat_site_order\": 26}, {\"site\": 28, \"_stat_site_order\": 27}, {\"site\": 29, \"_stat_site_order\": 28}, {\"site\": 30, \"_stat_site_order\": 29}, {\"site\": 31, \"_stat_site_order\": 30}, {\"site\": 32, \"_stat_site_order\": 31}, {\"site\": 33, \"_stat_site_order\": 32}, {\"site\": 34, \"_stat_site_order\": 33}, {\"site\": 35, \"_stat_site_order\": 34}, {\"site\": 36, \"_stat_site_order\": 35}, {\"site\": 37, \"_stat_site_order\": 36}, {\"site\": 38, \"_stat_site_order\": 37}, {\"site\": 39, \"_stat_site_order\": 38}, {\"site\": 40, \"_stat_site_order\": 39}, {\"site\": 41, \"_stat_site_order\": 40}, {\"site\": 42, \"_stat_site_order\": 41}, {\"site\": 43, \"_stat_site_order\": 42}, {\"site\": 44, \"_stat_site_order\": 43}, {\"site\": 45, \"_stat_site_order\": 44}, {\"site\": 46, \"_stat_site_order\": 45}, {\"site\": 47, \"_stat_site_order\": 46}, {\"site\": 48, \"_stat_site_order\": 47}, {\"site\": 49, \"_stat_site_order\": 48}, {\"site\": 50, \"_stat_site_order\": 49}, {\"site\": 51, \"_stat_site_order\": 50}, {\"site\": 52, \"_stat_site_order\": 51}, {\"site\": 53, \"_stat_site_order\": 52}, {\"site\": 54, \"_stat_site_order\": 53}, {\"site\": 55, \"_stat_site_order\": 54}, {\"site\": 56, \"_stat_site_order\": 55}, {\"site\": 57, \"_stat_site_order\": 56}, {\"site\": 58, \"_stat_site_order\": 57}, {\"site\": 59, \"_stat_site_order\": 58}, {\"site\": 60, \"_stat_site_order\": 59}, {\"site\": 61, \"_stat_site_order\": 60}, {\"site\": 62, \"_stat_site_order\": 61}, {\"site\": 63, \"_stat_site_order\": 62}, {\"site\": 64, \"_stat_site_order\": 63}, {\"site\": 65, \"_stat_site_order\": 64}, {\"site\": 66, \"_stat_site_order\": 65}, {\"site\": 67, \"_stat_site_order\": 66}, {\"site\": 68, \"_stat_site_order\": 67}, {\"site\": 69, \"_stat_site_order\": 68}, {\"site\": 70, \"_stat_site_order\": 69}, {\"site\": 71, \"_stat_site_order\": 70}, {\"site\": 72, \"_stat_site_order\": 71}, {\"site\": 73, \"_stat_site_order\": 72}, {\"site\": 74, \"_stat_site_order\": 73}, {\"site\": 75, \"_stat_site_order\": 74}, {\"site\": 76, \"_stat_site_order\": 75}, {\"site\": 77, \"_stat_site_order\": 76}, {\"site\": 78, \"_stat_site_order\": 77}, {\"site\": 79, \"_stat_site_order\": 78}, {\"site\": 80, \"_stat_site_order\": 79}, {\"site\": 81, \"_stat_site_order\": 80}, {\"site\": 82, \"_stat_site_order\": 81}, {\"site\": 83, \"_stat_site_order\": 82}, {\"site\": 84, \"_stat_site_order\": 83}, {\"site\": 85, \"_stat_site_order\": 84}, {\"site\": 86, \"_stat_site_order\": 85}, {\"site\": 87, \"_stat_site_order\": 86}, {\"site\": 88, \"_stat_site_order\": 87}, {\"site\": 89, \"_stat_site_order\": 88}, {\"site\": 90, \"_stat_site_order\": 89}, {\"site\": 91, \"_stat_site_order\": 90}, {\"site\": 92, \"_stat_site_order\": 91}, {\"site\": 93, \"_stat_site_order\": 92}, {\"site\": 94, \"_stat_site_order\": 93}, {\"site\": 95, \"_stat_site_order\": 94}, {\"site\": 96, \"_stat_site_order\": 95}, {\"site\": 97, \"_stat_site_order\": 96}, {\"site\": 98, \"_stat_site_order\": 97}, {\"site\": 99, \"_stat_site_order\": 98}, {\"site\": 100, \"_stat_site_order\": 99}, {\"site\": 101, \"_stat_site_order\": 100}, {\"site\": 102, \"_stat_site_order\": 101}, {\"site\": 103, \"_stat_site_order\": 102}, {\"site\": 104, \"_stat_site_order\": 103}, {\"site\": 105, \"_stat_site_order\": 104}, {\"site\": 106, \"_stat_site_order\": 105}, {\"site\": 107, \"_stat_site_order\": 106}, {\"site\": 108, \"_stat_site_order\": 107}, {\"site\": 109, \"_stat_site_order\": 108}, {\"site\": 110, \"_stat_site_order\": 109}, {\"site\": 111, \"_stat_site_order\": 110}, {\"site\": 112, \"_stat_site_order\": 111}, {\"site\": 113, \"_stat_site_order\": 112}, {\"site\": 114, \"_stat_site_order\": 113}, {\"site\": 115, \"_stat_site_order\": 114}, {\"site\": 116, \"_stat_site_order\": 115}, {\"site\": 117, \"_stat_site_order\": 116}, {\"site\": 118, \"_stat_site_order\": 117}, {\"site\": 119, \"_stat_site_order\": 118}, {\"site\": 120, \"_stat_site_order\": 119}, {\"site\": 121, \"_stat_site_order\": 120}, {\"site\": 122, \"_stat_site_order\": 121}, {\"site\": 123, \"_stat_site_order\": 122}, {\"site\": 124, \"_stat_site_order\": 123}, {\"site\": 125, \"_stat_site_order\": 124}, {\"site\": 126, \"_stat_site_order\": 125}, {\"site\": 127, \"_stat_site_order\": 126}, {\"site\": 128, \"_stat_site_order\": 127}, {\"site\": 129, \"_stat_site_order\": 128}, {\"site\": 130, \"_stat_site_order\": 129}, {\"site\": 131, \"_stat_site_order\": 130}, {\"site\": 132, \"_stat_site_order\": 131}, {\"site\": 133, \"_stat_site_order\": 132}, {\"site\": 134, \"_stat_site_order\": 133}, {\"site\": 135, \"_stat_site_order\": 134}, {\"site\": 136, \"_stat_site_order\": 135}, {\"site\": 137, \"_stat_site_order\": 136}, {\"site\": 138, \"_stat_site_order\": 137}, {\"site\": 139, \"_stat_site_order\": 138}, {\"site\": 140, \"_stat_site_order\": 139}, {\"site\": 141, \"_stat_site_order\": 140}, {\"site\": 142, \"_stat_site_order\": 141}, {\"site\": 143, \"_stat_site_order\": 142}, {\"site\": 144, \"_stat_site_order\": 143}, {\"site\": 145, \"_stat_site_order\": 144}, {\"site\": 146, \"_stat_site_order\": 145}, {\"site\": 147, \"_stat_site_order\": 146}, {\"site\": 148, \"_stat_site_order\": 147}, {\"site\": 149, \"_stat_site_order\": 148}, {\"site\": 150, \"_stat_site_order\": 149}, {\"site\": 151, \"_stat_site_order\": 150}, {\"site\": 152, \"_stat_site_order\": 151}, {\"site\": 153, \"_stat_site_order\": 152}, {\"site\": 154, \"_stat_site_order\": 153}, {\"site\": 155, \"_stat_site_order\": 154}, {\"site\": 156, \"_stat_site_order\": 155}, {\"site\": 157, \"_stat_site_order\": 156}, {\"site\": 158, \"_stat_site_order\": 157}, {\"site\": 159, \"_stat_site_order\": 158}, {\"site\": 160, \"_stat_site_order\": 159}, {\"site\": 161, \"_stat_site_order\": 160}, {\"site\": 162, \"_stat_site_order\": 161}, {\"site\": 163, \"_stat_site_order\": 162}, {\"site\": 164, \"_stat_site_order\": 163}, {\"site\": 165, \"_stat_site_order\": 164}, {\"site\": 166, \"_stat_site_order\": 165}, {\"site\": 167, \"_stat_site_order\": 166}, {\"site\": 168, \"_stat_site_order\": 167}, {\"site\": 169, \"_stat_site_order\": 168}, {\"site\": 170, \"_stat_site_order\": 169}, {\"site\": 171, \"_stat_site_order\": 170}, {\"site\": 172, \"_stat_site_order\": 171}, {\"site\": 173, \"_stat_site_order\": 172}, {\"site\": 174, \"_stat_site_order\": 173}, {\"site\": 175, \"_stat_site_order\": 174}, {\"site\": 176, \"_stat_site_order\": 175}, {\"site\": 177, \"_stat_site_order\": 176}, {\"site\": 178, \"_stat_site_order\": 177}, {\"site\": 179, \"_stat_site_order\": 178}, {\"site\": 180, \"_stat_site_order\": 179}, {\"site\": 181, \"_stat_site_order\": 180}, {\"site\": 182, \"_stat_site_order\": 181}, {\"site\": 183, \"_stat_site_order\": 182}, {\"site\": 184, \"_stat_site_order\": 183}, {\"site\": 185, \"_stat_site_order\": 184}, {\"site\": 186, \"_stat_site_order\": 185}, {\"site\": 187, \"_stat_site_order\": 186}, {\"site\": 188, \"_stat_site_order\": 187}, {\"site\": 189, \"_stat_site_order\": 188}, {\"site\": 190, \"_stat_site_order\": 189}, {\"site\": 191, \"_stat_site_order\": 190}, {\"site\": 192, \"_stat_site_order\": 191}, {\"site\": 193, \"_stat_site_order\": 192}, {\"site\": 194, \"_stat_site_order\": 193}, {\"site\": 195, \"_stat_site_order\": 194}, {\"site\": 196, \"_stat_site_order\": 195}, {\"site\": 197, \"_stat_site_order\": 196}, {\"site\": 198, \"_stat_site_order\": 197}, {\"site\": 199, \"_stat_site_order\": 198}, {\"site\": 200, \"_stat_site_order\": 199}, {\"site\": 201, \"_stat_site_order\": 200}, {\"site\": 202, \"_stat_site_order\": 201}, {\"site\": 203, \"_stat_site_order\": 202}, {\"site\": 204, \"_stat_site_order\": 203}, {\"site\": 205, \"_stat_site_order\": 204}, {\"site\": 206, \"_stat_site_order\": 205}, {\"site\": 207, \"_stat_site_order\": 206}, {\"site\": 208, \"_stat_site_order\": 207}, {\"site\": 209, \"_stat_site_order\": 208}, {\"site\": 210, \"_stat_site_order\": 209}, {\"site\": 211, \"_stat_site_order\": 210}, {\"site\": 212, \"_stat_site_order\": 211}, {\"site\": 213, \"_stat_site_order\": 212}, {\"site\": 214, \"_stat_site_order\": 213}, {\"site\": 215, \"_stat_site_order\": 214}, {\"site\": 216, \"_stat_site_order\": 215}, {\"site\": 217, \"_stat_site_order\": 216}, {\"site\": 218, \"_stat_site_order\": 217}, {\"site\": 219, \"_stat_site_order\": 218}, {\"site\": 220, \"_stat_site_order\": 219}, {\"site\": 221, \"_stat_site_order\": 220}, {\"site\": 222, \"_stat_site_order\": 221}, {\"site\": 223, \"_stat_site_order\": 222}, {\"site\": 224, \"_stat_site_order\": 223}, {\"site\": 225, \"_stat_site_order\": 224}, {\"site\": 226, \"_stat_site_order\": 225}, {\"site\": 227, \"_stat_site_order\": 226}, {\"site\": 228, \"_stat_site_order\": 227}, {\"site\": 229, \"_stat_site_order\": 228}, {\"site\": 230, \"_stat_site_order\": 229}, {\"site\": 231, \"_stat_site_order\": 230}, {\"site\": 232, \"_stat_site_order\": 231}, {\"site\": 233, \"_stat_site_order\": 232}, {\"site\": 234, \"_stat_site_order\": 233}, {\"site\": 235, \"_stat_site_order\": 234}, {\"site\": 236, \"_stat_site_order\": 235}, {\"site\": 237, \"_stat_site_order\": 236}, {\"site\": 238, \"_stat_site_order\": 237}, {\"site\": 239, \"_stat_site_order\": 238}, {\"site\": 240, \"_stat_site_order\": 239}, {\"site\": 241, \"_stat_site_order\": 240}, {\"site\": 242, \"_stat_site_order\": 241}, {\"site\": 243, \"_stat_site_order\": 242}, {\"site\": 244, \"_stat_site_order\": 243}, {\"site\": 245, \"_stat_site_order\": 244}, {\"site\": 246, \"_stat_site_order\": 245}, {\"site\": 247, \"_stat_site_order\": 246}, {\"site\": 248, \"_stat_site_order\": 247}, {\"site\": 249, \"_stat_site_order\": 248}, {\"site\": 250, \"_stat_site_order\": 249}, {\"site\": 251, \"_stat_site_order\": 250}, {\"site\": 252, \"_stat_site_order\": 251}, {\"site\": 253, \"_stat_site_order\": 252}, {\"site\": 254, \"_stat_site_order\": 253}, {\"site\": 255, \"_stat_site_order\": 254}, {\"site\": 256, \"_stat_site_order\": 255}, {\"site\": 257, \"_stat_site_order\": 256}, {\"site\": 258, \"_stat_site_order\": 257}, {\"site\": 259, \"_stat_site_order\": 258}, {\"site\": 260, \"_stat_site_order\": 259}, {\"site\": 261, \"_stat_site_order\": 260}, {\"site\": 262, \"_stat_site_order\": 261}, {\"site\": 263, \"_stat_site_order\": 262}, {\"site\": 264, \"_stat_site_order\": 263}, {\"site\": 265, \"_stat_site_order\": 264}, {\"site\": 266, \"_stat_site_order\": 265}, {\"site\": 267, \"_stat_site_order\": 266}, {\"site\": 268, \"_stat_site_order\": 267}, {\"site\": 269, \"_stat_site_order\": 268}, {\"site\": 270, \"_stat_site_order\": 269}, {\"site\": 271, \"_stat_site_order\": 270}, {\"site\": 272, \"_stat_site_order\": 271}, {\"site\": 273, \"_stat_site_order\": 272}, {\"site\": 274, \"_stat_site_order\": 273}, {\"site\": 275, \"_stat_site_order\": 274}, {\"site\": 276, \"_stat_site_order\": 275}, {\"site\": 277, \"_stat_site_order\": 276}, {\"site\": 278, \"_stat_site_order\": 277}, {\"site\": 279, \"_stat_site_order\": 278}, {\"site\": 280, \"_stat_site_order\": 279}, {\"site\": 281, \"_stat_site_order\": 280}, {\"site\": 282, \"_stat_site_order\": 281}, {\"site\": 283, \"_stat_site_order\": 282}, {\"site\": 284, \"_stat_site_order\": 283}, {\"site\": 285, \"_stat_site_order\": 284}, {\"site\": 286, \"_stat_site_order\": 285}, {\"site\": 287, \"_stat_site_order\": 286}, {\"site\": 288, \"_stat_site_order\": 287}, {\"site\": 289, \"_stat_site_order\": 288}, {\"site\": 290, \"_stat_site_order\": 289}, {\"site\": 291, \"_stat_site_order\": 290}, {\"site\": 292, \"_stat_site_order\": 291}, {\"site\": 293, \"_stat_site_order\": 292}, {\"site\": 294, \"_stat_site_order\": 293}, {\"site\": 295, \"_stat_site_order\": 294}, {\"site\": 296, \"_stat_site_order\": 295}, {\"site\": 297, \"_stat_site_order\": 296}, {\"site\": 298, \"_stat_site_order\": 297}, {\"site\": 299, \"_stat_site_order\": 298}, {\"site\": 300, \"_stat_site_order\": 299}, {\"site\": 301, \"_stat_site_order\": 300}, {\"site\": 302, \"_stat_site_order\": 301}, {\"site\": 303, \"_stat_site_order\": 302}, {\"site\": 304, \"_stat_site_order\": 303}, {\"site\": 305, \"_stat_site_order\": 304}, {\"site\": 306, \"_stat_site_order\": 305}, {\"site\": 307, \"_stat_site_order\": 306}, {\"site\": 308, \"_stat_site_order\": 307}, {\"site\": 309, \"_stat_site_order\": 308}, {\"site\": 310, \"_stat_site_order\": 309}, {\"site\": 311, \"_stat_site_order\": 310}, {\"site\": 312, \"_stat_site_order\": 311}, {\"site\": 313, \"_stat_site_order\": 312}, {\"site\": 314, \"_stat_site_order\": 313}, {\"site\": 315, \"_stat_site_order\": 314}, {\"site\": 316, \"_stat_site_order\": 315}, {\"site\": 317, \"_stat_site_order\": 316}, {\"site\": 318, \"_stat_site_order\": 317}, {\"site\": 319, \"_stat_site_order\": 318}, {\"site\": 320, \"_stat_site_order\": 319}, {\"site\": 321, \"_stat_site_order\": 320}, {\"site\": 322, \"_stat_site_order\": 321}, {\"site\": 323, \"_stat_site_order\": 322}, {\"site\": 324, \"_stat_site_order\": 323}, {\"site\": 325, \"_stat_site_order\": 324}, {\"site\": 326, \"_stat_site_order\": 325}, {\"site\": 327, \"_stat_site_order\": 326}, {\"site\": 328, \"_stat_site_order\": 327}, {\"site\": 329, \"_stat_site_order\": 328}, {\"site\": 330, \"_stat_site_order\": 329}, {\"site\": 331, \"_stat_site_order\": 330}, {\"site\": 332, \"_stat_site_order\": 331}, {\"site\": 333, \"_stat_site_order\": 332}, {\"site\": 334, \"_stat_site_order\": 333}, {\"site\": 335, \"_stat_site_order\": 334}, {\"site\": 336, \"_stat_site_order\": 335}, {\"site\": 337, \"_stat_site_order\": 336}, {\"site\": 338, \"_stat_site_order\": 337}, {\"site\": 339, \"_stat_site_order\": 338}, {\"site\": 340, \"_stat_site_order\": 339}, {\"site\": 341, \"_stat_site_order\": 340}, {\"site\": 342, \"_stat_site_order\": 341}, {\"site\": 343, \"_stat_site_order\": 342}, {\"site\": 345, \"_stat_site_order\": 343}, {\"site\": 346, \"_stat_site_order\": 344}, {\"site\": 347, \"_stat_site_order\": 345}, {\"site\": 348, \"_stat_site_order\": 346}, {\"site\": 349, \"_stat_site_order\": 347}, {\"site\": 350, \"_stat_site_order\": 348}, {\"site\": 351, \"_stat_site_order\": 349}, {\"site\": 352, \"_stat_site_order\": 350}, {\"site\": 353, \"_stat_site_order\": 351}, {\"site\": 354, \"_stat_site_order\": 352}, {\"site\": 355, \"_stat_site_order\": 353}, {\"site\": 356, \"_stat_site_order\": 354}, {\"site\": 357, \"_stat_site_order\": 355}, {\"site\": 358, \"_stat_site_order\": 356}, {\"site\": 359, \"_stat_site_order\": 357}, {\"site\": 360, \"_stat_site_order\": 358}, {\"site\": 361, \"_stat_site_order\": 359}, {\"site\": 362, \"_stat_site_order\": 360}, {\"site\": 363, \"_stat_site_order\": 361}, {\"site\": 364, \"_stat_site_order\": 362}, {\"site\": 365, \"_stat_site_order\": 363}, {\"site\": 366, \"_stat_site_order\": 364}, {\"site\": 367, \"_stat_site_order\": 365}, {\"site\": 368, \"_stat_site_order\": 366}, {\"site\": 369, \"_stat_site_order\": 367}, {\"site\": 370, \"_stat_site_order\": 368}, {\"site\": 371, \"_stat_site_order\": 369}, {\"site\": 372, \"_stat_site_order\": 370}, {\"site\": 373, \"_stat_site_order\": 371}, {\"site\": 374, \"_stat_site_order\": 372}, {\"site\": 375, \"_stat_site_order\": 373}, {\"site\": 376, \"_stat_site_order\": 374}, {\"site\": 377, \"_stat_site_order\": 375}, {\"site\": 378, \"_stat_site_order\": 376}, {\"site\": 379, \"_stat_site_order\": 377}, {\"site\": 380, \"_stat_site_order\": 378}, {\"site\": 381, \"_stat_site_order\": 379}, {\"site\": 382, \"_stat_site_order\": 380}, {\"site\": 383, \"_stat_site_order\": 381}, {\"site\": 384, \"_stat_site_order\": 382}, {\"site\": 385, \"_stat_site_order\": 383}, {\"site\": 386, \"_stat_site_order\": 384}, {\"site\": 387, \"_stat_site_order\": 385}, {\"site\": 388, \"_stat_site_order\": 386}, {\"site\": 389, \"_stat_site_order\": 387}, {\"site\": 390, \"_stat_site_order\": 388}, {\"site\": 391, \"_stat_site_order\": 389}, {\"site\": 392, \"_stat_site_order\": 390}, {\"site\": 393, \"_stat_site_order\": 391}, {\"site\": 394, \"_stat_site_order\": 392}, {\"site\": 395, \"_stat_site_order\": 393}, {\"site\": 396, \"_stat_site_order\": 394}, {\"site\": 397, \"_stat_site_order\": 395}, {\"site\": 398, \"_stat_site_order\": 396}, {\"site\": 399, \"_stat_site_order\": 397}, {\"site\": 400, \"_stat_site_order\": 398}, {\"site\": 401, \"_stat_site_order\": 399}, {\"site\": 402, \"_stat_site_order\": 400}, {\"site\": 403, \"_stat_site_order\": 401}, {\"site\": 404, \"_stat_site_order\": 402}, {\"site\": 405, \"_stat_site_order\": 403}, {\"site\": 406, \"_stat_site_order\": 404}, {\"site\": 407, \"_stat_site_order\": 405}, {\"site\": 408, \"_stat_site_order\": 406}, {\"site\": 409, \"_stat_site_order\": 407}, {\"site\": 410, \"_stat_site_order\": 408}, {\"site\": 411, \"_stat_site_order\": 409}, {\"site\": 412, \"_stat_site_order\": 410}, {\"site\": 413, \"_stat_site_order\": 411}, {\"site\": 414, \"_stat_site_order\": 412}, {\"site\": 415, \"_stat_site_order\": 413}, {\"site\": 416, \"_stat_site_order\": 414}, {\"site\": 417, \"_stat_site_order\": 415}, {\"site\": 418, \"_stat_site_order\": 416}, {\"site\": 419, \"_stat_site_order\": 417}, {\"site\": 420, \"_stat_site_order\": 418}, {\"site\": 421, \"_stat_site_order\": 419}, {\"site\": 422, \"_stat_site_order\": 420}, {\"site\": 423, \"_stat_site_order\": 421}, {\"site\": 424, \"_stat_site_order\": 422}, {\"site\": 425, \"_stat_site_order\": 423}, {\"site\": 426, \"_stat_site_order\": 424}, {\"site\": 427, \"_stat_site_order\": 425}, {\"site\": 428, \"_stat_site_order\": 426}, {\"site\": 429, \"_stat_site_order\": 427}, {\"site\": 430, \"_stat_site_order\": 428}, {\"site\": 431, \"_stat_site_order\": 429}, {\"site\": 432, \"_stat_site_order\": 430}, {\"site\": 433, \"_stat_site_order\": 431}, {\"site\": 434, \"_stat_site_order\": 432}, {\"site\": 435, \"_stat_site_order\": 433}, {\"site\": 436, \"_stat_site_order\": 434}, {\"site\": 437, \"_stat_site_order\": 435}, {\"site\": 438, \"_stat_site_order\": 436}, {\"site\": 439, \"_stat_site_order\": 437}, {\"site\": 440, \"_stat_site_order\": 438}, {\"site\": 441, \"_stat_site_order\": 439}, {\"site\": 442, \"_stat_site_order\": 440}, {\"site\": 443, \"_stat_site_order\": 441}, {\"site\": 444, \"_stat_site_order\": 442}, {\"site\": 445, \"_stat_site_order\": 443}, {\"site\": 446, \"_stat_site_order\": 444}, {\"site\": 447, \"_stat_site_order\": 445}, {\"site\": 448, \"_stat_site_order\": 446}, {\"site\": 449, \"_stat_site_order\": 447}, {\"site\": 450, \"_stat_site_order\": 448}, {\"site\": 451, \"_stat_site_order\": 449}, {\"site\": 452, \"_stat_site_order\": 450}, {\"site\": 453, \"_stat_site_order\": 451}, {\"site\": 454, \"_stat_site_order\": 452}, {\"site\": 455, \"_stat_site_order\": 453}, {\"site\": 456, \"_stat_site_order\": 454}, {\"site\": 457, \"_stat_site_order\": 455}, {\"site\": 458, \"_stat_site_order\": 456}, {\"site\": 459, \"_stat_site_order\": 457}, {\"site\": 460, \"_stat_site_order\": 458}, {\"site\": 461, \"_stat_site_order\": 459}, {\"site\": 462, \"_stat_site_order\": 460}, {\"site\": 463, \"_stat_site_order\": 461}, {\"site\": 464, \"_stat_site_order\": 462}, {\"site\": 465, \"_stat_site_order\": 463}, {\"site\": 466, \"_stat_site_order\": 464}, {\"site\": 467, \"_stat_site_order\": 465}, {\"site\": 468, \"_stat_site_order\": 466}, {\"site\": 469, \"_stat_site_order\": 467}, {\"site\": 470, \"_stat_site_order\": 468}, {\"site\": 471, \"_stat_site_order\": 469}, {\"site\": 472, \"_stat_site_order\": 470}, {\"site\": 473, \"_stat_site_order\": 471}, {\"site\": 474, \"_stat_site_order\": 472}, {\"site\": 475, \"_stat_site_order\": 473}, {\"site\": 476, \"_stat_site_order\": 474}, {\"site\": 477, \"_stat_site_order\": 475}, {\"site\": 478, \"_stat_site_order\": 476}, {\"site\": 479, \"_stat_site_order\": 477}, {\"site\": 480, \"_stat_site_order\": 478}, {\"site\": 481, \"_stat_site_order\": 479}, {\"site\": 482, \"_stat_site_order\": 480}, {\"site\": 483, \"_stat_site_order\": 481}, {\"site\": 484, \"_stat_site_order\": 482}, {\"site\": 485, \"_stat_site_order\": 483}, {\"site\": 486, \"_stat_site_order\": 484}, {\"site\": 487, \"_stat_site_order\": 485}, {\"site\": 488, \"_stat_site_order\": 486}, {\"site\": 489, \"_stat_site_order\": 487}, {\"site\": 490, \"_stat_site_order\": 488}, {\"site\": 491, \"_stat_site_order\": 489}, {\"site\": 492, \"_stat_site_order\": 490}, {\"site\": 493, \"_stat_site_order\": 491}, {\"site\": 494, \"_stat_site_order\": 492}, {\"site\": 495, \"_stat_site_order\": 493}, {\"site\": 496, \"_stat_site_order\": 494}, {\"site\": 497, \"_stat_site_order\": 495}, {\"site\": 498, \"_stat_site_order\": 496}, {\"site\": 499, \"_stat_site_order\": 497}, {\"site\": 500, \"_stat_site_order\": 498}, {\"site\": 501, \"_stat_site_order\": 499}, {\"site\": 502, \"_stat_site_order\": 500}, {\"site\": 503, \"_stat_site_order\": 501}, {\"site\": 504, \"_stat_site_order\": 502}, {\"site\": 505, \"_stat_site_order\": 503}, {\"site\": 506, \"_stat_site_order\": 504}, {\"site\": 507, \"_stat_site_order\": 505}, {\"site\": 508, \"_stat_site_order\": 506}, {\"site\": 509, \"_stat_site_order\": 507}, {\"site\": 510, \"_stat_site_order\": 508}, {\"site\": 511, \"_stat_site_order\": 509}, {\"site\": 512, \"_stat_site_order\": 510}, {\"site\": 513, \"_stat_site_order\": 511}, {\"site\": 514, \"_stat_site_order\": 512}, {\"site\": 515, \"_stat_site_order\": 513}, {\"site\": 516, \"_stat_site_order\": 514}, {\"site\": 517, \"_stat_site_order\": 515}, {\"site\": 518, \"_stat_site_order\": 516}, {\"site\": 519, \"_stat_site_order\": 517}, {\"site\": 520, \"_stat_site_order\": 518}, {\"site\": 521, \"_stat_site_order\": 519}, {\"site\": 522, \"_stat_site_order\": 520}, {\"site\": 523, \"_stat_site_order\": 521}, {\"site\": 524, \"_stat_site_order\": 522}, {\"site\": 525, \"_stat_site_order\": 523}, {\"site\": 526, \"_stat_site_order\": 524}, {\"site\": 527, \"_stat_site_order\": 525}, {\"site\": 528, \"_stat_site_order\": 526}, {\"site\": 529, \"_stat_site_order\": 527}, {\"site\": 530, \"_stat_site_order\": 528}, {\"site\": 531, \"_stat_site_order\": 529}, {\"site\": 532, \"_stat_site_order\": 530}, {\"site\": 533, \"_stat_site_order\": 531}, {\"site\": 534, \"_stat_site_order\": 532}, {\"site\": 535, \"_stat_site_order\": 533}, {\"site\": 536, \"_stat_site_order\": 534}, {\"site\": 537, \"_stat_site_order\": 535}, {\"site\": 538, \"_stat_site_order\": 536}, {\"site\": 539, \"_stat_site_order\": 537}, {\"site\": 540, \"_stat_site_order\": 538}, {\"site\": 541, \"_stat_site_order\": 539}, {\"site\": 542, \"_stat_site_order\": 540}, {\"site\": 543, \"_stat_site_order\": 541}, {\"site\": 544, \"_stat_site_order\": 542}, {\"site\": 545, \"_stat_site_order\": 543}, {\"site\": 546, \"_stat_site_order\": 544}, {\"site\": 547, \"_stat_site_order\": 545}, {\"site\": 548, \"_stat_site_order\": 546}, {\"site\": 549, \"_stat_site_order\": 547}, {\"site\": 550, \"_stat_site_order\": 548}, {\"site\": 551, \"_stat_site_order\": 549}, {\"site\": 552, \"_stat_site_order\": 550}, {\"site\": 553, \"_stat_site_order\": 551}, {\"site\": 554, \"_stat_site_order\": 552}, {\"site\": 555, \"_stat_site_order\": 553}, {\"site\": 556, \"_stat_site_order\": 554}, {\"site\": 557, \"_stat_site_order\": 555}, {\"site\": 558, \"_stat_site_order\": 556}, {\"site\": 559, \"_stat_site_order\": 557}, {\"site\": 560, \"_stat_site_order\": 558}, {\"site\": 561, \"_stat_site_order\": 559}, {\"site\": 562, \"_stat_site_order\": 560}, {\"site\": 563, \"_stat_site_order\": 561}, {\"site\": 564, \"_stat_site_order\": 562}, {\"site\": 565, \"_stat_site_order\": 563}, {\"site\": 566, \"_stat_site_order\": 564}, {\"site\": 567, \"_stat_site_order\": 565}, {\"site\": 568, \"_stat_site_order\": 566}, {\"site\": 569, \"_stat_site_order\": 567}, {\"site\": 570, \"_stat_site_order\": 568}, {\"site\": 571, \"_stat_site_order\": 569}, {\"site\": 572, \"_stat_site_order\": 570}, {\"site\": 573, \"_stat_site_order\": 571}, {\"site\": 574, \"_stat_site_order\": 572}, {\"site\": 575, \"_stat_site_order\": 573}, {\"site\": 576, \"_stat_site_order\": 574}, {\"site\": 577, \"_stat_site_order\": 575}, {\"site\": 578, \"_stat_site_order\": 576}, {\"site\": 579, \"_stat_site_order\": 577}, {\"site\": 580, \"_stat_site_order\": 578}, {\"site\": 581, \"_stat_site_order\": 579}, {\"site\": 582, \"_stat_site_order\": 580}, {\"site\": 583, \"_stat_site_order\": 581}, {\"site\": 584, \"_stat_site_order\": 582}, {\"site\": 585, \"_stat_site_order\": 583}, {\"site\": 586, \"_stat_site_order\": 584}, {\"site\": 587, \"_stat_site_order\": 585}, {\"site\": 588, \"_stat_site_order\": 586}, {\"site\": 589, \"_stat_site_order\": 587}, {\"site\": 590, \"_stat_site_order\": 588}, {\"site\": 591, \"_stat_site_order\": 589}, {\"site\": 592, \"_stat_site_order\": 590}, {\"site\": 593, \"_stat_site_order\": 591}, {\"site\": 594, \"_stat_site_order\": 592}, {\"site\": 595, \"_stat_site_order\": 593}, {\"site\": 596, \"_stat_site_order\": 594}, {\"site\": 597, \"_stat_site_order\": 595}, {\"site\": 598, \"_stat_site_order\": 596}, {\"site\": 599, \"_stat_site_order\": 597}, {\"site\": 600, \"_stat_site_order\": 598}, {\"site\": 601, \"_stat_site_order\": 599}, {\"site\": 602, \"_stat_site_order\": 600}, {\"site\": 603, \"_stat_site_order\": 601}, {\"site\": 604, \"_stat_site_order\": 602}, {\"site\": 605, \"_stat_site_order\": 603}, {\"site\": 606, \"_stat_site_order\": 604}, {\"site\": 607, \"_stat_site_order\": 605}, {\"site\": 608, \"_stat_site_order\": 606}, {\"site\": 609, \"_stat_site_order\": 607}, {\"site\": 610, \"_stat_site_order\": 608}, {\"site\": 611, \"_stat_site_order\": 609}, {\"site\": 612, \"_stat_site_order\": 610}, {\"site\": 613, \"_stat_site_order\": 611}, {\"site\": 614, \"_stat_site_order\": 612}, {\"site\": 615, \"_stat_site_order\": 613}, {\"site\": 616, \"_stat_site_order\": 614}, {\"site\": 617, \"_stat_site_order\": 615}, {\"site\": 618, \"_stat_site_order\": 616}, {\"site\": 619, \"_stat_site_order\": 617}, {\"site\": 620, \"_stat_site_order\": 618}, {\"site\": 621, \"_stat_site_order\": 619}, {\"site\": 622, \"_stat_site_order\": 620}, {\"site\": 623, \"_stat_site_order\": 621}, {\"site\": 624, \"_stat_site_order\": 622}, {\"site\": 625, \"_stat_site_order\": 623}, {\"site\": 626, \"_stat_site_order\": 624}, {\"site\": 627, \"_stat_site_order\": 625}, {\"site\": 628, \"_stat_site_order\": 626}, {\"site\": 629, \"_stat_site_order\": 627}, {\"site\": 630, \"_stat_site_order\": 628}, {\"site\": 631, \"_stat_site_order\": 629}, {\"site\": 632, \"_stat_site_order\": 630}, {\"site\": 633, \"_stat_site_order\": 631}, {\"site\": 634, \"_stat_site_order\": 632}, {\"site\": 635, \"_stat_site_order\": 633}, {\"site\": 636, \"_stat_site_order\": 634}, {\"site\": 637, \"_stat_site_order\": 635}, {\"site\": 638, \"_stat_site_order\": 636}, {\"site\": 639, \"_stat_site_order\": 637}, {\"site\": 640, \"_stat_site_order\": 638}, {\"site\": 641, \"_stat_site_order\": 639}, {\"site\": 642, \"_stat_site_order\": 640}, {\"site\": 643, \"_stat_site_order\": 641}, {\"site\": 644, \"_stat_site_order\": 642}, {\"site\": 645, \"_stat_site_order\": 643}, {\"site\": 646, \"_stat_site_order\": 644}, {\"site\": 647, \"_stat_site_order\": 645}, {\"site\": 648, \"_stat_site_order\": 646}, {\"site\": 649, \"_stat_site_order\": 647}, {\"site\": 650, \"_stat_site_order\": 648}, {\"site\": 651, \"_stat_site_order\": 649}, {\"site\": 652, \"_stat_site_order\": 650}, {\"site\": 653, \"_stat_site_order\": 651}, {\"site\": 654, \"_stat_site_order\": 652}, {\"site\": 655, \"_stat_site_order\": 653}, {\"site\": 656, \"_stat_site_order\": 654}, {\"site\": 657, \"_stat_site_order\": 655}, {\"site\": 658, \"_stat_site_order\": 656}, {\"site\": 659, \"_stat_site_order\": 657}, {\"site\": 660, \"_stat_site_order\": 658}, {\"site\": 661, \"_stat_site_order\": 659}, {\"site\": 662, \"_stat_site_order\": 660}, {\"site\": 663, \"_stat_site_order\": 661}, {\"site\": 664, \"_stat_site_order\": 662}, {\"site\": 665, \"_stat_site_order\": 663}, {\"site\": 666, \"_stat_site_order\": 664}, {\"site\": 667, \"_stat_site_order\": 665}, {\"site\": 668, \"_stat_site_order\": 666}, {\"site\": 669, \"_stat_site_order\": 667}, {\"site\": 670, \"_stat_site_order\": 668}, {\"site\": 671, \"_stat_site_order\": 669}, {\"site\": 672, \"_stat_site_order\": 670}, {\"site\": 673, \"_stat_site_order\": 671}, {\"site\": 674, \"_stat_site_order\": 672}, {\"site\": 675, \"_stat_site_order\": 673}, {\"site\": 676, \"_stat_site_order\": 674}, {\"site\": 677, \"_stat_site_order\": 675}, {\"site\": 678, \"_stat_site_order\": 676}, {\"site\": 679, \"_stat_site_order\": 677}, {\"site\": 680, \"_stat_site_order\": 678}, {\"site\": 681, \"_stat_site_order\": 679}, {\"site\": 682, \"_stat_site_order\": 680}, {\"site\": 683, \"_stat_site_order\": 681}, {\"site\": 684, \"_stat_site_order\": 682}, {\"site\": 685, \"_stat_site_order\": 683}, {\"site\": 686, \"_stat_site_order\": 684}, {\"site\": 687, \"_stat_site_order\": 685}, {\"site\": 688, \"_stat_site_order\": 686}, {\"site\": 689, \"_stat_site_order\": 687}, {\"site\": 690, \"_stat_site_order\": 688}, {\"site\": 691, \"_stat_site_order\": 689}, {\"site\": 693, \"_stat_site_order\": 690}, {\"site\": 694, \"_stat_site_order\": 691}, {\"site\": 695, \"_stat_site_order\": 692}, {\"site\": 696, \"_stat_site_order\": 693}, {\"site\": 697, \"_stat_site_order\": 694}, {\"site\": 698, \"_stat_site_order\": 695}, {\"site\": 699, \"_stat_site_order\": 696}, {\"site\": 700, \"_stat_site_order\": 697}, {\"site\": 701, \"_stat_site_order\": 698}, {\"site\": 702, \"_stat_site_order\": 699}, {\"site\": 703, \"_stat_site_order\": 700}, {\"site\": 704, \"_stat_site_order\": 701}, {\"site\": 705, \"_stat_site_order\": 702}, {\"site\": 706, \"_stat_site_order\": 703}, {\"site\": 707, \"_stat_site_order\": 704}, {\"site\": 708, \"_stat_site_order\": 705}, {\"site\": 709, \"_stat_site_order\": 706}, {\"site\": 710, \"_stat_site_order\": 707}, {\"site\": 711, \"_stat_site_order\": 708}, {\"site\": 712, \"_stat_site_order\": 709}, {\"site\": 713, \"_stat_site_order\": 710}, {\"site\": 714, \"_stat_site_order\": 711}, {\"site\": 715, \"_stat_site_order\": 712}, {\"site\": 716, \"_stat_site_order\": 713}, {\"site\": 717, \"_stat_site_order\": 714}, {\"site\": 718, \"_stat_site_order\": 715}, {\"site\": 719, \"_stat_site_order\": 716}, {\"site\": 720, \"_stat_site_order\": 717}, {\"site\": 721, \"_stat_site_order\": 718}, {\"site\": 722, \"_stat_site_order\": 719}, {\"site\": 723, \"_stat_site_order\": 720}, {\"site\": 724, \"_stat_site_order\": 721}, {\"site\": 725, \"_stat_site_order\": 722}, {\"site\": 726, \"_stat_site_order\": 723}, {\"site\": 727, \"_stat_site_order\": 724}, {\"site\": 728, \"_stat_site_order\": 725}, {\"site\": 729, \"_stat_site_order\": 726}, {\"site\": 730, \"_stat_site_order\": 727}, {\"site\": 731, \"_stat_site_order\": 728}, {\"site\": 732, \"_stat_site_order\": 729}, {\"site\": 733, \"_stat_site_order\": 730}, {\"site\": 734, \"_stat_site_order\": 731}, {\"site\": 735, \"_stat_site_order\": 732}, {\"site\": 736, \"_stat_site_order\": 733}, {\"site\": 737, \"_stat_site_order\": 734}, {\"site\": 738, \"_stat_site_order\": 735}, {\"site\": 739, \"_stat_site_order\": 736}, {\"site\": 740, \"_stat_site_order\": 737}, {\"site\": 741, \"_stat_site_order\": 738}, {\"site\": 742, \"_stat_site_order\": 739}, {\"site\": 743, \"_stat_site_order\": 740}, {\"site\": 744, \"_stat_site_order\": 741}, {\"site\": 745, \"_stat_site_order\": 742}, {\"site\": 746, \"_stat_site_order\": 743}, {\"site\": 747, \"_stat_site_order\": 744}, {\"site\": 748, \"_stat_site_order\": 745}, {\"site\": 749, \"_stat_site_order\": 746}, {\"site\": 750, \"_stat_site_order\": 747}, {\"site\": 751, \"_stat_site_order\": 748}, {\"site\": 752, \"_stat_site_order\": 749}, {\"site\": 753, \"_stat_site_order\": 750}, {\"site\": 754, \"_stat_site_order\": 751}, {\"site\": 755, \"_stat_site_order\": 752}, {\"site\": 756, \"_stat_site_order\": 753}, {\"site\": 757, \"_stat_site_order\": 754}, {\"site\": 758, \"_stat_site_order\": 755}, {\"site\": 759, \"_stat_site_order\": 756}, {\"site\": 760, \"_stat_site_order\": 757}, {\"site\": 761, \"_stat_site_order\": 758}, {\"site\": 762, \"_stat_site_order\": 759}, {\"site\": 763, \"_stat_site_order\": 760}, {\"site\": 764, \"_stat_site_order\": 761}, {\"site\": 765, \"_stat_site_order\": 762}, {\"site\": 766, \"_stat_site_order\": 763}, {\"site\": 767, \"_stat_site_order\": 764}, {\"site\": 768, \"_stat_site_order\": 765}, {\"site\": 769, \"_stat_site_order\": 766}, {\"site\": 770, \"_stat_site_order\": 767}, {\"site\": 771, \"_stat_site_order\": 768}, {\"site\": 772, \"_stat_site_order\": 769}, {\"site\": 773, \"_stat_site_order\": 770}, {\"site\": 774, \"_stat_site_order\": 771}, {\"site\": 775, \"_stat_site_order\": 772}, {\"site\": 776, \"_stat_site_order\": 773}, {\"site\": 777, \"_stat_site_order\": 774}, {\"site\": 778, \"_stat_site_order\": 775}, {\"site\": 779, \"_stat_site_order\": 776}, {\"site\": 780, \"_stat_site_order\": 777}, {\"site\": 781, \"_stat_site_order\": 778}, {\"site\": 782, \"_stat_site_order\": 779}, {\"site\": 783, \"_stat_site_order\": 780}, {\"site\": 784, \"_stat_site_order\": 781}, {\"site\": 785, \"_stat_site_order\": 782}, {\"site\": 786, \"_stat_site_order\": 783}, {\"site\": 787, \"_stat_site_order\": 784}, {\"site\": 788, \"_stat_site_order\": 785}, {\"site\": 789, \"_stat_site_order\": 786}, {\"site\": 790, \"_stat_site_order\": 787}, {\"site\": 791, \"_stat_site_order\": 788}, {\"site\": 792, \"_stat_site_order\": 789}, {\"site\": 793, \"_stat_site_order\": 790}, {\"site\": 794, \"_stat_site_order\": 791}, {\"site\": 795, \"_stat_site_order\": 792}, {\"site\": 796, \"_stat_site_order\": 793}, {\"site\": 797, \"_stat_site_order\": 794}, {\"site\": 798, \"_stat_site_order\": 795}, {\"site\": 799, \"_stat_site_order\": 796}, {\"site\": 800, \"_stat_site_order\": 797}, {\"site\": 801, \"_stat_site_order\": 798}, {\"site\": 802, \"_stat_site_order\": 799}, {\"site\": 803, \"_stat_site_order\": 800}, {\"site\": 804, \"_stat_site_order\": 801}, {\"site\": 805, \"_stat_site_order\": 802}, {\"site\": 806, \"_stat_site_order\": 803}, {\"site\": 807, \"_stat_site_order\": 804}, {\"site\": 808, \"_stat_site_order\": 805}, {\"site\": 809, \"_stat_site_order\": 806}, {\"site\": 810, \"_stat_site_order\": 807}, {\"site\": 811, \"_stat_site_order\": 808}, {\"site\": 812, \"_stat_site_order\": 809}, {\"site\": 813, \"_stat_site_order\": 810}, {\"site\": 814, \"_stat_site_order\": 811}, {\"site\": 815, \"_stat_site_order\": 812}, {\"site\": 816, \"_stat_site_order\": 813}, {\"site\": 817, \"_stat_site_order\": 814}, {\"site\": 818, \"_stat_site_order\": 815}, {\"site\": 819, \"_stat_site_order\": 816}, {\"site\": 820, \"_stat_site_order\": 817}, {\"site\": 821, \"_stat_site_order\": 818}, {\"site\": 822, \"_stat_site_order\": 819}, {\"site\": 823, \"_stat_site_order\": 820}, {\"site\": 824, \"_stat_site_order\": 821}, {\"site\": 825, \"_stat_site_order\": 822}, {\"site\": 826, \"_stat_site_order\": 823}, {\"site\": 827, \"_stat_site_order\": 824}, {\"site\": 828, \"_stat_site_order\": 825}, {\"site\": 829, \"_stat_site_order\": 826}, {\"site\": 830, \"_stat_site_order\": 827}, {\"site\": 831, \"_stat_site_order\": 828}, {\"site\": 832, \"_stat_site_order\": 829}, {\"site\": 833, \"_stat_site_order\": 830}, {\"site\": 834, \"_stat_site_order\": 831}, {\"site\": 835, \"_stat_site_order\": 832}, {\"site\": 836, \"_stat_site_order\": 833}, {\"site\": 837, \"_stat_site_order\": 834}, {\"site\": 838, \"_stat_site_order\": 835}, {\"site\": 839, \"_stat_site_order\": 836}, {\"site\": 840, \"_stat_site_order\": 837}, {\"site\": 841, \"_stat_site_order\": 838}, {\"site\": 842, \"_stat_site_order\": 839}, {\"site\": 843, \"_stat_site_order\": 840}, {\"site\": 844, \"_stat_site_order\": 841}, {\"site\": 845, \"_stat_site_order\": 842}, {\"site\": 846, \"_stat_site_order\": 843}, {\"site\": 847, \"_stat_site_order\": 844}, {\"site\": 848, \"_stat_site_order\": 845}, {\"site\": 849, \"_stat_site_order\": 846}, {\"site\": 850, \"_stat_site_order\": 847}, {\"site\": 851, \"_stat_site_order\": 848}, {\"site\": 852, \"_stat_site_order\": 849}, {\"site\": 853, \"_stat_site_order\": 850}, {\"site\": 854, \"_stat_site_order\": 851}, {\"site\": 855, \"_stat_site_order\": 852}, {\"site\": 856, \"_stat_site_order\": 853}, {\"site\": 857, \"_stat_site_order\": 854}, {\"site\": 858, \"_stat_site_order\": 855}, {\"site\": 859, \"_stat_site_order\": 856}, {\"site\": 860, \"_stat_site_order\": 857}, {\"site\": 861, \"_stat_site_order\": 858}, {\"site\": 862, \"_stat_site_order\": 859}, {\"site\": 863, \"_stat_site_order\": 860}, {\"site\": 864, \"_stat_site_order\": 861}, {\"site\": 865, \"_stat_site_order\": 862}, {\"site\": 866, \"_stat_site_order\": 863}, {\"site\": 867, \"_stat_site_order\": 864}, {\"site\": 868, \"_stat_site_order\": 865}, {\"site\": 869, \"_stat_site_order\": 866}, {\"site\": 870, \"_stat_site_order\": 867}, {\"site\": 871, \"_stat_site_order\": 868}, {\"site\": 872, \"_stat_site_order\": 869}, {\"site\": 873, \"_stat_site_order\": 870}, {\"site\": 874, \"_stat_site_order\": 871}, {\"site\": 875, \"_stat_site_order\": 872}, {\"site\": 876, \"_stat_site_order\": 873}, {\"site\": 877, \"_stat_site_order\": 874}, {\"site\": 878, \"_stat_site_order\": 875}, {\"site\": 879, \"_stat_site_order\": 876}, {\"site\": 880, \"_stat_site_order\": 877}, {\"site\": 881, \"_stat_site_order\": 878}, {\"site\": 882, \"_stat_site_order\": 879}, {\"site\": 883, \"_stat_site_order\": 880}, {\"site\": 884, \"_stat_site_order\": 881}, {\"site\": 885, \"_stat_site_order\": 882}, {\"site\": 886, \"_stat_site_order\": 883}, {\"site\": 887, \"_stat_site_order\": 884}, {\"site\": 888, \"_stat_site_order\": 885}, {\"site\": 889, \"_stat_site_order\": 886}, {\"site\": 890, \"_stat_site_order\": 887}, {\"site\": 891, \"_stat_site_order\": 888}, {\"site\": 892, \"_stat_site_order\": 889}, {\"site\": 893, \"_stat_site_order\": 890}, {\"site\": 894, \"_stat_site_order\": 891}, {\"site\": 895, \"_stat_site_order\": 892}, {\"site\": 896, \"_stat_site_order\": 893}, {\"site\": 897, \"_stat_site_order\": 894}, {\"site\": 898, \"_stat_site_order\": 895}, {\"site\": 899, \"_stat_site_order\": 896}, {\"site\": 900, \"_stat_site_order\": 897}, {\"site\": 901, \"_stat_site_order\": 898}, {\"site\": 902, \"_stat_site_order\": 899}, {\"site\": 903, \"_stat_site_order\": 900}, {\"site\": 904, \"_stat_site_order\": 901}, {\"site\": 905, \"_stat_site_order\": 902}, {\"site\": 906, \"_stat_site_order\": 903}, {\"site\": 907, \"_stat_site_order\": 904}, {\"site\": 908, \"_stat_site_order\": 905}, {\"site\": 909, \"_stat_site_order\": 906}, {\"site\": 910, \"_stat_site_order\": 907}, {\"site\": 911, \"_stat_site_order\": 908}, {\"site\": 912, \"_stat_site_order\": 909}, {\"site\": 913, \"_stat_site_order\": 910}, {\"site\": 914, \"_stat_site_order\": 911}, {\"site\": 915, \"_stat_site_order\": 912}, {\"site\": 916, \"_stat_site_order\": 913}, {\"site\": 917, \"_stat_site_order\": 914}, {\"site\": 918, \"_stat_site_order\": 915}, {\"site\": 919, \"_stat_site_order\": 916}, {\"site\": 920, \"_stat_site_order\": 917}, {\"site\": 921, \"_stat_site_order\": 918}, {\"site\": 922, \"_stat_site_order\": 919}, {\"site\": 923, \"_stat_site_order\": 920}, {\"site\": 924, \"_stat_site_order\": 921}, {\"site\": 925, \"_stat_site_order\": 922}, {\"site\": 926, \"_stat_site_order\": 923}, {\"site\": 927, \"_stat_site_order\": 924}, {\"site\": 928, \"_stat_site_order\": 925}, {\"site\": 929, \"_stat_site_order\": 926}, {\"site\": 930, \"_stat_site_order\": 927}, {\"site\": 931, \"_stat_site_order\": 928}, {\"site\": 932, \"_stat_site_order\": 929}, {\"site\": 933, \"_stat_site_order\": 930}, {\"site\": 934, \"_stat_site_order\": 931}, {\"site\": 935, \"_stat_site_order\": 932}, {\"site\": 936, \"_stat_site_order\": 933}, {\"site\": 937, \"_stat_site_order\": 934}, {\"site\": 938, \"_stat_site_order\": 935}, {\"site\": 939, \"_stat_site_order\": 936}, {\"site\": 940, \"_stat_site_order\": 937}, {\"site\": 941, \"_stat_site_order\": 938}, {\"site\": 942, \"_stat_site_order\": 939}, {\"site\": 943, \"_stat_site_order\": 940}, {\"site\": 944, \"_stat_site_order\": 941}, {\"site\": 945, \"_stat_site_order\": 942}, {\"site\": 946, \"_stat_site_order\": 943}, {\"site\": 947, \"_stat_site_order\": 944}, {\"site\": 948, \"_stat_site_order\": 945}, {\"site\": 949, \"_stat_site_order\": 946}, {\"site\": 950, \"_stat_site_order\": 947}, {\"site\": 951, \"_stat_site_order\": 948}, {\"site\": 952, \"_stat_site_order\": 949}, {\"site\": 953, \"_stat_site_order\": 950}, {\"site\": 954, \"_stat_site_order\": 951}, {\"site\": 955, \"_stat_site_order\": 952}, {\"site\": 956, \"_stat_site_order\": 953}, {\"site\": 957, \"_stat_site_order\": 954}, {\"site\": 958, \"_stat_site_order\": 955}, {\"site\": 959, \"_stat_site_order\": 956}, {\"site\": 960, \"_stat_site_order\": 957}, {\"site\": 961, \"_stat_site_order\": 958}, {\"site\": 962, \"_stat_site_order\": 959}, {\"site\": 963, \"_stat_site_order\": 960}, {\"site\": 964, \"_stat_site_order\": 961}, {\"site\": 965, \"_stat_site_order\": 962}, {\"site\": 966, \"_stat_site_order\": 963}, {\"site\": 967, \"_stat_site_order\": 964}, {\"site\": 968, \"_stat_site_order\": 965}, {\"site\": 969, \"_stat_site_order\": 966}, {\"site\": 970, \"_stat_site_order\": 967}, {\"site\": 971, \"_stat_site_order\": 968}, {\"site\": 972, \"_stat_site_order\": 969}, {\"site\": 973, \"_stat_site_order\": 970}, {\"site\": 974, \"_stat_site_order\": 971}, {\"site\": 975, \"_stat_site_order\": 972}, {\"site\": 976, \"_stat_site_order\": 973}, {\"site\": 977, \"_stat_site_order\": 974}, {\"site\": 978, \"_stat_site_order\": 975}, {\"site\": 979, \"_stat_site_order\": 976}, {\"site\": 980, \"_stat_site_order\": 977}, {\"site\": 981, \"_stat_site_order\": 978}, {\"site\": 982, \"_stat_site_order\": 979}, {\"site\": 983, \"_stat_site_order\": 980}, {\"site\": 984, \"_stat_site_order\": 981}, {\"site\": 985, \"_stat_site_order\": 982}, {\"site\": 986, \"_stat_site_order\": 983}, {\"site\": 987, \"_stat_site_order\": 984}, {\"site\": 988, \"_stat_site_order\": 985}, {\"site\": 989, \"_stat_site_order\": 986}, {\"site\": 990, \"_stat_site_order\": 987}, {\"site\": 991, \"_stat_site_order\": 988}, {\"site\": 992, \"_stat_site_order\": 989}, {\"site\": 993, \"_stat_site_order\": 990}, {\"site\": 994, \"_stat_site_order\": 991}, {\"site\": 995, \"_stat_site_order\": 992}, {\"site\": 996, \"_stat_site_order\": 993}, {\"site\": 997, \"_stat_site_order\": 994}, {\"site\": 998, \"_stat_site_order\": 995}, {\"site\": 999, \"_stat_site_order\": 996}, {\"site\": 1000, \"_stat_site_order\": 997}, {\"site\": 1001, \"_stat_site_order\": 998}, {\"site\": 1002, \"_stat_site_order\": 999}, {\"site\": 1003, \"_stat_site_order\": 1000}, {\"site\": 1004, \"_stat_site_order\": 1001}, {\"site\": 1005, \"_stat_site_order\": 1002}, {\"site\": 1006, \"_stat_site_order\": 1003}, {\"site\": 1007, \"_stat_site_order\": 1004}, {\"site\": 1008, \"_stat_site_order\": 1005}, {\"site\": 1009, \"_stat_site_order\": 1006}, {\"site\": 1010, \"_stat_site_order\": 1007}, {\"site\": 1011, \"_stat_site_order\": 1008}, {\"site\": 1012, \"_stat_site_order\": 1009}, {\"site\": 1013, \"_stat_site_order\": 1010}, {\"site\": 1014, \"_stat_site_order\": 1011}, {\"site\": 1015, \"_stat_site_order\": 1012}, {\"site\": 1016, \"_stat_site_order\": 1013}, {\"site\": 1017, \"_stat_site_order\": 1014}, {\"site\": 1018, \"_stat_site_order\": 1015}, {\"site\": 1019, \"_stat_site_order\": 1016}, {\"site\": 1020, \"_stat_site_order\": 1017}, {\"site\": 1021, \"_stat_site_order\": 1018}, {\"site\": 1022, \"_stat_site_order\": 1019}, {\"site\": 1023, \"_stat_site_order\": 1020}, {\"site\": 1024, \"_stat_site_order\": 1021}, {\"site\": 1025, \"_stat_site_order\": 1022}, {\"site\": 1026, \"_stat_site_order\": 1023}, {\"site\": 1027, \"_stat_site_order\": 1024}, {\"site\": 1028, \"_stat_site_order\": 1025}, {\"site\": 1029, \"_stat_site_order\": 1026}, {\"site\": 1030, \"_stat_site_order\": 1027}, {\"site\": 1031, \"_stat_site_order\": 1028}, {\"site\": 1032, \"_stat_site_order\": 1029}, {\"site\": 1033, \"_stat_site_order\": 1030}, {\"site\": 1034, \"_stat_site_order\": 1031}, {\"site\": 1035, \"_stat_site_order\": 1032}, {\"site\": 1036, \"_stat_site_order\": 1033}, {\"site\": 1037, \"_stat_site_order\": 1034}, {\"site\": 1038, \"_stat_site_order\": 1035}, {\"site\": 1039, \"_stat_site_order\": 1036}, {\"site\": 1040, \"_stat_site_order\": 1037}, {\"site\": 1041, \"_stat_site_order\": 1038}, {\"site\": 1042, \"_stat_site_order\": 1039}, {\"site\": 1043, \"_stat_site_order\": 1040}, {\"site\": 1044, \"_stat_site_order\": 1041}, {\"site\": 1045, \"_stat_site_order\": 1042}, {\"site\": 1046, \"_stat_site_order\": 1043}, {\"site\": 1047, \"_stat_site_order\": 1044}, {\"site\": 1048, \"_stat_site_order\": 1045}, {\"site\": 1049, \"_stat_site_order\": 1046}, {\"site\": 1051, \"_stat_site_order\": 1047}, {\"site\": 1052, \"_stat_site_order\": 1048}, {\"site\": 1053, \"_stat_site_order\": 1049}, {\"site\": 1054, \"_stat_site_order\": 1050}, {\"site\": 1055, \"_stat_site_order\": 1051}, {\"site\": 1056, \"_stat_site_order\": 1052}, {\"site\": 1057, \"_stat_site_order\": 1053}, {\"site\": 1058, \"_stat_site_order\": 1054}, {\"site\": 1059, \"_stat_site_order\": 1055}, {\"site\": 1060, \"_stat_site_order\": 1056}, {\"site\": 1061, \"_stat_site_order\": 1057}, {\"site\": 1062, \"_stat_site_order\": 1058}, {\"site\": 1063, \"_stat_site_order\": 1059}, {\"site\": 1064, \"_stat_site_order\": 1060}, {\"site\": 1065, \"_stat_site_order\": 1061}, {\"site\": 1066, \"_stat_site_order\": 1062}, {\"site\": 1067, \"_stat_site_order\": 1063}, {\"site\": 1068, \"_stat_site_order\": 1064}, {\"site\": 1069, \"_stat_site_order\": 1065}, {\"site\": 1070, \"_stat_site_order\": 1066}, {\"site\": 1071, \"_stat_site_order\": 1067}, {\"site\": 1072, \"_stat_site_order\": 1068}, {\"site\": 1073, \"_stat_site_order\": 1069}, {\"site\": 1074, \"_stat_site_order\": 1070}, {\"site\": 1075, \"_stat_site_order\": 1071}, {\"site\": 1076, \"_stat_site_order\": 1072}, {\"site\": 1077, \"_stat_site_order\": 1073}, {\"site\": 1078, \"_stat_site_order\": 1074}, {\"site\": 1079, \"_stat_site_order\": 1075}, {\"site\": 1080, \"_stat_site_order\": 1076}, {\"site\": 1081, \"_stat_site_order\": 1077}, {\"site\": 1082, \"_stat_site_order\": 1078}, {\"site\": 1083, \"_stat_site_order\": 1079}, {\"site\": 1084, \"_stat_site_order\": 1080}, {\"site\": 1085, \"_stat_site_order\": 1081}, {\"site\": 1086, \"_stat_site_order\": 1082}, {\"site\": 1087, \"_stat_site_order\": 1083}, {\"site\": 1088, \"_stat_site_order\": 1084}, {\"site\": 1089, \"_stat_site_order\": 1085}, {\"site\": 1090, \"_stat_site_order\": 1086}, {\"site\": 1091, \"_stat_site_order\": 1087}, {\"site\": 1092, \"_stat_site_order\": 1088}, {\"site\": 1093, \"_stat_site_order\": 1089}, {\"site\": 1094, \"_stat_site_order\": 1090}, {\"site\": 1095, \"_stat_site_order\": 1091}, {\"site\": 1096, \"_stat_site_order\": 1092}, {\"site\": 1097, \"_stat_site_order\": 1093}, {\"site\": 1098, \"_stat_site_order\": 1094}, {\"site\": 1099, \"_stat_site_order\": 1095}, {\"site\": 1100, \"_stat_site_order\": 1096}, {\"site\": 1101, \"_stat_site_order\": 1097}, {\"site\": 1102, \"_stat_site_order\": 1098}, {\"site\": 1103, \"_stat_site_order\": 1099}, {\"site\": 1104, \"_stat_site_order\": 1100}, {\"site\": 1105, \"_stat_site_order\": 1101}, {\"site\": 1106, \"_stat_site_order\": 1102}, {\"site\": 1107, \"_stat_site_order\": 1103}, {\"site\": 1108, \"_stat_site_order\": 1104}, {\"site\": 1109, \"_stat_site_order\": 1105}, {\"site\": 1110, \"_stat_site_order\": 1106}, {\"site\": 1111, \"_stat_site_order\": 1107}, {\"site\": 1112, \"_stat_site_order\": 1108}, {\"site\": 1113, \"_stat_site_order\": 1109}, {\"site\": 1114, \"_stat_site_order\": 1110}, {\"site\": 1115, \"_stat_site_order\": 1111}, {\"site\": 1116, \"_stat_site_order\": 1112}, {\"site\": 1117, \"_stat_site_order\": 1113}, {\"site\": 1118, \"_stat_site_order\": 1114}, {\"site\": 1119, \"_stat_site_order\": 1115}, {\"site\": 1120, \"_stat_site_order\": 1116}, {\"site\": 1121, \"_stat_site_order\": 1117}, {\"site\": 1122, \"_stat_site_order\": 1118}, {\"site\": 1123, \"_stat_site_order\": 1119}, {\"site\": 1124, \"_stat_site_order\": 1120}, {\"site\": 1125, \"_stat_site_order\": 1121}, {\"site\": 1126, \"_stat_site_order\": 1122}, {\"site\": 1127, \"_stat_site_order\": 1123}, {\"site\": 1128, \"_stat_site_order\": 1124}, {\"site\": 1129, \"_stat_site_order\": 1125}, {\"site\": 1130, \"_stat_site_order\": 1126}, {\"site\": 1131, \"_stat_site_order\": 1127}, {\"site\": 1132, \"_stat_site_order\": 1128}, {\"site\": 1133, \"_stat_site_order\": 1129}, {\"site\": 1134, \"_stat_site_order\": 1130}, {\"site\": 1135, \"_stat_site_order\": 1131}, {\"site\": 1136, \"_stat_site_order\": 1132}, {\"site\": 1137, \"_stat_site_order\": 1133}, {\"site\": 1138, \"_stat_site_order\": 1134}, {\"site\": 1139, \"_stat_site_order\": 1135}, {\"site\": 1140, \"_stat_site_order\": 1136}, {\"site\": 1141, \"_stat_site_order\": 1137}, {\"site\": 1142, \"_stat_site_order\": 1138}, {\"site\": 1143, \"_stat_site_order\": 1139}, {\"site\": 1144, \"_stat_site_order\": 1140}, {\"site\": 1145, \"_stat_site_order\": 1141}, {\"site\": 1146, \"_stat_site_order\": 1142}, {\"site\": 1147, \"_stat_site_order\": 1143}, {\"site\": 1148, \"_stat_site_order\": 1144}, {\"site\": 1149, \"_stat_site_order\": 1145}, {\"site\": 1150, \"_stat_site_order\": 1146}, {\"site\": 1151, \"_stat_site_order\": 1147}, {\"site\": 1152, \"_stat_site_order\": 1148}, {\"site\": 1153, \"_stat_site_order\": 1149}, {\"site\": 1154, \"_stat_site_order\": 1150}, {\"site\": 1155, \"_stat_site_order\": 1151}, {\"site\": 1156, \"_stat_site_order\": 1152}, {\"site\": 1157, \"_stat_site_order\": 1153}, {\"site\": 1158, \"_stat_site_order\": 1154}, {\"site\": 1159, \"_stat_site_order\": 1155}, {\"site\": 1160, \"_stat_site_order\": 1156}, {\"site\": 1161, \"_stat_site_order\": 1157}, {\"site\": 1162, \"_stat_site_order\": 1158}, {\"site\": 1163, \"_stat_site_order\": 1159}, {\"site\": 1164, \"_stat_site_order\": 1160}, {\"site\": 1165, \"_stat_site_order\": 1161}, {\"site\": 1166, \"_stat_site_order\": 1162}, {\"site\": 1167, \"_stat_site_order\": 1163}, {\"site\": 1168, \"_stat_site_order\": 1164}, {\"site\": 1169, \"_stat_site_order\": 1165}, {\"site\": 1170, \"_stat_site_order\": 1166}, {\"site\": 1171, \"_stat_site_order\": 1167}, {\"site\": 1172, \"_stat_site_order\": 1168}, {\"site\": 1173, \"_stat_site_order\": 1169}, {\"site\": 1174, \"_stat_site_order\": 1170}, {\"site\": 1175, \"_stat_site_order\": 1171}, {\"site\": 1176, \"_stat_site_order\": 1172}, {\"site\": 1177, \"_stat_site_order\": 1173}, {\"site\": 1178, \"_stat_site_order\": 1174}, {\"site\": 1179, \"_stat_site_order\": 1175}, {\"site\": 1180, \"_stat_site_order\": 1176}, {\"site\": 1181, \"_stat_site_order\": 1177}, {\"site\": 1182, \"_stat_site_order\": 1178}, {\"site\": 1183, \"_stat_site_order\": 1179}, {\"site\": 1184, \"_stat_site_order\": 1180}, {\"site\": 1185, \"_stat_site_order\": 1181}, {\"site\": 1186, \"_stat_site_order\": 1182}, {\"site\": 1187, \"_stat_site_order\": 1183}, {\"site\": 1188, \"_stat_site_order\": 1184}, {\"site\": 1189, \"_stat_site_order\": 1185}, {\"site\": 1190, \"_stat_site_order\": 1186}, {\"site\": 1191, \"_stat_site_order\": 1187}, {\"site\": 1192, \"_stat_site_order\": 1188}, {\"site\": 1193, \"_stat_site_order\": 1189}, {\"site\": 1194, \"_stat_site_order\": 1190}, {\"site\": 1195, \"_stat_site_order\": 1191}, {\"site\": 1196, \"_stat_site_order\": 1192}, {\"site\": 1197, \"_stat_site_order\": 1193}, {\"site\": 1198, \"_stat_site_order\": 1194}, {\"site\": 1199, \"_stat_site_order\": 1195}, {\"site\": 1200, \"_stat_site_order\": 1196}, {\"site\": 1201, \"_stat_site_order\": 1197}, {\"site\": 1202, \"_stat_site_order\": 1198}, {\"site\": 1203, \"_stat_site_order\": 1199}, {\"site\": 1204, \"_stat_site_order\": 1200}, {\"site\": 1205, \"_stat_site_order\": 1201}, {\"site\": 1206, \"_stat_site_order\": 1202}, {\"site\": 1207, \"_stat_site_order\": 1203}, {\"site\": 1208, \"_stat_site_order\": 1204}, {\"site\": 1209, \"_stat_site_order\": 1205}, {\"site\": 1210, \"_stat_site_order\": 1206}, {\"site\": 1211, \"_stat_site_order\": 1207}, {\"site\": 1212, \"_stat_site_order\": 1208}, {\"site\": 1213, \"_stat_site_order\": 1209}, {\"site\": 1214, \"_stat_site_order\": 1210}, {\"site\": 1215, \"_stat_site_order\": 1211}, {\"site\": 1216, \"_stat_site_order\": 1212}, {\"site\": 1217, \"_stat_site_order\": 1213}, {\"site\": 1218, \"_stat_site_order\": 1214}, {\"site\": 1219, \"_stat_site_order\": 1215}, {\"site\": 1220, \"_stat_site_order\": 1216}, {\"site\": 1221, \"_stat_site_order\": 1217}, {\"site\": 1222, \"_stat_site_order\": 1218}, {\"site\": 1223, \"_stat_site_order\": 1219}, {\"site\": 1224, \"_stat_site_order\": 1220}, {\"site\": 1225, \"_stat_site_order\": 1221}, {\"site\": 1226, \"_stat_site_order\": 1222}, {\"site\": 1227, \"_stat_site_order\": 1223}, {\"site\": 1228, \"_stat_site_order\": 1224}, {\"site\": 1229, \"_stat_site_order\": 1225}, {\"site\": 1230, \"_stat_site_order\": 1226}, {\"site\": 1231, \"_stat_site_order\": 1227}, {\"site\": 1232, \"_stat_site_order\": 1228}, {\"site\": 1233, \"_stat_site_order\": 1229}, {\"site\": 1234, \"_stat_site_order\": 1230}, {\"site\": 1235, \"_stat_site_order\": 1231}, {\"site\": 1236, \"_stat_site_order\": 1232}, {\"site\": 1237, \"_stat_site_order\": 1233}, {\"site\": 1238, \"_stat_site_order\": 1234}, {\"site\": 1239, \"_stat_site_order\": 1235}, {\"site\": 1240, \"_stat_site_order\": 1236}, {\"site\": 1241, \"_stat_site_order\": 1237}, {\"site\": 1242, \"_stat_site_order\": 1238}, {\"site\": 1243, \"_stat_site_order\": 1239}, {\"site\": 1244, \"_stat_site_order\": 1240}, {\"site\": 1245, \"_stat_site_order\": 1241}, {\"site\": 1246, \"_stat_site_order\": 1242}, {\"site\": 1247, \"_stat_site_order\": 1243}, {\"site\": 1248, \"_stat_site_order\": 1244}, {\"site\": 1249, \"_stat_site_order\": 1245}, {\"site\": 1250, \"_stat_site_order\": 1246}], \"data-6f4dc25935552d92129204611ad6a7c2\": [{\"site\": 1, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004617954846220116, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": 0.08716449330244418, \"functional effect\": -2.2303, \"times_seen\": 1.0}, {\"site\": 1, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1, \"mutant\": \"T\", \"log2 fold change IC90\": -0.008548139834349237, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": 0.08692736322348117, \"functional effect\": -2.4823, \"times_seen\": 2.0}, {\"site\": 1, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1\", \"IC90\": null, \"functional effect\": -2.3068, \"times_seen\": null}, {\"site\": 2, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 2, \"mutant\": \"I\", \"log2 fold change IC90\": -4.4898450378625164e-05, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.0874412257750654, \"functional effect\": 0.0498, \"times_seen\": 2.0}, {\"site\": 2, \"mutant\": \"L\", \"log2 fold change IC90\": 0.016468531903799346, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08844784886255737, \"functional effect\": 0.2451, \"times_seen\": 14.0}, {\"site\": 2, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013435262989964964, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08663339534843778, \"functional effect\": 0.382, \"times_seen\": 14.0}, {\"site\": 2, \"mutant\": \"V\", \"log2 fold change IC90\": 0.034301361159678995, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": 0.08954791769525651, \"functional effect\": 0.3639, \"times_seen\": 4.0}, {\"site\": 2, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"2\", \"IC90\": null, \"functional effect\": -0.206, \"times_seen\": null}, {\"site\": 3, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0028930473933844476, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08726877078066012, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 3, \"mutant\": \"A\", \"log2 fold change IC90\": -0.040221844002941196, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08503971015641854, \"functional effect\": 0.0936, \"times_seen\": 19.0}, {\"site\": 3, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0034703031773470156, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08723385950403906, \"functional effect\": -0.1408, \"times_seen\": 1.0}, {\"site\": 3, \"mutant\": \"F\", \"log2 fold change IC90\": 0.060285595589282315, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.09117536810988729, \"functional effect\": -0.263, \"times_seen\": 91.0}, {\"site\": 3, \"mutant\": \"G\", \"log2 fold change IC90\": 0.8148730508171046, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.15382643804534515, \"functional effect\": -0.0572, \"times_seen\": 62.0}, {\"site\": 3, \"mutant\": \"I\", \"log2 fold change IC90\": -0.24554475997593583, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.07375872736685142, \"functional effect\": -0.1162, \"times_seen\": 69.0}, {\"site\": 3, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015638159974418017, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08650121300160558, \"functional effect\": -0.052, \"times_seen\": 40.0}, {\"site\": 3, \"mutant\": \"M\", \"log2 fold change IC90\": 0.018195239457023258, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.08855377214876368, \"functional effect\": -0.1206, \"times_seen\": 11.0}, {\"site\": 3, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"3\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 4, \"mutant\": \"-\", \"log2 fold change IC90\": 0.0073519647856731445, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.08789069825024731, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 4, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 4, \"mutant\": \"I\", \"log2 fold change IC90\": 0.09294513792376767, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.09326292397003681, \"functional effect\": 0.1365, \"times_seen\": 35.0}, {\"site\": 4, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03250577957178076, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.08549575230050925, \"functional effect\": 0.1702, \"times_seen\": 26.0}, {\"site\": 4, \"mutant\": \"S\", \"log2 fold change IC90\": 1.5259080120699369, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.25181049983189857, \"functional effect\": -0.4127, \"times_seen\": 28.0}, {\"site\": 4, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03622368127687399, \"epitope\": \"all\", \"reference_site\": \"4\", \"IC90\": 0.08527570886192339, \"functional effect\": -0.3325, \"times_seen\": 10.0}, {\"site\": 5, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004819192519955318, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08715233580826418, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 5, \"mutant\": \"A\", \"log2 fold change IC90\": -0.021396647592762455, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08615663333572188, \"functional effect\": 0.3095, \"times_seen\": 61.0}, {\"site\": 5, \"mutant\": \"C\", \"log2 fold change IC90\": -0.13865056133937523, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.07943131911722658, \"functional effect\": 0.2806, \"times_seen\": 42.0}, {\"site\": 5, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0008478376933428523, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08739257345742446, \"functional effect\": -1.3074, \"times_seen\": 5.0}, {\"site\": 5, \"mutant\": \"E\", \"log2 fold change IC90\": 0.011056843164171817, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08811669390588193, \"functional effect\": -1.5861, \"times_seen\": 7.0}, {\"site\": 5, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0985715563028792, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09362735357223245, \"functional effect\": 0.397, \"times_seen\": 54.0}, {\"site\": 5, \"mutant\": \"G\", \"log2 fold change IC90\": -1.4778381987977784, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.03139468473576611, \"functional effect\": 0.1809, \"times_seen\": 40.0}, {\"site\": 5, \"mutant\": \"H\", \"log2 fold change IC90\": 0.12916371689798026, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09563390860343125, \"functional effect\": 0.2581, \"times_seen\": 53.0}, {\"site\": 5, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02002773887365229, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.088666323890379, \"functional effect\": 0.3636, \"times_seen\": 60.0}, {\"site\": 5, \"mutant\": \"K\", \"log2 fold change IC90\": -0.011801974846682165, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08673152933992136, \"functional effect\": -2.9296, \"times_seen\": 1.0}, {\"site\": 5, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 5, \"mutant\": \"M\", \"log2 fold change IC90\": -0.43241670666703824, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.06479766458939176, \"functional effect\": -0.2568, \"times_seen\": 44.0}, {\"site\": 5, \"mutant\": \"N\", \"log2 fold change IC90\": -0.07434976704393648, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08305164573624996, \"functional effect\": -0.0041, \"times_seen\": 22.0}, {\"site\": 5, \"mutant\": \"P\", \"log2 fold change IC90\": -0.8096341324284186, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.049889091283082866, \"functional effect\": -1.1555, \"times_seen\": 115.0}, {\"site\": 5, \"mutant\": \"Q\", \"log2 fold change IC90\": 1.5774044517177768, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.2609611202809947, \"functional effect\": -0.6278, \"times_seen\": 2.0}, {\"site\": 5, \"mutant\": \"R\", \"log2 fold change IC90\": 0.7175363093798255, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.14379033811269518, \"functional effect\": -0.369, \"times_seen\": 86.0}, {\"site\": 5, \"mutant\": \"S\", \"log2 fold change IC90\": 0.30539600849038145, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.10805953937343843, \"functional effect\": 0.0821, \"times_seen\": 97.0}, {\"site\": 5, \"mutant\": \"T\", \"log2 fold change IC90\": -0.12383152110141607, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08025142459048977, \"functional effect\": 0.2298, \"times_seen\": 85.0}, {\"site\": 5, \"mutant\": \"V\", \"log2 fold change IC90\": 0.057504815336586385, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09099979775974971, \"functional effect\": 0.2278, \"times_seen\": 57.0}, {\"site\": 5, \"mutant\": \"W\", \"log2 fold change IC90\": 0.11383727551773537, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.09462332120511087, \"functional effect\": -0.1663, \"times_seen\": 27.0}, {\"site\": 5, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01708663806683074, \"epitope\": \"all\", \"reference_site\": \"5\", \"IC90\": 0.08641440863143968, \"functional effect\": 0.3396, \"times_seen\": 31.0}, {\"site\": 6, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 6, \"mutant\": \"A\", \"log2 fold change IC90\": 0.017626524002724908, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08851887082019748, \"functional effect\": 0.2169, \"times_seen\": 72.0}, {\"site\": 6, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01566254795319133, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08649975075777988, \"functional effect\": 0.3016, \"times_seen\": 18.0}, {\"site\": 6, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": null, \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 6, \"mutant\": \"F\", \"log2 fold change IC90\": 0.05053319849184056, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.09056111507932599, \"functional effect\": 0.3019, \"times_seen\": 54.0}, {\"site\": 6, \"mutant\": \"I\", \"log2 fold change IC90\": 0.012509182257697482, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08820544430201185, \"functional effect\": 0.374, \"times_seen\": 58.0}, {\"site\": 6, \"mutant\": \"L\", \"log2 fold change IC90\": 0.000868754889025728, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08749661951271039, \"functional effect\": 0.397, \"times_seen\": 44.0}, {\"site\": 6, \"mutant\": \"M\", \"log2 fold change IC90\": -0.09826653178535658, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08168617852259466, \"functional effect\": 0.3992, \"times_seen\": 16.0}, {\"site\": 6, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 6, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0051039244230454426, \"epitope\": \"all\", \"reference_site\": \"6\", \"IC90\": 0.08713513702326231, \"functional effect\": 0.2707, \"times_seen\": 1.0}, {\"site\": 7, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"F\", \"log2 fold change IC90\": -0.11438587713981885, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08077857223454028, \"functional effect\": -0.187, \"times_seen\": 57.0}, {\"site\": 7, \"mutant\": \"I\", \"log2 fold change IC90\": -0.018093341523630485, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08635413023811349, \"functional effect\": -0.2303, \"times_seen\": 11.0}, {\"site\": 7, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"M\", \"log2 fold change IC90\": -0.006351659075401733, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08705980958002786, \"functional effect\": -0.2428, \"times_seen\": 1.0}, {\"site\": 7, \"mutant\": \"P\", \"log2 fold change IC90\": 0.016870028808524083, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": 0.08847246701009864, \"functional effect\": -2.1974, \"times_seen\": 3.0}, {\"site\": 7, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -3.1225, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -3.1479, \"times_seen\": null}, {\"site\": 7, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"7\", \"IC90\": null, \"functional effect\": -0.7825, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": null, \"functional effect\": -1.8655, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"F\", \"log2 fold change IC90\": -2.145146552868699, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.019768617359925845, \"functional effect\": -0.7435, \"times_seen\": 31.0}, {\"site\": 8, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06477233356854507, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08360482410938715, \"functional effect\": 0.0972, \"times_seen\": 8.0}, {\"site\": 8, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03098648625448995, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08558583477829292, \"functional effect\": -2.4719, \"times_seen\": 5.0}, {\"site\": 8, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": null, \"functional effect\": -2.7606, \"times_seen\": null}, {\"site\": 8, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03235970327884309, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08550440938637344, \"functional effect\": -0.6371, \"times_seen\": 10.0}, {\"site\": 8, \"mutant\": \"W\", \"log2 fold change IC90\": -0.03967431060319045, \"epitope\": \"all\", \"reference_site\": \"8\", \"IC90\": 0.08507199065719176, \"functional effect\": -0.2813, \"times_seen\": 19.0}, {\"site\": 9, \"mutant\": \"-\", \"log2 fold change IC90\": -0.00012709361313807986, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.08743624409782666, \"functional effect\": 0.2833, \"times_seen\": 1.0}, {\"site\": 9, \"mutant\": \"L\", \"log2 fold change IC90\": -0.3325784788409277, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.06944063039301895, \"functional effect\": 0.1735, \"times_seen\": 93.0}, {\"site\": 9, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 9, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 9, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.13757218509898536, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.09619291975086121, \"functional effect\": 0.1042, \"times_seen\": 17.0}, {\"site\": 9, \"mutant\": \"R\", \"log2 fold change IC90\": 0.03666066259734122, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.08969447907453558, \"functional effect\": 0.0833, \"times_seen\": 14.0}, {\"site\": 9, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01541778212338238, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.08651442744190022, \"functional effect\": 0.2579, \"times_seen\": 50.0}, {\"site\": 9, \"mutant\": \"T\", \"log2 fold change IC90\": 0.4889988709912161, \"epitope\": \"all\", \"reference_site\": \"9\", \"IC90\": 0.12272501132203396, \"functional effect\": 0.0953, \"times_seen\": 78.0}, {\"site\": 10, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": null, \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 10, \"mutant\": \"I\", \"log2 fold change IC90\": 0.10343729105853634, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.09394366086973106, \"functional effect\": 0.4444, \"times_seen\": 57.0}, {\"site\": 10, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 10, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02207753756064044, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08611598070673937, \"functional effect\": 0.2022, \"times_seen\": 9.0}, {\"site\": 10, \"mutant\": \"P\", \"log2 fold change IC90\": -0.05299531844375728, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08429010063417049, \"functional effect\": -0.8768, \"times_seen\": 11.0}, {\"site\": 10, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0013626506648250455, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08752657844888397, \"functional effect\": 0.1603, \"times_seen\": 3.0}, {\"site\": 10, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011488380026019672, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08675038399310299, \"functional effect\": -0.1532, \"times_seen\": 6.0}, {\"site\": 10, \"mutant\": \"V\", \"log2 fold change IC90\": -0.057608640436333125, \"epitope\": \"all\", \"reference_site\": \"10\", \"IC90\": 0.08402099573022224, \"functional effect\": 0.3729, \"times_seen\": 39.0}, {\"site\": 11, \"mutant\": \"-\", \"log2 fold change IC90\": 0.00454831663349384, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.08772006252473172, \"functional effect\": -0.2745, \"times_seen\": 8.0}, {\"site\": 11, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0022723438344634337, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.08730632528063467, \"functional effect\": -0.1303, \"times_seen\": 5.0}, {\"site\": 11, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": null, \"functional effect\": -1.9748, \"times_seen\": null}, {\"site\": 11, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04597980991657906, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.0847009830517345, \"functional effect\": 0.3549, \"times_seen\": 45.0}, {\"site\": 11, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04913269952421135, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.09047324536056861, \"functional effect\": 0.4444, \"times_seen\": 32.0}, {\"site\": 11, \"mutant\": \"L\", \"log2 fold change IC90\": 0.4649092065162339, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.12069280179754484, \"functional effect\": 0.2851, \"times_seen\": 57.0}, {\"site\": 11, \"mutant\": \"M\", \"log2 fold change IC90\": 0.06387550350701285, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.09140252543311252, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 11, \"mutant\": \"R\", \"log2 fold change IC90\": -0.11965522348619465, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.08048407209522893, \"functional effect\": 0.0913, \"times_seen\": 1.0}, {\"site\": 11, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"11\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": null, \"functional effect\": -3.2561, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": null, \"functional effect\": -1.6629, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02754828091965652, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0857900446658258, \"functional effect\": -0.0764, \"times_seen\": 32.0}, {\"site\": 12, \"mutant\": \"C\", \"log2 fold change IC90\": 0.009247692166676338, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08800626412882424, \"functional effect\": -0.2192, \"times_seen\": 47.0}, {\"site\": 12, \"mutant\": \"D\", \"log2 fold change IC90\": -0.013484732830105152, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08663042475061959, \"functional effect\": 0.0764, \"times_seen\": 3.0}, {\"site\": 12, \"mutant\": \"E\", \"log2 fold change IC90\": -0.027252045492038447, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08580766215200206, \"functional effect\": 0.1186, \"times_seen\": 6.0}, {\"site\": 12, \"mutant\": \"F\", \"log2 fold change IC90\": 0.05472962705314799, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.09082491753571426, \"functional effect\": -0.1239, \"times_seen\": 73.0}, {\"site\": 12, \"mutant\": \"G\", \"log2 fold change IC90\": -0.00643520877235737, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08705476789770157, \"functional effect\": 0.103, \"times_seen\": 8.0}, {\"site\": 12, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0261452186310394, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08904309518096531, \"functional effect\": -0.2061, \"times_seen\": 7.0}, {\"site\": 12, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02564756905887026, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08901238556097509, \"functional effect\": 0.1301, \"times_seen\": 9.0}, {\"site\": 12, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01366882047023577, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0866193714284744, \"functional effect\": 0.0061, \"times_seen\": 4.0}, {\"site\": 12, \"mutant\": \"L\", \"log2 fold change IC90\": 0.38929978284119165, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.11453037026855459, \"functional effect\": 0.0117, \"times_seen\": 36.0}, {\"site\": 12, \"mutant\": \"M\", \"log2 fold change IC90\": -0.019227661034644915, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08628626095580437, \"functional effect\": -0.0662, \"times_seen\": 6.0}, {\"site\": 12, \"mutant\": \"N\", \"log2 fold change IC90\": 0.003981170257591377, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08768558514964872, \"functional effect\": -0.2492, \"times_seen\": 12.0}, {\"site\": 12, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02805046894456714, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08916076485516461, \"functional effect\": -0.0798, \"times_seen\": 63.0}, {\"site\": 12, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010611872969603569, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0868031050633337, \"functional effect\": -0.5121, \"times_seen\": 3.0}, {\"site\": 12, \"mutant\": \"R\", \"log2 fold change IC90\": 0.038462880975546, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08980659566347607, \"functional effect\": -0.2823, \"times_seen\": 22.0}, {\"site\": 12, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 12, \"mutant\": \"T\", \"log2 fold change IC90\": -0.022356326313370936, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08609934112135806, \"functional effect\": 0.0059, \"times_seen\": 44.0}, {\"site\": 12, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05402855039724872, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.08422975520860335, \"functional effect\": -0.3056, \"times_seen\": 13.0}, {\"site\": 12, \"mutant\": \"W\", \"log2 fold change IC90\": -0.005661996084177299, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.0871014374226667, \"functional effect\": 0.0421, \"times_seen\": 1.0}, {\"site\": 12, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0554091914284188, \"epitope\": \"all\", \"reference_site\": \"12\", \"IC90\": 0.09086770961265256, \"functional effect\": -0.2352, \"times_seen\": 47.0}, {\"site\": 13, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": null, \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 13, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004155951210007347, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08719241102615818, \"functional effect\": -0.0454, \"times_seen\": 1.0}, {\"site\": 13, \"mutant\": \"A\", \"log2 fold change IC90\": -0.12015423190281749, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08045623857306362, \"functional effect\": 0.401, \"times_seen\": 15.0}, {\"site\": 13, \"mutant\": \"C\", \"log2 fold change IC90\": 0.03772702971630254, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08976080119947256, \"functional effect\": 0.0129, \"times_seen\": 15.0}, {\"site\": 13, \"mutant\": \"D\", \"log2 fold change IC90\": -0.009793234553117246, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08685237432635123, \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 13, \"mutant\": \"E\", \"log2 fold change IC90\": 0.00676625873500582, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08785502358293186, \"functional effect\": 0.2161, \"times_seen\": 5.0}, {\"site\": 13, \"mutant\": \"F\", \"log2 fold change IC90\": -0.01850288586464085, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.0863296199811959, \"functional effect\": -0.1084, \"times_seen\": 6.0}, {\"site\": 13, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05812431153305767, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08399096897102422, \"functional effect\": -0.029, \"times_seen\": 40.0}, {\"site\": 13, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": null, \"functional effect\": -0.2003, \"times_seen\": null}, {\"site\": 13, \"mutant\": \"I\", \"log2 fold change IC90\": 0.005179114865240081, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.0877584252815573, \"functional effect\": 0.0421, \"times_seen\": 20.0}, {\"site\": 13, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02887407801033787, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08571124218688486, \"functional effect\": -0.1889, \"times_seen\": 3.0}, {\"site\": 13, \"mutant\": \"L\", \"log2 fold change IC90\": 0.22051989218504048, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.10188561118421371, \"functional effect\": 0.289, \"times_seen\": 20.0}, {\"site\": 13, \"mutant\": \"M\", \"log2 fold change IC90\": -0.028528370463482524, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08573178330812183, \"functional effect\": 0.1308, \"times_seen\": 7.0}, {\"site\": 13, \"mutant\": \"N\", \"log2 fold change IC90\": 0.034302027109495724, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.0895479590306957, \"functional effect\": 0.005, \"times_seen\": 24.0}, {\"site\": 13, \"mutant\": \"P\", \"log2 fold change IC90\": -0.00469068169961977, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08716009941505408, \"functional effect\": 0.3762, \"times_seen\": 3.0}, {\"site\": 13, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.00917045644319763, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08800155277587438, \"functional effect\": -0.2887, \"times_seen\": 2.0}, {\"site\": 13, \"mutant\": \"R\", \"log2 fold change IC90\": 0.012986256804825269, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.0882346171553392, \"functional effect\": -0.5151, \"times_seen\": 16.0}, {\"site\": 13, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 13, \"mutant\": \"T\", \"log2 fold change IC90\": -0.016325995540686082, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08645998153703321, \"functional effect\": 0.2847, \"times_seen\": 6.0}, {\"site\": 13, \"mutant\": \"V\", \"log2 fold change IC90\": 0.022459514716829672, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08881590397483784, \"functional effect\": 0.0634, \"times_seen\": 23.0}, {\"site\": 13, \"mutant\": \"W\", \"log2 fold change IC90\": -0.012791811951987838, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": 0.08667204300410511, \"functional effect\": -0.2438, \"times_seen\": 8.0}, {\"site\": 13, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"13\", \"IC90\": null, \"functional effect\": 0.4072, \"times_seen\": null}, {\"site\": 14, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": null, \"functional effect\": -2.7736, \"times_seen\": null}, {\"site\": 14, \"mutant\": \"-\", \"log2 fold change IC90\": 0.012774219435735725, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08822164999266184, \"functional effect\": 0.418, \"times_seen\": 11.0}, {\"site\": 14, \"mutant\": \"H\", \"log2 fold change IC90\": -0.09302907537155945, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08198326509024965, \"functional effect\": 0.4201, \"times_seen\": 72.0}, {\"site\": 14, \"mutant\": \"K\", \"log2 fold change IC90\": 0.001120597979499687, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08751189463451402, \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 14, \"mutant\": \"L\", \"log2 fold change IC90\": 0.019771138520233548, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08865055493978118, \"functional effect\": 0.4294, \"times_seen\": 18.0}, {\"site\": 14, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 14, \"mutant\": \"R\", \"log2 fold change IC90\": 0.011736594096620761, \"epitope\": \"all\", \"reference_site\": \"14\", \"IC90\": 0.08815822140560903, \"functional effect\": -0.1732, \"times_seen\": 45.0}, {\"site\": 15, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": null, \"functional effect\": -3.2502, \"times_seen\": null}, {\"site\": 15, \"mutant\": \"-\", \"log2 fold change IC90\": 0.01420598646283434, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08830924684766304, \"functional effect\": 0.0431, \"times_seen\": 23.0}, {\"site\": 15, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 15, \"mutant\": \"F\", \"log2 fold change IC90\": -1.6463469490823195, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.02793379475880127, \"functional effect\": 0.2209, \"times_seen\": 73.0}, {\"site\": 15, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05127657366260655, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.0843905789040509, \"functional effect\": -0.186, \"times_seen\": 6.0}, {\"site\": 15, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": null, \"functional effect\": 0.6185, \"times_seen\": null}, {\"site\": 15, \"mutant\": \"R\", \"log2 fold change IC90\": 0.46800301275299305, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.1209519007686335, \"functional effect\": 0.251, \"times_seen\": 11.0}, {\"site\": 15, \"mutant\": \"S\", \"log2 fold change IC90\": 0.007416513944215765, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08789463074975262, \"functional effect\": 0.1163, \"times_seen\": 16.0}, {\"site\": 15, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004512878738108958, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08717084200331751, \"functional effect\": 0.1541, \"times_seen\": 1.0}, {\"site\": 15, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03538697747630453, \"epitope\": \"all\", \"reference_site\": \"15\", \"IC90\": 0.08961532713635051, \"functional effect\": 0.0628, \"times_seen\": 28.0}, {\"site\": 16, \"mutant\": \"-\", \"log2 fold change IC90\": -0.1265062120366734, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08010277993508085, \"functional effect\": -0.136, \"times_seen\": 17.0}, {\"site\": 16, \"mutant\": \"A\", \"log2 fold change IC90\": -0.09819637589031725, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08169015088414394, \"functional effect\": -0.1663, \"times_seen\": 68.0}, {\"site\": 16, \"mutant\": \"F\", \"log2 fold change IC90\": -0.1339735952927085, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.07968923945968912, \"functional effect\": 0.0322, \"times_seen\": 65.0}, {\"site\": 16, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": null, \"functional effect\": 0.0858, \"times_seen\": null}, {\"site\": 16, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0363130256733476, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.0896728685778839, \"functional effect\": 0.0386, \"times_seen\": 49.0}, {\"site\": 16, \"mutant\": \"L\", \"log2 fold change IC90\": -0.027482130303268064, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08579397841085341, \"functional effect\": -0.0772, \"times_seen\": 42.0}, {\"site\": 16, \"mutant\": \"M\", \"log2 fold change IC90\": -0.014829364804111895, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.08654972039627896, \"functional effect\": 0.2404, \"times_seen\": 22.0}, {\"site\": 16, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 16, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"16\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 17, \"mutant\": \"-\", \"log2 fold change IC90\": -0.002294465298408791, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.0873049865854391, \"functional effect\": 0.0501, \"times_seen\": 1.0}, {\"site\": 17, \"mutant\": \"D\", \"log2 fold change IC90\": 0.30504213892483345, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.10803303738108952, \"functional effect\": -0.376, \"times_seen\": 60.0}, {\"site\": 17, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": null, \"functional effect\": -0.8797, \"times_seen\": null}, {\"site\": 17, \"mutant\": \"I\", \"log2 fold change IC90\": 0.007648822281990934, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08790878502284831, \"functional effect\": -0.5785, \"times_seen\": 11.0}, {\"site\": 17, \"mutant\": \"K\", \"log2 fold change IC90\": 0.23944080051921296, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.10323063907705261, \"functional effect\": -0.4162, \"times_seen\": 36.0}, {\"site\": 17, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 17, \"mutant\": \"R\", \"log2 fold change IC90\": -9.870735256940031e-05, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08743796449774179, \"functional effect\": -0.511, \"times_seen\": 9.0}, {\"site\": 17, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06007652554573749, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.0838773916360474, \"functional effect\": -0.554, \"times_seen\": 31.0}, {\"site\": 17, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04126272268831211, \"epitope\": \"all\", \"reference_site\": \"17\", \"IC90\": 0.08497837765334737, \"functional effect\": -0.5979, \"times_seen\": 19.0}, {\"site\": 18, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0019884348871230116, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08732350804296073, \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 18, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004486458559422682, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08717243838387262, \"functional effect\": 0.0466, \"times_seen\": 1.0}, {\"site\": 18, \"mutant\": \"A\", \"log2 fold change IC90\": -0.11424801530698235, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08078629168584975, \"functional effect\": -0.1471, \"times_seen\": 45.0}, {\"site\": 18, \"mutant\": \"C\", \"log2 fold change IC90\": 0.007851541112536114, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08792113830450621, \"functional effect\": -0.6401, \"times_seen\": 21.0}, {\"site\": 18, \"mutant\": \"D\", \"log2 fold change IC90\": -0.014006017971907151, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08659912846530958, \"functional effect\": -0.2457, \"times_seen\": 13.0}, {\"site\": 18, \"mutant\": \"E\", \"log2 fold change IC90\": -0.019923783975923516, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08624463652718878, \"functional effect\": 0.0624, \"times_seen\": 26.0}, {\"site\": 18, \"mutant\": \"F\", \"log2 fold change IC90\": 0.2905227405690389, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.10695123704009767, \"functional effect\": -0.0948, \"times_seen\": 42.0}, {\"site\": 18, \"mutant\": \"G\", \"log2 fold change IC90\": -0.09483595402618607, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08188065082845389, \"functional effect\": -0.2994, \"times_seen\": 25.0}, {\"site\": 18, \"mutant\": \"H\", \"log2 fold change IC90\": 0.00794294938234389, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08792670911019301, \"functional effect\": -0.2382, \"times_seen\": 24.0}, {\"site\": 18, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0010880912185848412, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08737802109183021, \"functional effect\": -0.1222, \"times_seen\": 25.0}, {\"site\": 18, \"mutant\": \"K\", \"log2 fold change IC90\": -0.049261732680737774, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08450851954999788, \"functional effect\": 0.2198, \"times_seen\": 55.0}, {\"site\": 18, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 18, \"mutant\": \"M\", \"log2 fold change IC90\": -0.004477074426029407, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08717300540630447, \"functional effect\": -0.0761, \"times_seen\": 38.0}, {\"site\": 18, \"mutant\": \"N\", \"log2 fold change IC90\": -0.015208312665886126, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08652698965729333, \"functional effect\": -0.3196, \"times_seen\": 9.0}, {\"site\": 18, \"mutant\": \"P\", \"log2 fold change IC90\": -0.6179668443014767, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.05697747462247945, \"functional effect\": -0.031, \"times_seen\": 147.0}, {\"site\": 18, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.054046935828056454, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08422868180748602, \"functional effect\": -0.1973, \"times_seen\": 51.0}, {\"site\": 18, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08535241372672377, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08242066534930649, \"functional effect\": -0.1738, \"times_seen\": 65.0}, {\"site\": 18, \"mutant\": \"S\", \"log2 fold change IC90\": -0.6387023835891447, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.056164406899586246, \"functional effect\": 0.0239, \"times_seen\": 50.0}, {\"site\": 18, \"mutant\": \"T\", \"log2 fold change IC90\": -0.027689184394671384, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.0857816662318618, \"functional effect\": -0.0798, \"times_seen\": 47.0}, {\"site\": 18, \"mutant\": \"V\", \"log2 fold change IC90\": 0.18267839950130557, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.09924792385772227, \"functional effect\": 0.017, \"times_seen\": 51.0}, {\"site\": 18, \"mutant\": \"W\", \"log2 fold change IC90\": 0.08614773952716236, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.0928245401624813, \"functional effect\": -0.0637, \"times_seen\": 27.0}, {\"site\": 18, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005021966295019799, \"epitope\": \"all\", \"reference_site\": \"18\", \"IC90\": 0.08714008722782121, \"functional effect\": -0.1084, \"times_seen\": 14.0}, {\"site\": 19, \"mutant\": \"*\", \"log2 fold change IC90\": -0.010602622524362011, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0868036616396868, \"functional effect\": -3.0652, \"times_seen\": 3.0}, {\"site\": 19, \"mutant\": \"-\", \"log2 fold change IC90\": -0.002701910088151937, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08728033346176085, \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 19, \"mutant\": \"A\", \"log2 fold change IC90\": 0.4140112696976122, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.11650902383134196, \"functional effect\": -0.24, \"times_seen\": 89.0}, {\"site\": 19, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04369693566344779, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08483511726120183, \"functional effect\": -0.6944, \"times_seen\": 24.0}, {\"site\": 19, \"mutant\": \"D\", \"log2 fold change IC90\": -0.09387976967756051, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08193493738636758, \"functional effect\": 0.0872, \"times_seen\": 13.0}, {\"site\": 19, \"mutant\": \"E\", \"log2 fold change IC90\": 2.022368733568924, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.3552412617473871, \"functional effect\": 0.3967, \"times_seen\": 7.0}, {\"site\": 19, \"mutant\": \"F\", \"log2 fold change IC90\": 0.003903109776174533, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0876808408387425, \"functional effect\": -0.2889, \"times_seen\": 31.0}, {\"site\": 19, \"mutant\": \"G\", \"log2 fold change IC90\": 0.04454871392431418, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.09018623399238429, \"functional effect\": -0.3205, \"times_seen\": 24.0}, {\"site\": 19, \"mutant\": \"H\", \"log2 fold change IC90\": -0.010622697978820145, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08680245375390207, \"functional effect\": -0.9589, \"times_seen\": 20.0}, {\"site\": 19, \"mutant\": \"I\", \"log2 fold change IC90\": -0.00453503952527947, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08716950300956919, \"functional effect\": -0.2361, \"times_seen\": 81.0}, {\"site\": 19, \"mutant\": \"K\", \"log2 fold change IC90\": 0.8263704670887121, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.15505724058370982, \"functional effect\": 0.2149, \"times_seen\": 54.0}, {\"site\": 19, \"mutant\": \"L\", \"log2 fold change IC90\": 0.22773933603068933, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.10239673856501268, \"functional effect\": -0.2714, \"times_seen\": 60.0}, {\"site\": 19, \"mutant\": \"M\", \"log2 fold change IC90\": 0.002577463868577796, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0876003107480631, \"functional effect\": 0.03, \"times_seen\": 25.0}, {\"site\": 19, \"mutant\": \"N\", \"log2 fold change IC90\": 0.027155065711145968, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08910544473177538, \"functional effect\": -0.1833, \"times_seen\": 49.0}, {\"site\": 19, \"mutant\": \"P\", \"log2 fold change IC90\": -0.01814392199986376, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.086351102740034, \"functional effect\": -0.0513, \"times_seen\": 105.0}, {\"site\": 19, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.093073282372128, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0819807530009879, \"functional effect\": -0.5133, \"times_seen\": 17.0}, {\"site\": 19, \"mutant\": \"R\", \"log2 fold change IC90\": 0.00448731825223946, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08771635372380729, \"functional effect\": -0.0266, \"times_seen\": 91.0}, {\"site\": 19, \"mutant\": \"S\", \"log2 fold change IC90\": 0.4089001763184619, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.11609699294638394, \"functional effect\": -0.3007, \"times_seen\": 133.0}, {\"site\": 19, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 19, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011465962056902156, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08675173201363684, \"functional effect\": -0.1003, \"times_seen\": 17.0}, {\"site\": 19, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0354371427457686, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.08532221274234915, \"functional effect\": 0.0735, \"times_seen\": 21.0}, {\"site\": 19, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.4118660750955201, \"epitope\": \"all\", \"reference_site\": \"19\", \"IC90\": 0.06572728754178943, \"functional effect\": -0.0945, \"times_seen\": 25.0}, {\"site\": 20, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004044159253652686, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.08719916767783882, \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 20, \"mutant\": \"A\", \"log2 fold change IC90\": 0.1655567311272917, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.09807702750413595, \"functional effect\": 0.2419, \"times_seen\": 60.0}, {\"site\": 20, \"mutant\": \"I\", \"log2 fold change IC90\": -0.1766941931631684, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.07736410409689268, \"functional effect\": 0.2046, \"times_seen\": 77.0}, {\"site\": 20, \"mutant\": \"N\", \"log2 fold change IC90\": -0.20326093759416447, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.07595250704619683, \"functional effect\": 0.383, \"times_seen\": 82.0}, {\"site\": 20, \"mutant\": \"P\", \"log2 fold change IC90\": -0.032527348958575696, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.08549447408362126, \"functional effect\": -0.0425, \"times_seen\": 28.0}, {\"site\": 20, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0628907739407941, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.08371393246693773, \"functional effect\": 0.0782, \"times_seen\": 12.0}, {\"site\": 20, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"20\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 21, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0004906247038347612, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08741421464051374, \"functional effect\": -0.0923, \"times_seen\": 2.0}, {\"site\": 21, \"mutant\": \"E\", \"log2 fold change IC90\": -0.040804914489460886, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08500534799025583, \"functional effect\": 0.3483, \"times_seen\": 35.0}, {\"site\": 21, \"mutant\": \"G\", \"log2 fold change IC90\": 0.12855306653221868, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.0955934381491131, \"functional effect\": 0.3186, \"times_seen\": 138.0}, {\"site\": 21, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03683617299096172, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08970539147839258, \"functional effect\": 0.0568, \"times_seen\": 78.0}, {\"site\": 21, \"mutant\": \"K\", \"log2 fold change IC90\": 0.4200866648904796, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.11700069451836494, \"functional effect\": 0.3517, \"times_seen\": 97.0}, {\"site\": 21, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0029599537398915373, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08726472370275178, \"functional effect\": 0.157, \"times_seen\": 5.0}, {\"site\": 21, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00257540132263483, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08728798733944217, \"functional effect\": 0.3257, \"times_seen\": 1.0}, {\"site\": 21, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 21, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0468491189400165, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.09033015238847444, \"functional effect\": -0.0945, \"times_seen\": 130.0}, {\"site\": 21, \"mutant\": \"T\", \"log2 fold change IC90\": 0.4938354351743901, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.12313713130776567, \"functional effect\": 0.1923, \"times_seen\": 105.0}, {\"site\": 21, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004625624244134987, \"epitope\": \"all\", \"reference_site\": \"21\", \"IC90\": 0.08716402993535179, \"functional effect\": 0.2954, \"times_seen\": 3.0}, {\"site\": 22, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": null, \"functional effect\": 0.0432, \"times_seen\": null}, {\"site\": 22, \"mutant\": \"A\", \"log2 fold change IC90\": 0.20929946790549536, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.10109627893333568, \"functional effect\": -0.2283, \"times_seen\": 109.0}, {\"site\": 22, \"mutant\": \"I\", \"log2 fold change IC90\": -0.20236642968967888, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.0759996141496755, \"functional effect\": 0.1231, \"times_seen\": 79.0}, {\"site\": 22, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01962362188686697, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08864149081848426, \"functional effect\": 0.1078, \"times_seen\": 7.0}, {\"site\": 22, \"mutant\": \"N\", \"log2 fold change IC90\": -0.10290165750114412, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08142415632254836, \"functional effect\": -0.1722, \"times_seen\": 83.0}, {\"site\": 22, \"mutant\": \"P\", \"log2 fold change IC90\": -0.10357188194456912, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08138633836098066, \"functional effect\": -0.1872, \"times_seen\": 24.0}, {\"site\": 22, \"mutant\": \"S\", \"log2 fold change IC90\": -0.026549490037111063, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.08584945845706297, \"functional effect\": 0.1051, \"times_seen\": 23.0}, {\"site\": 22, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"22\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 23, \"mutant\": \"*\", \"log2 fold change IC90\": 0.021121397390358395, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08873356432713862, \"functional effect\": -2.3803, \"times_seen\": 2.0}, {\"site\": 23, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": null, \"functional effect\": -1.1418, \"times_seen\": null}, {\"site\": 23, \"mutant\": \"E\", \"log2 fold change IC90\": 0.030670291835568658, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08932282102164514, \"functional effect\": 0.0926, \"times_seen\": 15.0}, {\"site\": 23, \"mutant\": \"H\", \"log2 fold change IC90\": -0.11720838515689734, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08062069043879305, \"functional effect\": 0.0352, \"times_seen\": 141.0}, {\"site\": 23, \"mutant\": \"K\", \"log2 fold change IC90\": -0.301775432500462, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.07093920149884872, \"functional effect\": 0.1144, \"times_seen\": 36.0}, {\"site\": 23, \"mutant\": \"L\", \"log2 fold change IC90\": -0.17783527752813638, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.07730293797055403, \"functional effect\": 0.0207, \"times_seen\": 62.0}, {\"site\": 23, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01105013486712835, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.08811628417855484, \"functional effect\": 0.0088, \"times_seen\": 28.0}, {\"site\": 23, \"mutant\": \"P\", \"log2 fold change IC90\": -0.1098018035925684, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.0810356493185694, \"functional effect\": -0.2311, \"times_seen\": 30.0}, {\"site\": 23, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 23, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0525416053320456, \"epitope\": \"all\", \"reference_site\": \"23\", \"IC90\": 0.0843166131936469, \"functional effect\": -0.0953, \"times_seen\": 60.0}, {\"site\": 24, \"mutant\": \"-\", \"log2 fold change IC90\": -1.23323658355887, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.03719534141351815, \"functional effect\": 0.0184, \"times_seen\": 59.0}, {\"site\": 24, \"mutant\": \"F\", \"log2 fold change IC90\": -0.17089826840386818, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.07767553403991229, \"functional effect\": -0.2565, \"times_seen\": 36.0}, {\"site\": 24, \"mutant\": \"H\", \"log2 fold change IC90\": -0.00775379187267743, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08697523861290622, \"functional effect\": 0.2929, \"times_seen\": 1.0}, {\"site\": 24, \"mutant\": \"I\", \"log2 fold change IC90\": 0.014582290740153445, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.0883322839280308, \"functional effect\": -0.4616, \"times_seen\": 23.0}, {\"site\": 24, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 24, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0011243560811579007, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08751212259608274, \"functional effect\": -0.0642, \"times_seen\": 2.0}, {\"site\": 24, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009542043841706847, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08686749769507858, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 24, \"mutant\": \"R\", \"log2 fold change IC90\": 0.006668496255888145, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08784907039555509, \"functional effect\": -0.0902, \"times_seen\": 1.0}, {\"site\": 24, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05777467318000179, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08401132671955129, \"functional effect\": -0.1515, \"times_seen\": 23.0}, {\"site\": 24, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0008480091399402515, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08749536133283743, \"functional effect\": 0.1116, \"times_seen\": 3.0}, {\"site\": 24, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07777845078980303, \"epitope\": \"all\", \"reference_site\": \"24\", \"IC90\": 0.08285450100890918, \"functional effect\": -0.1582, \"times_seen\": 14.0}, {\"site\": 25, \"mutant\": \"-\", \"log2 fold change IC90\": -0.2195371420839861, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.0751004411117406, \"functional effect\": -0.0124, \"times_seen\": 91.0}, {\"site\": 25, \"mutant\": \"A\", \"log2 fold change IC90\": 0.015723681554247308, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.0884021958274577, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"mutant\": \"H\", \"log2 fold change IC90\": -0.22626721261161523, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.07475091873765202, \"functional effect\": -0.0359, \"times_seen\": 106.0}, {\"site\": 25, \"mutant\": \"L\", \"log2 fold change IC90\": -0.6188928729240895, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.056940913990507415, \"functional effect\": 0.0811, \"times_seen\": 119.0}, {\"site\": 25, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0032844144597162306, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.0876432472422369, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 25, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 25, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01327760938793893, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.08825243795521738, \"functional effect\": -0.1673, \"times_seen\": 73.0}, {\"site\": 25, \"mutant\": \"T\", \"log2 fold change IC90\": -0.9101172164138327, \"epitope\": \"all\", \"reference_site\": \"25\", \"IC90\": 0.04653258411911951, \"functional effect\": -0.2096, \"times_seen\": 102.0}, {\"site\": 26, \"mutant\": \"*\", \"log2 fold change IC90\": -0.06520302058452039, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08357986932886938, \"functional effect\": -2.9872, \"times_seen\": 8.0}, {\"site\": 26, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": null, \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 26, \"mutant\": \"A\", \"log2 fold change IC90\": -0.3059981159998712, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07073187020125297, \"functional effect\": 0.0665, \"times_seen\": 177.0}, {\"site\": 26, \"mutant\": \"C\", \"log2 fold change IC90\": -0.2845932217438004, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07178912442781467, \"functional effect\": -0.25, \"times_seen\": 43.0}, {\"site\": 26, \"mutant\": \"D\", \"log2 fold change IC90\": -1.1640431573132333, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.03902274771884253, \"functional effect\": -0.0853, \"times_seen\": 38.0}, {\"site\": 26, \"mutant\": \"E\", \"log2 fold change IC90\": -0.03983000160890308, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08506281045710935, \"functional effect\": -0.1077, \"times_seen\": 73.0}, {\"site\": 26, \"mutant\": \"F\", \"log2 fold change IC90\": -0.4516582035561361, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.06393918345761974, \"functional effect\": -0.1031, \"times_seen\": 73.0}, {\"site\": 26, \"mutant\": \"G\", \"log2 fold change IC90\": -0.01581318474084219, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08649071949061315, \"functional effect\": -0.2147, \"times_seen\": 110.0}, {\"site\": 26, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0020487342793065787, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08756821221804133, \"functional effect\": -0.082, \"times_seen\": 157.0}, {\"site\": 26, \"mutant\": \"I\", \"log2 fold change IC90\": -0.023578637000784886, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08602642510477472, \"functional effect\": 0.0365, \"times_seen\": 47.0}, {\"site\": 26, \"mutant\": \"K\", \"log2 fold change IC90\": -0.15493702346212537, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07853966803944457, \"functional effect\": -0.11, \"times_seen\": 62.0}, {\"site\": 26, \"mutant\": \"L\", \"log2 fold change IC90\": -0.061315950065942926, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08380536321032357, \"functional effect\": -0.0377, \"times_seen\": 300.0}, {\"site\": 26, \"mutant\": \"M\", \"log2 fold change IC90\": -0.9690480055656646, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.04467013201013006, \"functional effect\": 0.0335, \"times_seen\": 74.0}, {\"site\": 26, \"mutant\": \"N\", \"log2 fold change IC90\": -0.13094910584032696, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.0798564765211436, \"functional effect\": -0.2281, \"times_seen\": 43.0}, {\"site\": 26, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 26, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.32774799925895726, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.10974676605977336, \"functional effect\": -0.125, \"times_seen\": 96.0}, {\"site\": 26, \"mutant\": \"R\", \"log2 fold change IC90\": -0.195108766398768, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.07638290328537917, \"functional effect\": -0.0945, \"times_seen\": 207.0}, {\"site\": 26, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06187795076268578, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08377272325610845, \"functional effect\": -0.0988, \"times_seen\": 185.0}, {\"site\": 26, \"mutant\": \"T\", \"log2 fold change IC90\": 0.09483702407858388, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.09338530504839697, \"functional effect\": 0.0287, \"times_seen\": 161.0}, {\"site\": 26, \"mutant\": \"V\", \"log2 fold change IC90\": 0.022521722941522743, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08881973375083008, \"functional effect\": -0.0265, \"times_seen\": 122.0}, {\"site\": 26, \"mutant\": \"W\", \"log2 fold change IC90\": 0.03275122881356876, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.08945175282857887, \"functional effect\": -0.2387, \"times_seen\": 26.0}, {\"site\": 26, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.16417398501293104, \"epitope\": \"all\", \"reference_site\": \"26\", \"IC90\": 0.0780384183705258, \"functional effect\": 0.033, \"times_seen\": 53.0}, {\"site\": 27, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": null, \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 27, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 27, \"mutant\": \"D\", \"log2 fold change IC90\": 0.25966585610460835, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.10468801480226485, \"functional effect\": -0.1383, \"times_seen\": 5.0}, {\"site\": 27, \"mutant\": \"E\", \"log2 fold change IC90\": -0.08852112481100406, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08223983664563926, \"functional effect\": -0.081, \"times_seen\": 11.0}, {\"site\": 27, \"mutant\": \"G\", \"log2 fold change IC90\": 0.02364772634295909, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08888908337660743, \"functional effect\": 0.0321, \"times_seen\": 27.0}, {\"site\": 27, \"mutant\": \"L\", \"log2 fold change IC90\": 0.006432342136272443, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08783469159654507, \"functional effect\": -0.2663, \"times_seen\": 13.0}, {\"site\": 27, \"mutant\": \"P\", \"log2 fold change IC90\": -0.051580520154671336, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08437280139883029, \"functional effect\": -0.7404, \"times_seen\": 29.0}, {\"site\": 27, \"mutant\": \"S\", \"log2 fold change IC90\": 0.10609018356846318, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.09411656762301675, \"functional effect\": -0.2984, \"times_seen\": 57.0}, {\"site\": 27, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013561481397095768, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08662581630328905, \"functional effect\": -0.1758, \"times_seen\": 107.0}, {\"site\": 27, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02357173878280899, \"epitope\": \"all\", \"reference_site\": \"27\", \"IC90\": 0.08602683643941855, \"functional effect\": -0.2406, \"times_seen\": 70.0}, {\"site\": 28, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": null, \"functional effect\": -2.7365, \"times_seen\": null}, {\"site\": 28, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": null, \"functional effect\": 0.0033, \"times_seen\": null}, {\"site\": 28, \"mutant\": \"C\", \"log2 fold change IC90\": -0.18038096449972477, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.07716665444709644, \"functional effect\": -0.1402, \"times_seen\": 34.0}, {\"site\": 28, \"mutant\": \"D\", \"log2 fold change IC90\": 0.02083385260679129, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08871588052682063, \"functional effect\": -0.1212, \"times_seen\": 26.0}, {\"site\": 28, \"mutant\": \"F\", \"log2 fold change IC90\": 0.018150276010775578, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08855101229958233, \"functional effect\": -0.0107, \"times_seen\": 25.0}, {\"site\": 28, \"mutant\": \"H\", \"log2 fold change IC90\": 0.3725699590481754, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.11320992064665927, \"functional effect\": -0.2076, \"times_seen\": 147.0}, {\"site\": 28, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0038115149796054825, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08721323026364733, \"functional effect\": -0.3199, \"times_seen\": 1.0}, {\"site\": 28, \"mutant\": \"N\", \"log2 fold change IC90\": 0.08220530425842307, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.09257122593758003, \"functional effect\": -0.034, \"times_seen\": 30.0}, {\"site\": 28, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0024956248244918707, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.08729281422405515, \"functional effect\": 0.2182, \"times_seen\": 1.0}, {\"site\": 28, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 28, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"28\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 29, \"mutant\": \"*\", \"log2 fold change IC90\": 0.026741955530673243, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08907993338283422, \"functional effect\": -2.7073, \"times_seen\": 1.0}, {\"site\": 29, \"mutant\": \"A\", \"log2 fold change IC90\": 0.031847014494764354, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08939570618550977, \"functional effect\": -0.0217, \"times_seen\": 135.0}, {\"site\": 29, \"mutant\": \"C\", \"log2 fold change IC90\": -0.002296534926683936, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08730486134154897, \"functional effect\": 0.0151, \"times_seen\": 37.0}, {\"site\": 29, \"mutant\": \"D\", \"log2 fold change IC90\": 0.10065714994339255, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09376280134055569, \"functional effect\": -0.9919, \"times_seen\": 35.0}, {\"site\": 29, \"mutant\": \"E\", \"log2 fold change IC90\": 0.056865880692873655, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09095950507933757, \"functional effect\": -0.6248, \"times_seen\": 22.0}, {\"site\": 29, \"mutant\": \"F\", \"log2 fold change IC90\": 0.23065164316229883, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.10260365127964333, \"functional effect\": -0.3225, \"times_seen\": 60.0}, {\"site\": 29, \"mutant\": \"G\", \"log2 fold change IC90\": 0.010094073360476923, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08805790962460452, \"functional effect\": -0.2236, \"times_seen\": 19.0}, {\"site\": 29, \"mutant\": \"H\", \"log2 fold change IC90\": -0.19605079707633075, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.07633304413350273, \"functional effect\": -0.2165, \"times_seen\": 76.0}, {\"site\": 29, \"mutant\": \"I\", \"log2 fold change IC90\": -0.18786698392811993, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.07676728042524253, \"functional effect\": -0.1728, \"times_seen\": 144.0}, {\"site\": 29, \"mutant\": \"K\", \"log2 fold change IC90\": 0.042550294660969816, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09006139462391315, \"functional effect\": -0.0741, \"times_seen\": 29.0}, {\"site\": 29, \"mutant\": \"L\", \"log2 fold change IC90\": -0.19293213444106322, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.07649823115800876, \"functional effect\": -0.2727, \"times_seen\": 120.0}, {\"site\": 29, \"mutant\": \"M\", \"log2 fold change IC90\": 0.08700378340163674, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09287963528400231, \"functional effect\": -0.0634, \"times_seen\": 31.0}, {\"site\": 29, \"mutant\": \"N\", \"log2 fold change IC90\": 0.043856743746002555, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09014298769370158, \"functional effect\": -1.1027, \"times_seen\": 54.0}, {\"site\": 29, \"mutant\": \"P\", \"log2 fold change IC90\": -0.212498620051515, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.07546773124111401, \"functional effect\": -0.7726, \"times_seen\": 117.0}, {\"site\": 29, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05768082539529404, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.08401679186161007, \"functional effect\": -0.2614, \"times_seen\": 22.0}, {\"site\": 29, \"mutant\": \"R\", \"log2 fold change IC90\": 0.13032628339626984, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09571100430523358, \"functional effect\": -0.0754, \"times_seen\": 56.0}, {\"site\": 29, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0030098954638405574, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.0872617029151383, \"functional effect\": -0.1188, \"times_seen\": 187.0}, {\"site\": 29, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 29, \"mutant\": \"V\", \"log2 fold change IC90\": 0.05989512431327519, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.09115069446512845, \"functional effect\": -0.1554, \"times_seen\": 63.0}, {\"site\": 29, \"mutant\": \"W\", \"log2 fold change IC90\": -0.08597793371669502, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.0823849373560665, \"functional effect\": -0.3719, \"times_seen\": 28.0}, {\"site\": 29, \"mutant\": \"Y\", \"log2 fold change IC90\": -2.148628665173112, \"epitope\": \"all\", \"reference_site\": \"29\", \"IC90\": 0.019720961037493847, \"functional effect\": -0.2473, \"times_seen\": 56.0}, {\"site\": 30, \"mutant\": \"D\", \"log2 fold change IC90\": -0.13247321818974556, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.07977215795637232, \"functional effect\": -0.2915, \"times_seen\": 19.0}, {\"site\": 30, \"mutant\": \"G\", \"log2 fold change IC90\": -0.005626816368414651, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08710356139279508, \"functional effect\": -1.4364, \"times_seen\": 1.0}, {\"site\": 30, \"mutant\": \"H\", \"log2 fold change IC90\": 0.02107198661990233, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08873052534899363, \"functional effect\": -0.1785, \"times_seen\": 95.0}, {\"site\": 30, \"mutant\": \"I\", \"log2 fold change IC90\": -0.024521035926615607, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08597024917336558, \"functional effect\": 0.0096, \"times_seen\": 25.0}, {\"site\": 30, \"mutant\": \"K\", \"log2 fold change IC90\": -0.012602788048763768, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08668339963923519, \"functional effect\": 0.1346, \"times_seen\": 72.0}, {\"site\": 30, \"mutant\": \"L\", \"log2 fold change IC90\": 0.010496675885878793, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08808248674101929, \"functional effect\": -0.1372, \"times_seen\": 13.0}, {\"site\": 30, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 30, \"mutant\": \"S\", \"log2 fold change IC90\": 0.16290710036358905, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.09789706610320328, \"functional effect\": 0.1031, \"times_seen\": 93.0}, {\"site\": 30, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03960425990632322, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08507612146567335, \"functional effect\": 0.0444, \"times_seen\": 42.0}, {\"site\": 30, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12757847677012746, \"epitope\": \"all\", \"reference_site\": \"30\", \"IC90\": 0.08004326668203085, \"functional effect\": -0.1011, \"times_seen\": 33.0}, {\"site\": 31, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": null, \"functional effect\": 0.1285, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0674575201814737, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08344936106298756, \"functional effect\": -1.6643, \"times_seen\": 14.0}, {\"site\": 31, \"mutant\": \"I\", \"log2 fold change IC90\": 0.1855817373264066, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.09944785549984118, \"functional effect\": -0.6806, \"times_seen\": 12.0}, {\"site\": 31, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": null, \"functional effect\": -3.1061, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"P\", \"log2 fold change IC90\": 0.027484321523148014, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.0891257829410551, \"functional effect\": -2.6768, \"times_seen\": 1.0}, {\"site\": 31, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 31, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013240299811123634, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08664510361871479, \"functional effect\": -0.5595, \"times_seen\": 3.0}, {\"site\": 31, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.020963190153797818, \"epitope\": \"all\", \"reference_site\": \"31\", \"IC90\": 0.08872383425813113, \"functional effect\": -2.2492, \"times_seen\": 3.0}, {\"site\": 32, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 32, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": null, \"functional effect\": -2.098, \"times_seen\": null}, {\"site\": 32, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 32, \"mutant\": \"I\", \"log2 fold change IC90\": -0.027434715050506486, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.08579679814052961, \"functional effect\": 0.3272, \"times_seen\": 4.0}, {\"site\": 32, \"mutant\": \"L\", \"log2 fold change IC90\": 0.11632843353217892, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.09478685214572778, \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 32, \"mutant\": \"S\", \"log2 fold change IC90\": -1.2795464345471421, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.036020347242584745, \"functional effect\": 0.2503, \"times_seen\": 32.0}, {\"site\": 32, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011357738701369071, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.08675823991407298, \"functional effect\": 0.2702, \"times_seen\": 7.0}, {\"site\": 32, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.6250536415259356, \"epitope\": \"all\", \"reference_site\": \"32\", \"IC90\": 0.05669827654003618, \"functional effect\": -0.0009, \"times_seen\": 27.0}, {\"site\": 33, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 33, \"mutant\": \"A\", \"log2 fold change IC90\": -0.12349637411337441, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.0802700696587637, \"functional effect\": -0.5022, \"times_seen\": 11.0}, {\"site\": 33, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06712482541123081, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.09160861953263544, \"functional effect\": -0.3319, \"times_seen\": 74.0}, {\"site\": 33, \"mutant\": \"K\", \"log2 fold change IC90\": 0.1367064068616747, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.09613521056772276, \"functional effect\": -0.0638, \"times_seen\": 14.0}, {\"site\": 33, \"mutant\": \"N\", \"log2 fold change IC90\": -0.021624038214424688, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.08614305481357792, \"functional effect\": -0.0747, \"times_seen\": 4.0}, {\"site\": 33, \"mutant\": \"R\", \"log2 fold change IC90\": -0.39495345143886085, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.06650233848008609, \"functional effect\": -0.1335, \"times_seen\": 6.0}, {\"site\": 33, \"mutant\": \"S\", \"log2 fold change IC90\": -0.019201418584840046, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.08628783050681978, \"functional effect\": -0.1264, \"times_seen\": 16.0}, {\"site\": 33, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"33\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 34, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 34, \"mutant\": \"C\", \"log2 fold change IC90\": -0.007826884961476498, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08697083218769638, \"functional effect\": -1.913, \"times_seen\": 3.0}, {\"site\": 34, \"mutant\": \"G\", \"log2 fold change IC90\": -0.058717128670889795, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08395646337146061, \"functional effect\": -2.8329, \"times_seen\": 2.0}, {\"site\": 34, \"mutant\": \"H\", \"log2 fold change IC90\": 0.015996162501729156, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08841889387401221, \"functional effect\": 0.0507, \"times_seen\": 7.0}, {\"site\": 34, \"mutant\": \"K\", \"log2 fold change IC90\": -0.015949338695775847, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08648255733747164, \"functional effect\": -0.6047, \"times_seen\": 13.0}, {\"site\": 34, \"mutant\": \"L\", \"log2 fold change IC90\": -0.006669784691985803, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08704061432291964, \"functional effect\": -1.2083, \"times_seen\": 15.0}, {\"site\": 34, \"mutant\": \"M\", \"log2 fold change IC90\": -0.011548251463865773, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08674678395130235, \"functional effect\": -2.7512, \"times_seen\": 3.0}, {\"site\": 34, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005405162902193769, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08711694487923245, \"functional effect\": -2.963, \"times_seen\": 1.0}, {\"site\": 34, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 34, \"mutant\": \"S\", \"log2 fold change IC90\": -0.002657025929270744, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08728304891109927, \"functional effect\": -1.472, \"times_seen\": 1.0}, {\"site\": 34, \"mutant\": \"T\", \"log2 fold change IC90\": -0.033738894846976286, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": 0.08542270770513699, \"functional effect\": -1.6049, \"times_seen\": 3.0}, {\"site\": 34, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"34\", \"IC90\": null, \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -0.7648, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"C\", \"log2 fold change IC90\": -0.40047869398756736, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.06624813449229887, \"functional effect\": -0.7398, \"times_seen\": 31.0}, {\"site\": 35, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -1.9509, \"times_seen\": null}, {\"site\": 35, \"mutant\": \"R\", \"log2 fold change IC90\": 0.012633952845259502, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.0882130730251398, \"functional effect\": -2.2796, \"times_seen\": 7.0}, {\"site\": 35, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05731604303386923, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.0840380380139939, \"functional effect\": -0.2414, \"times_seen\": 15.0}, {\"site\": 35, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04352121400742665, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": 0.0901220254422399, \"functional effect\": -0.5298, \"times_seen\": 21.0}, {\"site\": 35, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"35\", \"IC90\": null, \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 36, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 36, \"mutant\": \"A\", \"log2 fold change IC90\": 0.008591502672335216, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.0879662448224555, \"functional effect\": -0.2626, \"times_seen\": 14.0}, {\"site\": 36, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0020562601047115457, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.08731940281174723, \"functional effect\": -0.2184, \"times_seen\": 7.0}, {\"site\": 36, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": null, \"functional effect\": -1.2668, \"times_seen\": null}, {\"site\": 36, \"mutant\": \"F\", \"log2 fold change IC90\": -0.14718837962268444, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.07896263557110135, \"functional effect\": -0.3847, \"times_seen\": 33.0}, {\"site\": 36, \"mutant\": \"I\", \"log2 fold change IC90\": 0.23706953640084807, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.10306110494595554, \"functional effect\": 0.2168, \"times_seen\": 79.0}, {\"site\": 36, \"mutant\": \"L\", \"log2 fold change IC90\": -0.019007555548503256, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.0862994262663644, \"functional effect\": 0.1621, \"times_seen\": 4.0}, {\"site\": 36, \"mutant\": \"T\", \"log2 fold change IC90\": -0.005647992846986841, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.08710228285983304, \"functional effect\": -0.0959, \"times_seen\": 9.0}, {\"site\": 36, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"36\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"*\", \"log2 fold change IC90\": 0.019370936551180613, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.0886259667868465, \"functional effect\": -2.812, \"times_seen\": 2.0}, {\"site\": 37, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0008113759221783569, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08739478219051881, \"functional effect\": -1.4704, \"times_seen\": 1.0}, {\"site\": 37, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": null, \"functional effect\": -2.2193, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0027153780928495805, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08760868528740455, \"functional effect\": -0.9055, \"times_seen\": 5.0}, {\"site\": 37, \"mutant\": \"H\", \"log2 fold change IC90\": -0.04091539818701578, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08499883840556492, \"functional effect\": -0.2204, \"times_seen\": 18.0}, {\"site\": 37, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": null, \"functional effect\": -3.1105, \"times_seen\": null}, {\"site\": 37, \"mutant\": \"L\", \"log2 fold change IC90\": 0.024605966569690375, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.0889481432517962, \"functional effect\": -2.3453, \"times_seen\": 2.0}, {\"site\": 37, \"mutant\": \"N\", \"log2 fold change IC90\": -0.013669727852667327, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.08661931694927476, \"functional effect\": -2.9696, \"times_seen\": 2.0}, {\"site\": 37, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"37\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -2.77, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"C\", \"log2 fold change IC90\": -0.07072483206551891, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08326058480083198, \"functional effect\": -2.6265, \"times_seen\": 3.0}, {\"site\": 38, \"mutant\": \"F\", \"log2 fold change IC90\": -0.017237344664846985, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08640538209361699, \"functional effect\": -0.0741, \"times_seen\": 4.0}, {\"site\": 38, \"mutant\": \"H\", \"log2 fold change IC90\": 0.00362614215181054, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08766400954552744, \"functional effect\": -1.4529, \"times_seen\": 5.0}, {\"site\": 38, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014269642809062018, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.08658330558190291, \"functional effect\": -0.5605, \"times_seen\": 3.0}, {\"site\": 38, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -1.4117, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": null, \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 38, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"38\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 39, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 39, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004381600746089333, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08717877447237571, \"functional effect\": -0.37, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"G\", \"log2 fold change IC90\": -0.008930990472763918, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08690429820964263, \"functional effect\": -0.2309, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"H\", \"log2 fold change IC90\": 0.014974213697332105, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08835628356186948, \"functional effect\": -0.2172, \"times_seen\": 4.0}, {\"site\": 39, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03844223240878388, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08980531031614808, \"functional effect\": -1.6753, \"times_seen\": 4.0}, {\"site\": 39, \"mutant\": \"N\", \"log2 fold change IC90\": -0.006379164135814201, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.0870581497957853, \"functional effect\": 0.35, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 39, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0038858546579968204, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08720873642657928, \"functional effect\": -1.1557, \"times_seen\": 1.0}, {\"site\": 39, \"mutant\": \"S\", \"log2 fold change IC90\": -0.022485266452656746, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08609164638017293, \"functional effect\": 0.3631, \"times_seen\": 36.0}, {\"site\": 39, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0019383751810179801, \"epitope\": \"all\", \"reference_site\": \"39\", \"IC90\": 0.08732653811159376, \"functional effect\": -0.0649, \"times_seen\": 20.0}, {\"site\": 40, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 40, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 40, \"mutant\": \"E\", \"log2 fold change IC90\": 0.050370557948325206, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.0905509063530405, \"functional effect\": -0.0319, \"times_seen\": 5.0}, {\"site\": 40, \"mutant\": \"G\", \"log2 fold change IC90\": 0.039840948595001945, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.08989242023804465, \"functional effect\": -0.0019, \"times_seen\": 2.0}, {\"site\": 40, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": null, \"functional effect\": -0.4397, \"times_seen\": null}, {\"site\": 40, \"mutant\": \"N\", \"log2 fold change IC90\": 3.7577826323664554, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 1.182864620824171, \"functional effect\": -0.6738, \"times_seen\": 6.0}, {\"site\": 40, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.08917519935992727, \"epitope\": \"all\", \"reference_site\": \"40\", \"IC90\": 0.09301953468639237, \"functional effect\": -2.2738, \"times_seen\": 1.0}, {\"site\": 41, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 41, \"mutant\": \"E\", \"log2 fold change IC90\": 0.017643459502194654, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08851990993106032, \"functional effect\": -0.6505, \"times_seen\": 12.0}, {\"site\": 41, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 41, \"mutant\": \"I\", \"log2 fold change IC90\": 0.018981979970368358, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08860207607841346, \"functional effect\": -0.4399, \"times_seen\": 8.0}, {\"site\": 41, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 41, \"mutant\": \"M\", \"log2 fold change IC90\": -0.014210900905820183, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08658683104747968, \"functional effect\": -0.3101, \"times_seen\": 1.0}, {\"site\": 41, \"mutant\": \"N\", \"log2 fold change IC90\": -0.043598875812704496, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08484088369237759, \"functional effect\": 0.1298, \"times_seen\": 29.0}, {\"site\": 41, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0034610969760175163, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08723441616709879, \"functional effect\": -0.2988, \"times_seen\": 2.0}, {\"site\": 41, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0591526411583541, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.09110379581984196, \"functional effect\": -0.2941, \"times_seen\": 11.0}, {\"site\": 41, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004754572357865776, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08715623956064178, \"functional effect\": -0.0335, \"times_seen\": 25.0}, {\"site\": 41, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0010946307976651215, \"epitope\": \"all\", \"reference_site\": \"41\", \"IC90\": 0.08737762501769983, \"functional effect\": -0.6873, \"times_seen\": 1.0}, {\"site\": 42, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": null, \"functional effect\": -1.9412, \"times_seen\": null}, {\"site\": 42, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": null, \"functional effect\": -3.3265, \"times_seen\": null}, {\"site\": 42, \"mutant\": \"E\", \"log2 fold change IC90\": 0.04616256941107186, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.09028717631380685, \"functional effect\": -2.0016, \"times_seen\": 2.0}, {\"site\": 42, \"mutant\": \"F\", \"log2 fold change IC90\": -0.021709007284229285, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08613798147549215, \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 42, \"mutant\": \"I\", \"log2 fold change IC90\": -0.1208784042632413, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08041586305231514, \"functional effect\": 0.3356, \"times_seen\": 25.0}, {\"site\": 42, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015400742173974281, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.086515449286525, \"functional effect\": 0.3644, \"times_seen\": 4.0}, {\"site\": 42, \"mutant\": \"M\", \"log2 fold change IC90\": -0.008082149592889, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08695544528133817, \"functional effect\": 0.0304, \"times_seen\": 5.0}, {\"site\": 42, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.058651018665648154, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08396031067754262, \"functional effect\": -1.3902, \"times_seen\": 6.0}, {\"site\": 42, \"mutant\": \"R\", \"log2 fold change IC90\": -0.010330186523103014, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.08682005503871237, \"functional effect\": -0.8912, \"times_seen\": 1.0}, {\"site\": 42, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008506417536488887, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.0869298771725012, \"functional effect\": -0.3052, \"times_seen\": 4.0}, {\"site\": 42, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"42\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": null, \"functional effect\": -3.1126, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": null, \"functional effect\": -2.939, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": null, \"functional effect\": -2.9977, \"times_seen\": null}, {\"site\": 43, \"mutant\": \"Y\", \"log2 fold change IC90\": 1.2010723569545936, \"epitope\": \"all\", \"reference_site\": \"43\", \"IC90\": 0.2010428162103805, \"functional effect\": 0.171, \"times_seen\": 8.0}, {\"site\": 44, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05454396562633334, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08419966877773447, \"functional effect\": -3.1109, \"times_seen\": 2.0}, {\"site\": 44, \"mutant\": \"I\", \"log2 fold change IC90\": -0.002403177001850104, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08729840812224406, \"functional effect\": -2.5511, \"times_seen\": 1.0}, {\"site\": 44, \"mutant\": \"K\", \"log2 fold change IC90\": 0.013069292032416205, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08823969570080883, \"functional effect\": -1.3754, \"times_seen\": 14.0}, {\"site\": 44, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0040145048913169425, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08720096006099418, \"functional effect\": -1.3611, \"times_seen\": 3.0}, {\"site\": 44, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0031488792547016823, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08763501391004642, \"functional effect\": -1.7575, \"times_seen\": 4.0}, {\"site\": 44, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 44, \"mutant\": \"S\", \"log2 fold change IC90\": 0.020464446575755545, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": 0.08869316748973304, \"functional effect\": -2.5003, \"times_seen\": 2.0}, {\"site\": 44, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"44\", \"IC90\": null, \"functional effect\": 0.0669, \"times_seen\": null}, {\"site\": 45, \"mutant\": \"A\", \"log2 fold change IC90\": 0.005280773185117852, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.08776460932471433, \"functional effect\": 0.032, \"times_seen\": 15.0}, {\"site\": 45, \"mutant\": \"F\", \"log2 fold change IC90\": -0.09551125688187857, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.08184233275249105, \"functional effect\": -0.6868, \"times_seen\": 35.0}, {\"site\": 45, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03176038550717876, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.08939033843501633, \"functional effect\": -0.596, \"times_seen\": 5.0}, {\"site\": 45, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": null, \"functional effect\": 0.1193, \"times_seen\": null}, {\"site\": 45, \"mutant\": \"P\", \"log2 fold change IC90\": -0.36380805036730945, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.06795362308870433, \"functional effect\": -1.1187, \"times_seen\": 26.0}, {\"site\": 45, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 45, \"mutant\": \"T\", \"log2 fold change IC90\": 0.2722960348180271, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.10560853715620058, \"functional effect\": -0.5499, \"times_seen\": 36.0}, {\"site\": 45, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03296047736735203, \"epitope\": \"all\", \"reference_site\": \"45\", \"IC90\": 0.0854688106368029, \"functional effect\": -0.2105, \"times_seen\": 20.0}, {\"site\": 46, \"mutant\": \"A\", \"log2 fold change IC90\": -2.5149226690987296, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.015298984077995584, \"functional effect\": 0.0387, \"times_seen\": 4.0}, {\"site\": 46, \"mutant\": \"C\", \"log2 fold change IC90\": -0.017443443229768568, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.0863930393927623, \"functional effect\": -2.7094, \"times_seen\": 1.0}, {\"site\": 46, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": null, \"functional effect\": -0.3882, \"times_seen\": null}, {\"site\": 46, \"mutant\": \"L\", \"log2 fold change IC90\": 0.012966058650077463, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08823338185340397, \"functional effect\": -0.1556, \"times_seen\": 4.0}, {\"site\": 46, \"mutant\": \"P\", \"log2 fold change IC90\": -0.10295440254922669, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08142117950318468, \"functional effect\": -2.2301, \"times_seen\": 12.0}, {\"site\": 46, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013717731374875171, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08661643486885473, \"functional effect\": -0.9944, \"times_seen\": 4.0}, {\"site\": 46, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 46, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006544776920176808, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08704815661312001, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 46, \"mutant\": \"W\", \"log2 fold change IC90\": 0.12093404550850037, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.0950899300709771, \"functional effect\": -2.5774, \"times_seen\": 17.0}, {\"site\": 46, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.011820149765090122, \"epitope\": \"all\", \"reference_site\": \"46\", \"IC90\": 0.08816332735816687, \"functional effect\": 0.0297, \"times_seen\": 5.0}, {\"site\": 47, \"mutant\": \"A\", \"log2 fold change IC90\": 0.03642134068287968, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08967960131208136, \"functional effect\": 0.1629, \"times_seen\": 6.0}, {\"site\": 47, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": null, \"functional effect\": -3.0776, \"times_seen\": null}, {\"site\": 47, \"mutant\": \"F\", \"log2 fold change IC90\": -0.001254281380219465, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08736795622664376, \"functional effect\": -0.5387, \"times_seen\": 11.0}, {\"site\": 47, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": null, \"functional effect\": -1.3525, \"times_seen\": null}, {\"site\": 47, \"mutant\": \"I\", \"log2 fold change IC90\": 0.2964139559455463, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.10738886311609362, \"functional effect\": -0.4671, \"times_seen\": 2.0}, {\"site\": 47, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07963186973135913, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.0827481268285411, \"functional effect\": -0.1979, \"times_seen\": 30.0}, {\"site\": 47, \"mutant\": \"M\", \"log2 fold change IC90\": -0.017231671109022403, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08640572189288773, \"functional effect\": 0.3864, \"times_seen\": 5.0}, {\"site\": 47, \"mutant\": \"R\", \"log2 fold change IC90\": -0.026144230495272005, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.08587357734441689, \"functional effect\": 0.1746, \"times_seen\": 7.0}, {\"site\": 47, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004668527406686595, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.0871614378720017, \"functional effect\": -0.2582, \"times_seen\": 2.0}, {\"site\": 47, \"mutant\": \"T\", \"log2 fold change IC90\": -0.8819709945307972, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.047449323852958754, \"functional effect\": -0.0317, \"times_seen\": 3.0}, {\"site\": 47, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"47\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 48, \"mutant\": \"F\", \"log2 fold change IC90\": -0.008567687848180214, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.0869261853960552, \"functional effect\": -0.8417, \"times_seen\": 2.0}, {\"site\": 48, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 48, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0005572245746128068, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08747772785103149, \"functional effect\": -0.2817, \"times_seen\": 3.0}, {\"site\": 48, \"mutant\": \"P\", \"log2 fold change IC90\": -0.08459887690977337, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08246372588982029, \"functional effect\": -1.8053, \"times_seen\": 10.0}, {\"site\": 48, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": null, \"functional effect\": -2.8194, \"times_seen\": null}, {\"site\": 48, \"mutant\": \"R\", \"log2 fold change IC90\": -0.010492796330880728, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08681026988213747, \"functional effect\": -0.17, \"times_seen\": 2.0}, {\"site\": 48, \"mutant\": \"T\", \"log2 fold change IC90\": 0.015601147912309906, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.0883946878076032, \"functional effect\": -0.3694, \"times_seen\": 2.0}, {\"site\": 48, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005290417553570285, \"epitope\": \"all\", \"reference_site\": \"48\", \"IC90\": 0.08712387403713964, \"functional effect\": -0.6601, \"times_seen\": 2.0}, {\"site\": 49, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0017672235995792576, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08755112684565854, \"functional effect\": -0.2204, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"C\", \"log2 fold change IC90\": 0.10190560121234866, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.09384397508026954, \"functional effect\": 0.2969, \"times_seen\": 21.0}, {\"site\": 49, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": null, \"functional effect\": -1.9489, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"I\", \"log2 fold change IC90\": -0.017621134353686414, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08638239935415837, \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 49, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": null, \"functional effect\": -1.1338, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"L\", \"log2 fold change IC90\": 0.014738099145615174, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08834182416704935, \"functional effect\": -0.0998, \"times_seen\": 20.0}, {\"site\": 49, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005111172740600987, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08713469924428692, \"functional effect\": -2.7292, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02645601781986013, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08906227976408045, \"functional effect\": -2.5739, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.1437519395893819, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.09660584388583675, \"functional effect\": 0.0067, \"times_seen\": 39.0}, {\"site\": 49, \"mutant\": \"R\", \"log2 fold change IC90\": -0.061559875665666404, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08379119490389236, \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 49, \"mutant\": \"S\", \"log2 fold change IC90\": 0.07820386557551563, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.0923148274227822, \"functional effect\": -1.4669, \"times_seen\": 3.0}, {\"site\": 49, \"mutant\": \"T\", \"log2 fold change IC90\": -0.01038077833227932, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08681701052374663, \"functional effect\": -0.026, \"times_seen\": 3.0}, {\"site\": 49, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": null, \"functional effect\": -0.3197, \"times_seen\": null}, {\"site\": 49, \"mutant\": \"W\", \"log2 fold change IC90\": 0.01824140940182843, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08855660614214332, \"functional effect\": 0.2159, \"times_seen\": 1.0}, {\"site\": 49, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.014728986504740575, \"epitope\": \"all\", \"reference_site\": \"49\", \"IC90\": 0.08655574247006273, \"functional effect\": -0.1723, \"times_seen\": 20.0}, {\"site\": 50, \"mutant\": \"A\", \"log2 fold change IC90\": -0.011346720667114937, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.0867589024996384, \"functional effect\": 0.0423, \"times_seen\": 2.0}, {\"site\": 50, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0040505687030890376, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08719878027967166, \"functional effect\": -0.5661, \"times_seen\": 2.0}, {\"site\": 50, \"mutant\": \"F\", \"log2 fold change IC90\": -0.028997554004070236, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08570390672954965, \"functional effect\": -0.3996, \"times_seen\": 10.0}, {\"site\": 50, \"mutant\": \"G\", \"log2 fold change IC90\": 0.06940470147137565, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.0917535021352233, \"functional effect\": -0.0512, \"times_seen\": 20.0}, {\"site\": 50, \"mutant\": \"I\", \"log2 fold change IC90\": -0.002974110421802006, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08726386740752701, \"functional effect\": 0.0653, \"times_seen\": 2.0}, {\"site\": 50, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01544307170641103, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08651291090891322, \"functional effect\": -0.4275, \"times_seen\": 5.0}, {\"site\": 50, \"mutant\": \"N\", \"log2 fold change IC90\": 0.7547909829255638, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.1475517888794298, \"functional effect\": -0.1203, \"times_seen\": 45.0}, {\"site\": 50, \"mutant\": \"P\", \"log2 fold change IC90\": 0.05903769457040226, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.09109653742287473, \"functional effect\": -0.1371, \"times_seen\": 33.0}, {\"site\": 50, \"mutant\": \"R\", \"log2 fold change IC90\": -0.007110039751389395, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08701405692621977, \"functional effect\": -1.2814, \"times_seen\": 7.0}, {\"site\": 50, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 50, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006875293455493076, \"epitope\": \"all\", \"reference_site\": \"50\", \"IC90\": 0.08702821646020262, \"functional effect\": 0.0492, \"times_seen\": 9.0}, {\"site\": 51, \"mutant\": \"A\", \"log2 fold change IC90\": 0.06955657887704143, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.09176316184639104, \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 51, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009819946924991526, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08685076621696072, \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 51, \"mutant\": \"I\", \"log2 fold change IC90\": -0.028086830373577485, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08575802573045073, \"functional effect\": -0.0949, \"times_seen\": 24.0}, {\"site\": 51, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": null, \"functional effect\": -3.205, \"times_seen\": null}, {\"site\": 51, \"mutant\": \"N\", \"log2 fold change IC90\": 0.028104131231451494, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08916408132842549, \"functional effect\": 0.3228, \"times_seen\": 6.0}, {\"site\": 51, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03742659860766761, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.08520463571640068, \"functional effect\": 0.0009, \"times_seen\": 3.0}, {\"site\": 51, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"51\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 52, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": null, \"functional effect\": -2.8375, \"times_seen\": null}, {\"site\": 52, \"mutant\": \"E\", \"log2 fold change IC90\": 0.10231493119788133, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.09387060482653758, \"functional effect\": -1.0619, \"times_seen\": 22.0}, {\"site\": 52, \"mutant\": \"H\", \"log2 fold change IC90\": -1.0825073596973902, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.041291681332775304, \"functional effect\": 0.3659, \"times_seen\": 64.0}, {\"site\": 52, \"mutant\": \"K\", \"log2 fold change IC90\": -0.014318427378163969, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08658037782675058, \"functional effect\": 0.042, \"times_seen\": 6.0}, {\"site\": 52, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07155946623430694, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08321243045812508, \"functional effect\": -0.0164, \"times_seen\": 29.0}, {\"site\": 52, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02522048650058652, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08898603902902111, \"functional effect\": 0.0047, \"times_seen\": 16.0}, {\"site\": 52, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 52, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08931242811907364, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08219474131414135, \"functional effect\": 0.1996, \"times_seen\": 23.0}, {\"site\": 52, \"mutant\": \"S\", \"log2 fold change IC90\": 0.031412333144375484, \"epitope\": \"all\", \"reference_site\": \"52\", \"IC90\": 0.08936877548168724, \"functional effect\": 0.3851, \"times_seen\": 3.0}, {\"site\": 53, \"mutant\": \"C\", \"log2 fold change IC90\": -0.013373740079062132, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.08663708985916935, \"functional effect\": -0.3682, \"times_seen\": 13.0}, {\"site\": 53, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 53, \"mutant\": \"E\", \"log2 fold change IC90\": 0.11914110194455052, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.0949718282016526, \"functional effect\": 0.1243, \"times_seen\": 4.0}, {\"site\": 53, \"mutant\": \"G\", \"log2 fold change IC90\": 0.07690719216343392, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.0922318934681435, \"functional effect\": 0.0635, \"times_seen\": 34.0}, {\"site\": 53, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": null, \"functional effect\": -2.9837, \"times_seen\": null}, {\"site\": 53, \"mutant\": \"N\", \"log2 fold change IC90\": -0.23058974910725616, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.07452728865697861, \"functional effect\": 0.0979, \"times_seen\": 173.0}, {\"site\": 53, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008373287224268293, \"epitope\": \"all\", \"reference_site\": \"53\", \"IC90\": 0.08795294045712597, \"functional effect\": -2.8725, \"times_seen\": 5.0}, {\"site\": 54, \"mutant\": \"F\", \"log2 fold change IC90\": -0.022285445425545343, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08610357136232188, \"functional effect\": -0.2798, \"times_seen\": 11.0}, {\"site\": 54, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 54, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0197831660239169, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.0862530431099141, \"functional effect\": 0.0382, \"times_seen\": 7.0}, {\"site\": 54, \"mutant\": \"P\", \"log2 fold change IC90\": 0.5658826102507314, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.12944264914458078, \"functional effect\": -2.1354, \"times_seen\": 14.0}, {\"site\": 54, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": null, \"functional effect\": -0.3841, \"times_seen\": null}, {\"site\": 54, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0024234076071977728, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08729718396383955, \"functional effect\": -1.0069, \"times_seen\": 2.0}, {\"site\": 54, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": null, \"functional effect\": -0.3237, \"times_seen\": null}, {\"site\": 54, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04259032099528415, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08490021473279397, \"functional effect\": -0.7697, \"times_seen\": 12.0}, {\"site\": 54, \"mutant\": \"W\", \"log2 fold change IC90\": -0.04255191764945782, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08490247473619757, \"functional effect\": 0.1398, \"times_seen\": 6.0}, {\"site\": 54, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03539678211540822, \"epitope\": \"all\", \"reference_site\": \"54\", \"IC90\": 0.08961593616937655, \"functional effect\": -0.5728, \"times_seen\": 2.0}, {\"site\": 55, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": null, \"functional effect\": -2.1941, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"L\", \"log2 fold change IC90\": -0.008846800620425931, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": 0.08690936974126234, \"functional effect\": -0.7282, \"times_seen\": 2.0}, {\"site\": 55, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": null, \"functional effect\": -2.7433, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 55, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07261001429148876, \"epitope\": \"all\", \"reference_site\": \"55\", \"IC90\": 0.08315185851884031, \"functional effect\": 0.2628, \"times_seen\": 20.0}, {\"site\": 56, \"mutant\": \"F\", \"log2 fold change IC90\": 0.013003658464124894, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08823568143986421, \"functional effect\": -1.7867, \"times_seen\": 6.0}, {\"site\": 56, \"mutant\": \"I\", \"log2 fold change IC90\": -0.000334270213259112, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08742368881576447, \"functional effect\": -0.2693, \"times_seen\": 5.0}, {\"site\": 56, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 56, \"mutant\": \"M\", \"log2 fold change IC90\": -0.07517474176369514, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08300416798080962, \"functional effect\": 0.1187, \"times_seen\": 5.0}, {\"site\": 56, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0011715314117915323, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.08751498424092109, \"functional effect\": -2.2717, \"times_seen\": 4.0}, {\"site\": 56, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.006196989764804493, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.0870691436403665, \"functional effect\": -0.3305, \"times_seen\": 1.0}, {\"site\": 56, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": null, \"functional effect\": -2.7355, \"times_seen\": null}, {\"site\": 56, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0006485752600452006, \"epitope\": \"all\", \"reference_site\": \"56\", \"IC90\": 0.0874832670697685, \"functional effect\": -0.0474, \"times_seen\": 13.0}, {\"site\": 57, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": null, \"functional effect\": -0.9319, \"times_seen\": null}, {\"site\": 57, \"mutant\": \"L\", \"log2 fold change IC90\": -0.003149757979916182, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.08725324371245954, \"functional effect\": -2.8649, \"times_seen\": 1.0}, {\"site\": 57, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 57, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": null, \"functional effect\": -2.3902, \"times_seen\": null}, {\"site\": 57, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01260274458199127, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.08821116482766717, \"functional effect\": -1.402, \"times_seen\": 12.0}, {\"site\": 57, \"mutant\": \"T\", \"log2 fold change IC90\": 0.019551659856398906, \"epitope\": \"all\", \"reference_site\": \"57\", \"IC90\": 0.08863706946650331, \"functional effect\": -1.9551, \"times_seen\": 2.0}, {\"site\": 58, \"mutant\": \"C\", \"log2 fold change IC90\": 0.05929169584875609, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.09111257731579737, \"functional effect\": -2.9909, \"times_seen\": 3.0}, {\"site\": 58, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 58, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": null, \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 58, \"mutant\": \"L\", \"log2 fold change IC90\": -0.004050111205032914, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.08719880793158538, \"functional effect\": -0.6816, \"times_seen\": 10.0}, {\"site\": 58, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": null, \"functional effect\": -2.9906, \"times_seen\": null}, {\"site\": 58, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013199372804145378, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.08664756163995935, \"functional effect\": -1.1986, \"times_seen\": 4.0}, {\"site\": 58, \"mutant\": \"V\", \"log2 fold change IC90\": 0.05494417367444025, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": 0.0908384253302405, \"functional effect\": -1.701, \"times_seen\": 1.0}, {\"site\": 58, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"58\", \"IC90\": null, \"functional effect\": 0.0307, \"times_seen\": null}, {\"site\": 59, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006368534883542463, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.08705879121092788, \"functional effect\": -0.1, \"times_seen\": 1.0}, {\"site\": 59, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 59, \"mutant\": \"I\", \"log2 fold change IC90\": 0.019415028646534962, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.0886286754426487, \"functional effect\": -2.142, \"times_seen\": 1.0}, {\"site\": 59, \"mutant\": \"L\", \"log2 fold change IC90\": -0.14681751497551193, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.07898293661425955, \"functional effect\": -0.1372, \"times_seen\": 28.0}, {\"site\": 59, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04693922966739195, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.08464467400598925, \"functional effect\": 0.2057, \"times_seen\": 24.0}, {\"site\": 59, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02904405457261679, \"epitope\": \"all\", \"reference_site\": \"59\", \"IC90\": 0.08570114438820164, \"functional effect\": -0.0095, \"times_seen\": 35.0}, {\"site\": 60, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": null, \"functional effect\": -2.3603, \"times_seen\": null}, {\"site\": 60, \"mutant\": \"A\", \"log2 fold change IC90\": 0.006327194295766483, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08782829018021696, \"functional effect\": -0.2894, \"times_seen\": 15.0}, {\"site\": 60, \"mutant\": \"C\", \"log2 fold change IC90\": 0.006461363110434949, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08783645847996908, \"functional effect\": -0.4102, \"times_seen\": 18.0}, {\"site\": 60, \"mutant\": \"F\", \"log2 fold change IC90\": 0.01199033324084381, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08817372791132766, \"functional effect\": -1.6135, \"times_seen\": 34.0}, {\"site\": 60, \"mutant\": \"G\", \"log2 fold change IC90\": -0.009103878727714346, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08689388448268313, \"functional effect\": -0.4363, \"times_seen\": 12.0}, {\"site\": 60, \"mutant\": \"I\", \"log2 fold change IC90\": -0.00748182691555376, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08699163601225858, \"functional effect\": -0.5157, \"times_seen\": 2.0}, {\"site\": 60, \"mutant\": \"L\", \"log2 fold change IC90\": -0.007243854133541406, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.0870059864803134, \"functional effect\": -2.112, \"times_seen\": 2.0}, {\"site\": 60, \"mutant\": \"N\", \"log2 fold change IC90\": 0.027662250746718634, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.0891367756032929, \"functional effect\": -0.3375, \"times_seen\": 15.0}, {\"site\": 60, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005126760230046522, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08713375780910554, \"functional effect\": -2.9879, \"times_seen\": 1.0}, {\"site\": 60, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03471862405721398, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08536471713274224, \"functional effect\": -1.0799, \"times_seen\": 3.0}, {\"site\": 60, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 60, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04195295492644916, \"epitope\": \"all\", \"reference_site\": \"60\", \"IC90\": 0.08493773095727483, \"functional effect\": -0.0547, \"times_seen\": 21.0}, {\"site\": 61, \"mutant\": \"D\", \"log2 fold change IC90\": 0.01644007946321065, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08844610453525438, \"functional effect\": -0.1119, \"times_seen\": 8.0}, {\"site\": 61, \"mutant\": \"H\", \"log2 fold change IC90\": -0.019108068007945817, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08629341400100035, \"functional effect\": -0.192, \"times_seen\": 7.0}, {\"site\": 61, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0008531949055637833, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08739224893999006, \"functional effect\": -0.1077, \"times_seen\": 29.0}, {\"site\": 61, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 61, \"mutant\": \"S\", \"log2 fold change IC90\": -0.1337755168034767, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.07970018134786669, \"functional effect\": -0.2256, \"times_seen\": 16.0}, {\"site\": 61, \"mutant\": \"T\", \"log2 fold change IC90\": 0.011183826384538333, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08812445010777463, \"functional effect\": -0.0966, \"times_seen\": 16.0}, {\"site\": 61, \"mutant\": \"W\", \"log2 fold change IC90\": 0.007306442587281762, \"epitope\": \"all\", \"reference_site\": \"61\", \"IC90\": 0.08788792502751681, \"functional effect\": -1.2228, \"times_seen\": 5.0}, {\"site\": 62, \"mutant\": \"-\", \"log2 fold change IC90\": 0.09422195891975661, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.09334550051327832, \"functional effect\": -1.2254, \"times_seen\": 6.0}, {\"site\": 62, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0050049343559167465, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08774783060695993, \"functional effect\": -0.5063, \"times_seen\": 18.0}, {\"site\": 62, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004127310574158074, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08719414200242849, \"functional effect\": -2.1029, \"times_seen\": 2.0}, {\"site\": 62, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0015315166333734198, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08735116879086101, \"functional effect\": -2.957, \"times_seen\": 1.0}, {\"site\": 62, \"mutant\": \"F\", \"log2 fold change IC90\": -0.020407827451303318, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08621570515222642, \"functional effect\": -1.0437, \"times_seen\": 30.0}, {\"site\": 62, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0003222362508000382, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.08746348050836303, \"functional effect\": -0.8009, \"times_seen\": 11.0}, {\"site\": 62, \"mutant\": \"I\", \"log2 fold change IC90\": 0.9385606795638802, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.16759639399926396, \"functional effect\": 0.0795, \"times_seen\": 54.0}, {\"site\": 62, \"mutant\": \"L\", \"log2 fold change IC90\": 0.06169341433682637, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.0912643827921162, \"functional effect\": -0.0591, \"times_seen\": 84.0}, {\"site\": 62, \"mutant\": \"M\", \"log2 fold change IC90\": 0.2635609925822638, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.10497104417759318, \"functional effect\": 0.0445, \"times_seen\": 21.0}, {\"site\": 62, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"62\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 63, \"mutant\": \"-\", \"log2 fold change IC90\": -0.006269792704245439, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.0870647499677784, \"functional effect\": -0.1452, \"times_seen\": 15.0}, {\"site\": 63, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00898478867139837, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08690105760272654, \"functional effect\": -0.1278, \"times_seen\": 16.0}, {\"site\": 63, \"mutant\": \"I\", \"log2 fold change IC90\": -0.09088083469979777, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08210543295656844, \"functional effect\": -0.3034, \"times_seen\": 50.0}, {\"site\": 63, \"mutant\": \"L\", \"log2 fold change IC90\": -0.023784733169104545, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08601413667946166, \"functional effect\": -0.7167, \"times_seen\": 5.0}, {\"site\": 63, \"mutant\": \"N\", \"log2 fold change IC90\": 0.11857556700158783, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.09493460664048495, \"functional effect\": -0.1516, \"times_seen\": 24.0}, {\"site\": 63, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 63, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.04027774603121156, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.08991964062917389, \"functional effect\": -0.2228, \"times_seen\": 5.0}, {\"site\": 63, \"mutant\": \"S\", \"log2 fold change IC90\": 0.11370611167850038, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.09461471883692472, \"functional effect\": -0.1262, \"times_seen\": 17.0}, {\"site\": 63, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"63\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 64, \"mutant\": \"*\", \"log2 fold change IC90\": -0.013873402115625225, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08660708922285185, \"functional effect\": -2.6819, \"times_seen\": 2.0}, {\"site\": 64, \"mutant\": \"-\", \"log2 fold change IC90\": -2.882987559160861, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.011853975366079746, \"functional effect\": 0.1828, \"times_seen\": 20.0}, {\"site\": 64, \"mutant\": \"C\", \"log2 fold change IC90\": 0.01856323225751496, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08857636272133153, \"functional effect\": 0.0504, \"times_seen\": 94.0}, {\"site\": 64, \"mutant\": \"F\", \"log2 fold change IC90\": 0.10465736230150229, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.09402314158815848, \"functional effect\": -0.0032, \"times_seen\": 19.0}, {\"site\": 64, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0337281976457235, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08542334109421627, \"functional effect\": 0.0158, \"times_seen\": 15.0}, {\"site\": 64, \"mutant\": \"K\", \"log2 fold change IC90\": 0.05683698407342672, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.09095768321414369, \"functional effect\": -0.1005, \"times_seen\": 23.0}, {\"site\": 64, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00423326239226734, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08770090840029655, \"functional effect\": -0.0708, \"times_seen\": 101.0}, {\"site\": 64, \"mutant\": \"R\", \"log2 fold change IC90\": -0.28918188969372155, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.0715611530787664, \"functional effect\": -0.1623, \"times_seen\": 122.0}, {\"site\": 64, \"mutant\": \"S\", \"log2 fold change IC90\": 0.006844090223152591, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.08785976337303554, \"functional effect\": -0.0457, \"times_seen\": 20.0}, {\"site\": 64, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"64\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 65, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": null, \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 65, \"mutant\": \"-\", \"log2 fold change IC90\": -0.04886921282416493, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08453151525176632, \"functional effect\": 0.2061, \"times_seen\": 17.0}, {\"site\": 65, \"mutant\": \"C\", \"log2 fold change IC90\": -1.1812656503411414, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.03855967450508701, \"functional effect\": -0.2315, \"times_seen\": 24.0}, {\"site\": 65, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 65, \"mutant\": \"I\", \"log2 fold change IC90\": -0.009911830255949085, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08684523498315644, \"functional effect\": -0.1169, \"times_seen\": 1.0}, {\"site\": 65, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02772586422621727, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08914070604271375, \"functional effect\": 0.0363, \"times_seen\": 31.0}, {\"site\": 65, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03332687203199032, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08948745168915039, \"functional effect\": -0.5773, \"times_seen\": 14.0}, {\"site\": 65, \"mutant\": \"V\", \"log2 fold change IC90\": 0.009268664855768417, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08800754349929361, \"functional effect\": 0.0132, \"times_seen\": 9.0}, {\"site\": 65, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01868043943488843, \"epitope\": \"all\", \"reference_site\": \"65\", \"IC90\": 0.08631899598331162, \"functional effect\": -0.1808, \"times_seen\": 35.0}, {\"site\": 66, \"mutant\": \"-\", \"log2 fold change IC90\": 0.1339112857305883, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.09594913560670097, \"functional effect\": -0.1132, \"times_seen\": 30.0}, {\"site\": 66, \"mutant\": \"D\", \"log2 fold change IC90\": 0.03484988053346848, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08958197070377294, \"functional effect\": 0.0423, \"times_seen\": 15.0}, {\"site\": 66, \"mutant\": \"F\", \"log2 fold change IC90\": 0.05684129304336201, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.09095795488244263, \"functional effect\": 0.113, \"times_seen\": 26.0}, {\"site\": 66, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 66, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 66, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0804548147901524, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08270093893241644, \"functional effect\": -0.0595, \"times_seen\": 24.0}, {\"site\": 66, \"mutant\": \"N\", \"log2 fold change IC90\": -0.2531674019437336, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.07337004254595353, \"functional effect\": 0.1133, \"times_seen\": 44.0}, {\"site\": 66, \"mutant\": \"P\", \"log2 fold change IC90\": -0.007672115532600821, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08698016274451857, \"functional effect\": -0.1817, \"times_seen\": 13.0}, {\"site\": 66, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.049699697469074496, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.08448286884940455, \"functional effect\": 0.0272, \"times_seen\": 15.0}, {\"site\": 66, \"mutant\": \"R\", \"log2 fold change IC90\": -0.3993526008255223, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.06629986454735304, \"functional effect\": -0.0116, \"times_seen\": 39.0}, {\"site\": 66, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.20042590973488045, \"epitope\": \"all\", \"reference_site\": \"66\", \"IC90\": 0.07610190742195408, \"functional effect\": 0.1116, \"times_seen\": 117.0}, {\"site\": 67, \"mutant\": \"*\", \"log2 fold change IC90\": -0.01294209676385408, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08666301489150896, \"functional effect\": -2.6734, \"times_seen\": 5.0}, {\"site\": 67, \"mutant\": \"-\", \"log2 fold change IC90\": -0.11728382736606649, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08061647468716511, \"functional effect\": -0.1529, \"times_seen\": 19.0}, {\"site\": 67, \"mutant\": \"A\", \"log2 fold change IC90\": -0.12756586819276033, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08004396623120946, \"functional effect\": -0.1023, \"times_seen\": 220.0}, {\"site\": 67, \"mutant\": \"C\", \"log2 fold change IC90\": 0.03485102070597526, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08958204150109154, \"functional effect\": -0.3216, \"times_seen\": 99.0}, {\"site\": 67, \"mutant\": \"D\", \"log2 fold change IC90\": -3.7536055289480026, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.006483087702341585, \"functional effect\": -0.033, \"times_seen\": 115.0}, {\"site\": 67, \"mutant\": \"E\", \"log2 fold change IC90\": 0.08004873451985924, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.09243295196907607, \"functional effect\": -0.0541, \"times_seen\": 110.0}, {\"site\": 67, \"mutant\": \"F\", \"log2 fold change IC90\": -1.4372114748232006, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.03229133415551242, \"functional effect\": -0.0415, \"times_seen\": 89.0}, {\"site\": 67, \"mutant\": \"G\", \"log2 fold change IC90\": 0.011921985278018665, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08816955076248073, \"functional effect\": -0.0284, \"times_seen\": 116.0}, {\"site\": 67, \"mutant\": \"H\", \"log2 fold change IC90\": 0.01789703579115155, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.0885354700615142, \"functional effect\": -0.0483, \"times_seen\": 63.0}, {\"site\": 67, \"mutant\": \"I\", \"log2 fold change IC90\": 0.8148307795550515, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.15382193096503466, \"functional effect\": 0.0065, \"times_seen\": 106.0}, {\"site\": 67, \"mutant\": \"K\", \"log2 fold change IC90\": -0.1541668132372888, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07858160913160624, \"functional effect\": -0.3331, \"times_seen\": 58.0}, {\"site\": 67, \"mutant\": \"L\", \"log2 fold change IC90\": -0.14852406378865174, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07888956376376204, \"functional effect\": 0.0207, \"times_seen\": 188.0}, {\"site\": 67, \"mutant\": \"M\", \"log2 fold change IC90\": 0.44072094967954084, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.1186861325601059, \"functional effect\": 0.0777, \"times_seen\": 82.0}, {\"site\": 67, \"mutant\": \"N\", \"log2 fold change IC90\": 0.027128690930168283, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08910381575611517, \"functional effect\": -0.0498, \"times_seen\": 68.0}, {\"site\": 67, \"mutant\": \"P\", \"log2 fold change IC90\": 0.15407589761989773, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.09729963690727823, \"functional effect\": -0.0876, \"times_seen\": 152.0}, {\"site\": 67, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010882545302076108, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08810604881235887, \"functional effect\": -0.0541, \"times_seen\": 57.0}, {\"site\": 67, \"mutant\": \"R\", \"log2 fold change IC90\": 0.05265548997567401, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.09069443398176089, \"functional effect\": -0.1584, \"times_seen\": 122.0}, {\"site\": 67, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013465191278054423, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.08663159818254511, \"functional effect\": -0.0764, \"times_seen\": 270.0}, {\"site\": 67, \"mutant\": \"T\", \"log2 fold change IC90\": -0.27977090294421847, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07202948657163734, \"functional effect\": 0.0328, \"times_seen\": 193.0}, {\"site\": 67, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 67, \"mutant\": \"W\", \"log2 fold change IC90\": -0.13862208212265065, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07943288712988036, \"functional effect\": 0.0267, \"times_seen\": 63.0}, {\"site\": 67, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.1492679192671964, \"epitope\": \"all\", \"reference_site\": \"67\", \"IC90\": 0.07884889868432933, \"functional effect\": -0.0282, \"times_seen\": 63.0}, {\"site\": 68, \"mutant\": \"-\", \"log2 fold change IC90\": -0.08890923212293213, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08221771583132155, \"functional effect\": -0.0795, \"times_seen\": 15.0}, {\"site\": 68, \"mutant\": \"C\", \"log2 fold change IC90\": -0.029196905467903704, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08569206499001542, \"functional effect\": 0.008, \"times_seen\": 11.0}, {\"site\": 68, \"mutant\": \"F\", \"log2 fold change IC90\": -0.023592356712252797, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08602560701634604, \"functional effect\": -0.1689, \"times_seen\": 16.0}, {\"site\": 68, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 68, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01766822235621321, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08637957997227662, \"functional effect\": -0.2093, \"times_seen\": 7.0}, {\"site\": 68, \"mutant\": \"L\", \"log2 fold change IC90\": 0.019299532057709456, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08862158045745303, \"functional effect\": -0.2424, \"times_seen\": 25.0}, {\"site\": 68, \"mutant\": \"M\", \"log2 fold change IC90\": 0.06513332031582253, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.091482249672509, \"functional effect\": -0.0642, \"times_seen\": 37.0}, {\"site\": 68, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0444347688763967, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08479174138347262, \"functional effect\": -0.1163, \"times_seen\": 16.0}, {\"site\": 68, \"mutant\": \"R\", \"log2 fold change IC90\": -0.024971010779781602, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08594343933693963, \"functional effect\": 0.094, \"times_seen\": 22.0}, {\"site\": 68, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": null, \"functional effect\": -0.4954, \"times_seen\": null}, {\"site\": 68, \"mutant\": \"T\", \"log2 fold change IC90\": -0.31508768952121313, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.07028763117316952, \"functional effect\": -0.0391, \"times_seen\": 106.0}, {\"site\": 68, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0001395601702290461, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.0874354885506123, \"functional effect\": -0.0412, \"times_seen\": 23.0}, {\"site\": 68, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007857843760097223, \"epitope\": \"all\", \"reference_site\": \"68\", \"IC90\": 0.08696896590028695, \"functional effect\": 0.0902, \"times_seen\": 19.0}, {\"site\": 69, \"mutant\": \"-\", \"log2 fold change IC90\": 0.26418467733720064, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.10501643352975083, \"functional effect\": 0.0673, \"times_seen\": 21.0}, {\"site\": 69, \"mutant\": \"A\", \"log2 fold change IC90\": 0.6631714764652162, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.13847273161741758, \"functional effect\": 0.1456, \"times_seen\": 56.0}, {\"site\": 69, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": null, \"functional effect\": -0.1804, \"times_seen\": null}, {\"site\": 69, \"mutant\": \"E\", \"log2 fold change IC90\": 0.012423169099708555, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08820018566976928, \"functional effect\": 0.3574, \"times_seen\": 8.0}, {\"site\": 69, \"mutant\": \"F\", \"log2 fold change IC90\": 0.027146075533780786, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08910488947149257, \"functional effect\": 0.0848, \"times_seen\": 63.0}, {\"site\": 69, \"mutant\": \"L\", \"log2 fold change IC90\": 0.014126231608992495, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08830436508387955, \"functional effect\": -0.0858, \"times_seen\": 12.0}, {\"site\": 69, \"mutant\": \"P\", \"log2 fold change IC90\": 0.03699172661096822, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08971506417447943, \"functional effect\": 0.0396, \"times_seen\": 69.0}, {\"site\": 69, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 69, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02750814478434439, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08579243139943231, \"functional effect\": 0.0112, \"times_seen\": 15.0}, {\"site\": 69, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0010233146699326094, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.08738194442527424, \"functional effect\": 0.04, \"times_seen\": 12.0}, {\"site\": 69, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.19230882734382354, \"epitope\": \"all\", \"reference_site\": \"71\", \"IC90\": 0.07653128886657896, \"functional effect\": 0.1375, \"times_seen\": 93.0}, {\"site\": 70, \"mutant\": \"-\", \"log2 fold change IC90\": -0.05212129312470311, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08434118142443404, \"functional effect\": -0.1119, \"times_seen\": 16.0}, {\"site\": 70, \"mutant\": \"A\", \"log2 fold change IC90\": 0.33117005879599265, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.11000739337295702, \"functional effect\": 0.0703, \"times_seen\": 41.0}, {\"site\": 70, \"mutant\": \"C\", \"log2 fold change IC90\": -0.009131357746663146, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08689222943023554, \"functional effect\": 0.105, \"times_seen\": 3.0}, {\"site\": 70, \"mutant\": \"D\", \"log2 fold change IC90\": 0.006221651435126836, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.087821865184173, \"functional effect\": 0.0347, \"times_seen\": 25.0}, {\"site\": 70, \"mutant\": \"E\", \"log2 fold change IC90\": -0.008682860708286383, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.0869192462041277, \"functional effect\": -0.0627, \"times_seen\": 22.0}, {\"site\": 70, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 70, \"mutant\": \"R\", \"log2 fold change IC90\": -0.014850048377123956, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08654847956257691, \"functional effect\": -0.3069, \"times_seen\": 24.0}, {\"site\": 70, \"mutant\": \"S\", \"log2 fold change IC90\": 0.05095188673048115, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.09058740086751829, \"functional effect\": 0.021, \"times_seen\": 9.0}, {\"site\": 70, \"mutant\": \"V\", \"log2 fold change IC90\": 0.013507105408354718, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.08826647778603995, \"functional effect\": -0.0736, \"times_seen\": 35.0}, {\"site\": 70, \"mutant\": \"W\", \"log2 fold change IC90\": -0.030178146762751736, \"epitope\": \"all\", \"reference_site\": \"72\", \"IC90\": 0.0856338018075229, \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 71, \"mutant\": \"-\", \"log2 fold change IC90\": 0.020237914522724484, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08867924197711734, \"functional effect\": 0.1346, \"times_seen\": 16.0}, {\"site\": 71, \"mutant\": \"A\", \"log2 fold change IC90\": -0.018515047440721723, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08632889224609841, \"functional effect\": -0.126, \"times_seen\": 6.0}, {\"site\": 71, \"mutant\": \"I\", \"log2 fold change IC90\": 0.006868375057685235, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08786124232576853, \"functional effect\": 0.0507, \"times_seen\": 48.0}, {\"site\": 71, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08618543081677742, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08237308910966686, \"functional effect\": 0.0925, \"times_seen\": 16.0}, {\"site\": 71, \"mutant\": \"N\", \"log2 fold change IC90\": 0.046677015831544766, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.09031937729578868, \"functional effect\": -0.0987, \"times_seen\": 21.0}, {\"site\": 71, \"mutant\": \"P\", \"log2 fold change IC90\": -0.024516480679585423, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.08597052062112785, \"functional effect\": 0.0129, \"times_seen\": 13.0}, {\"site\": 71, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": null, \"functional effect\": -0.0436, \"times_seen\": null}, {\"site\": 71, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"73\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 72, \"mutant\": \"-\", \"log2 fold change IC90\": 0.08765550154544757, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.09292160189230107, \"functional effect\": -0.0354, \"times_seen\": 19.0}, {\"site\": 72, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04104908410670576, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08499096243656137, \"functional effect\": 0.1093, \"times_seen\": 11.0}, {\"site\": 72, \"mutant\": \"H\", \"log2 fold change IC90\": 0.017825973240836287, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08853110919440842, \"functional effect\": 0.0324, \"times_seen\": 18.0}, {\"site\": 72, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0534744457266964, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.09074593191546054, \"functional effect\": -0.0269, \"times_seen\": 15.0}, {\"site\": 72, \"mutant\": \"K\", \"log2 fold change IC90\": 0.04277245042138719, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.09007526394319053, \"functional effect\": -0.0726, \"times_seen\": 24.0}, {\"site\": 72, \"mutant\": \"M\", \"log2 fold change IC90\": 0.015938907432896523, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08841538493466021, \"functional effect\": 0.0406, \"times_seen\": 10.0}, {\"site\": 72, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 72, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04579609344051964, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.09026424431678771, \"functional effect\": -0.1336, \"times_seen\": 11.0}, {\"site\": 72, \"mutant\": \"T\", \"log2 fold change IC90\": -0.015552581032325537, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.0865063443021591, \"functional effect\": 0.0316, \"times_seen\": 12.0}, {\"site\": 72, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.017470040558595475, \"epitope\": \"all\", \"reference_site\": \"74\", \"IC90\": 0.08639144667716343, \"functional effect\": 0.2905, \"times_seen\": 5.0}, {\"site\": 73, \"mutant\": \"*\", \"log2 fold change IC90\": 0.013934027388172957, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08829260144661079, \"functional effect\": -2.6083, \"times_seen\": 4.0}, {\"site\": 73, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0072020916120933785, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08700850512899923, \"functional effect\": 0.068, \"times_seen\": 24.0}, {\"site\": 73, \"mutant\": \"A\", \"log2 fold change IC90\": -0.5735335879677638, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.05875961469507394, \"functional effect\": 0.0017, \"times_seen\": 177.0}, {\"site\": 73, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006753770229403366, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08703554745862041, \"functional effect\": 0.005, \"times_seen\": 140.0}, {\"site\": 73, \"mutant\": \"D\", \"log2 fold change IC90\": 0.08919087276670824, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09302054525403412, \"functional effect\": 0.1365, \"times_seen\": 192.0}, {\"site\": 73, \"mutant\": \"E\", \"log2 fold change IC90\": 0.8452525971932016, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.1570999831618243, \"functional effect\": 0.1601, \"times_seen\": 41.0}, {\"site\": 73, \"mutant\": \"F\", \"log2 fold change IC90\": 0.08330459941022711, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.0926417896237493, \"functional effect\": 0.0954, \"times_seen\": 53.0}, {\"site\": 73, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 73, \"mutant\": \"H\", \"log2 fold change IC90\": 0.017358480263223397, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08850242609386415, \"functional effect\": 0.0146, \"times_seen\": 36.0}, {\"site\": 73, \"mutant\": \"I\", \"log2 fold change IC90\": 0.2014665680963184, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.10054887896517566, \"functional effect\": 0.1174, \"times_seen\": 59.0}, {\"site\": 73, \"mutant\": \"K\", \"log2 fold change IC90\": -0.05832748116476601, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08397914165323012, \"functional effect\": 0.0065, \"times_seen\": 29.0}, {\"site\": 73, \"mutant\": \"L\", \"log2 fold change IC90\": -0.21660975703556057, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.07525298277910179, \"functional effect\": 0.0908, \"times_seen\": 113.0}, {\"site\": 73, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0824546498692537, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08258637995905319, \"functional effect\": 0.0553, \"times_seen\": 37.0}, {\"site\": 73, \"mutant\": \"N\", \"log2 fold change IC90\": 0.013380741857157616, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.0882587469927564, \"functional effect\": 0.0523, \"times_seen\": 81.0}, {\"site\": 73, \"mutant\": \"P\", \"log2 fold change IC90\": 0.12994270846691935, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09568556063163647, \"functional effect\": 0.0268, \"times_seen\": 92.0}, {\"site\": 73, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0029795360276991547, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08762472793505781, \"functional effect\": 0.1306, \"times_seen\": 24.0}, {\"site\": 73, \"mutant\": \"R\", \"log2 fold change IC90\": 0.261941975685776, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.10485330996164095, \"functional effect\": -0.1142, \"times_seen\": 145.0}, {\"site\": 73, \"mutant\": \"S\", \"log2 fold change IC90\": 0.149409880233956, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09698545518431669, \"functional effect\": 0.0969, \"times_seen\": 255.0}, {\"site\": 73, \"mutant\": \"T\", \"log2 fold change IC90\": -0.17187136534606764, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.07762315960390885, \"functional effect\": 0.0799, \"times_seen\": 89.0}, {\"site\": 73, \"mutant\": \"V\", \"log2 fold change IC90\": 0.10021766376586405, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.09373424285928258, \"functional effect\": 0.0418, \"times_seen\": 159.0}, {\"site\": 73, \"mutant\": \"W\", \"log2 fold change IC90\": -0.038563458864350614, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.08513751993264684, \"functional effect\": 0.1616, \"times_seen\": 39.0}, {\"site\": 73, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.20070158821149114, \"epitope\": \"all\", \"reference_site\": \"75\", \"IC90\": 0.07608736682052311, \"functional effect\": 0.0413, \"times_seen\": 39.0}, {\"site\": 74, \"mutant\": \"*\", \"log2 fold change IC90\": -0.3586457636822123, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.06819721195296838, \"functional effect\": -2.5774, \"times_seen\": 7.0}, {\"site\": 74, \"mutant\": \"-\", \"log2 fold change IC90\": -0.029883320237658977, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08565130356319878, \"functional effect\": 0.0534, \"times_seen\": 16.0}, {\"site\": 74, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04101816221471063, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08499278410326926, \"functional effect\": -0.0788, \"times_seen\": 136.0}, {\"site\": 74, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03738090326410913, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08520733449656696, \"functional effect\": -0.1474, \"times_seen\": 29.0}, {\"site\": 74, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0715415714608958, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08321346260752663, \"functional effect\": -0.0387, \"times_seen\": 38.0}, {\"site\": 74, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0925650924978064, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08200963583896502, \"functional effect\": 0.062, \"times_seen\": 34.0}, {\"site\": 74, \"mutant\": \"F\", \"log2 fold change IC90\": 0.09960578359788051, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.0936944964390353, \"functional effect\": -0.0331, \"times_seen\": 56.0}, {\"site\": 74, \"mutant\": \"G\", \"log2 fold change IC90\": 0.1998949957627591, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.10043940759723458, \"functional effect\": -0.0309, \"times_seen\": 53.0}, {\"site\": 74, \"mutant\": \"H\", \"log2 fold change IC90\": 0.5110463651409106, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.12461491853512947, \"functional effect\": -0.0401, \"times_seen\": 87.0}, {\"site\": 74, \"mutant\": \"I\", \"log2 fold change IC90\": 0.9413945009620854, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.16792591963680348, \"functional effect\": -0.0742, \"times_seen\": 206.0}, {\"site\": 74, \"mutant\": \"K\", \"log2 fold change IC90\": 0.09334476642298657, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.09328876150586521, \"functional effect\": -0.1361, \"times_seen\": 65.0}, {\"site\": 74, \"mutant\": \"L\", \"log2 fold change IC90\": 0.23161422472048426, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.1026721323760492, \"functional effect\": 0.0384, \"times_seen\": 145.0}, {\"site\": 74, \"mutant\": \"M\", \"log2 fold change IC90\": 0.02029956432781011, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08868303153391205, \"functional effect\": 0.0083, \"times_seen\": 43.0}, {\"site\": 74, \"mutant\": \"N\", \"log2 fold change IC90\": 0.032373216692133014, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08942831792628653, \"functional effect\": -0.0385, \"times_seen\": 153.0}, {\"site\": 74, \"mutant\": \"P\", \"log2 fold change IC90\": -0.12523735906163164, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08017326146897767, \"functional effect\": 0.0178, \"times_seen\": 148.0}, {\"site\": 74, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.6693252108949375, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.1390646407340097, \"functional effect\": -0.0973, \"times_seen\": 24.0}, {\"site\": 74, \"mutant\": \"R\", \"log2 fold change IC90\": 0.4556472738902512, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.11992045004949788, \"functional effect\": -0.0877, \"times_seen\": 134.0}, {\"site\": 74, \"mutant\": \"S\", \"log2 fold change IC90\": 0.010609050400407497, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08808934793615213, \"functional effect\": 0.0426, \"times_seen\": 190.0}, {\"site\": 74, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 74, \"mutant\": \"V\", \"log2 fold change IC90\": -0.137928809916234, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.079471066956391, \"functional effect\": 0.0431, \"times_seen\": 93.0}, {\"site\": 74, \"mutant\": \"W\", \"log2 fold change IC90\": -0.06920358920957918, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.08334842482764486, \"functional effect\": 0.0581, \"times_seen\": 32.0}, {\"site\": 74, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.1131159963705783, \"epitope\": \"all\", \"reference_site\": \"76\", \"IC90\": 0.09457602585267036, \"functional effect\": -0.0973, \"times_seen\": 83.0}, {\"site\": 75, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": null, \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 75, \"mutant\": \"-\", \"log2 fold change IC90\": -0.03444835092065915, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08538071077689802, \"functional effect\": 0.0154, \"times_seen\": 16.0}, {\"site\": 75, \"mutant\": \"C\", \"log2 fold change IC90\": -0.08079858436909056, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08268123505930512, \"functional effect\": 0.0372, \"times_seen\": 19.0}, {\"site\": 75, \"mutant\": \"E\", \"log2 fold change IC90\": 0.013346665544495805, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08825666235459387, \"functional effect\": 0.0428, \"times_seen\": 17.0}, {\"site\": 75, \"mutant\": \"G\", \"log2 fold change IC90\": -0.051377840083364865, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08438465552336001, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 75, \"mutant\": \"I\", \"log2 fold change IC90\": 0.018441726983743828, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08856890304226177, \"functional effect\": 0.0788, \"times_seen\": 17.0}, {\"site\": 75, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 75, \"mutant\": \"M\", \"log2 fold change IC90\": 0.5981756546393168, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.13237274276685349, \"functional effect\": -0.0458, \"times_seen\": 55.0}, {\"site\": 75, \"mutant\": \"N\", \"log2 fold change IC90\": 0.7657332851561474, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.1486751688278588, \"functional effect\": 0.0151, \"times_seen\": 72.0}, {\"site\": 75, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 75, \"mutant\": \"R\", \"log2 fold change IC90\": 0.07331613118700127, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.09200260143316415, \"functional effect\": 0.0427, \"times_seen\": 119.0}, {\"site\": 75, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04617662305471926, \"epitope\": \"all\", \"reference_site\": \"77\", \"IC90\": 0.08468942889179464, \"functional effect\": 0.0471, \"times_seen\": 42.0}, {\"site\": 76, \"mutant\": \"-\", \"log2 fold change IC90\": -0.06147541321310352, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08379610059552886, \"functional effect\": 0.2354, \"times_seen\": 16.0}, {\"site\": 76, \"mutant\": \"G\", \"log2 fold change IC90\": -0.11622794876782402, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08067549781034766, \"functional effect\": 0.1019, \"times_seen\": 78.0}, {\"site\": 76, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": null, \"functional effect\": 0.0957, \"times_seen\": null}, {\"site\": 76, \"mutant\": \"K\", \"log2 fold change IC90\": 0.029221626433277137, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08923317356924877, \"functional effect\": 0.1084, \"times_seen\": 114.0}, {\"site\": 76, \"mutant\": \"L\", \"log2 fold change IC90\": 0.04242725243660818, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.09005371394194034, \"functional effect\": 0.0788, \"times_seen\": 32.0}, {\"site\": 76, \"mutant\": \"M\", \"log2 fold change IC90\": 0.25378678037714525, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.10426227241491093, \"functional effect\": 0.0973, \"times_seen\": 89.0}, {\"site\": 76, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 76, \"mutant\": \"S\", \"log2 fold change IC90\": 0.4890192536592654, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.12272674521642389, \"functional effect\": 0.0149, \"times_seen\": 147.0}, {\"site\": 76, \"mutant\": \"T\", \"log2 fold change IC90\": -0.024232068506798748, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08598747047689491, \"functional effect\": 0.093, \"times_seen\": 22.0}, {\"site\": 76, \"mutant\": \"W\", \"log2 fold change IC90\": -0.040935886910237446, \"epitope\": \"all\", \"reference_site\": \"78\", \"IC90\": 0.08499763128607071, \"functional effect\": -0.0796, \"times_seen\": 44.0}, {\"site\": 77, \"mutant\": \"-\", \"log2 fold change IC90\": 0.004367974657177684, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08770909789237517, \"functional effect\": -0.0415, \"times_seen\": 15.0}, {\"site\": 77, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": null, \"functional effect\": 0.0182, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": null, \"functional effect\": 0.4525, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"L\", \"log2 fold change IC90\": -0.027092922898036973, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08581712686242984, \"functional effect\": 0.0478, \"times_seen\": 69.0}, {\"site\": 77, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02140276193384982, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08875087145916521, \"functional effect\": -0.0869, \"times_seen\": 28.0}, {\"site\": 77, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": null, \"functional effect\": -1.6337, \"times_seen\": null}, {\"site\": 77, \"mutant\": \"W\", \"log2 fold change IC90\": 0.006213247690167219, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08782135362047697, \"functional effect\": -0.1149, \"times_seen\": 16.0}, {\"site\": 77, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01068642655961426, \"epitope\": \"all\", \"reference_site\": \"79\", \"IC90\": 0.08809407256471348, \"functional effect\": 0.0759, \"times_seen\": 11.0}, {\"site\": 78, \"mutant\": \"*\", \"log2 fold change IC90\": 0.020272410966375727, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.0886813624218135, \"functional effect\": -2.1444, \"times_seen\": 2.0}, {\"site\": 78, \"mutant\": \"-\", \"log2 fold change IC90\": -0.016597669257904703, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08644370180191825, \"functional effect\": 0.0333, \"times_seen\": 29.0}, {\"site\": 78, \"mutant\": \"A\", \"log2 fold change IC90\": -0.25622497170188546, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.07321471070932237, \"functional effect\": 0.059, \"times_seen\": 252.0}, {\"site\": 78, \"mutant\": \"C\", \"log2 fold change IC90\": 0.3941651683431181, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.11491726774923393, \"functional effect\": -0.0759, \"times_seen\": 60.0}, {\"site\": 78, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 78, \"mutant\": \"E\", \"log2 fold change IC90\": 0.12351782151578912, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09526038273970565, \"functional effect\": 0.0457, \"times_seen\": 82.0}, {\"site\": 78, \"mutant\": \"F\", \"log2 fold change IC90\": -0.11502476314285225, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08074280800703003, \"functional effect\": -0.2209, \"times_seen\": 95.0}, {\"site\": 78, \"mutant\": \"G\", \"log2 fold change IC90\": 0.10141025439071577, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.0938117594462959, \"functional effect\": 0.1373, \"times_seen\": 192.0}, {\"site\": 78, \"mutant\": \"H\", \"log2 fold change IC90\": -0.5018040581760087, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.06175493648295599, \"functional effect\": -0.0554, \"times_seen\": 193.0}, {\"site\": 78, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04207185357778768, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08493073116505699, \"functional effect\": 0.0006, \"times_seen\": 57.0}, {\"site\": 78, \"mutant\": \"K\", \"log2 fold change IC90\": 0.07160770237066501, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09189371711450826, \"functional effect\": 0.0778, \"times_seen\": 30.0}, {\"site\": 78, \"mutant\": \"L\", \"log2 fold change IC90\": -0.114762246046075, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08075750154623061, \"functional effect\": -0.0148, \"times_seen\": 128.0}, {\"site\": 78, \"mutant\": \"M\", \"log2 fold change IC90\": 0.005526189762601784, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08777954021553068, \"functional effect\": 0.0204, \"times_seen\": 32.0}, {\"site\": 78, \"mutant\": \"N\", \"log2 fold change IC90\": -0.7290555795788964, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.052754821130477345, \"functional effect\": 0.0226, \"times_seen\": 225.0}, {\"site\": 78, \"mutant\": \"P\", \"log2 fold change IC90\": 0.4727697796215945, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.1213521953749546, \"functional effect\": 0.0158, \"times_seen\": 155.0}, {\"site\": 78, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.058723449241679555, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09107669709414397, \"functional effect\": -0.0104, \"times_seen\": 33.0}, {\"site\": 78, \"mutant\": \"R\", \"log2 fold change IC90\": -0.13208154185504173, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.07979381818758, \"functional effect\": 0.0699, \"times_seen\": 136.0}, {\"site\": 78, \"mutant\": \"S\", \"log2 fold change IC90\": -0.003400988645094143, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08723805077056, \"functional effect\": -0.0119, \"times_seen\": 192.0}, {\"site\": 78, \"mutant\": \"T\", \"log2 fold change IC90\": 0.10629105528025792, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.09412967272957279, \"functional effect\": -0.0334, \"times_seen\": 127.0}, {\"site\": 78, \"mutant\": \"V\", \"log2 fold change IC90\": 0.6237445375727175, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.13473969758322113, \"functional effect\": 0.0193, \"times_seen\": 151.0}, {\"site\": 78, \"mutant\": \"W\", \"log2 fold change IC90\": 1.048181120699735e-05, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.0874445824171587, \"functional effect\": -0.1933, \"times_seen\": 40.0}, {\"site\": 78, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.021542112512071873, \"epitope\": \"all\", \"reference_site\": \"80\", \"IC90\": 0.08875944436072432, \"functional effect\": -0.079, \"times_seen\": 196.0}, {\"site\": 79, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": null, \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 79, \"mutant\": \"-\", \"log2 fold change IC90\": -0.06663058804071945, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08349720675283298, \"functional effect\": 0.0751, \"times_seen\": 11.0}, {\"site\": 79, \"mutant\": \"D\", \"log2 fold change IC90\": 0.11315214184552204, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.09457839540278312, \"functional effect\": 0.1318, \"times_seen\": 47.0}, {\"site\": 79, \"mutant\": \"G\", \"log2 fold change IC90\": -0.054600203365455686, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08419638665186417, \"functional effect\": -1.455, \"times_seen\": 1.0}, {\"site\": 79, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005435899756874083, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.0871150888581921, \"functional effect\": -1.0138, \"times_seen\": 1.0}, {\"site\": 79, \"mutant\": \"K\", \"log2 fold change IC90\": 0.06989555586441863, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.09178472513860457, \"functional effect\": -0.2249, \"times_seen\": 29.0}, {\"site\": 79, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 79, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005879633300009063, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08708829875924069, \"functional effect\": 0.1303, \"times_seen\": 15.0}, {\"site\": 79, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0590792512545247, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.0839353925870576, \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 79, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03640723327566114, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.08526486004725078, \"functional effect\": -0.0202, \"times_seen\": 51.0}, {\"site\": 79, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.16736892002415066, \"epitope\": \"all\", \"reference_site\": \"81\", \"IC90\": 0.09820030080105963, \"functional effect\": -0.0555, \"times_seen\": 17.0}, {\"site\": 80, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00813289373158919, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08695238683762585, \"functional effect\": -0.752, \"times_seen\": 2.0}, {\"site\": 80, \"mutant\": \"H\", \"log2 fold change IC90\": -0.27507566925140253, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.07226428754228577, \"functional effect\": -0.0307, \"times_seen\": 60.0}, {\"site\": 80, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08708118955465902, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08232196013904945, \"functional effect\": -0.2553, \"times_seen\": 53.0}, {\"site\": 80, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 80, \"mutant\": \"R\", \"log2 fold change IC90\": 0.06391382620206362, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.09140495341514127, \"functional effect\": 0.0107, \"times_seen\": 9.0}, {\"site\": 80, \"mutant\": \"S\", \"log2 fold change IC90\": -0.003684367442766971, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08722091687499146, \"functional effect\": -0.2198, \"times_seen\": 14.0}, {\"site\": 80, \"mutant\": \"T\", \"log2 fold change IC90\": -0.09406015414009461, \"epitope\": \"all\", \"reference_site\": \"82\", \"IC90\": 0.08192469345727496, \"functional effect\": -0.1073, \"times_seen\": 16.0}, {\"site\": 81, \"mutant\": \"A\", \"log2 fold change IC90\": -0.033023870105334675, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08546505517724316, \"functional effect\": 0.0657, \"times_seen\": 15.0}, {\"site\": 81, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04024114587535758, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08503857241447797, \"functional effect\": -0.4, \"times_seen\": 12.0}, {\"site\": 81, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": null, \"functional effect\": -0.1781, \"times_seen\": null}, {\"site\": 81, \"mutant\": \"F\", \"log2 fold change IC90\": 0.008689779914202883, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08797223733933139, \"functional effect\": 0.1143, \"times_seen\": 33.0}, {\"site\": 81, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 81, \"mutant\": \"I\", \"log2 fold change IC90\": 0.3265515076928254, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.10965578588707388, \"functional effect\": 0.14, \"times_seen\": 34.0}, {\"site\": 81, \"mutant\": \"L\", \"log2 fold change IC90\": -2.8023306064742983, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.01253557277471688, \"functional effect\": -0.051, \"times_seen\": 33.0}, {\"site\": 81, \"mutant\": \"M\", \"log2 fold change IC90\": 0.013161996002706934, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08824536594484594, \"functional effect\": -0.0638, \"times_seen\": 5.0}, {\"site\": 81, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": null, \"functional effect\": -3.251, \"times_seen\": null}, {\"site\": 81, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07929475767584115, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.08276746469948576, \"functional effect\": -0.0464, \"times_seen\": 13.0}, {\"site\": 81, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"83\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 82, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06455091120021399, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.09144532617752052, \"functional effect\": 0.2581, \"times_seen\": 24.0}, {\"site\": 82, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 82, \"mutant\": \"M\", \"log2 fold change IC90\": 0.012601578609364164, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.0882110935362583, \"functional effect\": -0.0035, \"times_seen\": 10.0}, {\"site\": 82, \"mutant\": \"P\", \"log2 fold change IC90\": -0.07422109163589691, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08305905352562584, \"functional effect\": -0.9968, \"times_seen\": 19.0}, {\"site\": 82, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.030793147304455787, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08559730510554196, \"functional effect\": -0.0575, \"times_seen\": 27.0}, {\"site\": 82, \"mutant\": \"V\", \"log2 fold change IC90\": -0.11684238321423634, \"epitope\": \"all\", \"reference_site\": \"84\", \"IC90\": 0.08064114595551974, \"functional effect\": -0.1762, \"times_seen\": 21.0}, {\"site\": 83, \"mutant\": \"-\", \"log2 fold change IC90\": 0.06449365893604339, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.09144169731075243, \"functional effect\": -0.4579, \"times_seen\": 22.0}, {\"site\": 83, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": null, \"functional effect\": -0.4456, \"times_seen\": null}, {\"site\": 83, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03810458993434036, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.08516460339458301, \"functional effect\": -0.164, \"times_seen\": 98.0}, {\"site\": 83, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 83, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.047201021844416644, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.08462931573382844, \"functional effect\": -0.1271, \"times_seen\": 19.0}, {\"site\": 83, \"mutant\": \"R\", \"log2 fold change IC90\": -0.006687986392177896, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.08703951618566433, \"functional effect\": -0.2285, \"times_seen\": 2.0}, {\"site\": 83, \"mutant\": \"S\", \"log2 fold change IC90\": 0.1247127835411455, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.09533931812975928, \"functional effect\": 0.0082, \"times_seen\": 51.0}, {\"site\": 83, \"mutant\": \"T\", \"log2 fold change IC90\": 0.39380807777491816, \"epitope\": \"all\", \"reference_site\": \"85\", \"IC90\": 0.11488882736982693, \"functional effect\": -0.0122, \"times_seen\": 22.0}, {\"site\": 84, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0024383468011330576, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08729628000092846, \"functional effect\": -3.0402, \"times_seen\": 1.0}, {\"site\": 84, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 84, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03384221730326852, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.0854165901489738, \"functional effect\": -0.6218, \"times_seen\": 21.0}, {\"site\": 84, \"mutant\": \"L\", \"log2 fold change IC90\": 0.08516358354334119, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.09276124010810181, \"functional effect\": -0.7148, \"times_seen\": 39.0}, {\"site\": 84, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02652660111584992, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08906663720820832, \"functional effect\": -2.3934, \"times_seen\": 2.0}, {\"site\": 84, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03177652795400884, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08939133863728864, \"functional effect\": -0.7449, \"times_seen\": 7.0}, {\"site\": 84, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.020789045428025416, \"epitope\": \"all\", \"reference_site\": \"86\", \"IC90\": 0.08619292650965596, \"functional effect\": -0.0766, \"times_seen\": 22.0}, {\"site\": 85, \"mutant\": \"-\", \"log2 fold change IC90\": -0.02965747624070114, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08566471273585421, \"functional effect\": -2.4263, \"times_seen\": 6.0}, {\"site\": 85, \"mutant\": \"C\", \"log2 fold change IC90\": -0.05018630812140815, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08445437819099216, \"functional effect\": -0.136, \"times_seen\": 9.0}, {\"site\": 85, \"mutant\": \"D\", \"log2 fold change IC90\": 0.021599768094313986, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08876299159666633, \"functional effect\": -0.1528, \"times_seen\": 24.0}, {\"site\": 85, \"mutant\": \"H\", \"log2 fold change IC90\": 0.01704794400903787, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08848337823310708, \"functional effect\": 0.0457, \"times_seen\": 23.0}, {\"site\": 85, \"mutant\": \"I\", \"log2 fold change IC90\": 0.016476395863511517, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.08844833098261466, \"functional effect\": -0.0667, \"times_seen\": 19.0}, {\"site\": 85, \"mutant\": \"K\", \"log2 fold change IC90\": 0.4691892388188047, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.1210513918562905, \"functional effect\": 0.0785, \"times_seen\": 42.0}, {\"site\": 85, \"mutant\": \"M\", \"log2 fold change IC90\": -2.532748160152457, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.015111117590711244, \"functional effect\": -0.2563, \"times_seen\": 13.0}, {\"site\": 85, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 85, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02971491807559129, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.0856613020078864, \"functional effect\": -0.0829, \"times_seen\": 48.0}, {\"site\": 85, \"mutant\": \"T\", \"log2 fold change IC90\": 0.077400799728376, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.09226345533548089, \"functional effect\": -0.0264, \"times_seen\": 17.0}, {\"site\": 85, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.957719458682144, \"epitope\": \"all\", \"reference_site\": \"87\", \"IC90\": 0.0450222783147072, \"functional effect\": 0.1479, \"times_seen\": 24.0}, {\"site\": 86, \"mutant\": \"-\", \"log2 fold change IC90\": 0.0903292669741905, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.09309397438288146, \"functional effect\": -2.9525, \"times_seen\": 4.0}, {\"site\": 86, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00824428205961543, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08694567363294842, \"functional effect\": -0.1467, \"times_seen\": 17.0}, {\"site\": 86, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 86, \"mutant\": \"E\", \"log2 fold change IC90\": -1.8694071771239065, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.02393217216276351, \"functional effect\": 0.0335, \"times_seen\": 81.0}, {\"site\": 86, \"mutant\": \"G\", \"log2 fold change IC90\": -0.028321999396600052, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.0857440477330811, \"functional effect\": 0.2801, \"times_seen\": 20.0}, {\"site\": 86, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06523245052526669, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08357816437706472, \"functional effect\": -0.1553, \"times_seen\": 54.0}, {\"site\": 86, \"mutant\": \"L\", \"log2 fold change IC90\": 0.004495388024507496, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08771684437010353, \"functional effect\": -0.1074, \"times_seen\": 13.0}, {\"site\": 86, \"mutant\": \"N\", \"log2 fold change IC90\": -0.13516457240204782, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.07962348135157898, \"functional effect\": -0.2114, \"times_seen\": 73.0}, {\"site\": 86, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01611851234411324, \"epitope\": \"all\", \"reference_site\": \"88\", \"IC90\": 0.08842639268433268, \"functional effect\": -0.4421, \"times_seen\": 58.0}, {\"site\": 87, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": null, \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"-\", \"log2 fold change IC90\": 0.012370480484366455, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08819696457267942, \"functional effect\": -2.9064, \"times_seen\": 4.0}, {\"site\": 87, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": null, \"functional effect\": -1.9226, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": null, \"functional effect\": -2.3548, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 87, \"mutant\": \"M\", \"log2 fold change IC90\": -0.030618523599268175, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.0856076664243208, \"functional effect\": -2.258, \"times_seen\": 7.0}, {\"site\": 87, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0005998602344430686, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08740759621017337, \"functional effect\": -2.881, \"times_seen\": 1.0}, {\"site\": 87, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03182334023387566, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08939423923660784, \"functional effect\": -1.9767, \"times_seen\": 8.0}, {\"site\": 87, \"mutant\": \"W\", \"log2 fold change IC90\": -0.013169535278374316, \"epitope\": \"all\", \"reference_site\": \"89\", \"IC90\": 0.08664935368575917, \"functional effect\": -2.8347, \"times_seen\": 3.0}, {\"site\": 88, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008740711451660913, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08691576089222926, \"functional effect\": -2.6703, \"times_seen\": 2.0}, {\"site\": 88, \"mutant\": \"A\", \"log2 fold change IC90\": -0.012316367631011264, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.0867006107334415, \"functional effect\": -0.0255, \"times_seen\": 15.0}, {\"site\": 88, \"mutant\": \"C\", \"log2 fold change IC90\": -0.014585780861745109, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08656433464347273, \"functional effect\": -0.2364, \"times_seen\": 12.0}, {\"site\": 88, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010271527877058604, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08682358513361692, \"functional effect\": -3.1398, \"times_seen\": 2.0}, {\"site\": 88, \"mutant\": \"F\", \"log2 fold change IC90\": 0.012839118803983187, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08822561871645368, \"functional effect\": -0.4407, \"times_seen\": 76.0}, {\"site\": 88, \"mutant\": \"I\", \"log2 fold change IC90\": -0.038087938692978066, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08516558634975382, \"functional effect\": -0.0555, \"times_seen\": 101.0}, {\"site\": 88, \"mutant\": \"L\", \"log2 fold change IC90\": 0.024701580877663325, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08895403846648245, \"functional effect\": -0.183, \"times_seen\": 33.0}, {\"site\": 88, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0181309026035876, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.08854982318944403, \"functional effect\": -0.0793, \"times_seen\": 12.0}, {\"site\": 88, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": null, \"functional effect\": -3.002, \"times_seen\": null}, {\"site\": 88, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": null, \"functional effect\": -0.2691, \"times_seen\": null}, {\"site\": 88, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"90\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": null, \"functional effect\": -2.5509, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": null, \"functional effect\": -3.0806, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004837179040609026, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08715124926019131, \"functional effect\": -2.9475, \"times_seen\": 2.0}, {\"site\": 89, \"mutant\": \"F\", \"log2 fold change IC90\": -0.053897657506099636, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08423739755575534, \"functional effect\": -0.2771, \"times_seen\": 20.0}, {\"site\": 89, \"mutant\": \"H\", \"log2 fold change IC90\": -0.002478064112807147, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.0872938767724308, \"functional effect\": -3.0231, \"times_seen\": 5.0}, {\"site\": 89, \"mutant\": \"L\", \"log2 fold change IC90\": -0.00991729674613334, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08684490592004072, \"functional effect\": -2.8708, \"times_seen\": 1.0}, {\"site\": 89, \"mutant\": \"T\", \"log2 fold change IC90\": 0.018705093057011134, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.08858507289990862, \"functional effect\": -3.114, \"times_seen\": 2.0}, {\"site\": 89, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": null, \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 89, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"91\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 90, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02008660739044201, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.0862349034558158, \"functional effect\": -0.3614, \"times_seen\": 17.0}, {\"site\": 90, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 90, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": null, \"functional effect\": -1.1825, \"times_seen\": null}, {\"site\": 90, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02483202047046946, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08896208150592229, \"functional effect\": -0.1833, \"times_seen\": 15.0}, {\"site\": 90, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06657281267119597, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08350055061860745, \"functional effect\": -0.3369, \"times_seen\": 24.0}, {\"site\": 90, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02754109977468482, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08579047169459049, \"functional effect\": -0.6505, \"times_seen\": 6.0}, {\"site\": 90, \"mutant\": \"V\", \"log2 fold change IC90\": 0.002769435879246377, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08761196804653959, \"functional effect\": -0.2806, \"times_seen\": 12.0}, {\"site\": 90, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.030122318185972094, \"epitope\": \"all\", \"reference_site\": \"92\", \"IC90\": 0.08563711567888685, \"functional effect\": -0.0885, \"times_seen\": 10.0}, {\"site\": 91, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 91, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0011157510777686892, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08737634586558882, \"functional effect\": -0.5236, \"times_seen\": 17.0}, {\"site\": 91, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0023490629004434445, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08730168266286056, \"functional effect\": -2.5734, \"times_seen\": 1.0}, {\"site\": 91, \"mutant\": \"I\", \"log2 fold change IC90\": 0.08307903044142426, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.09262730598113009, \"functional effect\": -2.5408, \"times_seen\": 5.0}, {\"site\": 91, \"mutant\": \"L\", \"log2 fold change IC90\": -0.037554023913638004, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.0851971103926121, \"functional effect\": -0.2054, \"times_seen\": 10.0}, {\"site\": 91, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": null, \"functional effect\": -3.2479, \"times_seen\": null}, {\"site\": 91, \"mutant\": \"P\", \"log2 fold change IC90\": -0.009786153410303875, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08685280062266347, \"functional effect\": -2.4163, \"times_seen\": 2.0}, {\"site\": 91, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06478926023472857, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08360384320725107, \"functional effect\": -0.2226, \"times_seen\": 67.0}, {\"site\": 91, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05264759137628439, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08431041919158837, \"functional effect\": -0.5812, \"times_seen\": 29.0}, {\"site\": 91, \"mutant\": \"V\", \"log2 fold change IC90\": -0.10305763410461753, \"epitope\": \"all\", \"reference_site\": \"93\", \"IC90\": 0.08141535364667728, \"functional effect\": -0.9631, \"times_seen\": 56.0}, {\"site\": 92, \"mutant\": \"A\", \"log2 fold change IC90\": -0.7230105564418162, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.05297633237020244, \"functional effect\": -0.0349, \"times_seen\": 73.0}, {\"site\": 92, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02310193048644403, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.0860548553219392, \"functional effect\": -0.2343, \"times_seen\": 26.0}, {\"site\": 92, \"mutant\": \"F\", \"log2 fold change IC90\": 0.006180274024597819, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08781934643339323, \"functional effect\": -0.3526, \"times_seen\": 48.0}, {\"site\": 92, \"mutant\": \"G\", \"log2 fold change IC90\": 0.004633095882764022, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.0877252175015989, \"functional effect\": 0.1911, \"times_seen\": 21.0}, {\"site\": 92, \"mutant\": \"I\", \"log2 fold change IC90\": -0.009248793526920263, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08688515666629804, \"functional effect\": -0.2027, \"times_seen\": 6.0}, {\"site\": 92, \"mutant\": \"L\", \"log2 fold change IC90\": 0.10746706427059713, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.09420643356109361, \"functional effect\": -0.3224, \"times_seen\": 13.0}, {\"site\": 92, \"mutant\": \"N\", \"log2 fold change IC90\": 0.002056680496996866, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08756869453618453, \"functional effect\": -0.155, \"times_seen\": 42.0}, {\"site\": 92, \"mutant\": \"P\", \"log2 fold change IC90\": -0.01906178224441201, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08629618258376692, \"functional effect\": -2.3846, \"times_seen\": 6.0}, {\"site\": 92, \"mutant\": \"R\", \"log2 fold change IC90\": -0.032230446367651204, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08551207041704902, \"functional effect\": -0.2821, \"times_seen\": 6.0}, {\"site\": 92, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 92, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013158161010931275, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08665003683554469, \"functional effect\": -0.0316, \"times_seen\": 29.0}, {\"site\": 92, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 92, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018113647904096718, \"epitope\": \"all\", \"reference_site\": \"94\", \"IC90\": 0.08635291478548282, \"functional effect\": -0.5048, \"times_seen\": 16.0}, {\"site\": 93, \"mutant\": \"*\", \"log2 fold change IC90\": -0.01103006605182404, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08677794714961169, \"functional effect\": -3.0486, \"times_seen\": 3.0}, {\"site\": 93, \"mutant\": \"A\", \"log2 fold change IC90\": 0.5024632593260822, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.1238757410672543, \"functional effect\": -0.1267, \"times_seen\": 107.0}, {\"site\": 93, \"mutant\": \"C\", \"log2 fold change IC90\": -0.09044804429975516, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08213006725047263, \"functional effect\": -0.1959, \"times_seen\": 45.0}, {\"site\": 93, \"mutant\": \"D\", \"log2 fold change IC90\": 0.5223927297486353, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.12559884162305016, \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 93, \"mutant\": \"E\", \"log2 fold change IC90\": -1.924517352163557, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.023035216725727916, \"functional effect\": -0.4635, \"times_seen\": 27.0}, {\"site\": 93, \"mutant\": \"F\", \"log2 fold change IC90\": 0.042720577462816725, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.0900720252917066, \"functional effect\": -0.224, \"times_seen\": 76.0}, {\"site\": 93, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04158774556196689, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08495923514247228, \"functional effect\": -0.5816, \"times_seen\": 36.0}, {\"site\": 93, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06908522337580651, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08335526342502084, \"functional effect\": -0.2237, \"times_seen\": 50.0}, {\"site\": 93, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 93, \"mutant\": \"K\", \"log2 fold change IC90\": -0.019345680753776583, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08627920259386668, \"functional effect\": -0.1445, \"times_seen\": 30.0}, {\"site\": 93, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06935482958445542, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08333968771692808, \"functional effect\": -0.0639, \"times_seen\": 116.0}, {\"site\": 93, \"mutant\": \"M\", \"log2 fold change IC90\": -0.011597913568484115, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08674379790533233, \"functional effect\": -0.0785, \"times_seen\": 50.0}, {\"site\": 93, \"mutant\": \"N\", \"log2 fold change IC90\": 0.8076004634337941, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.1530529542503465, \"functional effect\": -0.3256, \"times_seen\": 48.0}, {\"site\": 93, \"mutant\": \"P\", \"log2 fold change IC90\": -0.5691460753820704, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.05893858596900259, \"functional effect\": -0.8856, \"times_seen\": 65.0}, {\"site\": 93, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.10782395671860116, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.09422974113664888, \"functional effect\": -0.2541, \"times_seen\": 19.0}, {\"site\": 93, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0877272296156981, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.09292622189354176, \"functional effect\": -0.1713, \"times_seen\": 73.0}, {\"site\": 93, \"mutant\": \"S\", \"log2 fold change IC90\": -0.1520583428820533, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.07869653856697702, \"functional effect\": -0.112, \"times_seen\": 173.0}, {\"site\": 93, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0032068141253449867, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08724979306268238, \"functional effect\": -0.1663, \"times_seen\": 146.0}, {\"site\": 93, \"mutant\": \"V\", \"log2 fold change IC90\": 0.006588889822372483, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08784422310763614, \"functional effect\": 0.1071, \"times_seen\": 81.0}, {\"site\": 93, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0698247200008918, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.09178021864868977, \"functional effect\": -0.1706, \"times_seen\": 20.0}, {\"site\": 93, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.010241625298934933, \"epitope\": \"all\", \"reference_site\": \"95\", \"IC90\": 0.08806691622638303, \"functional effect\": -0.2847, \"times_seen\": 33.0}, {\"site\": 94, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005757455053044224, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08709567436249346, \"functional effect\": -2.3838, \"times_seen\": 1.0}, {\"site\": 94, \"mutant\": \"A\", \"log2 fold change IC90\": -0.5662589168997922, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.05905665348608336, \"functional effect\": -0.0316, \"times_seen\": 46.0}, {\"site\": 94, \"mutant\": \"D\", \"log2 fold change IC90\": 0.24573325048548658, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.10368187254144724, \"functional effect\": -0.0467, \"times_seen\": 99.0}, {\"site\": 94, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 94, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04410984105994242, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.0848108405675772, \"functional effect\": -0.1099, \"times_seen\": 9.0}, {\"site\": 94, \"mutant\": \"K\", \"log2 fold change IC90\": -0.10273581535096189, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08143351681312026, \"functional effect\": -0.3729, \"times_seen\": 43.0}, {\"site\": 94, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0006156113604505177, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08748126820195182, \"functional effect\": -0.3496, \"times_seen\": 18.0}, {\"site\": 94, \"mutant\": \"P\", \"log2 fold change IC90\": -0.034731918645729616, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08536393049140306, \"functional effect\": -0.5903, \"times_seen\": 11.0}, {\"site\": 94, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.009471684598950748, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08801992901778215, \"functional effect\": -0.0732, \"times_seen\": 58.0}, {\"site\": 94, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05259955963561913, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.08431322619063347, \"functional effect\": -0.3448, \"times_seen\": 69.0}, {\"site\": 94, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.05363361915394964, \"epitope\": \"all\", \"reference_site\": \"96\", \"IC90\": 0.09075594452203274, \"functional effect\": -0.3054, \"times_seen\": 13.0}, {\"site\": 95, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": null, \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 95, \"mutant\": \"E\", \"log2 fold change IC90\": -0.06240482167592764, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08374213511969303, \"functional effect\": 0.0891, \"times_seen\": 71.0}, {\"site\": 95, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 95, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01748523792895536, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08639053663321186, \"functional effect\": -0.124, \"times_seen\": 10.0}, {\"site\": 95, \"mutant\": \"M\", \"log2 fold change IC90\": 0.462411452135112, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.12048402575337208, \"functional effect\": 0.0141, \"times_seen\": 20.0}, {\"site\": 95, \"mutant\": \"N\", \"log2 fold change IC90\": -0.09270607706710336, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.082001621998246, \"functional effect\": 0.0086, \"times_seen\": 76.0}, {\"site\": 95, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.024987112100625826, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.08897164556172826, \"functional effect\": 0.0609, \"times_seen\": 23.0}, {\"site\": 95, \"mutant\": \"R\", \"log2 fold change IC90\": 0.31467187653733486, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.1087565510286335, \"functional effect\": 0.0146, \"times_seen\": 65.0}, {\"site\": 95, \"mutant\": \"T\", \"log2 fold change IC90\": 2.6520283667264586, \"epitope\": \"all\", \"reference_site\": \"97\", \"IC90\": 0.5496292547379794, \"functional effect\": 0.2037, \"times_seen\": 7.0}, {\"site\": 96, \"mutant\": \"*\", \"log2 fold change IC90\": 0.1253743208236765, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09538304530294436, \"functional effect\": -2.5427, \"times_seen\": 6.0}, {\"site\": 96, \"mutant\": \"A\", \"log2 fold change IC90\": 0.12458029048847521, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09533056283711328, \"functional effect\": 0.0308, \"times_seen\": 172.0}, {\"site\": 96, \"mutant\": \"C\", \"log2 fold change IC90\": -0.12530488285127492, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08016950913352071, \"functional effect\": -0.1456, \"times_seen\": 77.0}, {\"site\": 96, \"mutant\": \"D\", \"log2 fold change IC90\": -0.10025608005511041, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08157360685538975, \"functional effect\": 0.0324, \"times_seen\": 60.0}, {\"site\": 96, \"mutant\": \"E\", \"log2 fold change IC90\": -0.04191496328485613, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08493996771988215, \"functional effect\": 0.0439, \"times_seen\": 46.0}, {\"site\": 96, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04879249147077326, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.0845360106887901, \"functional effect\": -0.1165, \"times_seen\": 204.0}, {\"site\": 96, \"mutant\": \"G\", \"log2 fold change IC90\": -0.16597443448892987, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.07794108900502826, \"functional effect\": -0.0492, \"times_seen\": 122.0}, {\"site\": 96, \"mutant\": \"H\", \"log2 fold change IC90\": 0.17854359758162722, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09896388392582468, \"functional effect\": -0.0515, \"times_seen\": 88.0}, {\"site\": 96, \"mutant\": \"I\", \"log2 fold change IC90\": 0.23732951226770865, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.10307967838912228, \"functional effect\": -0.0559, \"times_seen\": 133.0}, {\"site\": 96, \"mutant\": \"K\", \"log2 fold change IC90\": 0.2217761931612726, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.10197437196608508, \"functional effect\": -0.0309, \"times_seen\": 59.0}, {\"site\": 96, \"mutant\": \"L\", \"log2 fold change IC90\": -0.2746445516898635, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.07228588535604058, \"functional effect\": -0.0364, \"times_seen\": 168.0}, {\"site\": 96, \"mutant\": \"M\", \"log2 fold change IC90\": -0.5722776762773965, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.05881078907046878, \"functional effect\": 0.0211, \"times_seen\": 43.0}, {\"site\": 96, \"mutant\": \"N\", \"log2 fold change IC90\": -0.10119513185112744, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.0815205277810524, \"functional effect\": -0.074, \"times_seen\": 150.0}, {\"site\": 96, \"mutant\": \"P\", \"log2 fold change IC90\": -0.017524197059543545, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08638820373910817, \"functional effect\": -0.1268, \"times_seen\": 162.0}, {\"site\": 96, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0721168293935197, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08318028881768702, \"functional effect\": -0.0761, \"times_seen\": 70.0}, {\"site\": 96, \"mutant\": \"R\", \"log2 fold change IC90\": 0.45748092157882986, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.1200729643709288, \"functional effect\": -0.0237, \"times_seen\": 304.0}, {\"site\": 96, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 96, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07611370951126406, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09218117984999298, \"functional effect\": -0.0523, \"times_seen\": 182.0}, {\"site\": 96, \"mutant\": \"V\", \"log2 fold change IC90\": -0.13042380925515862, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.07988555818498581, \"functional effect\": -0.0558, \"times_seen\": 130.0}, {\"site\": 96, \"mutant\": \"W\", \"log2 fold change IC90\": 0.042007395247735564, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.09002751006870126, \"functional effect\": -0.083, \"times_seen\": 60.0}, {\"site\": 96, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04783092656884751, \"epitope\": \"all\", \"reference_site\": \"98\", \"IC90\": 0.08459237322808785, \"functional effect\": -0.001, \"times_seen\": 111.0}, {\"site\": 97, \"mutant\": \"D\", \"log2 fold change IC90\": -0.17083237837031073, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.07767908167837748, \"functional effect\": -0.0318, \"times_seen\": 88.0}, {\"site\": 97, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": null, \"functional effect\": -0.6425, \"times_seen\": null}, {\"site\": 97, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": null, \"functional effect\": -0.4147, \"times_seen\": null}, {\"site\": 97, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0011560489729196045, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.08737390527104255, \"functional effect\": -0.3138, \"times_seen\": 1.0}, {\"site\": 97, \"mutant\": \"K\", \"log2 fold change IC90\": -0.3808114900741423, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.06715743054756772, \"functional effect\": 0.0587, \"times_seen\": 54.0}, {\"site\": 97, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 97, \"mutant\": \"S\", \"log2 fold change IC90\": 0.06171911600446614, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.09126600868508832, \"functional effect\": -0.0383, \"times_seen\": 94.0}, {\"site\": 97, \"mutant\": \"T\", \"log2 fold change IC90\": -0.01780652496782857, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.08637129967147911, \"functional effect\": -0.0293, \"times_seen\": 39.0}, {\"site\": 97, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.12188138430417939, \"epitope\": \"all\", \"reference_site\": \"99\", \"IC90\": 0.0951523909236433, \"functional effect\": -0.0632, \"times_seen\": 47.0}, {\"site\": 98, \"mutant\": \"-\", \"log2 fold change IC90\": -0.00424185657873862, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08718721930302417, \"functional effect\": -0.4301, \"times_seen\": 1.0}, {\"site\": 98, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": null, \"functional effect\": -0.0746, \"times_seen\": null}, {\"site\": 98, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0934799169885646, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08195764935571608, \"functional effect\": 0.0559, \"times_seen\": 57.0}, {\"site\": 98, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 98, \"mutant\": \"K\", \"log2 fold change IC90\": 0.01801716568726153, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08854284251330677, \"functional effect\": -0.1329, \"times_seen\": 25.0}, {\"site\": 98, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00633049564615171, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08782849115983021, \"functional effect\": -0.0736, \"times_seen\": 64.0}, {\"site\": 98, \"mutant\": \"M\", \"log2 fold change IC90\": 0.031488838241045466, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08937351477024233, \"functional effect\": 0.031, \"times_seen\": 28.0}, {\"site\": 98, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 98, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0014851127170164603, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08753400839010565, \"functional effect\": -0.185, \"times_seen\": 23.0}, {\"site\": 98, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005589968505135994, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08710578613261785, \"functional effect\": -0.1495, \"times_seen\": 1.0}, {\"site\": 98, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05176786355009023, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.08436184574958314, \"functional effect\": 0.0456, \"times_seen\": 125.0}, {\"site\": 98, \"mutant\": \"V\", \"log2 fold change IC90\": -0.16032990946645223, \"epitope\": \"all\", \"reference_site\": \"100\", \"IC90\": 0.0782466297940997, \"functional effect\": 0.0125, \"times_seen\": 75.0}, {\"site\": 99, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 99, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": null, \"functional effect\": -0.1396, \"times_seen\": null}, {\"site\": 99, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 99, \"mutant\": \"L\", \"log2 fold change IC90\": 0.12049374447963536, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.09506091367835093, \"functional effect\": 0.0312, \"times_seen\": 14.0}, {\"site\": 99, \"mutant\": \"M\", \"log2 fold change IC90\": -0.047903584160975496, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.0845881130599935, \"functional effect\": 0.0773, \"times_seen\": 19.0}, {\"site\": 99, \"mutant\": \"N\", \"log2 fold change IC90\": -0.1745225216317743, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.0774806470476964, \"functional effect\": -0.134, \"times_seen\": 38.0}, {\"site\": 99, \"mutant\": \"S\", \"log2 fold change IC90\": 0.009625940906344072, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.08802934081635645, \"functional effect\": -0.1162, \"times_seen\": 1.0}, {\"site\": 99, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0016462922652937385, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.08754378833644243, \"functional effect\": -0.0282, \"times_seen\": 88.0}, {\"site\": 99, \"mutant\": \"V\", \"log2 fold change IC90\": 0.5089838766997226, \"epitope\": \"all\", \"reference_site\": \"101\", \"IC90\": 0.12443689532672313, \"functional effect\": -0.0332, \"times_seen\": 42.0}, {\"site\": 100, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 100, \"mutant\": \"A\", \"log2 fold change IC90\": -0.012961363873584892, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08666185751963162, \"functional effect\": 0.3679, \"times_seen\": 10.0}, {\"site\": 100, \"mutant\": \"G\", \"log2 fold change IC90\": 0.005645076612263523, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08778677408180531, \"functional effect\": 0.0811, \"times_seen\": 72.0}, {\"site\": 100, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04962881288531979, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08448701988614074, \"functional effect\": 0.0793, \"times_seen\": 77.0}, {\"site\": 100, \"mutant\": \"K\", \"log2 fold change IC90\": 0.4363659287841941, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.11832839845068553, \"functional effect\": -0.0588, \"times_seen\": 85.0}, {\"site\": 100, \"mutant\": \"M\", \"log2 fold change IC90\": 0.014389949492371547, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08832050818282981, \"functional effect\": 0.1373, \"times_seen\": 5.0}, {\"site\": 100, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 100, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06899519836713741, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08336046500417196, \"functional effect\": 0.0496, \"times_seen\": 74.0}, {\"site\": 100, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0004610681897760384, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": 0.08747189760866227, \"functional effect\": 0.0622, \"times_seen\": 21.0}, {\"site\": 100, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"102\", \"IC90\": null, \"functional effect\": -0.4304, \"times_seen\": null}, {\"site\": 101, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 101, \"mutant\": \"C\", \"log2 fold change IC90\": -0.05519433776886265, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.084161719816914, \"functional effect\": -1.257, \"times_seen\": 28.0}, {\"site\": 101, \"mutant\": \"D\", \"log2 fold change IC90\": -0.036929864644831285, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.08523397755391802, \"functional effect\": -2.2717, \"times_seen\": 3.0}, {\"site\": 101, \"mutant\": \"F\", \"log2 fold change IC90\": 0.24486317432151747, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.10361936180557176, \"functional effect\": -1.2139, \"times_seen\": 21.0}, {\"site\": 101, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 101, \"mutant\": \"R\", \"log2 fold change IC90\": -1.7178050926709507, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.02658391215826692, \"functional effect\": -1.7102, \"times_seen\": 11.0}, {\"site\": 101, \"mutant\": \"S\", \"log2 fold change IC90\": -0.10277406379612264, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": 0.0814313578924711, \"functional effect\": -0.5601, \"times_seen\": 31.0}, {\"site\": 101, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"103\", \"IC90\": null, \"functional effect\": -1.5467, \"times_seen\": null}, {\"site\": 102, \"mutant\": \"*\", \"log2 fold change IC90\": 0.028670013371560808, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08919906187283601, \"functional effect\": -2.5166, \"times_seen\": 3.0}, {\"site\": 102, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 102, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005369996022977838, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08711906845235842, \"functional effect\": -1.8512, \"times_seen\": 2.0}, {\"site\": 102, \"mutant\": \"F\", \"log2 fold change IC90\": -0.12363845721788261, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08026216469008873, \"functional effect\": -0.187, \"times_seen\": 24.0}, {\"site\": 102, \"mutant\": \"G\", \"log2 fold change IC90\": -0.004016755583499922, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08720082402228849, \"functional effect\": -1.3353, \"times_seen\": 9.0}, {\"site\": 102, \"mutant\": \"L\", \"log2 fold change IC90\": 1.2533151677888277, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.20845638993547522, \"functional effect\": -0.3178, \"times_seen\": 35.0}, {\"site\": 102, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0007128038143700442, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.08740075364113983, \"functional effect\": -2.3409, \"times_seen\": 5.0}, {\"site\": 102, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04717136557416456, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.09035033117740526, \"functional effect\": -1.9068, \"times_seen\": 8.0}, {\"site\": 102, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"104\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 103, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 103, \"mutant\": \"F\", \"log2 fold change IC90\": -0.028627627373732475, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08572588519454787, \"functional effect\": -0.35, \"times_seen\": 23.0}, {\"site\": 103, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 103, \"mutant\": \"L\", \"log2 fold change IC90\": -0.17775660595032322, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.0773071534906374, \"functional effect\": -0.1699, \"times_seen\": 44.0}, {\"site\": 103, \"mutant\": \"N\", \"log2 fold change IC90\": 1.6634241556551088, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.27699397278245874, \"functional effect\": -0.5794, \"times_seen\": 5.0}, {\"site\": 103, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0027878600791723866, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08761308691828766, \"functional effect\": 0.1526, \"times_seen\": 1.0}, {\"site\": 103, \"mutant\": \"T\", \"log2 fold change IC90\": -0.017497843258164485, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08638978181229229, \"functional effect\": -0.1673, \"times_seen\": 106.0}, {\"site\": 103, \"mutant\": \"V\", \"log2 fold change IC90\": -0.030576713452525984, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08561014742055297, \"functional effect\": -0.0713, \"times_seen\": 54.0}, {\"site\": 103, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010176862928794743, \"epitope\": \"all\", \"reference_site\": \"105\", \"IC90\": 0.08682928240131704, \"functional effect\": -0.1562, \"times_seen\": 27.0}, {\"site\": 104, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 104, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 104, \"mutant\": \"I\", \"log2 fold change IC90\": 0.05674711846036917, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.09095201762775201, \"functional effect\": -1.1841, \"times_seen\": 28.0}, {\"site\": 104, \"mutant\": \"L\", \"log2 fold change IC90\": 0.017846280371239334, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.08853235535203777, \"functional effect\": -0.2396, \"times_seen\": 57.0}, {\"site\": 104, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": null, \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 104, \"mutant\": \"V\", \"log2 fold change IC90\": -0.08859028742216489, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.08223589417315151, \"functional effect\": -1.1602, \"times_seen\": 22.0}, {\"site\": 104, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.415534915252299, \"epitope\": \"all\", \"reference_site\": \"106\", \"IC90\": 0.116632135246977, \"functional effect\": -0.067, \"times_seen\": 45.0}, {\"site\": 105, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 105, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": null, \"functional effect\": -2.1019, \"times_seen\": null}, {\"site\": 105, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04894371127944256, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08452715029275745, \"functional effect\": -2.0577, \"times_seen\": 11.0}, {\"site\": 105, \"mutant\": \"D\", \"log2 fold change IC90\": -0.02613443323250109, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08587416050914345, \"functional effect\": -2.5776, \"times_seen\": 3.0}, {\"site\": 105, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 105, \"mutant\": \"L\", \"log2 fold change IC90\": 0.032000226681544036, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08940520038805853, \"functional effect\": -1.6558, \"times_seen\": 9.0}, {\"site\": 105, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03760092894590265, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08519434050144502, \"functional effect\": -2.156, \"times_seen\": 10.0}, {\"site\": 105, \"mutant\": \"S\", \"log2 fold change IC90\": -0.031745186992924085, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.08554083776709029, \"functional effect\": -1.5646, \"times_seen\": 4.0}, {\"site\": 105, \"mutant\": \"V\", \"log2 fold change IC90\": -1.7229500519350973, \"epitope\": \"all\", \"reference_site\": \"107\", \"IC90\": 0.02648927708310144, \"functional effect\": -2.9922, \"times_seen\": 5.0}, {\"site\": 106, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004489974230521228, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08717222595557689, \"functional effect\": -0.7745, \"times_seen\": 7.0}, {\"site\": 106, \"mutant\": \"A\", \"log2 fold change IC90\": -0.025929234144139526, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08588637553184533, \"functional effect\": -0.0697, \"times_seen\": 42.0}, {\"site\": 106, \"mutant\": \"C\", \"log2 fold change IC90\": 0.015349435552008224, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08837926660356123, \"functional effect\": -0.4085, \"times_seen\": 4.0}, {\"site\": 106, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0017276705254005978, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08733929302607307, \"functional effect\": -2.001, \"times_seen\": 1.0}, {\"site\": 106, \"mutant\": \"I\", \"log2 fold change IC90\": 0.5033778217043051, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.12395429405742352, \"functional effect\": -0.3128, \"times_seen\": 90.0}, {\"site\": 106, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0029240209741944767, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08726689720569687, \"functional effect\": -0.2263, \"times_seen\": 4.0}, {\"site\": 106, \"mutant\": \"N\", \"log2 fold change IC90\": -0.1365622832195399, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.07954637794079397, \"functional effect\": 0.3447, \"times_seen\": 47.0}, {\"site\": 106, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02267385504482819, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.08608039324572737, \"functional effect\": 0.152, \"times_seen\": 31.0}, {\"site\": 106, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"108\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 107, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 107, \"mutant\": \"A\", \"log2 fold change IC90\": 0.3189862236048986, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.10908227183572845, \"functional effect\": -0.0787, \"times_seen\": 44.0}, {\"site\": 107, \"mutant\": \"I\", \"log2 fold change IC90\": -1.9867396451893544, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.02206284561643998, \"functional effect\": -1.0708, \"times_seen\": 45.0}, {\"site\": 107, \"mutant\": \"K\", \"log2 fold change IC90\": -0.05744556088897997, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.08403049384314484, \"functional effect\": -0.2012, \"times_seen\": 14.0}, {\"site\": 107, \"mutant\": \"L\", \"log2 fold change IC90\": -0.021398511434728994, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.08615652202859139, \"functional effect\": -0.2797, \"times_seen\": 2.0}, {\"site\": 107, \"mutant\": \"N\", \"log2 fold change IC90\": -2.495740557083755, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.01550375810498678, \"functional effect\": -0.137, \"times_seen\": 39.0}, {\"site\": 107, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": null, \"functional effect\": -3.0375, \"times_seen\": null}, {\"site\": 107, \"mutant\": \"R\", \"log2 fold change IC90\": -0.026341723706446118, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.08586182275504642, \"functional effect\": -0.5204, \"times_seen\": 7.0}, {\"site\": 107, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05011469420004207, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.08445857052488177, \"functional effect\": 0.1497, \"times_seen\": 8.0}, {\"site\": 107, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"109\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0011055701462299422, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.0875109830715884, \"functional effect\": 0.1351, \"times_seen\": 8.0}, {\"site\": 108, \"mutant\": \"I\", \"log2 fold change IC90\": -0.023977180535828535, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08600266364487452, \"functional effect\": -0.373, \"times_seen\": 17.0}, {\"site\": 108, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"M\", \"log2 fold change IC90\": -1.804084574808754, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.025040683619425498, \"functional effect\": -0.0224, \"times_seen\": 17.0}, {\"site\": 108, \"mutant\": \"P\", \"log2 fold change IC90\": -0.053206178783798436, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08427778192509969, \"functional effect\": -1.5686, \"times_seen\": 8.0}, {\"site\": 108, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": null, \"functional effect\": -1.0578, \"times_seen\": null}, {\"site\": 108, \"mutant\": \"V\", \"log2 fold change IC90\": -1.1515823289278573, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.039361254297698364, \"functional effect\": -0.6082, \"times_seen\": 61.0}, {\"site\": 108, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04499070459603052, \"epitope\": \"all\", \"reference_site\": \"110\", \"IC90\": 0.08475907358102862, \"functional effect\": -0.4187, \"times_seen\": 13.0}, {\"site\": 109, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 109, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 109, \"mutant\": \"E\", \"log2 fold change IC90\": 0.04668809482180941, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.09032007089444646, \"functional effect\": -0.2564, \"times_seen\": 38.0}, {\"site\": 109, \"mutant\": \"G\", \"log2 fold change IC90\": -0.2434778499155482, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.07386447522823321, \"functional effect\": -0.2263, \"times_seen\": 77.0}, {\"site\": 109, \"mutant\": \"H\", \"log2 fold change IC90\": -0.21654446556323098, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.07525638855030545, \"functional effect\": -0.2835, \"times_seen\": 160.0}, {\"site\": 109, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03580521059147026, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08964131012622936, \"functional effect\": -1.4678, \"times_seen\": 13.0}, {\"site\": 109, \"mutant\": \"N\", \"log2 fold change IC90\": -0.06686806356276993, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08348346378543689, \"functional effect\": -0.0352, \"times_seen\": 122.0}, {\"site\": 109, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02165773492286834, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08876655812482334, \"functional effect\": -1.9815, \"times_seen\": 12.0}, {\"site\": 109, \"mutant\": \"R\", \"log2 fold change IC90\": 0.1720616408240883, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.09852024151638848, \"functional effect\": -0.1555, \"times_seen\": 16.0}, {\"site\": 109, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0029175599254011603, \"epitope\": \"all\", \"reference_site\": \"111\", \"IC90\": 0.08726728802768452, \"functional effect\": -0.9627, \"times_seen\": 4.0}, {\"site\": 110, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": null, \"functional effect\": 0.2459, \"times_seen\": null}, {\"site\": 110, \"mutant\": \"A\", \"log2 fold change IC90\": -0.2603770046057815, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.0730043038930661, \"functional effect\": -0.1061, \"times_seen\": 30.0}, {\"site\": 110, \"mutant\": \"F\", \"log2 fold change IC90\": 0.7130048521601062, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.14333940598728961, \"functional effect\": -0.0792, \"times_seen\": 51.0}, {\"site\": 110, \"mutant\": \"G\", \"log2 fold change IC90\": -0.011719469360737663, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08673648952304482, \"functional effect\": -0.1917, \"times_seen\": 2.0}, {\"site\": 110, \"mutant\": \"H\", \"log2 fold change IC90\": -0.008859773672587863, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08690858823534059, \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 110, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02080867582612684, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08619175371159284, \"functional effect\": 0.2182, \"times_seen\": 7.0}, {\"site\": 110, \"mutant\": \"K\", \"log2 fold change IC90\": 0.027766091257891153, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08914319161027795, \"functional effect\": 0.0034, \"times_seen\": 23.0}, {\"site\": 110, \"mutant\": \"L\", \"log2 fold change IC90\": -3.4934454056565825, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.007764221159114927, \"functional effect\": -0.126, \"times_seen\": 61.0}, {\"site\": 110, \"mutant\": \"M\", \"log2 fold change IC90\": -0.08155295090616017, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08263801341418753, \"functional effect\": 0.0271, \"times_seen\": 41.0}, {\"site\": 110, \"mutant\": \"N\", \"log2 fold change IC90\": -0.021771685377172993, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08613423927982487, \"functional effect\": 0.0242, \"times_seen\": 59.0}, {\"site\": 110, \"mutant\": \"P\", \"log2 fold change IC90\": -0.011562123025345544, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08674594988205853, \"functional effect\": -0.2199, \"times_seen\": 113.0}, {\"site\": 110, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.07375260393690802, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08308602974889949, \"functional effect\": -0.0148, \"times_seen\": 20.0}, {\"site\": 110, \"mutant\": \"R\", \"log2 fold change IC90\": -0.07994478857451753, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.0827301808042873, \"functional effect\": -0.0657, \"times_seen\": 25.0}, {\"site\": 110, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 110, \"mutant\": \"T\", \"log2 fold change IC90\": -0.10096556858120498, \"epitope\": \"all\", \"reference_site\": \"112\", \"IC90\": 0.08153350045190637, \"functional effect\": -0.069, \"times_seen\": 39.0}, {\"site\": 111, \"mutant\": \"E\", \"log2 fold change IC90\": -0.05166271736402825, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08436799441532936, \"functional effect\": -0.4226, \"times_seen\": 39.0}, {\"site\": 111, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 111, \"mutant\": \"M\", \"log2 fold change IC90\": 0.008611745620046605, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08796747911559208, \"functional effect\": -0.2109, \"times_seen\": 30.0}, {\"site\": 111, \"mutant\": \"N\", \"log2 fold change IC90\": -0.06607905376081583, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08352913337228235, \"functional effect\": -0.2066, \"times_seen\": 55.0}, {\"site\": 111, \"mutant\": \"P\", \"log2 fold change IC90\": 0.015619254138785836, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08839579719263242, \"functional effect\": -0.0809, \"times_seen\": 8.0}, {\"site\": 111, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05268726127809974, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.09069643129369251, \"functional effect\": -0.3784, \"times_seen\": 24.0}, {\"site\": 111, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0748254067487693, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.09209890032664969, \"functional effect\": 0.0556, \"times_seen\": 60.0}, {\"site\": 111, \"mutant\": \"S\", \"log2 fold change IC90\": -0.042102352658640485, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08492893571849106, \"functional effect\": -0.0779, \"times_seen\": 12.0}, {\"site\": 111, \"mutant\": \"T\", \"log2 fold change IC90\": 0.007522771712481663, \"epitope\": \"all\", \"reference_site\": \"113\", \"IC90\": 0.08790110462745164, \"functional effect\": 0.0329, \"times_seen\": 8.0}, {\"site\": 112, \"mutant\": \"A\", \"log2 fold change IC90\": 0.08346492678130632, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.09265208552101327, \"functional effect\": -0.3857, \"times_seen\": 8.0}, {\"site\": 112, \"mutant\": \"I\", \"log2 fold change IC90\": 0.05019994445144134, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.09054019841209426, \"functional effect\": -2.572, \"times_seen\": 4.0}, {\"site\": 112, \"mutant\": \"N\", \"log2 fold change IC90\": -0.008989342701942939, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.08690078329011379, \"functional effect\": -1.8954, \"times_seen\": 2.0}, {\"site\": 112, \"mutant\": \"P\", \"log2 fold change IC90\": -0.013008988992884432, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.08665899675345196, \"functional effect\": -1.9387, \"times_seen\": 4.0}, {\"site\": 112, \"mutant\": \"S\", \"log2 fold change IC90\": 0.019164041723629847, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.08861325797530276, \"functional effect\": 0.1233, \"times_seen\": 11.0}, {\"site\": 112, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"114\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 113, \"mutant\": \"*\", \"log2 fold change IC90\": -0.007766227597299012, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08697448890806628, \"functional effect\": -2.592, \"times_seen\": 2.0}, {\"site\": 113, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03361824335428008, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08950552668737757, \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 113, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0577076705458279, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.09101259400591016, \"functional effect\": -1.5896, \"times_seen\": 12.0}, {\"site\": 113, \"mutant\": \"L\", \"log2 fold change IC90\": 0.022821725220112183, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.0888382053559992, \"functional effect\": -0.535, \"times_seen\": 10.0}, {\"site\": 113, \"mutant\": \"P\", \"log2 fold change IC90\": -0.009304968369751237, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08688177364711461, \"functional effect\": -0.6093, \"times_seen\": 18.0}, {\"site\": 113, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 113, \"mutant\": \"R\", \"log2 fold change IC90\": 0.012699258288038516, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08821706619349233, \"functional effect\": -1.4123, \"times_seen\": 17.0}, {\"site\": 113, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01580784747165259, \"epitope\": \"all\", \"reference_site\": \"115\", \"IC90\": 0.08840735330616348, \"functional effect\": -0.7012, \"times_seen\": 3.0}, {\"site\": 114, \"mutant\": \"D\", \"log2 fold change IC90\": 0.020962133627101254, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08872376928316238, \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 114, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0034981136196419785, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08723217793671921, \"functional effect\": -2.1498, \"times_seen\": 1.0}, {\"site\": 114, \"mutant\": \"K\", \"log2 fold change IC90\": 0.01092313048994922, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08810852740328713, \"functional effect\": -2.2258, \"times_seen\": 2.0}, {\"site\": 114, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004097475359397166, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08719594521293265, \"functional effect\": -3.132, \"times_seen\": 1.0}, {\"site\": 114, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 114, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.023572317493697075, \"epitope\": \"all\", \"reference_site\": \"116\", \"IC90\": 0.08888443731619906, \"functional effect\": -2.842, \"times_seen\": 2.0}, {\"site\": 115, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": null, \"functional effect\": -3.2758, \"times_seen\": null}, {\"site\": 115, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01979379580247154, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08865194719272389, \"functional effect\": -0.4963, \"times_seen\": 9.0}, {\"site\": 115, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 115, \"mutant\": \"M\", \"log2 fold change IC90\": 0.003955922983880679, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.0876840506586197, \"functional effect\": 0.0261, \"times_seen\": 9.0}, {\"site\": 115, \"mutant\": \"P\", \"log2 fold change IC90\": -0.007557870476109669, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08698705085793546, \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 115, \"mutant\": \"R\", \"log2 fold change IC90\": 0.029809460672340474, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08926953953783687, \"functional effect\": -2.7012, \"times_seen\": 2.0}, {\"site\": 115, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0004971392240924399, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08747408465524888, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 115, \"mutant\": \"W\", \"log2 fold change IC90\": 0.015631492250856367, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08839654704081953, \"functional effect\": -1.1639, \"times_seen\": 5.0}, {\"site\": 115, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.013703034960095194, \"epitope\": \"all\", \"reference_site\": \"117\", \"IC90\": 0.08661731721578265, \"functional effect\": -1.6211, \"times_seen\": 4.0}, {\"site\": 116, \"mutant\": \"F\", \"log2 fold change IC90\": 0.06274780318193884, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.09133110744079218, \"functional effect\": -0.2045, \"times_seen\": 40.0}, {\"site\": 116, \"mutant\": \"I\", \"log2 fold change IC90\": -0.34969679782186, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.06862155059507916, \"functional effect\": -0.0168, \"times_seen\": 75.0}, {\"site\": 116, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 116, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06437544264929512, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.08362782727999452, \"functional effect\": -0.0479, \"times_seen\": 32.0}, {\"site\": 116, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": null, \"functional effect\": -2.9821, \"times_seen\": null}, {\"site\": 116, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": null, \"functional effect\": -0.8778, \"times_seen\": null}, {\"site\": 116, \"mutant\": \"V\", \"log2 fold change IC90\": 1.4898709968553334, \"epitope\": \"all\", \"reference_site\": \"118\", \"IC90\": 0.24559844488296323, \"functional effect\": -0.0866, \"times_seen\": 12.0}, {\"site\": 117, \"mutant\": \"-\", \"log2 fold change IC90\": -0.009802306294330168, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.0868518281958357, \"functional effect\": -2.9694, \"times_seen\": 2.0}, {\"site\": 117, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": null, \"functional effect\": -1.067, \"times_seen\": null}, {\"site\": 117, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 117, \"mutant\": \"L\", \"log2 fold change IC90\": -0.024207829784119183, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.085988915164719, \"functional effect\": -0.0081, \"times_seen\": 16.0}, {\"site\": 117, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": null, \"functional effect\": -0.835, \"times_seen\": null}, {\"site\": 117, \"mutant\": \"T\", \"log2 fold change IC90\": -0.007926880973933128, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.08696480427827312, \"functional effect\": -1.8059, \"times_seen\": 1.0}, {\"site\": 117, \"mutant\": \"V\", \"log2 fold change IC90\": -0.21575324247553904, \"epitope\": \"all\", \"reference_site\": \"119\", \"IC90\": 0.07529767303632334, \"functional effect\": -0.2743, \"times_seen\": 33.0}, {\"site\": 118, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0011525171222428895, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.08737411917069247, \"functional effect\": -2.935, \"times_seen\": 1.0}, {\"site\": 118, \"mutant\": \"A\", \"log2 fold change IC90\": 0.4719662444482245, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.12128462488747471, \"functional effect\": -0.2152, \"times_seen\": 10.0}, {\"site\": 118, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": null, \"functional effect\": -0.481, \"times_seen\": null}, {\"site\": 118, \"mutant\": \"F\", \"log2 fold change IC90\": 0.2342384495601144, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.10285906027733108, \"functional effect\": -0.0109, \"times_seen\": 45.0}, {\"site\": 118, \"mutant\": \"I\", \"log2 fold change IC90\": -0.14654342358170547, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.07899794366644779, \"functional effect\": -0.0259, \"times_seen\": 63.0}, {\"site\": 118, \"mutant\": \"L\", \"log2 fold change IC90\": 0.022255946618591815, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.08880337269924662, \"functional effect\": -0.0043, \"times_seen\": 28.0}, {\"site\": 118, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0009405223377885877, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.08750097217572529, \"functional effect\": -0.0183, \"times_seen\": 7.0}, {\"site\": 118, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"120\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 119, \"mutant\": \"-\", \"log2 fold change IC90\": 0.0006562612467180155, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.0874837331398643, \"functional effect\": -1.5307, \"times_seen\": 3.0}, {\"site\": 119, \"mutant\": \"D\", \"log2 fold change IC90\": 0.01024369627525955, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.08806704264577467, \"functional effect\": 0.0972, \"times_seen\": 10.0}, {\"site\": 119, \"mutant\": \"I\", \"log2 fold change IC90\": -0.021823494768351853, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.08613114612275252, \"functional effect\": -0.5188, \"times_seen\": 9.0}, {\"site\": 119, \"mutant\": \"K\", \"log2 fold change IC90\": -0.29021294543697873, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.07151002849838033, \"functional effect\": -0.6765, \"times_seen\": 19.0}, {\"site\": 119, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 119, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04384641935221856, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.08482632759398955, \"functional effect\": -0.1782, \"times_seen\": 49.0}, {\"site\": 119, \"mutant\": \"T\", \"log2 fold change IC90\": 1.5844772854069253, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": 0.26224362720300476, \"functional effect\": -0.2585, \"times_seen\": 15.0}, {\"site\": 119, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"121\", \"IC90\": null, \"functional effect\": -2.8939, \"times_seen\": null}, {\"site\": 120, \"mutant\": \"-\", \"log2 fold change IC90\": -0.00024259567813853102, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08742924423839105, \"functional effect\": -2.2739, \"times_seen\": 6.0}, {\"site\": 120, \"mutant\": \"D\", \"log2 fold change IC90\": -0.021448167149261177, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08615355668254245, \"functional effect\": -0.1638, \"times_seen\": 23.0}, {\"site\": 120, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": null, \"functional effect\": 0.3319, \"times_seen\": null}, {\"site\": 120, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0416862170718178, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08495343642658586, \"functional effect\": -0.2587, \"times_seen\": 15.0}, {\"site\": 120, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 120, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0034223402575000055, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08765162658943676, \"functional effect\": -0.2652, \"times_seen\": 16.0}, {\"site\": 120, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013436476205680505, \"epitope\": \"all\", \"reference_site\": \"122\", \"IC90\": 0.08663332249523627, \"functional effect\": -0.1114, \"times_seen\": 9.0}, {\"site\": 121, \"mutant\": \"-\", \"log2 fold change IC90\": -0.026010104391259694, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08588156130738965, \"functional effect\": -2.2622, \"times_seen\": 1.0}, {\"site\": 121, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 121, \"mutant\": \"D\", \"log2 fold change IC90\": -0.09925995379914516, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.081629949788849, \"functional effect\": -0.0998, \"times_seen\": 19.0}, {\"site\": 121, \"mutant\": \"E\", \"log2 fold change IC90\": -0.00849247500167187, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08693071728677443, \"functional effect\": -0.2161, \"times_seen\": 1.0}, {\"site\": 121, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": null, \"functional effect\": -1.6932, \"times_seen\": null}, {\"site\": 121, \"mutant\": \"L\", \"log2 fold change IC90\": -0.007208824154086952, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08700809909235867, \"functional effect\": -0.112, \"times_seen\": 3.0}, {\"site\": 121, \"mutant\": \"P\", \"log2 fold change IC90\": -0.00992926202827108, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08684418565729425, \"functional effect\": -0.0756, \"times_seen\": 1.0}, {\"site\": 121, \"mutant\": \"S\", \"log2 fold change IC90\": -1.2949437925996607, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.03563795938501936, \"functional effect\": 0.0374, \"times_seen\": 30.0}, {\"site\": 121, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08236886969774854, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08259129054947573, \"functional effect\": -0.2843, \"times_seen\": 47.0}, {\"site\": 121, \"mutant\": \"V\", \"log2 fold change IC90\": -0.014999607459957959, \"epitope\": \"all\", \"reference_site\": \"123\", \"IC90\": 0.08653950785341778, \"functional effect\": -0.024, \"times_seen\": 84.0}, {\"site\": 122, \"mutant\": \"-\", \"log2 fold change IC90\": 0.08638003833961376, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.09283948771961445, \"functional effect\": -1.2814, \"times_seen\": 6.0}, {\"site\": 122, \"mutant\": \"A\", \"log2 fold change IC90\": -0.016063628213346438, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08647570650761359, \"functional effect\": -0.1718, \"times_seen\": 7.0}, {\"site\": 122, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0656619562635006, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08355328596742248, \"functional effect\": -0.3737, \"times_seen\": 54.0}, {\"site\": 122, \"mutant\": \"L\", \"log2 fold change IC90\": 0.010228271089398906, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08806610104467373, \"functional effect\": -0.3962, \"times_seen\": 10.0}, {\"site\": 122, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0006228002926017923, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08748170412115211, \"functional effect\": -0.439, \"times_seen\": 11.0}, {\"site\": 122, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005928850289731114, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.08708532782590214, \"functional effect\": -0.0765, \"times_seen\": 14.0}, {\"site\": 122, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"124\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 123, \"mutant\": \"-\", \"log2 fold change IC90\": 0.008304070889750695, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08794872083070372, \"functional effect\": -2.1196, \"times_seen\": 6.0}, {\"site\": 123, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01308866614807691, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08665421088292947, \"functional effect\": -0.0348, \"times_seen\": 4.0}, {\"site\": 123, \"mutant\": \"G\", \"log2 fold change IC90\": 0.001403964635115877, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08752908495381799, \"functional effect\": -0.0677, \"times_seen\": 1.0}, {\"site\": 123, \"mutant\": \"H\", \"log2 fold change IC90\": -0.031351018718494536, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08556421213933693, \"functional effect\": -0.1177, \"times_seen\": 6.0}, {\"site\": 123, \"mutant\": \"I\", \"log2 fold change IC90\": 0.002812575192004744, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08761458784940282, \"functional effect\": -1.3304, \"times_seen\": 1.0}, {\"site\": 123, \"mutant\": \"K\", \"log2 fold change IC90\": -0.007659340410914874, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08698093296071231, \"functional effect\": -0.0595, \"times_seen\": 6.0}, {\"site\": 123, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01735186435593341, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08639852359291987, \"functional effect\": 0.0223, \"times_seen\": 8.0}, {\"site\": 123, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 123, \"mutant\": \"S\", \"log2 fold change IC90\": 0.5258739636427168, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.12590227851518132, \"functional effect\": 0.1075, \"times_seen\": 15.0}, {\"site\": 123, \"mutant\": \"T\", \"log2 fold change IC90\": 0.01932032536770386, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08862285775391693, \"functional effect\": -0.1681, \"times_seen\": 11.0}, {\"site\": 123, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.000321566929786063, \"epitope\": \"all\", \"reference_site\": \"125\", \"IC90\": 0.08742445860616316, \"functional effect\": 0.3921, \"times_seen\": 1.0}, {\"site\": 124, \"mutant\": \"-\", \"log2 fold change IC90\": -0.02425684758275865, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08598599360776846, \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 124, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0053544433198176285, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08776909107275646, \"functional effect\": -0.0382, \"times_seen\": 18.0}, {\"site\": 124, \"mutant\": \"E\", \"log2 fold change IC90\": -0.006455163823931297, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08705356378295812, \"functional effect\": -0.1827, \"times_seen\": 1.0}, {\"site\": 124, \"mutant\": \"F\", \"log2 fold change IC90\": -1.040400797387407, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.04251458119851984, \"functional effect\": -0.2101, \"times_seen\": 61.0}, {\"site\": 124, \"mutant\": \"G\", \"log2 fold change IC90\": -0.00729638113179662, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08700281874217461, \"functional effect\": -0.5421, \"times_seen\": 1.0}, {\"site\": 124, \"mutant\": \"I\", \"log2 fold change IC90\": -0.046621511980324534, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08466331694214141, \"functional effect\": -0.219, \"times_seen\": 27.0}, {\"site\": 124, \"mutant\": \"L\", \"log2 fold change IC90\": 0.07756829764337389, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.09227416780977543, \"functional effect\": -0.3493, \"times_seen\": 32.0}, {\"site\": 124, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05289418404735943, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.08429600966345797, \"functional effect\": -0.0396, \"times_seen\": 13.0}, {\"site\": 124, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"126\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 125, \"mutant\": \"A\", \"log2 fold change IC90\": 0.057220193986120924, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.09098184668216056, \"functional effect\": -0.4349, \"times_seen\": 11.0}, {\"site\": 125, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": null, \"functional effect\": -0.0781, \"times_seen\": null}, {\"site\": 125, \"mutant\": \"F\", \"log2 fold change IC90\": -0.028726213325500013, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.0857200273528074, \"functional effect\": -0.4226, \"times_seen\": 7.0}, {\"site\": 125, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": null, \"functional effect\": 0.2259, \"times_seen\": null}, {\"site\": 125, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03659137598783074, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.08969017152724258, \"functional effect\": -0.106, \"times_seen\": 35.0}, {\"site\": 125, \"mutant\": \"M\", \"log2 fold change IC90\": 0.015249510638404152, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.08837314543138199, \"functional effect\": -0.2638, \"times_seen\": 12.0}, {\"site\": 125, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"127\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"-\", \"log2 fold change IC90\": -0.007866178856135851, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08696846344303258, \"functional effect\": -2.3119, \"times_seen\": 2.0}, {\"site\": 126, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0302602936643963, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08929744005830619, \"functional effect\": -0.2409, \"times_seen\": 12.0}, {\"site\": 126, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"L\", \"log2 fold change IC90\": -0.036085053594565736, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08528390334622099, \"functional effect\": -0.4791, \"times_seen\": 18.0}, {\"site\": 126, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": 0.9989, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": -1.4896, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": -1.743, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": null, \"functional effect\": -0.388, \"times_seen\": null}, {\"site\": 126, \"mutant\": \"T\", \"log2 fold change IC90\": -0.010922523205778767, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08678441608101109, \"functional effect\": -0.3778, \"times_seen\": 3.0}, {\"site\": 126, \"mutant\": \"V\", \"log2 fold change IC90\": -0.028315141267814172, \"epitope\": \"all\", \"reference_site\": \"128\", \"IC90\": 0.08574445533489784, \"functional effect\": 0.0844, \"times_seen\": 32.0}, {\"site\": 127, \"mutant\": \"E\", \"log2 fold change IC90\": 0.01901847130943053, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08860431719604309, \"functional effect\": -0.3373, \"times_seen\": 3.0}, {\"site\": 127, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": null, \"functional effect\": -2.9735, \"times_seen\": null}, {\"site\": 127, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 127, \"mutant\": \"M\", \"log2 fold change IC90\": -0.012167644629479986, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08670954889385725, \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 127, \"mutant\": \"N\", \"log2 fold change IC90\": -0.12218814747886302, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08034289105646117, \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 127, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 127, \"mutant\": \"R\", \"log2 fold change IC90\": -0.2576614939008994, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.07314184554423206, \"functional effect\": -0.0909, \"times_seen\": 50.0}, {\"site\": 127, \"mutant\": \"T\", \"log2 fold change IC90\": 0.021625679736761765, \"epitope\": \"all\", \"reference_site\": \"129\", \"IC90\": 0.08876458584596392, \"functional effect\": -0.2494, \"times_seen\": 9.0}, {\"site\": 128, \"mutant\": \"A\", \"log2 fold change IC90\": 0.01461389240598125, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08833421883306089, \"functional effect\": -0.4587, \"times_seen\": 16.0}, {\"site\": 128, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0159481584560296, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08841595188427227, \"functional effect\": -0.4335, \"times_seen\": 29.0}, {\"site\": 128, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06341981858180741, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08368323971020167, \"functional effect\": -0.2335, \"times_seen\": 10.0}, {\"site\": 128, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0017508549524419016, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08733788947567656, \"functional effect\": -0.1666, \"times_seen\": 23.0}, {\"site\": 128, \"mutant\": \"M\", \"log2 fold change IC90\": 0.02469610030033915, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08895370054436705, \"functional effect\": -0.4105, \"times_seen\": 7.0}, {\"site\": 128, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01938737658736947, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08862697671781708, \"functional effect\": -0.8318, \"times_seen\": 10.0}, {\"site\": 128, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 128, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.026609241186729506, \"epitope\": \"all\", \"reference_site\": \"130\", \"IC90\": 0.08584590296025436, \"functional effect\": -0.3397, \"times_seen\": 9.0}, {\"site\": 129, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": null, \"functional effect\": -3.2644, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": null, \"functional effect\": -2.2294, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": null, \"functional effect\": -3.2541, \"times_seen\": null}, {\"site\": 129, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00501160977629109, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08714071277317838, \"functional effect\": -2.8472, \"times_seen\": 1.0}, {\"site\": 129, \"mutant\": \"S\", \"log2 fold change IC90\": 0.022663997250508026, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08882849332163761, \"functional effect\": -2.2664, \"times_seen\": 2.0}, {\"site\": 129, \"mutant\": \"V\", \"log2 fold change IC90\": -0.009733966062606923, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08685594245039381, \"functional effect\": -1.8136, \"times_seen\": 3.0}, {\"site\": 129, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02190405945251086, \"epitope\": \"all\", \"reference_site\": \"131\", \"IC90\": 0.08612633641963505, \"functional effect\": -2.3392, \"times_seen\": 2.0}, {\"site\": 130, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": null, \"functional effect\": -2.9703, \"times_seen\": null}, {\"site\": 130, \"mutant\": \"A\", \"log2 fold change IC90\": 0.06229406704173023, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.09130238778273424, \"functional effect\": 0.0898, \"times_seen\": 42.0}, {\"site\": 130, \"mutant\": \"D\", \"log2 fold change IC90\": -0.1355711420743761, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.07960104561100644, \"functional effect\": -0.0837, \"times_seen\": 81.0}, {\"site\": 130, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 130, \"mutant\": \"G\", \"log2 fold change IC90\": -0.017440924102480052, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.08639319024602436, \"functional effect\": -0.2183, \"times_seen\": 15.0}, {\"site\": 130, \"mutant\": \"K\", \"log2 fold change IC90\": 0.14795171796636855, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.09688747946320753, \"functional effect\": 0.3539, \"times_seen\": 41.0}, {\"site\": 130, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01661875663832536, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.08845705922652092, \"functional effect\": -0.1598, \"times_seen\": 9.0}, {\"site\": 130, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.14106012375397306, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.07929876513134501, \"functional effect\": 0.2681, \"times_seen\": 59.0}, {\"site\": 130, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03440535763613706, \"epitope\": \"all\", \"reference_site\": \"132\", \"IC90\": 0.08538325521753429, \"functional effect\": 0.3141, \"times_seen\": 16.0}, {\"site\": 131, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": null, \"functional effect\": -3.2642, \"times_seen\": null}, {\"site\": 131, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 131, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0021634459712666252, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.08757517522606774, \"functional effect\": -0.1434, \"times_seen\": 24.0}, {\"site\": 131, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06745089654574435, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.08344974419277086, \"functional effect\": -0.2888, \"times_seen\": 16.0}, {\"site\": 131, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03039252068671299, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.08562107819667102, \"functional effect\": -1.5164, \"times_seen\": 8.0}, {\"site\": 131, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.1859623377135552, \"epitope\": \"all\", \"reference_site\": \"133\", \"IC90\": 0.09947409450690785, \"functional effect\": -0.1178, \"times_seen\": 18.0}, {\"site\": 132, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006517436587317784, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.0870498062674545, \"functional effect\": -2.8438, \"times_seen\": 1.0}, {\"site\": 132, \"mutant\": \"E\", \"log2 fold change IC90\": 0.2053579665701678, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.10082045675132723, \"functional effect\": 0.125, \"times_seen\": 41.0}, {\"site\": 132, \"mutant\": \"H\", \"log2 fold change IC90\": -0.3927660161877906, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.06660324677507232, \"functional effect\": -0.0731, \"times_seen\": 137.0}, {\"site\": 132, \"mutant\": \"K\", \"log2 fold change IC90\": -0.10628218948311366, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08123358609350669, \"functional effect\": -0.0553, \"times_seen\": 29.0}, {\"site\": 132, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01323999837035491, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08664512172258888, \"functional effect\": -0.1193, \"times_seen\": 144.0}, {\"site\": 132, \"mutant\": \"N\", \"log2 fold change IC90\": -0.11234406497514089, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08089297717522821, \"functional effect\": 0.0087, \"times_seen\": 9.0}, {\"site\": 132, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": null, \"functional effect\": -0.5534, \"times_seen\": null}, {\"site\": 132, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 132, \"mutant\": \"R\", \"log2 fold change IC90\": 0.049205652566715406, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.0904778204545485, \"functional effect\": -0.0991, \"times_seen\": 47.0}, {\"site\": 132, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03757740260941669, \"epitope\": \"all\", \"reference_site\": \"134\", \"IC90\": 0.08519572979509821, \"functional effect\": -0.0935, \"times_seen\": 10.0}, {\"site\": 133, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 133, \"mutant\": \"I\", \"log2 fold change IC90\": -0.07069620160183022, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08326223713395557, \"functional effect\": -0.0108, \"times_seen\": 37.0}, {\"site\": 133, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03996124921636603, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08505507231271571, \"functional effect\": -0.0847, \"times_seen\": 42.0}, {\"site\": 133, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 133, \"mutant\": \"S\", \"log2 fold change IC90\": -0.023768617565750515, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08601509750445405, \"functional effect\": -0.3028, \"times_seen\": 4.0}, {\"site\": 133, \"mutant\": \"V\", \"log2 fold change IC90\": 0.05127511342091171, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.09060769867490046, \"functional effect\": -0.068, \"times_seen\": 12.0}, {\"site\": 133, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.10355252379709098, \"epitope\": \"all\", \"reference_site\": \"135\", \"IC90\": 0.08138743041388587, \"functional effect\": -0.0252, \"times_seen\": 26.0}, {\"site\": 134, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": null, \"functional effect\": 0.2867, \"times_seen\": null}, {\"site\": 134, \"mutant\": \"-\", \"log2 fold change IC90\": 0.06654105876760394, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.09157155886720247, \"functional effect\": -0.1883, \"times_seen\": 17.0}, {\"site\": 134, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 134, \"mutant\": \"F\", \"log2 fold change IC90\": 0.06964832294051741, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.0917689974476752, \"functional effect\": -0.0199, \"times_seen\": 87.0}, {\"site\": 134, \"mutant\": \"G\", \"log2 fold change IC90\": 0.03420480322705041, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08954192455587988, \"functional effect\": -0.1983, \"times_seen\": 13.0}, {\"site\": 134, \"mutant\": \"L\", \"log2 fold change IC90\": -1.2698448829244458, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.03626338603713816, \"functional effect\": -0.0987, \"times_seen\": 16.0}, {\"site\": 134, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0303286388938172, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08930167047320171, \"functional effect\": -0.0854, \"times_seen\": 15.0}, {\"site\": 134, \"mutant\": \"S\", \"log2 fold change IC90\": -0.050653997732789946, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08442700439914326, \"functional effect\": -0.2441, \"times_seen\": 16.0}, {\"site\": 134, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005583988228502351, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08710614720530636, \"functional effect\": -0.1774, \"times_seen\": 6.0}, {\"site\": 134, \"mutant\": \"W\", \"log2 fold change IC90\": -0.02797203786768318, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08576484960525087, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 134, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06280340198618019, \"epitope\": \"all\", \"reference_site\": \"136\", \"IC90\": 0.08371900247216174, \"functional effect\": -0.0384, \"times_seen\": 43.0}, {\"site\": 135, \"mutant\": \"-\", \"log2 fold change IC90\": 0.006122503721685405, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.0878158299253817, \"functional effect\": 0.1167, \"times_seen\": 7.0}, {\"site\": 135, \"mutant\": \"D\", \"log2 fold change IC90\": -0.049618161252420544, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08448764366872626, \"functional effect\": 0.2205, \"times_seen\": 24.0}, {\"site\": 135, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 135, \"mutant\": \"I\", \"log2 fold change IC90\": -0.08592561715276172, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.0823879249417099, \"functional effect\": 0.0149, \"times_seen\": 18.0}, {\"site\": 135, \"mutant\": \"K\", \"log2 fold change IC90\": -0.030172119733665795, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08563415955360068, \"functional effect\": -0.073, \"times_seen\": 13.0}, {\"site\": 135, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00034497242182764375, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08742304029126366, \"functional effect\": -0.0814, \"times_seen\": 13.0}, {\"site\": 135, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 135, \"mutant\": \"S\", \"log2 fold change IC90\": -6.608964415398025, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.0008958457207649633, \"functional effect\": -0.0079, \"times_seen\": 28.0}, {\"site\": 135, \"mutant\": \"T\", \"log2 fold change IC90\": -0.024669841897725146, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08596138227750932, \"functional effect\": 0.2271, \"times_seen\": 9.0}, {\"site\": 135, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0662183176542673, \"epitope\": \"all\", \"reference_site\": \"137\", \"IC90\": 0.08352107066286062, \"functional effect\": -0.0102, \"times_seen\": 26.0}, {\"site\": 136, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0005084783164430481, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08741313288045792, \"functional effect\": -2.988, \"times_seen\": 1.0}, {\"site\": 136, \"mutant\": \"-\", \"log2 fold change IC90\": -0.005382995380603639, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08711828347230885, \"functional effect\": -0.0355, \"times_seen\": 2.0}, {\"site\": 136, \"mutant\": \"A\", \"log2 fold change IC90\": -0.8280793889399034, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.04925530560082415, \"functional effect\": 0.0073, \"times_seen\": 185.0}, {\"site\": 136, \"mutant\": \"C\", \"log2 fold change IC90\": -0.07173798580807365, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08320213436078637, \"functional effect\": -0.1698, \"times_seen\": 32.0}, {\"site\": 136, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 136, \"mutant\": \"E\", \"log2 fold change IC90\": 0.07438963807334953, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.09207108588629352, \"functional effect\": 0.0292, \"times_seen\": 71.0}, {\"site\": 136, \"mutant\": \"F\", \"log2 fold change IC90\": 0.07787995446736377, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.09229410340231624, \"functional effect\": -0.0714, \"times_seen\": 35.0}, {\"site\": 136, \"mutant\": \"G\", \"log2 fold change IC90\": -0.2934645852765413, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.0713490360447087, \"functional effect\": 0.0135, \"times_seen\": 127.0}, {\"site\": 136, \"mutant\": \"H\", \"log2 fold change IC90\": 0.5591896629646874, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.12884352991572845, \"functional effect\": 0.0006, \"times_seen\": 106.0}, {\"site\": 136, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0817255350110591, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08262812833511624, \"functional effect\": -0.0646, \"times_seen\": 50.0}, {\"site\": 136, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03999264731649448, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08505322123640299, \"functional effect\": -0.0658, \"times_seen\": 32.0}, {\"site\": 136, \"mutant\": \"L\", \"log2 fold change IC90\": 1.1397632130648834, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.19267823878851686, \"functional effect\": -0.0911, \"times_seen\": 81.0}, {\"site\": 136, \"mutant\": \"M\", \"log2 fold change IC90\": -0.10720311130186301, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08118174845077442, \"functional effect\": -0.0307, \"times_seen\": 23.0}, {\"site\": 136, \"mutant\": \"N\", \"log2 fold change IC90\": -0.01231152998328459, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08670090145858003, \"functional effect\": -0.0782, \"times_seen\": 125.0}, {\"site\": 136, \"mutant\": \"P\", \"log2 fold change IC90\": 0.666374185945642, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.13878047548741004, \"functional effect\": -0.0112, \"times_seen\": 104.0}, {\"site\": 136, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06379808487847599, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08366130132487132, \"functional effect\": 0.099, \"times_seen\": 39.0}, {\"site\": 136, \"mutant\": \"R\", \"log2 fold change IC90\": -1.1488574676578225, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.039435667326792906, \"functional effect\": -0.1031, \"times_seen\": 85.0}, {\"site\": 136, \"mutant\": \"S\", \"log2 fold change IC90\": 0.038697793971587104, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08982121999746907, \"functional effect\": -0.0089, \"times_seen\": 115.0}, {\"site\": 136, \"mutant\": \"T\", \"log2 fold change IC90\": 0.014581156586847301, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08833221448694335, \"functional effect\": -0.0597, \"times_seen\": 94.0}, {\"site\": 136, \"mutant\": \"V\", \"log2 fold change IC90\": -0.007300054248874374, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.08700259723234512, \"functional effect\": -0.0432, \"times_seen\": 76.0}, {\"site\": 136, \"mutant\": \"W\", \"log2 fold change IC90\": 0.14329689125983636, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.09657537771351062, \"functional effect\": -0.0004, \"times_seen\": 22.0}, {\"site\": 136, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.25937891820117537, \"epitope\": \"all\", \"reference_site\": \"138\", \"IC90\": 0.07305482726187526, \"functional effect\": -0.1254, \"times_seen\": 108.0}, {\"site\": 137, \"mutant\": \"-\", \"log2 fold change IC90\": -0.013560774695110628, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08662585873682463, \"functional effect\": 0.0539, \"times_seen\": 7.0}, {\"site\": 137, \"mutant\": \"A\", \"log2 fold change IC90\": -0.010301014635757152, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08682181059369766, \"functional effect\": 0.1536, \"times_seen\": 2.0}, {\"site\": 137, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0023609120386804973, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08758716272758413, \"functional effect\": -0.1663, \"times_seen\": 14.0}, {\"site\": 137, \"mutant\": \"L\", \"log2 fold change IC90\": -1.2125390406700147, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.0377328084291359, \"functional effect\": -0.0056, \"times_seen\": 52.0}, {\"site\": 137, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 137, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016373481303098583, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08645713578622767, \"functional effect\": -0.0651, \"times_seen\": 13.0}, {\"site\": 137, \"mutant\": \"S\", \"log2 fold change IC90\": -0.038224088970911, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.08515754946683492, \"functional effect\": -0.0358, \"times_seen\": 34.0}, {\"site\": 137, \"mutant\": \"T\", \"log2 fold change IC90\": -0.027585617205354677, \"epitope\": \"all\", \"reference_site\": \"139\", \"IC90\": 0.0857878244875621, \"functional effect\": -0.1179, \"times_seen\": 16.0}, {\"site\": 138, \"mutant\": \"-\", \"log2 fold change IC90\": -0.06021181609246348, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08386952629667252, \"functional effect\": 0.0078, \"times_seen\": 34.0}, {\"site\": 138, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01704195547573403, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08641708506642491, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 138, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 138, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03595957230363136, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08965090184589512, \"functional effect\": -0.0353, \"times_seen\": 20.0}, {\"site\": 138, \"mutant\": \"L\", \"log2 fold change IC90\": -0.039191632070892386, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08510045772213866, \"functional effect\": -0.0265, \"times_seen\": 28.0}, {\"site\": 138, \"mutant\": \"S\", \"log2 fold change IC90\": 0.059510250066777126, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.09112638102754127, \"functional effect\": -0.134, \"times_seen\": 10.0}, {\"site\": 138, \"mutant\": \"V\", \"log2 fold change IC90\": 0.028749888170884558, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08920400051489114, \"functional effect\": 0.2253, \"times_seen\": 3.0}, {\"site\": 138, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04324106710321748, \"epitope\": \"all\", \"reference_site\": \"140\", \"IC90\": 0.08486192803717295, \"functional effect\": 0.0353, \"times_seen\": 32.0}, {\"site\": 139, \"mutant\": \"-\", \"log2 fold change IC90\": 0.03836520607020889, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08980051568569318, \"functional effect\": -0.0929, \"times_seen\": 18.0}, {\"site\": 139, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0008304808535176616, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08739362487021858, \"functional effect\": -0.1315, \"times_seen\": 42.0}, {\"site\": 139, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0021107441317923872, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08731610521749551, \"functional effect\": 0.191, \"times_seen\": 11.0}, {\"site\": 139, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 139, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03157791089232994, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08555075654198632, \"functional effect\": 0.1949, \"times_seen\": 25.0}, {\"site\": 139, \"mutant\": \"P\", \"log2 fold change IC90\": 0.020379205444989272, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08868792723983325, \"functional effect\": 0.144, \"times_seen\": 27.0}, {\"site\": 139, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010007430068777481, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08683948039684235, \"functional effect\": -0.1531, \"times_seen\": 4.0}, {\"site\": 139, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01015973859892154, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08683031304331473, \"functional effect\": -0.2015, \"times_seen\": 2.0}, {\"site\": 139, \"mutant\": \"S\", \"log2 fold change IC90\": -0.021479281358122337, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.08615169865241473, \"functional effect\": 0.0782, \"times_seen\": 10.0}, {\"site\": 139, \"mutant\": \"V\", \"log2 fold change IC90\": -0.21171580547040952, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.07550869157539622, \"functional effect\": -0.0493, \"times_seen\": 16.0}, {\"site\": 139, \"mutant\": \"W\", \"log2 fold change IC90\": -0.010890170898586455, \"epitope\": \"all\", \"reference_site\": \"141\", \"IC90\": 0.0867863622355969, \"functional effect\": 0.2301, \"times_seen\": 15.0}, {\"site\": 140, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": null, \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 140, \"mutant\": \"-\", \"log2 fold change IC90\": 0.019672179309549228, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08864447431440675, \"functional effect\": 0.0809, \"times_seen\": 14.0}, {\"site\": 140, \"mutant\": \"A\", \"log2 fold change IC90\": -0.16825091946709778, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.07781819969117312, \"functional effect\": -0.0645, \"times_seen\": 145.0}, {\"site\": 140, \"mutant\": \"C\", \"log2 fold change IC90\": -0.24182469067020432, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.07394916376261575, \"functional effect\": -0.1518, \"times_seen\": 140.0}, {\"site\": 140, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 140, \"mutant\": \"E\", \"log2 fold change IC90\": 0.3632098037846561, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.11247779618493085, \"functional effect\": -0.0027, \"times_seen\": 66.0}, {\"site\": 140, \"mutant\": \"F\", \"log2 fold change IC90\": -0.012252968599511888, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08670442086335357, \"functional effect\": -0.0629, \"times_seen\": 32.0}, {\"site\": 140, \"mutant\": \"G\", \"log2 fold change IC90\": -0.6488020637463253, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.0557725973723427, \"functional effect\": -0.1234, \"times_seen\": 121.0}, {\"site\": 140, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0648372749900583, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08360106080961054, \"functional effect\": -0.1008, \"times_seen\": 77.0}, {\"site\": 140, \"mutant\": \"I\", \"log2 fold change IC90\": 0.030783627611812154, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.0893298383528357, \"functional effect\": 0.0047, \"times_seen\": 50.0}, {\"site\": 140, \"mutant\": \"K\", \"log2 fold change IC90\": 0.11538539475966562, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.0947249135753807, \"functional effect\": -0.3408, \"times_seen\": 40.0}, {\"site\": 140, \"mutant\": \"L\", \"log2 fold change IC90\": -0.6232271174774953, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.05677010485225504, \"functional effect\": 0.0144, \"times_seen\": 134.0}, {\"site\": 140, \"mutant\": \"M\", \"log2 fold change IC90\": -0.019547555756719553, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08626713046827858, \"functional effect\": 0.0018, \"times_seen\": 49.0}, {\"site\": 140, \"mutant\": \"N\", \"log2 fold change IC90\": -0.008531718703254488, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08692835265902407, \"functional effect\": -0.0348, \"times_seen\": 83.0}, {\"site\": 140, \"mutant\": \"P\", \"log2 fold change IC90\": 0.573222574146934, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.1301028894307493, \"functional effect\": 0.0264, \"times_seen\": 131.0}, {\"site\": 140, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.4616979320191132, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.06349577470623502, \"functional effect\": 0.0365, \"times_seen\": 41.0}, {\"site\": 140, \"mutant\": \"R\", \"log2 fold change IC90\": 0.38610649078106885, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.11427714664608062, \"functional effect\": -0.3689, \"times_seen\": 113.0}, {\"site\": 140, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01926333597806336, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08628412729669353, \"functional effect\": -0.1074, \"times_seen\": 207.0}, {\"site\": 140, \"mutant\": \"T\", \"log2 fold change IC90\": 0.3152839590300232, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.1088027022263115, \"functional effect\": 0.0065, \"times_seen\": 93.0}, {\"site\": 140, \"mutant\": \"V\", \"log2 fold change IC90\": -0.6466082974836922, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.05585746985795388, \"functional effect\": -0.0163, \"times_seen\": 89.0}, {\"site\": 140, \"mutant\": \"W\", \"log2 fold change IC90\": 0.14403228763564924, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.0966246183949582, \"functional effect\": 0.0605, \"times_seen\": 32.0}, {\"site\": 140, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.018817566767510886, \"epitope\": \"all\", \"reference_site\": \"142\", \"IC90\": 0.08859197933540101, \"functional effect\": -0.1328, \"times_seen\": 82.0}, {\"site\": 141, \"mutant\": \"-\", \"log2 fold change IC90\": -0.01028053170397088, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08682304327128922, \"functional effect\": -0.0301, \"times_seen\": 14.0}, {\"site\": 141, \"mutant\": \"D\", \"log2 fold change IC90\": -0.20815385750653745, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.07569534940572432, \"functional effect\": 0.168, \"times_seen\": 10.0}, {\"site\": 141, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 141, \"mutant\": \"K\", \"log2 fold change IC90\": -0.006223907399071927, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08706751912968752, \"functional effect\": -0.1113, \"times_seen\": 14.0}, {\"site\": 141, \"mutant\": \"L\", \"log2 fold change IC90\": -0.016409628562005837, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08645496959778727, \"functional effect\": -0.0101, \"times_seen\": 33.0}, {\"site\": 141, \"mutant\": \"N\", \"log2 fold change IC90\": -0.018224750733971857, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08634626495061387, \"functional effect\": -0.0471, \"times_seen\": 80.0}, {\"site\": 141, \"mutant\": \"P\", \"log2 fold change IC90\": 0.03095185059175805, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08934025511267199, \"functional effect\": 0.1253, \"times_seen\": 19.0}, {\"site\": 141, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013557245438618212, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08662607064941852, \"functional effect\": 0.0047, \"times_seen\": 46.0}, {\"site\": 141, \"mutant\": \"R\", \"log2 fold change IC90\": -0.04560781098512645, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.0847228260170878, \"functional effect\": 0.0445, \"times_seen\": 11.0}, {\"site\": 141, \"mutant\": \"S\", \"log2 fold change IC90\": 0.022788170023835107, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08883613911977704, \"functional effect\": -0.0282, \"times_seen\": 8.0}, {\"site\": 141, \"mutant\": \"T\", \"log2 fold change IC90\": 0.17470183029856176, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.09870070256346594, \"functional effect\": -0.06, \"times_seen\": 15.0}, {\"site\": 141, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.013993604129642552, \"epitope\": \"all\", \"reference_site\": \"146\", \"IC90\": 0.08659987362108795, \"functional effect\": -0.0143, \"times_seen\": 87.0}, {\"site\": 142, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": null, \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": null, \"functional effect\": 0.8951, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"A\", \"log2 fold change IC90\": 2.7163042009015814e-05, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08744559350519424, \"functional effect\": 0.0112, \"times_seen\": 1.0}, {\"site\": 142, \"mutant\": \"E\", \"log2 fold change IC90\": -0.4785079393707563, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.06276022760329646, \"functional effect\": 0.0494, \"times_seen\": 76.0}, {\"site\": 142, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": null, \"functional effect\": -2.9356, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"I\", \"log2 fold change IC90\": -0.07244887811503926, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08316114635892863, \"functional effect\": 0.0829, \"times_seen\": 21.0}, {\"site\": 142, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 142, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02052745335380318, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08620855658398204, \"functional effect\": 0.2134, \"times_seen\": 5.0}, {\"site\": 142, \"mutant\": \"N\", \"log2 fold change IC90\": -0.1393102176675756, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.07939500832832472, \"functional effect\": 0.0867, \"times_seen\": 79.0}, {\"site\": 142, \"mutant\": \"P\", \"log2 fold change IC90\": -0.017593945839916577, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08638402730124241, \"functional effect\": 0.1616, \"times_seen\": 4.0}, {\"site\": 142, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.00406747672268307, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08769083092858976, \"functional effect\": -0.0244, \"times_seen\": 39.0}, {\"site\": 142, \"mutant\": \"R\", \"log2 fold change IC90\": -0.015162966807932379, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08652970936044214, \"functional effect\": 0.0635, \"times_seen\": 62.0}, {\"site\": 142, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04272329875604529, \"epitope\": \"all\", \"reference_site\": \"147\", \"IC90\": 0.08489238957236214, \"functional effect\": -0.0491, \"times_seen\": 11.0}, {\"site\": 143, \"mutant\": \"-\", \"log2 fold change IC90\": 0.01430823023714195, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.08831550554433883, \"functional effect\": -0.0551, \"times_seen\": 17.0}, {\"site\": 143, \"mutant\": \"D\", \"log2 fold change IC90\": 0.08919715445229098, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09302095027870917, \"functional effect\": 0.0116, \"times_seen\": 62.0}, {\"site\": 143, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": null, \"functional effect\": -0.2116, \"times_seen\": null}, {\"site\": 143, \"mutant\": \"H\", \"log2 fold change IC90\": 0.11570066961809745, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09474561625076848, \"functional effect\": -0.0741, \"times_seen\": 21.0}, {\"site\": 143, \"mutant\": \"K\", \"log2 fold change IC90\": -0.058157661635881534, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.08398902741373292, \"functional effect\": -0.1002, \"times_seen\": 46.0}, {\"site\": 143, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 143, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.054597293596144146, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09081658686030679, \"functional effect\": -0.0122, \"times_seen\": 17.0}, {\"site\": 143, \"mutant\": \"S\", \"log2 fold change IC90\": 0.32177117753514806, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.10929304576678649, \"functional effect\": 0.0886, \"times_seen\": 75.0}, {\"site\": 143, \"mutant\": \"T\", \"log2 fold change IC90\": 0.007606608361456286, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.08790621280899286, \"functional effect\": 0.0449, \"times_seen\": 108.0}, {\"site\": 143, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.1402947977017215, \"epitope\": \"all\", \"reference_site\": \"148\", \"IC90\": 0.09637462366267767, \"functional effect\": 0.0044, \"times_seen\": 52.0}, {\"site\": 144, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0017863256825495547, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08733574217459446, \"functional effect\": -0.0678, \"times_seen\": 14.0}, {\"site\": 144, \"mutant\": \"H\", \"log2 fold change IC90\": -0.003219375889201226, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08724903336884941, \"functional effect\": 0.0107, \"times_seen\": 26.0}, {\"site\": 144, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06926106320211617, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08334510446457931, \"functional effect\": -0.1116, \"times_seen\": 25.0}, {\"site\": 144, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0027847819757814375, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08727532001259597, \"functional effect\": 0.0619, \"times_seen\": 11.0}, {\"site\": 144, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 144, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03776236263219003, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08518480801772403, \"functional effect\": -0.1299, \"times_seen\": 13.0}, {\"site\": 144, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": null, \"functional effect\": 0.2256, \"times_seen\": null}, {\"site\": 144, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0328671949485537, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08945894339254042, \"functional effect\": 0.0286, \"times_seen\": 21.0}, {\"site\": 144, \"mutant\": \"T\", \"log2 fold change IC90\": -0.030617755342584926, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08560771201169548, \"functional effect\": 0.0276, \"times_seen\": 16.0}, {\"site\": 144, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05510390022471857, \"epitope\": \"all\", \"reference_site\": \"149\", \"IC90\": 0.08416699578834658, \"functional effect\": -0.0154, \"times_seen\": 23.0}, {\"site\": 145, \"mutant\": \"-\", \"log2 fold change IC90\": 0.012490529844875564, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08820430391289419, \"functional effect\": 0.1374, \"times_seen\": 33.0}, {\"site\": 145, \"mutant\": \"E\", \"log2 fold change IC90\": 0.018566688723589398, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08857657493635329, \"functional effect\": 0.0949, \"times_seen\": 50.0}, {\"site\": 145, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 145, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0643753919943605, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.0836278302162784, \"functional effect\": 0.0173, \"times_seen\": 53.0}, {\"site\": 145, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 145, \"mutant\": \"N\", \"log2 fold change IC90\": -0.10718928565055329, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.0811825264363452, \"functional effect\": 0.0648, \"times_seen\": 66.0}, {\"site\": 145, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.029117727829522287, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08569676805014145, \"functional effect\": 0.1539, \"times_seen\": 11.0}, {\"site\": 145, \"mutant\": \"R\", \"log2 fold change IC90\": -0.04139834900898866, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08497038929638534, \"functional effect\": 0.0102, \"times_seen\": 23.0}, {\"site\": 145, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011754022052985237, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08673441220021809, \"functional effect\": 0.0316, \"times_seen\": 23.0}, {\"site\": 145, \"mutant\": \"V\", \"log2 fold change IC90\": 0.000716133277889768, \"epitope\": \"all\", \"reference_site\": \"150\", \"IC90\": 0.08748736380146353, \"functional effect\": -0.1884, \"times_seen\": 11.0}, {\"site\": 146, \"mutant\": \"-\", \"log2 fold change IC90\": 0.00829241116343208, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08794801004024415, \"functional effect\": 0.1256, \"times_seen\": 13.0}, {\"site\": 146, \"mutant\": \"C\", \"log2 fold change IC90\": 0.11860416834255842, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.09493648873191284, \"functional effect\": -0.3201, \"times_seen\": 14.0}, {\"site\": 146, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0034472203254097295, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08723525524070865, \"functional effect\": -0.7801, \"times_seen\": 1.0}, {\"site\": 146, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0074735444573410335, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08789810534059042, \"functional effect\": -0.1226, \"times_seen\": 28.0}, {\"site\": 146, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0669112598294269, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.09159505949426294, \"functional effect\": -0.2093, \"times_seen\": 34.0}, {\"site\": 146, \"mutant\": \"K\", \"log2 fold change IC90\": -0.018055991065365252, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08635636592063667, \"functional effect\": -0.205, \"times_seen\": 6.0}, {\"site\": 146, \"mutant\": \"N\", \"log2 fold change IC90\": 1.0984273966563045, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.1872359968675315, \"functional effect\": -0.0894, \"times_seen\": 44.0}, {\"site\": 146, \"mutant\": \"P\", \"log2 fold change IC90\": -0.016842334892182398, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08642904311852184, \"functional effect\": -0.3216, \"times_seen\": 4.0}, {\"site\": 146, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03310948734987239, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08947396877338426, \"functional effect\": 0.0198, \"times_seen\": 6.0}, {\"site\": 146, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0250394734254293, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08897487476654406, \"functional effect\": -0.1366, \"times_seen\": 9.0}, {\"site\": 146, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 146, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05292356712200804, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08429429284136357, \"functional effect\": 0.0105, \"times_seen\": 51.0}, {\"site\": 146, \"mutant\": \"V\", \"log2 fold change IC90\": -0.012729460252399094, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.08667578895582558, \"functional effect\": -0.2935, \"times_seen\": 9.0}, {\"site\": 146, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018381068571125828, \"epitope\": \"all\", \"reference_site\": \"151\", \"IC90\": 0.0863369097301454, \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 147, \"mutant\": \"*\", \"log2 fold change IC90\": 0.4926563349599999, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.12303653367736651, \"functional effect\": -2.6709, \"times_seen\": 6.0}, {\"site\": 147, \"mutant\": \"-\", \"log2 fold change IC90\": -0.01515156832025775, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08653039301963138, \"functional effect\": 0.1988, \"times_seen\": 6.0}, {\"site\": 147, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02807543626032325, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08575870303264459, \"functional effect\": -0.1035, \"times_seen\": 58.0}, {\"site\": 147, \"mutant\": \"F\", \"log2 fold change IC90\": 0.003899315354854504, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08768061023032916, \"functional effect\": 0.2968, \"times_seen\": 8.0}, {\"site\": 147, \"mutant\": \"G\", \"log2 fold change IC90\": 0.10662368927303667, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.09415137817517098, \"functional effect\": 0.056, \"times_seen\": 16.0}, {\"site\": 147, \"mutant\": \"K\", \"log2 fold change IC90\": -0.031843489804158936, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08553500935698852, \"functional effect\": -0.1747, \"times_seen\": 15.0}, {\"site\": 147, \"mutant\": \"L\", \"log2 fold change IC90\": -0.028488147054825528, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08573417360720093, \"functional effect\": -0.0578, \"times_seen\": 68.0}, {\"site\": 147, \"mutant\": \"R\", \"log2 fold change IC90\": 0.7652965820582138, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.14863017173610157, \"functional effect\": 0.0097, \"times_seen\": 66.0}, {\"site\": 147, \"mutant\": \"S\", \"log2 fold change IC90\": 0.21657613830593853, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.10160747681323781, \"functional effect\": -0.0447, \"times_seen\": 47.0}, {\"site\": 147, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": null, \"functional effect\": -0.7731, \"times_seen\": null}, {\"site\": 147, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 147, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.005030686696974302, \"epitope\": \"all\", \"reference_site\": \"152\", \"IC90\": 0.08774939693398334, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 148, \"mutant\": \"-\", \"log2 fold change IC90\": -0.022869798710827668, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08606870279002889, \"functional effect\": -0.0214, \"times_seen\": 13.0}, {\"site\": 148, \"mutant\": \"I\", \"log2 fold change IC90\": -0.2078732397638448, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.07571007429452344, \"functional effect\": 0.0462, \"times_seen\": 82.0}, {\"site\": 148, \"mutant\": \"K\", \"log2 fold change IC90\": 0.017365908130834506, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08850288175911422, \"functional effect\": -0.2152, \"times_seen\": 13.0}, {\"site\": 148, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03742279089615687, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.0897418742327761, \"functional effect\": 0.0377, \"times_seen\": 60.0}, {\"site\": 148, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 148, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01300512785574308, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08665922868238307, \"functional effect\": 0.0217, \"times_seen\": 15.0}, {\"site\": 148, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08220723502671068, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.08260054431659283, \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 148, \"mutant\": \"V\", \"log2 fold change IC90\": -0.524367194777243, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.06079662884684142, \"functional effect\": 0.0424, \"times_seen\": 41.0}, {\"site\": 148, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0435654855189681, \"epitope\": \"all\", \"reference_site\": \"153\", \"IC90\": 0.09012479102983428, \"functional effect\": 0.1417, \"times_seen\": 11.0}, {\"site\": 149, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": null, \"functional effect\": -2.9301, \"times_seen\": null}, {\"site\": 149, \"mutant\": \"-\", \"log2 fold change IC90\": -0.10687671286804236, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08120011726224231, \"functional effect\": -0.0626, \"times_seen\": 31.0}, {\"site\": 149, \"mutant\": \"A\", \"log2 fold change IC90\": -0.8912913084061489, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.047143772693864036, \"functional effect\": 0.0613, \"times_seen\": 38.0}, {\"site\": 149, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0005748652095997055, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08740911058008707, \"functional effect\": 0.0981, \"times_seen\": 17.0}, {\"site\": 149, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 149, \"mutant\": \"G\", \"log2 fold change IC90\": -0.017134470425788004, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08641154362090377, \"functional effect\": -0.1528, \"times_seen\": 52.0}, {\"site\": 149, \"mutant\": \"K\", \"log2 fold change IC90\": 0.054450761183249693, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.09080736322160707, \"functional effect\": -0.1484, \"times_seen\": 73.0}, {\"site\": 149, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03100613561822508, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08934361682753254, \"functional effect\": -0.0372, \"times_seen\": 72.0}, {\"site\": 149, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0023725947722560634, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.08758787199849787, \"functional effect\": -0.1094, \"times_seen\": 14.0}, {\"site\": 149, \"mutant\": \"V\", \"log2 fold change IC90\": 0.06760512338154291, \"epitope\": \"all\", \"reference_site\": \"154\", \"IC90\": 0.09163912269350732, \"functional effect\": 0.0753, \"times_seen\": 14.0}, {\"site\": 150, \"mutant\": \"-\", \"log2 fold change IC90\": -0.009527595552583208, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08686836765925764, \"functional effect\": -0.0872, \"times_seen\": 18.0}, {\"site\": 150, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": null, \"functional effect\": -3.1878, \"times_seen\": null}, {\"site\": 150, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": null, \"functional effect\": -0.2891, \"times_seen\": null}, {\"site\": 150, \"mutant\": \"G\", \"log2 fold change IC90\": -0.008412816091789305, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.0869355173291669, \"functional effect\": -0.0684, \"times_seen\": 19.0}, {\"site\": 150, \"mutant\": \"I\", \"log2 fold change IC90\": -0.050884063291898915, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.0844135419578391, \"functional effect\": -0.1026, \"times_seen\": 54.0}, {\"site\": 150, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0009453115753728886, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08750126264850595, \"functional effect\": 0.0315, \"times_seen\": 19.0}, {\"site\": 150, \"mutant\": \"N\", \"log2 fold change IC90\": -0.14298190614175288, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.07919320331131861, \"functional effect\": 0.1457, \"times_seen\": 39.0}, {\"site\": 150, \"mutant\": \"P\", \"log2 fold change IC90\": -0.007809224853371114, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08697189680887797, \"functional effect\": -0.4192, \"times_seen\": 7.0}, {\"site\": 150, \"mutant\": \"R\", \"log2 fold change IC90\": 0.01721108849379805, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08849338477709827, \"functional effect\": -0.025, \"times_seen\": 24.0}, {\"site\": 150, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 150, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02681398563246447, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08583372074282662, \"functional effect\": 0.2218, \"times_seen\": 8.0}, {\"site\": 150, \"mutant\": \"V\", \"log2 fold change IC90\": -0.28221464751767644, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.07190758092507216, \"functional effect\": -0.1881, \"times_seen\": 11.0}, {\"site\": 150, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018950409654121193, \"epitope\": \"all\", \"reference_site\": \"155\", \"IC90\": 0.08630284469883483, \"functional effect\": -0.183, \"times_seen\": 10.0}, {\"site\": 151, \"mutant\": \"*\", \"log2 fold change IC90\": -0.008548390653760654, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08692734811074593, \"functional effect\": -2.2596, \"times_seen\": 1.0}, {\"site\": 151, \"mutant\": \"-\", \"log2 fold change IC90\": 0.04556078572399625, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.0902495231591183, \"functional effect\": -0.348, \"times_seen\": 25.0}, {\"site\": 151, \"mutant\": \"A\", \"log2 fold change IC90\": 0.014040027017521333, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08829908883763148, \"functional effect\": -0.2672, \"times_seen\": 13.0}, {\"site\": 151, \"mutant\": \"D\", \"log2 fold change IC90\": 0.39542246745682275, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.1150174610347929, \"functional effect\": -0.0483, \"times_seen\": 64.0}, {\"site\": 151, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 151, \"mutant\": \"G\", \"log2 fold change IC90\": 0.02379673080148955, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08889826449483712, \"functional effect\": -0.1704, \"times_seen\": 25.0}, {\"site\": 151, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0316412391241675, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.08554700130676089, \"functional effect\": -0.011, \"times_seen\": 27.0}, {\"site\": 151, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03271089519712664, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.0894492520490285, \"functional effect\": -0.0518, \"times_seen\": 39.0}, {\"site\": 151, \"mutant\": \"V\", \"log2 fold change IC90\": 0.11500962140253006, \"epitope\": \"all\", \"reference_site\": \"156\", \"IC90\": 0.09470024414593682, \"functional effect\": -0.0439, \"times_seen\": 27.0}, {\"site\": 152, \"mutant\": \"*\", \"log2 fold change IC90\": -0.007174259235729559, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08701018370745989, \"functional effect\": -2.1956, \"times_seen\": 3.0}, {\"site\": 152, \"mutant\": \"-\", \"log2 fold change IC90\": -0.09120225887028471, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08208714237518705, \"functional effect\": 0.0351, \"times_seen\": 24.0}, {\"site\": 152, \"mutant\": \"A\", \"log2 fold change IC90\": 0.2063210537808379, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.10088778304458887, \"functional effect\": 0.0147, \"times_seen\": 109.0}, {\"site\": 152, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04036624907896724, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08503119862009412, \"functional effect\": -0.0333, \"times_seen\": 96.0}, {\"site\": 152, \"mutant\": \"D\", \"log2 fold change IC90\": -0.022687886903886744, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.0860795560195378, \"functional effect\": 0.0643, \"times_seen\": 47.0}, {\"site\": 152, \"mutant\": \"E\", \"log2 fold change IC90\": -0.023073933342162036, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08605652533085306, \"functional effect\": -0.1051, \"times_seen\": 6.0}, {\"site\": 152, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 152, \"mutant\": \"G\", \"log2 fold change IC90\": -0.19897778541210923, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.07617833407374884, \"functional effect\": -0.0596, \"times_seen\": 71.0}, {\"site\": 152, \"mutant\": \"H\", \"log2 fold change IC90\": 0.09476272910156604, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.09338049607612427, \"functional effect\": -0.1837, \"times_seen\": 76.0}, {\"site\": 152, \"mutant\": \"I\", \"log2 fold change IC90\": 0.3296054921206607, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.10988815777294896, \"functional effect\": 0.0831, \"times_seen\": 84.0}, {\"site\": 152, \"mutant\": \"K\", \"log2 fold change IC90\": 0.094715034769583, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.09337740904342715, \"functional effect\": -0.1089, \"times_seen\": 26.0}, {\"site\": 152, \"mutant\": \"L\", \"log2 fold change IC90\": 0.1028255663659607, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.09390383576908469, \"functional effect\": -0.0042, \"times_seen\": 226.0}, {\"site\": 152, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06598172313306246, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08353476880943547, \"functional effect\": 0.1247, \"times_seen\": 27.0}, {\"site\": 152, \"mutant\": \"N\", \"log2 fold change IC90\": 0.9414766115578082, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.16793547736681544, \"functional effect\": 0.06, \"times_seen\": 53.0}, {\"site\": 152, \"mutant\": \"P\", \"log2 fold change IC90\": -0.20596284427503098, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.07581039486479081, \"functional effect\": -0.0087, \"times_seen\": 136.0}, {\"site\": 152, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.006181446875039087, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08781941782686044, \"functional effect\": -0.0048, \"times_seen\": 49.0}, {\"site\": 152, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0080419108109129, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.0879327406351772, \"functional effect\": -0.0804, \"times_seen\": 106.0}, {\"site\": 152, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05784205950267763, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08400740275641387, \"functional effect\": 0.0097, \"times_seen\": 255.0}, {\"site\": 152, \"mutant\": \"T\", \"log2 fold change IC90\": -0.6596952861821495, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.055353066290857504, \"functional effect\": 0.0486, \"times_seen\": 93.0}, {\"site\": 152, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1406876722412598, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.07931923983801964, \"functional effect\": 0.01, \"times_seen\": 83.0}, {\"site\": 152, \"mutant\": \"W\", \"log2 fold change IC90\": -0.037321500895328256, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.08521084294538499, \"functional effect\": 0.1925, \"times_seen\": 31.0}, {\"site\": 152, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.34629547244443, \"epitope\": \"all\", \"reference_site\": \"157\", \"IC90\": 0.06878352493499948, \"functional effect\": 0.0065, \"times_seen\": 94.0}, {\"site\": 153, \"mutant\": \"-\", \"log2 fold change IC90\": -0.011379338317609147, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08675694100431958, \"functional effect\": -0.1961, \"times_seen\": 29.0}, {\"site\": 153, \"mutant\": \"G\", \"log2 fold change IC90\": -0.6085844851837597, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.057349226919287385, \"functional effect\": 0.075, \"times_seen\": 54.0}, {\"site\": 153, \"mutant\": \"I\", \"log2 fold change IC90\": -0.07782094401389973, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08285206064353101, \"functional effect\": 0.1199, \"times_seen\": 64.0}, {\"site\": 153, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0032712148765744096, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08724589838872308, \"functional effect\": 0.0516, \"times_seen\": 28.0}, {\"site\": 153, \"mutant\": \"M\", \"log2 fold change IC90\": 0.015322201254819479, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.08837759825063458, \"functional effect\": 0.0289, \"times_seen\": 19.0}, {\"site\": 153, \"mutant\": \"N\", \"log2 fold change IC90\": 1.0384838431246517, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.17961580109945735, \"functional effect\": 0.1885, \"times_seen\": 23.0}, {\"site\": 153, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 153, \"mutant\": \"S\", \"log2 fold change IC90\": 0.4625987733004923, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.1204996705519909, \"functional effect\": 0.086, \"times_seen\": 65.0}, {\"site\": 153, \"mutant\": \"T\", \"log2 fold change IC90\": 0.21080415533213276, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": 0.10120177430863198, \"functional effect\": 0.044, \"times_seen\": 18.0}, {\"site\": 153, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"158\", \"IC90\": null, \"functional effect\": 0.27, \"times_seen\": null}, {\"site\": 154, \"mutant\": \"-\", \"log2 fold change IC90\": 0.013214906809073633, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08824860240089462, \"functional effect\": 0.128, \"times_seen\": 20.0}, {\"site\": 154, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04787864722318053, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08458957517546772, \"functional effect\": -0.1293, \"times_seen\": 32.0}, {\"site\": 154, \"mutant\": \"F\", \"log2 fold change IC90\": -0.141202767726702, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.07929092499092263, \"functional effect\": -0.0272, \"times_seen\": 44.0}, {\"site\": 154, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": null, \"functional effect\": -0.0379, \"times_seen\": null}, {\"site\": 154, \"mutant\": \"I\", \"log2 fold change IC90\": 1.0405514845768538, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.17987340739906219, \"functional effect\": -0.0127, \"times_seen\": 41.0}, {\"site\": 154, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01686824125806988, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08847235738963406, \"functional effect\": 0.1168, \"times_seen\": 16.0}, {\"site\": 154, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 154, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.021183757561985674, \"epitope\": \"all\", \"reference_site\": \"159\", \"IC90\": 0.08873739989857701, \"functional effect\": -0.0122, \"times_seen\": 1.0}, {\"site\": 155, \"mutant\": \"*\", \"log2 fold change IC90\": -0.004083081011280358, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08719681520625465, \"functional effect\": -2.7036, \"times_seen\": 1.0}, {\"site\": 155, \"mutant\": \"-\", \"log2 fold change IC90\": -0.052315205728862224, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08432984589018164, \"functional effect\": 0.2207, \"times_seen\": 21.0}, {\"site\": 155, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04482634669175202, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08476873024225413, \"functional effect\": -0.3634, \"times_seen\": 24.0}, {\"site\": 155, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 155, \"mutant\": \"F\", \"log2 fold change IC90\": -0.08418505985793578, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08248738285789625, \"functional effect\": 0.0013, \"times_seen\": 18.0}, {\"site\": 155, \"mutant\": \"H\", \"log2 fold change IC90\": -0.013218239707699253, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08664642851032837, \"functional effect\": -0.025, \"times_seen\": 66.0}, {\"site\": 155, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004648901444270294, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.0871626235964208, \"functional effect\": 0.1281, \"times_seen\": 22.0}, {\"site\": 155, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01316282182541142, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08824541645797973, \"functional effect\": -0.5272, \"times_seen\": 3.0}, {\"site\": 155, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 155, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03409809795368207, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.08953530205983262, \"functional effect\": -0.4175, \"times_seen\": 8.0}, {\"site\": 155, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"160\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 156, \"mutant\": \"-\", \"log2 fold change IC90\": 0.02600958472547938, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08903472425383199, \"functional effect\": -0.0075, \"times_seen\": 19.0}, {\"site\": 156, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04733500909023436, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.0846214563303709, \"functional effect\": 0.1208, \"times_seen\": 13.0}, {\"site\": 156, \"mutant\": \"F\", \"log2 fold change IC90\": -0.09398077607805741, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.0819292011336161, \"functional effect\": -0.0904, \"times_seen\": 94.0}, {\"site\": 156, \"mutant\": \"P\", \"log2 fold change IC90\": -0.06149058196461916, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08379521955309804, \"functional effect\": -0.1525, \"times_seen\": 24.0}, {\"site\": 156, \"mutant\": \"R\", \"log2 fold change IC90\": -0.016423505762677208, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08645413799640377, \"functional effect\": 0.0846, \"times_seen\": 10.0}, {\"site\": 156, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 156, \"mutant\": \"T\", \"log2 fold change IC90\": -0.020605945386160694, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.08620386640307164, \"functional effect\": -0.1456, \"times_seen\": 32.0}, {\"site\": 156, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.1890241927837566, \"epitope\": \"all\", \"reference_site\": \"161\", \"IC90\": 0.07670572884612349, \"functional effect\": 0.066, \"times_seen\": 26.0}, {\"site\": 157, \"mutant\": \"-\", \"log2 fold change IC90\": 0.3233485221228116, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.109412604692929, \"functional effect\": 0.1466, \"times_seen\": 26.0}, {\"site\": 157, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": null, \"functional effect\": -2.4732, \"times_seen\": null}, {\"site\": 157, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 157, \"mutant\": \"F\", \"log2 fold change IC90\": -0.015580690322700843, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08650465883974762, \"functional effect\": -0.1564, \"times_seen\": 9.0}, {\"site\": 157, \"mutant\": \"G\", \"log2 fold change IC90\": 0.06799004943635177, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.09166357622745355, \"functional effect\": -0.1405, \"times_seen\": 15.0}, {\"site\": 157, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04534501814340876, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.084738260034319, \"functional effect\": -0.0007, \"times_seen\": 89.0}, {\"site\": 157, \"mutant\": \"L\", \"log2 fold change IC90\": 0.2969764795377248, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.10743074344831877, \"functional effect\": -0.2646, \"times_seen\": 18.0}, {\"site\": 157, \"mutant\": \"N\", \"log2 fold change IC90\": -0.3523448841963226, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.06849571033149982, \"functional effect\": -0.0073, \"times_seen\": 65.0}, {\"site\": 157, \"mutant\": \"P\", \"log2 fold change IC90\": -0.04056275267006595, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08501961765701148, \"functional effect\": -0.2622, \"times_seen\": 12.0}, {\"site\": 157, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0649522365391871, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.09147076775070315, \"functional effect\": -0.008, \"times_seen\": 11.0}, {\"site\": 157, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 157, \"mutant\": \"T\", \"log2 fold change IC90\": 0.013502886958473506, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08826621969465002, \"functional effect\": -0.0481, \"times_seen\": 19.0}, {\"site\": 157, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008705082140443373, \"epitope\": \"all\", \"reference_site\": \"162\", \"IC90\": 0.08691790742136139, \"functional effect\": 0.0921, \"times_seen\": 5.0}, {\"site\": 158, \"mutant\": \"-\", \"log2 fold change IC90\": 0.0045534278960383725, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08772037330493926, \"functional effect\": 0.0687, \"times_seen\": 20.0}, {\"site\": 158, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 158, \"mutant\": \"D\", \"log2 fold change IC90\": -0.003527583056956114, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.087230396093106, \"functional effect\": 0.033, \"times_seen\": 3.0}, {\"site\": 158, \"mutant\": \"E\", \"log2 fold change IC90\": -0.008936468790164428, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08690396821029304, \"functional effect\": 0.2321, \"times_seen\": 17.0}, {\"site\": 158, \"mutant\": \"G\", \"log2 fold change IC90\": 0.030050975751186787, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08928448500031914, \"functional effect\": 0.047, \"times_seen\": 27.0}, {\"site\": 158, \"mutant\": \"I\", \"log2 fold change IC90\": 0.319091697895016, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.10909024704562718, \"functional effect\": -0.0315, \"times_seen\": 18.0}, {\"site\": 158, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08149386878712668, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0826413977253429, \"functional effect\": 0.099, \"times_seen\": 12.0}, {\"site\": 158, \"mutant\": \"P\", \"log2 fold change IC90\": -0.003041992740672887, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08725976152641844, \"functional effect\": 0.2722, \"times_seen\": 1.0}, {\"site\": 158, \"mutant\": \"R\", \"log2 fold change IC90\": 0.008158907880206333, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08793987193446262, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 158, \"mutant\": \"S\", \"log2 fold change IC90\": 0.1432659672735604, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0965733076546534, \"functional effect\": 0.0681, \"times_seen\": 116.0}, {\"site\": 158, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05916445316986899, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.08393043572171764, \"functional effect\": 0.0047, \"times_seen\": 96.0}, {\"site\": 158, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05030129712469528, \"epitope\": \"all\", \"reference_site\": \"163\", \"IC90\": 0.0844476470818601, \"functional effect\": 0.0087, \"times_seen\": 82.0}, {\"site\": 159, \"mutant\": \"-\", \"log2 fold change IC90\": 0.020458936429856772, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08869282874083187, \"functional effect\": -0.1313, \"times_seen\": 35.0}, {\"site\": 159, \"mutant\": \"D\", \"log2 fold change IC90\": -0.005532159554060044, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08710927654110613, \"functional effect\": -0.0898, \"times_seen\": 17.0}, {\"site\": 159, \"mutant\": \"H\", \"log2 fold change IC90\": 0.20615900171155746, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.10087645136646839, \"functional effect\": 0.014, \"times_seen\": 51.0}, {\"site\": 159, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011260240328009725, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08676410329674175, \"functional effect\": -0.2323, \"times_seen\": 16.0}, {\"site\": 159, \"mutant\": \"K\", \"log2 fold change IC90\": 0.11552946936415906, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.09473437374232228, \"functional effect\": -0.1011, \"times_seen\": 19.0}, {\"site\": 159, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 159, \"mutant\": \"S\", \"log2 fold change IC90\": -0.09339503893619566, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08196247131052561, \"functional effect\": -0.1513, \"times_seen\": 28.0}, {\"site\": 159, \"mutant\": \"T\", \"log2 fold change IC90\": -0.062046292512560365, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.0837629487551358, \"functional effect\": -0.1756, \"times_seen\": 70.0}, {\"site\": 159, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04163494013886669, \"epitope\": \"all\", \"reference_site\": \"164\", \"IC90\": 0.08495645593448964, \"functional effect\": -0.1064, \"times_seen\": 22.0}, {\"site\": 160, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03412410240801781, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08539990241408141, \"functional effect\": -0.6996, \"times_seen\": 14.0}, {\"site\": 160, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0021252738129777108, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08731522584330577, \"functional effect\": 0.1748, \"times_seen\": 1.0}, {\"site\": 160, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04280293899898787, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08488770343722359, \"functional effect\": -0.3027, \"times_seen\": 16.0}, {\"site\": 160, \"mutant\": \"K\", \"log2 fold change IC90\": 0.002018265265110342, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08756636283972427, \"functional effect\": -0.591, \"times_seen\": 5.0}, {\"site\": 160, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0693970329069363, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08333724980720199, \"functional effect\": -0.311, \"times_seen\": 12.0}, {\"site\": 160, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 160, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": null, \"functional effect\": -0.8719, \"times_seen\": null}, {\"site\": 160, \"mutant\": \"S\", \"log2 fold change IC90\": -0.048385362106437145, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.08455987016569828, \"functional effect\": 0.0485, \"times_seen\": 23.0}, {\"site\": 160, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06405520754590913, \"epitope\": \"all\", \"reference_site\": \"165\", \"IC90\": 0.0836463922141058, \"functional effect\": -0.5794, \"times_seen\": 10.0}, {\"site\": 161, \"mutant\": \"-\", \"log2 fold change IC90\": 0.02605367219705444, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08903744511703673, \"functional effect\": -2.8512, \"times_seen\": 3.0}, {\"site\": 161, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004941187404243189, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.0871449664825892, \"functional effect\": -2.1822, \"times_seen\": 1.0}, {\"site\": 161, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"F\", \"log2 fold change IC90\": -0.003955563778622558, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08720452271731521, \"functional effect\": -2.5685, \"times_seen\": 1.0}, {\"site\": 161, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": null, \"functional effect\": -3.0134, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0030758430750394187, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08763057751536203, \"functional effect\": -2.8823, \"times_seen\": 2.0}, {\"site\": 161, \"mutant\": \"S\", \"log2 fold change IC90\": -0.017586752888292072, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.08638445799356537, \"functional effect\": -2.9128, \"times_seen\": 6.0}, {\"site\": 161, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": null, \"functional effect\": -3.0054, \"times_seen\": null}, {\"site\": 161, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010616920089743652, \"epitope\": \"all\", \"reference_site\": \"166\", \"IC90\": 0.0868028013921343, \"functional effect\": -2.5698, \"times_seen\": 5.0}, {\"site\": 162, \"mutant\": \"-\", \"log2 fold change IC90\": -0.03329182376554814, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08544918311339636, \"functional effect\": -1.1296, \"times_seen\": 11.0}, {\"site\": 162, \"mutant\": \"A\", \"log2 fold change IC90\": -0.10404793921095495, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08135948711040768, \"functional effect\": -0.2336, \"times_seen\": 8.0}, {\"site\": 162, \"mutant\": \"E\", \"log2 fold change IC90\": -0.02038056790064403, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08621733420307856, \"functional effect\": -0.4323, \"times_seen\": 7.0}, {\"site\": 162, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02016192427922031, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.0862304016207677, \"functional effect\": -0.6835, \"times_seen\": 45.0}, {\"site\": 162, \"mutant\": \"L\", \"log2 fold change IC90\": 0.037420906316424744, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.08974175700383857, \"functional effect\": -0.708, \"times_seen\": 11.0}, {\"site\": 162, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": null, \"functional effect\": -0.1392, \"times_seen\": null}, {\"site\": 162, \"mutant\": \"S\", \"log2 fold change IC90\": -1.1380321043569357, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.039732688585368034, \"functional effect\": 0.0177, \"times_seen\": 71.0}, {\"site\": 162, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 162, \"mutant\": \"V\", \"log2 fold change IC90\": -0.2904857692769513, \"epitope\": \"all\", \"reference_site\": \"167\", \"IC90\": 0.07149650672459631, \"functional effect\": -0.0554, \"times_seen\": 11.0}, {\"site\": 163, \"mutant\": \"-\", \"log2 fold change IC90\": 0.07983677169322467, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.09241937258464573, \"functional effect\": -0.4392, \"times_seen\": 23.0}, {\"site\": 163, \"mutant\": \"A\", \"log2 fold change IC90\": 0.6977208671429943, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.1418288764337661, \"functional effect\": -0.4464, \"times_seen\": 19.0}, {\"site\": 163, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": null, \"functional effect\": -0.2547, \"times_seen\": null}, {\"site\": 163, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 163, \"mutant\": \"I\", \"log2 fold change IC90\": 0.007907546451782672, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.08792455146433216, \"functional effect\": -0.3046, \"times_seen\": 5.0}, {\"site\": 163, \"mutant\": \"L\", \"log2 fold change IC90\": -0.3275160415342655, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.06968472656536072, \"functional effect\": -0.0966, \"times_seen\": 62.0}, {\"site\": 163, \"mutant\": \"S\", \"log2 fold change IC90\": 0.10363563047881508, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.09395657698267626, \"functional effect\": -0.5267, \"times_seen\": 9.0}, {\"site\": 163, \"mutant\": \"V\", \"log2 fold change IC90\": 0.021143179397880265, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": 0.08873490404877189, \"functional effect\": 0.0364, \"times_seen\": 2.0}, {\"site\": 163, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"168\", \"IC90\": null, \"functional effect\": -0.8997, \"times_seen\": null}, {\"site\": 164, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": null, \"functional effect\": -3.0021, \"times_seen\": null}, {\"site\": 164, \"mutant\": \"-\", \"log2 fold change IC90\": 0.02833941917581362, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08917862421077277, \"functional effect\": -1.1936, \"times_seen\": 6.0}, {\"site\": 164, \"mutant\": \"D\", \"log2 fold change IC90\": -0.060402395087137954, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08385844792329729, \"functional effect\": 0.0394, \"times_seen\": 29.0}, {\"site\": 164, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 164, \"mutant\": \"G\", \"log2 fold change IC90\": 0.01734935223812596, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08850186613504539, \"functional effect\": -0.515, \"times_seen\": 3.0}, {\"site\": 164, \"mutant\": \"K\", \"log2 fold change IC90\": -0.18678166189234355, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.07682505325029501, \"functional effect\": -0.4174, \"times_seen\": 92.0}, {\"site\": 164, \"mutant\": \"N\", \"log2 fold change IC90\": -0.047687081272632076, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08460080801248901, \"functional effect\": 0.0342, \"times_seen\": 19.0}, {\"site\": 164, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05893794165955221, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08394361432269107, \"functional effect\": -0.3936, \"times_seen\": 11.0}, {\"site\": 164, \"mutant\": \"V\", \"log2 fold change IC90\": 0.013941933587376783, \"epitope\": \"all\", \"reference_site\": \"169\", \"IC90\": 0.08829308530549172, \"functional effect\": -0.3211, \"times_seen\": 15.0}, {\"site\": 165, \"mutant\": \"*\", \"log2 fold change IC90\": 0.004341868765949506, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08770751079088249, \"functional effect\": -1.4378, \"times_seen\": 1.0}, {\"site\": 165, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0033440089075411545, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08724149633546437, \"functional effect\": -0.3881, \"times_seen\": 16.0}, {\"site\": 165, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02512719762344732, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08593413556339999, \"functional effect\": -0.7147, \"times_seen\": 14.0}, {\"site\": 165, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": null, \"functional effect\": -0.3584, \"times_seen\": null}, {\"site\": 165, \"mutant\": \"F\", \"log2 fold change IC90\": -0.017244340678868313, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08640496309183086, \"functional effect\": -0.0061, \"times_seen\": 20.0}, {\"site\": 165, \"mutant\": \"H\", \"log2 fold change IC90\": 0.17910950752242838, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.09900271100272068, \"functional effect\": -0.059, \"times_seen\": 60.0}, {\"site\": 165, \"mutant\": \"I\", \"log2 fold change IC90\": -0.006964174383291927, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08702285502889698, \"functional effect\": -0.2233, \"times_seen\": 7.0}, {\"site\": 165, \"mutant\": \"M\", \"log2 fold change IC90\": 0.01639044476033817, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08844306167416577, \"functional effect\": -0.1524, \"times_seen\": 7.0}, {\"site\": 165, \"mutant\": \"N\", \"log2 fold change IC90\": 0.03417973598443432, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.08954036875262025, \"functional effect\": -0.7647, \"times_seen\": 4.0}, {\"site\": 165, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"170\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 166, \"mutant\": \"-\", \"log2 fold change IC90\": -0.06443816845053711, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08362419137060957, \"functional effect\": -0.2477, \"times_seen\": 18.0}, {\"site\": 166, \"mutant\": \"A\", \"log2 fold change IC90\": 0.03759524641612432, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08975260235354203, \"functional effect\": -0.1624, \"times_seen\": 47.0}, {\"site\": 166, \"mutant\": \"C\", \"log2 fold change IC90\": -0.011801357718457648, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08673156644026803, \"functional effect\": -0.6295, \"times_seen\": 13.0}, {\"site\": 166, \"mutant\": \"E\", \"log2 fold change IC90\": -0.017828652938037162, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08636997492381254, \"functional effect\": 0.0418, \"times_seen\": 4.0}, {\"site\": 166, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009796170932583483, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08685219755214615, \"functional effect\": 0.0087, \"times_seen\": 34.0}, {\"site\": 166, \"mutant\": \"I\", \"log2 fold change IC90\": 0.048965295570908486, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.09046274785428125, \"functional effect\": 0.0754, \"times_seen\": 48.0}, {\"site\": 166, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0420861131304097, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.09003242238080868, \"functional effect\": -0.14, \"times_seen\": 37.0}, {\"site\": 166, \"mutant\": \"M\", \"log2 fold change IC90\": -0.008536377857639192, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.0869280719261249, \"functional effect\": -0.0036, \"times_seen\": 14.0}, {\"site\": 166, \"mutant\": \"S\", \"log2 fold change IC90\": -0.012505702231458476, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.08668923317413746, \"functional effect\": -0.1799, \"times_seen\": 5.0}, {\"site\": 166, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"171\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 167, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03698516040572808, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08523071076004335, \"functional effect\": -0.0799, \"times_seen\": 6.0}, {\"site\": 167, \"mutant\": \"C\", \"log2 fold change IC90\": -0.004850932612164538, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08715041842956153, \"functional effect\": -1.1398, \"times_seen\": 1.0}, {\"site\": 167, \"mutant\": \"F\", \"log2 fold change IC90\": -0.016651362864146046, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08644048463710939, \"functional effect\": -0.1085, \"times_seen\": 28.0}, {\"site\": 167, \"mutant\": \"G\", \"log2 fold change IC90\": -0.005201100728423098, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08712926801749382, \"functional effect\": -0.1978, \"times_seen\": 7.0}, {\"site\": 167, \"mutant\": \"I\", \"log2 fold change IC90\": -0.006934269489122885, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08702465890024079, \"functional effect\": -0.5557, \"times_seen\": 3.0}, {\"site\": 167, \"mutant\": \"L\", \"log2 fold change IC90\": -0.16741550110428083, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.07786327476081265, \"functional effect\": -0.1065, \"times_seen\": 6.0}, {\"site\": 167, \"mutant\": \"N\", \"log2 fold change IC90\": -0.06486158447368308, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.083599652139421, \"functional effect\": -0.0688, \"times_seen\": 32.0}, {\"site\": 167, \"mutant\": \"R\", \"log2 fold change IC90\": -0.014213337386958852, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08658668481629667, \"functional effect\": -0.2875, \"times_seen\": 3.0}, {\"site\": 167, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 167, \"mutant\": \"T\", \"log2 fold change IC90\": -0.028069758662278132, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08575904052905857, \"functional effect\": -0.0488, \"times_seen\": 23.0}, {\"site\": 167, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.011951929280100963, \"epitope\": \"all\", \"reference_site\": \"172\", \"IC90\": 0.08817138079345466, \"functional effect\": -0.3347, \"times_seen\": 14.0}, {\"site\": 168, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": null, \"functional effect\": -1.0772, \"times_seen\": null}, {\"site\": 168, \"mutant\": \"D\", \"log2 fold change IC90\": -0.015102889304399878, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08653331275340677, \"functional effect\": -0.1765, \"times_seen\": 3.0}, {\"site\": 168, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": null, \"functional effect\": 0.06, \"times_seen\": null}, {\"site\": 168, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0038140433121925717, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08767542792667571, \"functional effect\": 0.0195, \"times_seen\": 29.0}, {\"site\": 168, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0012598760834434592, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08736761741849321, \"functional effect\": -0.1131, \"times_seen\": 29.0}, {\"site\": 168, \"mutant\": \"L\", \"log2 fold change IC90\": 0.031334184252845204, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.0893639346238567, \"functional effect\": 0.0819, \"times_seen\": 10.0}, {\"site\": 168, \"mutant\": \"P\", \"log2 fold change IC90\": 0.025049265235888688, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.08897547865582159, \"functional effect\": -0.1616, \"times_seen\": 13.0}, {\"site\": 168, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 168, \"mutant\": \"R\", \"log2 fold change IC90\": -0.7672648708293025, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.05137596733359252, \"functional effect\": 0.0184, \"times_seen\": 19.0}, {\"site\": 168, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008859913703294567, \"epitope\": \"all\", \"reference_site\": \"173\", \"IC90\": 0.0869085797998292, \"functional effect\": 0.1903, \"times_seen\": 11.0}, {\"site\": 169, \"mutant\": \"A\", \"log2 fold change IC90\": 0.3353435469741105, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.11032608807722029, \"functional effect\": -0.0202, \"times_seen\": 16.0}, {\"site\": 169, \"mutant\": \"H\", \"log2 fold change IC90\": -0.10462151552691634, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08132714721995905, \"functional effect\": -0.2334, \"times_seen\": 21.0}, {\"site\": 169, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03006760309273735, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08564036358055005, \"functional effect\": -0.2764, \"times_seen\": 33.0}, {\"site\": 169, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 169, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0007119769400541197, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08748711175476882, \"functional effect\": -0.4791, \"times_seen\": 5.0}, {\"site\": 169, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0175464395741213, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.0885139572478643, \"functional effect\": -0.2852, \"times_seen\": 6.0}, {\"site\": 169, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04120481083375108, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.08498178887615085, \"functional effect\": 0.1185, \"times_seen\": 39.0}, {\"site\": 169, \"mutant\": \"T\", \"log2 fold change IC90\": 0.14055700071389107, \"epitope\": \"all\", \"reference_site\": \"174\", \"IC90\": 0.09639214088729532, \"functional effect\": 0.0123, \"times_seen\": 35.0}, {\"site\": 170, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 170, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 170, \"mutant\": \"H\", \"log2 fold change IC90\": -0.007407479007935528, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08699611915844632, \"functional effect\": 0.2269, \"times_seen\": 1.0}, {\"site\": 170, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0356328443547965, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08531063956757817, \"functional effect\": 0.0932, \"times_seen\": 22.0}, {\"site\": 170, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0395574828485801, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08507887996629232, \"functional effect\": -0.0807, \"times_seen\": 30.0}, {\"site\": 170, \"mutant\": \"S\", \"log2 fold change IC90\": 0.010331034659012799, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08807237424099937, \"functional effect\": -0.1024, \"times_seen\": 26.0}, {\"site\": 170, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02258886748744705, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08608546429514458, \"functional effect\": 0.1541, \"times_seen\": 5.0}, {\"site\": 170, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.016014388780708856, \"epitope\": \"all\", \"reference_site\": \"175\", \"IC90\": 0.08647865798888225, \"functional effect\": -0.6476, \"times_seen\": 3.0}, {\"site\": 171, \"mutant\": \"*\", \"log2 fold change IC90\": -0.02408258796205909, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08599638027381838, \"functional effect\": -2.6513, \"times_seen\": 6.0}, {\"site\": 171, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": null, \"functional effect\": -0.5502, \"times_seen\": null}, {\"site\": 171, \"mutant\": \"A\", \"log2 fold change IC90\": 0.3561802044591081, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.11193107588369483, \"functional effect\": -0.075, \"times_seen\": 88.0}, {\"site\": 171, \"mutant\": \"C\", \"log2 fold change IC90\": -1.2823483134301883, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.03595045949275228, \"functional effect\": -0.175, \"times_seen\": 42.0}, {\"site\": 171, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0429384278990526, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08487973168907749, \"functional effect\": -0.2332, \"times_seen\": 24.0}, {\"site\": 171, \"mutant\": \"E\", \"log2 fold change IC90\": -0.017943450715768076, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08636310258667047, \"functional effect\": -0.0566, \"times_seen\": 40.0}, {\"site\": 171, \"mutant\": \"F\", \"log2 fold change IC90\": 0.8455327345408169, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.15713049123486328, \"functional effect\": 0.0043, \"times_seen\": 75.0}, {\"site\": 171, \"mutant\": \"G\", \"log2 fold change IC90\": -0.13104103059656197, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.07985138843733723, \"functional effect\": -0.0638, \"times_seen\": 64.0}, {\"site\": 171, \"mutant\": \"H\", \"log2 fold change IC90\": 0.11646025234437958, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.09479551320072849, \"functional effect\": -0.0169, \"times_seen\": 66.0}, {\"site\": 171, \"mutant\": \"I\", \"log2 fold change IC90\": -0.16374338593589177, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.07806171385933662, \"functional effect\": 0.0243, \"times_seen\": 48.0}, {\"site\": 171, \"mutant\": \"K\", \"log2 fold change IC90\": 0.5685733276403103, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.1296842931330275, \"functional effect\": -0.3255, \"times_seen\": 60.0}, {\"site\": 171, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 171, \"mutant\": \"M\", \"log2 fold change IC90\": -1.3720441317561762, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.03378339676884307, \"functional effect\": 0.0666, \"times_seen\": 68.0}, {\"site\": 171, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0006732756266968565, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08748476488268771, \"functional effect\": -0.0796, \"times_seen\": 29.0}, {\"site\": 171, \"mutant\": \"P\", \"log2 fold change IC90\": -0.06669895727411856, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08349324991885841, \"functional effect\": -0.1479, \"times_seen\": 181.0}, {\"site\": 171, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.019483554179673793, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08863288525227758, \"functional effect\": -0.1346, \"times_seen\": 95.0}, {\"site\": 171, \"mutant\": \"R\", \"log2 fold change IC90\": 0.05018493651554703, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.09053925655370601, \"functional effect\": -0.2682, \"times_seen\": 142.0}, {\"site\": 171, \"mutant\": \"S\", \"log2 fold change IC90\": 0.2274190875759318, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.10237401112988555, \"functional effect\": -0.0793, \"times_seen\": 132.0}, {\"site\": 171, \"mutant\": \"T\", \"log2 fold change IC90\": -0.7564402447775381, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.05176289400075223, \"functional effect\": -0.0044, \"times_seen\": 94.0}, {\"site\": 171, \"mutant\": \"V\", \"log2 fold change IC90\": 0.019263050693440302, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08861933951588834, \"functional effect\": -0.0387, \"times_seen\": 106.0}, {\"site\": 171, \"mutant\": \"W\", \"log2 fold change IC90\": -0.11572721003390037, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08070350397725594, \"functional effect\": 0.0425, \"times_seen\": 31.0}, {\"site\": 171, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027974015156513127, \"epitope\": \"all\", \"reference_site\": \"176\", \"IC90\": 0.08576473206013002, \"functional effect\": -0.0488, \"times_seen\": 34.0}, {\"site\": 172, \"mutant\": \"I\", \"log2 fold change IC90\": 0.4436279304670208, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.11892552212677683, \"functional effect\": 0.0731, \"times_seen\": 130.0}, {\"site\": 172, \"mutant\": \"K\", \"log2 fold change IC90\": 0.24278281311950134, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.10347005072723614, \"functional effect\": 0.0748, \"times_seen\": 121.0}, {\"site\": 172, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04293264518396752, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08488007191086702, \"functional effect\": -0.0551, \"times_seen\": 39.0}, {\"site\": 172, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 172, \"mutant\": \"N\", \"log2 fold change IC90\": 0.019225762086346604, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08861704904636146, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 172, \"mutant\": \"R\", \"log2 fold change IC90\": -0.042903886686508276, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.0848817639161716, \"functional effect\": 0.0645, \"times_seen\": 12.0}, {\"site\": 172, \"mutant\": \"T\", \"log2 fold change IC90\": 0.09404715971829579, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.09333419131067659, \"functional effect\": -0.0037, \"times_seen\": 38.0}, {\"site\": 172, \"mutant\": \"V\", \"log2 fold change IC90\": -0.11901141563571443, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08051999641693565, \"functional effect\": -0.0063, \"times_seen\": 46.0}, {\"site\": 172, \"mutant\": \"W\", \"log2 fold change IC90\": 0.003298484961528678, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.08764410202474313, \"functional effect\": 0.1881, \"times_seen\": 13.0}, {\"site\": 172, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04170910113015718, \"epitope\": \"all\", \"reference_site\": \"177\", \"IC90\": 0.09000889774950395, \"functional effect\": 0.1976, \"times_seen\": 19.0}, {\"site\": 173, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": null, \"functional effect\": -2.3457, \"times_seen\": null}, {\"site\": 173, \"mutant\": \"A\", \"log2 fold change IC90\": -0.010605341285476496, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08680349805820159, \"functional effect\": -0.0751, \"times_seen\": 100.0}, {\"site\": 173, \"mutant\": \"C\", \"log2 fold change IC90\": -0.025056716321125314, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08593833388499059, \"functional effect\": -0.359, \"times_seen\": 40.0}, {\"site\": 173, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 173, \"mutant\": \"E\", \"log2 fold change IC90\": 0.030455333269533168, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08930951309819957, \"functional effect\": -0.0638, \"times_seen\": 47.0}, {\"site\": 173, \"mutant\": \"F\", \"log2 fold change IC90\": -0.10492982911938958, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08130976892091728, \"functional effect\": -0.2507, \"times_seen\": 48.0}, {\"site\": 173, \"mutant\": \"G\", \"log2 fold change IC90\": -0.22199330102707857, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.07497269291451998, \"functional effect\": -0.0331, \"times_seen\": 128.0}, {\"site\": 173, \"mutant\": \"H\", \"log2 fold change IC90\": 0.4237484857646471, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.1172980406359628, \"functional effect\": -0.0807, \"times_seen\": 106.0}, {\"site\": 173, \"mutant\": \"I\", \"log2 fold change IC90\": 0.44933694955234543, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.11939706544912877, \"functional effect\": -0.2644, \"times_seen\": 32.0}, {\"site\": 173, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01021726828810982, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.0868268506197372, \"functional effect\": 0.1292, \"times_seen\": 27.0}, {\"site\": 173, \"mutant\": \"L\", \"log2 fold change IC90\": 0.9410145008598901, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.16788169444599219, \"functional effect\": -0.2273, \"times_seen\": 61.0}, {\"site\": 173, \"mutant\": \"M\", \"log2 fold change IC90\": -0.023267094002630086, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08604500410006603, \"functional effect\": -0.4233, \"times_seen\": 20.0}, {\"site\": 173, \"mutant\": \"N\", \"log2 fold change IC90\": -0.379211600365587, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.06723194669736549, \"functional effect\": -0.0223, \"times_seen\": 168.0}, {\"site\": 173, \"mutant\": \"P\", \"log2 fold change IC90\": -0.06785001895226622, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08342666096654965, \"functional effect\": -0.1434, \"times_seen\": 44.0}, {\"site\": 173, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0796990463238039, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.09241055028725553, \"functional effect\": -0.0238, \"times_seen\": 20.0}, {\"site\": 173, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0025581707542404416, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08728902985402409, \"functional effect\": -0.1216, \"times_seen\": 68.0}, {\"site\": 173, \"mutant\": \"S\", \"log2 fold change IC90\": -1.014944679865591, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.043271401363394586, \"functional effect\": -0.0435, \"times_seen\": 115.0}, {\"site\": 173, \"mutant\": \"T\", \"log2 fold change IC90\": -0.1399957447836488, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.07935729106970658, \"functional effect\": -0.0833, \"times_seen\": 105.0}, {\"site\": 173, \"mutant\": \"V\", \"log2 fold change IC90\": -0.10894178469606472, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08108397066459161, \"functional effect\": -0.2056, \"times_seen\": 80.0}, {\"site\": 173, \"mutant\": \"W\", \"log2 fold change IC90\": -0.03520040112922092, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.08533621499189724, \"functional effect\": -0.3205, \"times_seen\": 13.0}, {\"site\": 173, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.17044304889542503, \"epitope\": \"all\", \"reference_site\": \"178\", \"IC90\": 0.07770004718826287, \"functional effect\": -0.2031, \"times_seen\": 137.0}, {\"site\": 174, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": null, \"functional effect\": -3.2847, \"times_seen\": null}, {\"site\": 174, \"mutant\": \"F\", \"log2 fold change IC90\": -0.10299665819746191, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.0814187947619623, \"functional effect\": 0.1159, \"times_seen\": 80.0}, {\"site\": 174, \"mutant\": \"I\", \"log2 fold change IC90\": 0.09570914705322325, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.09344177442644118, \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 174, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 174, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0036342958285638296, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.08766450499743955, \"functional effect\": -0.1622, \"times_seen\": 3.0}, {\"site\": 174, \"mutant\": \"P\", \"log2 fold change IC90\": 0.003370327893952566, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.08764846661039823, \"functional effect\": 0.2061, \"times_seen\": 27.0}, {\"site\": 174, \"mutant\": \"R\", \"log2 fold change IC90\": -0.24333415146796986, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.07387183280467731, \"functional effect\": -0.1583, \"times_seen\": 13.0}, {\"site\": 174, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07033056653287101, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.0832833416994215, \"functional effect\": 0.0705, \"times_seen\": 32.0}, {\"site\": 174, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": null, \"functional effect\": 0.3709, \"times_seen\": null}, {\"site\": 174, \"mutant\": \"W\", \"log2 fold change IC90\": 0.02502378021262321, \"epitope\": \"all\", \"reference_site\": \"179\", \"IC90\": 0.08897390692926017, \"functional effect\": -0.2258, \"times_seen\": 1.0}, {\"site\": 175, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": null, \"functional effect\": -2.3131, \"times_seen\": null}, {\"site\": 175, \"mutant\": \"A\", \"log2 fold change IC90\": -0.5277440433422733, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.06065449144343779, \"functional effect\": -0.1565, \"times_seen\": 22.0}, {\"site\": 175, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010107455311597477, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08683345983202499, \"functional effect\": -0.0057, \"times_seen\": 60.0}, {\"site\": 175, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 175, \"mutant\": \"G\", \"log2 fold change IC90\": -0.06882899851540923, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08337006876282317, \"functional effect\": -0.0243, \"times_seen\": 83.0}, {\"site\": 175, \"mutant\": \"K\", \"log2 fold change IC90\": 0.04273064430745648, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.09007265379892597, \"functional effect\": 0.0545, \"times_seen\": 62.0}, {\"site\": 175, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005261086439151836, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08712564535139716, \"functional effect\": -0.2727, \"times_seen\": 8.0}, {\"site\": 175, \"mutant\": \"R\", \"log2 fold change IC90\": -1.9945281482562667, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.021944058531930075, \"functional effect\": 0.0304, \"times_seen\": 13.0}, {\"site\": 175, \"mutant\": \"V\", \"log2 fold change IC90\": -0.037741514875737334, \"epitope\": \"all\", \"reference_site\": \"180\", \"IC90\": 0.08518603899510471, \"functional effect\": -0.137, \"times_seen\": 50.0}, {\"site\": 176, \"mutant\": \"-\", \"log2 fold change IC90\": 0.00965027969046678, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.0880308259155178, \"functional effect\": 0.0869, \"times_seen\": 1.0}, {\"site\": 176, \"mutant\": \"A\", \"log2 fold change IC90\": -0.11086377923327823, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.08097602048704261, \"functional effect\": 0.0627, \"times_seen\": 47.0}, {\"site\": 176, \"mutant\": \"C\", \"log2 fold change IC90\": 0.05044728471048589, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.09055572224441774, \"functional effect\": 0.0515, \"times_seen\": 4.0}, {\"site\": 176, \"mutant\": \"D\", \"log2 fold change IC90\": -0.18008990680955117, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.07718222406736812, \"functional effect\": 0.0625, \"times_seen\": 42.0}, {\"site\": 176, \"mutant\": \"E\", \"log2 fold change IC90\": 0.4259656603755544, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.1174784461785748, \"functional effect\": 0.0764, \"times_seen\": 47.0}, {\"site\": 176, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 176, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0033950547206711497, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.08723840958864006, \"functional effect\": -0.2688, \"times_seen\": 14.0}, {\"site\": 176, \"mutant\": \"R\", \"log2 fold change IC90\": -0.17662919142823144, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.07736758987464581, \"functional effect\": -0.0258, \"times_seen\": 36.0}, {\"site\": 176, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02395088801320085, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.08890776410521613, \"functional effect\": 0.0761, \"times_seen\": 22.0}, {\"site\": 176, \"mutant\": \"V\", \"log2 fold change IC90\": 0.12956668902430368, \"epitope\": \"all\", \"reference_site\": \"181\", \"IC90\": 0.09566062470148176, \"functional effect\": 0.016, \"times_seen\": 37.0}, {\"site\": 177, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": null, \"functional effect\": -3.2884, \"times_seen\": null}, {\"site\": 177, \"mutant\": \"-\", \"log2 fold change IC90\": 0.007085120237790592, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.08787444326625608, \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 177, \"mutant\": \"E\", \"log2 fold change IC90\": -0.027289272152003042, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.08580544803789024, \"functional effect\": 0.0575, \"times_seen\": 104.0}, {\"site\": 177, \"mutant\": \"I\", \"log2 fold change IC90\": 0.13103784488392484, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.095758222227611, \"functional effect\": 0.0654, \"times_seen\": 15.0}, {\"site\": 177, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 177, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": null, \"functional effect\": -0.3944, \"times_seen\": null}, {\"site\": 177, \"mutant\": \"N\", \"log2 fold change IC90\": -0.09613905701790179, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.08180672616311692, \"functional effect\": 0.0764, \"times_seen\": 131.0}, {\"site\": 177, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02658279836023252, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.08584747642453924, \"functional effect\": -0.0279, \"times_seen\": 17.0}, {\"site\": 177, \"mutant\": \"R\", \"log2 fold change IC90\": -0.5388076355550251, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.06019112944380864, \"functional effect\": 0.0177, \"times_seen\": 116.0}, {\"site\": 177, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02244494340646139, \"epitope\": \"all\", \"reference_site\": \"182\", \"IC90\": 0.08609405265859604, \"functional effect\": 0.2054, \"times_seen\": 22.0}, {\"site\": 178, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006515956318912942, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08704989558442054, \"functional effect\": -2.6882, \"times_seen\": 5.0}, {\"site\": 178, \"mutant\": \"-\", \"log2 fold change IC90\": 0.006157402989020435, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08781795424487154, \"functional effect\": -0.134, \"times_seen\": 1.0}, {\"site\": 178, \"mutant\": \"E\", \"log2 fold change IC90\": -1.3999320958647967, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.03313661943683932, \"functional effect\": 0.1254, \"times_seen\": 23.0}, {\"site\": 178, \"mutant\": \"H\", \"log2 fold change IC90\": 0.08782770470884577, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.09293269387526255, \"functional effect\": -0.0332, \"times_seen\": 102.0}, {\"site\": 178, \"mutant\": \"K\", \"log2 fold change IC90\": 0.014134071663172858, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08830484495860574, \"functional effect\": 0.0011, \"times_seen\": 13.0}, {\"site\": 178, \"mutant\": \"L\", \"log2 fold change IC90\": -0.2640181747149333, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.07282028307427114, \"functional effect\": 0.0052, \"times_seen\": 74.0}, {\"site\": 178, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 178, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0061129801883010974, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08781525023653276, \"functional effect\": -0.4437, \"times_seen\": 8.0}, {\"site\": 178, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 178, \"mutant\": \"R\", \"log2 fold change IC90\": -0.034227647290779976, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08539377332559696, \"functional effect\": 0.0312, \"times_seen\": 51.0}, {\"site\": 178, \"mutant\": \"T\", \"log2 fold change IC90\": 0.030448455445958825, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08930908733004135, \"functional effect\": 0.1608, \"times_seen\": 6.0}, {\"site\": 178, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02139198215561127, \"epitope\": \"all\", \"reference_site\": \"183\", \"IC90\": 0.08875020831753694, \"functional effect\": 0.0808, \"times_seen\": 3.0}, {\"site\": 179, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 179, \"mutant\": \"A\", \"log2 fold change IC90\": -0.018968273369689, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.086301776087741, \"functional effect\": 0.1384, \"times_seen\": 15.0}, {\"site\": 179, \"mutant\": \"C\", \"log2 fold change IC90\": 0.039920553601681515, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08989738045759073, \"functional effect\": -0.2475, \"times_seen\": 31.0}, {\"site\": 179, \"mutant\": \"D\", \"log2 fold change IC90\": 0.007168241747045928, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08787950633680479, \"functional effect\": 0.0672, \"times_seen\": 133.0}, {\"site\": 179, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 179, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": null, \"functional effect\": 0.2267, \"times_seen\": null}, {\"site\": 179, \"mutant\": \"S\", \"log2 fold change IC90\": -0.031696306966697195, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08554373602979183, \"functional effect\": 0.0312, \"times_seen\": 76.0}, {\"site\": 179, \"mutant\": \"V\", \"log2 fold change IC90\": -0.018542628302459094, \"epitope\": \"all\", \"reference_site\": \"184\", \"IC90\": 0.08632724186094153, \"functional effect\": 0.0414, \"times_seen\": 49.0}, {\"site\": 180, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 180, \"mutant\": \"D\", \"log2 fold change IC90\": 0.036989683368580405, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08971493711402177, \"functional effect\": 0.0329, \"times_seen\": 49.0}, {\"site\": 180, \"mutant\": \"I\", \"log2 fold change IC90\": -0.19924095975954167, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.07616443899937689, \"functional effect\": 0.0399, \"times_seen\": 38.0}, {\"site\": 180, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02086577912186642, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.0861883422243008, \"functional effect\": -0.0217, \"times_seen\": 24.0}, {\"site\": 180, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 180, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0689510173039023, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08336301787242562, \"functional effect\": -0.0815, \"times_seen\": 66.0}, {\"site\": 180, \"mutant\": \"T\", \"log2 fold change IC90\": 0.031023384335878243, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08934468501726739, \"functional effect\": 0.027, \"times_seen\": 16.0}, {\"site\": 180, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0490804433587244, \"epitope\": \"all\", \"reference_site\": \"185\", \"IC90\": 0.08451913957322357, \"functional effect\": 0.0688, \"times_seen\": 28.0}, {\"site\": 181, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 181, \"mutant\": \"C\", \"log2 fold change IC90\": -0.00459008382439055, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08716617722516727, \"functional effect\": -0.1598, \"times_seen\": 1.0}, {\"site\": 181, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 181, \"mutant\": \"I\", \"log2 fold change IC90\": 0.009001666069716172, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08799125749818215, \"functional effect\": -0.0153, \"times_seen\": 24.0}, {\"site\": 181, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0686494254342222, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.09170548014650562, \"functional effect\": -0.0256, \"times_seen\": 44.0}, {\"site\": 181, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04657320587255688, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.09031287854638867, \"functional effect\": -0.0144, \"times_seen\": 46.0}, {\"site\": 181, \"mutant\": \"V\", \"log2 fold change IC90\": -0.023267359472046573, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.08604498826697984, \"functional effect\": -0.0381, \"times_seen\": 13.0}, {\"site\": 181, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007459536686809706, \"epitope\": \"all\", \"reference_site\": \"186\", \"IC90\": 0.0869929800790158, \"functional effect\": 0.0674, \"times_seen\": 2.0}, {\"site\": 182, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 182, \"mutant\": \"E\", \"log2 fold change IC90\": 0.536697112556223, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.12685035363452013, \"functional effect\": 0.0127, \"times_seen\": 50.0}, {\"site\": 182, \"mutant\": \"I\", \"log2 fold change IC90\": 0.05026360544268198, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.09054419371656698, \"functional effect\": 0.1137, \"times_seen\": 18.0}, {\"site\": 182, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 182, \"mutant\": \"M\", \"log2 fold change IC90\": 0.002060741128770377, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.08756894100873329, \"functional effect\": 0.3116, \"times_seen\": 2.0}, {\"site\": 182, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0036596214122836743, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.08722241295691979, \"functional effect\": 0.1255, \"times_seen\": 27.0}, {\"site\": 182, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.007429149642563764, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.08789540056934213, \"functional effect\": 0.1238, \"times_seen\": 22.0}, {\"site\": 182, \"mutant\": \"R\", \"log2 fold change IC90\": 0.8671793021263067, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.15950589356350442, \"functional effect\": -0.0472, \"times_seen\": 36.0}, {\"site\": 182, \"mutant\": \"T\", \"log2 fold change IC90\": 0.010348458595269689, \"epitope\": \"all\", \"reference_site\": \"187\", \"IC90\": 0.08807343792851341, \"functional effect\": -0.0964, \"times_seen\": 3.0}, {\"site\": 183, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": null, \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 183, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 183, \"mutant\": \"D\", \"log2 fold change IC90\": -0.020870358776148068, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.08618806863066332, \"functional effect\": -0.1389, \"times_seen\": 15.0}, {\"site\": 183, \"mutant\": \"I\", \"log2 fold change IC90\": 0.037603912819063515, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.08975314150736946, \"functional effect\": 0.0499, \"times_seen\": 9.0}, {\"site\": 183, \"mutant\": \"K\", \"log2 fold change IC90\": 0.05904316892230737, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.0910968830922194, \"functional effect\": 0.012, \"times_seen\": 18.0}, {\"site\": 183, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 183, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06398683534926604, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.08365035647747157, \"functional effect\": 0.1074, \"times_seen\": 73.0}, {\"site\": 183, \"mutant\": \"T\", \"log2 fold change IC90\": 0.034266107066072325, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.08954572950439724, \"functional effect\": 0.2032, \"times_seen\": 18.0}, {\"site\": 183, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.1218711338907529, \"epitope\": \"all\", \"reference_site\": \"188\", \"IC90\": 0.0803605473081182, \"functional effect\": 0.0384, \"times_seen\": 62.0}, {\"site\": 184, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 184, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0325442098724666, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08549347490742581, \"functional effect\": 0.1499, \"times_seen\": 25.0}, {\"site\": 184, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01960553669456189, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08626366352032448, \"functional effect\": 0.1391, \"times_seen\": 11.0}, {\"site\": 184, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 184, \"mutant\": \"M\", \"log2 fold change IC90\": -0.014163577878013069, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08658967129999429, \"functional effect\": 0.143, \"times_seen\": 3.0}, {\"site\": 184, \"mutant\": \"P\", \"log2 fold change IC90\": -0.016829140201180582, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08642983359031264, \"functional effect\": -2.8453, \"times_seen\": 5.0}, {\"site\": 184, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0009210662235926467, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08738813768471178, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 184, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": null, \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 184, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005467089816825176, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": 0.08711320551112554, \"functional effect\": -0.9961, \"times_seen\": 1.0}, {\"site\": 184, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"189\", \"IC90\": null, \"functional effect\": -0.8023, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03701116971514022, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08522917421081957, \"functional effect\": -0.0488, \"times_seen\": 25.0}, {\"site\": 185, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04038723651616534, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08992646516130733, \"functional effect\": -0.184, \"times_seen\": 4.0}, {\"site\": 185, \"mutant\": \"K\", \"log2 fold change IC90\": -0.016119193404097273, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08647237597242789, \"functional effect\": -0.0704, \"times_seen\": 28.0}, {\"site\": 185, \"mutant\": \"M\", \"log2 fold change IC90\": 0.13792232389835454, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.09621626838653331, \"functional effect\": -0.2213, \"times_seen\": 35.0}, {\"site\": 185, \"mutant\": \"N\", \"log2 fold change IC90\": 0.013356984893460745, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.08825729364154553, \"functional effect\": 0.0191, \"times_seen\": 8.0}, {\"site\": 185, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"S\", \"log2 fold change IC90\": 0.15398126135442233, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.09729325456589334, \"functional effect\": -0.0367, \"times_seen\": 42.0}, {\"site\": 185, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 185, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004133700349336209, \"epitope\": \"all\", \"reference_site\": \"190\", \"IC90\": 0.0871937558156637, \"functional effect\": 0.0793, \"times_seen\": 17.0}, {\"site\": 186, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0002431984138489644, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.0874586889656202, \"functional effect\": -1.3138, \"times_seen\": 1.0}, {\"site\": 186, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 186, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0028737613464917015, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08726993740340962, \"functional effect\": -2.6406, \"times_seen\": 1.0}, {\"site\": 186, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 186, \"mutant\": \"G\", \"log2 fold change IC90\": 0.029421387740800494, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08924553000568329, \"functional effect\": -2.9466, \"times_seen\": 4.0}, {\"site\": 186, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": null, \"functional effect\": -2.487, \"times_seen\": null}, {\"site\": 186, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004769934373705499, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08715531151391924, \"functional effect\": -1.0278, \"times_seen\": 1.0}, {\"site\": 186, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009181895227687585, \"epitope\": \"all\", \"reference_site\": \"191\", \"IC90\": 0.08688918565635488, \"functional effect\": -1.948, \"times_seen\": 4.0}, {\"site\": 187, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 187, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": null, \"functional effect\": -0.7, \"times_seen\": null}, {\"site\": 187, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 187, \"mutant\": \"I\", \"log2 fold change IC90\": 0.021357968245197624, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.08874811590994994, \"functional effect\": -0.3386, \"times_seen\": 4.0}, {\"site\": 187, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0959798292366432, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.08181575552967019, \"functional effect\": -0.2058, \"times_seen\": 24.0}, {\"site\": 187, \"mutant\": \"S\", \"log2 fold change IC90\": -0.010844714015840005, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.08678909677029183, \"functional effect\": -0.8613, \"times_seen\": 2.0}, {\"site\": 187, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.016515791962169957, \"epitope\": \"all\", \"reference_site\": \"192\", \"IC90\": 0.08845074630023315, \"functional effect\": -0.2117, \"times_seen\": 12.0}, {\"site\": 188, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": null, \"functional effect\": -0.134, \"times_seen\": null}, {\"site\": 188, \"mutant\": \"A\", \"log2 fold change IC90\": -0.006771666536788201, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08703446780893306, \"functional effect\": 0.1895, \"times_seen\": 1.0}, {\"site\": 188, \"mutant\": \"C\", \"log2 fold change IC90\": -0.010586769101224825, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08680461550914628, \"functional effect\": -0.3795, \"times_seen\": 12.0}, {\"site\": 188, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": null, \"functional effect\": -3.0012, \"times_seen\": null}, {\"site\": 188, \"mutant\": \"L\", \"log2 fold change IC90\": -0.09426860228564642, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08191285740300804, \"functional effect\": 0.1124, \"times_seen\": 43.0}, {\"site\": 188, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0497584027611255, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.08447943119248917, \"functional effect\": -0.4666, \"times_seen\": 15.0}, {\"site\": 188, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": null, \"functional effect\": -1.0815, \"times_seen\": null}, {\"site\": 188, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"193\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0071075891028183225, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08701420473365609, \"functional effect\": -0.6875, \"times_seen\": 3.0}, {\"site\": 189, \"mutant\": \"L\", \"log2 fold change IC90\": -0.023746980175094898, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08601638755964307, \"functional effect\": -0.1861, \"times_seen\": 7.0}, {\"site\": 189, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0007379608768107675, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.08748868747242644, \"functional effect\": -1.0215, \"times_seen\": 1.0}, {\"site\": 189, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": null, \"functional effect\": -2.9593, \"times_seen\": null}, {\"site\": 189, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05242505311101536, \"epitope\": \"all\", \"reference_site\": \"194\", \"IC90\": 0.0843234252261502, \"functional effect\": -0.537, \"times_seen\": 6.0}, {\"site\": 190, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": null, \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 190, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0118986602361622, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.08672571702999382, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 190, \"mutant\": \"N\", \"log2 fold change IC90\": -0.022021771052029994, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.08611930953248657, \"functional effect\": -1.997, \"times_seen\": 3.0}, {\"site\": 190, \"mutant\": \"R\", \"log2 fold change IC90\": -0.3672975565886046, \"epitope\": \"all\", \"reference_site\": \"195\", \"IC90\": 0.0677894594620527, \"functional effect\": -0.7651, \"times_seen\": 42.0}, {\"site\": 191, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": null, \"functional effect\": -0.2707, \"times_seen\": null}, {\"site\": 191, \"mutant\": \"D\", \"log2 fold change IC90\": -0.006963896349589661, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08702287179979326, \"functional effect\": -0.2374, \"times_seen\": 1.0}, {\"site\": 191, \"mutant\": \"E\", \"log2 fold change IC90\": 0.017263021470083715, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08849657034815828, \"functional effect\": 0.2717, \"times_seen\": 7.0}, {\"site\": 191, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 191, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03596981108160389, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.0852907160984745, \"functional effect\": 0.3306, \"times_seen\": 16.0}, {\"site\": 191, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01841947305859316, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08633461147546102, \"functional effect\": -0.752, \"times_seen\": 4.0}, {\"site\": 191, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 191, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0006083872303600651, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08740707959232118, \"functional effect\": 0.249, \"times_seen\": 9.0}, {\"site\": 191, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0364109948489074, \"epitope\": \"all\", \"reference_site\": \"196\", \"IC90\": 0.08526463773443402, \"functional effect\": 0.3514, \"times_seen\": 10.0}, {\"site\": 192, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 192, \"mutant\": \"L\", \"log2 fold change IC90\": 0.019402938877169453, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08862793273838665, \"functional effect\": 0.4293, \"times_seen\": 14.0}, {\"site\": 192, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02336979129578876, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08603887926130624, \"functional effect\": 0.0857, \"times_seen\": 11.0}, {\"site\": 192, \"mutant\": \"N\", \"log2 fold change IC90\": 0.007978829845898542, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08792889591351867, \"functional effect\": 0.1366, \"times_seen\": 2.0}, {\"site\": 192, \"mutant\": \"S\", \"log2 fold change IC90\": -1.6200378574763844e-05, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08744296517214058, \"functional effect\": -0.33, \"times_seen\": 9.0}, {\"site\": 192, \"mutant\": \"T\", \"log2 fold change IC90\": 0.009562525472290374, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.08802547146350649, \"functional effect\": -0.0423, \"times_seen\": 34.0}, {\"site\": 192, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03623246905919823, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.0896678616008066, \"functional effect\": -0.1628, \"times_seen\": 19.0}, {\"site\": 192, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.005982292201703605, \"epitope\": \"all\", \"reference_site\": \"197\", \"IC90\": 0.087807295763733, \"functional effect\": -0.0628, \"times_seen\": 7.0}, {\"site\": 193, \"mutant\": \"A\", \"log2 fold change IC90\": 0.01388298933362146, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08828947798477497, \"functional effect\": -0.1032, \"times_seen\": 14.0}, {\"site\": 193, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 193, \"mutant\": \"E\", \"log2 fold change IC90\": 0.4658754267041672, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.12077366079946028, \"functional effect\": -0.3554, \"times_seen\": 10.0}, {\"site\": 193, \"mutant\": \"G\", \"log2 fold change IC90\": 0.09874359805593613, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.09363851932386723, \"functional effect\": -0.0112, \"times_seen\": 29.0}, {\"site\": 193, \"mutant\": \"H\", \"log2 fold change IC90\": 0.009890508071433645, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08804548546792275, \"functional effect\": 0.041, \"times_seen\": 24.0}, {\"site\": 193, \"mutant\": \"M\", \"log2 fold change IC90\": -0.006845602479101723, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08703000753817572, \"functional effect\": 0.0024, \"times_seen\": 16.0}, {\"site\": 193, \"mutant\": \"N\", \"log2 fold change IC90\": -0.11454682497402559, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08076956103625992, \"functional effect\": 0.3645, \"times_seen\": 14.0}, {\"site\": 193, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": null, \"functional effect\": -2.9276, \"times_seen\": null}, {\"site\": 193, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.014033150485607826, \"epitope\": \"all\", \"reference_site\": \"198\", \"IC90\": 0.08829866796555662, \"functional effect\": -0.081, \"times_seen\": 14.0}, {\"site\": 194, \"mutant\": \"A\", \"log2 fold change IC90\": -0.05624492531903977, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08410045456932046, \"functional effect\": -0.2591, \"times_seen\": 11.0}, {\"site\": 194, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04514548813935113, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08474998045627251, \"functional effect\": -1.1385, \"times_seen\": 43.0}, {\"site\": 194, \"mutant\": \"D\", \"log2 fold change IC90\": 0.02643863005186199, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08906120636680519, \"functional effect\": -0.8634, \"times_seen\": 41.0}, {\"site\": 194, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 194, \"mutant\": \"R\", \"log2 fold change IC90\": -0.07612341511045781, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08294960485036809, \"functional effect\": -0.7793, \"times_seen\": 9.0}, {\"site\": 194, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06233291049173964, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08374630935334464, \"functional effect\": -0.2356, \"times_seen\": 23.0}, {\"site\": 194, \"mutant\": \"V\", \"log2 fold change IC90\": -0.07445038902498978, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08304585343124656, \"functional effect\": -0.9871, \"times_seen\": 33.0}, {\"site\": 194, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004848500386659529, \"epitope\": \"all\", \"reference_site\": \"199\", \"IC90\": 0.08715056535572621, \"functional effect\": -0.2722, \"times_seen\": 4.0}, {\"site\": 195, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": null, \"functional effect\": -2.8839, \"times_seen\": null}, {\"site\": 195, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006055027560376782, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.087077711726747, \"functional effect\": 0.2463, \"times_seen\": 39.0}, {\"site\": 195, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0038913044959924363, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08768012336718518, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 195, \"mutant\": \"F\", \"log2 fold change IC90\": 0.007917415451335785, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08792515292916184, \"functional effect\": 0.4444, \"times_seen\": 13.0}, {\"site\": 195, \"mutant\": \"H\", \"log2 fold change IC90\": 0.6356638393114206, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.13585750532277402, \"functional effect\": 0.1067, \"times_seen\": 58.0}, {\"site\": 195, \"mutant\": \"I\", \"log2 fold change IC90\": -0.08463796948867919, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08246149140786546, \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 195, \"mutant\": \"L\", \"log2 fold change IC90\": -0.034201428181184344, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08539532526067906, \"functional effect\": 0.338, \"times_seen\": 8.0}, {\"site\": 195, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007754983150766361, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08697516679478089, \"functional effect\": 0.0289, \"times_seen\": 6.0}, {\"site\": 195, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.001769455314978235, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.08733676345396778, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 195, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"200\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 196, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 196, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004409867391222324, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.0871770664001425, \"functional effect\": 0.1425, \"times_seen\": 1.0}, {\"site\": 196, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04364873136523291, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08483795187662338, \"functional effect\": 0.3392, \"times_seen\": 14.0}, {\"site\": 196, \"mutant\": \"S\", \"log2 fold change IC90\": -0.017200640406984553, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08640758040003561, \"functional effect\": -1.9717, \"times_seen\": 3.0}, {\"site\": 196, \"mutant\": \"V\", \"log2 fold change IC90\": 0.013862840966863176, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": 0.08828824496164035, \"functional effect\": 0.255, \"times_seen\": 1.0}, {\"site\": 196, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"201\", \"IC90\": null, \"functional effect\": -0.6135, \"times_seen\": null}, {\"site\": 197, \"mutant\": \"E\", \"log2 fold change IC90\": 0.003390396011383659, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.08764968582298603, \"functional effect\": -0.5772, \"times_seen\": 8.0}, {\"site\": 197, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": null, \"functional effect\": -0.5056, \"times_seen\": null}, {\"site\": 197, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 197, \"mutant\": \"M\", \"log2 fold change IC90\": -0.020396880587077677, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.08621635934120768, \"functional effect\": -0.2777, \"times_seen\": 4.0}, {\"site\": 197, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03705385807129104, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.08522665237535659, \"functional effect\": -0.3112, \"times_seen\": 29.0}, {\"site\": 197, \"mutant\": \"R\", \"log2 fold change IC90\": -1.8773404950180517, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.02380093135326973, \"functional effect\": 0.0764, \"times_seen\": 49.0}, {\"site\": 197, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0421975292064253, \"epitope\": \"all\", \"reference_site\": \"202\", \"IC90\": 0.08492333302626973, \"functional effect\": 0.0004, \"times_seen\": 6.0}, {\"site\": 198, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 198, \"mutant\": \"L\", \"log2 fold change IC90\": 0.05054477486016076, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.09056184175613576, \"functional effect\": -0.2275, \"times_seen\": 46.0}, {\"site\": 198, \"mutant\": \"M\", \"log2 fold change IC90\": 0.04516527392256031, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.09022478483390156, \"functional effect\": -0.3953, \"times_seen\": 67.0}, {\"site\": 198, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 198, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07554606964970288, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.08298280671237433, \"functional effect\": -0.445, \"times_seen\": 20.0}, {\"site\": 198, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1517353128010264, \"epitope\": \"all\", \"reference_site\": \"203\", \"IC90\": 0.07871416127637551, \"functional effect\": -0.0588, \"times_seen\": 58.0}, {\"site\": 199, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": null, \"functional effect\": -2.2239, \"times_seen\": null}, {\"site\": 199, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0008727157299822351, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.0874968597302616, \"functional effect\": -0.7565, \"times_seen\": 17.0}, {\"site\": 199, \"mutant\": \"F\", \"log2 fold change IC90\": -0.48127596808085127, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.06263992805460777, \"functional effect\": -0.0822, \"times_seen\": 41.0}, {\"site\": 199, \"mutant\": \"H\", \"log2 fold change IC90\": 0.1581360494265665, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.09757385127708072, \"functional effect\": -0.164, \"times_seen\": 65.0}, {\"site\": 199, \"mutant\": \"L\", \"log2 fold change IC90\": 1.307773761012316, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.21647556530289722, \"functional effect\": 0.0432, \"times_seen\": 13.0}, {\"site\": 199, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0028741644725194804, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.08761832823420924, \"functional effect\": 0.1136, \"times_seen\": 1.0}, {\"site\": 199, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"204\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 200, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03399087771298112, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.0854077889742809, \"functional effect\": 0.0281, \"times_seen\": 10.0}, {\"site\": 200, \"mutant\": \"C\", \"log2 fold change IC90\": -0.011953871672986088, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08672239813051062, \"functional effect\": -0.0198, \"times_seen\": 3.0}, {\"site\": 200, \"mutant\": \"F\", \"log2 fold change IC90\": -0.20324525166303947, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.07595333285639047, \"functional effect\": -0.1648, \"times_seen\": 49.0}, {\"site\": 200, \"mutant\": \"G\", \"log2 fold change IC90\": -0.10716003819797733, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08118417224928036, \"functional effect\": -0.2185, \"times_seen\": 26.0}, {\"site\": 200, \"mutant\": \"I\", \"log2 fold change IC90\": 0.4756693043214215, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.12159633395049649, \"functional effect\": 0.0784, \"times_seen\": 31.0}, {\"site\": 200, \"mutant\": \"N\", \"log2 fold change IC90\": -0.060850951441769004, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.0838323790787642, \"functional effect\": -0.0072, \"times_seen\": 19.0}, {\"site\": 200, \"mutant\": \"R\", \"log2 fold change IC90\": -0.008267608511216456, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08694426784891617, \"functional effect\": 0.0049, \"times_seen\": 5.0}, {\"site\": 200, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 200, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": null, \"functional effect\": -0.681, \"times_seen\": null}, {\"site\": 200, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04312974213881834, \"epitope\": \"all\", \"reference_site\": \"205\", \"IC90\": 0.08486847662530543, \"functional effect\": 0.0358, \"times_seen\": 16.0}, {\"site\": 201, \"mutant\": \"A\", \"log2 fold change IC90\": 0.08557060926282015, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.0927874144110427, \"functional effect\": -0.1606, \"times_seen\": 6.0}, {\"site\": 201, \"mutant\": \"E\", \"log2 fold change IC90\": 0.026578793203843893, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08906985941229235, \"functional effect\": -0.6104, \"times_seen\": 9.0}, {\"site\": 201, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 201, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004678413829340184, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08716084057885455, \"functional effect\": 0.1011, \"times_seen\": 1.0}, {\"site\": 201, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 201, \"mutant\": \"L\", \"log2 fold change IC90\": -0.02589969334617333, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08588813416965264, \"functional effect\": -0.0949, \"times_seen\": 8.0}, {\"site\": 201, \"mutant\": \"M\", \"log2 fold change IC90\": 0.024363943959397092, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08893322280387955, \"functional effect\": -0.6998, \"times_seen\": 10.0}, {\"site\": 201, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004229670163950922, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08718795577474964, \"functional effect\": -0.9007, \"times_seen\": 9.0}, {\"site\": 201, \"mutant\": \"R\", \"log2 fold change IC90\": 0.07737255574939687, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.09226164908987021, \"functional effect\": -0.2913, \"times_seen\": 27.0}, {\"site\": 201, \"mutant\": \"T\", \"log2 fold change IC90\": -0.018361811697955855, \"epitope\": \"all\", \"reference_site\": \"206\", \"IC90\": 0.08633806214972779, \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 202, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0025203367364658447, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08729131899893484, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 202, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 202, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0015611196659655422, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08753862015349288, \"functional effect\": -0.0465, \"times_seen\": 10.0}, {\"site\": 202, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": null, \"functional effect\": -0.3132, \"times_seen\": null}, {\"site\": 202, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0036449849342588456, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08722329785315233, \"functional effect\": -0.0726, \"times_seen\": 19.0}, {\"site\": 202, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05920236382122861, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08392823025514888, \"functional effect\": -0.0033, \"times_seen\": 12.0}, {\"site\": 202, \"mutant\": \"R\", \"log2 fold change IC90\": 0.1051721046370132, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.094056694296879, \"functional effect\": 0.0603, \"times_seen\": 25.0}, {\"site\": 202, \"mutant\": \"S\", \"log2 fold change IC90\": 0.012672809082748947, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.0882154489078986, \"functional effect\": -0.1124, \"times_seen\": 6.0}, {\"site\": 202, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.028160270838311532, \"epitope\": \"all\", \"reference_site\": \"207\", \"IC90\": 0.08575366032488285, \"functional effect\": -0.0474, \"times_seen\": 70.0}, {\"site\": 203, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0778696475006066, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08284926371416663, \"functional effect\": -0.0387, \"times_seen\": 44.0}, {\"site\": 203, \"mutant\": \"I\", \"log2 fold change IC90\": -0.10194520472074466, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.0814781553863993, \"functional effect\": -0.0312, \"times_seen\": 41.0}, {\"site\": 203, \"mutant\": \"K\", \"log2 fold change IC90\": -0.013368879210877982, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08663738176575472, \"functional effect\": -0.1878, \"times_seen\": 17.0}, {\"site\": 203, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0076970521862646905, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08697865932530152, \"functional effect\": -0.0927, \"times_seen\": 6.0}, {\"site\": 203, \"mutant\": \"M\", \"log2 fold change IC90\": 0.082409786743474, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.0925843475851419, \"functional effect\": -0.0399, \"times_seen\": 38.0}, {\"site\": 203, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": null, \"functional effect\": -0.2688, \"times_seen\": null}, {\"site\": 203, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02263741969285554, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.08882685692406936, \"functional effect\": -0.2993, \"times_seen\": 11.0}, {\"site\": 203, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"208\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 204, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": null, \"functional effect\": 0.2366, \"times_seen\": null}, {\"site\": 204, \"mutant\": \"H\", \"log2 fold change IC90\": 0.07144313156409404, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.09188323523150917, \"functional effect\": 0.2003, \"times_seen\": 63.0}, {\"site\": 204, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0039855920620791956, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08720270765952337, \"functional effect\": 0.045, \"times_seen\": 55.0}, {\"site\": 204, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 204, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0024561740105587928, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.0875929463485662, \"functional effect\": 0.0731, \"times_seen\": 6.0}, {\"site\": 204, \"mutant\": \"R\", \"log2 fold change IC90\": -0.06076449038275726, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08383740332385259, \"functional effect\": 0.0513, \"times_seen\": 14.0}, {\"site\": 204, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0012123100139020977, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08737049800139994, \"functional effect\": -0.0455, \"times_seen\": 33.0}, {\"site\": 204, \"mutant\": \"T\", \"log2 fold change IC90\": 0.02122710551896552, \"epitope\": \"all\", \"reference_site\": \"209\", \"IC90\": 0.08874006618817606, \"functional effect\": 0.1251, \"times_seen\": 29.0}, {\"site\": 205, \"mutant\": \"-\", \"log2 fold change IC90\": -0.08346519964310947, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08252855178144834, \"functional effect\": -0.0943, \"times_seen\": 21.0}, {\"site\": 205, \"mutant\": \"F\", \"log2 fold change IC90\": -0.00984549544596844, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.0868492282003234, \"functional effect\": 0.0024, \"times_seen\": 33.0}, {\"site\": 205, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 205, \"mutant\": \"L\", \"log2 fold change IC90\": -0.024078349607347053, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08599663291466667, \"functional effect\": 0.0427, \"times_seen\": 4.0}, {\"site\": 205, \"mutant\": \"N\", \"log2 fold change IC90\": -0.002337253224312887, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08730239730371571, \"functional effect\": 0.1542, \"times_seen\": 6.0}, {\"site\": 205, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": null, \"functional effect\": -3.1276, \"times_seen\": null}, {\"site\": 205, \"mutant\": \"T\", \"log2 fold change IC90\": 1.0202445409410168, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.1773592985783708, \"functional effect\": 0.0091, \"times_seen\": 66.0}, {\"site\": 205, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0002231744823757438, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08743042119668686, \"functional effect\": -0.0732, \"times_seen\": 28.0}, {\"site\": 205, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.047802271972813754, \"epitope\": \"all\", \"reference_site\": \"210\", \"IC90\": 0.08459405340600905, \"functional effect\": -0.0985, \"times_seen\": 21.0}, {\"site\": 206, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0002882999636629658, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0874264745415842, \"functional effect\": -2.7994, \"times_seen\": 4.0}, {\"site\": 206, \"mutant\": \"A\", \"log2 fold change IC90\": -2.697579701618864, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.013479610615305532, \"functional effect\": -0.0728, \"times_seen\": 122.0}, {\"site\": 206, \"mutant\": \"C\", \"log2 fold change IC90\": 0.15948978367696826, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0976654514088435, \"functional effect\": -0.0454, \"times_seen\": 97.0}, {\"site\": 206, \"mutant\": \"D\", \"log2 fold change IC90\": -0.41736632116933425, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.06547718063547874, \"functional effect\": 0.0567, \"times_seen\": 102.0}, {\"site\": 206, \"mutant\": \"E\", \"log2 fold change IC90\": -0.08789010300854395, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08227581547648628, \"functional effect\": -0.065, \"times_seen\": 42.0}, {\"site\": 206, \"mutant\": \"F\", \"log2 fold change IC90\": -0.019545429168365082, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08626725762946305, \"functional effect\": 0.0738, \"times_seen\": 149.0}, {\"site\": 206, \"mutant\": \"G\", \"log2 fold change IC90\": 0.12437703329362494, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.09531713293173331, \"functional effect\": -0.0576, \"times_seen\": 81.0}, {\"site\": 206, \"mutant\": \"H\", \"log2 fold change IC90\": -0.7712951492389751, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.05123264494249794, \"functional effect\": -0.0446, \"times_seen\": 96.0}, {\"site\": 206, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 206, \"mutant\": \"K\", \"log2 fold change IC90\": 0.019670270359072258, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08864435702156608, \"functional effect\": 0.0143, \"times_seen\": 34.0}, {\"site\": 206, \"mutant\": \"L\", \"log2 fold change IC90\": -0.5026405391496069, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.06171914107547571, \"functional effect\": 0.0161, \"times_seen\": 133.0}, {\"site\": 206, \"mutant\": \"M\", \"log2 fold change IC90\": -0.08246980264437662, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08258551255032408, \"functional effect\": 0.0034, \"times_seen\": 32.0}, {\"site\": 206, \"mutant\": \"N\", \"log2 fold change IC90\": 0.1403752465272166, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.09637999793876273, \"functional effect\": 0.0533, \"times_seen\": 96.0}, {\"site\": 206, \"mutant\": \"P\", \"log2 fold change IC90\": 0.8399982751637747, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.1565288627635491, \"functional effect\": 0.0835, \"times_seen\": 89.0}, {\"site\": 206, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.35452518779111614, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.06839227291171067, \"functional effect\": -0.1415, \"times_seen\": 24.0}, {\"site\": 206, \"mutant\": \"R\", \"log2 fold change IC90\": -0.43015710277254093, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.06489923267757154, \"functional effect\": 0.0084, \"times_seen\": 153.0}, {\"site\": 206, \"mutant\": \"S\", \"log2 fold change IC90\": -0.14486161938931294, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.07909008825598679, \"functional effect\": -0.0246, \"times_seen\": 308.0}, {\"site\": 206, \"mutant\": \"T\", \"log2 fold change IC90\": 0.059472102772248424, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.09112397152391115, \"functional effect\": 0.052, \"times_seen\": 149.0}, {\"site\": 206, \"mutant\": \"V\", \"log2 fold change IC90\": -0.09864619913762308, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.08166468437882465, \"functional effect\": 0.0672, \"times_seen\": 149.0}, {\"site\": 206, \"mutant\": \"W\", \"log2 fold change IC90\": -0.027779762924196347, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0857762806631475, \"functional effect\": 0.0393, \"times_seen\": 25.0}, {\"site\": 206, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.08930320784316745, \"epitope\": \"all\", \"reference_site\": \"212\", \"IC90\": 0.0930277885567422, \"functional effect\": 0.0431, \"times_seen\": 81.0}, {\"site\": 207, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0704656227813171, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08327554558942993, \"functional effect\": 0.0563, \"times_seen\": 71.0}, {\"site\": 207, \"mutant\": \"E\", \"log2 fold change IC90\": 0.12669837152815158, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.09547062442082799, \"functional effect\": 0.0368, \"times_seen\": 30.0}, {\"site\": 207, \"mutant\": \"F\", \"log2 fold change IC90\": -0.053538326943845166, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08425838109033798, \"functional effect\": -0.0004, \"times_seen\": 25.0}, {\"site\": 207, \"mutant\": \"G\", \"log2 fold change IC90\": 0.039210598076187986, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08985315250993078, \"functional effect\": 0.0089, \"times_seen\": 17.0}, {\"site\": 207, \"mutant\": \"L\", \"log2 fold change IC90\": -0.5292705146555169, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.06059034872862637, \"functional effect\": -0.0977, \"times_seen\": 82.0}, {\"site\": 207, \"mutant\": \"M\", \"log2 fold change IC90\": -0.2854672767309223, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.071745644249054, \"functional effect\": 0.0099, \"times_seen\": 99.0}, {\"site\": 207, \"mutant\": \"P\", \"log2 fold change IC90\": 0.008180942950924287, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.08794121509849966, \"functional effect\": 0.1557, \"times_seen\": 5.0}, {\"site\": 207, \"mutant\": \"R\", \"log2 fold change IC90\": 1.8357081907972264, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.3121281810870986, \"functional effect\": 0.0342, \"times_seen\": 27.0}, {\"site\": 207, \"mutant\": \"S\", \"log2 fold change IC90\": 0.8792951308628473, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.16085107297401335, \"functional effect\": -0.1629, \"times_seen\": 16.0}, {\"site\": 207, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"213\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"-\", \"log2 fold change IC90\": -0.036020392892570204, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08528772580383225, \"functional effect\": 0.1074, \"times_seen\": 19.0}, {\"site\": 208, \"mutant\": \"A\", \"log2 fold change IC90\": 0.015003618570527918, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0883580844495955, \"functional effect\": -0.0533, \"times_seen\": 4.0}, {\"site\": 208, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0746875746718165, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.09209010180999248, \"functional effect\": -0.2796, \"times_seen\": 16.0}, {\"site\": 208, \"mutant\": \"E\", \"log2 fold change IC90\": -0.015357702911839835, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0865180303009024, \"functional effect\": -0.0487, \"times_seen\": 5.0}, {\"site\": 208, \"mutant\": \"G\", \"log2 fold change IC90\": -0.046217153161937766, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08468704971717932, \"functional effect\": 0.2323, \"times_seen\": 16.0}, {\"site\": 208, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03669732655579604, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0896967585558871, \"functional effect\": 0.1525, \"times_seen\": 10.0}, {\"site\": 208, \"mutant\": \"I\", \"log2 fold change IC90\": 0.08141522462233998, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0925205439741663, \"functional effect\": 0.1284, \"times_seen\": 13.0}, {\"site\": 208, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0004517030551166504, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08747132979396964, \"functional effect\": -0.0091, \"times_seen\": 5.0}, {\"site\": 208, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03415806566106648, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08539789199311686, \"functional effect\": 0.0282, \"times_seen\": 17.0}, {\"site\": 208, \"mutant\": \"M\", \"log2 fold change IC90\": 0.03550753484198858, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08962281606427683, \"functional effect\": -0.4161, \"times_seen\": 4.0}, {\"site\": 208, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02182190443267053, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08877665976868873, \"functional effect\": -0.0108, \"times_seen\": 1.0}, {\"site\": 208, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"S\", \"log2 fold change IC90\": -0.011500404570384998, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08674966095083533, \"functional effect\": 0.0509, \"times_seen\": 33.0}, {\"site\": 208, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": null, \"functional effect\": -3.0402, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": null, \"functional effect\": -0.031, \"times_seen\": null}, {\"site\": 208, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03455106635599304, \"epitope\": \"all\", \"reference_site\": \"214\", \"IC90\": 0.08537463215013358, \"functional effect\": 0.0297, \"times_seen\": 8.0}, {\"site\": 209, \"mutant\": \"*\", \"log2 fold change IC90\": 0.023264286958031302, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08886546158161474, \"functional effect\": -2.8369, \"times_seen\": 2.0}, {\"site\": 209, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": null, \"functional effect\": -3.0075, \"times_seen\": null}, {\"site\": 209, \"mutant\": \"A\", \"log2 fold change IC90\": -0.24582556930294228, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07374437220348806, \"functional effect\": -0.0425, \"times_seen\": 111.0}, {\"site\": 209, \"mutant\": \"C\", \"log2 fold change IC90\": -0.3011011674279014, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07097236374290629, \"functional effect\": -0.283, \"times_seen\": 29.0}, {\"site\": 209, \"mutant\": \"D\", \"log2 fold change IC90\": -0.05948193708637989, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08391196776352489, \"functional effect\": -0.0912, \"times_seen\": 81.0}, {\"site\": 209, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 209, \"mutant\": \"F\", \"log2 fold change IC90\": -0.05015599177458477, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08445615290778871, \"functional effect\": 0.016, \"times_seen\": 28.0}, {\"site\": 209, \"mutant\": \"G\", \"log2 fold change IC90\": -0.5858749458088692, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.058259106595311395, \"functional effect\": -0.0477, \"times_seen\": 115.0}, {\"site\": 209, \"mutant\": \"H\", \"log2 fold change IC90\": -0.11569552023560666, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08070527670522598, \"functional effect\": -0.0683, \"times_seen\": 38.0}, {\"site\": 209, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04417839243951291, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08480681077483955, \"functional effect\": 0.0731, \"times_seen\": 23.0}, {\"site\": 209, \"mutant\": \"K\", \"log2 fold change IC90\": 0.3734253304499293, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.11327706251555762, \"functional effect\": -0.0464, \"times_seen\": 72.0}, {\"site\": 209, \"mutant\": \"L\", \"log2 fold change IC90\": -0.3533835908675789, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.06844641277149331, \"functional effect\": -0.0069, \"times_seen\": 118.0}, {\"site\": 209, \"mutant\": \"M\", \"log2 fold change IC90\": -0.15311176595717804, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07863909711985527, \"functional effect\": -0.0198, \"times_seen\": 34.0}, {\"site\": 209, \"mutant\": \"N\", \"log2 fold change IC90\": -0.050793593278046785, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08441883561557681, \"functional effect\": 0.0274, \"times_seen\": 42.0}, {\"site\": 209, \"mutant\": \"P\", \"log2 fold change IC90\": -0.2535148463017528, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07335237496047414, \"functional effect\": -0.019, \"times_seen\": 78.0}, {\"site\": 209, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0022571605588758152, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08730724411859778, \"functional effect\": -0.0158, \"times_seen\": 65.0}, {\"site\": 209, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0026183453692362694, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08728538911632472, \"functional effect\": 0.0711, \"times_seen\": 118.0}, {\"site\": 209, \"mutant\": \"S\", \"log2 fold change IC90\": -2.859694619383482, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.012046916327876774, \"functional effect\": 0.0461, \"times_seen\": 117.0}, {\"site\": 209, \"mutant\": \"T\", \"log2 fold change IC90\": 0.1989836871449888, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.1003759829701536, \"functional effect\": -0.0859, \"times_seen\": 81.0}, {\"site\": 209, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04410369242164891, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.08481120202462701, \"functional effect\": -0.0544, \"times_seen\": 70.0}, {\"site\": 209, \"mutant\": \"W\", \"log2 fold change IC90\": 0.050737404300832185, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.09057393443068294, \"functional effect\": 0.043, \"times_seen\": 30.0}, {\"site\": 209, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.19830128100020455, \"epitope\": \"all\", \"reference_site\": \"214a\", \"IC90\": 0.07621406377568685, \"functional effect\": -0.0822, \"times_seen\": 29.0}, {\"site\": 210, \"mutant\": \"*\", \"log2 fold change IC90\": -0.050421112906411374, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08444063399841725, \"functional effect\": -2.2306, \"times_seen\": 3.0}, {\"site\": 210, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01997700239488063, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08624145517671922, \"functional effect\": 0.0818, \"times_seen\": 89.0}, {\"site\": 210, \"mutant\": \"C\", \"log2 fold change IC90\": -0.882300374455534, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.047438491992925894, \"functional effect\": -0.1751, \"times_seen\": 43.0}, {\"site\": 210, \"mutant\": \"D\", \"log2 fold change IC90\": -0.07440451878414453, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08304849390185837, \"functional effect\": -0.0387, \"times_seen\": 29.0}, {\"site\": 210, \"mutant\": \"E\", \"log2 fold change IC90\": -0.26811806218888584, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.07261363430998306, \"functional effect\": -0.0924, \"times_seen\": 13.0}, {\"site\": 210, \"mutant\": \"F\", \"log2 fold change IC90\": 0.4118854408670025, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.11633747277862161, \"functional effect\": 0.1341, \"times_seen\": 45.0}, {\"site\": 210, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03811760454228007, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08516383512485674, \"functional effect\": -0.0187, \"times_seen\": 50.0}, {\"site\": 210, \"mutant\": \"H\", \"log2 fold change IC90\": -0.012598509111737752, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08668365673678373, \"functional effect\": -0.0759, \"times_seen\": 65.0}, {\"site\": 210, \"mutant\": \"I\", \"log2 fold change IC90\": -0.00022283626907470142, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08743044169314244, \"functional effect\": 0.1244, \"times_seen\": 35.0}, {\"site\": 210, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03403033659653496, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08953109681137025, \"functional effect\": 0.1741, \"times_seen\": 21.0}, {\"site\": 210, \"mutant\": \"L\", \"log2 fold change IC90\": -0.11785043548776516, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.0805848193620015, \"functional effect\": 0.0442, \"times_seen\": 165.0}, {\"site\": 210, \"mutant\": \"M\", \"log2 fold change IC90\": 0.13089336618470462, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.09574863300032188, \"functional effect\": -0.0042, \"times_seen\": 25.0}, {\"site\": 210, \"mutant\": \"N\", \"log2 fold change IC90\": 0.2750401780661745, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.10580960580833842, \"functional effect\": 0.0743, \"times_seen\": 46.0}, {\"site\": 210, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 210, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09812824990395692, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.09359858849882506, \"functional effect\": 0.048, \"times_seen\": 30.0}, {\"site\": 210, \"mutant\": \"R\", \"log2 fold change IC90\": -0.2916611745087454, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.07143828018250632, \"functional effect\": -0.0616, \"times_seen\": 139.0}, {\"site\": 210, \"mutant\": \"S\", \"log2 fold change IC90\": -0.023105347671292603, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.0860546514916139, \"functional effect\": -0.0353, \"times_seen\": 162.0}, {\"site\": 210, \"mutant\": \"T\", \"log2 fold change IC90\": -0.10983290260649183, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08103390251723368, \"functional effect\": -0.0405, \"times_seen\": 108.0}, {\"site\": 210, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03881248238613662, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08512282561764523, \"functional effect\": -0.0603, \"times_seen\": 33.0}, {\"site\": 210, \"mutant\": \"W\", \"log2 fold change IC90\": -0.04751932095792045, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.0846106461854821, \"functional effect\": 0.1366, \"times_seen\": 17.0}, {\"site\": 210, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.08570104662679338, \"epitope\": \"all\", \"reference_site\": \"214b\", \"IC90\": 0.08240075047946716, \"functional effect\": 0.0338, \"times_seen\": 40.0}, {\"site\": 211, \"mutant\": \"*\", \"log2 fold change IC90\": 1.0752856672678155, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.18425657433575915, \"functional effect\": -2.7538, \"times_seen\": 10.0}, {\"site\": 211, \"mutant\": \"-\", \"log2 fold change IC90\": 0.022108166388827778, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08879427672931836, \"functional effect\": -0.0252, \"times_seen\": 1.0}, {\"site\": 211, \"mutant\": \"A\", \"log2 fold change IC90\": -0.027077443894070595, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08581804761888608, \"functional effect\": 0.0406, \"times_seen\": 142.0}, {\"site\": 211, \"mutant\": \"C\", \"log2 fold change IC90\": -0.022955067747397494, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08606361593641115, \"functional effect\": 0.0276, \"times_seen\": 36.0}, {\"site\": 211, \"mutant\": \"D\", \"log2 fold change IC90\": -0.3064537303329639, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.07070953605244816, \"functional effect\": 0.0312, \"times_seen\": 120.0}, {\"site\": 211, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 211, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0028285368195650083, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08761555720128708, \"functional effect\": 0.0032, \"times_seen\": 77.0}, {\"site\": 211, \"mutant\": \"G\", \"log2 fold change IC90\": 0.3221938029245921, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.10932506693610544, \"functional effect\": 0.0664, \"times_seen\": 203.0}, {\"site\": 211, \"mutant\": \"H\", \"log2 fold change IC90\": -1.9536585165705431, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.022574593464798672, \"functional effect\": -0.0951, \"times_seen\": 43.0}, {\"site\": 211, \"mutant\": \"I\", \"log2 fold change IC90\": 0.003499220021783023, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08765629758070725, \"functional effect\": -0.135, \"times_seen\": 52.0}, {\"site\": 211, \"mutant\": \"K\", \"log2 fold change IC90\": 0.058164133872707004, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.09104139460696076, \"functional effect\": 0.0204, \"times_seen\": 105.0}, {\"site\": 211, \"mutant\": \"L\", \"log2 fold change IC90\": 0.16745947666194885, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.09820646493687354, \"functional effect\": 0.0025, \"times_seen\": 174.0}, {\"site\": 211, \"mutant\": \"M\", \"log2 fold change IC90\": -0.3154011625891266, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.07027236052677444, \"functional effect\": 0.0072, \"times_seen\": 84.0}, {\"site\": 211, \"mutant\": \"N\", \"log2 fold change IC90\": -0.3214593765671797, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.0699778891553421, \"functional effect\": -0.0045, \"times_seen\": 43.0}, {\"site\": 211, \"mutant\": \"P\", \"log2 fold change IC90\": -0.10675827039671013, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08120678390840802, \"functional effect\": -0.0316, \"times_seen\": 115.0}, {\"site\": 211, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0837534081989115, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08251206662111571, \"functional effect\": -0.0557, \"times_seen\": 81.0}, {\"site\": 211, \"mutant\": \"R\", \"log2 fold change IC90\": -0.056944127611952985, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08405970515117617, \"functional effect\": -0.0215, \"times_seen\": 184.0}, {\"site\": 211, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03435165901860898, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08538643333069396, \"functional effect\": 0.0276, \"times_seen\": 177.0}, {\"site\": 211, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02495386261914663, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08594446088385031, \"functional effect\": -0.0269, \"times_seen\": 102.0}, {\"site\": 211, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0160294643013635, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08842093487518612, \"functional effect\": -0.0171, \"times_seen\": 181.0}, {\"site\": 211, \"mutant\": \"W\", \"log2 fold change IC90\": -0.05127134624228192, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.08439088468303682, \"functional effect\": 0.0405, \"times_seen\": 71.0}, {\"site\": 211, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.6821059368829978, \"epitope\": \"all\", \"reference_site\": \"214c\", \"IC90\": 0.14030207692679575, \"functional effect\": 0.066, \"times_seen\": 63.0}, {\"site\": 212, \"mutant\": \"*\", \"log2 fold change IC90\": 0.07367730212101882, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09202563667221719, \"functional effect\": -2.5539, \"times_seen\": 3.0}, {\"site\": 212, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 212, \"mutant\": \"A\", \"log2 fold change IC90\": -0.11127990698908503, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08095266731153516, \"functional effect\": -0.1064, \"times_seen\": 201.0}, {\"site\": 212, \"mutant\": \"C\", \"log2 fold change IC90\": -0.10024687636824414, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08157412725665791, \"functional effect\": -0.2074, \"times_seen\": 59.0}, {\"site\": 212, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 212, \"mutant\": \"E\", \"log2 fold change IC90\": -0.24888585388670936, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07358810939662824, \"functional effect\": -0.0597, \"times_seen\": 127.0}, {\"site\": 212, \"mutant\": \"F\", \"log2 fold change IC90\": -0.25558949304418177, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07324696744636543, \"functional effect\": -0.1832, \"times_seen\": 51.0}, {\"site\": 212, \"mutant\": \"G\", \"log2 fold change IC90\": 0.19240729639524612, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.0999194696933011, \"functional effect\": -0.1224, \"times_seen\": 143.0}, {\"site\": 212, \"mutant\": \"H\", \"log2 fold change IC90\": 0.15975421028854955, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.0976833538140757, \"functional effect\": -0.0769, \"times_seen\": 207.0}, {\"site\": 212, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05860103657145025, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08396321952850075, \"functional effect\": 0.0437, \"times_seen\": 74.0}, {\"site\": 212, \"mutant\": \"K\", \"log2 fold change IC90\": -0.05930962814474324, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08392199042626801, \"functional effect\": -0.026, \"times_seen\": 35.0}, {\"site\": 212, \"mutant\": \"L\", \"log2 fold change IC90\": 0.10777348892524546, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09422644488637343, \"functional effect\": -0.1598, \"times_seen\": 101.0}, {\"site\": 212, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0038022635609062526, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08721378952854629, \"functional effect\": -0.1444, \"times_seen\": 34.0}, {\"site\": 212, \"mutant\": \"N\", \"log2 fold change IC90\": 0.04831642315682999, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09042207010770417, \"functional effect\": -0.0638, \"times_seen\": 226.0}, {\"site\": 212, \"mutant\": \"P\", \"log2 fold change IC90\": -0.4449701782912052, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.06423627992566991, \"functional effect\": -0.1075, \"times_seen\": 108.0}, {\"site\": 212, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.1525995739454468, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07866702087848249, \"functional effect\": -0.0803, \"times_seen\": 18.0}, {\"site\": 212, \"mutant\": \"R\", \"log2 fold change IC90\": 0.10573152394603824, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.09409317278482485, \"functional effect\": -0.2016, \"times_seen\": 93.0}, {\"site\": 212, \"mutant\": \"S\", \"log2 fold change IC90\": -3.417248753875934, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.008185314585312442, \"functional effect\": -0.0871, \"times_seen\": 213.0}, {\"site\": 212, \"mutant\": \"T\", \"log2 fold change IC90\": 0.02428712692093346, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.08892848763481696, \"functional effect\": -0.1353, \"times_seen\": 135.0}, {\"site\": 212, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1765795048727577, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07737025446774004, \"functional effect\": -0.0999, \"times_seen\": 141.0}, {\"site\": 212, \"mutant\": \"W\", \"log2 fold change IC90\": -0.15775414576005822, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.07838645480767975, \"functional effect\": -0.2008, \"times_seen\": 12.0}, {\"site\": 212, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.11379536346467808, \"epitope\": \"all\", \"reference_site\": \"215\", \"IC90\": 0.0808116427129362, \"functional effect\": -0.0367, \"times_seen\": 271.0}, {\"site\": 213, \"mutant\": \"-\", \"log2 fold change IC90\": 0.009341227172326013, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08801197007015553, \"functional effect\": -1.3884, \"times_seen\": 4.0}, {\"site\": 213, \"mutant\": \"F\", \"log2 fold change IC90\": 0.18094965993509662, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.09912906917737366, \"functional effect\": 0.1345, \"times_seen\": 44.0}, {\"site\": 213, \"mutant\": \"I\", \"log2 fold change IC90\": 0.039264461076411336, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.0898565072388124, \"functional effect\": 0.0486, \"times_seen\": 14.0}, {\"site\": 213, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 213, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06721235021856758, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08346354355803197, \"functional effect\": 0.0678, \"times_seen\": 11.0}, {\"site\": 213, \"mutant\": \"P\", \"log2 fold change IC90\": -1.8292117480263608, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.02460833034886917, \"functional effect\": -0.8257, \"times_seen\": 85.0}, {\"site\": 213, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013689717237965792, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08661811679618868, \"functional effect\": -0.8349, \"times_seen\": 3.0}, {\"site\": 213, \"mutant\": \"R\", \"log2 fold change IC90\": -0.007011007837060967, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.0870200300973686, \"functional effect\": -0.7414, \"times_seen\": 2.0}, {\"site\": 213, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01475031876698173, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": 0.08655446263191706, \"functional effect\": -1.2806, \"times_seen\": 2.0}, {\"site\": 213, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"216\", \"IC90\": null, \"functional effect\": -0.3526, \"times_seen\": null}, {\"site\": 214, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 214, \"mutant\": \"H\", \"log2 fold change IC90\": -0.05299232889049618, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.0842902753003329, \"functional effect\": 0.1613, \"times_seen\": 14.0}, {\"site\": 214, \"mutant\": \"L\", \"log2 fold change IC90\": -0.050303964692819204, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08444749093684203, \"functional effect\": -0.0103, \"times_seen\": 7.0}, {\"site\": 214, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 214, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.017473924760408044, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.0885095083438119, \"functional effect\": 0.2183, \"times_seen\": 4.0}, {\"site\": 214, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02534412188543535, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08899366523850936, \"functional effect\": -0.003, \"times_seen\": 31.0}, {\"site\": 214, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0017061383494334705, \"epitope\": \"all\", \"reference_site\": \"217\", \"IC90\": 0.08734059657187246, \"functional effect\": -0.062, \"times_seen\": 6.0}, {\"site\": 215, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": null, \"functional effect\": -2.7657, \"times_seen\": null}, {\"site\": 215, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 215, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0127880029317017, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08667227183694677, \"functional effect\": 0.0077, \"times_seen\": 64.0}, {\"site\": 215, \"mutant\": \"H\", \"log2 fold change IC90\": -0.19421854709243408, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.07643005012972813, \"functional effect\": 0.0328, \"times_seen\": 124.0}, {\"site\": 215, \"mutant\": \"K\", \"log2 fold change IC90\": 0.08350808296209154, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.09265485711850617, \"functional effect\": -0.0633, \"times_seen\": 24.0}, {\"site\": 215, \"mutant\": \"L\", \"log2 fold change IC90\": 0.10458760132624391, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.0940185952444835, \"functional effect\": -0.1397, \"times_seen\": 85.0}, {\"site\": 215, \"mutant\": \"P\", \"log2 fold change IC90\": 0.01921764648372175, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08861655054965034, \"functional effect\": -0.1498, \"times_seen\": 11.0}, {\"site\": 215, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 215, \"mutant\": \"R\", \"log2 fold change IC90\": -0.010539556407536024, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08680745626666343, \"functional effect\": -0.1316, \"times_seen\": 92.0}, {\"site\": 215, \"mutant\": \"S\", \"log2 fold change IC90\": 0.013675769732087237, \"epitope\": \"all\", \"reference_site\": \"218\", \"IC90\": 0.08827679755261109, \"functional effect\": -0.1756, \"times_seen\": 7.0}, {\"site\": 216, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 216, \"mutant\": \"C\", \"log2 fold change IC90\": -0.017569924678300028, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.08638546562458665, \"functional effect\": -0.2669, \"times_seen\": 123.0}, {\"site\": 216, \"mutant\": \"D\", \"log2 fold change IC90\": 0.27005163868307136, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.10544437001755645, \"functional effect\": -0.1246, \"times_seen\": 136.0}, {\"site\": 216, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": null, \"functional effect\": 0.0321, \"times_seen\": null}, {\"site\": 216, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 216, \"mutant\": \"N\", \"log2 fold change IC90\": 0.02917517686569801, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.08923030062972603, \"functional effect\": -0.3667, \"times_seen\": 1.0}, {\"site\": 216, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0038161265822686157, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.0876755545312055, \"functional effect\": 0.0003, \"times_seen\": 1.0}, {\"site\": 216, \"mutant\": \"S\", \"log2 fold change IC90\": 0.3271096279677397, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.10969821547563813, \"functional effect\": -0.0416, \"times_seen\": 88.0}, {\"site\": 216, \"mutant\": \"V\", \"log2 fold change IC90\": -0.11111146012086531, \"epitope\": \"all\", \"reference_site\": \"219\", \"IC90\": 0.08096211977307377, \"functional effect\": -0.0095, \"times_seen\": 40.0}, {\"site\": 217, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 217, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": null, \"functional effect\": -1.2951, \"times_seen\": null}, {\"site\": 217, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 217, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01710720134677614, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.0884870126790313, \"functional effect\": 0.0326, \"times_seen\": 16.0}, {\"site\": 217, \"mutant\": \"L\", \"log2 fold change IC90\": 0.05860201674227963, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.09106903143701248, \"functional effect\": 0.003, \"times_seen\": 18.0}, {\"site\": 217, \"mutant\": \"S\", \"log2 fold change IC90\": 0.06947346057191292, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.091757875227556, \"functional effect\": -1.1228, \"times_seen\": 2.0}, {\"site\": 217, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01992300975258403, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.0862446828104479, \"functional effect\": 0.1777, \"times_seen\": 6.0}, {\"site\": 217, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0036347885217315923, \"epitope\": \"all\", \"reference_site\": \"220\", \"IC90\": 0.08722391431598372, \"functional effect\": -1.0107, \"times_seen\": 1.0}, {\"site\": 218, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 218, \"mutant\": \"A\", \"log2 fold change IC90\": -0.08174659110128833, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08262692238889746, \"functional effect\": 0.1215, \"times_seen\": 8.0}, {\"site\": 218, \"mutant\": \"C\", \"log2 fold change IC90\": -0.009882678816663697, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08684698981636856, \"functional effect\": -0.343, \"times_seen\": 1.0}, {\"site\": 218, \"mutant\": \"F\", \"log2 fold change IC90\": -0.011513546198271527, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08674887074463175, \"functional effect\": -0.326, \"times_seen\": 20.0}, {\"site\": 218, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03792969815646295, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08977341159798785, \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 218, \"mutant\": \"P\", \"log2 fold change IC90\": -0.056534191936894816, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08408359375352305, \"functional effect\": -1.9303, \"times_seen\": 18.0}, {\"site\": 218, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0488475179890215, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08453278642205853, \"functional effect\": 0.0561, \"times_seen\": 6.0}, {\"site\": 218, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 218, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06005896548745738, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08387841257311837, \"functional effect\": 0.0753, \"times_seen\": 12.0}, {\"site\": 218, \"mutant\": \"W\", \"log2 fold change IC90\": -0.007194151622795653, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08700898398868961, \"functional effect\": -0.2838, \"times_seen\": 5.0}, {\"site\": 218, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008443492865562017, \"epitope\": \"all\", \"reference_site\": \"221\", \"IC90\": 0.08693366879377398, \"functional effect\": -0.0299, \"times_seen\": 3.0}, {\"site\": 219, \"mutant\": \"*\", \"log2 fold change IC90\": -0.02519613042957073, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08593002967863426, \"functional effect\": -2.9784, \"times_seen\": 2.0}, {\"site\": 219, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 219, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 219, \"mutant\": \"C\", \"log2 fold change IC90\": -0.23048828683283248, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.07453253021802005, \"functional effect\": -0.0102, \"times_seen\": 35.0}, {\"site\": 219, \"mutant\": \"D\", \"log2 fold change IC90\": -0.06567821477570464, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08355234436547158, \"functional effect\": -0.4087, \"times_seen\": 43.0}, {\"site\": 219, \"mutant\": \"E\", \"log2 fold change IC90\": 0.21153305134000444, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.10125291762354012, \"functional effect\": -1.5791, \"times_seen\": 6.0}, {\"site\": 219, \"mutant\": \"F\", \"log2 fold change IC90\": 0.019716596031172623, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08864720348269078, \"functional effect\": -1.6507, \"times_seen\": 24.0}, {\"site\": 219, \"mutant\": \"G\", \"log2 fold change IC90\": -0.24831715715168776, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.07361712285113552, \"functional effect\": -0.2606, \"times_seen\": 66.0}, {\"site\": 219, \"mutant\": \"H\", \"log2 fold change IC90\": 0.002812701021499606, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.0876145954910038, \"functional effect\": -2.2013, \"times_seen\": 5.0}, {\"site\": 219, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03924793749526117, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.089855478093536, \"functional effect\": 0.1774, \"times_seen\": 43.0}, {\"site\": 219, \"mutant\": \"K\", \"log2 fold change IC90\": -0.047828683251273964, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08459250476503753, \"functional effect\": -3.1135, \"times_seen\": 1.0}, {\"site\": 219, \"mutant\": \"L\", \"log2 fold change IC90\": 0.2477300108454281, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.10382547266601311, \"functional effect\": -0.1977, \"times_seen\": 61.0}, {\"site\": 219, \"mutant\": \"M\", \"log2 fold change IC90\": -0.014728575267964707, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08655576714257392, \"functional effect\": -0.6407, \"times_seen\": 12.0}, {\"site\": 219, \"mutant\": \"N\", \"log2 fold change IC90\": -0.033437472419338754, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08544055694505878, \"functional effect\": -0.8643, \"times_seen\": 13.0}, {\"site\": 219, \"mutant\": \"P\", \"log2 fold change IC90\": 0.03632294642533609, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08967348521918564, \"functional effect\": -0.1476, \"times_seen\": 120.0}, {\"site\": 219, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.016844713624937713, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.0884709145842351, \"functional effect\": -0.4284, \"times_seen\": 10.0}, {\"site\": 219, \"mutant\": \"R\", \"log2 fold change IC90\": -0.012940339169510642, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08666312047065994, \"functional effect\": -1.8129, \"times_seen\": 13.0}, {\"site\": 219, \"mutant\": \"S\", \"log2 fold change IC90\": -0.7124862648653757, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.0533642015284161, \"functional effect\": -0.2461, \"times_seen\": 124.0}, {\"site\": 219, \"mutant\": \"T\", \"log2 fold change IC90\": 0.4495090977476434, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.1194113132389247, \"functional effect\": 0.0355, \"times_seen\": 139.0}, {\"site\": 219, \"mutant\": \"V\", \"log2 fold change IC90\": 0.023771526210019232, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08889671141202818, \"functional effect\": -0.1999, \"times_seen\": 102.0}, {\"site\": 219, \"mutant\": \"W\", \"log2 fold change IC90\": 0.013101378977483931, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.08824165825954415, \"functional effect\": -1.9779, \"times_seen\": 4.0}, {\"site\": 219, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.05782570003342847, \"epitope\": \"all\", \"reference_site\": \"222\", \"IC90\": 0.09102004021523465, \"functional effect\": -1.8799, \"times_seen\": 9.0}, {\"site\": 220, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -2.4924, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -2.5797, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0013202193689370743, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": 0.08736396318895995, \"functional effect\": -0.2449, \"times_seen\": 1.0}, {\"site\": 220, \"mutant\": \"S\", \"log2 fold change IC90\": 0.025319966664506723, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": 0.08899217521907474, \"functional effect\": -1.6638, \"times_seen\": 8.0}, {\"site\": 220, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -0.9401, \"times_seen\": null}, {\"site\": 220, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"223\", \"IC90\": null, \"functional effect\": -3.2667, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": null, \"functional effect\": -2.5387, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"A\", \"log2 fold change IC90\": 0.027139169409238016, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08910446293090447, \"functional effect\": -0.3753, \"times_seen\": 9.0}, {\"site\": 221, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"G\", \"log2 fold change IC90\": -0.007298531244502453, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08700268907809362, \"functional effect\": -1.0164, \"times_seen\": 8.0}, {\"site\": 221, \"mutant\": \"K\", \"log2 fold change IC90\": 0.007580345411122836, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08790461257095084, \"functional effect\": -0.878, \"times_seen\": 21.0}, {\"site\": 221, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03778862394516531, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08518325741660583, \"functional effect\": -1.3309, \"times_seen\": 6.0}, {\"site\": 221, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008981823614799683, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.08690123620375569, \"functional effect\": 0.0509, \"times_seen\": 5.0}, {\"site\": 221, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": null, \"functional effect\": -0.4872, \"times_seen\": null}, {\"site\": 221, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005153793466535212, \"epitope\": \"all\", \"reference_site\": \"224\", \"IC90\": 0.0871321251110331, \"functional effect\": -0.1249, \"times_seen\": 1.0}, {\"site\": 222, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 222, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": null, \"functional effect\": -2.138, \"times_seen\": null}, {\"site\": 222, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0024861274540866124, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08759476498489241, \"functional effect\": -2.1521, \"times_seen\": 13.0}, {\"site\": 222, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06939423344376669, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08333741151829216, \"functional effect\": -1.3977, \"times_seen\": 21.0}, {\"site\": 222, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 222, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.007838648405646615, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.086970123047976, \"functional effect\": -2.501, \"times_seen\": 1.0}, {\"site\": 222, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005595808799960232, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08710543351309134, \"functional effect\": -2.604, \"times_seen\": 1.0}, {\"site\": 222, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03346602506473796, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08543886599186677, \"functional effect\": -2.1988, \"times_seen\": 7.0}, {\"site\": 222, \"mutant\": \"V\", \"log2 fold change IC90\": -0.017404319156032185, \"epitope\": \"all\", \"reference_site\": \"225\", \"IC90\": 0.08639538229502469, \"functional effect\": -2.4981, \"times_seen\": 4.0}, {\"site\": 223, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": null, \"functional effect\": 0.0437, \"times_seen\": null}, {\"site\": 223, \"mutant\": \"F\", \"log2 fold change IC90\": 0.002999672270663574, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08762595095522135, \"functional effect\": -0.2731, \"times_seen\": 46.0}, {\"site\": 223, \"mutant\": \"I\", \"log2 fold change IC90\": 0.024449966939450445, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08893852574644172, \"functional effect\": 0.0083, \"times_seen\": 9.0}, {\"site\": 223, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 223, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0016732704818509042, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08754542540962533, \"functional effect\": -0.0651, \"times_seen\": 1.0}, {\"site\": 223, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0027342582132727426, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08727837648304049, \"functional effect\": -2.1574, \"times_seen\": 1.0}, {\"site\": 223, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009026619659755531, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08689853794034083, \"functional effect\": 0.0396, \"times_seen\": 2.0}, {\"site\": 223, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0008242086638703739, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.08739400481924811, \"functional effect\": -0.6241, \"times_seen\": 5.0}, {\"site\": 223, \"mutant\": \"V\", \"log2 fold change IC90\": 0.22529567995689723, \"epitope\": \"all\", \"reference_site\": \"226\", \"IC90\": 0.10222344441093606, \"functional effect\": -0.1381, \"times_seen\": 24.0}, {\"site\": 224, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": null, \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 224, \"mutant\": \"A\", \"log2 fold change IC90\": 0.060508762148599286, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.09118947286968308, \"functional effect\": -0.1855, \"times_seen\": 28.0}, {\"site\": 224, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": null, \"functional effect\": -0.0935, \"times_seen\": null}, {\"site\": 224, \"mutant\": \"G\", \"log2 fold change IC90\": -0.11892528409955427, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08052480375169174, \"functional effect\": -0.638, \"times_seen\": 9.0}, {\"site\": 224, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02788274608945087, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08915039992814426, \"functional effect\": -0.0408, \"times_seen\": 23.0}, {\"site\": 224, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02083269550340614, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.0887158093729027, \"functional effect\": -0.1253, \"times_seen\": 44.0}, {\"site\": 224, \"mutant\": \"M\", \"log2 fold change IC90\": 0.033637849263371794, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08950674305611364, \"functional effect\": -0.1129, \"times_seen\": 9.0}, {\"site\": 224, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": null, \"functional effect\": -3.0983, \"times_seen\": null}, {\"site\": 224, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00379868295580916, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.08721400598352672, \"functional effect\": -0.0495, \"times_seen\": 10.0}, {\"site\": 224, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"227\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 225, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05577522308703381, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.09089076693051737, \"functional effect\": -0.0925, \"times_seen\": 14.0}, {\"site\": 225, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 225, \"mutant\": \"E\", \"log2 fold change IC90\": 0.15937818404472381, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.0976578967929339, \"functional effect\": -0.023, \"times_seen\": 23.0}, {\"site\": 225, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07215035067800724, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08317835613083846, \"functional effect\": -0.3678, \"times_seen\": 57.0}, {\"site\": 225, \"mutant\": \"H\", \"log2 fold change IC90\": 1.1886330952613904, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.1993168285973406, \"functional effect\": -0.2091, \"times_seen\": 58.0}, {\"site\": 225, \"mutant\": \"N\", \"log2 fold change IC90\": -0.030676593809698158, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08560422068214062, \"functional effect\": 0.1782, \"times_seen\": 33.0}, {\"site\": 225, \"mutant\": \"R\", \"log2 fold change IC90\": -0.013377120114512317, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08663688688065782, \"functional effect\": -0.0463, \"times_seen\": 5.0}, {\"site\": 225, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03514667014436969, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08960040130233095, \"functional effect\": -0.3219, \"times_seen\": 13.0}, {\"site\": 225, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0069910360665168545, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08702123475674162, \"functional effect\": -0.3542, \"times_seen\": 2.0}, {\"site\": 225, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.022204208192099582, \"epitope\": \"all\", \"reference_site\": \"228\", \"IC90\": 0.08610841993576916, \"functional effect\": -0.0169, \"times_seen\": 56.0}, {\"site\": 226, \"mutant\": \"F\", \"log2 fold change IC90\": 0.03574150533333979, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08963735191152811, \"functional effect\": -0.4365, \"times_seen\": 19.0}, {\"site\": 226, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 226, \"mutant\": \"M\", \"log2 fold change IC90\": 6.001510611106942e-05, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08744758477907436, \"functional effect\": -0.1964, \"times_seen\": 10.0}, {\"site\": 226, \"mutant\": \"P\", \"log2 fold change IC90\": 0.011785870925959075, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08816123259764784, \"functional effect\": -1.6609, \"times_seen\": 10.0}, {\"site\": 226, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": null, \"functional effect\": 0.0504, \"times_seen\": null}, {\"site\": 226, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": null, \"functional effect\": -1.7349, \"times_seen\": null}, {\"site\": 226, \"mutant\": \"S\", \"log2 fold change IC90\": 0.044919131816599164, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.09020939265223207, \"functional effect\": -0.715, \"times_seen\": 5.0}, {\"site\": 226, \"mutant\": \"V\", \"log2 fold change IC90\": 0.026502006946028882, \"epitope\": \"all\", \"reference_site\": \"229\", \"IC90\": 0.08906511886838764, \"functional effect\": 0.1363, \"times_seen\": 1.0}, {\"site\": 227, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04085049356868749, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.085002662457847, \"functional effect\": 0.2964, \"times_seen\": 9.0}, {\"site\": 227, \"mutant\": \"G\", \"log2 fold change IC90\": 0.004909986199925156, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08774205584492238, \"functional effect\": -0.0536, \"times_seen\": 2.0}, {\"site\": 227, \"mutant\": \"L\", \"log2 fold change IC90\": 0.04394585124115758, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.09014855551203887, \"functional effect\": -1.4392, \"times_seen\": 31.0}, {\"site\": 227, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 227, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01244207198549064, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08669305669797187, \"functional effect\": -0.6773, \"times_seen\": 7.0}, {\"site\": 227, \"mutant\": \"S\", \"log2 fold change IC90\": 0.008270626381551, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.0879466820300299, \"functional effect\": 0.3933, \"times_seen\": 14.0}, {\"site\": 227, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05548925115213471, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08414451737278833, \"functional effect\": -0.1116, \"times_seen\": 19.0}, {\"site\": 227, \"mutant\": \"V\", \"log2 fold change IC90\": 0.01261033030921958, \"epitope\": \"all\", \"reference_site\": \"230\", \"IC90\": 0.08821162864543539, \"functional effect\": -0.2995, \"times_seen\": 4.0}, {\"site\": 228, \"mutant\": \"F\", \"log2 fold change IC90\": -0.013525937309100022, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.08662795055445092, \"functional effect\": -0.6077, \"times_seen\": 2.0}, {\"site\": 228, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 228, \"mutant\": \"L\", \"log2 fold change IC90\": 0.6825655631360125, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.1403467826958648, \"functional effect\": -0.7924, \"times_seen\": 7.0}, {\"site\": 228, \"mutant\": \"M\", \"log2 fold change IC90\": -1.684620176995035, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.027202483042873656, \"functional effect\": -0.3036, \"times_seen\": 17.0}, {\"site\": 228, \"mutant\": \"N\", \"log2 fold change IC90\": 0.008791178378178359, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.08797842060257753, \"functional effect\": -1.1128, \"times_seen\": 5.0}, {\"site\": 228, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": null, \"functional effect\": -0.0682, \"times_seen\": null}, {\"site\": 228, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05256872522065632, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.08431502821858232, \"functional effect\": 0.1064, \"times_seen\": 24.0}, {\"site\": 228, \"mutant\": \"V\", \"log2 fold change IC90\": 0.07174555918286313, \"epitope\": \"all\", \"reference_site\": \"231\", \"IC90\": 0.09190249844376827, \"functional effect\": 0.2946, \"times_seen\": 7.0}, {\"site\": 229, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00014471527960447758, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.0874351761223522, \"functional effect\": -0.0781, \"times_seen\": 19.0}, {\"site\": 229, \"mutant\": \"C\", \"log2 fold change IC90\": -0.20536007352256813, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.07584207573631824, \"functional effect\": -0.0445, \"times_seen\": 60.0}, {\"site\": 229, \"mutant\": \"D\", \"log2 fold change IC90\": -0.8477766547117218, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.04858738773086693, \"functional effect\": -0.2295, \"times_seen\": 42.0}, {\"site\": 229, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 229, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 229, \"mutant\": \"K\", \"log2 fold change IC90\": -0.018906222244007585, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.08630548805552896, \"functional effect\": -1.2574, \"times_seen\": 6.0}, {\"site\": 229, \"mutant\": \"R\", \"log2 fold change IC90\": -0.038852974977736654, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.08512043648110251, \"functional effect\": -0.8465, \"times_seen\": 16.0}, {\"site\": 229, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03623467210126793, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.08966799852664098, \"functional effect\": 0.1679, \"times_seen\": 35.0}, {\"site\": 229, \"mutant\": \"V\", \"log2 fold change IC90\": -0.12769752765001172, \"epitope\": \"all\", \"reference_site\": \"232\", \"IC90\": 0.08003666180165529, \"functional effect\": 0.1446, \"times_seen\": 31.0}, {\"site\": 230, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 230, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0024443401641641217, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.08759222786185089, \"functional effect\": 0.1623, \"times_seen\": 2.0}, {\"site\": 230, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": null, \"functional effect\": -0.229, \"times_seen\": null}, {\"site\": 230, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": null, \"functional effect\": 0.0646, \"times_seen\": null}, {\"site\": 230, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0037251961666487695, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.0872184485305105, \"functional effect\": -0.4334, \"times_seen\": 7.0}, {\"site\": 230, \"mutant\": \"T\", \"log2 fold change IC90\": -1.329248415367059, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.034800550029447604, \"functional effect\": -0.4892, \"times_seen\": 12.0}, {\"site\": 230, \"mutant\": \"V\", \"log2 fold change IC90\": 0.012576011774958247, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.08820953031023072, \"functional effect\": 0.0266, \"times_seen\": 10.0}, {\"site\": 230, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.023508479273520788, \"epitope\": \"all\", \"reference_site\": \"233\", \"IC90\": 0.08603060863979177, \"functional effect\": -1.2702, \"times_seen\": 6.0}, {\"site\": 231, \"mutant\": \"-\", \"log2 fold change IC90\": -0.003963176650713552, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08720406255414365, \"functional effect\": -3.2703, \"times_seen\": 1.0}, {\"site\": 231, \"mutant\": \"D\", \"log2 fold change IC90\": -0.011555343424588683, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08674635752488853, \"functional effect\": 0.1887, \"times_seen\": 15.0}, {\"site\": 231, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06030765948716868, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08386395472895875, \"functional effect\": 0.2882, \"times_seen\": 10.0}, {\"site\": 231, \"mutant\": \"K\", \"log2 fold change IC90\": -0.976736359522436, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.04443271088023354, \"functional effect\": 0.0597, \"times_seen\": 27.0}, {\"site\": 231, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 231, \"mutant\": \"P\", \"log2 fold change IC90\": -0.02410084845289721, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08599529180665685, \"functional effect\": 0.4295, \"times_seen\": 9.0}, {\"site\": 231, \"mutant\": \"S\", \"log2 fold change IC90\": -0.041552416040569924, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08496131569711696, \"functional effect\": -0.0906, \"times_seen\": 2.0}, {\"site\": 231, \"mutant\": \"T\", \"log2 fold change IC90\": -0.044968290597482016, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08476039042516838, \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 231, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.09073372239609838, \"epitope\": \"all\", \"reference_site\": \"234\", \"IC90\": 0.08211380571373711, \"functional effect\": 0.2545, \"times_seen\": 23.0}, {\"site\": 232, \"mutant\": \"-\", \"log2 fold change IC90\": 0.0007349352186357844, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08748850398903085, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 232, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02110726195344834, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08873269492541469, \"functional effect\": -0.9604, \"times_seen\": 2.0}, {\"site\": 232, \"mutant\": \"F\", \"log2 fold change IC90\": 0.049341227232630326, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.09048632334414909, \"functional effect\": -0.5704, \"times_seen\": 15.0}, {\"site\": 232, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 232, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010066972493803788, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08683589646094082, \"functional effect\": -0.2026, \"times_seen\": 3.0}, {\"site\": 232, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": null, \"functional effect\": -2.8017, \"times_seen\": null}, {\"site\": 232, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02261819978094367, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.08608371405800949, \"functional effect\": -1.1048, \"times_seen\": 7.0}, {\"site\": 232, \"mutant\": \"T\", \"log2 fold change IC90\": 0.13110676772159363, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.09576279705865491, \"functional effect\": -1.0273, \"times_seen\": 10.0}, {\"site\": 232, \"mutant\": \"V\", \"log2 fold change IC90\": 0.014847792774305783, \"epitope\": \"all\", \"reference_site\": \"235\", \"IC90\": 0.0883485413896064, \"functional effect\": -0.665, \"times_seen\": 3.0}, {\"site\": 233, \"mutant\": \"-\", \"log2 fold change IC90\": 0.00023300715825435645, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08745807115611796, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 233, \"mutant\": \"A\", \"log2 fold change IC90\": 0.022554224776970163, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08882173475368033, \"functional effect\": 0.0943, \"times_seen\": 2.0}, {\"site\": 233, \"mutant\": \"I\", \"log2 fold change IC90\": 0.05584802651411162, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.09089535371157645, \"functional effect\": -0.123, \"times_seen\": 4.0}, {\"site\": 233, \"mutant\": \"L\", \"log2 fold change IC90\": 0.003315293796610558, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.0876451231718305, \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 233, \"mutant\": \"N\", \"log2 fold change IC90\": 0.015446953815415613, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08838524075863036, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 233, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01641657464207118, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08645455334786736, \"functional effect\": -0.1354, \"times_seen\": 4.0}, {\"site\": 233, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 233, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03491986974190951, \"epitope\": \"all\", \"reference_site\": \"236\", \"IC90\": 0.08535281019307489, \"functional effect\": 0.3651, \"times_seen\": 8.0}, {\"site\": 234, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": null, \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 234, \"mutant\": \"C\", \"log2 fold change IC90\": 0.02180647796239976, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08877571050142023, \"functional effect\": -0.1122, \"times_seen\": 16.0}, {\"site\": 234, \"mutant\": \"G\", \"log2 fold change IC90\": 0.008456491948559571, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08795801312389673, \"functional effect\": -0.0881, \"times_seen\": 35.0}, {\"site\": 234, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0578943916910734, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.09102437409461565, \"functional effect\": -0.0887, \"times_seen\": 56.0}, {\"site\": 234, \"mutant\": \"M\", \"log2 fold change IC90\": -0.13370159530452305, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.07970426516852519, \"functional effect\": -0.1069, \"times_seen\": 60.0}, {\"site\": 234, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 234, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07420151453633213, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08306018062896177, \"functional effect\": 0.0239, \"times_seen\": 59.0}, {\"site\": 234, \"mutant\": \"W\", \"log2 fold change IC90\": -0.008854177857063213, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08690892533039994, \"functional effect\": 0.1662, \"times_seen\": 2.0}, {\"site\": 234, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03468346161427514, \"epitope\": \"all\", \"reference_site\": \"237\", \"IC90\": 0.08536679773085161, \"functional effect\": -0.2899, \"times_seen\": 17.0}, {\"site\": 235, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": null, \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 235, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": null, \"functional effect\": 0.0113, \"times_seen\": null}, {\"site\": 235, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 235, \"mutant\": \"I\", \"log2 fold change IC90\": 0.08533040991505628, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.092771967195565, \"functional effect\": -0.1208, \"times_seen\": 15.0}, {\"site\": 235, \"mutant\": \"L\", \"log2 fold change IC90\": 0.014424064534416406, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.08832259670007668, \"functional effect\": -0.2954, \"times_seen\": 13.0}, {\"site\": 235, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00249285695655101, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": 0.08729298169895933, \"functional effect\": -2.7351, \"times_seen\": 1.0}, {\"site\": 235, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"238\", \"IC90\": null, \"functional effect\": -0.1558, \"times_seen\": null}, {\"site\": 236, \"mutant\": \"*\", \"log2 fold change IC90\": 0.1557174773859597, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.09741041293219004, \"functional effect\": -3.0623, \"times_seen\": 1.0}, {\"site\": 236, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01668427313559624, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08643851280849264, \"functional effect\": -0.0871, \"times_seen\": 6.0}, {\"site\": 236, \"mutant\": \"H\", \"log2 fold change IC90\": 0.012952827669454903, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08823257266727709, \"functional effect\": -0.1024, \"times_seen\": 20.0}, {\"site\": 236, \"mutant\": \"K\", \"log2 fold change IC90\": -0.022188432444773972, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08610936152915111, \"functional effect\": 0.0548, \"times_seen\": 14.0}, {\"site\": 236, \"mutant\": \"L\", \"log2 fold change IC90\": -0.036221523606034894, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08527583639895836, \"functional effect\": -0.0449, \"times_seen\": 21.0}, {\"site\": 236, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": null, \"functional effect\": -2.1075, \"times_seen\": null}, {\"site\": 236, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 236, \"mutant\": \"R\", \"log2 fold change IC90\": -0.17995725736230697, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.07718932095878424, \"functional effect\": -0.018, \"times_seen\": 77.0}, {\"site\": 236, \"mutant\": \"T\", \"log2 fold change IC90\": -0.005628589756147959, \"epitope\": \"all\", \"reference_site\": \"239\", \"IC90\": 0.08710345432353375, \"functional effect\": 0.1525, \"times_seen\": 2.0}, {\"site\": 237, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03809554129724298, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08516513755182659, \"functional effect\": -0.0885, \"times_seen\": 13.0}, {\"site\": 237, \"mutant\": \"I\", \"log2 fold change IC90\": -0.08744308408434187, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08230131258019097, \"functional effect\": -0.0874, \"times_seen\": 49.0}, {\"site\": 237, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01061833558164962, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08808991488077313, \"functional effect\": -0.169, \"times_seen\": 2.0}, {\"site\": 237, \"mutant\": \"N\", \"log2 fold change IC90\": -0.031037197102362673, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08558282648211983, \"functional effect\": -0.4746, \"times_seen\": 8.0}, {\"site\": 237, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0015034536378095676, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08735286794365102, \"functional effect\": -0.0441, \"times_seen\": 5.0}, {\"site\": 237, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 237, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004518612129737217, \"epitope\": \"all\", \"reference_site\": \"240\", \"IC90\": 0.08717049557973629, \"functional effect\": -0.0511, \"times_seen\": 10.0}, {\"site\": 238, \"mutant\": \"-\", \"log2 fold change IC90\": -0.032269428812531024, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08550975986323037, \"functional effect\": -0.0169, \"times_seen\": 26.0}, {\"site\": 238, \"mutant\": \"F\", \"log2 fold change IC90\": -0.00819867985809863, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08694842194543434, \"functional effect\": -0.4513, \"times_seen\": 7.0}, {\"site\": 238, \"mutant\": \"I\", \"log2 fold change IC90\": 0.013097892598036351, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08824144501729728, \"functional effect\": -0.0413, \"times_seen\": 2.0}, {\"site\": 238, \"mutant\": \"K\", \"log2 fold change IC90\": -0.020723654295992728, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.0861968333510974, \"functional effect\": -0.1915, \"times_seen\": 2.0}, {\"site\": 238, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 238, \"mutant\": \"M\", \"log2 fold change IC90\": -0.005221839279658625, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08712801555474146, \"functional effect\": -0.4464, \"times_seen\": 8.0}, {\"site\": 238, \"mutant\": \"P\", \"log2 fold change IC90\": -0.006060016994351418, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08707741057665656, \"functional effect\": -1.983, \"times_seen\": 2.0}, {\"site\": 238, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": null, \"functional effect\": -0.0438, \"times_seen\": null}, {\"site\": 238, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00508121459369178, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08713650865039839, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 238, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03193444661790231, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08940112402712841, \"functional effect\": 0.077, \"times_seen\": 15.0}, {\"site\": 238, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012295338387473572, \"epitope\": \"all\", \"reference_site\": \"241\", \"IC90\": 0.08670187452204167, \"functional effect\": -0.453, \"times_seen\": 5.0}, {\"site\": 239, \"mutant\": \"-\", \"log2 fold change IC90\": -0.02549445450364124, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08591226269007417, \"functional effect\": -0.0762, \"times_seen\": 14.0}, {\"site\": 239, \"mutant\": \"F\", \"log2 fold change IC90\": 0.007531114443486095, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08790161293819679, \"functional effect\": 0.1729, \"times_seen\": 13.0}, {\"site\": 239, \"mutant\": \"H\", \"log2 fold change IC90\": 0.017396773281917324, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08850477521820307, \"functional effect\": -0.3791, \"times_seen\": 8.0}, {\"site\": 239, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0069540172843567515, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08702346770367203, \"functional effect\": -0.1038, \"times_seen\": 7.0}, {\"site\": 239, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 239, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013827352930653316, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08660985366676295, \"functional effect\": 0.1964, \"times_seen\": 3.0}, {\"site\": 239, \"mutant\": \"P\", \"log2 fold change IC90\": 0.01960535714909721, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08864036861088598, \"functional effect\": -0.1182, \"times_seen\": 9.0}, {\"site\": 239, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.08035273718323253, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.09245243136255515, \"functional effect\": -0.1558, \"times_seen\": 6.0}, {\"site\": 239, \"mutant\": \"R\", \"log2 fold change IC90\": 0.010669884158718213, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08809306245580703, \"functional effect\": -0.0741, \"times_seen\": 5.0}, {\"site\": 239, \"mutant\": \"V\", \"log2 fold change IC90\": -0.019274802438206663, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08628344151796215, \"functional effect\": -0.0102, \"times_seen\": 4.0}, {\"site\": 239, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0017036686899896372, \"epitope\": \"all\", \"reference_site\": \"242\", \"IC90\": 0.08754727004901519, \"functional effect\": 0.0411, \"times_seen\": 3.0}, {\"site\": 240, \"mutant\": \"-\", \"log2 fold change IC90\": -0.023145261022553328, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.0860522707514551, \"functional effect\": 0.0648, \"times_seen\": 23.0}, {\"site\": 240, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 240, \"mutant\": \"D\", \"log2 fold change IC90\": 0.02351836844808207, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08888111357779939, \"functional effect\": -0.003, \"times_seen\": 27.0}, {\"site\": 240, \"mutant\": \"F\", \"log2 fold change IC90\": -0.047034595902989335, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08463907893779998, \"functional effect\": -0.5302, \"times_seen\": 13.0}, {\"site\": 240, \"mutant\": \"G\", \"log2 fold change IC90\": 2.057423197127216, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.3639785989381115, \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 240, \"mutant\": \"L\", \"log2 fold change IC90\": 6.382913405462674e-05, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08744781596304833, \"functional effect\": 0.1752, \"times_seen\": 4.0}, {\"site\": 240, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": null, \"functional effect\": 0.0181, \"times_seen\": null}, {\"site\": 240, \"mutant\": \"P\", \"log2 fold change IC90\": 0.08677803057116228, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.09286510262150126, \"functional effect\": -0.1026, \"times_seen\": 14.0}, {\"site\": 240, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05838705731976136, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08397567380249493, \"functional effect\": 0.0128, \"times_seen\": 56.0}, {\"site\": 240, \"mutant\": \"T\", \"log2 fold change IC90\": -0.48026698540341994, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.06268375208310754, \"functional effect\": -0.0384, \"times_seen\": 93.0}, {\"site\": 240, \"mutant\": \"V\", \"log2 fold change IC90\": -0.06634406757849687, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08351379101588353, \"functional effect\": -0.0605, \"times_seen\": 48.0}, {\"site\": 240, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012064488841748997, \"epitope\": \"all\", \"reference_site\": \"243\", \"IC90\": 0.08671574903411752, \"functional effect\": -0.0469, \"times_seen\": 12.0}, {\"site\": 241, \"mutant\": \"-\", \"log2 fold change IC90\": -0.020149334814553558, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08623115410088324, \"functional effect\": 0.0433, \"times_seen\": 14.0}, {\"site\": 241, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010147900794171365, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08683102551856428, \"functional effect\": 0.1124, \"times_seen\": 2.0}, {\"site\": 241, \"mutant\": \"F\", \"log2 fold change IC90\": -0.022346999358657398, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08609989775129617, \"functional effect\": -0.1492, \"times_seen\": 9.0}, {\"site\": 241, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01225158561985343, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.086704503978984, \"functional effect\": -0.0313, \"times_seen\": 6.0}, {\"site\": 241, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 241, \"mutant\": \"M\", \"log2 fold change IC90\": -1.7679414028537936, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.02567594046363963, \"functional effect\": 0.0693, \"times_seen\": 8.0}, {\"site\": 241, \"mutant\": \"P\", \"log2 fold change IC90\": -0.001776980509209096, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.0873363079007318, \"functional effect\": 0.1182, \"times_seen\": 23.0}, {\"site\": 241, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016270350160636913, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.086463316400729, \"functional effect\": -0.3063, \"times_seen\": 1.0}, {\"site\": 241, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": null, \"functional effect\": 0.1266, \"times_seen\": null}, {\"site\": 241, \"mutant\": \"S\", \"log2 fold change IC90\": -0.030994747990510142, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08558534466393793, \"functional effect\": -0.2637, \"times_seen\": 10.0}, {\"site\": 241, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0055216030434193635, \"epitope\": \"all\", \"reference_site\": \"244\", \"IC90\": 0.08710991394079422, \"functional effect\": 0.1729, \"times_seen\": 9.0}, {\"site\": 242, \"mutant\": \"-\", \"log2 fold change IC90\": 0.08992826659053048, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.09306810229572005, \"functional effect\": 0.1197, \"times_seen\": 15.0}, {\"site\": 242, \"mutant\": \"D\", \"log2 fold change IC90\": -0.00645714721128313, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08705344410359847, \"functional effect\": -0.1089, \"times_seen\": 5.0}, {\"site\": 242, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 242, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02511565071487309, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08897957294844808, \"functional effect\": -0.628, \"times_seen\": 12.0}, {\"site\": 242, \"mutant\": \"N\", \"log2 fold change IC90\": 0.04874788452176407, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.09044911633930136, \"functional effect\": -0.0195, \"times_seen\": 11.0}, {\"site\": 242, \"mutant\": \"P\", \"log2 fold change IC90\": 0.004222810937588711, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08770027306245776, \"functional effect\": -0.0842, \"times_seen\": 13.0}, {\"site\": 242, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01631884455797101, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08646041009285983, \"functional effect\": 0.1609, \"times_seen\": 2.0}, {\"site\": 242, \"mutant\": \"R\", \"log2 fold change IC90\": -0.025000179403150257, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08594170173723893, \"functional effect\": -0.0004, \"times_seen\": 17.0}, {\"site\": 242, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03659612481015639, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.08525369708108088, \"functional effect\": -0.1595, \"times_seen\": 6.0}, {\"site\": 242, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.13452412447694892, \"epitope\": \"all\", \"reference_site\": \"245\", \"IC90\": 0.07965883602637273, \"functional effect\": -0.022, \"times_seen\": 66.0}, {\"site\": 243, \"mutant\": \"-\", \"log2 fold change IC90\": 0.031566917860351346, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08937835185545347, \"functional effect\": 0.0957, \"times_seen\": 8.0}, {\"site\": 243, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": null, \"functional effect\": 0.0263, \"times_seen\": null}, {\"site\": 243, \"mutant\": \"E\", \"log2 fold change IC90\": -0.012786062470632745, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08667238841340791, \"functional effect\": 0.0858, \"times_seen\": 12.0}, {\"site\": 243, \"mutant\": \"G\", \"log2 fold change IC90\": 0.1954571072849258, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.10013091965723106, \"functional effect\": 0.1092, \"times_seen\": 62.0}, {\"site\": 243, \"mutant\": \"I\", \"log2 fold change IC90\": -0.002414517898457361, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08729772187996754, \"functional effect\": -0.0162, \"times_seen\": 42.0}, {\"site\": 243, \"mutant\": \"K\", \"log2 fold change IC90\": 0.04665115156327369, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.09031775808757186, \"functional effect\": -0.0306, \"times_seen\": 46.0}, {\"site\": 243, \"mutant\": \"M\", \"log2 fold change IC90\": -0.008794327150770678, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08691253085222714, \"functional effect\": 0.169, \"times_seen\": 9.0}, {\"site\": 243, \"mutant\": \"N\", \"log2 fold change IC90\": 0.008637038691835856, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08796902135924393, \"functional effect\": 0.1541, \"times_seen\": 7.0}, {\"site\": 243, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 243, \"mutant\": \"S\", \"log2 fold change IC90\": 0.9683440407960506, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.17109225691921434, \"functional effect\": 0.0437, \"times_seen\": 57.0}, {\"site\": 243, \"mutant\": \"T\", \"log2 fold change IC90\": -0.12367949170026678, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08025988183095943, \"functional effect\": -0.0659, \"times_seen\": 25.0}, {\"site\": 243, \"mutant\": \"W\", \"log2 fold change IC90\": 0.015450216578797983, \"epitope\": \"all\", \"reference_site\": \"246\", \"IC90\": 0.08838544064872841, \"functional effect\": 0.0583, \"times_seen\": 29.0}, {\"site\": 244, \"mutant\": \"-\", \"log2 fold change IC90\": 0.09986067269503444, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.09371105143833246, \"functional effect\": -0.0932, \"times_seen\": 11.0}, {\"site\": 244, \"mutant\": \"C\", \"log2 fold change IC90\": 0.026788289536194207, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08908279434532994, \"functional effect\": 0.0591, \"times_seen\": 7.0}, {\"site\": 244, \"mutant\": \"F\", \"log2 fold change IC90\": 0.024317171934454346, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08893033964467309, \"functional effect\": 0.2911, \"times_seen\": 2.0}, {\"site\": 244, \"mutant\": \"G\", \"log2 fold change IC90\": 0.7196916556070418, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.14400531742135392, \"functional effect\": -0.0707, \"times_seen\": 20.0}, {\"site\": 244, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06786638306539546, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08342571468508557, \"functional effect\": -0.0197, \"times_seen\": 36.0}, {\"site\": 244, \"mutant\": \"N\", \"log2 fold change IC90\": -0.044647400073916994, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08477924529771799, \"functional effect\": -0.0213, \"times_seen\": 32.0}, {\"site\": 244, \"mutant\": \"P\", \"log2 fold change IC90\": 0.019959878644268698, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08866215337935605, \"functional effect\": -0.0426, \"times_seen\": 11.0}, {\"site\": 244, \"mutant\": \"R\", \"log2 fold change IC90\": -0.04720078130706607, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08462932984388809, \"functional effect\": -0.0617, \"times_seen\": 8.0}, {\"site\": 244, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 244, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006158851537701666, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08707144537882931, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 244, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0006833080144453928, \"epitope\": \"all\", \"reference_site\": \"247\", \"IC90\": 0.08748537324697137, \"functional effect\": 0.0067, \"times_seen\": 2.0}, {\"site\": 245, \"mutant\": \"*\", \"log2 fold change IC90\": -0.008502228861956309, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08693012956228621, \"functional effect\": -1.6307, \"times_seen\": 2.0}, {\"site\": 245, \"mutant\": \"-\", \"log2 fold change IC90\": 0.09694285625271375, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.09352171459251166, \"functional effect\": 0.0923, \"times_seen\": 14.0}, {\"site\": 245, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0650864530560776, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08358662272589869, \"functional effect\": -0.1126, \"times_seen\": 48.0}, {\"site\": 245, \"mutant\": \"F\", \"log2 fold change IC90\": 0.002042661391219594, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08756784360872442, \"functional effect\": -0.12, \"times_seen\": 17.0}, {\"site\": 245, \"mutant\": \"H\", \"log2 fold change IC90\": -0.09107660189928839, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08209429237611826, \"functional effect\": 0.0527, \"times_seen\": 61.0}, {\"site\": 245, \"mutant\": \"L\", \"log2 fold change IC90\": 0.014231808080486394, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08831082743673366, \"functional effect\": -0.3252, \"times_seen\": 4.0}, {\"site\": 245, \"mutant\": \"N\", \"log2 fold change IC90\": 0.009187574850711745, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.08800259697117349, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 245, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": null, \"functional effect\": -0.3224, \"times_seen\": null}, {\"site\": 245, \"mutant\": \"S\", \"log2 fold change IC90\": 0.13386214810997005, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.09594586767286827, \"functional effect\": -0.0493, \"times_seen\": 17.0}, {\"site\": 245, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"248\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 246, \"mutant\": \"-\", \"log2 fold change IC90\": 0.019091920996050733, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08860882828453678, \"functional effect\": 0.0026, \"times_seen\": 12.0}, {\"site\": 246, \"mutant\": \"F\", \"log2 fold change IC90\": -0.10264351218280601, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08143872707020297, \"functional effect\": 0.0119, \"times_seen\": 23.0}, {\"site\": 246, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 246, \"mutant\": \"M\", \"log2 fold change IC90\": 0.08830672966117928, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.09296355588658138, \"functional effect\": -0.0304, \"times_seen\": 15.0}, {\"site\": 246, \"mutant\": \"P\", \"log2 fold change IC90\": 0.012479083870833027, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.0882036041252471, \"functional effect\": 0.054, \"times_seen\": 34.0}, {\"site\": 246, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013773190313970418, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08661310529252576, \"functional effect\": -0.1483, \"times_seen\": 2.0}, {\"site\": 246, \"mutant\": \"R\", \"log2 fold change IC90\": -0.5089091782536601, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.06145154766202577, \"functional effect\": 0.0215, \"times_seen\": 3.0}, {\"site\": 246, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05686922259263979, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.0840640696614294, \"functional effect\": 0.0081, \"times_seen\": 15.0}, {\"site\": 246, \"mutant\": \"V\", \"log2 fold change IC90\": -0.019002031703614527, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08629975669347739, \"functional effect\": -0.042, \"times_seen\": 5.0}, {\"site\": 246, \"mutant\": \"W\", \"log2 fold change IC90\": 0.012639750430539509, \"epitope\": \"all\", \"reference_site\": \"249\", \"IC90\": 0.08821342751713346, \"functional effect\": 0.1009, \"times_seen\": 4.0}, {\"site\": 247, \"mutant\": \"-\", \"log2 fold change IC90\": 0.03817690577857925, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08978879570374905, \"functional effect\": 0.0723, \"times_seen\": 38.0}, {\"site\": 247, \"mutant\": \"A\", \"log2 fold change IC90\": 0.7242747810223107, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.1444635181160001, \"functional effect\": -0.0908, \"times_seen\": 31.0}, {\"site\": 247, \"mutant\": \"F\", \"log2 fold change IC90\": -0.02613458503427881, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.0858741514733811, \"functional effect\": -0.2072, \"times_seen\": 6.0}, {\"site\": 247, \"mutant\": \"I\", \"log2 fold change IC90\": -0.10638473557561096, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08122781225319294, \"functional effect\": -0.0007, \"times_seen\": 63.0}, {\"site\": 247, \"mutant\": \"K\", \"log2 fold change IC90\": 0.009795506041038004, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08803968782930002, \"functional effect\": 0.3528, \"times_seen\": 6.0}, {\"site\": 247, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03015545231648778, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08929095100583803, \"functional effect\": 0.0803, \"times_seen\": 5.0}, {\"site\": 247, \"mutant\": \"N\", \"log2 fold change IC90\": 0.07981125895740349, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.09241773824743488, \"functional effect\": 0.0791, \"times_seen\": 48.0}, {\"site\": 247, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0053307635612211595, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.0877676504815203, \"functional effect\": 0.0563, \"times_seen\": 12.0}, {\"site\": 247, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014592094394764738, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08656395582080144, \"functional effect\": 0.0533, \"times_seen\": 7.0}, {\"site\": 247, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004392536207988856, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08717811366983146, \"functional effect\": -0.5234, \"times_seen\": 2.0}, {\"site\": 247, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02280137736141907, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.08607278478675487, \"functional effect\": 0.3226, \"times_seen\": 11.0}, {\"site\": 247, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"250\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 248, \"mutant\": \"-\", \"log2 fold change IC90\": 0.00015673324417454716, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08745344745333923, \"functional effect\": -0.0369, \"times_seen\": 23.0}, {\"site\": 248, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 248, \"mutant\": \"H\", \"log2 fold change IC90\": -0.2447208816412534, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.07380086071483755, \"functional effect\": -0.0713, \"times_seen\": 45.0}, {\"site\": 248, \"mutant\": \"L\", \"log2 fold change IC90\": -0.029671195719638648, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.0856638981010211, \"functional effect\": -0.0358, \"times_seen\": 27.0}, {\"site\": 248, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 248, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01672547494887844, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08643604425310882, \"functional effect\": -0.4598, \"times_seen\": 4.0}, {\"site\": 248, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03928319403705144, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08985767400607376, \"functional effect\": -0.0942, \"times_seen\": 18.0}, {\"site\": 248, \"mutant\": \"T\", \"log2 fold change IC90\": 0.8624696044473651, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.15898603340091202, \"functional effect\": -0.0788, \"times_seen\": 39.0}, {\"site\": 248, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004686642187484715, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08716034346162124, \"functional effect\": -0.1832, \"times_seen\": 2.0}, {\"site\": 248, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02394616108563232, \"epitope\": \"all\", \"reference_site\": \"251\", \"IC90\": 0.08600451281184747, \"functional effect\": 0.2736, \"times_seen\": 11.0}, {\"site\": 249, \"mutant\": \"*\", \"log2 fold change IC90\": 0.029028947044163055, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08922125681289865, \"functional effect\": -2.368, \"times_seen\": 1.0}, {\"site\": 249, \"mutant\": \"-\", \"log2 fold change IC90\": -0.005276060400229732, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08712474106517241, \"functional effect\": 0.0209, \"times_seen\": 25.0}, {\"site\": 249, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": null, \"functional effect\": -0.3516, \"times_seen\": null}, {\"site\": 249, \"mutant\": \"D\", \"log2 fold change IC90\": -0.08045478194015127, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08270094081550738, \"functional effect\": -0.0529, \"times_seen\": 37.0}, {\"site\": 249, \"mutant\": \"E\", \"log2 fold change IC90\": -0.019997044782207755, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08624025709078072, \"functional effect\": 0.2515, \"times_seen\": 11.0}, {\"site\": 249, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 249, \"mutant\": \"I\", \"log2 fold change IC90\": 1.2494370175251532, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.2078967847673069, \"functional effect\": -0.3223, \"times_seen\": 10.0}, {\"site\": 249, \"mutant\": \"L\", \"log2 fold change IC90\": -0.017389440686069305, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08639627329256215, \"functional effect\": 0.1264, \"times_seen\": 5.0}, {\"site\": 249, \"mutant\": \"R\", \"log2 fold change IC90\": 0.2166830312351339, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.10161500544741951, \"functional effect\": 0.0234, \"times_seen\": 21.0}, {\"site\": 249, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04473873800148927, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.09019811362327351, \"functional effect\": 0.0032, \"times_seen\": 18.0}, {\"site\": 249, \"mutant\": \"V\", \"log2 fold change IC90\": -0.003700984369325137, \"epitope\": \"all\", \"reference_site\": \"252\", \"IC90\": 0.08721991227236772, \"functional effect\": 0.0587, \"times_seen\": 40.0}, {\"site\": 250, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": null, \"functional effect\": -2.9867, \"times_seen\": null}, {\"site\": 250, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0106232974567582, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08680241768519474, \"functional effect\": -1.3579, \"times_seen\": 1.0}, {\"site\": 250, \"mutant\": \"A\", \"log2 fold change IC90\": -0.1882230825491008, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.07674833439128931, \"functional effect\": -0.0694, \"times_seen\": 139.0}, {\"site\": 250, \"mutant\": \"C\", \"log2 fold change IC90\": 0.136320426943152, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.0961094939079907, \"functional effect\": -0.0911, \"times_seen\": 21.0}, {\"site\": 250, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 250, \"mutant\": \"E\", \"log2 fold change IC90\": 0.015320504439625812, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08837749430603156, \"functional effect\": 0.0047, \"times_seen\": 30.0}, {\"site\": 250, \"mutant\": \"F\", \"log2 fold change IC90\": 0.06901182843277157, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.09172851932984391, \"functional effect\": -0.19, \"times_seen\": 36.0}, {\"site\": 250, \"mutant\": \"G\", \"log2 fold change IC90\": -0.028042123087637625, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.085760683303864, \"functional effect\": -0.0226, \"times_seen\": 68.0}, {\"site\": 250, \"mutant\": \"H\", \"log2 fold change IC90\": -0.07118523281283762, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08323401846597067, \"functional effect\": 0.0066, \"times_seen\": 47.0}, {\"site\": 250, \"mutant\": \"I\", \"log2 fold change IC90\": 0.004277635514365224, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08770360586778168, \"functional effect\": -0.1172, \"times_seen\": 25.0}, {\"site\": 250, \"mutant\": \"K\", \"log2 fold change IC90\": -3.0234981473544953, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.010753903094211197, \"functional effect\": -0.0792, \"times_seen\": 18.0}, {\"site\": 250, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01688345789371175, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08642657955490181, \"functional effect\": -0.2095, \"times_seen\": 34.0}, {\"site\": 250, \"mutant\": \"M\", \"log2 fold change IC90\": -0.018272617330403598, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.0863434001502672, \"functional effect\": -0.0103, \"times_seen\": 6.0}, {\"site\": 250, \"mutant\": \"N\", \"log2 fold change IC90\": 0.4488960481985129, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.11936058214314295, \"functional effect\": 0.048, \"times_seen\": 86.0}, {\"site\": 250, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03625749142187302, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08527371041442355, \"functional effect\": -0.0621, \"times_seen\": 48.0}, {\"site\": 250, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03337356443594539, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08544434184379436, \"functional effect\": -0.0404, \"times_seen\": 14.0}, {\"site\": 250, \"mutant\": \"R\", \"log2 fold change IC90\": -0.3060195111420869, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.07073082125663331, \"functional effect\": -0.1955, \"times_seen\": 43.0}, {\"site\": 250, \"mutant\": \"S\", \"log2 fold change IC90\": -0.030924468261431276, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.08558951398674966, \"functional effect\": -0.0687, \"times_seen\": 85.0}, {\"site\": 250, \"mutant\": \"T\", \"log2 fold change IC90\": -0.958847908299081, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.044987076482759104, \"functional effect\": -0.1012, \"times_seen\": 52.0}, {\"site\": 250, \"mutant\": \"V\", \"log2 fold change IC90\": 0.26406061522789864, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.10500740320822242, \"functional effect\": -0.0993, \"times_seen\": 47.0}, {\"site\": 250, \"mutant\": \"W\", \"log2 fold change IC90\": -0.7516929098064985, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.05193350562905106, \"functional effect\": -0.2328, \"times_seen\": 15.0}, {\"site\": 250, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.14695753563645136, \"epitope\": \"all\", \"reference_site\": \"253\", \"IC90\": 0.07897527130314765, \"functional effect\": 0.0098, \"times_seen\": 89.0}, {\"site\": 251, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": null, \"functional effect\": -2.8802, \"times_seen\": null}, {\"site\": 251, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": null, \"functional effect\": -1.236, \"times_seen\": null}, {\"site\": 251, \"mutant\": \"A\", \"log2 fold change IC90\": 0.006410635018650307, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.087833370025746, \"functional effect\": -0.0229, \"times_seen\": 43.0}, {\"site\": 251, \"mutant\": \"C\", \"log2 fold change IC90\": 2.104405116829811, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.37602681485899825, \"functional effect\": -0.247, \"times_seen\": 19.0}, {\"site\": 251, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0065009909552084305, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.0878388711986994, \"functional effect\": 0.2769, \"times_seen\": 12.0}, {\"site\": 251, \"mutant\": \"E\", \"log2 fold change IC90\": -0.02427516782495812, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.0859849017108796, \"functional effect\": -0.1792, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04404519941942395, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08481464070172558, \"functional effect\": -0.0267, \"times_seen\": 55.0}, {\"site\": 251, \"mutant\": \"G\", \"log2 fold change IC90\": -0.06482247975059112, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08360191816617012, \"functional effect\": 0.1268, \"times_seen\": 17.0}, {\"site\": 251, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0023995097759010775, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08729863002873531, \"functional effect\": 0.0095, \"times_seen\": 14.0}, {\"site\": 251, \"mutant\": \"I\", \"log2 fold change IC90\": -2.320699672959139, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.017503687066237845, \"functional effect\": -0.1429, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"K\", \"log2 fold change IC90\": -0.030256695866914197, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08562913950875843, \"functional effect\": 0.1052, \"times_seen\": 10.0}, {\"site\": 251, \"mutant\": \"L\", \"log2 fold change IC90\": 0.014801147814758732, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08834568496645173, \"functional effect\": 0.0779, \"times_seen\": 47.0}, {\"site\": 251, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0035335655504106327, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08723003437134438, \"functional effect\": 0.1178, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"N\", \"log2 fold change IC90\": -0.026471946174130033, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08585407293022976, \"functional effect\": 0.2366, \"times_seen\": 13.0}, {\"site\": 251, \"mutant\": \"P\", \"log2 fold change IC90\": -0.07777534309016429, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08285467948542215, \"functional effect\": -0.0124, \"times_seen\": 98.0}, {\"site\": 251, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.004879466457564757, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08774019971002334, \"functional effect\": 0.1581, \"times_seen\": 9.0}, {\"site\": 251, \"mutant\": \"R\", \"log2 fold change IC90\": -0.4095605128783206, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.06583240989771776, \"functional effect\": -0.0805, \"times_seen\": 23.0}, {\"site\": 251, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 251, \"mutant\": \"T\", \"log2 fold change IC90\": -0.3756653911472365, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.06739740911621818, \"functional effect\": 0.0369, \"times_seen\": 72.0}, {\"site\": 251, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04486062661911958, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08476671607341701, \"functional effect\": -0.0644, \"times_seen\": 34.0}, {\"site\": 251, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0007233898869500816, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08748780385509612, \"functional effect\": -0.0808, \"times_seen\": 11.0}, {\"site\": 251, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.015752010592170348, \"epitope\": \"all\", \"reference_site\": \"254\", \"IC90\": 0.08649438700742074, \"functional effect\": 0.0042, \"times_seen\": 51.0}, {\"site\": 252, \"mutant\": \"*\", \"log2 fold change IC90\": -0.002447115327734152, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08729574942627097, \"functional effect\": -2.7623, \"times_seen\": 2.0}, {\"site\": 252, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 252, \"mutant\": \"A\", \"log2 fold change IC90\": 0.10813377107125109, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.09424997885860624, \"functional effect\": 0.022, \"times_seen\": 34.0}, {\"site\": 252, \"mutant\": \"C\", \"log2 fold change IC90\": 0.004560250022292625, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08772078811254566, \"functional effect\": -0.1201, \"times_seen\": 9.0}, {\"site\": 252, \"mutant\": \"D\", \"log2 fold change IC90\": 0.05032789559571469, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.090548228685572, \"functional effect\": 0.2949, \"times_seen\": 17.0}, {\"site\": 252, \"mutant\": \"E\", \"log2 fold change IC90\": -0.001058265156895167, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08737982755065431, \"functional effect\": -0.1349, \"times_seen\": 10.0}, {\"site\": 252, \"mutant\": \"F\", \"log2 fold change IC90\": 0.1354458845762631, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.09605125127770196, \"functional effect\": -0.09, \"times_seen\": 63.0}, {\"site\": 252, \"mutant\": \"G\", \"log2 fold change IC90\": -0.004612960972483804, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08716479502194475, \"functional effect\": 0.0354, \"times_seen\": 16.0}, {\"site\": 252, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0179928740717932, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08636014403955239, \"functional effect\": -0.2111, \"times_seen\": 9.0}, {\"site\": 252, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03066875639326369, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08560468572688631, \"functional effect\": 0.0747, \"times_seen\": 19.0}, {\"site\": 252, \"mutant\": \"K\", \"log2 fold change IC90\": -0.007683636802503277, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.086979468129301, \"functional effect\": 0.1087, \"times_seen\": 11.0}, {\"site\": 252, \"mutant\": \"L\", \"log2 fold change IC90\": -1.2810123518373306, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.03598376568444827, \"functional effect\": -0.0646, \"times_seen\": 45.0}, {\"site\": 252, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01483792823658282, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08654920666297752, \"functional effect\": -0.1899, \"times_seen\": 5.0}, {\"site\": 252, \"mutant\": \"N\", \"log2 fold change IC90\": 0.017164213858336157, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08849050958334806, \"functional effect\": -0.2301, \"times_seen\": 8.0}, {\"site\": 252, \"mutant\": \"P\", \"log2 fold change IC90\": -0.2936073230525239, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.0713419772425033, \"functional effect\": 0.0354, \"times_seen\": 94.0}, {\"site\": 252, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0001014842657864676, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08745009842878747, \"functional effect\": 0.3266, \"times_seen\": 4.0}, {\"site\": 252, \"mutant\": \"R\", \"log2 fold change IC90\": -0.006613620797136292, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08704400286653294, \"functional effect\": -0.222, \"times_seen\": 16.0}, {\"site\": 252, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 252, \"mutant\": \"T\", \"log2 fold change IC90\": -1.4403179053020423, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.032221878820889, \"functional effect\": 0.0208, \"times_seen\": 45.0}, {\"site\": 252, \"mutant\": \"V\", \"log2 fold change IC90\": 0.01735143515693066, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08850199391141467, \"functional effect\": -0.0605, \"times_seen\": 16.0}, {\"site\": 252, \"mutant\": \"W\", \"log2 fold change IC90\": 0.022689790494857674, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08883008145734894, \"functional effect\": -0.1098, \"times_seen\": 9.0}, {\"site\": 252, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.016207272489059777, \"epitope\": \"all\", \"reference_site\": \"255\", \"IC90\": 0.08843183318329924, \"functional effect\": 0.0438, \"times_seen\": 43.0}, {\"site\": 253, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 253, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02439990601591522, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08597746761211279, \"functional effect\": 0.2278, \"times_seen\": 9.0}, {\"site\": 253, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0023077711952608835, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08730418138007258, \"functional effect\": -0.0983, \"times_seen\": 1.0}, {\"site\": 253, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009684377503533851, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08685892792891375, \"functional effect\": -0.1115, \"times_seen\": 2.0}, {\"site\": 253, \"mutant\": \"L\", \"log2 fold change IC90\": 0.05251477762333189, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.09068558858862508, \"functional effect\": -0.0324, \"times_seen\": 27.0}, {\"site\": 253, \"mutant\": \"P\", \"log2 fold change IC90\": -0.11240294724810435, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08088967567004025, \"functional effect\": 0.0483, \"times_seen\": 40.0}, {\"site\": 253, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 253, \"mutant\": \"T\", \"log2 fold change IC90\": -0.018083774605044213, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.0863547028786573, \"functional effect\": -0.3463, \"times_seen\": 12.0}, {\"site\": 253, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.016580294238695337, \"epitope\": \"all\", \"reference_site\": \"256\", \"IC90\": 0.08644474288820551, \"functional effect\": 0.3442, \"times_seen\": 5.0}, {\"site\": 254, \"mutant\": \"*\", \"log2 fold change IC90\": -0.014613452887220024, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08656267428738026, \"functional effect\": -3.1202, \"times_seen\": 2.0}, {\"site\": 254, \"mutant\": \"A\", \"log2 fold change IC90\": 0.013416350432202469, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08826092542056808, \"functional effect\": 0.0133, \"times_seen\": 21.0}, {\"site\": 254, \"mutant\": \"C\", \"log2 fold change IC90\": 0.11636781277318946, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.09478943944597641, \"functional effect\": -0.1041, \"times_seen\": 14.0}, {\"site\": 254, \"mutant\": \"D\", \"log2 fold change IC90\": -0.14277636213345835, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.07920448694894919, \"functional effect\": -0.0256, \"times_seen\": 54.0}, {\"site\": 254, \"mutant\": \"E\", \"log2 fold change IC90\": -0.006458210062757225, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08705337997026143, \"functional effect\": 0.0481, \"times_seen\": 12.0}, {\"site\": 254, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04374217507368513, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08483245707981164, \"functional effect\": 0.0854, \"times_seen\": 10.0}, {\"site\": 254, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 254, \"mutant\": \"H\", \"log2 fold change IC90\": 0.07088453034241274, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.09184766558530333, \"functional effect\": 0.2371, \"times_seen\": 9.0}, {\"site\": 254, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02059790245423658, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08620434698541377, \"functional effect\": -0.104, \"times_seen\": 6.0}, {\"site\": 254, \"mutant\": \"K\", \"log2 fold change IC90\": -0.012707727150437597, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0866770946704043, \"functional effect\": -0.1809, \"times_seen\": 10.0}, {\"site\": 254, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01428435956738035, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08831404429801343, \"functional effect\": 0.0541, \"times_seen\": 16.0}, {\"site\": 254, \"mutant\": \"M\", \"log2 fold change IC90\": 0.015187769826756342, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0883693635420548, \"functional effect\": 0.1249, \"times_seen\": 8.0}, {\"site\": 254, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01777949371639552, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08852825702021168, \"functional effect\": 0.0088, \"times_seen\": 18.0}, {\"site\": 254, \"mutant\": \"P\", \"log2 fold change IC90\": 0.3398039146563812, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.11066771010484591, \"functional effect\": -0.0566, \"times_seen\": 18.0}, {\"site\": 254, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009427238232022923, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08687441064103678, \"functional effect\": 0.1361, \"times_seen\": 3.0}, {\"site\": 254, \"mutant\": \"R\", \"log2 fold change IC90\": -0.058657007204210715, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08395996216416979, \"functional effect\": -0.0423, \"times_seen\": 21.0}, {\"site\": 254, \"mutant\": \"S\", \"log2 fold change IC90\": 0.38793619517129196, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.11442217108913769, \"functional effect\": -0.0097, \"times_seen\": 41.0}, {\"site\": 254, \"mutant\": \"T\", \"log2 fold change IC90\": -1.0697710069779394, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.041657825001114535, \"functional effect\": -0.021, \"times_seen\": 13.0}, {\"site\": 254, \"mutant\": \"V\", \"log2 fold change IC90\": 0.021025642289486706, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08872767506489299, \"functional effect\": -0.0902, \"times_seen\": 27.0}, {\"site\": 254, \"mutant\": \"W\", \"log2 fold change IC90\": -0.033047690247462534, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.08546364408695911, \"functional effect\": -0.2542, \"times_seen\": 10.0}, {\"site\": 254, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0008480354857028417, \"epitope\": \"all\", \"reference_site\": \"257\", \"IC90\": 0.0874953629306332, \"functional effect\": -0.3191, \"times_seen\": 5.0}, {\"site\": 255, \"mutant\": \"*\", \"log2 fold change IC90\": 0.041091506802179455, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08997037464762232, \"functional effect\": -1.9373, \"times_seen\": 5.0}, {\"site\": 255, \"mutant\": \"C\", \"log2 fold change IC90\": 0.005487631127468571, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08777719417985631, \"functional effect\": 0.0905, \"times_seen\": 42.0}, {\"site\": 255, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0005795036028669498, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08740882955245008, \"functional effect\": -0.1519, \"times_seen\": 6.0}, {\"site\": 255, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04177115843555651, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08494843478166819, \"functional effect\": 0.2637, \"times_seen\": 10.0}, {\"site\": 255, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01859865165489636, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08632388962955762, \"functional effect\": -0.1184, \"times_seen\": 15.0}, {\"site\": 255, \"mutant\": \"R\", \"log2 fold change IC90\": 0.036514516770159024, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.0896853934330514, \"functional effect\": -0.1066, \"times_seen\": 52.0}, {\"site\": 255, \"mutant\": \"S\", \"log2 fold change IC90\": 0.028530528081284975, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.08919043818228717, \"functional effect\": -0.0135, \"times_seen\": 7.0}, {\"site\": 255, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"258\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 256, \"mutant\": \"A\", \"log2 fold change IC90\": -0.022523050819403232, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08608939165852238, \"functional effect\": -0.0462, \"times_seen\": 21.0}, {\"site\": 256, \"mutant\": \"I\", \"log2 fold change IC90\": -0.3109063830178566, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.07049163855078809, \"functional effect\": 0.0035, \"times_seen\": 53.0}, {\"site\": 256, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02641960274697842, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08585718791836572, \"functional effect\": 0.1198, \"times_seen\": 19.0}, {\"site\": 256, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0051618208797613386, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08713164029365465, \"functional effect\": 0.3663, \"times_seen\": 1.0}, {\"site\": 256, \"mutant\": \"P\", \"log2 fold change IC90\": 0.015431599725847815, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08838430011099296, \"functional effect\": 0.0819, \"times_seen\": 8.0}, {\"site\": 256, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011307273782838651, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08676127473706788, \"functional effect\": 0.059, \"times_seen\": 11.0}, {\"site\": 256, \"mutant\": \"S\", \"log2 fold change IC90\": -0.062438205815503155, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08374019733887154, \"functional effect\": 0.377, \"times_seen\": 5.0}, {\"site\": 256, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 256, \"mutant\": \"V\", \"log2 fold change IC90\": 0.008953937851298787, \"epitope\": \"all\", \"reference_site\": \"259\", \"IC90\": 0.08798834655971606, \"functional effect\": -0.159, \"times_seen\": 3.0}, {\"site\": 257, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": null, \"functional effect\": -0.0857, \"times_seen\": null}, {\"site\": 257, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 257, \"mutant\": \"D\", \"log2 fold change IC90\": -1.4130773446059204, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.032836063428118796, \"functional effect\": 0.0856, \"times_seen\": 52.0}, {\"site\": 257, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0040294251902599915, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.0872000582365423, \"functional effect\": 0.0222, \"times_seen\": 2.0}, {\"site\": 257, \"mutant\": \"F\", \"log2 fold change IC90\": -0.012116532879339302, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08671262089118127, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 257, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05025488515169213, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08445036383408426, \"functional effect\": 0.181, \"times_seen\": 14.0}, {\"site\": 257, \"mutant\": \"I\", \"log2 fold change IC90\": -0.023808883723728157, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08601269682442597, \"functional effect\": -0.042, \"times_seen\": 6.0}, {\"site\": 257, \"mutant\": \"P\", \"log2 fold change IC90\": -0.013936401197508138, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08660330737857865, \"functional effect\": 0.1285, \"times_seen\": 9.0}, {\"site\": 257, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": null, \"functional effect\": 0.0593, \"times_seen\": null}, {\"site\": 257, \"mutant\": \"S\", \"log2 fold change IC90\": -0.043151508749973755, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.08486719618478111, \"functional effect\": -0.131, \"times_seen\": 36.0}, {\"site\": 257, \"mutant\": \"T\", \"log2 fold change IC90\": 0.375783589268802, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.11346237893835617, \"functional effect\": 0.0958, \"times_seen\": 46.0}, {\"site\": 257, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1887963884216334, \"epitope\": \"all\", \"reference_site\": \"260\", \"IC90\": 0.0767178417866894, \"functional effect\": 0.0007, \"times_seen\": 71.0}, {\"site\": 258, \"mutant\": \"*\", \"log2 fold change IC90\": -0.011365121508742299, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08675779594101125, \"functional effect\": -2.9356, \"times_seen\": 2.0}, {\"site\": 258, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": null, \"functional effect\": -1.6178, \"times_seen\": null}, {\"site\": 258, \"mutant\": \"A\", \"log2 fold change IC90\": 0.756895749034675, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.14776721116022887, \"functional effect\": -0.0449, \"times_seen\": 78.0}, {\"site\": 258, \"mutant\": \"C\", \"log2 fold change IC90\": -0.16791690470636436, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07783621835467959, \"functional effect\": 0.0783, \"times_seen\": 58.0}, {\"site\": 258, \"mutant\": \"D\", \"log2 fold change IC90\": -0.7379382306481775, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.05243100839008059, \"functional effect\": 0.0359, \"times_seen\": 73.0}, {\"site\": 258, \"mutant\": \"E\", \"log2 fold change IC90\": -0.11382475294995459, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08080999649642781, \"functional effect\": -0.1557, \"times_seen\": 30.0}, {\"site\": 258, \"mutant\": \"F\", \"log2 fold change IC90\": -0.10485896878608182, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08131376268166508, \"functional effect\": 0.0559, \"times_seen\": 31.0}, {\"site\": 258, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 258, \"mutant\": \"H\", \"log2 fold change IC90\": 0.23719500740917768, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.10307006854721464, \"functional effect\": -0.0955, \"times_seen\": 20.0}, {\"site\": 258, \"mutant\": \"I\", \"log2 fold change IC90\": -0.14319005539009758, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07918177829342289, \"functional effect\": 0.0601, \"times_seen\": 23.0}, {\"site\": 258, \"mutant\": \"K\", \"log2 fold change IC90\": -1.16869650911308, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.03889708426752745, \"functional effect\": 0.067, \"times_seen\": 5.0}, {\"site\": 258, \"mutant\": \"L\", \"log2 fold change IC90\": 0.5027251957012722, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.12389823404563495, \"functional effect\": 0.0457, \"times_seen\": 58.0}, {\"site\": 258, \"mutant\": \"M\", \"log2 fold change IC90\": -0.028080937344021294, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08575837603013164, \"functional effect\": -0.0449, \"times_seen\": 9.0}, {\"site\": 258, \"mutant\": \"N\", \"log2 fold change IC90\": -1.8466760453912363, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.02431223421296472, \"functional effect\": 0.0278, \"times_seen\": 29.0}, {\"site\": 258, \"mutant\": \"P\", \"log2 fold change IC90\": 0.25859933463691726, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.1046106521216771, \"functional effect\": -0.047, \"times_seen\": 37.0}, {\"site\": 258, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0024584075326126017, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08759308195652445, \"functional effect\": 0.3115, \"times_seen\": 12.0}, {\"site\": 258, \"mutant\": \"R\", \"log2 fold change IC90\": -0.15342562929763287, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.0786219907707048, \"functional effect\": -0.0097, \"times_seen\": 93.0}, {\"site\": 258, \"mutant\": \"S\", \"log2 fold change IC90\": 0.14043237572408682, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.09638381456025243, \"functional effect\": 0.0399, \"times_seen\": 92.0}, {\"site\": 258, \"mutant\": \"T\", \"log2 fold change IC90\": -0.2200801716979722, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07507217866663769, \"functional effect\": -0.0641, \"times_seen\": 34.0}, {\"site\": 258, \"mutant\": \"V\", \"log2 fold change IC90\": -0.14075655406534374, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.07931545281211293, \"functional effect\": 0.0049, \"times_seen\": 61.0}, {\"site\": 258, \"mutant\": \"W\", \"log2 fold change IC90\": -0.10977886697809648, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08103693767000153, \"functional effect\": -0.0953, \"times_seen\": 10.0}, {\"site\": 258, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009813940814337943, \"epitope\": \"all\", \"reference_site\": \"261\", \"IC90\": 0.08685112778775932, \"functional effect\": -0.0368, \"times_seen\": 28.0}, {\"site\": 259, \"mutant\": \"*\", \"log2 fold change IC90\": -0.017045456420510526, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08641687536093144, \"functional effect\": -2.1507, \"times_seen\": 3.0}, {\"site\": 259, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": null, \"functional effect\": 1.1621, \"times_seen\": null}, {\"site\": 259, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 259, \"mutant\": \"C\", \"log2 fold change IC90\": 0.11712544713778816, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.09483923139443683, \"functional effect\": 0.1069, \"times_seen\": 32.0}, {\"site\": 259, \"mutant\": \"D\", \"log2 fold change IC90\": 1.212829081448539, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.202687835998286, \"functional effect\": 0.0076, \"times_seen\": 35.0}, {\"site\": 259, \"mutant\": \"E\", \"log2 fold change IC90\": 0.04022906954667021, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08991660679455576, \"functional effect\": 0.0609, \"times_seen\": 17.0}, {\"site\": 259, \"mutant\": \"F\", \"log2 fold change IC90\": 0.04596631616036583, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.09027489516899671, \"functional effect\": 0.0082, \"times_seen\": 17.0}, {\"site\": 259, \"mutant\": \"G\", \"log2 fold change IC90\": -0.018327712359514765, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08634010284822002, \"functional effect\": 0.0203, \"times_seen\": 31.0}, {\"site\": 259, \"mutant\": \"H\", \"log2 fold change IC90\": -0.015794687544630603, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08649182841940238, \"functional effect\": -0.0365, \"times_seen\": 17.0}, {\"site\": 259, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05150211108847218, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08437738710278125, \"functional effect\": 0.0746, \"times_seen\": 13.0}, {\"site\": 259, \"mutant\": \"K\", \"log2 fold change IC90\": -0.019338390442050414, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08627963858612687, \"functional effect\": 0.1179, \"times_seen\": 14.0}, {\"site\": 259, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04947020906698828, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08449630854394324, \"functional effect\": 0.0299, \"times_seen\": 46.0}, {\"site\": 259, \"mutant\": \"M\", \"log2 fold change IC90\": -0.008573621316649514, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08692582788964882, \"functional effect\": 0.0169, \"times_seen\": 10.0}, {\"site\": 259, \"mutant\": \"N\", \"log2 fold change IC90\": -0.009116674672173843, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08689311378315394, \"functional effect\": 0.0233, \"times_seen\": 10.0}, {\"site\": 259, \"mutant\": \"P\", \"log2 fold change IC90\": -0.13506336292789345, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.07962906737851166, \"functional effect\": -0.0905, \"times_seen\": 56.0}, {\"site\": 259, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.030759883359193906, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.0893283681510719, \"functional effect\": 0.066, \"times_seen\": 7.0}, {\"site\": 259, \"mutant\": \"R\", \"log2 fold change IC90\": 0.17223945190261047, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.09853238481035408, \"functional effect\": 0.102, \"times_seen\": 43.0}, {\"site\": 259, \"mutant\": \"S\", \"log2 fold change IC90\": -1.4630103382641344, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.03171901972790896, \"functional effect\": 0.0822, \"times_seen\": 96.0}, {\"site\": 259, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06848516467000883, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08338994050749199, \"functional effect\": 0.012, \"times_seen\": 76.0}, {\"site\": 259, \"mutant\": \"V\", \"log2 fold change IC90\": -0.29604718437388233, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.07122142686880321, \"functional effect\": -0.0147, \"times_seen\": 84.0}, {\"site\": 259, \"mutant\": \"W\", \"log2 fold change IC90\": -0.05468171958619857, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.08419162945983844, \"functional effect\": 0.0732, \"times_seen\": 15.0}, {\"site\": 259, \"mutant\": \"Y\", \"log2 fold change IC90\": 1.0507419610824917, \"epitope\": \"all\", \"reference_site\": \"262\", \"IC90\": 0.18114844102150138, \"functional effect\": 0.2595, \"times_seen\": 16.0}, {\"site\": 260, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 260, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02117576309292374, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08616982539727787, \"functional effect\": -0.0939, \"times_seen\": 7.0}, {\"site\": 260, \"mutant\": \"E\", \"log2 fold change IC90\": -0.10361332039670253, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08138400073912923, \"functional effect\": -0.0353, \"times_seen\": 12.0}, {\"site\": 260, \"mutant\": \"G\", \"log2 fold change IC90\": 0.02147597888083334, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08875537569086897, \"functional effect\": -0.055, \"times_seen\": 5.0}, {\"site\": 260, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0022450957483966757, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08730797424501278, \"functional effect\": -0.1135, \"times_seen\": 5.0}, {\"site\": 260, \"mutant\": \"L\", \"log2 fold change IC90\": -0.003295538677734147, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.08724442743752782, \"functional effect\": 0.2737, \"times_seen\": 3.0}, {\"site\": 260, \"mutant\": \"P\", \"log2 fold change IC90\": -0.038448068451669766, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.0851443297200018, \"functional effect\": -0.0926, \"times_seen\": 8.0}, {\"site\": 260, \"mutant\": \"R\", \"log2 fold change IC90\": 0.04273585128909612, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.0900729788901529, \"functional effect\": -0.3805, \"times_seen\": 3.0}, {\"site\": 260, \"mutant\": \"S\", \"log2 fold change IC90\": 0.06958331880321285, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.09176486266523584, \"functional effect\": 0.0867, \"times_seen\": 15.0}, {\"site\": 260, \"mutant\": \"T\", \"log2 fold change IC90\": 0.3320259283208709, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.11007267391103291, \"functional effect\": -0.1126, \"times_seen\": 72.0}, {\"site\": 260, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0873651600386832, \"epitope\": \"all\", \"reference_site\": \"263\", \"IC90\": 0.0823057580272602, \"functional effect\": -0.1314, \"times_seen\": 57.0}, {\"site\": 261, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 261, \"mutant\": \"D\", \"log2 fold change IC90\": -0.005279024554464667, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.0871245620592858, \"functional effect\": -0.0692, \"times_seen\": 25.0}, {\"site\": 261, \"mutant\": \"G\", \"log2 fold change IC90\": 0.03046186329770086, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.08930991733813906, \"functional effect\": -0.1399, \"times_seen\": 1.0}, {\"site\": 261, \"mutant\": \"L\", \"log2 fold change IC90\": 0.47743045946713936, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.12174486206425573, \"functional effect\": -0.3907, \"times_seen\": 4.0}, {\"site\": 261, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": null, \"functional effect\": 0.0343, \"times_seen\": null}, {\"site\": 261, \"mutant\": \"S\", \"log2 fold change IC90\": 0.3269211305408162, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.10968388363142856, \"functional effect\": 0.007, \"times_seen\": 45.0}, {\"site\": 261, \"mutant\": \"T\", \"log2 fold change IC90\": -0.5274183692715476, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.060668185137761926, \"functional effect\": -0.1058, \"times_seen\": 39.0}, {\"site\": 261, \"mutant\": \"V\", \"log2 fold change IC90\": 1.128002505965084, \"epitope\": \"all\", \"reference_site\": \"264\", \"IC90\": 0.19111392957699305, \"functional effect\": -0.1244, \"times_seen\": 29.0}, {\"site\": 262, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0045698322985076355, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.08716740081049464, \"functional effect\": -3.1472, \"times_seen\": 1.0}, {\"site\": 262, \"mutant\": \"C\", \"log2 fold change IC90\": -0.22786007845996967, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.07466843250502678, \"functional effect\": 0.0624, \"times_seen\": 41.0}, {\"site\": 262, \"mutant\": \"F\", \"log2 fold change IC90\": -0.024717914987927605, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.08595851794352469, \"functional effect\": 0.0345, \"times_seen\": 26.0}, {\"site\": 262, \"mutant\": \"H\", \"log2 fold change IC90\": 0.06032615356116708, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.0911779313265691, \"functional effect\": -0.1187, \"times_seen\": 15.0}, {\"site\": 262, \"mutant\": \"L\", \"log2 fold change IC90\": 0.07572300039987355, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.09215621882262755, \"functional effect\": -0.2799, \"times_seen\": 5.0}, {\"site\": 262, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 262, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"265\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 263, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": null, \"functional effect\": -3.1313, \"times_seen\": null}, {\"site\": 263, \"mutant\": \"C\", \"log2 fold change IC90\": -0.015419512358951646, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.08651432368452557, \"functional effect\": -0.6806, \"times_seen\": 13.0}, {\"site\": 263, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": null, \"functional effect\": -2.7898, \"times_seen\": null}, {\"site\": 263, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0024005540949004894, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.08758956946139433, \"functional effect\": -0.254, \"times_seen\": 3.0}, {\"site\": 263, \"mutant\": \"H\", \"log2 fold change IC90\": 0.023874286828518627, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.08890304359321263, \"functional effect\": -0.2097, \"times_seen\": 24.0}, {\"site\": 263, \"mutant\": \"L\", \"log2 fold change IC90\": 0.055478867138233925, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.09087209822207838, \"functional effect\": -0.1006, \"times_seen\": 8.0}, {\"site\": 263, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004370566569508474, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.0871794412450775, \"functional effect\": -0.1918, \"times_seen\": 1.0}, {\"site\": 263, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.044039416559459574, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.09015440224442142, \"functional effect\": -0.548, \"times_seen\": 3.0}, {\"site\": 263, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"266\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 264, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00449071758228159, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.08717218103990927, \"functional effect\": -0.0664, \"times_seen\": 1.0}, {\"site\": 264, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": null, \"functional effect\": -0.5584, \"times_seen\": null}, {\"site\": 264, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": null, \"functional effect\": -2.6471, \"times_seen\": null}, {\"site\": 264, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010853015624281676, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.0867885973667415, \"functional effect\": -0.3599, \"times_seen\": 38.0}, {\"site\": 264, \"mutant\": \"M\", \"log2 fold change IC90\": -0.07451999363470006, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.0830418468778074, \"functional effect\": -0.3533, \"times_seen\": 31.0}, {\"site\": 264, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"267\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 265, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 265, \"mutant\": \"C\", \"log2 fold change IC90\": -0.008594572639309454, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08692456553149834, \"functional effect\": -2.9919, \"times_seen\": 3.0}, {\"site\": 265, \"mutant\": \"D\", \"log2 fold change IC90\": -0.021272782446779912, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08616403078410804, \"functional effect\": -2.289, \"times_seen\": 4.0}, {\"site\": 265, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 265, \"mutant\": \"N\", \"log2 fold change IC90\": -0.011178899347736018, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08676899530508253, \"functional effect\": -2.2112, \"times_seen\": 1.0}, {\"site\": 265, \"mutant\": \"S\", \"log2 fold change IC90\": -0.357365301114772, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.06825776719039275, \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 265, \"mutant\": \"V\", \"log2 fold change IC90\": -0.008521049266028924, \"epitope\": \"all\", \"reference_site\": \"268\", \"IC90\": 0.08692899553919287, \"functional effect\": -2.8801, \"times_seen\": 1.0}, {\"site\": 266, \"mutant\": \"*\", \"log2 fold change IC90\": 0.006159667409116048, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08781809208196861, \"functional effect\": -3.0861, \"times_seen\": 1.0}, {\"site\": 266, \"mutant\": \"C\", \"log2 fold change IC90\": 1.899701516820151, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.32628483724512697, \"functional effect\": -0.3971, \"times_seen\": 15.0}, {\"site\": 266, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04083555683439222, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08500354252516559, \"functional effect\": -0.0674, \"times_seen\": 13.0}, {\"site\": 266, \"mutant\": \"H\", \"log2 fold change IC90\": -0.09184052699145656, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08205083392708493, \"functional effect\": -0.0208, \"times_seen\": 42.0}, {\"site\": 266, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0032340809540469294, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08764018955173106, \"functional effect\": -0.4324, \"times_seen\": 8.0}, {\"site\": 266, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": null, \"functional effect\": 0.0884, \"times_seen\": null}, {\"site\": 266, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": null, \"functional effect\": 0.7108, \"times_seen\": null}, {\"site\": 266, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03254830387767066, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.08943917171188186, \"functional effect\": -0.226, \"times_seen\": 2.0}, {\"site\": 266, \"mutant\": \"S\", \"log2 fold change IC90\": 0.09975861801605598, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.09370442265487715, \"functional effect\": -1.7952, \"times_seen\": 1.0}, {\"site\": 266, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"269\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"F\", \"log2 fold change IC90\": -0.002140184133627425, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08731432344103054, \"functional effect\": -2.5755, \"times_seen\": 3.0}, {\"site\": 267, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004373161503939318, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08717928443804351, \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 267, \"mutant\": \"I\", \"log2 fold change IC90\": -0.09089304698678151, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08210473794422146, \"functional effect\": 0.0225, \"times_seen\": 29.0}, {\"site\": 267, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013431209326391046, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08663363877003585, \"functional effect\": -0.3297, \"times_seen\": 6.0}, {\"site\": 267, \"mutant\": \"P\", \"log2 fold change IC90\": -0.008620160845460292, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08692302381691941, \"functional effect\": -2.1117, \"times_seen\": 4.0}, {\"site\": 267, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": null, \"functional effect\": -2.2507, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": null, \"functional effect\": -2.5835, \"times_seen\": null}, {\"site\": 267, \"mutant\": \"V\", \"log2 fold change IC90\": -0.00912344877488875, \"epitope\": \"all\", \"reference_site\": \"270\", \"IC90\": 0.08689270578182352, \"functional effect\": -0.1038, \"times_seen\": 1.0}, {\"site\": 268, \"mutant\": \"*\", \"log2 fold change IC90\": -0.009888550458051718, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08684663635751018, \"functional effect\": -2.8702, \"times_seen\": 2.0}, {\"site\": 268, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0751175935593395, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.09211755486443741, \"functional effect\": -0.2675, \"times_seen\": 8.0}, {\"site\": 268, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004906749903271731, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08714704668013691, \"functional effect\": 0.1361, \"times_seen\": 1.0}, {\"site\": 268, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03479184275660076, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08957836700811739, \"functional effect\": 0.0575, \"times_seen\": 48.0}, {\"site\": 268, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05625749505416193, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08409972183246169, \"functional effect\": -0.1649, \"times_seen\": 19.0}, {\"site\": 268, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": null, \"functional effect\": -1.7877, \"times_seen\": null}, {\"site\": 268, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 268, \"mutant\": \"R\", \"log2 fold change IC90\": -0.02953362466115222, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08567206714208986, \"functional effect\": -0.037, \"times_seen\": 6.0}, {\"site\": 268, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": null, \"functional effect\": -0.1829, \"times_seen\": null}, {\"site\": 268, \"mutant\": \"V\", \"log2 fold change IC90\": 0.010052064429746462, \"epitope\": \"all\", \"reference_site\": \"271\", \"IC90\": 0.08805534555897473, \"functional effect\": -0.0978, \"times_seen\": 8.0}, {\"site\": 269, \"mutant\": \"F\", \"log2 fold change IC90\": -0.007884169626608649, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08696737893115432, \"functional effect\": 0.3883, \"times_seen\": 10.0}, {\"site\": 269, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06294439971415998, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.0837108208315537, \"functional effect\": 0.1072, \"times_seen\": 27.0}, {\"site\": 269, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": null, \"functional effect\": 0.2025, \"times_seen\": null}, {\"site\": 269, \"mutant\": \"L\", \"log2 fold change IC90\": -0.12182254587858733, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08036325378792887, \"functional effect\": 0.2079, \"times_seen\": 37.0}, {\"site\": 269, \"mutant\": \"M\", \"log2 fold change IC90\": 0.029642853848358724, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08925923101435304, \"functional effect\": -0.0532, \"times_seen\": 7.0}, {\"site\": 269, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 269, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03282947108086064, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08945660423344748, \"functional effect\": -0.0278, \"times_seen\": 5.0}, {\"site\": 269, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": null, \"functional effect\": -3.2083, \"times_seen\": null}, {\"site\": 269, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02062359074865695, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08870295180237428, \"functional effect\": -0.0187, \"times_seen\": 20.0}, {\"site\": 269, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07367023748787925, \"epitope\": \"all\", \"reference_site\": \"272\", \"IC90\": 0.08309077343789745, \"functional effect\": 0.0631, \"times_seen\": 40.0}, {\"site\": 270, \"mutant\": \"E\", \"log2 fold change IC90\": -0.015128671481529011, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08653176634394477, \"functional effect\": -2.5379, \"times_seen\": 4.0}, {\"site\": 270, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0028168971687177716, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.087614850322597, \"functional effect\": -0.5758, \"times_seen\": 18.0}, {\"site\": 270, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": null, \"functional effect\": -1.3479, \"times_seen\": null}, {\"site\": 270, \"mutant\": \"K\", \"log2 fold change IC90\": 0.4094887085617413, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.1161443631530174, \"functional effect\": -0.2049, \"times_seen\": 34.0}, {\"site\": 270, \"mutant\": \"M\", \"log2 fold change IC90\": 0.05700474071468977, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.09096826039239642, \"functional effect\": -1.3312, \"times_seen\": 30.0}, {\"site\": 270, \"mutant\": \"Q\", \"log2 fold change IC90\": 1.6637204433799677, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.2770508651537751, \"functional effect\": -1.0518, \"times_seen\": 6.0}, {\"site\": 270, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 270, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07314548254456468, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08312100174229625, \"functional effect\": -0.272, \"times_seen\": 37.0}, {\"site\": 270, \"mutant\": \"T\", \"log2 fold change IC90\": 0.008147742337878386, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": 0.08793919133840111, \"functional effect\": -0.7768, \"times_seen\": 18.0}, {\"site\": 270, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"273\", \"IC90\": null, \"functional effect\": -0.7758, \"times_seen\": null}, {\"site\": 271, \"mutant\": \"A\", \"log2 fold change IC90\": -0.005417508946270626, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08711619936822093, \"functional effect\": 0.0215, \"times_seen\": 5.0}, {\"site\": 271, \"mutant\": \"D\", \"log2 fold change IC90\": -0.005763895054326519, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08709528557970375, \"functional effect\": -0.5077, \"times_seen\": 1.0}, {\"site\": 271, \"mutant\": \"I\", \"log2 fold change IC90\": -0.11333007988198782, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08083770947928111, \"functional effect\": -0.1285, \"times_seen\": 48.0}, {\"site\": 271, \"mutant\": \"L\", \"log2 fold change IC90\": 0.003910475155321479, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08768128847616198, \"functional effect\": -0.8816, \"times_seen\": 2.0}, {\"site\": 271, \"mutant\": \"N\", \"log2 fold change IC90\": 0.11611738246434673, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.0947729868432101, \"functional effect\": -0.1565, \"times_seen\": 10.0}, {\"site\": 271, \"mutant\": \"P\", \"log2 fold change IC90\": 0.013378302379112998, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08825859775463787, \"functional effect\": -0.5376, \"times_seen\": 5.0}, {\"site\": 271, \"mutant\": \"S\", \"log2 fold change IC90\": 0.018587401408572866, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.08857784663398284, \"functional effect\": -0.0026, \"times_seen\": 2.0}, {\"site\": 271, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"274\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"C\", \"log2 fold change IC90\": -0.053529475841601656, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.08425889802691328, \"functional effect\": -2.604, \"times_seen\": 3.0}, {\"site\": 272, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"I\", \"log2 fold change IC90\": 0.020967084849228292, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.08872407377706512, \"functional effect\": -0.4407, \"times_seen\": 17.0}, {\"site\": 272, \"mutant\": \"L\", \"log2 fold change IC90\": -0.138613856455714, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": 0.07943334002554958, \"functional effect\": 0.1596, \"times_seen\": 22.0}, {\"site\": 272, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": null, \"functional effect\": -2.9369, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": null, \"functional effect\": -0.5865, \"times_seen\": null}, {\"site\": 272, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"275\", \"IC90\": null, \"functional effect\": -0.1679, \"times_seen\": null}, {\"site\": 273, \"mutant\": \"I\", \"log2 fold change IC90\": 0.016172353804298087, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.08842969282386853, \"functional effect\": -0.8345, \"times_seen\": 5.0}, {\"site\": 273, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 273, \"mutant\": \"M\", \"log2 fold change IC90\": 2.3732591778810264, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.4530560694124412, \"functional effect\": -0.0186, \"times_seen\": 8.0}, {\"site\": 273, \"mutant\": \"P\", \"log2 fold change IC90\": 0.050712000187872, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.09057233954739995, \"functional effect\": -3.0628, \"times_seen\": 1.0}, {\"site\": 273, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03459233595690796, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.08956598028939221, \"functional effect\": -0.9047, \"times_seen\": 8.0}, {\"site\": 273, \"mutant\": \"S\", \"log2 fold change IC90\": 0.005707623663679158, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.0877905800995313, \"functional effect\": -2.8821, \"times_seen\": 2.0}, {\"site\": 273, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011201431839883202, \"epitope\": \"all\", \"reference_site\": \"276\", \"IC90\": 0.08676764012856765, \"functional effect\": -0.9254, \"times_seen\": 7.0}, {\"site\": 274, \"mutant\": \"F\", \"log2 fold change IC90\": 0.006230647324471867, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.08782241279695464, \"functional effect\": 0.1495, \"times_seen\": 13.0}, {\"site\": 274, \"mutant\": \"I\", \"log2 fold change IC90\": 0.05832844384142547, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.09105176399214367, \"functional effect\": 0.2832, \"times_seen\": 10.0}, {\"site\": 274, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 274, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00162155616650774, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.08734571731788358, \"functional effect\": 0.0198, \"times_seen\": 10.0}, {\"site\": 274, \"mutant\": \"P\", \"log2 fold change IC90\": -0.32631589355095425, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.06974271995771684, \"functional effect\": -2.5621, \"times_seen\": 3.0}, {\"site\": 274, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.006168380236443214, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": 0.08707087029205866, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 274, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": null, \"functional effect\": -3.0901, \"times_seen\": null}, {\"site\": 274, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"277\", \"IC90\": null, \"functional effect\": -0.9872, \"times_seen\": null}, {\"site\": 275, \"mutant\": \"E\", \"log2 fold change IC90\": -0.023505146508428863, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08603080737904875, \"functional effect\": -0.2369, \"times_seen\": 6.0}, {\"site\": 275, \"mutant\": \"I\", \"log2 fold change IC90\": 0.018621707496976662, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08857995296656249, \"functional effect\": -1.1404, \"times_seen\": 2.0}, {\"site\": 275, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 275, \"mutant\": \"L\", \"log2 fold change IC90\": 0.026775111554943106, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08908198064181054, \"functional effect\": -0.0428, \"times_seen\": 8.0}, {\"site\": 275, \"mutant\": \"N\", \"log2 fold change IC90\": 0.04483633604327647, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.09020421571469668, \"functional effect\": -0.1839, \"times_seen\": 13.0}, {\"site\": 275, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00019379270944831238, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.0874322018134274, \"functional effect\": -0.1017, \"times_seen\": 7.0}, {\"site\": 275, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01754954937359207, \"epitope\": \"all\", \"reference_site\": \"278\", \"IC90\": 0.08638668566247674, \"functional effect\": -2.2104, \"times_seen\": 1.0}, {\"site\": 276, \"mutant\": \"*\", \"log2 fold change IC90\": -0.008201976258318644, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.0869482232780364, \"functional effect\": -2.0079, \"times_seen\": 2.0}, {\"site\": 276, \"mutant\": \"C\", \"log2 fold change IC90\": -0.009560045047282154, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.08686641381395062, \"functional effect\": -1.7772, \"times_seen\": 2.0}, {\"site\": 276, \"mutant\": \"F\", \"log2 fold change IC90\": -0.026585823572774947, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.08584729640964853, \"functional effect\": 0.0871, \"times_seen\": 41.0}, {\"site\": 276, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": null, \"functional effect\": -1.0005, \"times_seen\": null}, {\"site\": 276, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02584172680149111, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.08589158516812874, \"functional effect\": -0.6036, \"times_seen\": 9.0}, {\"site\": 276, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": null, \"functional effect\": -2.5458, \"times_seen\": null}, {\"site\": 276, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"279\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 277, \"mutant\": \"D\", \"log2 fold change IC90\": 0.07615610731344923, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.09218388890266618, \"functional effect\": -0.0587, \"times_seen\": 13.0}, {\"site\": 277, \"mutant\": \"F\", \"log2 fold change IC90\": 0.008939470727322279, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08798746423053373, \"functional effect\": -2.2279, \"times_seen\": 4.0}, {\"site\": 277, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03112071862602717, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08935071303747366, \"functional effect\": -0.5216, \"times_seen\": 1.0}, {\"site\": 277, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005535488676054364, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08710907553045202, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 277, \"mutant\": \"K\", \"log2 fold change IC90\": -0.003957676997707346, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08720439498267865, \"functional effect\": -2.205, \"times_seen\": 1.0}, {\"site\": 277, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 277, \"mutant\": \"S\", \"log2 fold change IC90\": 0.17344760403794157, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.09861493307329453, \"functional effect\": -0.4854, \"times_seen\": 23.0}, {\"site\": 277, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011558078853947815, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": 0.08674619304916671, \"functional effect\": -0.5363, \"times_seen\": 7.0}, {\"site\": 277, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"280\", \"IC90\": null, \"functional effect\": -0.92, \"times_seen\": null}, {\"site\": 278, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": null, \"functional effect\": -1.0849, \"times_seen\": null}, {\"site\": 278, \"mutant\": \"A\", \"log2 fold change IC90\": 0.007752052132582091, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08791507542737681, \"functional effect\": -0.0399, \"times_seen\": 6.0}, {\"site\": 278, \"mutant\": \"D\", \"log2 fold change IC90\": 0.008233662661803367, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.0879444287507365, \"functional effect\": -0.022, \"times_seen\": 12.0}, {\"site\": 278, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 278, \"mutant\": \"G\", \"log2 fold change IC90\": -0.20642505309700918, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.07578611071614008, \"functional effect\": -0.0907, \"times_seen\": 20.0}, {\"site\": 278, \"mutant\": \"K\", \"log2 fold change IC90\": -0.11212908388951424, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08090503222174261, \"functional effect\": -0.0742, \"times_seen\": 66.0}, {\"site\": 278, \"mutant\": \"N\", \"log2 fold change IC90\": 0.004448792662475076, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08771401138599975, \"functional effect\": 0.1442, \"times_seen\": 5.0}, {\"site\": 278, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08904445109409022, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.08221001020147685, \"functional effect\": 0.0644, \"times_seen\": 35.0}, {\"site\": 278, \"mutant\": \"V\", \"log2 fold change IC90\": -0.014267925863443892, \"epitope\": \"all\", \"reference_site\": \"281\", \"IC90\": 0.0865834086244111, \"functional effect\": 0.1804, \"times_seen\": 3.0}, {\"site\": 279, \"mutant\": \"D\", \"log2 fold change IC90\": -0.003899963088039268, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08720788359746014, \"functional effect\": -0.3515, \"times_seen\": 3.0}, {\"site\": 279, \"mutant\": \"H\", \"log2 fold change IC90\": 0.008288561249758165, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08794777534629632, \"functional effect\": 0.3023, \"times_seen\": 5.0}, {\"site\": 279, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0015923129688776244, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08734748781954108, \"functional effect\": -0.158, \"times_seen\": 6.0}, {\"site\": 279, \"mutant\": \"K\", \"log2 fold change IC90\": 0.005692990444427992, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08778968964641734, \"functional effect\": -0.1816, \"times_seen\": 10.0}, {\"site\": 279, \"mutant\": \"L\", \"log2 fold change IC90\": 0.022660000229800845, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08882824722053843, \"functional effect\": -0.5737, \"times_seen\": 7.0}, {\"site\": 279, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 279, \"mutant\": \"S\", \"log2 fold change IC90\": -0.08048862338133025, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.082699000914059, \"functional effect\": -0.5124, \"times_seen\": 18.0}, {\"site\": 279, \"mutant\": \"T\", \"log2 fold change IC90\": 0.006129704915678829, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08781626825807663, \"functional effect\": -0.5122, \"times_seen\": 4.0}, {\"site\": 279, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008162074885542553, \"epitope\": \"all\", \"reference_site\": \"282\", \"IC90\": 0.08794006498035345, \"functional effect\": -0.3142, \"times_seen\": 6.0}, {\"site\": 280, \"mutant\": \"C\", \"log2 fold change IC90\": -0.008814306571895726, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.08691132723678387, \"functional effect\": -2.6094, \"times_seen\": 3.0}, {\"site\": 280, \"mutant\": \"D\", \"log2 fold change IC90\": -0.007869075003555916, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.08696828885780765, \"functional effect\": -2.9367, \"times_seen\": 3.0}, {\"site\": 280, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 280, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": null, \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 280, \"mutant\": \"R\", \"log2 fold change IC90\": -0.015844466235026458, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.0864888441603941, \"functional effect\": -2.1027, \"times_seen\": 1.0}, {\"site\": 280, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005295364211921422, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": 0.08712357531059797, \"functional effect\": -1.1641, \"times_seen\": 11.0}, {\"site\": 280, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": null, \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 280, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"283\", \"IC90\": null, \"functional effect\": -2.4582, \"times_seen\": null}, {\"site\": 281, \"mutant\": \"A\", \"log2 fold change IC90\": 0.14726438928431532, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.09684133133005886, \"functional effect\": -0.3641, \"times_seen\": 9.0}, {\"site\": 281, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03379375212149142, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08951641600200606, \"functional effect\": 0.0723, \"times_seen\": 35.0}, {\"site\": 281, \"mutant\": \"L\", \"log2 fold change IC90\": -0.011419107755324525, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08675454948905888, \"functional effect\": 0.0307, \"times_seen\": 10.0}, {\"site\": 281, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03632040088535051, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08526999209124425, \"functional effect\": -0.7634, \"times_seen\": 15.0}, {\"site\": 281, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0036498345865085768, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.08722300465054214, \"functional effect\": -2.1294, \"times_seen\": 1.0}, {\"site\": 281, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"284\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 282, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0012255425647986803, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.0873696966336633, \"functional effect\": -2.5283, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004095126493888495, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.0871960871775954, \"functional effect\": -0.9999, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 282, \"mutant\": \"L\", \"log2 fold change IC90\": 0.015278874905652344, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08837494417539632, \"functional effect\": 0.3094, \"times_seen\": 2.0}, {\"site\": 282, \"mutant\": \"M\", \"log2 fold change IC90\": -0.003591782366686105, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08722651446430846, \"functional effect\": 0.0603, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": null, \"functional effect\": -2.9946, \"times_seen\": null}, {\"site\": 282, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0005731460141378127, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.0874092147416954, \"functional effect\": -2.4581, \"times_seen\": 1.0}, {\"site\": 282, \"mutant\": \"V\", \"log2 fold change IC90\": -0.036870723757548136, \"epitope\": \"all\", \"reference_site\": \"285\", \"IC90\": 0.08523747165089461, \"functional effect\": -0.5039, \"times_seen\": 7.0}, {\"site\": 283, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0017780541801929598, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08733624290402626, \"functional effect\": 0.1206, \"times_seen\": 10.0}, {\"site\": 283, \"mutant\": \"I\", \"log2 fold change IC90\": -0.12734552961049786, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08005619204499068, \"functional effect\": -0.2387, \"times_seen\": 42.0}, {\"site\": 283, \"mutant\": \"K\", \"log2 fold change IC90\": -0.00524768764744023, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.0871264545201838, \"functional effect\": -0.5709, \"times_seen\": 2.0}, {\"site\": 283, \"mutant\": \"N\", \"log2 fold change IC90\": -0.017118497844846314, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08641250031859532, \"functional effect\": 0.375, \"times_seen\": 6.0}, {\"site\": 283, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": null, \"functional effect\": 0.3002, \"times_seen\": null}, {\"site\": 283, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01933229014484813, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.0862800034120504, \"functional effect\": 0.0237, \"times_seen\": 5.0}, {\"site\": 283, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 283, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.013959675101643587, \"epitope\": \"all\", \"reference_site\": \"286\", \"IC90\": 0.08829417109467098, \"functional effect\": -0.7594, \"times_seen\": 5.0}, {\"site\": 284, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02610031599469702, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08587619130824845, \"functional effect\": 0.0436, \"times_seen\": 17.0}, {\"site\": 284, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 284, \"mutant\": \"E\", \"log2 fold change IC90\": -0.019495680808407873, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08627023242902825, \"functional effect\": 0.0117, \"times_seen\": 19.0}, {\"site\": 284, \"mutant\": \"G\", \"log2 fold change IC90\": -0.002521829163283415, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08729122869860502, \"functional effect\": -0.256, \"times_seen\": 37.0}, {\"site\": 284, \"mutant\": \"H\", \"log2 fold change IC90\": -0.7955476626523509, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.050378594074120514, \"functional effect\": -0.5928, \"times_seen\": 21.0}, {\"site\": 284, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": null, \"functional effect\": -0.7471, \"times_seen\": null}, {\"site\": 284, \"mutant\": \"N\", \"log2 fold change IC90\": 0.2686168229044971, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.10533955366133974, \"functional effect\": -0.2422, \"times_seen\": 42.0}, {\"site\": 284, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.004025058427371896, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08768825267000144, \"functional effect\": -0.1861, \"times_seen\": 5.0}, {\"site\": 284, \"mutant\": \"R\", \"log2 fold change IC90\": 0.023779131909609827, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08889718006510083, \"functional effect\": -0.6825, \"times_seen\": 2.0}, {\"site\": 284, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011416909538278648, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08675468167602104, \"functional effect\": -2.4039, \"times_seen\": 2.0}, {\"site\": 284, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.041020058072281575, \"epitope\": \"all\", \"reference_site\": \"287\", \"IC90\": 0.08996591902142337, \"functional effect\": -1.7855, \"times_seen\": 7.0}, {\"site\": 285, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 285, \"mutant\": \"C\", \"log2 fold change IC90\": 0.03039081184839984, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.0893055190123467, \"functional effect\": -0.3032, \"times_seen\": 10.0}, {\"site\": 285, \"mutant\": \"D\", \"log2 fold change IC90\": -0.00043263698869246104, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08741772823992763, \"functional effect\": -1.3855, \"times_seen\": 1.0}, {\"site\": 285, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0015852150668499564, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08734791756069805, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 285, \"mutant\": \"K\", \"log2 fold change IC90\": -0.005797523358651811, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08709325546762114, \"functional effect\": -2.0516, \"times_seen\": 1.0}, {\"site\": 285, \"mutant\": \"S\", \"log2 fold change IC90\": -0.010430314881621227, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.0868140296156744, \"functional effect\": -0.4047, \"times_seen\": 30.0}, {\"site\": 285, \"mutant\": \"T\", \"log2 fold change IC90\": -0.19803204329708038, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.07622828827478144, \"functional effect\": -0.6318, \"times_seen\": 42.0}, {\"site\": 285, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02985995687325108, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08565269063306712, \"functional effect\": 0.0028, \"times_seen\": 20.0}, {\"site\": 285, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.031098800949611736, \"epitope\": \"all\", \"reference_site\": \"288\", \"IC90\": 0.08934935561606128, \"functional effect\": -2.377, \"times_seen\": 1.0}, {\"site\": 286, \"mutant\": \"A\", \"log2 fold change IC90\": -0.028617080217711005, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08572651191576451, \"functional effect\": -0.9491, \"times_seen\": 11.0}, {\"site\": 286, \"mutant\": \"C\", \"log2 fold change IC90\": 0.02818319959533854, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08916896819018397, \"functional effect\": -0.7449, \"times_seen\": 5.0}, {\"site\": 286, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": null, \"functional effect\": -3.2617, \"times_seen\": null}, {\"site\": 286, \"mutant\": \"I\", \"log2 fold change IC90\": 0.008842748625320147, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08798156551529747, \"functional effect\": 0.0764, \"times_seen\": 46.0}, {\"site\": 286, \"mutant\": \"L\", \"log2 fold change IC90\": 0.11547359012797753, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.09473070451093432, \"functional effect\": -0.3648, \"times_seen\": 35.0}, {\"site\": 286, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013779544287848007, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08661272382854275, \"functional effect\": -2.4112, \"times_seen\": 4.0}, {\"site\": 286, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.020841017615293726, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08618982151927078, \"functional effect\": -1.5933, \"times_seen\": 3.0}, {\"site\": 286, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0054211541447325064, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.08711597925556665, \"functional effect\": -2.7813, \"times_seen\": 1.0}, {\"site\": 286, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": null, \"functional effect\": -2.3127, \"times_seen\": null}, {\"site\": 286, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"289\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0031243586778658813, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08725477985900304, \"functional effect\": -2.8712, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0038531942908634595, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08721071071879533, \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": null, \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02442254968545968, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08597611817232717, \"functional effect\": -2.6977, \"times_seen\": 5.0}, {\"site\": 287, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00021027322203847913, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08743120304429615, \"functional effect\": -2.4834, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0017694247978478615, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": 0.08755126042727514, \"functional effect\": -1.8107, \"times_seen\": 1.0}, {\"site\": 287, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": null, \"functional effect\": -1.8474, \"times_seen\": null}, {\"site\": 287, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"290\", \"IC90\": null, \"functional effect\": -1.9768, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": -2.8456, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06551283346609146, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.08356192281952755, \"functional effect\": -2.8773, \"times_seen\": 2.0}, {\"site\": 288, \"mutant\": \"R\", \"log2 fold change IC90\": -1.9316449562628306, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.022921692391665107, \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 288, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": -2.9996, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": null, \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 288, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07269367254033161, \"epitope\": \"all\", \"reference_site\": \"291\", \"IC90\": 0.0831470368919627, \"functional effect\": -2.942, \"times_seen\": 4.0}, {\"site\": 289, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 289, \"mutant\": \"C\", \"log2 fold change IC90\": -0.050450132728933415, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.084438935491458, \"functional effect\": -0.5923, \"times_seen\": 6.0}, {\"site\": 289, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": null, \"functional effect\": -2.9013, \"times_seen\": null}, {\"site\": 289, \"mutant\": \"G\", \"log2 fold change IC90\": -0.02971142802609882, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.0856615092329317, \"functional effect\": 0.0892, \"times_seen\": 21.0}, {\"site\": 289, \"mutant\": \"R\", \"log2 fold change IC90\": -0.051388750371141725, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08438401737228275, \"functional effect\": -1.2288, \"times_seen\": 4.0}, {\"site\": 289, \"mutant\": \"S\", \"log2 fold change IC90\": -0.021730639566410193, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08613668990166741, \"functional effect\": -0.0029, \"times_seen\": 65.0}, {\"site\": 289, \"mutant\": \"T\", \"log2 fold change IC90\": -3.7109070269053497, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.006677831041617856, \"functional effect\": -0.4092, \"times_seen\": 99.0}, {\"site\": 289, \"mutant\": \"V\", \"log2 fold change IC90\": -0.06984609233521688, \"epitope\": \"all\", \"reference_site\": \"292\", \"IC90\": 0.08331131393509017, \"functional effect\": -1.2201, \"times_seen\": 29.0}, {\"site\": 290, \"mutant\": \"F\", \"log2 fold change IC90\": 0.007098657841712286, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08787526784453178, \"functional effect\": -0.1435, \"times_seen\": 20.0}, {\"site\": 290, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 290, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0751101933454818, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.09211708235442083, \"functional effect\": -0.566, \"times_seen\": 18.0}, {\"site\": 290, \"mutant\": \"P\", \"log2 fold change IC90\": -0.014800030397307868, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.0865514802349467, \"functional effect\": -2.7275, \"times_seen\": 5.0}, {\"site\": 290, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.023512201522077482, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08888073364852563, \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 290, \"mutant\": \"R\", \"log2 fold change IC90\": 0.01889999184659207, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.08859704097995996, \"functional effect\": -1.4644, \"times_seen\": 2.0}, {\"site\": 290, \"mutant\": \"T\", \"log2 fold change IC90\": 0.01255092192587762, \"epitope\": \"all\", \"reference_site\": \"293\", \"IC90\": 0.0882079962753198, \"functional effect\": -0.4162, \"times_seen\": 4.0}, {\"site\": 291, \"mutant\": \"C\", \"log2 fold change IC90\": 0.010077260505933784, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08805688342283823, \"functional effect\": -0.4328, \"times_seen\": 12.0}, {\"site\": 291, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 291, \"mutant\": \"E\", \"log2 fold change IC90\": -0.021250047098575874, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08616538864881454, \"functional effect\": -1.797, \"times_seen\": 6.0}, {\"site\": 291, \"mutant\": \"G\", \"log2 fold change IC90\": 7.549156658844444e-05, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08744852287500626, \"functional effect\": -0.8142, \"times_seen\": 5.0}, {\"site\": 291, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": null, \"functional effect\": -2.6269, \"times_seen\": null}, {\"site\": 291, \"mutant\": \"N\", \"log2 fold change IC90\": -0.09352726593356125, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": 0.08195495956720102, \"functional effect\": -0.7427, \"times_seen\": 15.0}, {\"site\": 291, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"294\", \"IC90\": null, \"functional effect\": -3.032, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -3.0221, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -2.9899, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -2.4632, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": null, \"functional effect\": -3.2361, \"times_seen\": null}, {\"site\": 292, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01636651129776419, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": 0.08645755348237011, \"functional effect\": -2.5027, \"times_seen\": 4.0}, {\"site\": 292, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0053830044491139685, \"epitope\": \"all\", \"reference_site\": \"295\", \"IC90\": 0.08711828292469967, \"functional effect\": -1.8602, \"times_seen\": 1.0}, {\"site\": 293, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0074789499138178455, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.08789843467579948, \"functional effect\": -0.0809, \"times_seen\": 7.0}, {\"site\": 293, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 293, \"mutant\": \"M\", \"log2 fold change IC90\": -0.002736880133262324, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.08727821786551875, \"functional effect\": -1.0336, \"times_seen\": 6.0}, {\"site\": 293, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004520713182969103, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.08717036863002557, \"functional effect\": -1.3293, \"times_seen\": 1.0}, {\"site\": 293, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0031944308063782422, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": 0.08725054197123452, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 293, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": null, \"functional effect\": -3.268, \"times_seen\": null}, {\"site\": 293, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"296\", \"IC90\": null, \"functional effect\": -2.318, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -2.9573, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"L\", \"log2 fold change IC90\": 0.008658773254165903, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": 0.08797034664457859, \"functional effect\": -2.9686, \"times_seen\": 4.0}, {\"site\": 294, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -1.8098, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 294, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"297\", \"IC90\": null, \"functional effect\": -3.128, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -2.5392, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -1.1533, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -2.9724, \"times_seen\": null}, {\"site\": 295, \"mutant\": \"K\", \"log2 fold change IC90\": 0.02725006518241166, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.08911131239514558, \"functional effect\": -2.4414, \"times_seen\": 3.0}, {\"site\": 295, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0034734769663816926, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.0872336675982278, \"functional effect\": -2.3102, \"times_seen\": 1.0}, {\"site\": 295, \"mutant\": \"R\", \"log2 fold change IC90\": 0.012898175834008459, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": 0.08822923032494373, \"functional effect\": -2.7989, \"times_seen\": 4.0}, {\"site\": 295, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"298\", \"IC90\": null, \"functional effect\": -2.5601, \"times_seen\": null}, {\"site\": 296, \"mutant\": \"A\", \"log2 fold change IC90\": -0.1688423927050866, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.07778630247975732, \"functional effect\": -0.5588, \"times_seen\": 44.0}, {\"site\": 296, \"mutant\": \"I\", \"log2 fold change IC90\": -2.063227448150531, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.020923599715721004, \"functional effect\": -0.0909, \"times_seen\": 46.0}, {\"site\": 296, \"mutant\": \"K\", \"log2 fold change IC90\": -0.05015561982958131, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.08445617468165446, \"functional effect\": -2.6088, \"times_seen\": 1.0}, {\"site\": 296, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0533319392784567, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.08427043570617992, \"functional effect\": -2.7361, \"times_seen\": 2.0}, {\"site\": 296, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"299\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": -1.2613, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"M\", \"log2 fold change IC90\": -0.023046591987556004, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": 0.08605815625367756, \"functional effect\": -0.957, \"times_seen\": 8.0}, {\"site\": 297, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": -2.7906, \"times_seen\": null}, {\"site\": 297, \"mutant\": \"R\", \"log2 fold change IC90\": -0.7600068122169176, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": 0.05163508608888681, \"functional effect\": -0.3747, \"times_seen\": 19.0}, {\"site\": 297, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"300\", \"IC90\": null, \"functional effect\": -1.4359, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"E\", \"log2 fold change IC90\": -0.4170346828073737, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.06549223387981468, \"functional effect\": -1.8786, \"times_seen\": 2.0}, {\"site\": 298, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": null, \"functional effect\": -2.6362, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01192288986201026, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.08672426051009878, \"functional effect\": -1.2026, \"times_seen\": 1.0}, {\"site\": 298, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": null, \"functional effect\": -2.7258, \"times_seen\": null}, {\"site\": 298, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01709742030276032, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.08641376280052364, \"functional effect\": -2.9714, \"times_seen\": 1.0}, {\"site\": 298, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.034824167022144144, \"epitope\": \"all\", \"reference_site\": \"301\", \"IC90\": 0.08535847235089933, \"functional effect\": -1.9379, \"times_seen\": 4.0}, {\"site\": 299, \"mutant\": \"A\", \"log2 fold change IC90\": 0.019791447430892055, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08865180288811488, \"functional effect\": -1.499, \"times_seen\": 2.0}, {\"site\": 299, \"mutant\": \"I\", \"log2 fold change IC90\": -0.016468777154097825, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08645142513082765, \"functional effect\": -1.3649, \"times_seen\": 2.0}, {\"site\": 299, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00010403184669112458, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08743764179470637, \"functional effect\": -2.7225, \"times_seen\": 1.0}, {\"site\": 299, \"mutant\": \"S\", \"log2 fold change IC90\": -0.038251160078262486, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.08515595156327976, \"functional effect\": -0.1582, \"times_seen\": 10.0}, {\"site\": 299, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 299, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"302\", \"IC90\": null, \"functional effect\": -2.4022, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0003678485733694, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08742165407532365, \"functional effect\": -1.4017, \"times_seen\": 8.0}, {\"site\": 300, \"mutant\": \"I\", \"log2 fold change IC90\": -0.09621055293464444, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08180267215184416, \"functional effect\": -0.2625, \"times_seen\": 11.0}, {\"site\": 300, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"M\", \"log2 fold change IC90\": 1.1964261983794113, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.20039640494019567, \"functional effect\": -0.3669, \"times_seen\": 11.0}, {\"site\": 300, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0253687989154314, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08899518747159836, \"functional effect\": -2.7576, \"times_seen\": 6.0}, {\"site\": 300, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": null, \"functional effect\": -0.1477, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": null, \"functional effect\": -0.6929, \"times_seen\": null}, {\"site\": 300, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0016135624581144175, \"epitope\": \"all\", \"reference_site\": \"303\", \"IC90\": 0.08734620128581042, \"functional effect\": -0.479, \"times_seen\": 3.0}, {\"site\": 301, \"mutant\": \"E\", \"log2 fold change IC90\": -0.023417274645831907, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08603604751455816, \"functional effect\": 0.4159, \"times_seen\": 7.0}, {\"site\": 301, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": null, \"functional effect\": -3.2048, \"times_seen\": null}, {\"site\": 301, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 301, \"mutant\": \"N\", \"log2 fold change IC90\": -0.021600114018245922, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08614448333476393, \"functional effect\": 0.2879, \"times_seen\": 6.0}, {\"site\": 301, \"mutant\": \"R\", \"log2 fold change IC90\": 0.040324499515012664, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08992255470627519, \"functional effect\": 0.0628, \"times_seen\": 6.0}, {\"site\": 301, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004999987118848402, \"epitope\": \"all\", \"reference_site\": \"304\", \"IC90\": 0.08714141480008279, \"functional effect\": 0.158, \"times_seen\": 1.0}, {\"site\": 302, \"mutant\": \"A\", \"log2 fold change IC90\": -0.016077014209427663, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08647490414948146, \"functional effect\": -0.1786, \"times_seen\": 3.0}, {\"site\": 302, \"mutant\": \"C\", \"log2 fold change IC90\": 0.011880480288340923, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08816701424329185, \"functional effect\": -1.4452, \"times_seen\": 1.0}, {\"site\": 302, \"mutant\": \"F\", \"log2 fold change IC90\": -0.005333279621154581, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08712128564957383, \"functional effect\": -2.3834, \"times_seen\": 1.0}, {\"site\": 302, \"mutant\": \"I\", \"log2 fold change IC90\": -0.013144487182780436, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.08665085810635682, \"functional effect\": -1.1237, \"times_seen\": 4.0}, {\"site\": 302, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": null, \"functional effect\": -1.1989, \"times_seen\": null}, {\"site\": 302, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": null, \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 302, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 302, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02616590216680884, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": 0.0858722873905934, \"functional effect\": -0.0342, \"times_seen\": 6.0}, {\"site\": 302, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"305\", \"IC90\": null, \"functional effect\": -2.6361, \"times_seen\": null}, {\"site\": 303, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 303, \"mutant\": \"I\", \"log2 fold change IC90\": 0.011667322910011192, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.08815398857897178, \"functional effect\": -0.6279, \"times_seen\": 1.0}, {\"site\": 303, \"mutant\": \"L\", \"log2 fold change IC90\": -0.481356544794893, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.06263642961697558, \"functional effect\": 0.0613, \"times_seen\": 24.0}, {\"site\": 303, \"mutant\": \"S\", \"log2 fold change IC90\": 1.908904168551638, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.32837279262465163, \"functional effect\": -1.6708, \"times_seen\": 9.0}, {\"site\": 303, \"mutant\": \"V\", \"log2 fold change IC90\": 0.020646387785427253, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": 0.08870435347103844, \"functional effect\": -0.909, \"times_seen\": 4.0}, {\"site\": 303, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"306\", \"IC90\": null, \"functional effect\": -2.4926, \"times_seen\": null}, {\"site\": 304, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": null, \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 304, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05529223888110659, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.09086034369049371, \"functional effect\": -0.3108, \"times_seen\": 39.0}, {\"site\": 304, \"mutant\": \"C\", \"log2 fold change IC90\": -0.024497707973313444, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08597163929817754, \"functional effect\": -1.2485, \"times_seen\": 14.0}, {\"site\": 304, \"mutant\": \"D\", \"log2 fold change IC90\": -0.3376245715726686, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.06919817321178308, \"functional effect\": -0.0379, \"times_seen\": 21.0}, {\"site\": 304, \"mutant\": \"E\", \"log2 fold change IC90\": -0.048314545987532695, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08456402097277899, \"functional effect\": -0.1194, \"times_seen\": 21.0}, {\"site\": 304, \"mutant\": \"F\", \"log2 fold change IC90\": -0.006643979949615477, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08704217118743492, \"functional effect\": -0.0637, \"times_seen\": 20.0}, {\"site\": 304, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03148094581316463, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08555650669321332, \"functional effect\": -0.2287, \"times_seen\": 20.0}, {\"site\": 304, \"mutant\": \"H\", \"log2 fold change IC90\": 0.25615571327286507, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.10443361369796826, \"functional effect\": -0.1652, \"times_seen\": 56.0}, {\"site\": 304, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04704406469977353, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08463852343051276, \"functional effect\": -0.1408, \"times_seen\": 65.0}, {\"site\": 304, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02401211884991825, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08600058090971148, \"functional effect\": -0.6245, \"times_seen\": 25.0}, {\"site\": 304, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05859579206474826, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08396352475341345, \"functional effect\": -0.5884, \"times_seen\": 31.0}, {\"site\": 304, \"mutant\": \"M\", \"log2 fold change IC90\": 0.041339891699505034, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08998586593682878, \"functional effect\": -0.2332, \"times_seen\": 14.0}, {\"site\": 304, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0043544716109296415, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08770827697428146, \"functional effect\": -0.3637, \"times_seen\": 43.0}, {\"site\": 304, \"mutant\": \"P\", \"log2 fold change IC90\": 0.009490583444693581, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08802108205838269, \"functional effect\": -2.9172, \"times_seen\": 5.0}, {\"site\": 304, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.034434397440702605, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08538153656735549, \"functional effect\": -0.1465, \"times_seen\": 13.0}, {\"site\": 304, \"mutant\": \"R\", \"log2 fold change IC90\": -0.025184680128482333, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08593071168598097, \"functional effect\": -0.4913, \"times_seen\": 48.0}, {\"site\": 304, \"mutant\": \"S\", \"log2 fold change IC90\": -0.5306119065634932, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.06053403909375077, \"functional effect\": -0.1091, \"times_seen\": 45.0}, {\"site\": 304, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 304, \"mutant\": \"V\", \"log2 fold change IC90\": 0.10001436342060294, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.0937210350358778, \"functional effect\": -0.151, \"times_seen\": 28.0}, {\"site\": 304, \"mutant\": \"W\", \"log2 fold change IC90\": 0.011014957271488273, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.0881141356432539, \"functional effect\": -0.1403, \"times_seen\": 7.0}, {\"site\": 304, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02251819520267074, \"epitope\": \"all\", \"reference_site\": \"307\", \"IC90\": 0.08881951656533099, \"functional effect\": -0.1142, \"times_seen\": 29.0}, {\"site\": 305, \"mutant\": \"A\", \"log2 fold change IC90\": -0.009997621587570057, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08684007079625654, \"functional effect\": -3.0197, \"times_seen\": 1.0}, {\"site\": 305, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006885823109105772, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08702758127840483, \"functional effect\": -2.9654, \"times_seen\": 1.0}, {\"site\": 305, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": null, \"functional effect\": -2.9941, \"times_seen\": null}, {\"site\": 305, \"mutant\": \"I\", \"log2 fold change IC90\": -0.040661521269922195, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08501379731319562, \"functional effect\": -0.2195, \"times_seen\": 20.0}, {\"site\": 305, \"mutant\": \"L\", \"log2 fold change IC90\": -0.6056032730569563, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.05746785696629681, \"functional effect\": -0.2644, \"times_seen\": 38.0}, {\"site\": 305, \"mutant\": \"M\", \"log2 fold change IC90\": -0.025681783308838663, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.08590110801341229, \"functional effect\": -1.6965, \"times_seen\": 6.0}, {\"site\": 305, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"308\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 306, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": null, \"functional effect\": -3.0868, \"times_seen\": null}, {\"site\": 306, \"mutant\": \"A\", \"log2 fold change IC90\": -0.009218481787733051, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.08688698218576037, \"functional effect\": 0.0088, \"times_seen\": 6.0}, {\"site\": 306, \"mutant\": \"D\", \"log2 fold change IC90\": -0.9543352345313852, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.045128013985744925, \"functional effect\": 0.2651, \"times_seen\": 15.0}, {\"site\": 306, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 306, \"mutant\": \"G\", \"log2 fold change IC90\": 0.027181171643244233, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.0891070571319503, \"functional effect\": -0.2689, \"times_seen\": 12.0}, {\"site\": 306, \"mutant\": \"K\", \"log2 fold change IC90\": 0.1540899400392716, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.09730058397434174, \"functional effect\": -0.3164, \"times_seen\": 43.0}, {\"site\": 306, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014482505034481568, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.0865705316033379, \"functional effect\": -0.3346, \"times_seen\": 10.0}, {\"site\": 306, \"mutant\": \"R\", \"log2 fold change IC90\": -0.024002112073991135, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.08600117742630228, \"functional effect\": -0.4373, \"times_seen\": 5.0}, {\"site\": 306, \"mutant\": \"V\", \"log2 fold change IC90\": -0.008211162208464925, \"epitope\": \"all\", \"reference_site\": \"309\", \"IC90\": 0.08694766966172876, \"functional effect\": -0.4553, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": null, \"functional effect\": -2.9005, \"times_seen\": null}, {\"site\": 307, \"mutant\": \"E\", \"log2 fold change IC90\": 0.011139033387723063, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.08812171405003359, \"functional effect\": -1.2932, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 307, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": null, \"functional effect\": -2.8108, \"times_seen\": null}, {\"site\": 307, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01202557100202093, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.08817588157694874, \"functional effect\": -3.1432, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.006240322178588115, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.0878230017446233, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 307, \"mutant\": \"R\", \"log2 fold change IC90\": 1.2646151965164236, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.21009555298275512, \"functional effect\": -0.8163, \"times_seen\": 50.0}, {\"site\": 307, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0016592793003713411, \"epitope\": \"all\", \"reference_site\": \"310\", \"IC90\": 0.08734343345953786, \"functional effect\": -2.4752, \"times_seen\": 4.0}, {\"site\": 308, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": null, \"functional effect\": -2.4876, \"times_seen\": null}, {\"site\": 308, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0008458214835882443, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.08739269559126232, \"functional effect\": -2.7756, \"times_seen\": 1.0}, {\"site\": 308, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 308, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005747600233725158, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.08709626930116136, \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 308, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005649359375524453, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": 0.08710220035611918, \"functional effect\": -2.9695, \"times_seen\": 2.0}, {\"site\": 308, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": null, \"functional effect\": -1.6802, \"times_seen\": null}, {\"site\": 308, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"311\", \"IC90\": null, \"functional effect\": -3.1353, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005115627749499521, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.08713443017476762, \"functional effect\": -1.3805, \"times_seen\": 1.0}, {\"site\": 309, \"mutant\": \"M\", \"log2 fold change IC90\": 0.017523359092636626, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.08851254119779696, \"functional effect\": -0.8374, \"times_seen\": 2.0}, {\"site\": 309, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": null, \"functional effect\": -0.0493, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": null, \"functional effect\": -1.8036, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": null, \"functional effect\": -2.144, \"times_seen\": null}, {\"site\": 309, \"mutant\": \"V\", \"log2 fold change IC90\": -0.06063204040129906, \"epitope\": \"all\", \"reference_site\": \"312\", \"IC90\": 0.08384510056543377, \"functional effect\": -0.7195, \"times_seen\": 30.0}, {\"site\": 310, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.7744, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -0.4934, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.4895, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"H\", \"log2 fold change IC90\": 0.04267680270036885, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": 0.09006929233596679, \"functional effect\": -1.1574, \"times_seen\": 18.0}, {\"site\": 310, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0023839830484351553, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": 0.08729956956848013, \"functional effect\": -1.9558, \"times_seen\": 1.0}, {\"site\": 310, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.942, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.6642, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -2.0463, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": null, \"functional effect\": -3.0359, \"times_seen\": null}, {\"site\": 310, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"313\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": null, \"functional effect\": -1.2648, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": null, \"functional effect\": -0.3253, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"H\", \"log2 fold change IC90\": 0.04822500030435079, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.09041634028856634, \"functional effect\": 0.176, \"times_seen\": 23.0}, {\"site\": 311, \"mutant\": \"K\", \"log2 fold change IC90\": 1.608438379718001, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.2666354878178, \"functional effect\": -0.7858, \"times_seen\": 67.0}, {\"site\": 311, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03821577113411818, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.08515804044283469, \"functional effect\": -1.0693, \"times_seen\": 16.0}, {\"site\": 311, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0027455126452915757, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.08727769562901681, \"functional effect\": -2.9646, \"times_seen\": 1.0}, {\"site\": 311, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 311, \"mutant\": \"R\", \"log2 fold change IC90\": -0.013995327671179437, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.08659977016305566, \"functional effect\": -0.3635, \"times_seen\": 15.0}, {\"site\": 311, \"mutant\": \"T\", \"log2 fold change IC90\": -0.9292231054447452, \"epitope\": \"all\", \"reference_site\": \"314\", \"IC90\": 0.045920406660751055, \"functional effect\": -0.4081, \"times_seen\": 6.0}, {\"site\": 312, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": null, \"functional effect\": -2.5656, \"times_seen\": null}, {\"site\": 312, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": null, \"functional effect\": -2.5653, \"times_seen\": null}, {\"site\": 312, \"mutant\": \"I\", \"log2 fold change IC90\": 0.032088801312317325, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.08941068961169182, \"functional effect\": -0.6353, \"times_seen\": 53.0}, {\"site\": 312, \"mutant\": \"L\", \"log2 fold change IC90\": 0.018377574757252643, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.08856496474217704, \"functional effect\": -0.189, \"times_seen\": 6.0}, {\"site\": 312, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02555488814515698, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.08590866395160562, \"functional effect\": -1.8127, \"times_seen\": 2.0}, {\"site\": 312, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": null, \"functional effect\": -2.99, \"times_seen\": null}, {\"site\": 312, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"315\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"A\", \"log2 fold change IC90\": 0.9809060328417802, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.17258851486772803, \"functional effect\": -0.3363, \"times_seen\": 6.0}, {\"site\": 313, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": null, \"functional effect\": -0.2211, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0038738682930576245, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08720946098724768, \"functional effect\": -1.5098, \"times_seen\": 17.0}, {\"site\": 313, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": null, \"functional effect\": -0.8517, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005751951957632244, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08709600658566366, \"functional effect\": -0.2965, \"times_seen\": 1.0}, {\"site\": 313, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04230985207646588, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08491672146879624, \"functional effect\": -2.2771, \"times_seen\": 1.0}, {\"site\": 313, \"mutant\": \"N\", \"log2 fold change IC90\": -0.11948765169291205, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.08049342101735181, \"functional effect\": -0.6941, \"times_seen\": 34.0}, {\"site\": 313, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": null, \"functional effect\": -2.6799, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 313, \"mutant\": \"T\", \"log2 fold change IC90\": -0.4522796923720502, \"epitope\": \"all\", \"reference_site\": \"316\", \"IC90\": 0.06391164546213275, \"functional effect\": -0.7144, \"times_seen\": 14.0}, {\"site\": 314, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0296169573307334, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.08566711871177284, \"functional effect\": -0.6442, \"times_seen\": 6.0}, {\"site\": 314, \"mutant\": \"I\", \"log2 fold change IC90\": 0.016975051714035974, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.08847890771550522, \"functional effect\": -0.6906, \"times_seen\": 15.0}, {\"site\": 314, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": null, \"functional effect\": -2.3119, \"times_seen\": null}, {\"site\": 314, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 314, \"mutant\": \"S\", \"log2 fold change IC90\": 0.11712075141859762, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.09483892270988362, \"functional effect\": 0.397, \"times_seen\": 5.0}, {\"site\": 314, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0039475122385106065, \"epitope\": \"all\", \"reference_site\": \"317\", \"IC90\": 0.0872050093985971, \"functional effect\": -1.267, \"times_seen\": 13.0}, {\"site\": 315, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0038876187379921524, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08720862979067291, \"functional effect\": -3.0955, \"times_seen\": 1.0}, {\"site\": 315, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 315, \"mutant\": \"I\", \"log2 fold change IC90\": 0.021932446309998542, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08878346225593008, \"functional effect\": -2.3483, \"times_seen\": 3.0}, {\"site\": 315, \"mutant\": \"L\", \"log2 fold change IC90\": -0.02515290608146072, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08593260425264508, \"functional effect\": -2.7033, \"times_seen\": 2.0}, {\"site\": 315, \"mutant\": \"S\", \"log2 fold change IC90\": 0.010851255829461285, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.0881041379706157, \"functional effect\": -1.9318, \"times_seen\": 5.0}, {\"site\": 315, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004066965820690757, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08719778921746575, \"functional effect\": -3.0863, \"times_seen\": 1.0}, {\"site\": 315, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0014507520172999636, \"epitope\": \"all\", \"reference_site\": \"318\", \"IC90\": 0.08753192361551732, \"functional effect\": -0.6018, \"times_seen\": 6.0}, {\"site\": 316, \"mutant\": \"E\", \"log2 fold change IC90\": -1.2870268257493318, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.03583406466337139, \"functional effect\": -2.9537, \"times_seen\": 2.0}, {\"site\": 316, \"mutant\": \"G\", \"log2 fold change IC90\": -0.02299104328545674, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.08606146985134158, \"functional effect\": -2.6552, \"times_seen\": 3.0}, {\"site\": 316, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014161285823844402, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.08658980886778865, \"functional effect\": -2.9195, \"times_seen\": 3.0}, {\"site\": 316, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -3.1273, \"times_seen\": null}, {\"site\": 316, \"mutant\": \"T\", \"log2 fold change IC90\": 0.007460502698862316, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": 0.08789731075778068, \"functional effect\": -2.8689, \"times_seen\": 2.0}, {\"site\": 316, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"319\", \"IC90\": null, \"functional effect\": -2.9726, \"times_seen\": null}, {\"site\": 317, \"mutant\": \"A\", \"log2 fold change IC90\": -0.038014535804946986, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.08516991960027244, \"functional effect\": -0.7064, \"times_seen\": 10.0}, {\"site\": 317, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": null, \"functional effect\": -1.9108, \"times_seen\": null}, {\"site\": 317, \"mutant\": \"F\", \"log2 fold change IC90\": 0.06574996692970124, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.0915213600012051, \"functional effect\": -0.8559, \"times_seen\": 34.0}, {\"site\": 317, \"mutant\": \"I\", \"log2 fold change IC90\": 0.6522018140285848, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.13742383440431705, \"functional effect\": -0.9803, \"times_seen\": 40.0}, {\"site\": 317, \"mutant\": \"L\", \"log2 fold change IC90\": 0.003980115936001555, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.08768552106904323, \"functional effect\": -1.5735, \"times_seen\": 1.0}, {\"site\": 317, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0022252852072446845, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.08757892910186317, \"functional effect\": -0.7449, \"times_seen\": 1.0}, {\"site\": 317, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"320\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 318, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0057786731515354845, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08709439343273705, \"functional effect\": -2.6762, \"times_seen\": 1.0}, {\"site\": 318, \"mutant\": \"E\", \"log2 fold change IC90\": 0.013608095266252253, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08827265672947411, \"functional effect\": -0.9377, \"times_seen\": 1.0}, {\"site\": 318, \"mutant\": \"H\", \"log2 fold change IC90\": -0.029228849075558685, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08569016764974492, \"functional effect\": -0.5327, \"times_seen\": 10.0}, {\"site\": 318, \"mutant\": \"K\", \"log2 fold change IC90\": 0.010330126400122295, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08807231879442927, \"functional effect\": -0.8911, \"times_seen\": 9.0}, {\"site\": 318, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05486431169125731, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08418097457183647, \"functional effect\": -0.0811, \"times_seen\": 12.0}, {\"site\": 318, \"mutant\": \"N\", \"log2 fold change IC90\": -0.022592131466423183, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08608526953407603, \"functional effect\": -0.9701, \"times_seen\": 6.0}, {\"site\": 318, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0028226895007178367, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.0876152020915472, \"functional effect\": -1.0749, \"times_seen\": 5.0}, {\"site\": 318, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 318, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0042302882651798854, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.0877007276043757, \"functional effect\": -0.2258, \"times_seen\": 8.0}, {\"site\": 318, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01052110962701561, \"epitope\": \"all\", \"reference_site\": \"321\", \"IC90\": 0.08680856622288109, \"functional effect\": -0.4794, \"times_seen\": 2.0}, {\"site\": 319, \"mutant\": \"A\", \"log2 fold change IC90\": 0.04735524521191169, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.09036184757171525, \"functional effect\": -0.2729, \"times_seen\": 4.0}, {\"site\": 319, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -2.9236, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -2.8881, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -2.8281, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": null, \"functional effect\": -3.13, \"times_seen\": null}, {\"site\": 319, \"mutant\": \"S\", \"log2 fold change IC90\": 0.030678118171290524, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.0893233055816258, \"functional effect\": -1.9086, \"times_seen\": 5.0}, {\"site\": 319, \"mutant\": \"T\", \"log2 fold change IC90\": -0.018870559464145276, \"epitope\": \"all\", \"reference_site\": \"322\", \"IC90\": 0.08630762151518369, \"functional effect\": -2.2576, \"times_seen\": 4.0}, {\"site\": 320, \"mutant\": \"A\", \"log2 fold change IC90\": -0.1514320926244876, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.0787307068591849, \"functional effect\": -0.3162, \"times_seen\": 10.0}, {\"site\": 320, \"mutant\": \"C\", \"log2 fold change IC90\": 0.00026584776393085796, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08746006201949319, \"functional effect\": -0.7671, \"times_seen\": 3.0}, {\"site\": 320, \"mutant\": \"I\", \"log2 fold change IC90\": 1.1466270185480365, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.1935971141604393, \"functional effect\": -0.4383, \"times_seen\": 60.0}, {\"site\": 320, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03712435608516003, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08522248783416546, \"functional effect\": -0.5786, \"times_seen\": 14.0}, {\"site\": 320, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03788626799613741, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08977070914538081, \"functional effect\": -0.137, \"times_seen\": 12.0}, {\"site\": 320, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01260444911778134, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.08668329983503367, \"functional effect\": -0.6717, \"times_seen\": 5.0}, {\"site\": 320, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"323\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": null, \"functional effect\": -2.9699, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02068030148183524, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08619942359459185, \"functional effect\": -0.1638, \"times_seen\": 5.0}, {\"site\": 321, \"mutant\": \"D\", \"log2 fold change IC90\": 0.06412354039685071, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.09141824126111904, \"functional effect\": 0.0029, \"times_seen\": 15.0}, {\"site\": 321, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"G\", \"log2 fold change IC90\": -0.023854511495361545, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08600997656441466, \"functional effect\": -0.3656, \"times_seen\": 7.0}, {\"site\": 321, \"mutant\": \"K\", \"log2 fold change IC90\": -0.012372371383170223, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.0866972451813771, \"functional effect\": -0.5403, \"times_seen\": 58.0}, {\"site\": 321, \"mutant\": \"N\", \"log2 fold change IC90\": -0.022361539569421735, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08609902999732466, \"functional effect\": -0.5867, \"times_seen\": 7.0}, {\"site\": 321, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.29397427704781426, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.10720741593774444, \"functional effect\": -0.0984, \"times_seen\": 34.0}, {\"site\": 321, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": null, \"functional effect\": -0.3572, \"times_seen\": null}, {\"site\": 321, \"mutant\": \"T\", \"log2 fold change IC90\": 0.02121118742397275, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08873908707272173, \"functional effect\": -0.1734, \"times_seen\": 2.0}, {\"site\": 321, \"mutant\": \"V\", \"log2 fold change IC90\": 3.8155692869805505e-05, \"epitope\": \"all\", \"reference_site\": \"324\", \"IC90\": 0.08744625980161425, \"functional effect\": -0.7978, \"times_seen\": 10.0}, {\"site\": 322, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00911303841337846, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.0868933327942675, \"functional effect\": -0.6202, \"times_seen\": 6.0}, {\"site\": 322, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0026887545006938018, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08760706856570055, \"functional effect\": -1.2264, \"times_seen\": 15.0}, {\"site\": 322, \"mutant\": \"G\", \"log2 fold change IC90\": -0.02049426929271707, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08621053952758943, \"functional effect\": -0.7689, \"times_seen\": 2.0}, {\"site\": 322, \"mutant\": \"I\", \"log2 fold change IC90\": -0.014092152453345799, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.0865939583162859, \"functional effect\": -2.213, \"times_seen\": 3.0}, {\"site\": 322, \"mutant\": \"L\", \"log2 fold change IC90\": -0.007603408331518296, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08698430520406114, \"functional effect\": -1.5172, \"times_seen\": 2.0}, {\"site\": 322, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0736734015205812, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08309059120836962, \"functional effect\": -0.3715, \"times_seen\": 21.0}, {\"site\": 322, \"mutant\": \"R\", \"log2 fold change IC90\": 0.013095759163707558, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08824131452735763, \"functional effect\": -0.9655, \"times_seen\": 12.0}, {\"site\": 322, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 322, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.09251932614941454, \"epitope\": \"all\", \"reference_site\": \"325\", \"IC90\": 0.08201223745676496, \"functional effect\": -0.9614, \"times_seen\": 8.0}, {\"site\": 323, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": null, \"functional effect\": -3.2614, \"times_seen\": null}, {\"site\": 323, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 323, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03676635852265918, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.08970105058686478, \"functional effect\": -1.4178, \"times_seen\": 1.0}, {\"site\": 323, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0077833833741253544, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.08791698471402125, \"functional effect\": -1.7148, \"times_seen\": 1.0}, {\"site\": 323, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": null, \"functional effect\": -3.1291, \"times_seen\": null}, {\"site\": 323, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03449391116574309, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.08537801450043185, \"functional effect\": -1.0998, \"times_seen\": 1.0}, {\"site\": 323, \"mutant\": \"V\", \"log2 fold change IC90\": 0.9047781482138074, \"epitope\": \"all\", \"reference_site\": \"326\", \"IC90\": 0.1637175039958582, \"functional effect\": -0.3931, \"times_seen\": 9.0}, {\"site\": 324, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0017164439350387081, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08754804529447491, \"functional effect\": -0.7275, \"times_seen\": 3.0}, {\"site\": 324, \"mutant\": \"C\", \"log2 fold change IC90\": -0.00530963258486178, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08712271365551358, \"functional effect\": -2.6838, \"times_seen\": 2.0}, {\"site\": 324, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": null, \"functional effect\": -1.6056, \"times_seen\": null}, {\"site\": 324, \"mutant\": \"F\", \"log2 fold change IC90\": -0.007024687760203671, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08701920495993765, \"functional effect\": -1.3291, \"times_seen\": 3.0}, {\"site\": 324, \"mutant\": \"I\", \"log2 fold change IC90\": -0.635001784629749, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.056308656884091576, \"functional effect\": -0.1757, \"times_seen\": 21.0}, {\"site\": 324, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0018359226669024753, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08755529600393136, \"functional effect\": -0.3755, \"times_seen\": 11.0}, {\"site\": 324, \"mutant\": \"M\", \"log2 fold change IC90\": 0.04225194187856726, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.09004277163796946, \"functional effect\": -0.9679, \"times_seen\": 6.0}, {\"site\": 324, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 324, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.019217032023289386, \"epitope\": \"all\", \"reference_site\": \"327\", \"IC90\": 0.08628689666952073, \"functional effect\": -0.8286, \"times_seen\": 4.0}, {\"site\": 325, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02016982719378537, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08622992926201474, \"functional effect\": -2.836, \"times_seen\": 2.0}, {\"site\": 325, \"mutant\": \"D\", \"log2 fold change IC90\": -0.013993346436455233, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08659988908949867, \"functional effect\": -2.8843, \"times_seen\": 2.0}, {\"site\": 325, \"mutant\": \"G\", \"log2 fold change IC90\": -0.012187577186544155, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08670835090603388, \"functional effect\": -2.1289, \"times_seen\": 3.0}, {\"site\": 325, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0030082475264871177, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08726180259102115, \"functional effect\": -2.6076, \"times_seen\": 5.0}, {\"site\": 325, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -2.9665, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -2.6845, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0057363145575457155, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": 0.08709695062611814, \"functional effect\": -2.5307, \"times_seen\": 1.0}, {\"site\": 325, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -1.2725, \"times_seen\": null}, {\"site\": 325, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"328\", \"IC90\": null, \"functional effect\": -2.0587, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": null, \"functional effect\": -3.0183, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"I\", \"log2 fold change IC90\": 0.027354466162441436, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08911776119042687, \"functional effect\": -1.4592, \"times_seen\": 4.0}, {\"site\": 326, \"mutant\": \"L\", \"log2 fold change IC90\": 0.014174361289226115, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08830731105071805, \"functional effect\": -0.6351, \"times_seen\": 3.0}, {\"site\": 326, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": null, \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 326, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0007395029030134783, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.0873991361829727, \"functional effect\": -0.4705, \"times_seen\": 1.0}, {\"site\": 326, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005288757233137361, \"epitope\": \"all\", \"reference_site\": \"329\", \"IC90\": 0.08712397430339647, \"functional effect\": -0.0063, \"times_seen\": 2.0}, {\"site\": 327, \"mutant\": \"A\", \"log2 fold change IC90\": 0.011935414695839785, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08817037149812737, \"functional effect\": -0.7972, \"times_seen\": 3.0}, {\"site\": 327, \"mutant\": \"G\", \"log2 fold change IC90\": -0.009780508836301712, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08685314043669594, \"functional effect\": -2.3054, \"times_seen\": 2.0}, {\"site\": 327, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04712755508726747, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08463362544552733, \"functional effect\": -2.0515, \"times_seen\": 13.0}, {\"site\": 327, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 327, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": null, \"functional effect\": -2.5724, \"times_seen\": null}, {\"site\": 327, \"mutant\": \"S\", \"log2 fold change IC90\": -0.017807191603290497, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08637125976134126, \"functional effect\": -0.7268, \"times_seen\": 9.0}, {\"site\": 327, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04135714097937586, \"epitope\": \"all\", \"reference_site\": \"330\", \"IC90\": 0.08497281635978135, \"functional effect\": -0.5332, \"times_seen\": 8.0}, {\"site\": 328, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04201692394121756, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.0849339649066849, \"functional effect\": -0.6479, \"times_seen\": 7.0}, {\"site\": 328, \"mutant\": \"E\", \"log2 fold change IC90\": -0.050731686741991563, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08442245813431476, \"functional effect\": -0.8157, \"times_seen\": 6.0}, {\"site\": 328, \"mutant\": \"H\", \"log2 fold change IC90\": -0.029488688780792954, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.085674735626839, \"functional effect\": -0.4035, \"times_seen\": 4.0}, {\"site\": 328, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04122164646755794, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08498079718082419, \"functional effect\": -0.5622, \"times_seen\": 9.0}, {\"site\": 328, \"mutant\": \"K\", \"log2 fold change IC90\": 0.00017562275914565845, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08745459250754185, \"functional effect\": -0.3715, \"times_seen\": 2.0}, {\"site\": 328, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 328, \"mutant\": \"S\", \"log2 fold change IC90\": -0.037935456188682645, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08517458821627433, \"functional effect\": -0.8968, \"times_seen\": 10.0}, {\"site\": 328, \"mutant\": \"T\", \"log2 fold change IC90\": -0.009856905185235982, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08684854134474905, \"functional effect\": -1.143, \"times_seen\": 2.0}, {\"site\": 328, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0032589572661024897, \"epitope\": \"all\", \"reference_site\": \"331\", \"IC90\": 0.08724663966165362, \"functional effect\": -0.7836, \"times_seen\": 6.0}, {\"site\": 329, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": null, \"functional effect\": -0.3912, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": null, \"functional effect\": -1.7635, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": null, \"functional effect\": 0.087, \"times_seen\": null}, {\"site\": 329, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0016238368100072523, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08754242573362624, \"functional effect\": -1.0754, \"times_seen\": 2.0}, {\"site\": 329, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0035078828571858674, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08723158724432874, \"functional effect\": -0.7585, \"times_seen\": 8.0}, {\"site\": 329, \"mutant\": \"V\", \"log2 fold change IC90\": 0.012022911576338197, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08817571903602268, \"functional effect\": -0.3776, \"times_seen\": 8.0}, {\"site\": 329, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.023314750741350303, \"epitope\": \"all\", \"reference_site\": \"332\", \"IC90\": 0.08604216181085392, \"functional effect\": 0.2852, \"times_seen\": 11.0}, {\"site\": 330, \"mutant\": \"A\", \"log2 fold change IC90\": 0.3992508846205932, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.11532308320392703, \"functional effect\": -0.7535, \"times_seen\": 12.0}, {\"site\": 330, \"mutant\": \"F\", \"log2 fold change IC90\": 0.018342804071208457, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08856283024570538, \"functional effect\": -1.5184, \"times_seen\": 2.0}, {\"site\": 330, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06590039395492314, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08353947805525563, \"functional effect\": -1.1133, \"times_seen\": 19.0}, {\"site\": 330, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03850721174410741, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08514083929920521, \"functional effect\": -0.5261, \"times_seen\": 6.0}, {\"site\": 330, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010109746931858702, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08683332190325126, \"functional effect\": -1.2929, \"times_seen\": 3.0}, {\"site\": 330, \"mutant\": \"N\", \"log2 fold change IC90\": -0.024869048996135058, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08594951356315166, \"functional effect\": -0.6052, \"times_seen\": 3.0}, {\"site\": 330, \"mutant\": \"P\", \"log2 fold change IC90\": -0.025538488936502308, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.0859096404865438, \"functional effect\": -0.9414, \"times_seen\": 13.0}, {\"site\": 330, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0027817593659027135, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08727550286449004, \"functional effect\": 0.1851, \"times_seen\": 1.0}, {\"site\": 330, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 330, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.035286585006991195, \"epitope\": \"all\", \"reference_site\": \"333\", \"IC90\": 0.08533111731980228, \"functional effect\": -1.0236, \"times_seen\": 9.0}, {\"site\": 331, \"mutant\": \"D\", \"log2 fold change IC90\": -0.02296235626282622, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08606318114292374, \"functional effect\": 0.1305, \"times_seen\": 5.0}, {\"site\": 331, \"mutant\": \"H\", \"log2 fold change IC90\": -0.006944101961807422, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08702406579869026, \"functional effect\": -0.3008, \"times_seen\": 10.0}, {\"site\": 331, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": null, \"functional effect\": -1.0289, \"times_seen\": null}, {\"site\": 331, \"mutant\": \"K\", \"log2 fold change IC90\": -0.08186900380656446, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08261991179018299, \"functional effect\": -0.0467, \"times_seen\": 13.0}, {\"site\": 331, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 331, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.017575363508773492, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.0863851399597691, \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 331, \"mutant\": \"S\", \"log2 fold change IC90\": -0.036402587669298776, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08526513460812668, \"functional effect\": 0.1552, \"times_seen\": 9.0}, {\"site\": 331, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12468096436285954, \"epitope\": \"all\", \"reference_site\": \"334\", \"IC90\": 0.08020418732602891, \"functional effect\": -0.6434, \"times_seen\": 15.0}, {\"site\": 332, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04337408663248651, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08485410394891162, \"functional effect\": 0.1562, \"times_seen\": 6.0}, {\"site\": 332, \"mutant\": \"F\", \"log2 fold change IC90\": 0.019279093283715718, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08862032495745327, \"functional effect\": -0.5329, \"times_seen\": 11.0}, {\"site\": 332, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 332, \"mutant\": \"M\", \"log2 fold change IC90\": 0.014058573913205287, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08830022399403671, \"functional effect\": -0.1499, \"times_seen\": 2.0}, {\"site\": 332, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0551466983341536, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08416449897871955, \"functional effect\": 0.3107, \"times_seen\": 44.0}, {\"site\": 332, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004557421286591273, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08716815068505084, \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 332, \"mutant\": \"R\", \"log2 fold change IC90\": 0.00042018456702800245, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08746941883297465, \"functional effect\": 0.1127, \"times_seen\": 3.0}, {\"site\": 332, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03150785063501932, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.0893746925767932, \"functional effect\": -0.1485, \"times_seen\": 4.0}, {\"site\": 332, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004034118618090384, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08719977455461173, \"functional effect\": -0.1033, \"times_seen\": 5.0}, {\"site\": 332, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05320213039971074, \"epitope\": \"all\", \"reference_site\": \"335\", \"IC90\": 0.08427801841950795, \"functional effect\": 0.1043, \"times_seen\": 10.0}, {\"site\": 333, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": null, \"functional effect\": -1.984, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": null, \"functional effect\": -2.0218, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": null, \"functional effect\": -2.8487, \"times_seen\": null}, {\"site\": 333, \"mutant\": \"S\", \"log2 fold change IC90\": -0.002691339627450894, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08728097295707245, \"functional effect\": -3.0902, \"times_seen\": 1.0}, {\"site\": 333, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00513290599236979, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08713338662724794, \"functional effect\": -0.5053, \"times_seen\": 1.0}, {\"site\": 333, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004018374288892945, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.0872007261829247, \"functional effect\": -3.0351, \"times_seen\": 1.0}, {\"site\": 333, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0030607854367011517, \"epitope\": \"all\", \"reference_site\": \"336\", \"IC90\": 0.08725862487906953, \"functional effect\": -3.0805, \"times_seen\": 1.0}, {\"site\": 334, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": null, \"functional effect\": -0.4448, \"times_seen\": null}, {\"site\": 334, \"mutant\": \"H\", \"log2 fold change IC90\": 0.020420459597403583, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08869046332505966, \"functional effect\": -0.5521, \"times_seen\": 7.0}, {\"site\": 334, \"mutant\": \"L\", \"log2 fold change IC90\": 0.05935042574985658, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.09111628644449106, \"functional effect\": -1.2878, \"times_seen\": 24.0}, {\"site\": 334, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 334, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.029640710997821635, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08566570823249028, \"functional effect\": -0.5949, \"times_seen\": 5.0}, {\"site\": 334, \"mutant\": \"R\", \"log2 fold change IC90\": 0.036389259188727555, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.0896776071112732, \"functional effect\": -0.0135, \"times_seen\": 4.0}, {\"site\": 334, \"mutant\": \"S\", \"log2 fold change IC90\": -0.031179445197137015, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08557438852848709, \"functional effect\": -0.2692, \"times_seen\": 29.0}, {\"site\": 334, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06869666004330588, \"epitope\": \"all\", \"reference_site\": \"337\", \"IC90\": 0.08337771665323233, \"functional effect\": -0.9523, \"times_seen\": 26.0}, {\"site\": 335, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.8826, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"I\", \"log2 fold change IC90\": 0.004260830058382893, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": 0.08770258424473475, \"functional effect\": -1.541, \"times_seen\": 1.0}, {\"site\": 335, \"mutant\": \"L\", \"log2 fold change IC90\": 0.19112692517815888, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": 0.09983083193106825, \"functional effect\": -0.2003, \"times_seen\": 16.0}, {\"site\": 335, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.9682, \"times_seen\": null}, {\"site\": 335, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"338\", \"IC90\": null, \"functional effect\": -2.6032, \"times_seen\": null}, {\"site\": 336, \"mutant\": \"*\", \"log2 fold change IC90\": -0.007978557920268935, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08696168927828414, \"functional effect\": -2.9687, \"times_seen\": 2.0}, {\"site\": 336, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 336, \"mutant\": \"A\", \"log2 fold change IC90\": 0.43951545558926747, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.11858700165013462, \"functional effect\": -0.0839, \"times_seen\": 90.0}, {\"site\": 336, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03941536058703594, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08508726163954214, \"functional effect\": -2.0663, \"times_seen\": 14.0}, {\"site\": 336, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 336, \"mutant\": \"E\", \"log2 fold change IC90\": -0.5725918106299654, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.0587979849244496, \"functional effect\": 0.1538, \"times_seen\": 47.0}, {\"site\": 336, \"mutant\": \"F\", \"log2 fold change IC90\": -0.20410293248575506, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.07590819209201237, \"functional effect\": -0.3194, \"times_seen\": 20.0}, {\"site\": 336, \"mutant\": \"G\", \"log2 fold change IC90\": -0.5981360590752677, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.0577660747047527, \"functional effect\": -0.2671, \"times_seen\": 97.0}, {\"site\": 336, \"mutant\": \"H\", \"log2 fold change IC90\": 0.005415381058158292, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08777279841402562, \"functional effect\": 0.1039, \"times_seen\": 23.0}, {\"site\": 336, \"mutant\": \"I\", \"log2 fold change IC90\": 0.5369389809661727, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.1268716219306313, \"functional effect\": 0.0518, \"times_seen\": 28.0}, {\"site\": 336, \"mutant\": \"K\", \"log2 fold change IC90\": 0.11737718620404147, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.09485578154674071, \"functional effect\": -0.2848, \"times_seen\": 20.0}, {\"site\": 336, \"mutant\": \"L\", \"log2 fold change IC90\": 0.2700407031338764, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.10544357075805061, \"functional effect\": 0.1498, \"times_seen\": 72.0}, {\"site\": 336, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06080562454314631, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08383501298359729, \"functional effect\": 0.024, \"times_seen\": 19.0}, {\"site\": 336, \"mutant\": \"N\", \"log2 fold change IC90\": 0.41372030750203354, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.11648552870437039, \"functional effect\": -0.1268, \"times_seen\": 37.0}, {\"site\": 336, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0005099208662472487, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08741304547616865, \"functional effect\": -0.5614, \"times_seen\": 56.0}, {\"site\": 336, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.031575616950484206, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08937889078617742, \"functional effect\": 0.0728, \"times_seen\": 24.0}, {\"site\": 336, \"mutant\": \"R\", \"log2 fold change IC90\": -0.46271188727399276, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.06345116426989222, \"functional effect\": -0.2837, \"times_seen\": 60.0}, {\"site\": 336, \"mutant\": \"S\", \"log2 fold change IC90\": 0.27915574623730455, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.10611187922801604, \"functional effect\": -0.143, \"times_seen\": 99.0}, {\"site\": 336, \"mutant\": \"T\", \"log2 fold change IC90\": 1.2330432692144082, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.20554776685431406, \"functional effect\": -0.0781, \"times_seen\": 62.0}, {\"site\": 336, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1215682190846317, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.08037742194525005, \"functional effect\": 0.1474, \"times_seen\": 83.0}, {\"site\": 336, \"mutant\": \"W\", \"log2 fold change IC90\": 0.6984450659637684, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.14190008905046084, \"functional effect\": 0.011, \"times_seen\": 32.0}, {\"site\": 336, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12872277343791697, \"epitope\": \"all\", \"reference_site\": \"339\", \"IC90\": 0.07997980425509618, \"functional effect\": -0.2646, \"times_seen\": 30.0}, {\"site\": 337, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": null, \"functional effect\": -3.134, \"times_seen\": null}, {\"site\": 337, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 337, \"mutant\": \"A\", \"log2 fold change IC90\": -0.011601965454067085, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08674355428111473, \"functional effect\": -0.5449, \"times_seen\": 10.0}, {\"site\": 337, \"mutant\": \"D\", \"log2 fold change IC90\": -0.15811065838045446, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.07836708667582845, \"functional effect\": -0.3, \"times_seen\": 42.0}, {\"site\": 337, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 337, \"mutant\": \"G\", \"log2 fold change IC90\": -0.010655620545828269, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08680047292849397, \"functional effect\": -1.2106, \"times_seen\": 11.0}, {\"site\": 337, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0853488544652307, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.09277315327307517, \"functional effect\": -0.3866, \"times_seen\": 82.0}, {\"site\": 337, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03990608779359793, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08505832445427386, \"functional effect\": -0.4231, \"times_seen\": 22.0}, {\"site\": 337, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05486454176962924, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08418096114680937, \"functional effect\": -0.356, \"times_seen\": 13.0}, {\"site\": 337, \"mutant\": \"V\", \"log2 fold change IC90\": -0.015891576622679923, \"epitope\": \"all\", \"reference_site\": \"340\", \"IC90\": 0.08648601996239264, \"functional effect\": -0.9399, \"times_seen\": 10.0}, {\"site\": 338, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -2.9882, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0075293811558783666, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08790150733120393, \"functional effect\": -0.1591, \"times_seen\": 9.0}, {\"site\": 338, \"mutant\": \"I\", \"log2 fold change IC90\": -0.030308809077758656, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.0856260464581273, \"functional effect\": 0.2472, \"times_seen\": 25.0}, {\"site\": 338, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01024977310645726, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08682489437872068, \"functional effect\": 0.2113, \"times_seen\": 5.0}, {\"site\": 338, \"mutant\": \"M\", \"log2 fold change IC90\": -0.058694874829392764, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.08395775842563734, \"functional effect\": -0.6083, \"times_seen\": 9.0}, {\"site\": 338, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": null, \"functional effect\": -3.0848, \"times_seen\": null}, {\"site\": 338, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"341\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": null, \"functional effect\": -2.879, \"times_seen\": null}, {\"site\": 339, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05024475144641047, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.08445095702812694, \"functional effect\": -0.9156, \"times_seen\": 26.0}, {\"site\": 339, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01150169234592369, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.08674958351656244, \"functional effect\": -2.5995, \"times_seen\": 1.0}, {\"site\": 339, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02170291996797359, \"epitope\": \"all\", \"reference_site\": \"342\", \"IC90\": 0.08613834492738338, \"functional effect\": -2.1252, \"times_seen\": 4.0}, {\"site\": 340, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": null, \"functional effect\": -2.2649, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"D\", \"log2 fold change IC90\": -0.08953406212282088, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08218211511812963, \"functional effect\": -2.1705, \"times_seen\": 5.0}, {\"site\": 340, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": null, \"functional effect\": -3.2684, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0009919686277875264, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08738384303017119, \"functional effect\": -1.0153, \"times_seen\": 6.0}, {\"site\": 340, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"S\", \"log2 fold change IC90\": -0.022296112358871287, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08610293473598479, \"functional effect\": -1.1804, \"times_seen\": 9.0}, {\"site\": 340, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": null, \"functional effect\": -2.0563, \"times_seen\": null}, {\"site\": 340, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.014809203133446946, \"epitope\": \"all\", \"reference_site\": \"343\", \"IC90\": 0.08834617824785475, \"functional effect\": -1.4042, \"times_seen\": 4.0}, {\"site\": 341, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": null, \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 341, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 341, \"mutant\": \"D\", \"log2 fold change IC90\": -0.02867006349410589, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.0857233636495383, \"functional effect\": -1.243, \"times_seen\": 8.0}, {\"site\": 341, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": null, \"functional effect\": -2.5035, \"times_seen\": null}, {\"site\": 341, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011462410067257475, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08675194560114104, \"functional effect\": -0.3353, \"times_seen\": 7.0}, {\"site\": 341, \"mutant\": \"S\", \"log2 fold change IC90\": -0.057985645488691784, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08399904223310266, \"functional effect\": -0.2672, \"times_seen\": 36.0}, {\"site\": 341, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02529674118801819, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08592403729371462, \"functional effect\": -0.5728, \"times_seen\": 65.0}, {\"site\": 341, \"mutant\": \"V\", \"log2 fold change IC90\": -0.049365544521116404, \"epitope\": \"all\", \"reference_site\": \"344\", \"IC90\": 0.08450243879899871, \"functional effect\": -0.4456, \"times_seen\": 42.0}, {\"site\": 342, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": null, \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 342, \"mutant\": \"H\", \"log2 fold change IC90\": -0.026819917215963746, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.0858333678416101, \"functional effect\": -0.6463, \"times_seen\": 5.0}, {\"site\": 342, \"mutant\": \"I\", \"log2 fold change IC90\": -0.009499386337189608, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08687006622505447, \"functional effect\": -1.1581, \"times_seen\": 2.0}, {\"site\": 342, \"mutant\": \"N\", \"log2 fold change IC90\": -0.010890872706256835, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08678632001785984, \"functional effect\": -2.2256, \"times_seen\": 3.0}, {\"site\": 342, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01831997340296727, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.08634056599814253, \"functional effect\": -0.1618, \"times_seen\": 16.0}, {\"site\": 342, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"345\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 343, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": null, \"functional effect\": -1.7992, \"times_seen\": null}, {\"site\": 343, \"mutant\": \"G\", \"log2 fold change IC90\": -0.24312932750210528, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.07388232136633507, \"functional effect\": -0.8701, \"times_seen\": 13.0}, {\"site\": 343, \"mutant\": \"I\", \"log2 fold change IC90\": -2.035635521008296, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.021327620322407637, \"functional effect\": -0.1825, \"times_seen\": 38.0}, {\"site\": 343, \"mutant\": \"K\", \"log2 fold change IC90\": 0.42372800304053937, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.1172963753038716, \"functional effect\": 0.0144, \"times_seen\": 40.0}, {\"site\": 343, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0032894028983625166, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.08764355028876103, \"functional effect\": -0.433, \"times_seen\": 3.0}, {\"site\": 343, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.8570385924485606, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.0482764613630197, \"functional effect\": -0.0793, \"times_seen\": 21.0}, {\"site\": 343, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 343, \"mutant\": \"S\", \"log2 fold change IC90\": -2.523037244445398, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.015213175035073263, \"functional effect\": -0.0179, \"times_seen\": 36.0}, {\"site\": 343, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011828525674460992, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": 0.08672993317951082, \"functional effect\": -0.0394, \"times_seen\": 46.0}, {\"site\": 343, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"346\", \"IC90\": null, \"functional effect\": -1.4097, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": null, \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"C\", \"log2 fold change IC90\": 0.027276464169807075, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08911294300304898, \"functional effect\": -2.9264, \"times_seen\": 1.0}, {\"site\": 345, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": null, \"functional effect\": -2.6967, \"times_seen\": null}, {\"site\": 345, \"mutant\": \"E\", \"log2 fold change IC90\": 0.029059999097948996, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.0892231772000926, \"functional effect\": -1.2666, \"times_seen\": 11.0}, {\"site\": 345, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0014965347867789594, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.0875347014149515, \"functional effect\": -0.8318, \"times_seen\": 1.0}, {\"site\": 345, \"mutant\": \"L\", \"log2 fold change IC90\": -0.011234220856398693, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08676566812951417, \"functional effect\": -2.7247, \"times_seen\": 1.0}, {\"site\": 345, \"mutant\": \"P\", \"log2 fold change IC90\": 0.007670896092603019, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.0879101300726765, \"functional effect\": 0.286, \"times_seen\": 15.0}, {\"site\": 345, \"mutant\": \"S\", \"log2 fold change IC90\": -0.12983076294212526, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.07991840336230438, \"functional effect\": -0.1404, \"times_seen\": 54.0}, {\"site\": 345, \"mutant\": \"T\", \"log2 fold change IC90\": -0.053596235999118745, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.08425499906906249, \"functional effect\": -1.4223, \"times_seen\": 66.0}, {\"site\": 345, \"mutant\": \"V\", \"log2 fold change IC90\": 0.06802279446395153, \"epitope\": \"all\", \"reference_site\": \"348\", \"IC90\": 0.09166565675057983, \"functional effect\": -2.0791, \"times_seen\": 18.0}, {\"site\": 346, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.7891, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05348512914192989, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.09074660390783143, \"functional effect\": -2.3199, \"times_seen\": 7.0}, {\"site\": 346, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.9226, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005040314740198871, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.08713897897216033, \"functional effect\": -2.6787, \"times_seen\": 1.0}, {\"site\": 346, \"mutant\": \"P\", \"log2 fold change IC90\": -0.02009366709972198, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.08623448147345544, \"functional effect\": -0.9486, \"times_seen\": 42.0}, {\"site\": 346, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.9673, \"times_seen\": null}, {\"site\": 346, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"349\", \"IC90\": null, \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": null, \"functional effect\": -1.3334, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"A\", \"log2 fold change IC90\": 0.008968949529753948, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08798926210985027, \"functional effect\": -2.7213, \"times_seen\": 6.0}, {\"site\": 347, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0027466367690211816, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08727762762372969, \"functional effect\": -2.8082, \"times_seen\": 1.0}, {\"site\": 347, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"F\", \"log2 fold change IC90\": -0.007859127965551485, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08696888848547128, \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 347, \"mutant\": \"I\", \"log2 fold change IC90\": -0.017456473223849748, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.08639225911995581, \"functional effect\": -2.448, \"times_seen\": 3.0}, {\"site\": 347, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": null, \"functional effect\": -2.9322, \"times_seen\": null}, {\"site\": 347, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"350\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -2.1682, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -2.0452, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -3.2741, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -3.2547, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"F\", \"log2 fold change IC90\": -0.011518563231327869, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.08674856907228726, \"functional effect\": -0.2001, \"times_seen\": 8.0}, {\"site\": 348, \"mutant\": \"H\", \"log2 fold change IC90\": -1.012535093835802, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.04334373354886035, \"functional effect\": -1.3139, \"times_seen\": 36.0}, {\"site\": 348, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01871296443066075, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.08858555622319664, \"functional effect\": -1.8702, \"times_seen\": 2.0}, {\"site\": 348, \"mutant\": \"M\", \"log2 fold change IC90\": 0.013298907315194782, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.08825374080011832, \"functional effect\": -1.7304, \"times_seen\": 2.0}, {\"site\": 348, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": null, \"functional effect\": -2.7372, \"times_seen\": null}, {\"site\": 348, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"351\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": null, \"functional effect\": -2.7571, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"C\", \"log2 fold change IC90\": 0.024547011514133518, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.08894450850194657, \"functional effect\": -1.6949, \"times_seen\": 5.0}, {\"site\": 349, \"mutant\": \"D\", \"log2 fold change IC90\": -0.014315460583654701, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.08658055587300872, \"functional effect\": -1.3905, \"times_seen\": 4.0}, {\"site\": 349, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": null, \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"M\", \"log2 fold change IC90\": -0.016563953403504576, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.0864457220191074, \"functional effect\": -0.151, \"times_seen\": 3.0}, {\"site\": 349, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 349, \"mutant\": \"S\", \"log2 fold change IC90\": -0.188370262456372, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.07674050512990419, \"functional effect\": -0.3134, \"times_seen\": 29.0}, {\"site\": 349, \"mutant\": \"T\", \"log2 fold change IC90\": -0.055907047533039815, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.08412015312120265, \"functional effect\": -1.7921, \"times_seen\": 11.0}, {\"site\": 349, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05243134989358055, \"epitope\": \"all\", \"reference_site\": \"352\", \"IC90\": 0.08432305718917771, \"functional effect\": -2.0636, \"times_seen\": 12.0}, {\"site\": 350, \"mutant\": \"*\", \"log2 fold change IC90\": -0.017313764954042875, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08640080527785331, \"functional effect\": -2.6704, \"times_seen\": 14.0}, {\"site\": 350, \"mutant\": \"C\", \"log2 fold change IC90\": -0.022010615131153644, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08611997546942432, \"functional effect\": -1.6642, \"times_seen\": 4.0}, {\"site\": 350, \"mutant\": \"F\", \"log2 fold change IC90\": -0.005478381728502379, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08711252368250266, \"functional effect\": -1.2602, \"times_seen\": 3.0}, {\"site\": 350, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": null, \"functional effect\": -2.7008, \"times_seen\": null}, {\"site\": 350, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": null, \"functional effect\": -0.759, \"times_seen\": null}, {\"site\": 350, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01147495123291992, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.08675119148071939, \"functional effect\": -2.2285, \"times_seen\": 4.0}, {\"site\": 350, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"353\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 351, \"mutant\": \"D\", \"log2 fold change IC90\": 0.25479077189271004, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.10433485523107787, \"functional effect\": 0.0623, \"times_seen\": 14.0}, {\"site\": 351, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004290335860223845, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.0871842895759434, \"functional effect\": 0.147, \"times_seen\": 2.0}, {\"site\": 351, \"mutant\": \"G\", \"log2 fold change IC90\": -0.003824945494457642, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08721241837125213, \"functional effect\": -0.4126, \"times_seen\": 1.0}, {\"site\": 351, \"mutant\": \"H\", \"log2 fold change IC90\": -0.013725971435107572, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08661594015404532, \"functional effect\": -0.0631, \"times_seen\": 23.0}, {\"site\": 351, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": null, \"functional effect\": -0.3727, \"times_seen\": null}, {\"site\": 351, \"mutant\": \"K\", \"log2 fold change IC90\": 1.031637373524287, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.17876543371234344, \"functional effect\": -0.0079, \"times_seen\": 37.0}, {\"site\": 351, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 351, \"mutant\": \"S\", \"log2 fold change IC90\": 0.09699298002219904, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.09352496388786809, \"functional effect\": -0.0514, \"times_seen\": 17.0}, {\"site\": 351, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02241218598623745, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08609600750768027, \"functional effect\": 0.0793, \"times_seen\": 12.0}, {\"site\": 351, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004638880740244496, \"epitope\": \"all\", \"reference_site\": \"354\", \"IC90\": 0.08716322901465665, \"functional effect\": -1.1562, \"times_seen\": 9.0}, {\"site\": 352, \"mutant\": \"G\", \"log2 fold change IC90\": -0.1894399564693031, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.0766836265578791, \"functional effect\": -2.9596, \"times_seen\": 2.0}, {\"site\": 352, \"mutant\": \"K\", \"log2 fold change IC90\": -0.014270264021530572, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.0865832682998607, \"functional effect\": -2.7349, \"times_seen\": 2.0}, {\"site\": 352, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -3.0142, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -2.9914, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -2.6016, \"times_seen\": null}, {\"site\": 352, \"mutant\": \"T\", \"log2 fold change IC90\": -0.008096355186551543, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": 0.08695458907291856, \"functional effect\": -2.9759, \"times_seen\": 1.0}, {\"site\": 352, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"355\", \"IC90\": null, \"functional effect\": -2.7663, \"times_seen\": null}, {\"site\": 353, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0026316544925191615, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.08728458389650125, \"functional effect\": -0.879, \"times_seen\": 8.0}, {\"site\": 353, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": null, \"functional effect\": -2.6337, \"times_seen\": null}, {\"site\": 353, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 353, \"mutant\": \"M\", \"log2 fold change IC90\": -0.038418240559928915, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.08514609010735427, \"functional effect\": 0.0611, \"times_seen\": 16.0}, {\"site\": 353, \"mutant\": \"N\", \"log2 fold change IC90\": -0.22333755027013458, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.07490286870012715, \"functional effect\": -0.716, \"times_seen\": 43.0}, {\"site\": 353, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008963500882536845, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.08690233988689756, \"functional effect\": 0.1857, \"times_seen\": 6.0}, {\"site\": 353, \"mutant\": \"R\", \"log2 fold change IC90\": 0.28304842850155754, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.10639857709519378, \"functional effect\": -0.0135, \"times_seen\": 63.0}, {\"site\": 353, \"mutant\": \"T\", \"log2 fold change IC90\": -0.3604375128189423, \"epitope\": \"all\", \"reference_site\": \"356\", \"IC90\": 0.06811256728068663, \"functional effect\": 0.1867, \"times_seen\": 5.0}, {\"site\": 354, \"mutant\": \"E\", \"log2 fold change IC90\": -0.077452567003722, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08287321874724346, \"functional effect\": -0.5066, \"times_seen\": 8.0}, {\"site\": 354, \"mutant\": \"G\", \"log2 fold change IC90\": -1.0290644032338057, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.0428499678074485, \"functional effect\": -1.2627, \"times_seen\": 12.0}, {\"site\": 354, \"mutant\": \"I\", \"log2 fold change IC90\": -0.037355088767321874, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.08520885914597605, \"functional effect\": 0.0912, \"times_seen\": 8.0}, {\"site\": 354, \"mutant\": \"K\", \"log2 fold change IC90\": 0.04119041719813308, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.0899765431795648, \"functional effect\": 0.1788, \"times_seen\": 61.0}, {\"site\": 354, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01748675944829175, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.0863904455226175, \"functional effect\": -0.1804, \"times_seen\": 9.0}, {\"site\": 354, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 354, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03755371515572835, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.0851971286260459, \"functional effect\": -0.1978, \"times_seen\": 6.0}, {\"site\": 354, \"mutant\": \"T\", \"log2 fold change IC90\": -0.009342312255674093, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": 0.0868795247580836, \"functional effect\": -0.0626, \"times_seen\": 1.0}, {\"site\": 354, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"357\", \"IC90\": null, \"functional effect\": -1.6586, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"E\", \"log2 fold change IC90\": -0.00515782859521138, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.0871318814082165, \"functional effect\": -2.5714, \"times_seen\": 1.0}, {\"site\": 355, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03431001250319927, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08954845468477848, \"functional effect\": -0.1098, \"times_seen\": 5.0}, {\"site\": 355, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": null, \"functional effect\": -1.5589, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"N\", \"log2 fold change IC90\": -0.021852583468520908, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08612940949944986, \"functional effect\": -2.9698, \"times_seen\": 1.0}, {\"site\": 355, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004733236477002086, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08715752851557788, \"functional effect\": -2.0747, \"times_seen\": 1.0}, {\"site\": 355, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": null, \"functional effect\": -3.2049, \"times_seen\": null}, {\"site\": 355, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02148854360779976, \"epitope\": \"all\", \"reference_site\": \"358\", \"IC90\": 0.08615114555147589, \"functional effect\": -1.0623, \"times_seen\": 5.0}, {\"site\": 356, \"mutant\": \"A\", \"log2 fold change IC90\": -0.014562750630112664, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08656571651041879, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 356, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": null, \"functional effect\": -0.9389, \"times_seen\": null}, {\"site\": 356, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0781462659230058, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08283337994453117, \"functional effect\": -1.0958, \"times_seen\": 40.0}, {\"site\": 356, \"mutant\": \"I\", \"log2 fold change IC90\": -0.14267207850574143, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.07921021236528901, \"functional effect\": -0.7569, \"times_seen\": 17.0}, {\"site\": 356, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005474347738671252, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.08711276726241113, \"functional effect\": -1.8765, \"times_seen\": 1.0}, {\"site\": 356, \"mutant\": \"N\", \"log2 fold change IC90\": -0.20591917369205753, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.0758126896908998, \"functional effect\": -0.2229, \"times_seen\": 57.0}, {\"site\": 356, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08588997292359948, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.0823899605003494, \"functional effect\": -0.2929, \"times_seen\": 38.0}, {\"site\": 356, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 356, \"mutant\": \"T\", \"log2 fold change IC90\": -0.4550249523790189, \"epitope\": \"all\", \"reference_site\": \"359\", \"IC90\": 0.06379014559414756, \"functional effect\": -0.1307, \"times_seen\": 15.0}, {\"site\": 357, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01815768212876335, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08635027914488448, \"functional effect\": -1.1934, \"times_seen\": 3.0}, {\"site\": 357, \"mutant\": \"D\", \"log2 fold change IC90\": -0.07417048994766161, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08306196682463984, \"functional effect\": 0.1485, \"times_seen\": 20.0}, {\"site\": 357, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": null, \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 357, \"mutant\": \"K\", \"log2 fold change IC90\": 0.008717782021389264, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08797394486022568, \"functional effect\": -1.5839, \"times_seen\": 9.0}, {\"site\": 357, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014750306249205826, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.0865544633829208, \"functional effect\": -2.5769, \"times_seen\": 1.0}, {\"site\": 357, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 357, \"mutant\": \"S\", \"log2 fold change IC90\": -0.014341746844980617, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.0865789783681865, \"functional effect\": -0.6761, \"times_seen\": 10.0}, {\"site\": 357, \"mutant\": \"T\", \"log2 fold change IC90\": -0.007229911490284697, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08700682733666777, \"functional effect\": -2.6163, \"times_seen\": 8.0}, {\"site\": 357, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.033559443632485066, \"epitope\": \"all\", \"reference_site\": \"360\", \"IC90\": 0.08543333376374129, \"functional effect\": -0.9013, \"times_seen\": 11.0}, {\"site\": 358, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -3.1294, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"F\", \"log2 fold change IC90\": 0.01658731120077625, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.088455131209484, \"functional effect\": -2.0623, \"times_seen\": 1.0}, {\"site\": 358, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -3.2653, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -3.1037, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"R\", \"log2 fold change IC90\": -0.17185966152984508, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.07762378932180065, \"functional effect\": -3.0611, \"times_seen\": 2.0}, {\"site\": 358, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -2.8591, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -2.9714, \"times_seen\": null}, {\"site\": 358, \"mutant\": \"V\", \"log2 fold change IC90\": 0.8460238816070466, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": 0.15718399340654157, \"functional effect\": -2.0774, \"times_seen\": 2.0}, {\"site\": 358, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"361\", \"IC90\": null, \"functional effect\": -2.9122, \"times_seen\": null}, {\"site\": 359, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 359, \"mutant\": \"A\", \"log2 fold change IC90\": -0.005185140673163137, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08713023190493001, \"functional effect\": -1.5445, \"times_seen\": 1.0}, {\"site\": 359, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": null, \"functional effect\": -2.8474, \"times_seen\": null}, {\"site\": 359, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03200933841270882, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08552517703170302, \"functional effect\": -2.0064, \"times_seen\": 8.0}, {\"site\": 359, \"mutant\": \"I\", \"log2 fold change IC90\": -0.006053157046049383, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08707782462670739, \"functional effect\": 0.3073, \"times_seen\": 19.0}, {\"site\": 359, \"mutant\": \"L\", \"log2 fold change IC90\": -0.034960353689320996, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08535041511296441, \"functional effect\": -0.6073, \"times_seen\": 8.0}, {\"site\": 359, \"mutant\": \"M\", \"log2 fold change IC90\": -0.04609250016917962, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.08469436723749008, \"functional effect\": -0.4763, \"times_seen\": 9.0}, {\"site\": 359, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"362\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 360, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 360, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 360, \"mutant\": \"D\", \"log2 fold change IC90\": -0.011306032062722104, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.08676134941207783, \"functional effect\": -2.4604, \"times_seen\": 1.0}, {\"site\": 360, \"mutant\": \"L\", \"log2 fold change IC90\": -0.021683311663083026, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.08613951567959396, \"functional effect\": 0.1011, \"times_seen\": 4.0}, {\"site\": 360, \"mutant\": \"S\", \"log2 fold change IC90\": -0.037980566519391655, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.08517192501049335, \"functional effect\": -0.5295, \"times_seen\": 7.0}, {\"site\": 360, \"mutant\": \"T\", \"log2 fold change IC90\": -0.14148831797034536, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.07927523262229692, \"functional effect\": -0.8575, \"times_seen\": 30.0}, {\"site\": 360, \"mutant\": \"V\", \"log2 fold change IC90\": -1.546778385239421, \"epitope\": \"all\", \"reference_site\": \"363\", \"IC90\": 0.02992974813802945, \"functional effect\": -0.3613, \"times_seen\": 15.0}, {\"site\": 361, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 361, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 361, \"mutant\": \"E\", \"log2 fold change IC90\": -0.017139886299492472, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.08641121923278627, \"functional effect\": -1.3617, \"times_seen\": 2.0}, {\"site\": 361, \"mutant\": \"G\", \"log2 fold change IC90\": 0.12432807956764068, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.0953138986725795, \"functional effect\": -2.1651, \"times_seen\": 4.0}, {\"site\": 361, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03911968301719361, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.08510470189704036, \"functional effect\": -0.5487, \"times_seen\": 24.0}, {\"site\": 361, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013133922845147016, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": 0.08665149262179282, \"functional effect\": -2.0705, \"times_seen\": 3.0}, {\"site\": 361, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"364\", \"IC90\": null, \"functional effect\": -2.4825, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"F\", \"log2 fold change IC90\": -0.12553826526483214, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": 0.08015654129227139, \"functional effect\": 0.3737, \"times_seen\": 28.0}, {\"site\": 362, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -2.6021, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": null, \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 362, \"mutant\": \"S\", \"log2 fold change IC90\": -0.012813406611079438, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": 0.08667074568266103, \"functional effect\": -2.4808, \"times_seen\": 2.0}, {\"site\": 362, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"365\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": null, \"functional effect\": -2.62, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"A\", \"log2 fold change IC90\": 0.10993797529965676, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.09436791964166523, \"functional effect\": -0.4622, \"times_seen\": 7.0}, {\"site\": 363, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": null, \"functional effect\": -2.9689, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"F\", \"log2 fold change IC90\": 0.006716958161151481, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08785202140371111, \"functional effect\": -1.6583, \"times_seen\": 4.0}, {\"site\": 363, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01653140650885391, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08644767223829058, \"functional effect\": -2.019, \"times_seen\": 4.0}, {\"site\": 363, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004973919905985431, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.0871429893215624, \"functional effect\": -1.9635, \"times_seen\": 2.0}, {\"site\": 363, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 363, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0004606157960495445, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08741603292664783, \"functional effect\": 0.0449, \"times_seen\": 1.0}, {\"site\": 363, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009942151890268163, \"epitope\": \"all\", \"reference_site\": \"366\", \"IC90\": 0.08684340974517427, \"functional effect\": -1.8807, \"times_seen\": 2.0}, {\"site\": 364, \"mutant\": \"A\", \"log2 fold change IC90\": 0.08524587888409356, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.09276653161835047, \"functional effect\": -0.138, \"times_seen\": 30.0}, {\"site\": 364, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 364, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02032340664620395, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.08868449714271068, \"functional effect\": -0.7208, \"times_seen\": 3.0}, {\"site\": 364, \"mutant\": \"I\", \"log2 fold change IC90\": 0.725553049464831, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.14459157358414335, \"functional effect\": -0.2354, \"times_seen\": 19.0}, {\"site\": 364, \"mutant\": \"L\", \"log2 fold change IC90\": 0.005048045320552038, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.08775045274818599, \"functional effect\": -0.2734, \"times_seen\": 25.0}, {\"site\": 364, \"mutant\": \"M\", \"log2 fold change IC90\": 0.03385857068295548, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.08952043795778739, \"functional effect\": -0.1391, \"times_seen\": 13.0}, {\"site\": 364, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"367\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": null, \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"F\", \"log2 fold change IC90\": -0.01893123480124109, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.08630399175715321, \"functional effect\": -0.39, \"times_seen\": 13.0}, {\"site\": 365, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": null, \"functional effect\": -3.0169, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"I\", \"log2 fold change IC90\": 0.4999800188733184, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.12366270320781332, \"functional effect\": 0.0653, \"times_seen\": 99.0}, {\"site\": 365, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 365, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0009238098688848712, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": 0.08749995855277312, \"functional effect\": -1.7436, \"times_seen\": 2.0}, {\"site\": 365, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"368\", \"IC90\": null, \"functional effect\": -0.29, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": -2.996, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"C\", \"log2 fold change IC90\": -0.025950375952856465, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.08588511692904514, \"functional effect\": -1.9688, \"times_seen\": 31.0}, {\"site\": 366, \"mutant\": \"F\", \"log2 fold change IC90\": 0.8611132462399538, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.15883663199010303, \"functional effect\": -0.9627, \"times_seen\": 59.0}, {\"site\": 366, \"mutant\": \"H\", \"log2 fold change IC90\": 0.05842594178360589, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.09105791751686243, \"functional effect\": 0.1515, \"times_seen\": 192.0}, {\"site\": 366, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0002093531139222958, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.08745663722859029, \"functional effect\": -0.013, \"times_seen\": 2.0}, {\"site\": 366, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": null, \"functional effect\": -0.7909, \"times_seen\": null}, {\"site\": 366, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"369\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 367, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": null, \"functional effect\": -1.1204, \"times_seen\": null}, {\"site\": 367, \"mutant\": \"D\", \"log2 fold change IC90\": -0.16065752394211497, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.07822886317159501, \"functional effect\": 0.0556, \"times_seen\": 59.0}, {\"site\": 367, \"mutant\": \"H\", \"log2 fold change IC90\": -0.048110144268119444, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.08457600289226368, \"functional effect\": 0.1043, \"times_seen\": 52.0}, {\"site\": 367, \"mutant\": \"K\", \"log2 fold change IC90\": -0.06490782376015185, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.08359697276075274, \"functional effect\": 0.0551, \"times_seen\": 28.0}, {\"site\": 367, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 367, \"mutant\": \"S\", \"log2 fold change IC90\": 0.05590051917053802, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": 0.09089866101162383, \"functional effect\": -0.1012, \"times_seen\": 119.0}, {\"site\": 367, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"370\", \"IC90\": null, \"functional effect\": -2.7039, \"times_seen\": null}, {\"site\": 368, \"mutant\": \"*\", \"log2 fold change IC90\": -0.03774863899614646, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08518561834203293, \"functional effect\": -2.6155, \"times_seen\": 10.0}, {\"site\": 368, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": null, \"functional effect\": -3.1689, \"times_seen\": null}, {\"site\": 368, \"mutant\": \"A\", \"log2 fold change IC90\": -0.14468978187325182, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.079099509133816, \"functional effect\": -0.4914, \"times_seen\": 69.0}, {\"site\": 368, \"mutant\": \"C\", \"log2 fold change IC90\": -0.026536753776154255, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08585021634830213, \"functional effect\": -1.1983, \"times_seen\": 29.0}, {\"site\": 368, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0591415620887433, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.09110309619768239, \"functional effect\": -0.3662, \"times_seen\": 26.0}, {\"site\": 368, \"mutant\": \"E\", \"log2 fold change IC90\": 0.1272452698830156, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.09550682238618585, \"functional effect\": -0.5704, \"times_seen\": 46.0}, {\"site\": 368, \"mutant\": \"F\", \"log2 fold change IC90\": 0.5298603797730482, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.1262506493874212, \"functional effect\": 0.3186, \"times_seen\": 59.0}, {\"site\": 368, \"mutant\": \"G\", \"log2 fold change IC90\": 0.5972691510064102, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.13228959374545649, \"functional effect\": -0.4595, \"times_seen\": 68.0}, {\"site\": 368, \"mutant\": \"H\", \"log2 fold change IC90\": -0.062144509480274626, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08375724646701083, \"functional effect\": -0.1037, \"times_seen\": 49.0}, {\"site\": 368, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06945684645089582, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08333379475067013, \"functional effect\": -0.0442, \"times_seen\": 29.0}, {\"site\": 368, \"mutant\": \"K\", \"log2 fold change IC90\": 1.0856552471129712, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.18558571616476324, \"functional effect\": -0.6695, \"times_seen\": 55.0}, {\"site\": 368, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 368, \"mutant\": \"M\", \"log2 fold change IC90\": 0.2737493056171381, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.10571497346202885, \"functional effect\": 0.0595, \"times_seen\": 69.0}, {\"site\": 368, \"mutant\": \"N\", \"log2 fold change IC90\": 0.6967240931429814, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.14173091913426175, \"functional effect\": -0.284, \"times_seen\": 25.0}, {\"site\": 368, \"mutant\": \"P\", \"log2 fold change IC90\": -0.151593422350963, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.07872190327083854, \"functional effect\": -1.429, \"times_seen\": 156.0}, {\"site\": 368, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.048447916888003116, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08455620375708037, \"functional effect\": -0.2541, \"times_seen\": 84.0}, {\"site\": 368, \"mutant\": \"R\", \"log2 fold change IC90\": 0.3263035293298103, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.10963693926691864, \"functional effect\": -0.63, \"times_seen\": 155.0}, {\"site\": 368, \"mutant\": \"S\", \"log2 fold change IC90\": 1.2925983585954985, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.21421043893109834, \"functional effect\": -0.2365, \"times_seen\": 113.0}, {\"site\": 368, \"mutant\": \"T\", \"log2 fold change IC90\": -0.21488417836474558, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.07534304521623253, \"functional effect\": -0.5176, \"times_seen\": 84.0}, {\"site\": 368, \"mutant\": \"V\", \"log2 fold change IC90\": 0.12266963613771213, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.09520439397235914, \"functional effect\": -0.1334, \"times_seen\": 87.0}, {\"site\": 368, \"mutant\": \"W\", \"log2 fold change IC90\": 0.02095373391859823, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.08872325271409641, \"functional effect\": 0.4396, \"times_seen\": 66.0}, {\"site\": 368, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04897301379813684, \"epitope\": \"all\", \"reference_site\": \"371\", \"IC90\": 0.0845254334827748, \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 369, \"mutant\": \"-\", \"log2 fold change IC90\": -1.3341519008278559e-05, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08744313845020567, \"functional effect\": -0.1683, \"times_seen\": 1.0}, {\"site\": 369, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 369, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0007658864857807414, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08739753786787961, \"functional effect\": -0.1472, \"times_seen\": 2.0}, {\"site\": 369, \"mutant\": \"P\", \"log2 fold change IC90\": 0.055162849467287056, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.09085219516353416, \"functional effect\": -0.4262, \"times_seen\": 29.0}, {\"site\": 369, \"mutant\": \"S\", \"log2 fold change IC90\": 0.006440449991156374, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08783518522334366, \"functional effect\": -0.184, \"times_seen\": 15.0}, {\"site\": 369, \"mutant\": \"T\", \"log2 fold change IC90\": -0.25922764716088437, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.07306248768822675, \"functional effect\": -0.3405, \"times_seen\": 66.0}, {\"site\": 369, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0534167640965353, \"epitope\": \"all\", \"reference_site\": \"372\", \"IC90\": 0.08426548108026391, \"functional effect\": -0.0329, \"times_seen\": 37.0}, {\"site\": 370, \"mutant\": \"*\", \"log2 fold change IC90\": -0.022526597254884526, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08608918003368883, \"functional effect\": -2.9613, \"times_seen\": 2.0}, {\"site\": 370, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": null, \"functional effect\": -0.21, \"times_seen\": null}, {\"site\": 370, \"mutant\": \"A\", \"log2 fold change IC90\": -0.017982025000538693, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.0863607934705496, \"functional effect\": -0.2148, \"times_seen\": 49.0}, {\"site\": 370, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01454040097595174, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.0865670575622401, \"functional effect\": -1.8573, \"times_seen\": 4.0}, {\"site\": 370, \"mutant\": \"D\", \"log2 fold change IC90\": 0.9615722116075343, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.17029105321572904, \"functional effect\": 0.0955, \"times_seen\": 16.0}, {\"site\": 370, \"mutant\": \"E\", \"log2 fold change IC90\": 0.00152106634615969, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08753618986602517, \"functional effect\": 0.0605, \"times_seen\": 20.0}, {\"site\": 370, \"mutant\": \"F\", \"log2 fold change IC90\": -0.5886909174283975, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.058145502554821545, \"functional effect\": -1.1184, \"times_seen\": 17.0}, {\"site\": 370, \"mutant\": \"G\", \"log2 fold change IC90\": 0.444575303082705, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.1190036424365067, \"functional effect\": -0.1726, \"times_seen\": 42.0}, {\"site\": 370, \"mutant\": \"H\", \"log2 fold change IC90\": -3.3451880851716504, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.008604542778002709, \"functional effect\": -0.1823, \"times_seen\": 43.0}, {\"site\": 370, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0006604132961831712, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08748398491678165, \"functional effect\": -1.1776, \"times_seen\": 12.0}, {\"site\": 370, \"mutant\": \"K\", \"log2 fold change IC90\": -0.1467401433921713, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.078987172574431, \"functional effect\": -0.9567, \"times_seen\": 22.0}, {\"site\": 370, \"mutant\": \"L\", \"log2 fold change IC90\": -0.3307428233637281, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.06952904145621956, \"functional effect\": -1.0822, \"times_seen\": 61.0}, {\"site\": 370, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0040140750441855525, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08720098604229103, \"functional effect\": -0.4088, \"times_seen\": 13.0}, {\"site\": 370, \"mutant\": \"N\", \"log2 fold change IC90\": -0.7424528861579534, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.05226719139985757, \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 370, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 370, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.021194803946924308, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08873807934309068, \"functional effect\": -0.1828, \"times_seen\": 29.0}, {\"site\": 370, \"mutant\": \"R\", \"log2 fold change IC90\": 0.7899010959694566, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.1511867308653441, \"functional effect\": -0.9029, \"times_seen\": 68.0}, {\"site\": 370, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01814668772640458, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08635093720033159, \"functional effect\": -0.0398, \"times_seen\": 92.0}, {\"site\": 370, \"mutant\": \"T\", \"log2 fold change IC90\": -0.2387336156935408, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.07410777487240996, \"functional effect\": -0.1946, \"times_seen\": 67.0}, {\"site\": 370, \"mutant\": \"V\", \"log2 fold change IC90\": -0.045438758395175166, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08473275427769932, \"functional effect\": -0.8733, \"times_seen\": 24.0}, {\"site\": 370, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0009682841993400442, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08750265597803901, \"functional effect\": -1.2685, \"times_seen\": 16.0}, {\"site\": 370, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.020426402086405383, \"epitope\": \"all\", \"reference_site\": \"373\", \"IC90\": 0.08869082864355968, \"functional effect\": -0.5623, \"times_seen\": 18.0}, {\"site\": 371, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": null, \"functional effect\": 0.1515, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": null, \"functional effect\": -2.4492, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04076713646320884, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.08995014830764096, \"functional effect\": -0.1664, \"times_seen\": 3.0}, {\"site\": 371, \"mutant\": \"L\", \"log2 fold change IC90\": 1.2713509738989595, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.21107875843058693, \"functional effect\": -0.0949, \"times_seen\": 59.0}, {\"site\": 371, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": null, \"functional effect\": -1.203, \"times_seen\": null}, {\"site\": 371, \"mutant\": \"S\", \"log2 fold change IC90\": 0.07992527106486728, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.0924250420484194, \"functional effect\": -0.1855, \"times_seen\": 17.0}, {\"site\": 371, \"mutant\": \"V\", \"log2 fold change IC90\": -0.028388248087581405, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.08574011044880424, \"functional effect\": -0.222, \"times_seen\": 4.0}, {\"site\": 371, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0277755566414227, \"epitope\": \"all\", \"reference_site\": \"374\", \"IC90\": 0.08914377647211076, \"functional effect\": 0.397, \"times_seen\": 4.0}, {\"site\": 372, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0322258625961238, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08551234210885165, \"functional effect\": -2.2564, \"times_seen\": 7.0}, {\"site\": 372, \"mutant\": \"A\", \"log2 fold change IC90\": 0.4576966553752889, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.12009092085693852, \"functional effect\": 0.1646, \"times_seen\": 82.0}, {\"site\": 372, \"mutant\": \"C\", \"log2 fold change IC90\": -0.49971399993073917, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.06184446680622313, \"functional effect\": -0.0937, \"times_seen\": 58.0}, {\"site\": 372, \"mutant\": \"D\", \"log2 fold change IC90\": 0.13024396277338973, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.09570554316169105, \"functional effect\": 0.4444, \"times_seen\": 48.0}, {\"site\": 372, \"mutant\": \"E\", \"log2 fold change IC90\": 1.055837810383202, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.1817894201163854, \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 372, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 372, \"mutant\": \"G\", \"log2 fold change IC90\": 0.28843323859845654, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.10679644821819713, \"functional effect\": 0.1997, \"times_seen\": 42.0}, {\"site\": 372, \"mutant\": \"H\", \"log2 fold change IC90\": 0.2830841784114817, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.10640121367920359, \"functional effect\": 0.3194, \"times_seen\": 35.0}, {\"site\": 372, \"mutant\": \"I\", \"log2 fold change IC90\": -0.21066174111773836, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.07556388002506631, \"functional effect\": 0.0579, \"times_seen\": 84.0}, {\"site\": 372, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02215735609670871, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.0861112163863702, \"functional effect\": -0.7091, \"times_seen\": 25.0}, {\"site\": 372, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07974508586735728, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08274163338721835, \"functional effect\": 0.2194, \"times_seen\": 153.0}, {\"site\": 372, \"mutant\": \"M\", \"log2 fold change IC90\": -0.028369895364504887, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08574120116754093, \"functional effect\": 0.2135, \"times_seen\": 29.0}, {\"site\": 372, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0569804450824917, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.09096672845894975, \"functional effect\": 0.3347, \"times_seen\": 46.0}, {\"site\": 372, \"mutant\": \"P\", \"log2 fold change IC90\": -1.1198402898573818, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.040236874201404996, \"functional effect\": 0.3061, \"times_seen\": 81.0}, {\"site\": 372, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0041168745779769636, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.08769383351265238, \"functional effect\": 0.397, \"times_seen\": 23.0}, {\"site\": 372, \"mutant\": \"R\", \"log2 fold change IC90\": 0.28617291150201773, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.10662925702661172, \"functional effect\": -1.2678, \"times_seen\": 47.0}, {\"site\": 372, \"mutant\": \"S\", \"log2 fold change IC90\": -0.530228820451579, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.06055011513763797, \"functional effect\": 0.4444, \"times_seen\": 227.0}, {\"site\": 372, \"mutant\": \"T\", \"log2 fold change IC90\": 0.315387214193587, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.10881048962596003, \"functional effect\": 0.4444, \"times_seen\": 106.0}, {\"site\": 372, \"mutant\": \"V\", \"log2 fold change IC90\": 0.4372940850792518, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.11840454939110634, \"functional effect\": -0.0682, \"times_seen\": 71.0}, {\"site\": 372, \"mutant\": \"W\", \"log2 fold change IC90\": -0.15677561898145717, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.07843963948032774, \"functional effect\": -0.1565, \"times_seen\": 26.0}, {\"site\": 372, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.5362575065166532, \"epitope\": \"all\", \"reference_site\": \"375\", \"IC90\": 0.0602976182600886, \"functional effect\": -0.3609, \"times_seen\": 99.0}, {\"site\": 373, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0062357502707450435, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08706680440814586, \"functional effect\": -3.1261, \"times_seen\": 1.0}, {\"site\": 373, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0166697412061292, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08846018533737407, \"functional effect\": -0.6319, \"times_seen\": 46.0}, {\"site\": 373, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": null, \"functional effect\": -2.9734, \"times_seen\": null}, {\"site\": 373, \"mutant\": \"D\", \"log2 fold change IC90\": -0.025079981673774256, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08593694802764308, \"functional effect\": -0.0101, \"times_seen\": 15.0}, {\"site\": 373, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005624254243082179, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08710371608275591, \"functional effect\": 0.1841, \"times_seen\": 3.0}, {\"site\": 373, \"mutant\": \"F\", \"log2 fold change IC90\": -0.05625787416342682, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08409969973286431, \"functional effect\": -0.9247, \"times_seen\": 10.0}, {\"site\": 373, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0778576688374832, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.09229267772586751, \"functional effect\": -0.9607, \"times_seen\": 12.0}, {\"site\": 373, \"mutant\": \"H\", \"log2 fold change IC90\": 0.027047040240712694, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08909877298414424, \"functional effect\": 0.2849, \"times_seen\": 20.0}, {\"site\": 373, \"mutant\": \"I\", \"log2 fold change IC90\": -0.037543696515445944, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08519772027038122, \"functional effect\": -0.0169, \"times_seen\": 114.0}, {\"site\": 373, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03949328830604717, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08987076059504383, \"functional effect\": -0.7514, \"times_seen\": 6.0}, {\"site\": 373, \"mutant\": \"L\", \"log2 fold change IC90\": 0.028863125826838153, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08921100244396798, \"functional effect\": -0.0194, \"times_seen\": 23.0}, {\"site\": 373, \"mutant\": \"M\", \"log2 fold change IC90\": -0.010211123162194408, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08682722045747222, \"functional effect\": -0.1995, \"times_seen\": 10.0}, {\"site\": 373, \"mutant\": \"N\", \"log2 fold change IC90\": -2.576354010159751, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.014661213440089233, \"functional effect\": -0.3342, \"times_seen\": 111.0}, {\"site\": 373, \"mutant\": \"P\", \"log2 fold change IC90\": 0.027311803299915043, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0891151258707847, \"functional effect\": -1.7207, \"times_seen\": 14.0}, {\"site\": 373, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.028996742047872476, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08921926516664447, \"functional effect\": 0.3897, \"times_seen\": 6.0}, {\"site\": 373, \"mutant\": \"R\", \"log2 fold change IC90\": -0.5134707926496894, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.06125755270240413, \"functional effect\": -0.1864, \"times_seen\": 24.0}, {\"site\": 373, \"mutant\": \"S\", \"log2 fold change IC90\": -0.054744371859468996, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08418797332857493, \"functional effect\": -0.1394, \"times_seen\": 128.0}, {\"site\": 373, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 373, \"mutant\": \"V\", \"log2 fold change IC90\": -1.1022569863428417, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.04073027449988464, \"functional effect\": -0.1724, \"times_seen\": 27.0}, {\"site\": 373, \"mutant\": \"W\", \"log2 fold change IC90\": -0.008501751322399227, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08693015833661569, \"functional effect\": -0.169, \"times_seen\": 1.0}, {\"site\": 373, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.011222511420664293, \"epitope\": \"all\", \"reference_site\": \"376\", \"IC90\": 0.08812681314580158, \"functional effect\": -0.0853, \"times_seen\": 16.0}, {\"site\": 374, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 374, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 374, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0053582366036655, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08711977856350613, \"functional effect\": 0.0743, \"times_seen\": 3.0}, {\"site\": 374, \"mutant\": \"L\", \"log2 fold change IC90\": 0.3815456124750574, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.11391644590561088, \"functional effect\": -0.2708, \"times_seen\": 24.0}, {\"site\": 374, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013642404375182623, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08662095746463078, \"functional effect\": 0.0102, \"times_seen\": 5.0}, {\"site\": 374, \"mutant\": \"S\", \"log2 fold change IC90\": 0.008453146410872704, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08795780915389736, \"functional effect\": -1.298, \"times_seen\": 3.0}, {\"site\": 374, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004104771979924593, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": 0.08719550420904978, \"functional effect\": -0.9615, \"times_seen\": 3.0}, {\"site\": 374, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"377\", \"IC90\": null, \"functional effect\": -0.67, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"E\", \"log2 fold change IC90\": 0.026503669653219607, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08906522151606766, \"functional effect\": -0.0918, \"times_seen\": 7.0}, {\"site\": 375, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"M\", \"log2 fold change IC90\": -0.023717377718345516, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08601815253591596, \"functional effect\": -0.7998, \"times_seen\": 3.0}, {\"site\": 375, \"mutant\": \"N\", \"log2 fold change IC90\": -0.13460744985060677, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.0796542353239308, \"functional effect\": -0.2157, \"times_seen\": 42.0}, {\"site\": 375, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 375, \"mutant\": \"R\", \"log2 fold change IC90\": 0.023626921515054907, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08888780153346282, \"functional effect\": 0.1052, \"times_seen\": 9.0}, {\"site\": 375, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006484651617295834, \"epitope\": \"all\", \"reference_site\": \"378\", \"IC90\": 0.08705178448019919, \"functional effect\": -0.2887, \"times_seen\": 1.0}, {\"site\": 376, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -2.9931, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0069549887703424474, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.08702340910358786, \"functional effect\": -2.9496, \"times_seen\": 1.0}, {\"site\": 376, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -2.1907, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00460356722126624, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.08716536257575334, \"functional effect\": -2.2311, \"times_seen\": 1.0}, {\"site\": 376, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -3.2038, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": null, \"functional effect\": -3.2034, \"times_seen\": null}, {\"site\": 376, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008747800525473413, \"epitope\": \"all\", \"reference_site\": \"379\", \"IC90\": 0.08691533380908753, \"functional effect\": -2.8537, \"times_seen\": 3.0}, {\"site\": 377, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": null, \"functional effect\": -2.7142, \"times_seen\": null}, {\"site\": 377, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 377, \"mutant\": \"C\", \"log2 fold change IC90\": -0.08067667201952124, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.08268822218357466, \"functional effect\": -2.5867, \"times_seen\": 3.0}, {\"site\": 377, \"mutant\": \"F\", \"log2 fold change IC90\": 0.3427299660636224, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.11089239238664403, \"functional effect\": -0.1709, \"times_seen\": 15.0}, {\"site\": 377, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004571491500424329, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.08716730056184109, \"functional effect\": -1.3363, \"times_seen\": 1.0}, {\"site\": 377, \"mutant\": \"L\", \"log2 fold change IC90\": 0.027381608598734175, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.08911943784130681, \"functional effect\": -2.6411, \"times_seen\": 1.0}, {\"site\": 377, \"mutant\": \"W\", \"log2 fold change IC90\": -0.22892588650875784, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.0746132906869816, \"functional effect\": 0.0603, \"times_seen\": 12.0}, {\"site\": 377, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"380\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 378, \"mutant\": \"*\", \"log2 fold change IC90\": -0.00027816232099879204, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08742708887895081, \"functional effect\": -2.5781, \"times_seen\": 1.0}, {\"site\": 378, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 378, \"mutant\": \"E\", \"log2 fold change IC90\": 0.008632061166917166, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.0879687178528007, \"functional effect\": -1.9055, \"times_seen\": 6.0}, {\"site\": 378, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 378, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005051513357937999, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08713830257673325, \"functional effect\": -2.6984, \"times_seen\": 1.0}, {\"site\": 378, \"mutant\": \"R\", \"log2 fold change IC90\": 0.008882996986700253, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.0879840200626126, \"functional effect\": -0.2144, \"times_seen\": 34.0}, {\"site\": 378, \"mutant\": \"S\", \"log2 fold change IC90\": -0.027002503280617512, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": 0.08582250554241803, \"functional effect\": -0.8982, \"times_seen\": 7.0}, {\"site\": 378, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"381\", \"IC90\": null, \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 379, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 379, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0011097957259787413, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.0875112393871429, \"functional effect\": -0.689, \"times_seen\": 1.0}, {\"site\": 379, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": null, \"functional effect\": -1.5909, \"times_seen\": null}, {\"site\": 379, \"mutant\": \"L\", \"log2 fold change IC90\": 0.09831040703677203, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.09361040716211667, \"functional effect\": -0.319, \"times_seen\": 43.0}, {\"site\": 379, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0439493045670922, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.09014877129757115, \"functional effect\": -0.8253, \"times_seen\": 10.0}, {\"site\": 379, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"382\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": null, \"functional effect\": -1.8667, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"F\", \"log2 fold change IC90\": -0.011010276635350568, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.0867791374889878, \"functional effect\": -2.9952, \"times_seen\": 2.0}, {\"site\": 380, \"mutant\": \"G\", \"log2 fold change IC90\": -0.014498040046583649, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.086569599412558, \"functional effect\": -0.9598, \"times_seen\": 14.0}, {\"site\": 380, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": null, \"functional effect\": -1.7595, \"times_seen\": null}, {\"site\": 380, \"mutant\": \"N\", \"log2 fold change IC90\": -0.009707701860161821, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.08685752367356027, \"functional effect\": -2.5084, \"times_seen\": 13.0}, {\"site\": 380, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08735374881115959, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.08230640904041209, \"functional effect\": -2.2382, \"times_seen\": 1.0}, {\"site\": 380, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"383\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 381, \"mutant\": \"*\", \"log2 fold change IC90\": -0.012284670990256825, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08670251560468775, \"functional effect\": -2.9398, \"times_seen\": 1.0}, {\"site\": 381, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 381, \"mutant\": \"A\", \"log2 fold change IC90\": -0.050937374555691216, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08441042271965664, \"functional effect\": -0.2093, \"times_seen\": 40.0}, {\"site\": 381, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01605030011801906, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08647650540256438, \"functional effect\": -2.4684, \"times_seen\": 6.0}, {\"site\": 381, \"mutant\": \"D\", \"log2 fold change IC90\": -0.011910499535253943, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08672500532900315, \"functional effect\": -1.3467, \"times_seen\": 2.0}, {\"site\": 381, \"mutant\": \"E\", \"log2 fold change IC90\": -0.013722800281591854, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.0866161305426841, \"functional effect\": -0.2733, \"times_seen\": 8.0}, {\"site\": 381, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0619487212645319, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.09128053484804226, \"functional effect\": 0.1178, \"times_seen\": 16.0}, {\"site\": 381, \"mutant\": \"G\", \"log2 fold change IC90\": -0.09423348226809562, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.081914851459911, \"functional effect\": -0.8031, \"times_seen\": 25.0}, {\"site\": 381, \"mutant\": \"H\", \"log2 fold change IC90\": -0.09702087514346808, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.0817567387369974, \"functional effect\": -0.4325, \"times_seen\": 23.0}, {\"site\": 381, \"mutant\": \"I\", \"log2 fold change IC90\": 0.9886399876905845, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.1735162063759314, \"functional effect\": -0.1563, \"times_seen\": 11.0}, {\"site\": 381, \"mutant\": \"K\", \"log2 fold change IC90\": 0.017185032341588673, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08849178653476997, \"functional effect\": -1.0839, \"times_seen\": 7.0}, {\"site\": 381, \"mutant\": \"L\", \"log2 fold change IC90\": 0.30183756648670745, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.10779333635463499, \"functional effect\": -0.3583, \"times_seen\": 88.0}, {\"site\": 381, \"mutant\": \"M\", \"log2 fold change IC90\": -0.031988766505665345, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08552639657463208, \"functional effect\": -0.248, \"times_seen\": 11.0}, {\"site\": 381, \"mutant\": \"N\", \"log2 fold change IC90\": 0.02356955704904513, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.0888842672453747, \"functional effect\": -0.6528, \"times_seen\": 14.0}, {\"site\": 381, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 381, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.9464598302316616, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.045375033035350516, \"functional effect\": -0.2759, \"times_seen\": 36.0}, {\"site\": 381, \"mutant\": \"R\", \"log2 fold change IC90\": 0.23047993733131605, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.10259144038521044, \"functional effect\": -0.4712, \"times_seen\": 42.0}, {\"site\": 381, \"mutant\": \"S\", \"log2 fold change IC90\": -1.2868745250215332, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.03583784775130889, \"functional effect\": -0.3294, \"times_seen\": 58.0}, {\"site\": 381, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05392081195388412, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08423604560352979, \"functional effect\": -0.6163, \"times_seen\": 48.0}, {\"site\": 381, \"mutant\": \"V\", \"log2 fold change IC90\": 0.06412702220098832, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.0914184618904175, \"functional effect\": -0.2727, \"times_seen\": 19.0}, {\"site\": 381, \"mutant\": \"W\", \"log2 fold change IC90\": 0.017190862315482013, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08849214413345372, \"functional effect\": -0.1322, \"times_seen\": 9.0}, {\"site\": 381, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027470953785538, \"epitope\": \"all\", \"reference_site\": \"384\", \"IC90\": 0.08579464305695524, \"functional effect\": -0.1029, \"times_seen\": 7.0}, {\"site\": 382, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 382, \"mutant\": \"A\", \"log2 fold change IC90\": 0.016531668639569407, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.08845171969492302, \"functional effect\": -0.0781, \"times_seen\": 5.0}, {\"site\": 382, \"mutant\": \"I\", \"log2 fold change IC90\": -0.21771070048027324, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.07519557794164154, \"functional effect\": -0.506, \"times_seen\": 41.0}, {\"site\": 382, \"mutant\": \"M\", \"log2 fold change IC90\": 0.005007029733411505, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.08774795805244062, \"functional effect\": -0.3039, \"times_seen\": 15.0}, {\"site\": 382, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007434513113966127, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.086994488986991, \"functional effect\": 0.2744, \"times_seen\": 49.0}, {\"site\": 382, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 382, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"385\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 383, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 383, \"mutant\": \"E\", \"log2 fold change IC90\": -0.06081707352065344, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08383434768612119, \"functional effect\": -2.2037, \"times_seen\": 2.0}, {\"site\": 383, \"mutant\": \"I\", \"log2 fold change IC90\": 0.006708930528277773, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08785153256733687, \"functional effect\": -1.8361, \"times_seen\": 3.0}, {\"site\": 383, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 383, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005420063760080964, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.0871160450975914, \"functional effect\": -2.1947, \"times_seen\": 1.0}, {\"site\": 383, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0377231272137721, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": 0.08976055839605944, \"functional effect\": -0.5299, \"times_seen\": 10.0}, {\"site\": 383, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"386\", \"IC90\": null, \"functional effect\": -0.8204, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"M\", \"log2 fold change IC90\": -0.011520537484855537, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": 0.08674845036143952, \"functional effect\": -0.9898, \"times_seen\": 4.0}, {\"site\": 384, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -2.9459, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -3.2651, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -3.036, \"times_seen\": null}, {\"site\": 384, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"387\", \"IC90\": null, \"functional effect\": -2.9934, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"A\", \"log2 fold change IC90\": 0.016417923673165056, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.0884447462590976, \"functional effect\": -0.4402, \"times_seen\": 5.0}, {\"site\": 385, \"mutant\": \"D\", \"log2 fold change IC90\": 0.02599238007900975, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.08903366248971883, \"functional effect\": -0.6615, \"times_seen\": 11.0}, {\"site\": 385, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": null, \"functional effect\": -1.1864, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"K\", \"log2 fold change IC90\": -0.009751435540179265, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.08685489072517878, \"functional effect\": -0.2214, \"times_seen\": 2.0}, {\"site\": 385, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 385, \"mutant\": \"S\", \"log2 fold change IC90\": -0.15753538542109294, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": 0.07839834169097415, \"functional effect\": -0.3296, \"times_seen\": 12.0}, {\"site\": 385, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"388\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"A\", \"log2 fold change IC90\": -0.040458617075857115, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.08502575470447604, \"functional effect\": -1.0555, \"times_seen\": 13.0}, {\"site\": 386, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"E\", \"log2 fold change IC90\": 0.5925184794495821, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.131854691851772, \"functional effect\": -0.0239, \"times_seen\": 12.0}, {\"site\": 386, \"mutant\": \"G\", \"log2 fold change IC90\": 0.1852479925682584, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.09942485246675192, \"functional effect\": -0.6202, \"times_seen\": 31.0}, {\"site\": 386, \"mutant\": \"H\", \"log2 fold change IC90\": 0.002612469121472542, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.08760243628959953, \"functional effect\": -1.1265, \"times_seen\": 2.0}, {\"site\": 386, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": null, \"functional effect\": -2.689, \"times_seen\": null}, {\"site\": 386, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02438977730386533, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": 0.08597807123522405, \"functional effect\": -0.9047, \"times_seen\": 16.0}, {\"site\": 386, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"389\", \"IC90\": null, \"functional effect\": -1.8675, \"times_seen\": null}, {\"site\": 387, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 387, \"mutant\": \"F\", \"log2 fold change IC90\": -0.08139120308446321, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08264727889830037, \"functional effect\": -1.0617, \"times_seen\": 5.0}, {\"site\": 387, \"mutant\": \"I\", \"log2 fold change IC90\": -0.024094080860692813, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08599569520613835, \"functional effect\": -0.5978, \"times_seen\": 4.0}, {\"site\": 387, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 387, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03327713528733961, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.0854500530996498, \"functional effect\": -1.0642, \"times_seen\": 18.0}, {\"site\": 387, \"mutant\": \"P\", \"log2 fold change IC90\": 0.022440923390960307, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08881475945383563, \"functional effect\": -2.8832, \"times_seen\": 4.0}, {\"site\": 387, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.01822705013913633, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08855572473532727, \"functional effect\": -0.4952, \"times_seen\": 4.0}, {\"site\": 387, \"mutant\": \"R\", \"log2 fold change IC90\": -0.002913754408287744, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": 0.08726751822019688, \"functional effect\": -1.5243, \"times_seen\": 1.0}, {\"site\": 387, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"390\", \"IC90\": null, \"functional effect\": -3.2571, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -2.9487, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02786964464904271, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.08914959033684776, \"functional effect\": -1.3162, \"times_seen\": 1.0}, {\"site\": 388, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -3.0135, \"times_seen\": null}, {\"site\": 388, \"mutant\": \"M\", \"log2 fold change IC90\": -0.004379069735685386, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.08717892741570225, \"functional effect\": -2.9312, \"times_seen\": 1.0}, {\"site\": 388, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004446977961357011, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": 0.08717482396571534, \"functional effect\": -3.0312, \"times_seen\": 1.0}, {\"site\": 388, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"391\", \"IC90\": null, \"functional effect\": -3.0351, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0060570658905884575, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08707758869797089, \"functional effect\": -1.5699, \"times_seen\": 1.0}, {\"site\": 389, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009926761457260092, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08684433618130326, \"functional effect\": -1.2761, \"times_seen\": 10.0}, {\"site\": 389, \"mutant\": \"S\", \"log2 fold change IC90\": -0.08390534518301436, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08250337734578275, \"functional effect\": -0.9432, \"times_seen\": 4.0}, {\"site\": 389, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": null, \"functional effect\": -1.8995, \"times_seen\": null}, {\"site\": 389, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.002517361877688896, \"epitope\": \"all\", \"reference_site\": \"392\", \"IC90\": 0.08729149899512728, \"functional effect\": -0.1345, \"times_seen\": 1.0}, {\"site\": 390, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 390, \"mutant\": \"A\", \"log2 fold change IC90\": 0.011879890952672736, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.0881669782273951, \"functional effect\": -0.8816, \"times_seen\": 1.0}, {\"site\": 390, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012736293146837652, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08667537844279473, \"functional effect\": -2.7257, \"times_seen\": 5.0}, {\"site\": 390, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": null, \"functional effect\": -2.9133, \"times_seen\": null}, {\"site\": 390, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007251577454421652, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08700552070387806, \"functional effect\": -0.5996, \"times_seen\": 2.0}, {\"site\": 390, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03188909294269667, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.08553230566485523, \"functional effect\": 0.4444, \"times_seen\": 9.0}, {\"site\": 390, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"393\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 391, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 391, \"mutant\": \"D\", \"log2 fold change IC90\": 0.8424207762930586, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.15679191897006706, \"functional effect\": -0.0117, \"times_seen\": 6.0}, {\"site\": 391, \"mutant\": \"H\", \"log2 fold change IC90\": 0.02584416834080488, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.0890245163044858, \"functional effect\": -2.4143, \"times_seen\": 1.0}, {\"site\": 391, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0019156326521029788, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08732791473098706, \"functional effect\": -1.4106, \"times_seen\": 6.0}, {\"site\": 391, \"mutant\": \"K\", \"log2 fold change IC90\": 0.016363611936751805, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.0884414167284671, \"functional effect\": -0.9108, \"times_seen\": 3.0}, {\"site\": 391, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 391, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05042801927390635, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.09055451299102327, \"functional effect\": -0.2401, \"times_seen\": 2.0}, {\"site\": 391, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013572437675899076, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08662515844215816, \"functional effect\": -0.1483, \"times_seen\": 14.0}, {\"site\": 391, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013655546290782299, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08662016841351805, \"functional effect\": -0.0429, \"times_seen\": 7.0}, {\"site\": 391, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02707009968429789, \"epitope\": \"all\", \"reference_site\": \"394\", \"IC90\": 0.08581848448692149, \"functional effect\": -1.3135, \"times_seen\": 9.0}, {\"site\": 392, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 392, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03554918740552879, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08531558658310684, \"functional effect\": -1.6521, \"times_seen\": 4.0}, {\"site\": 392, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": null, \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 392, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03863164897651032, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08513349593612006, \"functional effect\": -0.5212, \"times_seen\": 9.0}, {\"site\": 392, \"mutant\": \"I\", \"log2 fold change IC90\": -0.060390390694844524, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08385914569646877, \"functional effect\": -0.7646, \"times_seen\": 22.0}, {\"site\": 392, \"mutant\": \"L\", \"log2 fold change IC90\": -0.019904928025263037, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.08624576374755925, \"functional effect\": 0.0892, \"times_seen\": 6.0}, {\"site\": 392, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"395\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": null, \"functional effect\": -2.9509, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": null, \"functional effect\": -0.0178, \"times_seen\": null}, {\"site\": 393, \"mutant\": \"D\", \"log2 fold change IC90\": -0.005707953499430841, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08709866282855051, \"functional effect\": -1.234, \"times_seen\": 1.0}, {\"site\": 393, \"mutant\": \"F\", \"log2 fold change IC90\": -0.013848126900125534, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08660860654422409, \"functional effect\": -0.0749, \"times_seen\": 6.0}, {\"site\": 393, \"mutant\": \"H\", \"log2 fold change IC90\": -0.10533775743829767, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.08128678147896208, \"functional effect\": -0.7207, \"times_seen\": 20.0}, {\"site\": 393, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007316380950204344, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.0870016126463154, \"functional effect\": -0.1288, \"times_seen\": 1.0}, {\"site\": 393, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"396\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": null, \"functional effect\": -1.0782, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"D\", \"log2 fold change IC90\": 0.026275978478800453, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08905116604064407, \"functional effect\": -3.0099, \"times_seen\": 1.0}, {\"site\": 394, \"mutant\": \"L\", \"log2 fold change IC90\": 0.015145274775825486, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08836676063208952, \"functional effect\": -0.6754, \"times_seen\": 4.0}, {\"site\": 394, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": null, \"functional effect\": -3.2687, \"times_seen\": null}, {\"site\": 394, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0008316002662739011, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.0873935570599761, \"functional effect\": -1.9101, \"times_seen\": 1.0}, {\"site\": 394, \"mutant\": \"T\", \"log2 fold change IC90\": 0.03770176434014606, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08975922926605329, \"functional effect\": -2.2252, \"times_seen\": 13.0}, {\"site\": 394, \"mutant\": \"V\", \"log2 fold change IC90\": -0.016960039622599708, \"epitope\": \"all\", \"reference_site\": \"397\", \"IC90\": 0.08642199194557931, \"functional effect\": -0.6478, \"times_seen\": 26.0}, {\"site\": 395, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": null, \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 395, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 395, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004294715567778616, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": 0.08718402490385312, \"functional effect\": -2.5021, \"times_seen\": 1.0}, {\"site\": 395, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": null, \"functional effect\": -2.8109, \"times_seen\": null}, {\"site\": 395, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0076688371335130855, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": 0.08698036039960305, \"functional effect\": -2.7401, \"times_seen\": 1.0}, {\"site\": 395, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"398\", \"IC90\": null, \"functional effect\": -3.2346, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -0.8704, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"F\", \"log2 fold change IC90\": 0.009208768259309587, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": 0.08800388975214356, \"functional effect\": -2.0107, \"times_seen\": 1.0}, {\"site\": 396, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -2.4874, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -3.131, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 396, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"399\", \"IC90\": null, \"functional effect\": -3.0019, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"A\", \"log2 fold change IC90\": -0.008678972347643572, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.08691948046973612, \"functional effect\": -2.4528, \"times_seen\": 2.0}, {\"site\": 397, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -2.7856, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -1.7314, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005828784400618092, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.08709136830759107, \"functional effect\": -3.222, \"times_seen\": 1.0}, {\"site\": 397, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -1.5979, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": null, \"functional effect\": -2.223, \"times_seen\": null}, {\"site\": 397, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0002953584188595009, \"epitope\": \"all\", \"reference_site\": \"400\", \"IC90\": 0.08742604680437954, \"functional effect\": -2.9552, \"times_seen\": 1.0}, {\"site\": 398, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": 1.4893, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": 0.0417, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"I\", \"log2 fold change IC90\": -0.10449473493870762, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": 0.08133429436909514, \"functional effect\": -1.2893, \"times_seen\": 18.0}, {\"site\": 398, \"mutant\": \"L\", \"log2 fold change IC90\": 0.012760221344177366, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": 0.08822079400528549, \"functional effect\": -2.3023, \"times_seen\": 8.0}, {\"site\": 398, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": null, \"functional effect\": -2.2593, \"times_seen\": null}, {\"site\": 398, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"401\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"L\", \"log2 fold change IC90\": -0.008412380024209628, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.08693554360621457, \"functional effect\": -1.6759, \"times_seen\": 2.0}, {\"site\": 399, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013193504863406555, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.08664791406633947, \"functional effect\": -1.1369, \"times_seen\": 4.0}, {\"site\": 399, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004527320634054772, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.08716996939622247, \"functional effect\": -2.3826, \"times_seen\": 1.0}, {\"site\": 399, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": null, \"functional effect\": -3.0507, \"times_seen\": null}, {\"site\": 399, \"mutant\": \"V\", \"log2 fold change IC90\": 0.041500611012434754, \"epitope\": \"all\", \"reference_site\": \"402\", \"IC90\": 0.08999589111314227, \"functional effect\": -0.0074, \"times_seen\": 23.0}, {\"site\": 400, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 400, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07625694541363369, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08294192770932533, \"functional effect\": -1.8128, \"times_seen\": 5.0}, {\"site\": 400, \"mutant\": \"I\", \"log2 fold change IC90\": -0.013009297905220249, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08665897819788097, \"functional effect\": -2.0965, \"times_seen\": 4.0}, {\"site\": 400, \"mutant\": \"K\", \"log2 fold change IC90\": 0.146799630336844, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.0968101392727202, \"functional effect\": -0.2878, \"times_seen\": 59.0}, {\"site\": 400, \"mutant\": \"M\", \"log2 fold change IC90\": -0.08749075596235349, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08229859309117882, \"functional effect\": -0.374, \"times_seen\": 23.0}, {\"site\": 400, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 400, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04207256488281278, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08493068929089838, \"functional effect\": -0.4068, \"times_seen\": 7.0}, {\"site\": 400, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0252815339483737, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": 0.08898980454103445, \"functional effect\": -1.9766, \"times_seen\": 1.0}, {\"site\": 400, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"403\", \"IC90\": null, \"functional effect\": -2.3165, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"A\", \"log2 fold change IC90\": 1.5460093485560722, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.2553435783990612, \"functional effect\": -0.7782, \"times_seen\": 3.0}, {\"site\": 401, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": null, \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"E\", \"log2 fold change IC90\": 0.03089860931097456, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.0893369581568322, \"functional effect\": -1.0488, \"times_seen\": 9.0}, {\"site\": 401, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": null, \"functional effect\": -2.8796, \"times_seen\": null}, {\"site\": 401, \"mutant\": \"R\", \"log2 fold change IC90\": 0.06976951146639361, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.09177670650352181, \"functional effect\": -1.5486, \"times_seen\": 18.0}, {\"site\": 401, \"mutant\": \"S\", \"log2 fold change IC90\": 0.056308300025936855, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.09092435734500048, \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 401, \"mutant\": \"V\", \"log2 fold change IC90\": 0.008665967125622506, \"epitope\": \"all\", \"reference_site\": \"404\", \"IC90\": 0.08797078530203954, \"functional effect\": -2.6442, \"times_seen\": 1.0}, {\"site\": 402, \"mutant\": \"*\", \"log2 fold change IC90\": -0.007259344679355413, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08700505228220094, \"functional effect\": -2.8205, \"times_seen\": 2.0}, {\"site\": 402, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 402, \"mutant\": \"A\", \"log2 fold change IC90\": 0.01921316609835498, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08861627534548829, \"functional effect\": 0.1155, \"times_seen\": 32.0}, {\"site\": 402, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01974340575240461, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08625542025239626, \"functional effect\": -1.5414, \"times_seen\": 5.0}, {\"site\": 402, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 402, \"mutant\": \"E\", \"log2 fold change IC90\": -0.03351963875142008, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08543569095670775, \"functional effect\": -0.2703, \"times_seen\": 27.0}, {\"site\": 402, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0022979004214457696, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08758333732575438, \"functional effect\": -1.0143, \"times_seen\": 6.0}, {\"site\": 402, \"mutant\": \"G\", \"log2 fold change IC90\": -0.4013633319808124, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.06620752462622041, \"functional effect\": -0.4299, \"times_seen\": 42.0}, {\"site\": 402, \"mutant\": \"H\", \"log2 fold change IC90\": -0.005057888433641324, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08713791752512326, \"functional effect\": -0.444, \"times_seen\": 19.0}, {\"site\": 402, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012283450768411374, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08670258893712832, \"functional effect\": -0.8464, \"times_seen\": 12.0}, {\"site\": 402, \"mutant\": \"K\", \"log2 fold change IC90\": 0.022391363254859353, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.0888117085000039, \"functional effect\": -1.2485, \"times_seen\": 8.0}, {\"site\": 402, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0029586328398174245, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08762345835082136, \"functional effect\": -0.7652, \"times_seen\": 32.0}, {\"site\": 402, \"mutant\": \"M\", \"log2 fold change IC90\": 0.02782570468404387, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08914687516134956, \"functional effect\": -0.4456, \"times_seen\": 15.0}, {\"site\": 402, \"mutant\": \"N\", \"log2 fold change IC90\": -0.05102970775822708, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.0844050205833525, \"functional effect\": -1.177, \"times_seen\": 24.0}, {\"site\": 402, \"mutant\": \"P\", \"log2 fold change IC90\": -0.014748148886129913, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08655459281397704, \"functional effect\": -2.2208, \"times_seen\": 5.0}, {\"site\": 402, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03074714068532869, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08932757915741556, \"functional effect\": -0.7947, \"times_seen\": 9.0}, {\"site\": 402, \"mutant\": \"R\", \"log2 fold change IC90\": -0.13270322676526689, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.07975944091129748, \"functional effect\": -1.4681, \"times_seen\": 26.0}, {\"site\": 402, \"mutant\": \"S\", \"log2 fold change IC90\": 0.10115619901588979, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.09379524085944677, \"functional effect\": 0.0325, \"times_seen\": 32.0}, {\"site\": 402, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03526413866557828, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08533244496441085, \"functional effect\": -0.4711, \"times_seen\": 15.0}, {\"site\": 402, \"mutant\": \"V\", \"log2 fold change IC90\": 0.07898432883226479, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.09236478103081044, \"functional effect\": -0.6865, \"times_seen\": 18.0}, {\"site\": 402, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004793947936977777, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.08715386083161275, \"functional effect\": -2.549, \"times_seen\": 1.0}, {\"site\": 402, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.1383293438952812, \"epitope\": \"all\", \"reference_site\": \"405\", \"IC90\": 0.07944900654612497, \"functional effect\": -0.8437, \"times_seen\": 34.0}, {\"site\": 403, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -2.9827, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0058828155313544565, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.0878012414861246, \"functional effect\": -2.3349, \"times_seen\": 1.0}, {\"site\": 403, \"mutant\": \"D\", \"log2 fold change IC90\": -0.08539653527399484, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.08241814473921748, \"functional effect\": -1.2607, \"times_seen\": 26.0}, {\"site\": 403, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -2.6011, \"times_seen\": null}, {\"site\": 403, \"mutant\": \"K\", \"log2 fold change IC90\": 0.008322988867282333, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.08794987410480964, \"functional effect\": -3.0059, \"times_seen\": 4.0}, {\"site\": 403, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.9987340230457405, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": 0.17473449591794218, \"functional effect\": -0.2443, \"times_seen\": 35.0}, {\"site\": 403, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"406\", \"IC90\": null, \"functional effect\": -2.6288, \"times_seen\": null}, {\"site\": 404, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 404, \"mutant\": \"A\", \"log2 fold change IC90\": 0.01719616608975654, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.08849246945738355, \"functional effect\": -1.9623, \"times_seen\": 2.0}, {\"site\": 404, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": null, \"functional effect\": -0.0389, \"times_seen\": null}, {\"site\": 404, \"mutant\": \"I\", \"log2 fold change IC90\": -0.11731695859879936, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.08061462336554767, \"functional effect\": -0.1177, \"times_seen\": 44.0}, {\"site\": 404, \"mutant\": \"L\", \"log2 fold change IC90\": 0.9976310423799372, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.17460095756736027, \"functional effect\": 0.0434, \"times_seen\": 34.0}, {\"site\": 404, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00606123797857316, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.08707733688117943, \"functional effect\": -1.3395, \"times_seen\": 10.0}, {\"site\": 404, \"mutant\": \"S\", \"log2 fold change IC90\": 0.003978836009379299, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.08768544327645378, \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 404, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"407\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 405, \"mutant\": \"*\", \"log2 fold change IC90\": 0.026462756734791287, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08906269578029428, \"functional effect\": -2.695, \"times_seen\": 4.0}, {\"site\": 405, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 405, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03522268176493279, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08533489709006525, \"functional effect\": -0.3577, \"times_seen\": 23.0}, {\"site\": 405, \"mutant\": \"C\", \"log2 fold change IC90\": -0.020421039550808723, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08621491559849033, \"functional effect\": -2.5459, \"times_seen\": 4.0}, {\"site\": 405, \"mutant\": \"D\", \"log2 fold change IC90\": -0.030117089849058563, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08563742602895509, \"functional effect\": -0.8467, \"times_seen\": 7.0}, {\"site\": 405, \"mutant\": \"E\", \"log2 fold change IC90\": -0.030692107739545352, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08560330014751891, \"functional effect\": -0.7397, \"times_seen\": 24.0}, {\"site\": 405, \"mutant\": \"F\", \"log2 fold change IC90\": -0.06361962707468599, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08367165066074225, \"functional effect\": -0.5255, \"times_seen\": 20.0}, {\"site\": 405, \"mutant\": \"G\", \"log2 fold change IC90\": 1.30330881579268, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.21580663848051612, \"functional effect\": -0.4055, \"times_seen\": 38.0}, {\"site\": 405, \"mutant\": \"H\", \"log2 fold change IC90\": 0.035047155812913455, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08959422105198987, \"functional effect\": -0.2608, \"times_seen\": 19.0}, {\"site\": 405, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03884338536608706, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08512100227956931, \"functional effect\": -0.5483, \"times_seen\": 89.0}, {\"site\": 405, \"mutant\": \"K\", \"log2 fold change IC90\": -1.5569239485436002, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.02972000946124642, \"functional effect\": -0.4969, \"times_seen\": 63.0}, {\"site\": 405, \"mutant\": \"L\", \"log2 fold change IC90\": -1.2318736977521263, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.037230495727727485, \"functional effect\": -0.9469, \"times_seen\": 36.0}, {\"site\": 405, \"mutant\": \"M\", \"log2 fold change IC90\": 0.009709462582271117, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08803443723014856, \"functional effect\": -0.6264, \"times_seen\": 11.0}, {\"site\": 405, \"mutant\": \"N\", \"log2 fold change IC90\": -0.07588168384153762, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.0829635046646958, \"functional effect\": -0.4278, \"times_seen\": 16.0}, {\"site\": 405, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03337190523075696, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08544444011111546, \"functional effect\": -0.4112, \"times_seen\": 40.0}, {\"site\": 405, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.035889111068981815, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08529548713752313, \"functional effect\": -0.2147, \"times_seen\": 18.0}, {\"site\": 405, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 405, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07540910213991894, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08299068536144365, \"functional effect\": -0.2414, \"times_seen\": 94.0}, {\"site\": 405, \"mutant\": \"T\", \"log2 fold change IC90\": 0.02994704808252802, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08927805343030785, \"functional effect\": -0.3503, \"times_seen\": 68.0}, {\"site\": 405, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0011323301839504573, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.0875126062967748, \"functional effect\": -0.4723, \"times_seen\": 22.0}, {\"site\": 405, \"mutant\": \"W\", \"log2 fold change IC90\": -0.06067528565805268, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08384258731872851, \"functional effect\": -0.2314, \"times_seen\": 8.0}, {\"site\": 405, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.016352587082047364, \"epitope\": \"all\", \"reference_site\": \"408\", \"IC90\": 0.08645838793414297, \"functional effect\": -0.0626, \"times_seen\": 15.0}, {\"site\": 406, \"mutant\": \"*\", \"log2 fold change IC90\": 0.04041141657336367, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08992797237193173, \"functional effect\": -2.9533, \"times_seen\": 1.0}, {\"site\": 406, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 406, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0025577632616203385, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.0875991145371804, \"functional effect\": -1.3489, \"times_seen\": 9.0}, {\"site\": 406, \"mutant\": \"H\", \"log2 fold change IC90\": 0.01097179448861698, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.08811149946977004, \"functional effect\": -2.9692, \"times_seen\": 2.0}, {\"site\": 406, \"mutant\": \"K\", \"log2 fold change IC90\": -0.012161121828274701, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.0867099409312682, \"functional effect\": -2.9548, \"times_seen\": 6.0}, {\"site\": 406, \"mutant\": \"L\", \"log2 fold change IC90\": -0.004371143582304934, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.0871794063772491, \"functional effect\": -2.8838, \"times_seen\": 3.0}, {\"site\": 406, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 406, \"mutant\": \"R\", \"log2 fold change IC90\": 2.3147918777023233, \"epitope\": \"all\", \"reference_site\": \"409\", \"IC90\": 0.435062390433184, \"functional effect\": -2.9451, \"times_seen\": 10.0}, {\"site\": 407, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": null, \"functional effect\": -1.5536, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0023146800761871733, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": 0.08730376329258203, \"functional effect\": -2.8913, \"times_seen\": 1.0}, {\"site\": 407, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": null, \"functional effect\": -2.8579, \"times_seen\": null}, {\"site\": 407, \"mutant\": \"V\", \"log2 fold change IC90\": -0.031191093315641974, \"epitope\": \"all\", \"reference_site\": \"410\", \"IC90\": 0.08557369761560087, \"functional effect\": -0.341, \"times_seen\": 39.0}, {\"site\": 408, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005567103883022071, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.0871071666438207, \"functional effect\": -2.4914, \"times_seen\": 2.0}, {\"site\": 408, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010182970316706098, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08682891482606919, \"functional effect\": -1.9209, \"times_seen\": 2.0}, {\"site\": 408, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": null, \"functional effect\": -0.7117, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": null, \"functional effect\": -2.8117, \"times_seen\": null}, {\"site\": 408, \"mutant\": \"S\", \"log2 fold change IC90\": -0.037291763898713116, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08521259933921131, \"functional effect\": -1.204, \"times_seen\": 27.0}, {\"site\": 408, \"mutant\": \"T\", \"log2 fold change IC90\": -0.01754777428258674, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08638679195266191, \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 408, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0009675113782644521, \"epitope\": \"all\", \"reference_site\": \"411\", \"IC90\": 0.08738532441501548, \"functional effect\": -2.5928, \"times_seen\": 18.0}, {\"site\": 409, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0034461507816294047, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.08723531991269864, \"functional effect\": -2.5839, \"times_seen\": 1.0}, {\"site\": 409, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0024425407584331505, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.08759211861224925, \"functional effect\": -2.9764, \"times_seen\": 1.0}, {\"site\": 409, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -3.0028, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -2.8733, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -1.8136, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": null, \"functional effect\": -2.8789, \"times_seen\": null}, {\"site\": 409, \"mutant\": \"T\", \"log2 fold change IC90\": 0.02073965007578138, \"epitope\": \"all\", \"reference_site\": \"412\", \"IC90\": 0.0887100879043975, \"functional effect\": -2.8876, \"times_seen\": 2.0}, {\"site\": 410, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": null, \"functional effect\": -2.9652, \"times_seen\": null}, {\"site\": 410, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 410, \"mutant\": \"A\", \"log2 fold change IC90\": -0.013957518673047252, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08660203973033107, \"functional effect\": -0.7148, \"times_seen\": 6.0}, {\"site\": 410, \"mutant\": \"E\", \"log2 fold change IC90\": -0.007185757887717421, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08700949021659288, \"functional effect\": -1.6159, \"times_seen\": 4.0}, {\"site\": 410, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 410, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0465731865292646, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08466615292714742, \"functional effect\": -0.2529, \"times_seen\": 12.0}, {\"site\": 410, \"mutant\": \"S\", \"log2 fold change IC90\": -1.77228647279212, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.025598726693528823, \"functional effect\": -2.0003, \"times_seen\": 10.0}, {\"site\": 410, \"mutant\": \"V\", \"log2 fold change IC90\": -0.026117428829800702, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08587517267552033, \"functional effect\": -2.7582, \"times_seen\": 4.0}, {\"site\": 410, \"mutant\": \"W\", \"log2 fold change IC90\": -0.013725198920414891, \"epitope\": \"all\", \"reference_site\": \"413\", \"IC90\": 0.08661598653398177, \"functional effect\": -2.2885, \"times_seen\": 1.0}, {\"site\": 411, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": null, \"functional effect\": -1.4209, \"times_seen\": null}, {\"site\": 411, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 411, \"mutant\": \"E\", \"log2 fold change IC90\": 2.1978353980352674, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.40118448865213774, \"functional effect\": -0.3983, \"times_seen\": 1.0}, {\"site\": 411, \"mutant\": \"H\", \"log2 fold change IC90\": 0.013863858953064087, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.08828830725910743, \"functional effect\": -1.8486, \"times_seen\": 12.0}, {\"site\": 411, \"mutant\": \"K\", \"log2 fold change IC90\": 0.10071642357921287, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.09376665369753583, \"functional effect\": -0.7464, \"times_seen\": 16.0}, {\"site\": 411, \"mutant\": \"L\", \"log2 fold change IC90\": 0.013809864606429844, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.08828500304017989, \"functional effect\": -2.1803, \"times_seen\": 7.0}, {\"site\": 411, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 411, \"mutant\": \"R\", \"log2 fold change IC90\": -0.006694263608774616, \"epitope\": \"all\", \"reference_site\": \"414\", \"IC90\": 0.08703913747450816, \"functional effect\": -0.6686, \"times_seen\": 8.0}, {\"site\": 412, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 412, \"mutant\": \"A\", \"log2 fold change IC90\": 0.13932610613960486, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.09630993504385435, \"functional effect\": -0.1443, \"times_seen\": 11.0}, {\"site\": 412, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04649743678016107, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.08467059850159948, \"functional effect\": -0.4647, \"times_seen\": 16.0}, {\"site\": 412, \"mutant\": \"K\", \"log2 fold change IC90\": 0.11658053382866762, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.09480341689488136, \"functional effect\": -0.1293, \"times_seen\": 4.0}, {\"site\": 412, \"mutant\": \"L\", \"log2 fold change IC90\": -0.012592490457493426, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.0866840183655632, \"functional effect\": -2.1157, \"times_seen\": 2.0}, {\"site\": 412, \"mutant\": \"N\", \"log2 fold change IC90\": -0.20749256735076227, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.07573005394271146, \"functional effect\": -0.3731, \"times_seen\": 48.0}, {\"site\": 412, \"mutant\": \"R\", \"log2 fold change IC90\": 0.040034943465983006, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.0899045086146504, \"functional effect\": -0.043, \"times_seen\": 1.0}, {\"site\": 412, \"mutant\": \"S\", \"log2 fold change IC90\": 1.0935597304872642, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.18660532545764016, \"functional effect\": -0.2426, \"times_seen\": 18.0}, {\"site\": 412, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"415\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -3.0001, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"D\", \"log2 fold change IC90\": 0.005174526452240653, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.08775814617110943, \"functional effect\": -2.4364, \"times_seen\": 5.0}, {\"site\": 413, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -2.8403, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01938959636479496, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.08862711308226555, \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 413, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -1.6747, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0023337931365879725, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": 0.08730260668567583, \"functional effect\": -3.1206, \"times_seen\": 1.0}, {\"site\": 413, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -2.3923, \"times_seen\": null}, {\"site\": 413, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"416\", \"IC90\": null, \"functional effect\": -2.1237, \"times_seen\": null}, {\"site\": 414, \"mutant\": \"*\", \"log2 fold change IC90\": -0.03660764595686008, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08525301626053229, \"functional effect\": -2.6092, \"times_seen\": 5.0}, {\"site\": 414, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": null, \"functional effect\": -2.7518, \"times_seen\": null}, {\"site\": 414, \"mutant\": \"A\", \"log2 fold change IC90\": -0.1392129659715344, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.07940036050549974, \"functional effect\": -0.0135, \"times_seen\": 28.0}, {\"site\": 414, \"mutant\": \"C\", \"log2 fold change IC90\": -0.042217344864087535, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08492216659809863, \"functional effect\": -0.9425, \"times_seen\": 12.0}, {\"site\": 414, \"mutant\": \"D\", \"log2 fold change IC90\": -0.007629095095195856, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08698275648770924, \"functional effect\": -1.1213, \"times_seen\": 10.0}, {\"site\": 414, \"mutant\": \"E\", \"log2 fold change IC90\": -0.006457420827354353, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08705342759337391, \"functional effect\": -0.8444, \"times_seen\": 13.0}, {\"site\": 414, \"mutant\": \"F\", \"log2 fold change IC90\": -0.02093800419477893, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08618402751931555, \"functional effect\": -0.2752, \"times_seen\": 11.0}, {\"site\": 414, \"mutant\": \"G\", \"log2 fold change IC90\": -0.8249247698022004, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.049363125846406244, \"functional effect\": -0.7688, \"times_seen\": 29.0}, {\"site\": 414, \"mutant\": \"H\", \"log2 fold change IC90\": -0.7233500937281682, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.05296386589383403, \"functional effect\": 0.0806, \"times_seen\": 24.0}, {\"site\": 414, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03596575153756609, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08965128583216085, \"functional effect\": 0.171, \"times_seen\": 21.0}, {\"site\": 414, \"mutant\": \"K\", \"log2 fold change IC90\": 0.6206966238976745, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.13445533986815464, \"functional effect\": -0.1677, \"times_seen\": 39.0}, {\"site\": 414, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04387533948140408, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08482462719044286, \"functional effect\": 0.0495, \"times_seen\": 45.0}, {\"site\": 414, \"mutant\": \"M\", \"log2 fold change IC90\": 0.06873201387613995, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.0917107300637058, \"functional effect\": 0.0532, \"times_seen\": 15.0}, {\"site\": 414, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 414, \"mutant\": \"P\", \"log2 fold change IC90\": -0.17311799198025507, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.07755611473339113, \"functional effect\": 0.1462, \"times_seen\": 42.0}, {\"site\": 414, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016706001528899544, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08643721097005405, \"functional effect\": -0.0824, \"times_seen\": 4.0}, {\"site\": 414, \"mutant\": \"R\", \"log2 fold change IC90\": 0.09498766889668366, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.09339505676057672, \"functional effect\": -0.1734, \"times_seen\": 54.0}, {\"site\": 414, \"mutant\": \"S\", \"log2 fold change IC90\": 0.500307372101912, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.1236907659494497, \"functional effect\": -0.2119, \"times_seen\": 40.0}, {\"site\": 414, \"mutant\": \"T\", \"log2 fold change IC90\": 0.037224931589028086, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08972956737165053, \"functional effect\": 0.0517, \"times_seen\": 62.0}, {\"site\": 414, \"mutant\": \"V\", \"log2 fold change IC90\": -0.06693127767745494, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08347980589690984, \"functional effect\": 0.2189, \"times_seen\": 23.0}, {\"site\": 414, \"mutant\": \"W\", \"log2 fold change IC90\": -0.007053090740974324, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.08701749179089951, \"functional effect\": -0.3319, \"times_seen\": 5.0}, {\"site\": 414, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.2994888655985876, \"epitope\": \"all\", \"reference_site\": \"417\", \"IC90\": 0.10761799206762564, \"functional effect\": 0.1926, \"times_seen\": 19.0}, {\"site\": 415, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": -0.6627, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00226255692790469, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": 0.0875811917141646, \"functional effect\": -1.2658, \"times_seen\": 1.0}, {\"site\": 415, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": -1.9397, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": null, \"functional effect\": -2.8834, \"times_seen\": null}, {\"site\": 415, \"mutant\": \"V\", \"log2 fold change IC90\": -0.08020169695767378, \"epitope\": \"all\", \"reference_site\": \"418\", \"IC90\": 0.0827154499123903, \"functional effect\": -0.8129, \"times_seen\": 14.0}, {\"site\": 416, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": null, \"functional effect\": -3.2606, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": null, \"functional effect\": -3.0208, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": null, \"functional effect\": -3.054, \"times_seen\": null}, {\"site\": 416, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005043903820848633, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.08713876219146491, \"functional effect\": -2.7621, \"times_seen\": 1.0}, {\"site\": 416, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013502761221506928, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.08662934219512307, \"functional effect\": -2.4187, \"times_seen\": 4.0}, {\"site\": 416, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0056957947390571416, \"epitope\": \"all\", \"reference_site\": \"419\", \"IC90\": 0.08778986029120883, \"functional effect\": -2.8538, \"times_seen\": 4.0}, {\"site\": 417, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 417, \"mutant\": \"E\", \"log2 fold change IC90\": -0.020335607823792092, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08622002111768179, \"functional effect\": -1.2512, \"times_seen\": 4.0}, {\"site\": 417, \"mutant\": \"G\", \"log2 fold change IC90\": -0.009289154193501582, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.0868827260113862, \"functional effect\": -2.7506, \"times_seen\": 5.0}, {\"site\": 417, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": null, \"functional effect\": -1.248, \"times_seen\": null}, {\"site\": 417, \"mutant\": \"I\", \"log2 fold change IC90\": -0.014305622827025678, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08658114626898114, \"functional effect\": -2.9881, \"times_seen\": 1.0}, {\"site\": 417, \"mutant\": \"N\", \"log2 fold change IC90\": -0.577907554126084, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.05858173694082199, \"functional effect\": -0.0155, \"times_seen\": 29.0}, {\"site\": 417, \"mutant\": \"R\", \"log2 fold change IC90\": 0.014151760913154168, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.08830592769335503, \"functional effect\": -2.0778, \"times_seen\": 5.0}, {\"site\": 417, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.8790810390426013, \"epitope\": \"all\", \"reference_site\": \"420\", \"IC90\": 0.047544467916773255, \"functional effect\": -1.6177, \"times_seen\": 12.0}, {\"site\": 418, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006973274969771849, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08702230608646797, \"functional effect\": -2.9341, \"times_seen\": 1.0}, {\"site\": 418, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": null, \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 418, \"mutant\": \"A\", \"log2 fold change IC90\": 0.03333420413700783, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08948790648593156, \"functional effect\": -2.0424, \"times_seen\": 4.0}, {\"site\": 418, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": null, \"functional effect\": -3.0792, \"times_seen\": null}, {\"site\": 418, \"mutant\": \"F\", \"log2 fold change IC90\": -0.011751205091702232, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08673458155528807, \"functional effect\": -0.3202, \"times_seen\": 14.0}, {\"site\": 418, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01712908786255237, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.08641186601507045, \"functional effect\": -0.9485, \"times_seen\": 10.0}, {\"site\": 418, \"mutant\": \"I\", \"log2 fold change IC90\": -0.020099546285268086, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.0862341300565103, \"functional effect\": -2.8359, \"times_seen\": 6.0}, {\"site\": 418, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": null, \"functional effect\": -0.7687, \"times_seen\": null}, {\"site\": 418, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"421\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": null, \"functional effect\": -2.4243, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": null, \"functional effect\": -1.3291, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": null, \"functional effect\": -3.1359, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 419, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0017729212761788402, \"epitope\": \"all\", \"reference_site\": \"422\", \"IC90\": 0.08755147261449919, \"functional effect\": -0.3505, \"times_seen\": 1.0}, {\"site\": 420, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": null, \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 420, \"mutant\": \"C\", \"log2 fold change IC90\": -0.08290102602592239, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": 0.08256083132445617, \"functional effect\": -0.1813, \"times_seen\": 1.0}, {\"site\": 420, \"mutant\": \"H\", \"log2 fold change IC90\": -0.42599427088255065, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": 0.06508676693591238, \"functional effect\": -2.2681, \"times_seen\": 1.0}, {\"site\": 420, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": null, \"functional effect\": -2.8029, \"times_seen\": null}, {\"site\": 420, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"423\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": null, \"functional effect\": -1.7255, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05661752931491653, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.08407873679924331, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 421, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"N\", \"log2 fold change IC90\": -0.010598855514145187, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.08680388829237352, \"functional effect\": -2.5108, \"times_seen\": 2.0}, {\"site\": 421, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": null, \"functional effect\": -1.4729, \"times_seen\": null}, {\"site\": 421, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01418222544109993, \"epitope\": \"all\", \"reference_site\": \"424\", \"IC90\": 0.08658855209193077, \"functional effect\": -0.928, \"times_seen\": 10.0}, {\"site\": 422, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01984080025923317, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08865483560946091, \"functional effect\": -0.2721, \"times_seen\": 7.0}, {\"site\": 422, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 422, \"mutant\": \"M\", \"log2 fold change IC90\": -0.005557890537715784, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08710772292976113, \"functional effect\": -0.7344, \"times_seen\": 2.0}, {\"site\": 422, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0019220901274518238, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08756052555183072, \"functional effect\": -1.9279, \"times_seen\": 1.0}, {\"site\": 422, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.006074194999778042, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.0870765548324429, \"functional effect\": -0.5957, \"times_seen\": 1.0}, {\"site\": 422, \"mutant\": \"V\", \"log2 fold change IC90\": 0.02355579562198802, \"epitope\": \"all\", \"reference_site\": \"425\", \"IC90\": 0.08888341940955921, \"functional effect\": -0.6278, \"times_seen\": 7.0}, {\"site\": 423, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": null, \"functional effect\": -2.878, \"times_seen\": null}, {\"site\": 423, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": null, \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 423, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 423, \"mutant\": \"S\", \"log2 fold change IC90\": 0.008392636626094106, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": 0.087954120088407, \"functional effect\": -1.765, \"times_seen\": 13.0}, {\"site\": 423, \"mutant\": \"T\", \"log2 fold change IC90\": -0.009086511881603452, \"epitope\": \"all\", \"reference_site\": \"426\", \"IC90\": 0.08689493049847996, \"functional effect\": -2.888, \"times_seen\": 3.0}, {\"site\": 424, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02555420607495874, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08900662537411055, \"functional effect\": -0.6326, \"times_seen\": 7.0}, {\"site\": 424, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 424, \"mutant\": \"E\", \"log2 fold change IC90\": -0.06241628818838834, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08374146954145738, \"functional effect\": -0.1615, \"times_seen\": 9.0}, {\"site\": 424, \"mutant\": \"G\", \"log2 fold change IC90\": -3.6474586010804604, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.00697806974659072, \"functional effect\": -0.5222, \"times_seen\": 16.0}, {\"site\": 424, \"mutant\": \"H\", \"log2 fold change IC90\": -0.017180620695298267, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08640877945236504, \"functional effect\": -0.4526, \"times_seen\": 12.0}, {\"site\": 424, \"mutant\": \"N\", \"log2 fold change IC90\": -0.5214315892851155, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.06092046418049258, \"functional effect\": -0.2103, \"times_seen\": 48.0}, {\"site\": 424, \"mutant\": \"R\", \"log2 fold change IC90\": -0.05299507942453993, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08429011459897592, \"functional effect\": -1.0111, \"times_seen\": 4.0}, {\"site\": 424, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": null, \"functional effect\": -0.5455, \"times_seen\": null}, {\"site\": 424, \"mutant\": \"V\", \"log2 fold change IC90\": -0.012874104151504426, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.08666709931923895, \"functional effect\": -0.4356, \"times_seen\": 2.0}, {\"site\": 424, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.18984647604819802, \"epitope\": \"all\", \"reference_site\": \"427\", \"IC90\": 0.09974226741209505, \"functional effect\": -0.3463, \"times_seen\": 27.0}, {\"site\": 425, \"mutant\": \"A\", \"log2 fold change IC90\": -0.007849403434033767, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08696947470398837, \"functional effect\": -0.3824, \"times_seen\": 5.0}, {\"site\": 425, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 425, \"mutant\": \"E\", \"log2 fold change IC90\": -0.019025375035487388, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.0862983603432397, \"functional effect\": -0.1124, \"times_seen\": 9.0}, {\"site\": 425, \"mutant\": \"G\", \"log2 fold change IC90\": -0.019904036939825006, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08624581701756139, \"functional effect\": -0.96, \"times_seen\": 9.0}, {\"site\": 425, \"mutant\": \"H\", \"log2 fold change IC90\": -0.020773143613302656, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08619387655901682, \"functional effect\": -0.1979, \"times_seen\": 4.0}, {\"site\": 425, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": null, \"functional effect\": -2.5958, \"times_seen\": null}, {\"site\": 425, \"mutant\": \"V\", \"log2 fold change IC90\": -0.015504427384333485, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.08650923172150556, \"functional effect\": -0.2893, \"times_seen\": 4.0}, {\"site\": 425, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0002142809032059967, \"epitope\": \"all\", \"reference_site\": \"428\", \"IC90\": 0.0874569359532712, \"functional effect\": -0.8063, \"times_seen\": 18.0}, {\"site\": 426, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 426, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": null, \"functional effect\": -2.3302, \"times_seen\": null}, {\"site\": 426, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014028597246382979, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.0865977731337015, \"functional effect\": -2.3704, \"times_seen\": 3.0}, {\"site\": 426, \"mutant\": \"S\", \"log2 fold change IC90\": -0.002278047721580142, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.08730598010412444, \"functional effect\": -2.3682, \"times_seen\": 1.0}, {\"site\": 426, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": null, \"functional effect\": -2.9588, \"times_seen\": null}, {\"site\": 426, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005334876997937108, \"epitope\": \"all\", \"reference_site\": \"429\", \"IC90\": 0.08712118918744013, \"functional effect\": -2.1454, \"times_seen\": 1.0}, {\"site\": 427, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02229782421765398, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08880595046232674, \"functional effect\": -1.1343, \"times_seen\": 6.0}, {\"site\": 427, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0739871598008677, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08307252257600278, \"functional effect\": -0.092, \"times_seen\": 30.0}, {\"site\": 427, \"mutant\": \"K\", \"log2 fold change IC90\": 0.01905579280621698, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.08860660935649212, \"functional effect\": -1.7059, \"times_seen\": 1.0}, {\"site\": 427, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0012801216542862467, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.0873663913833113, \"functional effect\": -0.7532, \"times_seen\": 5.0}, {\"site\": 427, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"430\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": null, \"functional effect\": -3.1899, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"D\", \"log2 fold change IC90\": -0.02131654582463487, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": 0.08616141708423566, \"functional effect\": -1.2965, \"times_seen\": 7.0}, {\"site\": 428, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": null, \"functional effect\": -2.9501, \"times_seen\": null}, {\"site\": 428, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005451040322690553, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": 0.08711417462144902, \"functional effect\": -2.9554, \"times_seen\": 1.0}, {\"site\": 428, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"431\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -3.0255, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -3.1227, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -0.53, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": null, \"functional effect\": -2.5367, \"times_seen\": null}, {\"site\": 429, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008095068996673723, \"epitope\": \"all\", \"reference_site\": \"432\", \"IC90\": 0.08793598070390012, \"functional effect\": -2.7205, \"times_seen\": 3.0}, {\"site\": 430, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -2.6833, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -3.0191, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -0.8518, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011093966666915948, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": 0.08677410361980169, \"functional effect\": -1.3058, \"times_seen\": 4.0}, {\"site\": 430, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": null, \"functional effect\": -2.9112, \"times_seen\": null}, {\"site\": 430, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0007446982335372891, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": 0.08739882144800133, \"functional effect\": -2.811, \"times_seen\": 2.0}, {\"site\": 430, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"433\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 431, \"mutant\": \"F\", \"log2 fold change IC90\": -0.021619438597457352, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.08614332945629655, \"functional effect\": -0.0207, \"times_seen\": 1.0}, {\"site\": 431, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 431, \"mutant\": \"L\", \"log2 fold change IC90\": -0.001594033767100524, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.08734738363445142, \"functional effect\": -1.4261, \"times_seen\": 2.0}, {\"site\": 431, \"mutant\": \"M\", \"log2 fold change IC90\": -0.017326128933370384, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.08640006482116457, \"functional effect\": -0.5007, \"times_seen\": 7.0}, {\"site\": 431, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": null, \"functional effect\": -0.9182, \"times_seen\": null}, {\"site\": 431, \"mutant\": \"V\", \"log2 fold change IC90\": -1.3777588004768453, \"epitope\": \"all\", \"reference_site\": \"434\", \"IC90\": 0.03364984182322866, \"functional effect\": -0.4859, \"times_seen\": 15.0}, {\"site\": 432, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 432, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": null, \"functional effect\": -3.0514, \"times_seen\": null}, {\"site\": 432, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 432, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07513258856148418, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.08300659326300339, \"functional effect\": -0.0533, \"times_seen\": 24.0}, {\"site\": 432, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07300985500308282, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.0831288163023514, \"functional effect\": -0.5215, \"times_seen\": 19.0}, {\"site\": 432, \"mutant\": \"V\", \"log2 fold change IC90\": 0.019228180178284267, \"epitope\": \"all\", \"reference_site\": \"435\", \"IC90\": 0.08861719757695548, \"functional effect\": -1.2557, \"times_seen\": 9.0}, {\"site\": 433, \"mutant\": \"*\", \"log2 fold change IC90\": -0.02291658680520621, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": 0.0860659115381177, \"functional effect\": -2.5145, \"times_seen\": 10.0}, {\"site\": 433, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": null, \"functional effect\": -3.1203, \"times_seen\": null}, {\"site\": 433, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": null, \"functional effect\": -3.0454, \"times_seen\": null}, {\"site\": 433, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": null, \"functional effect\": -2.542, \"times_seen\": null}, {\"site\": 433, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03587818556933461, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": 0.08529613308092547, \"functional effect\": -2.0667, \"times_seen\": 22.0}, {\"site\": 433, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"436\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"437\", \"IC90\": null, \"functional effect\": -2.9261, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"437\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00519531954804621, \"epitope\": \"all\", \"reference_site\": \"437\", \"IC90\": 0.08712961716336975, \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"-\", \"log2 fold change IC90\": 2.213302643223662, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.4055087575952486, \"functional effect\": -1.4674, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"A\", \"log2 fold change IC90\": 0.07083692591007175, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.09184463494908303, \"functional effect\": -0.3883, \"times_seen\": 5.0}, {\"site\": 435, \"mutant\": \"C\", \"log2 fold change IC90\": 2.803266766257721, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.6103755593979466, \"functional effect\": -0.1849, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"G\", \"log2 fold change IC90\": -0.019503564697531124, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.08626976098976392, \"functional effect\": -1.9279, \"times_seen\": 2.0}, {\"site\": 435, \"mutant\": \"I\", \"log2 fold change IC90\": 0.033019980971145495, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.08946841788266541, \"functional effect\": -2.7564, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"N\", \"log2 fold change IC90\": 4.325035418205136, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 1.7526497934822765, \"functional effect\": -2.0882, \"times_seen\": 8.0}, {\"site\": 435, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": null, \"functional effect\": -2.9463, \"times_seen\": null}, {\"site\": 435, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 435, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07213492281580422, \"epitope\": \"all\", \"reference_site\": \"438\", \"IC90\": 0.09192730501676365, \"functional effect\": -1.1017, \"times_seen\": 6.0}, {\"site\": 436, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02369935850131909, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08889226465693832, \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0390972281373593, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08510602652260044, \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"F\", \"log2 fold change IC90\": 5.529248181895261, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 4.038306788604535, \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"mutant\": \"G\", \"log2 fold change IC90\": -0.009026114263742443, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08689856838210508, \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"H\", \"log2 fold change IC90\": 0.04950423868283579, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.09049654805535334, \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"I\", \"log2 fold change IC90\": -0.010821018808243226, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08679052222923848, \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"K\", \"log2 fold change IC90\": 3.8470452547120138, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 1.258362504669385, \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"mutant\": \"L\", \"log2 fold change IC90\": 0.07071351777498043, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.09183677889493534, \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0012551886142720204, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08736790128560783, \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": null, \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02755065907233547, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08912988118896957, \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"mutant\": \"R\", \"log2 fold change IC90\": 0.032202891803979956, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08941776062296643, \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"S\", \"log2 fold change IC90\": 5.541826820492644, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 4.0736701108756606, \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"mutant\": \"T\", \"log2 fold change IC90\": 6.1582813479553025, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 6.245355440201202, \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0072266005140835384, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08788306124149466, \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0237781927604733, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 0.08889712219584894, \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"mutant\": \"Y\", \"log2 fold change IC90\": 6.970261657781342, \"epitope\": \"all\", \"reference_site\": \"439\", \"IC90\": 10.964468632299004, \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 437, \"mutant\": \"*\", \"log2 fold change IC90\": -0.6238091472579381, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.05674720657747096, \"functional effect\": -2.7496, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": null, \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 437, \"mutant\": \"A\", \"log2 fold change IC90\": -0.023270287066829133, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08604481366001442, \"functional effect\": 0.028, \"times_seen\": 21.0}, {\"site\": 437, \"mutant\": \"C\", \"log2 fold change IC90\": 0.003105924895205611, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.0876324047308733, \"functional effect\": -2.979, \"times_seen\": 1.0}, {\"site\": 437, \"mutant\": \"D\", \"log2 fold change IC90\": 2.9894788008037936, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.6944684866672269, \"functional effect\": 0.1224, \"times_seen\": 14.0}, {\"site\": 437, \"mutant\": \"E\", \"log2 fold change IC90\": -0.04026884050076018, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08503693999131418, \"functional effect\": 0.3113, \"times_seen\": 15.0}, {\"site\": 437, \"mutant\": \"F\", \"log2 fold change IC90\": 2.9888387296630126, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.6941604446817623, \"functional effect\": -1.206, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03619379131017744, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08527747563482407, \"functional effect\": 0.0017, \"times_seen\": 24.0}, {\"site\": 437, \"mutant\": \"H\", \"log2 fold change IC90\": 0.6376729288722647, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.13604683157019043, \"functional effect\": 0.221, \"times_seen\": 12.0}, {\"site\": 437, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02625081347654811, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08586723343697536, \"functional effect\": -0.8004, \"times_seen\": 13.0}, {\"site\": 437, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 437, \"mutant\": \"L\", \"log2 fold change IC90\": 0.09620916066616056, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.09347416537213306, \"functional effect\": -0.8499, \"times_seen\": 18.0}, {\"site\": 437, \"mutant\": \"M\", \"log2 fold change IC90\": 0.030360313096871174, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.0893036311025891, \"functional effect\": -0.0401, \"times_seen\": 10.0}, {\"site\": 437, \"mutant\": \"N\", \"log2 fold change IC90\": -0.06451847652044215, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08361953653344456, \"functional effect\": 0.2118, \"times_seen\": 36.0}, {\"site\": 437, \"mutant\": \"P\", \"log2 fold change IC90\": 0.053290800775201194, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.0907343813305019, \"functional effect\": -0.534, \"times_seen\": 8.0}, {\"site\": 437, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.01526442689747888, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08837405914045403, \"functional effect\": 0.1906, \"times_seen\": 16.0}, {\"site\": 437, \"mutant\": \"R\", \"log2 fold change IC90\": -0.10491115268853643, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08131082152459533, \"functional effect\": -0.1206, \"times_seen\": 36.0}, {\"site\": 437, \"mutant\": \"S\", \"log2 fold change IC90\": 0.05716244391475074, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.09097820481549392, \"functional effect\": 0.2856, \"times_seen\": 44.0}, {\"site\": 437, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0590315903832547, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08393816552236796, \"functional effect\": 0.0087, \"times_seen\": 29.0}, {\"site\": 437, \"mutant\": \"V\", \"log2 fold change IC90\": 2.2175004178934734, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.40669037479179276, \"functional effect\": -0.4789, \"times_seen\": 13.0}, {\"site\": 437, \"mutant\": \"W\", \"log2 fold change IC90\": 0.010061152593551021, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08805590025965798, \"functional effect\": -1.2464, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03711114900851977, \"epitope\": \"all\", \"reference_site\": \"440\", \"IC90\": 0.08972249085247183, \"functional effect\": -0.2806, \"times_seen\": 16.0}, {\"site\": 438, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": null, \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 438, \"mutant\": \"F\", \"log2 fold change IC90\": 0.03819992185992012, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08979022816359096, \"functional effect\": -0.1303, \"times_seen\": 10.0}, {\"site\": 438, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0012126644791685848, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08737047653476827, \"functional effect\": 0.0594, \"times_seen\": 19.0}, {\"site\": 438, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 438, \"mutant\": \"M\", \"log2 fold change IC90\": -0.007692299159503049, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08697894588106331, \"functional effect\": 0.0273, \"times_seen\": 3.0}, {\"site\": 438, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03855547022766818, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08513799136602573, \"functional effect\": -2.2021, \"times_seen\": 6.0}, {\"site\": 438, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009047875382981168, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08689725764366553, \"functional effect\": -1.4385, \"times_seen\": 1.0}, {\"site\": 438, \"mutant\": \"R\", \"log2 fold change IC90\": -0.014092078887367169, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.08659396273188952, \"functional effect\": -0.74, \"times_seen\": 7.0}, {\"site\": 438, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0033715144749405196, \"epitope\": \"all\", \"reference_site\": \"441\", \"IC90\": 0.0872398330567293, \"functional effect\": 0.3662, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": null, \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"E\", \"log2 fold change IC90\": 0.05384278807982318, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.09076910371306612, \"functional effect\": -1.6793, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": null, \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"N\", \"log2 fold change IC90\": -0.010546833776121166, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.08680701838599983, \"functional effect\": -2.4152, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"V\", \"log2 fold change IC90\": 0.024751569613783934, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": 0.08895712073741892, \"functional effect\": -0.8693, \"times_seen\": 2.0}, {\"site\": 439, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"442\", \"IC90\": null, \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": null, \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"A\", \"log2 fold change IC90\": -0.002670278880078005, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.08728224711126796, \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": null, \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"F\", \"log2 fold change IC90\": 0.03675830137591617, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.08970054962686358, \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"G\", \"log2 fold change IC90\": 2.1010774883651657, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.37516049484852926, \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04130142091505315, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.0899834664132995, \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"N\", \"log2 fold change IC90\": 5.859583950177145, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 5.077387201238935, \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"mutant\": \"R\", \"log2 fold change IC90\": 0.04175741390054018, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.09001191200539259, \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"443\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"E\", \"log2 fold change IC90\": 8.123821886689035, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 24.391798301836115, \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": null, \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"I\", \"log2 fold change IC90\": 7.366101691061194, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 14.426046008744457, \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"L\", \"log2 fold change IC90\": 5.178899796191583, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 3.167626269875059, \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"mutant\": \"M\", \"log2 fold change IC90\": 7.858262212961871, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 20.290950561495805, \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"mutant\": \"N\", \"log2 fold change IC90\": 7.445540117819034, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 15.242656481910643, \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": null, \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"R\", \"log2 fold change IC90\": 4.789496011334319, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 2.4183085779107842, \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"mutant\": \"T\", \"log2 fold change IC90\": 8.833872384036626, \"epitope\": \"all\", \"reference_site\": \"444\", \"IC90\": 39.901600701136324, \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"mutant\": \"A\", \"log2 fold change IC90\": 8.514814359563498, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 31.98484736517459, \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"mutant\": \"E\", \"log2 fold change IC90\": 5.740945197695137, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 4.67655946269194, \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"mutant\": \"F\", \"log2 fold change IC90\": 8.335627994233894, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 28.249047688778372, \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"mutant\": \"G\", \"log2 fold change IC90\": 7.841921394320575, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 20.06241991564582, \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"I\", \"log2 fold change IC90\": 0.09358717070234747, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.09330443737239257, \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"mutant\": \"L\", \"log2 fold change IC90\": 0.14976772617528686, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.09700951443114018, \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"M\", \"log2 fold change IC90\": 2.6144342755552565, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.5354918821211566, \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 442, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"445\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0245847498028031, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.08894683515958672, \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 443, \"mutant\": \"A\", \"log2 fold change IC90\": -0.19066029030120363, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.07661878953120028, \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"mutant\": \"C\", \"log2 fold change IC90\": 0.004369867718249414, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.08770921298169279, \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"mutant\": \"D\", \"log2 fold change IC90\": -1.6127127981913596, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.028592677522301376, \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"mutant\": \"E\", \"log2 fold change IC90\": 4.5361390681175, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 2.0288207444347637, \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"F\", \"log2 fold change IC90\": 4.162283630280364, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 1.565676294192961, \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"mutant\": \"G\", \"log2 fold change IC90\": -1.1017755377292036, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.04074386906144797, \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"mutant\": \"H\", \"log2 fold change IC90\": 2.0249818331259872, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.3558852800224293, \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"mutant\": \"I\", \"log2 fold change IC90\": 6.4426060455085, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 7.605844161420845, \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"mutant\": \"K\", \"log2 fold change IC90\": 4.379075533349271, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 1.8195451711451858, \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"L\", \"log2 fold change IC90\": 4.890657722476938, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 2.5939668748758518, \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"mutant\": \"M\", \"log2 fold change IC90\": 3.418964547860085, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.9352778213238334, \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"mutant\": \"N\", \"log2 fold change IC90\": -1.3114565312183328, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.03523238141995108, \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"mutant\": \"P\", \"log2 fold change IC90\": 8.537671353634359, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 32.4956271746785, \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.030735227084798495, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.08560074166981638, \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"mutant\": \"R\", \"log2 fold change IC90\": 4.547363503877383, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 2.0446669103144517, \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"T\", \"log2 fold change IC90\": 6.25971294090601, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 6.700251617860735, \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"mutant\": \"V\", \"log2 fold change IC90\": 5.773757146355565, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 4.784139575612077, \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"mutant\": \"W\", \"log2 fold change IC90\": 4.310373037574586, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 1.7349274945643867, \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"mutant\": \"Y\", \"log2 fold change IC90\": 5.369083323613819, \"epitope\": \"all\", \"reference_site\": \"446\", \"IC90\": 3.613972823823393, \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 444, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": null, \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": null, \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"D\", \"log2 fold change IC90\": 9.579687128238533, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 66.91183304349033, \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"R\", \"log2 fold change IC90\": 10.085972808762458, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 95.04080446723896, \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"mutant\": \"S\", \"log2 fold change IC90\": 7.789201523428359, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 19.342519958160032, \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"mutant\": \"V\", \"log2 fold change IC90\": 9.634658532441225, \"epitope\": \"all\", \"reference_site\": \"447\", \"IC90\": 69.51058908583003, \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": null, \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"D\", \"log2 fold change IC90\": 4.7649239387728715, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 2.3774685763107026, \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"K\", \"log2 fold change IC90\": 7.129158019168119, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 12.241091956598842, \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": null, \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"S\", \"log2 fold change IC90\": 5.131321742715318, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 3.06486616544783, \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"mutant\": \"T\", \"log2 fold change IC90\": 4.758338021125628, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 2.366640142654217, \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"mutant\": \"Y\", \"log2 fold change IC90\": 5.686795686451821, \"epitope\": \"all\", \"reference_site\": \"448\", \"IC90\": 4.504284707468144, \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 446, \"mutant\": \"*\", \"log2 fold change IC90\": 0.012183609016102746, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08818554120985798, \"functional effect\": -2.6941, \"times_seen\": 1.0}, {\"site\": 446, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": null, \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 446, \"mutant\": \"C\", \"log2 fold change IC90\": -0.044332693541562024, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08479774088533863, \"functional effect\": -0.4238, \"times_seen\": 2.0}, {\"site\": 446, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010220855381550625, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08682663473513906, \"functional effect\": 0.2586, \"times_seen\": 9.0}, {\"site\": 446, \"mutant\": \"F\", \"log2 fold change IC90\": -0.024529183326695476, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.08596976367087383, \"functional effect\": -0.1014, \"times_seen\": 12.0}, {\"site\": 446, \"mutant\": \"H\", \"log2 fold change IC90\": -0.14088016409423734, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.0793086573597568, \"functional effect\": 0.2543, \"times_seen\": 80.0}, {\"site\": 446, \"mutant\": \"N\", \"log2 fold change IC90\": 0.07051087847921457, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.09182388051185157, \"functional effect\": 0.3976, \"times_seen\": 23.0}, {\"site\": 446, \"mutant\": \"S\", \"log2 fold change IC90\": 0.45904604746173083, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.12020329772250608, \"functional effect\": 0.4215, \"times_seen\": 9.0}, {\"site\": 446, \"mutant\": \"V\", \"log2 fold change IC90\": 4.808876378105159, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 2.4510139783175493, \"functional effect\": -0.095, \"times_seen\": 5.0}, {\"site\": 446, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"449\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"D\", \"log2 fold change IC90\": 1.734466761302747, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.2909754003873374, \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"mutant\": \"G\", \"log2 fold change IC90\": 0.21505697067766064, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.10150053976605361, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"H\", \"log2 fold change IC90\": -0.03363618310806934, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.08542878953597155, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"K\", \"log2 fold change IC90\": -1.7883506769358928, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.025315269567767612, \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": null, \"functional effect\": 0.1636, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"S\", \"log2 fold change IC90\": 9.117437800566202, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 48.56820068619466, \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"mutant\": \"T\", \"log2 fold change IC90\": 8.238740919200204, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 26.414226405364555, \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0711393750399033, \"epitope\": \"all\", \"reference_site\": \"450\", \"IC90\": 0.09186389143855943, \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 448, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": -2.5122, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"-\", \"log2 fold change IC90\": 0.08382687083211006, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.09267533303845302, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 448, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": -0.4405, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"H\", \"log2 fold change IC90\": 2.381408728976061, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": 0.4556225519163884, \"functional effect\": -1.0316, \"times_seen\": 30.0}, {\"site\": 448, \"mutant\": \"L\", \"log2 fold change IC90\": 0.09165088043029522, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": 0.09317929429949928, \"functional effect\": -1.5391, \"times_seen\": 5.0}, {\"site\": 448, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": null, \"functional effect\": -2.1395, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"451\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0018917814071573431, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08732935848496376, \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"mutant\": \"-\", \"log2 fold change IC90\": 0.02374385534305202, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.08889500639092822, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 449, \"mutant\": \"A\", \"log2 fold change IC90\": 0.06419890063430286, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.09142301668496856, \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"mutant\": \"C\", \"log2 fold change IC90\": 1.4301288141562267, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.2356358815651516, \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04548010891416987, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08473032570266836, \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"mutant\": \"E\", \"log2 fold change IC90\": -0.026879293969638465, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08582983528502788, \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"F\", \"log2 fold change IC90\": 1.3048662018247632, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.21603972704507854, \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"mutant\": \"G\", \"log2 fold change IC90\": -0.10381486404352658, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08137263223630235, \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"mutant\": \"H\", \"log2 fold change IC90\": -0.05323886839969294, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08427587232048524, \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"mutant\": \"I\", \"log2 fold change IC90\": -0.11298258616843294, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08085718274171586, \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"mutant\": \"K\", \"log2 fold change IC90\": -0.021606885684695744, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08614407899405292, \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"mutant\": \"M\", \"log2 fold change IC90\": 0.1277273571631499, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.09553874203415919, \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"mutant\": \"N\", \"log2 fold change IC90\": -0.05455161759246591, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.0841992221890328, \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"mutant\": \"P\", \"log2 fold change IC90\": 0.14625805920510632, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.09677380467968075, \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"mutant\": \"Q\", \"log2 fold change IC90\": 1.3198180961214607, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.21829037582305374, \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"R\", \"log2 fold change IC90\": 0.2257092158330118, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.10225275006433175, \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"mutant\": \"S\", \"log2 fold change IC90\": 0.9854651203918204, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.1731347777308701, \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"mutant\": \"T\", \"log2 fold change IC90\": 3.455298923627755, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.959131982341697, \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"V\", \"log2 fold change IC90\": -0.029202362221157793, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08569174087469172, \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"mutant\": \"W\", \"log2 fold change IC90\": 0.9280202306637361, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.16637638310554043, \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.028712546880816602, \"epitope\": \"all\", \"reference_site\": \"452\", \"IC90\": 0.08920169167674007, \"functional effect\": 0.1313, \"times_seen\": 22.0}, {\"site\": 450, \"mutant\": \"*\", \"log2 fold change IC90\": 0.005012970439796972, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.08774831938031188, \"functional effect\": -2.3815, \"times_seen\": 1.0}, {\"site\": 450, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0034626043241693235, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.08723432502339651, \"functional effect\": -1.9525, \"times_seen\": 1.0}, {\"site\": 450, \"mutant\": \"F\", \"log2 fold change IC90\": 0.24106729551460274, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.10334708697229962, \"functional effect\": -0.4406, \"times_seen\": 13.0}, {\"site\": 450, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06209539604590917, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.08376009784996467, \"functional effect\": -0.9062, \"times_seen\": 9.0}, {\"site\": 450, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": null, \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 450, \"mutant\": \"R\", \"log2 fold change IC90\": -0.010276727554688721, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.08682327220966068, \"functional effect\": -0.6085, \"times_seen\": 3.0}, {\"site\": 450, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"453\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -3.1241, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"G\", \"log2 fold change IC90\": -0.008535276874909485, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": 0.08692813826470631, \"functional effect\": -3.0722, \"times_seen\": 2.0}, {\"site\": 451, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"K\", \"log2 fold change IC90\": -0.00790213627622303, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": 0.08696629588681612, \"functional effect\": -3.0305, \"times_seen\": 3.0}, {\"site\": 451, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"454\", \"IC90\": null, \"functional effect\": -3.2549, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": null, \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"F\", \"log2 fold change IC90\": -0.013687297501781492, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08661826207510158, \"functional effect\": -0.0855, \"times_seen\": 21.0}, {\"site\": 452, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012226707743677456, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08670599912691945, \"functional effect\": 0.2134, \"times_seen\": 3.0}, {\"site\": 452, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0873701957128619, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08230547074252893, \"functional effect\": 0.1937, \"times_seen\": 17.0}, {\"site\": 452, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": null, \"functional effect\": -0.6037, \"times_seen\": null}, {\"site\": 452, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016362659605201155, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08645778430617615, \"functional effect\": 0.2447, \"times_seen\": 4.0}, {\"site\": 452, \"mutant\": \"S\", \"log2 fold change IC90\": -0.011418607283311413, \"epitope\": \"all\", \"reference_site\": \"455\", \"IC90\": 0.08675457958428368, \"functional effect\": -0.0584, \"times_seen\": 5.0}, {\"site\": 453, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": null, \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": null, \"functional effect\": -3.2691, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012924229433987572, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.08666408819267025, \"functional effect\": -0.306, \"times_seen\": 1.0}, {\"site\": 453, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05032353907347643, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.08444634516724249, \"functional effect\": -0.6037, \"times_seen\": 11.0}, {\"site\": 453, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": null, \"functional effect\": -2.5998, \"times_seen\": null}, {\"site\": 453, \"mutant\": \"V\", \"log2 fold change IC90\": -0.5881887863392351, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.058165743662782765, \"functional effect\": -0.8152, \"times_seen\": 5.0}, {\"site\": 453, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.017720414818191955, \"epitope\": \"all\", \"reference_site\": \"456\", \"IC90\": 0.08637645506973866, \"functional effect\": 0.2206, \"times_seen\": 2.0}, {\"site\": 454, \"mutant\": \"G\", \"log2 fold change IC90\": 0.05727402744999598, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.09098524168886658, \"functional effect\": -2.4922, \"times_seen\": 4.0}, {\"site\": 454, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": null, \"functional effect\": -3.0652, \"times_seen\": null}, {\"site\": 454, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0027418293334887547, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.08727791845599528, \"functional effect\": -3.0332, \"times_seen\": 1.0}, {\"site\": 454, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": null, \"functional effect\": -2.1814, \"times_seen\": null}, {\"site\": 454, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 454, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01987002548600567, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": 0.08865663154265879, \"functional effect\": -3.0393, \"times_seen\": 3.0}, {\"site\": 454, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"457\", \"IC90\": null, \"functional effect\": 0.0537, \"times_seen\": null}, {\"site\": 455, \"mutant\": \"E\", \"log2 fold change IC90\": -0.03504324482066368, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08534551138138644, \"functional effect\": -0.1772, \"times_seen\": 10.0}, {\"site\": 455, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 455, \"mutant\": \"L\", \"log2 fold change IC90\": -0.00022158153111444232, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08743051773301135, \"functional effect\": -0.5111, \"times_seen\": 2.0}, {\"site\": 455, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0014265357899156466, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08753045436864551, \"functional effect\": -0.2319, \"times_seen\": 1.0}, {\"site\": 455, \"mutant\": \"N\", \"log2 fold change IC90\": -0.013679409208613878, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08661873568324019, \"functional effect\": 0.0638, \"times_seen\": 17.0}, {\"site\": 455, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.23109995068731654, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.10263553961028715, \"functional effect\": -0.1467, \"times_seen\": 10.0}, {\"site\": 455, \"mutant\": \"R\", \"log2 fold change IC90\": 0.6166896063407937, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.13408241462245155, \"functional effect\": -0.064, \"times_seen\": 20.0}, {\"site\": 455, \"mutant\": \"S\", \"log2 fold change IC90\": -0.010647463924667526, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08680096367709683, \"functional effect\": 0.3853, \"times_seen\": 5.0}, {\"site\": 455, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0026057509791857243, \"epitope\": \"all\", \"reference_site\": \"458\", \"IC90\": 0.08728615110066891, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 456, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": null, \"functional effect\": -0.2341, \"times_seen\": null}, {\"site\": 456, \"mutant\": \"F\", \"log2 fold change IC90\": -0.025297066935788377, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08592401789282975, \"functional effect\": -0.7345, \"times_seen\": 15.0}, {\"site\": 456, \"mutant\": \"G\", \"log2 fold change IC90\": -0.023893527017065756, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08600765058516231, \"functional effect\": -0.2959, \"times_seen\": 7.0}, {\"site\": 456, \"mutant\": \"I\", \"log2 fold change IC90\": 0.001946304055119229, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08756199516388638, \"functional effect\": -0.5048, \"times_seen\": 2.0}, {\"site\": 456, \"mutant\": \"K\", \"log2 fold change IC90\": 0.06734315018499874, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.0916224838241099, \"functional effect\": -0.3614, \"times_seen\": 5.0}, {\"site\": 456, \"mutant\": \"N\", \"log2 fold change IC90\": 0.03002911045659947, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08928313182676724, \"functional effect\": -0.2345, \"times_seen\": 13.0}, {\"site\": 456, \"mutant\": \"P\", \"log2 fold change IC90\": -0.01020932281011602, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08682732881000683, \"functional effect\": -0.5813, \"times_seen\": 2.0}, {\"site\": 456, \"mutant\": \"R\", \"log2 fold change IC90\": 0.00459020247386538, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.08772260934285316, \"functional effect\": -0.1484, \"times_seen\": 3.0}, {\"site\": 456, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 456, \"mutant\": \"Y\", \"log2 fold change IC90\": -1.478879192053205, \"epitope\": \"all\", \"reference_site\": \"459\", \"IC90\": 0.03137203970957345, \"functional effect\": -0.2011, \"times_seen\": 4.0}, {\"site\": 457, \"mutant\": \"D\", \"log2 fold change IC90\": -0.013854238338825122, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08660823965998754, \"functional effect\": -1.2551, \"times_seen\": 4.0}, {\"site\": 457, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03273075597061733, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.0854824209821999, \"functional effect\": -0.0782, \"times_seen\": 2.0}, {\"site\": 457, \"mutant\": \"K\", \"log2 fold change IC90\": 0.04823707329414775, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.09041709692811266, \"functional effect\": -0.1905, \"times_seen\": 3.0}, {\"site\": 457, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 457, \"mutant\": \"S\", \"log2 fold change IC90\": -2.7687340586124902, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.012830918640355446, \"functional effect\": -0.0494, \"times_seen\": 15.0}, {\"site\": 457, \"mutant\": \"T\", \"log2 fold change IC90\": -0.059258218644614974, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08392498098513625, \"functional effect\": -0.3183, \"times_seen\": 8.0}, {\"site\": 457, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.007400888350446793, \"epitope\": \"all\", \"reference_site\": \"460\", \"IC90\": 0.08789367878255366, \"functional effect\": -0.997, \"times_seen\": 3.0}, {\"site\": 458, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01766039492540051, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.08852094904944173, \"functional effect\": 0.4167, \"times_seen\": 1.0}, {\"site\": 458, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 458, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00352922133608875, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.0872302970370668, \"functional effect\": -1.7193, \"times_seen\": 1.0}, {\"site\": 458, \"mutant\": \"P\", \"log2 fold change IC90\": -0.024144883530005976, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": 0.08599266703052123, \"functional effect\": -3.0553, \"times_seen\": 3.0}, {\"site\": 458, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": null, \"functional effect\": -2.9417, \"times_seen\": null}, {\"site\": 458, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": null, \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 458, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"461\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 459, \"mutant\": \"E\", \"log2 fold change IC90\": -0.07218712600918478, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08317623588191528, \"functional effect\": -0.9144, \"times_seen\": 8.0}, {\"site\": 459, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": null, \"functional effect\": -1.773, \"times_seen\": null}, {\"site\": 459, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02069770927051364, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08619838350486064, \"functional effect\": -2.0544, \"times_seen\": 2.0}, {\"site\": 459, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 459, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.015936299752984443, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.0864833389622651, \"functional effect\": -0.027, \"times_seen\": 3.0}, {\"site\": 459, \"mutant\": \"R\", \"log2 fold change IC90\": -0.07657504729902408, \"epitope\": \"all\", \"reference_site\": \"462\", \"IC90\": 0.08292364174151699, \"functional effect\": 0.245, \"times_seen\": 4.0}, {\"site\": 460, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0048380554036953636, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08715119632030283, \"functional effect\": -3.0357, \"times_seen\": 1.0}, {\"site\": 460, \"mutant\": \"L\", \"log2 fold change IC90\": -0.02456719594193445, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.0859674985404034, \"functional effect\": -3.1966, \"times_seen\": 1.0}, {\"site\": 460, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 460, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0025793809557382763, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08728774655835192, \"functional effect\": -1.6084, \"times_seen\": 1.0}, {\"site\": 460, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": null, \"functional effect\": -3.2747, \"times_seen\": null}, {\"site\": 460, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008609706123701906, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08692365372088066, \"functional effect\": -1.9766, \"times_seen\": 8.0}, {\"site\": 460, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011022317976086162, \"epitope\": \"all\", \"reference_site\": \"463\", \"IC90\": 0.08677841319676187, \"functional effect\": -2.697, \"times_seen\": 2.0}, {\"site\": 461, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 461, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": null, \"functional effect\": -3.2776, \"times_seen\": null}, {\"site\": 461, \"mutant\": \"L\", \"log2 fold change IC90\": 0.027112305540423803, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.0891028037664593, \"functional effect\": -1.2792, \"times_seen\": 12.0}, {\"site\": 461, \"mutant\": \"S\", \"log2 fold change IC90\": 0.020874256597417574, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.08871836513077179, \"functional effect\": -0.6701, \"times_seen\": 1.0}, {\"site\": 461, \"mutant\": \"V\", \"log2 fold change IC90\": -0.003780026636697161, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.08721513380527769, \"functional effect\": -2.6458, \"times_seen\": 1.0}, {\"site\": 461, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.026657610546644183, \"epitope\": \"all\", \"reference_site\": \"464\", \"IC90\": 0.08584302484557792, \"functional effect\": -0.29, \"times_seen\": 1.0}, {\"site\": 462, \"mutant\": \"*\", \"log2 fold change IC90\": -0.002109333129252023, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08731619061552007, \"functional effect\": -2.4968, \"times_seen\": 1.0}, {\"site\": 462, \"mutant\": \"A\", \"log2 fold change IC90\": -0.015959104768678997, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08648197191083801, \"functional effect\": -1.5638, \"times_seen\": 3.0}, {\"site\": 462, \"mutant\": \"D\", \"log2 fold change IC90\": -0.005146994650289847, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08713253572913794, \"functional effect\": -1.4526, \"times_seen\": 16.0}, {\"site\": 462, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 462, \"mutant\": \"G\", \"log2 fold change IC90\": -0.019093337832444712, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.0862942950767551, \"functional effect\": -1.101, \"times_seen\": 9.0}, {\"site\": 462, \"mutant\": \"K\", \"log2 fold change IC90\": -0.017754159704925183, \"epitope\": \"all\", \"reference_site\": \"465\", \"IC90\": 0.08637443473313114, \"functional effect\": -2.4745, \"times_seen\": 2.0}, {\"site\": 463, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0027659732501197844, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08727645784713842, \"functional effect\": -2.7086, \"times_seen\": 2.0}, {\"site\": 463, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0055202281822004364, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08710999695494213, \"functional effect\": -2.6585, \"times_seen\": 1.0}, {\"site\": 463, \"mutant\": \"K\", \"log2 fold change IC90\": 0.012325233728983313, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.0881941985245606, \"functional effect\": -0.9854, \"times_seen\": 6.0}, {\"site\": 463, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05030270761031969, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.08444756451962025, \"functional effect\": -1.8776, \"times_seen\": 8.0}, {\"site\": 463, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 463, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": null, \"functional effect\": -3.1059, \"times_seen\": null}, {\"site\": 463, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"466\", \"IC90\": null, \"functional effect\": -3.0058, \"times_seen\": null}, {\"site\": 464, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 464, \"mutant\": \"E\", \"log2 fold change IC90\": 3.9062011697744356e-05, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.08744631473645101, \"functional effect\": -2.7075, \"times_seen\": 1.0}, {\"site\": 464, \"mutant\": \"G\", \"log2 fold change IC90\": 0.025843593163431117, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.0890244808119695, \"functional effect\": -2.9013, \"times_seen\": 1.0}, {\"site\": 464, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": null, \"functional effect\": -2.9555, \"times_seen\": null}, {\"site\": 464, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0053794190032198, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.08711849943495936, \"functional effect\": -2.6267, \"times_seen\": 1.0}, {\"site\": 464, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004019165818749062, \"epitope\": \"all\", \"reference_site\": \"467\", \"IC90\": 0.0872006783405482, \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 465, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02318113293409032, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08886033970377082, \"functional effect\": -2.1352, \"times_seen\": 2.0}, {\"site\": 465, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 465, \"mutant\": \"L\", \"log2 fold change IC90\": 0.14388227227967465, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.09661457162657278, \"functional effect\": -0.349, \"times_seen\": 5.0}, {\"site\": 465, \"mutant\": \"M\", \"log2 fold change IC90\": 0.023002853946836366, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08884935959214728, \"functional effect\": -0.6158, \"times_seen\": 1.0}, {\"site\": 465, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": null, \"functional effect\": -1.9626, \"times_seen\": null}, {\"site\": 465, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": null, \"functional effect\": -0.5777, \"times_seen\": null}, {\"site\": 465, \"mutant\": \"T\", \"log2 fold change IC90\": 0.027605007236268762, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08913323888862108, \"functional effect\": -0.4385, \"times_seen\": 23.0}, {\"site\": 465, \"mutant\": \"V\", \"log2 fold change IC90\": 0.009676417359219222, \"epitope\": \"all\", \"reference_site\": \"468\", \"IC90\": 0.08803242080656953, \"functional effect\": -0.6714, \"times_seen\": 9.0}, {\"site\": 466, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0045739037702820385, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.0877216183110062, \"functional effect\": -1.8312, \"times_seen\": 6.0}, {\"site\": 466, \"mutant\": \"G\", \"log2 fold change IC90\": -0.1270922959651262, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.08007024539660705, \"functional effect\": -0.6392, \"times_seen\": 12.0}, {\"site\": 466, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": null, \"functional effect\": -2.7969, \"times_seen\": null}, {\"site\": 466, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": null, \"functional effect\": -1.23, \"times_seen\": null}, {\"site\": 466, \"mutant\": \"N\", \"log2 fold change IC90\": -0.08010572280770957, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.08272095267550227, \"functional effect\": -0.7065, \"times_seen\": 31.0}, {\"site\": 466, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0073559203726540415, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.08699922825718268, \"functional effect\": -2.4014, \"times_seen\": 1.0}, {\"site\": 466, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"469\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 467, \"mutant\": \"A\", \"log2 fold change IC90\": -0.013621764173888393, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.08662219673331684, \"functional effect\": -0.3892, \"times_seen\": 6.0}, {\"site\": 467, \"mutant\": \"I\", \"log2 fold change IC90\": 0.13700398291188934, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.09615504184598442, \"functional effect\": -0.5468, \"times_seen\": 43.0}, {\"site\": 467, \"mutant\": \"K\", \"log2 fold change IC90\": 1.2365264403646614, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.20604463071946094, \"functional effect\": -0.5988, \"times_seen\": 5.0}, {\"site\": 467, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02075404119660665, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.08619501784127025, \"functional effect\": 0.0284, \"times_seen\": 33.0}, {\"site\": 467, \"mutant\": \"R\", \"log2 fold change IC90\": 0.012067239233563395, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.08817842832869108, \"functional effect\": 0.3772, \"times_seen\": 7.0}, {\"site\": 467, \"mutant\": \"S\", \"log2 fold change IC90\": 0.004891984176877525, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.08774096100185987, \"functional effect\": -0.8349, \"times_seen\": 6.0}, {\"site\": 467, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"470\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 468, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005032119076893164, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.0871394739927577, \"functional effect\": -2.4359, \"times_seen\": 1.0}, {\"site\": 468, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0067311628162092215, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08703691133937488, \"functional effect\": -0.5909, \"times_seen\": 6.0}, {\"site\": 468, \"mutant\": \"D\", \"log2 fold change IC90\": 0.006697153371083237, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08785081541155794, \"functional effect\": -0.101, \"times_seen\": 12.0}, {\"site\": 468, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 468, \"mutant\": \"G\", \"log2 fold change IC90\": 0.11019663712380338, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.09438484045019495, \"functional effect\": -0.7486, \"times_seen\": 23.0}, {\"site\": 468, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03316009614467139, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08545698554645983, \"functional effect\": -1.4314, \"times_seen\": 13.0}, {\"site\": 468, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.09848310449862388, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08167391697803639, \"functional effect\": -0.2862, \"times_seen\": 41.0}, {\"site\": 468, \"mutant\": \"V\", \"log2 fold change IC90\": 0.020624633673662386, \"epitope\": \"all\", \"reference_site\": \"471\", \"IC90\": 0.08870301592580807, \"functional effect\": -0.6964, \"times_seen\": 6.0}, {\"site\": 469, \"mutant\": \"F\", \"log2 fold change IC90\": 0.07493630968917167, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.09210598043101112, \"functional effect\": -0.9636, \"times_seen\": 4.0}, {\"site\": 469, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 469, \"mutant\": \"L\", \"log2 fold change IC90\": -0.013348631706747943, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08663859768665627, \"functional effect\": 0.1237, \"times_seen\": 5.0}, {\"site\": 469, \"mutant\": \"M\", \"log2 fold change IC90\": 0.002218294851118151, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08757850475270894, \"functional effect\": 0.0321, \"times_seen\": 1.0}, {\"site\": 469, \"mutant\": \"N\", \"log2 fold change IC90\": -0.006886293303468784, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.0870275529149113, \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 469, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": null, \"functional effect\": -0.5576, \"times_seen\": null}, {\"site\": 469, \"mutant\": \"T\", \"log2 fold change IC90\": 0.03687455913665533, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08970777832380336, \"functional effect\": -1.1749, \"times_seen\": 18.0}, {\"site\": 469, \"mutant\": \"V\", \"log2 fold change IC90\": -0.002444809134600939, \"epitope\": \"all\", \"reference_site\": \"472\", \"IC90\": 0.08729588897136753, \"functional effect\": -0.4416, \"times_seen\": 9.0}, {\"site\": 470, \"mutant\": \"*\", \"log2 fold change IC90\": -0.009049888861094034, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.08689713636675025, \"functional effect\": -2.7598, \"times_seen\": 2.0}, {\"site\": 470, \"mutant\": \"C\", \"log2 fold change IC90\": -0.05674262720194921, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.08407144654314937, \"functional effect\": -2.3124, \"times_seen\": 1.0}, {\"site\": 470, \"mutant\": \"F\", \"log2 fold change IC90\": 0.04712212000544214, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.09034724717324653, \"functional effect\": 0.0095, \"times_seen\": 16.0}, {\"site\": 470, \"mutant\": \"H\", \"log2 fold change IC90\": -0.027665610912594032, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.08578306790652991, \"functional effect\": -0.6, \"times_seen\": 7.0}, {\"site\": 470, \"mutant\": \"N\", \"log2 fold change IC90\": -0.003953465043992152, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.08720464957661651, \"functional effect\": -1.6109, \"times_seen\": 1.0}, {\"site\": 470, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"473\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 471, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0001823659775200156, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.08743289431479477, \"functional effect\": -2.3923, \"times_seen\": 1.0}, {\"site\": 471, \"mutant\": \"E\", \"log2 fold change IC90\": 0.6282906341551275, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.13516494738792728, \"functional effect\": -0.3826, \"times_seen\": 6.0}, {\"site\": 471, \"mutant\": \"H\", \"log2 fold change IC90\": -0.3956853943884619, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.06646860746225551, \"functional effect\": -1.3723, \"times_seen\": 11.0}, {\"site\": 471, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0035795402572339507, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.0872272546353339, \"functional effect\": -1.1986, \"times_seen\": 7.0}, {\"site\": 471, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": null, \"functional effect\": -0.8613, \"times_seen\": null}, {\"site\": 471, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 471, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0067950463684117324, \"epitope\": \"all\", \"reference_site\": \"474\", \"IC90\": 0.0878567766654431, \"functional effect\": -1.3102, \"times_seen\": 29.0}, {\"site\": 472, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 472, \"mutant\": \"D\", \"log2 fold change IC90\": 0.021360255156747932, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.08874825659058337, \"functional effect\": -1.0243, \"times_seen\": 9.0}, {\"site\": 472, \"mutant\": \"L\", \"log2 fold change IC90\": -0.013935102335199642, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.08660338534780929, \"functional effect\": -0.6215, \"times_seen\": 4.0}, {\"site\": 472, \"mutant\": \"S\", \"log2 fold change IC90\": -0.22912438143362415, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.07460302563421202, \"functional effect\": -0.4959, \"times_seen\": 19.0}, {\"site\": 472, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06995343567259062, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.08330511540973588, \"functional effect\": -0.6461, \"times_seen\": 23.0}, {\"site\": 472, \"mutant\": \"V\", \"log2 fold change IC90\": -0.13972248778141919, \"epitope\": \"all\", \"reference_site\": \"475\", \"IC90\": 0.07937232334514979, \"functional effect\": -0.1795, \"times_seen\": 17.0}, {\"site\": 473, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03117542217611212, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.08557462715691132, \"functional effect\": -0.5457, \"times_seen\": 7.0}, {\"site\": 473, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0049813362282591705, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.08714254135521245, \"functional effect\": -2.2789, \"times_seen\": 1.0}, {\"site\": 473, \"mutant\": \"D\", \"log2 fold change IC90\": -0.07576931503223887, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.0829699667880386, \"functional effect\": -0.7248, \"times_seen\": 44.0}, {\"site\": 473, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 473, \"mutant\": \"K\", \"log2 fold change IC90\": -0.006949677826918374, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.0870237294604477, \"functional effect\": -2.7481, \"times_seen\": 2.0}, {\"site\": 473, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05442616447778355, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": 0.0842065442589503, \"functional effect\": -0.143, \"times_seen\": 21.0}, {\"site\": 473, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"476\", \"IC90\": null, \"functional effect\": -2.9062, \"times_seen\": null}, {\"site\": 474, \"mutant\": \"*\", \"log2 fold change IC90\": -0.024521618664754833, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.085970214447986, \"functional effect\": -2.7271, \"times_seen\": 1.0}, {\"site\": 474, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0060718322009220725, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08707669744369947, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 474, \"mutant\": \"A\", \"log2 fold change IC90\": -0.023684617004397814, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08602010585800113, \"functional effect\": -0.5291, \"times_seen\": 7.0}, {\"site\": 474, \"mutant\": \"C\", \"log2 fold change IC90\": -0.008728890971000809, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08691647302490486, \"functional effect\": -2.4417, \"times_seen\": 2.0}, {\"site\": 474, \"mutant\": \"D\", \"log2 fold change IC90\": -0.042495948892882926, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08490576855643078, \"functional effect\": 0.3592, \"times_seen\": 13.0}, {\"site\": 474, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": null, \"functional effect\": 0.4453, \"times_seen\": null}, {\"site\": 474, \"mutant\": \"F\", \"log2 fold change IC90\": -0.015130514570719771, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08653165579690827, \"functional effect\": -0.6824, \"times_seen\": 3.0}, {\"site\": 474, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07139460997090241, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08322193965707281, \"functional effect\": -0.3226, \"times_seen\": 16.0}, {\"site\": 474, \"mutant\": \"H\", \"log2 fold change IC90\": -0.028527569822267528, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08573183088603417, \"functional effect\": -0.1796, \"times_seen\": 7.0}, {\"site\": 474, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04881049267308146, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08453495589876599, \"functional effect\": -0.2299, \"times_seen\": 23.0}, {\"site\": 474, \"mutant\": \"K\", \"log2 fold change IC90\": 0.05397514254245734, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.09077743135452676, \"functional effect\": -0.0419, \"times_seen\": 17.0}, {\"site\": 474, \"mutant\": \"L\", \"log2 fold change IC90\": -0.002032209758022325, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.0873208584758726, \"functional effect\": -0.5132, \"times_seen\": 12.0}, {\"site\": 474, \"mutant\": \"M\", \"log2 fold change IC90\": -0.007600608558408662, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08698447401073758, \"functional effect\": -0.5954, \"times_seen\": 5.0}, {\"site\": 474, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 474, \"mutant\": \"P\", \"log2 fold change IC90\": 0.003284369217841274, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08764324449380799, \"functional effect\": 0.1628, \"times_seen\": 19.0}, {\"site\": 474, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.041801597074028696, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.0849466425197246, \"functional effect\": -0.0043, \"times_seen\": 7.0}, {\"site\": 474, \"mutant\": \"R\", \"log2 fold change IC90\": -0.024788819717076135, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08595429340854739, \"functional effect\": -0.5627, \"times_seen\": 18.0}, {\"site\": 474, \"mutant\": \"S\", \"log2 fold change IC90\": -0.6054183533173213, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.05747522347268801, \"functional effect\": -0.0281, \"times_seen\": 46.0}, {\"site\": 474, \"mutant\": \"T\", \"log2 fold change IC90\": -0.09946734687904117, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08161821600628451, \"functional effect\": -0.0542, \"times_seen\": 47.0}, {\"site\": 474, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04246240268997633, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08490774284702862, \"functional effect\": 0.0493, \"times_seen\": 9.0}, {\"site\": 474, \"mutant\": \"W\", \"log2 fold change IC90\": -0.005694706156588351, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08709946260335555, \"functional effect\": -1.0221, \"times_seen\": 1.0}, {\"site\": 474, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06812152494724355, \"epitope\": \"all\", \"reference_site\": \"477\", \"IC90\": 0.08341096207890289, \"functional effect\": -0.9565, \"times_seen\": 11.0}, {\"site\": 475, \"mutant\": \"*\", \"log2 fold change IC90\": -0.024760904113746103, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08595595660770301, \"functional effect\": -3.0352, \"times_seen\": 4.0}, {\"site\": 475, \"mutant\": \"-\", \"log2 fold change IC90\": -0.005954736548613469, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08708376526898427, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 475, \"mutant\": \"A\", \"log2 fold change IC90\": 0.010064438710153131, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08805610083031021, \"functional effect\": -0.1629, \"times_seen\": 17.0}, {\"site\": 475, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006197293788070433, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08706912529203793, \"functional effect\": -2.4135, \"times_seen\": 1.0}, {\"site\": 475, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0037698923243245676, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08767274482497098, \"functional effect\": -0.1663, \"times_seen\": 4.0}, {\"site\": 475, \"mutant\": \"E\", \"log2 fold change IC90\": -2.2811653820080764, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.017989974500678723, \"functional effect\": 0.1619, \"times_seen\": 23.0}, {\"site\": 475, \"mutant\": \"F\", \"log2 fold change IC90\": -0.015544947040501545, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08650680204995308, \"functional effect\": -0.3474, \"times_seen\": 6.0}, {\"site\": 475, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05305291622305873, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08428673552542333, \"functional effect\": -0.5754, \"times_seen\": 15.0}, {\"site\": 475, \"mutant\": \"H\", \"log2 fold change IC90\": -0.039085462528029025, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08510672059051805, \"functional effect\": 0.104, \"times_seen\": 12.0}, {\"site\": 475, \"mutant\": \"I\", \"log2 fold change IC90\": 0.5643689998191171, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.12930691498302394, \"functional effect\": -0.2191, \"times_seen\": 25.0}, {\"site\": 475, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 475, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01286197413523985, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08666782800944309, \"functional effect\": -0.1538, \"times_seen\": 18.0}, {\"site\": 475, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03221078399112826, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08551323586223031, \"functional effect\": -0.2939, \"times_seen\": 20.0}, {\"site\": 475, \"mutant\": \"N\", \"log2 fold change IC90\": -0.01614975085412026, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08647054443683054, \"functional effect\": -0.2213, \"times_seen\": 26.0}, {\"site\": 475, \"mutant\": \"P\", \"log2 fold change IC90\": 0.05387356056385444, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.09077103982603857, \"functional effect\": -2.0058, \"times_seen\": 6.0}, {\"site\": 475, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.014004434125037919, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08829691042769855, \"functional effect\": 0.1862, \"times_seen\": 12.0}, {\"site\": 475, \"mutant\": \"R\", \"log2 fold change IC90\": -0.281952496850621, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.07192064836658885, \"functional effect\": -0.1985, \"times_seen\": 66.0}, {\"site\": 475, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07974189804302573, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.0827418162159355, \"functional effect\": 0.0548, \"times_seen\": 28.0}, {\"site\": 475, \"mutant\": \"T\", \"log2 fold change IC90\": -0.17027763877460694, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.07770895628591835, \"functional effect\": 0.1097, \"times_seen\": 40.0}, {\"site\": 475, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0614767427008832, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08379602337488469, \"functional effect\": 0.084, \"times_seen\": 22.0}, {\"site\": 475, \"mutant\": \"W\", \"log2 fold change IC90\": -0.015176793808786969, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.08652888005099148, \"functional effect\": -1.0061, \"times_seen\": 11.0}, {\"site\": 475, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.11085801315668768, \"epitope\": \"all\", \"reference_site\": \"478\", \"IC90\": 0.09442811930003864, \"functional effect\": -0.1538, \"times_seen\": 11.0}, {\"site\": 476, \"mutant\": \"-\", \"log2 fold change IC90\": -0.018394008576964094, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08633613534950775, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 476, \"mutant\": \"A\", \"log2 fold change IC90\": 0.006282098079624029, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08782554485875745, \"functional effect\": -0.5907, \"times_seen\": 6.0}, {\"site\": 476, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01934138143851675, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08627945971129934, \"functional effect\": -0.8606, \"times_seen\": 19.0}, {\"site\": 476, \"mutant\": \"L\", \"log2 fold change IC90\": -2.8872797517641953, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.011818760762478597, \"functional effect\": -0.9326, \"times_seen\": 15.0}, {\"site\": 476, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": null, \"functional effect\": -0.7712, \"times_seen\": null}, {\"site\": 476, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 476, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05216553378169137, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08433859511758375, \"functional effect\": -0.2531, \"times_seen\": 10.0}, {\"site\": 476, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011770579902575696, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08673341675276068, \"functional effect\": -0.6761, \"times_seen\": 1.0}, {\"site\": 476, \"mutant\": \"S\", \"log2 fold change IC90\": -1.3846675733668372, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.03348908480370474, \"functional effect\": 0.0541, \"times_seen\": 19.0}, {\"site\": 476, \"mutant\": \"T\", \"log2 fold change IC90\": -0.000884994093774123, \"epitope\": \"all\", \"reference_site\": \"479\", \"IC90\": 0.08739032270342106, \"functional effect\": -0.0611, \"times_seen\": 14.0}, {\"site\": 477, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.9991, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"-\", \"log2 fold change IC90\": -0.003673426377912687, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": 0.08722157834072032, \"functional effect\": -0.4715, \"times_seen\": 1.0}, {\"site\": 477, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.5488, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.9173, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": null, \"functional effect\": -2.9774, \"times_seen\": null}, {\"site\": 477, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02559166110775593, \"epitope\": \"all\", \"reference_site\": \"480\", \"IC90\": 0.08900893618079773, \"functional effect\": -2.6892, \"times_seen\": 1.0}, {\"site\": 478, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04167893211056238, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08495386540432397, \"functional effect\": -0.1436, \"times_seen\": 25.0}, {\"site\": 478, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": null, \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 478, \"mutant\": \"H\", \"log2 fold change IC90\": -0.019082706283560655, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08629493100144531, \"functional effect\": -0.2157, \"times_seen\": 10.0}, {\"site\": 478, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01626686662343333, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08646352517564991, \"functional effect\": -2.158, \"times_seen\": 3.0}, {\"site\": 478, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01485573916156361, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08654813816834223, \"functional effect\": -0.2804, \"times_seen\": 70.0}, {\"site\": 478, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 478, \"mutant\": \"S\", \"log2 fold change IC90\": -0.47701311066119734, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.0628252894543068, \"functional effect\": -0.4046, \"times_seen\": 38.0}, {\"site\": 478, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03341199533690044, \"epitope\": \"all\", \"reference_site\": \"481\", \"IC90\": 0.08544206578460666, \"functional effect\": -0.2739, \"times_seen\": 10.0}, {\"site\": 479, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": null, \"functional effect\": -3.0998, \"times_seen\": null}, {\"site\": 479, \"mutant\": \"D\", \"log2 fold change IC90\": -0.4559910281911923, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.06374744392391228, \"functional effect\": -0.4916, \"times_seen\": 36.0}, {\"site\": 479, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0583829430659735, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08397591328327006, \"functional effect\": -0.67, \"times_seen\": 10.0}, {\"site\": 479, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 479, \"mutant\": \"R\", \"log2 fold change IC90\": -0.013756808684904342, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08661408877952648, \"functional effect\": -0.9962, \"times_seen\": 8.0}, {\"site\": 479, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00949387606517902, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08687039801978243, \"functional effect\": -0.7021, \"times_seen\": 30.0}, {\"site\": 479, \"mutant\": \"V\", \"log2 fold change IC90\": -0.08596509092304173, \"epitope\": \"all\", \"reference_site\": \"482\", \"IC90\": 0.08238567074561176, \"functional effect\": -1.8789, \"times_seen\": 17.0}, {\"site\": 480, \"mutant\": \"A\", \"log2 fold change IC90\": 0.07391924737175494, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.09204107100323454, \"functional effect\": -0.1605, \"times_seen\": 4.0}, {\"site\": 480, \"mutant\": \"E\", \"log2 fold change IC90\": 0.02209556634617842, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08879350123154757, \"functional effect\": -0.1194, \"times_seen\": 2.0}, {\"site\": 480, \"mutant\": \"F\", \"log2 fold change IC90\": -0.022574217636097096, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08608633845470201, \"functional effect\": -0.843, \"times_seen\": 17.0}, {\"site\": 480, \"mutant\": \"G\", \"log2 fold change IC90\": -0.019982930047671446, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08624110083409117, \"functional effect\": -0.3308, \"times_seen\": 7.0}, {\"site\": 480, \"mutant\": \"I\", \"log2 fold change IC90\": 0.022044197835163537, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08879033971188122, \"functional effect\": 0.0897, \"times_seen\": 17.0}, {\"site\": 480, \"mutant\": \"L\", \"log2 fold change IC90\": -0.1600654158616936, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.07826097629825281, \"functional effect\": -0.1138, \"times_seen\": 31.0}, {\"site\": 480, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0018347329181885284, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.08733281181800093, \"functional effect\": 0.042, \"times_seen\": 8.0}, {\"site\": 480, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"483\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 481, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005277389440548178, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08712466080410754, \"functional effect\": -2.7147, \"times_seen\": 1.0}, {\"site\": 481, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 481, \"mutant\": \"C\", \"log2 fold change IC90\": 0.023136727967572518, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.088857604697707, \"functional effect\": -2.9819, \"times_seen\": 4.0}, {\"site\": 481, \"mutant\": \"D\", \"log2 fold change IC90\": 0.03156349237325281, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08937813963872088, \"functional effect\": -1.4618, \"times_seen\": 36.0}, {\"site\": 481, \"mutant\": \"E\", \"log2 fold change IC90\": 0.18827574004308437, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09963373199019168, \"functional effect\": -0.2489, \"times_seen\": 20.0}, {\"site\": 481, \"mutant\": \"F\", \"log2 fold change IC90\": -0.06167689056311249, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08378439899749207, \"functional effect\": -0.8377, \"times_seen\": 14.0}, {\"site\": 481, \"mutant\": \"G\", \"log2 fold change IC90\": -0.24188480621862368, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.07394608244481084, \"functional effect\": -0.696, \"times_seen\": 50.0}, {\"site\": 481, \"mutant\": \"H\", \"log2 fold change IC90\": 0.09599338922430169, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09346018629361214, \"functional effect\": -0.6341, \"times_seen\": 14.0}, {\"site\": 481, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04343490548246634, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08485052687954173, \"functional effect\": -0.1683, \"times_seen\": 10.0}, {\"site\": 481, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0643474688787355, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08362944883428482, \"functional effect\": -0.3417, \"times_seen\": 18.0}, {\"site\": 481, \"mutant\": \"L\", \"log2 fold change IC90\": -0.09781164289662372, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08171193864001891, \"functional effect\": -0.1515, \"times_seen\": 32.0}, {\"site\": 481, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0060491534077305315, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08707806627763795, \"functional effect\": -0.3964, \"times_seen\": 5.0}, {\"site\": 481, \"mutant\": \"N\", \"log2 fold change IC90\": -0.08370679043556259, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08251473287422756, \"functional effect\": -0.7223, \"times_seen\": 19.0}, {\"site\": 481, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02142772234097846, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08875240697220528, \"functional effect\": 0.0548, \"times_seen\": 56.0}, {\"site\": 481, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05697102092053414, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.0909661342360839, \"functional effect\": -0.136, \"times_seen\": 18.0}, {\"site\": 481, \"mutant\": \"R\", \"log2 fold change IC90\": 0.10691008622356012, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09417007051378617, \"functional effect\": -0.2489, \"times_seen\": 33.0}, {\"site\": 481, \"mutant\": \"S\", \"log2 fold change IC90\": -0.25490292191798564, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.0732818335958987, \"functional effect\": -0.2204, \"times_seen\": 55.0}, {\"site\": 481, \"mutant\": \"T\", \"log2 fold change IC90\": 0.08339299036241388, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.09264746576917327, \"functional effect\": 0.0389, \"times_seen\": 84.0}, {\"site\": 481, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01114124588946818, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08677125995234808, \"functional effect\": -0.0617, \"times_seen\": 67.0}, {\"site\": 481, \"mutant\": \"W\", \"log2 fold change IC90\": -0.017133633455431035, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08641159375202603, \"functional effect\": -2.5984, \"times_seen\": 4.0}, {\"site\": 481, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.015925929174978513, \"epitope\": \"all\", \"reference_site\": \"484\", \"IC90\": 0.08841458956732626, \"functional effect\": -1.1779, \"times_seen\": 13.0}, {\"site\": 482, \"mutant\": \"A\", \"log2 fold change IC90\": -0.08267128513897953, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.0825739797088328, \"functional effect\": -0.7599, \"times_seen\": 32.0}, {\"site\": 482, \"mutant\": \"C\", \"log2 fold change IC90\": -0.003991418678299559, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.08720235547443193, \"functional effect\": -1.7725, \"times_seen\": 1.0}, {\"site\": 482, \"mutant\": \"D\", \"log2 fold change IC90\": 0.5004356004430417, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.12370176021099404, \"functional effect\": -0.4621, \"times_seen\": 34.0}, {\"site\": 482, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 482, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03494968092222409, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.08535104652046617, \"functional effect\": -1.2887, \"times_seen\": 11.0}, {\"site\": 482, \"mutant\": \"S\", \"log2 fold change IC90\": -0.19064770976572593, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.0766194576624237, \"functional effect\": -0.1985, \"times_seen\": 40.0}, {\"site\": 482, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004571859750403926, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.08716727831226537, \"functional effect\": -0.7847, \"times_seen\": 1.0}, {\"site\": 482, \"mutant\": \"V\", \"log2 fold change IC90\": 0.07337710601694084, \"epitope\": \"all\", \"reference_site\": \"485\", \"IC90\": 0.09200648996217947, \"functional effect\": -1.5063, \"times_seen\": 11.0}, {\"site\": 483, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 483, \"mutant\": \"I\", \"log2 fold change IC90\": -0.10479525387445372, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.08131735388664076, \"functional effect\": 0.0929, \"times_seen\": 15.0}, {\"site\": 483, \"mutant\": \"L\", \"log2 fold change IC90\": -1.5116064763397175, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.030668381836985163, \"functional effect\": 0.1442, \"times_seen\": 15.0}, {\"site\": 483, \"mutant\": \"S\", \"log2 fold change IC90\": -0.28900051097661866, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.07157015046610199, \"functional effect\": 0.1937, \"times_seen\": 40.0}, {\"site\": 483, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05725323918049198, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": 0.08404169646387381, \"functional effect\": -0.0454, \"times_seen\": 9.0}, {\"site\": 483, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"486\", \"IC90\": null, \"functional effect\": -0.1748, \"times_seen\": null}, {\"site\": 484, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0045234807679026484, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08717020140745903, \"functional effect\": 0.3125, \"times_seen\": 1.0}, {\"site\": 484, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": null, \"functional effect\": -1.0748, \"times_seen\": null}, {\"site\": 484, \"mutant\": \"I\", \"log2 fold change IC90\": -0.013561801897836071, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08662579705900361, \"functional effect\": -2.8443, \"times_seen\": 3.0}, {\"site\": 484, \"mutant\": \"K\", \"log2 fold change IC90\": -0.027538552658896646, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08579062316004343, \"functional effect\": -0.32, \"times_seen\": 7.0}, {\"site\": 484, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 484, \"mutant\": \"S\", \"log2 fold change IC90\": 0.015375141950069109, \"epitope\": \"all\", \"reference_site\": \"487\", \"IC90\": 0.08838084138740965, \"functional effect\": -0.3665, \"times_seen\": 3.0}, {\"site\": 485, \"mutant\": \"*\", \"log2 fold change IC90\": -0.03351623816628533, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08543589233792472, \"functional effect\": -2.9821, \"times_seen\": 2.0}, {\"site\": 485, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": -2.7516, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": -2.951, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"L\", \"log2 fold change IC90\": -2.4117154946768466, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.016433537036384165, \"functional effect\": -3.08, \"times_seen\": 1.0}, {\"site\": 485, \"mutant\": \"R\", \"log2 fold change IC90\": -0.032758612304018525, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08548077045747882, \"functional effect\": -2.961, \"times_seen\": 3.0}, {\"site\": 485, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": 0.2729, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": null, \"functional effect\": -2.9789, \"times_seen\": null}, {\"site\": 485, \"mutant\": \"W\", \"log2 fold change IC90\": -0.024526825177342008, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08596990419239955, \"functional effect\": -2.8571, \"times_seen\": 1.0}, {\"site\": 485, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0410099513034599, \"epitope\": \"all\", \"reference_site\": \"488\", \"IC90\": 0.08499326783002603, \"functional effect\": -2.3412, \"times_seen\": 4.0}, {\"site\": 486, \"mutant\": \"*\", \"log2 fold change IC90\": -0.014430895513742386, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.0865736285458205, \"functional effect\": -2.3672, \"times_seen\": 1.0}, {\"site\": 486, \"mutant\": \"C\", \"log2 fold change IC90\": -0.06983275938726445, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08331208387642486, \"functional effect\": -1.0498, \"times_seen\": 1.0}, {\"site\": 486, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01460714214639815, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.0865630529369088, \"functional effect\": -1.714, \"times_seen\": 1.0}, {\"site\": 486, \"mutant\": \"H\", \"log2 fold change IC90\": -1.7435414395332731, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.02611388461520928, \"functional effect\": -0.2363, \"times_seen\": 37.0}, {\"site\": 486, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01396577262149371, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08660154426406394, \"functional effect\": -0.4084, \"times_seen\": 2.0}, {\"site\": 486, \"mutant\": \"W\", \"log2 fold change IC90\": -0.05721082766051847, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.08404416710969904, \"functional effect\": -0.3635, \"times_seen\": 4.0}, {\"site\": 486, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"489\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": null, \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 487, \"mutant\": \"I\", \"log2 fold change IC90\": 0.014210026215743446, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.0883094941265586, \"functional effect\": -0.5613, \"times_seen\": 3.0}, {\"site\": 487, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04283939327579677, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08488555850662151, \"functional effect\": -0.6844, \"times_seen\": 10.0}, {\"site\": 487, \"mutant\": \"R\", \"log2 fold change IC90\": -0.008019993294062399, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08695919170377628, \"functional effect\": -2.5252, \"times_seen\": 2.0}, {\"site\": 487, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008407775048884259, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08693582109845013, \"functional effect\": -0.2581, \"times_seen\": 6.0}, {\"site\": 487, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0150698246566386, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08653529600434501, \"functional effect\": -0.0441, \"times_seen\": 2.0}, {\"site\": 487, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0012498280597898002, \"epitope\": \"all\", \"reference_site\": \"490\", \"IC90\": 0.08751973390433654, \"functional effect\": 0.0991, \"times_seen\": 11.0}, {\"site\": 488, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": null, \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 488, \"mutant\": \"L\", \"log2 fold change IC90\": -0.02209571758619343, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.08611489552877653, \"functional effect\": -1.8109, \"times_seen\": 3.0}, {\"site\": 488, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 488, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": null, \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 488, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0054541213303274765, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.08711398858133446, \"functional effect\": -3.0999, \"times_seen\": 1.0}, {\"site\": 488, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004437591261361922, \"epitope\": \"all\", \"reference_site\": \"491\", \"IC90\": 0.08717539115875235, \"functional effect\": -2.9169, \"times_seen\": 1.0}, {\"site\": 489, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -2.2894, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"F\", \"log2 fold change IC90\": -0.024950419894945796, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.08594466597461452, \"functional effect\": -2.4022, \"times_seen\": 4.0}, {\"site\": 489, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -3.2591, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0008509008599997243, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.08749553670763105, \"functional effect\": -1.0383, \"times_seen\": 1.0}, {\"site\": 489, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"P\", \"log2 fold change IC90\": -0.015112146110694709, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": 0.086532757528968, \"functional effect\": -1.8611, \"times_seen\": 2.0}, {\"site\": 489, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -1.4113, \"times_seen\": null}, {\"site\": 489, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"492\", \"IC90\": null, \"functional effect\": -2.4571, \"times_seen\": null}, {\"site\": 490, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006437071255735139, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08705465551223623, \"functional effect\": -2.5897, \"times_seen\": 2.0}, {\"site\": 490, \"mutant\": \"A\", \"log2 fold change IC90\": 0.14723956666400861, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.09683966511866314, \"functional effect\": -0.3866, \"times_seen\": 45.0}, {\"site\": 490, \"mutant\": \"C\", \"log2 fold change IC90\": -0.027979035255106185, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.0857644336279254, \"functional effect\": -2.3533, \"times_seen\": 3.0}, {\"site\": 490, \"mutant\": \"D\", \"log2 fold change IC90\": 0.016657928342931887, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08845946102366946, \"functional effect\": -1.5278, \"times_seen\": 7.0}, {\"site\": 490, \"mutant\": \"E\", \"log2 fold change IC90\": 0.2105527799611222, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.10118414243448741, \"functional effect\": -0.2944, \"times_seen\": 16.0}, {\"site\": 490, \"mutant\": \"F\", \"log2 fold change IC90\": -0.029628147963989732, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08566645421542234, \"functional effect\": -2.0279, \"times_seen\": 2.0}, {\"site\": 490, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07546826495617494, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08298728210444475, \"functional effect\": -0.9766, \"times_seen\": 42.0}, {\"site\": 490, \"mutant\": \"H\", \"log2 fold change IC90\": -0.15969698517379882, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.07828096487973556, \"functional effect\": -0.7874, \"times_seen\": 46.0}, {\"site\": 490, \"mutant\": \"I\", \"log2 fold change IC90\": 0.023453617333080806, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08887712450048642, \"functional effect\": -1.119, \"times_seen\": 7.0}, {\"site\": 490, \"mutant\": \"K\", \"log2 fold change IC90\": 0.050284135378357304, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.09054548219378929, \"functional effect\": -0.0552, \"times_seen\": 34.0}, {\"site\": 490, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015608580657557497, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08650298653859406, \"functional effect\": -1.6339, \"times_seen\": 30.0}, {\"site\": 490, \"mutant\": \"M\", \"log2 fold change IC90\": 0.04238495366847125, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.09005107367132349, \"functional effect\": -0.8017, \"times_seen\": 6.0}, {\"site\": 490, \"mutant\": \"N\", \"log2 fold change IC90\": 0.011565062777771272, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08814774032913596, \"functional effect\": -0.746, \"times_seen\": 5.0}, {\"site\": 490, \"mutant\": \"P\", \"log2 fold change IC90\": -0.014039047645426031, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08659714585074692, \"functional effect\": -2.6584, \"times_seen\": 5.0}, {\"site\": 490, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.14862871671516292, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.0969329555291306, \"functional effect\": -0.2715, \"times_seen\": 26.0}, {\"site\": 490, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 490, \"mutant\": \"S\", \"log2 fold change IC90\": 0.021297826559526237, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08874441634081731, \"functional effect\": -0.6663, \"times_seen\": 45.0}, {\"site\": 490, \"mutant\": \"T\", \"log2 fold change IC90\": 0.007164090355581578, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08787925346166675, \"functional effect\": -0.8249, \"times_seen\": 22.0}, {\"site\": 490, \"mutant\": \"V\", \"log2 fold change IC90\": 1.041117437967038, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.17994398359981842, \"functional effect\": -0.7732, \"times_seen\": 34.0}, {\"site\": 490, \"mutant\": \"W\", \"log2 fold change IC90\": -0.06999554693961255, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.0833026838267186, \"functional effect\": -1.7173, \"times_seen\": 2.0}, {\"site\": 490, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.019110763625672645, \"epitope\": \"all\", \"reference_site\": \"493\", \"IC90\": 0.08629325276537357, \"functional effect\": -1.2071, \"times_seen\": 13.0}, {\"site\": 491, \"mutant\": \"A\", \"log2 fold change IC90\": 0.043725975074442994, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.09013481732907488, \"functional effect\": -0.1818, \"times_seen\": 3.0}, {\"site\": 491, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02943851213705359, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.08924658933204573, \"functional effect\": -1.5274, \"times_seen\": 2.0}, {\"site\": 491, \"mutant\": \"L\", \"log2 fold change IC90\": 4.398911103655658, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 1.8447348114409725, \"functional effect\": -1.0881, \"times_seen\": 11.0}, {\"site\": 491, \"mutant\": \"P\", \"log2 fold change IC90\": 0.04229855420338743, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.09004568089502211, \"functional effect\": -0.5503, \"times_seen\": 23.0}, {\"site\": 491, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 491, \"mutant\": \"T\", \"log2 fold change IC90\": 0.00407272688596376, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.0876911500480192, \"functional effect\": -0.1058, \"times_seen\": 11.0}, {\"site\": 491, \"mutant\": \"Y\", \"log2 fold change IC90\": 2.141137567883516, \"epitope\": \"all\", \"reference_site\": \"494\", \"IC90\": 0.38572375469471865, \"functional effect\": -0.9805, \"times_seen\": 5.0}, {\"site\": 492, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 492, \"mutant\": \"-\", \"log2 fold change IC90\": -0.009847653324494303, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.08684909829764885, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 492, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": null, \"functional effect\": -2.3157, \"times_seen\": null}, {\"site\": 492, \"mutant\": \"H\", \"log2 fold change IC90\": 0.010535155566380922, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.08808483611566394, \"functional effect\": -2.3786, \"times_seen\": 8.0}, {\"site\": 492, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": null, \"functional effect\": -2.2545, \"times_seen\": null}, {\"site\": 492, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0027096669391477586, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.08727986418814287, \"functional effect\": -2.1345, \"times_seen\": 1.0}, {\"site\": 492, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"495\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 493, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": null, \"functional effect\": -3.0079, \"times_seen\": null}, {\"site\": 493, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0027193681857052496, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08727927728612189, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 493, \"mutant\": \"A\", \"log2 fold change IC90\": -0.17096897499706087, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.07767172724939382, \"functional effect\": 0.0471, \"times_seen\": 44.0}, {\"site\": 493, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0481900108871893, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08457132095169627, \"functional effect\": -1.1981, \"times_seen\": 31.0}, {\"site\": 493, \"mutant\": \"D\", \"log2 fold change IC90\": -0.13563886042362816, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.07959730932250048, \"functional effect\": 0.2573, \"times_seen\": 29.0}, {\"site\": 493, \"mutant\": \"E\", \"log2 fold change IC90\": 0.12916371374852148, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.09563390839465875, \"functional effect\": 0.4075, \"times_seen\": 3.0}, {\"site\": 493, \"mutant\": \"F\", \"log2 fold change IC90\": 0.14559026450697893, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.09672902038546694, \"functional effect\": -0.6332, \"times_seen\": 19.0}, {\"site\": 493, \"mutant\": \"G\", \"log2 fold change IC90\": -0.615663104921267, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.05706853067045732, \"functional effect\": 0.0404, \"times_seen\": 50.0}, {\"site\": 493, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0932480443198244, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.09328250738943762, \"functional effect\": -0.0759, \"times_seen\": 23.0}, {\"site\": 493, \"mutant\": \"I\", \"log2 fold change IC90\": 0.024394971561105913, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08893513548411375, \"functional effect\": -0.1474, \"times_seen\": 33.0}, {\"site\": 493, \"mutant\": \"K\", \"log2 fold change IC90\": 3.3615579727727525, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.8987926966324803, \"functional effect\": -0.6137, \"times_seen\": 7.0}, {\"site\": 493, \"mutant\": \"L\", \"log2 fold change IC90\": 0.5152299119572565, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.12497680302590133, \"functional effect\": -0.5501, \"times_seen\": 34.0}, {\"site\": 493, \"mutant\": \"M\", \"log2 fold change IC90\": -0.926897131917111, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.045994501181792546, \"functional effect\": -0.1907, \"times_seen\": 7.0}, {\"site\": 493, \"mutant\": \"N\", \"log2 fold change IC90\": 2.0526814491487384, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.36278426363698263, \"functional effect\": 0.1379, \"times_seen\": 47.0}, {\"site\": 493, \"mutant\": \"P\", \"log2 fold change IC90\": 0.008376054446195534, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.087953109159126, \"functional effect\": -2.2628, \"times_seen\": 13.0}, {\"site\": 493, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01565344845956337, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.08650029633837092, \"functional effect\": 0.0007, \"times_seen\": 5.0}, {\"site\": 493, \"mutant\": \"R\", \"log2 fold change IC90\": 2.5198804299514146, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.5015212597587196, \"functional effect\": -1.4775, \"times_seen\": 39.0}, {\"site\": 493, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 493, \"mutant\": \"T\", \"log2 fold change IC90\": -1.3793978374554177, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.033611634152385175, \"functional effect\": 0.0331, \"times_seen\": 36.0}, {\"site\": 493, \"mutant\": \"V\", \"log2 fold change IC90\": -0.3110572392043082, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.07048426793987843, \"functional effect\": -0.1352, \"times_seen\": 46.0}, {\"site\": 493, \"mutant\": \"W\", \"log2 fold change IC90\": -0.03169966599989856, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.0855435368581673, \"functional effect\": -1.3651, \"times_seen\": 7.0}, {\"site\": 493, \"mutant\": \"Y\", \"log2 fold change IC90\": 2.0604514507223644, \"epitope\": \"all\", \"reference_site\": \"496\", \"IC90\": 0.3647434016668317, \"functional effect\": -0.4377, \"times_seen\": 12.0}, {\"site\": 494, \"mutant\": \"-\", \"log2 fold change IC90\": -0.009025553149604433, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.08689860217997877, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 494, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0010859244601317854, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.08737815232345063, \"functional effect\": -2.6818, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"L\", \"log2 fold change IC90\": -0.1337518933856757, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.0797014864096049, \"functional effect\": -2.4924, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005053702491348594, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.08713817035390072, \"functional effect\": -2.9094, \"times_seen\": 1.0}, {\"site\": 494, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": null, \"functional effect\": -3.006, \"times_seen\": null}, {\"site\": 494, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0485613094562652, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": 0.0904374198558676, \"functional effect\": -0.8619, \"times_seen\": 6.0}, {\"site\": 494, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"497\", \"IC90\": null, \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 495, \"mutant\": \"*\", \"log2 fold change IC90\": 0.035011078293335884, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08959198059454239, \"functional effect\": -2.4975, \"times_seen\": 2.0}, {\"site\": 495, \"mutant\": \"-\", \"log2 fold change IC90\": -0.003293993971161157, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.087244520850972, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 495, \"mutant\": \"A\", \"log2 fold change IC90\": -0.017154453917345346, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08641034669962512, \"functional effect\": -0.043, \"times_seen\": 5.0}, {\"site\": 495, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006272675959807692, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08706457596726778, \"functional effect\": -2.4122, \"times_seen\": 1.0}, {\"site\": 495, \"mutant\": \"D\", \"log2 fold change IC90\": 0.025259394862954504, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08898843894559551, \"functional effect\": -0.7782, \"times_seen\": 2.0}, {\"site\": 495, \"mutant\": \"E\", \"log2 fold change IC90\": 0.022826015999354046, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08883846957378845, \"functional effect\": -0.2172, \"times_seen\": 9.0}, {\"site\": 495, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0033112320223695393, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08764487641545272, \"functional effect\": -0.0421, \"times_seen\": 11.0}, {\"site\": 495, \"mutant\": \"G\", \"log2 fold change IC90\": -0.13122070827828478, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.07984144411885996, \"functional effect\": -0.3789, \"times_seen\": 28.0}, {\"site\": 495, \"mutant\": \"H\", \"log2 fold change IC90\": -0.041459701112852604, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08496677591922884, \"functional effect\": -0.2841, \"times_seen\": 10.0}, {\"site\": 495, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04153162190426075, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08496254028711114, \"functional effect\": -0.1404, \"times_seen\": 9.0}, {\"site\": 495, \"mutant\": \"K\", \"log2 fold change IC90\": -0.04493847823411739, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08476214196211507, \"functional effect\": 0.1592, \"times_seen\": 24.0}, {\"site\": 495, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009193897964003436, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08688846277063318, \"functional effect\": -0.3126, \"times_seen\": 16.0}, {\"site\": 495, \"mutant\": \"M\", \"log2 fold change IC90\": -0.09744511419762329, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08173270087634066, \"functional effect\": -0.1347, \"times_seen\": 15.0}, {\"site\": 495, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0077715041197355715, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08791626080224693, \"functional effect\": -0.0844, \"times_seen\": 5.0}, {\"site\": 495, \"mutant\": \"P\", \"log2 fold change IC90\": -0.002030710294599828, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08732094923275305, \"functional effect\": -2.7657, \"times_seen\": 1.0}, {\"site\": 495, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.023872652890446332, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08890294290527702, \"functional effect\": 0.0442, \"times_seen\": 8.0}, {\"site\": 495, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 495, \"mutant\": \"S\", \"log2 fold change IC90\": -0.09124430845410547, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.082084749853016, \"functional effect\": 0.0007, \"times_seen\": 13.0}, {\"site\": 495, \"mutant\": \"T\", \"log2 fold change IC90\": -0.049678286166542455, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08448412268450867, \"functional effect\": -0.1952, \"times_seen\": 12.0}, {\"site\": 495, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04509882419569784, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08475272173711128, \"functional effect\": -0.2869, \"times_seen\": 12.0}, {\"site\": 495, \"mutant\": \"W\", \"log2 fold change IC90\": 7.235225277890896, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 13.174968540132662, \"functional effect\": -0.8692, \"times_seen\": 9.0}, {\"site\": 495, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01635048039622209, \"epitope\": \"all\", \"reference_site\": \"498\", \"IC90\": 0.08645851418452033, \"functional effect\": -0.0976, \"times_seen\": 7.0}, {\"site\": 496, \"mutant\": \"-\", \"log2 fold change IC90\": 0.26315765557919135, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 0.10494170132455545, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 496, \"mutant\": \"H\", \"log2 fold change IC90\": 6.602149639536476, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 8.495223911174095, \"functional effect\": -0.4608, \"times_seen\": 4.0}, {\"site\": 496, \"mutant\": \"L\", \"log2 fold change IC90\": 0.49165599937875354, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 0.12295125220140185, \"functional effect\": -1.8239, \"times_seen\": 3.0}, {\"site\": 496, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 496, \"mutant\": \"Q\", \"log2 fold change IC90\": 6.452156675149968, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 7.656361817736739, \"functional effect\": -0.5042, \"times_seen\": 2.0}, {\"site\": 496, \"mutant\": \"R\", \"log2 fold change IC90\": 3.560340933968468, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 1.0315711049586611, \"functional effect\": -2.0994, \"times_seen\": 6.0}, {\"site\": 496, \"mutant\": \"S\", \"log2 fold change IC90\": 8.94213972725767, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 43.01124721427073, \"functional effect\": -0.0307, \"times_seen\": 10.0}, {\"site\": 496, \"mutant\": \"T\", \"log2 fold change IC90\": 8.673676088979718, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 35.708074177809614, \"functional effect\": -0.3631, \"times_seen\": 3.0}, {\"site\": 496, \"mutant\": \"V\", \"log2 fold change IC90\": 7.642355698947038, \"epitope\": \"all\", \"reference_site\": \"499\", \"IC90\": 17.470609467446057, \"functional effect\": -2.3457, \"times_seen\": 2.0}, {\"site\": 497, \"mutant\": \"-\", \"log2 fold change IC90\": 0.09276530077259869, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.09325129913403842, \"functional effect\": -0.3492, \"times_seen\": 1.0}, {\"site\": 497, \"mutant\": \"A\", \"log2 fold change IC90\": 5.620604569513587, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 4.302296349380756, \"functional effect\": -0.5078, \"times_seen\": 13.0}, {\"site\": 497, \"mutant\": \"I\", \"log2 fold change IC90\": 0.044563688235417995, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.09018717007637668, \"functional effect\": -1.0395, \"times_seen\": 5.0}, {\"site\": 497, \"mutant\": \"N\", \"log2 fold change IC90\": 1.9087348413508085, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.32833425420775625, \"functional effect\": 0.2023, \"times_seen\": 4.0}, {\"site\": 497, \"mutant\": \"S\", \"log2 fold change IC90\": 3.7679282767645637, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 1.1912123452992707, \"functional effect\": 0.006, \"times_seen\": 13.0}, {\"site\": 497, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"500\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 498, \"mutant\": \"*\", \"log2 fold change IC90\": 0.023765255250143596, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.0888963250056963, \"functional effect\": -2.8664, \"times_seen\": 3.0}, {\"site\": 498, \"mutant\": \"A\", \"log2 fold change IC90\": 0.07537414890701834, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.09213393764259087, \"functional effect\": 0.1028, \"times_seen\": 31.0}, {\"site\": 498, \"mutant\": \"C\", \"log2 fold change IC90\": -0.008395321773490713, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08693657152758703, \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 498, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03715843415543217, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08522047480747118, \"functional effect\": 0.1304, \"times_seen\": 9.0}, {\"site\": 498, \"mutant\": \"E\", \"log2 fold change IC90\": -0.20837939049865736, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.07568351706151404, \"functional effect\": 0.0618, \"times_seen\": 26.0}, {\"site\": 498, \"mutant\": \"F\", \"log2 fold change IC90\": -0.05555915721288182, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.0841404402330833, \"functional effect\": -0.0232, \"times_seen\": 28.0}, {\"site\": 498, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0896465899245067, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.0821757053005008, \"functional effect\": 0.0356, \"times_seen\": 17.0}, {\"site\": 498, \"mutant\": \"H\", \"log2 fold change IC90\": -0.07257147075424819, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08315408006218626, \"functional effect\": 0.0028, \"times_seen\": 26.0}, {\"site\": 498, \"mutant\": \"I\", \"log2 fold change IC90\": 1.95245411964782, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.3384363542170788, \"functional effect\": -0.3911, \"times_seen\": 48.0}, {\"site\": 498, \"mutant\": \"K\", \"log2 fold change IC90\": 0.017072356947767486, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08848487554023503, \"functional effect\": -2.849, \"times_seen\": 3.0}, {\"site\": 498, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0569842369949639, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.09096696755197754, \"functional effect\": 0.1459, \"times_seen\": 48.0}, {\"site\": 498, \"mutant\": \"M\", \"log2 fold change IC90\": 0.01591371367425804, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.08841384095179798, \"functional effect\": 0.1332, \"times_seen\": 14.0}, {\"site\": 498, \"mutant\": \"N\", \"log2 fold change IC90\": -0.4390866937695652, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.06449877811489105, \"functional effect\": 0.0985, \"times_seen\": 64.0}, {\"site\": 498, \"mutant\": \"P\", \"log2 fold change IC90\": 0.013391461215635168, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.0882594027659002, \"functional effect\": -2.004, \"times_seen\": 8.0}, {\"site\": 498, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.3446725655460159, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.06886094397652853, \"functional effect\": -0.1512, \"times_seen\": 11.0}, {\"site\": 498, \"mutant\": \"R\", \"log2 fold change IC90\": -0.02009810886936418, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.0862342159751336, \"functional effect\": -2.9894, \"times_seen\": 7.0}, {\"site\": 498, \"mutant\": \"S\", \"log2 fold change IC90\": -0.21358274466866964, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.07541104171919873, \"functional effect\": 0.0133, \"times_seen\": 73.0}, {\"site\": 498, \"mutant\": \"T\", \"log2 fold change IC90\": -0.4155746996619565, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.06555854446723233, \"functional effect\": -0.047, \"times_seen\": 50.0}, {\"site\": 498, \"mutant\": \"V\", \"log2 fold change IC90\": 0.05384714181916043, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.09076937763486008, \"functional effect\": -0.0001, \"times_seen\": 47.0}, {\"site\": 498, \"mutant\": \"W\", \"log2 fold change IC90\": 2.611214062299839, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.534297953438704, \"functional effect\": -0.376, \"times_seen\": 27.0}, {\"site\": 498, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"501\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 499, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0007756844262148728, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.0873969443169641, \"functional effect\": -3.0563, \"times_seen\": 1.0}, {\"site\": 499, \"mutant\": \"E\", \"log2 fold change IC90\": -0.015923299331825652, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.08648411828489642, \"functional effect\": -2.6212, \"times_seen\": 1.0}, {\"site\": 499, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 499, \"mutant\": \"R\", \"log2 fold change IC90\": 0.056298073282655646, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.09092371281740559, \"functional effect\": -2.936, \"times_seen\": 2.0}, {\"site\": 499, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04237241207393662, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.08491303928056514, \"functional effect\": -0.1043, \"times_seen\": 7.0}, {\"site\": 499, \"mutant\": \"V\", \"log2 fold change IC90\": 0.02653625847254313, \"epitope\": \"all\", \"reference_site\": \"502\", \"IC90\": 0.08906723341956244, \"functional effect\": -2.1212, \"times_seen\": 1.0}, {\"site\": 500, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0032425122265714755, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08724763417717833, \"functional effect\": 0.0538, \"times_seen\": 10.0}, {\"site\": 500, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005253762561986892, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08712608764801984, \"functional effect\": 0.3375, \"times_seen\": 1.0}, {\"site\": 500, \"mutant\": \"F\", \"log2 fold change IC90\": -0.05370672273327434, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08424854676766254, \"functional effect\": -0.1554, \"times_seen\": 12.0}, {\"site\": 500, \"mutant\": \"G\", \"log2 fold change IC90\": -0.010919179030073617, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08678461724803807, \"functional effect\": -0.7935, \"times_seen\": 8.0}, {\"site\": 500, \"mutant\": \"I\", \"log2 fold change IC90\": 0.010107967715782065, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08805875769972836, \"functional effect\": 0.1889, \"times_seen\": 10.0}, {\"site\": 500, \"mutant\": \"L\", \"log2 fold change IC90\": 0.007044482337567667, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08787196804976033, \"functional effect\": -0.1482, \"times_seen\": 16.0}, {\"site\": 500, \"mutant\": \"M\", \"log2 fold change IC90\": -0.024519759054631596, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.08597032526224653, \"functional effect\": -0.1088, \"times_seen\": 8.0}, {\"site\": 500, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"503\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 501, \"mutant\": \"C\", \"log2 fold change IC90\": 0.035403506961619265, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.08961635389784742, \"functional effect\": -2.5791, \"times_seen\": 1.0}, {\"site\": 501, \"mutant\": \"D\", \"log2 fold change IC90\": -0.48534681892073284, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.06246342618057274, \"functional effect\": -0.2888, \"times_seen\": 82.0}, {\"site\": 501, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 501, \"mutant\": \"N\", \"log2 fold change IC90\": 2.0754773184546065, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.3685621061237602, \"functional effect\": -0.2675, \"times_seen\": 5.0}, {\"site\": 501, \"mutant\": \"R\", \"log2 fold change IC90\": 0.062272578173405535, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.09130102784849906, \"functional effect\": -0.7602, \"times_seen\": 2.0}, {\"site\": 501, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05017684274524224, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.08445493228943858, \"functional effect\": -0.1053, \"times_seen\": 34.0}, {\"site\": 501, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0034175359283625927, \"epitope\": \"all\", \"reference_site\": \"504\", \"IC90\": 0.08765133470061032, \"functional effect\": -0.6904, \"times_seen\": 12.0}, {\"site\": 502, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": null, \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 502, \"mutant\": \"A\", \"log2 fold change IC90\": 0.8436183443144774, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.15692212454857368, \"functional effect\": -0.0962, \"times_seen\": 17.0}, {\"site\": 502, \"mutant\": \"C\", \"log2 fold change IC90\": -0.00811622964312968, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08695339120139875, \"functional effect\": -2.6374, \"times_seen\": 3.0}, {\"site\": 502, \"mutant\": \"D\", \"log2 fold change IC90\": -0.2651396398755116, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.07276369892069157, \"functional effect\": 0.2021, \"times_seen\": 20.0}, {\"site\": 502, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0060000128812530504, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.0870810323479279, \"functional effect\": 0.1255, \"times_seen\": 4.0}, {\"site\": 502, \"mutant\": \"F\", \"log2 fold change IC90\": -4.20939281616546, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.004726898225332085, \"functional effect\": -0.1583, \"times_seen\": 17.0}, {\"site\": 502, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0947126433993561, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08188764966438387, \"functional effect\": -0.7695, \"times_seen\": 9.0}, {\"site\": 502, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 502, \"mutant\": \"I\", \"log2 fold change IC90\": -0.008181501952196009, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.0869494572305502, \"functional effect\": -1.8906, \"times_seen\": 1.0}, {\"site\": 502, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03570928951540316, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.0853061192687074, \"functional effect\": -0.9618, \"times_seen\": 6.0}, {\"site\": 502, \"mutant\": \"L\", \"log2 fold change IC90\": -0.11877690350471601, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08053308612073173, \"functional effect\": -0.0845, \"times_seen\": 39.0}, {\"site\": 502, \"mutant\": \"M\", \"log2 fold change IC90\": -0.04660886989141199, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08466405883550045, \"functional effect\": 0.2724, \"times_seen\": 6.0}, {\"site\": 502, \"mutant\": \"N\", \"log2 fold change IC90\": -0.07597930718572313, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08295789093447388, \"functional effect\": -0.1694, \"times_seen\": 24.0}, {\"site\": 502, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0031428150772934847, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08725366361563736, \"functional effect\": -2.9748, \"times_seen\": 11.0}, {\"site\": 502, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08516780161608106, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08243121284973924, \"functional effect\": -0.0357, \"times_seen\": 27.0}, {\"site\": 502, \"mutant\": \"R\", \"log2 fold change IC90\": -0.2380500403191427, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.07414289681559122, \"functional effect\": -1.0928, \"times_seen\": 58.0}, {\"site\": 502, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06788320026912674, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08342474221410356, \"functional effect\": -0.3556, \"times_seen\": 23.0}, {\"site\": 502, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06461953557098367, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08361367929074104, \"functional effect\": -1.0339, \"times_seen\": 10.0}, {\"site\": 502, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0310157651856586, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08558409786490034, \"functional effect\": -1.2803, \"times_seen\": 6.0}, {\"site\": 502, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004484572239839556, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.08717255236165758, \"functional effect\": -0.1674, \"times_seen\": 7.0}, {\"site\": 502, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.6153037960238115, \"epitope\": \"all\", \"reference_site\": \"505\", \"IC90\": 0.0570827455834637, \"functional effect\": -0.1237, \"times_seen\": 40.0}, {\"site\": 503, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0004982577873889181, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": 0.0874137521462096, \"functional effect\": -3.1158, \"times_seen\": 1.0}, {\"site\": 503, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": null, \"functional effect\": -2.1871, \"times_seen\": null}, {\"site\": 503, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": null, \"functional effect\": -2.8228, \"times_seen\": null}, {\"site\": 503, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 503, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0016730530054441218, \"epitope\": \"all\", \"reference_site\": \"506\", \"IC90\": 0.08734259957786808, \"functional effect\": -2.8214, \"times_seen\": 1.0}, {\"site\": 504, \"mutant\": \"A\", \"log2 fold change IC90\": -0.008868498668179155, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.08690806263933118, \"functional effect\": -1.0223, \"times_seen\": 3.0}, {\"site\": 504, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0033860517584013306, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.08723895399098315, \"functional effect\": -2.8046, \"times_seen\": 1.0}, {\"site\": 504, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 504, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": null, \"functional effect\": -2.8992, \"times_seen\": null}, {\"site\": 504, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03888958935007019, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.08983316184211876, \"functional effect\": -2.3546, \"times_seen\": 2.0}, {\"site\": 504, \"mutant\": \"T\", \"log2 fold change IC90\": -0.002533371432281992, \"epitope\": \"all\", \"reference_site\": \"507\", \"IC90\": 0.08729053032869044, \"functional effect\": -1.6578, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"*\", \"log2 fold change IC90\": -0.008813904204957798, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08691135147631371, \"functional effect\": -1.0566, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 505, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03901524550402156, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08511086289772961, \"functional effect\": -0.9961, \"times_seen\": 5.0}, {\"site\": 505, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": null, \"functional effect\": -2.3822, \"times_seen\": null}, {\"site\": 505, \"mutant\": \"F\", \"log2 fold change IC90\": -0.004983142706994335, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08714243223925594, \"functional effect\": 0.0169, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"H\", \"log2 fold change IC90\": 0.010068541261289608, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08805635123331287, \"functional effect\": 0.1304, \"times_seen\": 11.0}, {\"site\": 505, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00469536399039209, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.08715981653595949, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 505, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"508\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 506, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 506, \"mutant\": \"G\", \"log2 fold change IC90\": -0.012843474111592802, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.08666893937886097, \"functional effect\": -2.951, \"times_seen\": 1.0}, {\"site\": 506, \"mutant\": \"K\", \"log2 fold change IC90\": 0.04537446542361439, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.09023786842127884, \"functional effect\": -1.815, \"times_seen\": 2.0}, {\"site\": 506, \"mutant\": \"M\", \"log2 fold change IC90\": -0.000927786770770727, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.0873877306030226, \"functional effect\": -2.8316, \"times_seen\": 1.0}, {\"site\": 506, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 506, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004295821458025845, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": 0.08718395807342592, \"functional effect\": -2.9775, \"times_seen\": 1.0}, {\"site\": 506, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"509\", \"IC90\": null, \"functional effect\": -3.2089, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": null, \"functional effect\": -2.4638, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": null, \"functional effect\": -2.8298, \"times_seen\": null}, {\"site\": 507, \"mutant\": \"I\", \"log2 fold change IC90\": -0.025516847905798605, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.08591092917684846, \"functional effect\": -0.8584, \"times_seen\": 4.0}, {\"site\": 507, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07829144169286649, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.08282504499200408, \"functional effect\": -2.6987, \"times_seen\": 5.0}, {\"site\": 507, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0061019503690025656, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.08707487962138752, \"functional effect\": -1.5842, \"times_seen\": 1.0}, {\"site\": 507, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"510\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 508, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 508, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": null, \"functional effect\": -3.0986, \"times_seen\": null}, {\"site\": 508, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02637872790937768, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.08905750853312061, \"functional effect\": -1.2286, \"times_seen\": 3.0}, {\"site\": 508, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03117654549547726, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.08935417064075336, \"functional effect\": -1.83, \"times_seen\": 2.0}, {\"site\": 508, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0035795987179570543, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.08722725110072116, \"functional effect\": -1.3902, \"times_seen\": 7.0}, {\"site\": 508, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"511\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.7182, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.9858, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011268862651604629, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": 0.08676358474921902, \"functional effect\": -1.3994, \"times_seen\": 4.0}, {\"site\": 509, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0046152663405196635, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": 0.08716465573625648, \"functional effect\": -2.8254, \"times_seen\": 1.0}, {\"site\": 509, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": null, \"functional effect\": -2.8415, \"times_seen\": null}, {\"site\": 509, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"512\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"F\", \"log2 fold change IC90\": -0.042665331950655486, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08489580057700817, \"functional effect\": -0.3652, \"times_seen\": 11.0}, {\"site\": 510, \"mutant\": \"I\", \"log2 fold change IC90\": -0.009332712890409949, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.0868801028366401, \"functional effect\": -1.4701, \"times_seen\": 2.0}, {\"site\": 510, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"M\", \"log2 fold change IC90\": -0.026351137726754074, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08586126248258205, \"functional effect\": -0.38, \"times_seen\": 9.0}, {\"site\": 510, \"mutant\": \"P\", \"log2 fold change IC90\": -0.016354975047991396, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08645824482731218, \"functional effect\": -2.8942, \"times_seen\": 5.0}, {\"site\": 510, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": null, \"functional effect\": -2.8948, \"times_seen\": null}, {\"site\": 510, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0052037814705486315, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.0871291061184954, \"functional effect\": -0.8287, \"times_seen\": 1.0}, {\"site\": 510, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00500198979503531, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08714129383486822, \"functional effect\": -2.4129, \"times_seen\": 1.0}, {\"site\": 510, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03560606459932079, \"epitope\": \"all\", \"reference_site\": \"513\", \"IC90\": 0.08531222314498448, \"functional effect\": -1.5414, \"times_seen\": 4.0}, {\"site\": 511, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": null, \"functional effect\": -2.1671, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": null, \"functional effect\": -3.1416, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005834988118365749, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08709099380772084, \"functional effect\": -0.8028, \"times_seen\": 1.0}, {\"site\": 511, \"mutant\": \"F\", \"log2 fold change IC90\": -0.060293070663553036, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.0838648027824937, \"functional effect\": -1.7083, \"times_seen\": 15.0}, {\"site\": 511, \"mutant\": \"N\", \"log2 fold change IC90\": 0.02209432208852607, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08879342465129837, \"functional effect\": 0.0622, \"times_seen\": 10.0}, {\"site\": 511, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": null, \"functional effect\": -2.608, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 511, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0344712788091861, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08537935388316222, \"functional effect\": -0.1658, \"times_seen\": 24.0}, {\"site\": 511, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05186269350572628, \"epitope\": \"all\", \"reference_site\": \"514\", \"IC90\": 0.08435630073352403, \"functional effect\": -1.2422, \"times_seen\": 23.0}, {\"site\": 512, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -2.9644, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -3.2839, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0065236186304433825, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": 0.08704943325410922, \"functional effect\": -0.3377, \"times_seen\": 12.0}, {\"site\": 512, \"mutant\": \"S\", \"log2 fold change IC90\": 0.011247011606412522, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": 0.08812830974873134, \"functional effect\": -2.6288, \"times_seen\": 5.0}, {\"site\": 512, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -2.6904, \"times_seen\": null}, {\"site\": 512, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"515\", \"IC90\": null, \"functional effect\": -2.3583, \"times_seen\": null}, {\"site\": 513, \"mutant\": \"*\", \"log2 fold change IC90\": 0.023914311866760442, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08890551008611605, \"functional effect\": -1.7671, \"times_seen\": 1.0}, {\"site\": 513, \"mutant\": \"A\", \"log2 fold change IC90\": 3.817644451557691e-05, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08744626105943643, \"functional effect\": -0.8865, \"times_seen\": 1.0}, {\"site\": 513, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 513, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03579044849873279, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08530132049766993, \"functional effect\": -0.6653, \"times_seen\": 5.0}, {\"site\": 513, \"mutant\": \"K\", \"log2 fold change IC90\": -0.013658357859665828, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08661999960560925, \"functional effect\": -1.2325, \"times_seen\": 26.0}, {\"site\": 513, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010036179139941238, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08805437600065326, \"functional effect\": -0.1296, \"times_seen\": 20.0}, {\"site\": 513, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0031491872983914746, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": 0.08725327822690826, \"functional effect\": -0.5221, \"times_seen\": 3.0}, {\"site\": 513, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"516\", \"IC90\": null, \"functional effect\": -0.8143, \"times_seen\": null}, {\"site\": 514, \"mutant\": \"F\", \"log2 fold change IC90\": -0.02766976708324746, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08578282077976664, \"functional effect\": 0.1757, \"times_seen\": 29.0}, {\"site\": 514, \"mutant\": \"H\", \"log2 fold change IC90\": -0.012361401763421804, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08669790439167557, \"functional effect\": -0.6957, \"times_seen\": 12.0}, {\"site\": 514, \"mutant\": \"I\", \"log2 fold change IC90\": 0.10615453019460241, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.09412076547389754, \"functional effect\": 0.1283, \"times_seen\": 32.0}, {\"site\": 514, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 514, \"mutant\": \"M\", \"log2 fold change IC90\": -0.007316585888371755, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08700160028753597, \"functional effect\": -0.1504, \"times_seen\": 3.0}, {\"site\": 514, \"mutant\": \"P\", \"log2 fold change IC90\": 2.3762239650383017, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.45398807229586186, \"functional effect\": -1.4089, \"times_seen\": 2.0}, {\"site\": 514, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0262649059132984, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08905048258290889, \"functional effect\": -1.2135, \"times_seen\": 2.0}, {\"site\": 514, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004254643281995621, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08718644656025525, \"functional effect\": -2.1178, \"times_seen\": 5.0}, {\"site\": 514, \"mutant\": \"T\", \"log2 fold change IC90\": -0.029489429917542862, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08567469161429511, \"functional effect\": -0.8606, \"times_seen\": 8.0}, {\"site\": 514, \"mutant\": \"V\", \"log2 fold change IC90\": -0.06887372114751104, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08336748438357636, \"functional effect\": -0.0136, \"times_seen\": 66.0}, {\"site\": 514, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012886800690641536, \"epitope\": \"all\", \"reference_site\": \"517\", \"IC90\": 0.08666633660269438, \"functional effect\": -0.9741, \"times_seen\": 7.0}, {\"site\": 515, \"mutant\": \"F\", \"log2 fold change IC90\": -0.084279492565284, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.0824819837598637, \"functional effect\": 0.19, \"times_seen\": 20.0}, {\"site\": 515, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": null, \"functional effect\": -0.5171, \"times_seen\": null}, {\"site\": 515, \"mutant\": \"I\", \"log2 fold change IC90\": -0.029819750547639592, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08565507771270565, \"functional effect\": 0.1959, \"times_seen\": 22.0}, {\"site\": 515, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 515, \"mutant\": \"M\", \"log2 fold change IC90\": -0.010439875114722611, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08681345433151098, \"functional effect\": -0.124, \"times_seen\": 7.0}, {\"site\": 515, \"mutant\": \"P\", \"log2 fold change IC90\": -0.04034773217052776, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08503228999767508, \"functional effect\": -0.3749, \"times_seen\": 14.0}, {\"site\": 515, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01248492603294004, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.08669048159160299, \"functional effect\": -0.5652, \"times_seen\": 10.0}, {\"site\": 515, \"mutant\": \"V\", \"log2 fold change IC90\": 0.007572861095979459, \"epitope\": \"all\", \"reference_site\": \"518\", \"IC90\": 0.0879041565465674, \"functional effect\": 0.0737, \"times_seen\": 5.0}, {\"site\": 516, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": null, \"functional effect\": -1.0538, \"times_seen\": null}, {\"site\": 516, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 516, \"mutant\": \"L\", \"log2 fold change IC90\": -0.067930669263915, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08342199733497634, \"functional effect\": -0.6861, \"times_seen\": 35.0}, {\"site\": 516, \"mutant\": \"N\", \"log2 fold change IC90\": 0.06338948504803534, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.09137173872391599, \"functional effect\": -0.7408, \"times_seen\": 21.0}, {\"site\": 516, \"mutant\": \"P\", \"log2 fold change IC90\": -0.04752420121776873, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08461035997028817, \"functional effect\": -0.1239, \"times_seen\": 21.0}, {\"site\": 516, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08288071094089498, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.0825619939001008, \"functional effect\": -0.0534, \"times_seen\": 14.0}, {\"site\": 516, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03142290844809924, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08555994856689411, \"functional effect\": -1.268, \"times_seen\": 9.0}, {\"site\": 516, \"mutant\": \"V\", \"log2 fold change IC90\": 0.024243256952326948, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08892578350779434, \"functional effect\": -0.6903, \"times_seen\": 1.0}, {\"site\": 516, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.023554384870161663, \"epitope\": \"all\", \"reference_site\": \"519\", \"IC90\": 0.08602787124659647, \"functional effect\": 0.0498, \"times_seen\": 34.0}, {\"site\": 517, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 517, \"mutant\": \"D\", \"log2 fold change IC90\": 0.00667085962485543, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08784921430672893, \"functional effect\": -0.6494, \"times_seen\": 4.0}, {\"site\": 517, \"mutant\": \"E\", \"log2 fold change IC90\": 0.010789044413572674, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08810033885518351, \"functional effect\": -0.226, \"times_seen\": 9.0}, {\"site\": 517, \"mutant\": \"G\", \"log2 fold change IC90\": -0.9163132373810889, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.04633316662684815, \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 517, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": null, \"functional effect\": -2.0683, \"times_seen\": null}, {\"site\": 517, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03176674070216523, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08553955980569111, \"functional effect\": -1.6363, \"times_seen\": 9.0}, {\"site\": 517, \"mutant\": \"S\", \"log2 fold change IC90\": -0.09421251438175776, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.08191604200519444, \"functional effect\": -0.13, \"times_seen\": 60.0}, {\"site\": 517, \"mutant\": \"T\", \"log2 fold change IC90\": 0.39155766487813154, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.1147097557389207, \"functional effect\": -1.255, \"times_seen\": 30.0}, {\"site\": 517, \"mutant\": \"V\", \"log2 fold change IC90\": -0.009574162258621398, \"epitope\": \"all\", \"reference_site\": \"520\", \"IC90\": 0.0868655638037354, \"functional effect\": -1.6988, \"times_seen\": 20.0}, {\"site\": 518, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0026043436029607103, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08728623624999726, \"functional effect\": -1.0538, \"times_seen\": 1.0}, {\"site\": 518, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0004731583789784251, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08741527294754957, \"functional effect\": -0.0597, \"times_seen\": 2.0}, {\"site\": 518, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03577675861601838, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08963954229093943, \"functional effect\": -1.6256, \"times_seen\": 13.0}, {\"site\": 518, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 518, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05425248089962707, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.09079488374952228, \"functional effect\": -0.2545, \"times_seen\": 18.0}, {\"site\": 518, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0651815433727502, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08358111358067861, \"functional effect\": -0.1971, \"times_seen\": 7.0}, {\"site\": 518, \"mutant\": \"S\", \"log2 fold change IC90\": 0.026855473190557082, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08908694286379752, \"functional effect\": -0.4019, \"times_seen\": 17.0}, {\"site\": 518, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06006790884396579, \"epitope\": \"all\", \"reference_site\": \"521\", \"IC90\": 0.08387789260722078, \"functional effect\": -0.3776, \"times_seen\": 22.0}, {\"site\": 519, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005052744750774175, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08713822820104558, \"functional effect\": -1.9549, \"times_seen\": 1.0}, {\"site\": 519, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": null, \"functional effect\": -0.36, \"times_seen\": null}, {\"site\": 519, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 519, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02783715183847996, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08577286863941955, \"functional effect\": -0.781, \"times_seen\": 25.0}, {\"site\": 519, \"mutant\": \"D\", \"log2 fold change IC90\": 0.17351559000719183, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.09861958034079789, \"functional effect\": -1.3558, \"times_seen\": 33.0}, {\"site\": 519, \"mutant\": \"E\", \"log2 fold change IC90\": -0.041074419894371106, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08498946988684766, \"functional effect\": -1.3925, \"times_seen\": 15.0}, {\"site\": 519, \"mutant\": \"F\", \"log2 fold change IC90\": -0.01864527753188171, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08632109980779668, \"functional effect\": -0.6136, \"times_seen\": 27.0}, {\"site\": 519, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0897025734921668, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.0930535439969292, \"functional effect\": -0.8527, \"times_seen\": 45.0}, {\"site\": 519, \"mutant\": \"H\", \"log2 fold change IC90\": -0.019911095812491536, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.0862453950318099, \"functional effect\": -1.3548, \"times_seen\": 5.0}, {\"site\": 519, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0007300376371141188, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08739970959506163, \"functional effect\": -1.092, \"times_seen\": 12.0}, {\"site\": 519, \"mutant\": \"K\", \"log2 fold change IC90\": -0.005468409696996611, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08711312581379745, \"functional effect\": -2.5438, \"times_seen\": 1.0}, {\"site\": 519, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04471666178724382, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.084775175265821, \"functional effect\": -1.747, \"times_seen\": 34.0}, {\"site\": 519, \"mutant\": \"M\", \"log2 fold change IC90\": 0.03847362446608846, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08980726443953499, \"functional effect\": -0.3471, \"times_seen\": 9.0}, {\"site\": 519, \"mutant\": \"N\", \"log2 fold change IC90\": -0.05057641861084236, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.0844315444778088, \"functional effect\": -1.8793, \"times_seen\": 6.0}, {\"site\": 519, \"mutant\": \"P\", \"log2 fold change IC90\": 0.07849703147072969, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.09233358835852812, \"functional effect\": 0.1483, \"times_seen\": 44.0}, {\"site\": 519, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013480383605749244, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08663068591164845, \"functional effect\": -1.8429, \"times_seen\": 3.0}, {\"site\": 519, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0473427769880684, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08462100070458783, \"functional effect\": -2.3261, \"times_seen\": 17.0}, {\"site\": 519, \"mutant\": \"S\", \"log2 fold change IC90\": -0.021075087607472506, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08617583878988984, \"functional effect\": -0.2522, \"times_seen\": 76.0}, {\"site\": 519, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07582309973642326, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08296687366592231, \"functional effect\": -1.2783, \"times_seen\": 67.0}, {\"site\": 519, \"mutant\": \"V\", \"log2 fold change IC90\": -0.7052569348464108, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.053632280102224254, \"functional effect\": -0.2323, \"times_seen\": 116.0}, {\"site\": 519, \"mutant\": \"W\", \"log2 fold change IC90\": -0.012610719485747062, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08668292308527724, \"functional effect\": -1.3283, \"times_seen\": 3.0}, {\"site\": 519, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.056999399068659036, \"epitope\": \"all\", \"reference_site\": \"522\", \"IC90\": 0.08405648478011753, \"functional effect\": 0.0691, \"times_seen\": 15.0}, {\"site\": 520, \"mutant\": \"A\", \"log2 fold change IC90\": -0.2315652542223328, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.07447691267629288, \"functional effect\": -0.4663, \"times_seen\": 46.0}, {\"site\": 520, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03160530301111527, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.08554913222487692, \"functional effect\": -1.99, \"times_seen\": 17.0}, {\"site\": 520, \"mutant\": \"K\", \"log2 fold change IC90\": -0.005269083364361738, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.08712516241126153, \"functional effect\": -2.2485, \"times_seen\": 1.0}, {\"site\": 520, \"mutant\": \"N\", \"log2 fold change IC90\": 0.20031577357200425, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.10046870612289506, \"functional effect\": -0.7974, \"times_seen\": 28.0}, {\"site\": 520, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005347732308450492, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.08712041288689307, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 520, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": null, \"functional effect\": -2.1929, \"times_seen\": null}, {\"site\": 520, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05994336659895257, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.0838851337716146, \"functional effect\": 0.2301, \"times_seen\": 14.0}, {\"site\": 520, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"523\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -3.2398, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"C\", \"log2 fold change IC90\": -0.004909524850660971, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": 0.08714687905757619, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 521, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005413991013683713, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": 0.0871164117965454, \"functional effect\": -2.1667, \"times_seen\": 1.0}, {\"site\": 521, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -0.1108, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -2.3718, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -0.9578, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -2.8275, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": null, \"functional effect\": -3.0875, \"times_seen\": null}, {\"site\": 521, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"524\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -2.9129, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -2.9482, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -1.8801, \"times_seen\": null}, {\"site\": 522, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004660366614805419, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": 0.08716193091339033, \"functional effect\": -0.9191, \"times_seen\": 1.0}, {\"site\": 522, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"525\", \"IC90\": null, \"functional effect\": -3.1198, \"times_seen\": null}, {\"site\": 523, \"mutant\": \"*\", \"log2 fold change IC90\": -0.004093513582492767, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.08719618466156624, \"functional effect\": -2.1818, \"times_seen\": 1.0}, {\"site\": 523, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004305781233356147, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.08718335619318587, \"functional effect\": -0.6305, \"times_seen\": 2.0}, {\"site\": 523, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0027127044762713043, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.08727968042404789, \"functional effect\": -1.0706, \"times_seen\": 2.0}, {\"site\": 523, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 523, \"mutant\": \"P\", \"log2 fold change IC90\": -0.012294257170859092, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.08670193950011376, \"functional effect\": -0.6872, \"times_seen\": 3.0}, {\"site\": 523, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": null, \"functional effect\": -2.4069, \"times_seen\": null}, {\"site\": 523, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004674773627461003, \"epitope\": \"all\", \"reference_site\": \"526\", \"IC90\": 0.08716106050298748, \"functional effect\": -2.7353, \"times_seen\": 1.0}, {\"site\": 524, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": null, \"functional effect\": -2.6649, \"times_seen\": null}, {\"site\": 524, \"mutant\": \"K\", \"log2 fold change IC90\": -0.017119498811141814, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.08641244036415736, \"functional effect\": -0.785, \"times_seen\": 2.0}, {\"site\": 524, \"mutant\": \"L\", \"log2 fold change IC90\": -1.1430934295702562, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.03959354087152143, \"functional effect\": -2.6974, \"times_seen\": 2.0}, {\"site\": 524, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 524, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": null, \"functional effect\": -2.5665, \"times_seen\": null}, {\"site\": 524, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03344009566976267, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.08544040158875194, \"functional effect\": -1.9063, \"times_seen\": 5.0}, {\"site\": 524, \"mutant\": \"T\", \"log2 fold change IC90\": 0.006268168720710034, \"epitope\": \"all\", \"reference_site\": \"527\", \"IC90\": 0.08782469689879661, \"functional effect\": -1.7467, \"times_seen\": 3.0}, {\"site\": 525, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0748533722898434, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08302265974536789, \"functional effect\": -0.5715, \"times_seen\": 16.0}, {\"site\": 525, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": null, \"functional effect\": -0.7343, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"I\", \"log2 fold change IC90\": -0.053537039005326414, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08425845631043641, \"functional effect\": 0.0142, \"times_seen\": 16.0}, {\"site\": 525, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005962566031414958, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08708329266807208, \"functional effect\": -2.2802, \"times_seen\": 1.0}, {\"site\": 525, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": null, \"functional effect\": -2.9407, \"times_seen\": null}, {\"site\": 525, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0440594796606087, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08481380118436631, \"functional effect\": -0.0454, \"times_seen\": 10.0}, {\"site\": 525, \"mutant\": \"R\", \"log2 fold change IC90\": -0.027164266957882377, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08581288314447294, \"functional effect\": -0.3537, \"times_seen\": 5.0}, {\"site\": 525, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011094797524858821, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08677405364601622, \"functional effect\": -0.0315, \"times_seen\": 2.0}, {\"site\": 525, \"mutant\": \"W\", \"log2 fold change IC90\": -0.01663540019556582, \"epitope\": \"all\", \"reference_site\": \"528\", \"IC90\": 0.08644144106130341, \"functional effect\": -0.7099, \"times_seen\": 4.0}, {\"site\": 526, \"mutant\": \"E\", \"log2 fold change IC90\": -0.050657389354167005, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08442680592054021, \"functional effect\": -0.2878, \"times_seen\": 11.0}, {\"site\": 526, \"mutant\": \"G\", \"log2 fold change IC90\": -0.00703428850340186, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08701862587271782, \"functional effect\": -0.6437, \"times_seen\": 2.0}, {\"site\": 526, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 526, \"mutant\": \"L\", \"log2 fold change IC90\": -0.007150219860541943, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08701163355501511, \"functional effect\": -0.2172, \"times_seen\": 5.0}, {\"site\": 526, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0418578482680717, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08494333048441383, \"functional effect\": -0.3064, \"times_seen\": 11.0}, {\"site\": 526, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0006723164107607395, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08740320646667965, \"functional effect\": -0.3323, \"times_seen\": 17.0}, {\"site\": 526, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.007080280852045761, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08787414850013936, \"functional effect\": -0.2839, \"times_seen\": 11.0}, {\"site\": 526, \"mutant\": \"R\", \"log2 fold change IC90\": 0.7787138798237963, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.15001890413732788, \"functional effect\": -0.3896, \"times_seen\": 37.0}, {\"site\": 526, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011479482017581605, \"epitope\": \"all\", \"reference_site\": \"529\", \"IC90\": 0.08675091903897708, \"functional effect\": -0.0142, \"times_seen\": 7.0}, {\"site\": 527, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": null, \"functional effect\": -3.261, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"G\", \"log2 fold change IC90\": -0.02133246352550006, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08616046644390048, \"functional effect\": -1.2372, \"times_seen\": 4.0}, {\"site\": 527, \"mutant\": \"I\", \"log2 fold change IC90\": -0.010260663556465481, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08682423896744107, \"functional effect\": -0.6498, \"times_seen\": 2.0}, {\"site\": 527, \"mutant\": \"N\", \"log2 fold change IC90\": -0.11883877688215096, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08052963234356945, \"functional effect\": -1.1321, \"times_seen\": 21.0}, {\"site\": 527, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": null, \"functional effect\": -2.6451, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 527, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01709616593622186, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.0864138379339209, \"functional effect\": -0.5927, \"times_seen\": 6.0}, {\"site\": 527, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0061996498264010255, \"epitope\": \"all\", \"reference_site\": \"530\", \"IC90\": 0.08706898310119145, \"functional effect\": -2.5076, \"times_seen\": 1.0}, {\"site\": 528, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -2.6907, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"G\", \"log2 fold change IC90\": 0.02285442209978793, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": 0.08884021878568815, \"functional effect\": -2.6095, \"times_seen\": 2.0}, {\"site\": 528, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -3.0131, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"L\", \"log2 fold change IC90\": 0.028945557984203375, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": 0.08921609989372599, \"functional effect\": -2.8056, \"times_seen\": 1.0}, {\"site\": 528, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -1.7137, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": null, \"functional effect\": -1.218, \"times_seen\": null}, {\"site\": 528, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"531\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 529, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": null, \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 529, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0007885563569062698, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08749175576450517, \"functional effect\": 0.1006, \"times_seen\": 10.0}, {\"site\": 529, \"mutant\": \"H\", \"log2 fold change IC90\": 0.014860246125871581, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08834930401799543, \"functional effect\": 0.1214, \"times_seen\": 3.0}, {\"site\": 529, \"mutant\": \"I\", \"log2 fold change IC90\": 0.016056901722464597, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08842261649564308, \"functional effect\": -1.0965, \"times_seen\": 6.0}, {\"site\": 529, \"mutant\": \"K\", \"log2 fold change IC90\": -0.011319980330616637, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08676051058983188, \"functional effect\": -0.0009, \"times_seen\": 11.0}, {\"site\": 529, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 529, \"mutant\": \"P\", \"log2 fold change IC90\": 0.07674456768697605, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.0922214974262763, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 529, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03923216904377162, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08509806659554282, \"functional effect\": -0.0208, \"times_seen\": 22.0}, {\"site\": 529, \"mutant\": \"V\", \"log2 fold change IC90\": -0.002389497892208822, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08729923585792188, \"functional effect\": -0.3049, \"times_seen\": 1.0}, {\"site\": 529, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.021191206655697778, \"epitope\": \"all\", \"reference_site\": \"532\", \"IC90\": 0.08616890298335993, \"functional effect\": -0.1035, \"times_seen\": 5.0}, {\"site\": 530, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -1.6207, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"F\", \"log2 fold change IC90\": -0.006486670922887634, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.08705166263599291, \"functional effect\": -2.0848, \"times_seen\": 2.0}, {\"site\": 530, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"M\", \"log2 fold change IC90\": 0.06442551992685658, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.09143737858826526, \"functional effect\": -1.0553, \"times_seen\": 6.0}, {\"site\": 530, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -2.1012, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -3.1267, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -3.2559, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": null, \"functional effect\": -2.5095, \"times_seen\": null}, {\"site\": 530, \"mutant\": \"V\", \"log2 fold change IC90\": 0.06181703883994032, \"epitope\": \"all\", \"reference_site\": \"533\", \"IC90\": 0.09127220356994373, \"functional effect\": -1.1578, \"times_seen\": 7.0}, {\"site\": 531, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": null, \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 531, \"mutant\": \"A\", \"log2 fold change IC90\": 0.039770688774623655, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.08988804254814402, \"functional effect\": -1.5204, \"times_seen\": 9.0}, {\"site\": 531, \"mutant\": \"F\", \"log2 fold change IC90\": -0.022594491183881023, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.0860851287304124, \"functional effect\": -2.7729, \"times_seen\": 6.0}, {\"site\": 531, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": null, \"functional effect\": -1.9197, \"times_seen\": null}, {\"site\": 531, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05599408953668863, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.084115078059881, \"functional effect\": -0.0695, \"times_seen\": 28.0}, {\"site\": 531, \"mutant\": \"L\", \"log2 fold change IC90\": -0.02490231901037236, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.08594753150284981, \"functional effect\": -0.7782, \"times_seen\": 8.0}, {\"site\": 531, \"mutant\": \"M\", \"log2 fold change IC90\": -0.016028366798728107, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.0864778201164633, \"functional effect\": -1.2792, \"times_seen\": 5.0}, {\"site\": 531, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": null, \"functional effect\": -2.5316, \"times_seen\": null}, {\"site\": 531, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"534\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": null, \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"E\", \"log2 fold change IC90\": -0.003964880486748269, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.08720395956540923, \"functional effect\": -1.3257, \"times_seen\": 1.0}, {\"site\": 532, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": null, \"functional effect\": -1.7736, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": null, \"functional effect\": -2.633, \"times_seen\": null}, {\"site\": 532, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03889371738904733, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.08511803267242012, \"functional effect\": -0.6013, \"times_seen\": 12.0}, {\"site\": 532, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07537712908307577, \"epitope\": \"all\", \"reference_site\": \"535\", \"IC90\": 0.09213412796392063, \"functional effect\": -0.4288, \"times_seen\": 6.0}, {\"site\": 533, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": null, \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 533, \"mutant\": \"D\", \"log2 fold change IC90\": -0.07394609906311919, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08307488694789575, \"functional effect\": -0.1753, \"times_seen\": 17.0}, {\"site\": 533, \"mutant\": \"K\", \"log2 fold change IC90\": -0.09552621915630435, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08184148396528539, \"functional effect\": -0.5918, \"times_seen\": 18.0}, {\"site\": 533, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 533, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": null, \"functional effect\": -3.0933, \"times_seen\": null}, {\"site\": 533, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014639618762637596, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08656110433146628, \"functional effect\": -1.124, \"times_seen\": 3.0}, {\"site\": 533, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05142058996164331, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08438215507787235, \"functional effect\": -0.7847, \"times_seen\": 8.0}, {\"site\": 533, \"mutant\": \"W\", \"log2 fold change IC90\": -0.003789416254146536, \"epitope\": \"all\", \"reference_site\": \"536\", \"IC90\": 0.08721456617729388, \"functional effect\": -0.9078, \"times_seen\": 1.0}, {\"site\": 534, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": null, \"functional effect\": -2.101, \"times_seen\": null}, {\"site\": 534, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": null, \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 534, \"mutant\": \"E\", \"log2 fold change IC90\": -0.02330641519460066, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08604265894331353, \"functional effect\": -0.9206, \"times_seen\": 5.0}, {\"site\": 534, \"mutant\": \"G\", \"log2 fold change IC90\": -0.031464046910650974, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08555750885894674, \"functional effect\": -2.6262, \"times_seen\": 1.0}, {\"site\": 534, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 534, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0135273622232784, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08662786499421087, \"functional effect\": -1.5978, \"times_seen\": 5.0}, {\"site\": 534, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0003412336279840777, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08746463223317097, \"functional effect\": -2.6023, \"times_seen\": 5.0}, {\"site\": 534, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0044673169201423476, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08717359499313038, \"functional effect\": -0.5799, \"times_seen\": 2.0}, {\"site\": 534, \"mutant\": \"R\", \"log2 fold change IC90\": -0.012751763267952338, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.0866744490215553, \"functional effect\": -0.2885, \"times_seen\": 3.0}, {\"site\": 534, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0037373413764686405, \"epitope\": \"all\", \"reference_site\": \"537\", \"IC90\": 0.08721771429224891, \"functional effect\": -0.2944, \"times_seen\": 3.0}, {\"site\": 535, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -2.9372, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -1.7191, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"F\", \"log2 fold change IC90\": -0.004635691609259461, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": 0.08716342169242552, \"functional effect\": -2.9432, \"times_seen\": 1.0}, {\"site\": 535, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -3.0562, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -2.9066, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -3.233, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": null, \"functional effect\": -2.4097, \"times_seen\": null}, {\"site\": 535, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004540941984713044, \"epitope\": \"all\", \"reference_site\": \"538\", \"IC90\": 0.08716914637605463, \"functional effect\": -2.6424, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"A\", \"log2 fold change IC90\": -0.005006011722448649, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.08714105090378435, \"functional effect\": -2.5994, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005690895768803496, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.08709969264723678, \"functional effect\": -2.9985, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": null, \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 536, \"mutant\": \"I\", \"log2 fold change IC90\": -0.029787693437409602, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.08565698101499564, \"functional effect\": -0.192, \"times_seen\": 11.0}, {\"site\": 536, \"mutant\": \"L\", \"log2 fold change IC90\": -0.004776988176502851, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.0871548853844464, \"functional effect\": -1.9369, \"times_seen\": 1.0}, {\"site\": 536, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": null, \"functional effect\": -2.809, \"times_seen\": null}, {\"site\": 536, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"539\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 537, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": null, \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 537, \"mutant\": \"D\", \"log2 fold change IC90\": 0.00013531148618476846, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08745214891648624, \"functional effect\": -0.2562, \"times_seen\": 16.0}, {\"site\": 537, \"mutant\": \"H\", \"log2 fold change IC90\": 0.003437860912233984, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08765256955930383, \"functional effect\": -0.395, \"times_seen\": 1.0}, {\"site\": 537, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0050903279601776435, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08713595821915203, \"functional effect\": -1.0693, \"times_seen\": 1.0}, {\"site\": 537, \"mutant\": \"K\", \"log2 fold change IC90\": -0.017634366714516483, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.0863816070607053, \"functional effect\": -0.1286, \"times_seen\": 11.0}, {\"site\": 537, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 537, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.034863647573367046, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08958282555141175, \"functional effect\": -0.6167, \"times_seen\": 7.0}, {\"site\": 537, \"mutant\": \"S\", \"log2 fold change IC90\": -0.15490924543900866, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.07854118027706648, \"functional effect\": -0.1715, \"times_seen\": 32.0}, {\"site\": 537, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0826002536979634, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.09259657152874823, \"functional effect\": -0.232, \"times_seen\": 10.0}, {\"site\": 537, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04013477007581954, \"epitope\": \"all\", \"reference_site\": \"540\", \"IC90\": 0.08504484288702063, \"functional effect\": -0.5861, \"times_seen\": 14.0}, {\"site\": 538, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -2.4815, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -2.7164, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -3.0898, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"L\", \"log2 fold change IC90\": 0.035732477368627016, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.08963679098888329, \"functional effect\": -3.1258, \"times_seen\": 1.0}, {\"site\": 538, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": null, \"functional effect\": -2.6257, \"times_seen\": null}, {\"site\": 538, \"mutant\": \"S\", \"log2 fold change IC90\": 1.81402775789736, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.307472671251722, \"functional effect\": -2.8348, \"times_seen\": 2.0}, {\"site\": 538, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.034740496349215576, \"epitope\": \"all\", \"reference_site\": \"541\", \"IC90\": 0.08957517891545339, \"functional effect\": 0.0416, \"times_seen\": 1.0}, {\"site\": 539, \"mutant\": \"D\", \"log2 fold change IC90\": 0.052027754750973126, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.09065498024751072, \"functional effect\": -0.5205, \"times_seen\": 10.0}, {\"site\": 539, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0006418049889224176, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.08740505496842607, \"functional effect\": -2.7926, \"times_seen\": 1.0}, {\"site\": 539, \"mutant\": \"K\", \"log2 fold change IC90\": 0.02772452871219053, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.08914062352450663, \"functional effect\": -2.9886, \"times_seen\": 1.0}, {\"site\": 539, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 539, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": null, \"functional effect\": -2.4756, \"times_seen\": null}, {\"site\": 539, \"mutant\": \"S\", \"log2 fold change IC90\": 0.1365619535229871, \"epitope\": \"all\", \"reference_site\": \"542\", \"IC90\": 0.09612558527857695, \"functional effect\": -2.3102, \"times_seen\": 2.0}, {\"site\": 540, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -0.0019, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0242376183347331, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.08598713969683797, \"functional effect\": -1.8554, \"times_seen\": 6.0}, {\"site\": 540, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -2.6852, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"T\", \"log2 fold change IC90\": -0.001440352230861228, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.08735668871606596, \"functional effect\": -2.9328, \"times_seen\": 1.0}, {\"site\": 540, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0014665488747152144, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": 0.08753288205569186, \"functional effect\": -0.5522, \"times_seen\": 1.0}, {\"site\": 540, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -2.935, \"times_seen\": null}, {\"site\": 540, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"543\", \"IC90\": null, \"functional effect\": -2.884, \"times_seen\": null}, {\"site\": 541, \"mutant\": \"D\", \"log2 fold change IC90\": 0.04174211676046358, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.09001095759889113, \"functional effect\": -0.7887, \"times_seen\": 1.0}, {\"site\": 541, \"mutant\": \"G\", \"log2 fold change IC90\": 0.022916006768180872, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08884401121030708, \"functional effect\": -0.1076, \"times_seen\": 2.0}, {\"site\": 541, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 541, \"mutant\": \"K\", \"log2 fold change IC90\": -0.019869446483513985, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08624788489597317, \"functional effect\": -2.0814, \"times_seen\": 2.0}, {\"site\": 541, \"mutant\": \"M\", \"log2 fold change IC90\": -0.024869755491166556, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.08594947147325206, \"functional effect\": 0.329, \"times_seen\": 8.0}, {\"site\": 541, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 541, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06761332889122754, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": 0.0834403491548372, \"functional effect\": 0.3651, \"times_seen\": 10.0}, {\"site\": 541, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"544\", \"IC90\": null, \"functional effect\": -0.4128, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"*\", \"log2 fold change IC90\": 0.01424588415993938, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.08831168907155774, \"functional effect\": -1.8548, \"times_seen\": 2.0}, {\"site\": 542, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": null, \"functional effect\": -2.9755, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": null, \"functional effect\": -2.7771, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 542, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005148907271539836, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.08713242021516984, \"functional effect\": -2.745, \"times_seen\": 1.0}, {\"site\": 542, \"mutant\": \"V\", \"log2 fold change IC90\": -0.003628870415106163, \"epitope\": \"all\", \"reference_site\": \"545\", \"IC90\": 0.08722427211958694, \"functional effect\": -2.9644, \"times_seen\": 1.0}, {\"site\": 543, \"mutant\": \"F\", \"log2 fold change IC90\": -0.021098846725148876, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08617441960913622, \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 543, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 543, \"mutant\": \"M\", \"log2 fold change IC90\": 0.028622948637999187, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.0891961519982711, \"functional effect\": 0.2297, \"times_seen\": 4.0}, {\"site\": 543, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": null, \"functional effect\": -2.9377, \"times_seen\": null}, {\"site\": 543, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.002135648056473195, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08731459797245902, \"functional effect\": -0.6673, \"times_seen\": 3.0}, {\"site\": 543, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0028808904123171944, \"epitope\": \"all\", \"reference_site\": \"546\", \"IC90\": 0.08726950616078832, \"functional effect\": -0.3809, \"times_seen\": 5.0}, {\"site\": 544, \"mutant\": \"*\", \"log2 fold change IC90\": -0.016572902277943273, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08644518580771765, \"functional effect\": -2.6006, \"times_seen\": 4.0}, {\"site\": 544, \"mutant\": \"A\", \"log2 fold change IC90\": -0.08641541408017221, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08235995887673096, \"functional effect\": -0.3784, \"times_seen\": 19.0}, {\"site\": 544, \"mutant\": \"C\", \"log2 fold change IC90\": -0.011602933194819504, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.0867434960947053, \"functional effect\": -0.4923, \"times_seen\": 2.0}, {\"site\": 544, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": null, \"functional effect\": -2.6726, \"times_seen\": null}, {\"site\": 544, \"mutant\": \"E\", \"log2 fold change IC90\": -0.042052490352411265, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08493187107604197, \"functional effect\": -1.4994, \"times_seen\": 26.0}, {\"site\": 544, \"mutant\": \"F\", \"log2 fold change IC90\": -0.017487674862113042, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08639039070647096, \"functional effect\": -0.7061, \"times_seen\": 4.0}, {\"site\": 544, \"mutant\": \"G\", \"log2 fold change IC90\": -0.053069829986792584, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08428574737648437, \"functional effect\": -0.9731, \"times_seen\": 10.0}, {\"site\": 544, \"mutant\": \"H\", \"log2 fold change IC90\": -0.18081928891256002, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.07714321297831869, \"functional effect\": -0.5209, \"times_seen\": 11.0}, {\"site\": 544, \"mutant\": \"I\", \"log2 fold change IC90\": -1.1925405655057442, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.03825949836797674, \"functional effect\": -0.2457, \"times_seen\": 27.0}, {\"site\": 544, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 544, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08630170169767118, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08236645069653793, \"functional effect\": -0.8051, \"times_seen\": 18.0}, {\"site\": 544, \"mutant\": \"M\", \"log2 fold change IC90\": -0.5850744595106235, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.058291440911051755, \"functional effect\": -0.3205, \"times_seen\": 18.0}, {\"site\": 544, \"mutant\": \"N\", \"log2 fold change IC90\": 0.9357394631516269, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.1672689764400619, \"functional effect\": -1.3329, \"times_seen\": 20.0}, {\"site\": 544, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0279368517646933, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08576694136237613, \"functional effect\": -2.1393, \"times_seen\": 6.0}, {\"site\": 544, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03634362114362432, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08526861967694373, \"functional effect\": -0.1241, \"times_seen\": 10.0}, {\"site\": 544, \"mutant\": \"R\", \"log2 fold change IC90\": -0.02541296709846653, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08591711538927667, \"functional effect\": 0.0268, \"times_seen\": 42.0}, {\"site\": 544, \"mutant\": \"S\", \"log2 fold change IC90\": -0.039151057869946077, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08510285111196055, \"functional effect\": -0.3465, \"times_seen\": 18.0}, {\"site\": 544, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07770207599550696, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.0828588873572319, \"functional effect\": -0.3819, \"times_seen\": 29.0}, {\"site\": 544, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05294569633293143, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08429299987796736, \"functional effect\": -0.4142, \"times_seen\": 13.0}, {\"site\": 544, \"mutant\": \"W\", \"log2 fold change IC90\": -0.01805076053864988, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.08635667900835443, \"functional effect\": -1.8383, \"times_seen\": 4.0}, {\"site\": 544, \"mutant\": \"Y\", \"log2 fold change IC90\": -1.3132744510699461, \"epitope\": \"all\", \"reference_site\": \"547\", \"IC90\": 0.03518801354822365, \"functional effect\": -1.3953, \"times_seen\": 5.0}, {\"site\": 545, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01921880866339477, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.08628679040959576, \"functional effect\": -2.5715, \"times_seen\": 4.0}, {\"site\": 545, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005700617472950649, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.08709910572167992, \"functional effect\": -2.5343, \"times_seen\": 1.0}, {\"site\": 545, \"mutant\": \"D\", \"log2 fold change IC90\": 0.016178426584168477, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.08843006505443254, \"functional effect\": -2.9045, \"times_seen\": 2.0}, {\"site\": 545, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -2.9917, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -2.9874, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -3.0095, \"times_seen\": null}, {\"site\": 545, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"548\", \"IC90\": null, \"functional effect\": -2.7874, \"times_seen\": null}, {\"site\": 546, \"mutant\": \"A\", \"log2 fold change IC90\": 0.7872411588755176, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.15090824048110707, \"functional effect\": -0.425, \"times_seen\": 31.0}, {\"site\": 546, \"mutant\": \"I\", \"log2 fold change IC90\": -0.08095217219724783, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08267243336869556, \"functional effect\": -0.1083, \"times_seen\": 43.0}, {\"site\": 546, \"mutant\": \"K\", \"log2 fold change IC90\": -0.016730341643784355, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08643575267579356, \"functional effect\": -0.3882, \"times_seen\": 9.0}, {\"site\": 546, \"mutant\": \"P\", \"log2 fold change IC90\": -0.011995355182805527, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08671990453510019, \"functional effect\": -2.7505, \"times_seen\": 2.0}, {\"site\": 546, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.028982096736502597, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08570482497996099, \"functional effect\": -0.6592, \"times_seen\": 10.0}, {\"site\": 546, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": null, \"functional effect\": -1.0964, \"times_seen\": null}, {\"site\": 546, \"mutant\": \"S\", \"log2 fold change IC90\": 0.011458311480994306, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.08814121813477696, \"functional effect\": -0.4187, \"times_seen\": 2.0}, {\"site\": 546, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"549\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 547, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0253399965483867, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.088993410764536, \"functional effect\": -2.8942, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"A\", \"log2 fold change IC90\": -0.003463072296927485, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08723429672685433, \"functional effect\": -0.8664, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004283803244199153, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08718468435291325, \"functional effect\": -1.8394, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 547, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": null, \"functional effect\": -2.7598, \"times_seen\": null}, {\"site\": 547, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0013983011510452104, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08735923498989519, \"functional effect\": -2.7216, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0007887012872426836, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": 0.08749176455375714, \"functional effect\": -2.4634, \"times_seen\": 1.0}, {\"site\": 547, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"550\", \"IC90\": null, \"functional effect\": -2.9819, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -2.9188, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -3.0603, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"F\", \"log2 fold change IC90\": -0.010558538814783941, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.0868063140962118, \"functional effect\": -1.1944, \"times_seen\": 3.0}, {\"site\": 548, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -2.8877, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"I\", \"log2 fold change IC90\": 0.025076974540096404, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08897718759098242, \"functional effect\": -0.3624, \"times_seen\": 8.0}, {\"site\": 548, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03933820119743068, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08986110017000755, \"functional effect\": -1.7071, \"times_seen\": 4.0}, {\"site\": 548, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": null, \"functional effect\": -0.1976, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01219596911296673, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08670784653888483, \"functional effect\": -0.4589, \"times_seen\": 10.0}, {\"site\": 548, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 548, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0031642094400093335, \"epitope\": \"all\", \"reference_site\": \"551\", \"IC90\": 0.08763594513120022, \"functional effect\": -2.2832, \"times_seen\": 3.0}, {\"site\": 549, \"mutant\": \"F\", \"log2 fold change IC90\": -0.008512612018420093, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.08692950392355937, \"functional effect\": -2.7077, \"times_seen\": 1.0}, {\"site\": 549, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -2.9185, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"I\", \"log2 fold change IC90\": 0.011980280543861745, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.0881731135190582, \"functional effect\": -0.2605, \"times_seen\": 3.0}, {\"site\": 549, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"M\", \"log2 fold change IC90\": -0.022858936840774145, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.08606935079293881, \"functional effect\": -2.5107, \"times_seen\": 4.0}, {\"site\": 549, \"mutant\": \"P\", \"log2 fold change IC90\": -0.6036199723221185, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.057546913466918204, \"functional effect\": -2.3878, \"times_seen\": 4.0}, {\"site\": 549, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -1.9556, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -3.2497, \"times_seen\": null}, {\"site\": 549, \"mutant\": \"V\", \"log2 fold change IC90\": -0.023651519714237842, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": 0.08602207929312085, \"functional effect\": -1.0027, \"times_seen\": 8.0}, {\"site\": 549, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"552\", \"IC90\": null, \"functional effect\": -3.0461, \"times_seen\": null}, {\"site\": 550, \"mutant\": \"A\", \"log2 fold change IC90\": -0.002767619207081768, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08727635827431991, \"functional effect\": -1.3807, \"times_seen\": 6.0}, {\"site\": 550, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0011687781659782254, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08751481722708433, \"functional effect\": -2.9624, \"times_seen\": 1.0}, {\"site\": 550, \"mutant\": \"I\", \"log2 fold change IC90\": -0.13204370477496818, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.07979591094079133, \"functional effect\": -1.3628, \"times_seen\": 16.0}, {\"site\": 550, \"mutant\": \"K\", \"log2 fold change IC90\": 0.005213333464354891, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08776050680669038, \"functional effect\": -0.9838, \"times_seen\": 10.0}, {\"site\": 550, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005681952129997651, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08710023260237883, \"functional effect\": -0.9395, \"times_seen\": 1.0}, {\"site\": 550, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0009606844293505632, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08738573793037405, \"functional effect\": -1.3033, \"times_seen\": 1.0}, {\"site\": 550, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": null, \"functional effect\": -2.0618, \"times_seen\": null}, {\"site\": 550, \"mutant\": \"S\", \"log2 fold change IC90\": 0.009341372765773485, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08801197895212047, \"functional effect\": -0.3906, \"times_seen\": 3.0}, {\"site\": 550, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 550, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005604112749457593, \"epitope\": \"all\", \"reference_site\": \"553\", \"IC90\": 0.08710493214792499, \"functional effect\": -1.8571, \"times_seen\": 2.0}, {\"site\": 551, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": null, \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 551, \"mutant\": \"A\", \"log2 fold change IC90\": -0.028513354249209023, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08573267564745307, \"functional effect\": 0.3314, \"times_seen\": 9.0}, {\"site\": 551, \"mutant\": \"D\", \"log2 fold change IC90\": 0.1439284581233062, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.09661766465510471, \"functional effect\": -0.0665, \"times_seen\": 22.0}, {\"site\": 551, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 551, \"mutant\": \"G\", \"log2 fold change IC90\": -0.08957947528014086, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08217952823006439, \"functional effect\": -0.3478, \"times_seen\": 28.0}, {\"site\": 551, \"mutant\": \"K\", \"log2 fold change IC90\": -0.020200154919787452, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08622811659190321, \"functional effect\": -0.0396, \"times_seen\": 25.0}, {\"site\": 551, \"mutant\": \"L\", \"log2 fold change IC90\": -0.017776647260252278, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08637308840928094, \"functional effect\": -0.8793, \"times_seen\": 3.0}, {\"site\": 551, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": null, \"functional effect\": -2.7917, \"times_seen\": null}, {\"site\": 551, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.036755681791407945, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.0897003867525553, \"functional effect\": -0.2673, \"times_seen\": 8.0}, {\"site\": 551, \"mutant\": \"R\", \"log2 fold change IC90\": -0.04228427739716331, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08491822680229126, \"functional effect\": -0.203, \"times_seen\": 8.0}, {\"site\": 551, \"mutant\": \"S\", \"log2 fold change IC90\": 0.009153640152772102, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08800052702129511, \"functional effect\": -0.2402, \"times_seen\": 1.0}, {\"site\": 551, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05382885444361135, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08424141498769232, \"functional effect\": -0.5543, \"times_seen\": 21.0}, {\"site\": 551, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0071411959116742816, \"epitope\": \"all\", \"reference_site\": \"554\", \"IC90\": 0.08701217780793447, \"functional effect\": -2.6839, \"times_seen\": 2.0}, {\"site\": 552, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -3.0124, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"G\", \"log2 fold change IC90\": -0.006832697280397751, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.08703078604266352, \"functional effect\": -2.9606, \"times_seen\": 3.0}, {\"site\": 552, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -3.1316, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": null, \"functional effect\": -1.6653, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0006093901075176103, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.08740701883205614, \"functional effect\": -2.2021, \"times_seen\": 1.0}, {\"site\": 552, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 552, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011942421776719104, \"epitope\": \"all\", \"reference_site\": \"555\", \"IC90\": 0.08672308640237321, \"functional effect\": -2.7942, \"times_seen\": 1.0}, {\"site\": 553, \"mutant\": \"D\", \"log2 fold change IC90\": -1.1231094429316901, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.04014580049967733, \"functional effect\": -0.5338, \"times_seen\": 13.0}, {\"site\": 553, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01185607721504752, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08816552291778428, \"functional effect\": -0.7417, \"times_seen\": 10.0}, {\"site\": 553, \"mutant\": \"K\", \"log2 fold change IC90\": 0.07902099367936129, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.09236712843168934, \"functional effect\": 0.306, \"times_seen\": 34.0}, {\"site\": 553, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 553, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03764599563101111, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08519167925534622, \"functional effect\": -0.7034, \"times_seen\": 8.0}, {\"site\": 553, \"mutant\": \"S\", \"log2 fold change IC90\": 0.3343807360719567, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.11025248435626091, \"functional effect\": -0.1276, \"times_seen\": 28.0}, {\"site\": 553, \"mutant\": \"T\", \"log2 fold change IC90\": -0.01521158114166263, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08652679362761184, \"functional effect\": -0.0048, \"times_seen\": 8.0}, {\"site\": 553, \"mutant\": \"V\", \"log2 fold change IC90\": -0.014910870513783115, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08654483086874977, \"functional effect\": -0.371, \"times_seen\": 3.0}, {\"site\": 553, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0011300777354730247, \"epitope\": \"all\", \"reference_site\": \"556\", \"IC90\": 0.08737547818063277, \"functional effect\": -0.3633, \"times_seen\": 9.0}, {\"site\": 554, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -2.2885, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005416496027626678, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.08711626053267427, \"functional effect\": -1.5022, \"times_seen\": 1.0}, {\"site\": 554, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -2.9281, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": null, \"functional effect\": -2.5397, \"times_seen\": null}, {\"site\": 554, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03808572849328983, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.08978312129597861, \"functional effect\": -2.5659, \"times_seen\": 1.0}, {\"site\": 554, \"mutant\": \"R\", \"log2 fold change IC90\": 0.016903067580982152, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.08847449311755269, \"functional effect\": -0.1764, \"times_seen\": 2.0}, {\"site\": 554, \"mutant\": \"T\", \"log2 fold change IC90\": -0.2492034418242998, \"epitope\": \"all\", \"reference_site\": \"557\", \"IC90\": 0.07357191184755191, \"functional effect\": -2.1692, \"times_seen\": 2.0}, {\"site\": 555, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": null, \"functional effect\": -2.0148, \"times_seen\": null}, {\"site\": 555, \"mutant\": \"E\", \"log2 fold change IC90\": -0.014981754907623653, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08654057873853775, \"functional effect\": -1.6942, \"times_seen\": 7.0}, {\"site\": 555, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 555, \"mutant\": \"M\", \"log2 fold change IC90\": -0.006648370294454446, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08704190630500672, \"functional effect\": -0.1471, \"times_seen\": 5.0}, {\"site\": 555, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03551816255599509, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08531742129635, \"functional effect\": -0.3473, \"times_seen\": 37.0}, {\"site\": 555, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004747777236927513, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08715665006914584, \"functional effect\": -0.0113, \"times_seen\": 1.0}, {\"site\": 555, \"mutant\": \"Q\", \"log2 fold change IC90\": -2.8810933004346315e-05, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08744220083912412, \"functional effect\": -0.0286, \"times_seen\": 1.0}, {\"site\": 555, \"mutant\": \"R\", \"log2 fold change IC90\": 0.026921198210540932, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08909100150010668, \"functional effect\": -0.0761, \"times_seen\": 29.0}, {\"site\": 555, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": null, \"functional effect\": -0.385, \"times_seen\": null}, {\"site\": 555, \"mutant\": \"T\", \"log2 fold change IC90\": 0.009040925030052578, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08799365196977328, \"functional effect\": -0.2543, \"times_seen\": 3.0}, {\"site\": 555, \"mutant\": \"W\", \"log2 fold change IC90\": 0.02381777219713209, \"epitope\": \"all\", \"reference_site\": \"558\", \"IC90\": 0.08889956106628359, \"functional effect\": -2.0137, \"times_seen\": 2.0}, {\"site\": 556, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0027828837274648218, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": 0.08761278471111957, \"functional effect\": -2.94, \"times_seen\": 1.0}, {\"site\": 556, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -1.1, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"L\", \"log2 fold change IC90\": 0.026131109762113754, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": 0.08904222438625121, \"functional effect\": -2.0562, \"times_seen\": 1.0}, {\"site\": 556, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -1.2662, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -2.924, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -0.4951, \"times_seen\": null}, {\"site\": 556, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"559\", \"IC90\": null, \"functional effect\": -2.585, \"times_seen\": null}, {\"site\": 557, \"mutant\": \"C\", \"log2 fold change IC90\": -0.020671140483593184, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08619997095578241, \"functional effect\": -2.3067, \"times_seen\": 1.0}, {\"site\": 557, \"mutant\": \"G\", \"log2 fold change IC90\": -0.005821036926478304, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08709183600167496, \"functional effect\": -2.8505, \"times_seen\": 1.0}, {\"site\": 557, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 557, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0295597837453942, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08567051374207099, \"functional effect\": 0.0426, \"times_seen\": 22.0}, {\"site\": 557, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0340954769706062, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08540159690511723, \"functional effect\": -2.8971, \"times_seen\": 8.0}, {\"site\": 557, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.006879999337029093, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08786195025621116, \"functional effect\": -0.1031, \"times_seen\": 9.0}, {\"site\": 557, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0003574126778434244, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08742228645189838, \"functional effect\": 0.0248, \"times_seen\": 1.0}, {\"site\": 557, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02247334679553669, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08609235767889918, \"functional effect\": -1.37, \"times_seen\": 4.0}, {\"site\": 557, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0389931864298119, \"epitope\": \"all\", \"reference_site\": \"560\", \"IC90\": 0.08511216426852591, \"functional effect\": -1.0651, \"times_seen\": 6.0}, {\"site\": 558, \"mutant\": \"A\", \"log2 fold change IC90\": 0.008633320129613233, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08796879461842294, \"functional effect\": -0.3296, \"times_seen\": 4.0}, {\"site\": 558, \"mutant\": \"G\", \"log2 fold change IC90\": 0.012230812953783662, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08818842662415188, \"functional effect\": -0.5628, \"times_seen\": 1.0}, {\"site\": 558, \"mutant\": \"H\", \"log2 fold change IC90\": 2.8488313501871856, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.6299606781154665, \"functional effect\": -0.3695, \"times_seen\": 8.0}, {\"site\": 558, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0033611679205000832, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08724045871557834, \"functional effect\": -2.3594, \"times_seen\": 5.0}, {\"site\": 558, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 558, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.018480904280103322, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08857130821950181, \"functional effect\": -0.5895, \"times_seen\": 3.0}, {\"site\": 558, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02777555727302721, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08914377651113745, \"functional effect\": -0.3134, \"times_seen\": 21.0}, {\"site\": 558, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00332552189542145, \"epitope\": \"all\", \"reference_site\": \"561\", \"IC90\": 0.08724261427438287, \"functional effect\": -0.603, \"times_seen\": 3.0}, {\"site\": 559, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 559, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": null, \"functional effect\": -3.1555, \"times_seen\": null}, {\"site\": 559, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": null, \"functional effect\": -3.0884, \"times_seen\": null}, {\"site\": 559, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0030700246955228587, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.08725806606212257, \"functional effect\": -2.9764, \"times_seen\": 2.0}, {\"site\": 559, \"mutant\": \"W\", \"log2 fold change IC90\": -0.01357208440765572, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.08662517965379364, \"functional effect\": 0.397, \"times_seen\": 1.0}, {\"site\": 559, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00539842262505032, \"epitope\": \"all\", \"reference_site\": \"562\", \"IC90\": 0.08711735189090673, \"functional effect\": -2.777, \"times_seen\": 1.0}, {\"site\": 560, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0048987823845639345, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.08714752796524734, \"functional effect\": -2.3202, \"times_seen\": 1.0}, {\"site\": 560, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": null, \"functional effect\": -2.4618, \"times_seen\": null}, {\"site\": 560, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0035991572005346657, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.08722606857700105, \"functional effect\": -2.927, \"times_seen\": 1.0}, {\"site\": 560, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 560, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005524474159977386, \"epitope\": \"all\", \"reference_site\": \"563\", \"IC90\": 0.08710974058297408, \"functional effect\": -2.9788, \"times_seen\": 1.0}, {\"site\": 561, \"mutant\": \"*\", \"log2 fold change IC90\": -0.00706658182217056, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08701667806760736, \"functional effect\": -1.592, \"times_seen\": 3.0}, {\"site\": 561, \"mutant\": \"E\", \"log2 fold change IC90\": 0.11620582464957933, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.0947787969324845, \"functional effect\": -2.4726, \"times_seen\": 5.0}, {\"site\": 561, \"mutant\": \"H\", \"log2 fold change IC90\": -0.027833666194716066, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08577307587242262, \"functional effect\": 0.2282, \"times_seen\": 5.0}, {\"site\": 561, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03213225666418002, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08941338278757681, \"functional effect\": -1.6206, \"times_seen\": 4.0}, {\"site\": 561, \"mutant\": \"L\", \"log2 fold change IC90\": 0.06078497581103518, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.09120693337859287, \"functional effect\": -0.7601, \"times_seen\": 8.0}, {\"site\": 561, \"mutant\": \"P\", \"log2 fold change IC90\": -0.00952685898583219, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.08686841200984169, \"functional effect\": -2.4087, \"times_seen\": 1.0}, {\"site\": 561, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 561, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": null, \"functional effect\": -0.38, \"times_seen\": null}, {\"site\": 561, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"564\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 562, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": null, \"functional effect\": -2.3316, \"times_seen\": null}, {\"site\": 562, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 562, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005764683834326297, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.0870952379611852, \"functional effect\": 0.2389, \"times_seen\": 2.0}, {\"site\": 562, \"mutant\": \"L\", \"log2 fold change IC90\": -0.008516277889176216, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08692928303701553, \"functional effect\": -0.4081, \"times_seen\": 10.0}, {\"site\": 562, \"mutant\": \"S\", \"log2 fold change IC90\": -0.055309060113853135, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08415502758764656, \"functional effect\": -0.9586, \"times_seen\": 3.0}, {\"site\": 562, \"mutant\": \"V\", \"log2 fold change IC90\": 0.007424506376097186, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08789511768134592, \"functional effect\": 0.2013, \"times_seen\": 7.0}, {\"site\": 562, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.009874768124152599, \"epitope\": \"all\", \"reference_site\": \"565\", \"IC90\": 0.08804452488810471, \"functional effect\": -0.0016, \"times_seen\": 6.0}, {\"site\": 563, \"mutant\": \"-\", \"log2 fold change IC90\": -0.015513051783082835, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.08650871457279521, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 563, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04147895059824677, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.08496564223833698, \"functional effect\": -1.6099, \"times_seen\": 7.0}, {\"site\": 563, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": null, \"functional effect\": -2.9434, \"times_seen\": null}, {\"site\": 563, \"mutant\": \"D\", \"log2 fold change IC90\": -0.7183096405835285, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.05314923339902365, \"functional effect\": -2.1732, \"times_seen\": 2.0}, {\"site\": 563, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 563, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": null, \"functional effect\": -0.5665, \"times_seen\": null}, {\"site\": 563, \"mutant\": \"S\", \"log2 fold change IC90\": -0.1306995457866597, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": 0.07987029143682381, \"functional effect\": -0.7948, \"times_seen\": 21.0}, {\"site\": 563, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"566\", \"IC90\": null, \"functional effect\": -2.3366, \"times_seen\": null}, {\"site\": 564, \"mutant\": \"-\", \"log2 fold change IC90\": -0.002531490496912766, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08729064413510709, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 564, \"mutant\": \"G\", \"log2 fold change IC90\": -0.02558808221301644, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08590668735562772, \"functional effect\": -2.5503, \"times_seen\": 9.0}, {\"site\": 564, \"mutant\": \"I\", \"log2 fold change IC90\": 0.004091774975505987, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08769230785327796, \"functional effect\": -0.1, \"times_seen\": 11.0}, {\"site\": 564, \"mutant\": \"K\", \"log2 fold change IC90\": 0.8656443116551606, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.15933627364092312, \"functional effect\": 0.0704, \"times_seen\": 30.0}, {\"site\": 564, \"mutant\": \"M\", \"log2 fold change IC90\": 0.008114577580439939, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08793716981039587, \"functional effect\": -0.4411, \"times_seen\": 11.0}, {\"site\": 564, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00273951960693203, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.08727805818634836, \"functional effect\": -0.3508, \"times_seen\": 4.0}, {\"site\": 564, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 564, \"mutant\": \"S\", \"log2 fold change IC90\": -0.17370084799240884, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.07752478800364603, \"functional effect\": -1.2128, \"times_seen\": 8.0}, {\"site\": 564, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": null, \"functional effect\": -0.4161, \"times_seen\": null}, {\"site\": 564, \"mutant\": \"W\", \"log2 fold change IC90\": 5.427990486862203e-05, \"epitope\": \"all\", \"reference_site\": \"567\", \"IC90\": 0.0874472371460086, \"functional effect\": -0.1585, \"times_seen\": 3.0}, {\"site\": 565, \"mutant\": \"-\", \"log2 fold change IC90\": -0.005013986351903883, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.08714056922494648, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 565, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 565, \"mutant\": \"E\", \"log2 fold change IC90\": -0.009394979796580315, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.08687635316098663, \"functional effect\": -1.9319, \"times_seen\": 3.0}, {\"site\": 565, \"mutant\": \"G\", \"log2 fold change IC90\": -0.01221076113913592, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.08670695752344945, \"functional effect\": -1.7188, \"times_seen\": 8.0}, {\"site\": 565, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 565, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": null, \"functional effect\": -1.5973, \"times_seen\": null}, {\"site\": 565, \"mutant\": \"N\", \"log2 fold change IC90\": -0.024481152967502334, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": 0.08597262583317895, \"functional effect\": -2.0757, \"times_seen\": 9.0}, {\"site\": 565, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"568\", \"IC90\": null, \"functional effect\": -3.0982, \"times_seen\": null}, {\"site\": 566, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004759095185245832, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08715596632756233, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 566, \"mutant\": \"F\", \"log2 fold change IC90\": -0.02429810089640986, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08598353490627691, \"functional effect\": -1.2127, \"times_seen\": 11.0}, {\"site\": 566, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 566, \"mutant\": \"L\", \"log2 fold change IC90\": -0.026255499536103875, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.0858669545295799, \"functional effect\": 0.0508, \"times_seen\": 7.0}, {\"site\": 566, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": null, \"functional effect\": -1.5911, \"times_seen\": null}, {\"site\": 566, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01421158301237457, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08658679010921529, \"functional effect\": -0.8953, \"times_seen\": 9.0}, {\"site\": 566, \"mutant\": \"T\", \"log2 fold change IC90\": 0.008395983172748962, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08795432411136363, \"functional effect\": -0.4726, \"times_seen\": 6.0}, {\"site\": 566, \"mutant\": \"V\", \"log2 fold change IC90\": 0.008033000798796456, \"epitope\": \"all\", \"reference_site\": \"569\", \"IC90\": 0.08793219756866423, \"functional effect\": -0.0367, \"times_seen\": 23.0}, {\"site\": 567, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0005803828359145685, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08740877628221208, \"functional effect\": -2.7409, \"times_seen\": 2.0}, {\"site\": 567, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004164524062761838, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.0871918929087051, \"functional effect\": -0.4621, \"times_seen\": 1.0}, {\"site\": 567, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 567, \"mutant\": \"C\", \"log2 fold change IC90\": 0.09843274730411847, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.09361834564357334, \"functional effect\": -2.8571, \"times_seen\": 7.0}, {\"site\": 567, \"mutant\": \"D\", \"log2 fold change IC90\": -0.05314245627411032, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08428150447922747, \"functional effect\": -2.3645, \"times_seen\": 13.0}, {\"site\": 567, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004848411522529259, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08715057072384574, \"functional effect\": -2.8609, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"F\", \"log2 fold change IC90\": 0.011346719374078067, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08813440069687911, \"functional effect\": -2.2365, \"times_seen\": 14.0}, {\"site\": 567, \"mutant\": \"G\", \"log2 fold change IC90\": -0.17697005372257896, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.07734931256842341, \"functional effect\": -1.323, \"times_seen\": 63.0}, {\"site\": 567, \"mutant\": \"H\", \"log2 fold change IC90\": -0.008124484897266394, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.0869528936462895, \"functional effect\": -2.6726, \"times_seen\": 2.0}, {\"site\": 567, \"mutant\": \"I\", \"log2 fold change IC90\": 0.11168241728334113, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.09448209410096432, \"functional effect\": -2.3606, \"times_seen\": 8.0}, {\"site\": 567, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03428441813626113, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.0895468660498883, \"functional effect\": -2.0229, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"L\", \"log2 fold change IC90\": 0.05188599984461975, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.09064607319747459, \"functional effect\": -2.2957, \"times_seen\": 14.0}, {\"site\": 567, \"mutant\": \"M\", \"log2 fold change IC90\": 0.011658584882154427, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08815345465485522, \"functional effect\": -2.9093, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"N\", \"log2 fold change IC90\": -0.002632161907084429, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08728455319738594, \"functional effect\": -2.6227, \"times_seen\": 2.0}, {\"site\": 567, \"mutant\": \"P\", \"log2 fold change IC90\": -0.010547176080791334, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08680699778951656, \"functional effect\": -2.4414, \"times_seen\": 7.0}, {\"site\": 567, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.020388548064675664, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.0862168572994039, \"functional effect\": -2.5472, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00023186758402972404, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.0874298943776241, \"functional effect\": -2.621, \"times_seen\": 11.0}, {\"site\": 567, \"mutant\": \"S\", \"log2 fold change IC90\": 1.0289991289170262, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.1784388255514495, \"functional effect\": -0.1169, \"times_seen\": 140.0}, {\"site\": 567, \"mutant\": \"T\", \"log2 fold change IC90\": 0.42307184367421036, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.11724303928113683, \"functional effect\": 0.0316, \"times_seen\": 138.0}, {\"site\": 567, \"mutant\": \"V\", \"log2 fold change IC90\": -0.6304860768056595, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.0564851819258161, \"functional effect\": -1.4471, \"times_seen\": 88.0}, {\"site\": 567, \"mutant\": \"W\", \"log2 fold change IC90\": -0.008611891083803589, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08692352207519945, \"functional effect\": -2.4598, \"times_seen\": 4.0}, {\"site\": 567, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03823620181654885, \"epitope\": \"all\", \"reference_site\": \"570\", \"IC90\": 0.08515683448834525, \"functional effect\": -1.6172, \"times_seen\": 34.0}, {\"site\": 568, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 568, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0492666128347931, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.0904816436247706, \"functional effect\": -0.0272, \"times_seen\": 14.0}, {\"site\": 568, \"mutant\": \"G\", \"log2 fold change IC90\": -0.046993926718728665, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.08464146492424705, \"functional effect\": 0.0333, \"times_seen\": 23.0}, {\"site\": 568, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": null, \"functional effect\": -2.0259, \"times_seen\": null}, {\"site\": 568, \"mutant\": \"N\", \"log2 fold change IC90\": -0.021097985791510444, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.08617447103405738, \"functional effect\": -3.0583, \"times_seen\": 2.0}, {\"site\": 568, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.8315882012534581, \"epitope\": \"all\", \"reference_site\": \"571\", \"IC90\": 0.049135656181410935, \"functional effect\": -2.0572, \"times_seen\": 20.0}, {\"site\": 569, \"mutant\": \"*\", \"log2 fold change IC90\": -0.023728872490448034, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08601746718309151, \"functional effect\": -2.7558, \"times_seen\": 1.0}, {\"site\": 569, \"mutant\": \"A\", \"log2 fold change IC90\": -0.033941017998246344, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08541074072878209, \"functional effect\": 0.1502, \"times_seen\": 45.0}, {\"site\": 569, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02181044463458409, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08613192523963474, \"functional effect\": -1.1717, \"times_seen\": 13.0}, {\"site\": 569, \"mutant\": \"D\", \"log2 fold change IC90\": 0.025379552857892725, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08899585084997372, \"functional effect\": -1.2113, \"times_seen\": 7.0}, {\"site\": 569, \"mutant\": \"E\", \"log2 fold change IC90\": 0.007860458613295238, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08792168175909536, \"functional effect\": -1.2738, \"times_seen\": 12.0}, {\"site\": 569, \"mutant\": \"F\", \"log2 fold change IC90\": 0.043435093945883005, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.09011664586962706, \"functional effect\": -0.1425, \"times_seen\": 5.0}, {\"site\": 569, \"mutant\": \"G\", \"log2 fold change IC90\": 0.2643309418968721, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.10502708093660336, \"functional effect\": -0.3767, \"times_seen\": 51.0}, {\"site\": 569, \"mutant\": \"H\", \"log2 fold change IC90\": -1.293319650762182, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.035678102098352274, \"functional effect\": 0.3283, \"times_seen\": 17.0}, {\"site\": 569, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06010056031936441, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.09116367501014763, \"functional effect\": -1.2776, \"times_seen\": 28.0}, {\"site\": 569, \"mutant\": \"K\", \"log2 fold change IC90\": -1.3972951620994103, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.033197241378315985, \"functional effect\": 0.401, \"times_seen\": 12.0}, {\"site\": 569, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0971774100017999, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.09353692061417478, \"functional effect\": -1.1166, \"times_seen\": 24.0}, {\"site\": 569, \"mutant\": \"M\", \"log2 fold change IC90\": -0.036784431172339885, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08524257015165611, \"functional effect\": -0.0921, \"times_seen\": 16.0}, {\"site\": 569, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0005089170506166691, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08741310629748529, \"functional effect\": -1.2249, \"times_seen\": 48.0}, {\"site\": 569, \"mutant\": \"P\", \"log2 fold change IC90\": -0.013097947536675423, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08665365340626599, \"functional effect\": -2.7875, \"times_seen\": 2.0}, {\"site\": 569, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01698257084064992, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08642064226495752, \"functional effect\": 0.3372, \"times_seen\": 13.0}, {\"site\": 569, \"mutant\": \"R\", \"log2 fold change IC90\": -0.20925572866250797, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.07563755848202984, \"functional effect\": -0.6641, \"times_seen\": 53.0}, {\"site\": 569, \"mutant\": \"S\", \"log2 fold change IC90\": -0.09179995288013022, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08205314154331035, \"functional effect\": 0.1456, \"times_seen\": 57.0}, {\"site\": 569, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 569, \"mutant\": \"V\", \"log2 fold change IC90\": -0.11807792781251607, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08057211329310114, \"functional effect\": -0.7735, \"times_seen\": 19.0}, {\"site\": 569, \"mutant\": \"W\", \"log2 fold change IC90\": 0.04167622127814541, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.09000684641818997, \"functional effect\": -0.502, \"times_seen\": 13.0}, {\"site\": 569, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.028532011017011156, \"epitope\": \"all\", \"reference_site\": \"572\", \"IC90\": 0.08573156696943375, \"functional effect\": -0.0262, \"times_seen\": 19.0}, {\"site\": 570, \"mutant\": \"A\", \"log2 fold change IC90\": -0.010163069313995798, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08683011258050692, \"functional effect\": -1.4135, \"times_seen\": 8.0}, {\"site\": 570, \"mutant\": \"I\", \"log2 fold change IC90\": -0.035066314794075785, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08534414664186747, \"functional effect\": 0.2755, \"times_seen\": 31.0}, {\"site\": 570, \"mutant\": \"K\", \"log2 fold change IC90\": -0.017483260515604265, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08639065504348761, \"functional effect\": -1.3074, \"times_seen\": 3.0}, {\"site\": 570, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014130522303266755, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.08659165529804083, \"functional effect\": 0.2203, \"times_seen\": 4.0}, {\"site\": 570, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": null, \"functional effect\": -1.5474, \"times_seen\": null}, {\"site\": 570, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": null, \"functional effect\": -1.3033, \"times_seen\": null}, {\"site\": 570, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": null, \"functional effect\": -1.4348, \"times_seen\": null}, {\"site\": 570, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"573\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 571, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 571, \"mutant\": \"E\", \"log2 fold change IC90\": -0.00329273154422996, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08724459719411992, \"functional effect\": -2.1183, \"times_seen\": 1.0}, {\"site\": 571, \"mutant\": \"G\", \"log2 fold change IC90\": -0.006326243503496507, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.08706134330287149, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 571, \"mutant\": \"H\", \"log2 fold change IC90\": -0.03563699410824535, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.0853103941812688, \"functional effect\": -1.7645, \"times_seen\": 6.0}, {\"site\": 571, \"mutant\": \"N\", \"log2 fold change IC90\": -0.09621798726072057, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08180225061703983, \"functional effect\": 0.397, \"times_seen\": 41.0}, {\"site\": 571, \"mutant\": \"V\", \"log2 fold change IC90\": 0.01755010793746922, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.08851418231398026, \"functional effect\": -0.6174, \"times_seen\": 5.0}, {\"site\": 571, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02591786633523441, \"epitope\": \"all\", \"reference_site\": \"574\", \"IC90\": 0.0890290641096015, \"functional effect\": -2.0659, \"times_seen\": 16.0}, {\"site\": 572, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 572, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": null, \"functional effect\": -3.0047, \"times_seen\": null}, {\"site\": 572, \"mutant\": \"G\", \"log2 fold change IC90\": 0.004110360144698306, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.08769343753545594, \"functional effect\": -2.1062, \"times_seen\": 7.0}, {\"site\": 572, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": null, \"functional effect\": 0.7078, \"times_seen\": null}, {\"site\": 572, \"mutant\": \"S\", \"log2 fold change IC90\": -1.3260036038768235, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.03487890914486814, \"functional effect\": 0.1167, \"times_seen\": 57.0}, {\"site\": 572, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03647643171172749, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.08526077044182401, \"functional effect\": -1.6023, \"times_seen\": 29.0}, {\"site\": 572, \"mutant\": \"V\", \"log2 fold change IC90\": -0.007185682133689471, \"epitope\": \"all\", \"reference_site\": \"575\", \"IC90\": 0.08700949478534742, \"functional effect\": -2.2746, \"times_seen\": 11.0}, {\"site\": 573, \"mutant\": \"A\", \"log2 fold change IC90\": -0.002689871098378234, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08728106180101235, \"functional effect\": -2.0367, \"times_seen\": 1.0}, {\"site\": 573, \"mutant\": \"F\", \"log2 fold change IC90\": 0.000749988364129395, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08748941685281215, \"functional effect\": -2.8705, \"times_seen\": 1.0}, {\"site\": 573, \"mutant\": \"I\", \"log2 fold change IC90\": -0.018339957020601417, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.0863393700524585, \"functional effect\": 0.2586, \"times_seen\": 25.0}, {\"site\": 573, \"mutant\": \"L\", \"log2 fold change IC90\": 0.028719720042471652, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08920213519371828, \"functional effect\": -0.7482, \"times_seen\": 4.0}, {\"site\": 573, \"mutant\": \"M\", \"log2 fold change IC90\": 0.010074962135132329, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.08805674313871525, \"functional effect\": -1.4259, \"times_seen\": 4.0}, {\"site\": 573, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"576\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 574, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": null, \"functional effect\": -2.8795, \"times_seen\": null}, {\"site\": 574, \"mutant\": \"G\", \"log2 fold change IC90\": 0.004442391043064628, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08771362217659917, \"functional effect\": -2.4292, \"times_seen\": 5.0}, {\"site\": 574, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01953285991815191, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08626800922244639, \"functional effect\": -0.2346, \"times_seen\": 17.0}, {\"site\": 574, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05642665335557579, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08408986158361934, \"functional effect\": -1.9766, \"times_seen\": 2.0}, {\"site\": 574, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02174231256138216, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08613599296360916, \"functional effect\": -2.1163, \"times_seen\": 10.0}, {\"site\": 574, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 574, \"mutant\": \"S\", \"log2 fold change IC90\": -0.007048764873233079, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08701775271002264, \"functional effect\": -2.9583, \"times_seen\": 2.0}, {\"site\": 574, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0055337236203065535, \"epitope\": \"all\", \"reference_site\": \"577\", \"IC90\": 0.08710918210354207, \"functional effect\": -1.2552, \"times_seen\": 1.0}, {\"site\": 575, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -2.9763, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -3.0225, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -3.085, \"times_seen\": null}, {\"site\": 575, \"mutant\": \"N\", \"log2 fold change IC90\": -0.006398057957891059, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": 0.0870570096723529, \"functional effect\": -2.333, \"times_seen\": 2.0}, {\"site\": 575, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"578\", \"IC90\": null, \"functional effect\": -2.8685, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": null, \"functional effect\": -1.6729, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0034053610540180565, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": 0.08723778637660087, \"functional effect\": -0.8443, \"times_seen\": 1.0}, {\"site\": 576, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.025495829962896715, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": 0.08900302395075317, \"functional effect\": -2.2045, \"times_seen\": 1.0}, {\"site\": 576, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": null, \"functional effect\": -2.1658, \"times_seen\": null}, {\"site\": 576, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"579\", \"IC90\": null, \"functional effect\": -2.6607, \"times_seen\": null}, {\"site\": 577, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": null, \"functional effect\": -2.4574, \"times_seen\": null}, {\"site\": 577, \"mutant\": \"E\", \"log2 fold change IC90\": -0.00997727593260776, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.0868412954698886, \"functional effect\": -0.9949, \"times_seen\": 5.0}, {\"site\": 577, \"mutant\": \"H\", \"log2 fold change IC90\": -0.08479940760074178, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08245226445254333, \"functional effect\": -1.1274, \"times_seen\": 22.0}, {\"site\": 577, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004611723102212956, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08716486981166237, \"functional effect\": -0.185, \"times_seen\": 9.0}, {\"site\": 577, \"mutant\": \"L\", \"log2 fold change IC90\": -0.10208854686919908, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.08147006034668239, \"functional effect\": 0.0657, \"times_seen\": 53.0}, {\"site\": 577, \"mutant\": \"M\", \"log2 fold change IC90\": -0.037276308322769694, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.0852135122257311, \"functional effect\": 0.2053, \"times_seen\": 5.0}, {\"site\": 577, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 577, \"mutant\": \"R\", \"log2 fold change IC90\": -0.1295343839920651, \"epitope\": \"all\", \"reference_site\": \"580\", \"IC90\": 0.07993482302477321, \"functional effect\": -0.0238, \"times_seen\": 44.0}, {\"site\": 578, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": null, \"functional effect\": 0.0867, \"times_seen\": null}, {\"site\": 578, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01520537108658954, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": 0.08837044167816338, \"functional effect\": -2.5045, \"times_seen\": 5.0}, {\"site\": 578, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": null, \"functional effect\": -0.8684, \"times_seen\": null}, {\"site\": 578, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05956548030803204, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": 0.08390710875108448, \"functional effect\": -0.5312, \"times_seen\": 20.0}, {\"site\": 578, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"581\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 579, \"mutant\": \"F\", \"log2 fold change IC90\": -1.1156439135306448, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.04035408183435329, \"functional effect\": 0.0603, \"times_seen\": 48.0}, {\"site\": 579, \"mutant\": \"H\", \"log2 fold change IC90\": -0.020308920801923872, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08622161603331228, \"functional effect\": 0.3607, \"times_seen\": 3.0}, {\"site\": 579, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 579, \"mutant\": \"M\", \"log2 fold change IC90\": -0.010575237772435095, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08680530933322822, \"functional effect\": -0.0263, \"times_seen\": 2.0}, {\"site\": 579, \"mutant\": \"S\", \"log2 fold change IC90\": 0.035004783931253884, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.08959158971281109, \"functional effect\": 0.3336, \"times_seen\": 6.0}, {\"site\": 579, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04250911020683463, \"epitope\": \"all\", \"reference_site\": \"582\", \"IC90\": 0.09005882368803997, \"functional effect\": -3.2007, \"times_seen\": 1.0}, {\"site\": 580, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": null, \"functional effect\": -1.4807, \"times_seen\": null}, {\"site\": 580, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": null, \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 580, \"mutant\": \"A\", \"log2 fold change IC90\": -0.014888112393539972, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08654619610058777, \"functional effect\": -1.1563, \"times_seen\": 3.0}, {\"site\": 580, \"mutant\": \"D\", \"log2 fold change IC90\": -0.02550205665992546, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08591180998405631, \"functional effect\": -1.0418, \"times_seen\": 15.0}, {\"site\": 580, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 580, \"mutant\": \"G\", \"log2 fold change IC90\": -0.007717241244514836, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08697744215543327, \"functional effect\": -2.4049, \"times_seen\": 2.0}, {\"site\": 580, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03618952437816072, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08966519249867866, \"functional effect\": -1.3008, \"times_seen\": 17.0}, {\"site\": 580, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0050909220846993295, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08713592233520055, \"functional effect\": -3.0176, \"times_seen\": 1.0}, {\"site\": 580, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06255355256878084, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08373350238707473, \"functional effect\": -0.8469, \"times_seen\": 12.0}, {\"site\": 580, \"mutant\": \"V\", \"log2 fold change IC90\": 0.012581905712867731, \"epitope\": \"all\", \"reference_site\": \"583\", \"IC90\": 0.08820989067922204, \"functional effect\": -2.1047, \"times_seen\": 4.0}, {\"site\": 581, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": null, \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"F\", \"log2 fold change IC90\": 0.021440254278944183, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08875317792133706, \"functional effect\": -2.627, \"times_seen\": 1.0}, {\"site\": 581, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013420051719688918, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08663430878537454, \"functional effect\": -2.6452, \"times_seen\": 3.0}, {\"site\": 581, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": null, \"functional effect\": -3.0759, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": null, \"functional effect\": -3.2738, \"times_seen\": null}, {\"site\": 581, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003391491951789012, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08723862502618297, \"functional effect\": -2.0253, \"times_seen\": 1.0}, {\"site\": 581, \"mutant\": \"V\", \"log2 fold change IC90\": -0.023872521873462952, \"epitope\": \"all\", \"reference_site\": \"584\", \"IC90\": 0.08600890283608999, \"functional effect\": 0.3752, \"times_seen\": 9.0}, {\"site\": 582, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": null, \"functional effect\": -0.8585, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0021260476985492396, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08731517900598158, \"functional effect\": -1.1432, \"times_seen\": 16.0}, {\"site\": 582, \"mutant\": \"I\", \"log2 fold change IC90\": -0.16970802770964039, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.07773964372815034, \"functional effect\": -0.1092, \"times_seen\": 11.0}, {\"site\": 582, \"mutant\": \"K\", \"log2 fold change IC90\": -0.024641858551161768, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08596304965031676, \"functional effect\": -2.8776, \"times_seen\": 2.0}, {\"site\": 582, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"M\", \"log2 fold change IC90\": 0.010351106690874816, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08807359958921879, \"functional effect\": -0.8359, \"times_seen\": 14.0}, {\"site\": 582, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": null, \"functional effect\": -3.0671, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": null, \"functional effect\": -1.8692, \"times_seen\": null}, {\"site\": 582, \"mutant\": \"V\", \"log2 fold change IC90\": -0.00381228603169715, \"epitope\": \"all\", \"reference_site\": \"585\", \"IC90\": 0.08721318365232356, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 583, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 583, \"mutant\": \"E\", \"log2 fold change IC90\": 0.038507507270767564, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08980937365710799, \"functional effect\": -1.4963, \"times_seen\": 6.0}, {\"site\": 583, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0075936227913704435, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08698489520490915, \"functional effect\": -1.31, \"times_seen\": 2.0}, {\"site\": 583, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": null, \"functional effect\": -1.6565, \"times_seen\": null}, {\"site\": 583, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": null, \"functional effect\": -3.0571, \"times_seen\": null}, {\"site\": 583, \"mutant\": \"N\", \"log2 fold change IC90\": -0.046717415289562525, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.0846576891260267, \"functional effect\": -0.2218, \"times_seen\": 14.0}, {\"site\": 583, \"mutant\": \"S\", \"log2 fold change IC90\": -0.022532428003215164, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.086088832099223, \"functional effect\": -0.7711, \"times_seen\": 6.0}, {\"site\": 583, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0049234329391031105, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08714603893501059, \"functional effect\": -0.6072, \"times_seen\": 3.0}, {\"site\": 583, \"mutant\": \"W\", \"log2 fold change IC90\": -0.019359431066040385, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": 0.08627838027155302, \"functional effect\": -2.9842, \"times_seen\": 2.0}, {\"site\": 583, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"586\", \"IC90\": null, \"functional effect\": -1.7541, \"times_seen\": null}, {\"site\": 584, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": null, \"functional effect\": -3.0614, \"times_seen\": null}, {\"site\": 584, \"mutant\": \"G\", \"log2 fold change IC90\": -0.003779239275567687, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08721518140357329, \"functional effect\": -2.9847, \"times_seen\": 1.0}, {\"site\": 584, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 584, \"mutant\": \"L\", \"log2 fold change IC90\": -0.012991295133071406, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08666005958481923, \"functional effect\": -1.7824, \"times_seen\": 2.0}, {\"site\": 584, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007277270616257009, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08700397122394288, \"functional effect\": -2.7277, \"times_seen\": 1.0}, {\"site\": 584, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004404085161315021, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.08717741580097667, \"functional effect\": -2.2331, \"times_seen\": 2.0}, {\"site\": 584, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011790766360531418, \"epitope\": \"all\", \"reference_site\": \"587\", \"IC90\": 0.0867322031711152, \"functional effect\": -1.6721, \"times_seen\": 3.0}, {\"site\": 585, \"mutant\": \"A\", \"log2 fold change IC90\": 0.10130758602177785, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.09380508363654036, \"functional effect\": -0.7151, \"times_seen\": 14.0}, {\"site\": 585, \"mutant\": \"I\", \"log2 fold change IC90\": -0.9432915496996614, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.045474789949202045, \"functional effect\": -1.1483, \"times_seen\": 22.0}, {\"site\": 585, \"mutant\": \"K\", \"log2 fold change IC90\": -0.044327750516097546, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.0847980314236012, \"functional effect\": -0.6462, \"times_seen\": 10.0}, {\"site\": 585, \"mutant\": \"R\", \"log2 fold change IC90\": -0.014067368679058435, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08659544590963776, \"functional effect\": 0.0031, \"times_seen\": 3.0}, {\"site\": 585, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013558304051666756, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08662600708542717, \"functional effect\": -0.4023, \"times_seen\": 5.0}, {\"site\": 585, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 585, \"mutant\": \"V\", \"log2 fold change IC90\": -0.013514340553116988, \"epitope\": \"all\", \"reference_site\": \"588\", \"IC90\": 0.08662864689512796, \"functional effect\": -0.4268, \"times_seen\": 5.0}, {\"site\": 586, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": null, \"functional effect\": -2.6176, \"times_seen\": null}, {\"site\": 586, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004446994159926369, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08717482298691706, \"functional effect\": -2.8352, \"times_seen\": 1.0}, {\"site\": 586, \"mutant\": \"L\", \"log2 fold change IC90\": -0.008579246285292599, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08692548897249093, \"functional effect\": -2.9777, \"times_seen\": 2.0}, {\"site\": 586, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 586, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0010621489135465428, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08737959232316683, \"functional effect\": -2.5671, \"times_seen\": 2.0}, {\"site\": 586, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": null, \"functional effect\": -2.9764, \"times_seen\": null}, {\"site\": 586, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0364765375030878, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": 0.08968303247624546, \"functional effect\": -2.3969, \"times_seen\": 5.0}, {\"site\": 586, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"589\", \"IC90\": null, \"functional effect\": -2.5191, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": null, \"functional effect\": -2.9546, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"L\", \"log2 fold change IC90\": -0.006318570147363989, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.08706180636294324, \"functional effect\": -2.9043, \"times_seen\": 1.0}, {\"site\": 587, \"mutant\": \"R\", \"log2 fold change IC90\": -0.012572987800719583, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.08668519018638246, \"functional effect\": -2.9197, \"times_seen\": 3.0}, {\"site\": 587, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": null, \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 587, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004863647152710371, \"epitope\": \"all\", \"reference_site\": \"590\", \"IC90\": 0.08714965037213114, \"functional effect\": -2.9917, \"times_seen\": 1.0}, {\"site\": 588, \"mutant\": \"A\", \"log2 fold change IC90\": 0.03839355218945317, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08980228010648955, \"functional effect\": -0.3383, \"times_seen\": 4.0}, {\"site\": 588, \"mutant\": \"C\", \"log2 fold change IC90\": -0.001499247367018385, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08735312262696397, \"functional effect\": -0.936, \"times_seen\": 1.0}, {\"site\": 588, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0329245038908961, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08547094182079737, \"functional effect\": -1.3641, \"times_seen\": 28.0}, {\"site\": 588, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03822505943407343, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08979179268562701, \"functional effect\": 0.07, \"times_seen\": 6.0}, {\"site\": 588, \"mutant\": \"L\", \"log2 fold change IC90\": -0.006213746152996939, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08706813236919939, \"functional effect\": -1.8018, \"times_seen\": 2.0}, {\"site\": 588, \"mutant\": \"P\", \"log2 fold change IC90\": 0.021789165907258646, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08877464521684472, \"functional effect\": -1.303, \"times_seen\": 6.0}, {\"site\": 588, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 588, \"mutant\": \"T\", \"log2 fold change IC90\": 0.039268048820324676, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08985673069735953, \"functional effect\": -0.2819, \"times_seen\": 10.0}, {\"site\": 588, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0030657354133345697, \"epitope\": \"all\", \"reference_site\": \"591\", \"IC90\": 0.08725832548980085, \"functional effect\": -1.843, \"times_seen\": 3.0}, {\"site\": 589, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 589, \"mutant\": \"I\", \"log2 fold change IC90\": -1.033637197139166, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.04271436474521026, \"functional effect\": -2.971, \"times_seen\": 2.0}, {\"site\": 589, \"mutant\": \"L\", \"log2 fold change IC90\": -0.025158750337594828, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.08593225614641467, \"functional effect\": -2.4882, \"times_seen\": 4.0}, {\"site\": 589, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 589, \"mutant\": \"P\", \"log2 fold change IC90\": -0.008001006698784218, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.08696033613818288, \"functional effect\": -2.8179, \"times_seen\": 1.0}, {\"site\": 589, \"mutant\": \"S\", \"log2 fold change IC90\": 0.006694893525750018, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.08785067780167219, \"functional effect\": -0.25, \"times_seen\": 20.0}, {\"site\": 589, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": null, \"functional effect\": -2.9925, \"times_seen\": null}, {\"site\": 589, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04825948103930026, \"epitope\": \"all\", \"reference_site\": \"592\", \"IC90\": 0.09041850128519587, \"functional effect\": -0.2666, \"times_seen\": 2.0}, {\"site\": 590, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": null, \"functional effect\": -3.1088, \"times_seen\": null}, {\"site\": 590, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": null, \"functional effect\": -1.8569, \"times_seen\": null}, {\"site\": 590, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0058115804502735634, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08709240686700036, \"functional effect\": -1.2492, \"times_seen\": 1.0}, {\"site\": 590, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005692799539771616, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08709957771112618, \"functional effect\": -2.9055, \"times_seen\": 1.0}, {\"site\": 590, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 590, \"mutant\": \"R\", \"log2 fold change IC90\": -0.033418282665619116, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08544169342512098, \"functional effect\": -2.2234, \"times_seen\": 8.0}, {\"site\": 590, \"mutant\": \"S\", \"log2 fold change IC90\": -0.016426283680303334, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08645397152862244, \"functional effect\": -1.7069, \"times_seen\": 5.0}, {\"site\": 590, \"mutant\": \"V\", \"log2 fold change IC90\": -0.09136417017967874, \"epitope\": \"all\", \"reference_site\": \"593\", \"IC90\": 0.08207793038612965, \"functional effect\": -1.6035, \"times_seen\": 7.0}, {\"site\": 591, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0016583962397803483, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.087544522817532, \"functional effect\": -2.0412, \"times_seen\": 2.0}, {\"site\": 591, \"mutant\": \"D\", \"log2 fold change IC90\": 0.005561236074306059, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08778167260415509, \"functional effect\": -1.2151, \"times_seen\": 5.0}, {\"site\": 591, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0025056370153709127, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08729220842084595, \"functional effect\": -0.7032, \"times_seen\": 10.0}, {\"site\": 591, \"mutant\": \"F\", \"log2 fold change IC90\": 0.011180147769223974, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08812422540641415, \"functional effect\": -0.9029, \"times_seen\": 6.0}, {\"site\": 591, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 591, \"mutant\": \"R\", \"log2 fold change IC90\": 0.007073845275877352, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08787375651188227, \"functional effect\": -0.7007, \"times_seen\": 17.0}, {\"site\": 591, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004057990945222756, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08719833166871938, \"functional effect\": 0.0355, \"times_seen\": 13.0}, {\"site\": 591, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0037003771815586534, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08721994898066253, \"functional effect\": -2.1905, \"times_seen\": 6.0}, {\"site\": 591, \"mutant\": \"W\", \"log2 fold change IC90\": -0.008216828259775332, \"epitope\": \"all\", \"reference_site\": \"594\", \"IC90\": 0.08694732818347019, \"functional effect\": -1.4738, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"A\", \"log2 fold change IC90\": -0.029202872076055913, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08569171059085151, \"functional effect\": -0.8661, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"E\", \"log2 fold change IC90\": 0.028253872030365407, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08917333636383515, \"functional effect\": -2.6389, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"G\", \"log2 fold change IC90\": -0.002483147896752551, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.0872935691658925, \"functional effect\": -0.5895, \"times_seen\": 1.0}, {\"site\": 592, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04610390007388523, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.09028350472630213, \"functional effect\": -0.1331, \"times_seen\": 6.0}, {\"site\": 592, \"mutant\": \"L\", \"log2 fold change IC90\": -0.004810341842326061, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08715287047399262, \"functional effect\": -0.7692, \"times_seen\": 5.0}, {\"site\": 592, \"mutant\": \"M\", \"log2 fold change IC90\": -0.006470729905183235, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.08705262451617037, \"functional effect\": -3.0332, \"times_seen\": 2.0}, {\"site\": 592, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"595\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 593, \"mutant\": \"A\", \"log2 fold change IC90\": -0.006793323158673167, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08703316132463818, \"functional effect\": -0.0969, \"times_seen\": 2.0}, {\"site\": 593, \"mutant\": \"C\", \"log2 fold change IC90\": -0.011518803141969588, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08674855464657527, \"functional effect\": -1.042, \"times_seen\": 7.0}, {\"site\": 593, \"mutant\": \"F\", \"log2 fold change IC90\": -0.016504430299964176, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.0864492886937445, \"functional effect\": -0.651, \"times_seen\": 3.0}, {\"site\": 593, \"mutant\": \"I\", \"log2 fold change IC90\": -0.014275431897639, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08658295815059869, \"functional effect\": -2.2683, \"times_seen\": 3.0}, {\"site\": 593, \"mutant\": \"N\", \"log2 fold change IC90\": -0.01886194315901567, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08630813697756597, \"functional effect\": -0.941, \"times_seen\": 4.0}, {\"site\": 593, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": null, \"functional effect\": -2.9489, \"times_seen\": null}, {\"site\": 593, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005902768611794252, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08708690220714017, \"functional effect\": -1.3007, \"times_seen\": 4.0}, {\"site\": 593, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 593, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00858779147227135, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08692497410806316, \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 593, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03762141045754159, \"epitope\": \"all\", \"reference_site\": \"596\", \"IC90\": 0.08519313103136217, \"functional effect\": -1.4555, \"times_seen\": 2.0}, {\"site\": 594, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 594, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0041664041922170915, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.08719177927974357, \"functional effect\": -1.6931, \"times_seen\": 2.0}, {\"site\": 594, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": null, \"functional effect\": -3.0615, \"times_seen\": null}, {\"site\": 594, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04413801603515275, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.09016056396280848, \"functional effect\": -0.7923, \"times_seen\": 7.0}, {\"site\": 594, \"mutant\": \"L\", \"log2 fold change IC90\": -0.004210486059957187, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.0871891151562433, \"functional effect\": -1.8609, \"times_seen\": 1.0}, {\"site\": 594, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": null, \"functional effect\": -2.8088, \"times_seen\": null}, {\"site\": 594, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"597\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"L\", \"log2 fold change IC90\": -0.006405592363337435, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.0870565550224952, \"functional effect\": -1.5147, \"times_seen\": 1.0}, {\"site\": 595, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": null, \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": null, \"functional effect\": -3.2609, \"times_seen\": null}, {\"site\": 595, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004341420577185547, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.08718120250225239, \"functional effect\": -2.1948, \"times_seen\": 1.0}, {\"site\": 595, \"mutant\": \"V\", \"log2 fold change IC90\": -0.009478482942732397, \"epitope\": \"all\", \"reference_site\": \"598\", \"IC90\": 0.08687132490576292, \"functional effect\": -0.7859, \"times_seen\": 17.0}, {\"site\": 596, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 596, \"mutant\": \"A\", \"log2 fold change IC90\": -0.009116985210284515, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.08689309507953348, \"functional effect\": -2.4833, \"times_seen\": 2.0}, {\"site\": 596, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": null, \"functional effect\": -2.6075, \"times_seen\": null}, {\"site\": 596, \"mutant\": \"I\", \"log2 fold change IC90\": -0.07008806957401471, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.08329734164669922, \"functional effect\": -1.9985, \"times_seen\": 11.0}, {\"site\": 596, \"mutant\": \"K\", \"log2 fold change IC90\": -0.00509127544219392, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.08713590099311053, \"functional effect\": -2.6961, \"times_seen\": 1.0}, {\"site\": 596, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": null, \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 596, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"599\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": null, \"functional effect\": -2.6041, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02611021609350404, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.0890409348515926, \"functional effect\": 0.3906, \"times_seen\": 2.0}, {\"site\": 597, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": null, \"functional effect\": -3.0462, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01597559854387381, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.08648098320150659, \"functional effect\": -2.586, \"times_seen\": 5.0}, {\"site\": 597, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": null, \"functional effect\": -2.9775, \"times_seen\": null}, {\"site\": 597, \"mutant\": \"S\", \"log2 fold change IC90\": -0.009405370694652929, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.08687572744310854, \"functional effect\": -2.9757, \"times_seen\": 2.0}, {\"site\": 597, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004566990819974256, \"epitope\": \"all\", \"reference_site\": \"600\", \"IC90\": 0.08716757249233668, \"functional effect\": -2.8966, \"times_seen\": 1.0}, {\"site\": 598, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0021565626175938653, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.08757475739038598, \"functional effect\": -2.6823, \"times_seen\": 1.0}, {\"site\": 598, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01693602012022315, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.08642343080165239, \"functional effect\": -3.0564, \"times_seen\": 4.0}, {\"site\": 598, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 598, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0042696111775957805, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": 0.08718554200951982, \"functional effect\": -2.9556, \"times_seen\": 1.0}, {\"site\": 598, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": null, \"functional effect\": -3.237, \"times_seen\": null}, {\"site\": 598, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"601\", \"IC90\": null, \"functional effect\": -2.1284, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": null, \"functional effect\": -2.3607, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": null, \"functional effect\": -1.7296, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011973137181689419, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.08672124006181753, \"functional effect\": -1.4786, \"times_seen\": 1.0}, {\"site\": 599, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0054130555455597, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.08711646828433417, \"functional effect\": -2.3935, \"times_seen\": 1.0}, {\"site\": 599, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": null, \"functional effect\": -3.0817, \"times_seen\": null}, {\"site\": 599, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005290634377722617, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.08712386094320212, \"functional effect\": -0.1275, \"times_seen\": 1.0}, {\"site\": 599, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"602\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 600, \"mutant\": \"D\", \"log2 fold change IC90\": -0.012802714053713048, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.0866713880466591, \"functional effect\": 0.1276, \"times_seen\": 8.0}, {\"site\": 600, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0022133484329124736, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08757820448192723, \"functional effect\": -0.5201, \"times_seen\": 9.0}, {\"site\": 600, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01924243595956396, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08628537728568494, \"functional effect\": -0.5396, \"times_seen\": 6.0}, {\"site\": 600, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02573512093791366, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.08589793223709659, \"functional effect\": 0.0118, \"times_seen\": 13.0}, {\"site\": 600, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 600, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005055301059503282, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.0871380738011137, \"functional effect\": 0.0945, \"times_seen\": 1.0}, {\"site\": 600, \"mutant\": \"S\", \"log2 fold change IC90\": 0.07106940871648988, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.09185943642713665, \"functional effect\": -0.2211, \"times_seen\": 19.0}, {\"site\": 600, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0233037100899605, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": 0.0860428202765181, \"functional effect\": -0.2757, \"times_seen\": 20.0}, {\"site\": 600, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"603\", \"IC90\": null, \"functional effect\": -0.8372, \"times_seen\": null}, {\"site\": 601, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04628457225944068, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08468309226886525, \"functional effect\": -0.1977, \"times_seen\": 32.0}, {\"site\": 601, \"mutant\": \"I\", \"log2 fold change IC90\": -0.031097776673058655, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.085579232886876, \"functional effect\": 0.0939, \"times_seen\": 76.0}, {\"site\": 601, \"mutant\": \"N\", \"log2 fold change IC90\": -0.04031251029170891, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08503436599675267, \"functional effect\": -0.4228, \"times_seen\": 44.0}, {\"site\": 601, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0064011066897560415, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08705682570194231, \"functional effect\": -0.5434, \"times_seen\": 2.0}, {\"site\": 601, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 601, \"mutant\": \"V\", \"log2 fold change IC90\": -0.006286592338096204, \"epitope\": \"all\", \"reference_site\": \"604\", \"IC90\": 0.08706373613785363, \"functional effect\": 0.0637, \"times_seen\": 6.0}, {\"site\": 602, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0002791146796639023, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08742703116618698, \"functional effect\": -1.6258, \"times_seen\": 8.0}, {\"site\": 602, \"mutant\": \"C\", \"log2 fold change IC90\": -0.004629428319385527, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08716380010293227, \"functional effect\": -1.3301, \"times_seen\": 2.0}, {\"site\": 602, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0070768936569659815, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08701605610774997, \"functional effect\": -2.9726, \"times_seen\": 1.0}, {\"site\": 602, \"mutant\": \"G\", \"log2 fold change IC90\": -0.007404315261860452, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.0869963099360705, \"functional effect\": -1.7384, \"times_seen\": 6.0}, {\"site\": 602, \"mutant\": \"I\", \"log2 fold change IC90\": -0.006440529485632859, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08705444683705328, \"functional effect\": 0.1573, \"times_seen\": 1.0}, {\"site\": 602, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": null, \"functional effect\": -3.1345, \"times_seen\": null}, {\"site\": 602, \"mutant\": \"N\", \"log2 fold change IC90\": -0.009392268332546277, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.08687651644035038, \"functional effect\": -2.5998, \"times_seen\": 3.0}, {\"site\": 602, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": null, \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 602, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 602, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"605\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"D\", \"log2 fold change IC90\": -0.014114285925378809, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.08659262982329315, \"functional effect\": 0.0398, \"times_seen\": 19.0}, {\"site\": 603, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": null, \"functional effect\": -0.133, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"K\", \"log2 fold change IC90\": 0.06092383025949804, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.09121571215549835, \"functional effect\": -0.9545, \"times_seen\": 7.0}, {\"site\": 603, \"mutant\": \"L\", \"log2 fold change IC90\": -0.004013324551236248, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.08720103140443643, \"functional effect\": -0.7121, \"times_seen\": 1.0}, {\"site\": 603, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 603, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07413046268213694, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.08306427139312413, \"functional effect\": -0.0215, \"times_seen\": 10.0}, {\"site\": 603, \"mutant\": \"T\", \"log2 fold change IC90\": 0.003584645137944408, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.08766148805470704, \"functional effect\": -0.4306, \"times_seen\": 17.0}, {\"site\": 603, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00515316487474519, \"epitope\": \"all\", \"reference_site\": \"606\", \"IC90\": 0.0871321630750857, \"functional effect\": -1.1502, \"times_seen\": 6.0}, {\"site\": 604, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0065094163917228595, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.0870502901939903, \"functional effect\": -2.9643, \"times_seen\": 1.0}, {\"site\": 604, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": null, \"functional effect\": -0.3317, \"times_seen\": null}, {\"site\": 604, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06337461268599215, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08368586191030476, \"functional effect\": -0.374, \"times_seen\": 56.0}, {\"site\": 604, \"mutant\": \"K\", \"log2 fold change IC90\": -0.10063407062696919, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08155223711717487, \"functional effect\": -0.0725, \"times_seen\": 54.0}, {\"site\": 604, \"mutant\": \"L\", \"log2 fold change IC90\": -0.026315813377689654, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.0858633648190099, \"functional effect\": -0.1144, \"times_seen\": 16.0}, {\"site\": 604, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 604, \"mutant\": \"R\", \"log2 fold change IC90\": 0.006841978805941988, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08785963478835512, \"functional effect\": -0.2201, \"times_seen\": 38.0}, {\"site\": 604, \"mutant\": \"V\", \"log2 fold change IC90\": -0.07858740750902027, \"epitope\": \"all\", \"reference_site\": \"607\", \"IC90\": 0.08280805535311145, \"functional effect\": 0.0911, \"times_seen\": 15.0}, {\"site\": 605, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": null, \"functional effect\": -1.4881, \"times_seen\": null}, {\"site\": 605, \"mutant\": \"D\", \"log2 fold change IC90\": -0.008291724872623548, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08694281448434409, \"functional effect\": -0.6953, \"times_seen\": 2.0}, {\"site\": 605, \"mutant\": \"F\", \"log2 fold change IC90\": -0.00935054712319956, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08687902885332555, \"functional effect\": -0.2404, \"times_seen\": 7.0}, {\"site\": 605, \"mutant\": \"I\", \"log2 fold change IC90\": 0.029215926266541896, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08923282100481318, \"functional effect\": -0.1307, \"times_seen\": 20.0}, {\"site\": 605, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02641864066608423, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.08905997238011494, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 605, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": null, \"functional effect\": -2.9968, \"times_seen\": null}, {\"site\": 605, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"608\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": null, \"functional effect\": -2.843, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": null, \"functional effect\": -2.0465, \"times_seen\": null}, {\"site\": 606, \"mutant\": \"S\", \"log2 fold change IC90\": -0.12627842453960136, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.0801154283824477, \"functional effect\": -2.4976, \"times_seen\": 7.0}, {\"site\": 606, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00448423259203646, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.08717257288433808, \"functional effect\": -2.2921, \"times_seen\": 2.0}, {\"site\": 606, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0014594705637953765, \"epitope\": \"all\", \"reference_site\": \"609\", \"IC90\": 0.08735553108874654, \"functional effect\": -2.7193, \"times_seen\": 5.0}, {\"site\": 607, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": null, \"functional effect\": -3.0487, \"times_seen\": null}, {\"site\": 607, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": null, \"functional effect\": -3.2443, \"times_seen\": null}, {\"site\": 607, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": null, \"functional effect\": -2.9958, \"times_seen\": null}, {\"site\": 607, \"mutant\": \"I\", \"log2 fold change IC90\": -0.008075840073139329, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.08695582557535979, \"functional effect\": -0.3049, \"times_seen\": 3.0}, {\"site\": 607, \"mutant\": \"L\", \"log2 fold change IC90\": -0.016337704166778856, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.08645927984786177, \"functional effect\": -1.1414, \"times_seen\": 12.0}, {\"site\": 607, \"mutant\": \"M\", \"log2 fold change IC90\": 0.02514934275700958, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.08898165096108568, \"functional effect\": -2.8599, \"times_seen\": 1.0}, {\"site\": 607, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"610\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 608, \"mutant\": \"F\", \"log2 fold change IC90\": 0.8500391966813444, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.1576220779330493, \"functional effect\": -0.9023, \"times_seen\": 84.0}, {\"site\": 608, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012738338817180835, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.08667525554147433, \"functional effect\": -1.4612, \"times_seen\": 4.0}, {\"site\": 608, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 608, \"mutant\": \"P\", \"log2 fold change IC90\": 0.006223430477348866, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.08782197348072776, \"functional effect\": -2.9813, \"times_seen\": 1.0}, {\"site\": 608, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0002921973588476182, \"epitope\": \"all\", \"reference_site\": \"611\", \"IC90\": 0.08746165941754727, \"functional effect\": -1.9878, \"times_seen\": 2.0}, {\"site\": 609, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0053702970121719765, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": 0.08711905027672551, \"functional effect\": -2.9522, \"times_seen\": 1.0}, {\"site\": 609, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.9547, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0001830069496467952, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": 0.08743285546941569, \"functional effect\": -0.6197, \"times_seen\": 6.0}, {\"site\": 609, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.7929, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.9456, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": null, \"functional effect\": -2.9307, \"times_seen\": null}, {\"site\": 609, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"612\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 610, \"mutant\": \"*\", \"log2 fold change IC90\": -0.023258708547657086, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08604550422558388, \"functional effect\": -2.5233, \"times_seen\": 1.0}, {\"site\": 610, \"mutant\": \"E\", \"log2 fold change IC90\": 0.05086203852576577, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.09058175943834003, \"functional effect\": -0.0633, \"times_seen\": 17.0}, {\"site\": 610, \"mutant\": \"H\", \"log2 fold change IC90\": 0.009068862467740574, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08799535596188643, \"functional effect\": 0.0786, \"times_seen\": 18.0}, {\"site\": 610, \"mutant\": \"K\", \"log2 fold change IC90\": -0.041422421625559085, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08496897150365829, \"functional effect\": -1.4795, \"times_seen\": 11.0}, {\"site\": 610, \"mutant\": \"L\", \"log2 fold change IC90\": -0.027494116597363616, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.08579326561462426, \"functional effect\": -1.6206, \"times_seen\": 5.0}, {\"site\": 610, \"mutant\": \"P\", \"log2 fold change IC90\": 0.013349721534263273, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.0882568493045279, \"functional effect\": -1.1987, \"times_seen\": 2.0}, {\"site\": 610, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 610, \"mutant\": \"R\", \"log2 fold change IC90\": -1.4007585125685298, \"epitope\": \"all\", \"reference_site\": \"613\", \"IC90\": 0.033117643275436565, \"functional effect\": -0.1161, \"times_seen\": 60.0}, {\"site\": 611, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005617227600713051, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08710414032220713, \"functional effect\": -1.5617, \"times_seen\": 1.0}, {\"site\": 611, \"mutant\": \"A\", \"log2 fold change IC90\": -0.010232197405770149, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08682595213355307, \"functional effect\": -0.7202, \"times_seen\": 18.0}, {\"site\": 611, \"mutant\": \"C\", \"log2 fold change IC90\": -0.013539260006446627, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08662715058452977, \"functional effect\": -2.8353, \"times_seen\": 2.0}, {\"site\": 611, \"mutant\": \"D\", \"log2 fold change IC90\": -1.0947043835819454, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.04094405924728018, \"functional effect\": -0.1259, \"times_seen\": 15.0}, {\"site\": 611, \"mutant\": \"E\", \"log2 fold change IC90\": -0.008568674897092014, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08692612592377248, \"functional effect\": -1.4898, \"times_seen\": 3.0}, {\"site\": 611, \"mutant\": \"F\", \"log2 fold change IC90\": 0.08190598573921203, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.09255202201205225, \"functional effect\": -3.0182, \"times_seen\": 2.0}, {\"site\": 611, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 611, \"mutant\": \"H\", \"log2 fold change IC90\": -0.010997978639598305, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08677987722537187, \"functional effect\": -0.6028, \"times_seen\": 2.0}, {\"site\": 611, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05824954695286178, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08398367831885575, \"functional effect\": -1.8835, \"times_seen\": 1.0}, {\"site\": 611, \"mutant\": \"K\", \"log2 fold change IC90\": -0.017630475683731595, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08638184003713903, \"functional effect\": -1.5818, \"times_seen\": 6.0}, {\"site\": 611, \"mutant\": \"L\", \"log2 fold change IC90\": 1.3111422608065313, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.2169815972979886, \"functional effect\": -1.0809, \"times_seen\": 10.0}, {\"site\": 611, \"mutant\": \"M\", \"log2 fold change IC90\": -0.009966060586008874, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.0868419705668328, \"functional effect\": -1.0646, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"N\", \"log2 fold change IC90\": -3.9738409233837793, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.005565246906219255, \"functional effect\": 0.1571, \"times_seen\": 11.0}, {\"site\": 611, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0013467378611131374, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08736235734765854, \"functional effect\": -3.008, \"times_seen\": 1.0}, {\"site\": 611, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.004397063441350838, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08771086637196904, \"functional effect\": -0.9781, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"R\", \"log2 fold change IC90\": 1.6702830105563622, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.27831399173040705, \"functional effect\": -1.5402, \"times_seen\": 21.0}, {\"site\": 611, \"mutant\": \"S\", \"log2 fold change IC90\": 0.2967585099062073, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.10741451349670972, \"functional effect\": -0.612, \"times_seen\": 38.0}, {\"site\": 611, \"mutant\": \"T\", \"log2 fold change IC90\": -0.11336945168415893, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.08083550341161833, \"functional effect\": -1.6407, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01296888344279208, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.0866614058246313, \"functional effect\": -2.6495, \"times_seen\": 7.0}, {\"site\": 611, \"mutant\": \"W\", \"log2 fold change IC90\": -0.01862247600928735, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": 0.0863224641072542, \"functional effect\": -2.742, \"times_seen\": 5.0}, {\"site\": 611, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"614\", \"IC90\": null, \"functional effect\": -2.8327, \"times_seen\": null}, {\"site\": 612, \"mutant\": \"A\", \"log2 fold change IC90\": 0.04107429132350075, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08996930105009736, \"functional effect\": -0.5794, \"times_seen\": 13.0}, {\"site\": 612, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005943076888755605, \"epitope\": \"all\", \"reference_site\": null, \"IC90\": 0.08708446907065853, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 612, \"mutant\": \"F\", \"log2 fold change IC90\": -0.002483211954810154, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08729356528991303, \"functional effect\": -1.6823, \"times_seen\": 6.0}, {\"site\": 612, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": null, \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 612, \"mutant\": \"I\", \"log2 fold change IC90\": 0.022325386956733015, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08880764711931527, \"functional effect\": 0.0285, \"times_seen\": 15.0}, {\"site\": 612, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01967832373672021, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08864485185135043, \"functional effect\": -0.5605, \"times_seen\": 8.0}, {\"site\": 612, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01066304238264546, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.08680002639109666, \"functional effect\": -0.132, \"times_seen\": 26.0}, {\"site\": 612, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"615\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 613, \"mutant\": \"D\", \"log2 fold change IC90\": -0.019809855462504872, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.08625144746846637, \"functional effect\": -0.0954, \"times_seen\": 12.0}, {\"site\": 613, \"mutant\": \"K\", \"log2 fold change IC90\": 0.1024980888223237, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.09388252294361818, \"functional effect\": 0.045, \"times_seen\": 50.0}, {\"site\": 613, \"mutant\": \"L\", \"log2 fold change IC90\": -0.012126381022305205, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.08671202897442226, \"functional effect\": 0.2989, \"times_seen\": 4.0}, {\"site\": 613, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 613, \"mutant\": \"S\", \"log2 fold change IC90\": 0.020437659533358726, \"epitope\": \"all\", \"reference_site\": \"616\", \"IC90\": 0.08869152070679262, \"functional effect\": 0.0998, \"times_seen\": 9.0}, {\"site\": 614, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -2.8497, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -2.5949, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0028095887528836573, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": 0.08727381934839783, \"functional effect\": -2.5849, \"times_seen\": 1.0}, {\"site\": 614, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -1.2614, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": null, \"functional effect\": -3.132, \"times_seen\": null}, {\"site\": 614, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.026917634728185768, \"epitope\": \"all\", \"reference_site\": \"617\", \"IC90\": 0.0890907814440236, \"functional effect\": -2.6836, \"times_seen\": 2.0}, {\"site\": 615, \"mutant\": \"A\", \"log2 fold change IC90\": -0.025323619405846466, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.08592243649561644, \"functional effect\": 0.2089, \"times_seen\": 30.0}, {\"site\": 615, \"mutant\": \"I\", \"log2 fold change IC90\": -0.6994932287980753, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.05384697481945788, \"functional effect\": -0.0548, \"times_seen\": 30.0}, {\"site\": 615, \"mutant\": \"K\", \"log2 fold change IC90\": 0.04463190074050122, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.09019143434433351, \"functional effect\": 0.2881, \"times_seen\": 13.0}, {\"site\": 615, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0662024169440502, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.09155006692356656, \"functional effect\": 0.3502, \"times_seen\": 6.0}, {\"site\": 615, \"mutant\": \"R\", \"log2 fold change IC90\": 0.001809442792922243, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.08755368898937739, \"functional effect\": -0.3306, \"times_seen\": 10.0}, {\"site\": 615, \"mutant\": \"S\", \"log2 fold change IC90\": 0.016643571764595758, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.08845858074833277, \"functional effect\": -0.0955, \"times_seen\": 8.0}, {\"site\": 615, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"618\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 616, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": null, \"functional effect\": -1.4132, \"times_seen\": null}, {\"site\": 616, \"mutant\": \"A\", \"log2 fold change IC90\": 0.051967320576673005, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.09065118281009402, \"functional effect\": -0.506, \"times_seen\": 6.0}, {\"site\": 616, \"mutant\": \"D\", \"log2 fold change IC90\": 0.026842011714181768, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.08908611161661929, \"functional effect\": -0.3661, \"times_seen\": 28.0}, {\"site\": 616, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 616, \"mutant\": \"G\", \"log2 fold change IC90\": 0.005048686351717509, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.08775049173826076, \"functional effect\": -1.2736, \"times_seen\": 19.0}, {\"site\": 616, \"mutant\": \"K\", \"log2 fold change IC90\": 0.541430491050347, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.1272672239930644, \"functional effect\": -0.7037, \"times_seen\": 39.0}, {\"site\": 616, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09658394842117471, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.09349845153274175, \"functional effect\": -0.3618, \"times_seen\": 15.0}, {\"site\": 616, \"mutant\": \"R\", \"log2 fold change IC90\": 0.016799712766838337, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.08846815502322694, \"functional effect\": -0.6991, \"times_seen\": 4.0}, {\"site\": 616, \"mutant\": \"V\", \"log2 fold change IC90\": -0.053708304802045026, \"epitope\": \"all\", \"reference_site\": \"619\", \"IC90\": 0.08424845438020853, \"functional effect\": -1.0595, \"times_seen\": 10.0}, {\"site\": 617, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": null, \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 617, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": null, \"functional effect\": -2.1861, \"times_seen\": null}, {\"site\": 617, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009366170922493361, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.0868780879939469, \"functional effect\": -2.9745, \"times_seen\": 2.0}, {\"site\": 617, \"mutant\": \"I\", \"log2 fold change IC90\": -0.007848324704382691, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.08696953973269057, \"functional effect\": -1.8411, \"times_seen\": 2.0}, {\"site\": 617, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0030771242059168293, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.08763065533242338, \"functional effect\": -1.49, \"times_seen\": 7.0}, {\"site\": 617, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02424926039415394, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.0859864458125989, \"functional effect\": -1.9799, \"times_seen\": 4.0}, {\"site\": 617, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"620\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": null, \"functional effect\": -3.0646, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01208898424407693, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08671427670693271, \"functional effect\": 0.2404, \"times_seen\": 2.0}, {\"site\": 618, \"mutant\": \"G\", \"log2 fold change IC90\": -0.013595572830277397, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08662376932644898, \"functional effect\": -0.185, \"times_seen\": 1.0}, {\"site\": 618, \"mutant\": \"H\", \"log2 fold change IC90\": -0.09221130632404233, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08202974919086568, \"functional effect\": -0.2754, \"times_seen\": 13.0}, {\"site\": 618, \"mutant\": \"L\", \"log2 fold change IC90\": -1.6560354145944567, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.027746832927521645, \"functional effect\": -1.4398, \"times_seen\": 9.0}, {\"site\": 618, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": null, \"functional effect\": -0.3843, \"times_seen\": null}, {\"site\": 618, \"mutant\": \"R\", \"log2 fold change IC90\": -0.021864589395960816, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08612869274427366, \"functional effect\": -0.8676, \"times_seen\": 2.0}, {\"site\": 618, \"mutant\": \"S\", \"log2 fold change IC90\": 0.037625530663084016, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08975448640971914, \"functional effect\": 0.0839, \"times_seen\": 21.0}, {\"site\": 618, \"mutant\": \"T\", \"log2 fold change IC90\": -0.040961121710777135, \"epitope\": \"all\", \"reference_site\": \"621\", \"IC90\": 0.08499614456888344, \"functional effect\": -0.8725, \"times_seen\": 11.0}, {\"site\": 619, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0037792519750165154, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08721518063585405, \"functional effect\": -2.9006, \"times_seen\": 1.0}, {\"site\": 619, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": null, \"functional effect\": -2.2694, \"times_seen\": null}, {\"site\": 619, \"mutant\": \"A\", \"log2 fold change IC90\": 0.14410155183872358, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.09662925748198689, \"functional effect\": -0.2054, \"times_seen\": 74.0}, {\"site\": 619, \"mutant\": \"C\", \"log2 fold change IC90\": -0.07687923225169395, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08290615955413787, \"functional effect\": -0.7004, \"times_seen\": 16.0}, {\"site\": 619, \"mutant\": \"D\", \"log2 fold change IC90\": -0.05833822765125176, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.0839785161035997, \"functional effect\": 0.1215, \"times_seen\": 25.0}, {\"site\": 619, \"mutant\": \"E\", \"log2 fold change IC90\": -0.06853512348744328, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.0833870528627968, \"functional effect\": -0.0828, \"times_seen\": 46.0}, {\"site\": 619, \"mutant\": \"F\", \"log2 fold change IC90\": 0.7170974963828104, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.14374660920774388, \"functional effect\": -0.0222, \"times_seen\": 48.0}, {\"site\": 619, \"mutant\": \"G\", \"log2 fold change IC90\": -0.5462771845430421, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.059880295427883014, \"functional effect\": 0.3922, \"times_seen\": 90.0}, {\"site\": 619, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0008542611504821188, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08749574050036153, \"functional effect\": 0.0315, \"times_seen\": 9.0}, {\"site\": 619, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04865077776079326, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08454431493865959, \"functional effect\": -0.0573, \"times_seen\": 17.0}, {\"site\": 619, \"mutant\": \"K\", \"log2 fold change IC90\": 0.008547679506420245, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.0879635728088392, \"functional effect\": -0.264, \"times_seen\": 19.0}, {\"site\": 619, \"mutant\": \"L\", \"log2 fold change IC90\": 0.2859370456726278, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.10661182566263978, \"functional effect\": 0.0054, \"times_seen\": 110.0}, {\"site\": 619, \"mutant\": \"M\", \"log2 fold change IC90\": -0.08003067149637683, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08272525606414859, \"functional effect\": 0.0884, \"times_seen\": 33.0}, {\"site\": 619, \"mutant\": \"N\", \"log2 fold change IC90\": 0.03357548779983637, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08950287415055917, \"functional effect\": -0.078, \"times_seen\": 19.0}, {\"site\": 619, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0010767441704072154, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08737870833791202, \"functional effect\": -0.457, \"times_seen\": 24.0}, {\"site\": 619, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004224259116857107, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08718828278704681, \"functional effect\": 0.0915, \"times_seen\": 20.0}, {\"site\": 619, \"mutant\": \"R\", \"log2 fold change IC90\": -1.7684285317370714, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.02566727239415965, \"functional effect\": -0.3886, \"times_seen\": 66.0}, {\"site\": 619, \"mutant\": \"S\", \"log2 fold change IC90\": -0.12562867410736686, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08015151830899979, \"functional effect\": 0.1195, \"times_seen\": 47.0}, {\"site\": 619, \"mutant\": \"T\", \"log2 fold change IC90\": -0.010200060327953087, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.08682788626611729, \"functional effect\": 0.0777, \"times_seen\": 22.0}, {\"site\": 619, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 619, \"mutant\": \"W\", \"log2 fold change IC90\": 0.06922318022534336, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.09174195834958584, \"functional effect\": -0.0497, \"times_seen\": 19.0}, {\"site\": 619, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.2924468643072999, \"epitope\": \"all\", \"reference_site\": \"622\", \"IC90\": 0.07139938558216247, \"functional effect\": -0.0704, \"times_seen\": 15.0}, {\"site\": 620, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": null, \"functional effect\": -1.736, \"times_seen\": null}, {\"site\": 620, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 620, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": null, \"functional effect\": -1.2151, \"times_seen\": null}, {\"site\": 620, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010380846655686421, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08681700641225137, \"functional effect\": 0.2509, \"times_seen\": 2.0}, {\"site\": 620, \"mutant\": \"S\", \"log2 fold change IC90\": -0.10573872765870397, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08126419247103416, \"functional effect\": -0.1413, \"times_seen\": 17.0}, {\"site\": 620, \"mutant\": \"T\", \"log2 fold change IC90\": 0.007872204720473702, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08792239760109394, \"functional effect\": -0.205, \"times_seen\": 43.0}, {\"site\": 620, \"mutant\": \"V\", \"log2 fold change IC90\": 0.029657124729062335, \"epitope\": \"all\", \"reference_site\": \"623\", \"IC90\": 0.08926011395503113, \"functional effect\": -0.3156, \"times_seen\": 48.0}, {\"site\": 621, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": null, \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 621, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 621, \"mutant\": \"L\", \"log2 fold change IC90\": 0.006233782916211966, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08782260367272783, \"functional effect\": 0.197, \"times_seen\": 1.0}, {\"site\": 621, \"mutant\": \"M\", \"log2 fold change IC90\": -0.009067861919837774, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08689605381114157, \"functional effect\": 0.3237, \"times_seen\": 3.0}, {\"site\": 621, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": null, \"functional effect\": -2.6612, \"times_seen\": null}, {\"site\": 621, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0011386669204734258, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.087374957986211, \"functional effect\": -1.5897, \"times_seen\": 6.0}, {\"site\": 621, \"mutant\": \"V\", \"log2 fold change IC90\": -0.024464683028739165, \"epitope\": \"all\", \"reference_site\": \"624\", \"IC90\": 0.08597360731015438, \"functional effect\": -0.3589, \"times_seen\": 14.0}, {\"site\": 622, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": null, \"functional effect\": 0.7168, \"times_seen\": null}, {\"site\": 622, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 622, \"mutant\": \"L\", \"log2 fold change IC90\": -0.10077241592659308, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.0815444171500836, \"functional effect\": -0.6508, \"times_seen\": 5.0}, {\"site\": 622, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004003299349808782, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08720163736128604, \"functional effect\": 0.0723, \"times_seen\": 10.0}, {\"site\": 622, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.025980382669412574, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.0890329220914745, \"functional effect\": -0.2539, \"times_seen\": 6.0}, {\"site\": 622, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0444236116960979, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08479239712871176, \"functional effect\": 0.3651, \"times_seen\": 27.0}, {\"site\": 622, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.047732578504038885, \"epitope\": \"all\", \"reference_site\": \"625\", \"IC90\": 0.08459814005998503, \"functional effect\": -1.0128, \"times_seen\": 9.0}, {\"site\": 623, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 623, \"mutant\": \"D\", \"log2 fold change IC90\": -0.023889618103364426, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08600788361912286, \"functional effect\": -0.1853, \"times_seen\": 5.0}, {\"site\": 623, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 623, \"mutant\": \"P\", \"log2 fold change IC90\": 0.023080318563008923, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08885413043153252, \"functional effect\": -2.37, \"times_seen\": 1.0}, {\"site\": 623, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09019998280680232, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.09308563233042398, \"functional effect\": -0.8131, \"times_seen\": 6.0}, {\"site\": 623, \"mutant\": \"R\", \"log2 fold change IC90\": -0.006801627761277837, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08703266033605951, \"functional effect\": -1.9877, \"times_seen\": 5.0}, {\"site\": 623, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0022683996816242687, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08758154640892361, \"functional effect\": 0.0731, \"times_seen\": 20.0}, {\"site\": 623, \"mutant\": \"T\", \"log2 fold change IC90\": -0.020421263636403293, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08621490220722013, \"functional effect\": -0.301, \"times_seen\": 33.0}, {\"site\": 623, \"mutant\": \"V\", \"log2 fold change IC90\": -0.11911680341959542, \"epitope\": \"all\", \"reference_site\": \"626\", \"IC90\": 0.08051411470679871, \"functional effect\": -0.1941, \"times_seen\": 52.0}, {\"site\": 624, \"mutant\": \"A\", \"log2 fold change IC90\": 0.14217529515143917, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.0965003261811113, \"functional effect\": -0.0542, \"times_seen\": 8.0}, {\"site\": 624, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 624, \"mutant\": \"E\", \"log2 fold change IC90\": 0.07842282565180991, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.09232883925138034, \"functional effect\": 0.2853, \"times_seen\": 32.0}, {\"site\": 624, \"mutant\": \"G\", \"log2 fold change IC90\": 0.040443964420689524, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08993000121021645, \"functional effect\": -0.3528, \"times_seen\": 29.0}, {\"site\": 624, \"mutant\": \"H\", \"log2 fold change IC90\": 0.20573765067069463, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.10084699386484763, \"functional effect\": -0.0033, \"times_seen\": 33.0}, {\"site\": 624, \"mutant\": \"N\", \"log2 fold change IC90\": 0.00830466470023668, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08794875703023441, \"functional effect\": -0.1129, \"times_seen\": 25.0}, {\"site\": 624, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0003907217365097107, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08746763254392886, \"functional effect\": 0.3301, \"times_seen\": 1.0}, {\"site\": 624, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": null, \"functional effect\": -1.7134, \"times_seen\": null}, {\"site\": 624, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0023071896730134643, \"epitope\": \"all\", \"reference_site\": \"627\", \"IC90\": 0.08758390126078551, \"functional effect\": -1.169, \"times_seen\": 23.0}, {\"site\": 625, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": null, \"functional effect\": -1.9116, \"times_seen\": null}, {\"site\": 625, \"mutant\": \"E\", \"log2 fold change IC90\": 0.01479310308123486, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.08834519233599841, \"functional effect\": -0.1243, \"times_seen\": 4.0}, {\"site\": 625, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0017006142933262433, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.0873409309982522, \"functional effect\": -1.7745, \"times_seen\": 1.0}, {\"site\": 625, \"mutant\": \"K\", \"log2 fold change IC90\": 0.07943027092378112, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.09239333572117045, \"functional effect\": 0.3651, \"times_seen\": 24.0}, {\"site\": 625, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06876242653798612, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.08337391589491468, \"functional effect\": -0.5072, \"times_seen\": 30.0}, {\"site\": 625, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": null, \"functional effect\": -2.8236, \"times_seen\": null}, {\"site\": 625, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 625, \"mutant\": \"R\", \"log2 fold change IC90\": 0.04563074633955563, \"epitope\": \"all\", \"reference_site\": \"628\", \"IC90\": 0.09025389973566979, \"functional effect\": -0.0393, \"times_seen\": 4.0}, {\"site\": 626, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005672058197886643, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08710082993356717, \"functional effect\": 0.2464, \"times_seen\": 1.0}, {\"site\": 626, \"mutant\": \"F\", \"log2 fold change IC90\": -0.00954735236680919, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08686717805895963, \"functional effect\": -2.3288, \"times_seen\": 3.0}, {\"site\": 626, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01075767859548586, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08679433277177652, \"functional effect\": -2.041, \"times_seen\": 2.0}, {\"site\": 626, \"mutant\": \"I\", \"log2 fold change IC90\": -0.037468849608801924, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08520214043614811, \"functional effect\": -0.1729, \"times_seen\": 6.0}, {\"site\": 626, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 626, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": null, \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 626, \"mutant\": \"V\", \"log2 fold change IC90\": 0.011055407769643666, \"epitope\": \"all\", \"reference_site\": \"629\", \"IC90\": 0.08811660623513116, \"functional effect\": 0.0994, \"times_seen\": 4.0}, {\"site\": 627, \"mutant\": \"A\", \"log2 fold change IC90\": 0.003765038225561105, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08767244984132286, \"functional effect\": -0.4191, \"times_seen\": 13.0}, {\"site\": 627, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": null, \"functional effect\": -2.6515, \"times_seen\": null}, {\"site\": 627, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02445942021889002, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08597392093400404, \"functional effect\": -2.566, \"times_seen\": 4.0}, {\"site\": 627, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0014217770394573041, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08753016564865197, \"functional effect\": -3.0079, \"times_seen\": 1.0}, {\"site\": 627, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": null, \"functional effect\": -0.6732, \"times_seen\": null}, {\"site\": 627, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02486806546323492, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08594957215779624, \"functional effect\": -1.4567, \"times_seen\": 5.0}, {\"site\": 627, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0028436168503216184, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.08761647302352617, \"functional effect\": -0.2781, \"times_seen\": 6.0}, {\"site\": 627, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"630\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 628, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": null, \"functional effect\": -2.5612, \"times_seen\": null}, {\"site\": 628, \"mutant\": \"H\", \"log2 fold change IC90\": -0.05383089292880226, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08424129595716215, \"functional effect\": -0.7566, \"times_seen\": 6.0}, {\"site\": 628, \"mutant\": \"L\", \"log2 fold change IC90\": -0.042567559784656296, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08490155420292386, \"functional effect\": -1.2904, \"times_seen\": 14.0}, {\"site\": 628, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 628, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.011831372845491751, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08816401320509365, \"functional effect\": -0.4117, \"times_seen\": 1.0}, {\"site\": 628, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03912398955013243, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08510444785467898, \"functional effect\": -0.6186, \"times_seen\": 17.0}, {\"site\": 628, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03142655296371822, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.08555973242684635, \"functional effect\": -0.7441, \"times_seen\": 10.0}, {\"site\": 628, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.034976628843515024, \"epitope\": \"all\", \"reference_site\": \"631\", \"IC90\": 0.0895898412944801, \"functional effect\": -1.4315, \"times_seen\": 3.0}, {\"site\": 629, \"mutant\": \"A\", \"log2 fold change IC90\": 0.012100526723222092, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.0881804629044682, \"functional effect\": -0.2457, \"times_seen\": 23.0}, {\"site\": 629, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004875288890750164, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.08714894712627694, \"functional effect\": -0.5282, \"times_seen\": 20.0}, {\"site\": 629, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02097164987032181, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.08618201761013017, \"functional effect\": -0.2064, \"times_seen\": 46.0}, {\"site\": 629, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": null, \"functional effect\": -0.5555, \"times_seen\": null}, {\"site\": 629, \"mutant\": \"S\", \"log2 fold change IC90\": 0.019600947835454213, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.08864009769944711, \"functional effect\": 0.0444, \"times_seen\": 3.0}, {\"site\": 629, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"632\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 630, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0023486628754187046, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08730170686954432, \"functional effect\": -1.8527, \"times_seen\": 5.0}, {\"site\": 630, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006268893448330095, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08706480423670815, \"functional effect\": -3.0486, \"times_seen\": 1.0}, {\"site\": 630, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": null, \"functional effect\": -3.2461, \"times_seen\": null}, {\"site\": 630, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010061342922497905, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.0868362353058186, \"functional effect\": -3.1025, \"times_seen\": 1.0}, {\"site\": 630, \"mutant\": \"R\", \"log2 fold change IC90\": -0.009842595184695088, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.08684940279419058, \"functional effect\": -2.6673, \"times_seen\": 2.0}, {\"site\": 630, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 630, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"633\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 631, \"mutant\": \"G\", \"log2 fold change IC90\": -0.021882706689420682, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08612761115117204, \"functional effect\": -1.3895, \"times_seen\": 7.0}, {\"site\": 631, \"mutant\": \"H\", \"log2 fold change IC90\": -0.516433789732162, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.06113187147074987, \"functional effect\": -0.1903, \"times_seen\": 4.0}, {\"site\": 631, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03856746659282711, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08513728342556845, \"functional effect\": -0.1111, \"times_seen\": 10.0}, {\"site\": 631, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": null, \"functional effect\": -0.6942, \"times_seen\": null}, {\"site\": 631, \"mutant\": \"M\", \"log2 fold change IC90\": 0.010548995659030566, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08808568113703427, \"functional effect\": -0.2623, \"times_seen\": 4.0}, {\"site\": 631, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 631, \"mutant\": \"S\", \"log2 fold change IC90\": -0.010538686864992696, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.08680750858735277, \"functional effect\": -0.679, \"times_seen\": 2.0}, {\"site\": 631, \"mutant\": \"W\", \"log2 fold change IC90\": -0.014672261810355967, \"epitope\": \"all\", \"reference_site\": \"634\", \"IC90\": 0.0865591457842941, \"functional effect\": -2.2069, \"times_seen\": 1.0}, {\"site\": 632, \"mutant\": \"A\", \"log2 fold change IC90\": -0.023424803271057185, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08603559854131769, \"functional effect\": -0.3495, \"times_seen\": 8.0}, {\"site\": 632, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": null, \"functional effect\": -0.0971, \"times_seen\": null}, {\"site\": 632, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0006728878580538356, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08748474136847088, \"functional effect\": 0.0355, \"times_seen\": 33.0}, {\"site\": 632, \"mutant\": \"G\", \"log2 fold change IC90\": 0.025279018998872686, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08898964941145882, \"functional effect\": -0.5959, \"times_seen\": 15.0}, {\"site\": 632, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04009369246433855, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08504726438889738, \"functional effect\": 0.0208, \"times_seen\": 39.0}, {\"site\": 632, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0096640339163695, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.08803166517925923, \"functional effect\": 0.1798, \"times_seen\": 4.0}, {\"site\": 632, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"635\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 633, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": null, \"functional effect\": -2.9962, \"times_seen\": null}, {\"site\": 633, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": null, \"functional effect\": -3.0175, \"times_seen\": null}, {\"site\": 633, \"mutant\": \"F\", \"log2 fold change IC90\": -0.024871721013883092, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.0859493543760702, \"functional effect\": -0.1222, \"times_seen\": 7.0}, {\"site\": 633, \"mutant\": \"H\", \"log2 fold change IC90\": -0.043143414699502114, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.08486767232234087, \"functional effect\": -0.4859, \"times_seen\": 13.0}, {\"site\": 633, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00850182340703338, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.08796077692882409, \"functional effect\": -1.1597, \"times_seen\": 2.0}, {\"site\": 633, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0056200609329873, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.0871039692571361, \"functional effect\": -2.7835, \"times_seen\": 1.0}, {\"site\": 633, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"636\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"A\", \"log2 fold change IC90\": 0.028657968139988367, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.0891983171424248, \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 634, \"mutant\": \"C\", \"log2 fold change IC90\": -0.044125197363327213, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08480993783066483, \"functional effect\": -0.3422, \"times_seen\": 14.0}, {\"site\": 634, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": -2.2629, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"G\", \"log2 fold change IC90\": 0.002932221285656146, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08762185423458975, \"functional effect\": -1.0914, \"times_seen\": 6.0}, {\"site\": 634, \"mutant\": \"I\", \"log2 fold change IC90\": -0.008749165271309006, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08691525158985172, \"functional effect\": 0.0202, \"times_seen\": 4.0}, {\"site\": 634, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00999687912604147, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.08684011548721787, \"functional effect\": -2.5185, \"times_seen\": 2.0}, {\"site\": 634, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": -3.2586, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": -1.5063, \"times_seen\": null}, {\"site\": 634, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"637\", \"IC90\": null, \"functional effect\": 0.5058, \"times_seen\": null}, {\"site\": 635, \"mutant\": \"A\", \"log2 fold change IC90\": 0.005317357317441113, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08776683490441074, \"functional effect\": -0.1178, \"times_seen\": 4.0}, {\"site\": 635, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05117293051895432, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08439664173703093, \"functional effect\": -0.7965, \"times_seen\": 30.0}, {\"site\": 635, \"mutant\": \"K\", \"log2 fold change IC90\": -0.07557850528189221, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08298094105853666, \"functional effect\": 0.0897, \"times_seen\": 14.0}, {\"site\": 635, \"mutant\": \"R\", \"log2 fold change IC90\": -0.020832621658983773, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08619032311389821, \"functional effect\": -0.0527, \"times_seen\": 7.0}, {\"site\": 635, \"mutant\": \"S\", \"log2 fold change IC90\": 0.011941483641312447, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.08817074240277961, \"functional effect\": 0.1727, \"times_seen\": 5.0}, {\"site\": 635, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"638\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 636, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02087084023165055, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08618803986802687, \"functional effect\": -0.9815, \"times_seen\": 3.0}, {\"site\": 636, \"mutant\": \"C\", \"log2 fold change IC90\": -0.014140091849462194, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.0865910809284937, \"functional effect\": -2.863, \"times_seen\": 2.0}, {\"site\": 636, \"mutant\": \"D\", \"log2 fold change IC90\": -0.011791787260871529, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08673214179646437, \"functional effect\": -0.9954, \"times_seen\": 16.0}, {\"site\": 636, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 636, \"mutant\": \"R\", \"log2 fold change IC90\": -0.009833009152397518, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.08684997986967954, \"functional effect\": -2.3057, \"times_seen\": 1.0}, {\"site\": 636, \"mutant\": \"S\", \"log2 fold change IC90\": -1.5420913597835564, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.030027141979103358, \"functional effect\": -0.7301, \"times_seen\": 22.0}, {\"site\": 636, \"mutant\": \"V\", \"log2 fold change IC90\": -0.008185027300904982, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.0869492447623753, \"functional effect\": -2.3083, \"times_seen\": 3.0}, {\"site\": 636, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004092280088523935, \"epitope\": \"all\", \"reference_site\": \"639\", \"IC90\": 0.087196259213714, \"functional effect\": -2.4438, \"times_seen\": 1.0}, {\"site\": 637, \"mutant\": \"*\", \"log2 fold change IC90\": -0.003950252984784598, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08720484373186173, \"functional effect\": -2.6987, \"times_seen\": 1.0}, {\"site\": 637, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04250148224608179, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08490544290707887, \"functional effect\": -0.0979, \"times_seen\": 27.0}, {\"site\": 637, \"mutant\": \"C\", \"log2 fold change IC90\": -0.018219362392624738, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08634658744705649, \"functional effect\": -1.0014, \"times_seen\": 34.0}, {\"site\": 637, \"mutant\": \"D\", \"log2 fold change IC90\": -0.06058173870600336, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08384802399977545, \"functional effect\": 0.0859, \"times_seen\": 27.0}, {\"site\": 637, \"mutant\": \"E\", \"log2 fold change IC90\": -0.009571329907095862, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08686573434154603, \"functional effect\": -0.1585, \"times_seen\": 7.0}, {\"site\": 637, \"mutant\": \"F\", \"log2 fold change IC90\": -0.015194715207103998, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08652780518149393, \"functional effect\": -0.5928, \"times_seen\": 33.0}, {\"site\": 637, \"mutant\": \"G\", \"log2 fold change IC90\": 0.03980464662860477, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08989015833898041, \"functional effect\": -0.2261, \"times_seen\": 44.0}, {\"site\": 637, \"mutant\": \"H\", \"log2 fold change IC90\": 0.13797417491665173, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.09621972649861105, \"functional effect\": -0.0838, \"times_seen\": 16.0}, {\"site\": 637, \"mutant\": \"I\", \"log2 fold change IC90\": 1.0029080441027678, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.1752407716990596, \"functional effect\": -0.3659, \"times_seen\": 19.0}, {\"site\": 637, \"mutant\": \"K\", \"log2 fold change IC90\": -0.020510183743103517, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08620958853950951, \"functional effect\": 0.0309, \"times_seen\": 11.0}, {\"site\": 637, \"mutant\": \"L\", \"log2 fold change IC90\": -0.037772304295205096, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08518422100819438, \"functional effect\": -0.485, \"times_seen\": 22.0}, {\"site\": 637, \"mutant\": \"M\", \"log2 fold change IC90\": -0.012967494823227227, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.0866614892378116, \"functional effect\": -0.0281, \"times_seen\": 8.0}, {\"site\": 637, \"mutant\": \"N\", \"log2 fold change IC90\": -0.05116890454502782, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08439687725399299, \"functional effect\": -0.1217, \"times_seen\": 59.0}, {\"site\": 637, \"mutant\": \"P\", \"log2 fold change IC90\": -0.8240168021697766, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.049394202564687247, \"functional effect\": -0.7143, \"times_seen\": 41.0}, {\"site\": 637, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02220415097017978, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08880018453711061, \"functional effect\": 0.0478, \"times_seen\": 11.0}, {\"site\": 637, \"mutant\": \"R\", \"log2 fold change IC90\": -0.2489261080704135, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.07358605616440358, \"functional effect\": -0.2198, \"times_seen\": 43.0}, {\"site\": 637, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 637, \"mutant\": \"T\", \"log2 fold change IC90\": -0.33308439181008187, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.0694162837670795, \"functional effect\": -0.0095, \"times_seen\": 27.0}, {\"site\": 637, \"mutant\": \"V\", \"log2 fold change IC90\": -0.034255614159808594, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08539211796998877, \"functional effect\": -0.0794, \"times_seen\": 18.0}, {\"site\": 637, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 637, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06865795763999011, \"epitope\": \"all\", \"reference_site\": \"640\", \"IC90\": 0.08337995341236007, \"functional effect\": -0.3701, \"times_seen\": 11.0}, {\"site\": 638, \"mutant\": \"D\", \"log2 fold change IC90\": 0.002367806255894233, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08758758128199146, \"functional effect\": -0.2823, \"times_seen\": 8.0}, {\"site\": 638, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": null, \"functional effect\": -0.6966, \"times_seen\": null}, {\"site\": 638, \"mutant\": \"H\", \"log2 fold change IC90\": 0.030016230230927615, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08928233472015736, \"functional effect\": 0.0799, \"times_seen\": 6.0}, {\"site\": 638, \"mutant\": \"I\", \"log2 fold change IC90\": 0.006172980842849242, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08781890248590776, \"functional effect\": -0.6825, \"times_seen\": 1.0}, {\"site\": 638, \"mutant\": \"K\", \"log2 fold change IC90\": -0.007474688877047345, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.08699206642282085, \"functional effect\": -0.1028, \"times_seen\": 13.0}, {\"site\": 638, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 638, \"mutant\": \"R\", \"log2 fold change IC90\": -0.5420668329609745, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.060055304931625746, \"functional effect\": -0.0317, \"times_seen\": 5.0}, {\"site\": 638, \"mutant\": \"S\", \"log2 fold change IC90\": 0.14770924906023586, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.09687119727849032, \"functional effect\": -0.065, \"times_seen\": 29.0}, {\"site\": 638, \"mutant\": \"T\", \"log2 fold change IC90\": 1.1822688431478616, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.1984395061497003, \"functional effect\": -0.1098, \"times_seen\": 17.0}, {\"site\": 638, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.5014835399261589, \"epitope\": \"all\", \"reference_site\": \"641\", \"IC90\": 0.12379164687946762, \"functional effect\": 0.2456, \"times_seen\": 8.0}, {\"site\": 639, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0046670632851194055, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08772728296432954, \"functional effect\": -0.2545, \"times_seen\": 9.0}, {\"site\": 639, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0073797606069959205, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08699779062497792, \"functional effect\": -0.783, \"times_seen\": 2.0}, {\"site\": 639, \"mutant\": \"F\", \"log2 fold change IC90\": 0.13899236171063428, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.09628765785721566, \"functional effect\": -0.7632, \"times_seen\": 15.0}, {\"site\": 639, \"mutant\": \"G\", \"log2 fold change IC90\": 0.32540448103694203, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.10956863779367579, \"functional effect\": 0.0204, \"times_seen\": 16.0}, {\"site\": 639, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01640789674477013, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08645507337876113, \"functional effect\": -0.2273, \"times_seen\": 20.0}, {\"site\": 639, \"mutant\": \"L\", \"log2 fold change IC90\": 0.07491865399737345, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.09210485324556547, \"functional effect\": -0.605, \"times_seen\": 6.0}, {\"site\": 639, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0705269736165229, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.08327200435895513, \"functional effect\": 0.1893, \"times_seen\": 13.0}, {\"site\": 639, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": null, \"functional effect\": 0.2404, \"times_seen\": null}, {\"site\": 639, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"642\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 640, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 640, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": null, \"functional effect\": 0.0966, \"times_seen\": null}, {\"site\": 640, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0462258813692412, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.09029113860881544, \"functional effect\": -0.1246, \"times_seen\": 10.0}, {\"site\": 640, \"mutant\": \"L\", \"log2 fold change IC90\": 0.019293925505742188, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.08862123605997695, \"functional effect\": -0.0159, \"times_seen\": 14.0}, {\"site\": 640, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008310038515997755, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.08694171083489126, \"functional effect\": -2.1946, \"times_seen\": 1.0}, {\"site\": 640, \"mutant\": \"V\", \"log2 fold change IC90\": -0.007997615021186899, \"epitope\": \"all\", \"reference_site\": \"643\", \"IC90\": 0.08696054057623963, \"functional effect\": -0.1933, \"times_seen\": 3.0}, {\"site\": 641, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": null, \"functional effect\": -1.2621, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"H\", \"log2 fold change IC90\": -0.05706116272562253, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08405288628936541, \"functional effect\": -0.2035, \"times_seen\": 17.0}, {\"site\": 641, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004805323492837992, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.0871531736318404, \"functional effect\": -2.4358, \"times_seen\": 1.0}, {\"site\": 641, \"mutant\": \"L\", \"log2 fold change IC90\": -0.02374917448920147, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08601625673031064, \"functional effect\": -0.7004, \"times_seen\": 10.0}, {\"site\": 641, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": null, \"functional effect\": -2.1822, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 641, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03691998502090388, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08523456124104767, \"functional effect\": -2.2531, \"times_seen\": 10.0}, {\"site\": 641, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005548958269879259, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.0871082622481191, \"functional effect\": -0.2763, \"times_seen\": 1.0}, {\"site\": 641, \"mutant\": \"T\", \"log2 fold change IC90\": -0.014940105679531811, \"epitope\": \"all\", \"reference_site\": \"644\", \"IC90\": 0.08654307711846454, \"functional effect\": -0.0797, \"times_seen\": 2.0}, {\"site\": 642, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0035125687061321256, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.08723130391807768, \"functional effect\": -2.343, \"times_seen\": 1.0}, {\"site\": 642, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": null, \"functional effect\": -2.5747, \"times_seen\": null}, {\"site\": 642, \"mutant\": \"I\", \"log2 fold change IC90\": -0.022633424854850835, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.08608280560268392, \"functional effect\": -1.6248, \"times_seen\": 12.0}, {\"site\": 642, \"mutant\": \"N\", \"log2 fold change IC90\": -0.01027917630995024, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.08682312484049522, \"functional effect\": -2.5189, \"times_seen\": 2.0}, {\"site\": 642, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": null, \"functional effect\": -0.1741, \"times_seen\": null}, {\"site\": 642, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 642, \"mutant\": \"V\", \"log2 fold change IC90\": -0.062481694964103676, \"epitope\": \"all\", \"reference_site\": \"645\", \"IC90\": 0.08373767308052622, \"functional effect\": -2.6014, \"times_seen\": 4.0}, {\"site\": 643, \"mutant\": \"G\", \"log2 fold change IC90\": 0.01615811658277387, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.0884288201606388, \"functional effect\": 0.2698, \"times_seen\": 17.0}, {\"site\": 643, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0362144710937814, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08527625326484758, \"functional effect\": -0.115, \"times_seen\": 16.0}, {\"site\": 643, \"mutant\": \"K\", \"log2 fold change IC90\": 0.013277951708377119, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08825245889562125, \"functional effect\": -0.1284, \"times_seen\": 8.0}, {\"site\": 643, \"mutant\": \"L\", \"log2 fold change IC90\": 0.39861972331648177, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.11527264181053609, \"functional effect\": 0.2324, \"times_seen\": 19.0}, {\"site\": 643, \"mutant\": \"M\", \"log2 fold change IC90\": -0.001361560181872838, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08736145978705546, \"functional effect\": 0.0412, \"times_seen\": 11.0}, {\"site\": 643, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0021311072316860425, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08757321220618884, \"functional effect\": -0.2483, \"times_seen\": 1.0}, {\"site\": 643, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 643, \"mutant\": \"S\", \"log2 fold change IC90\": 2.2104972945330035, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.4047210040436252, \"functional effect\": 0.1537, \"times_seen\": 12.0}, {\"site\": 643, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004482812842211917, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.08717265867052466, \"functional effect\": 0.4244, \"times_seen\": 4.0}, {\"site\": 643, \"mutant\": \"W\", \"log2 fold change IC90\": 0.004257691332905363, \"epitope\": \"all\", \"reference_site\": \"646\", \"IC90\": 0.0877023934393127, \"functional effect\": -0.8314, \"times_seen\": 1.0}, {\"site\": 644, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 644, \"mutant\": \"C\", \"log2 fold change IC90\": 0.004943723680366681, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08774410772035099, \"functional effect\": -2.0077, \"times_seen\": 4.0}, {\"site\": 644, \"mutant\": \"D\", \"log2 fold change IC90\": 0.006131342184900739, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08781636791805376, \"functional effect\": -0.9453, \"times_seen\": 7.0}, {\"site\": 644, \"mutant\": \"S\", \"log2 fold change IC90\": -0.010238118076937839, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08682559580956081, \"functional effect\": -1.0248, \"times_seen\": 17.0}, {\"site\": 644, \"mutant\": \"T\", \"log2 fold change IC90\": -0.052402039427375584, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.08432477035319001, \"functional effect\": -1.1521, \"times_seen\": 23.0}, {\"site\": 644, \"mutant\": \"V\", \"log2 fold change IC90\": -1.9132083944115745, \"epitope\": \"all\", \"reference_site\": \"647\", \"IC90\": 0.023216494109599275, \"functional effect\": -0.6934, \"times_seen\": 34.0}, {\"site\": 645, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -3.2615, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"C\", \"log2 fold change IC90\": -0.003980146700751975, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.08720303680125784, \"functional effect\": -3.0583, \"times_seen\": 1.0}, {\"site\": 645, \"mutant\": \"D\", \"log2 fold change IC90\": 0.03998569489131353, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.08990143964081435, \"functional effect\": -2.6399, \"times_seen\": 7.0}, {\"site\": 645, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -3.1376, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -2.739, \"times_seen\": null}, {\"site\": 645, \"mutant\": \"S\", \"log2 fold change IC90\": -0.003801404247561348, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": 0.08721384147576548, \"functional effect\": -2.8237, \"times_seen\": 1.0}, {\"site\": 645, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"648\", \"IC90\": null, \"functional effect\": -2.6423, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -3.1327, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.2135, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0013190904469904475, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": 0.08752393574259, \"functional effect\": -2.3547, \"times_seen\": 3.0}, {\"site\": 646, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.922, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.479, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.7214, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 646, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"649\", \"IC90\": null, \"functional effect\": -2.8815, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.1532, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.8995, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.5692, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"M\", \"log2 fold change IC90\": 0.04824031153851622, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": 0.09041729987674368, \"functional effect\": -1.8481, \"times_seen\": 2.0}, {\"site\": 647, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0020185482644267875, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": 0.08732168535817499, \"functional effect\": -2.4623, \"times_seen\": 2.0}, {\"site\": 647, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -1.9246, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.9784, \"times_seen\": null}, {\"site\": 647, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"650\", \"IC90\": null, \"functional effect\": -2.8907, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": null, \"functional effect\": -1.796, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": null, \"functional effect\": -2.8124, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"M\", \"log2 fold change IC90\": 0.019821089066902383, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.08865362434822517, \"functional effect\": -1.436, \"times_seen\": 5.0}, {\"site\": 648, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": null, \"functional effect\": -2.9986, \"times_seen\": null}, {\"site\": 648, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00254673541154769, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.08728972174239787, \"functional effect\": -1.2201, \"times_seen\": 1.0}, {\"site\": 648, \"mutant\": \"V\", \"log2 fold change IC90\": 0.01663824454266926, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.08845825411130445, \"functional effect\": 0.0312, \"times_seen\": 16.0}, {\"site\": 648, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010272709585985427, \"epitope\": \"all\", \"reference_site\": \"651\", \"IC90\": 0.0868235140166028, \"functional effect\": -2.371, \"times_seen\": 4.0}, {\"site\": 649, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.9974, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.918, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.6322, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"R\", \"log2 fold change IC90\": 0.06178790713082716, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": 0.09127036056891843, \"functional effect\": -1.3668, \"times_seen\": 5.0}, {\"site\": 649, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": null, \"functional effect\": -2.8331, \"times_seen\": null}, {\"site\": 649, \"mutant\": \"V\", \"log2 fold change IC90\": 0.02794652979716968, \"epitope\": \"all\", \"reference_site\": \"652\", \"IC90\": 0.08915434148792897, \"functional effect\": -1.6485, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"*\", \"log2 fold change IC90\": -0.024719316734568886, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08595843442483095, \"functional effect\": -2.8739, \"times_seen\": 4.0}, {\"site\": 650, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 650, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 650, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03907994882105418, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.0851070458528932, \"functional effect\": -1.62, \"times_seen\": 9.0}, {\"site\": 650, \"mutant\": \"D\", \"log2 fold change IC90\": -0.012756412529316804, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08667416970298387, \"functional effect\": -1.2756, \"times_seen\": 2.0}, {\"site\": 650, \"mutant\": \"E\", \"log2 fold change IC90\": -0.029360001674421658, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08568237807741903, \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"F\", \"log2 fold change IC90\": -0.018552172310756215, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08632667077338387, \"functional effect\": -2.7272, \"times_seen\": 2.0}, {\"site\": 650, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0020822930499547645, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08731782717680125, \"functional effect\": -2.3114, \"times_seen\": 7.0}, {\"site\": 650, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": null, \"functional effect\": -2.8205, \"times_seen\": null}, {\"site\": 650, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05133212801339359, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.0843873293097669, \"functional effect\": -1.9183, \"times_seen\": 4.0}, {\"site\": 650, \"mutant\": \"K\", \"log2 fold change IC90\": -0.015114498240324875, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08653261644849619, \"functional effect\": -3.1279, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"L\", \"log2 fold change IC90\": -0.036637709299422734, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08525123974931151, \"functional effect\": -2.5903, \"times_seen\": 8.0}, {\"site\": 650, \"mutant\": \"M\", \"log2 fold change IC90\": -6.130775146237513, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.0012479079088180338, \"functional effect\": -2.4428, \"times_seen\": 5.0}, {\"site\": 650, \"mutant\": \"N\", \"log2 fold change IC90\": -0.009847964151390115, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08684907958611804, \"functional effect\": -1.5743, \"times_seen\": 1.0}, {\"site\": 650, \"mutant\": \"P\", \"log2 fold change IC90\": -0.028184910120295285, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08575219578073784, \"functional effect\": -2.9389, \"times_seen\": 7.0}, {\"site\": 650, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.012106219379893425, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08818081085193911, \"functional effect\": -3.0575, \"times_seen\": 2.0}, {\"site\": 650, \"mutant\": \"R\", \"log2 fold change IC90\": -4.557043536690337, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.0037146932508467802, \"functional effect\": -2.5286, \"times_seen\": 11.0}, {\"site\": 650, \"mutant\": \"S\", \"log2 fold change IC90\": -0.006987792118787388, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08702143042709902, \"functional effect\": -2.3997, \"times_seen\": 9.0}, {\"site\": 650, \"mutant\": \"T\", \"log2 fold change IC90\": -0.10536820300004714, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.08128506608136135, \"functional effect\": -2.2728, \"times_seen\": 27.0}, {\"site\": 650, \"mutant\": \"V\", \"log2 fold change IC90\": 0.046687146975530454, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.09032001155445253, \"functional effect\": -0.1762, \"times_seen\": 97.0}, {\"site\": 650, \"mutant\": \"W\", \"log2 fold change IC90\": -0.3026168694436489, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": 0.07089783900745983, \"functional effect\": -2.8587, \"times_seen\": 3.0}, {\"site\": 650, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"653\", \"IC90\": null, \"functional effect\": -2.7765, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"*\", \"log2 fold change IC90\": 0.04974461379003293, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.09051162742356718, \"functional effect\": -0.7878, \"times_seen\": 4.0}, {\"site\": 651, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": null, \"functional effect\": 0.1923, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03559169786950694, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08531307271036574, \"functional effect\": -0.375, \"times_seen\": 7.0}, {\"site\": 651, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 651, \"mutant\": \"G\", \"log2 fold change IC90\": -0.019663245020899323, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08626021301142121, \"functional effect\": -1.1807, \"times_seen\": 4.0}, {\"site\": 651, \"mutant\": \"K\", \"log2 fold change IC90\": -0.003450233215390591, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08723507306086842, \"functional effect\": -0.0612, \"times_seen\": 49.0}, {\"site\": 651, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05301997168972852, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08428866026959579, \"functional effect\": -0.0988, \"times_seen\": 16.0}, {\"site\": 651, \"mutant\": \"R\", \"log2 fold change IC90\": 0.009393193808687637, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08801514036483926, \"functional effect\": -0.0751, \"times_seen\": 7.0}, {\"site\": 651, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0015500014467010959, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08753794553425936, \"functional effect\": 0.1148, \"times_seen\": 5.0}, {\"site\": 651, \"mutant\": \"V\", \"log2 fold change IC90\": 0.000165123793287921, \"epitope\": \"all\", \"reference_site\": \"654\", \"IC90\": 0.08745395607405185, \"functional effect\": -0.0384, \"times_seen\": 26.0}, {\"site\": 652, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0055986355399369175, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08778394822728257, \"functional effect\": -2.7181, \"times_seen\": 6.0}, {\"site\": 652, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 652, \"mutant\": \"A\", \"log2 fold change IC90\": -0.056392007181052334, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08409188101733207, \"functional effect\": -1.7225, \"times_seen\": 23.0}, {\"site\": 652, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0022491430547025245, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08730772931340282, \"functional effect\": -1.9318, \"times_seen\": 1.0}, {\"site\": 652, \"mutant\": \"D\", \"log2 fold change IC90\": -0.020021353238196492, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08623880401180462, \"functional effect\": -1.3138, \"times_seen\": 3.0}, {\"site\": 652, \"mutant\": \"E\", \"log2 fold change IC90\": 0.026719616247857524, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.089078554043222, \"functional effect\": -2.9528, \"times_seen\": 1.0}, {\"site\": 652, \"mutant\": \"F\", \"log2 fold change IC90\": -0.00412767490858404, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08719411998265109, \"functional effect\": -0.1608, \"times_seen\": 15.0}, {\"site\": 652, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0474385583907308, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.09036706596502096, \"functional effect\": -2.9483, \"times_seen\": 5.0}, {\"site\": 652, \"mutant\": \"H\", \"log2 fold change IC90\": -0.012638241912439343, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08668126944291189, \"functional effect\": -0.9786, \"times_seen\": 25.0}, {\"site\": 652, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0306969871123393, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08560301062707582, \"functional effect\": -1.8491, \"times_seen\": 7.0}, {\"site\": 652, \"mutant\": \"K\", \"log2 fold change IC90\": 0.009784985632001805, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.0880390458293457, \"functional effect\": -1.7056, \"times_seen\": 7.0}, {\"site\": 652, \"mutant\": \"L\", \"log2 fold change IC90\": -0.09530617139572625, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08185396782933617, \"functional effect\": -1.0489, \"times_seen\": 17.0}, {\"site\": 652, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06356900495820571, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08367458663143452, \"functional effect\": -1.0462, \"times_seen\": 16.0}, {\"site\": 652, \"mutant\": \"N\", \"log2 fold change IC90\": -0.2556735069721823, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.07324270210538959, \"functional effect\": -1.8558, \"times_seen\": 6.0}, {\"site\": 652, \"mutant\": \"P\", \"log2 fold change IC90\": -0.2057648264125319, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.07582080097432543, \"functional effect\": -1.6151, \"times_seen\": 12.0}, {\"site\": 652, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01845370533340642, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08633256295169182, \"functional effect\": -2.7885, \"times_seen\": 5.0}, {\"site\": 652, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03412491078354837, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08539985456254652, \"functional effect\": -1.6506, \"times_seen\": 25.0}, {\"site\": 652, \"mutant\": \"S\", \"log2 fold change IC90\": -0.036108342289263545, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08528252666251394, \"functional effect\": -2.3491, \"times_seen\": 12.0}, {\"site\": 652, \"mutant\": \"T\", \"log2 fold change IC90\": 0.03124497136600886, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08935840873801926, \"functional effect\": -2.4896, \"times_seen\": 5.0}, {\"site\": 652, \"mutant\": \"V\", \"log2 fold change IC90\": -0.13902917334358617, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.07941047638591528, \"functional effect\": -1.3823, \"times_seen\": 18.0}, {\"site\": 652, \"mutant\": \"W\", \"log2 fold change IC90\": 0.03426004832812888, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.08954535344919885, \"functional effect\": -0.2047, \"times_seen\": 17.0}, {\"site\": 652, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"655\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 653, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 653, \"mutant\": \"A\", \"log2 fold change IC90\": 0.013139012991430367, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08824396015358138, \"functional effect\": -1.2286, \"times_seen\": 7.0}, {\"site\": 653, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02809922105699511, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08575728919504018, \"functional effect\": -0.6411, \"times_seen\": 10.0}, {\"site\": 653, \"mutant\": \"L\", \"log2 fold change IC90\": 0.030366680204941616, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08930402523101466, \"functional effect\": -0.8782, \"times_seen\": 9.0}, {\"site\": 653, \"mutant\": \"M\", \"log2 fold change IC90\": 0.006704614795124033, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08785126976529355, \"functional effect\": -1.2335, \"times_seen\": 19.0}, {\"site\": 653, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0288727277425402, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.08921159619341014, \"functional effect\": -0.3178, \"times_seen\": 6.0}, {\"site\": 653, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"656\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"D\", \"log2 fold change IC90\": -0.049673886100698894, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08448438035245573, \"functional effect\": 0.0139, \"times_seen\": 40.0}, {\"site\": 654, \"mutant\": \"H\", \"log2 fold change IC90\": -0.026735408873527423, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08583839582596414, \"functional effect\": 0.0081, \"times_seen\": 8.0}, {\"site\": 654, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": null, \"functional effect\": -0.8364, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"K\", \"log2 fold change IC90\": 0.009772619693169157, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.0880382912133257, \"functional effect\": -0.2966, \"times_seen\": 12.0}, {\"site\": 654, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 654, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00970615368747288, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08685761688142078, \"functional effect\": -0.2064, \"times_seen\": 11.0}, {\"site\": 654, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06143719945716719, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.08379832019569054, \"functional effect\": -0.0316, \"times_seen\": 13.0}, {\"site\": 654, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.605162793446583, \"epitope\": \"all\", \"reference_site\": \"657\", \"IC90\": 0.057485405570286155, \"functional effect\": -0.6074, \"times_seen\": 36.0}, {\"site\": 655, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 655, \"mutant\": \"D\", \"log2 fold change IC90\": 0.01668545602240907, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08846114891116648, \"functional effect\": 0.3327, \"times_seen\": 29.0}, {\"site\": 655, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": null, \"functional effect\": -0.4271, \"times_seen\": null}, {\"site\": 655, \"mutant\": \"H\", \"log2 fold change IC90\": -0.015593678910261788, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08650388004156355, \"functional effect\": 0.1507, \"times_seen\": 8.0}, {\"site\": 655, \"mutant\": \"I\", \"log2 fold change IC90\": 0.016400910129012743, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08844370324606977, \"functional effect\": 0.1099, \"times_seen\": 3.0}, {\"site\": 655, \"mutant\": \"K\", \"log2 fold change IC90\": -0.05428927894537907, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08421453430824592, \"functional effect\": -0.0312, \"times_seen\": 23.0}, {\"site\": 655, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 655, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01606433605311051, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08647566407943096, \"functional effect\": 0.1005, \"times_seen\": 9.0}, {\"site\": 655, \"mutant\": \"T\", \"log2 fold change IC90\": 1.0766811605000361, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.18443488866647326, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 655, \"mutant\": \"V\", \"log2 fold change IC90\": 0.016993361699704106, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08848003065401042, \"functional effect\": 0.0244, \"times_seen\": 1.0}, {\"site\": 655, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0002176215019960512, \"epitope\": \"all\", \"reference_site\": \"658\", \"IC90\": 0.08745713846237008, \"functional effect\": -0.0921, \"times_seen\": 12.0}, {\"site\": 656, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 656, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004479825736864906, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08717283916201941, \"functional effect\": -0.6133, \"times_seen\": 5.0}, {\"site\": 656, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005102833858277397, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08713520289064504, \"functional effect\": -1.035, \"times_seen\": 1.0}, {\"site\": 656, \"mutant\": \"F\", \"log2 fold change IC90\": -0.029688011587310353, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08566289961947185, \"functional effect\": -0.6814, \"times_seen\": 3.0}, {\"site\": 656, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04049170845628059, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08502380447435329, \"functional effect\": -0.324, \"times_seen\": 20.0}, {\"site\": 656, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03937844000868065, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08508943916910938, \"functional effect\": -0.881, \"times_seen\": 13.0}, {\"site\": 656, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 656, \"mutant\": \"T\", \"log2 fold change IC90\": 0.028509751753224268, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08918915375528896, \"functional effect\": -0.081, \"times_seen\": 15.0}, {\"site\": 656, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.042910207192133745, \"epitope\": \"all\", \"reference_site\": \"659\", \"IC90\": 0.08488139204652768, \"functional effect\": -0.666, \"times_seen\": 9.0}, {\"site\": 657, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": null, \"functional effect\": -1.5896, \"times_seen\": null}, {\"site\": 657, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 657, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": null, \"functional effect\": -0.4082, \"times_seen\": null}, {\"site\": 657, \"mutant\": \"F\", \"log2 fold change IC90\": 0.11830292968817396, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.0949166678038661, \"functional effect\": -0.0655, \"times_seen\": 17.0}, {\"site\": 657, \"mutant\": \"H\", \"log2 fold change IC90\": -0.1968214235174991, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.07629228114994582, \"functional effect\": -0.7964, \"times_seen\": 46.0}, {\"site\": 657, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009304041881985971, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.08688182944194572, \"functional effect\": -0.0063, \"times_seen\": 7.0}, {\"site\": 657, \"mutant\": \"N\", \"log2 fold change IC90\": 0.021118713061668588, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.08873339922652891, \"functional effect\": -1.6674, \"times_seen\": 6.0}, {\"site\": 657, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"660\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": null, \"functional effect\": -3.087, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"A\", \"log2 fold change IC90\": -0.022407973805377623, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08609625887922732, \"functional effect\": -0.4833, \"times_seen\": 7.0}, {\"site\": 658, \"mutant\": \"D\", \"log2 fold change IC90\": 1.1663252265532693, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.19625857027031432, \"functional effect\": -0.2119, \"times_seen\": 32.0}, {\"site\": 658, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 658, \"mutant\": \"G\", \"log2 fold change IC90\": -0.007706873300603569, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08697806722203194, \"functional effect\": -0.8207, \"times_seen\": 8.0}, {\"site\": 658, \"mutant\": \"K\", \"log2 fold change IC90\": 0.022106476029854258, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08879417269200604, \"functional effect\": -0.2801, \"times_seen\": 10.0}, {\"site\": 658, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.048884684997904895, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.09045769339023318, \"functional effect\": -0.1412, \"times_seen\": 5.0}, {\"site\": 658, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02421211158695239, \"epitope\": \"all\", \"reference_site\": \"661\", \"IC90\": 0.08598865995691432, \"functional effect\": -0.2856, \"times_seen\": 10.0}, {\"site\": 659, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": null, \"functional effect\": -3.1855, \"times_seen\": null}, {\"site\": 659, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 659, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 659, \"mutant\": \"F\", \"log2 fold change IC90\": -0.015183188322139702, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08652849652652028, \"functional effect\": -2.6796, \"times_seen\": 1.0}, {\"site\": 659, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011926802115298122, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08672402533440075, \"functional effect\": -2.0399, \"times_seen\": 2.0}, {\"site\": 659, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0213398616182115, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08616002461699568, \"functional effect\": -1.9582, \"times_seen\": 1.0}, {\"site\": 659, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007819935687010242, \"epitope\": \"all\", \"reference_site\": \"662\", \"IC90\": 0.08697125111589807, \"functional effect\": -2.0971, \"times_seen\": 2.0}, {\"site\": 660, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01800617929692897, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08635934758858517, \"functional effect\": -2.0284, \"times_seen\": 4.0}, {\"site\": 660, \"mutant\": \"G\", \"log2 fold change IC90\": -0.009106590677787676, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08689372114140294, \"functional effect\": -2.1022, \"times_seen\": 3.0}, {\"site\": 660, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": null, \"functional effect\": -1.7556, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0010954833347606968, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08737757338333323, \"functional effect\": -2.0753, \"times_seen\": 1.0}, {\"site\": 660, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": null, \"functional effect\": -3.125, \"times_seen\": null}, {\"site\": 660, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009970490762786003, \"epitope\": \"all\", \"reference_site\": \"663\", \"IC90\": 0.08684170389599823, \"functional effect\": -2.3828, \"times_seen\": 3.0}, {\"site\": 661, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": null, \"functional effect\": -2.3552, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0037745635301516937, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.08721546406666834, \"functional effect\": -2.5567, \"times_seen\": 1.0}, {\"site\": 661, \"mutant\": \"L\", \"log2 fold change IC90\": 0.002066715202146705, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.08756930362477298, \"functional effect\": -2.9382, \"times_seen\": 1.0}, {\"site\": 661, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": null, \"functional effect\": -2.2529, \"times_seen\": null}, {\"site\": 661, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003935510425239721, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.08720573486209622, \"functional effect\": -2.7824, \"times_seen\": 2.0}, {\"site\": 661, \"mutant\": \"V\", \"log2 fold change IC90\": 0.045866326254473226, \"epitope\": \"all\", \"reference_site\": \"664\", \"IC90\": 0.09026863863853252, \"functional effect\": -1.5756, \"times_seen\": 3.0}, {\"site\": 662, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": null, \"functional effect\": -1.4388, \"times_seen\": null}, {\"site\": 662, \"mutant\": \"A\", \"log2 fold change IC90\": 0.009971795664044728, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.0880504464659043, \"functional effect\": -0.2973, \"times_seen\": 2.0}, {\"site\": 662, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01038314306182198, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.0868168682216138, \"functional effect\": -2.3295, \"times_seen\": 2.0}, {\"site\": 662, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 662, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013721650854849797, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.08661619955168016, \"functional effect\": -1.8667, \"times_seen\": 3.0}, {\"site\": 662, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": null, \"functional effect\": -2.1018, \"times_seen\": null}, {\"site\": 662, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02928816550637566, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": 0.08568664456949023, \"functional effect\": -2.6498, \"times_seen\": 5.0}, {\"site\": 662, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"665\", \"IC90\": null, \"functional effect\": -1.5219, \"times_seen\": null}, {\"site\": 663, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0018769661434024174, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.08755778691486521, \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 663, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 663, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01847555243060618, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.0885709796542689, \"functional effect\": -0.8916, \"times_seen\": 3.0}, {\"site\": 663, \"mutant\": \"N\", \"log2 fold change IC90\": 0.4826057788357473, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.12218237656769772, \"functional effect\": -2.9339, \"times_seen\": 5.0}, {\"site\": 663, \"mutant\": \"S\", \"log2 fold change IC90\": 0.003316674898080931, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.08764520707512469, \"functional effect\": -2.7603, \"times_seen\": 1.0}, {\"site\": 663, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": null, \"functional effect\": -2.7785, \"times_seen\": null}, {\"site\": 663, \"mutant\": \"V\", \"log2 fold change IC90\": 0.34807659429035603, \"epitope\": \"all\", \"reference_site\": \"666\", \"IC90\": 0.1113041220879292, \"functional effect\": -0.2891, \"times_seen\": 24.0}, {\"site\": 664, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": null, \"functional effect\": -1.7201, \"times_seen\": null}, {\"site\": 664, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004788723087022574, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08715417646773649, \"functional effect\": -0.0997, \"times_seen\": 1.0}, {\"site\": 664, \"mutant\": \"E\", \"log2 fold change IC90\": 0.011190224152495246, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08812484090487122, \"functional effect\": -2.4207, \"times_seen\": 6.0}, {\"site\": 664, \"mutant\": \"F\", \"log2 fold change IC90\": -0.022697519361231315, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.086078981293168, \"functional effect\": -1.6171, \"times_seen\": 4.0}, {\"site\": 664, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 664, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005903153488790204, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08708687897441261, \"functional effect\": -2.2662, \"times_seen\": 1.0}, {\"site\": 664, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00912506578172412, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.0868926083904716, \"functional effect\": -0.9965, \"times_seen\": 3.0}, {\"site\": 664, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01873567955700832, \"epitope\": \"all\", \"reference_site\": \"667\", \"IC90\": 0.08631569093237712, \"functional effect\": -2.5453, \"times_seen\": 3.0}, {\"site\": 665, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 665, \"mutant\": \"E\", \"log2 fold change IC90\": -0.016305248437740366, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.08646122490932254, \"functional effect\": -0.4449, \"times_seen\": 8.0}, {\"site\": 665, \"mutant\": \"G\", \"log2 fold change IC90\": 0.00812956187491093, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.08793808315885342, \"functional effect\": 0.3625, \"times_seen\": 4.0}, {\"site\": 665, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0016645131409614294, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.0875448939994624, \"functional effect\": -0.0976, \"times_seen\": 23.0}, {\"site\": 665, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04329981129131768, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.0848584726682767, \"functional effect\": -1.6351, \"times_seen\": 10.0}, {\"site\": 665, \"mutant\": \"V\", \"log2 fold change IC90\": -0.47737065347957786, \"epitope\": \"all\", \"reference_site\": \"668\", \"IC90\": 0.06280972140479987, \"functional effect\": -0.9117, \"times_seen\": 45.0}, {\"site\": 666, \"mutant\": \"C\", \"log2 fold change IC90\": -0.015464917429551583, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08651160091425926, \"functional effect\": -2.698, \"times_seen\": 1.0}, {\"site\": 666, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004192315893253908, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08719021327517258, \"functional effect\": -2.4976, \"times_seen\": 1.0}, {\"site\": 666, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 666, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": null, \"functional effect\": -0.7519, \"times_seen\": null}, {\"site\": 666, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": null, \"functional effect\": -3.2764, \"times_seen\": null}, {\"site\": 666, \"mutant\": \"S\", \"log2 fold change IC90\": 0.016140501815280223, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08842774048437073, \"functional effect\": -1.2803, \"times_seen\": 8.0}, {\"site\": 666, \"mutant\": \"V\", \"log2 fold change IC90\": 0.031178987828973083, \"epitope\": \"all\", \"reference_site\": \"669\", \"IC90\": 0.08935432190825097, \"functional effect\": -1.3729, \"times_seen\": 1.0}, {\"site\": 667, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 667, \"mutant\": \"L\", \"log2 fold change IC90\": -0.13281469069422577, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.07975327886250957, \"functional effect\": 0.1047, \"times_seen\": 1.0}, {\"site\": 667, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0368663783339955, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.08970726963726186, \"functional effect\": -0.9151, \"times_seen\": 13.0}, {\"site\": 667, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0007600741972057945, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.08749002849055523, \"functional effect\": -2.6483, \"times_seen\": 1.0}, {\"site\": 667, \"mutant\": \"V\", \"log2 fold change IC90\": 0.5616835203691093, \"epitope\": \"all\", \"reference_site\": \"670\", \"IC90\": 0.12906644276864065, \"functional effect\": -0.2114, \"times_seen\": 10.0}, {\"site\": 668, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": null, \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 668, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 668, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": null, \"functional effect\": -2.9839, \"times_seen\": null}, {\"site\": 668, \"mutant\": \"G\", \"log2 fold change IC90\": -0.011417024010381072, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08675467479238304, \"functional effect\": -2.8933, \"times_seen\": 1.0}, {\"site\": 668, \"mutant\": \"R\", \"log2 fold change IC90\": -0.04643756555217377, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08467411236818394, \"functional effect\": -2.7944, \"times_seen\": 11.0}, {\"site\": 668, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0048356444592613165, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08715134196221695, \"functional effect\": -2.6835, \"times_seen\": 1.0}, {\"site\": 668, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.003671803498075254, \"epitope\": \"all\", \"reference_site\": \"671\", \"IC90\": 0.08722167645585656, \"functional effect\": -2.6498, \"times_seen\": 1.0}, {\"site\": 669, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 669, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": null, \"functional effect\": -2.9993, \"times_seen\": null}, {\"site\": 669, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": null, \"functional effect\": -2.7085, \"times_seen\": null}, {\"site\": 669, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0461906257958267, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.0902889321640154, \"functional effect\": -2.7888, \"times_seen\": 5.0}, {\"site\": 669, \"mutant\": \"T\", \"log2 fold change IC90\": -0.022067977301610517, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.08611655137052256, \"functional effect\": -1.3255, \"times_seen\": 19.0}, {\"site\": 669, \"mutant\": \"V\", \"log2 fold change IC90\": 0.013586659786220092, \"epitope\": \"all\", \"reference_site\": \"672\", \"IC90\": 0.08827134518915526, \"functional effect\": -0.208, \"times_seen\": 58.0}, {\"site\": 670, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004601018731032591, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08716551655165618, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 670, \"mutant\": \"C\", \"log2 fold change IC90\": -0.002092565284419364, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.0873172054612099, \"functional effect\": -1.6065, \"times_seen\": 1.0}, {\"site\": 670, \"mutant\": \"F\", \"log2 fold change IC90\": -0.9160521868596545, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.04634155120663201, \"functional effect\": -2.2149, \"times_seen\": 3.0}, {\"site\": 670, \"mutant\": \"G\", \"log2 fold change IC90\": 0.026412363344025868, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.089059584871392, \"functional effect\": -0.631, \"times_seen\": 5.0}, {\"site\": 670, \"mutant\": \"I\", \"log2 fold change IC90\": -0.026451253706576455, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08585530433763638, \"functional effect\": -2.7388, \"times_seen\": 6.0}, {\"site\": 670, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009249726275424155, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08688510049228247, \"functional effect\": -1.4861, \"times_seen\": 3.0}, {\"site\": 670, \"mutant\": \"P\", \"log2 fold change IC90\": -0.019316718720873642, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08628093466205543, \"functional effect\": -2.4918, \"times_seen\": 4.0}, {\"site\": 670, \"mutant\": \"R\", \"log2 fold change IC90\": -0.009640503136443787, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08686156947014644, \"functional effect\": 0.2607, \"times_seen\": 6.0}, {\"site\": 670, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 670, \"mutant\": \"T\", \"log2 fold change IC90\": -0.09447920959621449, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": 0.08190090048420552, \"functional effect\": 0.2622, \"times_seen\": 56.0}, {\"site\": 670, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"673\", \"IC90\": null, \"functional effect\": -2.1489, \"times_seen\": null}, {\"site\": 671, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": null, \"functional effect\": -2.2944, \"times_seen\": null}, {\"site\": 671, \"mutant\": \"C\", \"log2 fold change IC90\": -0.07552314954714938, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.08298412507106728, \"functional effect\": -2.3616, \"times_seen\": 2.0}, {\"site\": 671, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03315890214364131, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.08545705627226681, \"functional effect\": -0.2806, \"times_seen\": 21.0}, {\"site\": 671, \"mutant\": \"H\", \"log2 fold change IC90\": -1.0853686751468197, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.0412098681726371, \"functional effect\": -1.0209, \"times_seen\": 30.0}, {\"site\": 671, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": null, \"functional effect\": -3.0437, \"times_seen\": null}, {\"site\": 671, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"674\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": null, \"functional effect\": -1.5438, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004084191225775401, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.0871967481046648, \"functional effect\": 0.3023, \"times_seen\": 1.0}, {\"site\": 672, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": null, \"functional effect\": -0.3102, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"H\", \"log2 fold change IC90\": 0.024016802204089388, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08891182623688197, \"functional effect\": -0.1829, \"times_seen\": 46.0}, {\"site\": 672, \"mutant\": \"K\", \"log2 fold change IC90\": 0.007031654137493189, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08787118671056975, \"functional effect\": 0.0557, \"times_seen\": 36.0}, {\"site\": 672, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01937945222644224, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08627718294207196, \"functional effect\": 0.0046, \"times_seen\": 72.0}, {\"site\": 672, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": null, \"functional effect\": -3.2213, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"N\", \"log2 fold change IC90\": 0.04916403308988926, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.09047521034975911, \"functional effect\": 0.2948, \"times_seen\": 9.0}, {\"site\": 672, \"mutant\": \"P\", \"log2 fold change IC90\": 0.05615508200859997, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.0909147014512574, \"functional effect\": -0.4375, \"times_seen\": 6.0}, {\"site\": 672, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 672, \"mutant\": \"R\", \"log2 fold change IC90\": -0.06252477193271429, \"epitope\": \"all\", \"reference_site\": \"675\", \"IC90\": 0.08373517282152448, \"functional effect\": 0.1768, \"times_seen\": 38.0}, {\"site\": 673, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004980141581791124, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08714261351500326, \"functional effect\": -0.1647, \"times_seen\": 1.0}, {\"site\": 673, \"mutant\": \"A\", \"log2 fold change IC90\": -0.13037820946834888, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.07988808319677893, \"functional effect\": -0.1562, \"times_seen\": 26.0}, {\"site\": 673, \"mutant\": \"I\", \"log2 fold change IC90\": -0.036872306900071164, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08523737811554025, \"functional effect\": 0.1508, \"times_seen\": 34.0}, {\"site\": 673, \"mutant\": \"N\", \"log2 fold change IC90\": 0.006554281477072931, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.08784211586621955, \"functional effect\": 0.0301, \"times_seen\": 16.0}, {\"site\": 673, \"mutant\": \"P\", \"log2 fold change IC90\": -0.5284578109884488, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.06062449029658833, \"functional effect\": 0.2261, \"times_seen\": 10.0}, {\"site\": 673, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011379847966459147, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.0867569103564237, \"functional effect\": -0.4989, \"times_seen\": 1.0}, {\"site\": 673, \"mutant\": \"S\", \"log2 fold change IC90\": 0.5391881594546242, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.12706957053916001, \"functional effect\": 0.1098, \"times_seen\": 20.0}, {\"site\": 673, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"676\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 674, \"mutant\": \"*\", \"log2 fold change IC90\": -0.025954277944228464, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08588488463980691, \"functional effect\": -2.6388, \"times_seen\": 5.0}, {\"site\": 674, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": null, \"functional effect\": -0.2997, \"times_seen\": null}, {\"site\": 674, \"mutant\": \"A\", \"log2 fold change IC90\": -0.16507372969445588, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.07798976445575626, \"functional effect\": 0.0194, \"times_seen\": 59.0}, {\"site\": 674, \"mutant\": \"C\", \"log2 fold change IC90\": 0.050987109216482224, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.09058961252855437, \"functional effect\": -0.3555, \"times_seen\": 12.0}, {\"site\": 674, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03687896443306318, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08523698477576189, \"functional effect\": -0.0551, \"times_seen\": 21.0}, {\"site\": 674, \"mutant\": \"E\", \"log2 fold change IC90\": -0.026300968819182844, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08586424831154577, \"functional effect\": 0.0269, \"times_seen\": 60.0}, {\"site\": 674, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0015546726592522977, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08734976676920357, \"functional effect\": 0.0515, \"times_seen\": 12.0}, {\"site\": 674, \"mutant\": \"G\", \"log2 fold change IC90\": 0.00017487558767247238, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.0874545472148376, \"functional effect\": -0.0279, \"times_seen\": 73.0}, {\"site\": 674, \"mutant\": \"H\", \"log2 fold change IC90\": 0.029476535247477332, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08924894151150385, \"functional effect\": 0.0435, \"times_seen\": 82.0}, {\"site\": 674, \"mutant\": \"I\", \"log2 fold change IC90\": 0.028976957605475088, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08921804166392268, \"functional effect\": 0.4132, \"times_seen\": 18.0}, {\"site\": 674, \"mutant\": \"K\", \"log2 fold change IC90\": -0.07758040377349132, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.0828658757018165, \"functional effect\": -0.0347, \"times_seen\": 87.0}, {\"site\": 674, \"mutant\": \"L\", \"log2 fold change IC90\": -0.031509764383787234, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08555479767534421, \"functional effect\": 0.115, \"times_seen\": 161.0}, {\"site\": 674, \"mutant\": \"M\", \"log2 fold change IC90\": -0.5705998212253738, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.05887922583576883, \"functional effect\": 0.1552, \"times_seen\": 40.0}, {\"site\": 674, \"mutant\": \"N\", \"log2 fold change IC90\": 0.012330696186957578, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08819453245377046, \"functional effect\": 0.1295, \"times_seen\": 22.0}, {\"site\": 674, \"mutant\": \"P\", \"log2 fold change IC90\": -0.08858336162969002, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08223628895520037, \"functional effect\": -0.0622, \"times_seen\": 109.0}, {\"site\": 674, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 674, \"mutant\": \"R\", \"log2 fold change IC90\": -3.720187025007779, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.006635014385696611, \"functional effect\": 0.0838, \"times_seen\": 184.0}, {\"site\": 674, \"mutant\": \"S\", \"log2 fold change IC90\": -0.6445529116608458, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.05593710586578477, \"functional effect\": -0.0616, \"times_seen\": 72.0}, {\"site\": 674, \"mutant\": \"T\", \"log2 fold change IC90\": 0.32395465429632037, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.1094585828320719, \"functional effect\": 0.0604, \"times_seen\": 50.0}, {\"site\": 674, \"mutant\": \"V\", \"log2 fold change IC90\": 0.29819490006105, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.10752151184232836, \"functional effect\": 0.2324, \"times_seen\": 52.0}, {\"site\": 674, \"mutant\": \"W\", \"log2 fold change IC90\": -0.04157907754372425, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08495974559713632, \"functional effect\": 0.1285, \"times_seen\": 28.0}, {\"site\": 674, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03795000204080198, \"epitope\": \"all\", \"reference_site\": \"677\", \"IC90\": 0.08517372945493969, \"functional effect\": 0.2683, \"times_seen\": 19.0}, {\"site\": 675, \"mutant\": \"*\", \"log2 fold change IC90\": -0.009084871937210545, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.0868950292739876, \"functional effect\": -2.6582, \"times_seen\": 2.0}, {\"site\": 675, \"mutant\": \"-\", \"log2 fold change IC90\": 0.022913813736779615, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08884387615920286, \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 675, \"mutant\": \"A\", \"log2 fold change IC90\": -0.017284557460145757, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.0864025544878154, \"functional effect\": -0.1094, \"times_seen\": 54.0}, {\"site\": 675, \"mutant\": \"C\", \"log2 fold change IC90\": 2.9928734433717003e-05, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08744576114134775, \"functional effect\": -0.4261, \"times_seen\": 11.0}, {\"site\": 675, \"mutant\": \"D\", \"log2 fold change IC90\": 0.012963354332989601, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08823321646098778, \"functional effect\": -0.028, \"times_seen\": 23.0}, {\"site\": 675, \"mutant\": \"E\", \"log2 fold change IC90\": -0.05615953047820307, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08410543272290172, \"functional effect\": 0.0433, \"times_seen\": 13.0}, {\"site\": 675, \"mutant\": \"F\", \"log2 fold change IC90\": -1.018832874153171, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.04315493801316037, \"functional effect\": 0.0114, \"times_seen\": 24.0}, {\"site\": 675, \"mutant\": \"G\", \"log2 fold change IC90\": 0.03814235608931401, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08978664546564748, \"functional effect\": -0.1251, \"times_seen\": 33.0}, {\"site\": 675, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0014204884018801359, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08753008746538593, \"functional effect\": 0.0667, \"times_seen\": 17.0}, {\"site\": 675, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0002323796999437046, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08745803311877806, \"functional effect\": 0.065, \"times_seen\": 54.0}, {\"site\": 675, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02112808149896292, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.0861726733883001, \"functional effect\": -0.0199, \"times_seen\": 19.0}, {\"site\": 675, \"mutant\": \"L\", \"log2 fold change IC90\": -0.055569421079066525, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08413984162899664, \"functional effect\": 0.1588, \"times_seen\": 37.0}, {\"site\": 675, \"mutant\": \"M\", \"log2 fold change IC90\": -0.011967056206599477, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08672160559354601, \"functional effect\": 0.1123, \"times_seen\": 15.0}, {\"site\": 675, \"mutant\": \"N\", \"log2 fold change IC90\": 0.017713599709175507, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08852421365122239, \"functional effect\": 0.0573, \"times_seen\": 30.0}, {\"site\": 675, \"mutant\": \"P\", \"log2 fold change IC90\": 0.6035786390777014, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.13286941654181603, \"functional effect\": 0.082, \"times_seen\": 49.0}, {\"site\": 675, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.10286267867991022, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.09390625141020091, \"functional effect\": 0.084, \"times_seen\": 12.0}, {\"site\": 675, \"mutant\": \"R\", \"log2 fold change IC90\": -0.02265730826702782, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08608138053775229, \"functional effect\": -0.0321, \"times_seen\": 28.0}, {\"site\": 675, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05722239852204385, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.0840434930521246, \"functional effect\": -0.0164, \"times_seen\": 81.0}, {\"site\": 675, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 675, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04155484483438045, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08496117266387837, \"functional effect\": -0.0736, \"times_seen\": 34.0}, {\"site\": 675, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0022034206216785773, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08731049634659437, \"functional effect\": 0.0339, \"times_seen\": 1.0}, {\"site\": 675, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02017943453122204, \"epitope\": \"all\", \"reference_site\": \"678\", \"IC90\": 0.08622935503305736, \"functional effect\": 0.1426, \"times_seen\": 15.0}, {\"site\": 676, \"mutant\": \"*\", \"log2 fold change IC90\": -0.019413166935838617, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08627516673207615, \"functional effect\": -2.5024, \"times_seen\": 7.0}, {\"site\": 676, \"mutant\": \"-\", \"log2 fold change IC90\": 0.0234130994728936, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08887462843566714, \"functional effect\": -0.0797, \"times_seen\": 1.0}, {\"site\": 676, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04626150706936359, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08468444615667794, \"functional effect\": 0.0013, \"times_seen\": 41.0}, {\"site\": 676, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0019970029662780614, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08756507230471744, \"functional effect\": -0.348, \"times_seen\": 11.0}, {\"site\": 676, \"mutant\": \"D\", \"log2 fold change IC90\": 0.022140380579291033, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08879625945442475, \"functional effect\": 0.0777, \"times_seen\": 25.0}, {\"site\": 676, \"mutant\": \"E\", \"log2 fold change IC90\": 0.19900822087539843, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.10037768992704672, \"functional effect\": 0.1234, \"times_seen\": 61.0}, {\"site\": 676, \"mutant\": \"F\", \"log2 fold change IC90\": -0.016526229024303802, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08644798247869334, \"functional effect\": -0.031, \"times_seen\": 11.0}, {\"site\": 676, \"mutant\": \"G\", \"log2 fold change IC90\": 0.007218047561415725, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08788254023226283, \"functional effect\": 0.1033, \"times_seen\": 53.0}, {\"site\": 676, \"mutant\": \"H\", \"log2 fold change IC90\": -0.5425932895706417, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.06003339403333364, \"functional effect\": 0.1203, \"times_seen\": 19.0}, {\"site\": 676, \"mutant\": \"I\", \"log2 fold change IC90\": 0.16335162480621498, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.09792723487937949, \"functional effect\": 0.1608, \"times_seen\": 19.0}, {\"site\": 676, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 676, \"mutant\": \"L\", \"log2 fold change IC90\": -0.043104957629131066, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.0848699346199538, \"functional effect\": 0.0434, \"times_seen\": 64.0}, {\"site\": 676, \"mutant\": \"M\", \"log2 fold change IC90\": -0.007769861167475584, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08697426985448801, \"functional effect\": 0.1142, \"times_seen\": 48.0}, {\"site\": 676, \"mutant\": \"N\", \"log2 fold change IC90\": -0.24767341807307167, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.07364997857737157, \"functional effect\": 0.0945, \"times_seen\": 45.0}, {\"site\": 676, \"mutant\": \"P\", \"log2 fold change IC90\": -0.25280296779617245, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.07338857863681394, \"functional effect\": 0.1529, \"times_seen\": 54.0}, {\"site\": 676, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.2868102054781677, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.10667636968206456, \"functional effect\": 0.2082, \"times_seen\": 41.0}, {\"site\": 676, \"mutant\": \"R\", \"log2 fold change IC90\": 0.3892882459227036, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.11452945439775336, \"functional effect\": -0.0367, \"times_seen\": 104.0}, {\"site\": 676, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02372463368127401, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08889382201147498, \"functional effect\": 0.0645, \"times_seen\": 92.0}, {\"site\": 676, \"mutant\": \"T\", \"log2 fold change IC90\": -0.4299923612848633, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.06490664395043091, \"functional effect\": 0.0274, \"times_seen\": 77.0}, {\"site\": 676, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03907029763404752, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08510761519481179, \"functional effect\": 0.0752, \"times_seen\": 50.0}, {\"site\": 676, \"mutant\": \"W\", \"log2 fold change IC90\": 0.012134488936827358, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.08818253876865462, \"functional effect\": -0.1011, \"times_seen\": 23.0}, {\"site\": 676, \"mutant\": \"Y\", \"log2 fold change IC90\": 1.0357533476399634, \"epitope\": \"all\", \"reference_site\": \"679\", \"IC90\": 0.17927617539859075, \"functional effect\": -0.0373, \"times_seen\": 36.0}, {\"site\": 677, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03914889142331837, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08510297890814617, \"functional effect\": 0.05, \"times_seen\": 13.0}, {\"site\": 677, \"mutant\": \"C\", \"log2 fold change IC90\": -0.004279262827295962, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08718495873899362, \"functional effect\": -0.1612, \"times_seen\": 2.0}, {\"site\": 677, \"mutant\": \"F\", \"log2 fold change IC90\": 0.015035820121634028, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08836005666066257, \"functional effect\": 0.1095, \"times_seen\": 36.0}, {\"site\": 677, \"mutant\": \"G\", \"log2 fold change IC90\": -0.02938562227833172, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.0856808564704846, \"functional effect\": 0.1538, \"times_seen\": 3.0}, {\"site\": 677, \"mutant\": \"H\", \"log2 fold change IC90\": 1.8832561035140154, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.3225866047024314, \"functional effect\": 0.2677, \"times_seen\": 13.0}, {\"site\": 677, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004183417404299351, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08719075106279958, \"functional effect\": 0.0077, \"times_seen\": 1.0}, {\"site\": 677, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03903200232472689, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08510987434564707, \"functional effect\": -0.0832, \"times_seen\": 12.0}, {\"site\": 677, \"mutant\": \"P\", \"log2 fold change IC90\": 0.07899882912630439, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.09236570937892043, \"functional effect\": -0.0819, \"times_seen\": 17.0}, {\"site\": 677, \"mutant\": \"R\", \"log2 fold change IC90\": -0.35017465598320674, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.06859882511464911, \"functional effect\": -0.0276, \"times_seen\": 16.0}, {\"site\": 677, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 677, \"mutant\": \"T\", \"log2 fold change IC90\": 0.05324818868274695, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.0907317013984044, \"functional effect\": 0.0732, \"times_seen\": 10.0}, {\"site\": 677, \"mutant\": \"W\", \"log2 fold change IC90\": 0.06654282808531527, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.09157167117040982, \"functional effect\": -0.19, \"times_seen\": 8.0}, {\"site\": 677, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.011183145482975538, \"epitope\": \"all\", \"reference_site\": \"680\", \"IC90\": 0.08676873992724034, \"functional effect\": -0.0183, \"times_seen\": 4.0}, {\"site\": 678, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0012340235841369568, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08751877514597937, \"functional effect\": -2.9417, \"times_seen\": 2.0}, {\"site\": 678, \"mutant\": \"A\", \"log2 fold change IC90\": -1.1626246227736063, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.03906113583058477, \"functional effect\": -0.0278, \"times_seen\": 33.0}, {\"site\": 678, \"mutant\": \"C\", \"log2 fold change IC90\": 0.19066076847356453, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09979858028207443, \"functional effect\": -0.056, \"times_seen\": 45.0}, {\"site\": 678, \"mutant\": \"D\", \"log2 fold change IC90\": 1.515548018139608, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.2500087254995922, \"functional effect\": 0.2697, \"times_seen\": 49.0}, {\"site\": 678, \"mutant\": \"E\", \"log2 fold change IC90\": -0.053294795972607945, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08427260534201583, \"functional effect\": 0.0991, \"times_seen\": 16.0}, {\"site\": 678, \"mutant\": \"F\", \"log2 fold change IC90\": 1.597062146824007, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.26454122723751516, \"functional effect\": -0.0028, \"times_seen\": 26.0}, {\"site\": 678, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03893203925910963, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08511577173800655, \"functional effect\": 0.1376, \"times_seen\": 34.0}, {\"site\": 678, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 678, \"mutant\": \"I\", \"log2 fold change IC90\": -0.30798029017676154, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.07063475569565578, \"functional effect\": 0.0187, \"times_seen\": 20.0}, {\"site\": 678, \"mutant\": \"K\", \"log2 fold change IC90\": 0.060984865272351974, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09121957123158488, \"functional effect\": 0.062, \"times_seen\": 21.0}, {\"site\": 678, \"mutant\": \"L\", \"log2 fold change IC90\": 0.07034799435954144, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09181351393594532, \"functional effect\": -0.0037, \"times_seen\": 114.0}, {\"site\": 678, \"mutant\": \"M\", \"log2 fold change IC90\": -0.04738323681416191, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08461862757453131, \"functional effect\": 0.008, \"times_seen\": 17.0}, {\"site\": 678, \"mutant\": \"N\", \"log2 fold change IC90\": 0.5099987727318247, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.12452446403604245, \"functional effect\": -0.0425, \"times_seen\": 42.0}, {\"site\": 678, \"mutant\": \"P\", \"log2 fold change IC90\": -0.006324724946771891, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08706143494223681, \"functional effect\": 0.1077, \"times_seen\": 60.0}, {\"site\": 678, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.03816181178071305, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08516122556415438, \"functional effect\": -0.0064, \"times_seen\": 41.0}, {\"site\": 678, \"mutant\": \"R\", \"log2 fold change IC90\": 0.28745978704747377, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.10672441213333529, \"functional effect\": -0.1568, \"times_seen\": 91.0}, {\"site\": 678, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04871711151537773, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09044718706009065, \"functional effect\": -0.0007, \"times_seen\": 119.0}, {\"site\": 678, \"mutant\": \"T\", \"log2 fold change IC90\": 0.02648103858537845, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08906382439110082, \"functional effect\": -0.0108, \"times_seen\": 58.0}, {\"site\": 678, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1903862307158713, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.07663334569702719, \"functional effect\": -0.0938, \"times_seen\": 29.0}, {\"site\": 678, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0725258749088657, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.09195221952832525, \"functional effect\": -0.1172, \"times_seen\": 13.0}, {\"site\": 678, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.00519676136029516, \"epitope\": \"all\", \"reference_site\": \"681\", \"IC90\": 0.08775949871568237, \"functional effect\": -0.0357, \"times_seen\": 85.0}, {\"site\": 679, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": null, \"functional effect\": 0.7621, \"times_seen\": null}, {\"site\": 679, \"mutant\": \"G\", \"log2 fold change IC90\": 0.9110796381283214, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.16443416312152506, \"functional effect\": 0.3557, \"times_seen\": 72.0}, {\"site\": 679, \"mutant\": \"I\", \"log2 fold change IC90\": 0.010603923939313416, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.0880890349207193, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"mutant\": \"K\", \"log2 fold change IC90\": 0.07350062646256, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.09201436769714187, \"functional effect\": 0.2684, \"times_seen\": 15.0}, {\"site\": 679, \"mutant\": \"L\", \"log2 fold change IC90\": 2.2135123353565698, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.40556770156731253, \"functional effect\": 0.3728, \"times_seen\": 25.0}, {\"site\": 679, \"mutant\": \"M\", \"log2 fold change IC90\": 0.051254043734116836, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.09060637541403257, \"functional effect\": 0.397, \"times_seen\": 7.0}, {\"site\": 679, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06577864251471774, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.08354652838860194, \"functional effect\": 0.2007, \"times_seen\": 13.0}, {\"site\": 679, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 679, \"mutant\": \"S\", \"log2 fold change IC90\": 0.7919350413655172, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.15140002779411388, \"functional effect\": 0.0544, \"times_seen\": 6.0}, {\"site\": 679, \"mutant\": \"T\", \"log2 fold change IC90\": 0.008007759192662804, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.08793065910736929, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 679, \"mutant\": \"W\", \"log2 fold change IC90\": 1.158706030386013, \"epitope\": \"all\", \"reference_site\": \"682\", \"IC90\": 0.1952248168763037, \"functional effect\": 0.3201, \"times_seen\": 97.0}, {\"site\": 680, \"mutant\": \"G\", \"log2 fold change IC90\": 0.1279351354113893, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.0955525026013166, \"functional effect\": 0.1477, \"times_seen\": 20.0}, {\"site\": 680, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02012238920279197, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08623276467888707, \"functional effect\": -0.0466, \"times_seen\": 13.0}, {\"site\": 680, \"mutant\": \"L\", \"log2 fold change IC90\": -0.013651518467311273, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08662041024649351, \"functional effect\": -0.0351, \"times_seen\": 5.0}, {\"site\": 680, \"mutant\": \"M\", \"log2 fold change IC90\": 0.02533214005506699, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08899292613388737, \"functional effect\": -0.0149, \"times_seen\": 5.0}, {\"site\": 680, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": null, \"functional effect\": 0.0362, \"times_seen\": null}, {\"site\": 680, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05776556337530147, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.09101624625545301, \"functional effect\": -0.0824, \"times_seen\": 17.0}, {\"site\": 680, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 680, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00579863866646042, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08709318813824965, \"functional effect\": -0.2031, \"times_seen\": 6.0}, {\"site\": 680, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": null, \"functional effect\": 0.019, \"times_seen\": null}, {\"site\": 680, \"mutant\": \"W\", \"log2 fold change IC90\": 0.6614688219906546, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.1383094038615872, \"functional effect\": -0.0267, \"times_seen\": 50.0}, {\"site\": 680, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0054532718211337235, \"epitope\": \"all\", \"reference_site\": \"683\", \"IC90\": 0.08777510369815043, \"functional effect\": -0.0464, \"times_seen\": 1.0}, {\"site\": 681, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 681, \"mutant\": \"E\", \"log2 fold change IC90\": -0.025863448152750438, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08589029198613676, \"functional effect\": 0.2704, \"times_seen\": 8.0}, {\"site\": 681, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": null, \"functional effect\": -0.2085, \"times_seen\": null}, {\"site\": 681, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0066588763965572525, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.087041272444212, \"functional effect\": 0.0403, \"times_seen\": 2.0}, {\"site\": 681, \"mutant\": \"S\", \"log2 fold change IC90\": -0.007457032752894572, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08699313106370492, \"functional effect\": -0.022, \"times_seen\": 17.0}, {\"site\": 681, \"mutant\": \"T\", \"log2 fold change IC90\": 0.01843925020954357, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.0885687509900404, \"functional effect\": 0.0168, \"times_seen\": 60.0}, {\"site\": 681, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04095793328253313, \"epitope\": \"all\", \"reference_site\": \"684\", \"IC90\": 0.08996204502635935, \"functional effect\": 0.0507, \"times_seen\": 14.0}, {\"site\": 682, \"mutant\": \"G\", \"log2 fold change IC90\": 0.04625773377155779, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.09029313211495495, \"functional effect\": 0.4033, \"times_seen\": 35.0}, {\"site\": 682, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": null, \"functional effect\": -0.0979, \"times_seen\": null}, {\"site\": 682, \"mutant\": \"K\", \"log2 fold change IC90\": 1.4713399603741175, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.24246397160853675, \"functional effect\": 0.4203, \"times_seen\": 24.0}, {\"site\": 682, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06424887888695718, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.08363516404655592, \"functional effect\": 0.1163, \"times_seen\": 6.0}, {\"site\": 682, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 682, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03090199581311454, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.08933716786168769, \"functional effect\": 0.3921, \"times_seen\": 7.0}, {\"site\": 682, \"mutant\": \"W\", \"log2 fold change IC90\": 0.03018765658658639, \"epitope\": \"all\", \"reference_site\": \"685\", \"IC90\": 0.08929294420739257, \"functional effect\": -0.1572, \"times_seen\": 3.0}, {\"site\": 683, \"mutant\": \"A\", \"log2 fold change IC90\": 0.024118141178998527, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.0889180718740626, \"functional effect\": 0.1162, \"times_seen\": 1.0}, {\"site\": 683, \"mutant\": \"C\", \"log2 fold change IC90\": 0.033197574192604815, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08947943196540185, \"functional effect\": -0.2995, \"times_seen\": 2.0}, {\"site\": 683, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0019798362939053085, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08756403037144557, \"functional effect\": 0.0832, \"times_seen\": 2.0}, {\"site\": 683, \"mutant\": \"G\", \"log2 fold change IC90\": 0.020729476600815703, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08870946234830221, \"functional effect\": 0.355, \"times_seen\": 11.0}, {\"site\": 683, \"mutant\": \"I\", \"log2 fold change IC90\": 0.026874699793423197, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08908813012142017, \"functional effect\": 0.4224, \"times_seen\": 13.0}, {\"site\": 683, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0032766547083521295, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08764277584117217, \"functional effect\": 0.1903, \"times_seen\": 5.0}, {\"site\": 683, \"mutant\": \"P\", \"log2 fold change IC90\": 0.003822073987117868, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08767591596801523, \"functional effect\": 0.0474, \"times_seen\": 3.0}, {\"site\": 683, \"mutant\": \"R\", \"log2 fold change IC90\": -0.016526173420137458, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.0864479858105604, \"functional effect\": -0.0649, \"times_seen\": 6.0}, {\"site\": 683, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 683, \"mutant\": \"T\", \"log2 fold change IC90\": 0.03821475258785994, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08979115120085972, \"functional effect\": 0.397, \"times_seen\": 2.0}, {\"site\": 683, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0051189161937293445, \"epitope\": \"all\", \"reference_site\": \"686\", \"IC90\": 0.08713423156287844, \"functional effect\": 0.1546, \"times_seen\": 6.0}, {\"site\": 684, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0012250572860110726, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08751823122160948, \"functional effect\": 0.0484, \"times_seen\": 10.0}, {\"site\": 684, \"mutant\": \"E\", \"log2 fold change IC90\": 0.007289266925547514, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08788687870501459, \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 684, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": null, \"functional effect\": 0.9512, \"times_seen\": null}, {\"site\": 684, \"mutant\": \"I\", \"log2 fold change IC90\": 0.1141997647796339, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.09464709909740592, \"functional effect\": 0.1331, \"times_seen\": 24.0}, {\"site\": 684, \"mutant\": \"L\", \"log2 fold change IC90\": -0.011495819713781308, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.08674993663999805, \"functional effect\": -0.1648, \"times_seen\": 11.0}, {\"site\": 684, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02583949166393072, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.0858917182382866, \"functional effect\": 0.0449, \"times_seen\": 19.0}, {\"site\": 684, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"687\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 685, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": null, \"functional effect\": -2.9234, \"times_seen\": null}, {\"site\": 685, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 685, \"mutant\": \"C\", \"log2 fold change IC90\": -0.1719261188626855, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.07762021368658838, \"functional effect\": -0.2151, \"times_seen\": 18.0}, {\"site\": 685, \"mutant\": \"D\", \"log2 fold change IC90\": -0.06254111950625423, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08373422400067093, \"functional effect\": 0.1009, \"times_seen\": 28.0}, {\"site\": 685, \"mutant\": \"E\", \"log2 fold change IC90\": 1.974205882751515, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.3435776786956878, \"functional effect\": 0.2832, \"times_seen\": 13.0}, {\"site\": 685, \"mutant\": \"F\", \"log2 fold change IC90\": -0.017429465561056314, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08639387642283401, \"functional effect\": -0.4225, \"times_seen\": 6.0}, {\"site\": 685, \"mutant\": \"G\", \"log2 fold change IC90\": -0.039672719747832506, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08507208446586437, \"functional effect\": 0.0176, \"times_seen\": 37.0}, {\"site\": 685, \"mutant\": \"H\", \"log2 fold change IC90\": 0.027945546400535703, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08915428071690878, \"functional effect\": 0.1275, \"times_seen\": 8.0}, {\"site\": 685, \"mutant\": \"I\", \"log2 fold change IC90\": -0.006572358284959125, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08704649244713686, \"functional effect\": -0.5499, \"times_seen\": 1.0}, {\"site\": 685, \"mutant\": \"K\", \"log2 fold change IC90\": -0.010429856255632025, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08681405721345176, \"functional effect\": -0.154, \"times_seen\": 1.0}, {\"site\": 685, \"mutant\": \"L\", \"log2 fold change IC90\": -2.3524436422181734, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.017122755424320454, \"functional effect\": -0.064, \"times_seen\": 14.0}, {\"site\": 685, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02379219044978382, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08601369207413367, \"functional effect\": -0.099, \"times_seen\": 7.0}, {\"site\": 685, \"mutant\": \"N\", \"log2 fold change IC90\": 0.006860879683140043, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08786078585285509, \"functional effect\": 0.0169, \"times_seen\": 4.0}, {\"site\": 685, \"mutant\": \"P\", \"log2 fold change IC90\": 0.07455722966266462, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.09208178200394043, \"functional effect\": 0.0709, \"times_seen\": 20.0}, {\"site\": 685, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.019046251874645256, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08629711155267622, \"functional effect\": 0.2707, \"times_seen\": 7.0}, {\"site\": 685, \"mutant\": \"R\", \"log2 fold change IC90\": 0.009423159332726031, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08801696850392624, \"functional effect\": 0.0171, \"times_seen\": 26.0}, {\"site\": 685, \"mutant\": \"S\", \"log2 fold change IC90\": 0.025252397074527134, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08898800730845785, \"functional effect\": -0.0361, \"times_seen\": 74.0}, {\"site\": 685, \"mutant\": \"T\", \"log2 fold change IC90\": -2.053059357263109, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.021071589805163025, \"functional effect\": -0.0197, \"times_seen\": 65.0}, {\"site\": 685, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0009636048863994164, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08738556103502973, \"functional effect\": 0.0917, \"times_seen\": 90.0}, {\"site\": 685, \"mutant\": \"W\", \"log2 fold change IC90\": 0.033977820057416244, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08952783778736453, \"functional effect\": -0.1542, \"times_seen\": 7.0}, {\"site\": 685, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.020975558528833455, \"epitope\": \"all\", \"reference_site\": \"688\", \"IC90\": 0.08618178411960666, \"functional effect\": -0.2307, \"times_seen\": 9.0}, {\"site\": 686, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": null, \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 686, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": null, \"functional effect\": -0.173, \"times_seen\": null}, {\"site\": 686, \"mutant\": \"D\", \"log2 fold change IC90\": 0.009574784748473213, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08802621946160738, \"functional effect\": -0.3588, \"times_seen\": 3.0}, {\"site\": 686, \"mutant\": \"G\", \"log2 fold change IC90\": -0.030083050122869447, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08563944662848662, \"functional effect\": 0.0158, \"times_seen\": 9.0}, {\"site\": 686, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0200205204574742, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.08866588025620302, \"functional effect\": -0.1987, \"times_seen\": 20.0}, {\"site\": 686, \"mutant\": \"N\", \"log2 fold change IC90\": -0.04738807237336643, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.0846183439541638, \"functional effect\": 0.0178, \"times_seen\": 46.0}, {\"site\": 686, \"mutant\": \"R\", \"log2 fold change IC90\": 0.7348004330809051, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.14552135301185215, \"functional effect\": 0.0532, \"times_seen\": 40.0}, {\"site\": 686, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 686, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006598815160737022, \"epitope\": \"all\", \"reference_site\": \"689\", \"IC90\": 0.0870448961589014, \"functional effect\": 0.2043, \"times_seen\": 4.0}, {\"site\": 687, \"mutant\": \"*\", \"log2 fold change IC90\": -0.003159394158701801, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08725266092467399, \"functional effect\": -2.8604, \"times_seen\": 1.0}, {\"site\": 687, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": null, \"functional effect\": -2.9395, \"times_seen\": null}, {\"site\": 687, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0012778055776410074, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08752143115052546, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 687, \"mutant\": \"K\", \"log2 fold change IC90\": -0.015738988201300114, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08649516774677819, \"functional effect\": 0.2871, \"times_seen\": 23.0}, {\"site\": 687, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0073139742724009135, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.0870017577809549, \"functional effect\": -0.3511, \"times_seen\": 34.0}, {\"site\": 687, \"mutant\": \"P\", \"log2 fold change IC90\": -0.011691214893622731, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08673818823082394, \"functional effect\": -0.041, \"times_seen\": 5.0}, {\"site\": 687, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 687, \"mutant\": \"R\", \"log2 fold change IC90\": 0.03939031762674488, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08986434640301791, \"functional effect\": 0.0963, \"times_seen\": 29.0}, {\"site\": 687, \"mutant\": \"S\", \"log2 fold change IC90\": 0.024709478044553677, \"epitope\": \"all\", \"reference_site\": \"690\", \"IC90\": 0.08895452539323419, \"functional effect\": 0.155, \"times_seen\": 4.0}, {\"site\": 688, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03471038482972044, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08536520465180401, \"functional effect\": -0.1149, \"times_seen\": 9.0}, {\"site\": 688, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0019365591485738518, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08732664803636771, \"functional effect\": 0.0782, \"times_seen\": 1.0}, {\"site\": 688, \"mutant\": \"D\", \"log2 fold change IC90\": 0.30278146648671894, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.10786388447385352, \"functional effect\": -0.8101, \"times_seen\": 8.0}, {\"site\": 688, \"mutant\": \"F\", \"log2 fold change IC90\": -0.12409371382071048, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08023684117074188, \"functional effect\": -0.682, \"times_seen\": 35.0}, {\"site\": 688, \"mutant\": \"G\", \"log2 fold change IC90\": -0.026315223146152148, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.0858633999472073, \"functional effect\": 0.1487, \"times_seen\": 6.0}, {\"site\": 688, \"mutant\": \"I\", \"log2 fold change IC90\": -0.009248552821606042, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08688517116258457, \"functional effect\": -0.0558, \"times_seen\": 4.0}, {\"site\": 688, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0794633969725902, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08275779042259596, \"functional effect\": 0.0284, \"times_seen\": 26.0}, {\"site\": 688, \"mutant\": \"P\", \"log2 fold change IC90\": 0.04277382613012809, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.09007534983617796, \"functional effect\": -0.8109, \"times_seen\": 15.0}, {\"site\": 688, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0028832615608301326, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.08726936272868116, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 688, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 688, \"mutant\": \"T\", \"log2 fold change IC90\": 0.01285439128700078, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.0882265526847265, \"functional effect\": -0.0433, \"times_seen\": 8.0}, {\"site\": 688, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07137065848864153, \"epitope\": \"all\", \"reference_site\": \"691\", \"IC90\": 0.0832233213110615, \"functional effect\": -0.498, \"times_seen\": 25.0}, {\"site\": 689, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009053951983150482, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08689689163507501, \"functional effect\": -0.0477, \"times_seen\": 4.0}, {\"site\": 689, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 689, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0448084261547815, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.09020247067144156, \"functional effect\": -0.3436, \"times_seen\": 3.0}, {\"site\": 689, \"mutant\": \"M\", \"log2 fold change IC90\": -0.022156277102550682, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08611128078912444, \"functional effect\": -0.636, \"times_seen\": 6.0}, {\"site\": 689, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": null, \"functional effect\": -3.2584, \"times_seen\": null}, {\"site\": 689, \"mutant\": \"S\", \"log2 fold change IC90\": 0.012897551062902735, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08822919211654882, \"functional effect\": -2.4933, \"times_seen\": 3.0}, {\"site\": 689, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0005103848508361595, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08747488777327532, \"functional effect\": -2.0274, \"times_seen\": 1.0}, {\"site\": 689, \"mutant\": \"V\", \"log2 fold change IC90\": 0.016455679326405258, \"epitope\": \"all\", \"reference_site\": \"692\", \"IC90\": 0.08844706090825863, \"functional effect\": -1.4086, \"times_seen\": 2.0}, {\"site\": 690, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"F\", \"log2 fold change IC90\": 0.001600242491148554, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.08754099404712423, \"functional effect\": -0.3145, \"times_seen\": 6.0}, {\"site\": 690, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -1.3379, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -1.3074, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03403033830441629, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.08953109691735833, \"functional effect\": -1.368, \"times_seen\": 1.0}, {\"site\": 690, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": null, \"functional effect\": -3.066, \"times_seen\": null}, {\"site\": 690, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04057521999491009, \"epitope\": \"all\", \"reference_site\": \"693\", \"IC90\": 0.08993818336277286, \"functional effect\": -0.1459, \"times_seen\": 19.0}, {\"site\": 691, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -3.0186, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -3.2784, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": null, \"functional effect\": -3.0118, \"times_seen\": null}, {\"site\": 691, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02863557923042007, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.08572541269131223, \"functional effect\": -2.0572, \"times_seen\": 14.0}, {\"site\": 691, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02979738529746307, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.08565640558314028, \"functional effect\": -1.6896, \"times_seen\": 13.0}, {\"site\": 691, \"mutant\": \"V\", \"log2 fold change IC90\": -0.010228949732851258, \"epitope\": \"all\", \"reference_site\": \"694\", \"IC90\": 0.0868261475890047, \"functional effect\": 0.1418, \"times_seen\": 21.0}, {\"site\": 693, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": null, \"functional effect\": -1.3269, \"times_seen\": null}, {\"site\": 693, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0002423763747275596, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08742925752847135, \"functional effect\": -0.8277, \"times_seen\": 5.0}, {\"site\": 693, \"mutant\": \"I\", \"log2 fold change IC90\": -0.017766628946143368, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08637368820044274, \"functional effect\": -0.1373, \"times_seen\": 14.0}, {\"site\": 693, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02750448941163384, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08579264877295957, \"functional effect\": -0.2243, \"times_seen\": 7.0}, {\"site\": 693, \"mutant\": \"N\", \"log2 fold change IC90\": 0.004883235219816376, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.08774042891465436, \"functional effect\": -1.8929, \"times_seen\": 3.0}, {\"site\": 693, \"mutant\": \"R\", \"log2 fold change IC90\": 0.02476490404480294, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.0889579429472681, \"functional effect\": -0.2672, \"times_seen\": 1.0}, {\"site\": 693, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": null, \"functional effect\": -0.3019, \"times_seen\": null}, {\"site\": 693, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"696\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"I\", \"log2 fold change IC90\": -0.3534009152078155, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.06844559085016581, \"functional effect\": -0.307, \"times_seen\": 45.0}, {\"site\": 694, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": null, \"functional effect\": -2.9442, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"L\", \"log2 fold change IC90\": -0.013305255779830546, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.08664120259335506, \"functional effect\": -0.48, \"times_seen\": 7.0}, {\"site\": 694, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": null, \"functional effect\": -2.6723, \"times_seen\": null}, {\"site\": 694, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03079440989773105, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.08559723019398308, \"functional effect\": -2.7727, \"times_seen\": 4.0}, {\"site\": 694, \"mutant\": \"V\", \"log2 fold change IC90\": 0.010594628970261524, \"epitope\": \"all\", \"reference_site\": \"697\", \"IC90\": 0.08808846738413494, \"functional effect\": -1.9839, \"times_seen\": 2.0}, {\"site\": 695, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00199544789034998, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08732308356062878, \"functional effect\": -0.6287, \"times_seen\": 1.0}, {\"site\": 695, \"mutant\": \"C\", \"log2 fold change IC90\": -0.00555522371789397, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08710788394841737, \"functional effect\": -0.3265, \"times_seen\": 1.0}, {\"site\": 695, \"mutant\": \"G\", \"log2 fold change IC90\": -0.055038856363309296, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08417079054029751, \"functional effect\": -0.3187, \"times_seen\": 4.0}, {\"site\": 695, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011117713690193827, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08677267531399822, \"functional effect\": -1.1388, \"times_seen\": 3.0}, {\"site\": 695, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010459886379667141, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08681225017197779, \"functional effect\": -0.1677, \"times_seen\": 2.0}, {\"site\": 695, \"mutant\": \"N\", \"log2 fold change IC90\": -0.008846849420599077, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.08690936680149192, \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 695, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": null, \"functional effect\": -1.3615, \"times_seen\": null}, {\"site\": 695, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"698\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": null, \"functional effect\": -3.0141, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04691832393662578, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.0846459005795454, \"functional effect\": -0.3115, \"times_seen\": 10.0}, {\"site\": 696, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013772551248246976, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08661314365924741, \"functional effect\": -0.5968, \"times_seen\": 3.0}, {\"site\": 696, \"mutant\": \"P\", \"log2 fold change IC90\": -0.019016775255704648, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08629887476180043, \"functional effect\": -1.1541, \"times_seen\": 7.0}, {\"site\": 696, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": null, \"functional effect\": -0.7797, \"times_seen\": null}, {\"site\": 696, \"mutant\": \"R\", \"log2 fold change IC90\": 0.02955578569052915, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08925384428875618, \"functional effect\": -2.2536, \"times_seen\": 1.0}, {\"site\": 696, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005988613071807994, \"epitope\": \"all\", \"reference_site\": \"699\", \"IC90\": 0.08708172044282597, \"functional effect\": -1.0615, \"times_seen\": 2.0}, {\"site\": 697, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": null, \"functional effect\": -2.3439, \"times_seen\": null}, {\"site\": 697, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": null, \"functional effect\": -3.0251, \"times_seen\": null}, {\"site\": 697, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0032269961872786585, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.08763975917056226, \"functional effect\": -2.1499, \"times_seen\": 1.0}, {\"site\": 697, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 697, \"mutant\": \"R\", \"log2 fold change IC90\": -0.015153061734961325, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.08653030344720568, \"functional effect\": -2.9319, \"times_seen\": 11.0}, {\"site\": 697, \"mutant\": \"V\", \"log2 fold change IC90\": -0.006825312995164724, \"epitope\": \"all\", \"reference_site\": \"700\", \"IC90\": 0.08703123150187332, \"functional effect\": -2.4878, \"times_seen\": 2.0}, {\"site\": 698, \"mutant\": \"*\", \"log2 fold change IC90\": -0.016211827096043876, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08646682386470463, \"functional effect\": -2.4326, \"times_seen\": 4.0}, {\"site\": 698, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 698, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04777048056868837, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08459591755144104, \"functional effect\": -0.3332, \"times_seen\": 18.0}, {\"site\": 698, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04266460033640465, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08489584362906805, \"functional effect\": 0.1895, \"times_seen\": 13.0}, {\"site\": 698, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0006373312889269618, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08748258525173544, \"functional effect\": 0.3037, \"times_seen\": 36.0}, {\"site\": 698, \"mutant\": \"F\", \"log2 fold change IC90\": -0.028979346515493356, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08570498835990494, \"functional effect\": -1.6567, \"times_seen\": 6.0}, {\"site\": 698, \"mutant\": \"G\", \"log2 fold change IC90\": 0.23022683019590418, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.10257344327064905, \"functional effect\": -0.5186, \"times_seen\": 45.0}, {\"site\": 698, \"mutant\": \"H\", \"log2 fold change IC90\": 0.02987706060957238, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08927372251239611, \"functional effect\": -0.3038, \"times_seen\": 15.0}, {\"site\": 698, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02901987741106053, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.0857025806084121, \"functional effect\": -1.6607, \"times_seen\": 4.0}, {\"site\": 698, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0009048157862688192, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08749880656260607, \"functional effect\": 0.269, \"times_seen\": 16.0}, {\"site\": 698, \"mutant\": \"L\", \"log2 fold change IC90\": 0.04247628609696827, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.09005677469846758, \"functional effect\": -2.1994, \"times_seen\": 10.0}, {\"site\": 698, \"mutant\": \"M\", \"log2 fold change IC90\": -1.9188852810620551, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.023125318611281708, \"functional effect\": -1.2184, \"times_seen\": 11.0}, {\"site\": 698, \"mutant\": \"N\", \"log2 fold change IC90\": -0.010876696399166018, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08678717280762738, \"functional effect\": -0.1154, \"times_seen\": 16.0}, {\"site\": 698, \"mutant\": \"P\", \"log2 fold change IC90\": 0.1333737190866533, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.09591339039025516, \"functional effect\": 0.2828, \"times_seen\": 43.0}, {\"site\": 698, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005578837437435446, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08710645819713285, \"functional effect\": 0.1819, \"times_seen\": 16.0}, {\"site\": 698, \"mutant\": \"R\", \"log2 fold change IC90\": 0.307592015071708, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.10822414807309412, \"functional effect\": 0.0393, \"times_seen\": 51.0}, {\"site\": 698, \"mutant\": \"S\", \"log2 fold change IC90\": 0.9448283188471612, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.16832608306807922, \"functional effect\": 0.1561, \"times_seen\": 71.0}, {\"site\": 698, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07012097134195044, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.09179906726461687, \"functional effect\": -0.0478, \"times_seen\": 78.0}, {\"site\": 698, \"mutant\": \"V\", \"log2 fold change IC90\": -1.8485352526772358, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.024280923112182964, \"functional effect\": -0.3771, \"times_seen\": 68.0}, {\"site\": 698, \"mutant\": \"W\", \"log2 fold change IC90\": 0.003024488106883125, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.0876274582245249, \"functional effect\": -1.306, \"times_seen\": 9.0}, {\"site\": 698, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0461609339173664, \"epitope\": \"all\", \"reference_site\": \"701\", \"IC90\": 0.08469034988429086, \"functional effect\": -1.6371, \"times_seen\": 6.0}, {\"site\": 699, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": null, \"functional effect\": -2.7972, \"times_seen\": null}, {\"site\": 699, \"mutant\": \"A\", \"log2 fold change IC90\": 0.00299640094119242, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08762575226248126, \"functional effect\": -0.9622, \"times_seen\": 6.0}, {\"site\": 699, \"mutant\": \"D\", \"log2 fold change IC90\": -0.036379464453454434, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08526650123090972, \"functional effect\": -0.0147, \"times_seen\": 23.0}, {\"site\": 699, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 699, \"mutant\": \"G\", \"log2 fold change IC90\": -0.026016726360653542, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08588116711197816, \"functional effect\": -1.3361, \"times_seen\": 5.0}, {\"site\": 699, \"mutant\": \"K\", \"log2 fold change IC90\": 1.0210237614876327, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.17745511878627643, \"functional effect\": -1.9836, \"times_seen\": 23.0}, {\"site\": 699, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.21475785785711318, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.07534964244442356, \"functional effect\": -1.0118, \"times_seen\": 29.0}, {\"site\": 699, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0188508863344914, \"epitope\": \"all\", \"reference_site\": \"702\", \"IC90\": 0.08859402542303077, \"functional effect\": -0.4209, \"times_seen\": 9.0}, {\"site\": 700, \"mutant\": \"D\", \"log2 fold change IC90\": 0.02560933929780554, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08901002686627593, \"functional effect\": -1.3029, \"times_seen\": 2.0}, {\"site\": 700, \"mutant\": \"F\", \"log2 fold change IC90\": 0.06576636102307874, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.09152240001188261, \"functional effect\": 0.2062, \"times_seen\": 5.0}, {\"site\": 700, \"mutant\": \"H\", \"log2 fold change IC90\": -0.003960233761744405, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08720424043798482, \"functional effect\": 0.1572, \"times_seen\": 3.0}, {\"site\": 700, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0006583290872350457, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08740405386881095, \"functional effect\": 0.2645, \"times_seen\": 8.0}, {\"site\": 700, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03259488621222489, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08944205960749592, \"functional effect\": 0.2939, \"times_seen\": 13.0}, {\"site\": 700, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 700, \"mutant\": \"S\", \"log2 fold change IC90\": 0.026580928179688972, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.0890699912226429, \"functional effect\": 0.2507, \"times_seen\": 31.0}, {\"site\": 700, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07840564156852609, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.09232773951999619, \"functional effect\": 0.3242, \"times_seen\": 21.0}, {\"site\": 700, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.016060759746370695, \"epitope\": \"all\", \"reference_site\": \"703\", \"IC90\": 0.08647587844481992, \"functional effect\": 0.3651, \"times_seen\": 11.0}, {\"site\": 701, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0004652733033879717, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08747215256885338, \"functional effect\": -0.0676, \"times_seen\": 3.0}, {\"site\": 701, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": null, \"functional effect\": -0.8183, \"times_seen\": null}, {\"site\": 701, \"mutant\": \"F\", \"log2 fold change IC90\": -0.002108414578903759, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08731624620893418, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 701, \"mutant\": \"L\", \"log2 fold change IC90\": 0.7121518184037327, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.14325467760962363, \"functional effect\": 0.3483, \"times_seen\": 21.0}, {\"site\": 701, \"mutant\": \"P\", \"log2 fold change IC90\": -0.05104546267630959, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08440409884529533, \"functional effect\": -1.5507, \"times_seen\": 15.0}, {\"site\": 701, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 701, \"mutant\": \"T\", \"log2 fold change IC90\": 0.006976068689455062, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.08786780119592442, \"functional effect\": 0.3651, \"times_seen\": 7.0}, {\"site\": 701, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.5943543595819865, \"epitope\": \"all\", \"reference_site\": \"704\", \"IC90\": 0.05791769406533911, \"functional effect\": 0.4444, \"times_seen\": 6.0}, {\"site\": 702, \"mutant\": \"A\", \"log2 fold change IC90\": -0.019315786467947998, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.08628099041582006, \"functional effect\": -2.517, \"times_seen\": 2.0}, {\"site\": 702, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": null, \"functional effect\": -2.9829, \"times_seen\": null}, {\"site\": 702, \"mutant\": \"F\", \"log2 fold change IC90\": -0.020377553442811593, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.08621751435119202, \"functional effect\": -2.0341, \"times_seen\": 5.0}, {\"site\": 702, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02387770492600693, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.0889032542265214, \"functional effect\": 0.2691, \"times_seen\": 20.0}, {\"site\": 702, \"mutant\": \"L\", \"log2 fold change IC90\": -0.5385901067505267, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.06020020571509857, \"functional effect\": -0.0799, \"times_seen\": 40.0}, {\"site\": 702, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0013660801399280951, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.08736118608436423, \"functional effect\": -1.7662, \"times_seen\": 4.0}, {\"site\": 702, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"705\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": null, \"functional effect\": -2.0658, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": null, \"functional effect\": -2.8496, \"times_seen\": null}, {\"site\": 703, \"mutant\": \"G\", \"log2 fold change IC90\": -0.022988722355390862, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08606160830250964, \"functional effect\": -1.7527, \"times_seen\": 4.0}, {\"site\": 703, \"mutant\": \"L\", \"log2 fold change IC90\": -0.021368409795043706, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.0861583196916909, \"functional effect\": -1.2316, \"times_seen\": 2.0}, {\"site\": 703, \"mutant\": \"P\", \"log2 fold change IC90\": -0.12087949920650116, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08041580202016953, \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 703, \"mutant\": \"S\", \"log2 fold change IC90\": 0.010974267605673481, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.0881116505136378, \"functional effect\": -1.5893, \"times_seen\": 12.0}, {\"site\": 703, \"mutant\": \"T\", \"log2 fold change IC90\": -0.023671935659246003, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.08602086198137841, \"functional effect\": -1.6831, \"times_seen\": 4.0}, {\"site\": 703, \"mutant\": \"V\", \"log2 fold change IC90\": -1.7114857498070535, \"epitope\": \"all\", \"reference_site\": \"706\", \"IC90\": 0.026700611330769494, \"functional effect\": -2.1539, \"times_seen\": 3.0}, {\"site\": 704, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": null, \"functional effect\": -2.2896, \"times_seen\": null}, {\"site\": 704, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006247311732886324, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.08706610667542967, \"functional effect\": -2.6432, \"times_seen\": 1.0}, {\"site\": 704, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0002725341823010942, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.08742742994392157, \"functional effect\": -2.3384, \"times_seen\": 1.0}, {\"site\": 704, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0048389658999809645, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.08715114131850879, \"functional effect\": -2.1444, \"times_seen\": 1.0}, {\"site\": 704, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"707\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": null, \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00761445651006971, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08698363907960095, \"functional effect\": -0.8247, \"times_seen\": 4.0}, {\"site\": 705, \"mutant\": \"C\", \"log2 fold change IC90\": -0.012913246081861842, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08666474797578007, \"functional effect\": -2.8552, \"times_seen\": 3.0}, {\"site\": 705, \"mutant\": \"F\", \"log2 fold change IC90\": 0.018692894418779735, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08858432387627033, \"functional effect\": -2.5027, \"times_seen\": 5.0}, {\"site\": 705, \"mutant\": \"G\", \"log2 fold change IC90\": 0.03417813910101046, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08954026964265768, \"functional effect\": -0.5849, \"times_seen\": 17.0}, {\"site\": 705, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": null, \"functional effect\": -2.4402, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": null, \"functional effect\": -2.8747, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"N\", \"log2 fold change IC90\": -0.003798838247595828, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08721399659580603, \"functional effect\": -1.0821, \"times_seen\": 16.0}, {\"site\": 705, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0095398965604452, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08686762698719061, \"functional effect\": -2.0092, \"times_seen\": 2.0}, {\"site\": 705, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 705, \"mutant\": \"T\", \"log2 fold change IC90\": -0.005489586874677371, \"epitope\": \"all\", \"reference_site\": \"708\", \"IC90\": 0.08711184709823278, \"functional effect\": 0.2883, \"times_seen\": 3.0}, {\"site\": 706, \"mutant\": \"-\", \"log2 fold change IC90\": -0.002792949887093931, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08727482589912397, \"functional effect\": -1.1873, \"times_seen\": 1.0}, {\"site\": 706, \"mutant\": \"D\", \"log2 fold change IC90\": -0.007551685727323667, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08698742376710553, \"functional effect\": 0.2955, \"times_seen\": 2.0}, {\"site\": 706, \"mutant\": \"I\", \"log2 fold change IC90\": 0.014614037723345453, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08833422773064224, \"functional effect\": -1.7003, \"times_seen\": 4.0}, {\"site\": 706, \"mutant\": \"K\", \"log2 fold change IC90\": -0.020599822247441814, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08620423227343042, \"functional effect\": -1.7224, \"times_seen\": 6.0}, {\"site\": 706, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 706, \"mutant\": \"S\", \"log2 fold change IC90\": -0.09847016330417804, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08167464960880821, \"functional effect\": -2.0355, \"times_seen\": 13.0}, {\"site\": 706, \"mutant\": \"T\", \"log2 fold change IC90\": 0.012401668022206193, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08819887119592504, \"functional effect\": -2.0548, \"times_seen\": 7.0}, {\"site\": 706, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": null, \"functional effect\": -2.9375, \"times_seen\": null}, {\"site\": 706, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01616109274987699, \"epitope\": \"all\", \"reference_site\": \"709\", \"IC90\": 0.08646986464240541, \"functional effect\": -1.5874, \"times_seen\": 14.0}, {\"site\": 707, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03463932162598819, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08536940961138702, \"functional effect\": 0.1446, \"times_seen\": 40.0}, {\"site\": 707, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 707, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03784158585326867, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08976792887274994, \"functional effect\": -0.4409, \"times_seen\": 16.0}, {\"site\": 707, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 707, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.011970978392380168, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08672136982799866, \"functional effect\": -1.1788, \"times_seen\": 1.0}, {\"site\": 707, \"mutant\": \"S\", \"log2 fold change IC90\": 0.11275343527027983, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.09455226110769183, \"functional effect\": -0.7601, \"times_seen\": 12.0}, {\"site\": 707, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05263735825980562, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08431101721222012, \"functional effect\": 0.0623, \"times_seen\": 8.0}, {\"site\": 707, \"mutant\": \"V\", \"log2 fold change IC90\": -0.017824507305443427, \"epitope\": \"all\", \"reference_site\": \"710\", \"IC90\": 0.08637022311118926, \"functional effect\": -0.2966, \"times_seen\": 5.0}, {\"site\": 708, \"mutant\": \"A\", \"log2 fold change IC90\": 0.03340409865198962, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08949224202820306, \"functional effect\": -1.6379, \"times_seen\": 7.0}, {\"site\": 708, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": null, \"functional effect\": -0.8443, \"times_seen\": null}, {\"site\": 708, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009896107778517614, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08684618142689442, \"functional effect\": -2.7301, \"times_seen\": 1.0}, {\"site\": 708, \"mutant\": \"G\", \"log2 fold change IC90\": -0.08048943619683037, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08269895432139115, \"functional effect\": -0.1169, \"times_seen\": 8.0}, {\"site\": 708, \"mutant\": \"I\", \"log2 fold change IC90\": -0.016729713034929507, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08643579033745442, \"functional effect\": -1.7186, \"times_seen\": 2.0}, {\"site\": 708, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004717684700877243, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08715846805001749, \"functional effect\": -2.5205, \"times_seen\": 1.0}, {\"site\": 708, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": null, \"functional effect\": -2.9811, \"times_seen\": null}, {\"site\": 708, \"mutant\": \"N\", \"log2 fold change IC90\": -0.09154143060892438, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08206784629005556, \"functional effect\": -1.7215, \"times_seen\": 17.0}, {\"site\": 708, \"mutant\": \"R\", \"log2 fold change IC90\": -0.014467613407164116, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08657142519672409, \"functional effect\": -1.0857, \"times_seen\": 4.0}, {\"site\": 708, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 708, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02328917349887522, \"epitope\": \"all\", \"reference_site\": \"711\", \"IC90\": 0.08604368724809569, \"functional effect\": -1.4944, \"times_seen\": 6.0}, {\"site\": 709, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 709, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005546265899908366, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08710842481046366, \"functional effect\": -1.5703, \"times_seen\": 1.0}, {\"site\": 709, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": null, \"functional effect\": -3.249, \"times_seen\": null}, {\"site\": 709, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0014245451006479227, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.0875303335906495, \"functional effect\": -2.8567, \"times_seen\": 1.0}, {\"site\": 709, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02704624140615604, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08581990370452783, \"functional effect\": -0.9693, \"times_seen\": 9.0}, {\"site\": 709, \"mutant\": \"V\", \"log2 fold change IC90\": -0.021861859230346125, \"epitope\": \"all\", \"reference_site\": \"712\", \"IC90\": 0.08612885573493434, \"functional effect\": -1.6063, \"times_seen\": 26.0}, {\"site\": 710, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 710, \"mutant\": \"D\", \"log2 fold change IC90\": 0.07827280127664349, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.0923192385694307, \"functional effect\": -0.4359, \"times_seen\": 16.0}, {\"site\": 710, \"mutant\": \"G\", \"log2 fold change IC90\": 0.017611799293182216, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08851796736661001, \"functional effect\": -0.5815, \"times_seen\": 1.0}, {\"site\": 710, \"mutant\": \"P\", \"log2 fold change IC90\": 0.002369792106415379, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08758770184521425, \"functional effect\": -2.866, \"times_seen\": 1.0}, {\"site\": 710, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03418686552326897, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08954081124607562, \"functional effect\": -0.2114, \"times_seen\": 6.0}, {\"site\": 710, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02591599405537926, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08902894857082831, \"functional effect\": -2.0541, \"times_seen\": 10.0}, {\"site\": 710, \"mutant\": \"T\", \"log2 fold change IC90\": 0.003875198133985733, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08767914450478895, \"functional effect\": -2.1178, \"times_seen\": 11.0}, {\"site\": 710, \"mutant\": \"V\", \"log2 fold change IC90\": -0.012683177966200247, \"epitope\": \"all\", \"reference_site\": \"713\", \"IC90\": 0.08667856959754412, \"functional effect\": -2.4829, \"times_seen\": 2.0}, {\"site\": 711, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 711, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": null, \"functional effect\": -3.2101, \"times_seen\": null}, {\"site\": 711, \"mutant\": \"M\", \"log2 fold change IC90\": -0.004356780670220818, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.08718027430591511, \"functional effect\": -2.012, \"times_seen\": 1.0}, {\"site\": 711, \"mutant\": \"T\", \"log2 fold change IC90\": -0.002693060250250812, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.08728086886193227, \"functional effect\": -2.5336, \"times_seen\": 1.0}, {\"site\": 711, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03269318577882065, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": 0.08944815404532412, \"functional effect\": 0.4407, \"times_seen\": 11.0}, {\"site\": 711, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"714\", \"IC90\": null, \"functional effect\": -2.9601, \"times_seen\": null}, {\"site\": 712, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 712, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005311207293662561, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08712261856069092, \"functional effect\": -2.8988, \"times_seen\": 2.0}, {\"site\": 712, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 712, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004301515894823037, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08718361395180277, \"functional effect\": -2.9818, \"times_seen\": 1.0}, {\"site\": 712, \"mutant\": \"S\", \"log2 fold change IC90\": 0.012355559985995019, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08819605243544723, \"functional effect\": -2.0135, \"times_seen\": 10.0}, {\"site\": 712, \"mutant\": \"T\", \"log2 fold change IC90\": 0.002635377580714635, \"epitope\": \"all\", \"reference_site\": \"715\", \"IC90\": 0.08760382733394201, \"functional effect\": -2.5409, \"times_seen\": 1.0}, {\"site\": 713, \"mutant\": \"*\", \"log2 fold change IC90\": -0.003367019769184335, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08724010485220896, \"functional effect\": -2.766, \"times_seen\": 3.0}, {\"site\": 713, \"mutant\": \"A\", \"log2 fold change IC90\": -0.005922527071987552, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08708570951481162, \"functional effect\": -1.3536, \"times_seen\": 42.0}, {\"site\": 713, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0889616364672087, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08221472941554213, \"functional effect\": -0.1522, \"times_seen\": 28.0}, {\"site\": 713, \"mutant\": \"D\", \"log2 fold change IC90\": -0.009096918575936854, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08689430369538317, \"functional effect\": -2.9938, \"times_seen\": 2.0}, {\"site\": 713, \"mutant\": \"E\", \"log2 fold change IC90\": -0.027304633819849638, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08580453439520258, \"functional effect\": -0.7254, \"times_seen\": 7.0}, {\"site\": 713, \"mutant\": \"F\", \"log2 fold change IC90\": 0.007657097267418911, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08790928924999311, \"functional effect\": -1.8224, \"times_seen\": 9.0}, {\"site\": 713, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03934518413809026, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.085091400606497, \"functional effect\": -1.142, \"times_seen\": 27.0}, {\"site\": 713, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0868195046834205, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08233689355518657, \"functional effect\": -0.9137, \"times_seen\": 22.0}, {\"site\": 713, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06195293458674195, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.09128080142888956, \"functional effect\": -2.3512, \"times_seen\": 32.0}, {\"site\": 713, \"mutant\": \"K\", \"log2 fold change IC90\": -0.04288584226772557, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08488282557621077, \"functional effect\": -0.6421, \"times_seen\": 12.0}, {\"site\": 713, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07707275469712459, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08289503930609471, \"functional effect\": 0.1647, \"times_seen\": 50.0}, {\"site\": 713, \"mutant\": \"M\", \"log2 fold change IC90\": -0.029580394576663678, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.085669289832762, \"functional effect\": 0.1258, \"times_seen\": 8.0}, {\"site\": 713, \"mutant\": \"N\", \"log2 fold change IC90\": 0.029866070982657096, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08927304247875124, \"functional effect\": -1.3337, \"times_seen\": 16.0}, {\"site\": 713, \"mutant\": \"P\", \"log2 fold change IC90\": -0.015303860780022696, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08652125925919674, \"functional effect\": -2.6193, \"times_seen\": 2.0}, {\"site\": 713, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02497969930084851, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08594292175067673, \"functional effect\": -0.5219, \"times_seen\": 19.0}, {\"site\": 713, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0034574796758204615, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08765376152758791, \"functional effect\": -0.2702, \"times_seen\": 54.0}, {\"site\": 713, \"mutant\": \"S\", \"log2 fold change IC90\": 0.4573521872348378, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.12006225051648929, \"functional effect\": -0.3731, \"times_seen\": 75.0}, {\"site\": 713, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 713, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0871240636615404, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.09288737916061265, \"functional effect\": -2.65, \"times_seen\": 12.0}, {\"site\": 713, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": null, \"functional effect\": -2.874, \"times_seen\": null}, {\"site\": 713, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01229903657518404, \"epitope\": \"all\", \"reference_site\": \"716\", \"IC90\": 0.08670165227174845, \"functional effect\": -2.5844, \"times_seen\": 3.0}, {\"site\": 714, \"mutant\": \"D\", \"log2 fold change IC90\": -0.013666309815328563, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08661952216825862, \"functional effect\": -2.3437, \"times_seen\": 4.0}, {\"site\": 714, \"mutant\": \"H\", \"log2 fold change IC90\": 0.017582922833614633, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08851619564087965, \"functional effect\": -2.098, \"times_seen\": 7.0}, {\"site\": 714, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": null, \"functional effect\": -1.1916, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"K\", \"log2 fold change IC90\": -0.015484791927910684, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08651040914276305, \"functional effect\": -2.5413, \"times_seen\": 6.0}, {\"site\": 714, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": null, \"functional effect\": -3.1123, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"S\", \"log2 fold change IC90\": -0.041901431999761485, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08494076439019468, \"functional effect\": -1.7257, \"times_seen\": 18.0}, {\"site\": 714, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": null, \"functional effect\": -2.0513, \"times_seen\": null}, {\"site\": 714, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.007441717377292499, \"epitope\": \"all\", \"reference_site\": \"717\", \"IC90\": 0.08789616625499182, \"functional effect\": -1.0141, \"times_seen\": 7.0}, {\"site\": 715, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": null, \"functional effect\": -2.8163, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": null, \"functional effect\": -3.1152, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02258630009842967, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": 0.08882370954203471, \"functional effect\": -2.6831, \"times_seen\": 1.0}, {\"site\": 715, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": null, \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 715, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00758651525342147, \"epitope\": \"all\", \"reference_site\": \"718\", \"IC90\": 0.08698532374313037, \"functional effect\": -2.4214, \"times_seen\": 1.0}, {\"site\": 716, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": null, \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 716, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0038629807734927952, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.08721011912931415, \"functional effect\": -2.2291, \"times_seen\": 2.0}, {\"site\": 716, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04426814313433901, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.084801535069839, \"functional effect\": -2.5731, \"times_seen\": 9.0}, {\"site\": 716, \"mutant\": \"N\", \"log2 fold change IC90\": 0.036558533688302676, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.08968812979432828, \"functional effect\": -1.5682, \"times_seen\": 12.0}, {\"site\": 716, \"mutant\": \"S\", \"log2 fold change IC90\": 0.09343648699737135, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.09329469260741168, \"functional effect\": -0.1762, \"times_seen\": 47.0}, {\"site\": 716, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"719\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": null, \"functional effect\": -1.5184, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00031502415117519493, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.08746304327544796, \"functional effect\": -1.3054, \"times_seen\": 1.0}, {\"site\": 717, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": null, \"functional effect\": -2.6514, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": null, \"functional effect\": -3.0739, \"times_seen\": null}, {\"site\": 717, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003931300443288644, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.08720598934075946, \"functional effect\": -1.6882, \"times_seen\": 1.0}, {\"site\": 717, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0433609037873395, \"epitope\": \"all\", \"reference_site\": \"720\", \"IC90\": 0.0901120117673732, \"functional effect\": -1.9977, \"times_seen\": 5.0}, {\"site\": 718, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -0.8913, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -0.482, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0104457490338026, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08807937750138564, \"functional effect\": -1.3676, \"times_seen\": 4.0}, {\"site\": 718, \"mutant\": \"G\", \"log2 fold change IC90\": -0.008043374963307594, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08695778237295838, \"functional effect\": -0.8207, \"times_seen\": 2.0}, {\"site\": 718, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005021003240246373, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08714014539722126, \"functional effect\": -2.3019, \"times_seen\": 1.0}, {\"site\": 718, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -1.6494, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"P\", \"log2 fold change IC90\": -0.00928523661767092, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08688296193798192, \"functional effect\": -2.8793, \"times_seen\": 2.0}, {\"site\": 718, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": null, \"functional effect\": -0.2213, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 718, \"mutant\": \"T\", \"log2 fold change IC90\": 0.01134819235179156, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.0881344906812976, \"functional effect\": 0.397, \"times_seen\": 3.0}, {\"site\": 718, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004215544878801754, \"epitope\": \"all\", \"reference_site\": \"721\", \"IC90\": 0.08718880942762222, \"functional effect\": -1.6519, \"times_seen\": 3.0}, {\"site\": 719, \"mutant\": \"A\", \"log2 fold change IC90\": 0.002281247349198451, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.08758232635449233, \"functional effect\": -1.1452, \"times_seen\": 1.0}, {\"site\": 719, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": null, \"functional effect\": -1.8183, \"times_seen\": null}, {\"site\": 719, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": null, \"functional effect\": -2.9973, \"times_seen\": null}, {\"site\": 719, \"mutant\": \"F\", \"log2 fold change IC90\": 0.002859436014024879, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.08761743374418401, \"functional effect\": -2.3651, \"times_seen\": 1.0}, {\"site\": 719, \"mutant\": \"I\", \"log2 fold change IC90\": 1.0483507435296484, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.1808484423804286, \"functional effect\": -0.1681, \"times_seen\": 7.0}, {\"site\": 719, \"mutant\": \"L\", \"log2 fold change IC90\": 0.004092445755845326, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.08769234862578222, \"functional effect\": -1.12, \"times_seen\": 1.0}, {\"site\": 719, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01576397905028203, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.0864936694613528, \"functional effect\": -0.9729, \"times_seen\": 5.0}, {\"site\": 719, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": null, \"functional effect\": -2.8552, \"times_seen\": null}, {\"site\": 719, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"722\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 720, \"mutant\": \"A\", \"log2 fold change IC90\": -0.035274278911285595, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08533184519183709, \"functional effect\": 0.1971, \"times_seen\": 5.0}, {\"site\": 720, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06495730095584394, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08359410585351341, \"functional effect\": -0.552, \"times_seen\": 21.0}, {\"site\": 720, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005181421755137274, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08713045650583212, \"functional effect\": 0.3561, \"times_seen\": 4.0}, {\"site\": 720, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005224715177248718, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08712784187215913, \"functional effect\": -1.8336, \"times_seen\": 1.0}, {\"site\": 720, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": null, \"functional effect\": -0.2352, \"times_seen\": null}, {\"site\": 720, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 720, \"mutant\": \"V\", \"log2 fold change IC90\": -0.006922351895533531, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08702537778314487, \"functional effect\": -0.1125, \"times_seen\": 2.0}, {\"site\": 720, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005472698499492952, \"epitope\": \"all\", \"reference_site\": \"723\", \"IC90\": 0.08711286684677702, \"functional effect\": -1.4441, \"times_seen\": 1.0}, {\"site\": 721, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02443211567438327, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08893742526759463, \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 721, \"mutant\": \"I\", \"log2 fold change IC90\": 0.17480812928541575, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.09870797518236193, \"functional effect\": -0.3543, \"times_seen\": 22.0}, {\"site\": 721, \"mutant\": \"K\", \"log2 fold change IC90\": -0.010051693618043261, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08683681610221046, \"functional effect\": 0.106, \"times_seen\": 2.0}, {\"site\": 721, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0006626431794406603, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08748412013539578, \"functional effect\": -0.394, \"times_seen\": 1.0}, {\"site\": 721, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0007310171340595366, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.08739965025631222, \"functional effect\": -0.3071, \"times_seen\": 16.0}, {\"site\": 721, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"724\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -2.9082, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"D\", \"log2 fold change IC90\": -0.025342653567743238, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": 0.08592130288752062, \"functional effect\": 0.0546, \"times_seen\": 4.0}, {\"site\": 722, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -3.0518, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -3.1332, \"times_seen\": null}, {\"site\": 722, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"725\", \"IC90\": null, \"functional effect\": -2.8455, \"times_seen\": null}, {\"site\": 723, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 723, \"mutant\": \"K\", \"log2 fold change IC90\": 0.005174390612454511, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.08775813790806913, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 723, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": null, \"functional effect\": -2.682, \"times_seen\": null}, {\"site\": 723, \"mutant\": \"T\", \"log2 fold change IC90\": 0.4861460107651582, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.12248256828895322, \"functional effect\": 0.3018, \"times_seen\": 8.0}, {\"site\": 723, \"mutant\": \"V\", \"log2 fold change IC90\": 0.011924288693024346, \"epitope\": \"all\", \"reference_site\": \"726\", \"IC90\": 0.08816969153459309, \"functional effect\": -0.9196, \"times_seen\": 4.0}, {\"site\": 724, \"mutant\": \"I\", \"log2 fold change IC90\": 0.031452182658542945, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08937124402241733, \"functional effect\": 0.0311, \"times_seen\": 4.0}, {\"site\": 724, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 724, \"mutant\": \"M\", \"log2 fold change IC90\": -0.022292116048119197, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08610317324415921, \"functional effect\": -0.4216, \"times_seen\": 5.0}, {\"site\": 724, \"mutant\": \"P\", \"log2 fold change IC90\": -0.006990749671380734, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.08702125203167509, \"functional effect\": -2.1136, \"times_seen\": 2.0}, {\"site\": 724, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.07082185627080935, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.09184367559298276, \"functional effect\": -1.2101, \"times_seen\": 4.0}, {\"site\": 724, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0014264073670529447, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": 0.0873575330961877, \"functional effect\": -0.4228, \"times_seen\": 1.0}, {\"site\": 724, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"727\", \"IC90\": null, \"functional effect\": -2.2196, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -2.4798, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"L\", \"log2 fold change IC90\": -0.032979254498938106, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": 0.08546769824047899, \"functional effect\": -2.5579, \"times_seen\": 2.0}, {\"site\": 725, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -2.37, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -1.6758, \"times_seen\": null}, {\"site\": 725, \"mutant\": \"S\", \"log2 fold change IC90\": 0.014157307432478698, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": 0.08830626719093564, \"functional effect\": -1.3273, \"times_seen\": 19.0}, {\"site\": 725, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"728\", \"IC90\": null, \"functional effect\": -0.7129, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01649192834305924, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.08645003784026124, \"functional effect\": 0.3624, \"times_seen\": 1.0}, {\"site\": 726, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": null, \"functional effect\": -2.3628, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"E\", \"log2 fold change IC90\": -0.016710046065324082, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.08643696864721502, \"functional effect\": -2.8092, \"times_seen\": 1.0}, {\"site\": 726, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": null, \"functional effect\": -2.8622, \"times_seen\": null}, {\"site\": 726, \"mutant\": \"M\", \"log2 fold change IC90\": -0.6055681981938543, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.057469254144259956, \"functional effect\": -2.6593, \"times_seen\": 4.0}, {\"site\": 726, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"729\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": 0.4189, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"C\", \"log2 fold change IC90\": -0.003910158586190316, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08720726730319901, \"functional effect\": -0.3591, \"times_seen\": 1.0}, {\"site\": 727, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03419416146962383, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08539575538952993, \"functional effect\": -0.2728, \"times_seen\": 20.0}, {\"site\": 727, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0013488318845194531, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08752574008406562, \"functional effect\": -3.0775, \"times_seen\": 2.0}, {\"site\": 727, \"mutant\": \"I\", \"log2 fold change IC90\": 0.025837637163422175, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.0890241132854313, \"functional effect\": -0.6208, \"times_seen\": 2.0}, {\"site\": 727, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -2.1244, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0009223526750536426, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08749987017350248, \"functional effect\": -2.1699, \"times_seen\": 3.0}, {\"site\": 727, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -1.0604, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005123816818239035, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08713393558111274, \"functional effect\": -1.1008, \"times_seen\": 1.0}, {\"site\": 727, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 727, \"mutant\": \"T\", \"log2 fold change IC90\": 0.008465321341885212, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": 0.08795855143466129, \"functional effect\": -0.5495, \"times_seen\": 2.0}, {\"site\": 727, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"730\", \"IC90\": null, \"functional effect\": -2.4419, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": null, \"functional effect\": -2.3264, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"I\", \"log2 fold change IC90\": -0.3084269839075183, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.07061288883017085, \"functional effect\": -1.1321, \"times_seen\": 36.0}, {\"site\": 728, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": null, \"functional effect\": -2.606, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"L\", \"log2 fold change IC90\": 1.0729483201443923, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.18395829723691734, \"functional effect\": -0.5081, \"times_seen\": 6.0}, {\"site\": 728, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 728, \"mutant\": \"T\", \"log2 fold change IC90\": 0.002354885921278903, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.08758679687797061, \"functional effect\": -2.2466, \"times_seen\": 5.0}, {\"site\": 728, \"mutant\": \"V\", \"log2 fold change IC90\": 0.018404175472285674, \"epitope\": \"all\", \"reference_site\": \"731\", \"IC90\": 0.08856659773670575, \"functional effect\": -1.9343, \"times_seen\": 7.0}, {\"site\": 729, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 729, \"mutant\": \"A\", \"log2 fold change IC90\": -0.018129728891686507, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.08635195225884175, \"functional effect\": 0.2513, \"times_seen\": 37.0}, {\"site\": 729, \"mutant\": \"I\", \"log2 fold change IC90\": 0.15349578936179797, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.09726052054889413, \"functional effect\": 0.2091, \"times_seen\": 44.0}, {\"site\": 729, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 729, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": null, \"functional effect\": -2.9597, \"times_seen\": null}, {\"site\": 729, \"mutant\": \"P\", \"log2 fold change IC90\": -0.017552388550140893, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.08638651565647841, \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 729, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06650828907232313, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.08350428521002477, \"functional effect\": 0.2056, \"times_seen\": 32.0}, {\"site\": 729, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"732\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0050151519812902945, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.08714049881951476, \"functional effect\": -2.8693, \"times_seen\": 1.0}, {\"site\": 730, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": null, \"functional effect\": -3.1325, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": null, \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 730, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010063099972062582, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.08683612954855723, \"functional effect\": -2.9305, \"times_seen\": 1.0}, {\"site\": 730, \"mutant\": \"R\", \"log2 fold change IC90\": -0.19064592129093907, \"epitope\": \"all\", \"reference_site\": \"733\", \"IC90\": 0.07661955264580499, \"functional effect\": -0.7708, \"times_seen\": 18.0}, {\"site\": 731, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 731, \"mutant\": \"A\", \"log2 fold change IC90\": -0.05042872811996298, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08444018828276356, \"functional effect\": -0.4737, \"times_seen\": 13.0}, {\"site\": 731, \"mutant\": \"H\", \"log2 fold change IC90\": -0.017207579368420566, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08640716480463306, \"functional effect\": -0.9347, \"times_seen\": 4.0}, {\"site\": 731, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02109934057819088, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08873220772401416, \"functional effect\": 0.2248, \"times_seen\": 32.0}, {\"site\": 731, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": null, \"functional effect\": -2.9745, \"times_seen\": null}, {\"site\": 731, \"mutant\": \"N\", \"log2 fold change IC90\": -0.01113159905211938, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.0867718401657724, \"functional effect\": -2.7603, \"times_seen\": 2.0}, {\"site\": 731, \"mutant\": \"S\", \"log2 fold change IC90\": -0.007297085039323258, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.08700277629250765, \"functional effect\": -1.162, \"times_seen\": 1.0}, {\"site\": 731, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"734\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": null, \"functional effect\": -1.7772, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"A\", \"log2 fold change IC90\": -0.10619333127501267, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08123858957171315, \"functional effect\": -0.0825, \"times_seen\": 28.0}, {\"site\": 732, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03018826054115507, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08563320148781915, \"functional effect\": -0.7428, \"times_seen\": 6.0}, {\"site\": 732, \"mutant\": \"I\", \"log2 fold change IC90\": -0.00937557414537601, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08687752174027613, \"functional effect\": -1.1909, \"times_seen\": 3.0}, {\"site\": 732, \"mutant\": \"L\", \"log2 fold change IC90\": 0.19200173977494975, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.09989138523602034, \"functional effect\": -1.0983, \"times_seen\": 20.0}, {\"site\": 732, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": null, \"functional effect\": -2.7322, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012023907114267764, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08671818830526672, \"functional effect\": -0.2029, \"times_seen\": 5.0}, {\"site\": 732, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": null, \"functional effect\": 0.6738, \"times_seen\": null}, {\"site\": 732, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.014291114245703208, \"epitope\": \"all\", \"reference_site\": \"735\", \"IC90\": 0.08658201698377702, \"functional effect\": -0.4477, \"times_seen\": 3.0}, {\"site\": 733, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": null, \"functional effect\": -1.6969, \"times_seen\": null}, {\"site\": 733, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02248585501846707, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.08609161125799683, \"functional effect\": -0.0938, \"times_seen\": 9.0}, {\"site\": 733, \"mutant\": \"L\", \"log2 fold change IC90\": 0.006920548502837619, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.0878644197863313, \"functional effect\": -1.4082, \"times_seen\": 4.0}, {\"site\": 733, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0076251737738969845, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.08698299291175558, \"functional effect\": -1.4028, \"times_seen\": 4.0}, {\"site\": 733, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 733, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"736\", \"IC90\": null, \"functional effect\": -2.9548, \"times_seen\": null}, {\"site\": 734, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 734, \"mutant\": \"E\", \"log2 fold change IC90\": -0.032317365917535174, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08550691863752374, \"functional effect\": -1.017, \"times_seen\": 20.0}, {\"site\": 734, \"mutant\": \"G\", \"log2 fold change IC90\": -0.018284389615993837, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08634269559733711, \"functional effect\": -1.6831, \"times_seen\": 5.0}, {\"site\": 734, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0007511341266891616, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08739843156087629, \"functional effect\": -1.036, \"times_seen\": 1.0}, {\"site\": 734, \"mutant\": \"N\", \"log2 fold change IC90\": -0.026509288017865333, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.0858518507642179, \"functional effect\": -2.4426, \"times_seen\": 5.0}, {\"site\": 734, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.10742038466451372, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.09420338548236416, \"functional effect\": -1.5423, \"times_seen\": 4.0}, {\"site\": 734, \"mutant\": \"V\", \"log2 fold change IC90\": -0.018507761388657628, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.0863293282345603, \"functional effect\": -1.4984, \"times_seen\": 5.0}, {\"site\": 734, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004336940246413706, \"epitope\": \"all\", \"reference_site\": \"737\", \"IC90\": 0.08718147324639425, \"functional effect\": -0.4777, \"times_seen\": 7.0}, {\"site\": 735, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": null, \"functional effect\": -2.9813, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"F\", \"log2 fold change IC90\": 0.004878703129061293, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": 0.08774015328678368, \"functional effect\": -2.5456, \"times_seen\": 4.0}, {\"site\": 735, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": null, \"functional effect\": -2.9196, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 735, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02224677502962946, \"epitope\": \"all\", \"reference_site\": \"738\", \"IC90\": 0.08610587933713633, \"functional effect\": -2.4725, \"times_seen\": 4.0}, {\"site\": 736, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01662600460203474, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08644200401554258, \"functional effect\": 0.0824, \"times_seen\": 6.0}, {\"site\": 736, \"mutant\": \"I\", \"log2 fold change IC90\": -0.23001770087084436, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.07455684560163606, \"functional effect\": -0.1671, \"times_seen\": 39.0}, {\"site\": 736, \"mutant\": \"K\", \"log2 fold change IC90\": -0.006834818925504923, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08703065805421109, \"functional effect\": -0.4855, \"times_seen\": 1.0}, {\"site\": 736, \"mutant\": \"L\", \"log2 fold change IC90\": 0.012743771446972743, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.08821978809989452, \"functional effect\": -0.0817, \"times_seen\": 3.0}, {\"site\": 736, \"mutant\": \"S\", \"log2 fold change IC90\": -0.006164453646239436, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.087071107273598, \"functional effect\": -0.0087, \"times_seen\": 5.0}, {\"site\": 736, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"739\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 737, \"mutant\": \"F\", \"log2 fold change IC90\": 0.001854621689347686, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08755643083077198, \"functional effect\": -0.2664, \"times_seen\": 3.0}, {\"site\": 737, \"mutant\": \"I\", \"log2 fold change IC90\": 0.05089523134286735, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.09058384352283243, \"functional effect\": -0.4403, \"times_seen\": 25.0}, {\"site\": 737, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0037296956271529874, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.0872181765150524, \"functional effect\": -0.0781, \"times_seen\": 4.0}, {\"site\": 737, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03685770553453741, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.0852382407984898, \"functional effect\": -0.9326, \"times_seen\": 6.0}, {\"site\": 737, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 737, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 737, \"mutant\": \"S\", \"log2 fold change IC90\": -1.1853296757889116, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.0384512059922468, \"functional effect\": -0.3955, \"times_seen\": 2.0}, {\"site\": 737, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00031844345501608917, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08742464788274525, \"functional effect\": -0.0225, \"times_seen\": 6.0}, {\"site\": 737, \"mutant\": \"V\", \"log2 fold change IC90\": -0.028156765682165536, \"epitope\": \"all\", \"reference_site\": \"740\", \"IC90\": 0.08575386867129436, \"functional effect\": -0.2248, \"times_seen\": 8.0}, {\"site\": 738, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": -2.5015, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": null, \"functional effect\": -1.5617, \"times_seen\": null}, {\"site\": 738, \"mutant\": \"H\", \"log2 fold change IC90\": -0.011270513461525097, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.08676348546967592, \"functional effect\": -2.7764, \"times_seen\": 2.0}, {\"site\": 738, \"mutant\": \"N\", \"log2 fold change IC90\": -0.003508564775096066, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.08723154601262978, \"functional effect\": -2.4574, \"times_seen\": 1.0}, {\"site\": 738, \"mutant\": \"V\", \"log2 fold change IC90\": 0.014094251713951506, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.08830240768266297, \"functional effect\": -2.8876, \"times_seen\": 4.0}, {\"site\": 738, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"741\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"L\", \"log2 fold change IC90\": -1.1801501529089138, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.03858950052511135, \"functional effect\": -0.1766, \"times_seen\": 6.0}, {\"site\": 739, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -3.0936, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": null, \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 739, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03548401960944237, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.08531944044976952, \"functional effect\": 0.1886, \"times_seen\": 6.0}, {\"site\": 739, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027666157024074503, \"epitope\": \"all\", \"reference_site\": \"742\", \"IC90\": 0.08578303543458815, \"functional effect\": -2.1587, \"times_seen\": 1.0}, {\"site\": 740, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -0.6647, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -3.0343, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -2.8525, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -3.0053, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"R\", \"log2 fold change IC90\": -0.020865216989903197, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": 0.08618837580674898, \"functional effect\": -2.6612, \"times_seen\": 4.0}, {\"site\": 740, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -3.052, \"times_seen\": null}, {\"site\": 740, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"743\", \"IC90\": null, \"functional effect\": -2.6502, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": null, \"functional effect\": -2.6347, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": null, \"functional effect\": 0.4254, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"D\", \"log2 fold change IC90\": -0.11279690196570408, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08086759025496115, \"functional effect\": -1.9342, \"times_seen\": 3.0}, {\"site\": 741, \"mutant\": \"E\", \"log2 fold change IC90\": 0.02672745625258878, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08907903812209032, \"functional effect\": -0.6324, \"times_seen\": 12.0}, {\"site\": 741, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 741, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.04343508333794294, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08485051641916753, \"functional effect\": -0.8634, \"times_seen\": 10.0}, {\"site\": 741, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03629623883923746, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08527142019259308, \"functional effect\": -1.8853, \"times_seen\": 8.0}, {\"site\": 741, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005485728629166612, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08711208006454436, \"functional effect\": -0.4687, \"times_seen\": 1.0}, {\"site\": 741, \"mutant\": \"V\", \"log2 fold change IC90\": 0.011788871524130475, \"epitope\": \"all\", \"reference_site\": \"744\", \"IC90\": 0.08816141596052145, \"functional effect\": -2.1101, \"times_seen\": 2.0}, {\"site\": 742, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 742, \"mutant\": \"A\", \"log2 fold change IC90\": -0.014282016815627201, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08658256295940354, \"functional effect\": -0.381, \"times_seen\": 4.0}, {\"site\": 742, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 742, \"mutant\": \"E\", \"log2 fold change IC90\": -0.037480620213122234, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08520144529506647, \"functional effect\": -1.2556, \"times_seen\": 9.0}, {\"site\": 742, \"mutant\": \"G\", \"log2 fold change IC90\": -0.017301111050544223, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08640156310415473, \"functional effect\": -0.5194, \"times_seen\": 11.0}, {\"site\": 742, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": null, \"functional effect\": -1.1698, \"times_seen\": null}, {\"site\": 742, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004245256202867228, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08718701385182567, \"functional effect\": -2.9882, \"times_seen\": 1.0}, {\"site\": 742, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.015589685934670071, \"epitope\": \"all\", \"reference_site\": \"745\", \"IC90\": 0.08839398552896383, \"functional effect\": -0.4782, \"times_seen\": 4.0}, {\"site\": 743, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 743, \"mutant\": \"C\", \"log2 fold change IC90\": -0.008154601575019444, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08695107849834055, \"functional effect\": 0.0849, \"times_seen\": 2.0}, {\"site\": 743, \"mutant\": \"G\", \"log2 fold change IC90\": 0.031985034726399277, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08940425893293169, \"functional effect\": -2.1692, \"times_seen\": 3.0}, {\"site\": 743, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04697737181521364, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08464243618933431, \"functional effect\": -0.953, \"times_seen\": 10.0}, {\"site\": 743, \"mutant\": \"N\", \"log2 fold change IC90\": 0.2637670574315816, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.1049860386058428, \"functional effect\": -0.334, \"times_seen\": 31.0}, {\"site\": 743, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004113256710935576, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08719499139920288, \"functional effect\": -2.1849, \"times_seen\": 1.0}, {\"site\": 743, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 743, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003884271943912314, \"epitope\": \"all\", \"reference_site\": \"746\", \"IC90\": 0.08720883209930791, \"functional effect\": -0.7858, \"times_seen\": 1.0}, {\"site\": 744, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 744, \"mutant\": \"A\", \"log2 fold change IC90\": -0.017230352352458123, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08640580087573704, \"functional effect\": 0.3931, \"times_seen\": 11.0}, {\"site\": 744, \"mutant\": \"I\", \"log2 fold change IC90\": 1.1474244312234831, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.19370414957690116, \"functional effect\": -0.2878, \"times_seen\": 22.0}, {\"site\": 744, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0030578812894088564, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08725880053098976, \"functional effect\": 0.1667, \"times_seen\": 2.0}, {\"site\": 744, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0010600292813364332, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08737972070285152, \"functional effect\": -0.1635, \"times_seen\": 3.0}, {\"site\": 744, \"mutant\": \"P\", \"log2 fold change IC90\": 0.015009090352320321, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.0883584195703666, \"functional effect\": -0.0825, \"times_seen\": 4.0}, {\"site\": 744, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01956269726637642, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08863774759139424, \"functional effect\": 0.3651, \"times_seen\": 5.0}, {\"site\": 744, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 744, \"mutant\": \"V\", \"log2 fold change IC90\": -0.014719335790574497, \"epitope\": \"all\", \"reference_site\": \"747\", \"IC90\": 0.08655632147498077, \"functional effect\": -0.047, \"times_seen\": 4.0}, {\"site\": 745, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -2.9623, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -1.1213, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -0.4818, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"D\", \"log2 fold change IC90\": 0.07235497140197593, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.09194132739549876, \"functional effect\": -0.1863, \"times_seen\": 8.0}, {\"site\": 745, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": null, \"functional effect\": -0.1913, \"times_seen\": null}, {\"site\": 745, \"mutant\": \"K\", \"log2 fold change IC90\": 1.8071680103942416, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.30601416590185476, \"functional effect\": -0.4162, \"times_seen\": 12.0}, {\"site\": 745, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.1055601253319611, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.09408199475968133, \"functional effect\": -0.5398, \"times_seen\": 13.0}, {\"site\": 745, \"mutant\": \"R\", \"log2 fold change IC90\": 0.007097332724862036, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.0878751871310467, \"functional effect\": -0.8477, \"times_seen\": 5.0}, {\"site\": 745, \"mutant\": \"V\", \"log2 fold change IC90\": 0.02389128259634039, \"epitope\": \"all\", \"reference_site\": \"748\", \"IC90\": 0.08890409092778083, \"functional effect\": -0.5605, \"times_seen\": 11.0}, {\"site\": 746, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -3.0745, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0027064302474375987, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.08728006000106367, \"functional effect\": -2.2959, \"times_seen\": 1.0}, {\"site\": 746, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -2.9607, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0006513355288374948, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.08740447756669524, \"functional effect\": -3.1098, \"times_seen\": 1.0}, {\"site\": 746, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -3.0024, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -2.8875, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": null, \"functional effect\": -3.0069, \"times_seen\": null}, {\"site\": 746, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01863167244486724, \"epitope\": \"all\", \"reference_site\": \"749\", \"IC90\": 0.08858056480595952, \"functional effect\": -2.3491, \"times_seen\": 5.0}, {\"site\": 747, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 747, \"mutant\": \"C\", \"log2 fold change IC90\": -0.013478178432363961, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08663081832759466, \"functional effect\": -1.0003, \"times_seen\": 13.0}, {\"site\": 747, \"mutant\": \"G\", \"log2 fold change IC90\": 0.07152522705575053, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.09188846392765193, \"functional effect\": 0.2269, \"times_seen\": 79.0}, {\"site\": 747, \"mutant\": \"I\", \"log2 fold change IC90\": -0.08397812082146315, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08249921563152342, \"functional effect\": -0.3044, \"times_seen\": 16.0}, {\"site\": 747, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03722306053974512, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08521665739100663, \"functional effect\": -0.0421, \"times_seen\": 31.0}, {\"site\": 747, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03851322418350033, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08514048447503589, \"functional effect\": -0.1217, \"times_seen\": 13.0}, {\"site\": 747, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 747, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00872951409272379, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08691643548437884, \"functional effect\": 0.0836, \"times_seen\": 20.0}, {\"site\": 747, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.029363486726601867, \"epitope\": \"all\", \"reference_site\": \"750\", \"IC90\": 0.08568217109868174, \"functional effect\": -0.0658, \"times_seen\": 14.0}, {\"site\": 748, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 748, \"mutant\": \"D\", \"log2 fold change IC90\": -0.3798592034444089, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.0672017741080234, \"functional effect\": 0.0264, \"times_seen\": 44.0}, {\"site\": 748, \"mutant\": \"F\", \"log2 fold change IC90\": 0.029336118747378605, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08924025539711194, \"functional effect\": -0.0541, \"times_seen\": 2.0}, {\"site\": 748, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03395130976878857, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08952619268084756, \"functional effect\": -0.2394, \"times_seen\": 5.0}, {\"site\": 748, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03903799744534263, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.0898424033337769, \"functional effect\": 0.2424, \"times_seen\": 9.0}, {\"site\": 748, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 748, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008621141424110598, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08692296473663565, \"functional effect\": 0.0683, \"times_seen\": 7.0}, {\"site\": 748, \"mutant\": \"T\", \"log2 fold change IC90\": 0.01624256453862729, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08843399648096441, \"functional effect\": 0.0901, \"times_seen\": 9.0}, {\"site\": 748, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03748533697726936, \"epitope\": \"all\", \"reference_site\": \"751\", \"IC90\": 0.08520116673691377, \"functional effect\": 0.0153, \"times_seen\": 5.0}, {\"site\": 749, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 749, \"mutant\": \"F\", \"log2 fold change IC90\": -0.019951872460641507, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08624295740755199, \"functional effect\": -2.0375, \"times_seen\": 6.0}, {\"site\": 749, \"mutant\": \"I\", \"log2 fold change IC90\": 0.012199561811161308, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08818651633876894, \"functional effect\": -1.0664, \"times_seen\": 3.0}, {\"site\": 749, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 749, \"mutant\": \"M\", \"log2 fold change IC90\": 0.004743953526390072, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08773195862447718, \"functional effect\": -0.0729, \"times_seen\": 12.0}, {\"site\": 749, \"mutant\": \"P\", \"log2 fold change IC90\": -0.7189778340435857, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.05312462269047747, \"functional effect\": -2.6643, \"times_seen\": 10.0}, {\"site\": 749, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013958666443928892, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08660197083201428, \"functional effect\": -0.3644, \"times_seen\": 2.0}, {\"site\": 749, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": null, \"functional effect\": -0.0322, \"times_seen\": null}, {\"site\": 749, \"mutant\": \"V\", \"log2 fold change IC90\": -0.015459998691392531, \"epitope\": \"all\", \"reference_site\": \"752\", \"IC90\": 0.08651189586823495, \"functional effect\": -0.776, \"times_seen\": 6.0}, {\"site\": 750, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 750, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": null, \"functional effect\": -2.9731, \"times_seen\": null}, {\"site\": 750, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02670009864373329, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08907734894571755, \"functional effect\": -0.7661, \"times_seen\": 6.0}, {\"site\": 750, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 750, \"mutant\": \"M\", \"log2 fold change IC90\": 0.024406753536817705, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08893586178860302, \"functional effect\": -0.673, \"times_seen\": 2.0}, {\"site\": 750, \"mutant\": \"P\", \"log2 fold change IC90\": 0.032321167702452996, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08942509162446838, \"functional effect\": -2.7073, \"times_seen\": 2.0}, {\"site\": 750, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.012771083670550997, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08667328829528274, \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 750, \"mutant\": \"V\", \"log2 fold change IC90\": -0.026544570368831302, \"epitope\": \"all\", \"reference_site\": \"753\", \"IC90\": 0.08584975120886829, \"functional effect\": -0.3226, \"times_seen\": 12.0}, {\"site\": 751, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 751, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005038015622025375, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.087139117839325, \"functional effect\": -0.4671, \"times_seen\": 1.0}, {\"site\": 751, \"mutant\": \"F\", \"log2 fold change IC90\": 0.04000881711499617, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08990288051209752, \"functional effect\": 0.0366, \"times_seen\": 76.0}, {\"site\": 751, \"mutant\": \"H\", \"log2 fold change IC90\": 0.011125491983134476, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.0881208869270804, \"functional effect\": -2.891, \"times_seen\": 4.0}, {\"site\": 751, \"mutant\": \"I\", \"log2 fold change IC90\": -0.08480078884344858, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.0824521855124131, \"functional effect\": -0.0719, \"times_seen\": 24.0}, {\"site\": 751, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 751, \"mutant\": \"P\", \"log2 fold change IC90\": 0.020741931061075622, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08871022816034917, \"functional effect\": 0.1158, \"times_seen\": 12.0}, {\"site\": 751, \"mutant\": \"S\", \"log2 fold change IC90\": 0.012862865985870003, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08822707094786676, \"functional effect\": 0.0848, \"times_seen\": 5.0}, {\"site\": 751, \"mutant\": \"V\", \"log2 fold change IC90\": -0.030021376694275716, \"epitope\": \"all\", \"reference_site\": \"754\", \"IC90\": 0.08564310768715873, \"functional effect\": 0.1702, \"times_seen\": 8.0}, {\"site\": 752, \"mutant\": \"*\", \"log2 fold change IC90\": -0.004729139677252047, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.08715777601587275, \"functional effect\": -2.2523, \"times_seen\": 1.0}, {\"site\": 752, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -0.8822, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"A\", \"log2 fold change IC90\": -0.013471246098594552, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.08663123460073154, \"functional effect\": -0.2403, \"times_seen\": 2.0}, {\"site\": 752, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -0.6948, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -0.9599, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"K\", \"log2 fold change IC90\": 0.009693644903103406, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.08803347202765552, \"functional effect\": -1.4802, \"times_seen\": 3.0}, {\"site\": 752, \"mutant\": \"N\", \"log2 fold change IC90\": 0.028604283830245096, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.08919499803418793, \"functional effect\": -1.0858, \"times_seen\": 5.0}, {\"site\": 752, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": -3.234, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 752, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"755\", \"IC90\": null, \"functional effect\": 0.4155, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -3.0014, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"A\", \"log2 fold change IC90\": -0.011655363947950253, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08674034370001424, \"functional effect\": -1.943, \"times_seen\": 2.0}, {\"site\": 753, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -1.2583, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -1.0683, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01460343149066523, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08656327558001259, \"functional effect\": -2.4891, \"times_seen\": 6.0}, {\"site\": 753, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0056459945955836845, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08710240350374915, \"functional effect\": -1.4326, \"times_seen\": 1.0}, {\"site\": 753, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -0.7486, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"M\", \"log2 fold change IC90\": -0.003284572156592651, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.08724509062099159, \"functional effect\": -2.9344, \"times_seen\": 1.0}, {\"site\": 753, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": null, \"functional effect\": -3.1031, \"times_seen\": null}, {\"site\": 753, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"756\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 754, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": null, \"functional effect\": -0.6432, \"times_seen\": null}, {\"site\": 754, \"mutant\": \"A\", \"log2 fold change IC90\": -0.048694538845885475, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08454175050560633, \"functional effect\": -1.7854, \"times_seen\": 7.0}, {\"site\": 754, \"mutant\": \"C\", \"log2 fold change IC90\": -0.010490398351950822, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08681041417415011, \"functional effect\": -2.8243, \"times_seen\": 1.0}, {\"site\": 754, \"mutant\": \"D\", \"log2 fold change IC90\": -0.5554981199281558, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.059498793071920984, \"functional effect\": -1.0894, \"times_seen\": 58.0}, {\"site\": 754, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 754, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0037671967585175487, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08721590941237822, \"functional effect\": -1.9744, \"times_seen\": 7.0}, {\"site\": 754, \"mutant\": \"S\", \"log2 fold change IC90\": 0.010321794163001868, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08807181013715659, \"functional effect\": -1.7512, \"times_seen\": 5.0}, {\"site\": 754, \"mutant\": \"V\", \"log2 fold change IC90\": -0.003895218021784454, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08720817042721583, \"functional effect\": -0.6318, \"times_seen\": 4.0}, {\"site\": 754, \"mutant\": \"W\", \"log2 fold change IC90\": 0.031818477037006715, \"epitope\": \"all\", \"reference_site\": \"757\", \"IC90\": 0.08939393789707363, \"functional effect\": -2.4308, \"times_seen\": 7.0}, {\"site\": 755, \"mutant\": \"A\", \"log2 fold change IC90\": -0.024579139784738482, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08596678683210092, \"functional effect\": -0.2737, \"times_seen\": 11.0}, {\"site\": 755, \"mutant\": \"F\", \"log2 fold change IC90\": 0.07926205406683819, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.09238256337494737, \"functional effect\": 0.0587, \"times_seen\": 5.0}, {\"site\": 755, \"mutant\": \"G\", \"log2 fold change IC90\": 0.01722726460179677, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08849437700798142, \"functional effect\": 0.3216, \"times_seen\": 5.0}, {\"site\": 755, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01306833977775558, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08665543177711607, \"functional effect\": -0.1119, \"times_seen\": 7.0}, {\"site\": 755, \"mutant\": \"P\", \"log2 fold change IC90\": -0.04511478797640438, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08475178393228054, \"functional effect\": -0.4627, \"times_seen\": 3.0}, {\"site\": 755, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01192440291265223, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08672416955662247, \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 755, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 755, \"mutant\": \"T\", \"log2 fold change IC90\": 1.5234173482957316, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.25137615008582653, \"functional effect\": 0.1522, \"times_seen\": 15.0}, {\"site\": 755, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02046015911336197, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08621257785977056, \"functional effect\": 0.0004, \"times_seen\": 9.0}, {\"site\": 755, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0008490341763202362, \"epitope\": \"all\", \"reference_site\": \"758\", \"IC90\": 0.08749542349840796, \"functional effect\": -0.2785, \"times_seen\": 1.0}, {\"site\": 756, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0049152622779840656, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08714653248544789, \"functional effect\": -1.9521, \"times_seen\": 1.0}, {\"site\": 756, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 756, \"mutant\": \"I\", \"log2 fold change IC90\": 0.024105003851232508, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08891726218074363, \"functional effect\": -1.2458, \"times_seen\": 7.0}, {\"site\": 756, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010962340481578113, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08678202093079025, \"functional effect\": -1.2885, \"times_seen\": 9.0}, {\"site\": 756, \"mutant\": \"S\", \"log2 fold change IC90\": 0.09774347483230297, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.09357362854514231, \"functional effect\": -1.2136, \"times_seen\": 15.0}, {\"site\": 756, \"mutant\": \"V\", \"log2 fold change IC90\": -0.008956616546896567, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.0869027545734988, \"functional effect\": -1.5576, \"times_seen\": 2.0}, {\"site\": 756, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009867620566919168, \"epitope\": \"all\", \"reference_site\": \"759\", \"IC90\": 0.08684789629379457, \"functional effect\": -0.2353, \"times_seen\": 2.0}, {\"site\": 757, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.4519, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"F\", \"log2 fold change IC90\": -0.005970165551680478, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": 0.08708283395054298, \"functional effect\": -1.2855, \"times_seen\": 1.0}, {\"site\": 757, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.919, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -3.0579, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.6628, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": null, \"functional effect\": -2.8402, \"times_seen\": null}, {\"site\": 757, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04184465335634369, \"epitope\": \"all\", \"reference_site\": \"760\", \"IC90\": 0.08494410738101456, \"functional effect\": -1.6236, \"times_seen\": 5.0}, {\"site\": 758, \"mutant\": \"A\", \"log2 fold change IC90\": -1.1243013343355988, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.040112647495714374, \"functional effect\": 0.1197, \"times_seen\": 47.0}, {\"site\": 758, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01763114315210699, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08638180007225979, \"functional effect\": -1.0763, \"times_seen\": 5.0}, {\"site\": 758, \"mutant\": \"D\", \"log2 fold change IC90\": 0.01128616335558265, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08813070140060421, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 758, \"mutant\": \"I\", \"log2 fold change IC90\": -0.20523537828616664, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.07584863121339937, \"functional effect\": -0.1772, \"times_seen\": 71.0}, {\"site\": 758, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0763141634976473, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.0829386382517861, \"functional effect\": -0.2376, \"times_seen\": 9.0}, {\"site\": 758, \"mutant\": \"N\", \"log2 fold change IC90\": 0.04343553007201959, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.09011667311185735, \"functional effect\": 0.1582, \"times_seen\": 6.0}, {\"site\": 758, \"mutant\": \"R\", \"log2 fold change IC90\": -0.025379726500188528, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08591909499628886, \"functional effect\": -0.1127, \"times_seen\": 10.0}, {\"site\": 758, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004273562369088467, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08718530322981213, \"functional effect\": -0.0003, \"times_seen\": 5.0}, {\"site\": 758, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 758, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.006189574397397138, \"epitope\": \"all\", \"reference_site\": \"761\", \"IC90\": 0.08781991256502208, \"functional effect\": -0.115, \"times_seen\": 15.0}, {\"site\": 759, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": null, \"functional effect\": -1.8736, \"times_seen\": null}, {\"site\": 759, \"mutant\": \"H\", \"log2 fold change IC90\": -0.011587816940911263, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08674440497949672, \"functional effect\": -0.3831, \"times_seen\": 7.0}, {\"site\": 759, \"mutant\": \"K\", \"log2 fold change IC90\": -0.028934620686518576, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08570764539133686, \"functional effect\": -1.9731, \"times_seen\": 7.0}, {\"site\": 759, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015059229315477981, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08653593153321593, \"functional effect\": -1.1412, \"times_seen\": 3.0}, {\"site\": 759, \"mutant\": \"N\", \"log2 fold change IC90\": 0.05016737120590626, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.09053815421374542, \"functional effect\": 0.3165, \"times_seen\": 10.0}, {\"site\": 759, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 759, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": null, \"functional effect\": -0.5475, \"times_seen\": null}, {\"site\": 759, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013267989823095669, \"epitope\": \"all\", \"reference_site\": \"762\", \"IC90\": 0.08664344063321584, \"functional effect\": -0.0864, \"times_seen\": 5.0}, {\"site\": 760, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02449370597391598, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.0889412221889346, \"functional effect\": -1.6237, \"times_seen\": 8.0}, {\"site\": 760, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0019203917021814473, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08756042247050201, \"functional effect\": -0.6558, \"times_seen\": 1.0}, {\"site\": 760, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0011215503687287164, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08737599463416437, \"functional effect\": -0.0134, \"times_seen\": 9.0}, {\"site\": 760, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 760, \"mutant\": \"M\", \"log2 fold change IC90\": -0.005231686465292823, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08712742086023517, \"functional effect\": 0.16, \"times_seen\": 7.0}, {\"site\": 760, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004511802934606266, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08717090700578128, \"functional effect\": -0.4704, \"times_seen\": 1.0}, {\"site\": 760, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02394543043111628, \"epitope\": \"all\", \"reference_site\": \"763\", \"IC90\": 0.08890742777599268, \"functional effect\": -1.5481, \"times_seen\": 1.0}, {\"site\": 761, \"mutant\": \"*\", \"log2 fold change IC90\": -0.01807005901621119, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08635552384996098, \"functional effect\": -2.5877, \"times_seen\": 4.0}, {\"site\": 761, \"mutant\": \"A\", \"log2 fold change IC90\": 0.693088948823191, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.14137425068517012, \"functional effect\": -0.226, \"times_seen\": 37.0}, {\"site\": 761, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04662289652401016, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0846632356914257, \"functional effect\": -0.6222, \"times_seen\": 14.0}, {\"site\": 761, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03383941705869198, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08541675594116735, \"functional effect\": -1.3145, \"times_seen\": 12.0}, {\"site\": 761, \"mutant\": \"E\", \"log2 fold change IC90\": 0.011711860930975246, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08815671005834508, \"functional effect\": -1.8716, \"times_seen\": 17.0}, {\"site\": 761, \"mutant\": \"F\", \"log2 fold change IC90\": -0.022864475533093728, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08606902036223545, \"functional effect\": -1.4497, \"times_seen\": 5.0}, {\"site\": 761, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07920263304885711, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08277275006129067, \"functional effect\": -0.2276, \"times_seen\": 38.0}, {\"site\": 761, \"mutant\": \"H\", \"log2 fold change IC90\": -0.032754664602799556, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08548100436207672, \"functional effect\": -0.085, \"times_seen\": 12.0}, {\"site\": 761, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02152092516046533, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08614921189504103, \"functional effect\": -1.4162, \"times_seen\": 5.0}, {\"site\": 761, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 761, \"mutant\": \"L\", \"log2 fold change IC90\": -0.27890733717823607, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.07207261475682925, \"functional effect\": -0.7349, \"times_seen\": 32.0}, {\"site\": 761, \"mutant\": \"M\", \"log2 fold change IC90\": -0.031957229011910324, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08552826621277677, \"functional effect\": -0.265, \"times_seen\": 20.0}, {\"site\": 761, \"mutant\": \"N\", \"log2 fold change IC90\": -0.010708973833548267, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0867972629604526, \"functional effect\": -0.6305, \"times_seen\": 35.0}, {\"site\": 761, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0026751794832829837, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08760624423217737, \"functional effect\": -2.9308, \"times_seen\": 6.0}, {\"site\": 761, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06596419737502007, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08353578359010441, \"functional effect\": 0.3452, \"times_seen\": 23.0}, {\"site\": 761, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08096237001194395, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08267184899351411, \"functional effect\": 0.1124, \"times_seen\": 69.0}, {\"site\": 761, \"mutant\": \"S\", \"log2 fold change IC90\": -1.6806976695309297, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.027276543829056865, \"functional effect\": -0.3048, \"times_seen\": 47.0}, {\"site\": 761, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08802270041056978, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.0822682538936557, \"functional effect\": -0.0973, \"times_seen\": 35.0}, {\"site\": 761, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005417373434805629, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08711620755099277, \"functional effect\": -0.3854, \"times_seen\": 22.0}, {\"site\": 761, \"mutant\": \"W\", \"log2 fold change IC90\": -0.01939810155705589, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08627606766735074, \"functional effect\": -0.8069, \"times_seen\": 11.0}, {\"site\": 761, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.008694020464901179, \"epitope\": \"all\", \"reference_site\": \"764\", \"IC90\": 0.08797249591877483, \"functional effect\": -0.3796, \"times_seen\": 12.0}, {\"site\": 762, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0020447219782692145, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08732010116192573, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 762, \"mutant\": \"C\", \"log2 fold change IC90\": -0.017604259203472136, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08638340977177894, \"functional effect\": -1.5482, \"times_seen\": 4.0}, {\"site\": 762, \"mutant\": \"G\", \"log2 fold change IC90\": 0.8378150159448162, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.15629216365524312, \"functional effect\": -0.2881, \"times_seen\": 27.0}, {\"site\": 762, \"mutant\": \"H\", \"log2 fold change IC90\": 0.8173945109522618, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.1540955221996036, \"functional effect\": -0.9356, \"times_seen\": 4.0}, {\"site\": 762, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004655284265239083, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08716223796939976, \"functional effect\": -0.0548, \"times_seen\": 9.0}, {\"site\": 762, \"mutant\": \"L\", \"log2 fold change IC90\": 0.016781563904768808, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08846704211564875, \"functional effect\": -0.5001, \"times_seen\": 12.0}, {\"site\": 762, \"mutant\": \"M\", \"log2 fold change IC90\": -0.7371134019343553, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.0524609932205437, \"functional effect\": -0.2185, \"times_seen\": 1.0}, {\"site\": 762, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": null, \"functional effect\": -2.6327, \"times_seen\": null}, {\"site\": 762, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": null, \"functional effect\": -1.1381, \"times_seen\": null}, {\"site\": 762, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 762, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013743306540134842, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08661489940228818, \"functional effect\": -0.495, \"times_seen\": 19.0}, {\"site\": 762, \"mutant\": \"V\", \"log2 fold change IC90\": 0.05332785602604006, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.0907367118496646, \"functional effect\": -0.7384, \"times_seen\": 6.0}, {\"site\": 762, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0032868977349818757, \"epitope\": \"all\", \"reference_site\": \"765\", \"IC90\": 0.08724494998480166, \"functional effect\": -0.9641, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004414023726931245, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08717681524752752, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 763, \"mutant\": \"C\", \"log2 fold change IC90\": 0.011368724002570345, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08813574497233571, \"functional effect\": -0.9905, \"times_seen\": 2.0}, {\"site\": 763, \"mutant\": \"D\", \"log2 fold change IC90\": 0.019385832334242615, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08862688185202161, \"functional effect\": -1.6376, \"times_seen\": 8.0}, {\"site\": 763, \"mutant\": \"F\", \"log2 fold change IC90\": -0.017836609026759622, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08636949861713011, \"functional effect\": -0.6086, \"times_seen\": 3.0}, {\"site\": 763, \"mutant\": \"G\", \"log2 fold change IC90\": -0.005485616379173004, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08711208684236679, \"functional effect\": -1.5951, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01198323706177042, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08817329421258585, \"functional effect\": -0.3293, \"times_seen\": 1.0}, {\"site\": 763, \"mutant\": \"S\", \"log2 fold change IC90\": -0.006735354387413486, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.0870366584648096, \"functional effect\": 0.2056, \"times_seen\": 2.0}, {\"site\": 763, \"mutant\": \"T\", \"log2 fold change IC90\": -0.14596110468753407, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.07902983625573215, \"functional effect\": -0.0657, \"times_seen\": 18.0}, {\"site\": 763, \"mutant\": \"V\", \"log2 fold change IC90\": -0.018811460481234044, \"epitope\": \"all\", \"reference_site\": \"766\", \"IC90\": 0.08631115711832853, \"functional effect\": -0.633, \"times_seen\": 11.0}, {\"site\": 764, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -3.2893, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -2.8309, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"M\", \"log2 fold change IC90\": 0.00938762600668294, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.0880148006881124, \"functional effect\": -0.3954, \"times_seen\": 6.0}, {\"site\": 764, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -2.9957, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.00429126491945596, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.08718423343147715, \"functional effect\": -1.116, \"times_seen\": 1.0}, {\"site\": 764, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": null, \"functional effect\": -3.2678, \"times_seen\": null}, {\"site\": 764, \"mutant\": \"V\", \"log2 fold change IC90\": -0.009046939465351837, \"epitope\": \"all\", \"reference_site\": \"767\", \"IC90\": 0.08689731401642585, \"functional effect\": -2.3797, \"times_seen\": 2.0}, {\"site\": 765, \"mutant\": \"A\", \"log2 fold change IC90\": 0.011934186476235755, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08817029643546367, \"functional effect\": -0.8115, \"times_seen\": 11.0}, {\"site\": 765, \"mutant\": \"E\", \"log2 fold change IC90\": -1.3613079710172313, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.03403574178697397, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 765, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0019937347867020998, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08732318725099823, \"functional effect\": -0.697, \"times_seen\": 11.0}, {\"site\": 765, \"mutant\": \"I\", \"log2 fold change IC90\": -0.7418661083169766, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.05228845401367862, \"functional effect\": -0.4963, \"times_seen\": 43.0}, {\"site\": 765, \"mutant\": \"K\", \"log2 fold change IC90\": -0.04137738182252229, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08497162420944201, \"functional effect\": -1.1789, \"times_seen\": 8.0}, {\"site\": 765, \"mutant\": \"N\", \"log2 fold change IC90\": -0.022510419855712734, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08609014538450707, \"functional effect\": 0.1124, \"times_seen\": 70.0}, {\"site\": 765, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": null, \"functional effect\": -0.6456, \"times_seen\": null}, {\"site\": 765, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03329603122455581, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.08544893391075772, \"functional effect\": -0.4113, \"times_seen\": 7.0}, {\"site\": 765, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"768\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 766, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": null, \"functional effect\": -2.8225, \"times_seen\": null}, {\"site\": 766, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0787685787010868, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09235096922507723, \"functional effect\": -0.3442, \"times_seen\": 112.0}, {\"site\": 766, \"mutant\": \"C\", \"log2 fold change IC90\": -1.2493139133164899, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.03678313922049309, \"functional effect\": -0.7485, \"times_seen\": 108.0}, {\"site\": 766, \"mutant\": \"D\", \"log2 fold change IC90\": 0.2137275691353275, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.1014070530484499, \"functional effect\": -0.2311, \"times_seen\": 125.0}, {\"site\": 766, \"mutant\": \"E\", \"log2 fold change IC90\": -0.027025125663530127, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08582115980107569, \"functional effect\": -0.1186, \"times_seen\": 55.0}, {\"site\": 766, \"mutant\": \"F\", \"log2 fold change IC90\": 0.27444321797001225, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.10576583283871609, \"functional effect\": -0.4384, \"times_seen\": 57.0}, {\"site\": 766, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 766, \"mutant\": \"H\", \"log2 fold change IC90\": 0.09786209152894867, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09358132237557683, \"functional effect\": -0.2743, \"times_seen\": 49.0}, {\"site\": 766, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0035655290294098253, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08722810177685533, \"functional effect\": -0.8515, \"times_seen\": 44.0}, {\"site\": 766, \"mutant\": \"K\", \"log2 fold change IC90\": 0.023931483906287153, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08890656831254368, \"functional effect\": -0.3583, \"times_seen\": 35.0}, {\"site\": 766, \"mutant\": \"L\", \"log2 fold change IC90\": 0.2939558946739174, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.10720604994271896, \"functional effect\": -0.5519, \"times_seen\": 83.0}, {\"site\": 766, \"mutant\": \"M\", \"log2 fold change IC90\": -0.046774147681918656, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08465436012116599, \"functional effect\": -0.1667, \"times_seen\": 23.0}, {\"site\": 766, \"mutant\": \"N\", \"log2 fold change IC90\": 0.05571118584162948, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09088673263012245, \"functional effect\": -0.2105, \"times_seen\": 79.0}, {\"site\": 766, \"mutant\": \"P\", \"log2 fold change IC90\": 0.004694737197991079, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08772896577351741, \"functional effect\": -2.7401, \"times_seen\": 12.0}, {\"site\": 766, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.05407205926918096, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.0842272150415769, \"functional effect\": 0.0564, \"times_seen\": 20.0}, {\"site\": 766, \"mutant\": \"R\", \"log2 fold change IC90\": 0.10444063024760784, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.09400901781463951, \"functional effect\": -0.2939, \"times_seen\": 212.0}, {\"site\": 766, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06751697237066202, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08344592225933326, \"functional effect\": -0.2042, \"times_seen\": 153.0}, {\"site\": 766, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011854605519465315, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08672836536184585, \"functional effect\": -0.6609, \"times_seen\": 65.0}, {\"site\": 766, \"mutant\": \"V\", \"log2 fold change IC90\": 0.013988465371907741, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08829593310142968, \"functional effect\": -0.8462, \"times_seen\": 148.0}, {\"site\": 766, \"mutant\": \"W\", \"log2 fold change IC90\": -0.023526348763302344, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.08602954305523115, \"functional effect\": -0.3517, \"times_seen\": 39.0}, {\"site\": 766, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.30083337921046743, \"epitope\": \"all\", \"reference_site\": \"769\", \"IC90\": 0.10771833295428695, \"functional effect\": -0.1698, \"times_seen\": 58.0}, {\"site\": 767, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 767, \"mutant\": \"L\", \"log2 fold change IC90\": -0.013360591997174666, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08663787943472785, \"functional effect\": -0.5587, \"times_seen\": 3.0}, {\"site\": 767, \"mutant\": \"M\", \"log2 fold change IC90\": -0.014215935673171282, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08658652887427123, \"functional effect\": -0.6704, \"times_seen\": 11.0}, {\"site\": 767, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005394978999443291, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08711755983499285, \"functional effect\": -0.4593, \"times_seen\": 1.0}, {\"site\": 767, \"mutant\": \"T\", \"log2 fold change IC90\": -0.005867882967793977, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08708900807103617, \"functional effect\": -2.8362, \"times_seen\": 1.0}, {\"site\": 767, \"mutant\": \"V\", \"log2 fold change IC90\": -0.07043307637538955, \"epitope\": \"all\", \"reference_site\": \"770\", \"IC90\": 0.08327742426108656, \"functional effect\": -0.2712, \"times_seen\": 18.0}, {\"site\": 768, \"mutant\": \"*\", \"log2 fold change IC90\": 0.02348322415680678, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08887894844545349, \"functional effect\": -2.7602, \"times_seen\": 2.0}, {\"site\": 768, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 768, \"mutant\": \"C\", \"log2 fold change IC90\": 0.041753129336730005, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.09001164468541362, \"functional effect\": -1.0503, \"times_seen\": 18.0}, {\"site\": 768, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004232869263478734, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08718776244030889, \"functional effect\": -2.9103, \"times_seen\": 5.0}, {\"site\": 768, \"mutant\": \"E\", \"log2 fold change IC90\": -0.009795396319942886, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.0868522441848899, \"functional effect\": -2.5854, \"times_seen\": 3.0}, {\"site\": 768, \"mutant\": \"F\", \"log2 fold change IC90\": -0.006987522379820854, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08702144669739333, \"functional effect\": -2.4737, \"times_seen\": 1.0}, {\"site\": 768, \"mutant\": \"G\", \"log2 fold change IC90\": 0.11707741945983688, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.09483607422530732, \"functional effect\": -0.4717, \"times_seen\": 47.0}, {\"site\": 768, \"mutant\": \"H\", \"log2 fold change IC90\": -0.006938106165899969, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.087024427468764, \"functional effect\": -3.0029, \"times_seen\": 1.0}, {\"site\": 768, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011026418861138991, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08677816652800532, \"functional effect\": -2.686, \"times_seen\": 2.0}, {\"site\": 768, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": null, \"functional effect\": -2.9716, \"times_seen\": null}, {\"site\": 768, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015108669530659055, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08653296605427044, \"functional effect\": -2.7146, \"times_seen\": 3.0}, {\"site\": 768, \"mutant\": \"M\", \"log2 fold change IC90\": -0.006708140338848868, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08703830028246573, \"functional effect\": -2.8167, \"times_seen\": 1.0}, {\"site\": 768, \"mutant\": \"N\", \"log2 fold change IC90\": -2.60381148325596, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.014384818723427591, \"functional effect\": -0.1069, \"times_seen\": 19.0}, {\"site\": 768, \"mutant\": \"P\", \"log2 fold change IC90\": 0.015863077662095625, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08841073783878116, \"functional effect\": -2.9758, \"times_seen\": 3.0}, {\"site\": 768, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008043194558666441, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08695779324676613, \"functional effect\": -2.2876, \"times_seen\": 2.0}, {\"site\": 768, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0031375162406739854, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08725398408790898, \"functional effect\": -2.9508, \"times_seen\": 4.0}, {\"site\": 768, \"mutant\": \"S\", \"log2 fold change IC90\": -0.2399593917792538, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.07404483644401177, \"functional effect\": -0.4086, \"times_seen\": 66.0}, {\"site\": 768, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08030766621965568, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08270937449587769, \"functional effect\": -2.2719, \"times_seen\": 15.0}, {\"site\": 768, \"mutant\": \"V\", \"log2 fold change IC90\": 0.07565632748082612, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.09215196000009888, \"functional effect\": -2.6338, \"times_seen\": 10.0}, {\"site\": 768, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": null, \"functional effect\": -2.493, \"times_seen\": null}, {\"site\": 768, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.020465075304704067, \"epitope\": \"all\", \"reference_site\": \"771\", \"IC90\": 0.08869320614237446, \"functional effect\": -2.4901, \"times_seen\": 3.0}, {\"site\": 769, \"mutant\": \"A\", \"log2 fold change IC90\": 0.00027948059137360436, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08746088848214355, \"functional effect\": -1.0373, \"times_seen\": 5.0}, {\"site\": 769, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0172787467197111, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08849753495828364, \"functional effect\": -0.8523, \"times_seen\": 7.0}, {\"site\": 769, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005898196030605668, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.0870871782270547, \"functional effect\": -0.8312, \"times_seen\": 2.0}, {\"site\": 769, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0299638285925013, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08927909186181016, \"functional effect\": -0.7854, \"times_seen\": 5.0}, {\"site\": 769, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0008820467941770214, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.0874974256443544, \"functional effect\": -1.3317, \"times_seen\": 5.0}, {\"site\": 769, \"mutant\": \"I\", \"log2 fold change IC90\": 0.026078766154264625, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08903899383052515, \"functional effect\": -0.3216, \"times_seen\": 19.0}, {\"site\": 769, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03096431533927029, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08558715004646353, \"functional effect\": -0.6707, \"times_seen\": 9.0}, {\"site\": 769, \"mutant\": \"M\", \"log2 fold change IC90\": -0.09838621877785286, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.08167940206102375, \"functional effect\": -0.6794, \"times_seen\": 21.0}, {\"site\": 769, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"772\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": -2.9508, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0027147713165750517, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.08727955538512638, \"functional effect\": -0.6339, \"times_seen\": 5.0}, {\"site\": 770, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"G\", \"log2 fold change IC90\": 0.029376101804385643, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.08924272864860419, \"functional effect\": -1.584, \"times_seen\": 1.0}, {\"site\": 770, \"mutant\": \"K\", \"log2 fold change IC90\": -0.002249410464867644, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": 0.0873077131305149, \"functional effect\": -2.1972, \"times_seen\": 3.0}, {\"site\": 770, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": -1.329, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": 0.5283, \"times_seen\": null}, {\"site\": 770, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"773\", \"IC90\": null, \"functional effect\": -3.2891, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"*\", \"log2 fold change IC90\": -0.009779943363413658, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.08685317447930674, \"functional effect\": -2.8012, \"times_seen\": 3.0}, {\"site\": 771, \"mutant\": \"E\", \"log2 fold change IC90\": -0.003785419800314202, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.0872148077733763, \"functional effect\": -3.2328, \"times_seen\": 1.0}, {\"site\": 771, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": null, \"functional effect\": -1.5265, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"K\", \"log2 fold change IC90\": 0.08481643623185041, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.09273892219596892, \"functional effect\": -2.8752, \"times_seen\": 2.0}, {\"site\": 771, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": null, \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"P\", \"log2 fold change IC90\": -0.002182499792516186, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.08731176246394451, \"functional effect\": -0.3916, \"times_seen\": 1.0}, {\"site\": 771, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 771, \"mutant\": \"R\", \"log2 fold change IC90\": -0.015204540668381209, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": 0.08652721588668105, \"functional effect\": -2.932, \"times_seen\": 2.0}, {\"site\": 771, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"774\", \"IC90\": null, \"functional effect\": -2.9984, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"E\", \"log2 fold change IC90\": -0.00486127141072992, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.08714979388496481, \"functional effect\": -1.7483, \"times_seen\": 2.0}, {\"site\": 772, \"mutant\": \"G\", \"log2 fold change IC90\": -0.004776661467887958, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.08715490512129605, \"functional effect\": -1.6581, \"times_seen\": 1.0}, {\"site\": 772, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.9749, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"N\", \"log2 fold change IC90\": -0.014583638065063544, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.08656446321527862, \"functional effect\": -2.7155, \"times_seen\": 3.0}, {\"site\": 772, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.2599, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.568, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": null, \"functional effect\": -2.4226, \"times_seen\": null}, {\"site\": 772, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0230873536124387, \"epitope\": \"all\", \"reference_site\": \"775\", \"IC90\": 0.08885456371417784, \"functional effect\": -2.5069, \"times_seen\": 1.0}, {\"site\": 773, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0010347899204901489, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.0875066897905969, \"functional effect\": -0.0735, \"times_seen\": 5.0}, {\"site\": 773, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 773, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 773, \"mutant\": \"M\", \"log2 fold change IC90\": 0.006632198255149939, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08784686015332244, \"functional effect\": 0.3651, \"times_seen\": 3.0}, {\"site\": 773, \"mutant\": \"N\", \"log2 fold change IC90\": -0.025819095080487037, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08589293256975139, \"functional effect\": -1.9023, \"times_seen\": 3.0}, {\"site\": 773, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.020637821318831396, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08620196177443737, \"functional effect\": 0.3042, \"times_seen\": 9.0}, {\"site\": 773, \"mutant\": \"R\", \"log2 fold change IC90\": 0.010197651434843337, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08806423195598896, \"functional effect\": 0.1008, \"times_seen\": 22.0}, {\"site\": 773, \"mutant\": \"T\", \"log2 fold change IC90\": -0.010035684304467343, \"epitope\": \"all\", \"reference_site\": \"776\", \"IC90\": 0.08683777971925559, \"functional effect\": 0.2622, \"times_seen\": 2.0}, {\"site\": 774, \"mutant\": \"D\", \"log2 fold change IC90\": 0.02045593968456123, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08869264450956076, \"functional effect\": -1.6319, \"times_seen\": 2.0}, {\"site\": 774, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01740561288904069, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08639530482022609, \"functional effect\": -1.7783, \"times_seen\": 4.0}, {\"site\": 774, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0047650884734660535, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08715560426231185, \"functional effect\": -2.3639, \"times_seen\": 1.0}, {\"site\": 774, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 774, \"mutant\": \"S\", \"log2 fold change IC90\": 0.012561294448333312, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08820863046528045, \"functional effect\": -1.8787, \"times_seen\": 5.0}, {\"site\": 774, \"mutant\": \"T\", \"log2 fold change IC90\": -0.001373483074222389, \"epitope\": \"all\", \"reference_site\": \"777\", \"IC90\": 0.08736073780704794, \"functional effect\": -2.8274, \"times_seen\": 1.0}, {\"site\": 775, \"mutant\": \"A\", \"log2 fold change IC90\": 0.052871152428545724, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.09070799252707924, \"functional effect\": -0.946, \"times_seen\": 13.0}, {\"site\": 775, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03446773041983381, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08955824481182237, \"functional effect\": -2.3628, \"times_seen\": 2.0}, {\"site\": 775, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01909171448255392, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08629439217691094, \"functional effect\": -0.4753, \"times_seen\": 40.0}, {\"site\": 775, \"mutant\": \"N\", \"log2 fold change IC90\": 0.012541184128915054, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08820740089747832, \"functional effect\": -1.1689, \"times_seen\": 12.0}, {\"site\": 775, \"mutant\": \"P\", \"log2 fold change IC90\": 0.021695383318361926, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08876887459642524, \"functional effect\": -2.5316, \"times_seen\": 2.0}, {\"site\": 775, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01896415964189252, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.08860098166254375, \"functional effect\": -0.8224, \"times_seen\": 4.0}, {\"site\": 775, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"778\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 776, \"mutant\": \"*\", \"log2 fold change IC90\": -0.021856352242019657, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.08612918450261907, \"functional effect\": -1.8032, \"times_seen\": 1.0}, {\"site\": 776, \"mutant\": \"E\", \"log2 fold change IC90\": -1.9212916620535214, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.023086778281342132, \"functional effect\": 0.3651, \"times_seen\": 14.0}, {\"site\": 776, \"mutant\": \"H\", \"log2 fold change IC90\": -0.001536359600454002, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.0873508755631775, \"functional effect\": -0.3563, \"times_seen\": 11.0}, {\"site\": 776, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004987174110323955, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.08714218873263072, \"functional effect\": -0.2552, \"times_seen\": 27.0}, {\"site\": 776, \"mutant\": \"L\", \"log2 fold change IC90\": -1.2166819398867668, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.037624608857616856, \"functional effect\": 0.0398, \"times_seen\": 17.0}, {\"site\": 776, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": null, \"functional effect\": -3.2663, \"times_seen\": null}, {\"site\": 776, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 776, \"mutant\": \"R\", \"log2 fold change IC90\": 0.01702383090510415, \"epitope\": \"all\", \"reference_site\": \"779\", \"IC90\": 0.08848189934047566, \"functional effect\": -0.0258, \"times_seen\": 15.0}, {\"site\": 777, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0032148806131701577, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08724930522748091, \"functional effect\": -3.0345, \"times_seen\": 1.0}, {\"site\": 777, \"mutant\": \"A\", \"log2 fold change IC90\": 0.00013144692501153193, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08745191465788203, \"functional effect\": 0.0559, \"times_seen\": 3.0}, {\"site\": 777, \"mutant\": \"D\", \"log2 fold change IC90\": -0.07157072735208503, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08321178093671117, \"functional effect\": 0.2593, \"times_seen\": 26.0}, {\"site\": 777, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 777, \"mutant\": \"G\", \"log2 fold change IC90\": -0.013657837065252643, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08662003087432421, \"functional effect\": -0.1689, \"times_seen\": 14.0}, {\"site\": 777, \"mutant\": \"K\", \"log2 fold change IC90\": 0.005242193439603459, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.0877622624038995, \"functional effect\": -0.0755, \"times_seen\": 21.0}, {\"site\": 777, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": null, \"functional effect\": 0.576, \"times_seen\": null}, {\"site\": 777, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.10977306976028657, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08103726330342294, \"functional effect\": 0.0878, \"times_seen\": 10.0}, {\"site\": 777, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": null, \"functional effect\": -1.6764, \"times_seen\": null}, {\"site\": 777, \"mutant\": \"S\", \"log2 fold change IC90\": -0.018790342160230632, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08631242055932706, \"functional effect\": -0.192, \"times_seen\": 10.0}, {\"site\": 777, \"mutant\": \"V\", \"log2 fold change IC90\": -0.015605457106482373, \"epitope\": \"all\", \"reference_site\": \"780\", \"IC90\": 0.08650317382473663, \"functional effect\": -0.4499, \"times_seen\": 6.0}, {\"site\": 778, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -1.0729, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -2.8674, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -2.9742, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"F\", \"log2 fold change IC90\": -0.011598378534577389, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08674376994868371, \"functional effect\": -1.1213, \"times_seen\": 1.0}, {\"site\": 778, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0263954981223304, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08905854376372813, \"functional effect\": -1.5907, \"times_seen\": 1.0}, {\"site\": 778, \"mutant\": \"L\", \"log2 fold change IC90\": -0.038492351998429535, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08514171625358474, \"functional effect\": -2.2896, \"times_seen\": 9.0}, {\"site\": 778, \"mutant\": \"M\", \"log2 fold change IC90\": -0.008395594112076172, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.08693655511650915, \"functional effect\": -2.2113, \"times_seen\": 2.0}, {\"site\": 778, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": null, \"functional effect\": -1.6866, \"times_seen\": null}, {\"site\": 778, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"781\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0210250514623175, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.0887276387282391, \"functional effect\": -2.2009, \"times_seen\": 3.0}, {\"site\": 779, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": null, \"functional effect\": -2.6266, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005502601335841289, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.08711106127128718, \"functional effect\": -2.3996, \"times_seen\": 2.0}, {\"site\": 779, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": null, \"functional effect\": -2.92, \"times_seen\": null}, {\"site\": 779, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03059430442457942, \"epitope\": \"all\", \"reference_site\": \"782\", \"IC90\": 0.08560910357103044, \"functional effect\": -0.2612, \"times_seen\": 8.0}, {\"site\": 780, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 780, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01879838004747331, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08631193967629094, \"functional effect\": -1.3972, \"times_seen\": 3.0}, {\"site\": 780, \"mutant\": \"D\", \"log2 fold change IC90\": 0.016707322415113784, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08846248969409383, \"functional effect\": -1.0212, \"times_seen\": 2.0}, {\"site\": 780, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005845724806360645, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08709034566981107, \"functional effect\": -0.1269, \"times_seen\": 1.0}, {\"site\": 780, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04566226360282326, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08471962832633356, \"functional effect\": -0.1099, \"times_seen\": 14.0}, {\"site\": 780, \"mutant\": \"H\", \"log2 fold change IC90\": -0.005520793398570636, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08710996282715681, \"functional effect\": -0.5215, \"times_seen\": 1.0}, {\"site\": 780, \"mutant\": \"K\", \"log2 fold change IC90\": -0.026447137895170513, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08585554927141302, \"functional effect\": -0.5208, \"times_seen\": 6.0}, {\"site\": 780, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005876928095272547, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08708846205910137, \"functional effect\": -0.8397, \"times_seen\": 1.0}, {\"site\": 780, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06207774454171377, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08376112266860027, \"functional effect\": -0.7879, \"times_seen\": 22.0}, {\"site\": 780, \"mutant\": \"T\", \"log2 fold change IC90\": -0.12151801774926187, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.08038021888015687, \"functional effect\": -1.0432, \"times_seen\": 39.0}, {\"site\": 780, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05685669758248614, \"epitope\": \"all\", \"reference_site\": \"783\", \"IC90\": 0.0840647994815693, \"functional effect\": -0.59, \"times_seen\": 47.0}, {\"site\": 781, \"mutant\": \"*\", \"log2 fold change IC90\": -0.019925785574839067, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08624451687123495, \"functional effect\": -2.5266, \"times_seen\": 1.0}, {\"site\": 781, \"mutant\": \"H\", \"log2 fold change IC90\": -2.6033696762690384, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.01438922456558668, \"functional effect\": 0.1042, \"times_seen\": 16.0}, {\"site\": 781, \"mutant\": \"K\", \"log2 fold change IC90\": -0.06685966044713348, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08348395004429485, \"functional effect\": -0.2481, \"times_seen\": 11.0}, {\"site\": 781, \"mutant\": \"L\", \"log2 fold change IC90\": 0.31929815597656575, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.10910585961385154, \"functional effect\": 0.0136, \"times_seen\": 49.0}, {\"site\": 781, \"mutant\": \"P\", \"log2 fold change IC90\": -0.03350282557990137, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08543668663025993, \"functional effect\": -1.9129, \"times_seen\": 5.0}, {\"site\": 781, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 781, \"mutant\": \"R\", \"log2 fold change IC90\": -0.09712723325674626, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08175071170306612, \"functional effect\": 0.0575, \"times_seen\": 60.0}, {\"site\": 781, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0314847829054978, \"epitope\": \"all\", \"reference_site\": \"784\", \"IC90\": 0.08555627914146467, \"functional effect\": -0.377, \"times_seen\": 5.0}, {\"site\": 782, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02628768174522479, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08905188843430262, \"functional effect\": -0.4484, \"times_seen\": 14.0}, {\"site\": 782, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": null, \"functional effect\": -0.5647, \"times_seen\": null}, {\"site\": 782, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0044566111581330475, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08717424188190295, \"functional effect\": -1.1697, \"times_seen\": 1.0}, {\"site\": 782, \"mutant\": \"I\", \"log2 fold change IC90\": -0.049780514666658775, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08447813640264522, \"functional effect\": -0.1905, \"times_seen\": 16.0}, {\"site\": 782, \"mutant\": \"L\", \"log2 fold change IC90\": -0.028054398286896647, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08575995361050003, \"functional effect\": -1.029, \"times_seen\": 8.0}, {\"site\": 782, \"mutant\": \"M\", \"log2 fold change IC90\": 0.012373050969075058, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08819712171548807, \"functional effect\": -1.0268, \"times_seen\": 8.0}, {\"site\": 782, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.031003221885985487, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.08934343638530012, \"functional effect\": -0.767, \"times_seen\": 4.0}, {\"site\": 782, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": null, \"functional effect\": -0.3291, \"times_seen\": null}, {\"site\": 782, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"785\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 783, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01189253575458877, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08672608519593898, \"functional effect\": 0.0321, \"times_seen\": 3.0}, {\"site\": 783, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 783, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": null, \"functional effect\": -0.2916, \"times_seen\": null}, {\"site\": 783, \"mutant\": \"N\", \"log2 fold change IC90\": -0.030197115389447762, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08563267589740711, \"functional effect\": -0.2182, \"times_seen\": 9.0}, {\"site\": 783, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010100819879144365, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08683385920879283, \"functional effect\": -0.0847, \"times_seen\": 2.0}, {\"site\": 783, \"mutant\": \"R\", \"log2 fold change IC90\": 0.02271759259943655, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08883179331393745, \"functional effect\": 0.0834, \"times_seen\": 8.0}, {\"site\": 783, \"mutant\": \"T\", \"log2 fold change IC90\": 0.010416298777777491, \"epitope\": \"all\", \"reference_site\": \"786\", \"IC90\": 0.08807757952352553, \"functional effect\": -0.3067, \"times_seen\": 7.0}, {\"site\": 784, \"mutant\": \"*\", \"log2 fold change IC90\": -0.02879462545614395, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08571596263330349, \"functional effect\": -2.609, \"times_seen\": 4.0}, {\"site\": 784, \"mutant\": \"H\", \"log2 fold change IC90\": -0.15979917671628857, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.07827542013950578, \"functional effect\": -0.1617, \"times_seen\": 51.0}, {\"site\": 784, \"mutant\": \"K\", \"log2 fold change IC90\": 0.012823477348779063, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08822466219442844, \"functional effect\": -0.249, \"times_seen\": 36.0}, {\"site\": 784, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009817233681298158, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08685092955537155, \"functional effect\": -0.255, \"times_seen\": 16.0}, {\"site\": 784, \"mutant\": \"N\", \"log2 fold change IC90\": 0.019103083354526578, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08860951386763215, \"functional effect\": -0.6562, \"times_seen\": 8.0}, {\"site\": 784, \"mutant\": \"P\", \"log2 fold change IC90\": -1.3239063510045326, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.03492964965846543, \"functional effect\": -0.731, \"times_seen\": 1.0}, {\"site\": 784, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 784, \"mutant\": \"R\", \"log2 fold change IC90\": -0.026779223693654507, \"epitope\": \"all\", \"reference_site\": \"787\", \"IC90\": 0.08583578894325077, \"functional effect\": -1.191, \"times_seen\": 9.0}, {\"site\": 785, \"mutant\": \"F\", \"log2 fold change IC90\": 1.824843756738291, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.309786480758579, \"functional effect\": -2.6049, \"times_seen\": 2.0}, {\"site\": 785, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 785, \"mutant\": \"L\", \"log2 fold change IC90\": 0.06959532873624803, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.09176562657889162, \"functional effect\": 0.3002, \"times_seen\": 18.0}, {\"site\": 785, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05243046932730944, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.08432310865678562, \"functional effect\": -0.317, \"times_seen\": 13.0}, {\"site\": 785, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004385936303495686, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.08717851248491287, \"functional effect\": -0.9981, \"times_seen\": 2.0}, {\"site\": 785, \"mutant\": \"T\", \"log2 fold change IC90\": 0.00430260848372496, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.0877051240253662, \"functional effect\": -3.162, \"times_seen\": 1.0}, {\"site\": 785, \"mutant\": \"V\", \"log2 fold change IC90\": 0.041120467720860955, \"epitope\": \"all\", \"reference_site\": \"788\", \"IC90\": 0.08997218074716735, \"functional effect\": -1.9642, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"*\", \"log2 fold change IC90\": -0.008989203222850092, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08690079169164194, \"functional effect\": -2.8941, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"C\", \"log2 fold change IC90\": -0.007565131626881476, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08698661304919274, \"functional effect\": -2.9036, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"H\", \"log2 fold change IC90\": -0.043560504736436745, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08484314021868357, \"functional effect\": 0.0132, \"times_seen\": 13.0}, {\"site\": 786, \"mutant\": \"N\", \"log2 fold change IC90\": 0.03144703942177474, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.0893709254127071, \"functional effect\": -2.782, \"times_seen\": 3.0}, {\"site\": 786, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02748226301682598, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08912565577221376, \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 786, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006307949683873778, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.08706244727464879, \"functional effect\": -2.8037, \"times_seen\": 3.0}, {\"site\": 786, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"789\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": null, \"functional effect\": -3.2755, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"E\", \"log2 fold change IC90\": 0.03769731658869995, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08975895254358938, \"functional effect\": -2.1323, \"times_seen\": 13.0}, {\"site\": 787, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": null, \"functional effect\": -2.6097, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0025354248793764828, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08759775818167916, \"functional effect\": -0.6658, \"times_seen\": 2.0}, {\"site\": 787, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 787, \"mutant\": \"M\", \"log2 fold change IC90\": 0.001822103283709703, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08755445732745662, \"functional effect\": -0.5911, \"times_seen\": 3.0}, {\"site\": 787, \"mutant\": \"N\", \"log2 fold change IC90\": -0.026482330555322398, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08585345496303201, \"functional effect\": -1.1482, \"times_seen\": 18.0}, {\"site\": 787, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.045876616695852176, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.09026928250811049, \"functional effect\": -0.3125, \"times_seen\": 14.0}, {\"site\": 787, \"mutant\": \"R\", \"log2 fold change IC90\": 0.012733945342648736, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08821918724256522, \"functional effect\": 0.187, \"times_seen\": 16.0}, {\"site\": 787, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05638914229684001, \"epitope\": \"all\", \"reference_site\": \"790\", \"IC90\": 0.08409204800601276, \"functional effect\": 0.0374, \"times_seen\": 8.0}, {\"site\": 788, \"mutant\": \"A\", \"log2 fold change IC90\": -0.026692989372367148, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.0858409197657851, \"functional effect\": 0.064, \"times_seen\": 7.0}, {\"site\": 788, \"mutant\": \"H\", \"log2 fold change IC90\": -0.015017394500887626, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08653844091117725, \"functional effect\": -0.09, \"times_seen\": 6.0}, {\"site\": 788, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011521450513831636, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.0867483954615324, \"functional effect\": -0.0181, \"times_seen\": 25.0}, {\"site\": 788, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03122874837438351, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08557146412864215, \"functional effect\": -0.5386, \"times_seen\": 23.0}, {\"site\": 788, \"mutant\": \"N\", \"log2 fold change IC90\": -0.015018580047285564, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08653836979753796, \"functional effect\": -0.9177, \"times_seen\": 3.0}, {\"site\": 788, \"mutant\": \"P\", \"log2 fold change IC90\": -0.012206427784170738, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.08670721796143428, \"functional effect\": 0.036, \"times_seen\": 5.0}, {\"site\": 788, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": null, \"functional effect\": -0.6799, \"times_seen\": null}, {\"site\": 788, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": null, \"functional effect\": -0.0459, \"times_seen\": null}, {\"site\": 788, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"791\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": null, \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": null, \"functional effect\": 0.6623, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0033903114194604677, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.0872386964120659, \"functional effect\": -0.6043, \"times_seen\": 7.0}, {\"site\": 789, \"mutant\": \"L\", \"log2 fold change IC90\": 0.024726395425839976, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08895556850103166, \"functional effect\": -0.4385, \"times_seen\": 36.0}, {\"site\": 789, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": null, \"functional effect\": -0.9385, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 789, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.029243521596513052, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08568929616661691, \"functional effect\": -0.2454, \"times_seen\": 4.0}, {\"site\": 789, \"mutant\": \"R\", \"log2 fold change IC90\": 0.2824753130867581, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.10635631829999949, \"functional effect\": -0.6375, \"times_seen\": 4.0}, {\"site\": 789, \"mutant\": \"S\", \"log2 fold change IC90\": -0.015164730772548724, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08652960356174738, \"functional effect\": -0.269, \"times_seen\": 11.0}, {\"site\": 789, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04132970455296807, \"epitope\": \"all\", \"reference_site\": \"792\", \"IC90\": 0.08497443234411968, \"functional effect\": -0.2892, \"times_seen\": 20.0}, {\"site\": 790, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": null, \"functional effect\": -2.5815, \"times_seen\": null}, {\"site\": 790, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08005194522191944, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08272403622116879, \"functional effect\": -0.053, \"times_seen\": 26.0}, {\"site\": 790, \"mutant\": \"N\", \"log2 fold change IC90\": -0.018301149919345745, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08634169252924334, \"functional effect\": 0.3933, \"times_seen\": 16.0}, {\"site\": 790, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 790, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0013209832657017368, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08736391693037496, \"functional effect\": 0.2878, \"times_seen\": 9.0}, {\"site\": 790, \"mutant\": \"R\", \"log2 fold change IC90\": 0.007962467723219393, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08792789868598076, \"functional effect\": 0.3498, \"times_seen\": 1.0}, {\"site\": 790, \"mutant\": \"S\", \"log2 fold change IC90\": -0.4370070036433032, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.0645918221722668, \"functional effect\": 0.3254, \"times_seen\": 26.0}, {\"site\": 790, \"mutant\": \"T\", \"log2 fold change IC90\": -0.025251423058723507, \"epitope\": \"all\", \"reference_site\": \"793\", \"IC90\": 0.08592673639344116, \"functional effect\": 0.1526, \"times_seen\": 8.0}, {\"site\": 791, \"mutant\": \"F\", \"log2 fold change IC90\": 0.014348595554383187, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08831797656778395, \"functional effect\": 0.31, \"times_seen\": 12.0}, {\"site\": 791, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 791, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 791, \"mutant\": \"L\", \"log2 fold change IC90\": -0.008065633763380509, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08695644074433542, \"functional effect\": -0.5619, \"times_seen\": 2.0}, {\"site\": 791, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 791, \"mutant\": \"N\", \"log2 fold change IC90\": 0.021349776759890693, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08874761200801429, \"functional effect\": 0.2922, \"times_seen\": 3.0}, {\"site\": 791, \"mutant\": \"T\", \"log2 fold change IC90\": 0.015806312173304665, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.0884072592241937, \"functional effect\": 0.3158, \"times_seen\": 9.0}, {\"site\": 791, \"mutant\": \"V\", \"log2 fold change IC90\": 0.005831994698664258, \"epitope\": \"all\", \"reference_site\": \"794\", \"IC90\": 0.08779814862624379, \"functional effect\": 0.0945, \"times_seen\": 4.0}, {\"site\": 792, \"mutant\": \"E\", \"log2 fold change IC90\": -0.009372739994779788, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08687769240990131, \"functional effect\": -0.9126, \"times_seen\": 14.0}, {\"site\": 792, \"mutant\": \"I\", \"log2 fold change IC90\": 0.003095593936192668, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08763177720841404, \"functional effect\": -0.2489, \"times_seen\": 2.0}, {\"site\": 792, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 792, \"mutant\": \"M\", \"log2 fold change IC90\": -0.002410280534463694, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.0872979782839588, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 792, \"mutant\": \"N\", \"log2 fold change IC90\": 0.025979241977260082, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08903285169606, \"functional effect\": 0.1416, \"times_seen\": 34.0}, {\"site\": 792, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0034304801675677844, \"epitope\": \"all\", \"reference_site\": \"795\", \"IC90\": 0.08765212113495767, \"functional effect\": 0.4099, \"times_seen\": 23.0}, {\"site\": 793, \"mutant\": \"*\", \"log2 fold change IC90\": -0.010181767125661812, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08682898724041409, \"functional effect\": -3.0468, \"times_seen\": 2.0}, {\"site\": 793, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0710820153734545, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08323997364662057, \"functional effect\": -0.2063, \"times_seen\": 20.0}, {\"site\": 793, \"mutant\": \"C\", \"log2 fold change IC90\": 0.049896899640896705, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.09052118201917238, \"functional effect\": -0.1096, \"times_seen\": 18.0}, {\"site\": 793, \"mutant\": \"D\", \"log2 fold change IC90\": -6.487919018234971, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.0009742524775670531, \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 793, \"mutant\": \"E\", \"log2 fold change IC90\": -0.03135851636190803, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08556376746581523, \"functional effect\": 0.3958, \"times_seen\": 14.0}, {\"site\": 793, \"mutant\": \"F\", \"log2 fold change IC90\": -0.023409918593650436, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08603648619858394, \"functional effect\": -1.3189, \"times_seen\": 15.0}, {\"site\": 793, \"mutant\": \"G\", \"log2 fold change IC90\": -0.1765857484325347, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.07736991963276123, \"functional effect\": 0.1069, \"times_seen\": 27.0}, {\"site\": 793, \"mutant\": \"H\", \"log2 fold change IC90\": -0.12285368665470725, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08030583609455234, \"functional effect\": 0.3463, \"times_seen\": 26.0}, {\"site\": 793, \"mutant\": \"I\", \"log2 fold change IC90\": -0.04634673804575343, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08467944334969016, \"functional effect\": 0.1034, \"times_seen\": 16.0}, {\"site\": 793, \"mutant\": \"K\", \"log2 fold change IC90\": -0.017855210463565595, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08636838501628749, \"functional effect\": -0.3197, \"times_seen\": 3.0}, {\"site\": 793, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0757959555223103, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08296843469698269, \"functional effect\": 0.3055, \"times_seen\": 21.0}, {\"site\": 793, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0021512160414663595, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08757443284207442, \"functional effect\": 0.0388, \"times_seen\": 3.0}, {\"site\": 793, \"mutant\": \"N\", \"log2 fold change IC90\": -0.12403982755423594, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08023983816208773, \"functional effect\": 0.4141, \"times_seen\": 44.0}, {\"site\": 793, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": null, \"functional effect\": -2.8316, \"times_seen\": null}, {\"site\": 793, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013820076778229344, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08661029047985788, \"functional effect\": -0.2016, \"times_seen\": 4.0}, {\"site\": 793, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0008777750524689397, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08739075999329161, \"functional effect\": -1.0075, \"times_seen\": 13.0}, {\"site\": 793, \"mutant\": \"S\", \"log2 fold change IC90\": -1.7712168720403902, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.02561771238963312, \"functional effect\": 0.4444, \"times_seen\": 52.0}, {\"site\": 793, \"mutant\": \"T\", \"log2 fold change IC90\": -0.09008940070233806, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08215048673168403, \"functional effect\": 0.0623, \"times_seen\": 20.0}, {\"site\": 793, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0029270023574062133, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08762153726438447, \"functional effect\": -0.0814, \"times_seen\": 26.0}, {\"site\": 793, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0024379217009261444, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.08729630572339309, \"functional effect\": -1.3168, \"times_seen\": 7.0}, {\"site\": 793, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"796\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 794, \"mutant\": \"C\", \"log2 fold change IC90\": -0.015148407951009985, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08653058257340739, \"functional effect\": -1.1026, \"times_seen\": 6.0}, {\"site\": 794, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 794, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005326192871442696, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08712171360437015, \"functional effect\": -0.7217, \"times_seen\": 2.0}, {\"site\": 794, \"mutant\": \"L\", \"log2 fold change IC90\": -0.028176226986860953, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08575271189812779, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 794, \"mutant\": \"S\", \"log2 fold change IC90\": 0.14874097303924055, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.09694049819082383, \"functional effect\": -1.0526, \"times_seen\": 4.0}, {\"site\": 794, \"mutant\": \"V\", \"log2 fold change IC90\": 0.05817820864438472, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.09104228280097025, \"functional effect\": -1.2891, \"times_seen\": 2.0}, {\"site\": 794, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00667269009050722, \"epitope\": \"all\", \"reference_site\": \"797\", \"IC90\": 0.08704043903471918, \"functional effect\": -0.3219, \"times_seen\": 2.0}, {\"site\": 795, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0008059567233098694, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08739511047236692, \"functional effect\": 0.0924, \"times_seen\": 3.0}, {\"site\": 795, \"mutant\": \"C\", \"log2 fold change IC90\": -0.015747379059409743, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08649466468372703, \"functional effect\": -1.6839, \"times_seen\": 2.0}, {\"site\": 795, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01454060415030383, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08656704537102568, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 795, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004717430998729105, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08715848337709071, \"functional effect\": -2.0077, \"times_seen\": 1.0}, {\"site\": 795, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 795, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01691126630142688, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08642491367103121, \"functional effect\": -0.3295, \"times_seen\": 4.0}, {\"site\": 795, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0678316375040259, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.09165351186412633, \"functional effect\": -0.3617, \"times_seen\": 10.0}, {\"site\": 795, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": null, \"functional effect\": -2.8864, \"times_seen\": null}, {\"site\": 795, \"mutant\": \"W\", \"log2 fold change IC90\": -0.02685031331593185, \"epitope\": \"all\", \"reference_site\": \"798\", \"IC90\": 0.08583155943992346, \"functional effect\": -0.7709, \"times_seen\": 3.0}, {\"site\": 796, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02975658651377663, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08565882794301408, \"functional effect\": -2.0614, \"times_seen\": 6.0}, {\"site\": 796, \"mutant\": \"D\", \"log2 fold change IC90\": -0.008474050223659926, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08693182749326343, \"functional effect\": -2.0504, \"times_seen\": 9.0}, {\"site\": 796, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 796, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 796, \"mutant\": \"S\", \"log2 fold change IC90\": -0.006450879717466542, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08705382229032006, \"functional effect\": -2.6231, \"times_seen\": 2.0}, {\"site\": 796, \"mutant\": \"V\", \"log2 fold change IC90\": -0.008410843088202028, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08693563622068588, \"functional effect\": -3.0068, \"times_seen\": 2.0}, {\"site\": 796, \"mutant\": \"W\", \"log2 fold change IC90\": -0.003223821684508521, \"epitope\": \"all\", \"reference_site\": \"799\", \"IC90\": 0.08724876450347284, \"functional effect\": -1.0263, \"times_seen\": 1.0}, {\"site\": 797, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 797, \"mutant\": \"I\", \"log2 fold change IC90\": 0.047686206973482075, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.09038257942841271, \"functional effect\": -2.5187, \"times_seen\": 2.0}, {\"site\": 797, \"mutant\": \"L\", \"log2 fold change IC90\": 0.011104970297394582, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.08811963345615571, \"functional effect\": -2.5735, \"times_seen\": 4.0}, {\"site\": 797, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0030279542383952565, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.08726061063332344, \"functional effect\": -2.3392, \"times_seen\": 1.0}, {\"site\": 797, \"mutant\": \"V\", \"log2 fold change IC90\": -0.003958250411285987, \"epitope\": \"all\", \"reference_site\": \"800\", \"IC90\": 0.08720436032242625, \"functional effect\": -2.9684, \"times_seen\": 1.0}, {\"site\": 798, \"mutant\": \"D\", \"log2 fold change IC90\": 0.029562004871934243, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.08925422904577651, \"functional effect\": 0.1322, \"times_seen\": 18.0}, {\"site\": 798, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": null, \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 798, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012383983380380579, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.0866965473733933, \"functional effect\": -2.2033, \"times_seen\": 1.0}, {\"site\": 798, \"mutant\": \"K\", \"log2 fold change IC90\": -0.00926534161306341, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.08688416007674135, \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 798, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 798, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"801\", \"IC90\": null, \"functional effect\": -3.0358, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -2.0436, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -3.1372, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014347080686867292, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": 0.08657865827439358, \"functional effect\": -2.1336, \"times_seen\": 3.0}, {\"site\": 799, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -1.5288, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 799, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"802\", \"IC90\": null, \"functional effect\": -0.9458, \"times_seen\": null}, {\"site\": 800, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0017829981102247578, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08755208413995408, \"functional effect\": -0.9067, \"times_seen\": 2.0}, {\"site\": 800, \"mutant\": \"F\", \"log2 fold change IC90\": 0.014714230213027214, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08834036259163472, \"functional effect\": -2.2039, \"times_seen\": 4.0}, {\"site\": 800, \"mutant\": \"G\", \"log2 fold change IC90\": 0.01578097667292234, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08840570669755479, \"functional effect\": -0.764, \"times_seen\": 3.0}, {\"site\": 800, \"mutant\": \"H\", \"log2 fold change IC90\": 0.015765925264496765, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.0884047843796568, \"functional effect\": -0.5422, \"times_seen\": 7.0}, {\"site\": 800, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": null, \"functional effect\": -2.8923, \"times_seen\": null}, {\"site\": 800, \"mutant\": \"L\", \"log2 fold change IC90\": 0.003270149095411028, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08764238063035146, \"functional effect\": -1.4122, \"times_seen\": 15.0}, {\"site\": 800, \"mutant\": \"N\", \"log2 fold change IC90\": -0.033720354773588423, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.08542380547937295, \"functional effect\": -0.3901, \"times_seen\": 8.0}, {\"site\": 800, \"mutant\": \"R\", \"log2 fold change IC90\": -0.013851265621167475, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.0866084181191222, \"functional effect\": -0.2646, \"times_seen\": 3.0}, {\"site\": 800, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 800, \"mutant\": \"T\", \"log2 fold change IC90\": -0.010881641099063474, \"epitope\": \"all\", \"reference_site\": \"803\", \"IC90\": 0.0867868753533651, \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 801, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": null, \"functional effect\": -1.5857, \"times_seen\": null}, {\"site\": 801, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": null, \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 801, \"mutant\": \"H\", \"log2 fold change IC90\": 0.029472699326793424, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08924870421159227, \"functional effect\": -0.4395, \"times_seen\": 11.0}, {\"site\": 801, \"mutant\": \"K\", \"log2 fold change IC90\": -0.005385138862791438, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08711815403653425, \"functional effect\": -0.1603, \"times_seen\": 17.0}, {\"site\": 801, \"mutant\": \"L\", \"log2 fold change IC90\": -0.00919539062927598, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08688837287268511, \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 801, \"mutant\": \"P\", \"log2 fold change IC90\": 0.008739291756279077, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08797525650980102, \"functional effect\": 0.3861, \"times_seen\": 5.0}, {\"site\": 801, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 801, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0059176160031233745, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.0870860059632171, \"functional effect\": -0.0333, \"times_seen\": 7.0}, {\"site\": 801, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0022331692335957375, \"epitope\": \"all\", \"reference_site\": \"804\", \"IC90\": 0.08757940770368264, \"functional effect\": 0.1817, \"times_seen\": 3.0}, {\"site\": 802, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 802, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009007645135410716, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.08689968084942418, \"functional effect\": 0.0932, \"times_seen\": 4.0}, {\"site\": 802, \"mutant\": \"M\", \"log2 fold change IC90\": -0.000559155593850871, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.08741006238970554, \"functional effect\": -0.5141, \"times_seen\": 19.0}, {\"site\": 802, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": null, \"functional effect\": -3.1385, \"times_seen\": null}, {\"site\": 802, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": null, \"functional effect\": -3.15, \"times_seen\": null}, {\"site\": 802, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0009618287445436649, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": 0.08750226444125511, \"functional effect\": -0.3151, \"times_seen\": 4.0}, {\"site\": 802, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"805\", \"IC90\": null, \"functional effect\": -2.9677, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009713790419471865, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08685715711233041, \"functional effect\": -0.2975, \"times_seen\": 2.0}, {\"site\": 803, \"mutant\": \"I\", \"log2 fold change IC90\": -0.009719287732568492, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08685682614836084, \"functional effect\": -1.7201, \"times_seen\": 2.0}, {\"site\": 803, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"M\", \"log2 fold change IC90\": -0.003977973027478944, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08720316818803595, \"functional effect\": 0.0086, \"times_seen\": 3.0}, {\"site\": 803, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": null, \"functional effect\": -2.1869, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": null, \"functional effect\": -2.8206, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": null, \"functional effect\": -2.3767, \"times_seen\": null}, {\"site\": 803, \"mutant\": \"V\", \"log2 fold change IC90\": 0.008254499536439057, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08794569894313214, \"functional effect\": -1.5347, \"times_seen\": 5.0}, {\"site\": 803, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.014127284913905533, \"epitope\": \"all\", \"reference_site\": \"806\", \"IC90\": 0.08830442955450772, \"functional effect\": -0.0491, \"times_seen\": 3.0}, {\"site\": 804, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 804, \"mutant\": \"H\", \"log2 fold change IC90\": -0.07015018651390846, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08329375525842644, \"functional effect\": -0.766, \"times_seen\": 11.0}, {\"site\": 804, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05465671292436884, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08419308879101625, \"functional effect\": -1.3191, \"times_seen\": 21.0}, {\"site\": 804, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 804, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.002314404297220864, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08758433925114126, \"functional effect\": -0.3064, \"times_seen\": 9.0}, {\"site\": 804, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": null, \"functional effect\": -1.7397, \"times_seen\": null}, {\"site\": 804, \"mutant\": \"S\", \"log2 fold change IC90\": -1.2687428519216346, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.03629109712079719, \"functional effect\": -0.0774, \"times_seen\": 61.0}, {\"site\": 804, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013461991868651074, \"epitope\": \"all\", \"reference_site\": \"807\", \"IC90\": 0.08663179030232741, \"functional effect\": -0.4701, \"times_seen\": 3.0}, {\"site\": 805, \"mutant\": \"A\", \"log2 fold change IC90\": 0.013185007671242798, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08824677351141308, \"functional effect\": -1.2046, \"times_seen\": 5.0}, {\"site\": 805, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 805, \"mutant\": \"E\", \"log2 fold change IC90\": -0.009057133967296993, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.0868966999769499, \"functional effect\": -0.2332, \"times_seen\": 11.0}, {\"site\": 805, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0902659022243467, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.082140436930021, \"functional effect\": -1.829, \"times_seen\": 17.0}, {\"site\": 805, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0027037759363690134, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08728022058153, \"functional effect\": -0.8279, \"times_seen\": 30.0}, {\"site\": 805, \"mutant\": \"I\", \"log2 fold change IC90\": 0.047267751642042916, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.09035636766039029, \"functional effect\": -1.4157, \"times_seen\": 4.0}, {\"site\": 805, \"mutant\": \"N\", \"log2 fold change IC90\": -0.06792952181160934, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08342206368496614, \"functional effect\": -0.4902, \"times_seen\": 37.0}, {\"site\": 805, \"mutant\": \"R\", \"log2 fold change IC90\": 0.011110036905886692, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08811994292451494, \"functional effect\": -1.0512, \"times_seen\": 3.0}, {\"site\": 805, \"mutant\": \"S\", \"log2 fold change IC90\": -0.012085745911092963, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.0867144713496047, \"functional effect\": -0.6862, \"times_seen\": 3.0}, {\"site\": 805, \"mutant\": \"V\", \"log2 fold change IC90\": -0.014605400728768635, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08656315742365975, \"functional effect\": -0.0955, \"times_seen\": 5.0}, {\"site\": 805, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.011643802604165067, \"epitope\": \"all\", \"reference_site\": \"808\", \"IC90\": 0.08674103881500622, \"functional effect\": -2.7158, \"times_seen\": 3.0}, {\"site\": 806, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": null, \"functional effect\": -1.2617, \"times_seen\": null}, {\"site\": 806, \"mutant\": \"H\", \"log2 fold change IC90\": 0.029419580784441384, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08924541822691341, \"functional effect\": -0.4214, \"times_seen\": 3.0}, {\"site\": 806, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00682423950030779, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08785855447734812, \"functional effect\": -0.1099, \"times_seen\": 24.0}, {\"site\": 806, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 806, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.04471849870329106, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.0847750673256283, \"functional effect\": -0.1306, \"times_seen\": 14.0}, {\"site\": 806, \"mutant\": \"R\", \"log2 fold change IC90\": 0.021808937315917088, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08877586183696641, \"functional effect\": -0.3906, \"times_seen\": 2.0}, {\"site\": 806, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004528729614351968, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08716988426339403, \"functional effect\": -0.0518, \"times_seen\": 11.0}, {\"site\": 806, \"mutant\": \"T\", \"log2 fold change IC90\": -0.11074523389420841, \"epitope\": \"all\", \"reference_site\": \"809\", \"IC90\": 0.08098267450880696, \"functional effect\": -0.1149, \"times_seen\": 28.0}, {\"site\": 807, \"mutant\": \"A\", \"log2 fold change IC90\": 0.04273604625159586, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.09007299106240955, \"functional effect\": -0.0312, \"times_seen\": 19.0}, {\"site\": 807, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03709794990516435, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08522404770710099, \"functional effect\": -0.0043, \"times_seen\": 8.0}, {\"site\": 807, \"mutant\": \"I\", \"log2 fold change IC90\": 0.09188237959669947, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.09319424732775929, \"functional effect\": -0.3514, \"times_seen\": 25.0}, {\"site\": 807, \"mutant\": \"L\", \"log2 fold change IC90\": -0.042112985393995085, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08492830979024969, \"functional effect\": -0.1477, \"times_seen\": 15.0}, {\"site\": 807, \"mutant\": \"N\", \"log2 fold change IC90\": -0.045415457370776284, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08473412281080085, \"functional effect\": -0.4062, \"times_seen\": 25.0}, {\"site\": 807, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.9404910370290295, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.0455631498647328, \"functional effect\": 0.1263, \"times_seen\": 17.0}, {\"site\": 807, \"mutant\": \"R\", \"log2 fold change IC90\": 1.2818810829855742, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.2126250406631375, \"functional effect\": -0.1915, \"times_seen\": 12.0}, {\"site\": 807, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 807, \"mutant\": \"T\", \"log2 fold change IC90\": 0.018854516945570946, \"epitope\": \"all\", \"reference_site\": \"810\", \"IC90\": 0.08859424837441403, \"functional effect\": 0.0096, \"times_seen\": 15.0}, {\"site\": 808, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": null, \"functional effect\": -3.1474, \"times_seen\": null}, {\"site\": 808, \"mutant\": \"E\", \"log2 fold change IC90\": -0.020588888340086858, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08620488560114992, \"functional effect\": -1.267, \"times_seen\": 5.0}, {\"site\": 808, \"mutant\": \"I\", \"log2 fold change IC90\": 0.004253491338458073, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08770213811922158, \"functional effect\": -0.1502, \"times_seen\": 4.0}, {\"site\": 808, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 808, \"mutant\": \"N\", \"log2 fold change IC90\": 0.09184747730967639, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.09319199276048622, \"functional effect\": -0.5554, \"times_seen\": 14.0}, {\"site\": 808, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.021791639747293527, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08877479744198828, \"functional effect\": -0.1551, \"times_seen\": 11.0}, {\"site\": 808, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03475831360229915, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08536236872224008, \"functional effect\": -0.1412, \"times_seen\": 19.0}, {\"site\": 808, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03586423409076872, \"epitope\": \"all\", \"reference_site\": \"811\", \"IC90\": 0.08529695793503023, \"functional effect\": -0.082, \"times_seen\": 6.0}, {\"site\": 809, \"mutant\": \"A\", \"log2 fold change IC90\": 0.026287597779484174, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08905188325142796, \"functional effect\": -0.1726, \"times_seen\": 8.0}, {\"site\": 809, \"mutant\": \"L\", \"log2 fold change IC90\": -1.0043299111731852, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.043590949005729504, \"functional effect\": -0.2061, \"times_seen\": 26.0}, {\"site\": 809, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 809, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.003350257600802734, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08764724728258952, \"functional effect\": -0.082, \"times_seen\": 10.0}, {\"site\": 809, \"mutant\": \"R\", \"log2 fold change IC90\": -0.024465193541491823, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08597357688749824, \"functional effect\": -0.2985, \"times_seen\": 10.0}, {\"site\": 809, \"mutant\": \"S\", \"log2 fold change IC90\": -0.011205079624960089, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.08676742074103688, \"functional effect\": -0.2188, \"times_seen\": 18.0}, {\"site\": 809, \"mutant\": \"T\", \"log2 fold change IC90\": 0.11617131377071328, \"epitope\": \"all\", \"reference_site\": \"812\", \"IC90\": 0.09477652974477967, \"functional effect\": 0.0767, \"times_seen\": 35.0}, {\"site\": 810, \"mutant\": \"*\", \"log2 fold change IC90\": -0.004165946366829845, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08719180694922002, \"functional effect\": -2.1747, \"times_seen\": 1.0}, {\"site\": 810, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05052400266105603, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.09056053783880583, \"functional effect\": -0.7802, \"times_seen\": 23.0}, {\"site\": 810, \"mutant\": \"C\", \"log2 fold change IC90\": -0.010004927049209574, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08683963106008101, \"functional effect\": -1.1521, \"times_seen\": 26.0}, {\"site\": 810, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0038422176586497647, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08767714015409214, \"functional effect\": 0.0399, \"times_seen\": 11.0}, {\"site\": 810, \"mutant\": \"E\", \"log2 fold change IC90\": 0.8344955501680625, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.15593296779199078, \"functional effect\": -0.3491, \"times_seen\": 9.0}, {\"site\": 810, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02326964168451417, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08886579141647945, \"functional effect\": -0.5532, \"times_seen\": 7.0}, {\"site\": 810, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07276153133227649, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08314312606907605, \"functional effect\": 0.2633, \"times_seen\": 110.0}, {\"site\": 810, \"mutant\": \"H\", \"log2 fold change IC90\": -0.017985093277516222, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08636060980141297, \"functional effect\": -0.7006, \"times_seen\": 8.0}, {\"site\": 810, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03533412059393873, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08532830577764873, \"functional effect\": -0.4102, \"times_seen\": 41.0}, {\"site\": 810, \"mutant\": \"K\", \"log2 fold change IC90\": -0.08600313834805669, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08238349806101214, \"functional effect\": -0.7068, \"times_seen\": 20.0}, {\"site\": 810, \"mutant\": \"L\", \"log2 fold change IC90\": -0.6666581890567609, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.05508655851666541, \"functional effect\": -1.0156, \"times_seen\": 30.0}, {\"site\": 810, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00799249753545602, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08696084904067751, \"functional effect\": -0.6356, \"times_seen\": 15.0}, {\"site\": 810, \"mutant\": \"N\", \"log2 fold change IC90\": 0.2902346424461012, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.10692988160916338, \"functional effect\": -0.5575, \"times_seen\": 54.0}, {\"site\": 810, \"mutant\": \"P\", \"log2 fold change IC90\": -0.027728989756611273, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08577929946475568, \"functional effect\": -2.0002, \"times_seen\": 6.0}, {\"site\": 810, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0021830019078725575, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08757636232807742, \"functional effect\": -0.3979, \"times_seen\": 7.0}, {\"site\": 810, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08017795081007331, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08271681138476776, \"functional effect\": -0.7631, \"times_seen\": 62.0}, {\"site\": 810, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 810, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08214543211933582, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.0826040828767117, \"functional effect\": -0.017, \"times_seen\": 27.0}, {\"site\": 810, \"mutant\": \"V\", \"log2 fold change IC90\": -0.08718985951963501, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08231575953021852, \"functional effect\": -0.6807, \"times_seen\": 12.0}, {\"site\": 810, \"mutant\": \"W\", \"log2 fold change IC90\": 0.018597396324303135, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.08857846029879374, \"functional effect\": -0.7585, \"times_seen\": 13.0}, {\"site\": 810, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.058753068264816306, \"epitope\": \"all\", \"reference_site\": \"813\", \"IC90\": 0.0910785669491123, \"functional effect\": -1.1562, \"times_seen\": 18.0}, {\"site\": 811, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0015843352088634655, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08734797083168334, \"functional effect\": 0.1731, \"times_seen\": 13.0}, {\"site\": 811, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 811, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 811, \"mutant\": \"M\", \"log2 fold change IC90\": 0.02659506745533292, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08907086416619175, \"functional effect\": -0.1107, \"times_seen\": 5.0}, {\"site\": 811, \"mutant\": \"N\", \"log2 fold change IC90\": -0.016917423693990283, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08642454481207623, \"functional effect\": -0.7483, \"times_seen\": 11.0}, {\"site\": 811, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.001646162182292669, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08734422759780411, \"functional effect\": 0.3921, \"times_seen\": 19.0}, {\"site\": 811, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0006280120745663654, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08740589061017034, \"functional effect\": -0.3986, \"times_seen\": 48.0}, {\"site\": 811, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02683610199493042, \"epitope\": \"all\", \"reference_site\": \"814\", \"IC90\": 0.08583240493104698, \"functional effect\": -0.3278, \"times_seen\": 7.0}, {\"site\": 812, \"mutant\": \"G\", \"log2 fold change IC90\": -0.010420281519315478, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.08681463337434586, \"functional effect\": -2.9512, \"times_seen\": 2.0}, {\"site\": 812, \"mutant\": \"K\", \"log2 fold change IC90\": 0.012923933162180858, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.08823080555010374, \"functional effect\": 0.2028, \"times_seen\": 19.0}, {\"site\": 812, \"mutant\": \"M\", \"log2 fold change IC90\": -0.034145685777299296, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.08539862480253459, \"functional effect\": -0.5388, \"times_seen\": 8.0}, {\"site\": 812, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 812, \"mutant\": \"S\", \"log2 fold change IC90\": -0.011281673127121455, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": 0.08676281433148557, \"functional effect\": -2.9839, \"times_seen\": 2.0}, {\"site\": 812, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"815\", \"IC90\": null, \"functional effect\": -3.0625, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.4196, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.9671, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.4335, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0047900594839535736, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": 0.08715409573513763, \"functional effect\": -3.0622, \"times_seen\": 1.0}, {\"site\": 813, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 813, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004993044641208498, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": 0.08714183413941802, \"functional effect\": -2.7514, \"times_seen\": 1.0}, {\"site\": 813, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"816\", \"IC90\": null, \"functional effect\": -2.9258, \"times_seen\": null}, {\"site\": 814, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": null, \"functional effect\": -2.0337, \"times_seen\": null}, {\"site\": 814, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005401754720220258, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08711715068208296, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 814, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 814, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0122818885480935, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08819154880583727, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01657306105386371, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.0864451762939862, \"functional effect\": 0.0834, \"times_seen\": 25.0}, {\"site\": 814, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02348603972428393, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08603194676256694, \"functional effect\": 0.2055, \"times_seen\": 6.0}, {\"site\": 814, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02099767104234393, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08618046320201336, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 814, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.014900606035690697, \"epitope\": \"all\", \"reference_site\": \"817\", \"IC90\": 0.08654544661958793, \"functional effect\": -0.2441, \"times_seen\": 3.0}, {\"site\": 815, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -1.803, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -1.02, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -0.2899, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": null, \"functional effect\": -2.8965, \"times_seen\": null}, {\"site\": 815, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0001270213954812737, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": 0.08745164639575717, \"functional effect\": -2.8434, \"times_seen\": 1.0}, {\"site\": 815, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0040520174328574675, \"epitope\": \"all\", \"reference_site\": \"818\", \"IC90\": 0.08719869271618683, \"functional effect\": -1.0312, \"times_seen\": 1.0}, {\"site\": 816, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -3.1856, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -2.2359, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01269126869761569, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.08667808349962339, \"functional effect\": -1.8798, \"times_seen\": 2.0}, {\"site\": 816, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"G\", \"log2 fold change IC90\": -0.21267721682694174, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.075458389378256, \"functional effect\": -2.0993, \"times_seen\": 3.0}, {\"site\": 816, \"mutant\": \"K\", \"log2 fold change IC90\": 0.028930186879241926, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": 0.08921514935137893, \"functional effect\": -2.1785, \"times_seen\": 1.0}, {\"site\": 816, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -2.6892, \"times_seen\": null}, {\"site\": 816, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"819\", \"IC90\": null, \"functional effect\": -2.9667, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"A\", \"log2 fold change IC90\": 0.03002672479743704, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08928298418714878, \"functional effect\": -2.2577, \"times_seen\": 2.0}, {\"site\": 817, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"E\", \"log2 fold change IC90\": 0.017955115821231674, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08853903439501934, \"functional effect\": -0.1336, \"times_seen\": 4.0}, {\"site\": 817, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0017905765926870452, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08733548483965235, \"functional effect\": -1.7228, \"times_seen\": 2.0}, {\"site\": 817, \"mutant\": \"H\", \"log2 fold change IC90\": -0.006588197010655234, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08704553680654094, \"functional effect\": -0.7693, \"times_seen\": 1.0}, {\"site\": 817, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": null, \"functional effect\": -2.0701, \"times_seen\": null}, {\"site\": 817, \"mutant\": \"N\", \"log2 fold change IC90\": -0.30619299778908043, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.07072231626084088, \"functional effect\": -0.8352, \"times_seen\": 37.0}, {\"site\": 817, \"mutant\": \"V\", \"log2 fold change IC90\": -0.015549872307819094, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": 0.08650650672184455, \"functional effect\": -2.0232, \"times_seen\": 2.0}, {\"site\": 817, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"820\", \"IC90\": null, \"functional effect\": -2.7805, \"times_seen\": null}, {\"site\": 818, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 818, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0021082006224290685, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08757182176027249, \"functional effect\": 0.1336, \"times_seen\": 11.0}, {\"site\": 818, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 818, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03214002449796228, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08551743011080491, \"functional effect\": -0.5161, \"times_seen\": 9.0}, {\"site\": 818, \"mutant\": \"P\", \"log2 fold change IC90\": -0.015157491749423727, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.0865300377431613, \"functional effect\": -1.8992, \"times_seen\": 4.0}, {\"site\": 818, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.007811559365230346, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08697175607452005, \"functional effect\": -1.7887, \"times_seen\": 2.0}, {\"site\": 818, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0018844574575426346, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.0873298018201294, \"functional effect\": -2.6414, \"times_seen\": 1.0}, {\"site\": 818, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011105812463968068, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.08677339113090297, \"functional effect\": -0.3849, \"times_seen\": 17.0}, {\"site\": 818, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008645927617591786, \"epitope\": \"all\", \"reference_site\": \"821\", \"IC90\": 0.0869214713711957, \"functional effect\": -2.4362, \"times_seen\": 2.0}, {\"site\": 819, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.669, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"F\", \"log2 fold change IC90\": 0.7986736659011817, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.1521088500311627, \"functional effect\": -0.815, \"times_seen\": 4.0}, {\"site\": 819, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.0771, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"M\", \"log2 fold change IC90\": -0.021523200725873357, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.0861490760118458, \"functional effect\": -0.6487, \"times_seen\": 6.0}, {\"site\": 819, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.2833, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": null, \"functional effect\": -1.8673, \"times_seen\": null}, {\"site\": 819, \"mutant\": \"R\", \"log2 fold change IC90\": 0.008031411405975599, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.08793210069529696, \"functional effect\": -2.6705, \"times_seen\": 1.0}, {\"site\": 819, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0052665503872789685, \"epitope\": \"all\", \"reference_site\": \"822\", \"IC90\": 0.08776374410226086, \"functional effect\": -1.7285, \"times_seen\": 1.0}, {\"site\": 820, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": null, \"functional effect\": -3.146, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": null, \"functional effect\": -3.0631, \"times_seen\": null}, {\"site\": 820, \"mutant\": \"L\", \"log2 fold change IC90\": -0.026530245857775206, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.08585060361480346, \"functional effect\": -2.1796, \"times_seen\": 4.0}, {\"site\": 820, \"mutant\": \"S\", \"log2 fold change IC90\": -0.025033498400113385, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.08593971693923785, \"functional effect\": -2.2322, \"times_seen\": 3.0}, {\"site\": 820, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01600294113765406, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.08647934419123837, \"functional effect\": -2.1635, \"times_seen\": 1.0}, {\"site\": 820, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.9571866649100059, \"epitope\": \"all\", \"reference_site\": \"823\", \"IC90\": 0.045038908315311106, \"functional effect\": 0.0194, \"times_seen\": 28.0}, {\"site\": 821, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 821, \"mutant\": \"D\", \"log2 fold change IC90\": -0.009927771539968917, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08684427537847997, \"functional effect\": 0.273, \"times_seen\": 14.0}, {\"site\": 821, \"mutant\": \"H\", \"log2 fold change IC90\": -0.013537137162735548, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08662727805154942, \"functional effect\": -1.0801, \"times_seen\": 3.0}, {\"site\": 821, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": null, \"functional effect\": -2.998, \"times_seen\": null}, {\"site\": 821, \"mutant\": \"K\", \"log2 fold change IC90\": -0.012102670255658844, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08671345410275609, \"functional effect\": -0.5735, \"times_seen\": 7.0}, {\"site\": 821, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 821, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0037865463499827997, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08721473967043586, \"functional effect\": 0.1575, \"times_seen\": 1.0}, {\"site\": 821, \"mutant\": \"S\", \"log2 fold change IC90\": 0.003021600618803349, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08762728284235424, \"functional effect\": 0.2537, \"times_seen\": 7.0}, {\"site\": 821, \"mutant\": \"T\", \"log2 fold change IC90\": -0.015833574280413588, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.08648949713007548, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 821, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.12619105435360348, \"epitope\": \"all\", \"reference_site\": \"824\", \"IC90\": 0.09543705851030594, \"functional effect\": -1.385, \"times_seen\": 12.0}, {\"site\": 822, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -3.0041, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"E\", \"log2 fold change IC90\": 0.022172391807060324, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08879822973140032, \"functional effect\": -1.0352, \"times_seen\": 13.0}, {\"site\": 822, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -0.7183, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 822, \"mutant\": \"M\", \"log2 fold change IC90\": -0.005517430879153526, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08711016585640033, \"functional effect\": -1.034, \"times_seen\": 1.0}, {\"site\": 822, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005818333768726845, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08709199918459683, \"functional effect\": -2.8967, \"times_seen\": 1.0}, {\"site\": 822, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01376367749153963, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08661367640269382, \"functional effect\": -0.0144, \"times_seen\": 4.0}, {\"site\": 822, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03634886732828481, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": 0.08526830960856575, \"functional effect\": -0.3462, \"times_seen\": 15.0}, {\"site\": 822, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"825\", \"IC90\": null, \"functional effect\": -0.9509, \"times_seen\": null}, {\"site\": 823, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": null, \"functional effect\": -1.7544, \"times_seen\": null}, {\"site\": 823, \"mutant\": \"A\", \"log2 fold change IC90\": 0.027469330165740338, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08912485682050535, \"functional effect\": -1.3643, \"times_seen\": 4.0}, {\"site\": 823, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": null, \"functional effect\": -1.6687, \"times_seen\": null}, {\"site\": 823, \"mutant\": \"G\", \"log2 fold change IC90\": 0.04860752431511237, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.09044031694736558, \"functional effect\": -2.364, \"times_seen\": 4.0}, {\"site\": 823, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01798445792507325, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08854083515532318, \"functional effect\": -0.3888, \"times_seen\": 6.0}, {\"site\": 823, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06897531568433, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08336161385480115, \"functional effect\": -0.625, \"times_seen\": 45.0}, {\"site\": 823, \"mutant\": \"M\", \"log2 fold change IC90\": 0.008825266156354896, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08798049936782655, \"functional effect\": -0.2696, \"times_seen\": 16.0}, {\"site\": 823, \"mutant\": \"S\", \"log2 fold change IC90\": -0.011638588436625087, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.08674135231378002, \"functional effect\": -2.0156, \"times_seen\": 3.0}, {\"site\": 823, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"826\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"A\", \"log2 fold change IC90\": -0.07737968680284404, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08287740533499549, \"functional effect\": -0.6488, \"times_seen\": 46.0}, {\"site\": 824, \"mutant\": \"H\", \"log2 fold change IC90\": -0.048621100162759764, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08454605411286538, \"functional effect\": -0.916, \"times_seen\": 8.0}, {\"site\": 824, \"mutant\": \"I\", \"log2 fold change IC90\": -0.039910075794018715, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08505808933031817, \"functional effect\": -0.2732, \"times_seen\": 48.0}, {\"site\": 824, \"mutant\": \"L\", \"log2 fold change IC90\": -0.016532383628392575, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08644761368836935, \"functional effect\": -1.6449, \"times_seen\": 4.0}, {\"site\": 824, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00610526345415823, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08707467965801918, \"functional effect\": -0.3136, \"times_seen\": 3.0}, {\"site\": 824, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": null, \"functional effect\": -1.2831, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00214042145660329, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08731430907784721, \"functional effect\": -0.2808, \"times_seen\": 17.0}, {\"site\": 824, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 824, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009393666560092906, \"epitope\": \"all\", \"reference_site\": \"827\", \"IC90\": 0.08687643224162776, \"functional effect\": -2.4549, \"times_seen\": 2.0}, {\"site\": 825, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 825, \"mutant\": \"F\", \"log2 fold change IC90\": -0.06533136388535395, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.0835724343277877, \"functional effect\": 0.2707, \"times_seen\": 22.0}, {\"site\": 825, \"mutant\": \"I\", \"log2 fold change IC90\": -1.0287858651181998, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.04285824155982802, \"functional effect\": 0.0602, \"times_seen\": 15.0}, {\"site\": 825, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 825, \"mutant\": \"M\", \"log2 fold change IC90\": -0.025679910177208002, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.08590121954369584, \"functional effect\": 0.1565, \"times_seen\": 8.0}, {\"site\": 825, \"mutant\": \"P\", \"log2 fold change IC90\": -0.017881806913552945, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": 0.0863667928078208, \"functional effect\": -2.2066, \"times_seen\": 1.0}, {\"site\": 825, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"828\", \"IC90\": null, \"functional effect\": -1.3233, \"times_seen\": null}, {\"site\": 826, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 826, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 826, \"mutant\": \"D\", \"log2 fold change IC90\": 0.024326268856146117, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08893090039719764, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 826, \"mutant\": \"L\", \"log2 fold change IC90\": -0.21927574276649253, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.07511404965829571, \"functional effect\": -0.4038, \"times_seen\": 20.0}, {\"site\": 826, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005109213902122461, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08713481755267, \"functional effect\": -1.0234, \"times_seen\": 1.0}, {\"site\": 826, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.022196290981155786, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08879970074354739, \"functional effect\": 0.0163, \"times_seen\": 4.0}, {\"site\": 826, \"mutant\": \"S\", \"log2 fold change IC90\": 0.011601115542667483, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08814994315743786, \"functional effect\": 0.0185, \"times_seen\": 53.0}, {\"site\": 826, \"mutant\": \"T\", \"log2 fold change IC90\": -0.026983804872599697, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.08582361787356194, \"functional effect\": 0.059, \"times_seen\": 60.0}, {\"site\": 826, \"mutant\": \"V\", \"log2 fold change IC90\": 0.14932050270751032, \"epitope\": \"all\", \"reference_site\": \"829\", \"IC90\": 0.09697944694880153, \"functional effect\": -0.3378, \"times_seen\": 95.0}, {\"site\": 827, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": null, \"functional effect\": -1.3044, \"times_seen\": null}, {\"site\": 827, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 827, \"mutant\": \"E\", \"log2 fold change IC90\": -4.186639677472066, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.00480203840278311, \"functional effect\": -0.7465, \"times_seen\": 18.0}, {\"site\": 827, \"mutant\": \"G\", \"log2 fold change IC90\": -0.3128731963503014, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.0703956034030003, \"functional effect\": -0.7345, \"times_seen\": 41.0}, {\"site\": 827, \"mutant\": \"H\", \"log2 fold change IC90\": -0.014714601201951396, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08655660553310515, \"functional effect\": -0.7527, \"times_seen\": 3.0}, {\"site\": 827, \"mutant\": \"N\", \"log2 fold change IC90\": -0.11194590658921101, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08091530529113006, \"functional effect\": -0.3931, \"times_seen\": 32.0}, {\"site\": 827, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.01279033194127743, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08822263528735122, \"functional effect\": -1.811, \"times_seen\": 5.0}, {\"site\": 827, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01970629456364746, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08625763907360445, \"functional effect\": -2.2549, \"times_seen\": 2.0}, {\"site\": 827, \"mutant\": \"T\", \"log2 fold change IC90\": -0.015933610748160482, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.08648350015664491, \"functional effect\": -1.3214, \"times_seen\": 5.0}, {\"site\": 827, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.01376504305121239, \"epitope\": \"all\", \"reference_site\": \"830\", \"IC90\": 0.0882822602500835, \"functional effect\": -1.3884, \"times_seen\": 22.0}, {\"site\": 828, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": null, \"functional effect\": -1.3054, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010114925344936467, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08683301022407446, \"functional effect\": 0.3178, \"times_seen\": 8.0}, {\"site\": 828, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"K\", \"log2 fold change IC90\": 0.012394732802956578, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08819844721370998, \"functional effect\": -0.0031, \"times_seen\": 11.0}, {\"site\": 828, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": null, \"functional effect\": -0.1246, \"times_seen\": null}, {\"site\": 828, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05778198206458086, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08401090110809666, \"functional effect\": 0.3553, \"times_seen\": 16.0}, {\"site\": 828, \"mutant\": \"T\", \"log2 fold change IC90\": -0.41897039861468827, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.06540441951991291, \"functional effect\": 0.0957, \"times_seen\": 74.0}, {\"site\": 828, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005597465601218267, \"epitope\": \"all\", \"reference_site\": \"831\", \"IC90\": 0.08710533348064868, \"functional effect\": -0.7777, \"times_seen\": 42.0}, {\"site\": 829, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0026519505668901096, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08728335597105967, \"functional effect\": -0.0156, \"times_seen\": 1.0}, {\"site\": 829, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": null, \"functional effect\": -2.6684, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"D\", \"log2 fold change IC90\": -0.10016477027485536, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08157876990345006, \"functional effect\": -0.1105, \"times_seen\": 49.0}, {\"site\": 829, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"N\", \"log2 fold change IC90\": 0.027325030200272087, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08911594289881915, \"functional effect\": -0.7725, \"times_seen\": 1.0}, {\"site\": 829, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": null, \"functional effect\": -1.0359, \"times_seen\": null}, {\"site\": 829, \"mutant\": \"S\", \"log2 fold change IC90\": 0.40519191570579705, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.11579896386018046, \"functional effect\": -0.731, \"times_seen\": 29.0}, {\"site\": 829, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0295622496945647, \"epitope\": \"all\", \"reference_site\": \"832\", \"IC90\": 0.08567036730852422, \"functional effect\": -1.0164, \"times_seen\": 6.0}, {\"site\": 830, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 830, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 830, \"mutant\": \"H\", \"log2 fold change IC90\": 0.00955887934787999, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08802524899693832, \"functional effect\": -1.5015, \"times_seen\": 3.0}, {\"site\": 830, \"mutant\": \"I\", \"log2 fold change IC90\": -0.028981516473063854, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.0857048594511313, \"functional effect\": -0.0113, \"times_seen\": 5.0}, {\"site\": 830, \"mutant\": \"L\", \"log2 fold change IC90\": 0.030227025803817618, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08929538092560656, \"functional effect\": 0.1191, \"times_seen\": 16.0}, {\"site\": 830, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0479432597864759, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08458578683022705, \"functional effect\": -0.1784, \"times_seen\": 12.0}, {\"site\": 830, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0051222643328252245, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08713402934606859, \"functional effect\": -0.0873, \"times_seen\": 1.0}, {\"site\": 830, \"mutant\": \"W\", \"log2 fold change IC90\": -0.018842258413315605, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08630931461058665, \"functional effect\": -0.4468, \"times_seen\": 8.0}, {\"site\": 830, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.027820906613098082, \"epitope\": \"all\", \"reference_site\": \"833\", \"IC90\": 0.08577383447584949, \"functional effect\": 0.098, \"times_seen\": 5.0}, {\"site\": 831, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 831, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04632007466849573, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08468100837954362, \"functional effect\": 0.1099, \"times_seen\": 16.0}, {\"site\": 831, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 831, \"mutant\": \"L\", \"log2 fold change IC90\": 0.11331344010930698, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.09458897018357092, \"functional effect\": 0.0544, \"times_seen\": 8.0}, {\"site\": 831, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": null, \"functional effect\": -0.9074, \"times_seen\": null}, {\"site\": 831, \"mutant\": \"N\", \"log2 fold change IC90\": 0.02916120191490088, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08922943628696059, \"functional effect\": 0.1654, \"times_seen\": 17.0}, {\"site\": 831, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03718753317243117, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08521875593621565, \"functional effect\": -0.1605, \"times_seen\": 6.0}, {\"site\": 831, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06479049500564232, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08360377165259346, \"functional effect\": -0.0861, \"times_seen\": 23.0}, {\"site\": 831, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0028218176548621384, \"epitope\": \"all\", \"reference_site\": \"834\", \"IC90\": 0.08727307958120617, \"functional effect\": 0.3875, \"times_seen\": 15.0}, {\"site\": 832, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": null, \"functional effect\": -2.0011, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": null, \"functional effect\": -1.3295, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"E\", \"log2 fold change IC90\": -0.04165849238094662, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08495506901720833, \"functional effect\": 0.2586, \"times_seen\": 26.0}, {\"site\": 832, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0017112646942650622, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08754773099964538, \"functional effect\": -0.5358, \"times_seen\": 4.0}, {\"site\": 832, \"mutant\": \"I\", \"log2 fold change IC90\": -0.019920098920374576, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08624485682092604, \"functional effect\": -0.2355, \"times_seen\": 5.0}, {\"site\": 832, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": null, \"functional effect\": -1.8672, \"times_seen\": null}, {\"site\": 832, \"mutant\": \"N\", \"log2 fold change IC90\": -0.021681446487210758, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08613962704439775, \"functional effect\": -0.5423, \"times_seen\": 10.0}, {\"site\": 832, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.07349679186999633, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.09201412312907226, \"functional effect\": -0.4526, \"times_seen\": 13.0}, {\"site\": 832, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0157928193188646, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.08840643239616129, \"functional effect\": -0.0165, \"times_seen\": 61.0}, {\"site\": 832, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0025561144882971227, \"epitope\": \"all\", \"reference_site\": \"835\", \"IC90\": 0.0875990144252395, \"functional effect\": -0.0234, \"times_seen\": 10.0}, {\"site\": 833, \"mutant\": \"*\", \"log2 fold change IC90\": 0.03301601044096135, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08946817165144201, \"functional effect\": -2.9421, \"times_seen\": 1.0}, {\"site\": 833, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": null, \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 833, \"mutant\": \"E\", \"log2 fold change IC90\": 0.016560134139058734, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08845346493362552, \"functional effect\": -0.1667, \"times_seen\": 16.0}, {\"site\": 833, \"mutant\": \"H\", \"log2 fold change IC90\": 1.062177022435349, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.1825899615981958, \"functional effect\": -0.4189, \"times_seen\": 47.0}, {\"site\": 833, \"mutant\": \"K\", \"log2 fold change IC90\": -0.031842717224405535, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08553505516198005, \"functional effect\": -0.2839, \"times_seen\": 15.0}, {\"site\": 833, \"mutant\": \"L\", \"log2 fold change IC90\": 0.10674228176089048, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.09415911792944215, \"functional effect\": 0.1973, \"times_seen\": 37.0}, {\"site\": 833, \"mutant\": \"M\", \"log2 fold change IC90\": -0.045893361915202775, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08470605858736377, \"functional effect\": 0.3236, \"times_seen\": 7.0}, {\"site\": 833, \"mutant\": \"P\", \"log2 fold change IC90\": 0.009631549760310306, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08802968305408736, \"functional effect\": -0.4693, \"times_seen\": 8.0}, {\"site\": 833, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 833, \"mutant\": \"R\", \"log2 fold change IC90\": -0.07071860302204773, \"epitope\": \"all\", \"reference_site\": \"836\", \"IC90\": 0.08326094429116578, \"functional effect\": -0.1702, \"times_seen\": 23.0}, {\"site\": 834, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": null, \"functional effect\": -2.8644, \"times_seen\": null}, {\"site\": 834, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": null, \"functional effect\": -1.3526, \"times_seen\": null}, {\"site\": 834, \"mutant\": \"C\", \"log2 fold change IC90\": 0.019970783435790618, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08866282354590206, \"functional effect\": -2.569, \"times_seen\": 3.0}, {\"site\": 834, \"mutant\": \"F\", \"log2 fold change IC90\": -0.16217409254494825, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.07814667178741122, \"functional effect\": -0.1285, \"times_seen\": 21.0}, {\"site\": 834, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0256325261298588, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08590404093989051, \"functional effect\": -0.2107, \"times_seen\": 12.0}, {\"site\": 834, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01658331965554476, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08644456160865575, \"functional effect\": -1.874, \"times_seen\": 4.0}, {\"site\": 834, \"mutant\": \"N\", \"log2 fold change IC90\": 0.022842459240244504, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08883948212366138, \"functional effect\": -0.9393, \"times_seen\": 2.0}, {\"site\": 834, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005632138854276516, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08710324004517435, \"functional effect\": -2.1686, \"times_seen\": 1.0}, {\"site\": 834, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004185064539462137, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.08719065151655737, \"functional effect\": 0.0472, \"times_seen\": 9.0}, {\"site\": 834, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"837\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": null, \"functional effect\": -2.4752, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"A\", \"log2 fold change IC90\": -0.018509477203579348, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08632922556209156, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 835, \"mutant\": \"C\", \"log2 fold change IC90\": 2.5889480243083156, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.5261150984468156, \"functional effect\": -1.8205, \"times_seen\": 3.0}, {\"site\": 835, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04722485988002168, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.0846279173925868, \"functional effect\": -0.0613, \"times_seen\": 24.0}, {\"site\": 835, \"mutant\": \"E\", \"log2 fold change IC90\": -0.12077843329592254, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08042143562997989, \"functional effect\": -0.3981, \"times_seen\": 21.0}, {\"site\": 835, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 835, \"mutant\": \"L\", \"log2 fold change IC90\": 0.002173103824971709, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08757576148375737, \"functional effect\": -1.2886, \"times_seen\": 2.0}, {\"site\": 835, \"mutant\": \"R\", \"log2 fold change IC90\": -0.20135779419415858, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.07605276655464091, \"functional effect\": -0.3667, \"times_seen\": 36.0}, {\"site\": 835, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03641292455370554, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08526452368713654, \"functional effect\": 0.3395, \"times_seen\": 21.0}, {\"site\": 835, \"mutant\": \"V\", \"log2 fold change IC90\": 0.017237406756494843, \"epitope\": \"all\", \"reference_site\": \"838\", \"IC90\": 0.08849499912616364, \"functional effect\": -0.8123, \"times_seen\": 5.0}, {\"site\": 836, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 836, \"mutant\": \"A\", \"log2 fold change IC90\": 0.004389103554518097, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08771038243972798, \"functional effect\": -0.9998, \"times_seen\": 2.0}, {\"site\": 836, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 836, \"mutant\": \"E\", \"log2 fold change IC90\": 0.12495075370928477, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.09535504549014549, \"functional effect\": -0.4425, \"times_seen\": 31.0}, {\"site\": 836, \"mutant\": \"G\", \"log2 fold change IC90\": 1.9523155384977244, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.338403846552353, \"functional effect\": -1.9107, \"times_seen\": 21.0}, {\"site\": 836, \"mutant\": \"H\", \"log2 fold change IC90\": 0.008069292828259605, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08793440959404294, \"functional effect\": -0.3722, \"times_seen\": 1.0}, {\"site\": 836, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": null, \"functional effect\": -0.6005, \"times_seen\": null}, {\"site\": 836, \"mutant\": \"N\", \"log2 fold change IC90\": 0.04710960433085483, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.09034646339579622, \"functional effect\": -1.0207, \"times_seen\": 28.0}, {\"site\": 836, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02393292576372787, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08600530182310864, \"functional effect\": -1.0149, \"times_seen\": 7.0}, {\"site\": 836, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006971426085242179, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08702241760989737, \"functional effect\": -0.6912, \"times_seen\": 4.0}, {\"site\": 836, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04208508174184358, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.0849299524332649, \"functional effect\": -1.0975, \"times_seen\": 11.0}, {\"site\": 836, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.03576664675171798, \"epitope\": \"all\", \"reference_site\": \"839\", \"IC90\": 0.08963891400867233, \"functional effect\": -0.5629, \"times_seen\": 24.0}, {\"site\": 837, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 837, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0045783094103041926, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08716688862627703, \"functional effect\": -2.8542, \"times_seen\": 1.0}, {\"site\": 837, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 837, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": null, \"functional effect\": -1.6807, \"times_seen\": null}, {\"site\": 837, \"mutant\": \"G\", \"log2 fold change IC90\": -0.012746357768787938, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08667477377455313, \"functional effect\": -2.2287, \"times_seen\": 3.0}, {\"site\": 837, \"mutant\": \"R\", \"log2 fold change IC90\": -0.006000774125300907, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08708098639927056, \"functional effect\": -1.4463, \"times_seen\": 1.0}, {\"site\": 837, \"mutant\": \"S\", \"log2 fold change IC90\": -0.017463316740274362, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08639184931370762, \"functional effect\": -2.8114, \"times_seen\": 4.0}, {\"site\": 837, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.014182649721812036, \"epitope\": \"all\", \"reference_site\": \"840\", \"IC90\": 0.08830781838683294, \"functional effect\": -2.6818, \"times_seen\": 4.0}, {\"site\": 838, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": null, \"functional effect\": -1.2992, \"times_seen\": null}, {\"site\": 838, \"mutant\": \"F\", \"log2 fold change IC90\": -0.02101415924647262, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08617947827248285, \"functional effect\": 0.0767, \"times_seen\": 28.0}, {\"site\": 838, \"mutant\": \"I\", \"log2 fold change IC90\": -0.055908602623152365, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08412006244760624, \"functional effect\": -0.1726, \"times_seen\": 30.0}, {\"site\": 838, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 838, \"mutant\": \"M\", \"log2 fold change IC90\": -0.015122012828689002, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08653216572586891, \"functional effect\": -0.2628, \"times_seen\": 6.0}, {\"site\": 838, \"mutant\": \"N\", \"log2 fold change IC90\": 0.023384600313190257, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.088872872813626, \"functional effect\": -1.1094, \"times_seen\": 10.0}, {\"site\": 838, \"mutant\": \"P\", \"log2 fold change IC90\": -0.02092757860743725, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08618465032755115, \"functional effect\": -2.31, \"times_seen\": 2.0}, {\"site\": 838, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.011527302044126955, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08674804361320666, \"functional effect\": -0.888, \"times_seen\": 1.0}, {\"site\": 838, \"mutant\": \"R\", \"log2 fold change IC90\": -3.724483261983338, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.006615285204077264, \"functional effect\": -0.6282, \"times_seen\": 16.0}, {\"site\": 838, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011310148131198879, \"epitope\": \"all\", \"reference_site\": \"841\", \"IC90\": 0.08676110187872133, \"functional effect\": -0.2603, \"times_seen\": 11.0}, {\"site\": 839, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": null, \"functional effect\": -3.0653, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": null, \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": null, \"functional effect\": 0.7771, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"C\", \"log2 fold change IC90\": -0.011695313146085023, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.0867379418346844, \"functional effect\": -0.6956, \"times_seen\": 4.0}, {\"site\": 839, \"mutant\": \"D\", \"log2 fold change IC90\": 0.03544914377725138, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.0896191887795041, \"functional effect\": -0.1825, \"times_seen\": 48.0}, {\"site\": 839, \"mutant\": \"E\", \"log2 fold change IC90\": 0.08316236513288619, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.09263265658585905, \"functional effect\": -0.054, \"times_seen\": 16.0}, {\"site\": 839, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 839, \"mutant\": \"N\", \"log2 fold change IC90\": 0.059800279153584796, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.09114470226458801, \"functional effect\": 0.1613, \"times_seen\": 17.0}, {\"site\": 839, \"mutant\": \"R\", \"log2 fold change IC90\": -0.134227307575235, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.07967522654594998, \"functional effect\": 0.4444, \"times_seen\": 21.0}, {\"site\": 839, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06155150873597026, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.08379168085348669, \"functional effect\": -0.0344, \"times_seen\": 21.0}, {\"site\": 839, \"mutant\": \"V\", \"log2 fold change IC90\": 0.08498870937431817, \"epitope\": \"all\", \"reference_site\": \"842\", \"IC90\": 0.09274999687150223, \"functional effect\": -0.1463, \"times_seen\": 48.0}, {\"site\": 840, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": null, \"functional effect\": -1.3064, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05069431614124464, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.09057122935043252, \"functional effect\": 0.0316, \"times_seen\": 8.0}, {\"site\": 840, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"E\", \"log2 fold change IC90\": 0.09008680926867954, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.09307833042886873, \"functional effect\": -0.0822, \"times_seen\": 5.0}, {\"site\": 840, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05337922795329976, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08426767353412695, \"functional effect\": 0.1265, \"times_seen\": 22.0}, {\"site\": 840, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": null, \"functional effect\": -3.2587, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0084339477181431, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08795663866140431, \"functional effect\": -0.8541, \"times_seen\": 23.0}, {\"site\": 840, \"mutant\": \"M\", \"log2 fold change IC90\": -0.10586786799206127, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.0812569185739703, \"functional effect\": -0.305, \"times_seen\": 12.0}, {\"site\": 840, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0538901389021603, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.09077208290278742, \"functional effect\": 0.0364, \"times_seen\": 62.0}, {\"site\": 840, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": null, \"functional effect\": -3.0689, \"times_seen\": null}, {\"site\": 840, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03467883146681654, \"epitope\": \"all\", \"reference_site\": \"843\", \"IC90\": 0.08536707170524303, \"functional effect\": -0.6549, \"times_seen\": 16.0}, {\"site\": 841, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0030835539302067074, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08725724778155391, \"functional effect\": -0.5269, \"times_seen\": 9.0}, {\"site\": 841, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 841, \"mutant\": \"L\", \"log2 fold change IC90\": 0.03787808710145418, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08977020009626503, \"functional effect\": -0.11, \"times_seen\": 6.0}, {\"site\": 841, \"mutant\": \"M\", \"log2 fold change IC90\": -0.06133771512106727, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08380409889975247, \"functional effect\": -0.1671, \"times_seen\": 31.0}, {\"site\": 841, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01796008806942685, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08853933954531107, \"functional effect\": -0.4068, \"times_seen\": 4.0}, {\"site\": 841, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02193872425501539, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08612426701723887, \"functional effect\": -0.8194, \"times_seen\": 8.0}, {\"site\": 841, \"mutant\": \"T\", \"log2 fold change IC90\": -0.10096741976937239, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.08153339583260003, \"functional effect\": -0.5731, \"times_seen\": 22.0}, {\"site\": 841, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05919475773951408, \"epitope\": \"all\", \"reference_site\": \"844\", \"IC90\": 0.0839286727371996, \"functional effect\": -0.1602, \"times_seen\": 26.0}, {\"site\": 842, \"mutant\": \"*\", \"log2 fold change IC90\": 0.049725250936605174, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.09051041264735678, \"functional effect\": -3.0735, \"times_seen\": 3.0}, {\"site\": 842, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 842, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005266474431347625, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.0871253199663315, \"functional effect\": -2.6345, \"times_seen\": 22.0}, {\"site\": 842, \"mutant\": \"D\", \"log2 fold change IC90\": 0.4254003893134552, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.11743242525511847, \"functional effect\": -1.1338, \"times_seen\": 60.0}, {\"site\": 842, \"mutant\": \"E\", \"log2 fold change IC90\": -0.19316266175135371, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.07648600853152919, \"functional effect\": -1.6906, \"times_seen\": 42.0}, {\"site\": 842, \"mutant\": \"F\", \"log2 fold change IC90\": -0.3935721574390583, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.06656604097259172, \"functional effect\": -1.4706, \"times_seen\": 24.0}, {\"site\": 842, \"mutant\": \"G\", \"log2 fold change IC90\": 0.005191082466510707, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08775915326783872, \"functional effect\": -0.2424, \"times_seen\": 131.0}, {\"site\": 842, \"mutant\": \"H\", \"log2 fold change IC90\": 0.6639012289207762, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.1385427924233597, \"functional effect\": -0.777, \"times_seen\": 25.0}, {\"site\": 842, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0328211603606913, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.0894560889154886, \"functional effect\": -1.1839, \"times_seen\": 41.0}, {\"site\": 842, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004220980079687879, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08718848095362865, \"functional effect\": -0.6403, \"times_seen\": 30.0}, {\"site\": 842, \"mutant\": \"L\", \"log2 fold change IC90\": -2.3120613738761366, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.017608806758352375, \"functional effect\": -1.7181, \"times_seen\": 72.0}, {\"site\": 842, \"mutant\": \"M\", \"log2 fold change IC90\": -0.08375351561279691, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08251206047779291, \"functional effect\": -1.1965, \"times_seen\": 30.0}, {\"site\": 842, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0406435547417289, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.08994244347899359, \"functional effect\": -0.9794, \"times_seen\": 41.0}, {\"site\": 842, \"mutant\": \"P\", \"log2 fold change IC90\": 0.06151202310986343, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.0912529087679891, \"functional effect\": -0.4868, \"times_seen\": 44.0}, {\"site\": 842, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.057148074881317276, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.09097729869027717, \"functional effect\": -0.9328, \"times_seen\": 33.0}, {\"site\": 842, \"mutant\": \"R\", \"log2 fold change IC90\": 0.5403941463030807, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.1271758357545125, \"functional effect\": -1.2054, \"times_seen\": 111.0}, {\"site\": 842, \"mutant\": \"S\", \"log2 fold change IC90\": 0.21879232564220039, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.10176368047441994, \"functional effect\": -0.5428, \"times_seen\": 157.0}, {\"site\": 842, \"mutant\": \"T\", \"log2 fold change IC90\": 0.5789983003398527, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.13062479102438065, \"functional effect\": -0.9665, \"times_seen\": 122.0}, {\"site\": 842, \"mutant\": \"V\", \"log2 fold change IC90\": 0.13858575483284066, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.09626052412057637, \"functional effect\": -0.9245, \"times_seen\": 183.0}, {\"site\": 842, \"mutant\": \"W\", \"log2 fold change IC90\": 0.09234034533831025, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.09322383538773174, \"functional effect\": -1.6397, \"times_seen\": 21.0}, {\"site\": 842, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.5230012882350891, \"epitope\": \"all\", \"reference_site\": \"845\", \"IC90\": 0.06085421678773995, \"functional effect\": -1.367, \"times_seen\": 24.0}, {\"site\": 843, \"mutant\": \"*\", \"log2 fold change IC90\": -0.028822934262004062, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.085714280716703, \"functional effect\": -2.5419, \"times_seen\": 10.0}, {\"site\": 843, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": null, \"functional effect\": -2.7207, \"times_seen\": null}, {\"site\": 843, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 843, \"mutant\": \"C\", \"log2 fold change IC90\": 0.04036583320928235, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08992513105437619, \"functional effect\": -2.79, \"times_seen\": 8.0}, {\"site\": 843, \"mutant\": \"D\", \"log2 fold change IC90\": -0.08593920590973185, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08238714893279252, \"functional effect\": -2.749, \"times_seen\": 29.0}, {\"site\": 843, \"mutant\": \"E\", \"log2 fold change IC90\": 0.03783841942364197, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08976773185015714, \"functional effect\": -2.0106, \"times_seen\": 29.0}, {\"site\": 843, \"mutant\": \"F\", \"log2 fold change IC90\": 2.2649914052190443, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.4203006926481999, \"functional effect\": -1.4673, \"times_seen\": 22.0}, {\"site\": 843, \"mutant\": \"G\", \"log2 fold change IC90\": 0.01308890088568647, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08824089504714014, \"functional effect\": -1.0724, \"times_seen\": 152.0}, {\"site\": 843, \"mutant\": \"H\", \"log2 fold change IC90\": 0.00956121123605235, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08802539127593498, \"functional effect\": -1.6658, \"times_seen\": 25.0}, {\"site\": 843, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04722086805759989, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.09035343137694785, \"functional effect\": -0.9476, \"times_seen\": 27.0}, {\"site\": 843, \"mutant\": \"K\", \"log2 fold change IC90\": 0.8896620944293177, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.1620110845240514, \"functional effect\": -2.8952, \"times_seen\": 15.0}, {\"site\": 843, \"mutant\": \"L\", \"log2 fold change IC90\": 0.5776199919545015, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.13050005553695496, \"functional effect\": -1.2763, \"times_seen\": 74.0}, {\"site\": 843, \"mutant\": \"M\", \"log2 fold change IC90\": -0.31285039788564556, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.07039671585179347, \"functional effect\": -1.2994, \"times_seen\": 27.0}, {\"site\": 843, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0010098432098080581, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08738276037586849, \"functional effect\": -2.338, \"times_seen\": 19.0}, {\"site\": 843, \"mutant\": \"P\", \"log2 fold change IC90\": -0.04116714445245754, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08498400763906214, \"functional effect\": -0.0578, \"times_seen\": 64.0}, {\"site\": 843, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.04350637724375882, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.0901210986266071, \"functional effect\": -1.8253, \"times_seen\": 23.0}, {\"site\": 843, \"mutant\": \"R\", \"log2 fold change IC90\": -0.1513799727503701, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.07873355119463844, \"functional effect\": -1.6611, \"times_seen\": 90.0}, {\"site\": 843, \"mutant\": \"S\", \"log2 fold change IC90\": -0.681558612495772, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.05452054225909359, \"functional effect\": -1.6539, \"times_seen\": 134.0}, {\"site\": 843, \"mutant\": \"T\", \"log2 fold change IC90\": -0.012861076462738475, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.08666788193584331, \"functional effect\": -1.208, \"times_seen\": 117.0}, {\"site\": 843, \"mutant\": \"V\", \"log2 fold change IC90\": 0.6396053686491947, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.13622918366420989, \"functional effect\": -0.3525, \"times_seen\": 118.0}, {\"site\": 843, \"mutant\": \"W\", \"log2 fold change IC90\": 0.6526553475754047, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.1374670425078435, \"functional effect\": -1.5017, \"times_seen\": 24.0}, {\"site\": 843, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.07927334489741289, \"epitope\": \"all\", \"reference_site\": \"846\", \"IC90\": 0.09238328638287574, \"functional effect\": -1.3419, \"times_seen\": 17.0}, {\"site\": 844, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04026347847018997, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.0850372560466871, \"functional effect\": -2.5694, \"times_seen\": 12.0}, {\"site\": 844, \"mutant\": \"I\", \"log2 fold change IC90\": -0.029083632011313098, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08569879338180841, \"functional effect\": -2.5871, \"times_seen\": 10.0}, {\"site\": 844, \"mutant\": \"K\", \"log2 fold change IC90\": -0.14879922355861405, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.07887451889033782, \"functional effect\": -0.6712, \"times_seen\": 39.0}, {\"site\": 844, \"mutant\": \"L\", \"log2 fold change IC90\": 0.05290495488671355, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.09071011784736965, \"functional effect\": -1.5409, \"times_seen\": 14.0}, {\"site\": 844, \"mutant\": \"M\", \"log2 fold change IC90\": 0.04973305355702869, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.09051090216196936, \"functional effect\": -1.2483, \"times_seen\": 4.0}, {\"site\": 844, \"mutant\": \"N\", \"log2 fold change IC90\": 0.04741704186790094, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.09036571823006417, \"functional effect\": -1.5557, \"times_seen\": 16.0}, {\"site\": 844, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 844, \"mutant\": \"S\", \"log2 fold change IC90\": 0.024571167933320284, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08894599779716061, \"functional effect\": -2.5772, \"times_seen\": 9.0}, {\"site\": 844, \"mutant\": \"T\", \"log2 fold change IC90\": -0.053332357582851805, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": 0.08427041127226456, \"functional effect\": -2.6551, \"times_seen\": 10.0}, {\"site\": 844, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"847\", \"IC90\": null, \"functional effect\": -1.9387, \"times_seen\": null}, {\"site\": 845, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 845, \"mutant\": \"E\", \"log2 fold change IC90\": 0.04807905019816324, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.09040719379078628, \"functional effect\": -2.2437, \"times_seen\": 31.0}, {\"site\": 845, \"mutant\": \"G\", \"log2 fold change IC90\": 0.6434494238173875, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.13659264979138933, \"functional effect\": -2.9922, \"times_seen\": 9.0}, {\"site\": 845, \"mutant\": \"N\", \"log2 fold change IC90\": 0.14344263037461297, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.09658513412119997, \"functional effect\": -2.7239, \"times_seen\": 27.0}, {\"site\": 845, \"mutant\": \"P\", \"log2 fold change IC90\": 0.16547834100131048, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.09807169854586462, \"functional effect\": -2.7619, \"times_seen\": 6.0}, {\"site\": 845, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0117828118947444, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.08673268138045616, \"functional effect\": -2.879, \"times_seen\": 5.0}, {\"site\": 845, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.002916849185175698, \"epitope\": \"all\", \"reference_site\": \"848\", \"IC90\": 0.08726733101971366, \"functional effect\": -2.8739, \"times_seen\": 2.0}, {\"site\": 846, \"mutant\": \"F\", \"log2 fold change IC90\": -0.034998095004332076, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.08534818235089209, \"functional effect\": -2.2632, \"times_seen\": 19.0}, {\"site\": 846, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0013033168034341492, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.0873649867481453, \"functional effect\": -2.4326, \"times_seen\": 10.0}, {\"site\": 846, \"mutant\": \"I\", \"log2 fold change IC90\": 0.08584030449104907, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.09280476157128607, \"functional effect\": -1.7226, \"times_seen\": 33.0}, {\"site\": 846, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 846, \"mutant\": \"M\", \"log2 fold change IC90\": 0.012022427606708368, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.08817568945640834, \"functional effect\": -1.5231, \"times_seen\": 36.0}, {\"site\": 846, \"mutant\": \"P\", \"log2 fold change IC90\": 0.4078166883704481, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": 0.11600983490823859, \"functional effect\": -2.7332, \"times_seen\": 32.0}, {\"site\": 846, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": null, \"functional effect\": -2.5052, \"times_seen\": null}, {\"site\": 846, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"849\", \"IC90\": null, \"functional effect\": -3.1951, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"F\", \"log2 fold change IC90\": -0.061176389675310146, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.0838134705889591, \"functional effect\": -0.5665, \"times_seen\": 15.0}, {\"site\": 847, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": null, \"functional effect\": -3.2539, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"L\", \"log2 fold change IC90\": -0.1306894407316093, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.0798708508735, \"functional effect\": -0.7579, \"times_seen\": 37.0}, {\"site\": 847, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": null, \"functional effect\": -2.5485, \"times_seen\": null}, {\"site\": 847, \"mutant\": \"N\", \"log2 fold change IC90\": -0.012672992249416178, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.086679181567817, \"functional effect\": -2.5023, \"times_seen\": 3.0}, {\"site\": 847, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00589728854887298, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08708723300650982, \"functional effect\": -1.3863, \"times_seen\": 1.0}, {\"site\": 847, \"mutant\": \"T\", \"log2 fold change IC90\": 0.02521172678897175, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08898549872795186, \"functional effect\": -1.5783, \"times_seen\": 7.0}, {\"site\": 847, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05369857600484073, \"epitope\": \"all\", \"reference_site\": \"850\", \"IC90\": 0.08424902251059495, \"functional effect\": -0.7984, \"times_seen\": 38.0}, {\"site\": 848, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.9615, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.5732, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012042117799065229, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.08671709369581575, \"functional effect\": -2.8686, \"times_seen\": 3.0}, {\"site\": 848, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0036996575383946044, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.08721999248760885, \"functional effect\": -2.9829, \"times_seen\": 2.0}, {\"site\": 848, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.4251, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -2.5641, \"times_seen\": null}, {\"site\": 848, \"mutant\": \"V\", \"log2 fold change IC90\": -0.002521257601048569, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": 0.0872912632813673, \"functional effect\": -3.064, \"times_seen\": 1.0}, {\"site\": 848, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"851\", \"IC90\": null, \"functional effect\": -3.0655, \"times_seen\": null}, {\"site\": 849, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 849, \"mutant\": \"D\", \"log2 fold change IC90\": -0.015789841615499706, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08649211894093532, \"functional effect\": -2.2183, \"times_seen\": 1.0}, {\"site\": 849, \"mutant\": \"G\", \"log2 fold change IC90\": 0.03237014115682146, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.0894281272833241, \"functional effect\": -1.4741, \"times_seen\": 16.0}, {\"site\": 849, \"mutant\": \"H\", \"log2 fold change IC90\": 0.001681963869690764, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08754595294220023, \"functional effect\": -1.7418, \"times_seen\": 12.0}, {\"site\": 849, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00236706354393324, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.08758753619115406, \"functional effect\": 0.1227, \"times_seen\": 6.0}, {\"site\": 849, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": null, \"functional effect\": -1.3309, \"times_seen\": null}, {\"site\": 849, \"mutant\": \"S\", \"log2 fold change IC90\": -0.14941842928221324, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.07884067315532584, \"functional effect\": -0.76, \"times_seen\": 32.0}, {\"site\": 849, \"mutant\": \"T\", \"log2 fold change IC90\": -0.8992079561886065, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.04688578434732354, \"functional effect\": -0.281, \"times_seen\": 62.0}, {\"site\": 849, \"mutant\": \"V\", \"log2 fold change IC90\": -0.15016289652458048, \"epitope\": \"all\", \"reference_site\": \"852\", \"IC90\": 0.07879999986291253, \"functional effect\": 0.0462, \"times_seen\": 58.0}, {\"site\": 850, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": null, \"functional effect\": -2.661, \"times_seen\": null}, {\"site\": 850, \"mutant\": \"E\", \"log2 fold change IC90\": -0.010142614571495618, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08683134367934253, \"functional effect\": -0.5227, \"times_seen\": 15.0}, {\"site\": 850, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0312798897640763, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08556843080149759, \"functional effect\": -0.1194, \"times_seen\": 16.0}, {\"site\": 850, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0164393393705476, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.0864531891656604, \"functional effect\": -1.3369, \"times_seen\": 24.0}, {\"site\": 850, \"mutant\": \"L\", \"log2 fold change IC90\": 0.023473105188851748, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.0888783250565517, \"functional effect\": -0.1023, \"times_seen\": 15.0}, {\"site\": 850, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": null, \"functional effect\": -1.5723, \"times_seen\": null}, {\"site\": 850, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 850, \"mutant\": \"R\", \"log2 fold change IC90\": -0.002947252832755875, \"epitope\": \"all\", \"reference_site\": \"853\", \"IC90\": 0.08726549194967802, \"functional effect\": -0.2598, \"times_seen\": 27.0}, {\"site\": 851, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0012430393978604109, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.0875193220775326, \"functional effect\": -1.312, \"times_seen\": 1.0}, {\"site\": 851, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01491797937862156, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08654440442104468, \"functional effect\": -2.41, \"times_seen\": 9.0}, {\"site\": 851, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 851, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 851, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01588799896943824, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08841226507089736, \"functional effect\": -2.0602, \"times_seen\": 20.0}, {\"site\": 851, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08673543875496267, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08234169147080667, \"functional effect\": -1.6936, \"times_seen\": 15.0}, {\"site\": 851, \"mutant\": \"R\", \"log2 fold change IC90\": -0.06577544666361794, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08354671346067385, \"functional effect\": -0.1584, \"times_seen\": 27.0}, {\"site\": 851, \"mutant\": \"S\", \"log2 fold change IC90\": -0.012002668574276487, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.0867194649307592, \"functional effect\": -2.4184, \"times_seen\": 3.0}, {\"site\": 851, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07404722975500269, \"epitope\": \"all\", \"reference_site\": \"854\", \"IC90\": 0.08306906373086051, \"functional effect\": -1.8308, \"times_seen\": 8.0}, {\"site\": 852, \"mutant\": \"C\", \"log2 fold change IC90\": -0.009609640133325499, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.08686342768514571, \"functional effect\": -2.5032, \"times_seen\": 1.0}, {\"site\": 852, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 852, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": null, \"functional effect\": -1.965, \"times_seen\": null}, {\"site\": 852, \"mutant\": \"L\", \"log2 fold change IC90\": -0.5216157747291661, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.06091268710619644, \"functional effect\": 0.3644, \"times_seen\": 38.0}, {\"site\": 852, \"mutant\": \"S\", \"log2 fold change IC90\": 0.08648468967150652, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.09284622242664572, \"functional effect\": -0.5995, \"times_seen\": 73.0}, {\"site\": 852, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": null, \"functional effect\": -2.4708, \"times_seen\": null}, {\"site\": 852, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0025357751496193574, \"epitope\": \"all\", \"reference_site\": \"855\", \"IC90\": 0.08729038489144944, \"functional effect\": -1.4274, \"times_seen\": 6.0}, {\"site\": 853, \"mutant\": \"*\", \"log2 fold change IC90\": 0.011624756033654588, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08815138762418348, \"functional effect\": -2.8102, \"times_seen\": 5.0}, {\"site\": 853, \"mutant\": \"-\", \"log2 fold change IC90\": 2.7220907867056026, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.5769799617149366, \"functional effect\": -0.5312, \"times_seen\": 1.0}, {\"site\": 853, \"mutant\": \"A\", \"log2 fold change IC90\": 0.6354822346270875, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.1358404048227576, \"functional effect\": -0.9125, \"times_seen\": 92.0}, {\"site\": 853, \"mutant\": \"C\", \"log2 fold change IC90\": 0.005123305935899956, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08775503051766956, \"functional effect\": -1.5977, \"times_seen\": 26.0}, {\"site\": 853, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010525891885254752, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08680827846955746, \"functional effect\": -2.5873, \"times_seen\": 3.0}, {\"site\": 853, \"mutant\": \"E\", \"log2 fold change IC90\": -0.027252888583430314, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.0858076120071841, \"functional effect\": -2.3979, \"times_seen\": 15.0}, {\"site\": 853, \"mutant\": \"F\", \"log2 fold change IC90\": -0.061676231885633294, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08378443725014267, \"functional effect\": -2.1267, \"times_seen\": 41.0}, {\"site\": 853, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0386882313303961, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.0851301570744777, \"functional effect\": -2.3544, \"times_seen\": 14.0}, {\"site\": 853, \"mutant\": \"H\", \"log2 fold change IC90\": -0.12715414930637284, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08006681258100462, \"functional effect\": 0.0791, \"times_seen\": 70.0}, {\"site\": 853, \"mutant\": \"I\", \"log2 fold change IC90\": 0.011856263289181488, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.0881655342890886, \"functional effect\": -2.1387, \"times_seen\": 18.0}, {\"site\": 853, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 853, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08078850456210726, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.0826818127377322, \"functional effect\": -2.0955, \"times_seen\": 61.0}, {\"site\": 853, \"mutant\": \"M\", \"log2 fold change IC90\": -0.5688420119327184, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.05895100921709257, \"functional effect\": -2.4447, \"times_seen\": 16.0}, {\"site\": 853, \"mutant\": \"N\", \"log2 fold change IC90\": 0.1606054755741504, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.09774100909345293, \"functional effect\": -1.7298, \"times_seen\": 64.0}, {\"site\": 853, \"mutant\": \"P\", \"log2 fold change IC90\": 0.006224603283167368, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.0878220448736143, \"functional effect\": -2.5298, \"times_seen\": 14.0}, {\"site\": 853, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.003318188439467428, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08764529902436832, \"functional effect\": -2.2424, \"times_seen\": 17.0}, {\"site\": 853, \"mutant\": \"R\", \"log2 fold change IC90\": 0.08886287307396915, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.09299939924512476, \"functional effect\": -0.6447, \"times_seen\": 224.0}, {\"site\": 853, \"mutant\": \"S\", \"log2 fold change IC90\": -0.5974412585980563, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.05779390148823013, \"functional effect\": -1.9095, \"times_seen\": 79.0}, {\"site\": 853, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0025994467795229727, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08728653251913297, \"functional effect\": -2.1544, \"times_seen\": 24.0}, {\"site\": 853, \"mutant\": \"V\", \"log2 fold change IC90\": -0.2526822560133912, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.07339471939181588, \"functional effect\": -0.8934, \"times_seen\": 83.0}, {\"site\": 853, \"mutant\": \"W\", \"log2 fold change IC90\": 0.03063675216056565, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.08932074447498836, \"functional effect\": -0.3892, \"times_seen\": 43.0}, {\"site\": 853, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.17040570073278857, \"epitope\": \"all\", \"reference_site\": \"856\", \"IC90\": 0.09840722385155419, \"functional effect\": -0.8007, \"times_seen\": 50.0}, {\"site\": 854, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005383269304773435, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08711826693118233, \"functional effect\": -2.1181, \"times_seen\": 1.0}, {\"site\": 854, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0009561614840743051, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08750192071154357, \"functional effect\": -2.9628, \"times_seen\": 2.0}, {\"site\": 854, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": null, \"functional effect\": -3.0382, \"times_seen\": null}, {\"site\": 854, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0012160315933910943, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08737027262055042, \"functional effect\": -1.1154, \"times_seen\": 1.0}, {\"site\": 854, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 854, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00513722393853011, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.08713312583983374, \"functional effect\": -2.289, \"times_seen\": 1.0}, {\"site\": 854, \"mutant\": \"S\", \"log2 fold change IC90\": -0.006105691078512748, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": 0.0870746538485119, \"functional effect\": -1.0823, \"times_seen\": 2.0}, {\"site\": 854, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"857\", \"IC90\": null, \"functional effect\": -3.0362, \"times_seen\": null}, {\"site\": 855, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0024801430601199804, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08759440163679663, \"functional effect\": -2.5774, \"times_seen\": 1.0}, {\"site\": 855, \"mutant\": \"F\", \"log2 fold change IC90\": -0.05318941593887801, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08427876116434015, \"functional effect\": -2.1564, \"times_seen\": 24.0}, {\"site\": 855, \"mutant\": \"H\", \"log2 fold change IC90\": 0.016338345847561688, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.0884398678570197, \"functional effect\": -2.7938, \"times_seen\": 2.0}, {\"site\": 855, \"mutant\": \"I\", \"log2 fold change IC90\": 0.03521635723211661, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08960472941163762, \"functional effect\": 0.4444, \"times_seen\": 39.0}, {\"site\": 855, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 855, \"mutant\": \"M\", \"log2 fold change IC90\": -0.012506947771912004, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08668915833163982, \"functional effect\": -0.3922, \"times_seen\": 3.0}, {\"site\": 855, \"mutant\": \"P\", \"log2 fold change IC90\": -0.00645568247530959, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.08705353248705604, \"functional effect\": -1.7526, \"times_seen\": 2.0}, {\"site\": 855, \"mutant\": \"V\", \"log2 fold change IC90\": 0.06470523517439271, \"epitope\": \"all\", \"reference_site\": \"858\", \"IC90\": 0.09145510853662525, \"functional effect\": -0.1563, \"times_seen\": 18.0}, {\"site\": 856, \"mutant\": \"*\", \"log2 fold change IC90\": -0.2112311175388487, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07553406374272505, \"functional effect\": -2.6513, \"times_seen\": 8.0}, {\"site\": 856, \"mutant\": \"A\", \"log2 fold change IC90\": -0.2299650871168029, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07455956467043104, \"functional effect\": -0.5444, \"times_seen\": 104.0}, {\"site\": 856, \"mutant\": \"C\", \"log2 fold change IC90\": -0.15694289478665474, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07843054518608036, \"functional effect\": -1.5342, \"times_seen\": 15.0}, {\"site\": 856, \"mutant\": \"D\", \"log2 fold change IC90\": -0.18236482299583986, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07706061504790405, \"functional effect\": -0.6204, \"times_seen\": 27.0}, {\"site\": 856, \"mutant\": \"E\", \"log2 fold change IC90\": 0.012028367410037993, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08817605249039484, \"functional effect\": -0.2778, \"times_seen\": 11.0}, {\"site\": 856, \"mutant\": \"F\", \"log2 fold change IC90\": -0.12212826793413588, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08034622578448232, \"functional effect\": -0.4182, \"times_seen\": 26.0}, {\"site\": 856, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07920533517887512, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08277259503024335, \"functional effect\": 0.4027, \"times_seen\": 39.0}, {\"site\": 856, \"mutant\": \"H\", \"log2 fold change IC90\": 0.30774823007719554, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.10823586721729472, \"functional effect\": -0.7925, \"times_seen\": 35.0}, {\"site\": 856, \"mutant\": \"I\", \"log2 fold change IC90\": -0.029743413359300246, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08565961009176516, \"functional effect\": -1.5402, \"times_seen\": 73.0}, {\"site\": 856, \"mutant\": \"K\", \"log2 fold change IC90\": 0.16610700674261913, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.09811444337443115, \"functional effect\": -2.407, \"times_seen\": 25.0}, {\"site\": 856, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0503169598244231, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.0905475423236322, \"functional effect\": -1.3142, \"times_seen\": 73.0}, {\"site\": 856, \"mutant\": \"M\", \"log2 fold change IC90\": 0.5341555576095284, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.12662708168696862, \"functional effect\": -1.0852, \"times_seen\": 36.0}, {\"site\": 856, \"mutant\": \"N\", \"log2 fold change IC90\": -0.05036538676063304, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08444389570087474, \"functional effect\": -0.2957, \"times_seen\": 82.0}, {\"site\": 856, \"mutant\": \"P\", \"log2 fold change IC90\": -0.026746362227749683, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.085837744118736, \"functional effect\": -2.7071, \"times_seen\": 11.0}, {\"site\": 856, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.04119787683539271, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08498219732352465, \"functional effect\": -1.4345, \"times_seen\": 27.0}, {\"site\": 856, \"mutant\": \"R\", \"log2 fold change IC90\": -0.22002405123638338, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.07507509901164815, \"functional effect\": -1.6237, \"times_seen\": 60.0}, {\"site\": 856, \"mutant\": \"S\", \"log2 fold change IC90\": -0.11318406457088295, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08084589148608305, \"functional effect\": -0.0987, \"times_seen\": 123.0}, {\"site\": 856, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 856, \"mutant\": \"V\", \"log2 fold change IC90\": 0.009137617023128451, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08799954965880133, \"functional effect\": -0.8602, \"times_seen\": 67.0}, {\"site\": 856, \"mutant\": \"W\", \"log2 fold change IC90\": -0.11605259348249293, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08068530427278559, \"functional effect\": -0.871, \"times_seen\": 23.0}, {\"site\": 856, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.063328534938372, \"epitope\": \"all\", \"reference_site\": \"859\", \"IC90\": 0.08368853476734972, \"functional effect\": -0.9994, \"times_seen\": 38.0}, {\"site\": 857, \"mutant\": \"A\", \"log2 fold change IC90\": -0.024201385362100557, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.0859892992722956, \"functional effect\": -0.6694, \"times_seen\": 6.0}, {\"site\": 857, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": null, \"functional effect\": -2.9421, \"times_seen\": null}, {\"site\": 857, \"mutant\": \"F\", \"log2 fold change IC90\": 0.4713765150929448, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.12123505759502964, \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 857, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0023434110585090896, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08730202467296216, \"functional effect\": 0.1868, \"times_seen\": 39.0}, {\"site\": 857, \"mutant\": \"L\", \"log2 fold change IC90\": -0.11140898826993793, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08094542461211952, \"functional effect\": 0.2905, \"times_seen\": 100.0}, {\"site\": 857, \"mutant\": \"M\", \"log2 fold change IC90\": -0.9670213344298513, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.044732927876891274, \"functional effect\": 0.4342, \"times_seen\": 18.0}, {\"site\": 857, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.09983960149712673, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.09370968275705531, \"functional effect\": -0.421, \"times_seen\": 16.0}, {\"site\": 857, \"mutant\": \"S\", \"log2 fold change IC90\": 0.006313893763430071, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.08782748047505007, \"functional effect\": -1.7347, \"times_seen\": 7.0}, {\"site\": 857, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"860\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0485777817945168, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.08454859273120528, \"functional effect\": -1.5722, \"times_seen\": 6.0}, {\"site\": 858, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"M\", \"log2 fold change IC90\": 0.06295085227277897, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.09134396255076638, \"functional effect\": -0.4802, \"times_seen\": 16.0}, {\"site\": 858, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": -2.1524, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": -3.2746, \"times_seen\": null}, {\"site\": 858, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04120013945276304, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": 0.08997714952933815, \"functional effect\": -1.3433, \"times_seen\": 13.0}, {\"site\": 858, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"861\", \"IC90\": null, \"functional effect\": -1.6898, \"times_seen\": null}, {\"site\": 859, \"mutant\": \"A\", \"log2 fold change IC90\": 0.1034002600588077, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.09394124956107967, \"functional effect\": -0.7611, \"times_seen\": 24.0}, {\"site\": 859, \"mutant\": \"H\", \"log2 fold change IC90\": -0.08401333865048302, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08249720175629287, \"functional effect\": -1.0231, \"times_seen\": 15.0}, {\"site\": 859, \"mutant\": \"K\", \"log2 fold change IC90\": -0.006121250717208293, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08707371474301216, \"functional effect\": -1.3384, \"times_seen\": 3.0}, {\"site\": 859, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009553465055590312, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08686681000411449, \"functional effect\": -1.0846, \"times_seen\": 4.0}, {\"site\": 859, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 859, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.013976236169266094, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.0882951846519991, \"functional effect\": -0.919, \"times_seen\": 5.0}, {\"site\": 859, \"mutant\": \"S\", \"log2 fold change IC90\": -0.030581361948612433, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08560987157722999, \"functional effect\": -1.0717, \"times_seen\": 33.0}, {\"site\": 859, \"mutant\": \"T\", \"log2 fold change IC90\": -0.024278545205415423, \"epitope\": \"all\", \"reference_site\": \"862\", \"IC90\": 0.08598470041859085, \"functional effect\": -0.7747, \"times_seen\": 17.0}, {\"site\": 860, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01645117692461238, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.0864524798056964, \"functional effect\": -1.96, \"times_seen\": 5.0}, {\"site\": 860, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06531555240978708, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.08357335025991965, \"functional effect\": -2.6658, \"times_seen\": 8.0}, {\"site\": 860, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 860, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0015318622370163438, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.08735114786552498, \"functional effect\": -0.6719, \"times_seen\": 1.0}, {\"site\": 860, \"mutant\": \"S\", \"log2 fold change IC90\": -0.15744999552375116, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.07840298205104818, \"functional effect\": -0.9811, \"times_seen\": 17.0}, {\"site\": 860, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004760340350363778, \"epitope\": \"all\", \"reference_site\": \"863\", \"IC90\": 0.08715589110478884, \"functional effect\": -2.9445, \"times_seen\": 1.0}, {\"site\": 861, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": null, \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 861, \"mutant\": \"F\", \"log2 fold change IC90\": 0.04192932400063371, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.09002263837398132, \"functional effect\": -2.6214, \"times_seen\": 5.0}, {\"site\": 861, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 861, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01634828448955289, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.08645864578195916, \"functional effect\": -1.0673, \"times_seen\": 2.0}, {\"site\": 861, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": null, \"functional effect\": -2.7403, \"times_seen\": null}, {\"site\": 861, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.014674231238274162, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.08655902762218978, \"functional effect\": -0.7441, \"times_seen\": 4.0}, {\"site\": 861, \"mutant\": \"V\", \"log2 fold change IC90\": 0.003811529916458677, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.08767527518278437, \"functional effect\": -1.5503, \"times_seen\": 13.0}, {\"site\": 861, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01365661937924375, \"epitope\": \"all\", \"reference_site\": \"864\", \"IC90\": 0.08662010398474686, \"functional effect\": -2.7774, \"times_seen\": 3.0}, {\"site\": 862, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -2.6718, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"C\", \"log2 fold change IC90\": 0.006691108563635794, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08785044732257469, \"functional effect\": -2.018, \"times_seen\": 5.0}, {\"site\": 862, \"mutant\": \"F\", \"log2 fold change IC90\": 0.013932425568344658, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08829250341566373, \"functional effect\": -0.432, \"times_seen\": 24.0}, {\"site\": 862, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"M\", \"log2 fold change IC90\": -0.004058344867527511, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08719831027720568, \"functional effect\": -0.1443, \"times_seen\": 3.0}, {\"site\": 862, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -2.9684, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.019178155869582502, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": 0.08628922186490844, \"functional effect\": -1.6943, \"times_seen\": 1.0}, {\"site\": 862, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -1.8793, \"times_seen\": null}, {\"site\": 862, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"865\", \"IC90\": null, \"functional effect\": -2.3348, \"times_seen\": null}, {\"site\": 863, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": null, \"functional effect\": -2.0678, \"times_seen\": null}, {\"site\": 863, \"mutant\": \"A\", \"log2 fold change IC90\": -0.011355803205514457, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08675835630757375, \"functional effect\": -1.8864, \"times_seen\": 4.0}, {\"site\": 863, \"mutant\": \"C\", \"log2 fold change IC90\": -0.008350750044368336, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08693925745431792, \"functional effect\": -2.383, \"times_seen\": 2.0}, {\"site\": 863, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004628181082331194, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08716387545771287, \"functional effect\": -1.4373, \"times_seen\": 1.0}, {\"site\": 863, \"mutant\": \"F\", \"log2 fold change IC90\": -0.003699452952556602, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08722000485611087, \"functional effect\": -3.0869, \"times_seen\": 1.0}, {\"site\": 863, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005663243157298202, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08710136213176226, \"functional effect\": -2.9688, \"times_seen\": 2.0}, {\"site\": 863, \"mutant\": \"K\", \"log2 fold change IC90\": 0.08071912442442596, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.0924759135898593, \"functional effect\": -0.8521, \"times_seen\": 4.0}, {\"site\": 863, \"mutant\": \"N\", \"log2 fold change IC90\": -0.039641740697117414, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08507391124189131, \"functional effect\": -0.8765, \"times_seen\": 21.0}, {\"site\": 863, \"mutant\": \"S\", \"log2 fold change IC90\": 0.012509353106701584, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.08820545474761039, \"functional effect\": -1.2687, \"times_seen\": 6.0}, {\"site\": 863, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"866\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": null, \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"A\", \"log2 fold change IC90\": -0.012627197539540424, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08668193302315605, \"functional effect\": -1.1439, \"times_seen\": 5.0}, {\"site\": 864, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"E\", \"log2 fold change IC90\": -0.16926459015843387, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.07776354203978396, \"functional effect\": -1.6771, \"times_seen\": 15.0}, {\"site\": 864, \"mutant\": \"G\", \"log2 fold change IC90\": 0.042631315227306676, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.09006645253974871, \"functional effect\": -0.9305, \"times_seen\": 25.0}, {\"site\": 864, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"N\", \"log2 fold change IC90\": -0.09302138661023479, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08198370201657139, \"functional effect\": -0.5879, \"times_seen\": 47.0}, {\"site\": 864, \"mutant\": \"S\", \"log2 fold change IC90\": -0.015371115166692569, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08651722597535545, \"functional effect\": -0.928, \"times_seen\": 6.0}, {\"site\": 864, \"mutant\": \"T\", \"log2 fold change IC90\": 0.03972336714639333, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08988509419201166, \"functional effect\": -1.4787, \"times_seen\": 7.0}, {\"site\": 864, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": null, \"functional effect\": -2.9937, \"times_seen\": null}, {\"site\": 864, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.12118906803118688, \"epitope\": \"all\", \"reference_site\": \"867\", \"IC90\": 0.08039854850924587, \"functional effect\": -1.1107, \"times_seen\": 51.0}, {\"site\": 865, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": null, \"functional effect\": -2.9627, \"times_seen\": null}, {\"site\": 865, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": null, \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 865, \"mutant\": \"A\", \"log2 fold change IC90\": -0.005906901146077452, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08708665275102967, \"functional effect\": 0.4116, \"times_seen\": 11.0}, {\"site\": 865, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0033430126574774816, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08764680713569308, \"functional effect\": -0.8784, \"times_seen\": 12.0}, {\"site\": 865, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 865, \"mutant\": \"G\", \"log2 fold change IC90\": -1.0024228816679326, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.04364860789416175, \"functional effect\": -0.0776, \"times_seen\": 23.0}, {\"site\": 865, \"mutant\": \"K\", \"log2 fold change IC90\": -0.10134091710164524, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.0815122904961234, \"functional effect\": -0.8603, \"times_seen\": 28.0}, {\"site\": 865, \"mutant\": \"L\", \"log2 fold change IC90\": -0.031144050182956077, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.0855764880323777, \"functional effect\": -0.0227, \"times_seen\": 19.0}, {\"site\": 865, \"mutant\": \"Q\", \"log2 fold change IC90\": 1.12342051568928, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.19050791580928297, \"functional effect\": -0.1754, \"times_seen\": 16.0}, {\"site\": 865, \"mutant\": \"S\", \"log2 fold change IC90\": 0.07699652029025203, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.09223760441682942, \"functional effect\": 0.0639, \"times_seen\": 11.0}, {\"site\": 865, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03452024754374938, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.08537645594018446, \"functional effect\": -0.2828, \"times_seen\": 10.0}, {\"site\": 865, \"mutant\": \"V\", \"log2 fold change IC90\": -0.07367442712688668, \"epitope\": \"all\", \"reference_site\": \"868\", \"IC90\": 0.0830905321396118, \"functional effect\": -0.0615, \"times_seen\": 19.0}, {\"site\": 866, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": null, \"functional effect\": -1.4639, \"times_seen\": null}, {\"site\": 866, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02775455337678711, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08914247869493264, \"functional effect\": -1.9106, \"times_seen\": 5.0}, {\"site\": 866, \"mutant\": \"I\", \"log2 fold change IC90\": 0.007481613615057273, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08789859696608185, \"functional effect\": -2.1834, \"times_seen\": 43.0}, {\"site\": 866, \"mutant\": \"K\", \"log2 fold change IC90\": -0.001590013413024688, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.0873476270454906, \"functional effect\": -2.8871, \"times_seen\": 1.0}, {\"site\": 866, \"mutant\": \"L\", \"log2 fold change IC90\": -0.020213627855234593, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.0862273113348038, \"functional effect\": -1.9617, \"times_seen\": 13.0}, {\"site\": 866, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 866, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": null, \"functional effect\": -1.1256, \"times_seen\": null}, {\"site\": 866, \"mutant\": \"T\", \"log2 fold change IC90\": -0.010423311524539807, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": 0.08681445104300835, \"functional effect\": -2.0013, \"times_seen\": 2.0}, {\"site\": 866, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"869\", \"IC90\": null, \"functional effect\": -1.6846, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"A\", \"log2 fold change IC90\": -0.006777712678179927, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08703410305991768, \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 867, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": null, \"functional effect\": -3.029, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"K\", \"log2 fold change IC90\": -0.055392101404017305, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08415018377745344, \"functional effect\": -2.5393, \"times_seen\": 18.0}, {\"site\": 867, \"mutant\": \"L\", \"log2 fold change IC90\": -0.003305778121050347, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08724380822752578, \"functional effect\": -0.2995, \"times_seen\": 8.0}, {\"site\": 867, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": null, \"functional effect\": -1.3361, \"times_seen\": null}, {\"site\": 867, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01320627641096343, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08824807448732194, \"functional effect\": -2.73, \"times_seen\": 3.0}, {\"site\": 867, \"mutant\": \"S\", \"log2 fold change IC90\": 0.062343449428617824, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.0913055130495963, \"functional effect\": -1.9914, \"times_seen\": 7.0}, {\"site\": 867, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03682605292644486, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.08524011093885302, \"functional effect\": -1.265, \"times_seen\": 16.0}, {\"site\": 867, \"mutant\": \"V\", \"log2 fold change IC90\": -0.8865023673246979, \"epitope\": \"all\", \"reference_site\": \"870\", \"IC90\": 0.04730052368514007, \"functional effect\": -0.5048, \"times_seen\": 13.0}, {\"site\": 868, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0432346148537352, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.09010412399381608, \"functional effect\": -0.8446, \"times_seen\": 16.0}, {\"site\": 868, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": null, \"functional effect\": -2.4325, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": null, \"functional effect\": -1.963, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01052333100594478, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.08680843256014159, \"functional effect\": -2.239, \"times_seen\": 8.0}, {\"site\": 868, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": null, \"functional effect\": -1.1637, \"times_seen\": null}, {\"site\": 868, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04025481801058968, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.08503776652458446, \"functional effect\": -1.8396, \"times_seen\": 40.0}, {\"site\": 868, \"mutant\": \"T\", \"log2 fold change IC90\": -0.09066014493150945, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.08211799362561563, \"functional effect\": -1.8136, \"times_seen\": 42.0}, {\"site\": 868, \"mutant\": \"V\", \"log2 fold change IC90\": 0.7060994762457881, \"epitope\": \"all\", \"reference_site\": \"871\", \"IC90\": 0.142654959594483, \"functional effect\": -0.9823, \"times_seen\": 63.0}, {\"site\": 869, \"mutant\": \"*\", \"log2 fold change IC90\": -0.013080421046625315, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08665470611912376, \"functional effect\": -1.2791, \"times_seen\": 1.0}, {\"site\": 869, \"mutant\": \"H\", \"log2 fold change IC90\": -0.021105121217528375, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08617404482475835, \"functional effect\": -2.6765, \"times_seen\": 18.0}, {\"site\": 869, \"mutant\": \"K\", \"log2 fold change IC90\": 0.026672360446324796, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.0890756363028743, \"functional effect\": -2.8286, \"times_seen\": 14.0}, {\"site\": 869, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01224302836102177, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08818917332534305, \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 869, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 869, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004431667036239235, \"epitope\": \"all\", \"reference_site\": \"872\", \"IC90\": 0.08717574913302141, \"functional effect\": -2.8946, \"times_seen\": 11.0}, {\"site\": 870, \"mutant\": \"*\", \"log2 fold change IC90\": 0.031239848867476726, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08935809145855826, \"functional effect\": -2.8302, \"times_seen\": 2.0}, {\"site\": 870, \"mutant\": \"C\", \"log2 fold change IC90\": 0.016531756789461432, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08845172509939836, \"functional effect\": -2.2976, \"times_seen\": 5.0}, {\"site\": 870, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": null, \"functional effect\": -3.2859, \"times_seen\": null}, {\"site\": 870, \"mutant\": \"H\", \"log2 fold change IC90\": -0.026291176197600633, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08586483113668969, \"functional effect\": -2.5511, \"times_seen\": 4.0}, {\"site\": 870, \"mutant\": \"L\", \"log2 fold change IC90\": -0.013096938442130588, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08665371401627507, \"functional effect\": -2.6485, \"times_seen\": 3.0}, {\"site\": 870, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": null, \"functional effect\": -2.3176, \"times_seen\": null}, {\"site\": 870, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": null, \"functional effect\": -3.0674, \"times_seen\": null}, {\"site\": 870, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03020094479755016, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.08929376666044817, \"functional effect\": -2.876, \"times_seen\": 3.0}, {\"site\": 870, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"873\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 871, \"mutant\": \"A\", \"log2 fold change IC90\": 0.03450463660801188, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08956053586822663, \"functional effect\": -1.3152, \"times_seen\": 28.0}, {\"site\": 871, \"mutant\": \"I\", \"log2 fold change IC90\": -1.0860245520099077, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.041191137633354455, \"functional effect\": -0.4757, \"times_seen\": 60.0}, {\"site\": 871, \"mutant\": \"L\", \"log2 fold change IC90\": -0.008356047813969874, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08693893820229542, \"functional effect\": -2.4712, \"times_seen\": 2.0}, {\"site\": 871, \"mutant\": \"N\", \"log2 fold change IC90\": -0.07441935841509971, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08304763966542747, \"functional effect\": -2.4005, \"times_seen\": 26.0}, {\"site\": 871, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": null, \"functional effect\": -0.2002, \"times_seen\": null}, {\"site\": 871, \"mutant\": \"S\", \"log2 fold change IC90\": 0.002186997375444354, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08757660486651439, \"functional effect\": -0.8241, \"times_seen\": 13.0}, {\"site\": 871, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 871, \"mutant\": \"V\", \"log2 fold change IC90\": -0.006220410689022745, \"epitope\": \"all\", \"reference_site\": \"874\", \"IC90\": 0.08706773015851164, \"functional effect\": -0.5853, \"times_seen\": 10.0}, {\"site\": 872, \"mutant\": \"A\", \"log2 fold change IC90\": -0.047635256869183636, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08460384709214964, \"functional effect\": 0.4444, \"times_seen\": 17.0}, {\"site\": 872, \"mutant\": \"D\", \"log2 fold change IC90\": -0.00407307691037165, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08719741985847707, \"functional effect\": -2.9798, \"times_seen\": 5.0}, {\"site\": 872, \"mutant\": \"F\", \"log2 fold change IC90\": 0.00313474390818448, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08763415527728968, \"functional effect\": -2.3565, \"times_seen\": 7.0}, {\"site\": 872, \"mutant\": \"P\", \"log2 fold change IC90\": -0.022918642012282265, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08606578893206486, \"functional effect\": -2.6843, \"times_seen\": 5.0}, {\"site\": 872, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.015518660240654465, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08838963388883846, \"functional effect\": -2.8007, \"times_seen\": 6.0}, {\"site\": 872, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 872, \"mutant\": \"T\", \"log2 fold change IC90\": -0.024577454645930284, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08596688724559734, \"functional effect\": -1.976, \"times_seen\": 7.0}, {\"site\": 872, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005705275333263872, \"epitope\": \"all\", \"reference_site\": \"875\", \"IC90\": 0.08709882451546416, \"functional effect\": -2.1349, \"times_seen\": 4.0}, {\"site\": 873, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 873, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0024240761980415053, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.08729714350755274, \"functional effect\": -1.8838, \"times_seen\": 3.0}, {\"site\": 873, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": null, \"functional effect\": -2.9101, \"times_seen\": null}, {\"site\": 873, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": null, \"functional effect\": -2.995, \"times_seen\": null}, {\"site\": 873, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06185418745302027, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.08377410312746236, \"functional effect\": 0.4444, \"times_seen\": 22.0}, {\"site\": 873, \"mutant\": \"T\", \"log2 fold change IC90\": 0.002246317324388087, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.0875802058676872, \"functional effect\": -1.912, \"times_seen\": 18.0}, {\"site\": 873, \"mutant\": \"V\", \"log2 fold change IC90\": 1.0517725923821635, \"epitope\": \"all\", \"reference_site\": \"876\", \"IC90\": 0.1812778959306181, \"functional effect\": -2.9086, \"times_seen\": 20.0}, {\"site\": 874, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 874, \"mutant\": \"M\", \"log2 fold change IC90\": -0.3789181216365736, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": 0.06724562467693604, \"functional effect\": -0.3375, \"times_seen\": 23.0}, {\"site\": 874, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": null, \"functional effect\": -2.9952, \"times_seen\": null}, {\"site\": 874, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": null, \"functional effect\": -1.8158, \"times_seen\": null}, {\"site\": 874, \"mutant\": \"T\", \"log2 fold change IC90\": -0.11829676638131081, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": 0.0805598924506996, \"functional effect\": -2.0821, \"times_seen\": 4.0}, {\"site\": 874, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"877\", \"IC90\": null, \"functional effect\": -1.083, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": null, \"functional effect\": -2.1864, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05392789763455887, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.08423563188598188, \"functional effect\": -0.2397, \"times_seen\": 19.0}, {\"site\": 875, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"M\", \"log2 fold change IC90\": -0.006289194076783086, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.08706357912831256, \"functional effect\": 0.193, \"times_seen\": 2.0}, {\"site\": 875, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": null, \"functional effect\": -1.5423, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": null, \"functional effect\": -3.0457, \"times_seen\": null}, {\"site\": 875, \"mutant\": \"S\", \"log2 fold change IC90\": 0.10761243531170925, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.0942159266119005, \"functional effect\": -1.6517, \"times_seen\": 15.0}, {\"site\": 875, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03714189515586638, \"epitope\": \"all\", \"reference_site\": \"878\", \"IC90\": 0.08522145177726377, \"functional effect\": -0.3973, \"times_seen\": 17.0}, {\"site\": 876, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 876, \"mutant\": \"C\", \"log2 fold change IC90\": 0.04006378234440739, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08990630578663367, \"functional effect\": -1.3348, \"times_seen\": 5.0}, {\"site\": 876, \"mutant\": \"D\", \"log2 fold change IC90\": -0.014819272369105282, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08655032586067614, \"functional effect\": -2.5662, \"times_seen\": 3.0}, {\"site\": 876, \"mutant\": \"F\", \"log2 fold change IC90\": -0.07919389456548241, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08277325142191808, \"functional effect\": -1.8807, \"times_seen\": 5.0}, {\"site\": 876, \"mutant\": \"G\", \"log2 fold change IC90\": -0.017243279534249843, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08640502664524494, \"functional effect\": -2.1241, \"times_seen\": 11.0}, {\"site\": 876, \"mutant\": \"H\", \"log2 fold change IC90\": 0.20261649271935472, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.10062905510815738, \"functional effect\": -2.8638, \"times_seen\": 6.0}, {\"site\": 876, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": null, \"functional effect\": -3.1006, \"times_seen\": null}, {\"site\": 876, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02880264548551077, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08571548613438496, \"functional effect\": -0.6351, \"times_seen\": 23.0}, {\"site\": 876, \"mutant\": \"T\", \"log2 fold change IC90\": -0.13428302598714126, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.0796721494636561, \"functional effect\": -1.6446, \"times_seen\": 62.0}, {\"site\": 876, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011602731560163415, \"epitope\": \"all\", \"reference_site\": \"879\", \"IC90\": 0.08674350821819345, \"functional effect\": -0.8753, \"times_seen\": 50.0}, {\"site\": 877, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": null, \"functional effect\": -1.703, \"times_seen\": null}, {\"site\": 877, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01884974397871982, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08630886678736338, \"functional effect\": -2.5512, \"times_seen\": 5.0}, {\"site\": 877, \"mutant\": \"D\", \"log2 fold change IC90\": 0.025613011818979233, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08901025345028372, \"functional effect\": -2.8455, \"times_seen\": 4.0}, {\"site\": 877, \"mutant\": \"F\", \"log2 fold change IC90\": 0.04297208798738859, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.09008772925996567, \"functional effect\": -2.9677, \"times_seen\": 4.0}, {\"site\": 877, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 877, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": null, \"functional effect\": -3.1228, \"times_seen\": null}, {\"site\": 877, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005013601047085605, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08714059249783834, \"functional effect\": -2.2973, \"times_seen\": 1.0}, {\"site\": 877, \"mutant\": \"V\", \"log2 fold change IC90\": -0.00607792886186024, \"epitope\": \"all\", \"reference_site\": \"880\", \"IC90\": 0.08707632946851195, \"functional effect\": -2.0185, \"times_seen\": 2.0}, {\"site\": 878, \"mutant\": \"A\", \"log2 fold change IC90\": 0.6735008573851391, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.13946772379920433, \"functional effect\": -1.2638, \"times_seen\": 35.0}, {\"site\": 878, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0934954615362871, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.09329850638910574, \"functional effect\": -1.4343, \"times_seen\": 13.0}, {\"site\": 878, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0062303521826648535, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.08706713018396474, \"functional effect\": -0.3877, \"times_seen\": 36.0}, {\"site\": 878, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 878, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0024422027555979016, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.08729604668063466, \"functional effect\": -2.9447, \"times_seen\": 2.0}, {\"site\": 878, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0012513044555631184, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.08751982346853943, \"functional effect\": -2.7151, \"times_seen\": 2.0}, {\"site\": 878, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"881\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": null, \"functional effect\": -2.8883, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"L\", \"log2 fold change IC90\": 0.004825213211507949, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.08773690025933867, \"functional effect\": -0.3617, \"times_seen\": 15.0}, {\"site\": 879, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": null, \"functional effect\": -3.1585, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": null, \"functional effect\": -3.3372, \"times_seen\": null}, {\"site\": 879, \"mutant\": \"T\", \"log2 fold change IC90\": -0.016529701799527834, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.08644777438617075, \"functional effect\": -2.4807, \"times_seen\": 4.0}, {\"site\": 879, \"mutant\": \"V\", \"log2 fold change IC90\": 0.028645453465130696, \"epitope\": \"all\", \"reference_site\": \"882\", \"IC90\": 0.08919754339394459, \"functional effect\": -1.8263, \"times_seen\": 23.0}, {\"site\": 880, \"mutant\": \"A\", \"log2 fold change IC90\": 0.11613906661952067, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.09477441132138395, \"functional effect\": -2.1703, \"times_seen\": 16.0}, {\"site\": 880, \"mutant\": \"I\", \"log2 fold change IC90\": -0.7053550651924348, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.05362863222441949, \"functional effect\": 0.1604, \"times_seen\": 66.0}, {\"site\": 880, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005717518677487876, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08709808535969323, \"functional effect\": -1.9154, \"times_seen\": 1.0}, {\"site\": 880, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.002513299700393596, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08729174478098947, \"functional effect\": -2.556, \"times_seen\": 5.0}, {\"site\": 880, \"mutant\": \"S\", \"log2 fold change IC90\": 0.014293074647842973, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08831457779005779, \"functional effect\": -2.1828, \"times_seen\": 34.0}, {\"site\": 880, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 880, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03629785147981391, \"epitope\": \"all\", \"reference_site\": \"883\", \"IC90\": 0.08967192540814392, \"functional effect\": 0.3069, \"times_seen\": 16.0}, {\"site\": 881, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0014313387298106445, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08753074577063913, \"functional effect\": -0.6929, \"times_seen\": 17.0}, {\"site\": 881, \"mutant\": \"C\", \"log2 fold change IC90\": 0.2760642190050401, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.10588473730135137, \"functional effect\": -0.0416, \"times_seen\": 71.0}, {\"site\": 881, \"mutant\": \"F\", \"log2 fold change IC90\": 0.016747172895822084, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.0884649332607018, \"functional effect\": -0.9622, \"times_seen\": 58.0}, {\"site\": 881, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0024118078395088506, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08729788586624868, \"functional effect\": -3.0951, \"times_seen\": 3.0}, {\"site\": 881, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.012566023847282443, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08820891962860061, \"functional effect\": -2.5014, \"times_seen\": 5.0}, {\"site\": 881, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 881, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003145233011968123, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.08725351737996316, \"functional effect\": 0.2088, \"times_seen\": 1.0}, {\"site\": 881, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.022534317534874792, \"epitope\": \"all\", \"reference_site\": \"884\", \"IC90\": 0.0860887193467267, \"functional effect\": -0.6158, \"times_seen\": 5.0}, {\"site\": 882, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": null, \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 882, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": null, \"functional effect\": -2.766, \"times_seen\": null}, {\"site\": 882, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0557874604036578, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.09089153789304158, \"functional effect\": -1.9734, \"times_seen\": 12.0}, {\"site\": 882, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04566773771402443, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.08471930686977248, \"functional effect\": 0.3778, \"times_seen\": 18.0}, {\"site\": 882, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 882, \"mutant\": \"K\", \"log2 fold change IC90\": -0.014918011115502599, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.08654440251721236, \"functional effect\": -2.6946, \"times_seen\": 3.0}, {\"site\": 882, \"mutant\": \"S\", \"log2 fold change IC90\": -0.053789284460343374, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.0842437255779431, \"functional effect\": -1.3894, \"times_seen\": 10.0}, {\"site\": 882, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0043412227384383205, \"epitope\": \"all\", \"reference_site\": \"885\", \"IC90\": 0.08770747151615663, \"functional effect\": -1.2089, \"times_seen\": 5.0}, {\"site\": 883, \"mutant\": \"*\", \"log2 fold change IC90\": -0.026156100967823875, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08587287078085337, \"functional effect\": -2.5819, \"times_seen\": 6.0}, {\"site\": 883, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": null, \"functional effect\": -3.2373, \"times_seen\": null}, {\"site\": 883, \"mutant\": \"C\", \"log2 fold change IC90\": -0.06816341238262394, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08340854034702971, \"functional effect\": -0.9062, \"times_seen\": 10.0}, {\"site\": 883, \"mutant\": \"F\", \"log2 fold change IC90\": 0.012038097945096362, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08817664721279925, \"functional effect\": 0.0434, \"times_seen\": 2.0}, {\"site\": 883, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": null, \"functional effect\": -0.9736, \"times_seen\": null}, {\"site\": 883, \"mutant\": \"L\", \"log2 fold change IC90\": -0.4112856294457403, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.06575373720219885, \"functional effect\": 0.0778, \"times_seen\": 29.0}, {\"site\": 883, \"mutant\": \"R\", \"log2 fold change IC90\": -0.06228305244845235, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08374920358888895, \"functional effect\": -2.9759, \"times_seen\": 16.0}, {\"site\": 883, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 883, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0013378680656191005, \"epitope\": \"all\", \"reference_site\": \"886\", \"IC90\": 0.08752507493121635, \"functional effect\": -0.2983, \"times_seen\": 9.0}, {\"site\": 884, \"mutant\": \"-\", \"log2 fold change IC90\": -0.055509685381842554, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08414332556428337, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 884, \"mutant\": \"A\", \"log2 fold change IC90\": -0.015252881893420276, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08652431661731426, \"functional effect\": -1.8786, \"times_seen\": 10.0}, {\"site\": 884, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06741727268439306, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.08345168911893117, \"functional effect\": -2.6117, \"times_seen\": 19.0}, {\"site\": 884, \"mutant\": \"L\", \"log2 fold change IC90\": 0.011855911305853726, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.0881655127787947, \"functional effect\": -2.7934, \"times_seen\": 2.0}, {\"site\": 884, \"mutant\": \"N\", \"log2 fold change IC90\": -1.809913195898494, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.024939721033387065, \"functional effect\": -2.577, \"times_seen\": 13.0}, {\"site\": 884, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": null, \"functional effect\": -2.0907, \"times_seen\": null}, {\"site\": 884, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"887\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"-\", \"log2 fold change IC90\": -0.09667424356955027, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08177638451868463, \"functional effect\": 0.3901, \"times_seen\": 19.0}, {\"site\": 885, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004534350279872823, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08716954465467934, \"functional effect\": -1.1316, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"C\", \"log2 fold change IC90\": -0.004920323526636122, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08714622675937003, \"functional effect\": -0.635, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": null, \"functional effect\": -2.771, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"G\", \"log2 fold change IC90\": -0.009106218469123071, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.086893743559585, \"functional effect\": -0.454, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0021596986168024596, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08731314239976838, \"functional effect\": -0.1789, \"times_seen\": 31.0}, {\"site\": 885, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08404183590430273, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08249557222239101, \"functional effect\": -1.6337, \"times_seen\": 33.0}, {\"site\": 885, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": null, \"functional effect\": -3.2601, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0033554493228426115, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08724080452259748, \"functional effect\": -3.006, \"times_seen\": 1.0}, {\"site\": 885, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": null, \"functional effect\": -1.3239, \"times_seen\": null}, {\"site\": 885, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0035797034025408314, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08722724477135294, \"functional effect\": -0.3042, \"times_seen\": 20.0}, {\"site\": 885, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010453424662487804, \"epitope\": \"all\", \"reference_site\": \"888\", \"IC90\": 0.08681263899806275, \"functional effect\": -0.2256, \"times_seen\": 3.0}, {\"site\": 886, \"mutant\": \"*\", \"log2 fold change IC90\": 0.042126606481022795, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.09003494943296235, \"functional effect\": -2.8258, \"times_seen\": 2.0}, {\"site\": 886, \"mutant\": \"-\", \"log2 fold change IC90\": -0.04452781991442035, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08478627265661777, \"functional effect\": -1.119, \"times_seen\": 15.0}, {\"site\": 886, \"mutant\": \"E\", \"log2 fold change IC90\": 0.00132534577202276, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08752431523502435, \"functional effect\": -2.6001, \"times_seen\": 2.0}, {\"site\": 886, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 886, \"mutant\": \"L\", \"log2 fold change IC90\": 0.020316189889740197, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.0886840535196309, \"functional effect\": -3.051, \"times_seen\": 2.0}, {\"site\": 886, \"mutant\": \"R\", \"log2 fold change IC90\": -0.040613716714220115, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08501661434245472, \"functional effect\": -2.6684, \"times_seen\": 11.0}, {\"site\": 886, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0752598841458665, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08299926953459819, \"functional effect\": -0.7051, \"times_seen\": 12.0}, {\"site\": 886, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03977196991460998, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08506623213539512, \"functional effect\": -3.131, \"times_seen\": 4.0}, {\"site\": 886, \"mutant\": \"W\", \"log2 fold change IC90\": -0.003243870691070824, \"epitope\": \"all\", \"reference_site\": \"889\", \"IC90\": 0.08724755202346288, \"functional effect\": -2.4742, \"times_seen\": 3.0}, {\"site\": 887, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": null, \"functional effect\": -3.0009, \"times_seen\": null}, {\"site\": 887, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 887, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0027474172538391266, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.08727758040734442, \"functional effect\": -1.2195, \"times_seen\": 8.0}, {\"site\": 887, \"mutant\": \"E\", \"log2 fold change IC90\": 0.00020651286864602252, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.08745646505217793, \"functional effect\": -3.2528, \"times_seen\": 1.0}, {\"site\": 887, \"mutant\": \"L\", \"log2 fold change IC90\": 1.1471088215078558, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.19366177872009463, \"functional effect\": 0.1666, \"times_seen\": 25.0}, {\"site\": 887, \"mutant\": \"S\", \"log2 fold change IC90\": 0.020357224955241372, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.08868657602618794, \"functional effect\": -1.1744, \"times_seen\": 31.0}, {\"site\": 887, \"mutant\": \"T\", \"log2 fold change IC90\": 0.3432995916179435, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.11093618515685001, \"functional effect\": -0.4164, \"times_seen\": 81.0}, {\"site\": 887, \"mutant\": \"V\", \"log2 fold change IC90\": -0.2539895310524795, \"epitope\": \"all\", \"reference_site\": \"890\", \"IC90\": 0.07332824406292614, \"functional effect\": 0.4444, \"times_seen\": 109.0}, {\"site\": 888, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -2.7005, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"D\", \"log2 fold change IC90\": 0.019877812886693602, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08865711009603094, \"functional effect\": -2.7908, \"times_seen\": 4.0}, {\"site\": 888, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0029254330280883297, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08726681179228779, \"functional effect\": -2.9939, \"times_seen\": 3.0}, {\"site\": 888, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -2.6779, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00564367309404268, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08710254366401929, \"functional effect\": -2.7203, \"times_seen\": 1.0}, {\"site\": 888, \"mutant\": \"R\", \"log2 fold change IC90\": -0.015613847550530226, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": 0.08650267073994822, \"functional effect\": -2.1703, \"times_seen\": 9.0}, {\"site\": 888, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -2.8072, \"times_seen\": null}, {\"site\": 888, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"891\", \"IC90\": null, \"functional effect\": -1.7267, \"times_seen\": null}, {\"site\": 889, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 889, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0031960948118110394, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08725044133645862, \"functional effect\": -1.5322, \"times_seen\": 3.0}, {\"site\": 889, \"mutant\": \"E\", \"log2 fold change IC90\": 0.03601721034282609, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08965448361839067, \"functional effect\": -2.5049, \"times_seen\": 2.0}, {\"site\": 889, \"mutant\": \"G\", \"log2 fold change IC90\": -0.005514384278395352, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08711034981085365, \"functional effect\": -1.2289, \"times_seen\": 1.0}, {\"site\": 889, \"mutant\": \"P\", \"log2 fold change IC90\": 0.06500108848464907, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.09147386514861984, \"functional effect\": -2.3039, \"times_seen\": 2.0}, {\"site\": 889, \"mutant\": \"S\", \"log2 fold change IC90\": -0.056094044968390995, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.08410925044735879, \"functional effect\": -0.3493, \"times_seen\": 27.0}, {\"site\": 889, \"mutant\": \"T\", \"log2 fold change IC90\": 0.10537909609732797, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.09407019010068904, \"functional effect\": -0.5448, \"times_seen\": 28.0}, {\"site\": 889, \"mutant\": \"V\", \"log2 fold change IC90\": 0.3251790720007202, \"epitope\": \"all\", \"reference_site\": \"892\", \"IC90\": 0.10955151994753615, \"functional effect\": -0.6734, \"times_seen\": 93.0}, {\"site\": 890, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 890, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": null, \"functional effect\": -3.0043, \"times_seen\": null}, {\"site\": 890, \"mutant\": \"E\", \"log2 fold change IC90\": -5.187523817027454, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.002399548214354296, \"functional effect\": -2.9218, \"times_seen\": 1.0}, {\"site\": 890, \"mutant\": \"L\", \"log2 fold change IC90\": -0.13896009139624854, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.07941427896479439, \"functional effect\": -0.0444, \"times_seen\": 3.0}, {\"site\": 890, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": null, \"functional effect\": -0.3442, \"times_seen\": null}, {\"site\": 890, \"mutant\": \"S\", \"log2 fold change IC90\": -0.10814945871859764, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.08112851409153515, \"functional effect\": -2.1832, \"times_seen\": 9.0}, {\"site\": 890, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05047364281736719, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.08443755948987113, \"functional effect\": -2.3667, \"times_seen\": 7.0}, {\"site\": 890, \"mutant\": \"V\", \"log2 fold change IC90\": -0.041839711907819814, \"epitope\": \"all\", \"reference_site\": \"893\", \"IC90\": 0.0849443983279167, \"functional effect\": -2.3519, \"times_seen\": 15.0}, {\"site\": 891, \"mutant\": \"F\", \"log2 fold change IC90\": -0.028440856356825472, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08573698396923106, \"functional effect\": -0.4678, \"times_seen\": 11.0}, {\"site\": 891, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": null, \"functional effect\": -2.0987, \"times_seen\": null}, {\"site\": 891, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0016020182156955699, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08754110179601311, \"functional effect\": -2.6892, \"times_seen\": 9.0}, {\"site\": 891, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 891, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02408701245620032, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08891615332851303, \"functional effect\": -2.8638, \"times_seen\": 3.0}, {\"site\": 891, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005549427293771244, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08710823392900217, \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 891, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0072639023627310215, \"epitope\": \"all\", \"reference_site\": \"894\", \"IC90\": 0.08700477742102601, \"functional effect\": -2.0644, \"times_seen\": 2.0}, {\"site\": 892, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": null, \"functional effect\": -2.98, \"times_seen\": null}, {\"site\": 892, \"mutant\": \"E\", \"log2 fold change IC90\": -0.005720886784812568, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08709788202125474, \"functional effect\": -1.3112, \"times_seen\": 1.0}, {\"site\": 892, \"mutant\": \"H\", \"log2 fold change IC90\": -0.037988107472025606, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.0851714798188517, \"functional effect\": -0.7551, \"times_seen\": 18.0}, {\"site\": 892, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004783089314059103, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.0871545168084099, \"functional effect\": -2.1146, \"times_seen\": 14.0}, {\"site\": 892, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005238738272508036, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08712699498764528, \"functional effect\": -2.9371, \"times_seen\": 1.0}, {\"site\": 892, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 892, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005576612263178109, \"epitope\": \"all\", \"reference_site\": \"895\", \"IC90\": 0.08710659254790859, \"functional effect\": -2.7823, \"times_seen\": 1.0}, {\"site\": 893, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": null, \"functional effect\": -2.1962, \"times_seen\": null}, {\"site\": 893, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 893, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009555376421981421, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.086866694917983, \"functional effect\": -1.1891, \"times_seen\": 2.0}, {\"site\": 893, \"mutant\": \"M\", \"log2 fold change IC90\": -0.006064305138490189, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.08707715175554588, \"functional effect\": -1.5844, \"times_seen\": 9.0}, {\"site\": 893, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": null, \"functional effect\": -3.0026, \"times_seen\": null}, {\"site\": 893, \"mutant\": \"R\", \"log2 fold change IC90\": 0.014884297121020231, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.08835077689087159, \"functional effect\": -2.6707, \"times_seen\": 3.0}, {\"site\": 893, \"mutant\": \"T\", \"log2 fold change IC90\": 0.025816921563309645, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.08902283500094382, \"functional effect\": -2.4205, \"times_seen\": 12.0}, {\"site\": 893, \"mutant\": \"V\", \"log2 fold change IC90\": 0.012993930238792185, \"epitope\": \"all\", \"reference_site\": \"896\", \"IC90\": 0.088235086460556, \"functional effect\": -1.8276, \"times_seen\": 4.0}, {\"site\": 894, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": null, \"functional effect\": -3.1269, \"times_seen\": null}, {\"site\": 894, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010329136695180555, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08682011821641007, \"functional effect\": -2.9962, \"times_seen\": 1.0}, {\"site\": 894, \"mutant\": \"M\", \"log2 fold change IC90\": -1.4871588687324107, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.0311925101458378, \"functional effect\": -2.696, \"times_seen\": 3.0}, {\"site\": 894, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 894, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.019604563184400955, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08626372172984133, \"functional effect\": -2.8016, \"times_seen\": 2.0}, {\"site\": 894, \"mutant\": \"S\", \"log2 fold change IC90\": 0.012585370457505678, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08821010252240725, \"functional effect\": -2.7618, \"times_seen\": 2.0}, {\"site\": 894, \"mutant\": \"T\", \"log2 fold change IC90\": 0.004201364725186797, \"epitope\": \"all\", \"reference_site\": \"897\", \"IC90\": 0.08769896937411693, \"functional effect\": -3.0526, \"times_seen\": 3.0}, {\"site\": 895, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -2.8593, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -2.4705, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0041591847710302065, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": 0.08719221559908744, \"functional effect\": -2.7561, \"times_seen\": 2.0}, {\"site\": 895, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00399965538371475, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": 0.08720185761588052, \"functional effect\": -0.7948, \"times_seen\": 1.0}, {\"site\": 895, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -3.2656, \"times_seen\": null}, {\"site\": 895, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"898\", \"IC90\": null, \"functional effect\": -1.7283, \"times_seen\": null}, {\"site\": 896, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 896, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004706829152747881, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08715912387573094, \"functional effect\": -2.8743, \"times_seen\": 1.0}, {\"site\": 896, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02952064121209259, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08925167006516012, \"functional effect\": -1.9038, \"times_seen\": 6.0}, {\"site\": 896, \"mutant\": \"S\", \"log2 fold change IC90\": 0.07687243691628312, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.09222967158233217, \"functional effect\": -1.4036, \"times_seen\": 14.0}, {\"site\": 896, \"mutant\": \"T\", \"log2 fold change IC90\": -0.12716337188746923, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08006630074704733, \"functional effect\": -1.3045, \"times_seen\": 32.0}, {\"site\": 896, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004632418357376146, \"epitope\": \"all\", \"reference_site\": \"899\", \"IC90\": 0.08716361945297074, \"functional effect\": -0.7626, \"times_seen\": 18.0}, {\"site\": 897, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -0.2541, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"I\", \"log2 fold change IC90\": 0.36364569018871706, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.11251178462178116, \"functional effect\": -1.8462, \"times_seen\": 31.0}, {\"site\": 897, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -3.114, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"L\", \"log2 fold change IC90\": 0.2699611316584821, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.10543775520529684, \"functional effect\": -1.6964, \"times_seen\": 5.0}, {\"site\": 897, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -1.9072, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.01877368142765564, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": 0.08858928449700541, \"functional effect\": -2.7554, \"times_seen\": 7.0}, {\"site\": 897, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -2.5266, \"times_seen\": null}, {\"site\": 897, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"900\", \"IC90\": null, \"functional effect\": -2.9127, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"*\", \"log2 fold change IC90\": 0.029691525459494193, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08926224236723244, \"functional effect\": -2.6303, \"times_seen\": 1.0}, {\"site\": 898, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": null, \"functional effect\": -2.0623, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"H\", \"log2 fold change IC90\": -0.030110582478095713, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08563781230307435, \"functional effect\": -2.9477, \"times_seen\": 4.0}, {\"site\": 898, \"mutant\": \"K\", \"log2 fold change IC90\": 0.09234169621068541, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.0932239226782258, \"functional effect\": -2.5577, \"times_seen\": 7.0}, {\"site\": 898, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 898, \"mutant\": \"R\", \"log2 fold change IC90\": 0.02944503950446302, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.0892469931225766, \"functional effect\": -2.8476, \"times_seen\": 1.0}, {\"site\": 898, \"mutant\": \"T\", \"log2 fold change IC90\": -0.008275859851392033, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08694377058188575, \"functional effect\": -2.9964, \"times_seen\": 1.0}, {\"site\": 898, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0023461744034588795, \"epitope\": \"all\", \"reference_site\": \"901\", \"IC90\": 0.08730185745440862, \"functional effect\": -2.6917, \"times_seen\": 3.0}, {\"site\": 899, \"mutant\": \"I\", \"log2 fold change IC90\": -0.007862316817078698, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.08696869625457113, \"functional effect\": -2.8048, \"times_seen\": 2.0}, {\"site\": 899, \"mutant\": \"L\", \"log2 fold change IC90\": 0.007380866736096039, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.08789245900908829, \"functional effect\": -1.6681, \"times_seen\": 7.0}, {\"site\": 899, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 899, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": null, \"functional effect\": -3.0013, \"times_seen\": null}, {\"site\": 899, \"mutant\": \"V\", \"log2 fold change IC90\": 0.011816422729950822, \"epitope\": \"all\", \"reference_site\": \"902\", \"IC90\": 0.08816309959874072, \"functional effect\": -2.7013, \"times_seen\": 1.0}, {\"site\": 900, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0025287535543728826, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.08759735311217612, \"functional effect\": -2.7687, \"times_seen\": 1.0}, {\"site\": 900, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -2.9945, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -2.4536, \"times_seen\": null}, {\"site\": 900, \"mutant\": \"S\", \"log2 fold change IC90\": 0.021484657001190087, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.08875590957511151, \"functional effect\": -2.7799, \"times_seen\": 5.0}, {\"site\": 900, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003386446354769937, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": 0.08723893012996695, \"functional effect\": -2.598, \"times_seen\": 4.0}, {\"site\": 900, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"903\", \"IC90\": null, \"functional effect\": -0.2027, \"times_seen\": null}, {\"site\": 901, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": null, \"functional effect\": -2.9972, \"times_seen\": null}, {\"site\": 901, \"mutant\": \"C\", \"log2 fold change IC90\": 0.018074631218596815, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.08854636942834015, \"functional effect\": -1.5884, \"times_seen\": 3.0}, {\"site\": 901, \"mutant\": \"F\", \"log2 fold change IC90\": -0.021099114975011442, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.08617440358615602, \"functional effect\": 0.1966, \"times_seen\": 18.0}, {\"site\": 901, \"mutant\": \"H\", \"log2 fold change IC90\": 1.3327342526068848, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.22025345977776228, \"functional effect\": -0.7952, \"times_seen\": 21.0}, {\"site\": 901, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": null, \"functional effect\": -2.0755, \"times_seen\": null}, {\"site\": 901, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"904\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": null, \"functional effect\": -2.8707, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"G\", \"log2 fold change IC90\": 1.3333270643818529, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 0.22034398180088943, \"functional effect\": -2.9103, \"times_seen\": 7.0}, {\"site\": 902, \"mutant\": \"K\", \"log2 fold change IC90\": 3.987869035701921, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 1.3873880560118936, \"functional effect\": -2.5305, \"times_seen\": 5.0}, {\"site\": 902, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": null, \"functional effect\": -2.9329, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 902, \"mutant\": \"S\", \"log2 fold change IC90\": 0.15146626510756306, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": 0.09712379462759668, \"functional effect\": -2.7124, \"times_seen\": 1.0}, {\"site\": 902, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"905\", \"IC90\": null, \"functional effect\": -2.0613, \"times_seen\": null}, {\"site\": 903, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 903, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": null, \"functional effect\": -3.0814, \"times_seen\": null}, {\"site\": 903, \"mutant\": \"L\", \"log2 fold change IC90\": -0.050481931441468286, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.08443707437752213, \"functional effect\": -2.4218, \"times_seen\": 2.0}, {\"site\": 903, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02568723604466436, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.08901483299544627, \"functional effect\": -1.3472, \"times_seen\": 1.0}, {\"site\": 903, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007468868734161405, \"epitope\": \"all\", \"reference_site\": \"906\", \"IC90\": 0.08699241736828296, \"functional effect\": -2.4569, \"times_seen\": 1.0}, {\"site\": 904, \"mutant\": \"D\", \"log2 fold change IC90\": 0.007685694469407484, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08791103181134267, \"functional effect\": -1.1061, \"times_seen\": 7.0}, {\"site\": 904, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": null, \"functional effect\": -0.115, \"times_seen\": null}, {\"site\": 904, \"mutant\": \"H\", \"log2 fold change IC90\": -0.010663841771281131, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08679997829573799, \"functional effect\": -1.3226, \"times_seen\": 6.0}, {\"site\": 904, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005145438386072873, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08713262972081101, \"functional effect\": -2.0818, \"times_seen\": 1.0}, {\"site\": 904, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0050176283371964935, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08714034924479688, \"functional effect\": -2.0047, \"times_seen\": 1.0}, {\"site\": 904, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 904, \"mutant\": \"S\", \"log2 fold change IC90\": -0.014294087307452519, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08658183855839234, \"functional effect\": 0.378, \"times_seen\": 8.0}, {\"site\": 904, \"mutant\": \"T\", \"log2 fold change IC90\": -0.029701420282225187, \"epitope\": \"all\", \"reference_site\": \"907\", \"IC90\": 0.08566210345512928, \"functional effect\": 0.4444, \"times_seen\": 7.0}, {\"site\": 905, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": null, \"functional effect\": -2.5548, \"times_seen\": null}, {\"site\": 905, \"mutant\": \"C\", \"log2 fold change IC90\": -0.022702790413594902, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08607866679427803, \"functional effect\": -1.4382, \"times_seen\": 8.0}, {\"site\": 905, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01870387426011107, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08631759384765753, \"functional effect\": -2.1475, \"times_seen\": 8.0}, {\"site\": 905, \"mutant\": \"E\", \"log2 fold change IC90\": 0.028029515518830223, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08915946991074096, \"functional effect\": -1.2561, \"times_seen\": 1.0}, {\"site\": 905, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 905, \"mutant\": \"S\", \"log2 fold change IC90\": 0.030932174496488597, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.0893390366601689, \"functional effect\": 0.2966, \"times_seen\": 6.0}, {\"site\": 905, \"mutant\": \"V\", \"log2 fold change IC90\": 0.01665134049103058, \"epitope\": \"all\", \"reference_site\": \"908\", \"IC90\": 0.08845905708764595, \"functional effect\": -2.625, \"times_seen\": 2.0}, {\"site\": 906, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 906, \"mutant\": \"L\", \"log2 fold change IC90\": 0.021827760522106367, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.08877702012559009, \"functional effect\": -2.6475, \"times_seen\": 1.0}, {\"site\": 906, \"mutant\": \"M\", \"log2 fold change IC90\": -0.012220125234357861, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.08670639473675604, \"functional effect\": -2.758, \"times_seen\": 1.0}, {\"site\": 906, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": null, \"functional effect\": -2.9022, \"times_seen\": null}, {\"site\": 906, \"mutant\": \"V\", \"log2 fold change IC90\": -0.22266382267488988, \"epitope\": \"all\", \"reference_site\": \"909\", \"IC90\": 0.0749378559380341, \"functional effect\": -0.2602, \"times_seen\": 39.0}, {\"site\": 907, \"mutant\": \"*\", \"log2 fold change IC90\": -0.004666150519884935, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08716158147341162, \"functional effect\": -1.9937, \"times_seen\": 1.0}, {\"site\": 907, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": null, \"functional effect\": -2.9794, \"times_seen\": null}, {\"site\": 907, \"mutant\": \"E\", \"log2 fold change IC90\": -0.015582950485632007, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08650452331944389, \"functional effect\": -1.4367, \"times_seen\": 20.0}, {\"site\": 907, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 907, \"mutant\": \"R\", \"log2 fold change IC90\": 0.039504371933704686, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08987145103747678, \"functional effect\": -1.4034, \"times_seen\": 2.0}, {\"site\": 907, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004705082465486255, \"epitope\": \"all\", \"reference_site\": \"910\", \"IC90\": 0.08715922940033541, \"functional effect\": -1.2281, \"times_seen\": 1.0}, {\"site\": 908, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": null, \"functional effect\": -2.9987, \"times_seen\": null}, {\"site\": 908, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": null, \"functional effect\": -1.1709, \"times_seen\": null}, {\"site\": 908, \"mutant\": \"I\", \"log2 fold change IC90\": 2.6440647281367937, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.5466036739880308, \"functional effect\": -0.9528, \"times_seen\": 13.0}, {\"site\": 908, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02492412648448293, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.08896776129552592, \"functional effect\": -1.7645, \"times_seen\": 10.0}, {\"site\": 908, \"mutant\": \"M\", \"log2 fold change IC90\": 0.10271431141948814, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.09389659455516881, \"functional effect\": -2.6745, \"times_seen\": 1.0}, {\"site\": 908, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"911\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 909, \"mutant\": \"A\", \"log2 fold change IC90\": 0.049405022935720425, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.09049032472080082, \"functional effect\": -1.8363, \"times_seen\": 18.0}, {\"site\": 909, \"mutant\": \"I\", \"log2 fold change IC90\": -0.014839352248594869, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.08654912123463293, \"functional effect\": -2.7658, \"times_seen\": 5.0}, {\"site\": 909, \"mutant\": \"L\", \"log2 fold change IC90\": -1.7468171435628406, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.02605465912725297, \"functional effect\": -1.7886, \"times_seen\": 3.0}, {\"site\": 909, \"mutant\": \"N\", \"log2 fold change IC90\": -0.03349797967572598, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.08543697360614885, \"functional effect\": -2.2041, \"times_seen\": 4.0}, {\"site\": 909, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"912\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": null, \"functional effect\": -2.375, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"E\", \"log2 fold change IC90\": 0.08463168735928889, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.09272704698059563, \"functional effect\": -0.0022, \"times_seen\": 13.0}, {\"site\": 910, \"mutant\": \"H\", \"log2 fold change IC90\": -0.011962960102689829, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.08672185181412759, \"functional effect\": -2.2618, \"times_seen\": 3.0}, {\"site\": 910, \"mutant\": \"K\", \"log2 fold change IC90\": 0.044037584938177644, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.09015428778598611, \"functional effect\": -2.4255, \"times_seen\": 3.0}, {\"site\": 910, \"mutant\": \"L\", \"log2 fold change IC90\": -0.004764756253566225, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.08715562433227025, \"functional effect\": -2.311, \"times_seen\": 10.0}, {\"site\": 910, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": null, \"functional effect\": -3.1312, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 910, \"mutant\": \"R\", \"log2 fold change IC90\": -0.021304713929088753, \"epitope\": \"all\", \"reference_site\": \"913\", \"IC90\": 0.08616212371802767, \"functional effect\": -2.3632, \"times_seen\": 3.0}, {\"site\": 911, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": -1.9481, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"D\", \"log2 fold change IC90\": 0.026996657410440817, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.08909566146726404, \"functional effect\": -2.6387, \"times_seen\": 2.0}, {\"site\": 911, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": null, \"functional effect\": -1.2052, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 911, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01157377648466448, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.08674524918905922, \"functional effect\": -1.9719, \"times_seen\": 5.0}, {\"site\": 911, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.009172784640605901, \"epitope\": \"all\", \"reference_site\": \"914\", \"IC90\": 0.08688973436136145, \"functional effect\": -2.6153, \"times_seen\": 2.0}, {\"site\": 912, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -3.1761, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -1.4918, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -2.9571, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"I\", \"log2 fold change IC90\": -0.003699388340434733, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.0872200087623208, \"functional effect\": -0.4727, \"times_seen\": 26.0}, {\"site\": 912, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0009060756083744145, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.08738904571358516, \"functional effect\": -2.1996, \"times_seen\": 1.0}, {\"site\": 912, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": null, \"functional effect\": -2.8687, \"times_seen\": null}, {\"site\": 912, \"mutant\": \"S\", \"log2 fold change IC90\": -0.016823036451421042, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.08643019925816137, \"functional effect\": -2.468, \"times_seen\": 2.0}, {\"site\": 912, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"915\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03814596389433695, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": 0.08516216105835164, \"functional effect\": -1.7646, \"times_seen\": 29.0}, {\"site\": 913, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -2.3525, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -2.9718, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 913, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"916\", \"IC90\": null, \"functional effect\": -3.0003, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -1.2773, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -2.9051, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"F\", \"log2 fold change IC90\": -0.060227630511038535, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": 0.08386860694747712, \"functional effect\": -0.1498, \"times_seen\": 7.0}, {\"site\": 914, \"mutant\": \"H\", \"log2 fold change IC90\": -0.029731762185818147, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": 0.08566030187968941, \"functional effect\": -2.4585, \"times_seen\": 3.0}, {\"site\": 914, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -3.2613, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": null, \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 914, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"917\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 915, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0007835561379258341, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08739646745826997, \"functional effect\": -2.393, \"times_seen\": 2.0}, {\"site\": 915, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 915, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05311891005936672, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09072357137536116, \"functional effect\": -0.5814, \"times_seen\": 4.0}, {\"site\": 915, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0008335926733176177, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08739343636681955, \"functional effect\": -2.073, \"times_seen\": 7.0}, {\"site\": 915, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 915, \"mutant\": \"G\", \"log2 fold change IC90\": 0.05666184104723564, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09094664163120739, \"functional effect\": -1.6992, \"times_seen\": 10.0}, {\"site\": 915, \"mutant\": \"K\", \"log2 fold change IC90\": 0.13494785231561596, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09601809918070683, \"functional effect\": -1.4865, \"times_seen\": 29.0}, {\"site\": 915, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0709961832536349, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.09185477412577821, \"functional effect\": 0.4295, \"times_seen\": 5.0}, {\"site\": 915, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0006835527969677984, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08748538809064348, \"functional effect\": -1.0897, \"times_seen\": 1.0}, {\"site\": 915, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01343724785194999, \"epitope\": \"all\", \"reference_site\": \"918\", \"IC90\": 0.08663327615816548, \"functional effect\": -2.3041, \"times_seen\": 6.0}, {\"site\": 916, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": null, \"functional effect\": -2.0581, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": null, \"functional effect\": -2.9814, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 916, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00179358620773711, \"epitope\": \"all\", \"reference_site\": \"919\", \"IC90\": 0.08733530264874716, \"functional effect\": -2.0356, \"times_seen\": 1.0}, {\"site\": 917, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": null, \"functional effect\": -2.9981, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": null, \"functional effect\": -1.4999, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"K\", \"log2 fold change IC90\": -0.027051861303683304, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.08581956940094213, \"functional effect\": -2.9199, \"times_seen\": 4.0}, {\"site\": 917, \"mutant\": \"L\", \"log2 fold change IC90\": -1.3743371486374212, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.03372974414827823, \"functional effect\": -1.2457, \"times_seen\": 23.0}, {\"site\": 917, \"mutant\": \"P\", \"log2 fold change IC90\": -0.01386954522021923, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.08660732075822251, \"functional effect\": -3.1032, \"times_seen\": 1.0}, {\"site\": 917, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 917, \"mutant\": \"R\", \"log2 fold change IC90\": -0.014304598498783712, \"epitope\": \"all\", \"reference_site\": \"920\", \"IC90\": 0.08658120774250279, \"functional effect\": -2.7045, \"times_seen\": 1.0}, {\"site\": 918, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": null, \"functional effect\": -2.1339, \"times_seen\": null}, {\"site\": 918, \"mutant\": \"E\", \"log2 fold change IC90\": -0.04600653601455562, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.08469941397043886, \"functional effect\": 0.1925, \"times_seen\": 9.0}, {\"site\": 918, \"mutant\": \"I\", \"log2 fold change IC90\": 0.035792305603984345, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.08964050828330435, \"functional effect\": 0.25, \"times_seen\": 11.0}, {\"site\": 918, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 918, \"mutant\": \"N\", \"log2 fold change IC90\": 0.052847834983498425, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.09070652647813693, \"functional effect\": -0.1995, \"times_seen\": 11.0}, {\"site\": 918, \"mutant\": \"R\", \"log2 fold change IC90\": -0.06988269791808323, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": 0.08330920009922725, \"functional effect\": 0.2591, \"times_seen\": 8.0}, {\"site\": 918, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"921\", \"IC90\": null, \"functional effect\": -2.9992, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03776386164821541, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.08518471950745514, \"functional effect\": -0.1284, \"times_seen\": 18.0}, {\"site\": 919, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03914850794693221, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.08510300152899548, \"functional effect\": -1.1435, \"times_seen\": 5.0}, {\"site\": 919, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03270124119811091, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.08548416980641088, \"functional effect\": 0.2593, \"times_seen\": 20.0}, {\"site\": 919, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": null, \"functional effect\": -2.9695, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 919, \"mutant\": \"S\", \"log2 fold change IC90\": -1.2433192249312819, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.03693629855390066, \"functional effect\": 0.3547, \"times_seen\": 13.0}, {\"site\": 919, \"mutant\": \"V\", \"log2 fold change IC90\": 0.28268135611590767, \"epitope\": \"all\", \"reference_site\": \"922\", \"IC90\": 0.10637150899678705, \"functional effect\": -0.7893, \"times_seen\": 14.0}, {\"site\": 920, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": null, \"functional effect\": -3.0157, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010135320130632668, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": 0.0868317827102429, \"functional effect\": -2.1225, \"times_seen\": 3.0}, {\"site\": 920, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": null, \"functional effect\": -1.6968, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": null, \"functional effect\": -3.0143, \"times_seen\": null}, {\"site\": 920, \"mutant\": \"V\", \"log2 fold change IC90\": 0.005009911979792649, \"epitope\": \"all\", \"reference_site\": \"923\", \"IC90\": 0.08774813335732491, \"functional effect\": 0.3428, \"times_seen\": 8.0}, {\"site\": 921, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 921, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04339555478903394, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08485284127899038, \"functional effect\": -1.8836, \"times_seen\": 5.0}, {\"site\": 921, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03226770210574258, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08550986220666887, \"functional effect\": -1.6701, \"times_seen\": 1.0}, {\"site\": 921, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": null, \"functional effect\": -3.001, \"times_seen\": null}, {\"site\": 921, \"mutant\": \"P\", \"log2 fold change IC90\": -0.029588654414336227, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.08566879935322069, \"functional effect\": -3.1013, \"times_seen\": 1.0}, {\"site\": 921, \"mutant\": \"S\", \"log2 fold change IC90\": -0.027044715285451847, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.0858199944871239, \"functional effect\": -0.5601, \"times_seen\": 19.0}, {\"site\": 921, \"mutant\": \"T\", \"log2 fold change IC90\": -0.7423724665533135, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.05227010499136702, \"functional effect\": -2.3407, \"times_seen\": 18.0}, {\"site\": 921, \"mutant\": \"V\", \"log2 fold change IC90\": -4.312633184958702, \"epitope\": \"all\", \"reference_site\": \"924\", \"IC90\": 0.00440045722602669, \"functional effect\": -2.117, \"times_seen\": 23.0}, {\"site\": 922, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 922, \"mutant\": \"A\", \"log2 fold change IC90\": 8.976564308485595e-05, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.0874493880981094, \"functional effect\": -0.5035, \"times_seen\": 7.0}, {\"site\": 922, \"mutant\": \"D\", \"log2 fold change IC90\": -0.010414066852191048, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08681500734472401, \"functional effect\": -0.1584, \"times_seen\": 20.0}, {\"site\": 922, \"mutant\": \"I\", \"log2 fold change IC90\": 0.11481413678416195, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.09468741316890845, \"functional effect\": -1.4171, \"times_seen\": 10.0}, {\"site\": 922, \"mutant\": \"K\", \"log2 fold change IC90\": -0.022613568397077115, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08608399040703205, \"functional effect\": -0.7135, \"times_seen\": 14.0}, {\"site\": 922, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 922, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010289875280091905, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08806986161538426, \"functional effect\": -0.7559, \"times_seen\": 5.0}, {\"site\": 922, \"mutant\": \"S\", \"log2 fold change IC90\": 0.034925909484119874, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.08958669173108824, \"functional effect\": -0.5794, \"times_seen\": 11.0}, {\"site\": 922, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0535426270389817, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.0907502206409025, \"functional effect\": -0.8221, \"times_seen\": 10.0}, {\"site\": 922, \"mutant\": \"Y\", \"log2 fold change IC90\": -1.2527291216589898, \"epitope\": \"all\", \"reference_site\": \"925\", \"IC90\": 0.036696167609243005, \"functional effect\": -0.2915, \"times_seen\": 20.0}, {\"site\": 923, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": null, \"functional effect\": -2.7711, \"times_seen\": null}, {\"site\": 923, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 923, \"mutant\": \"H\", \"log2 fold change IC90\": -0.02714912884964727, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08581378357837728, \"functional effect\": -1.3777, \"times_seen\": 6.0}, {\"site\": 923, \"mutant\": \"K\", \"log2 fold change IC90\": -0.005667753858070032, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08710108980285278, \"functional effect\": -1.2896, \"times_seen\": 15.0}, {\"site\": 923, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07530853840380185, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08299647046780978, \"functional effect\": -0.1869, \"times_seen\": 16.0}, {\"site\": 923, \"mutant\": \"N\", \"log2 fold change IC90\": 0.011276319609596097, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08813010007235816, \"functional effect\": -2.9703, \"times_seen\": 3.0}, {\"site\": 923, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0054668209036675295, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.0871132217487147, \"functional effect\": -2.9053, \"times_seen\": 1.0}, {\"site\": 923, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 923, \"mutant\": \"R\", \"log2 fold change IC90\": 0.013938064873475625, \"epitope\": \"all\", \"reference_site\": \"926\", \"IC90\": 0.08829284854011939, \"functional effect\": -2.3285, \"times_seen\": 8.0}, {\"site\": 924, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008717607500439067, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.08691715281049509, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 924, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 924, \"mutant\": \"I\", \"log2 fold change IC90\": -0.014507166908023825, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.0865690517526457, \"functional effect\": -2.2115, \"times_seen\": 4.0}, {\"site\": 924, \"mutant\": \"L\", \"log2 fold change IC90\": -0.024817414883971958, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.0859525897546652, \"functional effect\": -2.0167, \"times_seen\": 5.0}, {\"site\": 924, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": null, \"functional effect\": -1.6718, \"times_seen\": null}, {\"site\": 924, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": null, \"functional effect\": -1.4792, \"times_seen\": null}, {\"site\": 924, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.009142953108188127, \"epitope\": \"all\", \"reference_site\": \"927\", \"IC90\": 0.08799987514266124, \"functional effect\": -2.7049, \"times_seen\": 1.0}, {\"site\": 925, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008137030648311148, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.0869521375026956, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 925, \"mutant\": \"D\", \"log2 fold change IC90\": 0.028079927395800154, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08916258545119136, \"functional effect\": -2.5455, \"times_seen\": 2.0}, {\"site\": 925, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 925, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004702497556121951, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08715938556563974, \"functional effect\": -2.717, \"times_seen\": 1.0}, {\"site\": 925, \"mutant\": \"K\", \"log2 fold change IC90\": -0.006687802995822229, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.08703952725018638, \"functional effect\": -2.2128, \"times_seen\": 3.0}, {\"site\": 925, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 925, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": null, \"functional effect\": -2.9878, \"times_seen\": null}, {\"site\": 925, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"928\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 926, \"mutant\": \"-\", \"log2 fold change IC90\": -0.00954921737230259, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08686706576380718, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 926, \"mutant\": \"A\", \"log2 fold change IC90\": -0.006063017127449828, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08707722949642646, \"functional effect\": 0.2868, \"times_seen\": 1.0}, {\"site\": 926, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": null, \"functional effect\": -2.9792, \"times_seen\": null}, {\"site\": 926, \"mutant\": \"F\", \"log2 fold change IC90\": 0.33224090825573455, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.11008907736343256, \"functional effect\": -0.488, \"times_seen\": 3.0}, {\"site\": 926, \"mutant\": \"G\", \"log2 fold change IC90\": 0.025899537866498862, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08902793306249407, \"functional effect\": 0.2219, \"times_seen\": 4.0}, {\"site\": 926, \"mutant\": \"I\", \"log2 fold change IC90\": 0.4299106320699916, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.11780012425190613, \"functional effect\": -0.0993, \"times_seen\": 28.0}, {\"site\": 926, \"mutant\": \"N\", \"log2 fold change IC90\": -1.192338987404307, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.03826484448454456, \"functional effect\": -0.1288, \"times_seen\": 20.0}, {\"site\": 926, \"mutant\": \"P\", \"log2 fold change IC90\": 0.024603637514592498, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08894799965598878, \"functional effect\": -2.9645, \"times_seen\": 1.0}, {\"site\": 926, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01841052485157105, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08633514696102837, \"functional effect\": -0.2751, \"times_seen\": 7.0}, {\"site\": 926, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 926, \"mutant\": \"T\", \"log2 fold change IC90\": -0.014878911182030736, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.0865467480761422, \"functional effect\": 0.1001, \"times_seen\": 30.0}, {\"site\": 926, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1252171780038226, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08017438297594565, \"functional effect\": -0.4408, \"times_seen\": 14.0}, {\"site\": 926, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02771294198652601, \"epitope\": \"all\", \"reference_site\": \"929\", \"IC90\": 0.08913990761173676, \"functional effect\": -0.4279, \"times_seen\": 8.0}, {\"site\": 927, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008834471488643783, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08691011246347378, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 927, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 927, \"mutant\": \"C\", \"log2 fold change IC90\": -0.010804486721291147, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08679151678223856, \"functional effect\": -0.7905, \"times_seen\": 4.0}, {\"site\": 927, \"mutant\": \"D\", \"log2 fold change IC90\": -0.003764703595243556, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08721606013285897, \"functional effect\": -2.3045, \"times_seen\": 1.0}, {\"site\": 927, \"mutant\": \"H\", \"log2 fold change IC90\": -0.013378746817682157, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.0866367891937489, \"functional effect\": -0.575, \"times_seen\": 11.0}, {\"site\": 927, \"mutant\": \"L\", \"log2 fold change IC90\": -0.011000164334613694, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08677974575323394, \"functional effect\": -1.8084, \"times_seen\": 3.0}, {\"site\": 927, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": null, \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 927, \"mutant\": \"R\", \"log2 fold change IC90\": -0.035971198323780845, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08529063408611677, \"functional effect\": -0.4934, \"times_seen\": 7.0}, {\"site\": 927, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0025617929929071708, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08728881069384593, \"functional effect\": -2.9182, \"times_seen\": 1.0}, {\"site\": 927, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03607766653676456, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08528434002806891, \"functional effect\": -1.9236, \"times_seen\": 4.0}, {\"site\": 927, \"mutant\": \"V\", \"log2 fold change IC90\": -0.013707905279455897, \"epitope\": \"all\", \"reference_site\": \"930\", \"IC90\": 0.08661702480936757, \"functional effect\": -2.7247, \"times_seen\": 3.0}, {\"site\": 928, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0088450946400197, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08690947251126249, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 928, \"mutant\": \"F\", \"log2 fold change IC90\": -0.01485620183301047, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08654811041240992, \"functional effect\": -0.4695, \"times_seen\": 2.0}, {\"site\": 928, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 928, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0007315843388596807, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08748830078384202, \"functional effect\": 0.4444, \"times_seen\": 2.0}, {\"site\": 928, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02233030013930201, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.0861008943648282, \"functional effect\": -0.3694, \"times_seen\": 5.0}, {\"site\": 928, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": null, \"functional effect\": -3.0956, \"times_seen\": null}, {\"site\": 928, \"mutant\": \"T\", \"log2 fold change IC90\": -0.005479037800957432, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08711248406767579, \"functional effect\": -2.4165, \"times_seen\": 1.0}, {\"site\": 928, \"mutant\": \"V\", \"log2 fold change IC90\": -0.031443986345861895, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": 0.08555869853786972, \"functional effect\": -0.6782, \"times_seen\": 8.0}, {\"site\": 928, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"931\", \"IC90\": null, \"functional effect\": -2.9437, \"times_seen\": null}, {\"site\": 929, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008597495799082895, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08692438940686446, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 929, \"mutant\": \"A\", \"log2 fold change IC90\": -0.004445825324306633, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08717489361381785, \"functional effect\": -0.1662, \"times_seen\": 7.0}, {\"site\": 929, \"mutant\": \"C\", \"log2 fold change IC90\": 0.011258863483580026, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08812903373416334, \"functional effect\": -0.0122, \"times_seen\": 14.0}, {\"site\": 929, \"mutant\": \"D\", \"log2 fold change IC90\": 0.02475093774520077, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08895708177617213, \"functional effect\": 0.3633, \"times_seen\": 79.0}, {\"site\": 929, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 929, \"mutant\": \"L\", \"log2 fold change IC90\": -0.003185882003574753, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.0872510589827072, \"functional effect\": 0.1018, \"times_seen\": 8.0}, {\"site\": 929, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00475220733427112, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08715638243680486, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 929, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004532239519076025, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08716967218973486, \"functional effect\": 0.0408, \"times_seen\": 26.0}, {\"site\": 929, \"mutant\": \"S\", \"log2 fold change IC90\": 0.08577622793491324, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.09280063978720135, \"functional effect\": -0.1759, \"times_seen\": 41.0}, {\"site\": 929, \"mutant\": \"T\", \"log2 fold change IC90\": -0.41660280830097074, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.06551184208481227, \"functional effect\": 0.2646, \"times_seen\": 18.0}, {\"site\": 929, \"mutant\": \"V\", \"log2 fold change IC90\": -0.00019316704743267013, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.08743223973067112, \"functional effect\": 0.1853, \"times_seen\": 27.0}, {\"site\": 929, \"mutant\": \"W\", \"log2 fold change IC90\": 0.10392911068859834, \"epitope\": \"all\", \"reference_site\": \"932\", \"IC90\": 0.09397569204164052, \"functional effect\": 0.2353, \"times_seen\": 15.0}, {\"site\": 930, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008268577650950737, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08694420944356095, \"functional effect\": -0.472, \"times_seen\": 1.0}, {\"site\": 930, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0736662619069688, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.09202493244934903, \"functional effect\": 0.2416, \"times_seen\": 21.0}, {\"site\": 930, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": null, \"functional effect\": -2.0862, \"times_seen\": null}, {\"site\": 930, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004286665786739745, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08718451136443461, \"functional effect\": 0.2802, \"times_seen\": 2.0}, {\"site\": 930, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0006243105891155192, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08748179570210177, \"functional effect\": -0.2066, \"times_seen\": 4.0}, {\"site\": 930, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 930, \"mutant\": \"N\", \"log2 fold change IC90\": -0.008142368539111159, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08695181578525497, \"functional effect\": 0.3491, \"times_seen\": 11.0}, {\"site\": 930, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": null, \"functional effect\": -3.3409, \"times_seen\": null}, {\"site\": 930, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.057615664319101104, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08402058666789741, \"functional effect\": 0.0968, \"times_seen\": 16.0}, {\"site\": 930, \"mutant\": \"R\", \"log2 fold change IC90\": -0.027859110330043374, \"epitope\": \"all\", \"reference_site\": \"933\", \"IC90\": 0.08577156314627953, \"functional effect\": 0.2991, \"times_seen\": 11.0}, {\"site\": 931, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 931, \"mutant\": \"F\", \"log2 fold change IC90\": 0.006116796300193522, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08781548251934686, \"functional effect\": -0.1736, \"times_seen\": 6.0}, {\"site\": 931, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 931, \"mutant\": \"L\", \"log2 fold change IC90\": 0.026595487914578362, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.0890708901250207, \"functional effect\": 0.1345, \"times_seen\": 9.0}, {\"site\": 931, \"mutant\": \"M\", \"log2 fold change IC90\": 0.008309015893204201, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08794902228559284, \"functional effect\": -0.5846, \"times_seen\": 24.0}, {\"site\": 931, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": null, \"functional effect\": -2.5924, \"times_seen\": null}, {\"site\": 931, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004873965571409612, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08714902706412718, \"functional effect\": -1.3962, \"times_seen\": 8.0}, {\"site\": 931, \"mutant\": \"T\", \"log2 fold change IC90\": -0.022963555898337887, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08606310957935522, \"functional effect\": 0.0468, \"times_seen\": 8.0}, {\"site\": 931, \"mutant\": \"V\", \"log2 fold change IC90\": -0.021218327779134995, \"epitope\": \"all\", \"reference_site\": \"934\", \"IC90\": 0.08616728311538947, \"functional effect\": 0.1355, \"times_seen\": 22.0}, {\"site\": 932, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": null, \"functional effect\": -2.4683, \"times_seen\": null}, {\"site\": 932, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 932, \"mutant\": \"E\", \"log2 fold change IC90\": 0.012873396598891003, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08822771494296387, \"functional effect\": -0.131, \"times_seen\": 8.0}, {\"site\": 932, \"mutant\": \"H\", \"log2 fold change IC90\": -0.03764304845969953, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08519185328708712, \"functional effect\": 0.3085, \"times_seen\": 33.0}, {\"site\": 932, \"mutant\": \"K\", \"log2 fold change IC90\": 1.145001215117505, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.19337906837782717, \"functional effect\": 0.1257, \"times_seen\": 32.0}, {\"site\": 932, \"mutant\": \"L\", \"log2 fold change IC90\": -0.034393979640022186, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08538392860598404, \"functional effect\": -0.6738, \"times_seen\": 12.0}, {\"site\": 932, \"mutant\": \"P\", \"log2 fold change IC90\": 0.026841890093353367, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08908610410655934, \"functional effect\": -0.1322, \"times_seen\": 2.0}, {\"site\": 932, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 932, \"mutant\": \"R\", \"log2 fold change IC90\": -0.07308633457588722, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08312440962757499, \"functional effect\": -0.061, \"times_seen\": 66.0}, {\"site\": 932, \"mutant\": \"S\", \"log2 fold change IC90\": -0.012016117287825168, \"epitope\": \"all\", \"reference_site\": \"935\", \"IC90\": 0.08671865654106216, \"functional effect\": 0.1988, \"times_seen\": 9.0}, {\"site\": 933, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0006820041411278953, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.0874026195541094, \"functional effect\": -2.8982, \"times_seen\": 2.0}, {\"site\": 933, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 933, \"mutant\": \"A\", \"log2 fold change IC90\": -0.24238321014491856, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.0739205409052533, \"functional effect\": -0.1452, \"times_seen\": 116.0}, {\"site\": 933, \"mutant\": \"C\", \"log2 fold change IC90\": -2.9489309966282393, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.011324344370867833, \"functional effect\": -0.341, \"times_seen\": 33.0}, {\"site\": 933, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 933, \"mutant\": \"E\", \"log2 fold change IC90\": 0.09289967282325454, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.09325998492798011, \"functional effect\": 0.0714, \"times_seen\": 117.0}, {\"site\": 933, \"mutant\": \"F\", \"log2 fold change IC90\": -0.032116844140316625, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.0855188041645614, \"functional effect\": -0.3468, \"times_seen\": 31.0}, {\"site\": 933, \"mutant\": \"G\", \"log2 fold change IC90\": -0.037343398912452315, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08520954957826028, \"functional effect\": -0.6219, \"times_seen\": 142.0}, {\"site\": 933, \"mutant\": \"H\", \"log2 fold change IC90\": -0.10369602497335718, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.0813793354174824, \"functional effect\": 0.01, \"times_seen\": 58.0}, {\"site\": 933, \"mutant\": \"I\", \"log2 fold change IC90\": 0.007418136217650549, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08789472958505784, \"functional effect\": 0.0112, \"times_seen\": 26.0}, {\"site\": 933, \"mutant\": \"K\", \"log2 fold change IC90\": -0.6070164636652138, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.05741159194122377, \"functional effect\": -0.1797, \"times_seen\": 42.0}, {\"site\": 933, \"mutant\": \"L\", \"log2 fold change IC90\": -0.2193136334619564, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.07511207690166644, \"functional effect\": 0.0491, \"times_seen\": 98.0}, {\"site\": 933, \"mutant\": \"M\", \"log2 fold change IC90\": 0.93272461157499, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.1669197934372279, \"functional effect\": 0.1434, \"times_seen\": 45.0}, {\"site\": 933, \"mutant\": \"N\", \"log2 fold change IC90\": -0.08006989888840353, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08272300676555054, \"functional effect\": -0.1217, \"times_seen\": 91.0}, {\"site\": 933, \"mutant\": \"P\", \"log2 fold change IC90\": -0.008803489475306969, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08691197888645286, \"functional effect\": -1.156, \"times_seen\": 43.0}, {\"site\": 933, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.11679733688655597, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.09481766468429075, \"functional effect\": -0.0172, \"times_seen\": 49.0}, {\"site\": 933, \"mutant\": \"R\", \"log2 fold change IC90\": -0.5457807578019309, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.059900903591078754, \"functional effect\": 0.0486, \"times_seen\": 120.0}, {\"site\": 933, \"mutant\": \"S\", \"log2 fold change IC90\": -0.6109447193995756, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.057255480879880485, \"functional effect\": -0.1925, \"times_seen\": 109.0}, {\"site\": 933, \"mutant\": \"T\", \"log2 fold change IC90\": -3.288242280959697, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.008950971889794313, \"functional effect\": 0.0011, \"times_seen\": 93.0}, {\"site\": 933, \"mutant\": \"V\", \"log2 fold change IC90\": 0.302220985821171, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.10782198796891333, \"functional effect\": -0.0316, \"times_seen\": 120.0}, {\"site\": 933, \"mutant\": \"W\", \"log2 fold change IC90\": -0.09979123243750088, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.08159989474391416, \"functional effect\": -0.2886, \"times_seen\": 56.0}, {\"site\": 933, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.07146548184750084, \"epitope\": \"all\", \"reference_site\": \"936\", \"IC90\": 0.09188465870091675, \"functional effect\": -0.1037, \"times_seen\": 108.0}, {\"site\": 934, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"A\", \"log2 fold change IC90\": -0.017601083335845952, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08638359993156235, \"functional effect\": -0.3931, \"times_seen\": 11.0}, {\"site\": 934, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": -0.3044, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0035629477193555004, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.0872282578479384, \"functional effect\": -0.2537, \"times_seen\": 3.0}, {\"site\": 934, \"mutant\": \"H\", \"log2 fold change IC90\": -0.019647487991021437, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.086261155145509, \"functional effect\": 0.1902, \"times_seen\": 13.0}, {\"site\": 934, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01039730515161077, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08681601599559692, \"functional effect\": -0.0403, \"times_seen\": 3.0}, {\"site\": 934, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": 0.6679, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": null, \"functional effect\": -1.7045, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 934, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003383084803077035, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08723913340127974, \"functional effect\": 0.3646, \"times_seen\": 19.0}, {\"site\": 934, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.018417290844303272, \"epitope\": \"all\", \"reference_site\": \"937\", \"IC90\": 0.08633474206492035, \"functional effect\": 0.085, \"times_seen\": 4.0}, {\"site\": 935, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"F\", \"log2 fold change IC90\": 0.009222976331746473, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08800475644382953, \"functional effect\": -0.2643, \"times_seen\": 16.0}, {\"site\": 935, \"mutant\": \"I\", \"log2 fold change IC90\": -0.028609328302110836, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08572697254427686, \"functional effect\": -0.4609, \"times_seen\": 19.0}, {\"site\": 935, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"M\", \"log2 fold change IC90\": -0.5332478892058624, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.060423536883304145, \"functional effect\": -0.4381, \"times_seen\": 7.0}, {\"site\": 935, \"mutant\": \"P\", \"log2 fold change IC90\": -0.10126596155936408, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08151652559535383, \"functional effect\": -2.0938, \"times_seen\": 1.0}, {\"site\": 935, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": null, \"functional effect\": -3.2628, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": null, \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 935, \"mutant\": \"T\", \"log2 fold change IC90\": -0.008121352508203311, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08695308243919515, \"functional effect\": -2.6479, \"times_seen\": 1.0}, {\"site\": 935, \"mutant\": \"V\", \"log2 fold change IC90\": -0.006178697565061215, \"epitope\": \"all\", \"reference_site\": \"938\", \"IC90\": 0.08707024761329135, \"functional effect\": -1.144, \"times_seen\": 6.0}, {\"site\": 936, \"mutant\": \"*\", \"log2 fold change IC90\": 3.4183247849222362, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.9348631644359522, \"functional effect\": -2.8311, \"times_seen\": 10.0}, {\"site\": 936, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": null, \"functional effect\": -1.3564, \"times_seen\": null}, {\"site\": 936, \"mutant\": \"A\", \"log2 fold change IC90\": -0.09736242085325829, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08173738581937633, \"functional effect\": 0.1087, \"times_seen\": 165.0}, {\"site\": 936, \"mutant\": \"C\", \"log2 fold change IC90\": 0.07673502808004, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09222088762732163, \"functional effect\": -0.6542, \"times_seen\": 61.0}, {\"site\": 936, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0665303373505041, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0915708783538568, \"functional effect\": -0.4094, \"times_seen\": 72.0}, {\"site\": 936, \"mutant\": \"E\", \"log2 fold change IC90\": -0.087855492493216, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08227778931187738, \"functional effect\": 0.0374, \"times_seen\": 62.0}, {\"site\": 936, \"mutant\": \"F\", \"log2 fold change IC90\": -0.029330674533551915, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08568411984864664, \"functional effect\": -1.7198, \"times_seen\": 99.0}, {\"site\": 936, \"mutant\": \"G\", \"log2 fold change IC90\": -0.250319285021703, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.07351503012591484, \"functional effect\": -0.0382, \"times_seen\": 62.0}, {\"site\": 936, \"mutant\": \"H\", \"log2 fold change IC90\": -0.058049311350861554, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08399533545287878, \"functional effect\": -0.4664, \"times_seen\": 49.0}, {\"site\": 936, \"mutant\": \"I\", \"log2 fold change IC90\": -1.3229128130849241, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.034953712875540194, \"functional effect\": -0.3065, \"times_seen\": 47.0}, {\"site\": 936, \"mutant\": \"K\", \"log2 fold change IC90\": 0.021336337858632877, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0887467853157433, \"functional effect\": -0.2325, \"times_seen\": 27.0}, {\"site\": 936, \"mutant\": \"L\", \"log2 fold change IC90\": 0.25150834783418163, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.10409774209991146, \"functional effect\": -0.6924, \"times_seen\": 140.0}, {\"site\": 936, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0452572868506998, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08474341318375665, \"functional effect\": -0.2322, \"times_seen\": 26.0}, {\"site\": 936, \"mutant\": \"N\", \"log2 fold change IC90\": 0.12072950493488563, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09507644948804389, \"functional effect\": 0.309, \"times_seen\": 69.0}, {\"site\": 936, \"mutant\": \"P\", \"log2 fold change IC90\": -0.015798597929582457, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08649159398601462, \"functional effect\": -1.9366, \"times_seen\": 51.0}, {\"site\": 936, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.010215621192559275, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0880653288633203, \"functional effect\": 0.0502, \"times_seen\": 36.0}, {\"site\": 936, \"mutant\": \"R\", \"log2 fold change IC90\": -0.31746794258242667, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.07017176163234923, \"functional effect\": -0.2679, \"times_seen\": 76.0}, {\"site\": 936, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 936, \"mutant\": \"T\", \"log2 fold change IC90\": -0.07687181664243362, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.08290658570190103, \"functional effect\": -0.5069, \"times_seen\": 140.0}, {\"site\": 936, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04284650567567699, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09007988773241413, \"functional effect\": -0.5598, \"times_seen\": 83.0}, {\"site\": 936, \"mutant\": \"W\", \"log2 fold change IC90\": 0.04881516983049228, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.09045333485982421, \"functional effect\": -1.3738, \"times_seen\": 21.0}, {\"site\": 936, \"mutant\": \"Y\", \"log2 fold change IC90\": -1.9971033031167278, \"epitope\": \"all\", \"reference_site\": \"939\", \"IC90\": 0.02190492417305374, \"functional effect\": -0.7689, \"times_seen\": 137.0}, {\"site\": 937, \"mutant\": \"A\", \"log2 fold change IC90\": 0.036655347599397696, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08969414863388099, \"functional effect\": -0.3529, \"times_seen\": 33.0}, {\"site\": 937, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": null, \"functional effect\": -1.6109, \"times_seen\": null}, {\"site\": 937, \"mutant\": \"F\", \"log2 fold change IC90\": 0.034157354515140376, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08953897966524416, \"functional effect\": -0.5469, \"times_seen\": 40.0}, {\"site\": 937, \"mutant\": \"G\", \"log2 fold change IC90\": -0.011948219604099091, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08672273788486934, \"functional effect\": -0.1498, \"times_seen\": 9.0}, {\"site\": 937, \"mutant\": \"I\", \"log2 fold change IC90\": 0.016645024823449504, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08845866984241364, \"functional effect\": -0.7398, \"times_seen\": 4.0}, {\"site\": 937, \"mutant\": \"N\", \"log2 fold change IC90\": -0.13783732288501493, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.0794761066926557, \"functional effect\": -0.0335, \"times_seen\": 57.0}, {\"site\": 937, \"mutant\": \"P\", \"log2 fold change IC90\": -0.04469724331572857, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08477631633538756, \"functional effect\": 0.0747, \"times_seen\": 21.0}, {\"site\": 937, \"mutant\": \"R\", \"log2 fold change IC90\": -0.021896780827138182, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08612677094176281, \"functional effect\": -0.1382, \"times_seen\": 7.0}, {\"site\": 937, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 937, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011805972745365148, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08673128899572063, \"functional effect\": 0.0508, \"times_seen\": 32.0}, {\"site\": 937, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.01242069482620139, \"epitope\": \"all\", \"reference_site\": \"940\", \"IC90\": 0.08669434128339022, \"functional effect\": -0.64, \"times_seen\": 20.0}, {\"site\": 938, \"mutant\": \"A\", \"log2 fold change IC90\": -0.05300137777663691, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08428974661569037, \"functional effect\": -0.4902, \"times_seen\": 24.0}, {\"site\": 938, \"mutant\": \"C\", \"log2 fold change IC90\": -0.003532429195095567, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08723010307910965, \"functional effect\": -0.3262, \"times_seen\": 14.0}, {\"site\": 938, \"mutant\": \"F\", \"log2 fold change IC90\": 1.5118641715752905, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.24937115560172954, \"functional effect\": -1.7567, \"times_seen\": 19.0}, {\"site\": 938, \"mutant\": \"I\", \"log2 fold change IC90\": -0.010873860309553281, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08678734341640766, \"functional effect\": -2.3738, \"times_seen\": 20.0}, {\"site\": 938, \"mutant\": \"K\", \"log2 fold change IC90\": -0.1375668537562733, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.07949100786567864, \"functional effect\": 0.0207, \"times_seen\": 41.0}, {\"site\": 938, \"mutant\": \"P\", \"log2 fold change IC90\": -0.053882875107055014, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08423826068841292, \"functional effect\": 0.1825, \"times_seen\": 21.0}, {\"site\": 938, \"mutant\": \"S\", \"log2 fold change IC90\": -0.09512463002705385, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.08186426856228027, \"functional effect\": 0.2632, \"times_seen\": 63.0}, {\"site\": 938, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"941\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 939, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 939, \"mutant\": \"D\", \"log2 fold change IC90\": -1.2172865498373366, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.03760884430154616, \"functional effect\": 0.3651, \"times_seen\": 2.0}, {\"site\": 939, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": null, \"functional effect\": -0.4675, \"times_seen\": null}, {\"site\": 939, \"mutant\": \"K\", \"log2 fold change IC90\": 0.011004177520178163, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08811347726092525, \"functional effect\": 0.3737, \"times_seen\": 9.0}, {\"site\": 939, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06727883640469015, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08345969725325506, \"functional effect\": -0.0503, \"times_seen\": 23.0}, {\"site\": 939, \"mutant\": \"T\", \"log2 fold change IC90\": -0.09632679414795073, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08179608139043655, \"functional effect\": 0.1371, \"times_seen\": 73.0}, {\"site\": 939, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04533394396081595, \"epitope\": \"all\", \"reference_site\": \"942\", \"IC90\": 0.08473891049095693, \"functional effect\": 0.0072, \"times_seen\": 28.0}, {\"site\": 940, \"mutant\": \"*\", \"log2 fold change IC90\": -0.03440633502133384, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08538319737280683, \"functional effect\": -2.1849, \"times_seen\": 4.0}, {\"site\": 940, \"mutant\": \"A\", \"log2 fold change IC90\": -0.8279367280363813, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.04926017645269196, \"functional effect\": -0.1717, \"times_seen\": 54.0}, {\"site\": 940, \"mutant\": \"C\", \"log2 fold change IC90\": -0.18675545309642516, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.07682644890937347, \"functional effect\": 0.0675, \"times_seen\": 45.0}, {\"site\": 940, \"mutant\": \"D\", \"log2 fold change IC90\": -0.5319083630174835, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.060479665513972825, \"functional effect\": 0.3598, \"times_seen\": 41.0}, {\"site\": 940, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0383941876003703, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08514750969533127, \"functional effect\": 0.0001, \"times_seen\": 11.0}, {\"site\": 940, \"mutant\": \"F\", \"log2 fold change IC90\": -0.12385726724350041, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08024999244711555, \"functional effect\": 0.2112, \"times_seen\": 46.0}, {\"site\": 940, \"mutant\": \"G\", \"log2 fold change IC90\": 0.4161528786209332, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.11668210410630288, \"functional effect\": 0.1457, \"times_seen\": 72.0}, {\"site\": 940, \"mutant\": \"H\", \"log2 fold change IC90\": -0.011139057081961234, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08677139159883182, \"functional effect\": 0.0644, \"times_seen\": 24.0}, {\"site\": 940, \"mutant\": \"I\", \"log2 fold change IC90\": 0.032402685617324116, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08943014463480893, \"functional effect\": -0.2432, \"times_seen\": 31.0}, {\"site\": 940, \"mutant\": \"K\", \"log2 fold change IC90\": 0.10658690419439179, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.09414897758350096, \"functional effect\": 0.2043, \"times_seen\": 20.0}, {\"site\": 940, \"mutant\": \"L\", \"log2 fold change IC90\": -0.09410986154256462, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08192187082779243, \"functional effect\": -0.1505, \"times_seen\": 68.0}, {\"site\": 940, \"mutant\": \"M\", \"log2 fold change IC90\": -0.017113958104789054, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08641277223393103, \"functional effect\": 0.1411, \"times_seen\": 28.0}, {\"site\": 940, \"mutant\": \"N\", \"log2 fold change IC90\": 0.047575333903825956, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.09037563367155695, \"functional effect\": 0.3343, \"times_seen\": 42.0}, {\"site\": 940, \"mutant\": \"P\", \"log2 fold change IC90\": -0.11186592793094777, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08091979111575008, \"functional effect\": 0.4107, \"times_seen\": 73.0}, {\"site\": 940, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004413811262930884, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08717682808595542, \"functional effect\": 0.1028, \"times_seen\": 3.0}, {\"site\": 940, \"mutant\": \"R\", \"log2 fold change IC90\": -0.06367053927354084, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08366869796981881, \"functional effect\": -0.2136, \"times_seen\": 59.0}, {\"site\": 940, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 940, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07903665501702296, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.0923681311388437, \"functional effect\": 0.1314, \"times_seen\": 36.0}, {\"site\": 940, \"mutant\": \"V\", \"log2 fold change IC90\": -0.23459723378753325, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.07432055575234472, \"functional effect\": -0.2812, \"times_seen\": 64.0}, {\"site\": 940, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0066859270265903275, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.08785013180230399, \"functional effect\": 0.363, \"times_seen\": 7.0}, {\"site\": 940, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.12080944755312609, \"epitope\": \"all\", \"reference_site\": \"943\", \"IC90\": 0.09508171801027307, \"functional effect\": 0.2419, \"times_seen\": 46.0}, {\"site\": 941, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 941, \"mutant\": \"C\", \"log2 fold change IC90\": -0.012556433171454624, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08668618488684171, \"functional effect\": -0.1909, \"times_seen\": 6.0}, {\"site\": 941, \"mutant\": \"D\", \"log2 fold change IC90\": 0.012146338135757577, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08818326303588046, \"functional effect\": -1.4308, \"times_seen\": 5.0}, {\"site\": 941, \"mutant\": \"P\", \"log2 fold change IC90\": -0.008314097000791143, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08694146625713572, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 941, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": null, \"functional effect\": -0.1028, \"times_seen\": null}, {\"site\": 941, \"mutant\": \"S\", \"log2 fold change IC90\": 0.022282109204273606, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08880498312060911, \"functional effect\": 0.3315, \"times_seen\": 20.0}, {\"site\": 941, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06810537168477937, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08341189600233619, \"functional effect\": 0.25, \"times_seen\": 24.0}, {\"site\": 941, \"mutant\": \"V\", \"log2 fold change IC90\": -0.14919496295002915, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.07885288613181558, \"functional effect\": 0.1042, \"times_seen\": 23.0}, {\"site\": 941, \"mutant\": \"W\", \"log2 fold change IC90\": 0.03233797648414715, \"epitope\": \"all\", \"reference_site\": \"944\", \"IC90\": 0.08942613351867121, \"functional effect\": -0.2985, \"times_seen\": 1.0}, {\"site\": 942, \"mutant\": \"C\", \"log2 fold change IC90\": 0.01643436297447507, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08844575407992997, \"functional effect\": -0.2514, \"times_seen\": 9.0}, {\"site\": 942, \"mutant\": \"F\", \"log2 fold change IC90\": 0.028863264354708085, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08921101101002692, \"functional effect\": -1.0993, \"times_seen\": 8.0}, {\"site\": 942, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0020284491743970483, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08756698096830857, \"functional effect\": -0.5101, \"times_seen\": 4.0}, {\"site\": 942, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 942, \"mutant\": \"M\", \"log2 fold change IC90\": 0.03844407217811166, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08980542483872982, \"functional effect\": -0.0568, \"times_seen\": 4.0}, {\"site\": 942, \"mutant\": \"P\", \"log2 fold change IC90\": 0.027917208434857562, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08915252953175683, \"functional effect\": -2.7921, \"times_seen\": 17.0}, {\"site\": 942, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0044782006780809056, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08717293735398915, \"functional effect\": -1.8188, \"times_seen\": 1.0}, {\"site\": 942, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00018555500365297593, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08743270104770175, \"functional effect\": -2.9466, \"times_seen\": 1.0}, {\"site\": 942, \"mutant\": \"S\", \"log2 fold change IC90\": -0.013686019342859802, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08661833881478, \"functional effect\": -1.3313, \"times_seen\": 11.0}, {\"site\": 942, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0022057942497062644, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08731035269706007, \"functional effect\": -0.1611, \"times_seen\": 6.0}, {\"site\": 942, \"mutant\": \"V\", \"log2 fold change IC90\": -0.001227052971002808, \"epitope\": \"all\", \"reference_site\": \"945\", \"IC90\": 0.08736960516342251, \"functional effect\": -0.1081, \"times_seen\": 1.0}, {\"site\": 943, \"mutant\": \"A\", \"log2 fold change IC90\": 0.004316464798132845, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08770596639022867, \"functional effect\": -0.3291, \"times_seen\": 14.0}, {\"site\": 943, \"mutant\": \"C\", \"log2 fold change IC90\": 0.8527667070162886, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.15792035475716582, \"functional effect\": 0.1577, \"times_seen\": 4.0}, {\"site\": 943, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01934386491492771, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08627931118869932, \"functional effect\": 0.2621, \"times_seen\": 77.0}, {\"site\": 943, \"mutant\": \"E\", \"log2 fold change IC90\": -0.009800251966251108, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08685195186873354, \"functional effect\": 0.3216, \"times_seen\": 10.0}, {\"site\": 943, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 943, \"mutant\": \"R\", \"log2 fold change IC90\": 0.023968746811543006, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08890886468129955, \"functional effect\": -0.0948, \"times_seen\": 21.0}, {\"site\": 943, \"mutant\": \"S\", \"log2 fold change IC90\": 0.5601129613461797, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.1289260138044389, \"functional effect\": 0.2133, \"times_seen\": 5.0}, {\"site\": 943, \"mutant\": \"T\", \"log2 fold change IC90\": 0.017072598664150132, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08848489036543733, \"functional effect\": -0.4021, \"times_seen\": 2.0}, {\"site\": 943, \"mutant\": \"V\", \"log2 fold change IC90\": -0.011722317308711627, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.08673631830129747, \"functional effect\": -0.25, \"times_seen\": 21.0}, {\"site\": 943, \"mutant\": \"W\", \"log2 fold change IC90\": 0.09104254103195271, \"epitope\": \"all\", \"reference_site\": \"946\", \"IC90\": 0.09314001178667704, \"functional effect\": -0.7046, \"times_seen\": 7.0}, {\"site\": 944, \"mutant\": \"E\", \"log2 fold change IC90\": -0.020509234469857883, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08620964526423686, \"functional effect\": -0.3957, \"times_seen\": 12.0}, {\"site\": 944, \"mutant\": \"G\", \"log2 fold change IC90\": 0.004047721367992032, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08768963015395743, \"functional effect\": -1.64, \"times_seen\": 1.0}, {\"site\": 944, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02104235337753546, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08872870282511662, \"functional effect\": 0.4763, \"times_seen\": 2.0}, {\"site\": 944, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 944, \"mutant\": \"N\", \"log2 fold change IC90\": 0.021428192827227164, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.08875243591580918, \"functional effect\": -0.2645, \"times_seen\": 10.0}, {\"site\": 944, \"mutant\": \"R\", \"log2 fold change IC90\": 0.952641333677082, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": 0.16924013744766878, \"functional effect\": 0.3292, \"times_seen\": 4.0}, {\"site\": 944, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"947\", \"IC90\": null, \"functional effect\": 0.1167, \"times_seen\": null}, {\"site\": 945, \"mutant\": \"F\", \"log2 fold change IC90\": -0.018551195556708443, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.086326729219522, \"functional effect\": -2.9634, \"times_seen\": 5.0}, {\"site\": 945, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004146326463319319, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.08719299272058756, \"functional effect\": -2.0743, \"times_seen\": 1.0}, {\"site\": 945, \"mutant\": \"I\", \"log2 fold change IC90\": 0.07771211277023331, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.09228336662326447, \"functional effect\": -0.1733, \"times_seen\": 27.0}, {\"site\": 945, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 945, \"mutant\": \"M\", \"log2 fold change IC90\": -0.009171629530105295, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.08688980393066188, \"functional effect\": -2.5633, \"times_seen\": 2.0}, {\"site\": 945, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004386684296979855, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": 0.0871784672855183, \"functional effect\": -3.126, \"times_seen\": 1.0}, {\"site\": 945, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"948\", \"IC90\": null, \"functional effect\": -3.2637, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": null, \"functional effect\": -2.5809, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0028234010731734756, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.08727298379539382, \"functional effect\": 0.096, \"times_seen\": 4.0}, {\"site\": 946, \"mutant\": \"H\", \"log2 fold change IC90\": -0.034206306241472875, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.08539503652132047, \"functional effect\": -0.6883, \"times_seen\": 15.0}, {\"site\": 946, \"mutant\": \"K\", \"log2 fold change IC90\": -0.011194856385965377, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.0867680355953179, \"functional effect\": -1.4144, \"times_seen\": 2.0}, {\"site\": 946, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": null, \"functional effect\": -1.3087, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 946, \"mutant\": \"R\", \"log2 fold change IC90\": -0.31076297516935814, \"epitope\": \"all\", \"reference_site\": \"949\", \"IC90\": 0.07049864596149215, \"functional effect\": -1.6677, \"times_seen\": 18.0}, {\"site\": 947, \"mutant\": \"*\", \"log2 fold change IC90\": -0.007772125074479783, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08697413337276552, \"functional effect\": -2.9788, \"times_seen\": 3.0}, {\"site\": 947, \"mutant\": \"A\", \"log2 fold change IC90\": -0.13988845690260207, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.07936319279664895, \"functional effect\": -0.3039, \"times_seen\": 49.0}, {\"site\": 947, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006151253458344989, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08707190394940387, \"functional effect\": -1.4446, \"times_seen\": 10.0}, {\"site\": 947, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 947, \"mutant\": \"E\", \"log2 fold change IC90\": -0.2446277224925322, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.07380562641177693, \"functional effect\": -0.2797, \"times_seen\": 66.0}, {\"site\": 947, \"mutant\": \"F\", \"log2 fold change IC90\": -0.07642521559829216, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.0829322542584549, \"functional effect\": -1.3733, \"times_seen\": 19.0}, {\"site\": 947, \"mutant\": \"G\", \"log2 fold change IC90\": 0.11217025624419524, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.09451404807533627, \"functional effect\": -0.6903, \"times_seen\": 71.0}, {\"site\": 947, \"mutant\": \"H\", \"log2 fold change IC90\": -2.4922838859831478, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.015540949364663513, \"functional effect\": -0.6543, \"times_seen\": 18.0}, {\"site\": 947, \"mutant\": \"I\", \"log2 fold change IC90\": -0.014609588481261138, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.0865629061546515, \"functional effect\": -1.0843, \"times_seen\": 26.0}, {\"site\": 947, \"mutant\": \"K\", \"log2 fold change IC90\": -1.418822202080861, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.032705569169200754, \"functional effect\": -0.4556, \"times_seen\": 23.0}, {\"site\": 947, \"mutant\": \"L\", \"log2 fold change IC90\": 0.33259385928324864, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.11011601362180201, \"functional effect\": -0.9281, \"times_seen\": 29.0}, {\"site\": 947, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05205231457228965, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08434521406578954, \"functional effect\": -0.2803, \"times_seen\": 12.0}, {\"site\": 947, \"mutant\": \"N\", \"log2 fold change IC90\": -0.027535021583758968, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08579083313754986, \"functional effect\": -0.1851, \"times_seen\": 47.0}, {\"site\": 947, \"mutant\": \"P\", \"log2 fold change IC90\": 0.020945913315292018, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08872277176180698, \"functional effect\": -2.5739, \"times_seen\": 3.0}, {\"site\": 947, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.10573195765363576, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.09409320107141964, \"functional effect\": -0.3614, \"times_seen\": 24.0}, {\"site\": 947, \"mutant\": \"R\", \"log2 fold change IC90\": -2.249575042317547, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.018388241022114244, \"functional effect\": -0.5694, \"times_seen\": 43.0}, {\"site\": 947, \"mutant\": \"S\", \"log2 fold change IC90\": 0.7573721806111751, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.14781601744926512, \"functional effect\": -0.507, \"times_seen\": 63.0}, {\"site\": 947, \"mutant\": \"T\", \"log2 fold change IC90\": -0.012154897612882435, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08671031502454359, \"functional effect\": -0.3584, \"times_seen\": 23.0}, {\"site\": 947, \"mutant\": \"V\", \"log2 fold change IC90\": 0.006164838883498373, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08781840687464108, \"functional effect\": -0.9083, \"times_seen\": 32.0}, {\"site\": 947, \"mutant\": \"W\", \"log2 fold change IC90\": -0.07682778072822441, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.08290911632889483, \"functional effect\": -1.3042, \"times_seen\": 22.0}, {\"site\": 947, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.007766908035726316, \"epitope\": \"all\", \"reference_site\": \"950\", \"IC90\": 0.0879159807223511, \"functional effect\": -1.1047, \"times_seen\": 20.0}, {\"site\": 948, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": null, \"functional effect\": -2.7742, \"times_seen\": null}, {\"site\": 948, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004861218541650498, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.08714979707866087, \"functional effect\": -1.763, \"times_seen\": 1.0}, {\"site\": 948, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0039411868569039, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.0872053917428598, \"functional effect\": -1.4484, \"times_seen\": 3.0}, {\"site\": 948, \"mutant\": \"M\", \"log2 fold change IC90\": 0.006647040849182101, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.08784776393544723, \"functional effect\": -1.2045, \"times_seen\": 17.0}, {\"site\": 948, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"951\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 949, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 949, \"mutant\": \"A\", \"log2 fold change IC90\": 0.007850860227973228, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.0879210968098521, \"functional effect\": -1.0805, \"times_seen\": 6.0}, {\"site\": 949, \"mutant\": \"C\", \"log2 fold change IC90\": 0.016230379110088313, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.088433249544458, \"functional effect\": -2.3314, \"times_seen\": 3.0}, {\"site\": 949, \"mutant\": \"F\", \"log2 fold change IC90\": -0.013502451450464631, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.086629360795911, \"functional effect\": -1.4429, \"times_seen\": 18.0}, {\"site\": 949, \"mutant\": \"H\", \"log2 fold change IC90\": -0.016487633766220172, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08645029518285431, \"functional effect\": -1.7319, \"times_seen\": 3.0}, {\"site\": 949, \"mutant\": \"I\", \"log2 fold change IC90\": -0.21807886074798558, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.07517639128660426, \"functional effect\": -0.0287, \"times_seen\": 24.0}, {\"site\": 949, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01625378188874229, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08646430937285432, \"functional effect\": -1.4796, \"times_seen\": 5.0}, {\"site\": 949, \"mutant\": \"M\", \"log2 fold change IC90\": -0.027710179012837576, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.08578041791522305, \"functional effect\": -1.1134, \"times_seen\": 8.0}, {\"site\": 949, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"952\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"D\", \"log2 fold change IC90\": -0.008997078217186842, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.08690031734234754, \"functional effect\": 0.4444, \"times_seen\": 4.0}, {\"site\": 950, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": null, \"functional effect\": -0.1214, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0041142512505682426, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.08719493129028008, \"functional effect\": -0.9502, \"times_seen\": 6.0}, {\"site\": 950, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0479660092588472, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.09040011030228033, \"functional effect\": -0.8839, \"times_seen\": 3.0}, {\"site\": 950, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 950, \"mutant\": \"S\", \"log2 fold change IC90\": -0.036593958233663015, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.08525382511146119, \"functional effect\": -0.5432, \"times_seen\": 24.0}, {\"site\": 950, \"mutant\": \"T\", \"log2 fold change IC90\": 0.7484538974656629, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": 0.14690508416513118, \"functional effect\": -0.1638, \"times_seen\": 18.0}, {\"site\": 950, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"953\", \"IC90\": null, \"functional effect\": -0.5388, \"times_seen\": null}, {\"site\": 951, \"mutant\": \"*\", \"log2 fold change IC90\": -0.03722110300442591, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08521677301816627, \"functional effect\": -2.3194, \"times_seen\": 8.0}, {\"site\": 951, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004903142857218044, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08714726456665822, \"functional effect\": -0.8217, \"times_seen\": 1.0}, {\"site\": 951, \"mutant\": \"A\", \"log2 fold change IC90\": -0.44798885771421665, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.06410201314988995, \"functional effect\": 0.354, \"times_seen\": 80.0}, {\"site\": 951, \"mutant\": \"C\", \"log2 fold change IC90\": -0.6092794595764507, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.057321607329009705, \"functional effect\": -0.3075, \"times_seen\": 63.0}, {\"site\": 951, \"mutant\": \"D\", \"log2 fold change IC90\": -0.056251038249143084, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08410009822297095, \"functional effect\": 0.054, \"times_seen\": 79.0}, {\"site\": 951, \"mutant\": \"E\", \"log2 fold change IC90\": 0.736698327341489, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.14571291524462862, \"functional effect\": 0.1434, \"times_seen\": 34.0}, {\"site\": 951, \"mutant\": \"F\", \"log2 fold change IC90\": -0.1899877267097006, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.07665451643132508, \"functional effect\": 0.0385, \"times_seen\": 58.0}, {\"site\": 951, \"mutant\": \"G\", \"log2 fold change IC90\": 0.041758018132585104, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.09001194970434594, \"functional effect\": -0.1723, \"times_seen\": 66.0}, {\"site\": 951, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 951, \"mutant\": \"I\", \"log2 fold change IC90\": 0.5689131985600878, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.129714847831603, \"functional effect\": 0.2681, \"times_seen\": 37.0}, {\"site\": 951, \"mutant\": \"K\", \"log2 fold change IC90\": 0.017097584295749067, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08848642282375647, \"functional effect\": 0.2298, \"times_seen\": 59.0}, {\"site\": 951, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0024742964136235937, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08759404665362334, \"functional effect\": 0.1357, \"times_seen\": 179.0}, {\"site\": 951, \"mutant\": \"M\", \"log2 fold change IC90\": -0.08969614326928466, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08217288279747066, \"functional effect\": 0.3673, \"times_seen\": 35.0}, {\"site\": 951, \"mutant\": \"N\", \"log2 fold change IC90\": -0.12397136314481617, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.0802436461071692, \"functional effect\": 0.1962, \"times_seen\": 63.0}, {\"site\": 951, \"mutant\": \"P\", \"log2 fold change IC90\": 0.029055239274058318, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08922288283025154, \"functional effect\": -2.4186, \"times_seen\": 16.0}, {\"site\": 951, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0948654388356288, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.09338714434693952, \"functional effect\": 0.3579, \"times_seen\": 114.0}, {\"site\": 951, \"mutant\": \"R\", \"log2 fold change IC90\": -0.022052668228068003, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08611746519608908, \"functional effect\": 0.2391, \"times_seen\": 181.0}, {\"site\": 951, \"mutant\": \"S\", \"log2 fold change IC90\": 0.3449220843022388, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.11106101708196052, \"functional effect\": 0.157, \"times_seen\": 161.0}, {\"site\": 951, \"mutant\": \"T\", \"log2 fold change IC90\": 0.009820439045573493, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08804120936562053, \"functional effect\": 0.3262, \"times_seen\": 66.0}, {\"site\": 951, \"mutant\": \"V\", \"log2 fold change IC90\": -0.5470235337904465, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.0598493255735476, \"functional effect\": 0.3553, \"times_seen\": 113.0}, {\"site\": 951, \"mutant\": \"W\", \"log2 fold change IC90\": -0.028074222830547366, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08575877516307036, \"functional effect\": 0.1018, \"times_seen\": 29.0}, {\"site\": 951, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.060041922894952485, \"epitope\": \"all\", \"reference_site\": \"954\", \"IC90\": 0.08387940343675092, \"functional effect\": 0.0851, \"times_seen\": 67.0}, {\"site\": 952, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"D\", \"log2 fold change IC90\": -0.01376397480115759, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08661365855340783, \"functional effect\": -2.0274, \"times_seen\": 13.0}, {\"site\": 952, \"mutant\": \"F\", \"log2 fold change IC90\": -0.06149379127552917, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08379503314876062, \"functional effect\": -1.5595, \"times_seen\": 9.0}, {\"site\": 952, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"H\", \"log2 fold change IC90\": 0.004202883219716323, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08769906168085644, \"functional effect\": -0.2737, \"times_seen\": 12.0}, {\"site\": 952, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": null, \"functional effect\": -3.1284, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"K\", \"log2 fold change IC90\": -0.06302076222631638, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08370639009656143, \"functional effect\": -2.2184, \"times_seen\": 2.0}, {\"site\": 952, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 952, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0007368645110340402, \"epitope\": \"all\", \"reference_site\": \"955\", \"IC90\": 0.08748862098604945, \"functional effect\": -0.1368, \"times_seen\": 1.0}, {\"site\": 953, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 953, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 953, \"mutant\": \"D\", \"log2 fold change IC90\": -0.012827223120232862, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08666991565179308, \"functional effect\": -1.2581, \"times_seen\": 5.0}, {\"site\": 953, \"mutant\": \"F\", \"log2 fold change IC90\": -0.02393725808201148, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08600504355523389, \"functional effect\": -0.3312, \"times_seen\": 8.0}, {\"site\": 953, \"mutant\": \"H\", \"log2 fold change IC90\": 0.004946225523151657, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08774425988151253, \"functional effect\": -0.1056, \"times_seen\": 10.0}, {\"site\": 953, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02741732856913069, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08579783211748197, \"functional effect\": -0.9177, \"times_seen\": 9.0}, {\"site\": 953, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": null, \"functional effect\": -2.0292, \"times_seen\": null}, {\"site\": 953, \"mutant\": \"S\", \"log2 fold change IC90\": 0.006818929416607985, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.0878582310996375, \"functional effect\": -0.1719, \"times_seen\": 16.0}, {\"site\": 953, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02611943506415958, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08587505325624091, \"functional effect\": -0.122, \"times_seen\": 17.0}, {\"site\": 953, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01918406652473536, \"epitope\": \"all\", \"reference_site\": \"956\", \"IC90\": 0.08628886834266387, \"functional effect\": 0.3986, \"times_seen\": 8.0}, {\"site\": 954, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": null, \"functional effect\": -2.7546, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"E\", \"log2 fold change IC90\": 0.13091310016795635, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.09574994271220785, \"functional effect\": -0.0619, \"times_seen\": 32.0}, {\"site\": 954, \"mutant\": \"H\", \"log2 fold change IC90\": -0.065332865890709, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.08357234731967095, \"functional effect\": -0.0952, \"times_seen\": 27.0}, {\"site\": 954, \"mutant\": \"K\", \"log2 fold change IC90\": 0.025591131890778177, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.08900890353007791, \"functional effect\": -0.5593, \"times_seen\": 17.0}, {\"site\": 954, \"mutant\": \"L\", \"log2 fold change IC90\": 0.1522239687315418, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.09717481745465026, \"functional effect\": -0.2516, \"times_seen\": 77.0}, {\"site\": 954, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": null, \"functional effect\": -3.0958, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 954, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0591783199962783, \"epitope\": \"all\", \"reference_site\": \"957\", \"IC90\": 0.09110541741024121, \"functional effect\": -0.1634, \"times_seen\": 50.0}, {\"site\": 955, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004558162607864947, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08716810589416568, \"functional effect\": -0.3862, \"times_seen\": 1.0}, {\"site\": 955, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": null, \"functional effect\": -2.0828, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"L\", \"log2 fold change IC90\": 0.09344579963781778, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.09329529482943873, \"functional effect\": -0.9988, \"times_seen\": 9.0}, {\"site\": 955, \"mutant\": \"M\", \"log2 fold change IC90\": 0.026789229093741495, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08908285236066697, \"functional effect\": -1.2735, \"times_seen\": 3.0}, {\"site\": 955, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": null, \"functional effect\": -2.4826, \"times_seen\": null}, {\"site\": 955, \"mutant\": \"S\", \"log2 fold change IC90\": 0.007989284207411088, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08792953308476403, \"functional effect\": -0.54, \"times_seen\": 39.0}, {\"site\": 955, \"mutant\": \"T\", \"log2 fold change IC90\": 0.014336214718645228, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.08831721864900155, \"functional effect\": -1.6606, \"times_seen\": 13.0}, {\"site\": 955, \"mutant\": \"V\", \"log2 fold change IC90\": -0.018985169751348053, \"epitope\": \"all\", \"reference_site\": \"958\", \"IC90\": 0.0863007653549344, \"functional effect\": -2.7862, \"times_seen\": 5.0}, {\"site\": 956, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 956, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 956, \"mutant\": \"M\", \"log2 fold change IC90\": -1.314445947459156, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.03515945179581703, \"functional effect\": -0.2794, \"times_seen\": 2.0}, {\"site\": 956, \"mutant\": \"P\", \"log2 fold change IC90\": -0.012286734144738604, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08670239161413489, \"functional effect\": -2.7605, \"times_seen\": 2.0}, {\"site\": 956, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01272353796595417, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.0866761447620695, \"functional effect\": -1.3264, \"times_seen\": 1.0}, {\"site\": 956, \"mutant\": \"R\", \"log2 fold change IC90\": -0.016034486361053955, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08647745329931024, \"functional effect\": -0.2295, \"times_seen\": 1.0}, {\"site\": 956, \"mutant\": \"V\", \"log2 fold change IC90\": -0.010816740239332604, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08679077962236056, \"functional effect\": -1.2439, \"times_seen\": 1.0}, {\"site\": 956, \"mutant\": \"W\", \"log2 fold change IC90\": -0.09470282294858394, \"epitope\": \"all\", \"reference_site\": \"959\", \"IC90\": 0.08188820707696699, \"functional effect\": -2.1038, \"times_seen\": 6.0}, {\"site\": 957, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"A\", \"log2 fold change IC90\": -1.534450064761447, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.030186603926422362, \"functional effect\": 0.1938, \"times_seen\": 9.0}, {\"site\": 957, \"mutant\": \"D\", \"log2 fold change IC90\": -0.03844186298819015, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08514469595205355, \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 957, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0046834149929583044, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08716053843262342, \"functional effect\": -0.9805, \"times_seen\": 1.0}, {\"site\": 957, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": null, \"functional effect\": -0.4506, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"K\", \"log2 fold change IC90\": -0.034914208535135854, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08535314512238536, \"functional effect\": -0.3297, \"times_seen\": 11.0}, {\"site\": 957, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 957, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02893294121538286, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.0857077451654376, \"functional effect\": -0.0866, \"times_seen\": 21.0}, {\"site\": 957, \"mutant\": \"T\", \"log2 fold change IC90\": -0.033793629719345734, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08541946688696148, \"functional effect\": -0.2975, \"times_seen\": 11.0}, {\"site\": 957, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.011241127750708103, \"epitope\": \"all\", \"reference_site\": \"960\", \"IC90\": 0.08676525274036542, \"functional effect\": -1.2786, \"times_seen\": 1.0}, {\"site\": 958, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 958, \"mutant\": \"A\", \"log2 fold change IC90\": -0.07946793537211845, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.08275753008529971, \"functional effect\": -0.4658, \"times_seen\": 43.0}, {\"site\": 958, \"mutant\": \"I\", \"log2 fold change IC90\": 0.094075457504106, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.09333602203496846, \"functional effect\": -0.425, \"times_seen\": 4.0}, {\"site\": 958, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05332879917412162, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.08427061912557277, \"functional effect\": -0.2616, \"times_seen\": 24.0}, {\"site\": 958, \"mutant\": \"N\", \"log2 fold change IC90\": -2.108174111704092, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.02028178194184347, \"functional effect\": 0.2815, \"times_seen\": 5.0}, {\"site\": 958, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": null, \"functional effect\": -2.8991, \"times_seen\": null}, {\"site\": 958, \"mutant\": \"R\", \"log2 fold change IC90\": -0.042771592316104036, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.0848895478858101, \"functional effect\": -0.9293, \"times_seen\": 10.0}, {\"site\": 958, \"mutant\": \"S\", \"log2 fold change IC90\": -0.023729708683213415, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.08601741732698134, \"functional effect\": -0.2061, \"times_seen\": 27.0}, {\"site\": 958, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"961\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0028112215534408535, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08727372057446697, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 959, \"mutant\": \"K\", \"log2 fold change IC90\": -0.00826470460460352, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08694444285352997, \"functional effect\": -2.8737, \"times_seen\": 2.0}, {\"site\": 959, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"M\", \"log2 fold change IC90\": 0.017756567408689385, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08852685020180794, \"functional effect\": -2.8218, \"times_seen\": 2.0}, {\"site\": 959, \"mutant\": \"P\", \"log2 fold change IC90\": -0.009858607257024752, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.08684843888209358, \"functional effect\": -2.7538, \"times_seen\": 3.0}, {\"site\": 959, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": null, \"functional effect\": -2.8229, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 959, \"mutant\": \"T\", \"log2 fold change IC90\": 0.016759194475436997, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.088465670417647, \"functional effect\": -2.7581, \"times_seen\": 3.0}, {\"site\": 959, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0043639058702653645, \"epitope\": \"all\", \"reference_site\": \"962\", \"IC90\": 0.0871798437399654, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 960, \"mutant\": \"-\", \"log2 fold change IC90\": -0.003911325032056978, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08720719679452428, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 960, \"mutant\": \"A\", \"log2 fold change IC90\": -0.006997691537725001, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.087020833309471, \"functional effect\": -2.5528, \"times_seen\": 3.0}, {\"site\": 960, \"mutant\": \"I\", \"log2 fold change IC90\": -0.11134126248459987, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08094922459823822, \"functional effect\": -0.3528, \"times_seen\": 30.0}, {\"site\": 960, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02388264240485471, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08890355848949864, \"functional effect\": -0.5852, \"times_seen\": 26.0}, {\"site\": 960, \"mutant\": \"M\", \"log2 fold change IC90\": -0.031437458216565926, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.08555908568795641, \"functional effect\": -0.4396, \"times_seen\": 31.0}, {\"site\": 960, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": null, \"functional effect\": -0.911, \"times_seen\": null}, {\"site\": 960, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"963\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 961, \"mutant\": \"-\", \"log2 fold change IC90\": -0.002917467365442897, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08726729362655092, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 961, \"mutant\": \"E\", \"log2 fold change IC90\": -5.140805775221343e-05, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08744083123100185, \"functional effect\": -0.1421, \"times_seen\": 1.0}, {\"site\": 961, \"mutant\": \"H\", \"log2 fold change IC90\": -0.021996447932887738, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08612082116773417, \"functional effect\": -0.1207, \"times_seen\": 3.0}, {\"site\": 961, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03959479054357149, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08507667987841945, \"functional effect\": -0.0698, \"times_seen\": 13.0}, {\"site\": 961, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 961, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04107310928830781, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08498954709496302, \"functional effect\": 0.0106, \"times_seen\": 11.0}, {\"site\": 961, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0006847352263402896, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.08740245409726018, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 961, \"mutant\": \"N\", \"log2 fold change IC90\": 0.10639012066776397, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.0941361365437587, \"functional effect\": -0.0124, \"times_seen\": 20.0}, {\"site\": 961, \"mutant\": \"R\", \"log2 fold change IC90\": 0.05409064928571458, \"epitope\": \"all\", \"reference_site\": \"964\", \"IC90\": 0.09078469957471082, \"functional effect\": -0.1502, \"times_seen\": 22.0}, {\"site\": 962, \"mutant\": \"*\", \"log2 fold change IC90\": -0.01226880969895122, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08670346883553535, \"functional effect\": -2.4019, \"times_seen\": 2.0}, {\"site\": 962, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004194050610707279, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08719010843645787, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 962, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": -0.2766, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": -0.712, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"K\", \"log2 fold change IC90\": -0.11067232683745312, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08098676709765444, \"functional effect\": -0.4059, \"times_seen\": 30.0}, {\"site\": 962, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": 0.0708, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02458339059829371, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08596653353654361, \"functional effect\": -0.3547, \"times_seen\": 12.0}, {\"site\": 962, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": null, \"functional effect\": -2.2766, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 962, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0046299860180841635, \"epitope\": \"all\", \"reference_site\": \"965\", \"IC90\": 0.08716376640826562, \"functional effect\": -2.2174, \"times_seen\": 1.0}, {\"site\": 963, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0031297585778877015, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": 0.08725445327147585, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 963, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -2.6953, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -1.7631, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -2.6644, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -3.0577, \"times_seen\": null}, {\"site\": 963, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"966\", \"IC90\": null, \"functional effect\": -2.7218, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0032148863144262807, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08724930488268827, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 964, \"mutant\": \"A\", \"log2 fold change IC90\": -0.027555803512803977, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08578959733503079, \"functional effect\": -0.1633, \"times_seen\": 4.0}, {\"site\": 964, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": null, \"functional effect\": -1.7587, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0026396262209192724, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.0872841015997897, \"functional effect\": -1.6437, \"times_seen\": 1.0}, {\"site\": 964, \"mutant\": \"G\", \"log2 fold change IC90\": -0.021132421258314615, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08617241417336408, \"functional effect\": -0.3437, \"times_seen\": 5.0}, {\"site\": 964, \"mutant\": \"N\", \"log2 fold change IC90\": -0.030563509335911364, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08561093096212681, \"functional effect\": -2.0275, \"times_seen\": 10.0}, {\"site\": 964, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": null, \"functional effect\": -3.2791, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"R\", \"log2 fold change IC90\": 0.016138564902217635, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08842762176438777, \"functional effect\": -1.1687, \"times_seen\": 4.0}, {\"site\": 964, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 964, \"mutant\": \"T\", \"log2 fold change IC90\": 0.002829143312896768, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08761559403392383, \"functional effect\": -0.681, \"times_seen\": 24.0}, {\"site\": 964, \"mutant\": \"W\", \"log2 fold change IC90\": -0.007857055846586677, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08696901339753342, \"functional effect\": -2.4424, \"times_seen\": 3.0}, {\"site\": 964, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0052318409919541115, \"epitope\": \"all\", \"reference_site\": \"967\", \"IC90\": 0.08712741152804206, \"functional effect\": -2.1403, \"times_seen\": 1.0}, {\"site\": 965, \"mutant\": \"-\", \"log2 fold change IC90\": -0.006999407164470824, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.0870207298259377, \"functional effect\": -0.3763, \"times_seen\": 1.0}, {\"site\": 965, \"mutant\": \"C\", \"log2 fold change IC90\": 0.037181349554274275, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08972685679322177, \"functional effect\": -0.6781, \"times_seen\": 52.0}, {\"site\": 965, \"mutant\": \"F\", \"log2 fold change IC90\": -1.9645313097554538, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.02240510075009034, \"functional effect\": 0.3242, \"times_seen\": 8.0}, {\"site\": 965, \"mutant\": \"G\", \"log2 fold change IC90\": -0.025024156541794455, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08594027342500661, \"functional effect\": -1.0771, \"times_seen\": 10.0}, {\"site\": 965, \"mutant\": \"I\", \"log2 fold change IC90\": -0.026187771200549294, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08587098570890475, \"functional effect\": -0.0723, \"times_seen\": 4.0}, {\"site\": 965, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02165709400553116, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08614108108099916, \"functional effect\": 0.3441, \"times_seen\": 23.0}, {\"site\": 965, \"mutant\": \"P\", \"log2 fold change IC90\": -0.006610227943093712, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08704420757226486, \"functional effect\": -2.4785, \"times_seen\": 3.0}, {\"site\": 965, \"mutant\": \"R\", \"log2 fold change IC90\": -0.02747402732518566, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08579446027892618, \"functional effect\": -1.1234, \"times_seen\": 5.0}, {\"site\": 965, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 965, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08560874207353869, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.0824060227009469, \"functional effect\": -0.0446, \"times_seen\": 21.0}, {\"site\": 965, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01393314894795017, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": 0.08660350260756164, \"functional effect\": -0.0248, \"times_seen\": 19.0}, {\"site\": 965, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"968\", \"IC90\": null, \"functional effect\": -0.1442, \"times_seen\": null}, {\"site\": 966, \"mutant\": \"*\", \"log2 fold change IC90\": 0.03391545106878954, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08952396750303919, \"functional effect\": -2.7391, \"times_seen\": 2.0}, {\"site\": 966, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 966, \"mutant\": \"A\", \"log2 fold change IC90\": 0.005022655262130984, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08774890843739717, \"functional effect\": -2.4298, \"times_seen\": 7.0}, {\"site\": 966, \"mutant\": \"C\", \"log2 fold change IC90\": 0.03830615057314559, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08979683985303259, \"functional effect\": -1.6117, \"times_seen\": 17.0}, {\"site\": 966, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0028768052010159453, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08726975327807054, \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 966, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0554331055856333, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08414779210056662, \"functional effect\": -2.5324, \"times_seen\": 9.0}, {\"site\": 966, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0097879797003304, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08685269067683385, \"functional effect\": -2.4857, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"G\", \"log2 fold change IC90\": -0.020988970791993015, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08618098291951762, \"functional effect\": -2.262, \"times_seen\": 12.0}, {\"site\": 966, \"mutant\": \"H\", \"log2 fold change IC90\": -0.022600455998650404, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08608477281265346, \"functional effect\": -2.3963, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06254995591070972, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.09131858340007572, \"functional effect\": -2.8676, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 966, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005912157358928981, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08708633546626986, \"functional effect\": -2.2689, \"times_seen\": 10.0}, {\"site\": 966, \"mutant\": \"M\", \"log2 fold change IC90\": 0.017042346976996664, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0884830349565806, \"functional effect\": -2.9869, \"times_seen\": 4.0}, {\"site\": 966, \"mutant\": \"N\", \"log2 fold change IC90\": -0.18014582759000786, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.07717923243959005, \"functional effect\": -1.4827, \"times_seen\": 55.0}, {\"site\": 966, \"mutant\": \"P\", \"log2 fold change IC90\": -0.4971158801879259, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.061955941577100895, \"functional effect\": -1.4039, \"times_seen\": 28.0}, {\"site\": 966, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.009400421087680537, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08801558128377937, \"functional effect\": -2.3216, \"times_seen\": 24.0}, {\"site\": 966, \"mutant\": \"R\", \"log2 fold change IC90\": -0.42003115437040306, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.0653563479501994, \"functional effect\": 0.1338, \"times_seen\": 167.0}, {\"site\": 966, \"mutant\": \"S\", \"log2 fold change IC90\": 0.21053814992170408, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.10118311635451586, \"functional effect\": -0.5279, \"times_seen\": 99.0}, {\"site\": 966, \"mutant\": \"T\", \"log2 fold change IC90\": 0.05310955192943441, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.09072298289325563, \"functional effect\": 0.1531, \"times_seen\": 71.0}, {\"site\": 966, \"mutant\": \"V\", \"log2 fold change IC90\": 0.012356220033956066, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08819609278606622, \"functional effect\": -2.642, \"times_seen\": 5.0}, {\"site\": 966, \"mutant\": \"W\", \"log2 fold change IC90\": 0.008186048392518684, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08794152630739628, \"functional effect\": -2.8316, \"times_seen\": 6.0}, {\"site\": 966, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005766748425311998, \"epitope\": \"all\", \"reference_site\": \"969\", \"IC90\": 0.08709511332229103, \"functional effect\": -2.8978, \"times_seen\": 1.0}, {\"site\": 967, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 967, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 967, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01568857367672517, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.08649819034602987, \"functional effect\": -2.9828, \"times_seen\": 1.0}, {\"site\": 967, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": null, \"functional effect\": -2.7936, \"times_seen\": null}, {\"site\": 967, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00837062390231704, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.0869380598300778, \"functional effect\": -2.0329, \"times_seen\": 2.0}, {\"site\": 967, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0008777194351430322, \"epitope\": \"all\", \"reference_site\": \"970\", \"IC90\": 0.08739076336229222, \"functional effect\": -0.7589, \"times_seen\": 1.0}, {\"site\": 968, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -2.8947, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -2.792, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -2.8535, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": null, \"functional effect\": -3.0508, \"times_seen\": null}, {\"site\": 968, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.008279563135620158, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.08694354740437979, \"functional effect\": -3.0212, \"times_seen\": 1.0}, {\"site\": 968, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01804744257057845, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.08635687761514595, \"functional effect\": -1.9913, \"times_seen\": 4.0}, {\"site\": 968, \"mutant\": \"V\", \"log2 fold change IC90\": 0.020463170520504833, \"epitope\": \"all\", \"reference_site\": \"971\", \"IC90\": 0.08869308904118443, \"functional effect\": -2.7955, \"times_seen\": 5.0}, {\"site\": 969, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": null, \"functional effect\": -0.9846, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"C\", \"log2 fold change IC90\": 0.052775825722266766, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.09070199915478062, \"functional effect\": -0.2237, \"times_seen\": 20.0}, {\"site\": 969, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": null, \"functional effect\": -2.3768, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": null, \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 969, \"mutant\": \"M\", \"log2 fold change IC90\": 0.009204976406925157, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08800365845078657, \"functional effect\": -2.2134, \"times_seen\": 5.0}, {\"site\": 969, \"mutant\": \"S\", \"log2 fold change IC90\": -0.057832974697740014, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08400793176167741, \"functional effect\": -2.0949, \"times_seen\": 17.0}, {\"site\": 969, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02441049697349853, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08597683644589647, \"functional effect\": -1.7998, \"times_seen\": 9.0}, {\"site\": 969, \"mutant\": \"V\", \"log2 fold change IC90\": -0.019370853928010065, \"epitope\": \"all\", \"reference_site\": \"972\", \"IC90\": 0.08627769714580624, \"functional effect\": -2.9983, \"times_seen\": 5.0}, {\"site\": 970, \"mutant\": \"F\", \"log2 fold change IC90\": -0.01539091590695644, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": 0.08651603854952022, \"functional effect\": -1.6201, \"times_seen\": 9.0}, {\"site\": 970, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 970, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 970, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": null, \"functional effect\": -2.0482, \"times_seen\": null}, {\"site\": 970, \"mutant\": \"T\", \"log2 fold change IC90\": 0.028574226205403216, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": 0.08919313973303311, \"functional effect\": -0.172, \"times_seen\": 5.0}, {\"site\": 970, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"973\", \"IC90\": null, \"functional effect\": -0.1562, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"-\", \"log2 fold change IC90\": -0.005041410212003586, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08713891280553772, \"functional effect\": -2.1772, \"times_seen\": 1.0}, {\"site\": 971, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": null, \"functional effect\": -2.9942, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": null, \"functional effect\": -1.0597, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0009090524107076524, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08738886539852243, \"functional effect\": -2.9803, \"times_seen\": 1.0}, {\"site\": 971, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004521903435222506, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08717029671275826, \"functional effect\": -0.3972, \"times_seen\": 2.0}, {\"site\": 971, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 971, \"mutant\": \"T\", \"log2 fold change IC90\": 0.002916327255652498, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": 0.08762088891851856, \"functional effect\": 0.0648, \"times_seen\": 1.0}, {\"site\": 971, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"974\", \"IC90\": null, \"functional effect\": -2.9825, \"times_seen\": null}, {\"site\": 972, \"mutant\": \"A\", \"log2 fold change IC90\": -0.005453503719251288, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08711402587443814, \"functional effect\": 0.191, \"times_seen\": 2.0}, {\"site\": 972, \"mutant\": \"F\", \"log2 fold change IC90\": -0.007255869645265239, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08700526185239996, \"functional effect\": -0.7476, \"times_seen\": 1.0}, {\"site\": 972, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01161459347395285, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08674279501148162, \"functional effect\": -2.6768, \"times_seen\": 3.0}, {\"site\": 972, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0319053445832795, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08553134216777424, \"functional effect\": 0.4086, \"times_seen\": 21.0}, {\"site\": 972, \"mutant\": \"P\", \"log2 fold change IC90\": -0.010798677492820588, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08679186626203235, \"functional effect\": -0.1918, \"times_seen\": 6.0}, {\"site\": 972, \"mutant\": \"R\", \"log2 fold change IC90\": -0.02718028319926665, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08581193048837975, \"functional effect\": -2.952, \"times_seen\": 4.0}, {\"site\": 972, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 972, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 972, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0047177366390076, \"epitope\": \"all\", \"reference_site\": \"975\", \"IC90\": 0.08715846491224571, \"functional effect\": -2.3569, \"times_seen\": 1.0}, {\"site\": 973, \"mutant\": \"A\", \"log2 fold change IC90\": -0.019230098911416096, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08628611514876437, \"functional effect\": 0.309, \"times_seen\": 27.0}, {\"site\": 973, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0329600246954966, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08546883745420371, \"functional effect\": 0.0741, \"times_seen\": 4.0}, {\"site\": 973, \"mutant\": \"F\", \"log2 fold change IC90\": -0.1438395368563095, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.07914613976840065, \"functional effect\": -0.2778, \"times_seen\": 40.0}, {\"site\": 973, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05667456512302928, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08407541287854584, \"functional effect\": -0.3156, \"times_seen\": 25.0}, {\"site\": 973, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0306718235218425, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08560450373395535, \"functional effect\": -0.3747, \"times_seen\": 18.0}, {\"site\": 973, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015486512641230523, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08651030596120331, \"functional effect\": -0.9486, \"times_seen\": 4.0}, {\"site\": 973, \"mutant\": \"M\", \"log2 fold change IC90\": -0.09880133906167789, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.08165590305540266, \"functional effect\": -0.3943, \"times_seen\": 19.0}, {\"site\": 973, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"976\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"M\", \"log2 fold change IC90\": -0.004549155617249068, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.08716865010118129, \"functional effect\": 0.0639, \"times_seen\": 6.0}, {\"site\": 974, \"mutant\": \"P\", \"log2 fold change IC90\": 0.04542144743257178, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.09024080710565398, \"functional effect\": -2.6936, \"times_seen\": 14.0}, {\"site\": 974, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": null, \"functional effect\": -3.0155, \"times_seen\": null}, {\"site\": 974, \"mutant\": \"S\", \"log2 fold change IC90\": -0.009186228489358317, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.08688892467742192, \"functional effect\": -2.8464, \"times_seen\": 2.0}, {\"site\": 974, \"mutant\": \"V\", \"log2 fold change IC90\": -0.057278790392524336, \"epitope\": \"all\", \"reference_site\": \"977\", \"IC90\": 0.08404020803553004, \"functional effect\": 0.4444, \"times_seen\": 12.0}, {\"site\": 975, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": null, \"functional effect\": -0.6369, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"F\", \"log2 fold change IC90\": -0.024897030274859195, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08594784657608595, \"functional effect\": -0.7606, \"times_seen\": 8.0}, {\"site\": 975, \"mutant\": \"H\", \"log2 fold change IC90\": -0.013033491473472306, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08665752496468562, \"functional effect\": -0.2445, \"times_seen\": 3.0}, {\"site\": 975, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": null, \"functional effect\": -2.6303, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 975, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0033311714872531115, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08764608776224658, \"functional effect\": 0.0876, \"times_seen\": 16.0}, {\"site\": 975, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.005173365491871708, \"epitope\": \"all\", \"reference_site\": \"978\", \"IC90\": 0.08713094305900938, \"functional effect\": -2.0323, \"times_seen\": 1.0}, {\"site\": 976, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004716676904940313, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08715852893466614, \"functional effect\": 0.2967, \"times_seen\": 7.0}, {\"site\": 976, \"mutant\": \"G\", \"log2 fold change IC90\": -0.01719508760647616, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08640791297550454, \"functional effect\": -2.5281, \"times_seen\": 3.0}, {\"site\": 976, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": null, \"functional effect\": -1.9653, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"N\", \"log2 fold change IC90\": 0.021184412530195047, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08873744018442221, \"functional effect\": -2.4352, \"times_seen\": 2.0}, {\"site\": 976, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": null, \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 976, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004669122081554189, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08716140194430778, \"functional effect\": -0.0933, \"times_seen\": 1.0}, {\"site\": 976, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.02171643994391731, \"epitope\": \"all\", \"reference_site\": \"979\", \"IC90\": 0.08877017021784284, \"functional effect\": -2.3506, \"times_seen\": 5.0}, {\"site\": 977, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009140985345677262, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.08689164957050957, \"functional effect\": -2.741, \"times_seen\": 2.0}, {\"site\": 977, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"L\", \"log2 fold change IC90\": -0.051042974802934744, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.084404244397117, \"functional effect\": -1.4023, \"times_seen\": 3.0}, {\"site\": 977, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -3.0261, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -2.7277, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": null, \"functional effect\": -3.1298, \"times_seen\": null}, {\"site\": 977, \"mutant\": \"V\", \"log2 fold change IC90\": -0.014861416961889069, \"epitope\": \"all\", \"reference_site\": \"980\", \"IC90\": 0.08654779755437589, \"functional effect\": -1.8607, \"times_seen\": 3.0}, {\"site\": 978, \"mutant\": \"*\", \"log2 fold change IC90\": -0.010853566032707814, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08678856425567864, \"functional effect\": -2.6138, \"times_seen\": 4.0}, {\"site\": 978, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": null, \"functional effect\": -1.8075, \"times_seen\": null}, {\"site\": 978, \"mutant\": \"A\", \"log2 fold change IC90\": -0.45966117328336437, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.06358547966974916, \"functional effect\": 0.1042, \"times_seen\": 108.0}, {\"site\": 978, \"mutant\": \"C\", \"log2 fold change IC90\": -0.10000199298544399, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08158797484269603, \"functional effect\": 0.1214, \"times_seen\": 69.0}, {\"site\": 978, \"mutant\": \"D\", \"log2 fold change IC90\": -0.8254338924119142, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.049345708825634646, \"functional effect\": -1.0959, \"times_seen\": 48.0}, {\"site\": 978, \"mutant\": \"E\", \"log2 fold change IC90\": -0.07502628069557152, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08301270999499506, \"functional effect\": 0.4195, \"times_seen\": 50.0}, {\"site\": 978, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 978, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0386653124569741, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08513150947587703, \"functional effect\": -1.8415, \"times_seen\": 45.0}, {\"site\": 978, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03188104197938618, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08939781470242075, \"functional effect\": -0.8577, \"times_seen\": 43.0}, {\"site\": 978, \"mutant\": \"I\", \"log2 fold change IC90\": -0.7342802739458233, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.05256411601240566, \"functional effect\": 0.4444, \"times_seen\": 120.0}, {\"site\": 978, \"mutant\": \"K\", \"log2 fold change IC90\": 0.06658575958077258, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.09157439618655507, \"functional effect\": -2.1794, \"times_seen\": 22.0}, {\"site\": 978, \"mutant\": \"L\", \"log2 fold change IC90\": 0.10347946415199687, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.09394640708607307, \"functional effect\": 0.2322, \"times_seen\": 117.0}, {\"site\": 978, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05891109430279114, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08394517645818554, \"functional effect\": -0.1087, \"times_seen\": 37.0}, {\"site\": 978, \"mutant\": \"N\", \"log2 fold change IC90\": -0.06270599449340533, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08372465517990817, \"functional effect\": -0.4181, \"times_seen\": 48.0}, {\"site\": 978, \"mutant\": \"P\", \"log2 fold change IC90\": 0.3497685371515446, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.11143473228644417, \"functional effect\": -2.6849, \"times_seen\": 38.0}, {\"site\": 978, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02243091322560371, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08609488992563366, \"functional effect\": -0.5073, \"times_seen\": 24.0}, {\"site\": 978, \"mutant\": \"R\", \"log2 fold change IC90\": -0.021969152948311775, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08612245054099436, \"functional effect\": -2.2984, \"times_seen\": 48.0}, {\"site\": 978, \"mutant\": \"S\", \"log2 fold change IC90\": -0.18911646640616642, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.07670082296586776, \"functional effect\": 0.4298, \"times_seen\": 154.0}, {\"site\": 978, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08257590755892531, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.08257943891294513, \"functional effect\": 0.4444, \"times_seen\": 89.0}, {\"site\": 978, \"mutant\": \"V\", \"log2 fold change IC90\": -0.7689318536826975, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.0513166385117636, \"functional effect\": 0.4444, \"times_seen\": 124.0}, {\"site\": 978, \"mutant\": \"W\", \"log2 fold change IC90\": 0.23058076380480833, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.1025986105038537, \"functional effect\": 0.3058, \"times_seen\": 44.0}, {\"site\": 978, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.5278753122489812, \"epitope\": \"all\", \"reference_site\": \"981\", \"IC90\": 0.1260770550247075, \"functional effect\": 0.3651, \"times_seen\": 89.0}, {\"site\": 979, \"mutant\": \"*\", \"log2 fold change IC90\": 0.02794643679809628, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08915433574085793, \"functional effect\": -2.4364, \"times_seen\": 3.0}, {\"site\": 979, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 979, \"mutant\": \"A\", \"log2 fold change IC90\": 0.5765699846502338, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.1304051108984066, \"functional effect\": 0.2506, \"times_seen\": 109.0}, {\"site\": 979, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03108555828447594, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08557995767258623, \"functional effect\": -1.437, \"times_seen\": 54.0}, {\"site\": 979, \"mutant\": \"D\", \"log2 fold change IC90\": 0.00290899452903697, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08762044357257001, \"functional effect\": -1.5303, \"times_seen\": 31.0}, {\"site\": 979, \"mutant\": \"E\", \"log2 fold change IC90\": -1.6821821119260751, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.027248492416261903, \"functional effect\": -1.2212, \"times_seen\": 23.0}, {\"site\": 979, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0336767812178458, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08950915847958524, \"functional effect\": -2.1923, \"times_seen\": 12.0}, {\"site\": 979, \"mutant\": \"G\", \"log2 fold change IC90\": -0.15524584966068886, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.07852285747964749, \"functional effect\": -0.4425, \"times_seen\": 126.0}, {\"site\": 979, \"mutant\": \"H\", \"log2 fold change IC90\": 0.01812721492854226, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08854959684739205, \"functional effect\": -2.3799, \"times_seen\": 16.0}, {\"site\": 979, \"mutant\": \"I\", \"log2 fold change IC90\": -0.5265810937938914, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.060703404449505956, \"functional effect\": -1.0113, \"times_seen\": 44.0}, {\"site\": 979, \"mutant\": \"K\", \"log2 fold change IC90\": -0.069771253067077, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08331563579058063, \"functional effect\": -2.4314, \"times_seen\": 6.0}, {\"site\": 979, \"mutant\": \"L\", \"log2 fold change IC90\": 0.044865800426354775, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.09020605798810333, \"functional effect\": -1.0381, \"times_seen\": 68.0}, {\"site\": 979, \"mutant\": \"M\", \"log2 fold change IC90\": -0.025104044172039566, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08593551470988736, \"functional effect\": -0.3015, \"times_seen\": 32.0}, {\"site\": 979, \"mutant\": \"N\", \"log2 fold change IC90\": -0.27664853432315567, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.07218554599648076, \"functional effect\": -1.2317, \"times_seen\": 79.0}, {\"site\": 979, \"mutant\": \"P\", \"log2 fold change IC90\": 0.1971651846743911, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.10024953976832679, \"functional effect\": -1.592, \"times_seen\": 72.0}, {\"site\": 979, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.006743508207867123, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.0870361665526172, \"functional effect\": -0.6221, \"times_seen\": 29.0}, {\"site\": 979, \"mutant\": \"R\", \"log2 fold change IC90\": -0.07522994835872827, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08300099177954481, \"functional effect\": -2.7336, \"times_seen\": 29.0}, {\"site\": 979, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 979, \"mutant\": \"T\", \"log2 fold change IC90\": 0.036296386806955266, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08967183437021495, \"functional effect\": -0.4339, \"times_seen\": 74.0}, {\"site\": 979, \"mutant\": \"V\", \"log2 fold change IC90\": 0.022377120206495557, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.08881083170818063, \"functional effect\": -0.4688, \"times_seen\": 63.0}, {\"site\": 979, \"mutant\": \"W\", \"log2 fold change IC90\": -0.016686723105328802, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.0864383660196327, \"functional effect\": -1.9806, \"times_seen\": 18.0}, {\"site\": 979, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.04618939899991627, \"epitope\": \"all\", \"reference_site\": \"982\", \"IC90\": 0.09028885538684316, \"functional effect\": -1.5874, \"times_seen\": 20.0}, {\"site\": 980, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": null, \"functional effect\": -0.6108, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": null, \"functional effect\": -2.6466, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"I\", \"log2 fold change IC90\": -0.022311923942836955, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08610199107409973, \"functional effect\": -1.4676, \"times_seen\": 5.0}, {\"site\": 980, \"mutant\": \"K\", \"log2 fold change IC90\": -0.7937182561277271, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.05044251706844781, \"functional effect\": -1.359, \"times_seen\": 21.0}, {\"site\": 980, \"mutant\": \"N\", \"log2 fold change IC90\": 0.010396493899712917, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08807637042964203, \"functional effect\": -2.8738, \"times_seen\": 3.0}, {\"site\": 980, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.009160618262601582, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08689046711345419, \"functional effect\": -2.0455, \"times_seen\": 8.0}, {\"site\": 980, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": null, \"functional effect\": -2.3742, \"times_seen\": null}, {\"site\": 980, \"mutant\": \"T\", \"log2 fold change IC90\": -0.010417515212101708, \"epitope\": \"all\", \"reference_site\": \"983\", \"IC90\": 0.08681479983792272, \"functional effect\": -3.1267, \"times_seen\": 1.0}, {\"site\": 981, \"mutant\": \"F\", \"log2 fold change IC90\": -0.08291110482261717, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08256025454911302, \"functional effect\": 0.0263, \"times_seen\": 15.0}, {\"site\": 981, \"mutant\": \"K\", \"log2 fold change IC90\": -0.004860799189495393, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08714982241073695, \"functional effect\": -1.2901, \"times_seen\": 1.0}, {\"site\": 981, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 981, \"mutant\": \"M\", \"log2 fold change IC90\": -0.030710074799725644, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08560223406631352, \"functional effect\": -0.1847, \"times_seen\": 8.0}, {\"site\": 981, \"mutant\": \"P\", \"log2 fold change IC90\": -0.030457789139745155, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.0856172047315561, \"functional effect\": -2.9773, \"times_seen\": 5.0}, {\"site\": 981, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0018629851922156238, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08755693840899341, \"functional effect\": -2.6755, \"times_seen\": 1.0}, {\"site\": 981, \"mutant\": \"R\", \"log2 fold change IC90\": -0.008067840482870871, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08695630773748338, \"functional effect\": -2.6018, \"times_seen\": 2.0}, {\"site\": 981, \"mutant\": \"V\", \"log2 fold change IC90\": 0.025189804309137608, \"epitope\": \"all\", \"reference_site\": \"984\", \"IC90\": 0.08898414655862666, \"functional effect\": -1.3383, \"times_seen\": 2.0}, {\"site\": 982, \"mutant\": \"A\", \"log2 fold change IC90\": -0.08059978096761036, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08269262931996683, \"functional effect\": -1.3752, \"times_seen\": 16.0}, {\"site\": 982, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 982, \"mutant\": \"E\", \"log2 fold change IC90\": -0.024190712974183567, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08598993538355053, \"functional effect\": -0.6096, \"times_seen\": 6.0}, {\"site\": 982, \"mutant\": \"G\", \"log2 fold change IC90\": -0.01206565118907881, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08671567916919397, \"functional effect\": -0.8612, \"times_seen\": 1.0}, {\"site\": 982, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0058161144577026525, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08779718220711627, \"functional effect\": -1.5046, \"times_seen\": 1.0}, {\"site\": 982, \"mutant\": \"N\", \"log2 fold change IC90\": -2.476343762617407, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.015713611107916935, \"functional effect\": -0.1631, \"times_seen\": 39.0}, {\"site\": 982, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 982, \"mutant\": \"T\", \"log2 fold change IC90\": 0.8229757764660373, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.15469281667574805, \"functional effect\": -0.6573, \"times_seen\": 31.0}, {\"site\": 982, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": null, \"functional effect\": -2.4547, \"times_seen\": null}, {\"site\": 982, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006323300842751445, \"epitope\": \"all\", \"reference_site\": \"985\", \"IC90\": 0.08706152088181324, \"functional effect\": -3.054, \"times_seen\": 1.0}, {\"site\": 983, \"mutant\": \"E\", \"log2 fold change IC90\": -0.006515747551091523, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08704990818113562, \"functional effect\": -0.7122, \"times_seen\": 3.0}, {\"site\": 983, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04729852557798995, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08462359630235898, \"functional effect\": -0.7656, \"times_seen\": 1.0}, {\"site\": 983, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 983, \"mutant\": \"M\", \"log2 fold change IC90\": 0.027619236044009766, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08913411798360496, \"functional effect\": -0.0602, \"times_seen\": 4.0}, {\"site\": 983, \"mutant\": \"N\", \"log2 fold change IC90\": 1.184862022171404, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.19879651293406783, \"functional effect\": -0.3265, \"times_seen\": 26.0}, {\"site\": 983, \"mutant\": \"P\", \"log2 fold change IC90\": 1.7061441365398777, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.28531875142430374, \"functional effect\": -2.5728, \"times_seen\": 12.0}, {\"site\": 983, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.09878773950376095, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.081656672788011, \"functional effect\": -0.5062, \"times_seen\": 26.0}, {\"site\": 983, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0971040832991629, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.0817520235123112, \"functional effect\": -0.1729, \"times_seen\": 92.0}, {\"site\": 983, \"mutant\": \"T\", \"log2 fold change IC90\": 0.016257507876091967, \"epitope\": \"all\", \"reference_site\": \"986\", \"IC90\": 0.08843491247905086, \"functional effect\": 0.0755, \"times_seen\": 12.0}, {\"site\": 984, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": null, \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 984, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": null, \"functional effect\": -2.6678, \"times_seen\": null}, {\"site\": 984, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": null, \"functional effect\": -2.3691, \"times_seen\": null}, {\"site\": 984, \"mutant\": \"F\", \"log2 fold change IC90\": 0.011091316760113604, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08811879950374493, \"functional effect\": -0.0256, \"times_seen\": 38.0}, {\"site\": 984, \"mutant\": \"G\", \"log2 fold change IC90\": 0.025979604318632353, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08903287405718885, \"functional effect\": -2.0631, \"times_seen\": 1.0}, {\"site\": 984, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0007462869391866806, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08748919238742954, \"functional effect\": -0.6662, \"times_seen\": 13.0}, {\"site\": 984, \"mutant\": \"L\", \"log2 fold change IC90\": 0.020171493002011466, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.0886751592885722, \"functional effect\": -2.2332, \"times_seen\": 10.0}, {\"site\": 984, \"mutant\": \"M\", \"log2 fold change IC90\": -0.003417449718378412, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.08723705539474341, \"functional effect\": -0.1031, \"times_seen\": 7.0}, {\"site\": 984, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"987\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": null, \"functional effect\": -1.4746, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": null, \"functional effect\": -2.3171, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"D\", \"log2 fold change IC90\": -0.02077458078699934, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08619379069505598, \"functional effect\": 0.1539, \"times_seen\": 8.0}, {\"site\": 985, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 985, \"mutant\": \"G\", \"log2 fold change IC90\": -0.059898258307492486, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08388775662267596, \"functional effect\": -1.0405, \"times_seen\": 23.0}, {\"site\": 985, \"mutant\": \"K\", \"log2 fold change IC90\": -0.8588235151797057, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.04821676997462332, \"functional effect\": -0.9251, \"times_seen\": 45.0}, {\"site\": 985, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04905290679786166, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08452075279609896, \"functional effect\": -1.4406, \"times_seen\": 15.0}, {\"site\": 985, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0020686233130944648, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08731865452931979, \"functional effect\": -0.801, \"times_seen\": 21.0}, {\"site\": 985, \"mutant\": \"V\", \"log2 fold change IC90\": -0.003363789960087728, \"epitope\": \"all\", \"reference_site\": \"988\", \"IC90\": 0.08724030015973526, \"functional effect\": -1.4355, \"times_seen\": 5.0}, {\"site\": 986, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 986, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01538505745503809, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08651638987191806, \"functional effect\": -2.014, \"times_seen\": 4.0}, {\"site\": 986, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": null, \"functional effect\": -2.5603, \"times_seen\": null}, {\"site\": 986, \"mutant\": \"G\", \"log2 fold change IC90\": -0.00021297538281711496, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08743103928623241, \"functional effect\": -1.1198, \"times_seen\": 1.0}, {\"site\": 986, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": null, \"functional effect\": -2.9982, \"times_seen\": null}, {\"site\": 986, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0006834057305667591, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08740253464182682, \"functional effect\": -3.2259, \"times_seen\": 1.0}, {\"site\": 986, \"mutant\": \"S\", \"log2 fold change IC90\": 0.8032775098611227, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.15259502620491303, \"functional effect\": -1.5174, \"times_seen\": 19.0}, {\"site\": 986, \"mutant\": \"T\", \"log2 fold change IC90\": -0.002565851837448911, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08728856511788953, \"functional effect\": -2.7458, \"times_seen\": 2.0}, {\"site\": 986, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005871479309364794, \"epitope\": \"all\", \"reference_site\": \"989\", \"IC90\": 0.08708879097634822, \"functional effect\": -2.5217, \"times_seen\": 13.0}, {\"site\": 987, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": null, \"functional effect\": -2.9304, \"times_seen\": null}, {\"site\": 987, \"mutant\": \"A\", \"log2 fold change IC90\": -0.031220963928858557, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08557192585352458, \"functional effect\": 0.3188, \"times_seen\": 8.0}, {\"site\": 987, \"mutant\": \"D\", \"log2 fold change IC90\": -0.04187429570294815, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08494236209407979, \"functional effect\": 0.3632, \"times_seen\": 20.0}, {\"site\": 987, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 987, \"mutant\": \"G\", \"log2 fold change IC90\": -0.15399817748512432, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.07859079502530279, \"functional effect\": -0.5187, \"times_seen\": 43.0}, {\"site\": 987, \"mutant\": \"K\", \"log2 fold change IC90\": -0.16331296574726611, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.07808500661992657, \"functional effect\": -1.9929, \"times_seen\": 37.0}, {\"site\": 987, \"mutant\": \"N\", \"log2 fold change IC90\": -0.04920544756810443, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08451181661846618, \"functional effect\": 0.4444, \"times_seen\": 14.0}, {\"site\": 987, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.35502179465675365, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.06836873486215185, \"functional effect\": 0.3215, \"times_seen\": 30.0}, {\"site\": 987, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0030877947123403313, \"epitope\": \"all\", \"reference_site\": \"990\", \"IC90\": 0.08763130347142857, \"functional effect\": -1.6432, \"times_seen\": 5.0}, {\"site\": 988, \"mutant\": \"A\", \"log2 fold change IC90\": -0.009655352616376109, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08686067541945791, \"functional effect\": -1.6111, \"times_seen\": 3.0}, {\"site\": 988, \"mutant\": \"C\", \"log2 fold change IC90\": -0.021222344493535602, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08616704321099157, \"functional effect\": -2.2801, \"times_seen\": 7.0}, {\"site\": 988, \"mutant\": \"D\", \"log2 fold change IC90\": -0.00022528004074917388, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.0874302935954157, \"functional effect\": -0.113, \"times_seen\": 2.0}, {\"site\": 988, \"mutant\": \"F\", \"log2 fold change IC90\": -0.10507013285535663, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08130186183776993, \"functional effect\": -0.6941, \"times_seen\": 22.0}, {\"site\": 988, \"mutant\": \"I\", \"log2 fold change IC90\": -0.07858134001634519, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.0828084036168204, \"functional effect\": -0.3699, \"times_seen\": 12.0}, {\"site\": 988, \"mutant\": \"L\", \"log2 fold change IC90\": -0.011841228627544505, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.08672916952441356, \"functional effect\": -1.7365, \"times_seen\": 2.0}, {\"site\": 988, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"991\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": null, \"functional effect\": -3.0082, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": null, \"functional effect\": -0.1337, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03566023135379252, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.08963230234880105, \"functional effect\": 0.4444, \"times_seen\": 10.0}, {\"site\": 989, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": null, \"functional effect\": -2.6481, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"L\", \"log2 fold change IC90\": -0.006968177657799918, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.08702261355312842, \"functional effect\": -2.8081, \"times_seen\": 1.0}, {\"site\": 989, \"mutant\": \"P\", \"log2 fold change IC90\": 0.02484650435597667, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.08896297464205606, \"functional effect\": -1.6191, \"times_seen\": 1.0}, {\"site\": 989, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 989, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0023471515182979163, \"epitope\": \"all\", \"reference_site\": \"992\", \"IC90\": 0.08730179832624287, \"functional effect\": -2.3991, \"times_seen\": 2.0}, {\"site\": 990, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 990, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010692005460099751, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.08679828383942688, \"functional effect\": -0.2947, \"times_seen\": 8.0}, {\"site\": 990, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": null, \"functional effect\": -0.9604, \"times_seen\": null}, {\"site\": 990, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005300936397877777, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.08712323880994362, \"functional effect\": -1.1686, \"times_seen\": 1.0}, {\"site\": 990, \"mutant\": \"T\", \"log2 fold change IC90\": 0.00012167036418681407, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.08745132203363247, \"functional effect\": 0.3956, \"times_seen\": 1.0}, {\"site\": 990, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03736552042630345, \"epitope\": \"all\", \"reference_site\": \"993\", \"IC90\": 0.08520824303063491, \"functional effect\": 0.2884, \"times_seen\": 22.0}, {\"site\": 991, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 991, \"mutant\": \"E\", \"log2 fold change IC90\": 0.027021959613934034, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08909722405413188, \"functional effect\": -2.5788, \"times_seen\": 4.0}, {\"site\": 991, \"mutant\": \"F\", \"log2 fold change IC90\": 0.02658630261860727, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08907032303366698, \"functional effect\": -2.2389, \"times_seen\": 9.0}, {\"site\": 991, \"mutant\": \"G\", \"log2 fold change IC90\": 0.15826576523683208, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.09758262474606806, \"functional effect\": -2.566, \"times_seen\": 8.0}, {\"site\": 991, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": null, \"functional effect\": -3.0081, \"times_seen\": null}, {\"site\": 991, \"mutant\": \"N\", \"log2 fold change IC90\": -0.021578208306188486, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08614579135241165, \"functional effect\": -2.6505, \"times_seen\": 5.0}, {\"site\": 991, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": null, \"functional effect\": -3.2113, \"times_seen\": null}, {\"site\": 991, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0028855738987418438, \"epitope\": \"all\", \"reference_site\": \"994\", \"IC90\": 0.08726922285428738, \"functional effect\": -2.8487, \"times_seen\": 1.0}, {\"site\": 992, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": null, \"functional effect\": -3.0002, \"times_seen\": null}, {\"site\": 992, \"mutant\": \"G\", \"log2 fold change IC90\": -0.005146022840035421, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08713259442229057, \"functional effect\": -2.973, \"times_seen\": 9.0}, {\"site\": 992, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0367756503406077, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08524308897436053, \"functional effect\": -2.282, \"times_seen\": 8.0}, {\"site\": 992, \"mutant\": \"I\", \"log2 fold change IC90\": -0.008143370201887195, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08695175541465379, \"functional effect\": -2.4317, \"times_seen\": 2.0}, {\"site\": 992, \"mutant\": \"K\", \"log2 fold change IC90\": -0.012127199187102242, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.08671197979929691, \"functional effect\": -2.8796, \"times_seen\": 20.0}, {\"site\": 992, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 992, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": null, \"functional effect\": -3.0258, \"times_seen\": null}, {\"site\": 992, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"995\", \"IC90\": null, \"functional effect\": -2.9769, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"M\", \"log2 fold change IC90\": 0.023282480149207908, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": 0.08886658223184213, \"functional effect\": -2.7368, \"times_seen\": 6.0}, {\"site\": 993, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.9947, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.71, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"R\", \"log2 fold change IC90\": -0.008236413404577992, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": 0.08694614784777493, \"functional effect\": -2.6411, \"times_seen\": 2.0}, {\"site\": 993, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.9676, \"times_seen\": null}, {\"site\": 993, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"996\", \"IC90\": null, \"functional effect\": -2.3938, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -1.7069, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -3.0751, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -2.0252, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": null, \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 994, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0038986519836570334, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": 0.08720796285100095, \"functional effect\": -2.9663, \"times_seen\": 1.0}, {\"site\": 994, \"mutant\": \"V\", \"log2 fold change IC90\": -0.010114509828934814, \"epitope\": \"all\", \"reference_site\": \"997\", \"IC90\": 0.08683303523317852, \"functional effect\": -0.4513, \"times_seen\": 6.0}, {\"site\": 995, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01794778208514204, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08636284330114896, \"functional effect\": -0.2182, \"times_seen\": 5.0}, {\"site\": 995, \"mutant\": \"G\", \"log2 fold change IC90\": 0.017500841840845008, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08851115972522872, \"functional effect\": -0.5475, \"times_seen\": 4.0}, {\"site\": 995, \"mutant\": \"I\", \"log2 fold change IC90\": 0.5510146281161605, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.12811550238277442, \"functional effect\": -0.1864, \"times_seen\": 58.0}, {\"site\": 995, \"mutant\": \"K\", \"log2 fold change IC90\": 0.00394031880661592, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08768310227380408, \"functional effect\": -2.9961, \"times_seen\": 5.0}, {\"site\": 995, \"mutant\": \"S\", \"log2 fold change IC90\": -0.03277348587674868, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.08547988919160723, \"functional effect\": 0.2187, \"times_seen\": 8.0}, {\"site\": 995, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"998\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"C\", \"log2 fold change IC90\": -0.006238471491212058, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08706664018234624, \"functional effect\": -2.0619, \"times_seen\": 16.0}, {\"site\": 996, \"mutant\": \"D\", \"log2 fold change IC90\": 0.039599171094553395, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08987735666397599, \"functional effect\": -2.9368, \"times_seen\": 14.0}, {\"site\": 996, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": null, \"functional effect\": -2.3833, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": null, \"functional effect\": -2.312, \"times_seen\": null}, {\"site\": 996, \"mutant\": \"S\", \"log2 fold change IC90\": 0.015348947517731899, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08837923670666485, \"functional effect\": -1.7115, \"times_seen\": 14.0}, {\"site\": 996, \"mutant\": \"V\", \"log2 fold change IC90\": -0.008418222245008287, \"epitope\": \"all\", \"reference_site\": \"999\", \"IC90\": 0.08693519155980266, \"functional effect\": -2.3977, \"times_seen\": 1.0}, {\"site\": 997, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0002885715210482918, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08746143960574837, \"functional effect\": -2.1814, \"times_seen\": 1.0}, {\"site\": 997, \"mutant\": \"H\", \"log2 fold change IC90\": -0.00780707942398812, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08697202614473645, \"functional effect\": -2.3084, \"times_seen\": 3.0}, {\"site\": 997, \"mutant\": \"I\", \"log2 fold change IC90\": -0.011840263364828445, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08672922755224298, \"functional effect\": -2.6788, \"times_seen\": 2.0}, {\"site\": 997, \"mutant\": \"K\", \"log2 fold change IC90\": 0.08267496918527098, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.0926013671209695, \"functional effect\": -2.9436, \"times_seen\": 3.0}, {\"site\": 997, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 997, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0015648302516487094, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": 0.08734915176729524, \"functional effect\": -2.8379, \"times_seen\": 1.0}, {\"site\": 997, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1000\", \"IC90\": null, \"functional effect\": -2.983, \"times_seen\": null}, {\"site\": 998, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": null, \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 998, \"mutant\": \"F\", \"log2 fold change IC90\": -0.001807219298653897, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08733447735687198, \"functional effect\": -2.4962, \"times_seen\": 7.0}, {\"site\": 998, \"mutant\": \"H\", \"log2 fold change IC90\": -0.001259929159761667, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.0873676142042648, \"functional effect\": -2.0806, \"times_seen\": 1.0}, {\"site\": 998, \"mutant\": \"I\", \"log2 fold change IC90\": 0.010629335231551944, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.0880905865139943, \"functional effect\": 0.0572, \"times_seen\": 4.0}, {\"site\": 998, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 998, \"mutant\": \"P\", \"log2 fold change IC90\": -0.06039809181054369, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08385869805698747, \"functional effect\": -2.5626, \"times_seen\": 3.0}, {\"site\": 998, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.8693339467674552, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.15974429133736817, \"functional effect\": -2.0474, \"times_seen\": 4.0}, {\"site\": 998, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01915855576533181, \"epitope\": \"all\", \"reference_site\": \"1001\", \"IC90\": 0.08629039417727177, \"functional effect\": -1.1479, \"times_seen\": 8.0}, {\"site\": 999, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": null, \"functional effect\": -1.1754, \"times_seen\": null}, {\"site\": 999, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": null, \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 999, \"mutant\": \"A\", \"log2 fold change IC90\": 0.017746646945012913, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08852624146305343, \"functional effect\": -1.4619, \"times_seen\": 2.0}, {\"site\": 999, \"mutant\": \"E\", \"log2 fold change IC90\": 0.016438781520257368, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08844602496338144, \"functional effect\": 0.3082, \"times_seen\": 11.0}, {\"site\": 999, \"mutant\": \"H\", \"log2 fold change IC90\": -0.013451347275653227, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.0866324294973924, \"functional effect\": -0.8236, \"times_seen\": 20.0}, {\"site\": 999, \"mutant\": \"K\", \"log2 fold change IC90\": -0.20288274240544343, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.07597242022070066, \"functional effect\": -2.6935, \"times_seen\": 14.0}, {\"site\": 999, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05724426969203955, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.08404221896748537, \"functional effect\": -2.3498, \"times_seen\": 12.0}, {\"site\": 999, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 999, \"mutant\": \"R\", \"log2 fold change IC90\": -0.007313133512488684, \"epitope\": \"all\", \"reference_site\": \"1002\", \"IC90\": 0.0870018084830156, \"functional effect\": -2.6958, \"times_seen\": 3.0}, {\"site\": 1000, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": null, \"functional effect\": -2.9351, \"times_seen\": null}, {\"site\": 1000, \"mutant\": \"D\", \"log2 fold change IC90\": 0.04938802824639367, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.09048925876725253, \"functional effect\": -2.9328, \"times_seen\": 2.0}, {\"site\": 1000, \"mutant\": \"F\", \"log2 fold change IC90\": -0.042314498438862244, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08491644798533998, \"functional effect\": -0.1891, \"times_seen\": 13.0}, {\"site\": 1000, \"mutant\": \"I\", \"log2 fold change IC90\": 0.4800964727117326, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.12197004721174666, \"functional effect\": 0.4444, \"times_seen\": 28.0}, {\"site\": 1000, \"mutant\": \"P\", \"log2 fold change IC90\": -0.001988785806325623, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08732348680251058, \"functional effect\": -1.803, \"times_seen\": 1.0}, {\"site\": 1000, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1000, \"mutant\": \"T\", \"log2 fold change IC90\": -0.014833635209152074, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08654946420782283, \"functional effect\": -0.0835, \"times_seen\": 20.0}, {\"site\": 1000, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.008709246779025992, \"epitope\": \"all\", \"reference_site\": \"1003\", \"IC90\": 0.08691765651514903, \"functional effect\": -0.1014, \"times_seen\": 2.0}, {\"site\": 1001, \"mutant\": \"F\", \"log2 fold change IC90\": -0.007657638075283844, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.08698103559558978, \"functional effect\": -2.8704, \"times_seen\": 3.0}, {\"site\": 1001, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": null, \"functional effect\": -2.086, \"times_seen\": null}, {\"site\": 1001, \"mutant\": \"I\", \"log2 fold change IC90\": -0.007019694699609908, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.08701950612747669, \"functional effect\": -2.6321, \"times_seen\": 8.0}, {\"site\": 1001, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1001, \"mutant\": \"P\", \"log2 fold change IC90\": -0.12806163963341952, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": 0.08001646444210037, \"functional effect\": -2.6499, \"times_seen\": 2.0}, {\"site\": 1001, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1004\", \"IC90\": null, \"functional effect\": -3.137, \"times_seen\": null}, {\"site\": 1002, \"mutant\": \"*\", \"log2 fold change IC90\": -0.004914431737236622, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.0871465826545862, \"functional effect\": -2.2327, \"times_seen\": 1.0}, {\"site\": 1002, \"mutant\": \"H\", \"log2 fold change IC90\": -0.009172157756824912, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08688977211693383, \"functional effect\": -0.8476, \"times_seen\": 62.0}, {\"site\": 1002, \"mutant\": \"K\", \"log2 fold change IC90\": -0.022841102328122146, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08607041478385168, \"functional effect\": -2.1267, \"times_seen\": 11.0}, {\"site\": 1002, \"mutant\": \"L\", \"log2 fold change IC90\": 0.004841274129703471, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08773787700285102, \"functional effect\": -1.2242, \"times_seen\": 20.0}, {\"site\": 1002, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1002, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0002210271944566798, \"epitope\": \"all\", \"reference_site\": \"1005\", \"IC90\": 0.08743055132704815, \"functional effect\": -2.6955, \"times_seen\": 15.0}, {\"site\": 1003, \"mutant\": \"A\", \"log2 fold change IC90\": -0.055433452952989334, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08414777183974108, \"functional effect\": -0.0438, \"times_seen\": 21.0}, {\"site\": 1003, \"mutant\": \"I\", \"log2 fold change IC90\": -1.794532236521266, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.025207032506569204, \"functional effect\": -1.2634, \"times_seen\": 46.0}, {\"site\": 1003, \"mutant\": \"L\", \"log2 fold change IC90\": -0.029453079355628294, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08567685032582374, \"functional effect\": -2.1087, \"times_seen\": 5.0}, {\"site\": 1003, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02285569937638282, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08606954393616252, \"functional effect\": 0.2832, \"times_seen\": 3.0}, {\"site\": 1003, \"mutant\": \"S\", \"log2 fold change IC90\": 0.004124865202706001, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08769431922199174, \"functional effect\": 0.1799, \"times_seen\": 29.0}, {\"site\": 1003, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1003, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03808762619316541, \"epitope\": \"all\", \"reference_site\": \"1006\", \"IC90\": 0.08516560479733415, \"functional effect\": -0.6323, \"times_seen\": 11.0}, {\"site\": 1004, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": null, \"functional effect\": -3.0158, \"times_seen\": null}, {\"site\": 1004, \"mutant\": \"C\", \"log2 fold change IC90\": 0.015282684001597357, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.0883751775088981, \"functional effect\": -2.9151, \"times_seen\": 4.0}, {\"site\": 1004, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": null, \"functional effect\": 1.2037, \"times_seen\": null}, {\"site\": 1004, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": null, \"functional effect\": 0.4014, \"times_seen\": null}, {\"site\": 1004, \"mutant\": \"H\", \"log2 fold change IC90\": -0.011443317685888776, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.08675309366926534, \"functional effect\": -2.7839, \"times_seen\": 4.0}, {\"site\": 1004, \"mutant\": \"N\", \"log2 fold change IC90\": -0.005030242120673399, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.0871395873618894, \"functional effect\": -2.6162, \"times_seen\": 1.0}, {\"site\": 1004, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005374748545756069, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.0871187814653906, \"functional effect\": -1.62, \"times_seen\": 1.0}, {\"site\": 1004, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1007\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1005, \"mutant\": \"A\", \"log2 fold change IC90\": 0.014625763429114362, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.08833494568235314, \"functional effect\": -1.0404, \"times_seen\": 11.0}, {\"site\": 1005, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": null, \"functional effect\": -3.1121, \"times_seen\": null}, {\"site\": 1005, \"mutant\": \"L\", \"log2 fold change IC90\": 0.6308154966024759, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.13540170685235678, \"functional effect\": -1.0029, \"times_seen\": 11.0}, {\"site\": 1005, \"mutant\": \"M\", \"log2 fold change IC90\": -0.014924731012197549, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.08654399940493047, \"functional effect\": -1.1313, \"times_seen\": 6.0}, {\"site\": 1005, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0015491232076198273, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.08753789224564378, \"functional effect\": -2.9835, \"times_seen\": 1.0}, {\"site\": 1005, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1008\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1006, \"mutant\": \"A\", \"log2 fold change IC90\": -0.06261894200221764, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08372970729383246, \"functional effect\": -2.336, \"times_seen\": 6.0}, {\"site\": 1006, \"mutant\": \"H\", \"log2 fold change IC90\": 0.02248386306969222, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08881740293279987, \"functional effect\": -1.0774, \"times_seen\": 19.0}, {\"site\": 1006, \"mutant\": \"I\", \"log2 fold change IC90\": 0.00911818854837242, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08799836459510552, \"functional effect\": -0.1907, \"times_seen\": 75.0}, {\"site\": 1006, \"mutant\": \"K\", \"log2 fold change IC90\": -0.007086600263424652, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.08701547065639198, \"functional effect\": -3.0194, \"times_seen\": 1.0}, {\"site\": 1006, \"mutant\": \"N\", \"log2 fold change IC90\": -0.9600533429492891, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.04494950351672237, \"functional effect\": -1.5244, \"times_seen\": 21.0}, {\"site\": 1006, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": null, \"functional effect\": -2.8706, \"times_seen\": null}, {\"site\": 1006, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04410001743121082, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.09015818928878053, \"functional effect\": -2.2375, \"times_seen\": 7.0}, {\"site\": 1006, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1006, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1009\", \"IC90\": null, \"functional effect\": -3.2055, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": -2.956, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": -0.9976, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03301843473436116, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.08546537716847628, \"functional effect\": -0.0605, \"times_seen\": 26.0}, {\"site\": 1007, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01766931457354408, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.0863795145771405, \"functional effect\": -0.3591, \"times_seen\": 8.0}, {\"site\": 1007, \"mutant\": \"M\", \"log2 fold change IC90\": 0.06668236898604227, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.09158052862891139, \"functional effect\": -0.2318, \"times_seen\": 19.0}, {\"site\": 1007, \"mutant\": \"N\", \"log2 fold change IC90\": -0.008699217021935775, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.08691826077730236, \"functional effect\": -0.1312, \"times_seen\": 38.0}, {\"site\": 1007, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1007, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1010\", \"IC90\": null, \"functional effect\": 0.0937, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": null, \"functional effect\": -2.674, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": null, \"functional effect\": -1.6132, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"H\", \"log2 fold change IC90\": -0.24889774845007526, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.07358750268849026, \"functional effect\": -0.0277, \"times_seen\": 29.0}, {\"site\": 1008, \"mutant\": \"K\", \"log2 fold change IC90\": -0.06507424090657056, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.08358733027435829, \"functional effect\": -1.6652, \"times_seen\": 15.0}, {\"site\": 1008, \"mutant\": \"L\", \"log2 fold change IC90\": -0.022157386849166197, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.08611121455082532, \"functional effect\": -0.8592, \"times_seen\": 25.0}, {\"site\": 1008, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1008, \"mutant\": \"R\", \"log2 fold change IC90\": -0.018268859975160527, \"epitope\": \"all\", \"reference_site\": \"1011\", \"IC90\": 0.08634362502332806, \"functional effect\": -0.8773, \"times_seen\": 4.0}, {\"site\": 1009, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1009, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04115021843187492, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.08498500469627784, \"functional effect\": -0.9178, \"times_seen\": 13.0}, {\"site\": 1009, \"mutant\": \"H\", \"log2 fold change IC90\": -0.007927595052933377, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.08696476123402373, \"functional effect\": -0.3205, \"times_seen\": 2.0}, {\"site\": 1009, \"mutant\": \"I\", \"log2 fold change IC90\": 0.17514110835240854, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.09873075995795903, \"functional effect\": -2.4375, \"times_seen\": 5.0}, {\"site\": 1009, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1009, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": null, \"functional effect\": -2.955, \"times_seen\": null}, {\"site\": 1009, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00796404509658822, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.0869625640757816, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1009, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02499335489581761, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": 0.08594210827579647, \"functional effect\": 0.0151, \"times_seen\": 3.0}, {\"site\": 1009, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1012\", \"IC90\": null, \"functional effect\": -2.4856, \"times_seen\": null}, {\"site\": 1010, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": null, \"functional effect\": -0.599, \"times_seen\": null}, {\"site\": 1010, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1010, \"mutant\": \"L\", \"log2 fold change IC90\": -0.016821431294281874, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08643029542133142, \"functional effect\": -0.6953, \"times_seen\": 7.0}, {\"site\": 1010, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0003401301427687543, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08742333371950435, \"functional effect\": -0.9232, \"times_seen\": 2.0}, {\"site\": 1010, \"mutant\": \"N\", \"log2 fold change IC90\": 0.05393700774387289, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.09077503186384414, \"functional effect\": -2.0467, \"times_seen\": 12.0}, {\"site\": 1010, \"mutant\": \"S\", \"log2 fold change IC90\": 1.8054241297636417, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.30564448987115045, \"functional effect\": -1.7187, \"times_seen\": 17.0}, {\"site\": 1010, \"mutant\": \"T\", \"log2 fold change IC90\": 0.004339461859785567, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08770736446503656, \"functional effect\": -1.9471, \"times_seen\": 1.0}, {\"site\": 1010, \"mutant\": \"V\", \"log2 fold change IC90\": -0.06298367801011687, \"epitope\": \"all\", \"reference_site\": \"1013\", \"IC90\": 0.08370854178189772, \"functional effect\": -2.111, \"times_seen\": 4.0}, {\"site\": 1011, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1011, \"mutant\": \"G\", \"log2 fold change IC90\": -0.15694261037776705, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.07843056064766142, \"functional effect\": -1.1865, \"times_seen\": 41.0}, {\"site\": 1011, \"mutant\": \"I\", \"log2 fold change IC90\": -0.009493722771975507, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.0868704072501755, \"functional effect\": -0.8212, \"times_seen\": 18.0}, {\"site\": 1011, \"mutant\": \"K\", \"log2 fold change IC90\": -0.019321800817623067, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08628063072582993, \"functional effect\": 0.4444, \"times_seen\": 71.0}, {\"site\": 1011, \"mutant\": \"M\", \"log2 fold change IC90\": 0.009406140316919213, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08801593020179006, \"functional effect\": -0.7817, \"times_seen\": 13.0}, {\"site\": 1011, \"mutant\": \"N\", \"log2 fold change IC90\": -0.015073030930770356, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08653510368679702, \"functional effect\": -0.9301, \"times_seen\": 7.0}, {\"site\": 1011, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1011, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0010557122059996703, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08750795884134677, \"functional effect\": -0.6521, \"times_seen\": 19.0}, {\"site\": 1011, \"mutant\": \"T\", \"log2 fold change IC90\": -0.1100833381549803, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08101983716872595, \"functional effect\": -0.1905, \"times_seen\": 38.0}, {\"site\": 1011, \"mutant\": \"W\", \"log2 fold change IC90\": -0.008971883280484401, \"epitope\": \"all\", \"reference_site\": \"1014\", \"IC90\": 0.08690183496530386, \"functional effect\": -0.8081, \"times_seen\": 3.0}, {\"site\": 1012, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1012, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1012, \"mutant\": \"D\", \"log2 fold change IC90\": 0.03088173083531088, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08933591298594651, \"functional effect\": -3.0886, \"times_seen\": 2.0}, {\"site\": 1012, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": null, \"functional effect\": -0.4353, \"times_seen\": null}, {\"site\": 1012, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.023403161112505795, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08603688918832075, \"functional effect\": -2.2673, \"times_seen\": 5.0}, {\"site\": 1012, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02221322833009693, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08880074326487274, \"functional effect\": -0.2662, \"times_seen\": 34.0}, {\"site\": 1012, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0015358692649941775, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08735090525153005, \"functional effect\": -2.0108, \"times_seen\": 7.0}, {\"site\": 1012, \"mutant\": \"V\", \"log2 fold change IC90\": -0.021565166399838954, \"epitope\": \"all\", \"reference_site\": \"1015\", \"IC90\": 0.08614657011049262, \"functional effect\": -2.7786, \"times_seen\": 5.0}, {\"site\": 1013, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": null, \"functional effect\": -3.0364, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0039593180361646805, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.08768425700318894, \"functional effect\": -1.9172, \"times_seen\": 1.0}, {\"site\": 1013, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": null, \"functional effect\": 0.2801, \"times_seen\": null}, {\"site\": 1013, \"mutant\": \"L\", \"log2 fold change IC90\": 0.016648412799029993, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.08845887757596559, \"functional effect\": -0.5694, \"times_seen\": 4.0}, {\"site\": 1013, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02334744643069186, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.08887058409032512, \"functional effect\": -0.1187, \"times_seen\": 11.0}, {\"site\": 1013, \"mutant\": \"S\", \"log2 fold change IC90\": -0.1585753979020728, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.07834184612541084, \"functional effect\": 0.1466, \"times_seen\": 56.0}, {\"site\": 1013, \"mutant\": \"T\", \"log2 fold change IC90\": 0.1682239473710818, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.09825851742080527, \"functional effect\": 0.4444, \"times_seen\": 145.0}, {\"site\": 1013, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04334151018889846, \"epitope\": \"all\", \"reference_site\": \"1016\", \"IC90\": 0.09011080043415633, \"functional effect\": 0.3904, \"times_seen\": 64.0}, {\"site\": 1014, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": null, \"functional effect\": -0.7502, \"times_seen\": null}, {\"site\": 1014, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1014, \"mutant\": \"D\", \"log2 fold change IC90\": -0.2536020865978444, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.07334793944967691, \"functional effect\": -0.3865, \"times_seen\": 15.0}, {\"site\": 1014, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1014, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04191235363794996, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.08494012136532915, \"functional effect\": 0.2148, \"times_seen\": 5.0}, {\"site\": 1014, \"mutant\": \"K\", \"log2 fold change IC90\": -0.21469440498606118, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.07535295655874058, \"functional effect\": 0.3651, \"times_seen\": 40.0}, {\"site\": 1014, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.007313767146312748, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.08788837123541998, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1014, \"mutant\": \"V\", \"log2 fold change IC90\": -0.007024647477689131, \"epitope\": \"all\", \"reference_site\": \"1017\", \"IC90\": 0.0870192073896628, \"functional effect\": -0.3501, \"times_seen\": 1.0}, {\"site\": 1015, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": null, \"functional effect\": -0.7277, \"times_seen\": null}, {\"site\": 1015, \"mutant\": \"F\", \"log2 fold change IC90\": -0.064855918315237, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08359998047617398, \"functional effect\": -1.9964, \"times_seen\": 16.0}, {\"site\": 1015, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1015, \"mutant\": \"L\", \"log2 fold change IC90\": -0.09463651449476204, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08189197086974946, \"functional effect\": -1.319, \"times_seen\": 22.0}, {\"site\": 1015, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0836609863194516, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08251735267556938, \"functional effect\": -0.0369, \"times_seen\": 50.0}, {\"site\": 1015, \"mutant\": \"S\", \"log2 fold change IC90\": -0.009016773700765755, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.08689913099870465, \"functional effect\": -2.6882, \"times_seen\": 2.0}, {\"site\": 1015, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004318441044774107, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.0871825911527759, \"functional effect\": -1.1885, \"times_seen\": 1.0}, {\"site\": 1015, \"mutant\": \"V\", \"log2 fold change IC90\": 0.3914664235421299, \"epitope\": \"all\", \"reference_site\": \"1018\", \"IC90\": 0.1147025013018334, \"functional effect\": -0.4457, \"times_seen\": 81.0}, {\"site\": 1016, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01492967619959928, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08654370275487629, \"functional effect\": -2.4929, \"times_seen\": 1.0}, {\"site\": 1016, \"mutant\": \"G\", \"log2 fold change IC90\": -2.4877137529188014, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.015590257650721126, \"functional effect\": -1.5594, \"times_seen\": 21.0}, {\"site\": 1016, \"mutant\": \"K\", \"log2 fold change IC90\": -0.010080146244042288, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.0868351035357859, \"functional effect\": -0.6401, \"times_seen\": 29.0}, {\"site\": 1016, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01852357791910284, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08632838179548279, \"functional effect\": -2.7786, \"times_seen\": 3.0}, {\"site\": 1016, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02906485664996574, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08569990868077128, \"functional effect\": -1.9902, \"times_seen\": 4.0}, {\"site\": 1016, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1016, \"mutant\": \"S\", \"log2 fold change IC90\": -0.034266997700128615, \"epitope\": \"all\", \"reference_site\": \"1019\", \"IC90\": 0.08539144418879777, \"functional effect\": -1.9743, \"times_seen\": 1.0}, {\"site\": 1017, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006384074120376288, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08705785350763569, \"functional effect\": -2.9948, \"times_seen\": 1.0}, {\"site\": 1017, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1017, \"mutant\": \"C\", \"log2 fold change IC90\": 0.011242973408423229, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.0881280630721607, \"functional effect\": -0.6982, \"times_seen\": 17.0}, {\"site\": 1017, \"mutant\": \"D\", \"log2 fold change IC90\": 0.07725346011005359, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.09225403313067314, \"functional effect\": -0.958, \"times_seen\": 28.0}, {\"site\": 1017, \"mutant\": \"E\", \"log2 fold change IC90\": 0.03062841853832648, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08932022852174003, \"functional effect\": -1.0272, \"times_seen\": 40.0}, {\"site\": 1017, \"mutant\": \"F\", \"log2 fold change IC90\": -0.25639267834608115, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.07320620033155467, \"functional effect\": -0.2906, \"times_seen\": 12.0}, {\"site\": 1017, \"mutant\": \"G\", \"log2 fold change IC90\": -0.11927116298357236, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08050550064877193, \"functional effect\": -0.8455, \"times_seen\": 81.0}, {\"site\": 1017, \"mutant\": \"H\", \"log2 fold change IC90\": -0.04028521754604814, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08503597468272611, \"functional effect\": -1.6341, \"times_seen\": 13.0}, {\"site\": 1017, \"mutant\": \"I\", \"log2 fold change IC90\": -0.017396101111383882, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08639587443169335, \"functional effect\": -0.6665, \"times_seen\": 6.0}, {\"site\": 1017, \"mutant\": \"K\", \"log2 fold change IC90\": -2.660672186424779, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.01382889936089391, \"functional effect\": -1.8672, \"times_seen\": 18.0}, {\"site\": 1017, \"mutant\": \"L\", \"log2 fold change IC90\": -0.05353818972839469, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08425838910419534, \"functional effect\": -2.4464, \"times_seen\": 14.0}, {\"site\": 1017, \"mutant\": \"M\", \"log2 fold change IC90\": -0.027698957707627144, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08578108511928674, \"functional effect\": -0.9902, \"times_seen\": 15.0}, {\"site\": 1017, \"mutant\": \"N\", \"log2 fold change IC90\": -0.038570332916141634, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08513711427635044, \"functional effect\": -0.6127, \"times_seen\": 11.0}, {\"site\": 1017, \"mutant\": \"P\", \"log2 fold change IC90\": 0.007407049013527768, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.0878940541110068, \"functional effect\": -2.7603, \"times_seen\": 5.0}, {\"site\": 1017, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.7028954653052351, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.14233849570309465, \"functional effect\": -0.7244, \"times_seen\": 22.0}, {\"site\": 1017, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08861654390044553, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08223439752607112, \"functional effect\": -0.4314, \"times_seen\": 74.0}, {\"site\": 1017, \"mutant\": \"S\", \"log2 fold change IC90\": -0.5409503968258863, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.0601017969898834, \"functional effect\": -0.2797, \"times_seen\": 111.0}, {\"site\": 1017, \"mutant\": \"T\", \"log2 fold change IC90\": -0.352411096170806, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.06849256681743328, \"functional effect\": -0.3397, \"times_seen\": 101.0}, {\"site\": 1017, \"mutant\": \"V\", \"log2 fold change IC90\": -0.28618149634852796, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.07171013469000628, \"functional effect\": -0.6024, \"times_seen\": 127.0}, {\"site\": 1017, \"mutant\": \"W\", \"log2 fold change IC90\": -0.007212903109969895, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08700785309324875, \"functional effect\": -0.2591, \"times_seen\": 19.0}, {\"site\": 1017, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04535646758629471, \"epitope\": \"all\", \"reference_site\": \"1020\", \"IC90\": 0.08473758754152518, \"functional effect\": -0.4778, \"times_seen\": 10.0}, {\"site\": 1018, \"mutant\": \"A\", \"log2 fold change IC90\": -0.007597159967188353, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.08698468193704453, \"functional effect\": -0.9083, \"times_seen\": 1.0}, {\"site\": 1018, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04484448691502443, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.08476766438011278, \"functional effect\": -0.8606, \"times_seen\": 10.0}, {\"site\": 1018, \"mutant\": \"F\", \"log2 fold change IC90\": -0.2228990282208555, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.07492563966078024, \"functional effect\": -0.9573, \"times_seen\": 27.0}, {\"site\": 1018, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014047578433768209, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.08659663379538024, \"functional effect\": -0.9223, \"times_seen\": 7.0}, {\"site\": 1018, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": null, \"functional effect\": -1.9687, \"times_seen\": null}, {\"site\": 1018, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1018, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": null, \"functional effect\": -1.5061, \"times_seen\": null}, {\"site\": 1018, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06731969331564702, \"epitope\": \"all\", \"reference_site\": \"1021\", \"IC90\": 0.08345733372039539, \"functional effect\": -0.5607, \"times_seen\": 20.0}, {\"site\": 1019, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"D\", \"log2 fold change IC90\": 0.026959121074011203, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.0890933433881675, \"functional effect\": -2.8753, \"times_seen\": 1.0}, {\"site\": 1019, \"mutant\": \"E\", \"log2 fold change IC90\": -0.02182001752145624, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08613135372007068, \"functional effect\": -2.4657, \"times_seen\": 6.0}, {\"site\": 1019, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": null, \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"L\", \"log2 fold change IC90\": 0.012835701677381676, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08822540974800014, \"functional effect\": -2.9181, \"times_seen\": 1.0}, {\"site\": 1019, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": null, \"functional effect\": -1.672, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": null, \"functional effect\": -2.958, \"times_seen\": null}, {\"site\": 1019, \"mutant\": \"S\", \"log2 fold change IC90\": -0.023193489866186707, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08604939409906251, \"functional effect\": -0.8362, \"times_seen\": 34.0}, {\"site\": 1019, \"mutant\": \"T\", \"log2 fold change IC90\": -0.01172344098061997, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.08673625074500622, \"functional effect\": -2.3735, \"times_seen\": 9.0}, {\"site\": 1019, \"mutant\": \"V\", \"log2 fold change IC90\": 0.031902384595062075, \"epitope\": \"all\", \"reference_site\": \"1022\", \"IC90\": 0.0893991372253798, \"functional effect\": -2.7325, \"times_seen\": 2.0}, {\"site\": 1020, \"mutant\": \"D\", \"log2 fold change IC90\": 0.04153795674832582, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.08999822078517067, \"functional effect\": -1.4309, \"times_seen\": 27.0}, {\"site\": 1020, \"mutant\": \"H\", \"log2 fold change IC90\": -0.02452078091635702, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.08597026436943737, \"functional effect\": 0.1589, \"times_seen\": 29.0}, {\"site\": 1020, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0006448231378207262, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.08748303954595059, \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1020, \"mutant\": \"K\", \"log2 fold change IC90\": 1.3288516974182338, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.21966151446480175, \"functional effect\": 0.0756, \"times_seen\": 79.0}, {\"site\": 1020, \"mutant\": \"L\", \"log2 fold change IC90\": -0.17826233401943456, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.07728005868220417, \"functional effect\": 0.4444, \"times_seen\": 16.0}, {\"site\": 1020, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1020, \"mutant\": \"S\", \"log2 fold change IC90\": 0.18273632735609818, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.09925190899289162, \"functional effect\": -0.5625, \"times_seen\": 83.0}, {\"site\": 1020, \"mutant\": \"T\", \"log2 fold change IC90\": -0.1883102891264015, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.07674369532545382, \"functional effect\": 0.031, \"times_seen\": 63.0}, {\"site\": 1020, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.48005647098695553, \"epitope\": \"all\", \"reference_site\": \"1023\", \"IC90\": 0.0626928994052482, \"functional effect\": 0.3044, \"times_seen\": 54.0}, {\"site\": 1021, \"mutant\": \"F\", \"log2 fold change IC90\": -0.023343141914944406, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08604046858127547, \"functional effect\": -2.1134, \"times_seen\": 8.0}, {\"site\": 1021, \"mutant\": \"I\", \"log2 fold change IC90\": -0.018865658301630003, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08630791472226204, \"functional effect\": -1.4723, \"times_seen\": 25.0}, {\"site\": 1021, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1021, \"mutant\": \"M\", \"log2 fold change IC90\": 0.016026926891060722, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08842077936068897, \"functional effect\": -1.4396, \"times_seen\": 23.0}, {\"site\": 1021, \"mutant\": \"P\", \"log2 fold change IC90\": -0.015097297884165754, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08653364812924141, \"functional effect\": -2.4232, \"times_seen\": 1.0}, {\"site\": 1021, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.001328785305821189, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08752452390226917, \"functional effect\": -1.5057, \"times_seen\": 1.0}, {\"site\": 1021, \"mutant\": \"R\", \"log2 fold change IC90\": -0.10848415633278308, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08110969488869156, \"functional effect\": -0.5949, \"times_seen\": 24.0}, {\"site\": 1021, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0036429515622402936, \"epitope\": \"all\", \"reference_site\": \"1024\", \"IC90\": 0.08722342078802989, \"functional effect\": -2.3092, \"times_seen\": 1.0}, {\"site\": 1022, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": -2.2784, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0217834634793701, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.086133536086355, \"functional effect\": -0.9721, \"times_seen\": 11.0}, {\"site\": 1022, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02532081336786721, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.08899222744771196, \"functional effect\": -2.9406, \"times_seen\": 1.0}, {\"site\": 1022, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": -3.0015, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": -0.7165, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1022, \"mutant\": \"T\", \"log2 fold change IC90\": -0.009896625498170985, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.08684615026163384, \"functional effect\": -2.8946, \"times_seen\": 2.0}, {\"site\": 1022, \"mutant\": \"V\", \"log2 fold change IC90\": 0.009971832112005996, \"epitope\": \"all\", \"reference_site\": \"1025\", \"IC90\": 0.08805044869039334, \"functional effect\": -2.7023, \"times_seen\": 8.0}, {\"site\": 1023, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": null, \"functional effect\": -2.5221, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"G\", \"log2 fold change IC90\": -0.010373280692727277, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08681746171011995, \"functional effect\": -0.3951, \"times_seen\": 1.0}, {\"site\": 1023, \"mutant\": \"I\", \"log2 fold change IC90\": -0.013322287543315813, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08664017975504312, \"functional effect\": -2.9787, \"times_seen\": 2.0}, {\"site\": 1023, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": null, \"functional effect\": -2.8854, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1023, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01737179618761117, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08639732994569378, \"functional effect\": -0.2546, \"times_seen\": 19.0}, {\"site\": 1023, \"mutant\": \"T\", \"log2 fold change IC90\": 0.013970915763722204, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.08829485903548945, \"functional effect\": -1.8377, \"times_seen\": 25.0}, {\"site\": 1023, \"mutant\": \"V\", \"log2 fold change IC90\": -0.7108109925061848, \"epitope\": \"all\", \"reference_site\": \"1026\", \"IC90\": 0.0534262045818716, \"functional effect\": -2.9637, \"times_seen\": 6.0}, {\"site\": 1024, \"mutant\": \"*\", \"log2 fold change IC90\": -0.023051068246102417, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08605788924093483, \"functional effect\": -2.9022, \"times_seen\": 5.0}, {\"site\": 1024, \"mutant\": \"A\", \"log2 fold change IC90\": -0.09585528513550584, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08182281877538669, \"functional effect\": -1.9119, \"times_seen\": 85.0}, {\"site\": 1024, \"mutant\": \"C\", \"log2 fold change IC90\": -0.06551279766868702, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.0835619248929387, \"functional effect\": -0.6409, \"times_seen\": 34.0}, {\"site\": 1024, \"mutant\": \"D\", \"log2 fold change IC90\": -0.12108931393712101, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08040410780030965, \"functional effect\": -1.5114, \"times_seen\": 35.0}, {\"site\": 1024, \"mutant\": \"E\", \"log2 fold change IC90\": -0.05180732250104593, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08435953841205382, \"functional effect\": -1.0087, \"times_seen\": 33.0}, {\"site\": 1024, \"mutant\": \"F\", \"log2 fold change IC90\": 0.7109388893440455, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.14313428852215587, \"functional effect\": -0.8598, \"times_seen\": 48.0}, {\"site\": 1024, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0869741924299382, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08232806575348921, \"functional effect\": -1.9465, \"times_seen\": 35.0}, {\"site\": 1024, \"mutant\": \"H\", \"log2 fold change IC90\": -0.15195025660366965, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.07870243470883398, \"functional effect\": -0.8568, \"times_seen\": 38.0}, {\"site\": 1024, \"mutant\": \"I\", \"log2 fold change IC90\": 1.1347015058866132, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.19200341014795183, \"functional effect\": -2.4041, \"times_seen\": 54.0}, {\"site\": 1024, \"mutant\": \"K\", \"log2 fold change IC90\": -0.012245602650505153, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08670486355009958, \"functional effect\": -2.8558, \"times_seen\": 10.0}, {\"site\": 1024, \"mutant\": \"L\", \"log2 fold change IC90\": -0.2138567114542169, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.0753967225744301, \"functional effect\": 0.0517, \"times_seen\": 144.0}, {\"site\": 1024, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03125641564069311, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08556982309868227, \"functional effect\": 0.425, \"times_seen\": 43.0}, {\"site\": 1024, \"mutant\": \"N\", \"log2 fold change IC90\": -0.36696912581471, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.06780489354785749, \"functional effect\": -1.7085, \"times_seen\": 58.0}, {\"site\": 1024, \"mutant\": \"P\", \"log2 fold change IC90\": 0.004503221466601515, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08771732065002898, \"functional effect\": -2.5785, \"times_seen\": 10.0}, {\"site\": 1024, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.011792945034685108, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.0867320721932846, \"functional effect\": 0.4444, \"times_seen\": 35.0}, {\"site\": 1024, \"mutant\": \"R\", \"log2 fold change IC90\": 0.06249164049892234, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.09131489227130747, \"functional effect\": -0.8558, \"times_seen\": 117.0}, {\"site\": 1024, \"mutant\": \"S\", \"log2 fold change IC90\": -2.116798436137382, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.020160900616695666, \"functional effect\": -0.8175, \"times_seen\": 180.0}, {\"site\": 1024, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1024, \"mutant\": \"V\", \"log2 fold change IC90\": -0.028080605762010512, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08575839574042192, \"functional effect\": -2.3363, \"times_seen\": 33.0}, {\"site\": 1024, \"mutant\": \"W\", \"log2 fold change IC90\": 0.01043369589976201, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.08807864163685543, \"functional effect\": -2.0872, \"times_seen\": 8.0}, {\"site\": 1024, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0037057309046129943, \"epitope\": \"all\", \"reference_site\": \"1027\", \"IC90\": 0.0876688458147612, \"functional effect\": -2.6245, \"times_seen\": 12.0}, {\"site\": 1025, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01886786097969178, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.08630778294915697, \"functional effect\": -0.1676, \"times_seen\": 1.0}, {\"site\": 1025, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1025, \"mutant\": \"L\", \"log2 fold change IC90\": -1.1057611115912511, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.04063146581881779, \"functional effect\": -2.9637, \"times_seen\": 4.0}, {\"site\": 1025, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": null, \"functional effect\": -1.3488, \"times_seen\": null}, {\"site\": 1025, \"mutant\": \"N\", \"log2 fold change IC90\": -0.029472388237121748, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.08567570364337722, \"functional effect\": -2.6429, \"times_seen\": 4.0}, {\"site\": 1025, \"mutant\": \"R\", \"log2 fold change IC90\": -0.034054461179024685, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": 0.08540402490534808, \"functional effect\": -2.3767, \"times_seen\": 6.0}, {\"site\": 1025, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1028\", \"IC90\": null, \"functional effect\": -1.1122, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"C\", \"log2 fold change IC90\": -0.013388036362532099, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08663623133936876, \"functional effect\": -2.451, \"times_seen\": 1.0}, {\"site\": 1026, \"mutant\": \"I\", \"log2 fold change IC90\": -1.569158382910421, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.02946904158514, \"functional effect\": -1.349, \"times_seen\": 47.0}, {\"site\": 1026, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": null, \"functional effect\": -3.1075, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"L\", \"log2 fold change IC90\": -0.000869671079402128, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08739125089007459, \"functional effect\": -2.596, \"times_seen\": 2.0}, {\"site\": 1026, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1026, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011629270342532685, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08674191256155926, \"functional effect\": -2.2197, \"times_seen\": 1.0}, {\"site\": 1026, \"mutant\": \"T\", \"log2 fold change IC90\": -0.013295943003940821, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08664176187489685, \"functional effect\": -2.5108, \"times_seen\": 1.0}, {\"site\": 1026, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03881358825939378, \"epitope\": \"all\", \"reference_site\": \"1029\", \"IC90\": 0.08982842956103747, \"functional effect\": -1.3142, \"times_seen\": 25.0}, {\"site\": 1027, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0019517427047782312, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.08756232525437624, \"functional effect\": -0.1609, \"times_seen\": 17.0}, {\"site\": 1027, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -2.028, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"G\", \"log2 fold change IC90\": 0.04308279587415477, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.0900946425746452, \"functional effect\": -2.5245, \"times_seen\": 4.0}, {\"site\": 1027, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -3.1432, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"L\", \"log2 fold change IC90\": 0.06867727385393267, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.09170725035939, \"functional effect\": -2.9561, \"times_seen\": 3.0}, {\"site\": 1027, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0008883530158785275, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.08749780810866926, \"functional effect\": -2.4774, \"times_seen\": 1.0}, {\"site\": 1027, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0021777290788894572, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.08731205118754296, \"functional effect\": -2.6183, \"times_seen\": 1.0}, {\"site\": 1027, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": null, \"functional effect\": -1.0065, \"times_seen\": null}, {\"site\": 1027, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1030\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"*\", \"log2 fold change IC90\": 0.019059529937261514, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.0886068388817418, \"functional effect\": -2.7814, \"times_seen\": 1.0}, {\"site\": 1028, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -2.9215, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -3.0479, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"K\", \"log2 fold change IC90\": 1.115343474848194, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.18944432244992127, \"functional effect\": -2.9297, \"times_seen\": 11.0}, {\"site\": 1028, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -2.9998, \"times_seen\": null}, {\"site\": 1028, \"mutant\": \"S\", \"log2 fold change IC90\": 0.020061956689528305, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": 0.08866842690164567, \"functional effect\": -2.8256, \"times_seen\": 1.0}, {\"site\": 1028, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1031\", \"IC90\": null, \"functional effect\": -2.9863, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.7992, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.9457, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -3.2569, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -3.0016, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.9535, \"times_seen\": null}, {\"site\": 1029, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04322103924155864, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": 0.09010327612725175, \"functional effect\": -2.9152, \"times_seen\": 1.0}, {\"site\": 1029, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1032\", \"IC90\": null, \"functional effect\": -2.9672, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"A\", \"log2 fold change IC90\": 0.022885954642512946, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08884216056030413, \"functional effect\": -1.4429, \"times_seen\": 9.0}, {\"site\": 1030, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": null, \"functional effect\": -2.6421, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"L\", \"log2 fold change IC90\": -0.007947738394354812, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08696354701438738, \"functional effect\": -2.6888, \"times_seen\": 1.0}, {\"site\": 1030, \"mutant\": \"M\", \"log2 fold change IC90\": -0.009770766771367841, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08685372693056102, \"functional effect\": -2.434, \"times_seen\": 2.0}, {\"site\": 1030, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0018719843667341775, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08733055684958904, \"functional effect\": -2.0594, \"times_seen\": 1.0}, {\"site\": 1030, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1030, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010275228358958555, \"epitope\": \"all\", \"reference_site\": \"1033\", \"IC90\": 0.08682336243326506, \"functional effect\": -2.5961, \"times_seen\": 2.0}, {\"site\": 1031, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"F\", \"log2 fold change IC90\": -3.9571360437112366, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.005630061083200426, \"functional effect\": -1.0692, \"times_seen\": 6.0}, {\"site\": 1031, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0073220313433544505, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.0870012719004616, \"functional effect\": -1.2398, \"times_seen\": 15.0}, {\"site\": 1031, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"M\", \"log2 fold change IC90\": -0.04487959726135856, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.08476560144528966, \"functional effect\": 0.3887, \"times_seen\": 4.0}, {\"site\": 1031, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": null, \"functional effect\": -2.9507, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": null, \"functional effect\": -0.8952, \"times_seen\": null}, {\"site\": 1031, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004066047135617112, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.0871978447436377, \"functional effect\": 0.3651, \"times_seen\": 30.0}, {\"site\": 1031, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02275107897884836, \"epitope\": \"all\", \"reference_site\": \"1034\", \"IC90\": 0.08607578569630639, \"functional effect\": -0.9591, \"times_seen\": 1.0}, {\"site\": 1032, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": null, \"functional effect\": -2.7367, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"D\", \"log2 fold change IC90\": 0.015601248530846172, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08839469397255433, \"functional effect\": -2.6997, \"times_seen\": 3.0}, {\"site\": 1032, \"mutant\": \"E\", \"log2 fold change IC90\": -0.001253967814230673, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08736797521584229, \"functional effect\": -2.4806, \"times_seen\": 1.0}, {\"site\": 1032, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": null, \"functional effect\": -2.744, \"times_seen\": null}, {\"site\": 1032, \"mutant\": \"R\", \"log2 fold change IC90\": -0.014738819725829357, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08655515251943038, \"functional effect\": -2.7178, \"times_seen\": 5.0}, {\"site\": 1032, \"mutant\": \"V\", \"log2 fold change IC90\": -0.025023305215483634, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08594032413789841, \"functional effect\": -2.6825, \"times_seen\": 7.0}, {\"site\": 1032, \"mutant\": \"W\", \"log2 fold change IC90\": -0.008796665930194262, \"epitope\": \"all\", \"reference_site\": \"1035\", \"IC90\": 0.08691238995684157, \"functional effect\": -2.465, \"times_seen\": 5.0}, {\"site\": 1033, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -1.6874, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": null, \"functional effect\": -3.2597, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"N\", \"log2 fold change IC90\": -0.015024911702064093, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.08653799000148629, \"functional effect\": -2.558, \"times_seen\": 5.0}, {\"site\": 1033, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1033, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004981910908003577, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.0871425066430647, \"functional effect\": -2.933, \"times_seen\": 1.0}, {\"site\": 1033, \"mutant\": \"T\", \"log2 fold change IC90\": -0.010714534472308334, \"epitope\": \"all\", \"reference_site\": \"1036\", \"IC90\": 0.08679692841484118, \"functional effect\": -2.6751, \"times_seen\": 1.0}, {\"site\": 1034, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1034, \"mutant\": \"C\", \"log2 fold change IC90\": -0.008217369737417308, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08694729555008332, \"functional effect\": -0.7186, \"times_seen\": 1.0}, {\"site\": 1034, \"mutant\": \"G\", \"log2 fold change IC90\": 0.025947133734163796, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.0890308702262733, \"functional effect\": -1.4326, \"times_seen\": 2.0}, {\"site\": 1034, \"mutant\": \"I\", \"log2 fold change IC90\": -0.006204500777430072, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08706869033892976, \"functional effect\": -2.7668, \"times_seen\": 6.0}, {\"site\": 1034, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009005183870718069, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08689982910202966, \"functional effect\": -2.3881, \"times_seen\": 2.0}, {\"site\": 1034, \"mutant\": \"N\", \"log2 fold change IC90\": -0.05606938789377769, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.0841106879693074, \"functional effect\": -0.5421, \"times_seen\": 18.0}, {\"site\": 1034, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004188498267920122, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.08719044399614827, \"functional effect\": -2.4226, \"times_seen\": 1.0}, {\"site\": 1034, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": null, \"functional effect\": -2.9471, \"times_seen\": null}, {\"site\": 1034, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1037\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"E\", \"log2 fold change IC90\": 0.016996715116454193, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08848023631823833, \"functional effect\": -1.0333, \"times_seen\": 27.0}, {\"site\": 1035, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0010312669206133866, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08750647610324636, \"functional effect\": -1.7715, \"times_seen\": 1.0}, {\"site\": 1035, \"mutant\": \"I\", \"log2 fold change IC90\": 0.08937320102628162, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.0930323019631151, \"functional effect\": -0.3826, \"times_seen\": 14.0}, {\"site\": 1035, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": null, \"functional effect\": 0.1395, \"times_seen\": null}, {\"site\": 1035, \"mutant\": \"N\", \"log2 fold change IC90\": 1.1565699756039263, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.19493598082230792, \"functional effect\": -0.3265, \"times_seen\": 20.0}, {\"site\": 1035, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.000534682415078549, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08747636101920957, \"functional effect\": 0.0722, \"times_seen\": 25.0}, {\"site\": 1035, \"mutant\": \"R\", \"log2 fold change IC90\": 0.24006723903228472, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.10327547300802757, \"functional effect\": 0.2803, \"times_seen\": 49.0}, {\"site\": 1035, \"mutant\": \"T\", \"log2 fold change IC90\": 0.03327785754714292, \"epitope\": \"all\", \"reference_site\": \"1038\", \"IC90\": 0.08948441147156262, \"functional effect\": -0.1467, \"times_seen\": 12.0}, {\"site\": 1036, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"E\", \"log2 fold change IC90\": -0.004896651274575027, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.08714765669730731, \"functional effect\": -3.0763, \"times_seen\": 1.0}, {\"site\": 1036, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -2.5103, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0012389576029162934, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.08751907446080773, \"functional effect\": -2.479, \"times_seen\": 2.0}, {\"site\": 1036, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -2.9999, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1036, \"mutant\": \"S\", \"log2 fold change IC90\": -0.00341220050985615, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": 0.08723737280508637, \"functional effect\": -2.9133, \"times_seen\": 1.0}, {\"site\": 1036, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1039\", \"IC90\": null, \"functional effect\": -3.1583, \"times_seen\": null}, {\"site\": 1037, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1037, \"mutant\": \"A\", \"log2 fold change IC90\": -0.06592663371264067, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08353795865187, \"functional effect\": 0.0238, \"times_seen\": 22.0}, {\"site\": 1037, \"mutant\": \"F\", \"log2 fold change IC90\": -0.10020737149142535, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.0815763610066046, \"functional effect\": -0.9927, \"times_seen\": 22.0}, {\"site\": 1037, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03857332851175434, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08513693749879593, \"functional effect\": -2.6141, \"times_seen\": 2.0}, {\"site\": 1037, \"mutant\": \"L\", \"log2 fold change IC90\": -0.021662020603836398, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.08614078692196525, \"functional effect\": -2.0361, \"times_seen\": 5.0}, {\"site\": 1037, \"mutant\": \"M\", \"log2 fold change IC90\": 0.028088331641642435, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.0891631048585848, \"functional effect\": -2.0321, \"times_seen\": 9.0}, {\"site\": 1037, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04635177844718945, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.09029901822730482, \"functional effect\": -0.3684, \"times_seen\": 22.0}, {\"site\": 1037, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1040\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1038, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1038, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1038, \"mutant\": \"E\", \"log2 fold change IC90\": 0.009300066166030154, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08800945906854148, \"functional effect\": -0.3271, \"times_seen\": 16.0}, {\"site\": 1038, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03313754450271714, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08545832138691715, \"functional effect\": -0.9511, \"times_seen\": 126.0}, {\"site\": 1038, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0013662184411745257, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08736117770964885, \"functional effect\": -2.4891, \"times_seen\": 1.0}, {\"site\": 1038, \"mutant\": \"N\", \"log2 fold change IC90\": 0.027576516279801025, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08913147866481654, \"functional effect\": -2.072, \"times_seen\": 29.0}, {\"site\": 1038, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.026787407351615562, \"epitope\": \"all\", \"reference_site\": \"1041\", \"IC90\": 0.08908273987266514, \"functional effect\": -0.8159, \"times_seen\": 1.0}, {\"site\": 1039, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.9994, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.7063, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"L\", \"log2 fold change IC90\": -0.028287550131366298, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": 0.0857460951891445, \"functional effect\": -0.7176, \"times_seen\": 16.0}, {\"site\": 1039, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.9171, \"times_seen\": null}, {\"site\": 1039, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1042\", \"IC90\": null, \"functional effect\": -2.3389, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -2.9823, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -3.0004, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": null, \"functional effect\": -0.4876, \"times_seen\": null}, {\"site\": 1040, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005015214618279323, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.0871404950361661, \"functional effect\": -2.6105, \"times_seen\": 3.0}, {\"site\": 1040, \"mutant\": \"R\", \"log2 fold change IC90\": -0.010160118245464918, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08683029019384002, \"functional effect\": -1.6803, \"times_seen\": 6.0}, {\"site\": 1040, \"mutant\": \"S\", \"log2 fold change IC90\": -0.003892531479443593, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08720833282374027, \"functional effect\": -1.0532, \"times_seen\": 1.0}, {\"site\": 1040, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03334932046466108, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.08948884413080035, \"functional effect\": -2.4504, \"times_seen\": 5.0}, {\"site\": 1040, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.002850682895138401, \"epitope\": \"all\", \"reference_site\": \"1043\", \"IC90\": 0.0872713334511239, \"functional effect\": -2.8414, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": null, \"functional effect\": -3.0044, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"C\", \"log2 fold change IC90\": -0.013564353272771085, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.08662564386329305, \"functional effect\": -1.4106, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"D\", \"log2 fold change IC90\": -1.2412951723985983, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.036988155304383485, \"functional effect\": -2.8731, \"times_seen\": 4.0}, {\"site\": 1041, \"mutant\": \"E\", \"log2 fold change IC90\": -0.014644711733750662, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.08656079875585035, \"functional effect\": -2.2404, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": null, \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1041, \"mutant\": \"V\", \"log2 fold change IC90\": 0.025347610290975365, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.08899388042353555, \"functional effect\": -2.9256, \"times_seen\": 1.0}, {\"site\": 1041, \"mutant\": \"W\", \"log2 fold change IC90\": -0.04091992967981805, \"epitope\": \"all\", \"reference_site\": \"1044\", \"IC90\": 0.0849985714253587, \"functional effect\": -2.7309, \"times_seen\": 8.0}, {\"site\": 1042, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1042, \"mutant\": \"E\", \"log2 fold change IC90\": 0.057764799890532084, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.09101619808900244, \"functional effect\": -1.8822, \"times_seen\": 23.0}, {\"site\": 1042, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1042, \"mutant\": \"M\", \"log2 fold change IC90\": 0.05608269010117637, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.0909101396254083, \"functional effect\": -2.2214, \"times_seen\": 10.0}, {\"site\": 1042, \"mutant\": \"N\", \"log2 fold change IC90\": -0.16741822587057953, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.07786312770338151, \"functional effect\": -1.1793, \"times_seen\": 26.0}, {\"site\": 1042, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.21621506784007163, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.10158205018643493, \"functional effect\": -1.018, \"times_seen\": 15.0}, {\"site\": 1042, \"mutant\": \"R\", \"log2 fold change IC90\": -0.04182533797996699, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.08494524465420254, \"functional effect\": 0.1656, \"times_seen\": 52.0}, {\"site\": 1042, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07220333620269971, \"epitope\": \"all\", \"reference_site\": \"1045\", \"IC90\": 0.09193166436314232, \"functional effect\": -1.3548, \"times_seen\": 10.0}, {\"site\": 1043, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1043, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05361927911977952, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.09075504243473036, \"functional effect\": -1.1822, \"times_seen\": 12.0}, {\"site\": 1043, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": null, \"functional effect\": -1.1639, \"times_seen\": null}, {\"site\": 1043, \"mutant\": \"D\", \"log2 fold change IC90\": -1.260108695891921, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.036508941154188075, \"functional effect\": -2.8615, \"times_seen\": 4.0}, {\"site\": 1043, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1043, \"mutant\": \"S\", \"log2 fold change IC90\": -0.028239026630923883, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": 0.08574897921559574, \"functional effect\": -1.7674, \"times_seen\": 7.0}, {\"site\": 1043, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1046\", \"IC90\": null, \"functional effect\": -2.3598, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"*\", \"log2 fold change IC90\": -0.00838336956879491, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08693729176850644, \"functional effect\": -3.0069, \"times_seen\": 1.0}, {\"site\": 1044, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"C\", \"log2 fold change IC90\": -0.05027222179846621, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08444934901301021, \"functional effect\": -2.5979, \"times_seen\": 5.0}, {\"site\": 1044, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"F\", \"log2 fold change IC90\": 0.08578349112518, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.09280110698947297, \"functional effect\": -2.3915, \"times_seen\": 11.0}, {\"site\": 1044, \"mutant\": \"H\", \"log2 fold change IC90\": 0.018085751996753354, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08854705197614014, \"functional effect\": -2.6773, \"times_seen\": 5.0}, {\"site\": 1044, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06516850113877182, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.08358186917304976, \"functional effect\": -0.3012, \"times_seen\": 10.0}, {\"site\": 1044, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": null, \"functional effect\": -3.3118, \"times_seen\": null}, {\"site\": 1044, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1047\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -3.26, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -3.0083, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -2.8866, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": null, \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1045, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004888368680159901, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": 0.0871481570184051, \"functional effect\": -3.1124, \"times_seen\": 1.0}, {\"site\": 1045, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004183881463133024, \"epitope\": \"all\", \"reference_site\": \"1048\", \"IC90\": 0.08719072301693362, \"functional effect\": -3.0457, \"times_seen\": 1.0}, {\"site\": 1046, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": null, \"functional effect\": -0.2882, \"times_seen\": null}, {\"site\": 1046, \"mutant\": \"F\", \"log2 fold change IC90\": -0.00853059107838003, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08692842060312056, \"functional effect\": -2.8127, \"times_seen\": 2.0}, {\"site\": 1046, \"mutant\": \"I\", \"log2 fold change IC90\": 0.012323714301780067, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.0881941056396542, \"functional effect\": -2.1582, \"times_seen\": 13.0}, {\"site\": 1046, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1046, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0056770028799822455, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08710053140535157, \"functional effect\": -2.3985, \"times_seen\": 1.0}, {\"site\": 1046, \"mutant\": \"P\", \"log2 fold change IC90\": -0.00482126893494748, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08715221037337924, \"functional effect\": -2.9313, \"times_seen\": 1.0}, {\"site\": 1046, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": null, \"functional effect\": -2.3805, \"times_seen\": null}, {\"site\": 1046, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005592848220686242, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08710561226383104, \"functional effect\": -2.4874, \"times_seen\": 2.0}, {\"site\": 1046, \"mutant\": \"V\", \"log2 fold change IC90\": 0.008903811388025514, \"epitope\": \"all\", \"reference_site\": \"1049\", \"IC90\": 0.08798528945625624, \"functional effect\": -2.5783, \"times_seen\": 6.0}, {\"site\": 1047, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0988713838986361, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08165193864476165, \"functional effect\": -0.8474, \"times_seen\": 91.0}, {\"site\": 1047, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": null, \"functional effect\": -2.7832, \"times_seen\": null}, {\"site\": 1047, \"mutant\": \"L\", \"log2 fold change IC90\": -0.017940014194554474, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08636330830512044, \"functional effect\": -0.1566, \"times_seen\": 32.0}, {\"site\": 1047, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1047, \"mutant\": \"T\", \"log2 fold change IC90\": 0.016242519164027084, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08843399369960239, \"functional effect\": -2.1339, \"times_seen\": 7.0}, {\"site\": 1047, \"mutant\": \"V\", \"log2 fold change IC90\": -2.046550449014771, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.0211668718284575, \"functional effect\": -1.9149, \"times_seen\": 19.0}, {\"site\": 1047, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.02843079495305011, \"epitope\": \"all\", \"reference_site\": \"1050\", \"IC90\": 0.08573758190392812, \"functional effect\": -2.3353, \"times_seen\": 2.0}, {\"site\": 1048, \"mutant\": \"G\", \"log2 fold change IC90\": 0.02731376966574438, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08911524733308467, \"functional effect\": -2.1776, \"times_seen\": 2.0}, {\"site\": 1048, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": null, \"functional effect\": -3.2707, \"times_seen\": null}, {\"site\": 1048, \"mutant\": \"L\", \"log2 fold change IC90\": -0.003303483879559077, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08724394696684225, \"functional effect\": -2.77, \"times_seen\": 1.0}, {\"site\": 1048, \"mutant\": \"N\", \"log2 fold change IC90\": -0.009191969536796636, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08688857891311846, \"functional effect\": -2.9548, \"times_seen\": 2.0}, {\"site\": 1048, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004101826936983563, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.087195682205618, \"functional effect\": -2.9464, \"times_seen\": 1.0}, {\"site\": 1048, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1048, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003976680406930356, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08720324632004195, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1048, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0032024300681896775, \"epitope\": \"all\", \"reference_site\": \"1051\", \"IC90\": 0.08763826685904147, \"functional effect\": -2.7313, \"times_seen\": 1.0}, {\"site\": 1049, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0187457696078512, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08858757057676862, \"functional effect\": -2.9498, \"times_seen\": 1.0}, {\"site\": 1049, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1049, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02618127051792006, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08587137263841306, \"functional effect\": -2.9411, \"times_seen\": 5.0}, {\"site\": 1049, \"mutant\": \"L\", \"log2 fold change IC90\": -0.002190536459625378, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.0873112760869935, \"functional effect\": -1.1545, \"times_seen\": 22.0}, {\"site\": 1049, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005298758513456649, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08712337033080032, \"functional effect\": -0.6482, \"times_seen\": 1.0}, {\"site\": 1049, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01414013544828593, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08659107831167649, \"functional effect\": -2.4794, \"times_seen\": 2.0}, {\"site\": 1049, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06230128104914925, \"epitope\": \"all\", \"reference_site\": \"1052\", \"IC90\": 0.08374814541574555, \"functional effect\": -1.0543, \"times_seen\": 29.0}, {\"site\": 1051, \"mutant\": \"*\", \"log2 fold change IC90\": 0.14359003889110103, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 0.09659500328850099, \"functional effect\": -2.4716, \"times_seen\": 2.0}, {\"site\": 1051, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.999, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.7168, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.9766, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"L\", \"log2 fold change IC90\": 4.99916561431907, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 2.7965884265342718, \"functional effect\": -3.0239, \"times_seen\": 4.0}, {\"site\": 1051, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1051, \"mutant\": \"R\", \"log2 fold change IC90\": 0.17493177793415168, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": 0.09871643548093482, \"functional effect\": -2.2702, \"times_seen\": 1.0}, {\"site\": 1051, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1054\", \"IC90\": null, \"functional effect\": -2.5057, \"times_seen\": null}, {\"site\": 1052, \"mutant\": \"A\", \"log2 fold change IC90\": -0.05393704690334468, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08423509768299937, \"functional effect\": -0.0857, \"times_seen\": 16.0}, {\"site\": 1052, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0026592977651050745, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08728291146514118, \"functional effect\": -1.9005, \"times_seen\": 1.0}, {\"site\": 1052, \"mutant\": \"F\", \"log2 fold change IC90\": 0.023137152420165896, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08885763084033953, \"functional effect\": -1.8457, \"times_seen\": 2.0}, {\"site\": 1052, \"mutant\": \"L\", \"log2 fold change IC90\": 0.07885455087657417, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.09235647270992922, \"functional effect\": -2.3702, \"times_seen\": 11.0}, {\"site\": 1052, \"mutant\": \"P\", \"log2 fold change IC90\": -0.005844048983588262, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.0870904468333038, \"functional effect\": -2.4943, \"times_seen\": 1.0}, {\"site\": 1052, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1052, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1052, \"mutant\": \"V\", \"log2 fold change IC90\": 8.253705364023278e-05, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08744894993611245, \"functional effect\": -1.7888, \"times_seen\": 9.0}, {\"site\": 1052, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.032865597929485076, \"epitope\": \"all\", \"reference_site\": \"1055\", \"IC90\": 0.08945884436429445, \"functional effect\": -1.1067, \"times_seen\": 10.0}, {\"site\": 1053, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": null, \"functional effect\": -3.1635, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": null, \"functional effect\": -3.265, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1053, \"mutant\": \"S\", \"log2 fold change IC90\": 0.017502168138096373, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.0885112410952747, \"functional effect\": -2.8479, \"times_seen\": 1.0}, {\"site\": 1053, \"mutant\": \"T\", \"log2 fold change IC90\": -0.002550665924037334, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.08728948392853947, \"functional effect\": -2.9022, \"times_seen\": 3.0}, {\"site\": 1053, \"mutant\": \"V\", \"log2 fold change IC90\": -1.0420908533600808, \"epitope\": \"all\", \"reference_site\": \"1056\", \"IC90\": 0.042464806332399144, \"functional effect\": -1.5274, \"times_seen\": 41.0}, {\"site\": 1054, \"mutant\": \"H\", \"log2 fold change IC90\": -0.004177918930426139, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.08719108336932778, \"functional effect\": -2.98, \"times_seen\": 1.0}, {\"site\": 1054, \"mutant\": \"L\", \"log2 fold change IC90\": 0.18088222155792782, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.09912443552499259, \"functional effect\": -2.7923, \"times_seen\": 6.0}, {\"site\": 1054, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1054, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.00886222708075308, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.08690844044107177, \"functional effect\": -2.7854, \"times_seen\": 2.0}, {\"site\": 1054, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04879658064612858, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.09045216937242903, \"functional effect\": -0.7767, \"times_seen\": 1.0}, {\"site\": 1054, \"mutant\": \"T\", \"log2 fold change IC90\": -0.001071257842987874, \"epitope\": \"all\", \"reference_site\": \"1057\", \"IC90\": 0.08737904062512543, \"functional effect\": -2.3737, \"times_seen\": 8.0}, {\"site\": 1055, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1055, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": null, \"functional effect\": -1.911, \"times_seen\": null}, {\"site\": 1055, \"mutant\": \"N\", \"log2 fold change IC90\": -0.023616938442944404, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08602414125939196, \"functional effect\": -0.3326, \"times_seen\": 21.0}, {\"site\": 1055, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": null, \"functional effect\": -0.4864, \"times_seen\": null}, {\"site\": 1055, \"mutant\": \"R\", \"log2 fold change IC90\": -0.06836943073151995, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.0833966303713154, \"functional effect\": -0.5183, \"times_seen\": 61.0}, {\"site\": 1055, \"mutant\": \"S\", \"log2 fold change IC90\": 0.01827577812734669, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08855871581456633, \"functional effect\": -0.5405, \"times_seen\": 16.0}, {\"site\": 1055, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.11950732941384656, \"epitope\": \"all\", \"reference_site\": \"1058\", \"IC90\": 0.08049232313025234, \"functional effect\": -1.0804, \"times_seen\": 52.0}, {\"site\": 1056, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0005753143340076581, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08740908336882079, \"functional effect\": -2.1962, \"times_seen\": 2.0}, {\"site\": 1056, \"mutant\": \"E\", \"log2 fold change IC90\": -0.020849347949639507, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08618932384794231, \"functional effect\": -2.5641, \"times_seen\": 5.0}, {\"site\": 1056, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1056, \"mutant\": \"L\", \"log2 fold change IC90\": -0.010564251253438768, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08680597038201833, \"functional effect\": -2.5162, \"times_seen\": 6.0}, {\"site\": 1056, \"mutant\": \"R\", \"log2 fold change IC90\": 0.07349532915642795, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.09201402983822814, \"functional effect\": -2.4709, \"times_seen\": 5.0}, {\"site\": 1056, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004321360102673698, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08718241475321346, \"functional effect\": -2.5775, \"times_seen\": 1.0}, {\"site\": 1056, \"mutant\": \"W\", \"log2 fold change IC90\": 0.006437679522985337, \"epitope\": \"all\", \"reference_site\": \"1059\", \"IC90\": 0.08783501654989263, \"functional effect\": -2.9473, \"times_seen\": 4.0}, {\"site\": 1057, \"mutant\": \"A\", \"log2 fold change IC90\": -0.013732859806532384, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08661552659378081, \"functional effect\": -0.8753, \"times_seen\": 11.0}, {\"site\": 1057, \"mutant\": \"C\", \"log2 fold change IC90\": 0.04034433357600103, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08992379096317196, \"functional effect\": -0.6008, \"times_seen\": 15.0}, {\"site\": 1057, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": null, \"functional effect\": -2.9006, \"times_seen\": null}, {\"site\": 1057, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0105269014905276, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08680821772070721, \"functional effect\": -0.2763, \"times_seen\": 19.0}, {\"site\": 1057, \"mutant\": \"L\", \"log2 fold change IC90\": 1.7094895936943169, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.28598114313182266, \"functional effect\": -2.1423, \"times_seen\": 20.0}, {\"site\": 1057, \"mutant\": \"M\", \"log2 fold change IC90\": -0.01186703897177054, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.08672761792159199, \"functional effect\": -2.6312, \"times_seen\": 4.0}, {\"site\": 1057, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1060\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1058, \"mutant\": \"A\", \"log2 fold change IC90\": -0.01578812797263422, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.0864922216769165, \"functional effect\": -0.4204, \"times_seen\": 10.0}, {\"site\": 1058, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": null, \"functional effect\": -0.3743, \"times_seen\": null}, {\"site\": 1058, \"mutant\": \"F\", \"log2 fold change IC90\": -0.014395011814682114, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08657578189117769, \"functional effect\": -0.3203, \"times_seen\": 9.0}, {\"site\": 1058, \"mutant\": \"I\", \"log2 fold change IC90\": -0.03870591403432689, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08512911366468194, \"functional effect\": -1.0395, \"times_seen\": 12.0}, {\"site\": 1058, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00016373195104602312, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08745387170275498, \"functional effect\": 0.0117, \"times_seen\": 3.0}, {\"site\": 1058, \"mutant\": \"M\", \"log2 fold change IC90\": -0.001799665168705936, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.0873349346522112, \"functional effect\": -0.0322, \"times_seen\": 10.0}, {\"site\": 1058, \"mutant\": \"S\", \"log2 fold change IC90\": -0.022488432883467836, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.08609145742621191, \"functional effect\": -2.7374, \"times_seen\": 2.0}, {\"site\": 1058, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1061\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1059, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1059, \"mutant\": \"I\", \"log2 fold change IC90\": 0.006060180648939412, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.08781203644582429, \"functional effect\": -2.5942, \"times_seen\": 1.0}, {\"site\": 1059, \"mutant\": \"L\", \"log2 fold change IC90\": 0.7723213008932698, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.14935564120737466, \"functional effect\": -1.2258, \"times_seen\": 14.0}, {\"site\": 1059, \"mutant\": \"S\", \"log2 fold change IC90\": 0.006713153644379018, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.08785178973032294, \"functional effect\": -2.8525, \"times_seen\": 4.0}, {\"site\": 1059, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": null, \"functional effect\": -3.053, \"times_seen\": null}, {\"site\": 1059, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012615260134917967, \"epitope\": \"all\", \"reference_site\": \"1062\", \"IC90\": 0.08668265026523399, \"functional effect\": -0.6038, \"times_seen\": 2.0}, {\"site\": 1060, \"mutant\": \"*\", \"log2 fold change IC90\": -0.009642489219838322, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.0868614498924137, \"functional effect\": -2.6833, \"times_seen\": 3.0}, {\"site\": 1060, \"mutant\": \"A\", \"log2 fold change IC90\": 0.022239003179931913, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08880232977221071, \"functional effect\": -2.513, \"times_seen\": 10.0}, {\"site\": 1060, \"mutant\": \"C\", \"log2 fold change IC90\": -0.013673068054244559, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08661911640402024, \"functional effect\": -2.5841, \"times_seen\": 9.0}, {\"site\": 1060, \"mutant\": \"D\", \"log2 fold change IC90\": 0.04392947281132564, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.09014753209172618, \"functional effect\": -2.738, \"times_seen\": 6.0}, {\"site\": 1060, \"mutant\": \"E\", \"log2 fold change IC90\": -0.021512432898838498, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08614971900415201, \"functional effect\": -2.7019, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03267031971646753, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08548600202003873, \"functional effect\": -1.2671, \"times_seen\": 46.0}, {\"site\": 1060, \"mutant\": \"G\", \"log2 fold change IC90\": 0.001005747938133737, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.0875049282664426, \"functional effect\": -2.5585, \"times_seen\": 18.0}, {\"site\": 1060, \"mutant\": \"H\", \"log2 fold change IC90\": 0.014315633213899746, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08831595872348881, \"functional effect\": -2.5981, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"I\", \"log2 fold change IC90\": -0.05598417726352314, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08411565598832169, \"functional effect\": -1.4099, \"times_seen\": 31.0}, {\"site\": 1060, \"mutant\": \"K\", \"log2 fold change IC90\": -0.018924336111051966, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08630440444722828, \"functional effect\": -2.6852, \"times_seen\": 4.0}, {\"site\": 1060, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1060, \"mutant\": \"M\", \"log2 fold change IC90\": -0.023113047779964487, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08605419219260677, \"functional effect\": -0.7638, \"times_seen\": 22.0}, {\"site\": 1060, \"mutant\": \"N\", \"log2 fold change IC90\": -0.014939947201654018, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08654308662509176, \"functional effect\": -2.6918, \"times_seen\": 4.0}, {\"site\": 1060, \"mutant\": \"P\", \"log2 fold change IC90\": 0.062098067087341446, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.09128998457360679, \"functional effect\": -2.6696, \"times_seen\": 14.0}, {\"site\": 1060, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.011613290555373846, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08674287335017902, \"functional effect\": -2.8479, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"R\", \"log2 fold change IC90\": 0.011614229815691143, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.088150744454762, \"functional effect\": -2.7412, \"times_seen\": 16.0}, {\"site\": 1060, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0405788346984628, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08501866993053707, \"functional effect\": -2.5558, \"times_seen\": 15.0}, {\"site\": 1060, \"mutant\": \"T\", \"log2 fold change IC90\": 0.008829652274701557, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.0879807668487966, \"functional effect\": -2.7268, \"times_seen\": 7.0}, {\"site\": 1060, \"mutant\": \"V\", \"log2 fold change IC90\": 0.07997029652720837, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.09242792661173406, \"functional effect\": -1.8064, \"times_seen\": 58.0}, {\"site\": 1060, \"mutant\": \"W\", \"log2 fold change IC90\": 0.03588611333545717, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08964633712854482, \"functional effect\": -2.3231, \"times_seen\": 5.0}, {\"site\": 1060, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.023622770403063344, \"epitope\": \"all\", \"reference_site\": \"1063\", \"IC90\": 0.08888754577415295, \"functional effect\": -3.0762, \"times_seen\": 3.0}, {\"site\": 1061, \"mutant\": \"A\", \"log2 fold change IC90\": 0.00275985643076596, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.08761138630783251, \"functional effect\": -3.0111, \"times_seen\": 1.0}, {\"site\": 1061, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": null, \"functional effect\": -2.6745, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": null, \"functional effect\": -2.4501, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": null, \"functional effect\": -1.8627, \"times_seen\": null}, {\"site\": 1061, \"mutant\": \"R\", \"log2 fold change IC90\": 0.060441944635186054, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.09118524958440233, \"functional effect\": -2.0417, \"times_seen\": 1.0}, {\"site\": 1061, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007134532127451953, \"epitope\": \"all\", \"reference_site\": \"1064\", \"IC90\": 0.08701257971665412, \"functional effect\": -2.1372, \"times_seen\": 3.0}, {\"site\": 1062, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": null, \"functional effect\": -0.9906, \"times_seen\": null}, {\"site\": 1062, \"mutant\": \"A\", \"log2 fold change IC90\": -0.07647306875557154, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.08292950350082594, \"functional effect\": -0.3229, \"times_seen\": 31.0}, {\"site\": 1062, \"mutant\": \"C\", \"log2 fold change IC90\": 0.007151876274750525, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.08787850946537432, \"functional effect\": 0.125, \"times_seen\": 8.0}, {\"site\": 1062, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": null, \"functional effect\": -2.9248, \"times_seen\": null}, {\"site\": 1062, \"mutant\": \"L\", \"log2 fold change IC90\": -1.2234204680069303, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.03744928192085996, \"functional effect\": -0.6764, \"times_seen\": 90.0}, {\"site\": 1062, \"mutant\": \"M\", \"log2 fold change IC90\": 0.8624629981415037, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.15898530538291114, \"functional effect\": 0.4444, \"times_seen\": 47.0}, {\"site\": 1062, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1065\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1063, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": null, \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1063, \"mutant\": \"A\", \"log2 fold change IC90\": -0.056588746861774265, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.08408041422681724, \"functional effect\": -0.233, \"times_seen\": 22.0}, {\"site\": 1063, \"mutant\": \"D\", \"log2 fold change IC90\": -0.11379673682302974, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.08081156578518053, \"functional effect\": -0.4897, \"times_seen\": 36.0}, {\"site\": 1063, \"mutant\": \"I\", \"log2 fold change IC90\": -0.07253372148744128, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.08315625588350195, \"functional effect\": -1.4653, \"times_seen\": 29.0}, {\"site\": 1063, \"mutant\": \"N\", \"log2 fold change IC90\": 0.30026699135559703, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.10767605209843156, \"functional effect\": 0.2891, \"times_seen\": 104.0}, {\"site\": 1063, \"mutant\": \"P\", \"log2 fold change IC90\": 0.09171295575664051, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.09318330364269246, \"functional effect\": -2.9958, \"times_seen\": 4.0}, {\"site\": 1063, \"mutant\": \"S\", \"log2 fold change IC90\": -0.3393603175773703, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.06911496905278909, \"functional effect\": 0.2725, \"times_seen\": 44.0}, {\"site\": 1063, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1066\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -3.1347, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -1.3017, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -1.8727, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -2.9832, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"F\", \"log2 fold change IC90\": -2.7259653904884793, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.013216985183462161, \"functional effect\": -0.8799, \"times_seen\": 37.0}, {\"site\": 1064, \"mutant\": \"H\", \"log2 fold change IC90\": -0.0743924118214084, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.08304919084002711, \"functional effect\": -2.6468, \"times_seen\": 4.0}, {\"site\": 1064, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04337804328321034, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.08485387123334671, \"functional effect\": -2.9939, \"times_seen\": 2.0}, {\"site\": 1064, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": null, \"functional effect\": -3.0924, \"times_seen\": null}, {\"site\": 1064, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1067\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1065, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0029145565506757615, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08726746969923159, \"functional effect\": -2.4287, \"times_seen\": 6.0}, {\"site\": 1065, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1065, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0033651964898760824, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08724021510640269, \"functional effect\": -2.1319, \"times_seen\": 30.0}, {\"site\": 1065, \"mutant\": \"C\", \"log2 fold change IC90\": 0.15836780884456061, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09758952713012459, \"functional effect\": -1.0246, \"times_seen\": 58.0}, {\"site\": 1065, \"mutant\": \"D\", \"log2 fold change IC90\": 0.018896148652784477, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.0885968049667097, \"functional effect\": -2.55, \"times_seen\": 13.0}, {\"site\": 1065, \"mutant\": \"E\", \"log2 fold change IC90\": 0.12035027610300056, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09505146084426076, \"functional effect\": -2.4462, \"times_seen\": 16.0}, {\"site\": 1065, \"mutant\": \"F\", \"log2 fold change IC90\": -0.01686253266881153, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08642783311762907, \"functional effect\": -1.9872, \"times_seen\": 26.0}, {\"site\": 1065, \"mutant\": \"G\", \"log2 fold change IC90\": -1.338813889415703, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.03457057583031471, \"functional effect\": -2.5016, \"times_seen\": 11.0}, {\"site\": 1065, \"mutant\": \"H\", \"log2 fold change IC90\": -0.027444776449176457, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08579619979316158, \"functional effect\": -1.3264, \"times_seen\": 15.0}, {\"site\": 1065, \"mutant\": \"I\", \"log2 fold change IC90\": 0.09506345057669939, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09339996273169024, \"functional effect\": -0.0789, \"times_seen\": 56.0}, {\"site\": 1065, \"mutant\": \"K\", \"log2 fold change IC90\": 0.34416691411135103, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.11100289806144464, \"functional effect\": -1.1811, \"times_seen\": 21.0}, {\"site\": 1065, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0005228232530825408, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08741226372267816, \"functional effect\": -0.6599, \"times_seen\": 122.0}, {\"site\": 1065, \"mutant\": \"M\", \"log2 fold change IC90\": 0.017488665648180794, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08851041270360926, \"functional effect\": -1.4082, \"times_seen\": 35.0}, {\"site\": 1065, \"mutant\": \"N\", \"log2 fold change IC90\": 0.09522747656121995, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09341058236462609, \"functional effect\": -1.7039, \"times_seen\": 10.0}, {\"site\": 1065, \"mutant\": \"P\", \"log2 fold change IC90\": -0.01288888071486668, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08666621165047331, \"functional effect\": -2.59, \"times_seen\": 11.0}, {\"site\": 1065, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.08487582233794926, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09274273971572879, \"functional effect\": -0.6464, \"times_seen\": 33.0}, {\"site\": 1065, \"mutant\": \"R\", \"log2 fold change IC90\": 0.11923046346820572, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09497771100423892, \"functional effect\": -0.9362, \"times_seen\": 64.0}, {\"site\": 1065, \"mutant\": \"S\", \"log2 fold change IC90\": 0.11340487728249211, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.09459496536750887, \"functional effect\": -2.2309, \"times_seen\": 36.0}, {\"site\": 1065, \"mutant\": \"T\", \"log2 fold change IC90\": 0.020583465369728913, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08870048475982094, \"functional effect\": -1.7788, \"times_seen\": 29.0}, {\"site\": 1065, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1065, \"mutant\": \"W\", \"log2 fold change IC90\": -0.04824509929360101, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08456809171043607, \"functional effect\": -2.3901, \"times_seen\": 8.0}, {\"site\": 1065, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006432009080796327, \"epitope\": \"all\", \"reference_site\": \"1068\", \"IC90\": 0.08705496097295808, \"functional effect\": -2.8595, \"times_seen\": 2.0}, {\"site\": 1066, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": null, \"functional effect\": -3.0038, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"H\", \"log2 fold change IC90\": -0.017265387524296134, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.0864037025769016, \"functional effect\": -2.8035, \"times_seen\": 6.0}, {\"site\": 1066, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0055776487701529156, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08710652996603527, \"functional effect\": -2.9453, \"times_seen\": 2.0}, {\"site\": 1066, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0021045840808433026, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08731647804251388, \"functional effect\": -2.8659, \"times_seen\": 1.0}, {\"site\": 1066, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": null, \"functional effect\": -2.9985, \"times_seen\": null}, {\"site\": 1066, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04787313259758164, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.09039429078399452, \"functional effect\": -2.1741, \"times_seen\": 32.0}, {\"site\": 1066, \"mutant\": \"T\", \"log2 fold change IC90\": 0.009937176523427991, \"epitope\": \"all\", \"reference_site\": \"1069\", \"IC90\": 0.08804833361867842, \"functional effect\": -1.1377, \"times_seen\": 15.0}, {\"site\": 1067, \"mutant\": \"-\", \"log2 fold change IC90\": 0.030602995083770092, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08931865451704878, \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1067, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1067, \"mutant\": \"C\", \"log2 fold change IC90\": 0.005547236419489777, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08778082079062675, \"functional effect\": -0.5238, \"times_seen\": 12.0}, {\"site\": 1067, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004554912983548332, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08716830223775011, \"functional effect\": -2.3483, \"times_seen\": 2.0}, {\"site\": 1067, \"mutant\": \"E\", \"log2 fold change IC90\": -0.05047976832656203, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08443720097893544, \"functional effect\": 0.2697, \"times_seen\": 23.0}, {\"site\": 1067, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0161664645844867, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08646954267488377, \"functional effect\": -0.4643, \"times_seen\": 34.0}, {\"site\": 1067, \"mutant\": \"M\", \"log2 fold change IC90\": -0.027968194140788872, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08576507810613901, \"functional effect\": 0.3362, \"times_seen\": 11.0}, {\"site\": 1067, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": null, \"functional effect\": -3.2631, \"times_seen\": null}, {\"site\": 1067, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": null, \"functional effect\": -3.0417, \"times_seen\": null}, {\"site\": 1067, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04588233877482633, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08470670579991751, \"functional effect\": -0.3005, \"times_seen\": 52.0}, {\"site\": 1067, \"mutant\": \"T\", \"log2 fold change IC90\": 0.04239808534912425, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.09005189333680384, \"functional effect\": 0.4444, \"times_seen\": 97.0}, {\"site\": 1067, \"mutant\": \"V\", \"log2 fold change IC90\": 0.03898233338296524, \"epitope\": \"all\", \"reference_site\": \"1070\", \"IC90\": 0.08983893697635194, \"functional effect\": 0.1886, \"times_seen\": 52.0}, {\"site\": 1068, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": null, \"functional effect\": -2.566, \"times_seen\": null}, {\"site\": 1068, \"mutant\": \"-\", \"log2 fold change IC90\": 0.03220320184064579, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08941777983893831, \"functional effect\": -1.0208, \"times_seen\": 1.0}, {\"site\": 1068, \"mutant\": \"E\", \"log2 fold change IC90\": 0.02110148281815551, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08873233948146621, \"functional effect\": -0.506, \"times_seen\": 24.0}, {\"site\": 1068, \"mutant\": \"H\", \"log2 fold change IC90\": 0.002434856218917862, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08759165205259183, \"functional effect\": -1.27, \"times_seen\": 45.0}, {\"site\": 1068, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0975855230355167, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.08172474671084062, \"functional effect\": -0.0109, \"times_seen\": 25.0}, {\"site\": 1068, \"mutant\": \"L\", \"log2 fold change IC90\": -0.40066624794879135, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.06623952262902662, \"functional effect\": -0.5261, \"times_seen\": 77.0}, {\"site\": 1068, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": null, \"functional effect\": -2.9223, \"times_seen\": null}, {\"site\": 1068, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1068, \"mutant\": \"R\", \"log2 fold change IC90\": 0.7239264514494294, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.14442864252566945, \"functional effect\": -0.2455, \"times_seen\": 77.0}, {\"site\": 1068, \"mutant\": \"T\", \"log2 fold change IC90\": 0.13809539069578397, \"epitope\": \"all\", \"reference_site\": \"1071\", \"IC90\": 0.09622781125580371, \"functional effect\": -1.2601, \"times_seen\": 9.0}, {\"site\": 1069, \"mutant\": \"*\", \"log2 fold change IC90\": -0.029539028148166366, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.0856717462655205, \"functional effect\": -1.382, \"times_seen\": 3.0}, {\"site\": 1069, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1069, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04418802280898099, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.0848062446689252, \"functional effect\": 0.4134, \"times_seen\": 9.0}, {\"site\": 1069, \"mutant\": \"D\", \"log2 fold change IC90\": 0.03938860752731374, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.0898642398823242, \"functional effect\": -1.3371, \"times_seen\": 21.0}, {\"site\": 1069, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1069, \"mutant\": \"G\", \"log2 fold change IC90\": -0.03326335656558843, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.08545086920984245, \"functional effect\": -1.4297, \"times_seen\": 3.0}, {\"site\": 1069, \"mutant\": \"H\", \"log2 fold change IC90\": 0.011048034710810804, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.08811615590623743, \"functional effect\": -0.3225, \"times_seen\": 1.0}, {\"site\": 1069, \"mutant\": \"K\", \"log2 fold change IC90\": -0.13129678560769673, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.07983723396804993, \"functional effect\": -1.5922, \"times_seen\": 52.0}, {\"site\": 1069, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.36091642709587385, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.11229913816703585, \"functional effect\": 0.1158, \"times_seen\": 50.0}, {\"site\": 1069, \"mutant\": \"R\", \"log2 fold change IC90\": -2.0104775709391864, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.021702796508428542, \"functional effect\": -2.3716, \"times_seen\": 9.0}, {\"site\": 1069, \"mutant\": \"V\", \"log2 fold change IC90\": -4.6732062986805545, \"epitope\": \"all\", \"reference_site\": \"1072\", \"IC90\": 0.0034273186246357805, \"functional effect\": -1.6824, \"times_seen\": 20.0}, {\"site\": 1070, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1070, \"mutant\": \"E\", \"log2 fold change IC90\": 0.013133113709616201, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08824359931853984, \"functional effect\": -0.3758, \"times_seen\": 54.0}, {\"site\": 1070, \"mutant\": \"H\", \"log2 fold change IC90\": -0.007128702305816524, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08701293132862362, \"functional effect\": -0.4496, \"times_seen\": 15.0}, {\"site\": 1070, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1070, \"mutant\": \"M\", \"log2 fold change IC90\": -0.8254580886211523, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.04934488122933083, \"functional effect\": -0.0038, \"times_seen\": 87.0}, {\"site\": 1070, \"mutant\": \"N\", \"log2 fold change IC90\": -0.07483178659344236, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08302390194505924, \"functional effect\": -0.4858, \"times_seen\": 39.0}, {\"site\": 1070, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01790989742775205, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08636511118839875, \"functional effect\": -0.013, \"times_seen\": 25.0}, {\"site\": 1070, \"mutant\": \"R\", \"log2 fold change IC90\": 0.23994117812390736, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.10326644931917024, \"functional effect\": 0.0736, \"times_seen\": 112.0}, {\"site\": 1070, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0694944985265063, \"epitope\": \"all\", \"reference_site\": \"1073\", \"IC90\": 0.08333161989783713, \"functional effect\": -0.6264, \"times_seen\": 50.0}, {\"site\": 1071, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1071, \"mutant\": \"D\", \"log2 fold change IC90\": 0.05746156854870104, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.09099706995528993, \"functional effect\": -0.441, \"times_seen\": 70.0}, {\"site\": 1071, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01081718126575086, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.0867907530907515, \"functional effect\": -0.3182, \"times_seen\": 11.0}, {\"site\": 1071, \"mutant\": \"H\", \"log2 fold change IC90\": 0.04333009804456494, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.09011008763390116, \"functional effect\": -0.6686, \"times_seen\": 22.0}, {\"site\": 1071, \"mutant\": \"I\", \"log2 fold change IC90\": 0.021821790462415742, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08877665275549616, \"functional effect\": 0.3058, \"times_seen\": 42.0}, {\"site\": 1071, \"mutant\": \"K\", \"log2 fold change IC90\": -0.02015273420901335, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08623095091631973, \"functional effect\": -0.648, \"times_seen\": 52.0}, {\"site\": 1071, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1071, \"mutant\": \"S\", \"log2 fold change IC90\": 0.001457457680611238, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08753233046586076, \"functional effect\": 0.4069, \"times_seen\": 65.0}, {\"site\": 1071, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04453784045898665, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.08478568375761338, \"functional effect\": 0.3442, \"times_seen\": 23.0}, {\"site\": 1071, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.004235622601723282, \"epitope\": \"all\", \"reference_site\": \"1074\", \"IC90\": 0.0877010518766909, \"functional effect\": -1.2563, \"times_seen\": 20.0}, {\"site\": 1072, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": null, \"functional effect\": -1.6129, \"times_seen\": null}, {\"site\": 1072, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1072, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": null, \"functional effect\": -2.793, \"times_seen\": null}, {\"site\": 1072, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07476850094830044, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08302754397354835, \"functional effect\": 0.1042, \"times_seen\": 27.0}, {\"site\": 1072, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008198109830747933, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08694845629988, \"functional effect\": -2.9691, \"times_seen\": 1.0}, {\"site\": 1072, \"mutant\": \"V\", \"log2 fold change IC90\": -0.07078996801667357, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08325682577012483, \"functional effect\": -1.3245, \"times_seen\": 29.0}, {\"site\": 1072, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05709964958683934, \"epitope\": \"all\", \"reference_site\": \"1075\", \"IC90\": 0.08405064403543859, \"functional effect\": -0.1886, \"times_seen\": 34.0}, {\"site\": 1073, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02824333123726263, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08917268483719337, \"functional effect\": -1.4501, \"times_seen\": 19.0}, {\"site\": 1073, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06485190952909833, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08360021277399095, \"functional effect\": -1.2811, \"times_seen\": 10.0}, {\"site\": 1073, \"mutant\": \"I\", \"log2 fold change IC90\": -0.13842521859040288, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.07944372691600898, \"functional effect\": 0.0389, \"times_seen\": 76.0}, {\"site\": 1073, \"mutant\": \"L\", \"log2 fold change IC90\": -0.006144008232662604, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08707234122627869, \"functional effect\": -0.1396, \"times_seen\": 2.0}, {\"site\": 1073, \"mutant\": \"N\", \"log2 fold change IC90\": -0.011131026299064598, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08677187461438765, \"functional effect\": -1.4546, \"times_seen\": 2.0}, {\"site\": 1073, \"mutant\": \"S\", \"log2 fold change IC90\": -0.011403297589420349, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.08675550021758921, \"functional effect\": -0.921, \"times_seen\": 66.0}, {\"site\": 1073, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1076\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"A\", \"log2 fold change IC90\": -0.08473748209627682, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.0824558036673523, \"functional effect\": 0.1939, \"times_seen\": 53.0}, {\"site\": 1074, \"mutant\": \"I\", \"log2 fold change IC90\": 0.022680145831745768, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08882948761504555, \"functional effect\": -2.176, \"times_seen\": 3.0}, {\"site\": 1074, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -2.5151, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -2.8967, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007964292063764812, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08696254918913093, \"functional effect\": -1.5999, \"times_seen\": 8.0}, {\"site\": 1074, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -0.9705, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": null, \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01979838489840127, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.08625213323826682, \"functional effect\": -0.8197, \"times_seen\": 14.0}, {\"site\": 1074, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1074, \"mutant\": \"V\", \"log2 fold change IC90\": -0.15538868858641872, \"epitope\": \"all\", \"reference_site\": \"1077\", \"IC90\": 0.07851508344212534, \"functional effect\": -2.5227, \"times_seen\": 7.0}, {\"site\": 1075, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005617837026623297, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08710410352752268, \"functional effect\": -2.9785, \"times_seen\": 1.0}, {\"site\": 1075, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1075, \"mutant\": \"C\", \"log2 fold change IC90\": 0.017285266589152488, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08849793489982445, \"functional effect\": -0.7531, \"times_seen\": 20.0}, {\"site\": 1075, \"mutant\": \"D\", \"log2 fold change IC90\": -0.015761171298332946, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08649383779422873, \"functional effect\": -3.0754, \"times_seen\": 3.0}, {\"site\": 1075, \"mutant\": \"E\", \"log2 fold change IC90\": -0.010614804569757065, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08680292867696628, \"functional effect\": -2.0433, \"times_seen\": 2.0}, {\"site\": 1075, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009457392992044856, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08687259483828356, \"functional effect\": -2.4729, \"times_seen\": 8.0}, {\"site\": 1075, \"mutant\": \"G\", \"log2 fold change IC90\": -0.04505375800484368, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08475536924187224, \"functional effect\": -0.6183, \"times_seen\": 53.0}, {\"site\": 1075, \"mutant\": \"H\", \"log2 fold change IC90\": -0.02102083978084756, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08617907921126913, \"functional effect\": -2.7754, \"times_seen\": 6.0}, {\"site\": 1075, \"mutant\": \"I\", \"log2 fold change IC90\": -0.010211711499595218, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08682718504895598, \"functional effect\": -1.9792, \"times_seen\": 3.0}, {\"site\": 1075, \"mutant\": \"K\", \"log2 fold change IC90\": -0.013944831634120325, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08660280131074076, \"functional effect\": -3.0339, \"times_seen\": 2.0}, {\"site\": 1075, \"mutant\": \"L\", \"log2 fold change IC90\": -0.018087947123501515, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08635445312658886, \"functional effect\": -2.9199, \"times_seen\": 5.0}, {\"site\": 1075, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": null, \"functional effect\": -2.8288, \"times_seen\": null}, {\"site\": 1075, \"mutant\": \"N\", \"log2 fold change IC90\": -0.014716823807158181, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08655647218474774, \"functional effect\": -2.7906, \"times_seen\": 3.0}, {\"site\": 1075, \"mutant\": \"P\", \"log2 fold change IC90\": 0.00957848302950486, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08802644511297913, \"functional effect\": -2.6398, \"times_seen\": 1.0}, {\"site\": 1075, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.05500957975828161, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.09084254367831565, \"functional effect\": -2.6828, \"times_seen\": 2.0}, {\"site\": 1075, \"mutant\": \"R\", \"log2 fold change IC90\": -0.07189273696486574, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08319321013519085, \"functional effect\": -3.0061, \"times_seen\": 8.0}, {\"site\": 1075, \"mutant\": \"S\", \"log2 fold change IC90\": -2.027403287468442, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.02144966678829526, \"functional effect\": -0.437, \"times_seen\": 72.0}, {\"site\": 1075, \"mutant\": \"T\", \"log2 fold change IC90\": 1.2053894299955854, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.20164531109386027, \"functional effect\": -0.7051, \"times_seen\": 96.0}, {\"site\": 1075, \"mutant\": \"V\", \"log2 fold change IC90\": -0.017773717106714135, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08637326383559105, \"functional effect\": -2.1939, \"times_seen\": 28.0}, {\"site\": 1075, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": null, \"functional effect\": -3.1007, \"times_seen\": null}, {\"site\": 1075, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.014616834707234731, \"epitope\": \"all\", \"reference_site\": \"1078\", \"IC90\": 0.08656247137613914, \"functional effect\": -2.8147, \"times_seen\": 3.0}, {\"site\": 1076, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": null, \"functional effect\": -0.3029, \"times_seen\": null}, {\"site\": 1076, \"mutant\": \"H\", \"log2 fold change IC90\": -0.014786732421279878, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08655227802296232, \"functional effect\": -1.5482, \"times_seen\": 3.0}, {\"site\": 1076, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0050307204439238445, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08713955847090234, \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1076, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1076, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": null, \"functional effect\": -3.2643, \"times_seen\": null}, {\"site\": 1076, \"mutant\": \"S\", \"log2 fold change IC90\": -0.028935290146788962, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08570760562004182, \"functional effect\": -0.5505, \"times_seen\": 19.0}, {\"site\": 1076, \"mutant\": \"T\", \"log2 fold change IC90\": 0.007772473497459971, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.08791631987508704, \"functional effect\": 0.2181, \"times_seen\": 44.0}, {\"site\": 1076, \"mutant\": \"V\", \"log2 fold change IC90\": 0.057470742074425464, \"epitope\": \"all\", \"reference_site\": \"1079\", \"IC90\": 0.09099764857141628, \"functional effect\": -2.3128, \"times_seen\": 1.0}, {\"site\": 1077, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1077, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0017841247724643006, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08755215251314656, \"functional effect\": -1.1145, \"times_seen\": 5.0}, {\"site\": 1077, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": null, \"functional effect\": -0.3397, \"times_seen\": null}, {\"site\": 1077, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": null, \"functional effect\": -3.2625, \"times_seen\": null}, {\"site\": 1077, \"mutant\": \"S\", \"log2 fold change IC90\": -0.01801158255884171, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.0863590241513468, \"functional effect\": -0.4165, \"times_seen\": 27.0}, {\"site\": 1077, \"mutant\": \"T\", \"log2 fold change IC90\": -0.011336497276220395, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08675951730269198, \"functional effect\": -2.092, \"times_seen\": 11.0}, {\"site\": 1077, \"mutant\": \"V\", \"log2 fold change IC90\": 0.003873115025526689, \"epitope\": \"all\", \"reference_site\": \"1080\", \"IC90\": 0.08767901790489738, \"functional effect\": -2.1791, \"times_seen\": 5.0}, {\"site\": 1078, \"mutant\": \"F\", \"log2 fold change IC90\": 0.2542010773454758, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.10429221758346542, \"functional effect\": -0.4039, \"times_seen\": 57.0}, {\"site\": 1078, \"mutant\": \"H\", \"log2 fold change IC90\": 0.04161147783098192, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.09000280729516957, \"functional effect\": -2.9388, \"times_seen\": 5.0}, {\"site\": 1078, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1078, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03470578315485603, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08536547693633532, \"functional effect\": -0.7406, \"times_seen\": 7.0}, {\"site\": 1078, \"mutant\": \"M\", \"log2 fold change IC90\": 0.028768330435442323, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08920514083508738, \"functional effect\": -0.0659, \"times_seen\": 23.0}, {\"site\": 1078, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": null, \"functional effect\": -3.0036, \"times_seen\": null}, {\"site\": 1078, \"mutant\": \"T\", \"log2 fold change IC90\": -0.027991114430209456, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08576371555567505, \"functional effect\": -1.4291, \"times_seen\": 10.0}, {\"site\": 1078, \"mutant\": \"V\", \"log2 fold change IC90\": 0.00416923711801934, \"epitope\": \"all\", \"reference_site\": \"1081\", \"IC90\": 0.08769701641345297, \"functional effect\": -0.3121, \"times_seen\": 30.0}, {\"site\": 1079, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -3.0716, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -3.0067, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -2.2886, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -2.9919, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"R\", \"log2 fold change IC90\": 0.023147924171889517, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": 0.08885829429026089, \"functional effect\": -2.469, \"times_seen\": 3.0}, {\"site\": 1079, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": null, \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1079, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010964613082256363, \"epitope\": \"all\", \"reference_site\": \"1082\", \"IC90\": 0.08678188422780127, \"functional effect\": -2.5589, \"times_seen\": 2.0}, {\"site\": 1080, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": null, \"functional effect\": -2.6875, \"times_seen\": null}, {\"site\": 1080, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1080, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1080, \"mutant\": \"N\", \"log2 fold change IC90\": 0.01583610261706054, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.08840908477886798, \"functional effect\": -0.003, \"times_seen\": 6.0}, {\"site\": 1080, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.002480898197968253, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.08759444748561666, \"functional effect\": -0.7085, \"times_seen\": 4.0}, {\"site\": 1080, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00021260678021477772, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.08743106162450337, \"functional effect\": -0.1981, \"times_seen\": 2.0}, {\"site\": 1080, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.06971996791454096, \"epitope\": \"all\", \"reference_site\": \"1083\", \"IC90\": 0.09177355485621151, \"functional effect\": -0.163, \"times_seen\": 9.0}, {\"site\": 1081, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0031643066562831086, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08763595103656491, \"functional effect\": -0.2165, \"times_seen\": 5.0}, {\"site\": 1081, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1081, \"mutant\": \"E\", \"log2 fold change IC90\": -0.056674187112215745, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08407543490774708, \"functional effect\": -0.1137, \"times_seen\": 25.0}, {\"site\": 1081, \"mutant\": \"G\", \"log2 fold change IC90\": -0.027479039232818425, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.0857941622303773, \"functional effect\": -0.0057, \"times_seen\": 18.0}, {\"site\": 1081, \"mutant\": \"H\", \"log2 fold change IC90\": -1.9109801059566642, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.023252380431078242, \"functional effect\": 0.2472, \"times_seen\": 6.0}, {\"site\": 1081, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": null, \"functional effect\": -0.189, \"times_seen\": null}, {\"site\": 1081, \"mutant\": \"N\", \"log2 fold change IC90\": 0.09360264717876358, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.0933054382988732, \"functional effect\": 0.2612, \"times_seen\": 17.0}, {\"site\": 1081, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": null, \"functional effect\": -0.0339, \"times_seen\": null}, {\"site\": 1081, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01573664821795521, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.0864953080379765, \"functional effect\": -0.2983, \"times_seen\": 8.0}, {\"site\": 1081, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.002905573097414939, \"epitope\": \"all\", \"reference_site\": \"1084\", \"IC90\": 0.08762023577605557, \"functional effect\": -0.239, \"times_seen\": 3.0}, {\"site\": 1082, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02564023467939097, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08901193304056287, \"functional effect\": 0.0323, \"times_seen\": 25.0}, {\"site\": 1082, \"mutant\": \"C\", \"log2 fold change IC90\": -0.005066112433663474, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08713742080185685, \"functional effect\": -1.0749, \"times_seen\": 1.0}, {\"site\": 1082, \"mutant\": \"D\", \"log2 fold change IC90\": -0.06284673629880563, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08371648783751079, \"functional effect\": 0.1623, \"times_seen\": 48.0}, {\"site\": 1082, \"mutant\": \"E\", \"log2 fold change IC90\": -0.08134622003243334, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08264985587035696, \"functional effect\": -0.0241, \"times_seen\": 28.0}, {\"site\": 1082, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1082, \"mutant\": \"L\", \"log2 fold change IC90\": 0.011445561585810055, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08814043918545295, \"functional effect\": -0.1119, \"times_seen\": 5.0}, {\"site\": 1082, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00205515193120063, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.087319469884194, \"functional effect\": 0.1736, \"times_seen\": 15.0}, {\"site\": 1082, \"mutant\": \"S\", \"log2 fold change IC90\": 0.013579888860768583, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08827093091082318, \"functional effect\": -0.1385, \"times_seen\": 21.0}, {\"site\": 1082, \"mutant\": \"V\", \"log2 fold change IC90\": 0.020549868570663904, \"epitope\": \"all\", \"reference_site\": \"1085\", \"IC90\": 0.08869841916897862, \"functional effect\": -2.2934, \"times_seen\": 4.0}, {\"site\": 1083, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": null, \"functional effect\": -3.0347, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"E\", \"log2 fold change IC90\": -0.03865437079960754, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08513215513092792, \"functional effect\": -0.3973, \"times_seen\": 24.0}, {\"site\": 1083, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"I\", \"log2 fold change IC90\": -0.012165969061732387, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08670964959969167, \"functional effect\": -0.2824, \"times_seen\": 6.0}, {\"site\": 1083, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"L\", \"log2 fold change IC90\": -0.02680992895858756, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08583396209660712, \"functional effect\": -0.5523, \"times_seen\": 8.0}, {\"site\": 1083, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": null, \"functional effect\": -0.4516, \"times_seen\": null}, {\"site\": 1083, \"mutant\": \"N\", \"log2 fold change IC90\": 0.05141932425013955, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.0906167562124095, \"functional effect\": -0.7429, \"times_seen\": 15.0}, {\"site\": 1083, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.009470575029520631, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.08801986132212772, \"functional effect\": -0.4261, \"times_seen\": 13.0}, {\"site\": 1083, \"mutant\": \"R\", \"log2 fold change IC90\": 0.01537539337422094, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.0883808567898886, \"functional effect\": 0.1127, \"times_seen\": 52.0}, {\"site\": 1083, \"mutant\": \"T\", \"log2 fold change IC90\": -0.004852842243463228, \"epitope\": \"all\", \"reference_site\": \"1086\", \"IC90\": 0.0871503030725028, \"functional effect\": -0.0806, \"times_seen\": 2.0}, {\"site\": 1084, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"D\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": null, \"functional effect\": -2.078, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": null, \"functional effect\": -1.4293, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": null, \"functional effect\": -1.5309, \"times_seen\": null}, {\"site\": 1084, \"mutant\": \"S\", \"log2 fold change IC90\": 0.027559200865198367, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.08913040890356984, \"functional effect\": 0.0105, \"times_seen\": 13.0}, {\"site\": 1084, \"mutant\": \"T\", \"log2 fold change IC90\": -0.17295960202272456, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.07756462989682937, \"functional effect\": -1.0232, \"times_seen\": 20.0}, {\"site\": 1084, \"mutant\": \"V\", \"log2 fold change IC90\": -0.0009360350151154096, \"epitope\": \"all\", \"reference_site\": \"1087\", \"IC90\": 0.08738723098718292, \"functional effect\": -1.8206, \"times_seen\": 15.0}, {\"site\": 1085, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1085, \"mutant\": \"L\", \"log2 fold change IC90\": 0.00408891709462997, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.08769213414094496, \"functional effect\": -1.4304, \"times_seen\": 1.0}, {\"site\": 1085, \"mutant\": \"N\", \"log2 fold change IC90\": 0.007245010569869174, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.0878841827136959, \"functional effect\": -0.7507, \"times_seen\": 7.0}, {\"site\": 1085, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": null, \"functional effect\": -1.2344, \"times_seen\": null}, {\"site\": 1085, \"mutant\": \"R\", \"log2 fold change IC90\": 0.2931659628601259, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.10714736651551293, \"functional effect\": -0.1165, \"times_seen\": 7.0}, {\"site\": 1085, \"mutant\": \"T\", \"log2 fold change IC90\": -0.03066173250196777, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.08560510250205614, \"functional effect\": -0.3033, \"times_seen\": 8.0}, {\"site\": 1085, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.023434689360756343, \"epitope\": \"all\", \"reference_site\": \"1088\", \"IC90\": 0.0888759584517584, \"functional effect\": 0.2076, \"times_seen\": 64.0}, {\"site\": 1086, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1086, \"mutant\": \"I\", \"log2 fold change IC90\": -0.006883068576235295, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.08702774744003659, \"functional effect\": -1.8346, \"times_seen\": 2.0}, {\"site\": 1086, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01148623247620817, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.08675051312705312, \"functional effect\": -1.3854, \"times_seen\": 3.0}, {\"site\": 1086, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": null, \"functional effect\": -3.1209, \"times_seen\": null}, {\"site\": 1086, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": null, \"functional effect\": -0.1576, \"times_seen\": null}, {\"site\": 1086, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04295284430559927, \"epitope\": \"all\", \"reference_site\": \"1089\", \"IC90\": 0.0848788835163375, \"functional effect\": 0.394, \"times_seen\": 21.0}, {\"site\": 1087, \"mutant\": \"A\", \"log2 fold change IC90\": -0.014429313428281415, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08657372348407859, \"functional effect\": -0.1195, \"times_seen\": 2.0}, {\"site\": 1087, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03627188681819737, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08527285954663905, \"functional effect\": -1.4863, \"times_seen\": 9.0}, {\"site\": 1087, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1087, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02565678197218335, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.08901295398741806, \"functional effect\": -2.0288, \"times_seen\": 1.0}, {\"site\": 1087, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": null, \"functional effect\": -1.166, \"times_seen\": null}, {\"site\": 1087, \"mutant\": \"S\", \"log2 fold change IC90\": -0.18906407528011365, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.07670360838852171, \"functional effect\": -0.3631, \"times_seen\": 33.0}, {\"site\": 1087, \"mutant\": \"T\", \"log2 fold change IC90\": 0.024678800603009685, \"epitope\": \"all\", \"reference_site\": \"1090\", \"IC90\": 0.0889526338859079, \"functional effect\": -0.4244, \"times_seen\": 1.0}, {\"site\": 1088, \"mutant\": \"C\", \"log2 fold change IC90\": -0.01900054763666393, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08629984546808256, \"functional effect\": -1.6448, \"times_seen\": 7.0}, {\"site\": 1088, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0005328334942948288, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08741165720863028, \"functional effect\": -0.0665, \"times_seen\": 38.0}, {\"site\": 1088, \"mutant\": \"H\", \"log2 fold change IC90\": -0.011647500033951545, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08674081650988937, \"functional effect\": -0.3618, \"times_seen\": 5.0}, {\"site\": 1088, \"mutant\": \"K\", \"log2 fold change IC90\": -1.257426553659361, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.0365768787647673, \"functional effect\": 0.3108, \"times_seen\": 21.0}, {\"site\": 1088, \"mutant\": \"L\", \"log2 fold change IC90\": 0.021328327363891845, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08874629255485947, \"functional effect\": -1.0451, \"times_seen\": 5.0}, {\"site\": 1088, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00803747113396035, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08695813822429456, \"functional effect\": -1.0036, \"times_seen\": 4.0}, {\"site\": 1088, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1088, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03704514125389352, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08971838586526991, \"functional effect\": 0.2589, \"times_seen\": 12.0}, {\"site\": 1088, \"mutant\": \"T\", \"log2 fold change IC90\": -0.015531717184020861, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": 0.08650759534152949, \"functional effect\": 0.4125, \"times_seen\": 2.0}, {\"site\": 1088, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1091\", \"IC90\": null, \"functional effect\": -3.1836, \"times_seen\": null}, {\"site\": 1089, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": null, \"functional effect\": -2.1064, \"times_seen\": null}, {\"site\": 1089, \"mutant\": \"A\", \"log2 fold change IC90\": -0.014264302768477791, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08658362606489364, \"functional effect\": -0.5347, \"times_seen\": 8.0}, {\"site\": 1089, \"mutant\": \"D\", \"log2 fold change IC90\": -0.07356322130460718, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08309693717104405, \"functional effect\": 0.2621, \"times_seen\": 25.0}, {\"site\": 1089, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1089, \"mutant\": \"G\", \"log2 fold change IC90\": 0.001688723696906916, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08754636314455419, \"functional effect\": -1.3051, \"times_seen\": 24.0}, {\"site\": 1089, \"mutant\": \"K\", \"log2 fold change IC90\": 0.00624096962123392, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08782304115722803, \"functional effect\": -1.5301, \"times_seen\": 32.0}, {\"site\": 1089, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.02826964804750089, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.0857471592000877, \"functional effect\": -0.7884, \"times_seen\": 17.0}, {\"site\": 1089, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02917432818896799, \"epitope\": \"all\", \"reference_site\": \"1092\", \"IC90\": 0.08569340602796001, \"functional effect\": -0.9278, \"times_seen\": 13.0}, {\"site\": 1090, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": null, \"functional effect\": -0.8553, \"times_seen\": null}, {\"site\": 1090, \"mutant\": \"E\", \"log2 fold change IC90\": -0.03609064456712255, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.08528357284044832, \"functional effect\": -2.5162, \"times_seen\": 2.0}, {\"site\": 1090, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1090, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": null, \"functional effect\": -0.3222, \"times_seen\": null}, {\"site\": 1090, \"mutant\": \"R\", \"log2 fold change IC90\": -1.2628602271387808, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.036439377070833466, \"functional effect\": -0.8766, \"times_seen\": 26.0}, {\"site\": 1090, \"mutant\": \"S\", \"log2 fold change IC90\": -0.021591359075291236, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": 0.0861450061010482, \"functional effect\": -1.0177, \"times_seen\": 5.0}, {\"site\": 1090, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1093\", \"IC90\": null, \"functional effect\": -2.3225, \"times_seen\": null}, {\"site\": 1091, \"mutant\": \"A\", \"log2 fold change IC90\": -0.035871029860216105, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08529655614734882, \"functional effect\": -1.5209, \"times_seen\": 12.0}, {\"site\": 1091, \"mutant\": \"F\", \"log2 fold change IC90\": 0.015276860363541186, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08837482077099189, \"functional effect\": 0.223, \"times_seen\": 24.0}, {\"site\": 1091, \"mutant\": \"I\", \"log2 fold change IC90\": -0.036568426998408995, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08525533385354701, \"functional effect\": -1.4895, \"times_seen\": 9.0}, {\"site\": 1091, \"mutant\": \"L\", \"log2 fold change IC90\": -0.013242248017473377, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.0866449866137884, \"functional effect\": -2.3822, \"times_seen\": 5.0}, {\"site\": 1091, \"mutant\": \"M\", \"log2 fold change IC90\": 0.03277287806371898, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08945309516209268, \"functional effect\": -1.3913, \"times_seen\": 6.0}, {\"site\": 1091, \"mutant\": \"T\", \"log2 fold change IC90\": -0.016164069366651344, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.08646968623506586, \"functional effect\": -0.105, \"times_seen\": 6.0}, {\"site\": 1091, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1094\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": null, \"functional effect\": -3.0007, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"L\", \"log2 fold change IC90\": -0.044244979957578416, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": 0.08480289661102372, \"functional effect\": -0.5826, \"times_seen\": 35.0}, {\"site\": 1092, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": null, \"functional effect\": -2.9443, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": null, \"functional effect\": -1.1874, \"times_seen\": null}, {\"site\": 1092, \"mutant\": \"Y\", \"log2 fold change IC90\": 1.0033681994794235, \"epitope\": \"all\", \"reference_site\": \"1095\", \"IC90\": 0.17529667460462758, \"functional effect\": -0.2225, \"times_seen\": 25.0}, {\"site\": 1093, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": null, \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1093, \"mutant\": \"A\", \"log2 fold change IC90\": -0.061826798207416295, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08377569357534033, \"functional effect\": 0.3309, \"times_seen\": 13.0}, {\"site\": 1093, \"mutant\": \"E\", \"log2 fold change IC90\": 0.02304982465670228, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08885225236249046, \"functional effect\": -2.2618, \"times_seen\": 1.0}, {\"site\": 1093, \"mutant\": \"F\", \"log2 fold change IC90\": -0.02570492339541439, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08589973021486248, \"functional effect\": -2.2925, \"times_seen\": 2.0}, {\"site\": 1093, \"mutant\": \"I\", \"log2 fold change IC90\": -0.025408476047840238, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08591738284615738, \"functional effect\": 0.3568, \"times_seen\": 79.0}, {\"site\": 1093, \"mutant\": \"L\", \"log2 fold change IC90\": -0.12484285000511647, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08019518807284619, \"functional effect\": -0.4912, \"times_seen\": 22.0}, {\"site\": 1093, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03354800069975557, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.08543401139258205, \"functional effect\": -0.7564, \"times_seen\": 35.0}, {\"site\": 1093, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1096\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1094, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": null, \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1094, \"mutant\": \"A\", \"log2 fold change IC90\": 0.025481250669292986, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08900212452667218, \"functional effect\": -0.3257, \"times_seen\": 15.0}, {\"site\": 1094, \"mutant\": \"C\", \"log2 fold change IC90\": -0.07720508774402249, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08288743600136206, \"functional effect\": 0.4444, \"times_seen\": 23.0}, {\"site\": 1094, \"mutant\": \"G\", \"log2 fold change IC90\": -0.02966183565973527, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08566445388155415, \"functional effect\": 0.0757, \"times_seen\": 17.0}, {\"site\": 1094, \"mutant\": \"I\", \"log2 fold change IC90\": -0.003993389868736741, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.0872022363277468, \"functional effect\": -1.405, \"times_seen\": 1.0}, {\"site\": 1094, \"mutant\": \"L\", \"log2 fold change IC90\": 0.009682928324369804, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08803281810281104, \"functional effect\": -0.6398, \"times_seen\": 5.0}, {\"site\": 1094, \"mutant\": \"N\", \"log2 fold change IC90\": 0.2817581877847404, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.10630346454243618, \"functional effect\": 0.4231, \"times_seen\": 71.0}, {\"site\": 1094, \"mutant\": \"R\", \"log2 fold change IC90\": -0.013506574917893671, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08662911319484007, \"functional effect\": 0.158, \"times_seen\": 2.0}, {\"site\": 1094, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1094, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02383204976415243, \"epitope\": \"all\", \"reference_site\": \"1097\", \"IC90\": 0.08601131568873381, \"functional effect\": -2.1066, \"times_seen\": 8.0}, {\"site\": 1095, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": null, \"functional effect\": -1.1352, \"times_seen\": null}, {\"site\": 1095, \"mutant\": \"D\", \"log2 fold change IC90\": -0.005516391903657996, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08711022858993567, \"functional effect\": 0.4444, \"times_seen\": 11.0}, {\"site\": 1095, \"mutant\": \"H\", \"log2 fold change IC90\": 0.007695993397666312, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08791165938169938, \"functional effect\": -0.5034, \"times_seen\": 14.0}, {\"site\": 1095, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005497768242970318, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08711135309772484, \"functional effect\": -0.5287, \"times_seen\": 1.0}, {\"site\": 1095, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01314094245664378, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08665107100924353, \"functional effect\": -1.0252, \"times_seen\": 3.0}, {\"site\": 1095, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1095, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08407556232779718, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.0824936437149758, \"functional effect\": -0.536, \"times_seen\": 24.0}, {\"site\": 1095, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008879810537724794, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": 0.08690738121409225, \"functional effect\": -0.0463, \"times_seen\": 12.0}, {\"site\": 1095, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1098\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1096, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": null, \"functional effect\": -1.4413, \"times_seen\": null}, {\"site\": 1096, \"mutant\": \"A\", \"log2 fold change IC90\": -0.000428401995069033, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08741798485276302, \"functional effect\": 0.2974, \"times_seen\": 1.0}, {\"site\": 1096, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0016550848260969819, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08754432187707692, \"functional effect\": -0.8839, \"times_seen\": 27.0}, {\"site\": 1096, \"mutant\": \"D\", \"log2 fold change IC90\": -0.05061103969299241, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08442951835566853, \"functional effect\": -0.263, \"times_seen\": 140.0}, {\"site\": 1096, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1096, \"mutant\": \"K\", \"log2 fold change IC90\": -0.026457574186117657, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08585492820443393, \"functional effect\": -0.1589, \"times_seen\": 6.0}, {\"site\": 1096, \"mutant\": \"S\", \"log2 fold change IC90\": -0.023153802515118033, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08605176127950565, \"functional effect\": -0.217, \"times_seen\": 72.0}, {\"site\": 1096, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0006488535851932279, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08740462793331329, \"functional effect\": -0.2863, \"times_seen\": 13.0}, {\"site\": 1096, \"mutant\": \"V\", \"log2 fold change IC90\": 0.01427789044031649, \"epitope\": \"all\", \"reference_site\": \"1099\", \"IC90\": 0.08831364829367641, \"functional effect\": -0.5929, \"times_seen\": 28.0}, {\"site\": 1097, \"mutant\": \"A\", \"log2 fold change IC90\": -0.44355579135902756, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.06429928666167004, \"functional effect\": -0.0827, \"times_seen\": 32.0}, {\"site\": 1097, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0809389507888474, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.09249000540562201, \"functional effect\": -0.0143, \"times_seen\": 71.0}, {\"site\": 1097, \"mutant\": \"K\", \"log2 fold change IC90\": -0.019873965649755333, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.0862476147294388, \"functional effect\": 0.0987, \"times_seen\": 12.0}, {\"site\": 1097, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0630535282178788, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.08370448900752442, \"functional effect\": 0.1204, \"times_seen\": 4.0}, {\"site\": 1097, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06313779895639647, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.08369959980163164, \"functional effect\": -0.0231, \"times_seen\": 39.0}, {\"site\": 1097, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1100\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"D\", \"log2 fold change IC90\": 0.25536557348189987, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.10437643282546534, \"functional effect\": 0.0306, \"times_seen\": 83.0}, {\"site\": 1098, \"mutant\": \"E\", \"log2 fold change IC90\": -0.018297061860668363, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.0863419371896847, \"functional effect\": -0.1584, \"times_seen\": 19.0}, {\"site\": 1098, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1098, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015927787994908457, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.086483849206918, \"functional effect\": -0.1489, \"times_seen\": 17.0}, {\"site\": 1098, \"mutant\": \"N\", \"log2 fold change IC90\": 0.00629516969474591, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08782634061038104, \"functional effect\": -0.0334, \"times_seen\": 44.0}, {\"site\": 1098, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.5403328782245113, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.12717043499175393, \"functional effect\": -0.1925, \"times_seen\": 83.0}, {\"site\": 1098, \"mutant\": \"R\", \"log2 fold change IC90\": 0.014399423027917167, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08832108814616034, \"functional effect\": -0.0986, \"times_seen\": 24.0}, {\"site\": 1098, \"mutant\": \"T\", \"log2 fold change IC90\": 0.008700168276377958, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08797287080013026, \"functional effect\": -0.1924, \"times_seen\": 1.0}, {\"site\": 1098, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06485561926340115, \"epitope\": \"all\", \"reference_site\": \"1101\", \"IC90\": 0.08359999780535965, \"functional effect\": 0.0633, \"times_seen\": 127.0}, {\"site\": 1099, \"mutant\": \"*\", \"log2 fold change IC90\": -0.013473910768036522, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08663107459228635, \"functional effect\": -1.9349, \"times_seen\": 3.0}, {\"site\": 1099, \"mutant\": \"C\", \"log2 fold change IC90\": -0.004725319411524662, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08715800681052858, \"functional effect\": -2.729, \"times_seen\": 6.0}, {\"site\": 1099, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009037612391546568, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08689787581241065, \"functional effect\": 0.0646, \"times_seen\": 16.0}, {\"site\": 1099, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": null, \"functional effect\": -3.0591, \"times_seen\": null}, {\"site\": 1099, \"mutant\": \"L\", \"log2 fold change IC90\": 0.06919205739207308, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.0917399792488092, \"functional effect\": -1.6568, \"times_seen\": 28.0}, {\"site\": 1099, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": null, \"functional effect\": -2.8932, \"times_seen\": null}, {\"site\": 1099, \"mutant\": \"S\", \"log2 fold change IC90\": 0.025799106162797417, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08902173569192633, \"functional effect\": -2.9385, \"times_seen\": 2.0}, {\"site\": 1099, \"mutant\": \"T\", \"log2 fold change IC90\": -0.017355926078679418, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.08639828034930666, \"functional effect\": -2.2473, \"times_seen\": 6.0}, {\"site\": 1099, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1102\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"C\", \"log2 fold change IC90\": -0.054212507607557914, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.0842190158059314, \"functional effect\": -0.6281, \"times_seen\": 12.0}, {\"site\": 1100, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0023095737787611403, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08758404599647047, \"functional effect\": 0.0246, \"times_seen\": 1.0}, {\"site\": 1100, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02289008686132132, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08884241502556685, \"functional effect\": -0.1738, \"times_seen\": 52.0}, {\"site\": 1100, \"mutant\": \"S\", \"log2 fold change IC90\": -0.032523171405638054, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08549472164682648, \"functional effect\": 0.2814, \"times_seen\": 49.0}, {\"site\": 1100, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": null, \"functional effect\": 0.0507, \"times_seen\": null}, {\"site\": 1100, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.013068180325917132, \"epitope\": \"all\", \"reference_site\": \"1103\", \"IC90\": 0.08665544135458621, \"functional effect\": 0.4077, \"times_seen\": 5.0}, {\"site\": 1101, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1101, \"mutant\": \"A\", \"log2 fold change IC90\": -1.5309530418372042, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.030259863545728478, \"functional effect\": -1.4398, \"times_seen\": 3.0}, {\"site\": 1101, \"mutant\": \"E\", \"log2 fold change IC90\": 0.011143258467080789, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.08812197212382579, \"functional effect\": -0.0063, \"times_seen\": 5.0}, {\"site\": 1101, \"mutant\": \"I\", \"log2 fold change IC90\": -0.3614190275145047, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.06806624373506803, \"functional effect\": -0.1818, \"times_seen\": 19.0}, {\"site\": 1101, \"mutant\": \"L\", \"log2 fold change IC90\": -0.11643487979100513, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.08066392705864196, \"functional effect\": -0.4747, \"times_seen\": 29.0}, {\"site\": 1101, \"mutant\": \"M\", \"log2 fold change IC90\": 0.054410960117000036, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.0908048580629125, \"functional effect\": -0.0126, \"times_seen\": 8.0}, {\"site\": 1101, \"mutant\": \"T\", \"log2 fold change IC90\": 0.00020353789825488104, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.08745628470905731, \"functional effect\": -1.5585, \"times_seen\": 3.0}, {\"site\": 1101, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1104\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0033331667883062413, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": 0.08724215197385844, \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 1102, \"mutant\": \"I\", \"log2 fold change IC90\": 0.00019406562786330973, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": 0.08745571050118024, \"functional effect\": -3.1318, \"times_seen\": 1.0}, {\"site\": 1102, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": null, \"functional effect\": -2.867, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": null, \"functional effect\": -2.6567, \"times_seen\": null}, {\"site\": 1102, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1105\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"*\", \"log2 fold change IC90\": -0.007800536127374837, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08697242060443759, \"functional effect\": -2.9491, \"times_seen\": 1.0}, {\"site\": 1103, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": null, \"functional effect\": -2.0867, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"H\", \"log2 fold change IC90\": -0.38026647388266716, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.06718280583515424, \"functional effect\": -2.739, \"times_seen\": 4.0}, {\"site\": 1103, \"mutant\": \"K\", \"log2 fold change IC90\": -0.024348558364310498, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08598052773188322, \"functional effect\": -2.4537, \"times_seen\": 8.0}, {\"site\": 1103, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": null, \"functional effect\": -2.7148, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1103, \"mutant\": \"R\", \"log2 fold change IC90\": -0.011613516791357813, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08674285974761077, \"functional effect\": -2.9677, \"times_seen\": 2.0}, {\"site\": 1103, \"mutant\": \"T\", \"log2 fold change IC90\": -0.005583343028888216, \"epitope\": \"all\", \"reference_site\": \"1106\", \"IC90\": 0.08710618616077757, \"functional effect\": -2.1603, \"times_seen\": 1.0}, {\"site\": 1104, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": null, \"functional effect\": -1.1628, \"times_seen\": null}, {\"site\": 1104, \"mutant\": \"G\", \"log2 fold change IC90\": -0.05220654952225439, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.0843361974100526, \"functional effect\": -1.9585, \"times_seen\": 13.0}, {\"site\": 1104, \"mutant\": \"K\", \"log2 fold change IC90\": -0.060753575651206704, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08383803759941791, \"functional effect\": 0.0633, \"times_seen\": 59.0}, {\"site\": 1104, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03502035866197983, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.0853468652686278, \"functional effect\": 0.0679, \"times_seen\": 15.0}, {\"site\": 1104, \"mutant\": \"M\", \"log2 fold change IC90\": 1.1969776163983514, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.2004730138602421, \"functional effect\": 0.0667, \"times_seen\": 68.0}, {\"site\": 1104, \"mutant\": \"N\", \"log2 fold change IC90\": 0.07865538323324645, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.09234372354891111, \"functional effect\": -1.0549, \"times_seen\": 8.0}, {\"site\": 1104, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1104, \"mutant\": \"S\", \"log2 fold change IC90\": -0.4597951760668692, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.06357957389248971, \"functional effect\": -1.0861, \"times_seen\": 35.0}, {\"site\": 1104, \"mutant\": \"T\", \"log2 fold change IC90\": -0.01808539521860796, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08635460587442549, \"functional effect\": -1.7845, \"times_seen\": 5.0}, {\"site\": 1104, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0028184659383973173, \"epitope\": \"all\", \"reference_site\": \"1107\", \"IC90\": 0.08727328233712427, \"functional effect\": -1.3463, \"times_seen\": 1.0}, {\"site\": 1105, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0003375511425572734, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08746440897959806, \"functional effect\": -0.8893, \"times_seen\": 8.0}, {\"site\": 1105, \"mutant\": \"I\", \"log2 fold change IC90\": 1.7450722812220252, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.2931222961913241, \"functional effect\": 0.0578, \"times_seen\": 22.0}, {\"site\": 1105, \"mutant\": \"K\", \"log2 fold change IC90\": 0.009027522538828254, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08799283452143045, \"functional effect\": 0.1833, \"times_seen\": 2.0}, {\"site\": 1105, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1105, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": null, \"functional effect\": -1.8012, \"times_seen\": null}, {\"site\": 1105, \"mutant\": \"S\", \"log2 fold change IC90\": -0.005857991844418982, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08708960515569505, \"functional effect\": -2.3399, \"times_seen\": 20.0}, {\"site\": 1105, \"mutant\": \"T\", \"log2 fold change IC90\": 0.11757763099778275, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.09486896151057601, \"functional effect\": -2.3165, \"times_seen\": 10.0}, {\"site\": 1105, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012231829585793406, \"epitope\": \"all\", \"reference_site\": \"1108\", \"IC90\": 0.08670569130465824, \"functional effect\": -1.0527, \"times_seen\": 15.0}, {\"site\": 1106, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1106, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0652277929501496, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.08357843419999754, \"functional effect\": -1.3553, \"times_seen\": 10.0}, {\"site\": 1106, \"mutant\": \"L\", \"log2 fold change IC90\": -0.5305732839326691, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.060535659682353006, \"functional effect\": -0.8859, \"times_seen\": 26.0}, {\"site\": 1106, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": null, \"functional effect\": -2.9219, \"times_seen\": null}, {\"site\": 1106, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00725723459578089, \"epitope\": \"all\", \"reference_site\": \"1109\", \"IC90\": 0.08700517953575126, \"functional effect\": 0.2652, \"times_seen\": 18.0}, {\"site\": 1107, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": null, \"functional effect\": -1.6801, \"times_seen\": null}, {\"site\": 1107, \"mutant\": \"C\", \"log2 fold change IC90\": -0.018001880179007446, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.08635960493304229, \"functional effect\": -2.561, \"times_seen\": 2.0}, {\"site\": 1107, \"mutant\": \"F\", \"log2 fold change IC90\": 0.013660627315124883, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.08827587101094864, \"functional effect\": 0.066, \"times_seen\": 30.0}, {\"site\": 1107, \"mutant\": \"H\", \"log2 fold change IC90\": -0.11018994337037089, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.08101385058261945, \"functional effect\": -1.6806, \"times_seen\": 9.0}, {\"site\": 1107, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": null, \"functional effect\": -3.1111, \"times_seen\": null}, {\"site\": 1107, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1110\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1108, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": null, \"functional effect\": -2.946, \"times_seen\": null}, {\"site\": 1108, \"mutant\": \"A\", \"log2 fold change IC90\": 0.002218541570791926, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08757851972977711, \"functional effect\": -1.2492, \"times_seen\": 11.0}, {\"site\": 1108, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0029925026797318803, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08762551549197758, \"functional effect\": -1.7751, \"times_seen\": 12.0}, {\"site\": 1108, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1108, \"mutant\": \"G\", \"log2 fold change IC90\": 0.01162044115887619, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08815112397759182, \"functional effect\": -2.3871, \"times_seen\": 9.0}, {\"site\": 1108, \"mutant\": \"K\", \"log2 fold change IC90\": 0.21378240053384853, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.10141090722140059, \"functional effect\": -1.8824, \"times_seen\": 41.0}, {\"site\": 1108, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.016386985630494507, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.0864563265091664, \"functional effect\": -0.0614, \"times_seen\": 12.0}, {\"site\": 1108, \"mutant\": \"R\", \"log2 fold change IC90\": 0.03232443200885379, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08942529396191388, \"functional effect\": -1.9665, \"times_seen\": 4.0}, {\"site\": 1108, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0002713887440252451, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08742749935759635, \"functional effect\": -2.4665, \"times_seen\": 2.0}, {\"site\": 1108, \"mutant\": \"V\", \"log2 fold change IC90\": 0.00038575735079863306, \"epitope\": \"all\", \"reference_site\": \"1111\", \"IC90\": 0.08746733156395335, \"functional effect\": -2.7096, \"times_seen\": 1.0}, {\"site\": 1109, \"mutant\": \"L\", \"log2 fold change IC90\": -0.026794869906524417, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.0858348580481516, \"functional effect\": -2.4076, \"times_seen\": 11.0}, {\"site\": 1109, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1109, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.013538859594416459, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.08826842058124271, \"functional effect\": -0.7292, \"times_seen\": 43.0}, {\"site\": 1109, \"mutant\": \"S\", \"log2 fold change IC90\": 0.17283716965297394, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.0985732158630694, \"functional effect\": -0.9911, \"times_seen\": 22.0}, {\"site\": 1109, \"mutant\": \"T\", \"log2 fold change IC90\": -0.020715625944749985, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.08619731302307244, \"functional effect\": -1.7155, \"times_seen\": 10.0}, {\"site\": 1109, \"mutant\": \"V\", \"log2 fold change IC90\": 0.04007379085035963, \"epitope\": \"all\", \"reference_site\": \"1112\", \"IC90\": 0.08990692950189733, \"functional effect\": -1.9212, \"times_seen\": 7.0}, {\"site\": 1110, \"mutant\": \"*\", \"log2 fold change IC90\": 0.008253896721066828, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.0879456621959287, \"functional effect\": -1.6966, \"times_seen\": 2.0}, {\"site\": 1110, \"mutant\": \"E\", \"log2 fold change IC90\": 0.04096608334784369, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.08996255324091103, \"functional effect\": -0.8441, \"times_seen\": 15.0}, {\"site\": 1110, \"mutant\": \"H\", \"log2 fold change IC90\": -0.020167057141700893, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.08623009482827639, \"functional effect\": 0.4444, \"times_seen\": 20.0}, {\"site\": 1110, \"mutant\": \"K\", \"log2 fold change IC90\": -0.6418149575583039, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.056043364391403123, \"functional effect\": 0.3841, \"times_seen\": 26.0}, {\"site\": 1110, \"mutant\": \"L\", \"log2 fold change IC90\": -0.7005470647030912, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.05380765593813728, \"functional effect\": 0.4138, \"times_seen\": 48.0}, {\"site\": 1110, \"mutant\": \"M\", \"log2 fold change IC90\": 0.6685996744119107, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.1389947222126676, \"functional effect\": -0.2198, \"times_seen\": 13.0}, {\"site\": 1110, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": null, \"functional effect\": -2.7803, \"times_seen\": null}, {\"site\": 1110, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1110, \"mutant\": \"R\", \"log2 fold change IC90\": -0.08608533344890175, \"epitope\": \"all\", \"reference_site\": \"1113\", \"IC90\": 0.08237880453476791, \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1111, \"mutant\": \"F\", \"log2 fold change IC90\": -0.013708628056416372, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08661698141504483, \"functional effect\": -0.0523, \"times_seen\": 13.0}, {\"site\": 1111, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1111, \"mutant\": \"L\", \"log2 fold change IC90\": 0.036795404024347514, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08970285653903744, \"functional effect\": -0.1349, \"times_seen\": 25.0}, {\"site\": 1111, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02880359023019678, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08571543000386449, \"functional effect\": 0.397, \"times_seen\": 6.0}, {\"site\": 1111, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0061971609511288495, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08782037437588182, \"functional effect\": 0.2317, \"times_seen\": 9.0}, {\"site\": 1111, \"mutant\": \"S\", \"log2 fold change IC90\": -0.020247335733420798, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08622529669853644, \"functional effect\": 0.059, \"times_seen\": 7.0}, {\"site\": 1111, \"mutant\": \"T\", \"log2 fold change IC90\": 0.003205861264792701, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.08763847529150474, \"functional effect\": 0.1919, \"times_seen\": 16.0}, {\"site\": 1111, \"mutant\": \"V\", \"log2 fold change IC90\": -2.7800566913524176, \"epitope\": \"all\", \"reference_site\": \"1114\", \"IC90\": 0.012730612499561868, \"functional effect\": 0.1682, \"times_seen\": 31.0}, {\"site\": 1112, \"mutant\": \"C\", \"log2 fold change IC90\": -0.02280037148295802, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08607284479859939, \"functional effect\": -1.0514, \"times_seen\": 8.0}, {\"site\": 1112, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1112, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01706797767321468, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08641552635712808, \"functional effect\": -1.0997, \"times_seen\": 11.0}, {\"site\": 1112, \"mutant\": \"M\", \"log2 fold change IC90\": 0.02967731138545457, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08926136292020051, \"functional effect\": -1.5368, \"times_seen\": 1.0}, {\"site\": 1112, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": null, \"functional effect\": -2.671, \"times_seen\": null}, {\"site\": 1112, \"mutant\": \"S\", \"log2 fold change IC90\": -0.008165289516935396, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.08695043433959056, \"functional effect\": -1.4465, \"times_seen\": 1.0}, {\"site\": 1112, \"mutant\": \"T\", \"log2 fold change IC90\": -0.4573658082949295, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.06368672632817092, \"functional effect\": -1.0783, \"times_seen\": 40.0}, {\"site\": 1112, \"mutant\": \"V\", \"log2 fold change IC90\": -0.43103219679075644, \"epitope\": \"all\", \"reference_site\": \"1115\", \"IC90\": 0.06485987875469681, \"functional effect\": 0.0418, \"times_seen\": 50.0}, {\"site\": 1113, \"mutant\": \"A\", \"log2 fold change IC90\": -0.049768379660146765, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08447884698043036, \"functional effect\": 0.1899, \"times_seen\": 25.0}, {\"site\": 1113, \"mutant\": \"I\", \"log2 fold change IC90\": -0.09688960645672423, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08176417800010292, \"functional effect\": -1.9701, \"times_seen\": 23.0}, {\"site\": 1113, \"mutant\": \"N\", \"log2 fold change IC90\": -0.035270003663373926, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08533209806255693, \"functional effect\": -0.2024, \"times_seen\": 67.0}, {\"site\": 1113, \"mutant\": \"S\", \"log2 fold change IC90\": -1.679931044668807, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.027291041995956132, \"functional effect\": 0.2663, \"times_seen\": 25.0}, {\"site\": 1113, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1113, \"mutant\": \"V\", \"log2 fold change IC90\": -0.06823152287939156, \"epitope\": \"all\", \"reference_site\": \"1116\", \"IC90\": 0.08340460267284552, \"functional effect\": -1.6437, \"times_seen\": 8.0}, {\"site\": 1114, \"mutant\": \"*\", \"log2 fold change IC90\": 3.1359566001112005, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.7686820763120839, \"functional effect\": -2.7794, \"times_seen\": 7.0}, {\"site\": 1114, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05708099973414839, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09097306898568222, \"functional effect\": -0.4808, \"times_seen\": 123.0}, {\"site\": 1114, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03437039684276051, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08538532433292437, \"functional effect\": -0.3026, \"times_seen\": 56.0}, {\"site\": 1114, \"mutant\": \"D\", \"log2 fold change IC90\": -0.12353500596654966, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08026792025092659, \"functional effect\": -0.5538, \"times_seen\": 43.0}, {\"site\": 1114, \"mutant\": \"E\", \"log2 fold change IC90\": 0.06179524818042121, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09127082499274265, \"functional effect\": -0.3872, \"times_seen\": 45.0}, {\"site\": 1114, \"mutant\": \"F\", \"log2 fold change IC90\": -0.002382306133422406, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08729967104109891, \"functional effect\": -0.7441, \"times_seen\": 46.0}, {\"site\": 1114, \"mutant\": \"G\", \"log2 fold change IC90\": 0.5974084706856558, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.13230236944176402, \"functional effect\": -0.8119, \"times_seen\": 122.0}, {\"site\": 1114, \"mutant\": \"H\", \"log2 fold change IC90\": -0.06828300322886871, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08340162656121707, \"functional effect\": -1.1124, \"times_seen\": 33.0}, {\"site\": 1114, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0211968569175521, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08873820561842602, \"functional effect\": 0.0388, \"times_seen\": 86.0}, {\"site\": 1114, \"mutant\": \"K\", \"log2 fold change IC90\": 1.5973644061741399, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.26459665713362723, \"functional effect\": 0.2293, \"times_seen\": 20.0}, {\"site\": 1114, \"mutant\": \"L\", \"log2 fold change IC90\": 0.029241326260031043, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08923439204578891, \"functional effect\": 0.0931, \"times_seen\": 127.0}, {\"site\": 1114, \"mutant\": \"M\", \"log2 fold change IC90\": 0.06304904641002866, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09135017990550308, \"functional effect\": -0.1527, \"times_seen\": 39.0}, {\"site\": 1114, \"mutant\": \"N\", \"log2 fold change IC90\": -0.06445418958293021, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08362326272889092, \"functional effect\": 0.1167, \"times_seen\": 48.0}, {\"site\": 1114, \"mutant\": \"P\", \"log2 fold change IC90\": -0.08856139873597925, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08223754089034281, \"functional effect\": -0.5241, \"times_seen\": 67.0}, {\"site\": 1114, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.06752426870256506, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09163398699676428, \"functional effect\": -0.4067, \"times_seen\": 42.0}, {\"site\": 1114, \"mutant\": \"R\", \"log2 fold change IC90\": 0.11943345621624006, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.09499107567414213, \"functional effect\": 0.2972, \"times_seen\": 175.0}, {\"site\": 1114, \"mutant\": \"S\", \"log2 fold change IC90\": 0.008461066153243582, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.0879582920037584, \"functional effect\": -0.4777, \"times_seen\": 146.0}, {\"site\": 1114, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1114, \"mutant\": \"V\", \"log2 fold change IC90\": -0.014559056975034354, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.08656593814028418, \"functional effect\": 0.284, \"times_seen\": 92.0}, {\"site\": 1114, \"mutant\": \"W\", \"log2 fold change IC90\": -0.8001270412686777, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.05021893670321062, \"functional effect\": -1.7711, \"times_seen\": 18.0}, {\"site\": 1114, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.7451882054612209, \"epitope\": \"all\", \"reference_site\": \"1117\", \"IC90\": 0.14657292513219436, \"functional effect\": -0.4969, \"times_seen\": 43.0}, {\"site\": 1115, \"mutant\": \"*\", \"log2 fold change IC90\": -0.009696427664601657, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08685820243969329, \"functional effect\": -2.9791, \"times_seen\": 2.0}, {\"site\": 1115, \"mutant\": \"A\", \"log2 fold change IC90\": 0.3543730123177946, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.11179095318678102, \"functional effect\": -0.4849, \"times_seen\": 76.0}, {\"site\": 1115, \"mutant\": \"C\", \"log2 fold change IC90\": -0.1310750968945671, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.079849502932084, \"functional effect\": -0.8215, \"times_seen\": 31.0}, {\"site\": 1115, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1115, \"mutant\": \"E\", \"log2 fold change IC90\": -2.9512938705927882, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.011305812319883502, \"functional effect\": 0.1149, \"times_seen\": 53.0}, {\"site\": 1115, \"mutant\": \"F\", \"log2 fold change IC90\": 0.07306447031929257, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.09198655408112648, \"functional effect\": 0.2446, \"times_seen\": 33.0}, {\"site\": 1115, \"mutant\": \"G\", \"log2 fold change IC90\": -0.06845528189213707, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08339166779483012, \"functional effect\": 0.0924, \"times_seen\": 95.0}, {\"site\": 1115, \"mutant\": \"H\", \"log2 fold change IC90\": 1.1308102102545372, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.19148622855065717, \"functional effect\": 0.3279, \"times_seen\": 30.0}, {\"site\": 1115, \"mutant\": \"I\", \"log2 fold change IC90\": 0.054426802766072487, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.09080585522264369, \"functional effect\": 0.4012, \"times_seen\": 24.0}, {\"site\": 1115, \"mutant\": \"K\", \"log2 fold change IC90\": -0.019207456716435898, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08628746936591983, \"functional effect\": -0.4248, \"times_seen\": 9.0}, {\"site\": 1115, \"mutant\": \"L\", \"log2 fold change IC90\": 0.5232689824493405, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.12567515002530766, \"functional effect\": 0.317, \"times_seen\": 73.0}, {\"site\": 1115, \"mutant\": \"M\", \"log2 fold change IC90\": 1.3363696001988423, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.22080916110162457, \"functional effect\": 0.2603, \"times_seen\": 28.0}, {\"site\": 1115, \"mutant\": \"N\", \"log2 fold change IC90\": -0.058270895081184694, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08398243558839232, \"functional effect\": -2.699, \"times_seen\": 4.0}, {\"site\": 1115, \"mutant\": \"P\", \"log2 fold change IC90\": -0.5355771286738014, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.06032606144286321, \"functional effect\": -1.2134, \"times_seen\": 22.0}, {\"site\": 1115, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.11986398968861028, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.09501942743205474, \"functional effect\": 0.3173, \"times_seen\": 19.0}, {\"site\": 1115, \"mutant\": \"R\", \"log2 fold change IC90\": 0.001643714798652983, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08754363193402466, \"functional effect\": 0.2213, \"times_seen\": 77.0}, {\"site\": 1115, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06982573633934902, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08331248944112465, \"functional effect\": 0.0417, \"times_seen\": 71.0}, {\"site\": 1115, \"mutant\": \"T\", \"log2 fold change IC90\": -0.0005659847747915925, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08740964862400846, \"functional effect\": 0.3475, \"times_seen\": 41.0}, {\"site\": 1115, \"mutant\": \"V\", \"log2 fold change IC90\": -1.2518032065793019, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.036719726601018174, \"functional effect\": 0.3064, \"times_seen\": 92.0}, {\"site\": 1115, \"mutant\": \"W\", \"log2 fold change IC90\": -0.025557366420888177, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.08590851637698446, \"functional effect\": 0.4444, \"times_seen\": 25.0}, {\"site\": 1115, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.7154246683535023, \"epitope\": \"all\", \"reference_site\": \"1118\", \"IC90\": 0.14358002930450864, \"functional effect\": 0.3516, \"times_seen\": 54.0}, {\"site\": 1116, \"mutant\": \"D\", \"log2 fold change IC90\": 0.009131816168310604, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08799919582686119, \"functional effect\": -1.0119, \"times_seen\": 5.0}, {\"site\": 1116, \"mutant\": \"H\", \"log2 fold change IC90\": 0.013627168146422793, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08827382372934964, \"functional effect\": -0.995, \"times_seen\": 2.0}, {\"site\": 1116, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0009889842120345555, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08738402379601569, \"functional effect\": -2.0861, \"times_seen\": 2.0}, {\"site\": 1116, \"mutant\": \"K\", \"log2 fold change IC90\": 0.015190074856749784, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08836950473211258, \"functional effect\": -1.3586, \"times_seen\": 3.0}, {\"site\": 1116, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014969844519756675, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08654129319036886, \"functional effect\": -1.6105, \"times_seen\": 3.0}, {\"site\": 1116, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1116, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": null, \"functional effect\": -2.7984, \"times_seen\": null}, {\"site\": 1116, \"mutant\": \"S\", \"log2 fold change IC90\": -0.020182218786629562, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": 0.08622918861929037, \"functional effect\": -0.8817, \"times_seen\": 3.0}, {\"site\": 1116, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1119\", \"IC90\": null, \"functional effect\": -3.2216, \"times_seen\": null}, {\"site\": 1117, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0748455169586764, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.09210018413304956, \"functional effect\": -0.5789, \"times_seen\": 14.0}, {\"site\": 1117, \"mutant\": \"F\", \"log2 fold change IC90\": 0.024990488331600717, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08897185377563945, \"functional effect\": -1.8992, \"times_seen\": 1.0}, {\"site\": 1117, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0002917711887407023, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08742626418763053, \"functional effect\": -1.2336, \"times_seen\": 19.0}, {\"site\": 1117, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0024741488998468865, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08729411367251833, \"functional effect\": -1.2726, \"times_seen\": 2.0}, {\"site\": 1117, \"mutant\": \"S\", \"log2 fold change IC90\": 0.03649382798653986, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.08968410732036518, \"functional effect\": -0.4278, \"times_seen\": 18.0}, {\"site\": 1117, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1120\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1118, \"mutant\": \"C\", \"log2 fold change IC90\": -0.009078921394913802, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08689538768210489, \"functional effect\": -1.7205, \"times_seen\": 2.0}, {\"site\": 1118, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1118, \"mutant\": \"I\", \"log2 fold change IC90\": -0.008598428840420138, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08692433318984007, \"functional effect\": -1.0324, \"times_seen\": 2.0}, {\"site\": 1118, \"mutant\": \"L\", \"log2 fold change IC90\": 0.011412216976879287, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08813840204355645, \"functional effect\": -0.7748, \"times_seen\": 20.0}, {\"site\": 1118, \"mutant\": \"M\", \"log2 fold change IC90\": -0.005269346000721589, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08712514655050595, \"functional effect\": -0.6682, \"times_seen\": 1.0}, {\"site\": 1118, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": null, \"functional effect\": -2.5171, \"times_seen\": null}, {\"site\": 1118, \"mutant\": \"V\", \"log2 fold change IC90\": 0.02410493971950788, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.0889172582281292, \"functional effect\": -1.1454, \"times_seen\": 4.0}, {\"site\": 1118, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.012431715183319238, \"epitope\": \"all\", \"reference_site\": \"1121\", \"IC90\": 0.08669367905130032, \"functional effect\": 0.4125, \"times_seen\": 4.0}, {\"site\": 1119, \"mutant\": \"A\", \"log2 fold change IC90\": 0.02488716067105191, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08896548172608194, \"functional effect\": 0.0042, \"times_seen\": 2.0}, {\"site\": 1119, \"mutant\": \"C\", \"log2 fold change IC90\": -0.3491425450475158, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.06864791860115205, \"functional effect\": 0.0833, \"times_seen\": 12.0}, {\"site\": 1119, \"mutant\": \"E\", \"log2 fold change IC90\": -0.01133981353045614, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08675931787295948, \"functional effect\": -0.4705, \"times_seen\": 2.0}, {\"site\": 1119, \"mutant\": \"F\", \"log2 fold change IC90\": 0.03971908692234184, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08988482751904169, \"functional effect\": -0.004, \"times_seen\": 13.0}, {\"site\": 1119, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02572743675098597, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08589838975410963, \"functional effect\": -0.163, \"times_seen\": 23.0}, {\"site\": 1119, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03329826592164748, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.08544880155268426, \"functional effect\": -0.4456, \"times_seen\": 34.0}, {\"site\": 1119, \"mutant\": \"M\", \"log2 fold change IC90\": -0.044700240883895834, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.0847761401910771, \"functional effect\": -0.1848, \"times_seen\": 20.0}, {\"site\": 1119, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1122\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1120, \"mutant\": \"A\", \"log2 fold change IC90\": 0.029403489001609887, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08924442279139937, \"functional effect\": 0.2764, \"times_seen\": 11.0}, {\"site\": 1120, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1120, \"mutant\": \"F\", \"log2 fold change IC90\": 0.010571111065651631, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08808703143320343, \"functional effect\": -1.8543, \"times_seen\": 5.0}, {\"site\": 1120, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0030223129293646743, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.0872609518454433, \"functional effect\": -3.0152, \"times_seen\": 1.0}, {\"site\": 1120, \"mutant\": \"N\", \"log2 fold change IC90\": -0.048071172077151766, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08457828761395654, \"functional effect\": -1.1837, \"times_seen\": 16.0}, {\"site\": 1120, \"mutant\": \"P\", \"log2 fold change IC90\": -0.003315925283406359, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.08724319460236712, \"functional effect\": -2.4402, \"times_seen\": 1.0}, {\"site\": 1120, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1120, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04614835609309742, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.0846910882419835, \"functional effect\": -0.0177, \"times_seen\": 17.0}, {\"site\": 1120, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.016678698673458944, \"epitope\": \"all\", \"reference_site\": \"1123\", \"IC90\": 0.0884607345745015, \"functional effect\": -1.2961, \"times_seen\": 2.0}, {\"site\": 1121, \"mutant\": \"A\", \"log2 fold change IC90\": -0.07545392932074726, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08298810672870588, \"functional effect\": 0.0116, \"times_seen\": 22.0}, {\"site\": 1121, \"mutant\": \"C\", \"log2 fold change IC90\": -1.116667008866598, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.040325474653989, \"functional effect\": -0.3083, \"times_seen\": 52.0}, {\"site\": 1121, \"mutant\": \"D\", \"log2 fold change IC90\": 0.23331341332069988, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.1027931296002155, \"functional effect\": -0.0186, \"times_seen\": 50.0}, {\"site\": 1121, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1121, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03932428042956642, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08509263353422747, \"functional effect\": -0.2825, \"times_seen\": 17.0}, {\"site\": 1121, \"mutant\": \"S\", \"log2 fold change IC90\": -0.02822558798157334, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08574977796779093, \"functional effect\": 0.1842, \"times_seen\": 71.0}, {\"site\": 1121, \"mutant\": \"V\", \"log2 fold change IC90\": -0.012583226173007118, \"epitope\": \"all\", \"reference_site\": \"1124\", \"IC90\": 0.08668457500987281, \"functional effect\": -0.8127, \"times_seen\": 16.0}, {\"site\": 1122, \"mutant\": \"D\", \"log2 fold change IC90\": 0.009127321749176825, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.08799892168392577, \"functional effect\": -0.5036, \"times_seen\": 57.0}, {\"site\": 1122, \"mutant\": \"H\", \"log2 fold change IC90\": 1.2677154629769223, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.21054752137401275, \"functional effect\": -0.4432, \"times_seen\": 21.0}, {\"site\": 1122, \"mutant\": \"K\", \"log2 fold change IC90\": -0.29152075195904664, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.07144523385835848, \"functional effect\": -0.393, \"times_seen\": 79.0}, {\"site\": 1122, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1122, \"mutant\": \"S\", \"log2 fold change IC90\": 1.3326953128420207, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.22024751499945053, \"functional effect\": -0.5408, \"times_seen\": 19.0}, {\"site\": 1122, \"mutant\": \"T\", \"log2 fold change IC90\": -0.9558354943092646, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.04508110971843293, \"functional effect\": -1.063, \"times_seen\": 19.0}, {\"site\": 1122, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.026746531368142364, \"epitope\": \"all\", \"reference_site\": \"1125\", \"IC90\": 0.08583773405518931, \"functional effect\": -1.0489, \"times_seen\": 28.0}, {\"site\": 1123, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -3.2598, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0015518683881417103, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.08734993655745306, \"functional effect\": -0.724, \"times_seen\": 1.0}, {\"site\": 1123, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -2.9886, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0670103509268302, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.08347523054423533, \"functional effect\": -2.2172, \"times_seen\": 4.0}, {\"site\": 1123, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00586576000919322, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": 0.08708913622458873, \"functional effect\": -2.8921, \"times_seen\": 1.0}, {\"site\": 1123, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -3.1257, \"times_seen\": null}, {\"site\": 1123, \"mutant\": \"Y\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1126\", \"IC90\": null, \"functional effect\": -2.94, \"times_seen\": null}, {\"site\": 1124, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0526252538067674, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.09069253321728121, \"functional effect\": -0.1624, \"times_seen\": 11.0}, {\"site\": 1124, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1124, \"mutant\": \"E\", \"log2 fold change IC90\": 0.08062684636448346, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.09246999880901478, \"functional effect\": 0.008, \"times_seen\": 34.0}, {\"site\": 1124, \"mutant\": \"G\", \"log2 fold change IC90\": -0.12530390959353815, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.08016956321676015, \"functional effect\": 0.1577, \"times_seen\": 65.0}, {\"site\": 1124, \"mutant\": \"H\", \"log2 fold change IC90\": -0.637348902894582, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.05621712289830376, \"functional effect\": 0.02, \"times_seen\": 6.0}, {\"site\": 1124, \"mutant\": \"N\", \"log2 fold change IC90\": -0.19999319327104492, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.07612473656211384, \"functional effect\": -0.24, \"times_seen\": 62.0}, {\"site\": 1124, \"mutant\": \"V\", \"log2 fold change IC90\": -0.010857850733495654, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.08678830650025085, \"functional effect\": -1.2044, \"times_seen\": 17.0}, {\"site\": 1124, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.08225376825305965, \"epitope\": \"all\", \"reference_site\": \"1127\", \"IC90\": 0.09257433570549747, \"functional effect\": -0.3369, \"times_seen\": 58.0}, {\"site\": 1125, \"mutant\": \"A\", \"log2 fold change IC90\": -0.040862600602998664, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08500194912217761, \"functional effect\": -0.1722, \"times_seen\": 10.0}, {\"site\": 1125, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": null, \"functional effect\": -2.7083, \"times_seen\": null}, {\"site\": 1125, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03219907402263287, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08551392995303495, \"functional effect\": 0.2539, \"times_seen\": 37.0}, {\"site\": 1125, \"mutant\": \"I\", \"log2 fold change IC90\": -0.14083852771304703, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.07931094625175843, \"functional effect\": 0.2408, \"times_seen\": 80.0}, {\"site\": 1125, \"mutant\": \"L\", \"log2 fold change IC90\": 0.014859030109859351, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08834922955033592, \"functional effect\": 0.3979, \"times_seen\": 29.0}, {\"site\": 1125, \"mutant\": \"M\", \"log2 fold change IC90\": -0.03533396454713951, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.08532831500704881, \"functional effect\": 0.3325, \"times_seen\": 13.0}, {\"site\": 1125, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1128\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1126, \"mutant\": \"A\", \"log2 fold change IC90\": 0.00588787312978656, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.08780154928797258, \"functional effect\": -1.7693, \"times_seen\": 2.0}, {\"site\": 1126, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": null, \"functional effect\": -2.4619, \"times_seen\": null}, {\"site\": 1126, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": null, \"functional effect\": -2.9989, \"times_seen\": null}, {\"site\": 1126, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06655907620332244, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.08350134566403218, \"functional effect\": -0.1637, \"times_seen\": 40.0}, {\"site\": 1126, \"mutant\": \"L\", \"log2 fold change IC90\": 0.006514937560526853, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.0878397203455772, \"functional effect\": -2.1342, \"times_seen\": 13.0}, {\"site\": 1126, \"mutant\": \"M\", \"log2 fold change IC90\": -1.4055390464280608, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.033008085819177066, \"functional effect\": -2.6109, \"times_seen\": 3.0}, {\"site\": 1126, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1129\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1127, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": null, \"functional effect\": -3.0159, \"times_seen\": null}, {\"site\": 1127, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1127, \"mutant\": \"L\", \"log2 fold change IC90\": -0.005907736016485992, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.08708660235503726, \"functional effect\": -0.7439, \"times_seen\": 25.0}, {\"site\": 1127, \"mutant\": \"M\", \"log2 fold change IC90\": 0.779333985492866, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.1500833997971282, \"functional effect\": -0.1114, \"times_seen\": 63.0}, {\"site\": 1127, \"mutant\": \"N\", \"log2 fold change IC90\": 0.010839205745003308, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.08810340208545644, \"functional effect\": -1.8813, \"times_seen\": 1.0}, {\"site\": 1127, \"mutant\": \"S\", \"log2 fold change IC90\": 0.003645686480235503, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.08766519714633735, \"functional effect\": -1.3624, \"times_seen\": 1.0}, {\"site\": 1127, \"mutant\": \"T\", \"log2 fold change IC90\": -0.01647578682954736, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.0864510050871296, \"functional effect\": -1.3744, \"times_seen\": 21.0}, {\"site\": 1127, \"mutant\": \"V\", \"log2 fold change IC90\": 0.9002363581160621, \"epitope\": \"all\", \"reference_site\": \"1130\", \"IC90\": 0.16320291060175898, \"functional effect\": -1.21, \"times_seen\": 45.0}, {\"site\": 1128, \"mutant\": \"A\", \"log2 fold change IC90\": -0.17839233699685023, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.07727309519734067, \"functional effect\": -1.6676, \"times_seen\": 30.0}, {\"site\": 1128, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": null, \"functional effect\": -2.5563, \"times_seen\": null}, {\"site\": 1128, \"mutant\": \"D\", \"log2 fold change IC90\": -0.011180722758264885, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08676888563852435, \"functional effect\": -0.4444, \"times_seen\": 26.0}, {\"site\": 1128, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0013099201269777404, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08736458687295527, \"functional effect\": -1.1128, \"times_seen\": 15.0}, {\"site\": 1128, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1128, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004903591653553958, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.08714723745672451, \"functional effect\": -2.0817, \"times_seen\": 1.0}, {\"site\": 1128, \"mutant\": \"S\", \"log2 fold change IC90\": -0.004090405512387077, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": 0.0871963725128717, \"functional effect\": -1.5422, \"times_seen\": 2.0}, {\"site\": 1128, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1131\", \"IC90\": null, \"functional effect\": -2.8068, \"times_seen\": null}, {\"site\": 1129, \"mutant\": \"F\", \"log2 fold change IC90\": -0.03669746848655568, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08524770855308939, \"functional effect\": -1.7658, \"times_seen\": 11.0}, {\"site\": 1129, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1129, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014614678040840233, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08656260077736898, \"functional effect\": -0.4432, \"times_seen\": 16.0}, {\"site\": 1129, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": null, \"functional effect\": -0.3274, \"times_seen\": null}, {\"site\": 1129, \"mutant\": \"N\", \"log2 fold change IC90\": -0.003941028066692239, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08720540134112068, \"functional effect\": -1.5141, \"times_seen\": 1.0}, {\"site\": 1129, \"mutant\": \"T\", \"log2 fold change IC90\": 0.04034509547282777, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.08992383845253538, \"functional effect\": -1.5754, \"times_seen\": 10.0}, {\"site\": 1129, \"mutant\": \"V\", \"log2 fold change IC90\": 0.15602265664815604, \"epitope\": \"all\", \"reference_site\": \"1132\", \"IC90\": 0.0974310207401697, \"functional effect\": -1.005, \"times_seen\": 27.0}, {\"site\": 1130, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03962179908730432, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.08507508718165697, \"functional effect\": -0.0239, \"times_seen\": 24.0}, {\"site\": 1130, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": -0.2697, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"F\", \"log2 fold change IC90\": 0.38874232089902694, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.11448612391903833, \"functional effect\": -0.8393, \"times_seen\": 37.0}, {\"site\": 1130, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": -2.0997, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"I\", \"log2 fold change IC90\": -0.004952823888830135, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.08714426359185971, \"functional effect\": 0.0819, \"times_seen\": 20.0}, {\"site\": 1130, \"mutant\": \"L\", \"log2 fold change IC90\": -0.9974030778808206, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.043800746129612614, \"functional effect\": -0.4561, \"times_seen\": 48.0}, {\"site\": 1130, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0341293480117987, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.08539959190269551, \"functional effect\": -0.2285, \"times_seen\": 22.0}, {\"site\": 1130, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": null, \"functional effect\": 1.5161, \"times_seen\": null}, {\"site\": 1130, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1133\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1131, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1131, \"mutant\": \"D\", \"log2 fold change IC90\": -0.033679968311589745, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08542619684654702, \"functional effect\": 0.1632, \"times_seen\": 23.0}, {\"site\": 1131, \"mutant\": \"H\", \"log2 fold change IC90\": 0.034063113227567735, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08953313089409601, \"functional effect\": 0.2539, \"times_seen\": 18.0}, {\"site\": 1131, \"mutant\": \"I\", \"log2 fold change IC90\": -0.016557883954831307, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08644608569886066, \"functional effect\": -0.4037, \"times_seen\": 1.0}, {\"site\": 1131, \"mutant\": \"K\", \"log2 fold change IC90\": 0.02620252264095836, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08904663205300178, \"functional effect\": 0.3876, \"times_seen\": 8.0}, {\"site\": 1131, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1131, \"mutant\": \"S\", \"log2 fold change IC90\": -0.028916219366506433, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.08570873858416259, \"functional effect\": 0.1915, \"times_seen\": 19.0}, {\"site\": 1131, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05547075625707828, \"epitope\": \"all\", \"reference_site\": \"1134\", \"IC90\": 0.0841455960858563, \"functional effect\": 0.0579, \"times_seen\": 26.0}, {\"site\": 1132, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1132, \"mutant\": \"D\", \"log2 fold change IC90\": -0.10083339856746956, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08154097034485643, \"functional effect\": -0.2686, \"times_seen\": 54.0}, {\"site\": 1132, \"mutant\": \"G\", \"log2 fold change IC90\": -0.013107725728536431, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08665306609352628, \"functional effect\": 0.3392, \"times_seen\": 1.0}, {\"site\": 1132, \"mutant\": \"H\", \"log2 fold change IC90\": 0.25537368753551687, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.10437701986453453, \"functional effect\": 0.3287, \"times_seen\": 47.0}, {\"site\": 1132, \"mutant\": \"I\", \"log2 fold change IC90\": -0.1344531779866023, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.07966275345427241, \"functional effect\": 0.4444, \"times_seen\": 34.0}, {\"site\": 1132, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0033186458966675677, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08724303008057863, \"functional effect\": 0.1278, \"times_seen\": 29.0}, {\"site\": 1132, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1132, \"mutant\": \"S\", \"log2 fold change IC90\": -0.10657188595537888, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08121727584077591, \"functional effect\": 0.0169, \"times_seen\": 30.0}, {\"site\": 1132, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006997921810630142, \"epitope\": \"all\", \"reference_site\": \"1135\", \"IC90\": 0.08702081941981453, \"functional effect\": 0.4444, \"times_seen\": 40.0}, {\"site\": 1133, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": null, \"functional effect\": -2.4231, \"times_seen\": null}, {\"site\": 1133, \"mutant\": \"A\", \"log2 fold change IC90\": -0.06447814601894827, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.08362187414803798, \"functional effect\": 0.2773, \"times_seen\": 28.0}, {\"site\": 1133, \"mutant\": \"I\", \"log2 fold change IC90\": 0.059724243747394, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.09113989872562704, \"functional effect\": 0.3854, \"times_seen\": 73.0}, {\"site\": 1133, \"mutant\": \"K\", \"log2 fold change IC90\": -0.049312851630578136, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.0845055252163962, \"functional effect\": 0.1615, \"times_seen\": 30.0}, {\"site\": 1133, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1133, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.015919845403734676, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.08648432533508699, \"functional effect\": 0.1291, \"times_seen\": 23.0}, {\"site\": 1133, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": null, \"functional effect\": 0.8711, \"times_seen\": null}, {\"site\": 1133, \"mutant\": \"S\", \"log2 fold change IC90\": -0.1309111776386826, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.07985857596161583, \"functional effect\": 0.3655, \"times_seen\": 28.0}, {\"site\": 1133, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1136\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1134, \"mutant\": \"A\", \"log2 fold change IC90\": -0.00621325011475542, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08706816230562356, \"functional effect\": -0.6368, \"times_seen\": 1.0}, {\"site\": 1134, \"mutant\": \"F\", \"log2 fold change IC90\": -0.011186510931381162, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.0867685375176052, \"functional effect\": -0.3921, \"times_seen\": 26.0}, {\"site\": 1134, \"mutant\": \"G\", \"log2 fold change IC90\": -0.006009601171313849, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.087080453600931, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1134, \"mutant\": \"I\", \"log2 fold change IC90\": -0.1093997109174001, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08105823786377694, \"functional effect\": 0.1507, \"times_seen\": 32.0}, {\"site\": 1134, \"mutant\": \"M\", \"log2 fold change IC90\": -0.02930600611660582, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.08568558496054147, \"functional effect\": -0.5631, \"times_seen\": 11.0}, {\"site\": 1134, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1137\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1135, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": null, \"functional effect\": -2.7638, \"times_seen\": null}, {\"site\": 1135, \"mutant\": \"C\", \"log2 fold change IC90\": 0.05979333333122948, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.091144263451555, \"functional effect\": -1.7593, \"times_seen\": 2.0}, {\"site\": 1135, \"mutant\": \"D\", \"log2 fold change IC90\": 0.05283898664402558, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.0907059701584334, \"functional effect\": -0.6748, \"times_seen\": 1.0}, {\"site\": 1135, \"mutant\": \"F\", \"log2 fold change IC90\": 0.05457413667194855, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.09081512916073753, \"functional effect\": 0.2701, \"times_seen\": 31.0}, {\"site\": 1135, \"mutant\": \"H\", \"log2 fold change IC90\": 0.13671143722024856, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.09613554577052731, \"functional effect\": -0.3486, \"times_seen\": 28.0}, {\"site\": 1135, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01678557969922426, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.08643244327820084, \"functional effect\": 0.4337, \"times_seen\": 16.0}, {\"site\": 1135, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": null, \"functional effect\": -1.1135, \"times_seen\": null}, {\"site\": 1135, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1138\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1136, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1136, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02597641373652449, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08588356688703928, \"functional effect\": -1.913, \"times_seen\": 14.0}, {\"site\": 1136, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1136, \"mutant\": \"E\", \"log2 fold change IC90\": -2.2461741753372313, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.018431638778361393, \"functional effect\": -2.1192, \"times_seen\": 15.0}, {\"site\": 1136, \"mutant\": \"G\", \"log2 fold change IC90\": 0.034914562826229324, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08958598714313554, \"functional effect\": -1.0282, \"times_seen\": 26.0}, {\"site\": 1136, \"mutant\": \"H\", \"log2 fold change IC90\": 0.12986707979507833, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.0956805447537232, \"functional effect\": -0.2512, \"times_seen\": 63.0}, {\"site\": 1136, \"mutant\": \"I\", \"log2 fold change IC90\": 0.005381661297048713, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08777074694568138, \"functional effect\": -1.4491, \"times_seen\": 12.0}, {\"site\": 1136, \"mutant\": \"N\", \"log2 fold change IC90\": -0.35381953074361605, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.06842573340950275, \"functional effect\": 0.3553, \"times_seen\": 87.0}, {\"site\": 1136, \"mutant\": \"V\", \"log2 fold change IC90\": 0.003902413545103763, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08768079852480279, \"functional effect\": -1.6317, \"times_seen\": 9.0}, {\"site\": 1136, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.017896402494579782, \"epitope\": \"all\", \"reference_site\": \"1139\", \"IC90\": 0.08636591904925768, \"functional effect\": 0.2, \"times_seen\": 60.0}, {\"site\": 1137, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1137, \"mutant\": \"A\", \"log2 fold change IC90\": 0.029507432357818705, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.08925085290916157, \"functional effect\": 0.4051, \"times_seen\": 17.0}, {\"site\": 1137, \"mutant\": \"L\", \"log2 fold change IC90\": 0.010609882250069484, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.0880893987279781, \"functional effect\": 0.4109, \"times_seen\": 3.0}, {\"site\": 1137, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1137, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.023928825402491454, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.08890640448150189, \"functional effect\": 0.2334, \"times_seen\": 5.0}, {\"site\": 1137, \"mutant\": \"S\", \"log2 fold change IC90\": 0.44277819815738034, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.11885549686056146, \"functional effect\": 0.397, \"times_seen\": 21.0}, {\"site\": 1137, \"mutant\": \"T\", \"log2 fold change IC90\": 0.04408674741671162, \"epitope\": \"all\", \"reference_site\": \"1140\", \"IC90\": 0.09015736001097552, \"functional effect\": 0.3651, \"times_seen\": 9.0}, {\"site\": 1138, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1138, \"mutant\": \"F\", \"log2 fold change IC90\": 0.038180781884668745, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08978903694070867, \"functional effect\": -0.4315, \"times_seen\": 83.0}, {\"site\": 1138, \"mutant\": \"H\", \"log2 fold change IC90\": 0.03181436134822282, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08939368287637117, \"functional effect\": 0.169, \"times_seen\": 1.0}, {\"site\": 1138, \"mutant\": \"I\", \"log2 fold change IC90\": 0.010779264767447342, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08809974164843304, \"functional effect\": -0.965, \"times_seen\": 4.0}, {\"site\": 1138, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1138, \"mutant\": \"P\", \"log2 fold change IC90\": -0.007029220772605389, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08701893154212974, \"functional effect\": -2.5233, \"times_seen\": 2.0}, {\"site\": 1138, \"mutant\": \"R\", \"log2 fold change IC90\": -0.003025615639154739, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08726075208231811, \"functional effect\": 0.1736, \"times_seen\": 1.0}, {\"site\": 1138, \"mutant\": \"S\", \"log2 fold change IC90\": 0.08732064864591235, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.09290003707348586, \"functional effect\": -0.6613, \"times_seen\": 17.0}, {\"site\": 1138, \"mutant\": \"W\", \"log2 fold change IC90\": -0.014656579001157537, \"epitope\": \"all\", \"reference_site\": \"1141\", \"IC90\": 0.08656008673016802, \"functional effect\": -0.1245, \"times_seen\": 20.0}, {\"site\": 1139, \"mutant\": \"*\", \"log2 fold change IC90\": -0.01690036103994708, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.08642556695520932, \"functional effect\": -2.2672, \"times_seen\": 1.0}, {\"site\": 1139, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1139, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": null, \"functional effect\": -1.9059, \"times_seen\": null}, {\"site\": 1139, \"mutant\": \"K\", \"log2 fold change IC90\": -0.010923542338083023, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.08678435477576765, \"functional effect\": -0.0954, \"times_seen\": 2.0}, {\"site\": 1139, \"mutant\": \"L\", \"log2 fold change IC90\": -1.5983733612345208, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.028878286907358948, \"functional effect\": -0.777, \"times_seen\": 41.0}, {\"site\": 1139, \"mutant\": \"M\", \"log2 fold change IC90\": 0.01565115573281974, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.0883977518663056, \"functional effect\": -0.888, \"times_seen\": 18.0}, {\"site\": 1139, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1139, \"mutant\": \"R\", \"log2 fold change IC90\": -0.22383927497995504, \"epitope\": \"all\", \"reference_site\": \"1142\", \"IC90\": 0.07487682432826254, \"functional effect\": 0.397, \"times_seen\": 20.0}, {\"site\": 1140, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": null, \"functional effect\": 0.2359, \"times_seen\": null}, {\"site\": 1140, \"mutant\": \"A\", \"log2 fold change IC90\": 0.00805525775443621, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.08793355413956915, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1140, \"mutant\": \"H\", \"log2 fold change IC90\": -0.054144733475899605, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.0842229722933222, \"functional effect\": 0.4444, \"times_seen\": 45.0}, {\"site\": 1140, \"mutant\": \"L\", \"log2 fold change IC90\": 0.1928858680429925, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.09995262053667815, \"functional effect\": 0.394, \"times_seen\": 78.0}, {\"site\": 1140, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1140, \"mutant\": \"S\", \"log2 fold change IC90\": 1.0441224940567402, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.18031918785823, \"functional effect\": 0.4444, \"times_seen\": 41.0}, {\"site\": 1140, \"mutant\": \"T\", \"log2 fold change IC90\": 0.020990452220748013, \"epitope\": \"all\", \"reference_site\": \"1143\", \"IC90\": 0.08872551085498266, \"functional effect\": 0.4444, \"times_seen\": 8.0}, {\"site\": 1141, \"mutant\": \"*\", \"log2 fold change IC90\": -0.016944712278687116, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08642291010679225, \"functional effect\": -1.4739, \"times_seen\": 3.0}, {\"site\": 1141, \"mutant\": \"A\", \"log2 fold change IC90\": -0.04436074277900779, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08479609224250013, \"functional effect\": 0.2804, \"times_seen\": 33.0}, {\"site\": 1141, \"mutant\": \"D\", \"log2 fold change IC90\": 1.2392833225256215, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.20643874301501478, \"functional effect\": -0.8182, \"times_seen\": 55.0}, {\"site\": 1141, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1141, \"mutant\": \"G\", \"log2 fold change IC90\": 0.06015560600691888, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.09116715340493198, \"functional effect\": -0.2457, \"times_seen\": 1.0}, {\"site\": 1141, \"mutant\": \"K\", \"log2 fold change IC90\": -0.03228938844049757, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.08550857684731938, \"functional effect\": 0.4317, \"times_seen\": 107.0}, {\"site\": 1141, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.6728787283626554, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.13940759451977425, \"functional effect\": 0.4266, \"times_seen\": 30.0}, {\"site\": 1141, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04439124290791944, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.09017639064885406, \"functional effect\": 0.312, \"times_seen\": 20.0}, {\"site\": 1141, \"mutant\": \"V\", \"log2 fold change IC90\": -0.027862432601134843, \"epitope\": \"all\", \"reference_site\": \"1144\", \"IC90\": 0.0857713656297923, \"functional effect\": 0.3085, \"times_seen\": 51.0}, {\"site\": 1142, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1142, \"mutant\": \"M\", \"log2 fold change IC90\": 0.04639812894165235, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.09030191937499035, \"functional effect\": -0.6534, \"times_seen\": 6.0}, {\"site\": 1142, \"mutant\": \"P\", \"log2 fold change IC90\": -0.011064205764712762, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.0867758936739539, \"functional effect\": -2.2462, \"times_seen\": 1.0}, {\"site\": 1142, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.0046807798847035365, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": 0.0871606976330487, \"functional effect\": -1.3835, \"times_seen\": 2.0}, {\"site\": 1142, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": null, \"functional effect\": -1.545, \"times_seen\": null}, {\"site\": 1142, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1145\", \"IC90\": null, \"functional effect\": -2.4853, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"A\", \"log2 fold change IC90\": -0.03827695376954973, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.0851544290885859, \"functional effect\": 0.0804, \"times_seen\": 16.0}, {\"site\": 1143, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"E\", \"log2 fold change IC90\": 0.06509154580675654, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.09147960076152556, \"functional effect\": -0.0953, \"times_seen\": 83.0}, {\"site\": 1143, \"mutant\": \"G\", \"log2 fold change IC90\": 1.58529087746208, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.26239155833030287, \"functional effect\": -1.1339, \"times_seen\": 18.0}, {\"site\": 1143, \"mutant\": \"H\", \"log2 fold change IC90\": 0.06994411531730672, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.09178781455869665, \"functional effect\": -0.3235, \"times_seen\": 50.0}, {\"site\": 1143, \"mutant\": \"N\", \"log2 fold change IC90\": 0.07643553433564432, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.09220174518103626, \"functional effect\": -0.2148, \"times_seen\": 67.0}, {\"site\": 1143, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": null, \"functional effect\": -0.8795, \"times_seen\": null}, {\"site\": 1143, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.04104751766422901, \"epitope\": \"all\", \"reference_site\": \"1146\", \"IC90\": 0.08499105471768954, \"functional effect\": -1.1626, \"times_seen\": 49.0}, {\"site\": 1144, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1144, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0486730484058778, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08454300985210564, \"functional effect\": 0.4273, \"times_seen\": 22.0}, {\"site\": 1144, \"mutant\": \"F\", \"log2 fold change IC90\": -0.00929865030233956, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08688215413369643, \"functional effect\": -1.1498, \"times_seen\": 4.0}, {\"site\": 1144, \"mutant\": \"L\", \"log2 fold change IC90\": 0.48051555966480397, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.12200548330811235, \"functional effect\": -0.5645, \"times_seen\": 34.0}, {\"site\": 1144, \"mutant\": \"P\", \"log2 fold change IC90\": 0.06158042162356488, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.09125723519257163, \"functional effect\": -2.038, \"times_seen\": 9.0}, {\"site\": 1144, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1144, \"mutant\": \"T\", \"log2 fold change IC90\": 0.014772815143770827, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08834394998811186, \"functional effect\": -0.2766, \"times_seen\": 18.0}, {\"site\": 1144, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0018384171944755049, \"epitope\": \"all\", \"reference_site\": \"1147\", \"IC90\": 0.08733258879249124, \"functional effect\": -1.213, \"times_seen\": 3.0}, {\"site\": 1145, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1145, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1145, \"mutant\": \"I\", \"log2 fold change IC90\": -0.008883821311736548, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08690713960698083, \"functional effect\": -0.392, \"times_seen\": 3.0}, {\"site\": 1145, \"mutant\": \"L\", \"log2 fold change IC90\": -0.040601255504391705, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.0850173486725907, \"functional effect\": -0.3991, \"times_seen\": 27.0}, {\"site\": 1145, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": null, \"functional effect\": -2.774, \"times_seen\": null}, {\"site\": 1145, \"mutant\": \"V\", \"log2 fold change IC90\": 0.016008775698731374, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08841966690626833, \"functional effect\": -0.2699, \"times_seen\": 2.0}, {\"site\": 1145, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006634047258818123, \"epitope\": \"all\", \"reference_site\": \"1148\", \"IC90\": 0.08704277045888482, \"functional effect\": 0.1984, \"times_seen\": 1.0}, {\"site\": 1146, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": null, \"functional effect\": -2.7743, \"times_seen\": null}, {\"site\": 1146, \"mutant\": \"E\", \"log2 fold change IC90\": -0.012399461316436176, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08669561725553729, \"functional effect\": -1.6481, \"times_seen\": 3.0}, {\"site\": 1146, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1146, \"mutant\": \"M\", \"log2 fold change IC90\": -0.20709481629483262, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.07575093559872817, \"functional effect\": -0.5776, \"times_seen\": 78.0}, {\"site\": 1146, \"mutant\": \"N\", \"log2 fold change IC90\": 0.037096174275879516, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.0897215595653312, \"functional effect\": -1.8489, \"times_seen\": 25.0}, {\"site\": 1146, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.004695533205439835, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08715980631290386, \"functional effect\": -0.9531, \"times_seen\": 1.0}, {\"site\": 1146, \"mutant\": \"R\", \"log2 fold change IC90\": -0.01185913293115693, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08672809319455609, \"functional effect\": -0.0919, \"times_seen\": 57.0}, {\"site\": 1146, \"mutant\": \"T\", \"log2 fold change IC90\": -0.00313802123968776, \"epitope\": \"all\", \"reference_site\": \"1149\", \"IC90\": 0.08725395354564817, \"functional effect\": -2.3638, \"times_seen\": 1.0}, {\"site\": 1147, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006710288006142117, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08703817071303745, \"functional effect\": -2.9546, \"times_seen\": 1.0}, {\"site\": 1147, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05638548244860945, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.09092922181718976, \"functional effect\": -0.4162, \"times_seen\": 9.0}, {\"site\": 1147, \"mutant\": \"D\", \"log2 fold change IC90\": -0.2974972102237826, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.07114987950387346, \"functional effect\": -0.0334, \"times_seen\": 75.0}, {\"site\": 1147, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1147, \"mutant\": \"G\", \"log2 fold change IC90\": -0.051643804196783015, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08436910045396027, \"functional effect\": -0.078, \"times_seen\": 24.0}, {\"site\": 1147, \"mutant\": \"K\", \"log2 fold change IC90\": -0.8488935305916767, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.048549787905532396, \"functional effect\": -0.2965, \"times_seen\": 54.0}, {\"site\": 1147, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.028446986515156397, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.08573661966481812, \"functional effect\": -0.1427, \"times_seen\": 30.0}, {\"site\": 1147, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": null, \"functional effect\": -1.3916, \"times_seen\": null}, {\"site\": 1147, \"mutant\": \"V\", \"log2 fold change IC90\": -0.04304761659240841, \"epitope\": \"all\", \"reference_site\": \"1150\", \"IC90\": 0.0848733079085651, \"functional effect\": -0.6488, \"times_seen\": 29.0}, {\"site\": 1148, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": null, \"functional effect\": -2.9483, \"times_seen\": null}, {\"site\": 1148, \"mutant\": \"D\", \"log2 fold change IC90\": 0.20933240313860846, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.10109858688298926, \"functional effect\": 0.3094, \"times_seen\": 55.0}, {\"site\": 1148, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1148, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": null, \"functional effect\": 0.4444, \"times_seen\": null}, {\"site\": 1148, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01551953159909706, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.08650832602270021, \"functional effect\": -0.8579, \"times_seen\": 46.0}, {\"site\": 1148, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.015703341803621495, \"epitope\": \"all\", \"reference_site\": \"1151\", \"IC90\": 0.08840094950311893, \"functional effect\": -0.3312, \"times_seen\": 6.0}, {\"site\": 1149, \"mutant\": \"F\", \"log2 fold change IC90\": 0.024378845695521574, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08893414140845347, \"functional effect\": -0.2535, \"times_seen\": 3.0}, {\"site\": 1149, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0032971835088711128, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08724432796933468, \"functional effect\": -0.1685, \"times_seen\": 5.0}, {\"site\": 1149, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1149, \"mutant\": \"M\", \"log2 fold change IC90\": -0.011684087362710325, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08673861675565249, \"functional effect\": -0.0935, \"times_seen\": 3.0}, {\"site\": 1149, \"mutant\": \"P\", \"log2 fold change IC90\": 0.010449214006713423, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": 0.08807958904506942, \"functional effect\": -2.4196, \"times_seen\": 2.0}, {\"site\": 1149, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": null, \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 1149, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": null, \"functional effect\": -2.1789, \"times_seen\": null}, {\"site\": 1149, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1152\", \"IC90\": null, \"functional effect\": -3.2633, \"times_seen\": null}, {\"site\": 1150, \"mutant\": \"A\", \"log2 fold change IC90\": -0.18620879232205853, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.07685556522483397, \"functional effect\": -0.2024, \"times_seen\": 36.0}, {\"site\": 1150, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1150, \"mutant\": \"E\", \"log2 fold change IC90\": 0.009138612457001686, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08799961037694361, \"functional effect\": 0.1902, \"times_seen\": 26.0}, {\"site\": 1150, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07556921759691344, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08298147526937037, \"functional effect\": -0.1208, \"times_seen\": 48.0}, {\"site\": 1150, \"mutant\": \"H\", \"log2 fold change IC90\": -0.025939394404677317, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08588577067437056, \"functional effect\": 0.2916, \"times_seen\": 58.0}, {\"site\": 1150, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007985347320497358, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08696128003287396, \"functional effect\": 0.0225, \"times_seen\": 43.0}, {\"site\": 1150, \"mutant\": \"S\", \"log2 fold change IC90\": 0.009170445300835842, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.08800155209621228, \"functional effect\": 0.1762, \"times_seen\": 1.0}, {\"site\": 1150, \"mutant\": \"V\", \"log2 fold change IC90\": 0.004036060844347862, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.0876889214089735, \"functional effect\": 0.4035, \"times_seen\": 12.0}, {\"site\": 1150, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.3845506187160082, \"epitope\": \"all\", \"reference_site\": \"1153\", \"IC90\": 0.06698359953247388, \"functional effect\": 0.3282, \"times_seen\": 52.0}, {\"site\": 1151, \"mutant\": \"E\", \"log2 fold change IC90\": 0.051270192887018666, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.0906073896438999, \"functional effect\": 0.3145, \"times_seen\": 32.0}, {\"site\": 1151, \"mutant\": \"G\", \"log2 fold change IC90\": -0.00012828688071823648, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08743617177845957, \"functional effect\": 0.3651, \"times_seen\": 1.0}, {\"site\": 1151, \"mutant\": \"I\", \"log2 fold change IC90\": 0.033044263568480566, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08946992377530906, \"functional effect\": 0.3651, \"times_seen\": 36.0}, {\"site\": 1151, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1151, \"mutant\": \"N\", \"log2 fold change IC90\": -0.08037752722588652, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08270536947744704, \"functional effect\": 0.2984, \"times_seen\": 29.0}, {\"site\": 1151, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1151, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0333184570616318, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08544760566818228, \"functional effect\": 0.3142, \"times_seen\": 15.0}, {\"site\": 1151, \"mutant\": \"T\", \"log2 fold change IC90\": 0.005494008925266152, \"epitope\": \"all\", \"reference_site\": \"1154\", \"IC90\": 0.08777758222197005, \"functional effect\": 0.4344, \"times_seen\": 16.0}, {\"site\": 1152, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": null, \"functional effect\": -2.0697, \"times_seen\": null}, {\"site\": 1152, \"mutant\": \"C\", \"log2 fold change IC90\": 0.012578649716398205, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.08820969159988762, \"functional effect\": -1.3143, \"times_seen\": 3.0}, {\"site\": 1152, \"mutant\": \"F\", \"log2 fold change IC90\": 0.05513299216939432, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.09085031495121679, \"functional effect\": -0.2061, \"times_seen\": 38.0}, {\"site\": 1152, \"mutant\": \"H\", \"log2 fold change IC90\": 0.9262847803640983, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.1661763655407283, \"functional effect\": 0.3612, \"times_seen\": 83.0}, {\"site\": 1152, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": null, \"functional effect\": -0.7103, \"times_seen\": null}, {\"site\": 1152, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1155\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1153, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0033836562386307806, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08723909884683045, \"functional effect\": 0.0107, \"times_seen\": 1.0}, {\"site\": 1153, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1153, \"mutant\": \"I\", \"log2 fold change IC90\": -0.005613726563235894, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.0871043517010648, \"functional effect\": -0.2959, \"times_seen\": 1.0}, {\"site\": 1153, \"mutant\": \"L\", \"log2 fold change IC90\": -0.022842099017652565, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08607035532190772, \"functional effect\": -0.3184, \"times_seen\": 47.0}, {\"site\": 1153, \"mutant\": \"S\", \"log2 fold change IC90\": 0.04993467608291803, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.09052355231425054, \"functional effect\": -0.0529, \"times_seen\": 2.0}, {\"site\": 1153, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": null, \"functional effect\": -2.8933, \"times_seen\": null}, {\"site\": 1153, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.00195427265125841, \"epitope\": \"all\", \"reference_site\": \"1156\", \"IC90\": 0.08732557584073773, \"functional effect\": 0.4067, \"times_seen\": 1.0}, {\"site\": 1154, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": null, \"functional effect\": -2.8081, \"times_seen\": null}, {\"site\": 1154, \"mutant\": \"E\", \"log2 fold change IC90\": -0.0001492402346852437, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.08743490188586232, \"functional effect\": -0.3787, \"times_seen\": 43.0}, {\"site\": 1154, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": null, \"functional effect\": 0.4125, \"times_seen\": null}, {\"site\": 1154, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1154, \"mutant\": \"M\", \"log2 fold change IC90\": -0.13356099781839922, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.07971203310635391, \"functional effect\": -0.3254, \"times_seen\": 78.0}, {\"site\": 1154, \"mutant\": \"N\", \"log2 fold change IC90\": -0.2873772573039173, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.07165072320603671, \"functional effect\": -0.3259, \"times_seen\": 79.0}, {\"site\": 1154, \"mutant\": \"R\", \"log2 fold change IC90\": 0.07794213424798864, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.09229808133986549, \"functional effect\": -0.3548, \"times_seen\": 54.0}, {\"site\": 1154, \"mutant\": \"T\", \"log2 fold change IC90\": -0.04671780686875667, \"epitope\": \"all\", \"reference_site\": \"1157\", \"IC90\": 0.0846576661480693, \"functional effect\": -0.2959, \"times_seen\": 31.0}, {\"site\": 1155, \"mutant\": \"D\", \"log2 fold change IC90\": -0.09729525943234847, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.08174119100799723, \"functional effect\": -0.6253, \"times_seen\": 28.0}, {\"site\": 1155, \"mutant\": \"H\", \"log2 fold change IC90\": -0.3129354647903181, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.07039256511029938, \"functional effect\": -0.0871, \"times_seen\": 31.0}, {\"site\": 1155, \"mutant\": \"I\", \"log2 fold change IC90\": -0.016356736298641414, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.0864581392786393, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1155, \"mutant\": \"K\", \"log2 fold change IC90\": 0.28104945009826615, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.10625125477782171, \"functional effect\": -0.656, \"times_seen\": 25.0}, {\"site\": 1155, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1155, \"mutant\": \"S\", \"log2 fold change IC90\": 0.8334045385513923, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.1558150909269265, \"functional effect\": -0.6445, \"times_seen\": 85.0}, {\"site\": 1155, \"mutant\": \"T\", \"log2 fold change IC90\": -0.009982635776038168, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.0868409728411492, \"functional effect\": -0.5265, \"times_seen\": 27.0}, {\"site\": 1155, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.004429238171465174, \"epitope\": \"all\", \"reference_site\": \"1158\", \"IC90\": 0.0871758958988163, \"functional effect\": -0.2548, \"times_seen\": 19.0}, {\"site\": 1156, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1156, \"mutant\": \"L\", \"log2 fold change IC90\": 0.5566877630702904, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.12862028504700165, \"functional effect\": -0.3597, \"times_seen\": 28.0}, {\"site\": 1156, \"mutant\": \"N\", \"log2 fold change IC90\": -0.15568066651569815, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.07849919487857047, \"functional effect\": 0.152, \"times_seen\": 18.0}, {\"site\": 1156, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.02759854610114488, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.08913283970473637, \"functional effect\": 0.2068, \"times_seen\": 24.0}, {\"site\": 1156, \"mutant\": \"R\", \"log2 fold change IC90\": -2.8079879315219727, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.012486512549014395, \"functional effect\": 0.0721, \"times_seen\": 43.0}, {\"site\": 1156, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.22632943635934175, \"epitope\": \"all\", \"reference_site\": \"1159\", \"IC90\": 0.07474769478395836, \"functional effect\": 0.0425, \"times_seen\": 61.0}, {\"site\": 1157, \"mutant\": \"A\", \"log2 fold change IC90\": 0.048926699516214534, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.09046032775969318, \"functional effect\": -0.78, \"times_seen\": 36.0}, {\"site\": 1157, \"mutant\": \"I\", \"log2 fold change IC90\": 0.008372137925978433, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.08795287039095057, \"functional effect\": -0.7148, \"times_seen\": 5.0}, {\"site\": 1157, \"mutant\": \"N\", \"log2 fold change IC90\": -0.010379145995254664, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.08681710875289195, \"functional effect\": -0.2803, \"times_seen\": 8.0}, {\"site\": 1157, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": null, \"functional effect\": -2.9246, \"times_seen\": null}, {\"site\": 1157, \"mutant\": \"S\", \"log2 fold change IC90\": -0.002523240568821645, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.08729114330061039, \"functional effect\": -0.1738, \"times_seen\": 2.0}, {\"site\": 1157, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1160\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1158, \"mutant\": \"A\", \"log2 fold change IC90\": -0.5688329718668589, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.05895137861094253, \"functional effect\": 0.2119, \"times_seen\": 15.0}, {\"site\": 1158, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0028764905319082525, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08726977231265347, \"functional effect\": -0.1953, \"times_seen\": 1.0}, {\"site\": 1158, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0023745162214767307, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08758798865222973, \"functional effect\": 0.0086, \"times_seen\": 5.0}, {\"site\": 1158, \"mutant\": \"I\", \"log2 fold change IC90\": -0.013679553053673398, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.0866187270468505, \"functional effect\": -0.9118, \"times_seen\": 4.0}, {\"site\": 1158, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": null, \"functional effect\": -1.62, \"times_seen\": null}, {\"site\": 1158, \"mutant\": \"L\", \"log2 fold change IC90\": 0.010199040100791583, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08806431672224625, \"functional effect\": -0.2703, \"times_seen\": 9.0}, {\"site\": 1158, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0044662253590651655, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08717366094978549, \"functional effect\": 0.0661, \"times_seen\": 17.0}, {\"site\": 1158, \"mutant\": \"P\", \"log2 fold change IC90\": -0.012319680856299722, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.08670041162114263, \"functional effect\": -0.572, \"times_seen\": 8.0}, {\"site\": 1158, \"mutant\": \"R\", \"log2 fold change IC90\": 0.027073379609678226, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.0891003996805787, \"functional effect\": -0.1152, \"times_seen\": 6.0}, {\"site\": 1158, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1158, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1161\", \"IC90\": null, \"functional effect\": -0.0525, \"times_seen\": null}, {\"site\": 1159, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0104380631293, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.08807890826300768, \"functional effect\": -0.0636, \"times_seen\": 33.0}, {\"site\": 1159, \"mutant\": \"H\", \"log2 fold change IC90\": 0.016123488696331473, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.08842669769795082, \"functional effect\": 0.0107, \"times_seen\": 6.0}, {\"site\": 1159, \"mutant\": \"L\", \"log2 fold change IC90\": -0.7592085198651857, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.05166366544864569, \"functional effect\": -0.1481, \"times_seen\": 35.0}, {\"site\": 1159, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1159, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.5395650777092534, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.1271027730500374, \"functional effect\": 0.0636, \"times_seen\": 43.0}, {\"site\": 1159, \"mutant\": \"R\", \"log2 fold change IC90\": -0.42960295481053845, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.06492416565671257, \"functional effect\": 0.2868, \"times_seen\": 14.0}, {\"site\": 1159, \"mutant\": \"S\", \"log2 fold change IC90\": 0.10979431872976565, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.09435852341007583, \"functional effect\": -0.0167, \"times_seen\": 26.0}, {\"site\": 1159, \"mutant\": \"T\", \"log2 fold change IC90\": -0.1944992672925456, \"epitope\": \"all\", \"reference_site\": \"1162\", \"IC90\": 0.07641517978562336, \"functional effect\": -0.0225, \"times_seen\": 52.0}, {\"site\": 1160, \"mutant\": \"*\", \"log2 fold change IC90\": 0.07940991235714154, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.09239203192337724, \"functional effect\": -2.8361, \"times_seen\": 14.0}, {\"site\": 1160, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008850972271530526, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08690911843725573, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1160, \"mutant\": \"A\", \"log2 fold change IC90\": -1.3187956254427575, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.035053606847528465, \"functional effect\": -0.1275, \"times_seen\": 192.0}, {\"site\": 1160, \"mutant\": \"C\", \"log2 fold change IC90\": 0.025697828647260522, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08901548656545648, \"functional effect\": -1.0516, \"times_seen\": 42.0}, {\"site\": 1160, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1160, \"mutant\": \"E\", \"log2 fold change IC90\": -0.3419419262016969, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.06899140291590439, \"functional effect\": -0.0843, \"times_seen\": 153.0}, {\"site\": 1160, \"mutant\": \"F\", \"log2 fold change IC90\": -1.649706412928225, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.027868823718748062, \"functional effect\": -0.7344, \"times_seen\": 46.0}, {\"site\": 1160, \"mutant\": \"G\", \"log2 fold change IC90\": -0.10633218895853763, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.0812307708302701, \"functional effect\": -0.0435, \"times_seen\": 209.0}, {\"site\": 1160, \"mutant\": \"H\", \"log2 fold change IC90\": 0.017261607558726865, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08849648361725465, \"functional effect\": -0.3688, \"times_seen\": 136.0}, {\"site\": 1160, \"mutant\": \"I\", \"log2 fold change IC90\": -0.3597471197358153, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.06814516994266305, \"functional effect\": -0.2986, \"times_seen\": 68.0}, {\"site\": 1160, \"mutant\": \"K\", \"log2 fold change IC90\": -0.12949316773208364, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.0799371067101095, \"functional effect\": -0.2916, \"times_seen\": 72.0}, {\"site\": 1160, \"mutant\": \"L\", \"log2 fold change IC90\": -0.14324051699017581, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.0791790087757917, \"functional effect\": -0.4725, \"times_seen\": 103.0}, {\"site\": 1160, \"mutant\": \"M\", \"log2 fold change IC90\": -0.012948261674958342, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08666264456470657, \"functional effect\": -0.3362, \"times_seen\": 38.0}, {\"site\": 1160, \"mutant\": \"N\", \"log2 fold change IC90\": -0.025686930717769643, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08590080152636602, \"functional effect\": -0.074, \"times_seen\": 180.0}, {\"site\": 1160, \"mutant\": \"P\", \"log2 fold change IC90\": 0.4528146247786602, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.11968522411374223, \"functional effect\": -0.0814, \"times_seen\": 112.0}, {\"site\": 1160, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.06663994934565977, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08349666496107798, \"functional effect\": -0.204, \"times_seen\": 38.0}, {\"site\": 1160, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0484589411556331, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08455555762838926, \"functional effect\": -0.2112, \"times_seen\": 122.0}, {\"site\": 1160, \"mutant\": \"S\", \"log2 fold change IC90\": 0.029029311619663718, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.08922127935951285, \"functional effect\": -0.0991, \"times_seen\": 157.0}, {\"site\": 1160, \"mutant\": \"T\", \"log2 fold change IC90\": 0.19853158184943384, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.1003445325233625, \"functional effect\": -0.1426, \"times_seen\": 99.0}, {\"site\": 1160, \"mutant\": \"V\", \"log2 fold change IC90\": 0.42755312690594455, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.1176077844914938, \"functional effect\": -0.2857, \"times_seen\": 123.0}, {\"site\": 1160, \"mutant\": \"W\", \"log2 fold change IC90\": 0.1487007039182654, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.09693779238394301, \"functional effect\": -0.7356, \"times_seen\": 53.0}, {\"site\": 1160, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.31069771081679215, \"epitope\": \"all\", \"reference_site\": \"1163\", \"IC90\": 0.10845737359926089, \"functional effect\": -0.5144, \"times_seen\": 141.0}, {\"site\": 1161, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008539741303220723, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08692786926548607, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1161, \"mutant\": \"A\", \"log2 fold change IC90\": -0.010626776368145293, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08680220837030375, \"functional effect\": -0.0882, \"times_seen\": 10.0}, {\"site\": 1161, \"mutant\": \"E\", \"log2 fold change IC90\": -0.018177405332492937, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08634909865111565, \"functional effect\": 0.2839, \"times_seen\": 2.0}, {\"site\": 1161, \"mutant\": \"F\", \"log2 fold change IC90\": -0.037268424786044446, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.0852139778720871, \"functional effect\": -0.1568, \"times_seen\": 12.0}, {\"site\": 1161, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06536486938113426, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.09149693353068777, \"functional effect\": -0.149, \"times_seen\": 18.0}, {\"site\": 1161, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0022207553937815643, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.08730944726940154, \"functional effect\": -0.0091, \"times_seen\": 9.0}, {\"site\": 1161, \"mutant\": \"M\", \"log2 fold change IC90\": -0.2324534217469123, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.07443107650433164, \"functional effect\": 0.0547, \"times_seen\": 14.0}, {\"site\": 1161, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1161, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1164\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1162, \"mutant\": \"-\", \"log2 fold change IC90\": -0.01101495032591949, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08677885636361618, \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1162, \"mutant\": \"A\", \"log2 fold change IC90\": -0.7750412554505727, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.05109978666980096, \"functional effect\": 0.0419, \"times_seen\": 33.0}, {\"site\": 1162, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1162, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0013771836730813814, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08752746015351183, \"functional effect\": -0.0693, \"times_seen\": 73.0}, {\"site\": 1162, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0803734842859532, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08270560124736376, \"functional effect\": 0.0946, \"times_seen\": 173.0}, {\"site\": 1162, \"mutant\": \"H\", \"log2 fold change IC90\": -0.10505346517570359, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08130280113622029, \"functional effect\": -0.0328, \"times_seen\": 21.0}, {\"site\": 1162, \"mutant\": \"N\", \"log2 fold change IC90\": -0.07089083774717587, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08325100485873359, \"functional effect\": -0.0022, \"times_seen\": 56.0}, {\"site\": 1162, \"mutant\": \"V\", \"log2 fold change IC90\": -0.08084625041698015, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08267850335059818, \"functional effect\": -0.4093, \"times_seen\": 31.0}, {\"site\": 1162, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0010563890038704543, \"epitope\": \"all\", \"reference_site\": \"1165\", \"IC90\": 0.08750799989313696, \"functional effect\": -0.294, \"times_seen\": 17.0}, {\"site\": 1163, \"mutant\": \"-\", \"log2 fold change IC90\": -0.019861744282741487, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08624834535385242, \"functional effect\": -0.35, \"times_seen\": 1.0}, {\"site\": 1163, \"mutant\": \"F\", \"log2 fold change IC90\": -0.009922805184564534, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08684457433305214, \"functional effect\": 0.0174, \"times_seen\": 7.0}, {\"site\": 1163, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1163, \"mutant\": \"M\", \"log2 fold change IC90\": 0.001858372171584562, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08755665844593394, \"functional effect\": 0.0125, \"times_seen\": 8.0}, {\"site\": 1163, \"mutant\": \"P\", \"log2 fold change IC90\": -1.5753650453853496, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.029342534240404856, \"functional effect\": -0.0089, \"times_seen\": 41.0}, {\"site\": 1163, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": null, \"functional effect\": -0.1077, \"times_seen\": null}, {\"site\": 1163, \"mutant\": \"R\", \"log2 fold change IC90\": -0.021464595121819897, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": 0.08615257565733146, \"functional effect\": -0.9381, \"times_seen\": 2.0}, {\"site\": 1163, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1166\", \"IC90\": null, \"functional effect\": -3.2137, \"times_seen\": null}, {\"site\": 1164, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0036652859513168594, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08722207049106331, \"functional effect\": -2.5362, \"times_seen\": 3.0}, {\"site\": 1164, \"mutant\": \"-\", \"log2 fold change IC90\": -0.00819847692475823, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08694843417583262, \"functional effect\": -1.0601, \"times_seen\": 1.0}, {\"site\": 1164, \"mutant\": \"A\", \"log2 fold change IC90\": -0.41378750661876, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.06563980791724403, \"functional effect\": -0.085, \"times_seen\": 62.0}, {\"site\": 1164, \"mutant\": \"C\", \"log2 fold change IC90\": -0.009178803042000916, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08688937188960344, \"functional effect\": -1.4702, \"times_seen\": 22.0}, {\"site\": 1164, \"mutant\": \"D\", \"log2 fold change IC90\": -0.9004410183563741, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.046845728489330316, \"functional effect\": 0.0149, \"times_seen\": 94.0}, {\"site\": 1164, \"mutant\": \"E\", \"log2 fold change IC90\": 0.05355653984720393, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.09075109580610936, \"functional effect\": 0.1787, \"times_seen\": 50.0}, {\"site\": 1164, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0015217086825200764, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08735176263700202, \"functional effect\": -0.1835, \"times_seen\": 36.0}, {\"site\": 1164, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1164, \"mutant\": \"H\", \"log2 fold change IC90\": 0.02839969354732034, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08918235008329628, \"functional effect\": 0.0658, \"times_seen\": 25.0}, {\"site\": 1164, \"mutant\": \"I\", \"log2 fold change IC90\": 0.018031281204791492, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08854370883233087, \"functional effect\": -0.0695, \"times_seen\": 17.0}, {\"site\": 1164, \"mutant\": \"K\", \"log2 fold change IC90\": -1.1833227217112774, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.03850473324740839, \"functional effect\": 0.1964, \"times_seen\": 29.0}, {\"site\": 1164, \"mutant\": \"L\", \"log2 fold change IC90\": -0.11872195482925181, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08053615348463139, \"functional effect\": -0.2658, \"times_seen\": 61.0}, {\"site\": 1164, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0012101649578886264, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08737062790740652, \"functional effect\": -0.0558, \"times_seen\": 19.0}, {\"site\": 1164, \"mutant\": \"N\", \"log2 fold change IC90\": -0.01566355508983714, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08649969037285031, \"functional effect\": 0.0698, \"times_seen\": 25.0}, {\"site\": 1164, \"mutant\": \"P\", \"log2 fold change IC90\": 0.013684484426589878, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08827733079603681, \"functional effect\": 0.0568, \"times_seen\": 47.0}, {\"site\": 1164, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.013373860522110776, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08663708262629304, \"functional effect\": 0.1486, \"times_seen\": 23.0}, {\"site\": 1164, \"mutant\": \"R\", \"log2 fold change IC90\": 0.3167616458284748, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.10891420096873691, \"functional effect\": 0.0881, \"times_seen\": 144.0}, {\"site\": 1164, \"mutant\": \"S\", \"log2 fold change IC90\": -0.1640724530104108, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.0780439106440026, \"functional effect\": 0.0842, \"times_seen\": 74.0}, {\"site\": 1164, \"mutant\": \"T\", \"log2 fold change IC90\": -0.18486417159207602, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.0769272295450587, \"functional effect\": 0.066, \"times_seen\": 42.0}, {\"site\": 1164, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05455342544956264, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.08419911667812321, \"functional effect\": -0.1033, \"times_seen\": 91.0}, {\"site\": 1164, \"mutant\": \"W\", \"log2 fold change IC90\": -0.16573509928361352, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.0779540200773606, \"functional effect\": -0.3422, \"times_seen\": 31.0}, {\"site\": 1164, \"mutant\": \"Y\", \"log2 fold change IC90\": 1.1463607051838192, \"epitope\": \"all\", \"reference_site\": \"1167\", \"IC90\": 0.1935613805237421, \"functional effect\": -0.2037, \"times_seen\": 27.0}, {\"site\": 1165, \"mutant\": \"-\", \"log2 fold change IC90\": -0.02014739269219693, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.0862312701833263, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1165, \"mutant\": \"A\", \"log2 fold change IC90\": -0.13644431340247176, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07955288274955012, \"functional effect\": 0.0497, \"times_seen\": 61.0}, {\"site\": 1165, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1165, \"mutant\": \"E\", \"log2 fold change IC90\": -0.11543860614738095, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.08071964992221099, \"functional effect\": 0.1599, \"times_seen\": 32.0}, {\"site\": 1165, \"mutant\": \"G\", \"log2 fold change IC90\": -0.21372915073190002, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07540338932334148, \"functional effect\": -0.0215, \"times_seen\": 81.0}, {\"site\": 1165, \"mutant\": \"H\", \"log2 fold change IC90\": -0.17705019006252654, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07734501622132117, \"functional effect\": 0.0698, \"times_seen\": 112.0}, {\"site\": 1165, \"mutant\": \"N\", \"log2 fold change IC90\": -0.3306812017218682, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.06953201130436684, \"functional effect\": 0.1006, \"times_seen\": 106.0}, {\"site\": 1165, \"mutant\": \"V\", \"log2 fold change IC90\": -2.8068610583340035, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.012496269436281241, \"functional effect\": 0.0377, \"times_seen\": 34.0}, {\"site\": 1165, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.23958566326068098, \"epitope\": \"all\", \"reference_site\": \"1168\", \"IC90\": 0.07406402015979636, \"functional effect\": 0.0392, \"times_seen\": 92.0}, {\"site\": 1166, \"mutant\": \"-\", \"log2 fold change IC90\": -0.007303454604035164, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.08700239217211168, \"functional effect\": -0.2939, \"times_seen\": 1.0}, {\"site\": 1166, \"mutant\": \"F\", \"log2 fold change IC90\": 0.3667092463106986, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.1127509567168543, \"functional effect\": -0.195, \"times_seen\": 80.0}, {\"site\": 1166, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1166, \"mutant\": \"L\", \"log2 fold change IC90\": -0.029128618719282323, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.08569612112857841, \"functional effect\": -0.0663, \"times_seen\": 10.0}, {\"site\": 1166, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": null, \"functional effect\": -3.1213, \"times_seen\": null}, {\"site\": 1166, \"mutant\": \"N\", \"log2 fold change IC90\": -0.007454286302650404, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.08699329667218536, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1166, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": null, \"functional effect\": -0.2359, \"times_seen\": null}, {\"site\": 1166, \"mutant\": \"T\", \"log2 fold change IC90\": -0.18646520266256852, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.07684190689097267, \"functional effect\": 0.3117, \"times_seen\": 42.0}, {\"site\": 1166, \"mutant\": \"V\", \"log2 fold change IC90\": -0.13497573579969174, \"epitope\": \"all\", \"reference_site\": \"1169\", \"IC90\": 0.07963390407525545, \"functional effect\": 0.2283, \"times_seen\": 35.0}, {\"site\": 1167, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": null, \"functional effect\": -0.391, \"times_seen\": null}, {\"site\": 1167, \"mutant\": \"A\", \"log2 fold change IC90\": 0.029530610299544763, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.08925228680033494, \"functional effect\": -0.1606, \"times_seen\": 23.0}, {\"site\": 1167, \"mutant\": \"C\", \"log2 fold change IC90\": 0.00515934474054986, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.08775722268289753, \"functional effect\": -0.7865, \"times_seen\": 2.0}, {\"site\": 1167, \"mutant\": \"F\", \"log2 fold change IC90\": 0.5083448950587086, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.12438179339356047, \"functional effect\": -0.0314, \"times_seen\": 85.0}, {\"site\": 1167, \"mutant\": \"P\", \"log2 fold change IC90\": -0.11275112848593219, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.08087015604303419, \"functional effect\": 0.1262, \"times_seen\": 29.0}, {\"site\": 1167, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1167, \"mutant\": \"T\", \"log2 fold change IC90\": 1.9904974429494344, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.347479501218995, \"functional effect\": -0.2179, \"times_seen\": 2.0}, {\"site\": 1167, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.2267463195534353, \"epitope\": \"all\", \"reference_site\": \"1170\", \"IC90\": 0.1023262824674416, \"functional effect\": -0.0629, \"times_seen\": 59.0}, {\"site\": 1168, \"mutant\": \"-\", \"log2 fold change IC90\": -0.003543316066595676, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08722944482541564, \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1168, \"mutant\": \"A\", \"log2 fold change IC90\": 0.9705000405781746, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.17134813264033052, \"functional effect\": 0.0214, \"times_seen\": 21.0}, {\"site\": 1168, \"mutant\": \"C\", \"log2 fold change IC90\": 0.017077101334464856, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08848516652838209, \"functional effect\": -0.7442, \"times_seen\": 3.0}, {\"site\": 1168, \"mutant\": \"D\", \"log2 fold change IC90\": -0.028977167569218795, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08570511780285776, \"functional effect\": 0.0388, \"times_seen\": 148.0}, {\"site\": 1168, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1168, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": null, \"functional effect\": 0.1459, \"times_seen\": null}, {\"site\": 1168, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0024908608887659603, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.0872931024748851, \"functional effect\": 0.1299, \"times_seen\": 1.0}, {\"site\": 1168, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": null, \"functional effect\": -1.695, \"times_seen\": null}, {\"site\": 1168, \"mutant\": \"R\", \"log2 fold change IC90\": -0.10790961158884713, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.08114200277643431, \"functional effect\": -0.3251, \"times_seen\": 11.0}, {\"site\": 1168, \"mutant\": \"S\", \"log2 fold change IC90\": -0.13910463990812785, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.07940632257729086, \"functional effect\": 0.0186, \"times_seen\": 76.0}, {\"site\": 1168, \"mutant\": \"V\", \"log2 fold change IC90\": -0.13212486966033718, \"epitope\": \"all\", \"reference_site\": \"1171\", \"IC90\": 0.07979142181204316, \"functional effect\": 0.0614, \"times_seen\": 67.0}, {\"site\": 1169, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008207032835663798, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08694791852919269, \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1169, \"mutant\": \"F\", \"log2 fold change IC90\": -0.012170294488061001, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08670938963093289, \"functional effect\": 0.2852, \"times_seen\": 21.0}, {\"site\": 1169, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1169, \"mutant\": \"L\", \"log2 fold change IC90\": -0.025422138613809396, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08591656919786755, \"functional effect\": -0.0948, \"times_seen\": 8.0}, {\"site\": 1169, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05639334360693191, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08409180311970935, \"functional effect\": 0.1903, \"times_seen\": 17.0}, {\"site\": 1169, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1169, \"mutant\": \"T\", \"log2 fold change IC90\": -0.10153442427812508, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.08150135807107146, \"functional effect\": -0.392, \"times_seen\": 24.0}, {\"site\": 1169, \"mutant\": \"V\", \"log2 fold change IC90\": -0.36211604202592085, \"epitope\": \"all\", \"reference_site\": \"1172\", \"IC90\": 0.06803336658540798, \"functional effect\": -0.0292, \"times_seen\": 27.0}, {\"site\": 1170, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0011874727344326746, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08737200217525129, \"functional effect\": -0.4056, \"times_seen\": 1.0}, {\"site\": 1170, \"mutant\": \"D\", \"log2 fold change IC90\": 0.060931554147874246, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.09121620050670555, \"functional effect\": 0.186, \"times_seen\": 22.0}, {\"site\": 1170, \"mutant\": \"H\", \"log2 fold change IC90\": 0.011399681656877894, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08813763622802176, \"functional effect\": -0.059, \"times_seen\": 5.0}, {\"site\": 1170, \"mutant\": \"I\", \"log2 fold change IC90\": 0.01743133025326139, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08850689520442631, \"functional effect\": -0.6553, \"times_seen\": 21.0}, {\"site\": 1170, \"mutant\": \"K\", \"log2 fold change IC90\": 1.7510251344252958, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.29433427713101984, \"functional effect\": -0.4981, \"times_seen\": 21.0}, {\"site\": 1170, \"mutant\": \"M\", \"log2 fold change IC90\": -0.05926361662006869, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08392466697273102, \"functional effect\": -0.3446, \"times_seen\": 35.0}, {\"site\": 1170, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1170, \"mutant\": \"S\", \"log2 fold change IC90\": 0.018968765298161303, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08860126451256152, \"functional effect\": -0.1164, \"times_seen\": 45.0}, {\"site\": 1170, \"mutant\": \"T\", \"log2 fold change IC90\": -0.06510398969111865, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08358560669746119, \"functional effect\": -0.0951, \"times_seen\": 20.0}, {\"site\": 1170, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.0009006514699452412, \"epitope\": \"all\", \"reference_site\": \"1173\", \"IC90\": 0.08738937427309273, \"functional effect\": -0.4194, \"times_seen\": 1.0}, {\"site\": 1171, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": null, \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1171, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1171, \"mutant\": \"D\", \"log2 fold change IC90\": -0.018716729485341577, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.08631682471271555, \"functional effect\": 0.0621, \"times_seen\": 4.0}, {\"site\": 1171, \"mutant\": \"L\", \"log2 fold change IC90\": 0.009382189128593277, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.0880144689999689, \"functional effect\": 0.0907, \"times_seen\": 10.0}, {\"site\": 1171, \"mutant\": \"S\", \"log2 fold change IC90\": -0.7315871440569814, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.05266233095010417, \"functional effect\": 0.2213, \"times_seen\": 59.0}, {\"site\": 1171, \"mutant\": \"T\", \"log2 fold change IC90\": -0.22982196398373256, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.0745669617484907, \"functional effect\": 0.2596, \"times_seen\": 37.0}, {\"site\": 1171, \"mutant\": \"V\", \"log2 fold change IC90\": 0.5560332724477804, \"epitope\": \"all\", \"reference_site\": \"1174\", \"IC90\": 0.1285619486167265, \"functional effect\": 0.0478, \"times_seen\": 62.0}, {\"site\": 1172, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": null, \"functional effect\": -2.4665, \"times_seen\": null}, {\"site\": 1172, \"mutant\": \"A\", \"log2 fold change IC90\": 0.038082636156809443, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.08978292885106413, \"functional effect\": -0.4219, \"times_seen\": 19.0}, {\"site\": 1172, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": null, \"functional effect\": -2.0152, \"times_seen\": null}, {\"site\": 1172, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0014288320878377372, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.08753059368856743, \"functional effect\": -1.5856, \"times_seen\": 1.0}, {\"site\": 1172, \"mutant\": \"L\", \"log2 fold change IC90\": -0.034037054981436894, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.08540505531597396, \"functional effect\": -1.0889, \"times_seen\": 27.0}, {\"site\": 1172, \"mutant\": \"P\", \"log2 fold change IC90\": -0.025644680777697517, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.08590331720484078, \"functional effect\": -0.2426, \"times_seen\": 12.0}, {\"site\": 1172, \"mutant\": \"Q\", \"log2 fold change IC90\": 1.303185989270774, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.21578826616361083, \"functional effect\": -0.1875, \"times_seen\": 22.0}, {\"site\": 1172, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1172, \"mutant\": \"T\", \"log2 fold change IC90\": 0.045309418263246755, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.09023379993514051, \"functional effect\": -0.3201, \"times_seen\": 15.0}, {\"site\": 1172, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.044886903909855294, \"epitope\": \"all\", \"reference_site\": \"1175\", \"IC90\": 0.09020737751574136, \"functional effect\": -0.4335, \"times_seen\": 5.0}, {\"site\": 1173, \"mutant\": \"*\", \"log2 fold change IC90\": -0.014576106064302988, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08656491515091733, \"functional effect\": -2.882, \"times_seen\": 6.0}, {\"site\": 1173, \"mutant\": \"A\", \"log2 fold change IC90\": -0.057635574506083566, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.0840194271338308, \"functional effect\": -0.2905, \"times_seen\": 66.0}, {\"site\": 1173, \"mutant\": \"C\", \"log2 fold change IC90\": -0.6384366571842328, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.0561747526345002, \"functional effect\": -0.7802, \"times_seen\": 38.0}, {\"site\": 1173, \"mutant\": \"D\", \"log2 fold change IC90\": -0.07809332380085932, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08283641971056618, \"functional effect\": -0.9151, \"times_seen\": 28.0}, {\"site\": 1173, \"mutant\": \"E\", \"log2 fold change IC90\": -0.02718520586183042, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08581163768744464, \"functional effect\": -1.1258, \"times_seen\": 30.0}, {\"site\": 1173, \"mutant\": \"F\", \"log2 fold change IC90\": 0.31039182231718415, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.10843438028083847, \"functional effect\": -0.4019, \"times_seen\": 42.0}, {\"site\": 1173, \"mutant\": \"G\", \"log2 fold change IC90\": -0.07348468396892446, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08310146091965606, \"functional effect\": -0.6579, \"times_seen\": 15.0}, {\"site\": 1173, \"mutant\": \"H\", \"log2 fold change IC90\": -0.058575433369217084, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08396470961913273, \"functional effect\": -0.2005, \"times_seen\": 22.0}, {\"site\": 1173, \"mutant\": \"I\", \"log2 fold change IC90\": 0.05082374138186195, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.09057935492696736, \"functional effect\": -0.2854, \"times_seen\": 26.0}, {\"site\": 1173, \"mutant\": \"K\", \"log2 fold change IC90\": -0.05340755065349214, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08426601922427045, \"functional effect\": -0.2019, \"times_seen\": 21.0}, {\"site\": 1173, \"mutant\": \"L\", \"log2 fold change IC90\": -0.22100730931087553, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.07502394956855922, \"functional effect\": -0.3821, \"times_seen\": 81.0}, {\"site\": 1173, \"mutant\": \"M\", \"log2 fold change IC90\": 0.23645678341757015, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.10301734130317197, \"functional effect\": -0.03, \"times_seen\": 44.0}, {\"site\": 1173, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0070176179836637514, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08701963138951818, \"functional effect\": -0.3721, \"times_seen\": 13.0}, {\"site\": 1173, \"mutant\": \"P\", \"log2 fold change IC90\": -0.3147754576105743, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.07030284465608529, \"functional effect\": -0.5789, \"times_seen\": 39.0}, {\"site\": 1173, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.08199481908227892, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08261270694547192, \"functional effect\": -0.3196, \"times_seen\": 28.0}, {\"site\": 1173, \"mutant\": \"R\", \"log2 fold change IC90\": -1.6800127462979506, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.027289496513789698, \"functional effect\": -0.2285, \"times_seen\": 104.0}, {\"site\": 1173, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0959147426084103, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.09345509157378486, \"functional effect\": -0.7665, \"times_seen\": 73.0}, {\"site\": 1173, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02548053476898686, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.08591309161208158, \"functional effect\": -0.7113, \"times_seen\": 30.0}, {\"site\": 1173, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1173, \"mutant\": \"W\", \"log2 fold change IC90\": -0.008981152150191232, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.0869012766496687, \"functional effect\": 0.0842, \"times_seen\": 25.0}, {\"site\": 1173, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06229704818661701, \"epitope\": \"all\", \"reference_site\": \"1176\", \"IC90\": 0.0837483911328908, \"functional effect\": -0.3186, \"times_seen\": 24.0}, {\"site\": 1174, \"mutant\": \"A\", \"log2 fold change IC90\": -0.05916260784376934, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.08393054307574482, \"functional effect\": 0.1103, \"times_seen\": 22.0}, {\"site\": 1174, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": null, \"functional effect\": 0.2962, \"times_seen\": null}, {\"site\": 1174, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0014655834202099013, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.08735516095460721, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1174, \"mutant\": \"I\", \"log2 fold change IC90\": -0.06963310443640873, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.0833236142557238, \"functional effect\": -0.1009, \"times_seen\": 20.0}, {\"site\": 1174, \"mutant\": \"L\", \"log2 fold change IC90\": -1.1817793716378169, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.03854594644820877, \"functional effect\": 0.1073, \"times_seen\": 41.0}, {\"site\": 1174, \"mutant\": \"M\", \"log2 fold change IC90\": 0.8088364486777436, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.15318413391349156, \"functional effect\": 0.0916, \"times_seen\": 26.0}, {\"site\": 1174, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1177\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1175, \"mutant\": \"D\", \"log2 fold change IC90\": -0.0038615781393437007, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08721020391781568, \"functional effect\": -0.1074, \"times_seen\": 34.0}, {\"site\": 1175, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1175, \"mutant\": \"H\", \"log2 fold change IC90\": -0.014157239322063553, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08659005173706957, \"functional effect\": 0.0489, \"times_seen\": 29.0}, {\"site\": 1175, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0025707267477947256, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08759990167166136, \"functional effect\": 0.1337, \"times_seen\": 2.0}, {\"site\": 1175, \"mutant\": \"K\", \"log2 fold change IC90\": 0.03970540817444141, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08988397529037788, \"functional effect\": 0.008, \"times_seen\": 31.0}, {\"site\": 1175, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1175, \"mutant\": \"R\", \"log2 fold change IC90\": -0.035496091294187564, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08531872654624206, \"functional effect\": -0.031, \"times_seen\": 8.0}, {\"site\": 1175, \"mutant\": \"S\", \"log2 fold change IC90\": -0.045342131047302, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08473842961121397, \"functional effect\": 0.0274, \"times_seen\": 22.0}, {\"site\": 1175, \"mutant\": \"T\", \"log2 fold change IC90\": -0.028990639680536667, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.08570431747883654, \"functional effect\": 0.191, \"times_seen\": 23.0}, {\"site\": 1175, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.010754507069968762, \"epitope\": \"all\", \"reference_site\": \"1178\", \"IC90\": 0.0867945235749164, \"functional effect\": 0.1389, \"times_seen\": 35.0}, {\"site\": 1176, \"mutant\": \"F\", \"log2 fold change IC90\": -0.000547891849662986, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08741074484053386, \"functional effect\": 0.3638, \"times_seen\": 21.0}, {\"site\": 1176, \"mutant\": \"H\", \"log2 fold change IC90\": 0.011176054693919128, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08812397538921103, \"functional effect\": -0.878, \"times_seen\": 8.0}, {\"site\": 1176, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1176, \"mutant\": \"L\", \"log2 fold change IC90\": 0.02110067045836474, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.0887322895176399, \"functional effect\": -0.3533, \"times_seen\": 3.0}, {\"site\": 1176, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1176, \"mutant\": \"N\", \"log2 fold change IC90\": -0.004815340668802166, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08715256849657585, \"functional effect\": -0.3435, \"times_seen\": 1.0}, {\"site\": 1176, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0013293476895934275, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08752455802062414, \"functional effect\": -0.0605, \"times_seen\": 5.0}, {\"site\": 1176, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01499024295998444, \"epitope\": \"all\", \"reference_site\": \"1179\", \"IC90\": 0.08654006958117465, \"functional effect\": 0.2336, \"times_seen\": 34.0}, {\"site\": 1177, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": null, \"functional effect\": -3.1214, \"times_seen\": null}, {\"site\": 1177, \"mutant\": \"E\", \"log2 fold change IC90\": -0.036141451131413774, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08528056951063237, \"functional effect\": 0.2389, \"times_seen\": 16.0}, {\"site\": 1177, \"mutant\": \"H\", \"log2 fold change IC90\": -0.01203442439786085, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08671755612976957, \"functional effect\": -0.0602, \"times_seen\": 13.0}, {\"site\": 1177, \"mutant\": \"K\", \"log2 fold change IC90\": 0.635871179867944, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.1358770318299242, \"functional effect\": 0.0837, \"times_seen\": 86.0}, {\"site\": 1177, \"mutant\": \"L\", \"log2 fold change IC90\": -0.03411824600196733, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08540024908299351, \"functional effect\": 0.0438, \"times_seen\": 19.0}, {\"site\": 1177, \"mutant\": \"P\", \"log2 fold change IC90\": 0.011208599825815282, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08812596336218541, \"functional effect\": -1.8418, \"times_seen\": 6.0}, {\"site\": 1177, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1177, \"mutant\": \"R\", \"log2 fold change IC90\": -0.017703926813501986, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.0863774422385402, \"functional effect\": 0.1147, \"times_seen\": 35.0}, {\"site\": 1177, \"mutant\": \"S\", \"log2 fold change IC90\": 0.022168118264995616, \"epitope\": \"all\", \"reference_site\": \"1180\", \"IC90\": 0.08879796669423914, \"functional effect\": 0.0368, \"times_seen\": 11.0}, {\"site\": 1178, \"mutant\": \"E\", \"log2 fold change IC90\": -0.05327188904332578, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08427394342240142, \"functional effect\": -0.328, \"times_seen\": 35.0}, {\"site\": 1178, \"mutant\": \"I\", \"log2 fold change IC90\": -0.09020220087667845, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08214406387258469, \"functional effect\": -0.022, \"times_seen\": 16.0}, {\"site\": 1178, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1178, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": null, \"functional effect\": -0.1879, \"times_seen\": null}, {\"site\": 1178, \"mutant\": \"N\", \"log2 fold change IC90\": -0.5389390017443614, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.06018564892360181, \"functional effect\": -0.1419, \"times_seen\": 65.0}, {\"site\": 1178, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.004923851084477015, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08774289908572232, \"functional effect\": 0.0397, \"times_seen\": 32.0}, {\"site\": 1178, \"mutant\": \"R\", \"log2 fold change IC90\": 0.619928514036333, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.1343837731256781, \"functional effect\": -0.0624, \"times_seen\": 63.0}, {\"site\": 1178, \"mutant\": \"T\", \"log2 fold change IC90\": 0.019705868918571696, \"epitope\": \"all\", \"reference_site\": \"1181\", \"IC90\": 0.08864654435170934, \"functional effect\": -0.0284, \"times_seen\": 23.0}, {\"site\": 1179, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": null, \"functional effect\": -2.8676, \"times_seen\": null}, {\"site\": 1179, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1179, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004666992335602881, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08716153061445266, \"functional effect\": 0.2404, \"times_seen\": 21.0}, {\"site\": 1179, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1179, \"mutant\": \"G\", \"log2 fold change IC90\": -0.06906507290011986, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08335642767657192, \"functional effect\": -0.1308, \"times_seen\": 14.0}, {\"site\": 1179, \"mutant\": \"I\", \"log2 fold change IC90\": -0.010475002155281441, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.0868113406051029, \"functional effect\": -2.2387, \"times_seen\": 2.0}, {\"site\": 1179, \"mutant\": \"K\", \"log2 fold change IC90\": -0.12889970276816085, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.07996999628797728, \"functional effect\": 0.0599, \"times_seen\": 64.0}, {\"site\": 1179, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.041179197208323984, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.0849832976572649, \"functional effect\": 0.1102, \"times_seen\": 43.0}, {\"site\": 1179, \"mutant\": \"V\", \"log2 fold change IC90\": 0.003166125086582872, \"epitope\": \"all\", \"reference_site\": \"1182\", \"IC90\": 0.08763606149647821, \"functional effect\": -2.2533, \"times_seen\": 1.0}, {\"site\": 1180, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1180, \"mutant\": \"F\", \"log2 fold change IC90\": -0.004426649631493526, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08717605231336487, \"functional effect\": -1.1997, \"times_seen\": 1.0}, {\"site\": 1180, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1180, \"mutant\": \"L\", \"log2 fold change IC90\": 0.016901786885727927, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08847441457786831, \"functional effect\": 0.0006, \"times_seen\": 9.0}, {\"site\": 1180, \"mutant\": \"M\", \"log2 fold change IC90\": -0.07026755642286021, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08328697920213185, \"functional effect\": 0.1599, \"times_seen\": 19.0}, {\"site\": 1180, \"mutant\": \"N\", \"log2 fold change IC90\": -0.006221581759142999, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08706765948357831, \"functional effect\": -3.0473, \"times_seen\": 1.0}, {\"site\": 1180, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": null, \"functional effect\": -3.2623, \"times_seen\": null}, {\"site\": 1180, \"mutant\": \"T\", \"log2 fold change IC90\": -0.006230757900093581, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08706710569878512, \"functional effect\": -1.5486, \"times_seen\": 2.0}, {\"site\": 1180, \"mutant\": \"V\", \"log2 fold change IC90\": -0.02990592270767876, \"epitope\": \"all\", \"reference_site\": \"1183\", \"IC90\": 0.08564996168858134, \"functional effect\": 0.3074, \"times_seen\": 31.0}, {\"site\": 1181, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1181, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1181, \"mutant\": \"E\", \"log2 fold change IC90\": -0.009692667459833286, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08685842882506467, \"functional effect\": 0.0134, \"times_seen\": 36.0}, {\"site\": 1181, \"mutant\": \"G\", \"log2 fold change IC90\": -0.371505623955387, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.06759201857546628, \"functional effect\": 0.2674, \"times_seen\": 96.0}, {\"site\": 1181, \"mutant\": \"H\", \"log2 fold change IC90\": 0.004651961298117892, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08772636464873598, \"functional effect\": 0.0345, \"times_seen\": 13.0}, {\"site\": 1181, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": null, \"functional effect\": -2.8217, \"times_seen\": null}, {\"site\": 1181, \"mutant\": \"M\", \"log2 fold change IC90\": 0.022749741826642307, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08883377287666276, \"functional effect\": -0.0548, \"times_seen\": 17.0}, {\"site\": 1181, \"mutant\": \"N\", \"log2 fold change IC90\": -0.10501394831184623, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08130502813197088, \"functional effect\": 0.0246, \"times_seen\": 105.0}, {\"site\": 1181, \"mutant\": \"T\", \"log2 fold change IC90\": -0.029179513775429867, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08569309801430851, \"functional effect\": 0.029, \"times_seen\": 13.0}, {\"site\": 1181, \"mutant\": \"V\", \"log2 fold change IC90\": -0.007099903007942405, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.08701466831133241, \"functional effect\": -1.9232, \"times_seen\": 1.0}, {\"site\": 1181, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.26315522265269164, \"epitope\": \"all\", \"reference_site\": \"1184\", \"IC90\": 0.0728638537593449, \"functional effect\": 0.073, \"times_seen\": 95.0}, {\"site\": 1182, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": null, \"functional effect\": -3.1155, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": null, \"functional effect\": -1.1672, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"C\", \"log2 fold change IC90\": -0.0394854321624317, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08508312905884363, \"functional effect\": 0.1659, \"times_seen\": 59.0}, {\"site\": 1182, \"mutant\": \"G\", \"log2 fold change IC90\": -0.21764025772460435, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.0751992496206137, \"functional effect\": -0.3745, \"times_seen\": 14.0}, {\"site\": 1182, \"mutant\": \"H\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"I\", \"log2 fold change IC90\": -0.01441201273602813, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08657476167599404, \"functional effect\": 0.091, \"times_seen\": 2.0}, {\"site\": 1182, \"mutant\": \"K\", \"log2 fold change IC90\": -0.021695707654444233, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08613877555082479, \"functional effect\": 0.157, \"times_seen\": 9.0}, {\"site\": 1182, \"mutant\": \"L\", \"log2 fold change IC90\": -0.053109399069145344, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08428343568631518, \"functional effect\": 0.0256, \"times_seen\": 41.0}, {\"site\": 1182, \"mutant\": \"N\", \"log2 fold change IC90\": -0.07772757531117312, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08285742285767193, \"functional effect\": 0.0854, \"times_seen\": 20.0}, {\"site\": 1182, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1182, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07529534643201127, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08299722938918397, \"functional effect\": -0.0833, \"times_seen\": 84.0}, {\"site\": 1182, \"mutant\": \"T\", \"log2 fold change IC90\": -0.020940381522100506, \"epitope\": \"all\", \"reference_site\": \"1185\", \"IC90\": 0.08618388550214028, \"functional effect\": -0.1672, \"times_seen\": 1.0}, {\"site\": 1183, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": null, \"functional effect\": -1.4169, \"times_seen\": null}, {\"site\": 1183, \"mutant\": \"F\", \"log2 fold change IC90\": -0.04122917559994341, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08498035368446183, \"functional effect\": 0.4069, \"times_seen\": 15.0}, {\"site\": 1183, \"mutant\": \"I\", \"log2 fold change IC90\": -0.014047119495535863, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08659666134279063, \"functional effect\": -0.178, \"times_seen\": 15.0}, {\"site\": 1183, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1183, \"mutant\": \"M\", \"log2 fold change IC90\": -0.015510751374113273, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08650885251295302, \"functional effect\": -0.0126, \"times_seen\": 4.0}, {\"site\": 1183, \"mutant\": \"P\", \"log2 fold change IC90\": -0.0007195208547778508, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08740034671312624, \"functional effect\": -2.4142, \"times_seen\": 1.0}, {\"site\": 1183, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.01316607894837828, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.08824561568684583, \"functional effect\": -2.1079, \"times_seen\": 1.0}, {\"site\": 1183, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004525842759320766, \"epitope\": \"all\", \"reference_site\": \"1186\", \"IC90\": 0.0871700586918516, \"functional effect\": -2.0339, \"times_seen\": 1.0}, {\"site\": 1184, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1184, \"mutant\": \"D\", \"log2 fold change IC90\": -0.6020880622997247, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.057608051484088214, \"functional effect\": 0.3598, \"times_seen\": 44.0}, {\"site\": 1184, \"mutant\": \"H\", \"log2 fold change IC90\": 0.016314211440223957, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08843838838569545, \"functional effect\": 0.0092, \"times_seen\": 5.0}, {\"site\": 1184, \"mutant\": \"I\", \"log2 fold change IC90\": 0.019330885929356726, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08862350647769575, \"functional effect\": -0.3623, \"times_seen\": 23.0}, {\"site\": 1184, \"mutant\": \"K\", \"log2 fold change IC90\": 0.000843032407881658, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08749505950867756, \"functional effect\": -0.2011, \"times_seen\": 36.0}, {\"site\": 1184, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1184, \"mutant\": \"S\", \"log2 fold change IC90\": 0.08291802678401497, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.09261696942178188, \"functional effect\": -0.1086, \"times_seen\": 28.0}, {\"site\": 1184, \"mutant\": \"T\", \"log2 fold change IC90\": -0.008290832869889783, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08694286824016217, \"functional effect\": -0.02, \"times_seen\": 22.0}, {\"site\": 1184, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.054773844951996185, \"epitope\": \"all\", \"reference_site\": \"1187\", \"IC90\": 0.08418625345395682, \"functional effect\": -0.1487, \"times_seen\": 36.0}, {\"site\": 1185, \"mutant\": \"*\", \"log2 fold change IC90\": -0.8492753090785585, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.048536941938938795, \"functional effect\": -2.5368, \"times_seen\": 2.0}, {\"site\": 1185, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1185, \"mutant\": \"A\", \"log2 fold change IC90\": -0.0505809856661852, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08443127719822785, \"functional effect\": -0.0764, \"times_seen\": 45.0}, {\"site\": 1185, \"mutant\": \"D\", \"log2 fold change IC90\": -0.534387531229987, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.06037582478269334, \"functional effect\": 0.1741, \"times_seen\": 70.0}, {\"site\": 1185, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1185, \"mutant\": \"G\", \"log2 fold change IC90\": 0.08771683789579435, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.09292555254917968, \"functional effect\": 0.0898, \"times_seen\": 45.0}, {\"site\": 1185, \"mutant\": \"K\", \"log2 fold change IC90\": -0.05925957953419519, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08392490181900963, \"functional effect\": 0.0326, \"times_seen\": 130.0}, {\"site\": 1185, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.14015420372422085, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.07934857531110506, \"functional effect\": -0.1775, \"times_seen\": 21.0}, {\"site\": 1185, \"mutant\": \"R\", \"log2 fold change IC90\": -0.05328398372054808, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08427323692390894, \"functional effect\": -0.3296, \"times_seen\": 17.0}, {\"site\": 1185, \"mutant\": \"S\", \"log2 fold change IC90\": 0.003937361230436327, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08768292252050801, \"functional effect\": 0.2637, \"times_seen\": 12.0}, {\"site\": 1185, \"mutant\": \"V\", \"log2 fold change IC90\": -0.002897931287749389, \"epitope\": \"all\", \"reference_site\": \"1188\", \"IC90\": 0.08726847535388983, \"functional effect\": 0.1173, \"times_seen\": 33.0}, {\"site\": 1186, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1186, \"mutant\": \"A\", \"log2 fold change IC90\": -0.05027009863897105, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08444947329400104, \"functional effect\": 0.2116, \"times_seen\": 18.0}, {\"site\": 1186, \"mutant\": \"F\", \"log2 fold change IC90\": -0.16105157129980538, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.07820749921971444, \"functional effect\": 0.1328, \"times_seen\": 35.0}, {\"site\": 1186, \"mutant\": \"G\", \"log2 fold change IC90\": -0.017647699058380397, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08638080878807333, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1186, \"mutant\": \"I\", \"log2 fold change IC90\": -2.0570882441476877, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.02101282712821758, \"functional effect\": -0.1789, \"times_seen\": 38.0}, {\"site\": 1186, \"mutant\": \"L\", \"log2 fold change IC90\": -0.01766759990919212, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08637961724052966, \"functional effect\": -0.061, \"times_seen\": 1.0}, {\"site\": 1186, \"mutant\": \"M\", \"log2 fold change IC90\": -0.031381593846987264, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.08556239879071882, \"functional effect\": -0.0626, \"times_seen\": 16.0}, {\"site\": 1186, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": null, \"functional effect\": -2.9313, \"times_seen\": null}, {\"site\": 1186, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1189\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"D\", \"log2 fold change IC90\": -0.014209249174534158, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.08658693018018314, \"functional effect\": -0.0999, \"times_seen\": 3.0}, {\"site\": 1187, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": null, \"functional effect\": -0.126, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": null, \"functional effect\": -3.2974, \"times_seen\": null}, {\"site\": 1187, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07471108575906125, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.08303084830112477, \"functional effect\": 0.2268, \"times_seen\": 49.0}, {\"site\": 1187, \"mutant\": \"T\", \"log2 fold change IC90\": -0.05712738996692528, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.08404902791121975, \"functional effect\": -0.0464, \"times_seen\": 57.0}, {\"site\": 1187, \"mutant\": \"V\", \"log2 fold change IC90\": 0.053970956338666234, \"epitope\": \"all\", \"reference_site\": \"1190\", \"IC90\": 0.0907771679500891, \"functional effect\": -0.6084, \"times_seen\": 42.0}, {\"site\": 1188, \"mutant\": \"*\", \"log2 fold change IC90\": 0.018662697121965013, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08858246972203115, \"functional effect\": -2.9248, \"times_seen\": 4.0}, {\"site\": 1188, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": null, \"functional effect\": -1.1109, \"times_seen\": null}, {\"site\": 1188, \"mutant\": \"A\", \"log2 fold change IC90\": -0.061518949605222153, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08379357190807593, \"functional effect\": -0.0125, \"times_seen\": 72.0}, {\"site\": 1188, \"mutant\": \"C\", \"log2 fold change IC90\": -0.012893831101730957, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08666591426916437, \"functional effect\": 0.0765, \"times_seen\": 35.0}, {\"site\": 1188, \"mutant\": \"D\", \"log2 fold change IC90\": -2.5196643566374277, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.015248783642339291, \"functional effect\": -0.254, \"times_seen\": 38.0}, {\"site\": 1188, \"mutant\": \"E\", \"log2 fold change IC90\": 0.009282243115841774, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08800837180666533, \"functional effect\": -0.1586, \"times_seen\": 53.0}, {\"site\": 1188, \"mutant\": \"F\", \"log2 fold change IC90\": 1.8058932382554393, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.3057438897685715, \"functional effect\": -0.0813, \"times_seen\": 44.0}, {\"site\": 1188, \"mutant\": \"G\", \"log2 fold change IC90\": -0.15371344308894272, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.0786063074588537, \"functional effect\": -0.3656, \"times_seen\": 101.0}, {\"site\": 1188, \"mutant\": \"H\", \"log2 fold change IC90\": -0.04810947991337858, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08457604183915116, \"functional effect\": 0.0095, \"times_seen\": 23.0}, {\"site\": 1188, \"mutant\": \"I\", \"log2 fold change IC90\": 0.00023899220760487117, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08745843397843515, \"functional effect\": 0.0895, \"times_seen\": 30.0}, {\"site\": 1188, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1188, \"mutant\": \"L\", \"log2 fold change IC90\": 0.42001822818902734, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.11699514452237804, \"functional effect\": -0.0082, \"times_seen\": 94.0}, {\"site\": 1188, \"mutant\": \"M\", \"log2 fold change IC90\": -0.008754109781706413, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08691495370802878, \"functional effect\": 0.0308, \"times_seen\": 57.0}, {\"site\": 1188, \"mutant\": \"N\", \"log2 fold change IC90\": -0.08717910305545713, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08231637326340147, \"functional effect\": 0.0363, \"times_seen\": 102.0}, {\"site\": 1188, \"mutant\": \"P\", \"log2 fold change IC90\": 0.07075110409276478, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.09183917153594616, \"functional effect\": -2.8372, \"times_seen\": 6.0}, {\"site\": 1188, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.1389529404842157, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.09628502686064651, \"functional effect\": 0.0239, \"times_seen\": 43.0}, {\"site\": 1188, \"mutant\": \"R\", \"log2 fold change IC90\": 0.037670071258801584, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08975725745965796, \"functional effect\": -0.077, \"times_seen\": 153.0}, {\"site\": 1188, \"mutant\": \"S\", \"log2 fold change IC90\": -0.4189489792786585, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.06540539057034243, \"functional effect\": 0.0966, \"times_seen\": 80.0}, {\"site\": 1188, \"mutant\": \"T\", \"log2 fold change IC90\": -0.09609228410678813, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08180937842201397, \"functional effect\": 0.1724, \"times_seen\": 74.0}, {\"site\": 1188, \"mutant\": \"V\", \"log2 fold change IC90\": -0.6213442826157817, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.05684424284337814, \"functional effect\": 0.0846, \"times_seen\": 94.0}, {\"site\": 1188, \"mutant\": \"W\", \"log2 fold change IC90\": -0.0928102689332264, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.08199570003049479, \"functional effect\": -0.0432, \"times_seen\": 39.0}, {\"site\": 1188, \"mutant\": \"Y\", \"log2 fold change IC90\": 1.141694119537255, \"epitope\": \"all\", \"reference_site\": \"1191\", \"IC90\": 0.19293629245265298, \"functional effect\": -0.0513, \"times_seen\": 22.0}, {\"site\": 1189, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": null, \"functional effect\": -1.1747, \"times_seen\": null}, {\"site\": 1189, \"mutant\": \"D\", \"log2 fold change IC90\": -0.25289209608477414, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.07338404490224958, \"functional effect\": -0.0737, \"times_seen\": 84.0}, {\"site\": 1189, \"mutant\": \"H\", \"log2 fold change IC90\": 1.3021839360692606, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.2156384380708525, \"functional effect\": -0.1333, \"times_seen\": 26.0}, {\"site\": 1189, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0756865099707768, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.08297472907679235, \"functional effect\": -0.2161, \"times_seen\": 28.0}, {\"site\": 1189, \"mutant\": \"K\", \"log2 fold change IC90\": -0.8581739505297067, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.04823848416943389, \"functional effect\": -0.2615, \"times_seen\": 42.0}, {\"site\": 1189, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1189, \"mutant\": \"S\", \"log2 fold change IC90\": 0.5578110590494215, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.12872046901225587, \"functional effect\": -0.1757, \"times_seen\": 71.0}, {\"site\": 1189, \"mutant\": \"T\", \"log2 fold change IC90\": -0.3434382778929665, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.06891988268428777, \"functional effect\": -0.0432, \"times_seen\": 71.0}, {\"site\": 1189, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.07845903810097322, \"epitope\": \"all\", \"reference_site\": \"1192\", \"IC90\": 0.0828154238500451, \"functional effect\": -0.1824, \"times_seen\": 31.0}, {\"site\": 1190, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"M\", \"log2 fold change IC90\": 0.011308946188065775, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": 0.08813209315894799, \"functional effect\": 0.1436, \"times_seen\": 11.0}, {\"site\": 1190, \"mutant\": \"P\", \"log2 fold change IC90\": -0.001456583863454378, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": 0.0873557058793201, \"functional effect\": -3.0572, \"times_seen\": 7.0}, {\"site\": 1190, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -2.8743, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -3.1097, \"times_seen\": null}, {\"site\": 1190, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1193\", \"IC90\": null, \"functional effect\": -1.4736, \"times_seen\": null}, {\"site\": 1191, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1191, \"mutant\": \"D\", \"log2 fold change IC90\": -0.004596119263758318, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08716581257077932, \"functional effect\": -1.2563, \"times_seen\": 2.0}, {\"site\": 1191, \"mutant\": \"H\", \"log2 fold change IC90\": -0.02615174808806744, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08587312987569612, \"functional effect\": -1.0998, \"times_seen\": 11.0}, {\"site\": 1191, \"mutant\": \"K\", \"log2 fold change IC90\": -0.06460857247499552, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08361431467677129, \"functional effect\": -1.1808, \"times_seen\": 25.0}, {\"site\": 1191, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1191, \"mutant\": \"S\", \"log2 fold change IC90\": -0.022183801953095397, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08610963790725638, \"functional effect\": -0.4681, \"times_seen\": 14.0}, {\"site\": 1191, \"mutant\": \"T\", \"log2 fold change IC90\": -0.003932421317532364, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08720592158776481, \"functional effect\": -0.7439, \"times_seen\": 1.0}, {\"site\": 1191, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.016525911440595866, \"epitope\": \"all\", \"reference_site\": \"1194\", \"IC90\": 0.08845136672141209, \"functional effect\": -1.0239, \"times_seen\": 10.0}, {\"site\": 1192, \"mutant\": \"*\", \"log2 fold change IC90\": -0.008058289581234048, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08695688340584533, \"functional effect\": -2.6467, \"times_seen\": 2.0}, {\"site\": 1192, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1192, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02651118490707283, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08585173788426928, \"functional effect\": -0.1746, \"times_seen\": 8.0}, {\"site\": 1192, \"mutant\": \"D\", \"log2 fold change IC90\": -0.19187624136108097, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.07655423988932719, \"functional effect\": -0.0335, \"times_seen\": 49.0}, {\"site\": 1192, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1192, \"mutant\": \"G\", \"log2 fold change IC90\": -0.4399179472349785, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.06446162584892628, \"functional effect\": 0.0492, \"times_seen\": 62.0}, {\"site\": 1192, \"mutant\": \"K\", \"log2 fold change IC90\": -0.06901796575908281, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08335914949025512, \"functional effect\": -0.2683, \"times_seen\": 79.0}, {\"site\": 1192, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.08042515968050644, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.09245707254023303, \"functional effect\": -0.1986, \"times_seen\": 25.0}, {\"site\": 1192, \"mutant\": \"S\", \"log2 fold change IC90\": -0.04064906517143479, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08501453131780055, \"functional effect\": -0.1909, \"times_seen\": 9.0}, {\"site\": 1192, \"mutant\": \"V\", \"log2 fold change IC90\": 0.006649112546426423, \"epitope\": \"all\", \"reference_site\": \"1195\", \"IC90\": 0.08784789008414531, \"functional effect\": 0.0115, \"times_seen\": 14.0}, {\"site\": 1193, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -2.8134, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -0.9579, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"F\", \"log2 fold change IC90\": -3.841790484205503, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.006098676259836818, \"functional effect\": -1.122, \"times_seen\": 36.0}, {\"site\": 1193, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": null, \"functional effect\": -3.2983, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1193, \"mutant\": \"T\", \"log2 fold change IC90\": -2.8378191269708952, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.012230974855177495, \"functional effect\": -0.0384, \"times_seen\": 29.0}, {\"site\": 1193, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.3819665504725327, \"epitope\": \"all\", \"reference_site\": \"1196\", \"IC90\": 0.06710368402324852, \"functional effect\": -1.4316, \"times_seen\": 26.0}, {\"site\": 1194, \"mutant\": \"-\", \"log2 fold change IC90\": 0.027523058284464906, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08912817602513251, \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1194, \"mutant\": \"F\", \"log2 fold change IC90\": -0.19178955115411292, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.07655884010081114, \"functional effect\": -0.2202, \"times_seen\": 30.0}, {\"site\": 1194, \"mutant\": \"I\", \"log2 fold change IC90\": -0.007506858581516407, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08699012666577738, \"functional effect\": -0.066, \"times_seen\": 12.0}, {\"site\": 1194, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1194, \"mutant\": \"M\", \"log2 fold change IC90\": -0.12821907046862613, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08000773330268239, \"functional effect\": 0.0823, \"times_seen\": 35.0}, {\"site\": 1194, \"mutant\": \"P\", \"log2 fold change IC90\": 0.2312642783533991, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.10264723079849938, \"functional effect\": -2.5545, \"times_seen\": 25.0}, {\"site\": 1194, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": null, \"functional effect\": -0.7933, \"times_seen\": null}, {\"site\": 1194, \"mutant\": \"R\", \"log2 fold change IC90\": -0.009924941720880194, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08684444572205381, \"functional effect\": -1.8685, \"times_seen\": 2.0}, {\"site\": 1194, \"mutant\": \"S\", \"log2 fold change IC90\": 0.031025414967851158, \"epitope\": \"all\", \"reference_site\": \"1197\", \"IC90\": 0.08934481077239688, \"functional effect\": -0.832, \"times_seen\": 8.0}, {\"site\": 1195, \"mutant\": \"-\", \"log2 fold change IC90\": 0.026559740353932517, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08906868312526768, \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1195, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": null, \"functional effect\": -2.2422, \"times_seen\": null}, {\"site\": 1195, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1195, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": null, \"functional effect\": -2.8804, \"times_seen\": null}, {\"site\": 1195, \"mutant\": \"N\", \"log2 fold change IC90\": 0.0018161960904257127, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08755409883170472, \"functional effect\": -0.4286, \"times_seen\": 4.0}, {\"site\": 1195, \"mutant\": \"S\", \"log2 fold change IC90\": -0.05134228668734333, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08438673510217523, \"functional effect\": -0.5658, \"times_seen\": 8.0}, {\"site\": 1195, \"mutant\": \"T\", \"log2 fold change IC90\": -0.044123735851585466, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08481002374680041, \"functional effect\": -0.3756, \"times_seen\": 17.0}, {\"site\": 1195, \"mutant\": \"V\", \"log2 fold change IC90\": -0.021797347230829867, \"epitope\": \"all\", \"reference_site\": \"1198\", \"IC90\": 0.08613270718570772, \"functional effect\": 0.0335, \"times_seen\": 32.0}, {\"site\": 1196, \"mutant\": \"-\", \"log2 fold change IC90\": 0.02607393123683222, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08903869543380936, \"functional effect\": -0.8924, \"times_seen\": 1.0}, {\"site\": 1196, \"mutant\": \"D\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1196, \"mutant\": \"E\", \"log2 fold change IC90\": -0.03770404300288012, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08518825160538415, \"functional effect\": -0.3481, \"times_seen\": 24.0}, {\"site\": 1196, \"mutant\": \"G\", \"log2 fold change IC90\": 0.09265503079011315, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.09324417189933822, \"functional effect\": -0.5742, \"times_seen\": 98.0}, {\"site\": 1196, \"mutant\": \"H\", \"log2 fold change IC90\": -0.061767966289230966, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08377910994893688, \"functional effect\": -0.7052, \"times_seen\": 45.0}, {\"site\": 1196, \"mutant\": \"N\", \"log2 fold change IC90\": -0.011476873199788068, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08675107591034588, \"functional effect\": -0.3864, \"times_seen\": 124.0}, {\"site\": 1196, \"mutant\": \"S\", \"log2 fold change IC90\": -0.5864110185878076, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.05823746285313703, \"functional effect\": -0.4627, \"times_seen\": 21.0}, {\"site\": 1196, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0856963737905964, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.09279550335130361, \"functional effect\": -0.6228, \"times_seen\": 14.0}, {\"site\": 1196, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007634881688111555, \"epitope\": \"all\", \"reference_site\": \"1199\", \"IC90\": 0.08698240760400286, \"functional effect\": -0.6752, \"times_seen\": 80.0}, {\"site\": 1197, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1197, \"mutant\": \"F\", \"log2 fold change IC90\": -0.8840810662972166, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.04737997565871544, \"functional effect\": -0.6132, \"times_seen\": 115.0}, {\"site\": 1197, \"mutant\": \"H\", \"log2 fold change IC90\": 0.0009276169279710593, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.08750018945254218, \"functional effect\": -1.243, \"times_seen\": 2.0}, {\"site\": 1197, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06493505740750594, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.09146967855377387, \"functional effect\": -0.2187, \"times_seen\": 119.0}, {\"site\": 1197, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1197, \"mutant\": \"P\", \"log2 fold change IC90\": -0.055121024794066845, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.08416599674491657, \"functional effect\": -1.2615, \"times_seen\": 17.0}, {\"site\": 1197, \"mutant\": \"R\", \"log2 fold change IC90\": -0.00728033327811772, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.08700378652554577, \"functional effect\": -0.891, \"times_seen\": 2.0}, {\"site\": 1197, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03516042990339252, \"epitope\": \"all\", \"reference_site\": \"1200\", \"IC90\": 0.08533857934491498, \"functional effect\": -0.4283, \"times_seen\": 17.0}, {\"site\": 1198, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": null, \"functional effect\": -2.949, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"E\", \"log2 fold change IC90\": 0.05713183177335194, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.09097627439496578, \"functional effect\": 0.1791, \"times_seen\": 14.0}, {\"site\": 1198, \"mutant\": \"H\", \"log2 fold change IC90\": 0.18200899434545903, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.09920188387064194, \"functional effect\": -0.1289, \"times_seen\": 77.0}, {\"site\": 1198, \"mutant\": \"K\", \"log2 fold change IC90\": 0.10707017523600988, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.09418052069877193, \"functional effect\": -0.0713, \"times_seen\": 48.0}, {\"site\": 1198, \"mutant\": \"L\", \"log2 fold change IC90\": -0.08335149250565545, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.08253505659010994, \"functional effect\": -0.2985, \"times_seen\": 86.0}, {\"site\": 1198, \"mutant\": \"N\", \"log2 fold change IC90\": -0.040134372707647394, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.08504486631131854, \"functional effect\": -0.1313, \"times_seen\": 14.0}, {\"site\": 1198, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1198, \"mutant\": \"R\", \"log2 fold change IC90\": -0.15106671770627803, \"epitope\": \"all\", \"reference_site\": \"1201\", \"IC90\": 0.07875064861244413, \"functional effect\": -0.0902, \"times_seen\": 72.0}, {\"site\": 1199, \"mutant\": \"*\", \"log2 fold change IC90\": -8.256368277857385e-05, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08743894292872251, \"functional effect\": -3.0098, \"times_seen\": 1.0}, {\"site\": 1199, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1199, \"mutant\": \"A\", \"log2 fold change IC90\": 0.04030095536060333, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08992108722134075, \"functional effect\": -0.2665, \"times_seen\": 11.0}, {\"site\": 1199, \"mutant\": \"D\", \"log2 fold change IC90\": -0.1914971755562407, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.07657435703566039, \"functional effect\": -0.1355, \"times_seen\": 30.0}, {\"site\": 1199, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1199, \"mutant\": \"G\", \"log2 fold change IC90\": -0.06318818380499351, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08369667671816346, \"functional effect\": -0.5713, \"times_seen\": 54.0}, {\"site\": 1199, \"mutant\": \"K\", \"log2 fold change IC90\": 0.5846665796251127, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.1311390190599678, \"functional effect\": -0.5992, \"times_seen\": 119.0}, {\"site\": 1199, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.49738843214953565, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.12344076098618956, \"functional effect\": -0.2673, \"times_seen\": 22.0}, {\"site\": 1199, \"mutant\": \"S\", \"log2 fold change IC90\": -0.08161680583632559, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.08263435586519145, \"functional effect\": -0.4779, \"times_seen\": 7.0}, {\"site\": 1199, \"mutant\": \"V\", \"log2 fold change IC90\": 0.057489743120707565, \"epitope\": \"all\", \"reference_site\": \"1202\", \"IC90\": 0.09099884706581, \"functional effect\": -0.4334, \"times_seen\": 13.0}, {\"site\": 1200, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1200, \"mutant\": \"F\", \"log2 fold change IC90\": -0.17177048883940008, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.07762858738089554, \"functional effect\": -0.5025, \"times_seen\": 48.0}, {\"site\": 1200, \"mutant\": \"H\", \"log2 fold change IC90\": -0.026551529941672754, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08584933706995541, \"functional effect\": -2.377, \"times_seen\": 5.0}, {\"site\": 1200, \"mutant\": \"I\", \"log2 fold change IC90\": 0.02013103184522479, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08867267238100714, \"functional effect\": -0.37, \"times_seen\": 12.0}, {\"site\": 1200, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1200, \"mutant\": \"M\", \"log2 fold change IC90\": -0.08115004780873496, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08266109504976585, \"functional effect\": -0.075, \"times_seen\": 28.0}, {\"site\": 1200, \"mutant\": \"P\", \"log2 fold change IC90\": 0.008182407845743625, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08794130439297433, \"functional effect\": -1.7428, \"times_seen\": 12.0}, {\"site\": 1200, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.23108695372102742, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.10263461499032109, \"functional effect\": -1.8301, \"times_seen\": 8.0}, {\"site\": 1200, \"mutant\": \"R\", \"log2 fold change IC90\": -0.004234514521348024, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08718766301093095, \"functional effect\": -1.7863, \"times_seen\": 2.0}, {\"site\": 1200, \"mutant\": \"V\", \"log2 fold change IC90\": -0.004675469050167808, \"epitope\": \"all\", \"reference_site\": \"1203\", \"IC90\": 0.08716101848872647, \"functional effect\": -1.007, \"times_seen\": 1.0}, {\"site\": 1201, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1201, \"mutant\": \"A\", \"log2 fold change IC90\": -0.016407103268078465, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08645512092873013, \"functional effect\": -0.4525, \"times_seen\": 2.0}, {\"site\": 1201, \"mutant\": \"C\", \"log2 fold change IC90\": -0.018917417873958217, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08630481830861053, \"functional effect\": -1.2555, \"times_seen\": 4.0}, {\"site\": 1201, \"mutant\": \"D\", \"log2 fold change IC90\": 0.10457087118711778, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.0940175049689824, \"functional effect\": -0.3785, \"times_seen\": 34.0}, {\"site\": 1201, \"mutant\": \"E\", \"log2 fold change IC90\": -0.018445852261900104, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08633303288997829, \"functional effect\": -0.9138, \"times_seen\": 2.0}, {\"site\": 1201, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1201, \"mutant\": \"R\", \"log2 fold change IC90\": -0.03031907743131516, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08562543701859587, \"functional effect\": -0.8861, \"times_seen\": 8.0}, {\"site\": 1201, \"mutant\": \"S\", \"log2 fold change IC90\": -0.07922510345775503, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.08277146086086903, \"functional effect\": -0.3427, \"times_seen\": 31.0}, {\"site\": 1201, \"mutant\": \"V\", \"log2 fold change IC90\": -2.1225964808746642, \"epitope\": \"all\", \"reference_site\": \"1204\", \"IC90\": 0.020080038603166612, \"functional effect\": -1.2251, \"times_seen\": 12.0}, {\"site\": 1202, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1202, \"mutant\": \"E\", \"log2 fold change IC90\": 0.13553198052533585, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.09605698351505133, \"functional effect\": 0.1113, \"times_seen\": 12.0}, {\"site\": 1202, \"mutant\": \"I\", \"log2 fold change IC90\": -0.00965964371090048, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.08686041706491741, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1202, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1202, \"mutant\": \"N\", \"log2 fold change IC90\": 0.006595796689866309, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.08784464366072896, \"functional effect\": 0.1242, \"times_seen\": 56.0}, {\"site\": 1202, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0015584841329968847, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.08753846023701561, \"functional effect\": -0.0272, \"times_seen\": 17.0}, {\"site\": 1202, \"mutant\": \"R\", \"log2 fold change IC90\": 0.07192081498509248, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.09191366325959192, \"functional effect\": -0.0534, \"times_seen\": 29.0}, {\"site\": 1202, \"mutant\": \"T\", \"log2 fold change IC90\": 0.19944538345626936, \"epitope\": \"all\", \"reference_site\": \"1205\", \"IC90\": 0.10040811078373563, \"functional effect\": 0.1046, \"times_seen\": 22.0}, {\"site\": 1203, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0025552659310032174, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08728920560804719, \"functional effect\": 0.4763, \"times_seen\": 1.0}, {\"site\": 1203, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0077167126274003016, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08791292193192304, \"functional effect\": -1.5381, \"times_seen\": 7.0}, {\"site\": 1203, \"mutant\": \"F\", \"log2 fold change IC90\": -0.039423159530967616, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08508680167470521, \"functional effect\": -0.1585, \"times_seen\": 21.0}, {\"site\": 1203, \"mutant\": \"H\", \"log2 fold change IC90\": -0.00854837334434807, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.0869273491536977, \"functional effect\": -0.9419, \"times_seen\": 13.0}, {\"site\": 1203, \"mutant\": \"N\", \"log2 fold change IC90\": -0.009625671366560475, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08686246246374238, \"functional effect\": -1.0559, \"times_seen\": 2.0}, {\"site\": 1203, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0024232155178382526, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.08729719558712846, \"functional effect\": -0.5054, \"times_seen\": 1.0}, {\"site\": 1203, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1206\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1204, \"mutant\": \"*\", \"log2 fold change IC90\": -0.005585711412705562, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08710604316402046, \"functional effect\": -1.7288, \"times_seen\": 1.0}, {\"site\": 1204, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004405050546123315, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08717735746590079, \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1204, \"mutant\": \"A\", \"log2 fold change IC90\": -0.006966642114601566, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08702270617634376, \"functional effect\": -0.9284, \"times_seen\": 8.0}, {\"site\": 1204, \"mutant\": \"D\", \"log2 fold change IC90\": -0.480480143095767, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.06267449126461758, \"functional effect\": -0.2349, \"times_seen\": 79.0}, {\"site\": 1204, \"mutant\": \"E\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1204, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0025787059870089465, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08760038616941294, \"functional effect\": -1.075, \"times_seen\": 14.0}, {\"site\": 1204, \"mutant\": \"K\", \"log2 fold change IC90\": -0.020462894666673767, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08621241438871631, \"functional effect\": -1.1686, \"times_seen\": 91.0}, {\"site\": 1204, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": null, \"functional effect\": -0.2522, \"times_seen\": null}, {\"site\": 1204, \"mutant\": \"V\", \"log2 fold change IC90\": -0.018295769264139353, \"epitope\": \"all\", \"reference_site\": \"1207\", \"IC90\": 0.08634201454861029, \"functional effect\": -0.544, \"times_seen\": 20.0}, {\"site\": 1205, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": null, \"functional effect\": -2.8389, \"times_seen\": null}, {\"site\": 1205, \"mutant\": \"-\", \"log2 fold change IC90\": -0.005768709623094799, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08709499492538648, \"functional effect\": -1.1367, \"times_seen\": 1.0}, {\"site\": 1205, \"mutant\": \"E\", \"log2 fold change IC90\": -0.017531679187302963, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08638775571240616, \"functional effect\": 0.2082, \"times_seen\": 101.0}, {\"site\": 1205, \"mutant\": \"H\", \"log2 fold change IC90\": -0.26812181439963945, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.07261344545419755, \"functional effect\": -0.5391, \"times_seen\": 131.0}, {\"site\": 1205, \"mutant\": \"K\", \"log2 fold change IC90\": -0.049639079817749024, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08448641863680305, \"functional effect\": -1.0514, \"times_seen\": 61.0}, {\"site\": 1205, \"mutant\": \"L\", \"log2 fold change IC90\": -0.07195989176581881, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.08318933773438349, \"functional effect\": -0.3741, \"times_seen\": 25.0}, {\"site\": 1205, \"mutant\": \"M\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": null, \"functional effect\": -0.8033, \"times_seen\": null}, {\"site\": 1205, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1205, \"mutant\": \"R\", \"log2 fold change IC90\": -0.2682171847865733, \"epitope\": \"all\", \"reference_site\": \"1208\", \"IC90\": 0.07260864544913646, \"functional effect\": -1.2458, \"times_seen\": 30.0}, {\"site\": 1206, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": null, \"functional effect\": -2.9748, \"times_seen\": null}, {\"site\": 1206, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1206, \"mutant\": \"C\", \"log2 fold change IC90\": -0.014342944322962469, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08657890650519791, \"functional effect\": -1.5884, \"times_seen\": 5.0}, {\"site\": 1206, \"mutant\": \"D\", \"log2 fold change IC90\": -0.007624862692622917, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08698301166747485, \"functional effect\": -0.9888, \"times_seen\": 1.0}, {\"site\": 1206, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": null, \"functional effect\": -0.5447, \"times_seen\": null}, {\"site\": 1206, \"mutant\": \"H\", \"log2 fold change IC90\": -0.12301560499851681, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08029682361585538, \"functional effect\": -1.1283, \"times_seen\": 22.0}, {\"site\": 1206, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0021269901618977695, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08731512196597883, \"functional effect\": -0.3489, \"times_seen\": 1.0}, {\"site\": 1206, \"mutant\": \"N\", \"log2 fold change IC90\": -0.006113975187358212, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.08707415385799504, \"functional effect\": -1.2513, \"times_seen\": 1.0}, {\"site\": 1206, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1209\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": null, \"functional effect\": -2.6414, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"L\", \"log2 fold change IC90\": 0.01144102738651942, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.08814016217217052, \"functional effect\": -0.2619, \"times_seen\": 14.0}, {\"site\": 1207, \"mutant\": \"M\", \"log2 fold change IC90\": 1.2075134981471722, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.20194241049694123, \"functional effect\": -0.1508, \"times_seen\": 17.0}, {\"site\": 1207, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": null, \"functional effect\": -1.3902, \"times_seen\": null}, {\"site\": 1207, \"mutant\": \"T\", \"log2 fold change IC90\": 0.04548641210791, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.09024487074804918, \"functional effect\": -0.6196, \"times_seen\": 43.0}, {\"site\": 1207, \"mutant\": \"V\", \"log2 fold change IC90\": -0.644146003102327, \"epitope\": \"all\", \"reference_site\": \"1210\", \"IC90\": 0.05595288501290489, \"functional effect\": -0.0089, \"times_seen\": 38.0}, {\"site\": 1208, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": -2.8901, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"E\", \"log2 fold change IC90\": -0.02815744463962795, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.08575382831403679, \"functional effect\": -2.2165, \"times_seen\": 6.0}, {\"site\": 1208, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": 1.3076, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1208, \"mutant\": \"M\", \"log2 fold change IC90\": 0.002221642551420078, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.08757870797440075, \"functional effect\": -0.5475, \"times_seen\": 2.0}, {\"site\": 1208, \"mutant\": \"N\", \"log2 fold change IC90\": 0.09608799125383613, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.09346631497149828, \"functional effect\": -0.6971, \"times_seen\": 21.0}, {\"site\": 1208, \"mutant\": \"R\", \"log2 fold change IC90\": 0.010063851228668126, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": 0.08805606497289274, \"functional effect\": -0.1191, \"times_seen\": 5.0}, {\"site\": 1208, \"mutant\": \"T\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1211\", \"IC90\": null, \"functional effect\": -0.9017, \"times_seen\": null}, {\"site\": 1209, \"mutant\": \"*\", \"log2 fold change IC90\": 0.04329544247825715, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.09010792308871207, \"functional effect\": -2.4534, \"times_seen\": 5.0}, {\"site\": 1209, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": null, \"functional effect\": -1.2385, \"times_seen\": null}, {\"site\": 1209, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04751271287186819, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08461103373496107, \"functional effect\": -2.3843, \"times_seen\": 14.0}, {\"site\": 1209, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0027706020580795915, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08727617782585655, \"functional effect\": -2.2355, \"times_seen\": 1.0}, {\"site\": 1209, \"mutant\": \"L\", \"log2 fold change IC90\": 0.021881420816118602, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08878032220223216, \"functional effect\": -2.2128, \"times_seen\": 14.0}, {\"site\": 1209, \"mutant\": \"R\", \"log2 fold change IC90\": -0.006730062511493824, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.08703697772011217, \"functional effect\": -2.4587, \"times_seen\": 2.0}, {\"site\": 1209, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1212\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": null, \"functional effect\": -0.9333, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"L\", \"log2 fold change IC90\": -0.009462271806893728, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.08687230105853318, \"functional effect\": -2.2115, \"times_seen\": 3.0}, {\"site\": 1210, \"mutant\": \"P\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.050945647217402565, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.08440993869715001, \"functional effect\": -1.333, \"times_seen\": 6.0}, {\"site\": 1210, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": null, \"functional effect\": -1.1673, \"times_seen\": null}, {\"site\": 1210, \"mutant\": \"S\", \"log2 fold change IC90\": -0.09523371530799118, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.08185807886253435, \"functional effect\": -1.0767, \"times_seen\": 37.0}, {\"site\": 1210, \"mutant\": \"T\", \"log2 fold change IC90\": -0.007206540464254928, \"epitope\": \"all\", \"reference_site\": \"1213\", \"IC90\": 0.08700823682047365, \"functional effect\": -1.9568, \"times_seen\": 4.0}, {\"site\": 1211, \"mutant\": \"*\", \"log2 fold change IC90\": -0.021445953538280795, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08615368887306087, \"functional effect\": -2.4638, \"times_seen\": 8.0}, {\"site\": 1211, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1211, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03597345892712306, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08529050044169716, \"functional effect\": -2.5278, \"times_seen\": 19.0}, {\"site\": 1211, \"mutant\": \"F\", \"log2 fold change IC90\": 0.027346654758740326, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.0891172786678526, \"functional effect\": -0.6012, \"times_seen\": 19.0}, {\"site\": 1211, \"mutant\": \"G\", \"log2 fold change IC90\": 0.050601849623395465, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.09056542456315532, \"functional effect\": -1.6721, \"times_seen\": 11.0}, {\"site\": 1211, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0742709981947492, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.09206351474130683, \"functional effect\": -1.6378, \"times_seen\": 23.0}, {\"site\": 1211, \"mutant\": \"R\", \"log2 fold change IC90\": -0.02185175780472774, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08612945879188748, \"functional effect\": -2.2108, \"times_seen\": 5.0}, {\"site\": 1211, \"mutant\": \"S\", \"log2 fold change IC90\": -0.006418918847449261, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.08705575086610305, \"functional effect\": -1.5455, \"times_seen\": 1.0}, {\"site\": 1211, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1214\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1212, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": null, \"functional effect\": -3.1551, \"times_seen\": null}, {\"site\": 1212, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1212, \"mutant\": \"C\", \"log2 fold change IC90\": -0.03388706610395669, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.08541393486010478, \"functional effect\": -2.2095, \"times_seen\": 6.0}, {\"site\": 1212, \"mutant\": \"F\", \"log2 fold change IC90\": 0.08762409642904403, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.09291957916270197, \"functional effect\": -0.3552, \"times_seen\": 50.0}, {\"site\": 1212, \"mutant\": \"H\", \"log2 fold change IC90\": 0.261425541382542, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.10481578286560236, \"functional effect\": -1.0761, \"times_seen\": 111.0}, {\"site\": 1212, \"mutant\": \"N\", \"log2 fold change IC90\": -0.363902262897548, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.06794918564797356, \"functional effect\": -0.9324, \"times_seen\": 37.0}, {\"site\": 1212, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1215\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"F\", \"log2 fold change IC90\": 0.6461516666028919, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.1368487346781716, \"functional effect\": -1.6606, \"times_seen\": 39.0}, {\"site\": 1213, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"L\", \"log2 fold change IC90\": 0.011310194608846027, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.08813216942314867, \"functional effect\": -0.6364, \"times_seen\": 35.0}, {\"site\": 1213, \"mutant\": \"M\", \"log2 fold change IC90\": -0.10681898740969244, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.08120336632571754, \"functional effect\": -0.7324, \"times_seen\": 45.0}, {\"site\": 1213, \"mutant\": \"N\", \"log2 fold change IC90\": -0.002671350751536067, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.08728218226366534, \"functional effect\": -0.375, \"times_seen\": 1.0}, {\"site\": 1213, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": null, \"functional effect\": -0.4976, \"times_seen\": null}, {\"site\": 1213, \"mutant\": \"S\", \"log2 fold change IC90\": 0.7678806858749738, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.1488966313551174, \"functional effect\": -0.4035, \"times_seen\": 72.0}, {\"site\": 1213, \"mutant\": \"T\", \"log2 fold change IC90\": -0.7634985997088914, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.0515102636364624, \"functional effect\": -0.1313, \"times_seen\": 114.0}, {\"site\": 1213, \"mutant\": \"V\", \"log2 fold change IC90\": 0.05166667380450177, \"epitope\": \"all\", \"reference_site\": \"1216\", \"IC90\": 0.09063229375511866, \"functional effect\": -0.0003, \"times_seen\": 69.0}, {\"site\": 1214, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0064131045967224035, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08783352037737549, \"functional effect\": -2.8152, \"times_seen\": 8.0}, {\"site\": 1214, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1214, \"mutant\": \"C\", \"log2 fold change IC90\": -0.017787883850639164, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08637241568551894, \"functional effect\": -1.7056, \"times_seen\": 3.0}, {\"site\": 1214, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": null, \"functional effect\": -1.5744, \"times_seen\": null}, {\"site\": 1214, \"mutant\": \"L\", \"log2 fold change IC90\": -0.00474732799260925, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08715667720907136, \"functional effect\": -1.4455, \"times_seen\": 59.0}, {\"site\": 1214, \"mutant\": \"R\", \"log2 fold change IC90\": 0.026012508629596396, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.08903490470032499, \"functional effect\": -2.4405, \"times_seen\": 1.0}, {\"site\": 1214, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": null, \"functional effect\": -3.1288, \"times_seen\": null}, {\"site\": 1214, \"mutant\": \"W\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1217\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"I\", \"log2 fold change IC90\": -0.12222960954947698, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.0803405820897978, \"functional effect\": -0.4166, \"times_seen\": 12.0}, {\"site\": 1215, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"M\", \"log2 fold change IC90\": 0.038462775265753875, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08980658908312754, \"functional effect\": -0.5232, \"times_seen\": 6.0}, {\"site\": 1215, \"mutant\": \"P\", \"log2 fold change IC90\": 0.018292613295135506, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08855974923430959, \"functional effect\": -1.3295, \"times_seen\": 12.0}, {\"site\": 1215, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.005323372269766928, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08712188393551058, \"functional effect\": -1.5515, \"times_seen\": 1.0}, {\"site\": 1215, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": null, \"functional effect\": -2.8079, \"times_seen\": null}, {\"site\": 1215, \"mutant\": \"V\", \"log2 fold change IC90\": -0.005378832466240349, \"epitope\": \"all\", \"reference_site\": \"1218\", \"IC90\": 0.08711853485355474, \"functional effect\": -0.9749, \"times_seen\": 1.0}, {\"site\": 1216, \"mutant\": \"*\", \"log2 fold change IC90\": 0.011391686506699372, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08813714778682977, \"functional effect\": -2.5133, \"times_seen\": 9.0}, {\"site\": 1216, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1216, \"mutant\": \"A\", \"log2 fold change IC90\": 0.6540591740285738, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.13760087106206836, \"functional effect\": 0.3553, \"times_seen\": 153.0}, {\"site\": 1216, \"mutant\": \"C\", \"log2 fold change IC90\": 0.5519643972065819, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.1281998724002337, \"functional effect\": 0.3015, \"times_seen\": 136.0}, {\"site\": 1216, \"mutant\": \"D\", \"log2 fold change IC90\": 0.06956899313407071, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.09176395146328578, \"functional effect\": -0.747, \"times_seen\": 89.0}, {\"site\": 1216, \"mutant\": \"E\", \"log2 fold change IC90\": -0.34170944019854244, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.06900252157056971, \"functional effect\": -0.219, \"times_seen\": 52.0}, {\"site\": 1216, \"mutant\": \"F\", \"log2 fold change IC90\": 0.009506133073085194, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08802203077065651, \"functional effect\": 0.0226, \"times_seen\": 32.0}, {\"site\": 1216, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1216, \"mutant\": \"H\", \"log2 fold change IC90\": -0.1288962351824216, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.07997018849987522, \"functional effect\": -0.5841, \"times_seen\": 20.0}, {\"site\": 1216, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04708263110879595, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.09034477425681015, \"functional effect\": -0.1738, \"times_seen\": 43.0}, {\"site\": 1216, \"mutant\": \"K\", \"log2 fold change IC90\": 0.19309767004758746, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.09996729565433352, \"functional effect\": -1.1434, \"times_seen\": 27.0}, {\"site\": 1216, \"mutant\": \"L\", \"log2 fold change IC90\": -6.0494889342530795, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.0013202376851137927, \"functional effect\": -0.0576, \"times_seen\": 87.0}, {\"site\": 1216, \"mutant\": \"M\", \"log2 fold change IC90\": 0.038103491175888474, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08978422672634247, \"functional effect\": 0.1474, \"times_seen\": 22.0}, {\"site\": 1216, \"mutant\": \"N\", \"log2 fold change IC90\": -0.022766356210980537, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.086074874212757, \"functional effect\": -0.1172, \"times_seen\": 28.0}, {\"site\": 1216, \"mutant\": \"P\", \"log2 fold change IC90\": -0.1052150331474238, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08129369651411993, \"functional effect\": -0.8864, \"times_seen\": 48.0}, {\"site\": 1216, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.15868224658253732, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.07833604419729824, \"functional effect\": -0.063, \"times_seen\": 24.0}, {\"site\": 1216, \"mutant\": \"R\", \"log2 fold change IC90\": -0.025929366942178577, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08588636762612624, \"functional effect\": -1.5016, \"times_seen\": 105.0}, {\"site\": 1216, \"mutant\": \"S\", \"log2 fold change IC90\": -0.9431842762909437, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.045478171410258256, \"functional effect\": 0.0718, \"times_seen\": 263.0}, {\"site\": 1216, \"mutant\": \"T\", \"log2 fold change IC90\": 0.20834694555402972, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.10102955333970776, \"functional effect\": -0.0003, \"times_seen\": 56.0}, {\"site\": 1216, \"mutant\": \"V\", \"log2 fold change IC90\": -0.01735938869726601, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08639807298467041, \"functional effect\": -0.0735, \"times_seen\": 166.0}, {\"site\": 1216, \"mutant\": \"W\", \"log2 fold change IC90\": -0.04666859116549242, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.08466055418575301, \"functional effect\": -0.1293, \"times_seen\": 51.0}, {\"site\": 1216, \"mutant\": \"Y\", \"log2 fold change IC90\": 1.0705704306217576, \"epitope\": \"all\", \"reference_site\": \"1219\", \"IC90\": 0.18365534186584812, \"functional effect\": -0.5349, \"times_seen\": 27.0}, {\"site\": 1217, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1217, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": null, \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 1217, \"mutant\": \"F\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1217, \"mutant\": \"I\", \"log2 fold change IC90\": 0.11536476742187751, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.09472355922899038, \"functional effect\": -1.1032, \"times_seen\": 79.0}, {\"site\": 1217, \"mutant\": \"L\", \"log2 fold change IC90\": -0.019032642756097694, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08629792560771032, \"functional effect\": -1.0528, \"times_seen\": 26.0}, {\"site\": 1217, \"mutant\": \"S\", \"log2 fold change IC90\": -0.06474782620330718, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08360624433424754, \"functional effect\": -2.1484, \"times_seen\": 11.0}, {\"site\": 1217, \"mutant\": \"V\", \"log2 fold change IC90\": 0.01480718168383373, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.08834605446062484, \"functional effect\": -1.2837, \"times_seen\": 4.0}, {\"site\": 1217, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007422655580382398, \"epitope\": \"all\", \"reference_site\": \"1220\", \"IC90\": 0.0869952039990238, \"functional effect\": -0.9808, \"times_seen\": 2.0}, {\"site\": 1218, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1218, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1218, \"mutant\": \"L\", \"log2 fold change IC90\": 0.056459367966087116, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.0909338787436057, \"functional effect\": 0.065, \"times_seen\": 36.0}, {\"site\": 1218, \"mutant\": \"M\", \"log2 fold change IC90\": -0.013481951473625901, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.08663059176465833, \"functional effect\": -0.1515, \"times_seen\": 48.0}, {\"site\": 1218, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02501136698654124, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.08594103529270301, \"functional effect\": -0.4276, \"times_seen\": 6.0}, {\"site\": 1218, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": null, \"functional effect\": -0.4574, \"times_seen\": null}, {\"site\": 1218, \"mutant\": \"T\", \"log2 fold change IC90\": 0.9025671329329168, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.1634667894268292, \"functional effect\": -0.0778, \"times_seen\": 52.0}, {\"site\": 1218, \"mutant\": \"V\", \"log2 fold change IC90\": -0.9544920474089597, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.04512310908973476, \"functional effect\": -0.1469, \"times_seen\": 133.0}, {\"site\": 1218, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.025390295520097597, \"epitope\": \"all\", \"reference_site\": \"1221\", \"IC90\": 0.08591846556506909, \"functional effect\": -1.1376, \"times_seen\": 23.0}, {\"site\": 1219, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1219, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1219, \"mutant\": \"D\", \"log2 fold change IC90\": 0.01007007338140344, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.08805644474786356, \"functional effect\": 0.2087, \"times_seen\": 5.0}, {\"site\": 1219, \"mutant\": \"P\", \"log2 fold change IC90\": 0.009038069704814787, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.08799347781637325, \"functional effect\": 0.1067, \"times_seen\": 1.0}, {\"site\": 1219, \"mutant\": \"S\", \"log2 fold change IC90\": 0.02372337020437842, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.08889374416048229, \"functional effect\": 0.0033, \"times_seen\": 39.0}, {\"site\": 1219, \"mutant\": \"T\", \"log2 fold change IC90\": 0.35291874157964076, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.11167832203774872, \"functional effect\": -0.0723, \"times_seen\": 95.0}, {\"site\": 1219, \"mutant\": \"V\", \"log2 fold change IC90\": 0.6429197295076167, \"epitope\": \"all\", \"reference_site\": \"1222\", \"IC90\": 0.13654250816989458, \"functional effect\": -0.6226, \"times_seen\": 79.0}, {\"site\": 1220, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": null, \"functional effect\": -2.9327, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"A\", \"log2 fold change IC90\": 0.020616180699143925, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08870249620257101, \"functional effect\": -0.387, \"times_seen\": 1.0}, {\"site\": 1220, \"mutant\": \"C\", \"log2 fold change IC90\": -0.001809545573738565, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08733433653441876, \"functional effect\": -0.4959, \"times_seen\": 29.0}, {\"site\": 1220, \"mutant\": \"E\", \"log2 fold change IC90\": -0.015371246650745594, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08651721809036612, \"functional effect\": -1.5139, \"times_seen\": 11.0}, {\"site\": 1220, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"K\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": null, \"functional effect\": -2.9582, \"times_seen\": null}, {\"site\": 1220, \"mutant\": \"R\", \"log2 fold change IC90\": -0.12888382972517406, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.07997087615110553, \"functional effect\": -2.5374, \"times_seen\": 22.0}, {\"site\": 1220, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0001505250900130792, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.08745307112757376, \"functional effect\": -0.6865, \"times_seen\": 41.0}, {\"site\": 1220, \"mutant\": \"V\", \"log2 fold change IC90\": -0.05141893784940107, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.0843822517087384, \"functional effect\": -0.8444, \"times_seen\": 19.0}, {\"site\": 1220, \"mutant\": \"W\", \"log2 fold change IC90\": 0.048812211309869236, \"epitope\": \"all\", \"reference_site\": \"1223\", \"IC90\": 0.09045314936824449, \"functional effect\": -1.0369, \"times_seen\": 19.0}, {\"site\": 1221, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": null, \"functional effect\": -0.4525, \"times_seen\": null}, {\"site\": 1221, \"mutant\": \"F\", \"log2 fold change IC90\": -0.09579985742041877, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08182596243283367, \"functional effect\": -0.2175, \"times_seen\": 34.0}, {\"site\": 1221, \"mutant\": \"I\", \"log2 fold change IC90\": -0.013521006699216314, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08662824661796191, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1221, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1221, \"mutant\": \"M\", \"log2 fold change IC90\": -0.0705031749122259, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08327337802566742, \"functional effect\": -0.0817, \"times_seen\": 24.0}, {\"site\": 1221, \"mutant\": \"P\", \"log2 fold change IC90\": 0.010508409551130969, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08808320313262502, \"functional effect\": -1.9729, \"times_seen\": 1.0}, {\"site\": 1221, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": null, \"functional effect\": -0.7297, \"times_seen\": null}, {\"site\": 1221, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0411883153131257, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08498276054849016, \"functional effect\": -0.298, \"times_seen\": 44.0}, {\"site\": 1221, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03329241040145677, \"epitope\": \"all\", \"reference_site\": \"1224\", \"IC90\": 0.08544914836762711, \"functional effect\": -0.2853, \"times_seen\": 16.0}, {\"site\": 1222, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1222, \"mutant\": \"F\", \"log2 fold change IC90\": 0.018926508470408002, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08859866940171947, \"functional effect\": 0.1961, \"times_seen\": 50.0}, {\"site\": 1222, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1222, \"mutant\": \"L\", \"log2 fold change IC90\": 0.10023543483230676, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.09373539748147924, \"functional effect\": 0.0194, \"times_seen\": 17.0}, {\"site\": 1222, \"mutant\": \"M\", \"log2 fold change IC90\": 0.5153448827127938, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.12498676303103638, \"functional effect\": 0.2032, \"times_seen\": 21.0}, {\"site\": 1222, \"mutant\": \"N\", \"log2 fold change IC90\": 0.018717424642053365, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08858583009321536, \"functional effect\": 0.173, \"times_seen\": 3.0}, {\"site\": 1222, \"mutant\": \"S\", \"log2 fold change IC90\": -0.017786488997549636, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08637249919373495, \"functional effect\": 0.2097, \"times_seen\": 19.0}, {\"site\": 1222, \"mutant\": \"T\", \"log2 fold change IC90\": 0.07582700039892397, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.092162862355639, \"functional effect\": 0.1205, \"times_seen\": 16.0}, {\"site\": 1222, \"mutant\": \"V\", \"log2 fold change IC90\": -0.00661710466315922, \"epitope\": \"all\", \"reference_site\": \"1225\", \"IC90\": 0.08704379267015093, \"functional effect\": 0.1733, \"times_seen\": 40.0}, {\"site\": 1223, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": null, \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 1223, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1223, \"mutant\": \"E\", \"log2 fold change IC90\": 0.000562027330336384, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.08747801906632337, \"functional effect\": -1.1596, \"times_seen\": 5.0}, {\"site\": 1223, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": null, \"functional effect\": -0.4402, \"times_seen\": null}, {\"site\": 1223, \"mutant\": \"S\", \"log2 fold change IC90\": -0.001756238156299221, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.08733756358782567, \"functional effect\": -0.3103, \"times_seen\": 21.0}, {\"site\": 1223, \"mutant\": \"T\", \"log2 fold change IC90\": -0.7460014682124896, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.052138788310952755, \"functional effect\": -0.0057, \"times_seen\": 66.0}, {\"site\": 1223, \"mutant\": \"V\", \"log2 fold change IC90\": 0.2095717932733202, \"epitope\": \"all\", \"reference_site\": \"1226\", \"IC90\": 0.101115363825939, \"functional effect\": -0.1725, \"times_seen\": 94.0}, {\"site\": 1224, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": null, \"functional effect\": -1.7015, \"times_seen\": null}, {\"site\": 1224, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0029789451355385953, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08726357497211995, \"functional effect\": -2.3523, \"times_seen\": 1.0}, {\"site\": 1224, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1224, \"mutant\": \"K\", \"log2 fold change IC90\": -0.024383873094620957, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08597842309999613, \"functional effect\": -2.8078, \"times_seen\": 7.0}, {\"site\": 1224, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0015399342221966966, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08753733469062948, \"functional effect\": -0.6899, \"times_seen\": 13.0}, {\"site\": 1224, \"mutant\": \"M\", \"log2 fold change IC90\": 0.6779312758277624, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.13989667800997604, \"functional effect\": -0.1915, \"times_seen\": 77.0}, {\"site\": 1224, \"mutant\": \"N\", \"log2 fold change IC90\": -0.02459869040412563, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.0859656218648045, \"functional effect\": -1.8437, \"times_seen\": 3.0}, {\"site\": 1224, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": null, \"functional effect\": -1.1773, \"times_seen\": null}, {\"site\": 1224, \"mutant\": \"T\", \"log2 fold change IC90\": -0.045526409770536104, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.08472760646985943, \"functional effect\": -0.466, \"times_seen\": 13.0}, {\"site\": 1224, \"mutant\": \"V\", \"log2 fold change IC90\": 0.10016728159611227, \"epitope\": \"all\", \"reference_site\": \"1227\", \"IC90\": 0.09373096950494116, \"functional effect\": -0.2212, \"times_seen\": 41.0}, {\"site\": 1225, \"mutant\": \"*\", \"log2 fold change IC90\": 0.02772489905590887, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.0891406464071487, \"functional effect\": -2.4181, \"times_seen\": 10.0}, {\"site\": 1225, \"mutant\": \"-\", \"log2 fold change IC90\": 0.03522720162708175, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08960540295157574, \"functional effect\": -1.0511, \"times_seen\": 1.0}, {\"site\": 1225, \"mutant\": \"A\", \"log2 fold change IC90\": -0.010832197631535824, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08678984972942037, \"functional effect\": 0.0799, \"times_seen\": 139.0}, {\"site\": 1225, \"mutant\": \"C\", \"log2 fold change IC90\": -0.3174324621172031, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.07017348740064613, \"functional effect\": -0.0272, \"times_seen\": 55.0}, {\"site\": 1225, \"mutant\": \"D\", \"log2 fold change IC90\": 1.60079475673559, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.2652265471722593, \"functional effect\": -1.5675, \"times_seen\": 37.0}, {\"site\": 1225, \"mutant\": \"E\", \"log2 fold change IC90\": -2.0876203311651174, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.02057280045019298, \"functional effect\": -1.0143, \"times_seen\": 89.0}, {\"site\": 1225, \"mutant\": \"F\", \"log2 fold change IC90\": 0.3242624284475413, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.1094819364273632, \"functional effect\": 0.1416, \"times_seen\": 65.0}, {\"site\": 1225, \"mutant\": \"G\", \"log2 fold change IC90\": 0.017924368325937308, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08853714742344437, \"functional effect\": 0.1317, \"times_seen\": 139.0}, {\"site\": 1225, \"mutant\": \"H\", \"log2 fold change IC90\": 0.014296171509459521, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08831476736464695, \"functional effect\": -0.8873, \"times_seen\": 39.0}, {\"site\": 1225, \"mutant\": \"I\", \"log2 fold change IC90\": 0.25511923322753194, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.10435861206554323, \"functional effect\": 0.0404, \"times_seen\": 95.0}, {\"site\": 1225, \"mutant\": \"K\", \"log2 fold change IC90\": -0.0710993993625266, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08323897063903195, \"functional effect\": -0.7357, \"times_seen\": 42.0}, {\"site\": 1225, \"mutant\": \"L\", \"log2 fold change IC90\": 0.07974365052395117, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.09241340741387169, \"functional effect\": 0.0479, \"times_seen\": 209.0}, {\"site\": 1225, \"mutant\": \"M\", \"log2 fold change IC90\": -0.25107425685391976, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.07347656928996071, \"functional effect\": 0.0496, \"times_seen\": 59.0}, {\"site\": 1225, \"mutant\": \"N\", \"log2 fold change IC90\": -0.0595675956414819, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08390698572343229, \"functional effect\": -0.8236, \"times_seen\": 33.0}, {\"site\": 1225, \"mutant\": \"P\", \"log2 fold change IC90\": -1.784444582039205, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.02538390349752687, \"functional effect\": -0.7, \"times_seen\": 66.0}, {\"site\": 1225, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.7614158968571006, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.051584678563647346, \"functional effect\": -0.7127, \"times_seen\": 46.0}, {\"site\": 1225, \"mutant\": \"R\", \"log2 fold change IC90\": -0.022594327376900807, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08608513850472047, \"functional effect\": -2.7184, \"times_seen\": 47.0}, {\"site\": 1225, \"mutant\": \"S\", \"log2 fold change IC90\": 0.06561281742928507, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.09151265995591976, \"functional effect\": -0.1117, \"times_seen\": 95.0}, {\"site\": 1225, \"mutant\": \"T\", \"log2 fold change IC90\": 0.26596010252370167, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.10514574955823883, \"functional effect\": -0.1155, \"times_seen\": 92.0}, {\"site\": 1225, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1225, \"mutant\": \"W\", \"log2 fold change IC90\": 0.04060960654591586, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08994032705960339, \"functional effect\": -0.3215, \"times_seen\": 55.0}, {\"site\": 1225, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.06603700417431181, \"epitope\": \"all\", \"reference_site\": \"1228\", \"IC90\": 0.08353156799401942, \"functional effect\": -0.723, \"times_seen\": 45.0}, {\"site\": 1226, \"mutant\": \"-\", \"log2 fold change IC90\": 0.03038037722371298, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08930487309191518, \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1226, \"mutant\": \"I\", \"log2 fold change IC90\": 0.029017515402896685, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08922054984342041, \"functional effect\": -0.2766, \"times_seen\": 98.0}, {\"site\": 1226, \"mutant\": \"K\", \"log2 fold change IC90\": -0.013428910746266617, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08663377679956612, \"functional effect\": 0.2572, \"times_seen\": 2.0}, {\"site\": 1226, \"mutant\": \"L\", \"log2 fold change IC90\": -1.179294977821333, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.03861238170325077, \"functional effect\": -0.1168, \"times_seen\": 41.0}, {\"site\": 1226, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1226, \"mutant\": \"R\", \"log2 fold change IC90\": -0.010091149631895596, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.0868344412498192, \"functional effect\": -1.5001, \"times_seen\": 1.0}, {\"site\": 1226, \"mutant\": \"T\", \"log2 fold change IC90\": -0.1464758523445093, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.07900164376497683, \"functional effect\": 0.0645, \"times_seen\": 57.0}, {\"site\": 1226, \"mutant\": \"V\", \"log2 fold change IC90\": 0.014381620468400698, \"epitope\": \"all\", \"reference_site\": \"1229\", \"IC90\": 0.08831999828885675, \"functional effect\": -0.2728, \"times_seen\": 81.0}, {\"site\": 1227, \"mutant\": \"-\", \"log2 fold change IC90\": -0.016505133412690987, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.0864492465617772, \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1227, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02362271189734365, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08602379700405806, \"functional effect\": -0.0708, \"times_seen\": 16.0}, {\"site\": 1227, \"mutant\": \"E\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": null, \"functional effect\": -2.0124, \"times_seen\": null}, {\"site\": 1227, \"mutant\": \"G\", \"log2 fold change IC90\": 0.032777067352590596, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08945335491581023, \"functional effect\": -0.0254, \"times_seen\": 14.0}, {\"site\": 1227, \"mutant\": \"L\", \"log2 fold change IC90\": -0.04064227783328683, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.08501493128017135, \"functional effect\": -0.0927, \"times_seen\": 43.0}, {\"site\": 1227, \"mutant\": \"M\", \"log2 fold change IC90\": -0.21117830536260962, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.07553682883942832, \"functional effect\": -0.0999, \"times_seen\": 48.0}, {\"site\": 1227, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1230\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1228, \"mutant\": \"-\", \"log2 fold change IC90\": -0.021480086877333125, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.08615165055019841, \"functional effect\": -0.9001, \"times_seen\": 1.0}, {\"site\": 1228, \"mutant\": \"A\", \"log2 fold change IC90\": 0.05803798510819517, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.09103343432635638, \"functional effect\": 0.1554, \"times_seen\": 49.0}, {\"site\": 1228, \"mutant\": \"I\", \"log2 fold change IC90\": -0.9245081224516257, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.04607072819024499, \"functional effect\": -0.5252, \"times_seen\": 53.0}, {\"site\": 1228, \"mutant\": \"K\", \"log2 fold change IC90\": 0.006719076274679799, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.08785215038501787, \"functional effect\": -1.7746, \"times_seen\": 17.0}, {\"site\": 1228, \"mutant\": \"S\", \"log2 fold change IC90\": -0.019143758312210622, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.0862912792462398, \"functional effect\": 0.3093, \"times_seen\": 8.0}, {\"site\": 1228, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1231\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1229, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": null, \"functional effect\": -0.882, \"times_seen\": null}, {\"site\": 1229, \"mutant\": \"F\", \"log2 fold change IC90\": -0.010039877154055991, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08683752734629417, \"functional effect\": -0.1186, \"times_seen\": 8.0}, {\"site\": 1229, \"mutant\": \"I\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1229, \"mutant\": \"K\", \"log2 fold change IC90\": -0.01691114669201075, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08642492083625573, \"functional effect\": 0.0471, \"times_seen\": 4.0}, {\"site\": 1229, \"mutant\": \"L\", \"log2 fold change IC90\": -0.00865011835355598, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08692121888234895, \"functional effect\": -0.1578, \"times_seen\": 15.0}, {\"site\": 1229, \"mutant\": \"M\", \"log2 fold change IC90\": -0.009821513649953682, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08685067189959934, \"functional effect\": -0.1257, \"times_seen\": 2.0}, {\"site\": 1229, \"mutant\": \"S\", \"log2 fold change IC90\": 0.013610420731780959, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.0882727990153904, \"functional effect\": -0.4748, \"times_seen\": 14.0}, {\"site\": 1229, \"mutant\": \"T\", \"log2 fold change IC90\": 0.031887442369052756, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08939821130884307, \"functional effect\": -0.2131, \"times_seen\": 31.0}, {\"site\": 1229, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03720169360057993, \"epitope\": \"all\", \"reference_site\": \"1232\", \"IC90\": 0.08521791949600205, \"functional effect\": 0.0215, \"times_seen\": 40.0}, {\"site\": 1230, \"mutant\": \"-\", \"log2 fold change IC90\": -0.006096562361873449, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08707520481897603, \"functional effect\": 0.3177, \"times_seen\": 1.0}, {\"site\": 1230, \"mutant\": \"I\", \"log2 fold change IC90\": 0.06096095263283013, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.09121805928166825, \"functional effect\": -0.0475, \"times_seen\": 125.0}, {\"site\": 1230, \"mutant\": \"K\", \"log2 fold change IC90\": -0.010010984089432844, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08683926647157184, \"functional effect\": -1.3499, \"times_seen\": 1.0}, {\"site\": 1230, \"mutant\": \"L\", \"log2 fold change IC90\": -0.12406317700895966, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08023853952221319, \"functional effect\": -0.0947, \"times_seen\": 26.0}, {\"site\": 1230, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1230, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.039205731634899016, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08985284942137677, \"functional effect\": -0.8916, \"times_seen\": 5.0}, {\"site\": 1230, \"mutant\": \"R\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": null, \"functional effect\": -1.8772, \"times_seen\": null}, {\"site\": 1230, \"mutant\": \"T\", \"log2 fold change IC90\": -0.007840661443073608, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08697000169593304, \"functional effect\": -0.1748, \"times_seen\": 52.0}, {\"site\": 1230, \"mutant\": \"V\", \"log2 fold change IC90\": -0.08501805404033387, \"epitope\": \"all\", \"reference_site\": \"1233\", \"IC90\": 0.08243976941546637, \"functional effect\": 0.0275, \"times_seen\": 99.0}, {\"site\": 1231, \"mutant\": \"-\", \"log2 fold change IC90\": -0.00591353735326197, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08708625216481769, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1231, \"mutant\": \"F\", \"log2 fold change IC90\": -0.0011958958219678859, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08737149206060252, \"functional effect\": -0.1091, \"times_seen\": 32.0}, {\"site\": 1231, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0011026118293615064, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08737714164342728, \"functional effect\": -0.0854, \"times_seen\": 11.0}, {\"site\": 1231, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1231, \"mutant\": \"M\", \"log2 fold change IC90\": -0.00032034285300031534, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08742453278282049, \"functional effect\": -0.1194, \"times_seen\": 9.0}, {\"site\": 1231, \"mutant\": \"P\", \"log2 fold change IC90\": -0.08969035033290161, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08217321275163607, \"functional effect\": -0.6804, \"times_seen\": 25.0}, {\"site\": 1231, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.010852286477342078, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08678864123024303, \"functional effect\": -0.7067, \"times_seen\": 3.0}, {\"site\": 1231, \"mutant\": \"R\", \"log2 fold change IC90\": 0.017599213381688093, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": 0.08851719514905064, \"functional effect\": -2.3997, \"times_seen\": 1.0}, {\"site\": 1231, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1234\", \"IC90\": null, \"functional effect\": -0.2956, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006706359609268504, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08703840771457522, \"functional effect\": -2.6874, \"times_seen\": 2.0}, {\"site\": 1232, \"mutant\": \"-\", \"log2 fold change IC90\": -0.011601275744554863, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08674359575063331, \"functional effect\": -2.8968, \"times_seen\": 4.0}, {\"site\": 1232, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"F\", \"log2 fold change IC90\": 0.013920785924690631, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08829179107583983, \"functional effect\": -0.1193, \"times_seen\": 71.0}, {\"site\": 1232, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": null, \"functional effect\": -0.0671, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"L\", \"log2 fold change IC90\": -0.10760041555981287, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08115939486070775, \"functional effect\": -0.0483, \"times_seen\": 17.0}, {\"site\": 1232, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005633209646069441, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08710317539575273, \"functional effect\": -1.224, \"times_seen\": 1.0}, {\"site\": 1232, \"mutant\": \"S\", \"log2 fold change IC90\": -0.028494111318981052, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.0857338191731819, \"functional effect\": -0.4282, \"times_seen\": 29.0}, {\"site\": 1232, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": null, \"functional effect\": -0.5153, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"W\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": null, \"functional effect\": -1.4835, \"times_seen\": null}, {\"site\": 1232, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.047552075146458005, \"epitope\": \"all\", \"reference_site\": \"1235\", \"IC90\": 0.08460872525173001, \"functional effect\": -1.4152, \"times_seen\": 8.0}, {\"site\": 1233, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": null, \"functional effect\": -1.6538, \"times_seen\": null}, {\"site\": 1233, \"mutant\": \"-\", \"log2 fold change IC90\": -0.009883955459165636, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.08684691296540133, \"functional effect\": 0.4444, \"times_seen\": 3.0}, {\"site\": 1233, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1233, \"mutant\": \"F\", \"log2 fold change IC90\": 0.5117779230395805, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.12467812395458412, \"functional effect\": -0.4074, \"times_seen\": 50.0}, {\"site\": 1233, \"mutant\": \"R\", \"log2 fold change IC90\": 0.01036244411726649, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.08807429171877326, \"functional effect\": -1.1882, \"times_seen\": 3.0}, {\"site\": 1233, \"mutant\": \"S\", \"log2 fold change IC90\": -0.5724903503710139, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.0588021201494176, \"functional effect\": -0.4697, \"times_seen\": 55.0}, {\"site\": 1233, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.006176247563937233, \"epitope\": \"all\", \"reference_site\": \"1236\", \"IC90\": 0.08707039547710152, \"functional effect\": -1.3228, \"times_seen\": 57.0}, {\"site\": 1234, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0035178839439865875, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.0872309825374245, \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1234, \"mutant\": \"I\", \"log2 fold change IC90\": -0.02797280491844176, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08576480400588746, \"functional effect\": 0.0143, \"times_seen\": 86.0}, {\"site\": 1234, \"mutant\": \"K\", \"log2 fold change IC90\": 0.009502282464716494, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08802179583679565, \"functional effect\": -1.6031, \"times_seen\": 30.0}, {\"site\": 1234, \"mutant\": \"L\", \"log2 fold change IC90\": -0.11380679595001178, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08081100233209801, \"functional effect\": -0.0706, \"times_seen\": 29.0}, {\"site\": 1234, \"mutant\": \"M\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1234, \"mutant\": \"R\", \"log2 fold change IC90\": -0.0031616438651187787, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.08725252486492985, \"functional effect\": -1.1254, \"times_seen\": 1.0}, {\"site\": 1234, \"mutant\": \"T\", \"log2 fold change IC90\": 0.5314603892271376, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.12639074433665287, \"functional effect\": -0.4804, \"times_seen\": 61.0}, {\"site\": 1234, \"mutant\": \"V\", \"log2 fold change IC90\": -0.1995299782355016, \"epitope\": \"all\", \"reference_site\": \"1237\", \"IC90\": 0.07614918232720819, \"functional effect\": -0.032, \"times_seen\": 81.0}, {\"site\": 1235, \"mutant\": \"-\", \"log2 fold change IC90\": -0.038850037598361545, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.08512060978957171, \"functional effect\": 0.0882, \"times_seen\": 2.0}, {\"site\": 1235, \"mutant\": \"A\", \"log2 fold change IC90\": -0.058394608013546054, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.08397523429662503, \"functional effect\": -0.0204, \"times_seen\": 38.0}, {\"site\": 1235, \"mutant\": \"I\", \"log2 fold change IC90\": -0.24615837280073943, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.07372736268048183, \"functional effect\": -0.004, \"times_seen\": 106.0}, {\"site\": 1235, \"mutant\": \"N\", \"log2 fold change IC90\": -3.9465098357014785, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.005671682538970215, \"functional effect\": -1.0371, \"times_seen\": 69.0}, {\"site\": 1235, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": null, \"functional effect\": -0.5267, \"times_seen\": null}, {\"site\": 1235, \"mutant\": \"S\", \"log2 fold change IC90\": -0.044846163214205675, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.08476756588675152, \"functional effect\": 0.0467, \"times_seen\": 38.0}, {\"site\": 1235, \"mutant\": \"T\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1238\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1236, \"mutant\": \"-\", \"log2 fold change IC90\": -0.010631976462727835, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.0868018954983057, \"functional effect\": -0.8685, \"times_seen\": 5.0}, {\"site\": 1236, \"mutant\": \"A\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": null, \"functional effect\": -2.9838, \"times_seen\": null}, {\"site\": 1236, \"mutant\": \"C\", \"log2 fold change IC90\": 0.059914508742154676, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.09115191919798915, \"functional effect\": -0.1208, \"times_seen\": 55.0}, {\"site\": 1236, \"mutant\": \"F\", \"log2 fold change IC90\": -0.01385884644491622, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08660796302541958, \"functional effect\": -1.3003, \"times_seen\": 4.0}, {\"site\": 1236, \"mutant\": \"G\", \"log2 fold change IC90\": -0.11245002930688314, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08088703589502669, \"functional effect\": -0.2297, \"times_seen\": 60.0}, {\"site\": 1236, \"mutant\": \"I\", \"log2 fold change IC90\": -1.416359504422403, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.032761445643565305, \"functional effect\": -0.5828, \"times_seen\": 49.0}, {\"site\": 1236, \"mutant\": \"N\", \"log2 fold change IC90\": -0.00925444642375568, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08688481622576764, \"functional effect\": -0.3604, \"times_seen\": 31.0}, {\"site\": 1236, \"mutant\": \"P\", \"log2 fold change IC90\": 2.3933614532046668, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.4594130639457941, \"functional effect\": -1.0785, \"times_seen\": 21.0}, {\"site\": 1236, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1236, \"mutant\": \"T\", \"log2 fold change IC90\": -1.039484272592327, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.04254159872233498, \"functional effect\": 0.0624, \"times_seen\": 114.0}, {\"site\": 1236, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.03919293537471866, \"epitope\": \"all\", \"reference_site\": \"1239\", \"IC90\": 0.08510038084400508, \"functional effect\": -0.2845, \"times_seen\": 3.0}, {\"site\": 1237, \"mutant\": \"*\", \"log2 fold change IC90\": -0.003064892857398275, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.0872583764500104, \"functional effect\": -2.0316, \"times_seen\": 3.0}, {\"site\": 1237, \"mutant\": \"-\", \"log2 fold change IC90\": -0.008044574615583049, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08695771006449737, \"functional effect\": -0.6744, \"times_seen\": 9.0}, {\"site\": 1237, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1237, \"mutant\": \"F\", \"log2 fold change IC90\": -0.12392239270033503, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08024636992169557, \"functional effect\": -0.1106, \"times_seen\": 25.0}, {\"site\": 1237, \"mutant\": \"G\", \"log2 fold change IC90\": 0.09654378749176108, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.09349584881190208, \"functional effect\": -0.5082, \"times_seen\": 16.0}, {\"site\": 1237, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0029004651254555393, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08761992555046914, \"functional effect\": -1.4729, \"times_seen\": 32.0}, {\"site\": 1237, \"mutant\": \"S\", \"log2 fold change IC90\": -0.019476351633811107, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.08627138828214251, \"functional effect\": -1.1017, \"times_seen\": 14.0}, {\"site\": 1237, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.06162915539988627, \"epitope\": \"all\", \"reference_site\": \"1240\", \"IC90\": 0.09126031788480854, \"functional effect\": -0.9946, \"times_seen\": 28.0}, {\"site\": 1238, \"mutant\": \"*\", \"log2 fold change IC90\": -0.033297248373935794, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08544886182062772, \"functional effect\": -1.7553, \"times_seen\": 4.0}, {\"site\": 1238, \"mutant\": \"-\", \"log2 fold change IC90\": -0.010547271295770974, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08680699206042897, \"functional effect\": 0.1308, \"times_seen\": 9.0}, {\"site\": 1238, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1238, \"mutant\": \"F\", \"log2 fold change IC90\": 1.9357787348533235, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.33454705948487007, \"functional effect\": -0.2409, \"times_seen\": 22.0}, {\"site\": 1238, \"mutant\": \"G\", \"log2 fold change IC90\": -0.004514824858529185, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.0871707244144741, \"functional effect\": -2.1346, \"times_seen\": 1.0}, {\"site\": 1238, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": null, \"functional effect\": -0.8018, \"times_seen\": null}, {\"site\": 1238, \"mutant\": \"R\", \"log2 fold change IC90\": -0.015177783150694285, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08652882071300566, \"functional effect\": -1.4508, \"times_seen\": 10.0}, {\"site\": 1238, \"mutant\": \"S\", \"log2 fold change IC90\": -0.011995873631786703, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08671987337131519, \"functional effect\": -0.5981, \"times_seen\": 14.0}, {\"site\": 1238, \"mutant\": \"W\", \"log2 fold change IC90\": -0.003682503355212284, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.08722102957207996, \"functional effect\": -0.7344, \"times_seen\": 1.0}, {\"site\": 1238, \"mutant\": \"Y\", \"log2 fold change IC90\": -1.4994995411368535, \"epitope\": \"all\", \"reference_site\": \"1241\", \"IC90\": 0.030926830381413226, \"functional effect\": -0.7287, \"times_seen\": 76.0}, {\"site\": 1239, \"mutant\": \"-\", \"log2 fold change IC90\": -0.0028740880147808093, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08726991764294943, \"functional effect\": -0.0966, \"times_seen\": 8.0}, {\"site\": 1239, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0005553213551032881, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08747761244950603, \"functional effect\": 0.1894, \"times_seen\": 1.0}, {\"site\": 1239, \"mutant\": \"C\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": null, \"functional effect\": -0.2083, \"times_seen\": null}, {\"site\": 1239, \"mutant\": \"F\", \"log2 fold change IC90\": -0.010131594511438543, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08683200694514, \"functional effect\": -0.2464, \"times_seen\": 10.0}, {\"site\": 1239, \"mutant\": \"G\", \"log2 fold change IC90\": 0.43902564297341706, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.11854674674622188, \"functional effect\": -0.1266, \"times_seen\": 30.0}, {\"site\": 1239, \"mutant\": \"I\", \"log2 fold change IC90\": 0.04412395379881371, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.0901596851540901, \"functional effect\": 0.0166, \"times_seen\": 66.0}, {\"site\": 1239, \"mutant\": \"K\", \"log2 fold change IC90\": 0.006465386755541787, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08783670345428396, \"functional effect\": 0.1954, \"times_seen\": 1.0}, {\"site\": 1239, \"mutant\": \"N\", \"log2 fold change IC90\": 0.9357039015226788, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.16726485340380345, \"functional effect\": -0.3422, \"times_seen\": 64.0}, {\"site\": 1239, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": null, \"functional effect\": -1.4432, \"times_seen\": null}, {\"site\": 1239, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1239, \"mutant\": \"T\", \"log2 fold change IC90\": 0.016738924549499507, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.08846442747999256, \"functional effect\": 0.1987, \"times_seen\": 64.0}, {\"site\": 1239, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.14995052053032598, \"epitope\": \"all\", \"reference_site\": \"1242\", \"IC90\": 0.0970218066443733, \"functional effect\": 0.4444, \"times_seen\": 5.0}, {\"site\": 1240, \"mutant\": \"*\", \"log2 fold change IC90\": 0.019738863913997352, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.0886485717557618, \"functional effect\": -1.052, \"times_seen\": 1.0}, {\"site\": 1240, \"mutant\": \"-\", \"log2 fold change IC90\": -0.006711095030006156, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.0870381220250894, \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1240, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1240, \"mutant\": \"F\", \"log2 fold change IC90\": 0.1167714526310483, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.09481596351905969, \"functional effect\": -0.1029, \"times_seen\": 41.0}, {\"site\": 1240, \"mutant\": \"G\", \"log2 fold change IC90\": -0.0007572160658141889, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08739806311792411, \"functional effect\": -0.3107, \"times_seen\": 1.0}, {\"site\": 1240, \"mutant\": \"R\", \"log2 fold change IC90\": -0.44305928417746415, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.06432141923360468, \"functional effect\": -0.8646, \"times_seen\": 24.0}, {\"site\": 1240, \"mutant\": \"S\", \"log2 fold change IC90\": -0.028876930006076593, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08571107274854278, \"functional effect\": -0.1091, \"times_seen\": 7.0}, {\"site\": 1240, \"mutant\": \"V\", \"log2 fold change IC90\": 0.20874368120838138, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.10105733990341288, \"functional effect\": -0.324, \"times_seen\": 15.0}, {\"site\": 1240, \"mutant\": \"W\", \"log2 fold change IC90\": 0.18425615196017, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.09935652221462407, \"functional effect\": -0.3527, \"times_seen\": 53.0}, {\"site\": 1240, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.030346387607252567, \"epitope\": \"all\", \"reference_site\": \"1243\", \"IC90\": 0.08562381614685916, \"functional effect\": -0.5323, \"times_seen\": 48.0}, {\"site\": 1241, \"mutant\": \"-\", \"log2 fold change IC90\": -0.007871333564314536, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08696815270775159, \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1241, \"mutant\": \"F\", \"log2 fold change IC90\": 0.005028111603270339, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08774924030856252, \"functional effect\": -0.1396, \"times_seen\": 30.0}, {\"site\": 1241, \"mutant\": \"I\", \"log2 fold change IC90\": -0.0221792274791941, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08610991094272444, \"functional effect\": 0.0979, \"times_seen\": 11.0}, {\"site\": 1241, \"mutant\": \"L\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1241, \"mutant\": \"M\", \"log2 fold change IC90\": 0.029186672630552763, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08923101164252617, \"functional effect\": 0.1033, \"times_seen\": 9.0}, {\"site\": 1241, \"mutant\": \"P\", \"log2 fold change IC90\": -0.4461154362009966, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.06418530732692347, \"functional effect\": -0.8224, \"times_seen\": 56.0}, {\"site\": 1241, \"mutant\": \"Q\", \"log2 fold change IC90\": -0.01532428393919498, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08652003445083994, \"functional effect\": -0.5007, \"times_seen\": 3.0}, {\"site\": 1241, \"mutant\": \"R\", \"log2 fold change IC90\": -0.005870322900619211, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.08708886078339478, \"functional effect\": 0.2253, \"times_seen\": 1.0}, {\"site\": 1241, \"mutant\": \"V\", \"log2 fold change IC90\": -0.03925607279643217, \"epitope\": \"all\", \"reference_site\": \"1244\", \"IC90\": 0.0850966566327812, \"functional effect\": -0.0203, \"times_seen\": 28.0}, {\"site\": 1242, \"mutant\": \"*\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": null, \"functional effect\": -1.5664, \"times_seen\": null}, {\"site\": 1242, \"mutant\": \"-\", \"log2 fold change IC90\": -0.013508534278189861, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08662899554174998, \"functional effect\": -0.3766, \"times_seen\": 8.0}, {\"site\": 1242, \"mutant\": \"E\", \"log2 fold change IC90\": -0.014125845079611139, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08659193602902249, \"functional effect\": -0.2488, \"times_seen\": 37.0}, {\"site\": 1242, \"mutant\": \"G\", \"log2 fold change IC90\": -0.013322738575627296, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08664015266857417, \"functional effect\": -0.0008, \"times_seen\": 1.0}, {\"site\": 1242, \"mutant\": \"I\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": null, \"functional effect\": -2.3704, \"times_seen\": null}, {\"site\": 1242, \"mutant\": \"K\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1242, \"mutant\": \"M\", \"log2 fold change IC90\": -1.3006459251213849, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.03549738130024407, \"functional effect\": 0.0314, \"times_seen\": 28.0}, {\"site\": 1242, \"mutant\": \"N\", \"log2 fold change IC90\": -0.8831251840137784, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.04741137847433346, \"functional effect\": -0.0857, \"times_seen\": 57.0}, {\"site\": 1242, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.03741962464712789, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08974167727860195, \"functional effect\": -0.6612, \"times_seen\": 4.0}, {\"site\": 1242, \"mutant\": \"R\", \"log2 fold change IC90\": 0.03847206166920133, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.08980716715602509, \"functional effect\": -0.0745, \"times_seen\": 79.0}, {\"site\": 1242, \"mutant\": \"T\", \"log2 fold change IC90\": -0.08088545428520873, \"epitope\": \"all\", \"reference_site\": \"1245\", \"IC90\": 0.0826762566712797, \"functional effect\": -0.2072, \"times_seen\": 14.0}, {\"site\": 1243, \"mutant\": \"-\", \"log2 fold change IC90\": -0.004173147734487337, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.08719137172301236, \"functional effect\": 0.1697, \"times_seen\": 6.0}, {\"site\": 1243, \"mutant\": \"A\", \"log2 fold change IC90\": 0.0013434991213468555, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.08752541655541439, \"functional effect\": 0.1369, \"times_seen\": 1.0}, {\"site\": 1243, \"mutant\": \"C\", \"log2 fold change IC90\": 0.10096228287023111, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.0937826344604826, \"functional effect\": -0.1513, \"times_seen\": 72.0}, {\"site\": 1243, \"mutant\": \"D\", \"log2 fold change IC90\": -0.15680097318081307, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.07843826097917193, \"functional effect\": -0.2387, \"times_seen\": 105.0}, {\"site\": 1243, \"mutant\": \"F\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": null, \"functional effect\": -0.3658, \"times_seen\": null}, {\"site\": 1243, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1243, \"mutant\": \"S\", \"log2 fold change IC90\": 0.35247011160389885, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.11164359920843815, \"functional effect\": -0.0637, \"times_seen\": 71.0}, {\"site\": 1243, \"mutant\": \"V\", \"log2 fold change IC90\": 0.0010369323994867414, \"epitope\": \"all\", \"reference_site\": \"1246\", \"IC90\": 0.08750681974278973, \"functional effect\": -0.2773, \"times_seen\": 68.0}, {\"site\": 1244, \"mutant\": \"*\", \"log2 fold change IC90\": -0.0011962469717466833, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08737147079451682, \"functional effect\": -0.5813, \"times_seen\": 1.0}, {\"site\": 1244, \"mutant\": \"-\", \"log2 fold change IC90\": -0.00015995321742650996, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08743425262521431, \"functional effect\": -1.9998, \"times_seen\": 1.0}, {\"site\": 1244, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1244, \"mutant\": \"F\", \"log2 fold change IC90\": -0.05037183676047453, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08444351817001693, \"functional effect\": -0.3644, \"times_seen\": 62.0}, {\"site\": 1244, \"mutant\": \"G\", \"log2 fold change IC90\": 0.01613062230514647, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08842713493729236, \"functional effect\": -0.8924, \"times_seen\": 2.0}, {\"site\": 1244, \"mutant\": \"L\", \"log2 fold change IC90\": -0.06402501891239104, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08364814254707852, \"functional effect\": -0.138, \"times_seen\": 24.0}, {\"site\": 1244, \"mutant\": \"R\", \"log2 fold change IC90\": 0.0403604187084056, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08992479356185458, \"functional effect\": -0.551, \"times_seen\": 31.0}, {\"site\": 1244, \"mutant\": \"S\", \"log2 fold change IC90\": 1.2045113096352327, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.2015226136621767, \"functional effect\": -0.3998, \"times_seen\": 43.0}, {\"site\": 1244, \"mutant\": \"W\", \"log2 fold change IC90\": 0.4353560771994927, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.11824560041952419, \"functional effect\": -0.3368, \"times_seen\": 26.0}, {\"site\": 1244, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.007370429182386443, \"epitope\": \"all\", \"reference_site\": \"1247\", \"IC90\": 0.08699835333291468, \"functional effect\": -0.815, \"times_seen\": 37.0}, {\"site\": 1245, \"mutant\": \"*\", \"log2 fold change IC90\": -0.006101118099098297, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08707492985364075, \"functional effect\": -0.4376, \"times_seen\": 1.0}, {\"site\": 1245, \"mutant\": \"-\", \"log2 fold change IC90\": 0.012224662958368354, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08818805069074388, \"functional effect\": 0.2266, \"times_seen\": 1.0}, {\"site\": 1245, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1245, \"mutant\": \"F\", \"log2 fold change IC90\": 0.20747710863312724, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.10096865845469306, \"functional effect\": -0.1572, \"times_seen\": 69.0}, {\"site\": 1245, \"mutant\": \"G\", \"log2 fold change IC90\": -0.027034397124825894, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08582060827425805, \"functional effect\": -0.5566, \"times_seen\": 16.0}, {\"site\": 1245, \"mutant\": \"L\", \"log2 fold change IC90\": -0.014708536171401344, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08655696941427578, \"functional effect\": -0.0698, \"times_seen\": 28.0}, {\"site\": 1245, \"mutant\": \"N\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": null, \"functional effect\": -0.5006, \"times_seen\": null}, {\"site\": 1245, \"mutant\": \"R\", \"log2 fold change IC90\": -0.39930574690177084, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.06630201778081793, \"functional effect\": -0.342, \"times_seen\": 32.0}, {\"site\": 1245, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0006272871460465417, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.0874819761940329, \"functional effect\": -0.321, \"times_seen\": 16.0}, {\"site\": 1245, \"mutant\": \"V\", \"log2 fold change IC90\": -0.14666186867279582, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.07899145821090944, \"functional effect\": -0.3538, \"times_seen\": 29.0}, {\"site\": 1245, \"mutant\": \"W\", \"log2 fold change IC90\": -0.05606838804112237, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08411074626182347, \"functional effect\": -0.1295, \"times_seen\": 44.0}, {\"site\": 1245, \"mutant\": \"Y\", \"log2 fold change IC90\": -0.05790500328238575, \"epitope\": \"all\", \"reference_site\": \"1248\", \"IC90\": 0.08400373765190149, \"functional effect\": -0.4627, \"times_seen\": 85.0}, {\"site\": 1246, \"mutant\": \"-\", \"log2 fold change IC90\": 0.020363119522845415, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08868693838279909, \"functional effect\": -0.7342, \"times_seen\": 2.0}, {\"site\": 1246, \"mutant\": \"A\", \"log2 fold change IC90\": -0.049898900900171565, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08447120448857312, \"functional effect\": -0.005, \"times_seen\": 26.0}, {\"site\": 1246, \"mutant\": \"C\", \"log2 fold change IC90\": -0.04977826300026841, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08447826825083454, \"functional effect\": -0.0657, \"times_seen\": 36.0}, {\"site\": 1246, \"mutant\": \"F\", \"log2 fold change IC90\": 0.04159174515244097, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.09000157627664651, \"functional effect\": -0.1038, \"times_seen\": 92.0}, {\"site\": 1246, \"mutant\": \"L\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": null, \"functional effect\": -0.079, \"times_seen\": null}, {\"site\": 1246, \"mutant\": \"P\", \"log2 fold change IC90\": 0.6515771755166926, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.13736434737711883, \"functional effect\": -0.219, \"times_seen\": 45.0}, {\"site\": 1246, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1246, \"mutant\": \"T\", \"log2 fold change IC90\": -0.025893833284876055, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08588848303808212, \"functional effect\": 0.2124, \"times_seen\": 30.0}, {\"site\": 1246, \"mutant\": \"V\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": null, \"functional effect\": -0.0951, \"times_seen\": null}, {\"site\": 1246, \"mutant\": \"Y\", \"log2 fold change IC90\": 0.004677353370977708, \"epitope\": \"all\", \"reference_site\": \"1249\", \"IC90\": 0.08772790868526681, \"functional effect\": 0.096, \"times_seen\": 30.0}, {\"site\": 1247, \"mutant\": \"*\", \"log2 fold change IC90\": -0.009706097513474243, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.08685762026338274, \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 1247, \"mutant\": \"-\", \"log2 fold change IC90\": 0.011343985287975247, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.0881342336714129, \"functional effect\": -0.3928, \"times_seen\": 2.0}, {\"site\": 1247, \"mutant\": \"C\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1247, \"mutant\": \"F\", \"log2 fold change IC90\": 0.6960572617964844, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.14166542450209801, \"functional effect\": 0.0678, \"times_seen\": 122.0}, {\"site\": 1247, \"mutant\": \"G\", \"log2 fold change IC90\": -1.3502943817628446, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.034296566249960476, \"functional effect\": -0.4042, \"times_seen\": 11.0}, {\"site\": 1247, \"mutant\": \"L\", \"log2 fold change IC90\": -0.7015720822326418, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.05376943982136699, \"functional effect\": -0.086, \"times_seen\": 26.0}, {\"site\": 1247, \"mutant\": \"P\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": null, \"functional effect\": -0.4455, \"times_seen\": null}, {\"site\": 1247, \"mutant\": \"Q\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": null, \"functional effect\": 0.6552, \"times_seen\": null}, {\"site\": 1247, \"mutant\": \"R\", \"log2 fold change IC90\": 0.08528791808899203, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.09276923481475702, \"functional effect\": 0.0299, \"times_seen\": 99.0}, {\"site\": 1247, \"mutant\": \"S\", \"log2 fold change IC90\": 0.017573240310231334, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.08851560157405766, \"functional effect\": -0.3167, \"times_seen\": 41.0}, {\"site\": 1247, \"mutant\": \"W\", \"log2 fold change IC90\": -0.1412940334605644, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.07928590915918853, \"functional effect\": -0.0876, \"times_seen\": 45.0}, {\"site\": 1247, \"mutant\": \"Y\", \"log2 fold change IC90\": -1.4491915997333051, \"epitope\": \"all\", \"reference_site\": \"1250\", \"IC90\": 0.03202429751517581, \"functional effect\": -0.0012, \"times_seen\": 125.0}, {\"site\": 1248, \"mutant\": \"-\", \"log2 fold change IC90\": 0.018765489187618518, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08858878145055263, \"functional effect\": -0.2543, \"times_seen\": 2.0}, {\"site\": 1248, \"mutant\": \"A\", \"log2 fold change IC90\": -0.02088418677786116, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08618724253574009, \"functional effect\": 0.0212, \"times_seen\": 9.0}, {\"site\": 1248, \"mutant\": \"C\", \"log2 fold change IC90\": -0.009414085852062234, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08687520263825971, \"functional effect\": 0.4135, \"times_seen\": 3.0}, {\"site\": 1248, \"mutant\": \"D\", \"log2 fold change IC90\": -0.027091760834811383, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08581719598650984, \"functional effect\": 0.1186, \"times_seen\": 40.0}, {\"site\": 1248, \"mutant\": \"E\", \"log2 fold change IC90\": 0.29114340152314333, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.1069972583652828, \"functional effect\": 0.0622, \"times_seen\": 55.0}, {\"site\": 1248, \"mutant\": \"G\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1248, \"mutant\": \"L\", \"log2 fold change IC90\": -0.0029905421137351473, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08726287351430646, \"functional effect\": 0.1906, \"times_seen\": 1.0}, {\"site\": 1248, \"mutant\": \"R\", \"log2 fold change IC90\": 0.057042924655996106, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.09097066808950814, \"functional effect\": 0.2094, \"times_seen\": 63.0}, {\"site\": 1248, \"mutant\": \"S\", \"log2 fold change IC90\": -0.0167949603900881, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.08643188127904505, \"functional effect\": 0.3219, \"times_seen\": 18.0}, {\"site\": 1248, \"mutant\": \"V\", \"log2 fold change IC90\": -0.015505766223186645, \"epitope\": \"all\", \"reference_site\": \"1251\", \"IC90\": 0.0865091514399051, \"functional effect\": 0.0905, \"times_seen\": 67.0}, {\"site\": 1249, \"mutant\": \"*\", \"log2 fold change IC90\": -0.02777161697801361, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08577676498652761, \"functional effect\": -0.0346, \"times_seen\": 49.0}, {\"site\": 1249, \"mutant\": \"-\", \"log2 fold change IC90\": 0.010927916481666322, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08810881969470691, \"functional effect\": 0.4444, \"times_seen\": 1.0}, {\"site\": 1249, \"mutant\": \"A\", \"log2 fold change IC90\": 0.009752753763702217, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08803707893325784, \"functional effect\": -0.0001, \"times_seen\": 81.0}, {\"site\": 1249, \"mutant\": \"C\", \"log2 fold change IC90\": -0.7807192640268679, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.0508990687039111, \"functional effect\": 0.3963, \"times_seen\": 143.0}, {\"site\": 1249, \"mutant\": \"D\", \"log2 fold change IC90\": 0.04485063069644218, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.09020510948942334, \"functional effect\": 0.1111, \"times_seen\": 45.0}, {\"site\": 1249, \"mutant\": \"E\", \"log2 fold change IC90\": -0.06718475272110143, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08346514015807396, \"functional effect\": -0.0168, \"times_seen\": 30.0}, {\"site\": 1249, \"mutant\": \"F\", \"log2 fold change IC90\": 0.006134937609053757, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08781658677060038, \"functional effect\": 0.397, \"times_seen\": 141.0}, {\"site\": 1249, \"mutant\": \"G\", \"log2 fold change IC90\": 0.25097077063581785, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.10405896041269028, \"functional effect\": -0.4074, \"times_seen\": 94.0}, {\"site\": 1249, \"mutant\": \"H\", \"log2 fold change IC90\": 0.19794563396572498, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.10030378605488083, \"functional effect\": 0.2924, \"times_seen\": 41.0}, {\"site\": 1249, \"mutant\": \"I\", \"log2 fold change IC90\": -0.09117517280508407, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08208868354535784, \"functional effect\": 0.4224, \"times_seen\": 50.0}, {\"site\": 1249, \"mutant\": \"K\", \"log2 fold change IC90\": -1.5900619711856852, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.029045135343841243, \"functional effect\": 0.1965, \"times_seen\": 40.0}, {\"site\": 1249, \"mutant\": \"L\", \"log2 fold change IC90\": -0.22833614972045796, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.07464379692418294, \"functional effect\": 0.3611, \"times_seen\": 101.0}, {\"site\": 1249, \"mutant\": \"M\", \"log2 fold change IC90\": -0.019001203774866516, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08629980621889198, \"functional effect\": 0.2764, \"times_seen\": 31.0}, {\"site\": 1249, \"mutant\": \"N\", \"log2 fold change IC90\": 0.020612992865185403, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08870230020237056, \"functional effect\": 0.397, \"times_seen\": 36.0}, {\"site\": 1249, \"mutant\": \"P\", \"log2 fold change IC90\": -0.004102381219468491, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08719564870510074, \"functional effect\": 0.2155, \"times_seen\": 158.0}, {\"site\": 1249, \"mutant\": \"Q\", \"log2 fold change IC90\": 0.024308573050198526, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08892980959542716, \"functional effect\": 0.3237, \"times_seen\": 25.0}, {\"site\": 1249, \"mutant\": \"R\", \"log2 fold change IC90\": 0.07430326283352001, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.0920655736859752, \"functional effect\": 0.2863, \"times_seen\": 95.0}, {\"site\": 1249, \"mutant\": \"S\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1249, \"mutant\": \"T\", \"log2 fold change IC90\": -0.02261932283416336, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08608364704692824, \"functional effect\": -0.2164, \"times_seen\": 136.0}, {\"site\": 1249, \"mutant\": \"V\", \"log2 fold change IC90\": -0.2162677047202809, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.075270826819553, \"functional effect\": 0.3255, \"times_seen\": 99.0}, {\"site\": 1249, \"mutant\": \"W\", \"log2 fold change IC90\": -0.004538819748357221, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.08716927460389376, \"functional effect\": 0.2297, \"times_seen\": 29.0}, {\"site\": 1249, \"mutant\": \"Y\", \"log2 fold change IC90\": -2.830022634147008, \"epitope\": \"all\", \"reference_site\": \"1252\", \"IC90\": 0.012297251396347419, \"functional effect\": 0.4444, \"times_seen\": 126.0}, {\"site\": 1250, \"mutant\": \"*\", \"log2 fold change IC90\": 0.0, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.0874439470962847, \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"-\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": null, \"functional effect\": -0.3058, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"G\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"L\", \"log2 fold change IC90\": -0.015441002257069571, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.08651303500597451, \"functional effect\": 0.3678, \"times_seen\": 5.0}, {\"site\": 1250, \"mutant\": \"R\", \"log2 fold change IC90\": -0.003428024364120212, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.08723641596814988, \"functional effect\": 0.397, \"times_seen\": 62.0}, {\"site\": 1250, \"mutant\": \"S\", \"log2 fold change IC90\": null, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": null, \"functional effect\": 0.4763, \"times_seen\": null}, {\"site\": 1250, \"mutant\": \"W\", \"log2 fold change IC90\": -0.016373226621373155, \"epitope\": \"all\", \"reference_site\": \"1253\", \"IC90\": 0.08645715104867319, \"functional effect\": 0.397, \"times_seen\": 2.0}], \"data-fec33ae205ff6712775e4252a9254f06\": [{\"site\": 1, \"wildtype\": \"M\", \"_stat_site_order\": 0}, {\"site\": 2, \"wildtype\": \"F\", \"_stat_site_order\": 1}, {\"site\": 3, \"wildtype\": \"V\", \"_stat_site_order\": 2}, {\"site\": 4, \"wildtype\": \"F\", \"_stat_site_order\": 3}, {\"site\": 5, \"wildtype\": \"L\", \"_stat_site_order\": 4}, {\"site\": 6, \"wildtype\": \"V\", \"_stat_site_order\": 5}, {\"site\": 7, \"wildtype\": \"L\", \"_stat_site_order\": 6}, {\"site\": 8, \"wildtype\": \"L\", \"_stat_site_order\": 7}, {\"site\": 9, \"wildtype\": \"P\", \"_stat_site_order\": 8}, {\"site\": 10, \"wildtype\": \"L\", \"_stat_site_order\": 9}, {\"site\": 11, \"wildtype\": \"V\", \"_stat_site_order\": 10}, {\"site\": 12, \"wildtype\": \"S\", \"_stat_site_order\": 11}, {\"site\": 13, \"wildtype\": \"S\", \"_stat_site_order\": 12}, {\"site\": 14, \"wildtype\": \"Q\", \"_stat_site_order\": 13}, {\"site\": 15, \"wildtype\": \"C\", \"_stat_site_order\": 14}, {\"site\": 16, \"wildtype\": \"V\", \"_stat_site_order\": 15}, {\"site\": 17, \"wildtype\": \"N\", \"_stat_site_order\": 16}, {\"site\": 18, \"wildtype\": \"L\", \"_stat_site_order\": 17}, {\"site\": 19, \"wildtype\": \"T\", \"_stat_site_order\": 18}, {\"site\": 20, \"wildtype\": \"T\", \"_stat_site_order\": 19}, {\"site\": 21, \"wildtype\": \"R\", \"_stat_site_order\": 20}, {\"site\": 22, \"wildtype\": \"T\", \"_stat_site_order\": 21}, {\"site\": 23, \"wildtype\": \"Q\", \"_stat_site_order\": 22}, {\"site\": 24, \"wildtype\": \"L\", \"_stat_site_order\": 23}, {\"site\": 25, \"wildtype\": \"P\", \"_stat_site_order\": 24}, {\"site\": 26, \"wildtype\": \"P\", \"_stat_site_order\": 25}, {\"site\": 27, \"wildtype\": \"A\", \"_stat_site_order\": 26}, {\"site\": 28, \"wildtype\": \"Y\", \"_stat_site_order\": 27}, {\"site\": 29, \"wildtype\": \"T\", \"_stat_site_order\": 28}, {\"site\": 30, \"wildtype\": \"N\", \"_stat_site_order\": 29}, {\"site\": 31, \"wildtype\": \"S\", \"_stat_site_order\": 30}, {\"site\": 32, \"wildtype\": \"F\", \"_stat_site_order\": 31}, {\"site\": 33, \"wildtype\": \"T\", \"_stat_site_order\": 32}, {\"site\": 34, \"wildtype\": \"R\", \"_stat_site_order\": 33}, {\"site\": 35, \"wildtype\": \"G\", \"_stat_site_order\": 34}, {\"site\": 36, \"wildtype\": \"V\", \"_stat_site_order\": 35}, {\"site\": 37, \"wildtype\": \"Y\", \"_stat_site_order\": 36}, {\"site\": 38, \"wildtype\": \"Y\", \"_stat_site_order\": 37}, {\"site\": 39, \"wildtype\": \"P\", \"_stat_site_order\": 38}, {\"site\": 40, \"wildtype\": \"D\", \"_stat_site_order\": 39}, {\"site\": 41, \"wildtype\": \"K\", \"_stat_site_order\": 40}, {\"site\": 42, \"wildtype\": \"V\", \"_stat_site_order\": 41}, {\"site\": 43, \"wildtype\": \"F\", \"_stat_site_order\": 42}, {\"site\": 44, \"wildtype\": \"R\", \"_stat_site_order\": 43}, {\"site\": 45, \"wildtype\": \"S\", \"_stat_site_order\": 44}, {\"site\": 46, \"wildtype\": \"S\", \"_stat_site_order\": 45}, {\"site\": 47, \"wildtype\": \"V\", \"_stat_site_order\": 46}, {\"site\": 48, \"wildtype\": \"L\", \"_stat_site_order\": 47}, {\"site\": 49, \"wildtype\": \"H\", \"_stat_site_order\": 48}, {\"site\": 50, \"wildtype\": \"S\", \"_stat_site_order\": 49}, {\"site\": 51, \"wildtype\": \"T\", \"_stat_site_order\": 50}, {\"site\": 52, \"wildtype\": \"Q\", \"_stat_site_order\": 51}, {\"site\": 53, \"wildtype\": \"D\", \"_stat_site_order\": 52}, {\"site\": 54, \"wildtype\": \"L\", \"_stat_site_order\": 53}, {\"site\": 55, \"wildtype\": \"F\", \"_stat_site_order\": 54}, {\"site\": 56, \"wildtype\": \"L\", \"_stat_site_order\": 55}, {\"site\": 57, \"wildtype\": \"P\", \"_stat_site_order\": 56}, {\"site\": 58, \"wildtype\": \"F\", \"_stat_site_order\": 57}, {\"site\": 59, \"wildtype\": \"F\", \"_stat_site_order\": 58}, {\"site\": 60, \"wildtype\": \"S\", \"_stat_site_order\": 59}, {\"site\": 61, \"wildtype\": \"N\", \"_stat_site_order\": 60}, {\"site\": 62, \"wildtype\": \"V\", \"_stat_site_order\": 61}, {\"site\": 63, \"wildtype\": \"T\", \"_stat_site_order\": 62}, {\"site\": 64, \"wildtype\": \"W\", \"_stat_site_order\": 63}, {\"site\": 65, \"wildtype\": \"F\", \"_stat_site_order\": 64}, {\"site\": 66, \"wildtype\": \"H\", \"_stat_site_order\": 65}, {\"site\": 67, \"wildtype\": \"V\", \"_stat_site_order\": 66}, {\"site\": 68, \"wildtype\": \"I\", \"_stat_site_order\": 67}, {\"site\": 69, \"wildtype\": \"S\", \"_stat_site_order\": 68}, {\"site\": 70, \"wildtype\": \"G\", \"_stat_site_order\": 69}, {\"site\": 71, \"wildtype\": \"T\", \"_stat_site_order\": 70}, {\"site\": 72, \"wildtype\": \"N\", \"_stat_site_order\": 71}, {\"site\": 73, \"wildtype\": \"G\", \"_stat_site_order\": 72}, {\"site\": 74, \"wildtype\": \"T\", \"_stat_site_order\": 73}, {\"site\": 75, \"wildtype\": \"K\", \"_stat_site_order\": 74}, {\"site\": 76, \"wildtype\": \"R\", \"_stat_site_order\": 75}, {\"site\": 77, \"wildtype\": \"F\", \"_stat_site_order\": 76}, {\"site\": 78, \"wildtype\": \"D\", \"_stat_site_order\": 77}, {\"site\": 79, \"wildtype\": \"N\", \"_stat_site_order\": 78}, {\"site\": 80, \"wildtype\": \"P\", \"_stat_site_order\": 79}, {\"site\": 81, \"wildtype\": \"V\", \"_stat_site_order\": 80}, {\"site\": 82, \"wildtype\": \"L\", \"_stat_site_order\": 81}, {\"site\": 83, \"wildtype\": \"P\", \"_stat_site_order\": 82}, {\"site\": 84, \"wildtype\": \"F\", \"_stat_site_order\": 83}, {\"site\": 85, \"wildtype\": \"N\", \"_stat_site_order\": 84}, {\"site\": 86, \"wildtype\": \"D\", \"_stat_site_order\": 85}, {\"site\": 87, \"wildtype\": \"G\", \"_stat_site_order\": 86}, {\"site\": 88, \"wildtype\": \"V\", \"_stat_site_order\": 87}, {\"site\": 89, \"wildtype\": \"Y\", \"_stat_site_order\": 88}, {\"site\": 90, \"wildtype\": \"F\", \"_stat_site_order\": 89}, {\"site\": 91, \"wildtype\": \"A\", \"_stat_site_order\": 90}, {\"site\": 92, \"wildtype\": \"S\", \"_stat_site_order\": 91}, {\"site\": 93, \"wildtype\": \"I\", \"_stat_site_order\": 92}, {\"site\": 94, \"wildtype\": \"E\", \"_stat_site_order\": 93}, {\"site\": 95, \"wildtype\": \"K\", \"_stat_site_order\": 94}, {\"site\": 96, \"wildtype\": \"S\", \"_stat_site_order\": 95}, {\"site\": 97, \"wildtype\": \"N\", \"_stat_site_order\": 96}, {\"site\": 98, \"wildtype\": \"I\", \"_stat_site_order\": 97}, {\"site\": 99, \"wildtype\": \"I\", \"_stat_site_order\": 98}, {\"site\": 100, \"wildtype\": \"R\", \"_stat_site_order\": 99}, {\"site\": 101, \"wildtype\": \"G\", \"_stat_site_order\": 100}, {\"site\": 102, \"wildtype\": \"W\", \"_stat_site_order\": 101}, {\"site\": 103, \"wildtype\": \"I\", \"_stat_site_order\": 102}, {\"site\": 104, \"wildtype\": \"F\", \"_stat_site_order\": 103}, {\"site\": 105, \"wildtype\": \"G\", \"_stat_site_order\": 104}, {\"site\": 106, \"wildtype\": \"T\", \"_stat_site_order\": 105}, {\"site\": 107, \"wildtype\": \"T\", \"_stat_site_order\": 106}, {\"site\": 108, \"wildtype\": \"L\", \"_stat_site_order\": 107}, {\"site\": 109, \"wildtype\": \"D\", \"_stat_site_order\": 108}, {\"site\": 110, \"wildtype\": \"S\", \"_stat_site_order\": 109}, {\"site\": 111, \"wildtype\": \"K\", \"_stat_site_order\": 110}, {\"site\": 112, \"wildtype\": \"T\", \"_stat_site_order\": 111}, {\"site\": 113, \"wildtype\": \"Q\", \"_stat_site_order\": 112}, {\"site\": 114, \"wildtype\": \"S\", \"_stat_site_order\": 113}, {\"site\": 115, \"wildtype\": \"L\", \"_stat_site_order\": 114}, {\"site\": 116, \"wildtype\": \"L\", \"_stat_site_order\": 115}, {\"site\": 117, \"wildtype\": \"I\", \"_stat_site_order\": 116}, {\"site\": 118, \"wildtype\": \"V\", \"_stat_site_order\": 117}, {\"site\": 119, \"wildtype\": \"N\", \"_stat_site_order\": 118}, {\"site\": 120, \"wildtype\": \"N\", \"_stat_site_order\": 119}, {\"site\": 121, \"wildtype\": \"A\", \"_stat_site_order\": 120}, {\"site\": 122, \"wildtype\": \"T\", \"_stat_site_order\": 121}, {\"site\": 123, \"wildtype\": \"N\", \"_stat_site_order\": 122}, {\"site\": 124, \"wildtype\": \"V\", \"_stat_site_order\": 123}, {\"site\": 125, \"wildtype\": \"V\", \"_stat_site_order\": 124}, {\"site\": 126, \"wildtype\": \"I\", \"_stat_site_order\": 125}, {\"site\": 127, \"wildtype\": \"K\", \"_stat_site_order\": 126}, {\"site\": 128, \"wildtype\": \"V\", \"_stat_site_order\": 127}, {\"site\": 129, \"wildtype\": \"C\", \"_stat_site_order\": 128}, {\"site\": 130, \"wildtype\": \"E\", \"_stat_site_order\": 129}, {\"site\": 131, \"wildtype\": \"F\", \"_stat_site_order\": 130}, {\"site\": 132, \"wildtype\": \"Q\", \"_stat_site_order\": 131}, {\"site\": 133, \"wildtype\": \"F\", \"_stat_site_order\": 132}, {\"site\": 134, \"wildtype\": \"C\", \"_stat_site_order\": 133}, {\"site\": 135, \"wildtype\": \"N\", \"_stat_site_order\": 134}, {\"site\": 136, \"wildtype\": \"D\", \"_stat_site_order\": 135}, {\"site\": 137, \"wildtype\": \"P\", \"_stat_site_order\": 136}, {\"site\": 138, \"wildtype\": \"F\", \"_stat_site_order\": 137}, {\"site\": 139, \"wildtype\": \"L\", \"_stat_site_order\": 138}, {\"site\": 140, \"wildtype\": \"D\", \"_stat_site_order\": 139}, {\"site\": 141, \"wildtype\": \"H\", \"_stat_site_order\": 140}, {\"site\": 142, \"wildtype\": \"K\", \"_stat_site_order\": 141}, {\"site\": 143, \"wildtype\": \"N\", \"_stat_site_order\": 142}, {\"site\": 144, \"wildtype\": \"N\", \"_stat_site_order\": 143}, {\"site\": 145, \"wildtype\": \"K\", \"_stat_site_order\": 144}, {\"site\": 146, \"wildtype\": \"S\", \"_stat_site_order\": 145}, {\"site\": 147, \"wildtype\": \"W\", \"_stat_site_order\": 146}, {\"site\": 148, \"wildtype\": \"M\", \"_stat_site_order\": 147}, {\"site\": 149, \"wildtype\": \"E\", \"_stat_site_order\": 148}, {\"site\": 150, \"wildtype\": \"S\", \"_stat_site_order\": 149}, {\"site\": 151, \"wildtype\": \"E\", \"_stat_site_order\": 150}, {\"site\": 152, \"wildtype\": \"F\", \"_stat_site_order\": 151}, {\"site\": 153, \"wildtype\": \"R\", \"_stat_site_order\": 152}, {\"site\": 154, \"wildtype\": \"V\", \"_stat_site_order\": 153}, {\"site\": 155, \"wildtype\": \"Y\", \"_stat_site_order\": 154}, {\"site\": 156, \"wildtype\": \"S\", \"_stat_site_order\": 155}, {\"site\": 157, \"wildtype\": \"S\", \"_stat_site_order\": 156}, {\"site\": 158, \"wildtype\": \"A\", \"_stat_site_order\": 157}, {\"site\": 159, \"wildtype\": \"N\", \"_stat_site_order\": 158}, {\"site\": 160, \"wildtype\": \"N\", \"_stat_site_order\": 159}, {\"site\": 161, \"wildtype\": \"C\", \"_stat_site_order\": 160}, {\"site\": 162, \"wildtype\": \"T\", \"_stat_site_order\": 161}, {\"site\": 163, \"wildtype\": \"F\", \"_stat_site_order\": 162}, {\"site\": 164, \"wildtype\": \"E\", \"_stat_site_order\": 163}, {\"site\": 165, \"wildtype\": \"Y\", \"_stat_site_order\": 164}, {\"site\": 166, \"wildtype\": \"V\", \"_stat_site_order\": 165}, {\"site\": 167, \"wildtype\": \"S\", \"_stat_site_order\": 166}, {\"site\": 168, \"wildtype\": \"Q\", \"_stat_site_order\": 167}, {\"site\": 169, \"wildtype\": \"P\", \"_stat_site_order\": 168}, {\"site\": 170, \"wildtype\": \"F\", \"_stat_site_order\": 169}, {\"site\": 171, \"wildtype\": \"L\", \"_stat_site_order\": 170}, {\"site\": 172, \"wildtype\": \"M\", \"_stat_site_order\": 171}, {\"site\": 173, \"wildtype\": \"D\", \"_stat_site_order\": 172}, {\"site\": 174, \"wildtype\": \"L\", \"_stat_site_order\": 173}, {\"site\": 175, \"wildtype\": \"E\", \"_stat_site_order\": 174}, {\"site\": 176, \"wildtype\": \"G\", \"_stat_site_order\": 175}, {\"site\": 177, \"wildtype\": \"K\", \"_stat_site_order\": 176}, {\"site\": 178, \"wildtype\": \"Q\", \"_stat_site_order\": 177}, {\"site\": 179, \"wildtype\": \"G\", \"_stat_site_order\": 178}, {\"site\": 180, \"wildtype\": \"N\", \"_stat_site_order\": 179}, {\"site\": 181, \"wildtype\": \"F\", \"_stat_site_order\": 180}, {\"site\": 182, \"wildtype\": \"K\", \"_stat_site_order\": 181}, {\"site\": 183, \"wildtype\": \"N\", \"_stat_site_order\": 182}, {\"site\": 184, \"wildtype\": \"L\", \"_stat_site_order\": 183}, {\"site\": 185, \"wildtype\": \"R\", \"_stat_site_order\": 184}, {\"site\": 186, \"wildtype\": \"E\", \"_stat_site_order\": 185}, {\"site\": 187, \"wildtype\": \"F\", \"_stat_site_order\": 186}, {\"site\": 188, \"wildtype\": \"V\", \"_stat_site_order\": 187}, {\"site\": 189, \"wildtype\": \"F\", \"_stat_site_order\": 188}, {\"site\": 190, \"wildtype\": \"K\", \"_stat_site_order\": 189}, {\"site\": 191, \"wildtype\": \"N\", \"_stat_site_order\": 190}, {\"site\": 192, \"wildtype\": \"I\", \"_stat_site_order\": 191}, {\"site\": 193, \"wildtype\": \"D\", \"_stat_site_order\": 192}, {\"site\": 194, \"wildtype\": \"G\", \"_stat_site_order\": 193}, {\"site\": 195, \"wildtype\": \"Y\", \"_stat_site_order\": 194}, {\"site\": 196, \"wildtype\": \"F\", \"_stat_site_order\": 195}, {\"site\": 197, \"wildtype\": \"K\", \"_stat_site_order\": 196}, {\"site\": 198, \"wildtype\": \"I\", \"_stat_site_order\": 197}, {\"site\": 199, \"wildtype\": \"Y\", \"_stat_site_order\": 198}, {\"site\": 200, \"wildtype\": \"S\", \"_stat_site_order\": 199}, {\"site\": 201, \"wildtype\": \"K\", \"_stat_site_order\": 200}, {\"site\": 202, \"wildtype\": \"H\", \"_stat_site_order\": 201}, {\"site\": 203, \"wildtype\": \"T\", \"_stat_site_order\": 202}, {\"site\": 204, \"wildtype\": \"P\", \"_stat_site_order\": 203}, {\"site\": 205, \"wildtype\": \"I\", \"_stat_site_order\": 204}, {\"site\": 206, \"wildtype\": \"I\", \"_stat_site_order\": 205}, {\"site\": 207, \"wildtype\": \"V\", \"_stat_site_order\": 206}, {\"site\": 208, \"wildtype\": \"R\", \"_stat_site_order\": 207}, {\"site\": 209, \"wildtype\": \"E\", \"_stat_site_order\": 208}, {\"site\": 210, \"wildtype\": \"P\", \"_stat_site_order\": 209}, {\"site\": 211, \"wildtype\": \"E\", \"_stat_site_order\": 210}, {\"site\": 212, \"wildtype\": \"D\", \"_stat_site_order\": 211}, {\"site\": 213, \"wildtype\": \"L\", \"_stat_site_order\": 212}, {\"site\": 214, \"wildtype\": \"P\", \"_stat_site_order\": 213}, {\"site\": 215, \"wildtype\": \"Q\", \"_stat_site_order\": 214}, {\"site\": 216, \"wildtype\": \"G\", \"_stat_site_order\": 215}, {\"site\": 217, \"wildtype\": \"F\", \"_stat_site_order\": 216}, {\"site\": 218, \"wildtype\": \"S\", \"_stat_site_order\": 217}, {\"site\": 219, \"wildtype\": \"A\", \"_stat_site_order\": 218}, {\"site\": 220, \"wildtype\": \"L\", \"_stat_site_order\": 219}, {\"site\": 221, \"wildtype\": \"E\", \"_stat_site_order\": 220}, {\"site\": 222, \"wildtype\": \"P\", \"_stat_site_order\": 221}, {\"site\": 223, \"wildtype\": \"L\", \"_stat_site_order\": 222}, {\"site\": 224, \"wildtype\": \"V\", \"_stat_site_order\": 223}, {\"site\": 225, \"wildtype\": \"D\", \"_stat_site_order\": 224}, {\"site\": 226, \"wildtype\": \"L\", \"_stat_site_order\": 225}, {\"site\": 227, \"wildtype\": \"P\", \"_stat_site_order\": 226}, {\"site\": 228, \"wildtype\": \"I\", \"_stat_site_order\": 227}, {\"site\": 229, \"wildtype\": \"G\", \"_stat_site_order\": 228}, {\"site\": 230, \"wildtype\": \"I\", \"_stat_site_order\": 229}, {\"site\": 231, \"wildtype\": \"N\", \"_stat_site_order\": 230}, {\"site\": 232, \"wildtype\": \"I\", \"_stat_site_order\": 231}, {\"site\": 233, \"wildtype\": \"T\", \"_stat_site_order\": 232}, {\"site\": 234, \"wildtype\": \"R\", \"_stat_site_order\": 233}, {\"site\": 235, \"wildtype\": \"F\", \"_stat_site_order\": 234}, {\"site\": 236, \"wildtype\": \"Q\", \"_stat_site_order\": 235}, {\"site\": 237, \"wildtype\": \"T\", \"_stat_site_order\": 236}, {\"site\": 238, \"wildtype\": \"L\", \"_stat_site_order\": 237}, {\"site\": 239, \"wildtype\": \"L\", \"_stat_site_order\": 238}, {\"site\": 240, \"wildtype\": \"A\", \"_stat_site_order\": 239}, {\"site\": 241, \"wildtype\": \"L\", \"_stat_site_order\": 240}, {\"site\": 242, \"wildtype\": \"H\", \"_stat_site_order\": 241}, {\"site\": 243, \"wildtype\": \"R\", \"_stat_site_order\": 242}, {\"site\": 244, \"wildtype\": \"S\", \"_stat_site_order\": 243}, {\"site\": 245, \"wildtype\": \"Y\", \"_stat_site_order\": 244}, {\"site\": 246, \"wildtype\": \"L\", \"_stat_site_order\": 245}, {\"site\": 247, \"wildtype\": \"T\", \"_stat_site_order\": 246}, {\"site\": 248, \"wildtype\": \"P\", \"_stat_site_order\": 247}, {\"site\": 249, \"wildtype\": \"G\", \"_stat_site_order\": 248}, {\"site\": 250, \"wildtype\": \"D\", \"_stat_site_order\": 249}, {\"site\": 251, \"wildtype\": \"S\", \"_stat_site_order\": 250}, {\"site\": 252, \"wildtype\": \"S\", \"_stat_site_order\": 251}, {\"site\": 253, \"wildtype\": \"S\", \"_stat_site_order\": 252}, {\"site\": 254, \"wildtype\": \"G\", \"_stat_site_order\": 253}, {\"site\": 255, \"wildtype\": \"W\", \"_stat_site_order\": 254}, {\"site\": 256, \"wildtype\": \"T\", \"_stat_site_order\": 255}, {\"site\": 257, \"wildtype\": \"A\", \"_stat_site_order\": 256}, {\"site\": 258, \"wildtype\": \"G\", \"_stat_site_order\": 257}, {\"site\": 259, \"wildtype\": \"A\", \"_stat_site_order\": 258}, {\"site\": 260, \"wildtype\": \"A\", \"_stat_site_order\": 259}, {\"site\": 261, \"wildtype\": \"A\", \"_stat_site_order\": 260}, {\"site\": 262, \"wildtype\": \"Y\", \"_stat_site_order\": 261}, {\"site\": 263, \"wildtype\": \"Y\", \"_stat_site_order\": 262}, {\"site\": 264, \"wildtype\": \"V\", \"_stat_site_order\": 263}, {\"site\": 265, \"wildtype\": \"G\", \"_stat_site_order\": 264}, {\"site\": 266, \"wildtype\": \"Y\", \"_stat_site_order\": 265}, {\"site\": 267, \"wildtype\": \"L\", \"_stat_site_order\": 266}, {\"site\": 268, \"wildtype\": \"Q\", \"_stat_site_order\": 267}, {\"site\": 269, \"wildtype\": \"P\", \"_stat_site_order\": 268}, {\"site\": 270, \"wildtype\": \"R\", \"_stat_site_order\": 269}, {\"site\": 271, \"wildtype\": \"T\", \"_stat_site_order\": 270}, {\"site\": 272, \"wildtype\": \"F\", \"_stat_site_order\": 271}, {\"site\": 273, \"wildtype\": \"L\", \"_stat_site_order\": 272}, {\"site\": 274, \"wildtype\": \"L\", \"_stat_site_order\": 273}, {\"site\": 275, \"wildtype\": \"K\", \"_stat_site_order\": 274}, {\"site\": 276, \"wildtype\": \"Y\", \"_stat_site_order\": 275}, {\"site\": 277, \"wildtype\": \"N\", \"_stat_site_order\": 276}, {\"site\": 278, \"wildtype\": \"E\", \"_stat_site_order\": 277}, {\"site\": 279, \"wildtype\": \"N\", \"_stat_site_order\": 278}, {\"site\": 280, \"wildtype\": \"G\", \"_stat_site_order\": 279}, {\"site\": 281, \"wildtype\": \"T\", \"_stat_site_order\": 280}, {\"site\": 282, \"wildtype\": \"I\", \"_stat_site_order\": 281}, {\"site\": 283, \"wildtype\": \"T\", \"_stat_site_order\": 282}, {\"site\": 284, \"wildtype\": \"D\", \"_stat_site_order\": 283}, {\"site\": 285, \"wildtype\": \"A\", \"_stat_site_order\": 284}, {\"site\": 286, \"wildtype\": \"V\", \"_stat_site_order\": 285}, {\"site\": 287, \"wildtype\": \"D\", \"_stat_site_order\": 286}, {\"site\": 288, \"wildtype\": \"C\", \"_stat_site_order\": 287}, {\"site\": 289, \"wildtype\": \"A\", \"_stat_site_order\": 288}, {\"site\": 290, \"wildtype\": \"L\", \"_stat_site_order\": 289}, {\"site\": 291, \"wildtype\": \"D\", \"_stat_site_order\": 290}, {\"site\": 292, \"wildtype\": \"P\", \"_stat_site_order\": 291}, {\"site\": 293, \"wildtype\": \"L\", \"_stat_site_order\": 292}, {\"site\": 294, \"wildtype\": \"S\", \"_stat_site_order\": 293}, {\"site\": 295, \"wildtype\": \"E\", \"_stat_site_order\": 294}, {\"site\": 296, \"wildtype\": \"T\", \"_stat_site_order\": 295}, {\"site\": 297, \"wildtype\": \"K\", \"_stat_site_order\": 296}, {\"site\": 298, \"wildtype\": \"C\", \"_stat_site_order\": 297}, {\"site\": 299, \"wildtype\": \"T\", \"_stat_site_order\": 298}, {\"site\": 300, \"wildtype\": \"L\", \"_stat_site_order\": 299}, {\"site\": 301, \"wildtype\": \"K\", \"_stat_site_order\": 300}, {\"site\": 302, \"wildtype\": \"S\", \"_stat_site_order\": 301}, {\"site\": 303, \"wildtype\": \"F\", \"_stat_site_order\": 302}, {\"site\": 304, \"wildtype\": \"T\", \"_stat_site_order\": 303}, {\"site\": 305, \"wildtype\": \"V\", \"_stat_site_order\": 304}, {\"site\": 306, \"wildtype\": \"E\", \"_stat_site_order\": 305}, {\"site\": 307, \"wildtype\": \"K\", \"_stat_site_order\": 306}, {\"site\": 308, \"wildtype\": \"G\", \"_stat_site_order\": 307}, {\"site\": 309, \"wildtype\": \"I\", \"_stat_site_order\": 308}, {\"site\": 310, \"wildtype\": \"Y\", \"_stat_site_order\": 309}, {\"site\": 311, \"wildtype\": \"Q\", \"_stat_site_order\": 310}, {\"site\": 312, \"wildtype\": \"T\", \"_stat_site_order\": 311}, {\"site\": 313, \"wildtype\": \"S\", \"_stat_site_order\": 312}, {\"site\": 314, \"wildtype\": \"N\", \"_stat_site_order\": 313}, {\"site\": 315, \"wildtype\": \"F\", \"_stat_site_order\": 314}, {\"site\": 316, \"wildtype\": \"R\", \"_stat_site_order\": 315}, {\"site\": 317, \"wildtype\": \"V\", \"_stat_site_order\": 316}, {\"site\": 318, \"wildtype\": \"Q\", \"_stat_site_order\": 317}, {\"site\": 319, \"wildtype\": \"P\", \"_stat_site_order\": 318}, {\"site\": 320, \"wildtype\": \"T\", \"_stat_site_order\": 319}, {\"site\": 321, \"wildtype\": \"E\", \"_stat_site_order\": 320}, {\"site\": 322, \"wildtype\": \"S\", \"_stat_site_order\": 321}, {\"site\": 323, \"wildtype\": \"I\", \"_stat_site_order\": 322}, {\"site\": 324, \"wildtype\": \"V\", \"_stat_site_order\": 323}, {\"site\": 325, \"wildtype\": \"R\", \"_stat_site_order\": 324}, {\"site\": 326, \"wildtype\": \"F\", \"_stat_site_order\": 325}, {\"site\": 327, \"wildtype\": \"P\", \"_stat_site_order\": 326}, {\"site\": 328, \"wildtype\": \"N\", \"_stat_site_order\": 327}, {\"site\": 329, \"wildtype\": \"I\", \"_stat_site_order\": 328}, {\"site\": 330, \"wildtype\": \"T\", \"_stat_site_order\": 329}, {\"site\": 331, \"wildtype\": \"N\", \"_stat_site_order\": 330}, {\"site\": 332, \"wildtype\": \"L\", \"_stat_site_order\": 331}, {\"site\": 333, \"wildtype\": \"C\", \"_stat_site_order\": 332}, {\"site\": 334, \"wildtype\": \"P\", \"_stat_site_order\": 333}, {\"site\": 335, \"wildtype\": \"F\", \"_stat_site_order\": 334}, {\"site\": 336, \"wildtype\": \"D\", \"_stat_site_order\": 335}, {\"site\": 337, \"wildtype\": \"E\", \"_stat_site_order\": 336}, {\"site\": 338, \"wildtype\": \"V\", \"_stat_site_order\": 337}, {\"site\": 339, \"wildtype\": \"F\", \"_stat_site_order\": 338}, {\"site\": 340, \"wildtype\": \"N\", \"_stat_site_order\": 339}, {\"site\": 341, \"wildtype\": \"A\", \"_stat_site_order\": 340}, {\"site\": 342, \"wildtype\": \"T\", \"_stat_site_order\": 341}, {\"site\": 343, \"wildtype\": \"R\", \"_stat_site_order\": 342}, {\"site\": 345, \"wildtype\": \"A\", \"_stat_site_order\": 343}, {\"site\": 346, \"wildtype\": \"S\", \"_stat_site_order\": 344}, {\"site\": 347, \"wildtype\": \"V\", \"_stat_site_order\": 345}, {\"site\": 348, \"wildtype\": \"Y\", \"_stat_site_order\": 346}, {\"site\": 349, \"wildtype\": \"A\", \"_stat_site_order\": 347}, {\"site\": 350, \"wildtype\": \"W\", \"_stat_site_order\": 348}, {\"site\": 351, \"wildtype\": \"N\", \"_stat_site_order\": 349}, {\"site\": 352, \"wildtype\": \"R\", \"_stat_site_order\": 350}, {\"site\": 353, \"wildtype\": \"K\", \"_stat_site_order\": 351}, {\"site\": 354, \"wildtype\": \"R\", \"_stat_site_order\": 352}, {\"site\": 355, \"wildtype\": \"I\", \"_stat_site_order\": 353}, {\"site\": 356, \"wildtype\": \"S\", \"_stat_site_order\": 354}, {\"site\": 357, \"wildtype\": \"N\", \"_stat_site_order\": 355}, {\"site\": 358, \"wildtype\": \"C\", \"_stat_site_order\": 356}, {\"site\": 359, \"wildtype\": \"V\", \"_stat_site_order\": 357}, {\"site\": 360, \"wildtype\": \"A\", \"_stat_site_order\": 358}, {\"site\": 361, \"wildtype\": \"D\", \"_stat_site_order\": 359}, {\"site\": 362, \"wildtype\": \"Y\", \"_stat_site_order\": 360}, {\"site\": 363, \"wildtype\": \"S\", \"_stat_site_order\": 361}, {\"site\": 364, \"wildtype\": \"V\", \"_stat_site_order\": 362}, {\"site\": 365, \"wildtype\": \"L\", \"_stat_site_order\": 363}, {\"site\": 366, \"wildtype\": \"Y\", \"_stat_site_order\": 364}, {\"site\": 367, \"wildtype\": \"N\", \"_stat_site_order\": 365}, {\"site\": 368, \"wildtype\": \"L\", \"_stat_site_order\": 366}, {\"site\": 369, \"wildtype\": \"A\", \"_stat_site_order\": 367}, {\"site\": 370, \"wildtype\": \"P\", \"_stat_site_order\": 368}, {\"site\": 371, \"wildtype\": \"F\", \"_stat_site_order\": 369}, {\"site\": 372, \"wildtype\": \"F\", \"_stat_site_order\": 370}, {\"site\": 373, \"wildtype\": \"T\", \"_stat_site_order\": 371}, {\"site\": 374, \"wildtype\": \"F\", \"_stat_site_order\": 372}, {\"site\": 375, \"wildtype\": \"K\", \"_stat_site_order\": 373}, {\"site\": 376, \"wildtype\": \"C\", \"_stat_site_order\": 374}, {\"site\": 377, \"wildtype\": \"Y\", \"_stat_site_order\": 375}, {\"site\": 378, \"wildtype\": \"G\", \"_stat_site_order\": 376}, {\"site\": 379, \"wildtype\": \"V\", \"_stat_site_order\": 377}, {\"site\": 380, \"wildtype\": \"S\", \"_stat_site_order\": 378}, {\"site\": 381, \"wildtype\": \"P\", \"_stat_site_order\": 379}, {\"site\": 382, \"wildtype\": \"T\", \"_stat_site_order\": 380}, {\"site\": 383, \"wildtype\": \"K\", \"_stat_site_order\": 381}, {\"site\": 384, \"wildtype\": \"L\", \"_stat_site_order\": 382}, {\"site\": 385, \"wildtype\": \"N\", \"_stat_site_order\": 383}, {\"site\": 386, \"wildtype\": \"D\", \"_stat_site_order\": 384}, {\"site\": 387, \"wildtype\": \"L\", \"_stat_site_order\": 385}, {\"site\": 388, \"wildtype\": \"C\", \"_stat_site_order\": 386}, {\"site\": 389, \"wildtype\": \"F\", \"_stat_site_order\": 387}, {\"site\": 390, \"wildtype\": \"T\", \"_stat_site_order\": 388}, {\"site\": 391, \"wildtype\": \"N\", \"_stat_site_order\": 389}, {\"site\": 392, \"wildtype\": \"V\", \"_stat_site_order\": 390}, {\"site\": 393, \"wildtype\": \"Y\", \"_stat_site_order\": 391}, {\"site\": 394, \"wildtype\": \"A\", \"_stat_site_order\": 392}, {\"site\": 395, \"wildtype\": \"D\", \"_stat_site_order\": 393}, {\"site\": 396, \"wildtype\": \"S\", \"_stat_site_order\": 394}, {\"site\": 397, \"wildtype\": \"F\", \"_stat_site_order\": 395}, {\"site\": 398, \"wildtype\": \"V\", \"_stat_site_order\": 396}, {\"site\": 399, \"wildtype\": \"I\", \"_stat_site_order\": 397}, {\"site\": 400, \"wildtype\": \"R\", \"_stat_site_order\": 398}, {\"site\": 401, \"wildtype\": \"G\", \"_stat_site_order\": 399}, {\"site\": 402, \"wildtype\": \"D\", \"_stat_site_order\": 400}, {\"site\": 403, \"wildtype\": \"E\", \"_stat_site_order\": 401}, {\"site\": 404, \"wildtype\": \"V\", \"_stat_site_order\": 402}, {\"site\": 405, \"wildtype\": \"R\", \"_stat_site_order\": 403}, {\"site\": 406, \"wildtype\": \"Q\", \"_stat_site_order\": 404}, {\"site\": 407, \"wildtype\": \"I\", \"_stat_site_order\": 405}, {\"site\": 408, \"wildtype\": \"A\", \"_stat_site_order\": 406}, {\"site\": 409, \"wildtype\": \"P\", \"_stat_site_order\": 407}, {\"site\": 410, \"wildtype\": \"G\", \"_stat_site_order\": 408}, {\"site\": 411, \"wildtype\": \"Q\", \"_stat_site_order\": 409}, {\"site\": 412, \"wildtype\": \"T\", \"_stat_site_order\": 410}, {\"site\": 413, \"wildtype\": \"G\", \"_stat_site_order\": 411}, {\"site\": 414, \"wildtype\": \"N\", \"_stat_site_order\": 412}, {\"site\": 415, \"wildtype\": \"I\", \"_stat_site_order\": 413}, {\"site\": 416, \"wildtype\": \"A\", \"_stat_site_order\": 414}, {\"site\": 417, \"wildtype\": \"D\", \"_stat_site_order\": 415}, {\"site\": 418, \"wildtype\": \"Y\", \"_stat_site_order\": 416}, {\"site\": 419, \"wildtype\": \"N\", \"_stat_site_order\": 417}, {\"site\": 420, \"wildtype\": \"Y\", \"_stat_site_order\": 418}, {\"site\": 421, \"wildtype\": \"K\", \"_stat_site_order\": 419}, {\"site\": 422, \"wildtype\": \"L\", \"_stat_site_order\": 420}, {\"site\": 423, \"wildtype\": \"P\", \"_stat_site_order\": 421}, {\"site\": 424, \"wildtype\": \"D\", \"_stat_site_order\": 422}, {\"site\": 425, \"wildtype\": \"D\", \"_stat_site_order\": 423}, {\"site\": 426, \"wildtype\": \"F\", \"_stat_site_order\": 424}, {\"site\": 427, \"wildtype\": \"T\", \"_stat_site_order\": 425}, {\"site\": 428, \"wildtype\": \"G\", \"_stat_site_order\": 426}, {\"site\": 429, \"wildtype\": \"C\", \"_stat_site_order\": 427}, {\"site\": 430, \"wildtype\": \"V\", \"_stat_site_order\": 428}, {\"site\": 431, \"wildtype\": \"I\", \"_stat_site_order\": 429}, {\"site\": 432, \"wildtype\": \"A\", \"_stat_site_order\": 430}, {\"site\": 433, \"wildtype\": \"W\", \"_stat_site_order\": 431}, {\"site\": 434, \"wildtype\": \"N\", \"_stat_site_order\": 432}, {\"site\": 435, \"wildtype\": \"S\", \"_stat_site_order\": 433}, {\"site\": 436, \"wildtype\": \"N\", \"_stat_site_order\": 434}, {\"site\": 437, \"wildtype\": \"K\", \"_stat_site_order\": 435}, {\"site\": 438, \"wildtype\": \"L\", \"_stat_site_order\": 436}, {\"site\": 439, \"wildtype\": \"D\", \"_stat_site_order\": 437}, {\"site\": 440, \"wildtype\": \"S\", \"_stat_site_order\": 438}, {\"site\": 441, \"wildtype\": \"K\", \"_stat_site_order\": 439}, {\"site\": 442, \"wildtype\": \"V\", \"_stat_site_order\": 440}, {\"site\": 443, \"wildtype\": \"S\", \"_stat_site_order\": 441}, {\"site\": 444, \"wildtype\": \"G\", \"_stat_site_order\": 442}, {\"site\": 445, \"wildtype\": \"N\", \"_stat_site_order\": 443}, {\"site\": 446, \"wildtype\": \"Y\", \"_stat_site_order\": 444}, {\"site\": 447, \"wildtype\": \"N\", \"_stat_site_order\": 445}, {\"site\": 448, \"wildtype\": \"Y\", \"_stat_site_order\": 446}, {\"site\": 449, \"wildtype\": \"L\", \"_stat_site_order\": 447}, {\"site\": 450, \"wildtype\": \"Y\", \"_stat_site_order\": 448}, {\"site\": 451, \"wildtype\": \"R\", \"_stat_site_order\": 449}, {\"site\": 452, \"wildtype\": \"L\", \"_stat_site_order\": 450}, {\"site\": 453, \"wildtype\": \"F\", \"_stat_site_order\": 451}, {\"site\": 454, \"wildtype\": \"R\", \"_stat_site_order\": 452}, {\"site\": 455, \"wildtype\": \"K\", \"_stat_site_order\": 453}, {\"site\": 456, \"wildtype\": \"S\", \"_stat_site_order\": 454}, {\"site\": 457, \"wildtype\": \"N\", \"_stat_site_order\": 455}, {\"site\": 458, \"wildtype\": \"L\", \"_stat_site_order\": 456}, {\"site\": 459, \"wildtype\": \"K\", \"_stat_site_order\": 457}, {\"site\": 460, \"wildtype\": \"P\", \"_stat_site_order\": 458}, {\"site\": 461, \"wildtype\": \"F\", \"_stat_site_order\": 459}, {\"site\": 462, \"wildtype\": \"E\", \"_stat_site_order\": 460}, {\"site\": 463, \"wildtype\": \"R\", \"_stat_site_order\": 461}, {\"site\": 464, \"wildtype\": \"D\", \"_stat_site_order\": 462}, {\"site\": 465, \"wildtype\": \"I\", \"_stat_site_order\": 463}, {\"site\": 466, \"wildtype\": \"S\", \"_stat_site_order\": 464}, {\"site\": 467, \"wildtype\": \"T\", \"_stat_site_order\": 465}, {\"site\": 468, \"wildtype\": \"E\", \"_stat_site_order\": 466}, {\"site\": 469, \"wildtype\": \"I\", \"_stat_site_order\": 467}, {\"site\": 470, \"wildtype\": \"Y\", \"_stat_site_order\": 468}, {\"site\": 471, \"wildtype\": \"Q\", \"_stat_site_order\": 469}, {\"site\": 472, \"wildtype\": \"A\", \"_stat_site_order\": 470}, {\"site\": 473, \"wildtype\": \"G\", \"_stat_site_order\": 471}, {\"site\": 474, \"wildtype\": \"N\", \"_stat_site_order\": 472}, {\"site\": 475, \"wildtype\": \"K\", \"_stat_site_order\": 473}, {\"site\": 476, \"wildtype\": \"P\", \"_stat_site_order\": 474}, {\"site\": 477, \"wildtype\": \"C\", \"_stat_site_order\": 475}, {\"site\": 478, \"wildtype\": \"N\", \"_stat_site_order\": 476}, {\"site\": 479, \"wildtype\": \"G\", \"_stat_site_order\": 477}, {\"site\": 480, \"wildtype\": \"V\", \"_stat_site_order\": 478}, {\"site\": 481, \"wildtype\": \"A\", \"_stat_site_order\": 479}, {\"site\": 482, \"wildtype\": \"G\", \"_stat_site_order\": 480}, {\"site\": 483, \"wildtype\": \"F\", \"_stat_site_order\": 481}, {\"site\": 484, \"wildtype\": \"N\", \"_stat_site_order\": 482}, {\"site\": 485, \"wildtype\": \"C\", \"_stat_site_order\": 483}, {\"site\": 486, \"wildtype\": \"Y\", \"_stat_site_order\": 484}, {\"site\": 487, \"wildtype\": \"F\", \"_stat_site_order\": 485}, {\"site\": 488, \"wildtype\": \"P\", \"_stat_site_order\": 486}, {\"site\": 489, \"wildtype\": \"L\", \"_stat_site_order\": 487}, {\"site\": 490, \"wildtype\": \"R\", \"_stat_site_order\": 488}, {\"site\": 491, \"wildtype\": \"S\", \"_stat_site_order\": 489}, {\"site\": 492, \"wildtype\": \"Y\", \"_stat_site_order\": 490}, {\"site\": 493, \"wildtype\": \"S\", \"_stat_site_order\": 491}, {\"site\": 494, \"wildtype\": \"F\", \"_stat_site_order\": 492}, {\"site\": 495, \"wildtype\": \"R\", \"_stat_site_order\": 493}, {\"site\": 496, \"wildtype\": \"P\", \"_stat_site_order\": 494}, {\"site\": 497, \"wildtype\": \"T\", \"_stat_site_order\": 495}, {\"site\": 498, \"wildtype\": \"Y\", \"_stat_site_order\": 496}, {\"site\": 499, \"wildtype\": \"G\", \"_stat_site_order\": 497}, {\"site\": 500, \"wildtype\": \"V\", \"_stat_site_order\": 498}, {\"site\": 501, \"wildtype\": \"G\", \"_stat_site_order\": 499}, {\"site\": 502, \"wildtype\": \"H\", \"_stat_site_order\": 500}, {\"site\": 503, \"wildtype\": \"Q\", \"_stat_site_order\": 501}, {\"site\": 504, \"wildtype\": \"P\", \"_stat_site_order\": 502}, {\"site\": 505, \"wildtype\": \"Y\", \"_stat_site_order\": 503}, {\"site\": 506, \"wildtype\": \"R\", \"_stat_site_order\": 504}, {\"site\": 507, \"wildtype\": \"V\", \"_stat_site_order\": 505}, {\"site\": 508, \"wildtype\": \"V\", \"_stat_site_order\": 506}, {\"site\": 509, \"wildtype\": \"V\", \"_stat_site_order\": 507}, {\"site\": 510, \"wildtype\": \"L\", \"_stat_site_order\": 508}, {\"site\": 511, \"wildtype\": \"S\", \"_stat_site_order\": 509}, {\"site\": 512, \"wildtype\": \"F\", \"_stat_site_order\": 510}, {\"site\": 513, \"wildtype\": \"E\", \"_stat_site_order\": 511}, {\"site\": 514, \"wildtype\": \"L\", \"_stat_site_order\": 512}, {\"site\": 515, \"wildtype\": \"L\", \"_stat_site_order\": 513}, {\"site\": 516, \"wildtype\": \"H\", \"_stat_site_order\": 514}, {\"site\": 517, \"wildtype\": \"A\", \"_stat_site_order\": 515}, {\"site\": 518, \"wildtype\": \"P\", \"_stat_site_order\": 516}, {\"site\": 519, \"wildtype\": \"A\", \"_stat_site_order\": 517}, {\"site\": 520, \"wildtype\": \"T\", \"_stat_site_order\": 518}, {\"site\": 521, \"wildtype\": \"V\", \"_stat_site_order\": 519}, {\"site\": 522, \"wildtype\": \"C\", \"_stat_site_order\": 520}, {\"site\": 523, \"wildtype\": \"G\", \"_stat_site_order\": 521}, {\"site\": 524, \"wildtype\": \"P\", \"_stat_site_order\": 522}, {\"site\": 525, \"wildtype\": \"K\", \"_stat_site_order\": 523}, {\"site\": 526, \"wildtype\": \"K\", \"_stat_site_order\": 524}, {\"site\": 527, \"wildtype\": \"S\", \"_stat_site_order\": 525}, {\"site\": 528, \"wildtype\": \"T\", \"_stat_site_order\": 526}, {\"site\": 529, \"wildtype\": \"N\", \"_stat_site_order\": 527}, {\"site\": 530, \"wildtype\": \"L\", \"_stat_site_order\": 528}, {\"site\": 531, \"wildtype\": \"V\", \"_stat_site_order\": 529}, {\"site\": 532, \"wildtype\": \"K\", \"_stat_site_order\": 530}, {\"site\": 533, \"wildtype\": \"N\", \"_stat_site_order\": 531}, {\"site\": 534, \"wildtype\": \"K\", \"_stat_site_order\": 532}, {\"site\": 535, \"wildtype\": \"C\", \"_stat_site_order\": 533}, {\"site\": 536, \"wildtype\": \"V\", \"_stat_site_order\": 534}, {\"site\": 537, \"wildtype\": \"N\", \"_stat_site_order\": 535}, {\"site\": 538, \"wildtype\": \"F\", \"_stat_site_order\": 536}, {\"site\": 539, \"wildtype\": \"N\", \"_stat_site_order\": 537}, {\"site\": 540, \"wildtype\": \"F\", \"_stat_site_order\": 538}, {\"site\": 541, \"wildtype\": \"N\", \"_stat_site_order\": 539}, {\"site\": 542, \"wildtype\": \"G\", \"_stat_site_order\": 540}, {\"site\": 543, \"wildtype\": \"L\", \"_stat_site_order\": 541}, {\"site\": 544, \"wildtype\": \"K\", \"_stat_site_order\": 542}, {\"site\": 545, \"wildtype\": \"G\", \"_stat_site_order\": 543}, {\"site\": 546, \"wildtype\": \"T\", \"_stat_site_order\": 544}, {\"site\": 547, \"wildtype\": \"G\", \"_stat_site_order\": 545}, {\"site\": 548, \"wildtype\": \"V\", \"_stat_site_order\": 546}, {\"site\": 549, \"wildtype\": \"L\", \"_stat_site_order\": 547}, {\"site\": 550, \"wildtype\": \"T\", \"_stat_site_order\": 548}, {\"site\": 551, \"wildtype\": \"E\", \"_stat_site_order\": 549}, {\"site\": 552, \"wildtype\": \"S\", \"_stat_site_order\": 550}, {\"site\": 553, \"wildtype\": \"N\", \"_stat_site_order\": 551}, {\"site\": 554, \"wildtype\": \"K\", \"_stat_site_order\": 552}, {\"site\": 555, \"wildtype\": \"K\", \"_stat_site_order\": 553}, {\"site\": 556, \"wildtype\": \"F\", \"_stat_site_order\": 554}, {\"site\": 557, \"wildtype\": \"L\", \"_stat_site_order\": 555}, {\"site\": 558, \"wildtype\": \"P\", \"_stat_site_order\": 556}, {\"site\": 559, \"wildtype\": \"F\", \"_stat_site_order\": 557}, {\"site\": 560, \"wildtype\": \"Q\", \"_stat_site_order\": 558}, {\"site\": 561, \"wildtype\": \"Q\", \"_stat_site_order\": 559}, {\"site\": 562, \"wildtype\": \"F\", \"_stat_site_order\": 560}, {\"site\": 563, \"wildtype\": \"G\", \"_stat_site_order\": 561}, {\"site\": 564, \"wildtype\": \"R\", \"_stat_site_order\": 562}, {\"site\": 565, \"wildtype\": \"D\", \"_stat_site_order\": 563}, {\"site\": 566, \"wildtype\": \"I\", \"_stat_site_order\": 564}, {\"site\": 567, \"wildtype\": \"A\", \"_stat_site_order\": 565}, {\"site\": 568, \"wildtype\": \"D\", \"_stat_site_order\": 566}, {\"site\": 569, \"wildtype\": \"T\", \"_stat_site_order\": 567}, {\"site\": 570, \"wildtype\": \"T\", \"_stat_site_order\": 568}, {\"site\": 571, \"wildtype\": \"D\", \"_stat_site_order\": 569}, {\"site\": 572, \"wildtype\": \"A\", \"_stat_site_order\": 570}, {\"site\": 573, \"wildtype\": \"V\", \"_stat_site_order\": 571}, {\"site\": 574, \"wildtype\": \"R\", \"_stat_site_order\": 572}, {\"site\": 575, \"wildtype\": \"D\", \"_stat_site_order\": 573}, {\"site\": 576, \"wildtype\": \"P\", \"_stat_site_order\": 574}, {\"site\": 577, \"wildtype\": \"Q\", \"_stat_site_order\": 575}, {\"site\": 578, \"wildtype\": \"T\", \"_stat_site_order\": 576}, {\"site\": 579, \"wildtype\": \"L\", \"_stat_site_order\": 577}, {\"site\": 580, \"wildtype\": \"E\", \"_stat_site_order\": 578}, {\"site\": 581, \"wildtype\": \"I\", \"_stat_site_order\": 579}, {\"site\": 582, \"wildtype\": \"L\", \"_stat_site_order\": 580}, {\"site\": 583, \"wildtype\": \"D\", \"_stat_site_order\": 581}, {\"site\": 584, \"wildtype\": \"I\", \"_stat_site_order\": 582}, {\"site\": 585, \"wildtype\": \"T\", \"_stat_site_order\": 583}, {\"site\": 586, \"wildtype\": \"P\", \"_stat_site_order\": 584}, {\"site\": 587, \"wildtype\": \"C\", \"_stat_site_order\": 585}, {\"site\": 588, \"wildtype\": \"S\", \"_stat_site_order\": 586}, {\"site\": 589, \"wildtype\": \"F\", \"_stat_site_order\": 587}, {\"site\": 590, \"wildtype\": \"G\", \"_stat_site_order\": 588}, {\"site\": 591, \"wildtype\": \"G\", \"_stat_site_order\": 589}, {\"site\": 592, \"wildtype\": \"V\", \"_stat_site_order\": 590}, {\"site\": 593, \"wildtype\": \"S\", \"_stat_site_order\": 591}, {\"site\": 594, \"wildtype\": \"V\", \"_stat_site_order\": 592}, {\"site\": 595, \"wildtype\": \"I\", \"_stat_site_order\": 593}, {\"site\": 596, \"wildtype\": \"T\", \"_stat_site_order\": 594}, {\"site\": 597, \"wildtype\": \"P\", \"_stat_site_order\": 595}, {\"site\": 598, \"wildtype\": \"G\", \"_stat_site_order\": 596}, {\"site\": 599, \"wildtype\": \"T\", \"_stat_site_order\": 597}, {\"site\": 600, \"wildtype\": \"N\", \"_stat_site_order\": 598}, {\"site\": 601, \"wildtype\": \"T\", \"_stat_site_order\": 599}, {\"site\": 602, \"wildtype\": \"S\", \"_stat_site_order\": 600}, {\"site\": 603, \"wildtype\": \"N\", \"_stat_site_order\": 601}, {\"site\": 604, \"wildtype\": \"Q\", \"_stat_site_order\": 602}, {\"site\": 605, \"wildtype\": \"V\", \"_stat_site_order\": 603}, {\"site\": 606, \"wildtype\": \"A\", \"_stat_site_order\": 604}, {\"site\": 607, \"wildtype\": \"V\", \"_stat_site_order\": 605}, {\"site\": 608, \"wildtype\": \"L\", \"_stat_site_order\": 606}, {\"site\": 609, \"wildtype\": \"Y\", \"_stat_site_order\": 607}, {\"site\": 610, \"wildtype\": \"Q\", \"_stat_site_order\": 608}, {\"site\": 611, \"wildtype\": \"G\", \"_stat_site_order\": 609}, {\"site\": 612, \"wildtype\": \"V\", \"_stat_site_order\": 610}, {\"site\": 613, \"wildtype\": \"N\", \"_stat_site_order\": 611}, {\"site\": 614, \"wildtype\": \"C\", \"_stat_site_order\": 612}, {\"site\": 615, \"wildtype\": \"T\", \"_stat_site_order\": 613}, {\"site\": 616, \"wildtype\": \"E\", \"_stat_site_order\": 614}, {\"site\": 617, \"wildtype\": \"V\", \"_stat_site_order\": 615}, {\"site\": 618, \"wildtype\": \"P\", \"_stat_site_order\": 616}, {\"site\": 619, \"wildtype\": \"V\", \"_stat_site_order\": 617}, {\"site\": 620, \"wildtype\": \"A\", \"_stat_site_order\": 618}, {\"site\": 621, \"wildtype\": \"I\", \"_stat_site_order\": 619}, {\"site\": 622, \"wildtype\": \"H\", \"_stat_site_order\": 620}, {\"site\": 623, \"wildtype\": \"A\", \"_stat_site_order\": 621}, {\"site\": 624, \"wildtype\": \"D\", \"_stat_site_order\": 622}, {\"site\": 625, \"wildtype\": \"Q\", \"_stat_site_order\": 623}, {\"site\": 626, \"wildtype\": \"L\", \"_stat_site_order\": 624}, {\"site\": 627, \"wildtype\": \"T\", \"_stat_site_order\": 625}, {\"site\": 628, \"wildtype\": \"P\", \"_stat_site_order\": 626}, {\"site\": 629, \"wildtype\": \"T\", \"_stat_site_order\": 627}, {\"site\": 630, \"wildtype\": \"W\", \"_stat_site_order\": 628}, {\"site\": 631, \"wildtype\": \"R\", \"_stat_site_order\": 629}, {\"site\": 632, \"wildtype\": \"V\", \"_stat_site_order\": 630}, {\"site\": 633, \"wildtype\": \"Y\", \"_stat_site_order\": 631}, {\"site\": 634, \"wildtype\": \"S\", \"_stat_site_order\": 632}, {\"site\": 635, \"wildtype\": \"T\", \"_stat_site_order\": 633}, {\"site\": 636, \"wildtype\": \"G\", \"_stat_site_order\": 634}, {\"site\": 637, \"wildtype\": \"S\", \"_stat_site_order\": 635}, {\"site\": 638, \"wildtype\": \"N\", \"_stat_site_order\": 636}, {\"site\": 639, \"wildtype\": \"V\", \"_stat_site_order\": 637}, {\"site\": 640, \"wildtype\": \"F\", \"_stat_site_order\": 638}, {\"site\": 641, \"wildtype\": \"Q\", \"_stat_site_order\": 639}, {\"site\": 642, \"wildtype\": \"T\", \"_stat_site_order\": 640}, {\"site\": 643, \"wildtype\": \"R\", \"_stat_site_order\": 641}, {\"site\": 644, \"wildtype\": \"A\", \"_stat_site_order\": 642}, {\"site\": 645, \"wildtype\": \"G\", \"_stat_site_order\": 643}, {\"site\": 646, \"wildtype\": \"C\", \"_stat_site_order\": 644}, {\"site\": 647, \"wildtype\": \"L\", \"_stat_site_order\": 645}, {\"site\": 648, \"wildtype\": \"I\", \"_stat_site_order\": 646}, {\"site\": 649, \"wildtype\": \"G\", \"_stat_site_order\": 647}, {\"site\": 650, \"wildtype\": \"A\", \"_stat_site_order\": 648}, {\"site\": 651, \"wildtype\": \"E\", \"_stat_site_order\": 649}, {\"site\": 652, \"wildtype\": \"Y\", \"_stat_site_order\": 650}, {\"site\": 653, \"wildtype\": \"V\", \"_stat_site_order\": 651}, {\"site\": 654, \"wildtype\": \"N\", \"_stat_site_order\": 652}, {\"site\": 655, \"wildtype\": \"N\", \"_stat_site_order\": 653}, {\"site\": 656, \"wildtype\": \"S\", \"_stat_site_order\": 654}, {\"site\": 657, \"wildtype\": \"Y\", \"_stat_site_order\": 655}, {\"site\": 658, \"wildtype\": \"E\", \"_stat_site_order\": 656}, {\"site\": 659, \"wildtype\": \"C\", \"_stat_site_order\": 657}, {\"site\": 660, \"wildtype\": \"D\", \"_stat_site_order\": 658}, {\"site\": 661, \"wildtype\": \"I\", \"_stat_site_order\": 659}, {\"site\": 662, \"wildtype\": \"P\", \"_stat_site_order\": 660}, {\"site\": 663, \"wildtype\": \"I\", \"_stat_site_order\": 661}, {\"site\": 664, \"wildtype\": \"G\", \"_stat_site_order\": 662}, {\"site\": 665, \"wildtype\": \"A\", \"_stat_site_order\": 663}, {\"site\": 666, \"wildtype\": \"G\", \"_stat_site_order\": 664}, {\"site\": 667, \"wildtype\": \"I\", \"_stat_site_order\": 665}, {\"site\": 668, \"wildtype\": \"C\", \"_stat_site_order\": 666}, {\"site\": 669, \"wildtype\": \"A\", \"_stat_site_order\": 667}, {\"site\": 670, \"wildtype\": \"S\", \"_stat_site_order\": 668}, {\"site\": 671, \"wildtype\": \"Y\", \"_stat_site_order\": 669}, {\"site\": 672, \"wildtype\": \"Q\", \"_stat_site_order\": 670}, {\"site\": 673, \"wildtype\": \"T\", \"_stat_site_order\": 671}, {\"site\": 674, \"wildtype\": \"Q\", \"_stat_site_order\": 672}, {\"site\": 675, \"wildtype\": \"T\", \"_stat_site_order\": 673}, {\"site\": 676, \"wildtype\": \"K\", \"_stat_site_order\": 674}, {\"site\": 677, \"wildtype\": \"S\", \"_stat_site_order\": 675}, {\"site\": 678, \"wildtype\": \"H\", \"_stat_site_order\": 676}, {\"site\": 679, \"wildtype\": \"R\", \"_stat_site_order\": 677}, {\"site\": 680, \"wildtype\": \"R\", \"_stat_site_order\": 678}, {\"site\": 681, \"wildtype\": \"A\", \"_stat_site_order\": 679}, {\"site\": 682, \"wildtype\": \"R\", \"_stat_site_order\": 680}, {\"site\": 683, \"wildtype\": \"S\", \"_stat_site_order\": 681}, {\"site\": 684, \"wildtype\": \"V\", \"_stat_site_order\": 682}, {\"site\": 685, \"wildtype\": \"A\", \"_stat_site_order\": 683}, {\"site\": 686, \"wildtype\": \"S\", \"_stat_site_order\": 684}, {\"site\": 687, \"wildtype\": \"Q\", \"_stat_site_order\": 685}, {\"site\": 688, \"wildtype\": \"S\", \"_stat_site_order\": 686}, {\"site\": 689, \"wildtype\": \"I\", \"_stat_site_order\": 687}, {\"site\": 690, \"wildtype\": \"I\", \"_stat_site_order\": 688}, {\"site\": 691, \"wildtype\": \"A\", \"_stat_site_order\": 689}, {\"site\": 693, \"wildtype\": \"T\", \"_stat_site_order\": 690}, {\"site\": 694, \"wildtype\": \"M\", \"_stat_site_order\": 691}, {\"site\": 695, \"wildtype\": \"S\", \"_stat_site_order\": 692}, {\"site\": 696, \"wildtype\": \"L\", \"_stat_site_order\": 693}, {\"site\": 697, \"wildtype\": \"G\", \"_stat_site_order\": 694}, {\"site\": 698, \"wildtype\": \"A\", \"_stat_site_order\": 695}, {\"site\": 699, \"wildtype\": \"E\", \"_stat_site_order\": 696}, {\"site\": 700, \"wildtype\": \"N\", \"_stat_site_order\": 697}, {\"site\": 701, \"wildtype\": \"S\", \"_stat_site_order\": 698}, {\"site\": 702, \"wildtype\": \"V\", \"_stat_site_order\": 699}, {\"site\": 703, \"wildtype\": \"A\", \"_stat_site_order\": 700}, {\"site\": 704, \"wildtype\": \"Y\", \"_stat_site_order\": 701}, {\"site\": 705, \"wildtype\": \"S\", \"_stat_site_order\": 702}, {\"site\": 706, \"wildtype\": \"N\", \"_stat_site_order\": 703}, {\"site\": 707, \"wildtype\": \"N\", \"_stat_site_order\": 704}, {\"site\": 708, \"wildtype\": \"S\", \"_stat_site_order\": 705}, {\"site\": 709, \"wildtype\": \"I\", \"_stat_site_order\": 706}, {\"site\": 710, \"wildtype\": \"A\", \"_stat_site_order\": 707}, {\"site\": 711, \"wildtype\": \"I\", \"_stat_site_order\": 708}, {\"site\": 712, \"wildtype\": \"P\", \"_stat_site_order\": 709}, {\"site\": 713, \"wildtype\": \"T\", \"_stat_site_order\": 710}, {\"site\": 714, \"wildtype\": \"N\", \"_stat_site_order\": 711}, {\"site\": 715, \"wildtype\": \"F\", \"_stat_site_order\": 712}, {\"site\": 716, \"wildtype\": \"T\", \"_stat_site_order\": 713}, {\"site\": 717, \"wildtype\": \"I\", \"_stat_site_order\": 714}, {\"site\": 718, \"wildtype\": \"S\", \"_stat_site_order\": 715}, {\"site\": 719, \"wildtype\": \"V\", \"_stat_site_order\": 716}, {\"site\": 720, \"wildtype\": \"T\", \"_stat_site_order\": 717}, {\"site\": 721, \"wildtype\": \"T\", \"_stat_site_order\": 718}, {\"site\": 722, \"wildtype\": \"E\", \"_stat_site_order\": 719}, {\"site\": 723, \"wildtype\": \"I\", \"_stat_site_order\": 720}, {\"site\": 724, \"wildtype\": \"L\", \"_stat_site_order\": 721}, {\"site\": 725, \"wildtype\": \"P\", \"_stat_site_order\": 722}, {\"site\": 726, \"wildtype\": \"V\", \"_stat_site_order\": 723}, {\"site\": 727, \"wildtype\": \"S\", \"_stat_site_order\": 724}, {\"site\": 728, \"wildtype\": \"M\", \"_stat_site_order\": 725}, {\"site\": 729, \"wildtype\": \"T\", \"_stat_site_order\": 726}, {\"site\": 730, \"wildtype\": \"K\", \"_stat_site_order\": 727}, {\"site\": 731, \"wildtype\": \"T\", \"_stat_site_order\": 728}, {\"site\": 732, \"wildtype\": \"S\", \"_stat_site_order\": 729}, {\"site\": 733, \"wildtype\": \"V\", \"_stat_site_order\": 730}, {\"site\": 734, \"wildtype\": \"D\", \"_stat_site_order\": 731}, {\"site\": 735, \"wildtype\": \"C\", \"_stat_site_order\": 732}, {\"site\": 736, \"wildtype\": \"T\", \"_stat_site_order\": 733}, {\"site\": 737, \"wildtype\": \"M\", \"_stat_site_order\": 734}, {\"site\": 738, \"wildtype\": \"Y\", \"_stat_site_order\": 735}, {\"site\": 739, \"wildtype\": \"I\", \"_stat_site_order\": 736}, {\"site\": 740, \"wildtype\": \"C\", \"_stat_site_order\": 737}, {\"site\": 741, \"wildtype\": \"G\", \"_stat_site_order\": 738}, {\"site\": 742, \"wildtype\": \"D\", \"_stat_site_order\": 739}, {\"site\": 743, \"wildtype\": \"S\", \"_stat_site_order\": 740}, {\"site\": 744, \"wildtype\": \"T\", \"_stat_site_order\": 741}, {\"site\": 745, \"wildtype\": \"E\", \"_stat_site_order\": 742}, {\"site\": 746, \"wildtype\": \"C\", \"_stat_site_order\": 743}, {\"site\": 747, \"wildtype\": \"S\", \"_stat_site_order\": 744}, {\"site\": 748, \"wildtype\": \"N\", \"_stat_site_order\": 745}, {\"site\": 749, \"wildtype\": \"L\", \"_stat_site_order\": 746}, {\"site\": 750, \"wildtype\": \"L\", \"_stat_site_order\": 747}, {\"site\": 751, \"wildtype\": \"L\", \"_stat_site_order\": 748}, {\"site\": 752, \"wildtype\": \"Q\", \"_stat_site_order\": 749}, {\"site\": 753, \"wildtype\": \"Y\", \"_stat_site_order\": 750}, {\"site\": 754, \"wildtype\": \"G\", \"_stat_site_order\": 751}, {\"site\": 755, \"wildtype\": \"S\", \"_stat_site_order\": 752}, {\"site\": 756, \"wildtype\": \"F\", \"_stat_site_order\": 753}, {\"site\": 757, \"wildtype\": \"C\", \"_stat_site_order\": 754}, {\"site\": 758, \"wildtype\": \"T\", \"_stat_site_order\": 755}, {\"site\": 759, \"wildtype\": \"Q\", \"_stat_site_order\": 756}, {\"site\": 760, \"wildtype\": \"L\", \"_stat_site_order\": 757}, {\"site\": 761, \"wildtype\": \"K\", \"_stat_site_order\": 758}, {\"site\": 762, \"wildtype\": \"R\", \"_stat_site_order\": 759}, {\"site\": 763, \"wildtype\": \"A\", \"_stat_site_order\": 760}, {\"site\": 764, \"wildtype\": \"L\", \"_stat_site_order\": 761}, {\"site\": 765, \"wildtype\": \"T\", \"_stat_site_order\": 762}, {\"site\": 766, \"wildtype\": \"G\", \"_stat_site_order\": 763}, {\"site\": 767, \"wildtype\": \"I\", \"_stat_site_order\": 764}, {\"site\": 768, \"wildtype\": \"A\", \"_stat_site_order\": 765}, {\"site\": 769, \"wildtype\": \"V\", \"_stat_site_order\": 766}, {\"site\": 770, \"wildtype\": \"E\", \"_stat_site_order\": 767}, {\"site\": 771, \"wildtype\": \"Q\", \"_stat_site_order\": 768}, {\"site\": 772, \"wildtype\": \"D\", \"_stat_site_order\": 769}, {\"site\": 773, \"wildtype\": \"K\", \"_stat_site_order\": 770}, {\"site\": 774, \"wildtype\": \"N\", \"_stat_site_order\": 771}, {\"site\": 775, \"wildtype\": \"T\", \"_stat_site_order\": 772}, {\"site\": 776, \"wildtype\": \"Q\", \"_stat_site_order\": 773}, {\"site\": 777, \"wildtype\": \"E\", \"_stat_site_order\": 774}, {\"site\": 778, \"wildtype\": \"V\", \"_stat_site_order\": 775}, {\"site\": 779, \"wildtype\": \"F\", \"_stat_site_order\": 776}, {\"site\": 780, \"wildtype\": \"A\", \"_stat_site_order\": 777}, {\"site\": 781, \"wildtype\": \"Q\", \"_stat_site_order\": 778}, {\"site\": 782, \"wildtype\": \"V\", \"_stat_site_order\": 779}, {\"site\": 783, \"wildtype\": \"K\", \"_stat_site_order\": 780}, {\"site\": 784, \"wildtype\": \"Q\", \"_stat_site_order\": 781}, {\"site\": 785, \"wildtype\": \"I\", \"_stat_site_order\": 782}, {\"site\": 786, \"wildtype\": \"Y\", \"_stat_site_order\": 783}, {\"site\": 787, \"wildtype\": \"K\", \"_stat_site_order\": 784}, {\"site\": 788, \"wildtype\": \"T\", \"_stat_site_order\": 785}, {\"site\": 789, \"wildtype\": \"P\", \"_stat_site_order\": 786}, {\"site\": 790, \"wildtype\": \"P\", \"_stat_site_order\": 787}, {\"site\": 791, \"wildtype\": \"I\", \"_stat_site_order\": 788}, {\"site\": 792, \"wildtype\": \"K\", \"_stat_site_order\": 789}, {\"site\": 793, \"wildtype\": \"Y\", \"_stat_site_order\": 790}, {\"site\": 794, \"wildtype\": \"F\", \"_stat_site_order\": 791}, {\"site\": 795, \"wildtype\": \"G\", \"_stat_site_order\": 792}, {\"site\": 796, \"wildtype\": \"G\", \"_stat_site_order\": 793}, {\"site\": 797, \"wildtype\": \"F\", \"_stat_site_order\": 794}, {\"site\": 798, \"wildtype\": \"N\", \"_stat_site_order\": 795}, {\"site\": 799, \"wildtype\": \"F\", \"_stat_site_order\": 796}, {\"site\": 800, \"wildtype\": \"S\", \"_stat_site_order\": 797}, {\"site\": 801, \"wildtype\": \"Q\", \"_stat_site_order\": 798}, {\"site\": 802, \"wildtype\": \"I\", \"_stat_site_order\": 799}, {\"site\": 803, \"wildtype\": \"L\", \"_stat_site_order\": 800}, {\"site\": 804, \"wildtype\": \"P\", \"_stat_site_order\": 801}, {\"site\": 805, \"wildtype\": \"D\", \"_stat_site_order\": 802}, {\"site\": 806, \"wildtype\": \"P\", \"_stat_site_order\": 803}, {\"site\": 807, \"wildtype\": \"S\", \"_stat_site_order\": 804}, {\"site\": 808, \"wildtype\": \"K\", \"_stat_site_order\": 805}, {\"site\": 809, \"wildtype\": \"P\", \"_stat_site_order\": 806}, {\"site\": 810, \"wildtype\": \"S\", \"_stat_site_order\": 807}, {\"site\": 811, \"wildtype\": \"K\", \"_stat_site_order\": 808}, {\"site\": 812, \"wildtype\": \"R\", \"_stat_site_order\": 809}, {\"site\": 813, \"wildtype\": \"S\", \"_stat_site_order\": 810}, {\"site\": 814, \"wildtype\": \"F\", \"_stat_site_order\": 811}, {\"site\": 815, \"wildtype\": \"I\", \"_stat_site_order\": 812}, {\"site\": 816, \"wildtype\": \"E\", \"_stat_site_order\": 813}, {\"site\": 817, \"wildtype\": \"D\", \"_stat_site_order\": 814}, {\"site\": 818, \"wildtype\": \"L\", \"_stat_site_order\": 815}, {\"site\": 819, \"wildtype\": \"L\", \"_stat_site_order\": 816}, {\"site\": 820, \"wildtype\": \"F\", \"_stat_site_order\": 817}, {\"site\": 821, \"wildtype\": \"N\", \"_stat_site_order\": 818}, {\"site\": 822, \"wildtype\": \"K\", \"_stat_site_order\": 819}, {\"site\": 823, \"wildtype\": \"V\", \"_stat_site_order\": 820}, {\"site\": 824, \"wildtype\": \"T\", \"_stat_site_order\": 821}, {\"site\": 825, \"wildtype\": \"L\", \"_stat_site_order\": 822}, {\"site\": 826, \"wildtype\": \"A\", \"_stat_site_order\": 823}, {\"site\": 827, \"wildtype\": \"D\", \"_stat_site_order\": 824}, {\"site\": 828, \"wildtype\": \"A\", \"_stat_site_order\": 825}, {\"site\": 829, \"wildtype\": \"G\", \"_stat_site_order\": 826}, {\"site\": 830, \"wildtype\": \"F\", \"_stat_site_order\": 827}, {\"site\": 831, \"wildtype\": \"I\", \"_stat_site_order\": 828}, {\"site\": 832, \"wildtype\": \"K\", \"_stat_site_order\": 829}, {\"site\": 833, \"wildtype\": \"Q\", \"_stat_site_order\": 830}, {\"site\": 834, \"wildtype\": \"Y\", \"_stat_site_order\": 831}, {\"site\": 835, \"wildtype\": \"G\", \"_stat_site_order\": 832}, {\"site\": 836, \"wildtype\": \"D\", \"_stat_site_order\": 833}, {\"site\": 837, \"wildtype\": \"C\", \"_stat_site_order\": 834}, {\"site\": 838, \"wildtype\": \"L\", \"_stat_site_order\": 835}, {\"site\": 839, \"wildtype\": \"G\", \"_stat_site_order\": 836}, {\"site\": 840, \"wildtype\": \"D\", \"_stat_site_order\": 837}, {\"site\": 841, \"wildtype\": \"I\", \"_stat_site_order\": 838}, {\"site\": 842, \"wildtype\": \"A\", \"_stat_site_order\": 839}, {\"site\": 843, \"wildtype\": \"A\", \"_stat_site_order\": 840}, {\"site\": 844, \"wildtype\": \"R\", \"_stat_site_order\": 841}, {\"site\": 845, \"wildtype\": \"D\", \"_stat_site_order\": 842}, {\"site\": 846, \"wildtype\": \"L\", \"_stat_site_order\": 843}, {\"site\": 847, \"wildtype\": \"I\", \"_stat_site_order\": 844}, {\"site\": 848, \"wildtype\": \"C\", \"_stat_site_order\": 845}, {\"site\": 849, \"wildtype\": \"A\", \"_stat_site_order\": 846}, {\"site\": 850, \"wildtype\": \"Q\", \"_stat_site_order\": 847}, {\"site\": 851, \"wildtype\": \"K\", \"_stat_site_order\": 848}, {\"site\": 852, \"wildtype\": \"F\", \"_stat_site_order\": 849}, {\"site\": 853, \"wildtype\": \"K\", \"_stat_site_order\": 850}, {\"site\": 854, \"wildtype\": \"G\", \"_stat_site_order\": 851}, {\"site\": 855, \"wildtype\": \"L\", \"_stat_site_order\": 852}, {\"site\": 856, \"wildtype\": \"T\", \"_stat_site_order\": 853}, {\"site\": 857, \"wildtype\": \"V\", \"_stat_site_order\": 854}, {\"site\": 858, \"wildtype\": \"L\", \"_stat_site_order\": 855}, {\"site\": 859, \"wildtype\": \"P\", \"_stat_site_order\": 856}, {\"site\": 860, \"wildtype\": \"P\", \"_stat_site_order\": 857}, {\"site\": 861, \"wildtype\": \"L\", \"_stat_site_order\": 858}, {\"site\": 862, \"wildtype\": \"L\", \"_stat_site_order\": 859}, {\"site\": 863, \"wildtype\": \"T\", \"_stat_site_order\": 860}, {\"site\": 864, \"wildtype\": \"D\", \"_stat_site_order\": 861}, {\"site\": 865, \"wildtype\": \"E\", \"_stat_site_order\": 862}, {\"site\": 866, \"wildtype\": \"M\", \"_stat_site_order\": 863}, {\"site\": 867, \"wildtype\": \"I\", \"_stat_site_order\": 864}, {\"site\": 868, \"wildtype\": \"A\", \"_stat_site_order\": 865}, {\"site\": 869, \"wildtype\": \"Q\", \"_stat_site_order\": 866}, {\"site\": 870, \"wildtype\": \"Y\", \"_stat_site_order\": 867}, {\"site\": 871, \"wildtype\": \"T\", \"_stat_site_order\": 868}, {\"site\": 872, \"wildtype\": \"S\", \"_stat_site_order\": 869}, {\"site\": 873, \"wildtype\": \"A\", \"_stat_site_order\": 870}, {\"site\": 874, \"wildtype\": \"L\", \"_stat_site_order\": 871}, {\"site\": 875, \"wildtype\": \"L\", \"_stat_site_order\": 872}, {\"site\": 876, \"wildtype\": \"A\", \"_stat_site_order\": 873}, {\"site\": 877, \"wildtype\": \"G\", \"_stat_site_order\": 874}, {\"site\": 878, \"wildtype\": \"T\", \"_stat_site_order\": 875}, {\"site\": 879, \"wildtype\": \"I\", \"_stat_site_order\": 876}, {\"site\": 880, \"wildtype\": \"T\", \"_stat_site_order\": 877}, {\"site\": 881, \"wildtype\": \"S\", \"_stat_site_order\": 878}, {\"site\": 882, \"wildtype\": \"G\", \"_stat_site_order\": 879}, {\"site\": 883, \"wildtype\": \"W\", \"_stat_site_order\": 880}, {\"site\": 884, \"wildtype\": \"T\", \"_stat_site_order\": 881}, {\"site\": 885, \"wildtype\": \"F\", \"_stat_site_order\": 882}, {\"site\": 886, \"wildtype\": \"G\", \"_stat_site_order\": 883}, {\"site\": 887, \"wildtype\": \"A\", \"_stat_site_order\": 884}, {\"site\": 888, \"wildtype\": \"G\", \"_stat_site_order\": 885}, {\"site\": 889, \"wildtype\": \"A\", \"_stat_site_order\": 886}, {\"site\": 890, \"wildtype\": \"A\", \"_stat_site_order\": 887}, {\"site\": 891, \"wildtype\": \"L\", \"_stat_site_order\": 888}, {\"site\": 892, \"wildtype\": \"Q\", \"_stat_site_order\": 889}, {\"site\": 893, \"wildtype\": \"I\", \"_stat_site_order\": 890}, {\"site\": 894, \"wildtype\": \"P\", \"_stat_site_order\": 891}, {\"site\": 895, \"wildtype\": \"F\", \"_stat_site_order\": 892}, {\"site\": 896, \"wildtype\": \"A\", \"_stat_site_order\": 893}, {\"site\": 897, \"wildtype\": \"M\", \"_stat_site_order\": 894}, {\"site\": 898, \"wildtype\": \"Q\", \"_stat_site_order\": 895}, {\"site\": 899, \"wildtype\": \"M\", \"_stat_site_order\": 896}, {\"site\": 900, \"wildtype\": \"A\", \"_stat_site_order\": 897}, {\"site\": 901, \"wildtype\": \"Y\", \"_stat_site_order\": 898}, {\"site\": 902, \"wildtype\": \"R\", \"_stat_site_order\": 899}, {\"site\": 903, \"wildtype\": \"F\", \"_stat_site_order\": 900}, {\"site\": 904, \"wildtype\": \"N\", \"_stat_site_order\": 901}, {\"site\": 905, \"wildtype\": \"G\", \"_stat_site_order\": 902}, {\"site\": 906, \"wildtype\": \"I\", \"_stat_site_order\": 903}, {\"site\": 907, \"wildtype\": \"G\", \"_stat_site_order\": 904}, {\"site\": 908, \"wildtype\": \"V\", \"_stat_site_order\": 905}, {\"site\": 909, \"wildtype\": \"T\", \"_stat_site_order\": 906}, {\"site\": 910, \"wildtype\": \"Q\", \"_stat_site_order\": 907}, {\"site\": 911, \"wildtype\": \"N\", \"_stat_site_order\": 908}, {\"site\": 912, \"wildtype\": \"V\", \"_stat_site_order\": 909}, {\"site\": 913, \"wildtype\": \"L\", \"_stat_site_order\": 910}, {\"site\": 914, \"wildtype\": \"Y\", \"_stat_site_order\": 911}, {\"site\": 915, \"wildtype\": \"E\", \"_stat_site_order\": 912}, {\"site\": 916, \"wildtype\": \"N\", \"_stat_site_order\": 913}, {\"site\": 917, \"wildtype\": \"Q\", \"_stat_site_order\": 914}, {\"site\": 918, \"wildtype\": \"K\", \"_stat_site_order\": 915}, {\"site\": 919, \"wildtype\": \"L\", \"_stat_site_order\": 916}, {\"site\": 920, \"wildtype\": \"I\", \"_stat_site_order\": 917}, {\"site\": 921, \"wildtype\": \"A\", \"_stat_site_order\": 918}, {\"site\": 922, \"wildtype\": \"N\", \"_stat_site_order\": 919}, {\"site\": 923, \"wildtype\": \"Q\", \"_stat_site_order\": 920}, {\"site\": 924, \"wildtype\": \"F\", \"_stat_site_order\": 921}, {\"site\": 925, \"wildtype\": \"N\", \"_stat_site_order\": 922}, {\"site\": 926, \"wildtype\": \"S\", \"_stat_site_order\": 923}, {\"site\": 927, \"wildtype\": \"A\", \"_stat_site_order\": 924}, {\"site\": 928, \"wildtype\": \"I\", \"_stat_site_order\": 925}, {\"site\": 929, \"wildtype\": \"G\", \"_stat_site_order\": 926}, {\"site\": 930, \"wildtype\": \"K\", \"_stat_site_order\": 927}, {\"site\": 931, \"wildtype\": \"I\", \"_stat_site_order\": 928}, {\"site\": 932, \"wildtype\": \"Q\", \"_stat_site_order\": 929}, {\"site\": 933, \"wildtype\": \"D\", \"_stat_site_order\": 930}, {\"site\": 934, \"wildtype\": \"S\", \"_stat_site_order\": 931}, {\"site\": 935, \"wildtype\": \"L\", \"_stat_site_order\": 932}, {\"site\": 936, \"wildtype\": \"S\", \"_stat_site_order\": 933}, {\"site\": 937, \"wildtype\": \"S\", \"_stat_site_order\": 934}, {\"site\": 938, \"wildtype\": \"T\", \"_stat_site_order\": 935}, {\"site\": 939, \"wildtype\": \"A\", \"_stat_site_order\": 936}, {\"site\": 940, \"wildtype\": \"S\", \"_stat_site_order\": 937}, {\"site\": 941, \"wildtype\": \"A\", \"_stat_site_order\": 938}, {\"site\": 942, \"wildtype\": \"L\", \"_stat_site_order\": 939}, {\"site\": 943, \"wildtype\": \"G\", \"_stat_site_order\": 940}, {\"site\": 944, \"wildtype\": \"K\", \"_stat_site_order\": 941}, {\"site\": 945, \"wildtype\": \"L\", \"_stat_site_order\": 942}, {\"site\": 946, \"wildtype\": \"Q\", \"_stat_site_order\": 943}, {\"site\": 947, \"wildtype\": \"D\", \"_stat_site_order\": 944}, {\"site\": 948, \"wildtype\": \"V\", \"_stat_site_order\": 945}, {\"site\": 949, \"wildtype\": \"V\", \"_stat_site_order\": 946}, {\"site\": 950, \"wildtype\": \"N\", \"_stat_site_order\": 947}, {\"site\": 951, \"wildtype\": \"H\", \"_stat_site_order\": 948}, {\"site\": 952, \"wildtype\": \"N\", \"_stat_site_order\": 949}, {\"site\": 953, \"wildtype\": \"A\", \"_stat_site_order\": 950}, {\"site\": 954, \"wildtype\": \"Q\", \"_stat_site_order\": 951}, {\"site\": 955, \"wildtype\": \"A\", \"_stat_site_order\": 952}, {\"site\": 956, \"wildtype\": \"L\", \"_stat_site_order\": 953}, {\"site\": 957, \"wildtype\": \"N\", \"_stat_site_order\": 954}, {\"site\": 958, \"wildtype\": \"T\", \"_stat_site_order\": 955}, {\"site\": 959, \"wildtype\": \"L\", \"_stat_site_order\": 956}, {\"site\": 960, \"wildtype\": \"V\", \"_stat_site_order\": 957}, {\"site\": 961, \"wildtype\": \"K\", \"_stat_site_order\": 958}, {\"site\": 962, \"wildtype\": \"Q\", \"_stat_site_order\": 959}, {\"site\": 963, \"wildtype\": \"L\", \"_stat_site_order\": 960}, {\"site\": 964, \"wildtype\": \"S\", \"_stat_site_order\": 961}, {\"site\": 965, \"wildtype\": \"S\", \"_stat_site_order\": 962}, {\"site\": 966, \"wildtype\": \"K\", \"_stat_site_order\": 963}, {\"site\": 967, \"wildtype\": \"F\", \"_stat_site_order\": 964}, {\"site\": 968, \"wildtype\": \"G\", \"_stat_site_order\": 965}, {\"site\": 969, \"wildtype\": \"A\", \"_stat_site_order\": 966}, {\"site\": 970, \"wildtype\": \"I\", \"_stat_site_order\": 967}, {\"site\": 971, \"wildtype\": \"S\", \"_stat_site_order\": 968}, {\"site\": 972, \"wildtype\": \"S\", \"_stat_site_order\": 969}, {\"site\": 973, \"wildtype\": \"V\", \"_stat_site_order\": 970}, {\"site\": 974, \"wildtype\": \"L\", \"_stat_site_order\": 971}, {\"site\": 975, \"wildtype\": \"N\", \"_stat_site_order\": 972}, {\"site\": 976, \"wildtype\": \"D\", \"_stat_site_order\": 973}, {\"site\": 977, \"wildtype\": \"I\", \"_stat_site_order\": 974}, {\"site\": 978, \"wildtype\": \"F\", \"_stat_site_order\": 975}, {\"site\": 979, \"wildtype\": \"S\", \"_stat_site_order\": 976}, {\"site\": 980, \"wildtype\": \"R\", \"_stat_site_order\": 977}, {\"site\": 981, \"wildtype\": \"L\", \"_stat_site_order\": 978}, {\"site\": 982, \"wildtype\": \"D\", \"_stat_site_order\": 979}, {\"site\": 983, \"wildtype\": \"K\", \"_stat_site_order\": 980}, {\"site\": 984, \"wildtype\": \"V\", \"_stat_site_order\": 981}, {\"site\": 985, \"wildtype\": \"E\", \"_stat_site_order\": 982}, {\"site\": 986, \"wildtype\": \"A\", \"_stat_site_order\": 983}, {\"site\": 987, \"wildtype\": \"E\", \"_stat_site_order\": 984}, {\"site\": 988, \"wildtype\": \"V\", \"_stat_site_order\": 985}, {\"site\": 989, \"wildtype\": \"Q\", \"_stat_site_order\": 986}, {\"site\": 990, \"wildtype\": \"I\", \"_stat_site_order\": 987}, {\"site\": 991, \"wildtype\": \"D\", \"_stat_site_order\": 988}, {\"site\": 992, \"wildtype\": \"R\", \"_stat_site_order\": 989}, {\"site\": 993, \"wildtype\": \"L\", \"_stat_site_order\": 990}, {\"site\": 994, \"wildtype\": \"I\", \"_stat_site_order\": 991}, {\"site\": 995, \"wildtype\": \"T\", \"_stat_site_order\": 992}, {\"site\": 996, \"wildtype\": \"G\", \"_stat_site_order\": 993}, {\"site\": 997, \"wildtype\": \"R\", \"_stat_site_order\": 994}, {\"site\": 998, \"wildtype\": \"L\", \"_stat_site_order\": 995}, {\"site\": 999, \"wildtype\": \"Q\", \"_stat_site_order\": 996}, {\"site\": 1000, \"wildtype\": \"S\", \"_stat_site_order\": 997}, {\"site\": 1001, \"wildtype\": \"L\", \"_stat_site_order\": 998}, {\"site\": 1002, \"wildtype\": \"Q\", \"_stat_site_order\": 999}, {\"site\": 1003, \"wildtype\": \"T\", \"_stat_site_order\": 1000}, {\"site\": 1004, \"wildtype\": \"Y\", \"_stat_site_order\": 1001}, {\"site\": 1005, \"wildtype\": \"V\", \"_stat_site_order\": 1002}, {\"site\": 1006, \"wildtype\": \"T\", \"_stat_site_order\": 1003}, {\"site\": 1007, \"wildtype\": \"Q\", \"_stat_site_order\": 1004}, {\"site\": 1008, \"wildtype\": \"Q\", \"_stat_site_order\": 1005}, {\"site\": 1009, \"wildtype\": \"L\", \"_stat_site_order\": 1006}, {\"site\": 1010, \"wildtype\": \"I\", \"_stat_site_order\": 1007}, {\"site\": 1011, \"wildtype\": \"R\", \"_stat_site_order\": 1008}, {\"site\": 1012, \"wildtype\": \"A\", \"_stat_site_order\": 1009}, {\"site\": 1013, \"wildtype\": \"A\", \"_stat_site_order\": 1010}, {\"site\": 1014, \"wildtype\": \"E\", \"_stat_site_order\": 1011}, {\"site\": 1015, \"wildtype\": \"I\", \"_stat_site_order\": 1012}, {\"site\": 1016, \"wildtype\": \"R\", \"_stat_site_order\": 1013}, {\"site\": 1017, \"wildtype\": \"A\", \"_stat_site_order\": 1014}, {\"site\": 1018, \"wildtype\": \"S\", \"_stat_site_order\": 1015}, {\"site\": 1019, \"wildtype\": \"A\", \"_stat_site_order\": 1016}, {\"site\": 1020, \"wildtype\": \"N\", \"_stat_site_order\": 1017}, {\"site\": 1021, \"wildtype\": \"L\", \"_stat_site_order\": 1018}, {\"site\": 1022, \"wildtype\": \"A\", \"_stat_site_order\": 1019}, {\"site\": 1023, \"wildtype\": \"A\", \"_stat_site_order\": 1020}, {\"site\": 1024, \"wildtype\": \"T\", \"_stat_site_order\": 1021}, {\"site\": 1025, \"wildtype\": \"K\", \"_stat_site_order\": 1022}, {\"site\": 1026, \"wildtype\": \"M\", \"_stat_site_order\": 1023}, {\"site\": 1027, \"wildtype\": \"S\", \"_stat_site_order\": 1024}, {\"site\": 1028, \"wildtype\": \"E\", \"_stat_site_order\": 1025}, {\"site\": 1029, \"wildtype\": \"C\", \"_stat_site_order\": 1026}, {\"site\": 1030, \"wildtype\": \"V\", \"_stat_site_order\": 1027}, {\"site\": 1031, \"wildtype\": \"L\", \"_stat_site_order\": 1028}, {\"site\": 1032, \"wildtype\": \"G\", \"_stat_site_order\": 1029}, {\"site\": 1033, \"wildtype\": \"Q\", \"_stat_site_order\": 1030}, {\"site\": 1034, \"wildtype\": \"S\", \"_stat_site_order\": 1031}, {\"site\": 1035, \"wildtype\": \"K\", \"_stat_site_order\": 1032}, {\"site\": 1036, \"wildtype\": \"R\", \"_stat_site_order\": 1033}, {\"site\": 1037, \"wildtype\": \"V\", \"_stat_site_order\": 1034}, {\"site\": 1038, \"wildtype\": \"D\", \"_stat_site_order\": 1035}, {\"site\": 1039, \"wildtype\": \"F\", \"_stat_site_order\": 1036}, {\"site\": 1040, \"wildtype\": \"C\", \"_stat_site_order\": 1037}, {\"site\": 1041, \"wildtype\": \"G\", \"_stat_site_order\": 1038}, {\"site\": 1042, \"wildtype\": \"K\", \"_stat_site_order\": 1039}, {\"site\": 1043, \"wildtype\": \"G\", \"_stat_site_order\": 1040}, {\"site\": 1044, \"wildtype\": \"Y\", \"_stat_site_order\": 1041}, {\"site\": 1045, \"wildtype\": \"H\", \"_stat_site_order\": 1042}, {\"site\": 1046, \"wildtype\": \"L\", \"_stat_site_order\": 1043}, {\"site\": 1047, \"wildtype\": \"M\", \"_stat_site_order\": 1044}, {\"site\": 1048, \"wildtype\": \"S\", \"_stat_site_order\": 1045}, {\"site\": 1049, \"wildtype\": \"F\", \"_stat_site_order\": 1046}, {\"site\": 1051, \"wildtype\": \"Q\", \"_stat_site_order\": 1047}, {\"site\": 1052, \"wildtype\": \"S\", \"_stat_site_order\": 1048}, {\"site\": 1053, \"wildtype\": \"A\", \"_stat_site_order\": 1049}, {\"site\": 1054, \"wildtype\": \"P\", \"_stat_site_order\": 1050}, {\"site\": 1055, \"wildtype\": \"H\", \"_stat_site_order\": 1051}, {\"site\": 1056, \"wildtype\": \"G\", \"_stat_site_order\": 1052}, {\"site\": 1057, \"wildtype\": \"V\", \"_stat_site_order\": 1053}, {\"site\": 1058, \"wildtype\": \"V\", \"_stat_site_order\": 1054}, {\"site\": 1059, \"wildtype\": \"F\", \"_stat_site_order\": 1055}, {\"site\": 1060, \"wildtype\": \"L\", \"_stat_site_order\": 1056}, {\"site\": 1061, \"wildtype\": \"H\", \"_stat_site_order\": 1057}, {\"site\": 1062, \"wildtype\": \"V\", \"_stat_site_order\": 1058}, {\"site\": 1063, \"wildtype\": \"T\", \"_stat_site_order\": 1059}, {\"site\": 1064, \"wildtype\": \"Y\", \"_stat_site_order\": 1060}, {\"site\": 1065, \"wildtype\": \"V\", \"_stat_site_order\": 1061}, {\"site\": 1066, \"wildtype\": \"P\", \"_stat_site_order\": 1062}, {\"site\": 1067, \"wildtype\": \"A\", \"_stat_site_order\": 1063}, {\"site\": 1068, \"wildtype\": \"Q\", \"_stat_site_order\": 1064}, {\"site\": 1069, \"wildtype\": \"E\", \"_stat_site_order\": 1065}, {\"site\": 1070, \"wildtype\": \"K\", \"_stat_site_order\": 1066}, {\"site\": 1071, \"wildtype\": \"N\", \"_stat_site_order\": 1067}, {\"site\": 1072, \"wildtype\": \"F\", \"_stat_site_order\": 1068}, {\"site\": 1073, \"wildtype\": \"T\", \"_stat_site_order\": 1069}, {\"site\": 1074, \"wildtype\": \"T\", \"_stat_site_order\": 1070}, {\"site\": 1075, \"wildtype\": \"A\", \"_stat_site_order\": 1071}, {\"site\": 1076, \"wildtype\": \"P\", \"_stat_site_order\": 1072}, {\"site\": 1077, \"wildtype\": \"A\", \"_stat_site_order\": 1073}, {\"site\": 1078, \"wildtype\": \"I\", \"_stat_site_order\": 1074}, {\"site\": 1079, \"wildtype\": \"C\", \"_stat_site_order\": 1075}, {\"site\": 1080, \"wildtype\": \"H\", \"_stat_site_order\": 1076}, {\"site\": 1081, \"wildtype\": \"D\", \"_stat_site_order\": 1077}, {\"site\": 1082, \"wildtype\": \"G\", \"_stat_site_order\": 1078}, {\"site\": 1083, \"wildtype\": \"K\", \"_stat_site_order\": 1079}, {\"site\": 1084, \"wildtype\": \"A\", \"_stat_site_order\": 1080}, {\"site\": 1085, \"wildtype\": \"H\", \"_stat_site_order\": 1081}, {\"site\": 1086, \"wildtype\": \"F\", \"_stat_site_order\": 1082}, {\"site\": 1087, \"wildtype\": \"P\", \"_stat_site_order\": 1083}, {\"site\": 1088, \"wildtype\": \"R\", \"_stat_site_order\": 1084}, {\"site\": 1089, \"wildtype\": \"E\", \"_stat_site_order\": 1085}, {\"site\": 1090, \"wildtype\": \"G\", \"_stat_site_order\": 1086}, {\"site\": 1091, \"wildtype\": \"V\", \"_stat_site_order\": 1087}, {\"site\": 1092, \"wildtype\": \"F\", \"_stat_site_order\": 1088}, {\"site\": 1093, \"wildtype\": \"V\", \"_stat_site_order\": 1089}, {\"site\": 1094, \"wildtype\": \"S\", \"_stat_site_order\": 1090}, {\"site\": 1095, \"wildtype\": \"N\", \"_stat_site_order\": 1091}, {\"site\": 1096, \"wildtype\": \"G\", \"_stat_site_order\": 1092}, {\"site\": 1097, \"wildtype\": \"T\", \"_stat_site_order\": 1093}, {\"site\": 1098, \"wildtype\": \"H\", \"_stat_site_order\": 1094}, {\"site\": 1099, \"wildtype\": \"W\", \"_stat_site_order\": 1095}, {\"site\": 1100, \"wildtype\": \"F\", \"_stat_site_order\": 1096}, {\"site\": 1101, \"wildtype\": \"V\", \"_stat_site_order\": 1097}, {\"site\": 1102, \"wildtype\": \"T\", \"_stat_site_order\": 1098}, {\"site\": 1103, \"wildtype\": \"Q\", \"_stat_site_order\": 1099}, {\"site\": 1104, \"wildtype\": \"R\", \"_stat_site_order\": 1100}, {\"site\": 1105, \"wildtype\": \"N\", \"_stat_site_order\": 1101}, {\"site\": 1106, \"wildtype\": \"F\", \"_stat_site_order\": 1102}, {\"site\": 1107, \"wildtype\": \"Y\", \"_stat_site_order\": 1103}, {\"site\": 1108, \"wildtype\": \"E\", \"_stat_site_order\": 1104}, {\"site\": 1109, \"wildtype\": \"P\", \"_stat_site_order\": 1105}, {\"site\": 1110, \"wildtype\": \"Q\", \"_stat_site_order\": 1106}, {\"site\": 1111, \"wildtype\": \"I\", \"_stat_site_order\": 1107}, {\"site\": 1112, \"wildtype\": \"I\", \"_stat_site_order\": 1108}, {\"site\": 1113, \"wildtype\": \"T\", \"_stat_site_order\": 1109}, {\"site\": 1114, \"wildtype\": \"T\", \"_stat_site_order\": 1110}, {\"site\": 1115, \"wildtype\": \"D\", \"_stat_site_order\": 1111}, {\"site\": 1116, \"wildtype\": \"N\", \"_stat_site_order\": 1112}, {\"site\": 1117, \"wildtype\": \"T\", \"_stat_site_order\": 1113}, {\"site\": 1118, \"wildtype\": \"F\", \"_stat_site_order\": 1114}, {\"site\": 1119, \"wildtype\": \"V\", \"_stat_site_order\": 1115}, {\"site\": 1120, \"wildtype\": \"S\", \"_stat_site_order\": 1116}, {\"site\": 1121, \"wildtype\": \"G\", \"_stat_site_order\": 1117}, {\"site\": 1122, \"wildtype\": \"N\", \"_stat_site_order\": 1118}, {\"site\": 1123, \"wildtype\": \"C\", \"_stat_site_order\": 1119}, {\"site\": 1124, \"wildtype\": \"D\", \"_stat_site_order\": 1120}, {\"site\": 1125, \"wildtype\": \"V\", \"_stat_site_order\": 1121}, {\"site\": 1126, \"wildtype\": \"V\", \"_stat_site_order\": 1122}, {\"site\": 1127, \"wildtype\": \"I\", \"_stat_site_order\": 1123}, {\"site\": 1128, \"wildtype\": \"G\", \"_stat_site_order\": 1124}, {\"site\": 1129, \"wildtype\": \"I\", \"_stat_site_order\": 1125}, {\"site\": 1130, \"wildtype\": \"V\", \"_stat_site_order\": 1126}, {\"site\": 1131, \"wildtype\": \"N\", \"_stat_site_order\": 1127}, {\"site\": 1132, \"wildtype\": \"N\", \"_stat_site_order\": 1128}, {\"site\": 1133, \"wildtype\": \"T\", \"_stat_site_order\": 1129}, {\"site\": 1134, \"wildtype\": \"V\", \"_stat_site_order\": 1130}, {\"site\": 1135, \"wildtype\": \"Y\", \"_stat_site_order\": 1131}, {\"site\": 1136, \"wildtype\": \"D\", \"_stat_site_order\": 1132}, {\"site\": 1137, \"wildtype\": \"P\", \"_stat_site_order\": 1133}, {\"site\": 1138, \"wildtype\": \"L\", \"_stat_site_order\": 1134}, {\"site\": 1139, \"wildtype\": \"Q\", \"_stat_site_order\": 1135}, {\"site\": 1140, \"wildtype\": \"P\", \"_stat_site_order\": 1136}, {\"site\": 1141, \"wildtype\": \"E\", \"_stat_site_order\": 1137}, {\"site\": 1142, \"wildtype\": \"L\", \"_stat_site_order\": 1138}, {\"site\": 1143, \"wildtype\": \"D\", \"_stat_site_order\": 1139}, {\"site\": 1144, \"wildtype\": \"S\", \"_stat_site_order\": 1140}, {\"site\": 1145, \"wildtype\": \"F\", \"_stat_site_order\": 1141}, {\"site\": 1146, \"wildtype\": \"K\", \"_stat_site_order\": 1142}, {\"site\": 1147, \"wildtype\": \"E\", \"_stat_site_order\": 1143}, {\"site\": 1148, \"wildtype\": \"E\", \"_stat_site_order\": 1144}, {\"site\": 1149, \"wildtype\": \"L\", \"_stat_site_order\": 1145}, {\"site\": 1150, \"wildtype\": \"D\", \"_stat_site_order\": 1146}, {\"site\": 1151, \"wildtype\": \"K\", \"_stat_site_order\": 1147}, {\"site\": 1152, \"wildtype\": \"Y\", \"_stat_site_order\": 1148}, {\"site\": 1153, \"wildtype\": \"F\", \"_stat_site_order\": 1149}, {\"site\": 1154, \"wildtype\": \"K\", \"_stat_site_order\": 1150}, {\"site\": 1155, \"wildtype\": \"N\", \"_stat_site_order\": 1151}, {\"site\": 1156, \"wildtype\": \"H\", \"_stat_site_order\": 1152}, {\"site\": 1157, \"wildtype\": \"T\", \"_stat_site_order\": 1153}, {\"site\": 1158, \"wildtype\": \"S\", \"_stat_site_order\": 1154}, {\"site\": 1159, \"wildtype\": \"P\", \"_stat_site_order\": 1155}, {\"site\": 1160, \"wildtype\": \"D\", \"_stat_site_order\": 1156}, {\"site\": 1161, \"wildtype\": \"V\", \"_stat_site_order\": 1157}, {\"site\": 1162, \"wildtype\": \"D\", \"_stat_site_order\": 1158}, {\"site\": 1163, \"wildtype\": \"L\", \"_stat_site_order\": 1159}, {\"site\": 1164, \"wildtype\": \"G\", \"_stat_site_order\": 1160}, {\"site\": 1165, \"wildtype\": \"D\", \"_stat_site_order\": 1161}, {\"site\": 1166, \"wildtype\": \"I\", \"_stat_site_order\": 1162}, {\"site\": 1167, \"wildtype\": \"S\", \"_stat_site_order\": 1163}, {\"site\": 1168, \"wildtype\": \"G\", \"_stat_site_order\": 1164}, {\"site\": 1169, \"wildtype\": \"I\", \"_stat_site_order\": 1165}, {\"site\": 1170, \"wildtype\": \"N\", \"_stat_site_order\": 1166}, {\"site\": 1171, \"wildtype\": \"A\", \"_stat_site_order\": 1167}, {\"site\": 1172, \"wildtype\": \"S\", \"_stat_site_order\": 1168}, {\"site\": 1173, \"wildtype\": \"V\", \"_stat_site_order\": 1169}, {\"site\": 1174, \"wildtype\": \"V\", \"_stat_site_order\": 1170}, {\"site\": 1175, \"wildtype\": \"N\", \"_stat_site_order\": 1171}, {\"site\": 1176, \"wildtype\": \"I\", \"_stat_site_order\": 1172}, {\"site\": 1177, \"wildtype\": \"Q\", \"_stat_site_order\": 1173}, {\"site\": 1178, \"wildtype\": \"K\", \"_stat_site_order\": 1174}, {\"site\": 1179, \"wildtype\": \"E\", \"_stat_site_order\": 1175}, {\"site\": 1180, \"wildtype\": \"I\", \"_stat_site_order\": 1176}, {\"site\": 1181, \"wildtype\": \"D\", \"_stat_site_order\": 1177}, {\"site\": 1182, \"wildtype\": \"R\", \"_stat_site_order\": 1178}, {\"site\": 1183, \"wildtype\": \"L\", \"_stat_site_order\": 1179}, {\"site\": 1184, \"wildtype\": \"N\", \"_stat_site_order\": 1180}, {\"site\": 1185, \"wildtype\": \"E\", \"_stat_site_order\": 1181}, {\"site\": 1186, \"wildtype\": \"V\", \"_stat_site_order\": 1182}, {\"site\": 1187, \"wildtype\": \"A\", \"_stat_site_order\": 1183}, {\"site\": 1188, \"wildtype\": \"K\", \"_stat_site_order\": 1184}, {\"site\": 1189, \"wildtype\": \"N\", \"_stat_site_order\": 1185}, {\"site\": 1190, \"wildtype\": \"L\", \"_stat_site_order\": 1186}, {\"site\": 1191, \"wildtype\": \"N\", \"_stat_site_order\": 1187}, {\"site\": 1192, \"wildtype\": \"E\", \"_stat_site_order\": 1188}, {\"site\": 1193, \"wildtype\": \"S\", \"_stat_site_order\": 1189}, {\"site\": 1194, \"wildtype\": \"L\", \"_stat_site_order\": 1190}, {\"site\": 1195, \"wildtype\": \"I\", \"_stat_site_order\": 1191}, {\"site\": 1196, \"wildtype\": \"D\", \"_stat_site_order\": 1192}, {\"site\": 1197, \"wildtype\": \"L\", \"_stat_site_order\": 1193}, {\"site\": 1198, \"wildtype\": \"Q\", \"_stat_site_order\": 1194}, {\"site\": 1199, \"wildtype\": \"E\", \"_stat_site_order\": 1195}, {\"site\": 1200, \"wildtype\": \"L\", \"_stat_site_order\": 1196}, {\"site\": 1201, \"wildtype\": \"G\", \"_stat_site_order\": 1197}, {\"site\": 1202, \"wildtype\": \"K\", \"_stat_site_order\": 1198}, {\"site\": 1203, \"wildtype\": \"Y\", \"_stat_site_order\": 1199}, {\"site\": 1204, \"wildtype\": \"E\", \"_stat_site_order\": 1200}, {\"site\": 1205, \"wildtype\": \"Q\", \"_stat_site_order\": 1201}, {\"site\": 1206, \"wildtype\": \"Y\", \"_stat_site_order\": 1202}, {\"site\": 1207, \"wildtype\": \"I\", \"_stat_site_order\": 1203}, {\"site\": 1208, \"wildtype\": \"K\", \"_stat_site_order\": 1204}, {\"site\": 1209, \"wildtype\": \"W\", \"_stat_site_order\": 1205}, {\"site\": 1210, \"wildtype\": \"P\", \"_stat_site_order\": 1206}, {\"site\": 1211, \"wildtype\": \"W\", \"_stat_site_order\": 1207}, {\"site\": 1212, \"wildtype\": \"Y\", \"_stat_site_order\": 1208}, {\"site\": 1213, \"wildtype\": \"I\", \"_stat_site_order\": 1209}, {\"site\": 1214, \"wildtype\": \"W\", \"_stat_site_order\": 1210}, {\"site\": 1215, \"wildtype\": \"L\", \"_stat_site_order\": 1211}, {\"site\": 1216, \"wildtype\": \"G\", \"_stat_site_order\": 1212}, {\"site\": 1217, \"wildtype\": \"F\", \"_stat_site_order\": 1213}, {\"site\": 1218, \"wildtype\": \"I\", \"_stat_site_order\": 1214}, {\"site\": 1219, \"wildtype\": \"A\", \"_stat_site_order\": 1215}, {\"site\": 1220, \"wildtype\": \"G\", \"_stat_site_order\": 1216}, {\"site\": 1221, \"wildtype\": \"L\", \"_stat_site_order\": 1217}, {\"site\": 1222, \"wildtype\": \"I\", \"_stat_site_order\": 1218}, {\"site\": 1223, \"wildtype\": \"A\", \"_stat_site_order\": 1219}, {\"site\": 1224, \"wildtype\": \"I\", \"_stat_site_order\": 1220}, {\"site\": 1225, \"wildtype\": \"V\", \"_stat_site_order\": 1221}, {\"site\": 1226, \"wildtype\": \"M\", \"_stat_site_order\": 1222}, {\"site\": 1227, \"wildtype\": \"V\", \"_stat_site_order\": 1223}, {\"site\": 1228, \"wildtype\": \"T\", \"_stat_site_order\": 1224}, {\"site\": 1229, \"wildtype\": \"I\", \"_stat_site_order\": 1225}, {\"site\": 1230, \"wildtype\": \"M\", \"_stat_site_order\": 1226}, {\"site\": 1231, \"wildtype\": \"L\", \"_stat_site_order\": 1227}, {\"site\": 1232, \"wildtype\": \"C\", \"_stat_site_order\": 1228}, {\"site\": 1233, \"wildtype\": \"C\", \"_stat_site_order\": 1229}, {\"site\": 1234, \"wildtype\": \"M\", \"_stat_site_order\": 1230}, {\"site\": 1235, \"wildtype\": \"T\", \"_stat_site_order\": 1231}, {\"site\": 1236, \"wildtype\": \"S\", \"_stat_site_order\": 1232}, {\"site\": 1237, \"wildtype\": \"C\", \"_stat_site_order\": 1233}, {\"site\": 1238, \"wildtype\": \"C\", \"_stat_site_order\": 1234}, {\"site\": 1239, \"wildtype\": \"S\", \"_stat_site_order\": 1235}, {\"site\": 1240, \"wildtype\": \"C\", \"_stat_site_order\": 1236}, {\"site\": 1241, \"wildtype\": \"L\", \"_stat_site_order\": 1237}, {\"site\": 1242, \"wildtype\": \"K\", \"_stat_site_order\": 1238}, {\"site\": 1243, \"wildtype\": \"G\", \"_stat_site_order\": 1239}, {\"site\": 1244, \"wildtype\": \"C\", \"_stat_site_order\": 1240}, {\"site\": 1245, \"wildtype\": \"C\", \"_stat_site_order\": 1241}, {\"site\": 1246, \"wildtype\": \"S\", \"_stat_site_order\": 1242}, {\"site\": 1247, \"wildtype\": \"C\", \"_stat_site_order\": 1243}, {\"site\": 1248, \"wildtype\": \"G\", \"_stat_site_order\": 1244}, {\"site\": 1249, \"wildtype\": \"S\", \"_stat_site_order\": 1245}, {\"site\": 1250, \"wildtype\": \"*\", \"_stat_site_order\": 1246}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
        "alt.VConcatChart(...)"
       ]
      },
-     "execution_count": 16,
+     "execution_count": 10,
      "metadata": {},
      "output_type": "execute_result"
     }
@@ -1052,13 +982,6 @@
    "execution_count": 11,
    "id": "837eb0ea-e56e-4b5a-badd-94923ceca75d",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:36:02.142398Z",
-     "iopub.status.busy": "2023-08-18T19:36:02.142129Z",
-     "iopub.status.idle": "2023-08-18T19:36:03.130230Z",
-     "shell.execute_reply": "2023-08-18T19:36:03.129154Z",
-     "shell.execute_reply.started": "2023-08-18T19:36:02.142384Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -1067,28 +990,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-3350762f22224997875b9679a679746f.vega-embed {\n",
+       "  #altair-viz-f355df1b852e495abc5e239b1a54635c.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-3350762f22224997875b9679a679746f.vega-embed details,\n",
-       "  #altair-viz-3350762f22224997875b9679a679746f.vega-embed details summary {\n",
+       "  #altair-viz-f355df1b852e495abc5e239b1a54635c.vega-embed details,\n",
+       "  #altair-viz-f355df1b852e495abc5e239b1a54635c.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-3350762f22224997875b9679a679746f\"></div>\n",
+       "<div id=\"altair-viz-f355df1b852e495abc5e239b1a54635c\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-3350762f22224997875b9679a679746f\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-3350762f22224997875b9679a679746f\");\n",
+       "    if (outputDiv.id !== \"altair-viz-f355df1b852e495abc5e239b1a54635c\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-f355df1b852e495abc5e239b1a54635c\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -1124,12 +1047,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_8\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_7\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_12['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_13['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_14\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_12['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_13['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-f7428ceda7487baef303d8bfabdab611\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_9\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_12['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_13['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_12['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_13['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 6.9968035172164935, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_12['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_13['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_12['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_13['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-f7428ceda7487baef303d8bfabdab611\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_15\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_8\", \"view_7\", \"view_9\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_7\"]}, {\"name\": \"param_14\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_7\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -1.2399737883008233], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_8\", \"view_7\", \"view_9\"]}, {\"name\": \"param_11\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 0.8558, \"min\": -3.2612, \"name\": \"minimum functional effect\"}, \"value\": [{\"cutoff\": -3.3409}], \"views\": [\"view_8\", \"view_7\", \"view_9\"]}, {\"name\": \"param_12\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": [{\"cutoff\": 1}], \"views\": [\"view_8\", \"view_7\", \"view_9\"]}, {\"name\": \"param_13\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 6.9968035172164935, \"min\": -1.2399737883008233, \"name\": \"minimum max of escape at site\"}, \"value\": [{\"cutoff\": -1.2399737883008233}], \"views\": [\"view_8\", \"view_7\", \"view_9\"]}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-4a34a2ae7098d9d68cc4385b731fce96\": [{\"site\": 434, \"_stat_site_order\": 0}, {\"site\": 435, \"_stat_site_order\": 1}, {\"site\": 436, \"_stat_site_order\": 2}, {\"site\": 437, \"_stat_site_order\": 3}, {\"site\": 438, \"_stat_site_order\": 4}, {\"site\": 439, \"_stat_site_order\": 5}, {\"site\": 440, \"_stat_site_order\": 6}, {\"site\": 441, \"_stat_site_order\": 7}, {\"site\": 442, \"_stat_site_order\": 8}, {\"site\": 443, \"_stat_site_order\": 9}, {\"site\": 444, \"_stat_site_order\": 10}, {\"site\": 445, \"_stat_site_order\": 11}, {\"site\": 446, \"_stat_site_order\": 12}, {\"site\": 447, \"_stat_site_order\": 13}, {\"site\": 448, \"_stat_site_order\": 14}, {\"site\": 449, \"_stat_site_order\": 15}, {\"site\": 450, \"_stat_site_order\": 16}, {\"site\": 451, \"_stat_site_order\": 17}], \"data-f7428ceda7487baef303d8bfabdab611\": [{\"site\": 434, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": -0.003605423094993517, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": 0.049654989423796196, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.3883, \"times_seen\": 5.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 1.9593342122028008, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.1849, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.013130374483286905, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.9279, \"times_seen\": 2.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.02367571737523028, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.7564, \"times_seen\": 1.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 2.9902588777693517, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.0882, \"times_seen\": 8.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 0.05101136631475868, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.1017, \"times_seen\": 6.0}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"-\", \"escape\": 1.5385704621224816, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.4674, \"times_seen\": 1.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": 0.016876975686188816, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.027074082227422067, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": 3.839339491084656, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.0061703486041247, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.03499239047798595, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.007452001126785125, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 2.6638838987662563, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": 0.04943721062257711, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.001175724486255462, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": 0.019514357374329702, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": 0.02288760395355997, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 3.842039706589607, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 4.280575467950762, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": 0.005026561001255139, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"W\", \"escape\": 0.01704523720368397, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 4.840163734877134, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"A\", \"escape\": -0.016187379040567468, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.028, \"times_seen\": 21.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"C\", \"escape\": 0.0020952787629950724, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.979, \"times_seen\": 1.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"D\", \"escape\": 2.0714394191790726, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1224, \"times_seen\": 14.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": -0.02458861343075173, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.3113, \"times_seen\": 15.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"F\", \"escape\": 2.077082419506872, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.206, \"times_seen\": 5.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"G\", \"escape\": -0.025010990291817654, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0017, \"times_seen\": 24.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"H\", \"escape\": 0.44523630283579185, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.221, \"times_seen\": 12.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": -0.011955039118754979, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8004, \"times_seen\": 13.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": 0.06674394656277079, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8499, \"times_seen\": 18.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 0.021504323662662934, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.0401, \"times_seen\": 10.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": -0.04449714367212812, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2118, \"times_seen\": 36.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"P\", \"escape\": 0.03700577442486714, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.534, \"times_seen\": 8.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"Q\", \"escape\": 0.009798291681692326, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1906, \"times_seen\": 16.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": -0.07259669208489553, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.1206, \"times_seen\": 36.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"S\", \"escape\": 0.03806882712281091, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2856, \"times_seen\": 44.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": -0.041700776104086686, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0087, \"times_seen\": 29.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"V\", \"escape\": 1.5346382462439476, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.4789, \"times_seen\": 13.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"W\", \"escape\": 0.006918148207380637, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.2464, \"times_seen\": 5.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"Y\", \"escape\": 0.026959119161880228, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.2806, \"times_seen\": 16.0}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"*\", \"escape\": -0.42527813861704267, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.7496, \"times_seen\": 5.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.025887618917153174, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.1303, \"times_seen\": 10.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.0010546119797628876, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0594, \"times_seen\": 19.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": -0.006023654749645401, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0273, \"times_seen\": 3.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": -0.027509800937071022, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -2.2021, \"times_seen\": 6.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": -0.006392539814038205, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.4385, \"times_seen\": 1.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": -0.009859570194722896, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.74, \"times_seen\": 7.0}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.002384512751299189, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.3662, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"E\", \"escape\": 0.036966492849980485, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.6793, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"N\", \"escape\": -0.007388632704244411, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -2.4152, \"times_seen\": 1.0}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"V\", \"escape\": 0.017239849869309973, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -0.8693, \"times_seen\": 2.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.0014282848810145583, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.02547035101203864, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 1.4854199203475613, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.029425100714127992, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 4.063809424472797, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.029795880103947594, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 5.630994173127478, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 5.1086146407806865, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": 3.601176521263643, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 5.451072788423554, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 5.158100915373215, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 3.324246403354797, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 6.1290783809820235, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 5.900694848610817, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 3.9775012177139013, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 5.776702441877219, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 5.433520471039357, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.0658696734379375, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.10764957793359685, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 1.8146941311447389, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.1490667878234352, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.003238257752983392, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -1.1124061834450978, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": 3.1453407050769484, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 2.8824331547297675, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.7528519266774695, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 1.4011436692746244, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 4.456211089334324, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 3.0336926843872583, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 3.387480139162705, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": 2.3726710708286567, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.9092344797024997, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 5.910853781570541, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.02145856929009738, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 3.1491138529867637, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 4.339011094817089, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 3.998257448689287, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 2.986754504842179, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 3.7230595085829528, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": 0.017813206405905304, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 6.626967084842634, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 6.9968035172164935, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 5.398771190014916, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 6.679871463038464, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 3.301384133577125, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 4.938491124508558, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 3.560227323591795, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 3.2913887871561567, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 3.9365807945092595, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.03030822275433241, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.4238, \"times_seen\": 2.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"D\", \"escape\": -0.006960082098913793, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2586, \"times_seen\": 9.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": -0.016983788073247807, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.1014, \"times_seen\": 12.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.09860217240331291, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2543, \"times_seen\": 80.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"N\", \"escape\": 0.044695774588294976, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.3976, \"times_seen\": 23.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"S\", \"escape\": 0.42454925660687665, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.4215, \"times_seen\": 9.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"V\", \"escape\": 3.3339843635593125, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.095, \"times_seen\": 5.0}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.00875184387455288, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -2.6941, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 1.2022660589898748, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": 0.084433226970637, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.024790285647301902, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -1.2399737883008233, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 6.327675433070906, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 5.706819510130076, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.04901797470105145, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": 1.6502057672122266, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.0316, \"times_seen\": 30.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"L\", \"escape\": 0.06470225882441528, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.5391, \"times_seen\": 5.0}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"-\", \"escape\": 0.05528621899928093, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": 0.042205617460028336, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": 0.9978127612427541, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": -0.03170746988406976, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": -0.01847093949272139, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.9028575191921331, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": -0.07230632197069453, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.03616152328648847, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.07866464108235376, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.01579370170150462, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.09091326855928183, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": -0.03791333106622611, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.10094672960033615, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.9146915645192252, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.1578990223083731, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.6848171270303757, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": 2.3858578355583213, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.02000079016450145, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.7186709202437289, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": 0.019576487350403526, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.1313, \"times_seen\": 22.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"*\", \"escape\": -0.0011904090429413622, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": 0.016473952366292576, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"C\", \"escape\": -0.0023484564474220496, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -1.9525, \"times_seen\": 1.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"F\", \"escape\": 0.16694021426571107, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.4406, \"times_seen\": 13.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"H\", \"escape\": -0.04337477246832893, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.9062, \"times_seen\": 9.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"R\", \"escape\": -0.007128442259501085, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.6085, \"times_seen\": 3.0}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"*\", \"escape\": 0.00348527491046708, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -2.3815, \"times_seen\": 1.0}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"G\", \"escape\": -0.005951462841764855, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0722, \"times_seen\": 2.0}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"K\", \"escape\": -0.005448050843341368, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0305, \"times_seen\": 3.0}, {\"site\": 434, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 435, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 437, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 438, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 439, \"wildtype\": \"D\", \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 446, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 448, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 450, \"wildtype\": \"Y\", \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"wildtype\": \"R\", \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"wildtype\": null, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.9261, \"times_seen\": null}, {\"site\": 435, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.9463, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 437, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 438, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 439, \"wildtype\": null, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 446, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 447, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.1636, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.5122, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -0.4405, \"times_seen\": null}, {\"site\": 448, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.1395, \"times_seen\": null}, {\"site\": 450, \"wildtype\": null, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.1241, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 451, \"wildtype\": null, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.2549, \"times_seen\": null}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-4a34a2ae7098d9d68cc4385b731fce96\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_8\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_7\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-8619292b1176ffbe5cae456f236558df\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_12 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_14\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-8619292b1176ffbe5cae456f236558df\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_12 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-5a734829eb65fe055d39df369477cf3c\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_9\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-8619292b1176ffbe5cae456f236558df\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_12 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-8619292b1176ffbe5cae456f236558df\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_12 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 6.9910636155979695, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-8619292b1176ffbe5cae456f236558df\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_12 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-8619292b1176ffbe5cae456f236558df\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_11 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_12 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-5a734829eb65fe055d39df369477cf3c\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_15\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_8\", \"view_7\", \"view_9\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_7\"]}, {\"name\": \"param_14\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_7\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -1.2395902295705836], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_8\", \"view_7\", \"view_9\"]}, {\"name\": \"param_11\", \"bind\": {\"input\": \"range\", \"max\": 0.8558, \"min\": -3.2612, \"name\": \"minimum functional effect\"}, \"value\": -3.3409}, {\"name\": \"param_12\", \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": 1}, {\"name\": \"param_13\", \"bind\": {\"input\": \"range\", \"max\": 6.9910636155979695, \"min\": -1.2395902295705836, \"name\": \"minimum max of escape at site\"}, \"value\": -1.2395902295705836}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-4a34a2ae7098d9d68cc4385b731fce96\": [{\"site\": 434, \"_stat_site_order\": 0}, {\"site\": 435, \"_stat_site_order\": 1}, {\"site\": 436, \"_stat_site_order\": 2}, {\"site\": 437, \"_stat_site_order\": 3}, {\"site\": 438, \"_stat_site_order\": 4}, {\"site\": 439, \"_stat_site_order\": 5}, {\"site\": 440, \"_stat_site_order\": 6}, {\"site\": 441, \"_stat_site_order\": 7}, {\"site\": 442, \"_stat_site_order\": 8}, {\"site\": 443, \"_stat_site_order\": 9}, {\"site\": 444, \"_stat_site_order\": 10}, {\"site\": 445, \"_stat_site_order\": 11}, {\"site\": 446, \"_stat_site_order\": 12}, {\"site\": 447, \"_stat_site_order\": 13}, {\"site\": 448, \"_stat_site_order\": 14}, {\"site\": 449, \"_stat_site_order\": 15}, {\"site\": 450, \"_stat_site_order\": 16}, {\"site\": 451, \"_stat_site_order\": 17}], \"data-5a734829eb65fe055d39df369477cf3c\": [{\"site\": 434, \"mutant\": \"K\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.9261, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 434, \"mutant\": \"S\", \"escape\": -0.0036011210968362453, \"epitope\": \"epitope 1\", \"reference_site\": \"437\", \"functional effect\": -2.5419, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"-\", \"escape\": 1.5341444868763554, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.4674, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"A\", \"escape\": 0.0491004154741001, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.3883, \"times_seen\": 5.0}, {\"site\": 435, \"mutant\": \"C\", \"escape\": 1.9430764553881392, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -0.1849, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"G\", \"escape\": -0.013518840882798647, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.9279, \"times_seen\": 2.0}, {\"site\": 435, \"mutant\": \"I\", \"escape\": 0.022887706712292566, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.7564, \"times_seen\": 1.0}, {\"site\": 435, \"mutant\": \"N\", \"escape\": 2.9978861059507937, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.0882, \"times_seen\": 8.0}, {\"site\": 435, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -2.9463, \"times_seen\": null}, {\"site\": 435, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 435, \"mutant\": \"T\", \"escape\": 0.05000011836968374, \"epitope\": \"epitope 1\", \"reference_site\": \"438\", \"functional effect\": -1.1017, \"times_seen\": 6.0}, {\"site\": 436, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"A\", \"escape\": 0.016427143526268763, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"D\", \"escape\": -0.02710013345112194, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"F\", \"escape\": 3.832582787896979, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"mutant\": \"G\", \"escape\": -0.006256425652795945, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"H\", \"escape\": 0.03431372346877369, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"I\", \"escape\": -0.007500558674593125, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"K\", \"escape\": 2.6665685717902377, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"mutant\": \"L\", \"escape\": 0.049014875473202844, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"mutant\": \"M\", \"escape\": -0.0008700304490536247, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"Q\", \"escape\": 0.019096661658557862, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"mutant\": \"R\", \"escape\": 0.022321343659805398, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"S\", \"escape\": 3.841301635776083, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"mutant\": \"T\", \"escape\": 4.2685953534301175, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"V\", \"escape\": 0.005009097771370356, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"W\", \"escape\": 0.016481787270732528, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"mutant\": \"Y\", \"escape\": 4.831417215856227, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 437, \"mutant\": \"*\", \"escape\": -0.43239155163434884, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.7496, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 437, \"mutant\": \"A\", \"escape\": -0.01612973387200665, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.028, \"times_seen\": 21.0}, {\"site\": 437, \"mutant\": \"C\", \"escape\": 0.0021528630841421963, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -2.979, \"times_seen\": 1.0}, {\"site\": 437, \"mutant\": \"D\", \"escape\": 2.072148802120876, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1224, \"times_seen\": 14.0}, {\"site\": 437, \"mutant\": \"E\", \"escape\": -0.027912233257521114, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.3113, \"times_seen\": 15.0}, {\"site\": 437, \"mutant\": \"F\", \"escape\": 2.0717051386142855, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.206, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"G\", \"escape\": -0.025087624400436485, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0017, \"times_seen\": 24.0}, {\"site\": 437, \"mutant\": \"H\", \"escape\": 0.442001192767205, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.221, \"times_seen\": 12.0}, {\"site\": 437, \"mutant\": \"I\", \"escape\": -0.018195677349063313, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8004, \"times_seen\": 13.0}, {\"site\": 437, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 437, \"mutant\": \"L\", \"escape\": 0.06668710845978768, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.8499, \"times_seen\": 18.0}, {\"site\": 437, \"mutant\": \"M\", \"escape\": 0.02104416542401308, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.0401, \"times_seen\": 10.0}, {\"site\": 437, \"mutant\": \"N\", \"escape\": -0.04472080009416803, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2118, \"times_seen\": 36.0}, {\"site\": 437, \"mutant\": \"P\", \"escape\": 0.036938368307112154, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.534, \"times_seen\": 8.0}, {\"site\": 437, \"mutant\": \"Q\", \"escape\": 0.010580494466850863, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.1906, \"times_seen\": 16.0}, {\"site\": 437, \"mutant\": \"R\", \"escape\": -0.07271886969535121, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.1206, \"times_seen\": 36.0}, {\"site\": 437, \"mutant\": \"S\", \"escape\": 0.03962198683342554, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.2856, \"times_seen\": 44.0}, {\"site\": 437, \"mutant\": \"T\", \"escape\": -0.040917580438122575, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": 0.0087, \"times_seen\": 29.0}, {\"site\": 437, \"mutant\": \"V\", \"escape\": 1.5370541625533614, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.4789, \"times_seen\": 13.0}, {\"site\": 437, \"mutant\": \"W\", \"escape\": 0.006973859553402811, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -1.2464, \"times_seen\": 5.0}, {\"site\": 437, \"mutant\": \"Y\", \"escape\": 0.025723488302595042, \"epitope\": \"epitope 1\", \"reference_site\": \"440\", \"functional effect\": -0.2806, \"times_seen\": 16.0}, {\"site\": 438, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 438, \"mutant\": \"F\", \"escape\": 0.02647816813481393, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.1303, \"times_seen\": 10.0}, {\"site\": 438, \"mutant\": \"I\", \"escape\": -0.0008405549647014136, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0594, \"times_seen\": 19.0}, {\"site\": 438, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 438, \"mutant\": \"M\", \"escape\": -0.0053318954744334115, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.0273, \"times_seen\": 3.0}, {\"site\": 438, \"mutant\": \"P\", \"escape\": -0.026724615483474563, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -2.2021, \"times_seen\": 6.0}, {\"site\": 438, \"mutant\": \"Q\", \"escape\": -0.006271509311207683, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -1.4385, \"times_seen\": 1.0}, {\"site\": 438, \"mutant\": \"R\", \"escape\": -0.009767884753971967, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": -0.74, \"times_seen\": 7.0}, {\"site\": 438, \"mutant\": \"V\", \"escape\": -0.002336955752521854, \"epitope\": \"epitope 1\", \"reference_site\": \"441\", \"functional effect\": 0.3662, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.7523, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"D\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"E\", \"escape\": 0.037320976751014985, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -1.6793, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.0, \"times_seen\": null}, {\"site\": 439, \"mutant\": \"N\", \"escape\": -0.007310508092986951, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -2.4152, \"times_seen\": 1.0}, {\"site\": 439, \"mutant\": \"V\", \"escape\": 0.017156480692227263, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -0.8693, \"times_seen\": 2.0}, {\"site\": 439, \"mutant\": \"Y\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"442\", \"functional effect\": -3.1475, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"A\", \"escape\": -0.0018508962770346098, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"F\", \"escape\": 0.02547891296088903, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"G\", \"escape\": 1.4563559371982857, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"I\", \"escape\": 0.028627963460388005, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"N\", \"escape\": 4.061554094319634, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"mutant\": \"R\", \"escape\": 0.028944033712633876, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"E\", \"escape\": 5.63100423612968, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"I\", \"escape\": 5.105792618876912, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"L\", \"escape\": 3.5897397921326712, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"mutant\": \"M\", \"escape\": 5.446932297015271, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"mutant\": \"N\", \"escape\": 5.1608551404122265, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"R\", \"escape\": 3.319825656559487, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"mutant\": \"T\", \"escape\": 6.123173736421349, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"mutant\": \"A\", \"escape\": 5.902019566322775, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"mutant\": \"E\", \"escape\": 3.9793199775315413, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"mutant\": \"F\", \"escape\": 5.777817042399776, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"mutant\": \"G\", \"escape\": 5.435605704646021, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"I\", \"escape\": 0.06486968350891383, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"mutant\": \"L\", \"escape\": 0.10381107713727365, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"M\", \"escape\": 1.8121877468603933, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 442, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"*\", \"escape\": 0.01704085001058422, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 443, \"mutant\": \"A\", \"escape\": -0.13215564266637744, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"mutant\": \"C\", \"escape\": 0.0030289614883239994, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"mutant\": \"D\", \"escape\": -1.1178473291233153, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"mutant\": \"E\", \"escape\": 3.144212005693318, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"F\", \"escape\": 2.8850751630196485, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"mutant\": \"G\", \"escape\": -0.7636926075869136, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"mutant\": \"H\", \"escape\": 1.4036104483163871, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"mutant\": \"I\", \"escape\": 4.465674215902675, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"mutant\": \"K\", \"escape\": 3.035343859400086, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"L\", \"escape\": 3.3899456114186157, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"mutant\": \"M\", \"escape\": 2.3698456367836256, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"mutant\": \"N\", \"escape\": -0.9090323970409143, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"mutant\": \"P\", \"escape\": 5.917862827319068, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"mutant\": \"Q\", \"escape\": -0.02130403599780089, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"mutant\": \"R\", \"escape\": 3.151992191693694, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"T\", \"escape\": 4.338902376103604, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"mutant\": \"V\", \"escape\": 4.002063487234195, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"mutant\": \"W\", \"escape\": 2.9877229181564315, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"mutant\": \"Y\", \"escape\": 3.7215649679543388, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 444, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"D\", \"escape\": 6.640133123584938, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"R\", \"escape\": 6.9910636155979695, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"mutant\": \"S\", \"escape\": 5.399063074777597, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"mutant\": \"V\", \"escape\": 6.678236397419462, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"D\", \"escape\": 3.3027935937430053, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"K\", \"escape\": 4.941555780752706, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"S\", \"escape\": 3.556761198509068, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"mutant\": \"T\", \"escape\": 3.2982285834944176, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"mutant\": \"Y\", \"escape\": 3.9417863964845368, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 446, \"mutant\": \"*\", \"escape\": 0.008445034238556406, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -2.6941, \"times_seen\": 1.0}, {\"site\": 446, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 446, \"mutant\": \"C\", \"escape\": -0.0307290815327942, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.4238, \"times_seen\": 2.0}, {\"site\": 446, \"mutant\": \"D\", \"escape\": -0.0070845570883118466, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2586, \"times_seen\": 9.0}, {\"site\": 446, \"mutant\": \"F\", \"escape\": -0.01700233426493981, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.1014, \"times_seen\": 12.0}, {\"site\": 446, \"mutant\": \"H\", \"escape\": -0.0976506885387023, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.2543, \"times_seen\": 80.0}, {\"site\": 446, \"mutant\": \"N\", \"escape\": 0.04887441661667216, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.3976, \"times_seen\": 23.0}, {\"site\": 446, \"mutant\": \"S\", \"escape\": 0.3181864735443787, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.4215, \"times_seen\": 9.0}, {\"site\": 446, \"mutant\": \"V\", \"escape\": 3.3332591031449126, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": -0.095, \"times_seen\": 5.0}, {\"site\": 446, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"449\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"D\", \"escape\": 1.2022407453719384, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"mutant\": \"G\", \"escape\": 0.14906613288498383, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"H\", \"escape\": -0.02331482548619225, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"K\", \"escape\": -1.2395902295705836, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.1636, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"S\", \"escape\": 6.319726305393131, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"mutant\": \"T\", \"escape\": 5.710660039507474, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"mutant\": \"Y\", \"escape\": 0.049310057235704974, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 448, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.5122, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"-\", \"escape\": 0.05810435917243956, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 448, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.3177, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -0.4405, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"H\", \"escape\": 1.650666746250599, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.0316, \"times_seen\": 30.0}, {\"site\": 448, \"mutant\": \"L\", \"escape\": 0.06352754936609514, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -1.5391, \"times_seen\": 5.0}, {\"site\": 448, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": -2.1395, \"times_seen\": null}, {\"site\": 448, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"451\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"mutant\": \"*\", \"escape\": -0.0013112829486073168, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"mutant\": \"-\", \"escape\": 0.016457986386659185, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 449, \"mutant\": \"A\", \"escape\": 0.04449928696971482, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"mutant\": \"C\", \"escape\": 0.991289755368235, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"mutant\": \"D\", \"escape\": -0.03152440926541618, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"mutant\": \"E\", \"escape\": -0.018631306830825742, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"F\", \"escape\": 0.904464328802799, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"mutant\": \"G\", \"escape\": -0.07195898031198282, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"mutant\": \"H\", \"escape\": -0.03690237152744968, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"mutant\": \"I\", \"escape\": -0.07831356105501613, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"mutant\": \"K\", \"escape\": -0.014976751894210383, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"mutant\": \"M\", \"escape\": 0.08853385749800997, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"mutant\": \"N\", \"escape\": -0.03781229992920182, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"mutant\": \"P\", \"escape\": 0.10137836137218854, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"mutant\": \"Q\", \"escape\": 0.9148281921785856, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"R\", \"escape\": 0.15644970658104815, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"mutant\": \"S\", \"escape\": 0.6830723697409273, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"mutant\": \"T\", \"escape\": 2.3950307069044503, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"V\", \"escape\": -0.020241535039453876, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"mutant\": \"W\", \"escape\": 0.6432546063871584, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"mutant\": \"Y\", \"escape\": 0.01990202091713323, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.1313, \"times_seen\": 22.0}, {\"site\": 450, \"mutant\": \"*\", \"escape\": 0.003474726326575292, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -2.3815, \"times_seen\": 1.0}, {\"site\": 450, \"mutant\": \"C\", \"escape\": -0.0024000944246925873, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -1.9525, \"times_seen\": 1.0}, {\"site\": 450, \"mutant\": \"F\", \"escape\": 0.16709511621115822, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.4406, \"times_seen\": 13.0}, {\"site\": 450, \"mutant\": \"H\", \"escape\": -0.043041248694975554, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.9062, \"times_seen\": 9.0}, {\"site\": 450, \"mutant\": \"N\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -3.2612, \"times_seen\": null}, {\"site\": 450, \"mutant\": \"R\", \"escape\": -0.007123284727517342, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": -0.6085, \"times_seen\": 3.0}, {\"site\": 450, \"mutant\": \"Y\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"453\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -1.6452, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.1241, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"G\", \"escape\": -0.005916203101142011, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0722, \"times_seen\": 2.0}, {\"site\": 451, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -2.9709, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"K\", \"escape\": -0.0054773434802644965, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.0305, \"times_seen\": 3.0}, {\"site\": 451, \"mutant\": \"R\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 451, \"mutant\": \"T\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"454\", \"functional effect\": -3.2549, \"times_seen\": null}], \"data-8619292b1176ffbe5cae456f236558df\": [{\"site\": 434, \"wildtype\": \"N\", \"_stat_site_order\": 0}, {\"site\": 435, \"wildtype\": \"S\", \"_stat_site_order\": 1}, {\"site\": 436, \"wildtype\": \"N\", \"_stat_site_order\": 2}, {\"site\": 437, \"wildtype\": \"K\", \"_stat_site_order\": 3}, {\"site\": 438, \"wildtype\": \"L\", \"_stat_site_order\": 4}, {\"site\": 439, \"wildtype\": \"D\", \"_stat_site_order\": 5}, {\"site\": 440, \"wildtype\": \"S\", \"_stat_site_order\": 6}, {\"site\": 441, \"wildtype\": \"K\", \"_stat_site_order\": 7}, {\"site\": 442, \"wildtype\": \"V\", \"_stat_site_order\": 8}, {\"site\": 443, \"wildtype\": \"S\", \"_stat_site_order\": 9}, {\"site\": 444, \"wildtype\": \"G\", \"_stat_site_order\": 10}, {\"site\": 445, \"wildtype\": \"N\", \"_stat_site_order\": 11}, {\"site\": 446, \"wildtype\": \"Y\", \"_stat_site_order\": 12}, {\"site\": 447, \"wildtype\": \"N\", \"_stat_site_order\": 13}, {\"site\": 448, \"wildtype\": \"Y\", \"_stat_site_order\": 14}, {\"site\": 449, \"wildtype\": \"L\", \"_stat_site_order\": 15}, {\"site\": 450, \"wildtype\": \"Y\", \"_stat_site_order\": 16}, {\"site\": 451, \"wildtype\": \"R\", \"_stat_site_order\": 17}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -1167,13 +1090,6 @@
    "execution_count": 12,
    "id": "f9d15bf6-c67b-46aa-9f69-96b97133e701",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:36:03.131534Z",
-     "iopub.status.busy": "2023-08-18T19:36:03.131192Z",
-     "iopub.status.idle": "2023-08-18T19:36:04.069149Z",
-     "shell.execute_reply": "2023-08-18T19:36:04.068142Z",
-     "shell.execute_reply.started": "2023-08-18T19:36:03.131508Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -1182,28 +1098,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-0203348ff24449f0a2218202fe7ae204.vega-embed {\n",
+       "  #altair-viz-08a4af881d4949c29e689458c7ecad1a.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-0203348ff24449f0a2218202fe7ae204.vega-embed details,\n",
-       "  #altair-viz-0203348ff24449f0a2218202fe7ae204.vega-embed details summary {\n",
+       "  #altair-viz-08a4af881d4949c29e689458c7ecad1a.vega-embed details,\n",
+       "  #altair-viz-08a4af881d4949c29e689458c7ecad1a.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-0203348ff24449f0a2218202fe7ae204\"></div>\n",
+       "<div id=\"altair-viz-08a4af881d4949c29e689458c7ecad1a\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-0203348ff24449f0a2218202fe7ae204\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-0203348ff24449f0a2218202fe7ae204\");\n",
+       "    if (outputDiv.id !== \"altair-viz-08a4af881d4949c29e689458c7ecad1a\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-08a4af881d4949c29e689458c7ecad1a\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -1239,12 +1155,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_11\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_10\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_17['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_18['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_19\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_17['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_18['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-4d9d5737ed77cefc5eba328dfbc0618f\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_12\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_17['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_18['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_17['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_18['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 6.9968035172164935, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_17['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_18['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"key\": \"site\", \"fields\": [\"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16['cutoff'] - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['times_seen'] >= (param_17['cutoff'] - 1e-06)) || (!isFinite(datum['times_seen'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2399737883008233,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_18['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-4d9d5737ed77cefc5eba328dfbc0618f\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_20\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_11\", \"view_10\", \"view_12\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_10\"]}, {\"name\": \"param_19\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_10\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -1.2399737883008233], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_11\", \"view_10\", \"view_12\"]}, {\"name\": \"param_16\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 0.8558, \"min\": -3.0442, \"name\": \"minimum functional effect\"}, \"value\": [{\"cutoff\": -3.3409}], \"views\": [\"view_11\", \"view_10\", \"view_12\"]}, {\"name\": \"param_17\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": [{\"cutoff\": 1}], \"views\": [\"view_11\", \"view_10\", \"view_12\"]}, {\"name\": \"param_18\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 6.9968035172164935, \"min\": -1.2399737883008233, \"name\": \"minimum max of escape at site\"}, \"value\": [{\"cutoff\": -1.2399737883008233}], \"views\": [\"view_11\", \"view_10\", \"view_12\"]}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-419ebc4684f727a1b1976f76afc6bf7c\": [{\"site\": 436, \"_stat_site_order\": 0}, {\"site\": 440, \"_stat_site_order\": 1}, {\"site\": 441, \"_stat_site_order\": 2}, {\"site\": 442, \"_stat_site_order\": 3}, {\"site\": 443, \"_stat_site_order\": 4}, {\"site\": 444, \"_stat_site_order\": 5}, {\"site\": 445, \"_stat_site_order\": 6}, {\"site\": 447, \"_stat_site_order\": 7}, {\"site\": 449, \"_stat_site_order\": 8}], \"data-4d9d5737ed77cefc5eba328dfbc0618f\": [{\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"A\", \"escape\": 0.016876975686188816, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": -0.027074082227422067, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"F\", \"escape\": 3.839339491084656, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": -0.0061703486041247, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": 0.03499239047798595, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"I\", \"escape\": -0.007452001126785125, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 2.6638838987662563, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"L\", \"escape\": 0.04943721062257711, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"M\", \"escape\": -0.001175724486255462, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Q\", \"escape\": 0.019514357374329702, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"R\", \"escape\": 0.02288760395355997, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 3.842039706589607, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 4.280575467950762, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"V\", \"escape\": 0.005026561001255139, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"W\", \"escape\": 0.01704523720368397, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 4.840163734877134, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.0014282848810145583, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 0.02547035101203864, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": 1.4854199203475613, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 0.029425100714127992, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": 4.063809424472797, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 0.029795880103947594, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"E\", \"escape\": 5.630994173127478, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"I\", \"escape\": 5.1086146407806865, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"L\", \"escape\": 3.601176521263643, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"M\", \"escape\": 5.451072788423554, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"N\", \"escape\": 5.158100915373215, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"R\", \"escape\": 3.324246403354797, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"T\", \"escape\": 6.1290783809820235, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"A\", \"escape\": 5.900694848610817, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"E\", \"escape\": 3.9775012177139013, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"F\", \"escape\": 5.776702441877219, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"G\", \"escape\": 5.433520471039357, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"I\", \"escape\": 0.0658696734379375, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"L\", \"escape\": 0.10764957793359685, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"M\", \"escape\": 1.8146941311447389, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"A\", \"escape\": -0.1490667878234352, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"C\", \"escape\": 0.003238257752983392, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"D\", \"escape\": -1.1124061834450978, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"E\", \"escape\": 3.1453407050769484, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"F\", \"escape\": 2.8824331547297675, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"G\", \"escape\": -0.7528519266774695, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"H\", \"escape\": 1.4011436692746244, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"I\", \"escape\": 4.456211089334324, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"K\", \"escape\": 3.0336926843872583, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"L\", \"escape\": 3.387480139162705, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"M\", \"escape\": 2.3726710708286567, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"N\", \"escape\": -0.9092344797024997, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"P\", \"escape\": 5.910853781570541, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Q\", \"escape\": -0.02145856929009738, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"R\", \"escape\": 3.1491138529867637, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"T\", \"escape\": 4.339011094817089, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"V\", \"escape\": 3.998257448689287, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"W\", \"escape\": 2.986754504842179, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"Y\", \"escape\": 3.7230595085829528, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"*\", \"escape\": 0.017813206405905304, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"D\", \"escape\": 6.626967084842634, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"R\", \"escape\": 6.9968035172164935, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"S\", \"escape\": 5.398771190014916, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"V\", \"escape\": 6.679871463038464, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 3.301384133577125, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": 4.938491124508558, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 3.560227323591795, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 3.2913887871561567, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 3.9365807945092595, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"D\", \"escape\": 1.2022660589898748, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"G\", \"escape\": 0.084433226970637, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"H\", \"escape\": -0.024790285647301902, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"K\", \"escape\": -1.2399737883008233, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"S\", \"escape\": 6.327675433070906, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"T\", \"escape\": 5.706819510130076, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"Y\", \"escape\": 0.04901797470105145, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"A\", \"escape\": 0.042205617460028336, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"C\", \"escape\": 0.9978127612427541, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"D\", \"escape\": -0.03170746988406976, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"E\", \"escape\": -0.01847093949272139, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"F\", \"escape\": 0.9028575191921331, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"G\", \"escape\": -0.07230632197069453, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"H\", \"escape\": -0.03616152328648847, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"I\", \"escape\": -0.07866464108235376, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"K\", \"escape\": -0.01579370170150462, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"M\", \"escape\": 0.09091326855928183, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"N\", \"escape\": -0.03791333106622611, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"P\", \"escape\": 0.10094672960033615, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Q\", \"escape\": 0.9146915645192252, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"R\", \"escape\": 0.1578990223083731, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"S\", \"escape\": 0.6848171270303757, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"T\", \"escape\": 2.3858578355583213, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"V\", \"escape\": -0.02000079016450145, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"W\", \"escape\": 0.7186709202437289, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"Y\", \"escape\": 0.019576487350403526, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.1313, \"times_seen\": 22.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"*\", \"escape\": -0.0011904090429413622, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"-\", \"escape\": 0.016473952366292576, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 436, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 440, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"wildtype\": \"K\", \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 442, \"wildtype\": \"V\", \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"wildtype\": \"S\", \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"wildtype\": \"G\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"wildtype\": \"N\", \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"wildtype\": \"L\", \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"wildtype\": null, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"wildtype\": null, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"wildtype\": null, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"wildtype\": null, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 447, \"wildtype\": null, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.1636, \"times_seen\": null}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-419ebc4684f727a1b1976f76afc6bf7c\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_11\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_10\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-37bdd5285427e8605aa56b151b88aeeb\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_17 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_18 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_19\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"epitope 1\"], \"range\": [\"#0072B2\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"quantitative\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-37bdd5285427e8605aa56b151b88aeeb\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_17 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_18 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-420c26d4f89ab7cc3a483c153a017383\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_12\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-37bdd5285427e8605aa56b151b88aeeb\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_17 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_18 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-37bdd5285427e8605aa56b151b88aeeb\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_17 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_18 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 6.9910636155979695, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"reference_site\", \"type\": \"nominal\"}, {\"field\": \"functional effect\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"times_seen\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-37bdd5285427e8605aa56b151b88aeeb\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_17 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_18 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\", \"-\", \"*\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-37bdd5285427e8605aa56b151b88aeeb\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['functional effect']),datum['functional effect'],NaN)\", \"as\": \"functional effect\"}, {\"calculate\": \"if(isFinite(datum['times_seen']),datum['times_seen'],NaN)\", \"as\": \"times_seen\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"(datum['functional effect'] <= (param_16 - 1e-06))\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['times_seen'] >= (param_17 - 1e-06)) || (!isFinite(datum['times_seen']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],-1.2395902295705836,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_18 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_20\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-420c26d4f89ab7cc3a483c153a017383\"}, \"resolve\": {\"scale\": {\"color\": \"shared\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_20\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_11\", \"view_10\", \"view_12\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_10\"]}, {\"name\": \"param_19\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_10\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, -1.2395902295705836], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_11\", \"view_10\", \"view_12\"]}, {\"name\": \"param_16\", \"bind\": {\"input\": \"range\", \"max\": 0.8558, \"min\": -3.0442, \"name\": \"minimum functional effect\"}, \"value\": -3.3409}, {\"name\": \"param_17\", \"bind\": {\"input\": \"range\", \"max\": 50, \"min\": 1.0, \"name\": \"minimum times_seen\"}, \"value\": 1}, {\"name\": \"param_18\", \"bind\": {\"input\": \"range\", \"max\": 6.9910636155979695, \"min\": -1.2395902295705836, \"name\": \"minimum max of escape at site\"}, \"value\": -1.2395902295705836}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-419ebc4684f727a1b1976f76afc6bf7c\": [{\"site\": 436, \"_stat_site_order\": 0}, {\"site\": 440, \"_stat_site_order\": 1}, {\"site\": 441, \"_stat_site_order\": 2}, {\"site\": 442, \"_stat_site_order\": 3}, {\"site\": 443, \"_stat_site_order\": 4}, {\"site\": 444, \"_stat_site_order\": 5}, {\"site\": 445, \"_stat_site_order\": 6}, {\"site\": 447, \"_stat_site_order\": 7}, {\"site\": 449, \"_stat_site_order\": 8}], \"data-420c26d4f89ab7cc3a483c153a017383\": [{\"site\": 436, \"mutant\": \"*\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -2.4102, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"A\", \"escape\": 0.016427143526268763, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.148, \"times_seen\": 9.0}, {\"site\": 436, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0442, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"D\", \"escape\": -0.02710013345112194, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.3936, \"times_seen\": 14.0}, {\"site\": 436, \"mutant\": \"E\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.8776, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"F\", \"escape\": 3.832582787896979, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2249, \"times_seen\": 5.0}, {\"site\": 436, \"mutant\": \"G\", \"escape\": -0.006256425652795945, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.9668, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"H\", \"escape\": 0.03431372346877369, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0105, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"I\", \"escape\": -0.007500558674593125, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.1322, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"K\", \"escape\": 2.6665685717902377, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2087, \"times_seen\": 21.0}, {\"site\": 436, \"mutant\": \"L\", \"escape\": 0.049014875473202844, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6398, \"times_seen\": 13.0}, {\"site\": 436, \"mutant\": \"M\", \"escape\": -0.0008700304490536247, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.6036, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"P\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -3.0037, \"times_seen\": null}, {\"site\": 436, \"mutant\": \"Q\", \"escape\": 0.019096661658557862, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.2547, \"times_seen\": 2.0}, {\"site\": 436, \"mutant\": \"R\", \"escape\": 0.022321343659805398, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4304, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"S\", \"escape\": 3.841301635776083, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.6313, \"times_seen\": 12.0}, {\"site\": 436, \"mutant\": \"T\", \"escape\": 4.2685953534301175, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.5796, \"times_seen\": 15.0}, {\"site\": 436, \"mutant\": \"V\", \"escape\": 0.005009097771370356, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.2471, \"times_seen\": 4.0}, {\"site\": 436, \"mutant\": \"W\", \"escape\": 0.016481787270732528, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -1.4862, \"times_seen\": 1.0}, {\"site\": 436, \"mutant\": \"Y\", \"escape\": 4.831417215856227, \"epitope\": \"epitope 1\", \"reference_site\": \"439\", \"functional effect\": -0.7519, \"times_seen\": 7.0}, {\"site\": 440, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6366, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"A\", \"escape\": -0.0018508962770346098, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.2301, \"times_seen\": 14.0}, {\"site\": 440, \"mutant\": \"D\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.8418, \"times_seen\": null}, {\"site\": 440, \"mutant\": \"F\", \"escape\": 0.02547891296088903, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9255, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"G\", \"escape\": 1.4563559371982857, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.4532, \"times_seen\": 3.0}, {\"site\": 440, \"mutant\": \"I\", \"escape\": 0.028627963460388005, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.9676, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"N\", \"escape\": 4.061554094319634, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -0.6798, \"times_seen\": 32.0}, {\"site\": 440, \"mutant\": \"R\", \"escape\": 0.028944033712633876, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": -2.0048, \"times_seen\": 1.0}, {\"site\": 440, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"443\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"E\", \"escape\": 5.63100423612968, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.1312, \"times_seen\": 24.0}, {\"site\": 441, \"mutant\": \"G\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -1.1166, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"I\", \"escape\": 5.105792618876912, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.4985, \"times_seen\": 8.0}, {\"site\": 441, \"mutant\": \"K\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"L\", \"escape\": 3.5897397921326712, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.2043, \"times_seen\": 10.0}, {\"site\": 441, \"mutant\": \"M\", \"escape\": 5.446932297015271, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.1108, \"times_seen\": 96.0}, {\"site\": 441, \"mutant\": \"N\", \"escape\": 5.1608551404122265, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.2503, \"times_seen\": 62.0}, {\"site\": 441, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.8558, \"times_seen\": null}, {\"site\": 441, \"mutant\": \"R\", \"escape\": 3.319825656559487, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": -0.087, \"times_seen\": 87.0}, {\"site\": 441, \"mutant\": \"T\", \"escape\": 6.123173736421349, \"epitope\": \"epitope 1\", \"reference_site\": \"444\", \"functional effect\": 0.0425, \"times_seen\": 17.0}, {\"site\": 442, \"mutant\": \"A\", \"escape\": 5.902019566322775, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.0472, \"times_seen\": 22.0}, {\"site\": 442, \"mutant\": \"E\", \"escape\": 3.9793199775315413, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.219, \"times_seen\": 1.0}, {\"site\": 442, \"mutant\": \"F\", \"escape\": 5.777817042399776, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.184, \"times_seen\": 16.0}, {\"site\": 442, \"mutant\": \"G\", \"escape\": 5.435605704646021, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0278, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"I\", \"escape\": 0.06486968350891383, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.1605, \"times_seen\": 18.0}, {\"site\": 442, \"mutant\": \"L\", \"escape\": 0.10381107713727365, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.2242, \"times_seen\": 8.0}, {\"site\": 442, \"mutant\": \"M\", \"escape\": 1.8121877468603933, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": -0.256, \"times_seen\": 15.0}, {\"site\": 442, \"mutant\": \"V\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"445\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"*\", \"escape\": 0.01704085001058422, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.3974, \"times_seen\": 1.0}, {\"site\": 443, \"mutant\": \"A\", \"escape\": -0.13215564266637744, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0119, \"times_seen\": 73.0}, {\"site\": 443, \"mutant\": \"C\", \"escape\": 0.0030289614883239994, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -2.7016, \"times_seen\": 5.0}, {\"site\": 443, \"mutant\": \"D\", \"escape\": -1.1178473291233153, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1929, \"times_seen\": 65.0}, {\"site\": 443, \"mutant\": \"E\", \"escape\": 3.144212005693318, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.1094, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"F\", \"escape\": 2.8850751630196485, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3944, \"times_seen\": 16.0}, {\"site\": 443, \"mutant\": \"G\", \"escape\": -0.7636926075869136, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0684, \"times_seen\": 86.0}, {\"site\": 443, \"mutant\": \"H\", \"escape\": 1.4036104483163871, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2369, \"times_seen\": 12.0}, {\"site\": 443, \"mutant\": \"I\", \"escape\": 4.465674215902675, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.6172, \"times_seen\": 23.0}, {\"site\": 443, \"mutant\": \"K\", \"escape\": 3.035343859400086, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.2569, \"times_seen\": 20.0}, {\"site\": 443, \"mutant\": \"L\", \"escape\": 3.3899456114186157, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.3855, \"times_seen\": 41.0}, {\"site\": 443, \"mutant\": \"M\", \"escape\": 2.3698456367836256, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.4501, \"times_seen\": 19.0}, {\"site\": 443, \"mutant\": \"N\", \"escape\": -0.9090323970409143, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0745, \"times_seen\": 42.0}, {\"site\": 443, \"mutant\": \"P\", \"escape\": 5.917862827319068, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2853, \"times_seen\": 33.0}, {\"site\": 443, \"mutant\": \"Q\", \"escape\": -0.02130403599780089, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.0238, \"times_seen\": 15.0}, {\"site\": 443, \"mutant\": \"R\", \"escape\": 3.151992191693694, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.9053, \"times_seen\": 80.0}, {\"site\": 443, \"mutant\": \"S\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 443, \"mutant\": \"T\", \"escape\": 4.338902376103604, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": 0.0799, \"times_seen\": 64.0}, {\"site\": 443, \"mutant\": \"V\", \"escape\": 4.002063487234195, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.2571, \"times_seen\": 50.0}, {\"site\": 443, \"mutant\": \"W\", \"escape\": 2.9877229181564315, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -1.21, \"times_seen\": 18.0}, {\"site\": 443, \"mutant\": \"Y\", \"escape\": 3.7215649679543388, \"epitope\": \"epitope 1\", \"reference_site\": \"446\", \"functional effect\": -0.5716, \"times_seen\": 18.0}, {\"site\": 444, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"C\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.5716, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"D\", \"escape\": 6.640133123584938, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.1348, \"times_seen\": 25.0}, {\"site\": 444, \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 444, \"mutant\": \"R\", \"escape\": 6.9910636155979695, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.4413, \"times_seen\": 1.0}, {\"site\": 444, \"mutant\": \"S\", \"escape\": 5.399063074777597, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -0.3742, \"times_seen\": 29.0}, {\"site\": 444, \"mutant\": \"V\", \"escape\": 6.678236397419462, \"epitope\": \"epitope 1\", \"reference_site\": \"447\", \"functional effect\": -1.1816, \"times_seen\": 17.0}, {\"site\": 445, \"mutant\": \"-\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.2646, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"D\", \"escape\": 3.3027935937430053, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.1153, \"times_seen\": 10.0}, {\"site\": 445, \"mutant\": \"I\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -2.9988, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"K\", \"escape\": 4.941555780752706, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.068, \"times_seen\": 12.0}, {\"site\": 445, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"R\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.9581, \"times_seen\": null}, {\"site\": 445, \"mutant\": \"S\", \"escape\": 3.556761198509068, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": 0.0789, \"times_seen\": 30.0}, {\"site\": 445, \"mutant\": \"T\", \"escape\": 3.2982285834944176, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -0.5294, \"times_seen\": 16.0}, {\"site\": 445, \"mutant\": \"Y\", \"escape\": 3.9417863964845368, \"epitope\": \"epitope 1\", \"reference_site\": \"448\", \"functional effect\": -1.2559, \"times_seen\": 11.0}, {\"site\": 447, \"mutant\": \"D\", \"escape\": 1.2022407453719384, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0515, \"times_seen\": 47.0}, {\"site\": 447, \"mutant\": \"G\", \"escape\": 0.14906613288498383, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"H\", \"escape\": -0.02331482548619225, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.4125, \"times_seen\": 1.0}, {\"site\": 447, \"mutant\": \"K\", \"escape\": -1.2395902295705836, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.8705, \"times_seen\": 46.0}, {\"site\": 447, \"mutant\": \"N\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"Q\", \"escape\": null, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": 0.1636, \"times_seen\": null}, {\"site\": 447, \"mutant\": \"S\", \"escape\": 6.319726305393131, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.3652, \"times_seen\": 18.0}, {\"site\": 447, \"mutant\": \"T\", \"escape\": 5.710660039507474, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -0.1156, \"times_seen\": 26.0}, {\"site\": 447, \"mutant\": \"Y\", \"escape\": 0.049310057235704974, \"epitope\": \"epitope 1\", \"reference_site\": \"450\", \"functional effect\": -1.0479, \"times_seen\": 1.0}, {\"site\": 449, \"mutant\": \"*\", \"escape\": -0.0013112829486073168, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6132, \"times_seen\": 2.0}, {\"site\": 449, \"mutant\": \"-\", \"escape\": 0.016457986386659185, \"epitope\": \"epitope 1\", \"reference_site\": null, \"functional effect\": null, \"times_seen\": 1.0}, {\"site\": 449, \"mutant\": \"A\", \"escape\": 0.04449928696971482, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0338, \"times_seen\": 34.0}, {\"site\": 449, \"mutant\": \"C\", \"escape\": 0.991289755368235, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.0392, \"times_seen\": 13.0}, {\"site\": 449, \"mutant\": \"D\", \"escape\": -0.03152440926541618, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -1.6731, \"times_seen\": 10.0}, {\"site\": 449, \"mutant\": \"E\", \"escape\": -0.018631306830825742, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2752, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"F\", \"escape\": 0.904464328802799, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2074, \"times_seen\": 41.0}, {\"site\": 449, \"mutant\": \"G\", \"escape\": -0.07195898031198282, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.3552, \"times_seen\": 39.0}, {\"site\": 449, \"mutant\": \"H\", \"escape\": -0.03690237152744968, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2704, \"times_seen\": 40.0}, {\"site\": 449, \"mutant\": \"I\", \"escape\": -0.07831356105501613, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.4897, \"times_seen\": 22.0}, {\"site\": 449, \"mutant\": \"K\", \"escape\": -0.014976751894210383, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0529, \"times_seen\": 15.0}, {\"site\": 449, \"mutant\": \"L\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.0, \"times_seen\": null}, {\"site\": 449, \"mutant\": \"M\", \"escape\": 0.08853385749800997, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2049, \"times_seen\": 36.0}, {\"site\": 449, \"mutant\": \"N\", \"escape\": -0.03781229992920182, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5561, \"times_seen\": 30.0}, {\"site\": 449, \"mutant\": \"P\", \"escape\": 0.10137836137218854, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -2.6791, \"times_seen\": 8.0}, {\"site\": 449, \"mutant\": \"Q\", \"escape\": 0.9148281921785856, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.2003, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"R\", \"escape\": 0.15644970658104815, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.0184, \"times_seen\": 75.0}, {\"site\": 449, \"mutant\": \"S\", \"escape\": 0.6830723697409273, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.5483, \"times_seen\": 64.0}, {\"site\": 449, \"mutant\": \"T\", \"escape\": 2.3950307069044503, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.6024, \"times_seen\": 47.0}, {\"site\": 449, \"mutant\": \"V\", \"escape\": -0.020241535039453876, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.193, \"times_seen\": 38.0}, {\"site\": 449, \"mutant\": \"W\", \"escape\": 0.6432546063871584, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": -0.2767, \"times_seen\": 33.0}, {\"site\": 449, \"mutant\": \"Y\", \"escape\": 0.01990202091713323, \"epitope\": \"epitope 1\", \"reference_site\": \"452\", \"functional effect\": 0.1313, \"times_seen\": 22.0}], \"data-37bdd5285427e8605aa56b151b88aeeb\": [{\"site\": 436, \"wildtype\": \"N\", \"_stat_site_order\": 0}, {\"site\": 440, \"wildtype\": \"S\", \"_stat_site_order\": 1}, {\"site\": 441, \"wildtype\": \"K\", \"_stat_site_order\": 2}, {\"site\": 442, \"wildtype\": \"V\", \"_stat_site_order\": 3}, {\"site\": 443, \"wildtype\": \"S\", \"_stat_site_order\": 4}, {\"site\": 444, \"wildtype\": \"G\", \"_stat_site_order\": 5}, {\"site\": 445, \"wildtype\": \"N\", \"_stat_site_order\": 6}, {\"site\": 447, \"wildtype\": \"N\", \"_stat_site_order\": 7}, {\"site\": 449, \"wildtype\": \"L\", \"_stat_site_order\": 8}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -1282,13 +1198,6 @@
    "execution_count": 13,
    "id": "aeff75ca",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:36:04.070367Z",
-     "iopub.status.busy": "2023-08-18T19:36:04.070083Z",
-     "iopub.status.idle": "2023-08-18T19:36:04.125481Z",
-     "shell.execute_reply": "2023-08-18T19:36:04.124706Z",
-     "shell.execute_reply.started": "2023-08-18T19:36:04.070345Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -1382,13 +1291,6 @@
    "execution_count": 14,
    "id": "c05b9029-6c4b-4c14-88cd-ed997a32b84a",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-08-18T19:36:04.126725Z",
-     "iopub.status.busy": "2023-08-18T19:36:04.126375Z",
-     "iopub.status.idle": "2023-08-18T19:36:04.130774Z",
-     "shell.execute_reply": "2023-08-18T19:36:04.130167Z",
-     "shell.execute_reply.started": "2023-08-18T19:36:04.126701Z"
-    },
     "tags": []
    },
    "outputs": [],
@@ -1421,7 +1323,7 @@
    "name": "python",
    "nbconvert_exporter": "python",
    "pygments_lexer": "ipython3",
-   "version": "3.11.4"
+   "version": "3.11.7"
   }
  },
  "nbformat": 4,
diff --git a/polyclonal/__init__.py b/polyclonal/__init__.py
index b61f2636..5bba4609 100644
--- a/polyclonal/__init__.py
+++ b/polyclonal/__init__.py
@@ -31,7 +31,7 @@
 
 __author__ = "`the Bloom lab <https://research.fhcrc.org/bloom/en.html>`_"
 __email__ = "jbloom@fredhutch.org"
-__version__ = "6.9"
+__version__ = "6.10"
 __url__ = "https://github.com/jbloomlab/polyclonal"
 
 from polyclonal.alphabets import AAS
diff --git a/polyclonal/pdb_utils.py b/polyclonal/pdb_utils.py
index 8166dd80..c80f7317 100644
--- a/polyclonal/pdb_utils.py
+++ b/polyclonal/pdb_utils.py
@@ -7,7 +7,6 @@
 
 """
 
-
 import collections  # noqa: F401
 import itertools
 import os  # noqa: F401
diff --git a/polyclonal/plot.py b/polyclonal/plot.py
index 568bc703..5f2b3bd9 100644
--- a/polyclonal/plot.py
+++ b/polyclonal/plot.py
@@ -7,7 +7,6 @@
 
 """
 
-
 import functools
 import math
 import operator
@@ -515,8 +514,10 @@ def lineplot_and_heatmap(
         indicated in the slider.
     addtl_slider_stats_hide_not_filter : None or list
         By default, `addtl_slider_stats` are filtered entirely from data set. If you just
-        them excluded from lineplot calculation but marked as filtered on heat map,
-        add names of stats to this list.
+        them excluded from lineplot but marked as hidden on heat map (eg, gray box),
+        add names of stats to this list. Mutations that fail one of these hiding filters
+        are always shown as hidden on the heat map rather than fully excluded, even if
+        they fail other filters in `addtl_slider_stats`.
     init_floor_at_zero : bool
         Initial value for option to put floor of zero on value is `stat_col`.
     init_site_statistic : {'sum', 'mean', 'max', 'min'}
@@ -657,7 +658,6 @@ def replace_std(col):
         .assign(**{stat_col: lambda x: x[stat_col] * scale_stat_col})
     )
 
-    # filter `data_df` by any minimums in `slider_binding_range_kwargs`
     if slider_binding_range_kwargs is None:
         slider_binding_range_kwargs = {}
 
@@ -723,9 +723,11 @@ def replace_std(col):
     # get tooltips for heatmap
     float_cols = [c for c in req_cols if data_df[c].dtype == float]
     heatmap_tooltips = [
-        alt.Tooltip(c, type="quantitative", format=".3g")
-        if c in float_cols
-        else alt.Tooltip(c, type="nominal")
+        (
+            alt.Tooltip(c, type="quantitative", format=".3g")
+            if c in float_cols
+            else alt.Tooltip(c, type="nominal")
+        )
         for c in req_cols
         if c != category_col or show_category_label
     ]
@@ -954,11 +956,13 @@ def replace_std(col):
                 base_chart = base_chart.transform_filter(
                     (alt.datum[slider_stat] <= (slider + 1e-6))  # round tol
                     | ~alt.expr.isFinite(alt.datum[slider_stat])  # do not filter null
+                    | alt.datum["_stat_hide"]  # do not filter hidden sites
                 )
             else:
                 base_chart = base_chart.transform_filter(
                     (alt.datum[slider_stat] >= (slider - 1e-6))  # round tol
                     | ~alt.expr.isFinite(alt.datum[slider_stat])  # do not filter null
+                    | alt.datum["_stat_hide"]  # do not filter hidden sites
                 )
     # Remove any sites that are only wildtype and filter with site zoom brush
     base_chart = (
@@ -1165,9 +1169,9 @@ def replace_std(col):
         heatmaps.append(heatmap_bg + heatmap_hide + heatmap + heatmap_wildtype)
     heatmaps = alt.vconcat(*heatmaps, spacing=10).resolve_scale(
         x="shared",
-        color="shared"
-        if heatmap_color_scheme or len(categories) == 1
-        else "independent",
+        color=(
+            "shared" if heatmap_color_scheme or len(categories) == 1 else "independent"
+        ),
     )
 
     chartlist = []
diff --git a/polyclonal/polyclonal.py b/polyclonal/polyclonal.py
index 604bc51a..3b137aa3 100644
--- a/polyclonal/polyclonal.py
+++ b/polyclonal/polyclonal.py
@@ -7,7 +7,6 @@
 
 """
 
-
 import collections
 import copy  # noqa: F401
 import inspect
@@ -387,16 +386,16 @@ class Polyclonal:
        barcode aa_substitutions   IC50
     0       AA                   0.085
     1       AC              M1C  0.230
-    2       GA              M1C  0.230
-    3       AG              G2A  0.296
-    4       AT              A4K  0.128
-    5       TA              A4L  0.117
-    6       CA          M1C G2A  0.355
-    7       CG          M1C A4K  0.722
-    8       CC          G2A A4K  1.414
-    9       TC          G2A A4L  0.858
-    10      CT      M1C G2A A4K  3.237
-    11      TG      M1C G2A A4L  1.430
+    2       AG              G2A  0.296
+    3       AT              A4K  0.128
+    4       TA              A4L  0.117
+    5       CA          M1C G2A  0.355
+    6       CG          M1C A4K  0.722
+    7       CC          G2A A4K  1.414
+    8       TC          G2A A4L  0.858
+    9       CT      M1C G2A A4K  3.237
+    10      TG      M1C G2A A4L  1.430
+    11      GA              M1C  0.230
 
     Or the IC90s:
 
@@ -404,16 +403,16 @@ class Polyclonal:
        barcode aa_substitutions    IC90
     0       AA                    0.464
     1       AC              M1C   1.260
-    2       GA              M1C   1.260
-    3       AG              G2A   1.831
-    4       AT              A4K   0.976
-    5       TA              A4L   0.782
-    6       CA          M1C G2A   2.853
-    7       CG          M1C A4K   4.176
-    8       CC          G2A A4K   7.473
-    9       TC          G2A A4L   4.532
-    10      CT      M1C G2A A4K  18.717
-    11      TG      M1C G2A A4L   9.532
+    2       AG              G2A   1.831
+    3       AT              A4K   0.976
+    4       TA              A4L   0.782
+    5       CA          M1C G2A   2.853
+    6       CG          M1C A4K   4.176
+    7       CC          G2A A4K   7.473
+    8       TC          G2A A4L   4.532
+    9       CT      M1C G2A A4K  18.717
+    10      TG      M1C G2A A4L   9.532
+    11      GA              M1C   1.260
 
     Or the fold change IC90s of all mutations:
     >>> model.mut_icXX_df(
@@ -2127,10 +2126,9 @@ def fit(
             fit_kwargs["fix_hill_coefficient"] = True
             fit_kwargs["fix_non_neutralized_frac"] = True
             fit_kwargs["reg_activity_weight"] = fit_fixed_first_reg_activity_weight
-            fit_kwargs[
-                "log_desc"
-            ] = "fixed Hill coefficient and non-neutralized frac" + (
-                f" {log_desc}" if log_desc else ""
+            fit_kwargs["log_desc"] = (
+                "fixed Hill coefficient and non-neutralized frac"
+                + (f" {log_desc}" if log_desc else "")
             )
             self.fit(**fit_kwargs)
         elif fit_site_level_first:
diff --git a/polyclonal/utils.py b/polyclonal/utils.py
index f3071db5..06b0cf15 100644
--- a/polyclonal/utils.py
+++ b/polyclonal/utils.py
@@ -7,7 +7,6 @@
 
 """
 
-
 import re
 
 import pandas as pd  # noqa: F401
diff --git a/setup.py b/setup.py
index 8d7f808c..8ddf1fbb 100644
--- a/setup.py
+++ b/setup.py
@@ -1,6 +1,5 @@
 """Setup script for ``polyclonal``."""
 
-
 import re
 import sys
 
@@ -52,6 +51,7 @@
         "natsort>=8.0",
         "numpy>=1.17",
         "pandas>=1.5",
+        "pyarrow",
         "requests",
         "scipy>=1.7.1",
         "urllib3==1.26.15",  # https://github.com/googleapis/python-bigquery/issues/1565
diff --git a/tests/test_polyclonalaverage.ipynb b/tests/test_polyclonalaverage.ipynb
index 2dd78e3c..e574dd51 100644
--- a/tests/test_polyclonalaverage.ipynb
+++ b/tests/test_polyclonalaverage.ipynb
@@ -22,13 +22,6 @@
    "execution_count": 1,
    "id": "5935c6e6-a5ae-4d73-8f80-03c7d36775f0",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:12.123716Z",
-     "iopub.status.busy": "2023-07-19T19:40:12.123318Z",
-     "iopub.status.idle": "2023-07-19T19:40:14.431939Z",
-     "shell.execute_reply": "2023-07-19T19:40:14.430678Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:12.123687Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -189,13 +182,6 @@
    "execution_count": 2,
    "id": "0667e765-d0d7-40fc-b21b-c2da5fedec23",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:14.441393Z",
-     "iopub.status.busy": "2023-07-19T19:40:14.440939Z",
-     "iopub.status.idle": "2023-07-19T19:40:14.705332Z",
-     "shell.execute_reply": "2023-07-19T19:40:14.704549Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:14.441368Z"
-    },
     "tags": []
    },
    "outputs": [],
@@ -216,13 +202,6 @@
    "execution_count": 3,
    "id": "c6396f53-82f2-4fcf-bd2d-b6f0c03f8d7f",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:14.709597Z",
-     "iopub.status.busy": "2023-07-19T19:40:14.709229Z",
-     "iopub.status.idle": "2023-07-19T19:40:14.819708Z",
-     "shell.execute_reply": "2023-07-19T19:40:14.819088Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:14.709561Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -269,83 +248,83 @@
        "    </tr>\n",
        "    <tr>\n",
        "      <th>1</th>\n",
-       "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.877</td>\n",
        "      <td>A</td>\n",
-       "      <td>0</td>\n",
+       "      <td>1</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.770</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>2</th>\n",
        "      <td>1</td>\n",
-       "      <td>0.877</td>\n",
+       "      <td>0.997</td>\n",
        "      <td>A</td>\n",
-       "      <td>1</td>\n",
+       "      <td>2</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.770</td>\n",
+       "      <td>0.994</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>3</th>\n",
-       "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
-       "      <td>A</td>\n",
        "      <td>1</td>\n",
+       "      <td>0.999</td>\n",
+       "      <td>B</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.999</td>\n",
+       "      <td>0.998</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>4</th>\n",
        "      <td>1</td>\n",
-       "      <td>0.997</td>\n",
-       "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0.893</td>\n",
+       "      <td>B</td>\n",
+       "      <td>1</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.994</td>\n",
+       "      <td>0.798</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>5</th>\n",
        "      <td>2</td>\n",
-       "      <td>0.992</td>\n",
+       "      <td>1.000</td>\n",
        "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.984</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>6</th>\n",
+       "      <td>2</td>\n",
+       "      <td>1.000</td>\n",
+       "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.999</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.998</td>\n",
+       "      <td>0.999</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>7</th>\n",
        "      <td>2</td>\n",
        "      <td>0.992</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
+       "      <td>A</td>\n",
+       "      <td>2</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
        "      <td>0.984</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>8</th>\n",
-       "      <td>1</td>\n",
-       "      <td>0.893</td>\n",
+       "      <td>2</td>\n",
+       "      <td>0.992</td>\n",
        "      <td>B</td>\n",
-       "      <td>1</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.798</td>\n",
+       "      <td>0.984</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>9</th>\n",
@@ -369,83 +348,83 @@
        "    </tr>\n",
        "    <tr>\n",
        "      <th>11</th>\n",
-       "      <td>2</td>\n",
+       "      <td>1</td>\n",
        "      <td>1.000</td>\n",
        "      <td>A</td>\n",
-       "      <td>0</td>\n",
+       "      <td>1</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.999</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>12</th>\n",
        "      <td>1</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.929</td>\n",
        "      <td>A</td>\n",
-       "      <td>1</td>\n",
+       "      <td>2</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.863</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>13</th>\n",
-       "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
-       "      <td>A</td>\n",
        "      <td>1</td>\n",
+       "      <td>-0.289</td>\n",
+       "      <td>B</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.084</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>14</th>\n",
        "      <td>1</td>\n",
-       "      <td>0.929</td>\n",
-       "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0.998</td>\n",
+       "      <td>B</td>\n",
+       "      <td>1</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.863</td>\n",
+       "      <td>0.996</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>15</th>\n",
        "      <td>2</td>\n",
-       "      <td>0.999</td>\n",
+       "      <td>1.000</td>\n",
        "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.998</td>\n",
+       "      <td>0.999</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>16</th>\n",
+       "      <td>2</td>\n",
+       "      <td>1.000</td>\n",
+       "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>-0.289</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.084</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>17</th>\n",
        "      <td>2</td>\n",
-       "      <td>0.966</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
+       "      <td>0.999</td>\n",
+       "      <td>A</td>\n",
+       "      <td>2</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.933</td>\n",
+       "      <td>0.998</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>18</th>\n",
-       "      <td>1</td>\n",
-       "      <td>0.998</td>\n",
+       "      <td>2</td>\n",
+       "      <td>0.966</td>\n",
        "      <td>B</td>\n",
-       "      <td>1</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.996</td>\n",
+       "      <td>0.933</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>19</th>\n",
@@ -469,83 +448,83 @@
        "    </tr>\n",
        "    <tr>\n",
        "      <th>21</th>\n",
-       "      <td>2</td>\n",
-       "      <td>0.992</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.929</td>\n",
        "      <td>A</td>\n",
-       "      <td>0</td>\n",
+       "      <td>1</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>0.984</td>\n",
+       "      <td>0.863</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>22</th>\n",
        "      <td>1</td>\n",
-       "      <td>0.929</td>\n",
+       "      <td>1.000</td>\n",
        "      <td>A</td>\n",
-       "      <td>1</td>\n",
+       "      <td>2</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>0.863</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>23</th>\n",
-       "      <td>2</td>\n",
-       "      <td>0.999</td>\n",
-       "      <td>A</td>\n",
        "      <td>1</td>\n",
+       "      <td>0.993</td>\n",
+       "      <td>B</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>0.998</td>\n",
+       "      <td>0.986</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>24</th>\n",
        "      <td>1</td>\n",
-       "      <td>1.000</td>\n",
-       "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0.941</td>\n",
+       "      <td>B</td>\n",
+       "      <td>1</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.886</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>25</th>\n",
        "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.992</td>\n",
        "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.984</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>26</th>\n",
+       "      <td>2</td>\n",
+       "      <td>0.999</td>\n",
+       "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.993</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>0.986</td>\n",
+       "      <td>0.998</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>27</th>\n",
        "      <td>2</td>\n",
-       "      <td>0.998</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
+       "      <td>1.000</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>0.995</td>\n",
+       "      <td>A</td>\n",
+       "      <td>2</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>28</th>\n",
-       "      <td>1</td>\n",
-       "      <td>0.941</td>\n",
+       "      <td>2</td>\n",
+       "      <td>0.998</td>\n",
        "      <td>B</td>\n",
-       "      <td>1</td>\n",
+       "      <td>0</td>\n",
        "      <td>A</td>\n",
        "      <td>2</td>\n",
-       "      <td>0.886</td>\n",
+       "      <td>0.995</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>29</th>\n",
@@ -569,83 +548,83 @@
        "    </tr>\n",
        "    <tr>\n",
        "      <th>31</th>\n",
-       "      <td>2</td>\n",
-       "      <td>0.992</td>\n",
+       "      <td>1</td>\n",
+       "      <td>-0.289</td>\n",
        "      <td>A</td>\n",
-       "      <td>0</td>\n",
+       "      <td>1</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.984</td>\n",
+       "      <td>0.084</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>32</th>\n",
        "      <td>1</td>\n",
-       "      <td>-0.289</td>\n",
+       "      <td>0.993</td>\n",
        "      <td>A</td>\n",
-       "      <td>1</td>\n",
+       "      <td>2</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.084</td>\n",
+       "      <td>0.986</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>33</th>\n",
-       "      <td>2</td>\n",
-       "      <td>0.966</td>\n",
-       "      <td>A</td>\n",
        "      <td>1</td>\n",
+       "      <td>1.000</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.933</td>\n",
+       "      <td>B</td>\n",
+       "      <td>0</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>34</th>\n",
        "      <td>1</td>\n",
-       "      <td>0.993</td>\n",
-       "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>-0.088</td>\n",
+       "      <td>B</td>\n",
+       "      <td>1</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.986</td>\n",
+       "      <td>0.008</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>35</th>\n",
        "      <td>2</td>\n",
-       "      <td>0.998</td>\n",
+       "      <td>0.992</td>\n",
        "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.995</td>\n",
+       "      <td>0.984</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>36</th>\n",
+       "      <td>2</td>\n",
+       "      <td>0.966</td>\n",
+       "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>1.000</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.933</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>37</th>\n",
        "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
+       "      <td>0.998</td>\n",
+       "      <td>A</td>\n",
+       "      <td>2</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.995</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>38</th>\n",
-       "      <td>1</td>\n",
-       "      <td>-0.088</td>\n",
+       "      <td>2</td>\n",
+       "      <td>1.000</td>\n",
        "      <td>B</td>\n",
-       "      <td>1</td>\n",
+       "      <td>0</td>\n",
        "      <td>B</td>\n",
        "      <td>0</td>\n",
-       "      <td>0.008</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>39</th>\n",
@@ -669,80 +648,80 @@
        "    </tr>\n",
        "    <tr>\n",
        "      <th>41</th>\n",
-       "      <td>2</td>\n",
-       "      <td>0.988</td>\n",
+       "      <td>1</td>\n",
+       "      <td>0.998</td>\n",
        "      <td>A</td>\n",
-       "      <td>0</td>\n",
+       "      <td>1</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.976</td>\n",
+       "      <td>0.996</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>42</th>\n",
        "      <td>1</td>\n",
-       "      <td>0.998</td>\n",
+       "      <td>0.941</td>\n",
        "      <td>A</td>\n",
-       "      <td>1</td>\n",
+       "      <td>2</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.996</td>\n",
+       "      <td>0.886</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>43</th>\n",
-       "      <td>2</td>\n",
-       "      <td>0.991</td>\n",
-       "      <td>A</td>\n",
        "      <td>1</td>\n",
+       "      <td>-0.088</td>\n",
+       "      <td>B</td>\n",
+       "      <td>0</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.981</td>\n",
+       "      <td>0.008</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>44</th>\n",
        "      <td>1</td>\n",
-       "      <td>0.941</td>\n",
-       "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>1.000</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.886</td>\n",
+       "      <td>B</td>\n",
+       "      <td>1</td>\n",
+       "      <td>1.000</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>45</th>\n",
        "      <td>2</td>\n",
-       "      <td>0.996</td>\n",
+       "      <td>0.988</td>\n",
        "      <td>A</td>\n",
-       "      <td>2</td>\n",
+       "      <td>0</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.993</td>\n",
+       "      <td>0.976</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>46</th>\n",
+       "      <td>2</td>\n",
+       "      <td>0.991</td>\n",
+       "      <td>A</td>\n",
        "      <td>1</td>\n",
-       "      <td>-0.088</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
-       "      <td>0.008</td>\n",
+       "      <td>0.981</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>47</th>\n",
        "      <td>2</td>\n",
-       "      <td>1.000</td>\n",
-       "      <td>B</td>\n",
-       "      <td>0</td>\n",
+       "      <td>0.996</td>\n",
+       "      <td>A</td>\n",
+       "      <td>2</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
-       "      <td>1.000</td>\n",
+       "      <td>0.993</td>\n",
        "    </tr>\n",
        "    <tr>\n",
        "      <th>48</th>\n",
-       "      <td>1</td>\n",
+       "      <td>2</td>\n",
        "      <td>1.000</td>\n",
        "      <td>B</td>\n",
-       "      <td>1</td>\n",
+       "      <td>0</td>\n",
        "      <td>B</td>\n",
        "      <td>1</td>\n",
        "      <td>1.000</td>\n",
@@ -764,54 +743,54 @@
       "text/plain": [
        "   epitope  correlation library_1  replicate_1 library_2  replicate_2     r2\n",
        "0        1        1.000         A            0         A            0  1.000\n",
-       "1        2        1.000         A            0         A            0  1.000\n",
-       "2        1        0.877         A            1         A            0  0.770\n",
-       "3        2        1.000         A            1         A            0  0.999\n",
-       "4        1        0.997         A            2         A            0  0.994\n",
-       "5        2        0.992         A            2         A            0  0.984\n",
-       "6        1        0.999         B            0         A            0  0.998\n",
-       "7        2        0.992         B            0         A            0  0.984\n",
-       "8        1        0.893         B            1         A            0  0.798\n",
+       "1        1        0.877         A            1         A            0  0.770\n",
+       "2        1        0.997         A            2         A            0  0.994\n",
+       "3        1        0.999         B            0         A            0  0.998\n",
+       "4        1        0.893         B            1         A            0  0.798\n",
+       "5        2        1.000         A            0         A            0  1.000\n",
+       "6        2        1.000         A            1         A            0  0.999\n",
+       "7        2        0.992         A            2         A            0  0.984\n",
+       "8        2        0.992         B            0         A            0  0.984\n",
        "9        2        0.988         B            1         A            0  0.976\n",
        "10       1        0.877         A            0         A            1  0.770\n",
-       "11       2        1.000         A            0         A            1  0.999\n",
-       "12       1        1.000         A            1         A            1  1.000\n",
-       "13       2        1.000         A            1         A            1  1.000\n",
-       "14       1        0.929         A            2         A            1  0.863\n",
-       "15       2        0.999         A            2         A            1  0.998\n",
-       "16       1       -0.289         B            0         A            1  0.084\n",
-       "17       2        0.966         B            0         A            1  0.933\n",
-       "18       1        0.998         B            1         A            1  0.996\n",
+       "11       1        1.000         A            1         A            1  1.000\n",
+       "12       1        0.929         A            2         A            1  0.863\n",
+       "13       1       -0.289         B            0         A            1  0.084\n",
+       "14       1        0.998         B            1         A            1  0.996\n",
+       "15       2        1.000         A            0         A            1  0.999\n",
+       "16       2        1.000         A            1         A            1  1.000\n",
+       "17       2        0.999         A            2         A            1  0.998\n",
+       "18       2        0.966         B            0         A            1  0.933\n",
        "19       2        0.991         B            1         A            1  0.981\n",
        "20       1        0.997         A            0         A            2  0.994\n",
-       "21       2        0.992         A            0         A            2  0.984\n",
-       "22       1        0.929         A            1         A            2  0.863\n",
-       "23       2        0.999         A            1         A            2  0.998\n",
-       "24       1        1.000         A            2         A            2  1.000\n",
-       "25       2        1.000         A            2         A            2  1.000\n",
-       "26       1        0.993         B            0         A            2  0.986\n",
-       "27       2        0.998         B            0         A            2  0.995\n",
-       "28       1        0.941         B            1         A            2  0.886\n",
+       "21       1        0.929         A            1         A            2  0.863\n",
+       "22       1        1.000         A            2         A            2  1.000\n",
+       "23       1        0.993         B            0         A            2  0.986\n",
+       "24       1        0.941         B            1         A            2  0.886\n",
+       "25       2        0.992         A            0         A            2  0.984\n",
+       "26       2        0.999         A            1         A            2  0.998\n",
+       "27       2        1.000         A            2         A            2  1.000\n",
+       "28       2        0.998         B            0         A            2  0.995\n",
        "29       2        0.996         B            1         A            2  0.993\n",
        "30       1        0.999         A            0         B            0  0.998\n",
-       "31       2        0.992         A            0         B            0  0.984\n",
-       "32       1       -0.289         A            1         B            0  0.084\n",
-       "33       2        0.966         A            1         B            0  0.933\n",
-       "34       1        0.993         A            2         B            0  0.986\n",
-       "35       2        0.998         A            2         B            0  0.995\n",
-       "36       1        1.000         B            0         B            0  1.000\n",
-       "37       2        1.000         B            0         B            0  1.000\n",
-       "38       1       -0.088         B            1         B            0  0.008\n",
+       "31       1       -0.289         A            1         B            0  0.084\n",
+       "32       1        0.993         A            2         B            0  0.986\n",
+       "33       1        1.000         B            0         B            0  1.000\n",
+       "34       1       -0.088         B            1         B            0  0.008\n",
+       "35       2        0.992         A            0         B            0  0.984\n",
+       "36       2        0.966         A            1         B            0  0.933\n",
+       "37       2        0.998         A            2         B            0  0.995\n",
+       "38       2        1.000         B            0         B            0  1.000\n",
        "39       2        1.000         B            1         B            0  1.000\n",
        "40       1        0.893         A            0         B            1  0.798\n",
-       "41       2        0.988         A            0         B            1  0.976\n",
-       "42       1        0.998         A            1         B            1  0.996\n",
-       "43       2        0.991         A            1         B            1  0.981\n",
-       "44       1        0.941         A            2         B            1  0.886\n",
-       "45       2        0.996         A            2         B            1  0.993\n",
-       "46       1       -0.088         B            0         B            1  0.008\n",
-       "47       2        1.000         B            0         B            1  1.000\n",
-       "48       1        1.000         B            1         B            1  1.000\n",
+       "41       1        0.998         A            1         B            1  0.996\n",
+       "42       1        0.941         A            2         B            1  0.886\n",
+       "43       1       -0.088         B            0         B            1  0.008\n",
+       "44       1        1.000         B            1         B            1  1.000\n",
+       "45       2        0.988         A            0         B            1  0.976\n",
+       "46       2        0.991         A            1         B            1  0.981\n",
+       "47       2        0.996         A            2         B            1  0.993\n",
+       "48       2        1.000         B            0         B            1  1.000\n",
        "49       2        1.000         B            1         B            1  1.000"
       ]
      },
@@ -847,13 +826,6 @@
    "execution_count": 4,
    "id": "fa1cdd44-0748-4a57-b56d-1d0cfc6ba073",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:14.822592Z",
-     "iopub.status.busy": "2023-07-19T19:40:14.822361Z",
-     "iopub.status.idle": "2023-07-19T19:40:14.992389Z",
-     "shell.execute_reply": "2023-07-19T19:40:14.991187Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:14.822572Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -862,28 +834,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-f2d873547c6f44938345a5b41a2799c7.vega-embed {\n",
+       "  #altair-viz-f820b11fb3c04122bb7635ae1404472e.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-f2d873547c6f44938345a5b41a2799c7.vega-embed details,\n",
-       "  #altair-viz-f2d873547c6f44938345a5b41a2799c7.vega-embed details summary {\n",
+       "  #altair-viz-f820b11fb3c04122bb7635ae1404472e.vega-embed details,\n",
+       "  #altair-viz-f820b11fb3c04122bb7635ae1404472e.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-f2d873547c6f44938345a5b41a2799c7\"></div>\n",
+       "<div id=\"altair-viz-f820b11fb3c04122bb7635ae1404472e\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-f2d873547c6f44938345a5b41a2799c7\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-f2d873547c6f44938345a5b41a2799c7\");\n",
+       "    if (outputDiv.id !== \"altair-viz-f820b11fb3c04122bb7635ae1404472e\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-f820b11fb3c04122bb7635ae1404472e\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -919,12 +891,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"labelLimit\": 500}}, \"data\": {\"name\": \"data-f28ad4c00b1c74baea882b1e907bb7ee\"}, \"mark\": {\"type\": \"rect\", \"stroke\": \"black\"}, \"encoding\": {\"color\": {\"field\": \"r2\", \"scale\": {\"domain\": [0, 1], \"scheme\": \"yellowgreenblue\"}, \"type\": \"quantitative\"}, \"facet\": {\"columns\": 3, \"field\": \"epitope\", \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"r\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"r2\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"library_1\", \"type\": \"nominal\"}, {\"field\": \"replicate_1\", \"type\": \"quantitative\"}, {\"field\": \"library_2\", \"type\": \"nominal\"}, {\"field\": \"replicate_2\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_label_1\", \"title\": null, \"type\": \"nominal\"}, \"y\": {\"field\": \"_label_2\", \"title\": null, \"type\": \"nominal\"}}, \"height\": {\"step\": 15}, \"width\": {\"step\": 15}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-f28ad4c00b1c74baea882b1e907bb7ee\": [{\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}, {\"r\": 0.8773798123199854, \"r2\": 0.7697953350666528, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"A-0\"}, {\"r\": 0.9996962573276795, \"r2\": 0.99939260691497, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"A-0\"}, {\"r\": 0.9971295415789166, \"r2\": 0.9942673226893805, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"A-0\"}, {\"r\": 0.9921010175738242, \"r2\": 0.9842644290710174, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"A-0\"}, {\"r\": 0.9991858761797873, \"r2\": 0.9983724151571691, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"A-0\"}, {\"r\": 0.9917580348440374, \"r2\": 0.9835839996777068, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"A-0\"}, {\"r\": 0.8934312791152936, \"r2\": 0.7982194505015897, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"A-0\"}, {\"r\": 0.9877468639344096, \"r2\": 0.975643867212261, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"A-0\"}, {\"r\": 0.8773798123199854, \"r2\": 0.7697953350666528, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"A-1\"}, {\"r\": 0.9996962573276795, \"r2\": 0.99939260691497, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"A-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"A-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"A-1\"}, {\"r\": 0.92919195563458, \"r2\": 0.8633976904160153, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"A-1\"}, {\"r\": 0.998937533707095, \"r2\": 0.9978761962488136, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"A-1\"}, {\"r\": -0.28905012331204355, \"r2\": 0.08354997378670759, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"A-1\"}, {\"r\": 0.9660388215724064, \"r2\": 0.9332310047850036, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"A-1\"}, {\"r\": 0.997789750783417, \"r2\": 0.9955843867684334, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"A-1\"}, {\"r\": 0.9906131641014112, \"r2\": 0.9813144408910094, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"A-1\"}, {\"r\": 0.9971295415789166, \"r2\": 0.9942673226893805, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.9921010175738242, \"r2\": 0.9842644290710174, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.92919195563458, \"r2\": 0.8633976904160153, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-1\", \"_label_2\": \"A-2\"}, {\"r\": 0.998937533707095, \"r2\": 0.9978761962488136, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-1\", \"_label_2\": \"A-2\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-2\", \"_label_2\": \"A-2\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-2\", \"_label_2\": \"A-2\"}, {\"r\": 0.9930101106948575, \"r2\": 0.986069079942213, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.9975330574338195, \"r2\": 0.9950722006732637, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.94140553269588, \"r2\": 0.8862443769904136, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-1\", \"_label_2\": \"A-2\"}, {\"r\": 0.9963080426772687, \"r2\": 0.9926297159034102, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-1\", \"_label_2\": \"A-2\"}, {\"r\": 0.9991858761797873, \"r2\": 0.9983724151571691, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"B-0\"}, {\"r\": 0.9917580348440374, \"r2\": 0.9835839996777068, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"B-0\"}, {\"r\": -0.28905012331204355, \"r2\": 0.08354997378670759, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.9660388215724064, \"r2\": 0.9332310047850036, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.9930101106948575, \"r2\": 0.986069079942213, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"B-0\"}, {\"r\": 0.9975330574338195, \"r2\": 0.9950722006732637, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"B-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"B-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"B-0\"}, {\"r\": -0.08776845509107678, \"r2\": 0.007703301709074362, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.9997810743031644, \"r2\": 0.9995621965347896, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.8934312791152936, \"r2\": 0.7982194505015897, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"B-1\"}, {\"r\": 0.9877468639344096, \"r2\": 0.975643867212261, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"B-1\"}, {\"r\": 0.997789750783417, \"r2\": 0.9955843867684334, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"B-1\"}, {\"r\": 0.9906131641014112, \"r2\": 0.9813144408910094, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"B-1\"}, {\"r\": 0.94140553269588, \"r2\": 0.8862443769904136, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"B-1\"}, {\"r\": 0.9963080426772687, \"r2\": 0.9926297159034102, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"B-1\"}, {\"r\": -0.08776845509107678, \"r2\": 0.007703301709074362, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"B-1\"}, {\"r\": 0.9997810743031644, \"r2\": 0.9995621965347896, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"B-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"B-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"B-1\"}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"labelLimit\": 500}}, \"data\": {\"name\": \"data-cf4f728c40a4062d3357ad0ffc3bfce9\"}, \"mark\": {\"type\": \"rect\", \"stroke\": \"black\"}, \"encoding\": {\"color\": {\"field\": \"r2\", \"scale\": {\"domain\": [0, 1], \"scheme\": \"yellowgreenblue\"}, \"type\": \"quantitative\"}, \"facet\": {\"columns\": 3, \"field\": \"epitope\", \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"r\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"r2\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"library_1\", \"type\": \"nominal\"}, {\"field\": \"replicate_1\", \"type\": \"quantitative\"}, {\"field\": \"library_2\", \"type\": \"nominal\"}, {\"field\": \"replicate_2\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_label_1\", \"title\": null, \"type\": \"nominal\"}, \"y\": {\"field\": \"_label_2\", \"title\": null, \"type\": \"nominal\"}}, \"height\": {\"step\": 15}, \"width\": {\"step\": 15}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-cf4f728c40a4062d3357ad0ffc3bfce9\": [{\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}, {\"r\": 0.8773798123199854, \"r2\": 0.7697953350666528, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"A-0\"}, {\"r\": 0.9971295415789166, \"r2\": 0.9942673226893805, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"A-0\"}, {\"r\": 0.9991858761797873, \"r2\": 0.9983724151571691, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"A-0\"}, {\"r\": 0.8934312791152936, \"r2\": 0.7982194505015897, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"A-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}, {\"r\": 0.9996962573276795, \"r2\": 0.99939260691497, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"A-0\"}, {\"r\": 0.9921010175738242, \"r2\": 0.9842644290710174, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"A-0\"}, {\"r\": 0.9917580348440374, \"r2\": 0.9835839996777068, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"A-0\"}, {\"r\": 0.9877468639344096, \"r2\": 0.975643867212261, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"A-0\"}, {\"r\": 0.8773798123199854, \"r2\": 0.7697953350666528, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"A-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"A-1\"}, {\"r\": 0.92919195563458, \"r2\": 0.8633976904160153, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"A-1\"}, {\"r\": -0.28905012331204355, \"r2\": 0.08354997378670759, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"A-1\"}, {\"r\": 0.997789750783417, \"r2\": 0.9955843867684334, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"A-1\"}, {\"r\": 0.9996962573276795, \"r2\": 0.99939260691497, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"A-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"A-1\"}, {\"r\": 0.998937533707095, \"r2\": 0.9978761962488136, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"A-1\"}, {\"r\": 0.9660388215724064, \"r2\": 0.9332310047850036, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"A-1\"}, {\"r\": 0.9906131641014112, \"r2\": 0.9813144408910094, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"A-1\"}, {\"r\": 0.9971295415789166, \"r2\": 0.9942673226893805, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.92919195563458, \"r2\": 0.8633976904160153, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-1\", \"_label_2\": \"A-2\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-2\", \"_label_2\": \"A-2\"}, {\"r\": 0.9930101106948575, \"r2\": 0.986069079942213, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.94140553269588, \"r2\": 0.8862443769904136, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-1\", \"_label_2\": \"A-2\"}, {\"r\": 0.9921010175738242, \"r2\": 0.9842644290710174, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.998937533707095, \"r2\": 0.9978761962488136, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-1\", \"_label_2\": \"A-2\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"A-2\", \"_label_2\": \"A-2\"}, {\"r\": 0.9975330574338195, \"r2\": 0.9950722006732637, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-0\", \"_label_2\": \"A-2\"}, {\"r\": 0.9963080426772687, \"r2\": 0.9926297159034102, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"A\", \"replicate_2\": 2, \"_label_1\": \"B-1\", \"_label_2\": \"A-2\"}, {\"r\": 0.9991858761797873, \"r2\": 0.9983724151571691, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"B-0\"}, {\"r\": -0.28905012331204355, \"r2\": 0.08354997378670759, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.9930101106948575, \"r2\": 0.986069079942213, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"B-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"B-0\"}, {\"r\": -0.08776845509107678, \"r2\": 0.007703301709074362, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.9917580348440374, \"r2\": 0.9835839996777068, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"B-0\"}, {\"r\": 0.9660388215724064, \"r2\": 0.9332310047850036, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.9975330574338195, \"r2\": 0.9950722006732637, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"A-2\", \"_label_2\": \"B-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-0\", \"_label_2\": \"B-0\"}, {\"r\": 0.9997810743031644, \"r2\": 0.9995621965347896, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 0, \"_label_1\": \"B-1\", \"_label_2\": \"B-0\"}, {\"r\": 0.8934312791152936, \"r2\": 0.7982194505015897, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"B-1\"}, {\"r\": 0.997789750783417, \"r2\": 0.9955843867684334, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"B-1\"}, {\"r\": 0.94140553269588, \"r2\": 0.8862443769904136, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"B-1\"}, {\"r\": -0.08776845509107678, \"r2\": 0.007703301709074362, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"B-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"B-1\"}, {\"r\": 0.9877468639344096, \"r2\": 0.975643867212261, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-0\", \"_label_2\": \"B-1\"}, {\"r\": 0.9906131641014112, \"r2\": 0.9813144408910094, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-1\", \"_label_2\": \"B-1\"}, {\"r\": 0.9963080426772687, \"r2\": 0.9926297159034102, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 2, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"A-2\", \"_label_2\": \"B-1\"}, {\"r\": 0.9997810743031644, \"r2\": 0.9995621965347896, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 0, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-0\", \"_label_2\": \"B-1\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"B\", \"replicate_1\": 1, \"library_2\": \"B\", \"replicate_2\": 1, \"_label_1\": \"B-1\", \"_label_2\": \"B-1\"}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -955,13 +927,6 @@
    "execution_count": 5,
    "id": "250f75fb-b87c-4e1b-9034-15483d7c7e8d",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:14.997044Z",
-     "iopub.status.busy": "2023-07-19T19:40:14.996664Z",
-     "iopub.status.idle": "2023-07-19T19:40:15.011681Z",
-     "shell.execute_reply": "2023-07-19T19:40:15.010970Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:14.997015Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -1095,13 +1060,6 @@
    "execution_count": 6,
    "id": "7ef29b17-be20-4f68-a794-ef6d646898fe",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:15.014876Z",
-     "iopub.status.busy": "2023-07-19T19:40:15.014631Z",
-     "iopub.status.idle": "2023-07-19T19:40:15.032342Z",
-     "shell.execute_reply": "2023-07-19T19:40:15.031665Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:15.014854Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -1171,13 +1129,6 @@
    "execution_count": 7,
    "id": "2dc2eab2-d846-488d-aa0d-69cc9c0d621f",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:15.035416Z",
-     "iopub.status.busy": "2023-07-19T19:40:15.035163Z",
-     "iopub.status.idle": "2023-07-19T19:40:15.127505Z",
-     "shell.execute_reply": "2023-07-19T19:40:15.126569Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:15.035397Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -1186,28 +1137,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-c91c3188b5a5474187bb0f64c4a3377c.vega-embed {\n",
+       "  #altair-viz-72106f11304d4950aa7282a7d3958a68.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-c91c3188b5a5474187bb0f64c4a3377c.vega-embed details,\n",
-       "  #altair-viz-c91c3188b5a5474187bb0f64c4a3377c.vega-embed details summary {\n",
+       "  #altair-viz-72106f11304d4950aa7282a7d3958a68.vega-embed details,\n",
+       "  #altair-viz-72106f11304d4950aa7282a7d3958a68.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-c91c3188b5a5474187bb0f64c4a3377c\"></div>\n",
+       "<div id=\"altair-viz-72106f11304d4950aa7282a7d3958a68\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-c91c3188b5a5474187bb0f64c4a3377c\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-c91c3188b5a5474187bb0f64c4a3377c\");\n",
+       "    if (outputDiv.id !== \"altair-viz-72106f11304d4950aa7282a7d3958a68\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-72106f11304d4950aa7282a7d3958a68\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -1243,12 +1194,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"layer\": [{\"mark\": {\"type\": \"bar\", \"size\": 18.75}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"1\", \"2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"activity_median\", \"title\": \"activity_median\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}, {\"mark\": {\"type\": \"rule\", \"size\": 2}, \"encoding\": {\"color\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_lower\", \"type\": \"quantitative\"}, \"x2\": {\"field\": \"_upper\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}], \"data\": {\"name\": \"data-ffe21e155a2a18b3ba0f003b58f87b0d\"}, \"height\": {\"step\": 25}, \"width\": 110, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-ffe21e155a2a18b3ba0f003b58f87b0d\": [{\"epitope\": \"1\", \"activity_mean\": 2.583931630472031, \"activity_median\": 2.5488135039273248, \"activity_std\": 0.22295709390357102, \"_lower\": 2.3258564100237535, \"_upper\": 2.771770597830896}, {\"epitope\": \"2\", \"activity_mean\": 1.543364032687259, \"activity_median\": 1.7081478226181048, \"activity_std\": 0.2982236946687655, \"_lower\": 1.4099241279493393, \"_upper\": 2.0063715172868704}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"layer\": [{\"mark\": {\"type\": \"bar\", \"size\": 18.75}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"1\", \"2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"activity_median\", \"title\": \"activity_median\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}, {\"mark\": {\"type\": \"rule\", \"size\": 2}, \"encoding\": {\"color\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_lower\", \"type\": \"quantitative\"}, \"x2\": {\"field\": \"_upper\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}], \"data\": {\"name\": \"data-ffe21e155a2a18b3ba0f003b58f87b0d\"}, \"height\": {\"step\": 25}, \"width\": 110, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-ffe21e155a2a18b3ba0f003b58f87b0d\": [{\"epitope\": \"1\", \"activity_mean\": 2.583931630472031, \"activity_median\": 2.5488135039273248, \"activity_std\": 0.22295709390357102, \"_lower\": 2.3258564100237535, \"_upper\": 2.771770597830896}, {\"epitope\": \"2\", \"activity_mean\": 1.543364032687259, \"activity_median\": 1.7081478226181048, \"activity_std\": 0.2982236946687655, \"_lower\": 1.4099241279493393, \"_upper\": 2.0063715172868704}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -1278,43 +1229,35 @@
    "cell_type": "code",
    "execution_count": 8,
    "id": "5e784d25-67cc-49e7-be35-3689e4c2128d",
-   "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:15.128820Z",
-     "iopub.status.busy": "2023-07-19T19:40:15.128502Z",
-     "iopub.status.idle": "2023-07-19T19:40:15.209162Z",
-     "shell.execute_reply": "2023-07-19T19:40:15.208389Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:15.128799Z"
-    }
-   },
+   "metadata": {},
    "outputs": [
     {
      "data": {
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-df6f46e9dd634495b32a4d9a2d6be910.vega-embed {\n",
+       "  #altair-viz-6d6f703ab8414bcb9bd38206715bf1cf.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-df6f46e9dd634495b32a4d9a2d6be910.vega-embed details,\n",
-       "  #altair-viz-df6f46e9dd634495b32a4d9a2d6be910.vega-embed details summary {\n",
+       "  #altair-viz-6d6f703ab8414bcb9bd38206715bf1cf.vega-embed details,\n",
+       "  #altair-viz-6d6f703ab8414bcb9bd38206715bf1cf.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-df6f46e9dd634495b32a4d9a2d6be910\"></div>\n",
+       "<div id=\"altair-viz-6d6f703ab8414bcb9bd38206715bf1cf\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-df6f46e9dd634495b32a4d9a2d6be910\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-df6f46e9dd634495b32a4d9a2d6be910\");\n",
+       "    if (outputDiv.id !== \"altair-viz-6d6f703ab8414bcb9bd38206715bf1cf\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-6d6f703ab8414bcb9bd38206715bf1cf\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -1350,12 +1293,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"layer\": [{\"mark\": {\"type\": \"bar\", \"size\": 18.75}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"1\", \"2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"activity_mean\", \"title\": \"activity_mean\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}, {\"mark\": {\"type\": \"rule\", \"size\": 2}, \"encoding\": {\"color\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_lower\", \"type\": \"quantitative\"}, \"x2\": {\"field\": \"_upper\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}], \"data\": {\"name\": \"data-e24935b20356632687c18b9f2bdebe0f\"}, \"height\": {\"step\": 25}, \"width\": 110, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-e24935b20356632687c18b9f2bdebe0f\": [{\"epitope\": \"1\", \"activity_mean\": 2.583931630472031, \"activity_median\": 2.5488135039273248, \"activity_std\": 0.22295709390357102, \"_lower\": 2.3609745365684596, \"_upper\": 2.806888724375602}, {\"epitope\": \"2\", \"activity_mean\": 1.543364032687259, \"activity_median\": 1.7081478226181048, \"activity_std\": 0.2982236946687655, \"_lower\": 1.2451403380184936, \"_upper\": 1.8415877273560246}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"layer\": [{\"mark\": {\"type\": \"bar\", \"size\": 18.75}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"1\", \"2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"activity_mean\", \"title\": \"activity_mean\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}, {\"mark\": {\"type\": \"rule\", \"size\": 2}, \"encoding\": {\"color\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_lower\", \"type\": \"quantitative\"}, \"x2\": {\"field\": \"_upper\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}], \"data\": {\"name\": \"data-e24935b20356632687c18b9f2bdebe0f\"}, \"height\": {\"step\": 25}, \"width\": 110, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-e24935b20356632687c18b9f2bdebe0f\": [{\"epitope\": \"1\", \"activity_mean\": 2.583931630472031, \"activity_median\": 2.5488135039273248, \"activity_std\": 0.22295709390357102, \"_lower\": 2.3609745365684596, \"_upper\": 2.806888724375602}, {\"epitope\": \"2\", \"activity_mean\": 1.543364032687259, \"activity_median\": 1.7081478226181048, \"activity_std\": 0.2982236946687655, \"_lower\": 1.2451403380184936, \"_upper\": 1.8415877273560246}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -1386,13 +1329,6 @@
    "execution_count": 9,
    "id": "4520c763-f8da-45cc-9987-bcbb2214f85e",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:15.210452Z",
-     "iopub.status.busy": "2023-07-19T19:40:15.210162Z",
-     "iopub.status.idle": "2023-07-19T19:40:15.371701Z",
-     "shell.execute_reply": "2023-07-19T19:40:15.371100Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:15.210434Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -1930,13 +1866,6 @@
    "execution_count": 10,
    "id": "0e88ba97-d25c-4d5a-a6f2-469bd90d39d7",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:15.373077Z",
-     "iopub.status.busy": "2023-07-19T19:40:15.372746Z",
-     "iopub.status.idle": "2023-07-19T19:40:15.430205Z",
-     "shell.execute_reply": "2023-07-19T19:40:15.429502Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:15.373058Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -2159,13 +2088,6 @@
    "execution_count": 11,
    "id": "52b6b660-a2fc-461d-bf2f-d4aebb624314",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:15.431276Z",
-     "iopub.status.busy": "2023-07-19T19:40:15.431010Z",
-     "iopub.status.idle": "2023-07-19T19:40:16.700983Z",
-     "shell.execute_reply": "2023-07-19T19:40:16.700405Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:15.431258Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -2174,28 +2096,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-e1258ed41f7f41fa86947cc4aa509d7e.vega-embed {\n",
+       "  #altair-viz-0dc7d7638cbd4103a88c30e19371c75d.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-e1258ed41f7f41fa86947cc4aa509d7e.vega-embed details,\n",
-       "  #altair-viz-e1258ed41f7f41fa86947cc4aa509d7e.vega-embed details summary {\n",
+       "  #altair-viz-0dc7d7638cbd4103a88c30e19371c75d.vega-embed details,\n",
+       "  #altair-viz-0dc7d7638cbd4103a88c30e19371c75d.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-e1258ed41f7f41fa86947cc4aa509d7e\"></div>\n",
+       "<div id=\"altair-viz-0dc7d7638cbd4103a88c30e19371c75d\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-e1258ed41f7f41fa86947cc4aa509d7e\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-e1258ed41f7f41fa86947cc4aa509d7e\");\n",
+       "    if (outputDiv.id !== \"altair-viz-0dc7d7638cbd4103a88c30e19371c75d\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-0dc7d7638cbd4103a88c30e19371c75d\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -2231,12 +2153,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-42e7f5dbd0282babbfecc80c452dbb2f\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_2\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_1\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_3\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-0036197f12b0ff1e884b038f70b4f01d\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_3\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}, {\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_4\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#fcf8fa\", \"#faf1f6\", \"#f7eaf1\", \"#f4e3ec\", \"#f2dce8\", \"#efd5e3\", \"#eccedf\", \"#eac7da\", \"#e7c0d5\", \"#e4b8d1\", \"#e1b1cc\", \"#dfaac7\", \"#dca3c3\", \"#d99cbe\", \"#d795ba\", \"#d48eb5\", \"#d187b0\", \"#cf80ac\", \"#cc79a7\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_1['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_2['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_4\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-0036197f12b0ff1e884b038f70b4f01d\"}, \"resolve\": {\"scale\": {\"color\": \"independent\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_4\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_2\", \"view_1\", \"view_3\", \"view_4\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_1\"]}, {\"name\": \"param_3\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_1\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, 0.0], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_2\", \"view_1\", \"view_3\", \"view_4\"]}, {\"name\": \"param_1\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 5.0, \"min\": 3.0, \"name\": \"minimum n_models\"}, \"value\": [{\"cutoff\": 3}], \"views\": [\"view_2\", \"view_1\", \"view_3\", \"view_4\"]}, {\"name\": \"param_2\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 3.7295772137298258, \"min\": 0.0, \"name\": \"minimum max of escape at site\"}, \"value\": [{\"cutoff\": 0.0}], \"views\": [\"view_2\", \"view_1\", \"view_3\", \"view_4\"]}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-42e7f5dbd0282babbfecc80c452dbb2f\": [{\"site\": \"1\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"_stat_site_order\": 2}], \"data-0036197f12b0ff1e884b038f70b4f01d\": [{\"site\": \"1\", \"mutant\": \"C\", \"escape\": 2.4639455131088055, \"epitope\": \"epitope 1\", \"A 0\": 2.6458941130666562, \"A 1\": 2.236088976951976, \"A 2\": 2.3303348210038743, \"B 0\": null, \"B 1\": 2.5975562052137366, \"n_models\": 4.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 3.6192709663506637, \"epitope\": \"epitope 1\", \"A 0\": 3.89177300078208, \"A 1\": null, \"A 2\": 3.6192709663506637, \"B 0\": 3.125585310463836, \"B 1\": null, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 0.3834415188257777, \"epitope\": \"epitope 1\", \"A 0\": 0.3834415188257777, \"A 1\": 0.9355390708060318, \"A 2\": 0.26682727510286663, \"B 0\": 0.05146720330082988, \"B 1\": 0.9031785237401092, \"n_models\": 5.0}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 0.029876210878566956, \"epitope\": \"epitope 1\", \"A 0\": null, \"A 1\": 0.3132735169322751, \"A 2\": null, \"B 0\": 0.029876210878566956, \"B 1\": 0.005159148556627802, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 0.5135781212657464, \"epitope\": \"epitope 1\", \"A 0\": 0.925596638292661, \"A 1\": 0.44345289377955666, \"A 2\": 0.5135781212657464, \"B 0\": 0.6491440476147607, \"B 1\": 0.3614963440850427, \"n_models\": 5.0}, {\"site\": \"1\", \"mutant\": \"C\", \"escape\": 0.3006146806669343, \"epitope\": \"epitope 2\", \"A 0\": 0.4375872112626925, \"A 1\": 0.3965807272960261, \"A 2\": 0.2046486340378425, \"B 0\": null, \"B 1\": 0.14146417361702357, \"n_models\": 4.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 0.29965467367452314, \"epitope\": \"epitope 2\", \"A 0\": 0.9636627605010293, \"A 1\": null, \"A 2\": 0.29965467367452314, \"B 0\": 0.20724287813818676, \"B 1\": null, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 3.132963104392461, \"epitope\": \"epitope 2\", \"A 0\": 3.2917250380826646, \"A 1\": 3.346310916686017, \"A 2\": 3.121133832769295, \"B 0\": 2.9408098436506362, \"B 1\": 3.132963104392461, \"n_models\": 5.0}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 2.0245481595728716, \"epitope\": \"epitope 2\", \"A 0\": null, \"A 1\": 2.0245481595728716, \"A 2\": null, \"B 0\": 1.956833224394711, \"B 1\": 2.07235649126018, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 3.7295772137298258, \"epitope\": \"epitope 2\", \"A 0\": 3.571036058197887, \"A 1\": 3.7295772137298258, \"A 2\": 3.6844398656469153, \"B 0\": 3.7784872826479754, \"B 1\": 4.104131938247697, \"n_models\": 5.0}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}], \"data-a7d600054b448517d77aab4449a3c18a\": [{\"site\": \"1\", \"wildtype\": \"M\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"wildtype\": \"G\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"wildtype\": \"A\", \"_stat_site_order\": 2}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-42e7f5dbd0282babbfecc80c452dbb2f\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_2\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_1\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_4\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-b367b4916fe032dae7f5c728ade839ae\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_3\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}, {\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_4\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#fcf8fa\", \"#faf1f6\", \"#f7eaf1\", \"#f4e3ec\", \"#f2dce8\", \"#efd5e3\", \"#eccedf\", \"#eac7da\", \"#e7c0d5\", \"#e4b8d1\", \"#e1b1cc\", \"#dfaac7\", \"#dca3c3\", \"#d99cbe\", \"#d795ba\", \"#d48eb5\", \"#d187b0\", \"#cf80ac\", \"#cc79a7\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_1 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_2 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_3 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_5\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-b367b4916fe032dae7f5c728ade839ae\"}, \"resolve\": {\"scale\": {\"color\": \"independent\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_5\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_2\", \"view_1\", \"view_3\", \"view_4\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_1\"]}, {\"name\": \"param_4\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_1\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, 0.029876210878566956], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_2\", \"view_1\", \"view_3\", \"view_4\"]}, {\"name\": \"param_1\", \"bind\": {\"input\": \"range\", \"max\": 5.0, \"min\": 3.0, \"name\": \"minimum n_models\"}, \"value\": 3}, {\"name\": \"param_2\", \"bind\": {\"input\": \"range\", \"max\": 0.4126373948474744, \"min\": 0.05804678316119469, \"name\": \"maximum escape_std\"}, \"value\": 0.4126373948474744}, {\"name\": \"param_3\", \"bind\": {\"input\": \"range\", \"max\": 3.7295772137298258, \"min\": 0.029876210878566956, \"name\": \"minimum max of escape at site\"}, \"value\": 0.029876210878566956}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-42e7f5dbd0282babbfecc80c452dbb2f\": [{\"site\": \"1\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"_stat_site_order\": 2}], \"data-b367b4916fe032dae7f5c728ade839ae\": [{\"site\": \"1\", \"mutant\": \"C\", \"escape\": 2.4639455131088055, \"epitope\": \"epitope 1\", \"A 0\": 2.6458941130666562, \"A 1\": 2.236088976951976, \"A 2\": 2.3303348210038743, \"B 0\": null, \"B 1\": 2.5975562052137366, \"n_models\": 4.0, \"escape_std\": 0.2001671331113208}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 3.6192709663506637, \"epitope\": \"epitope 1\", \"A 0\": 3.89177300078208, \"A 1\": null, \"A 2\": 3.6192709663506637, \"B 0\": 3.125585310463836, \"B 1\": null, \"n_models\": 3.0, \"escape_std\": 0.3883783512660632}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 0.3834415188257777, \"epitope\": \"epitope 1\", \"A 0\": 0.3834415188257777, \"A 1\": 0.9355390708060318, \"A 2\": 0.26682727510286663, \"B 0\": 0.05146720330082988, \"B 1\": 0.9031785237401092, \"n_models\": 5.0, \"escape_std\": 0.39403584052427915}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 0.029876210878566956, \"epitope\": \"epitope 1\", \"A 0\": null, \"A 1\": 0.3132735169322751, \"A 2\": null, \"B 0\": 0.029876210878566956, \"B 1\": 0.005159148556627802, \"n_models\": 3.0, \"escape_std\": 0.1712013581760037}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 0.5135781212657464, \"epitope\": \"epitope 1\", \"A 0\": 0.925596638292661, \"A 1\": 0.44345289377955666, \"A 2\": 0.5135781212657464, \"B 0\": 0.6491440476147607, \"B 1\": 0.3614963440850427, \"n_models\": 5.0, \"escape_std\": 0.22079951184059773}, {\"site\": \"1\", \"mutant\": \"C\", \"escape\": 0.3006146806669343, \"epitope\": \"epitope 2\", \"A 0\": 0.4375872112626925, \"A 1\": 0.3965807272960261, \"A 2\": 0.2046486340378425, \"B 0\": null, \"B 1\": 0.14146417361702357, \"n_models\": 4.0, \"escape_std\": 0.14420628347773592}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 0.29965467367452314, \"epitope\": \"epitope 2\", \"A 0\": 0.9636627605010293, \"A 1\": null, \"A 2\": 0.29965467367452314, \"B 0\": 0.20724287813818676, \"B 1\": null, \"n_models\": 3.0, \"escape_std\": 0.4126373948474744}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 3.132963104392461, \"epitope\": \"epitope 2\", \"A 0\": 3.2917250380826646, \"A 1\": 3.346310916686017, \"A 2\": 3.121133832769295, \"B 0\": 2.9408098436506362, \"B 1\": 3.132963104392461, \"n_models\": 5.0, \"escape_std\": 0.15979056283813148}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 2.0245481595728716, \"epitope\": \"epitope 2\", \"A 0\": null, \"A 1\": 2.0245481595728716, \"A 2\": null, \"B 0\": 1.956833224394711, \"B 1\": 2.07235649126018, \"n_models\": 3.0, \"escape_std\": 0.05804678316119469}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 3.7295772137298258, \"epitope\": \"epitope 2\", \"A 0\": 3.571036058197887, \"A 1\": 3.7295772137298258, \"A 2\": 3.6844398656469153, \"B 0\": 3.7784872826479754, \"B 1\": 4.104131938247697, \"n_models\": 5.0, \"escape_std\": 0.2001217829541086}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}], \"data-a7d600054b448517d77aab4449a3c18a\": [{\"site\": \"1\", \"wildtype\": \"M\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"wildtype\": \"G\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"wildtype\": \"A\", \"_stat_site_order\": 2}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -2267,13 +2189,6 @@
    "execution_count": 12,
    "id": "957a1c96-80e2-4880-8c34-0a31eb8166a7",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:16.701913Z",
-     "iopub.status.busy": "2023-07-19T19:40:16.701722Z",
-     "iopub.status.idle": "2023-07-19T19:40:16.774220Z",
-     "shell.execute_reply": "2023-07-19T19:40:16.773536Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:16.701896Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -2720,13 +2635,6 @@
    "execution_count": 13,
    "id": "a8ba5f75-a935-4342-a867-931691e54e47",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:16.775317Z",
-     "iopub.status.busy": "2023-07-19T19:40:16.775019Z",
-     "iopub.status.idle": "2023-07-19T19:40:16.862604Z",
-     "shell.execute_reply": "2023-07-19T19:40:16.861893Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:16.775299Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -3238,13 +3146,6 @@
    "execution_count": 14,
    "id": "688be46d-8d22-45b8-9f4a-3c3df3bc2f05",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:16.863702Z",
-     "iopub.status.busy": "2023-07-19T19:40:16.863410Z",
-     "iopub.status.idle": "2023-07-19T19:40:18.270304Z",
-     "shell.execute_reply": "2023-07-19T19:40:18.269314Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:16.863684Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -3253,28 +3154,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-f04d0bc493074a22bffbf0a0c834c3e7.vega-embed {\n",
+       "  #altair-viz-2c6d5b97d08043a79b13a2d31efd9aa8.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-f04d0bc493074a22bffbf0a0c834c3e7.vega-embed details,\n",
-       "  #altair-viz-f04d0bc493074a22bffbf0a0c834c3e7.vega-embed details summary {\n",
+       "  #altair-viz-2c6d5b97d08043a79b13a2d31efd9aa8.vega-embed details,\n",
+       "  #altair-viz-2c6d5b97d08043a79b13a2d31efd9aa8.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-f04d0bc493074a22bffbf0a0c834c3e7\"></div>\n",
+       "<div id=\"altair-viz-2c6d5b97d08043a79b13a2d31efd9aa8\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-f04d0bc493074a22bffbf0a0c834c3e7\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-f04d0bc493074a22bffbf0a0c834c3e7\");\n",
+       "    if (outputDiv.id !== \"altair-viz-2c6d5b97d08043a79b13a2d31efd9aa8\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-2c6d5b97d08043a79b13a2d31efd9aa8\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -3310,12 +3211,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-42e7f5dbd0282babbfecc80c452dbb2f\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_6\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_5\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_7\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-0036197f12b0ff1e884b038f70b4f01d\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_7\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}, {\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_8\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#fcf8fa\", \"#faf1f6\", \"#f7eaf1\", \"#f4e3ec\", \"#f2dce8\", \"#efd5e3\", \"#eccedf\", \"#eac7da\", \"#e7c0d5\", \"#e4b8d1\", \"#e1b1cc\", \"#dfaac7\", \"#dca3c3\", \"#d99cbe\", \"#d795ba\", \"#d48eb5\", \"#d187b0\", \"#cf80ac\", \"#cc79a7\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_5['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_6['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_8\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-0036197f12b0ff1e884b038f70b4f01d\"}, \"resolve\": {\"scale\": {\"color\": \"independent\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_8\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_6\", \"view_5\", \"view_7\", \"view_8\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_5\"]}, {\"name\": \"param_7\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_5\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, 0.0], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_6\", \"view_5\", \"view_7\", \"view_8\"]}, {\"name\": \"param_5\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 5.0, \"min\": 3.0, \"name\": \"minimum n_models\"}, \"value\": [{\"cutoff\": 3}], \"views\": [\"view_6\", \"view_5\", \"view_7\", \"view_8\"]}, {\"name\": \"param_6\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 3.7295772137298258, \"min\": 0.0, \"name\": \"minimum max of escape at site\"}, \"value\": [{\"cutoff\": 0.0}], \"views\": [\"view_6\", \"view_5\", \"view_7\", \"view_8\"]}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-42e7f5dbd0282babbfecc80c452dbb2f\": [{\"site\": \"1\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"_stat_site_order\": 2}], \"data-0036197f12b0ff1e884b038f70b4f01d\": [{\"site\": \"1\", \"mutant\": \"C\", \"escape\": 2.4639455131088055, \"epitope\": \"epitope 1\", \"A 0\": 2.6458941130666562, \"A 1\": 2.236088976951976, \"A 2\": 2.3303348210038743, \"B 0\": null, \"B 1\": 2.5975562052137366, \"n_models\": 4.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 3.6192709663506637, \"epitope\": \"epitope 1\", \"A 0\": 3.89177300078208, \"A 1\": null, \"A 2\": 3.6192709663506637, \"B 0\": 3.125585310463836, \"B 1\": null, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 0.3834415188257777, \"epitope\": \"epitope 1\", \"A 0\": 0.3834415188257777, \"A 1\": 0.9355390708060318, \"A 2\": 0.26682727510286663, \"B 0\": 0.05146720330082988, \"B 1\": 0.9031785237401092, \"n_models\": 5.0}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 0.029876210878566956, \"epitope\": \"epitope 1\", \"A 0\": null, \"A 1\": 0.3132735169322751, \"A 2\": null, \"B 0\": 0.029876210878566956, \"B 1\": 0.005159148556627802, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 0.5135781212657464, \"epitope\": \"epitope 1\", \"A 0\": 0.925596638292661, \"A 1\": 0.44345289377955666, \"A 2\": 0.5135781212657464, \"B 0\": 0.6491440476147607, \"B 1\": 0.3614963440850427, \"n_models\": 5.0}, {\"site\": \"1\", \"mutant\": \"C\", \"escape\": 0.3006146806669343, \"epitope\": \"epitope 2\", \"A 0\": 0.4375872112626925, \"A 1\": 0.3965807272960261, \"A 2\": 0.2046486340378425, \"B 0\": null, \"B 1\": 0.14146417361702357, \"n_models\": 4.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 0.29965467367452314, \"epitope\": \"epitope 2\", \"A 0\": 0.9636627605010293, \"A 1\": null, \"A 2\": 0.29965467367452314, \"B 0\": 0.20724287813818676, \"B 1\": null, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 3.132963104392461, \"epitope\": \"epitope 2\", \"A 0\": 3.2917250380826646, \"A 1\": 3.346310916686017, \"A 2\": 3.121133832769295, \"B 0\": 2.9408098436506362, \"B 1\": 3.132963104392461, \"n_models\": 5.0}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 2.0245481595728716, \"epitope\": \"epitope 2\", \"A 0\": null, \"A 1\": 2.0245481595728716, \"A 2\": null, \"B 0\": 1.956833224394711, \"B 1\": 2.07235649126018, \"n_models\": 3.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 3.7295772137298258, \"epitope\": \"epitope 2\", \"A 0\": 3.571036058197887, \"A 1\": 3.7295772137298258, \"A 2\": 3.6844398656469153, \"B 0\": 3.7784872826479754, \"B 1\": 4.104131938247697, \"n_models\": 5.0}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null}], \"data-a7d600054b448517d77aab4449a3c18a\": [{\"site\": \"1\", \"wildtype\": \"M\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"wildtype\": \"G\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"wildtype\": \"A\", \"_stat_site_order\": 2}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-42e7f5dbd0282babbfecc80c452dbb2f\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_6\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_5\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_9\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-b367b4916fe032dae7f5c728ade839ae\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_7\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}, {\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_8\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.7295772137298258, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#fcf8fa\", \"#faf1f6\", \"#f7eaf1\", \"#f4e3ec\", \"#f2dce8\", \"#efd5e3\", \"#eccedf\", \"#eac7da\", \"#e7c0d5\", \"#e4b8d1\", \"#e1b1cc\", \"#dfaac7\", \"#dca3c3\", \"#d99cbe\", \"#d795ba\", \"#d48eb5\", \"#d187b0\", \"#cf80ac\", \"#cc79a7\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"A 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"A 2\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 0\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"B 1\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['A 0']),datum['A 0'],NaN)\", \"as\": \"A 0\"}, {\"calculate\": \"if(isFinite(datum['A 1']),datum['A 1'],NaN)\", \"as\": \"A 1\"}, {\"calculate\": \"if(isFinite(datum['A 2']),datum['A 2'],NaN)\", \"as\": \"A 2\"}, {\"calculate\": \"if(isFinite(datum['B 0']),datum['B 0'],NaN)\", \"as\": \"B 0\"}, {\"calculate\": \"if(isFinite(datum['B 1']),datum['B 1'],NaN)\", \"as\": \"B 1\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_6 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_7 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_8 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_10\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-b367b4916fe032dae7f5c728ade839ae\"}, \"resolve\": {\"scale\": {\"color\": \"independent\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_10\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_6\", \"view_5\", \"view_7\", \"view_8\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_5\"]}, {\"name\": \"param_9\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_5\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, 0.029876210878566956], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_6\", \"view_5\", \"view_7\", \"view_8\"]}, {\"name\": \"param_6\", \"bind\": {\"input\": \"range\", \"max\": 5.0, \"min\": 3.0, \"name\": \"minimum n_models\"}, \"value\": 3}, {\"name\": \"param_7\", \"bind\": {\"input\": \"range\", \"max\": 0.4126373948474744, \"min\": 0.05804678316119469, \"name\": \"maximum escape_std\"}, \"value\": 0.4126373948474744}, {\"name\": \"param_8\", \"bind\": {\"input\": \"range\", \"max\": 3.7295772137298258, \"min\": 0.029876210878566956, \"name\": \"minimum max of escape at site\"}, \"value\": 0.029876210878566956}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-42e7f5dbd0282babbfecc80c452dbb2f\": [{\"site\": \"1\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"_stat_site_order\": 2}], \"data-b367b4916fe032dae7f5c728ade839ae\": [{\"site\": \"1\", \"mutant\": \"C\", \"escape\": 2.4639455131088055, \"epitope\": \"epitope 1\", \"A 0\": 2.6458941130666562, \"A 1\": 2.236088976951976, \"A 2\": 2.3303348210038743, \"B 0\": null, \"B 1\": 2.5975562052137366, \"n_models\": 4.0, \"escape_std\": 0.2001671331113208}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 3.6192709663506637, \"epitope\": \"epitope 1\", \"A 0\": 3.89177300078208, \"A 1\": null, \"A 2\": 3.6192709663506637, \"B 0\": 3.125585310463836, \"B 1\": null, \"n_models\": 3.0, \"escape_std\": 0.3883783512660632}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 0.3834415188257777, \"epitope\": \"epitope 1\", \"A 0\": 0.3834415188257777, \"A 1\": 0.9355390708060318, \"A 2\": 0.26682727510286663, \"B 0\": 0.05146720330082988, \"B 1\": 0.9031785237401092, \"n_models\": 5.0, \"escape_std\": 0.39403584052427915}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 0.029876210878566956, \"epitope\": \"epitope 1\", \"A 0\": null, \"A 1\": 0.3132735169322751, \"A 2\": null, \"B 0\": 0.029876210878566956, \"B 1\": 0.005159148556627802, \"n_models\": 3.0, \"escape_std\": 0.1712013581760037}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 0.5135781212657464, \"epitope\": \"epitope 1\", \"A 0\": 0.925596638292661, \"A 1\": 0.44345289377955666, \"A 2\": 0.5135781212657464, \"B 0\": 0.6491440476147607, \"B 1\": 0.3614963440850427, \"n_models\": 5.0, \"escape_std\": 0.22079951184059773}, {\"site\": \"1\", \"mutant\": \"C\", \"escape\": 0.3006146806669343, \"epitope\": \"epitope 2\", \"A 0\": 0.4375872112626925, \"A 1\": 0.3965807272960261, \"A 2\": 0.2046486340378425, \"B 0\": null, \"B 1\": 0.14146417361702357, \"n_models\": 4.0, \"escape_std\": 0.14420628347773592}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 0.29965467367452314, \"epitope\": \"epitope 2\", \"A 0\": 0.9636627605010293, \"A 1\": null, \"A 2\": 0.29965467367452314, \"B 0\": 0.20724287813818676, \"B 1\": null, \"n_models\": 3.0, \"escape_std\": 0.4126373948474744}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 3.132963104392461, \"epitope\": \"epitope 2\", \"A 0\": 3.2917250380826646, \"A 1\": 3.346310916686017, \"A 2\": 3.121133832769295, \"B 0\": 2.9408098436506362, \"B 1\": 3.132963104392461, \"n_models\": 5.0, \"escape_std\": 0.15979056283813148}, {\"site\": \"4\", \"mutant\": \"L\", \"escape\": 2.0245481595728716, \"epitope\": \"epitope 2\", \"A 0\": null, \"A 1\": 2.0245481595728716, \"A 2\": null, \"B 0\": 1.956833224394711, \"B 1\": 2.07235649126018, \"n_models\": 3.0, \"escape_std\": 0.05804678316119469}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 3.7295772137298258, \"epitope\": \"epitope 2\", \"A 0\": 3.571036058197887, \"A 1\": 3.7295772137298258, \"A 2\": 3.6844398656469153, \"B 0\": 3.7784872826479754, \"B 1\": 4.104131938247697, \"n_models\": 5.0, \"escape_std\": 0.2001217829541086}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"A 0\": 0.0, \"A 1\": 0.0, \"A 2\": 0.0, \"B 0\": 0.0, \"B 1\": 0.0, \"n_models\": null, \"escape_std\": null}], \"data-a7d600054b448517d77aab4449a3c18a\": [{\"site\": \"1\", \"wildtype\": \"M\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"wildtype\": \"G\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"wildtype\": \"A\", \"_stat_site_order\": 2}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -3346,13 +3247,6 @@
    "execution_count": 15,
    "id": "17b2ad0d-0399-4b0d-8282-3400a998d3ef",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:18.271601Z",
-     "iopub.status.busy": "2023-07-19T19:40:18.271384Z",
-     "iopub.status.idle": "2023-07-19T19:40:18.325278Z",
-     "shell.execute_reply": "2023-07-19T19:40:18.324489Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:18.271584Z"
-    },
     "tags": []
    },
    "outputs": [],
@@ -3364,15 +3258,7 @@
    "cell_type": "code",
    "execution_count": 16,
    "id": "d21637c6-ebb8-481b-9a9e-9c313b4a90e3",
-   "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:18.326490Z",
-     "iopub.status.busy": "2023-07-19T19:40:18.326199Z",
-     "iopub.status.idle": "2023-07-19T19:40:18.367369Z",
-     "shell.execute_reply": "2023-07-19T19:40:18.366665Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:18.326472Z"
-    }
-   },
+   "metadata": {},
    "outputs": [
     {
      "data": {
@@ -3446,13 +3332,6 @@
    "execution_count": 17,
    "id": "c9cd79cc-295a-461c-bcf0-adb7e57e12ca",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:18.368387Z",
-     "iopub.status.busy": "2023-07-19T19:40:18.368204Z",
-     "iopub.status.idle": "2023-07-19T19:40:18.474072Z",
-     "shell.execute_reply": "2023-07-19T19:40:18.473437Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:18.368371Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -3461,28 +3340,28 @@
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-747641a11e704f77a57e7dddf3415eae.vega-embed {\n",
+       "  #altair-viz-572859ce9e194cc6914f33325f928c95.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-747641a11e704f77a57e7dddf3415eae.vega-embed details,\n",
-       "  #altair-viz-747641a11e704f77a57e7dddf3415eae.vega-embed details summary {\n",
+       "  #altair-viz-572859ce9e194cc6914f33325f928c95.vega-embed details,\n",
+       "  #altair-viz-572859ce9e194cc6914f33325f928c95.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-747641a11e704f77a57e7dddf3415eae\"></div>\n",
+       "<div id=\"altair-viz-572859ce9e194cc6914f33325f928c95\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-747641a11e704f77a57e7dddf3415eae\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-747641a11e704f77a57e7dddf3415eae\");\n",
+       "    if (outputDiv.id !== \"altair-viz-572859ce9e194cc6914f33325f928c95\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-572859ce9e194cc6914f33325f928c95\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -3518,12 +3397,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"labelLimit\": 500}}, \"data\": {\"name\": \"data-d70d59738f3d8e2ada1ce980ba47c0fb\"}, \"mark\": {\"type\": \"rect\", \"stroke\": \"black\"}, \"encoding\": {\"color\": {\"field\": \"r2\", \"scale\": {\"domain\": [0, 1], \"scheme\": \"yellowgreenblue\"}, \"type\": \"quantitative\"}, \"facet\": {\"columns\": 3, \"field\": \"epitope\", \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"r\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"r2\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"library_1\", \"type\": \"nominal\"}, {\"field\": \"replicate_1\", \"type\": \"quantitative\"}, {\"field\": \"library_2\", \"type\": \"nominal\"}, {\"field\": \"replicate_2\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_label_1\", \"title\": null, \"type\": \"nominal\"}, \"y\": {\"field\": \"_label_2\", \"title\": null, \"type\": \"nominal\"}}, \"height\": {\"step\": 15}, \"width\": {\"step\": 15}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-d70d59738f3d8e2ada1ce980ba47c0fb\": [{\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"labelLimit\": 500}}, \"data\": {\"name\": \"data-d70d59738f3d8e2ada1ce980ba47c0fb\"}, \"mark\": {\"type\": \"rect\", \"stroke\": \"black\"}, \"encoding\": {\"color\": {\"field\": \"r2\", \"scale\": {\"domain\": [0, 1], \"scheme\": \"yellowgreenblue\"}, \"type\": \"quantitative\"}, \"facet\": {\"columns\": 3, \"field\": \"epitope\", \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"r\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"r2\", \"format\": \".3f\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"library_1\", \"type\": \"nominal\"}, {\"field\": \"replicate_1\", \"type\": \"quantitative\"}, {\"field\": \"library_2\", \"type\": \"nominal\"}, {\"field\": \"replicate_2\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_label_1\", \"title\": null, \"type\": \"nominal\"}, \"y\": {\"field\": \"_label_2\", \"title\": null, \"type\": \"nominal\"}}, \"height\": {\"step\": 15}, \"width\": {\"step\": 15}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-d70d59738f3d8e2ada1ce980ba47c0fb\": [{\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"1\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}, {\"r\": 1.0, \"r2\": 1.0, \"epitope\": \"2\", \"library_1\": \"A\", \"replicate_1\": 0, \"library_2\": \"A\", \"replicate_2\": 0, \"_label_1\": \"A-0\", \"_label_2\": \"A-0\"}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -3546,13 +3425,6 @@
    "execution_count": 18,
    "id": "8f31165f-71de-44d5-89ab-8aac85a41300",
    "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:18.475169Z",
-     "iopub.status.busy": "2023-07-19T19:40:18.474976Z",
-     "iopub.status.idle": "2023-07-19T19:40:18.488034Z",
-     "shell.execute_reply": "2023-07-19T19:40:18.487397Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:18.475152Z"
-    },
     "tags": []
    },
    "outputs": [
@@ -3621,43 +3493,35 @@
    "cell_type": "code",
    "execution_count": 19,
    "id": "e45b077a-e0f5-4d8a-a0a4-80eaf98cbe69",
-   "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:18.489154Z",
-     "iopub.status.busy": "2023-07-19T19:40:18.488854Z",
-     "iopub.status.idle": "2023-07-19T19:40:18.563482Z",
-     "shell.execute_reply": "2023-07-19T19:40:18.562766Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:18.489129Z"
-    }
-   },
+   "metadata": {},
    "outputs": [
     {
      "data": {
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-3e3101d897bd45dbaf4c7abe6147ae8e.vega-embed {\n",
+       "  #altair-viz-eb84d7ba7468497d9b5c0a4f094a18fa.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-3e3101d897bd45dbaf4c7abe6147ae8e.vega-embed details,\n",
-       "  #altair-viz-3e3101d897bd45dbaf4c7abe6147ae8e.vega-embed details summary {\n",
+       "  #altair-viz-eb84d7ba7468497d9b5c0a4f094a18fa.vega-embed details,\n",
+       "  #altair-viz-eb84d7ba7468497d9b5c0a4f094a18fa.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-3e3101d897bd45dbaf4c7abe6147ae8e\"></div>\n",
+       "<div id=\"altair-viz-eb84d7ba7468497d9b5c0a4f094a18fa\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-3e3101d897bd45dbaf4c7abe6147ae8e\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-3e3101d897bd45dbaf4c7abe6147ae8e\");\n",
+       "    if (outputDiv.id !== \"altair-viz-eb84d7ba7468497d9b5c0a4f094a18fa\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-eb84d7ba7468497d9b5c0a4f094a18fa\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -3693,12 +3557,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"layer\": [{\"mark\": {\"type\": \"bar\", \"size\": 18.75}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"1\", \"2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"activity_mean\", \"title\": \"activity_mean\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}, {\"mark\": {\"type\": \"rule\", \"size\": 2}, \"encoding\": {\"color\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_lower\", \"type\": \"quantitative\"}, \"x2\": {\"field\": \"_upper\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}], \"data\": {\"name\": \"data-b6ba616a701446645dcd238a30c2556a\"}, \"height\": {\"step\": 25}, \"width\": 110, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-b6ba616a701446645dcd238a30c2556a\": [{\"epitope\": \"1\", \"activity_mean\": 2.5488135039273248, \"activity_median\": 2.5488135039273248, \"activity_std\": null, \"_lower\": null, \"_upper\": null}, {\"epitope\": \"2\", \"activity_mean\": 1.7151893663724196, \"activity_median\": 1.7151893663724196, \"activity_std\": null, \"_lower\": null, \"_upper\": null}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false}}, \"layer\": [{\"mark\": {\"type\": \"bar\", \"size\": 18.75}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": null, \"scale\": {\"domain\": [\"1\", \"2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"activity_mean\", \"title\": \"activity_mean\", \"type\": \"quantitative\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}, {\"mark\": {\"type\": \"rule\", \"size\": 2}, \"encoding\": {\"color\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"activity_mean\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_median\", \"format\": \".2f\", \"type\": \"quantitative\"}, {\"field\": \"activity_std\", \"format\": \".2f\", \"type\": \"quantitative\"}], \"x\": {\"field\": \"_lower\", \"type\": \"quantitative\"}, \"x2\": {\"field\": \"_upper\"}, \"y\": {\"field\": \"epitope\", \"sort\": [\"1\", \"2\"], \"type\": \"nominal\"}}}], \"data\": {\"name\": \"data-b6ba616a701446645dcd238a30c2556a\"}, \"height\": {\"step\": 25}, \"width\": 110, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-b6ba616a701446645dcd238a30c2556a\": [{\"epitope\": \"1\", \"activity_mean\": 2.5488135039273248, \"activity_median\": 2.5488135039273248, \"activity_std\": null, \"_lower\": null, \"_upper\": null}, {\"epitope\": \"2\", \"activity_mean\": 1.7151893663724196, \"activity_median\": 1.7151893663724196, \"activity_std\": null, \"_lower\": null, \"_upper\": null}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -3720,15 +3584,7 @@
    "cell_type": "code",
    "execution_count": 20,
    "id": "e12a5c30-7179-4279-9e8c-031b04ed8d22",
-   "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:18.566961Z",
-     "iopub.status.busy": "2023-07-19T19:40:18.566657Z",
-     "iopub.status.idle": "2023-07-19T19:40:18.598467Z",
-     "shell.execute_reply": "2023-07-19T19:40:18.597557Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:18.566943Z"
-    }
-   },
+   "metadata": {},
    "outputs": [
     {
      "data": {
@@ -3916,43 +3772,35 @@
    "cell_type": "code",
    "execution_count": 21,
    "id": "0a899811-e216-4c47-97c5-c412162f9500",
-   "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:18.599808Z",
-     "iopub.status.busy": "2023-07-19T19:40:18.599424Z",
-     "iopub.status.idle": "2023-07-19T19:40:19.957972Z",
-     "shell.execute_reply": "2023-07-19T19:40:19.957274Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:18.599781Z"
-    }
-   },
+   "metadata": {},
    "outputs": [
     {
      "data": {
       "text/html": [
        "\n",
        "<style>\n",
-       "  #altair-viz-421cc2f06f314d8d8ea9f413503c227a.vega-embed {\n",
+       "  #altair-viz-184e9655919144b5a6b0c51d38712232.vega-embed {\n",
        "    width: 100%;\n",
        "    display: flex;\n",
        "  }\n",
        "\n",
-       "  #altair-viz-421cc2f06f314d8d8ea9f413503c227a.vega-embed details,\n",
-       "  #altair-viz-421cc2f06f314d8d8ea9f413503c227a.vega-embed details summary {\n",
+       "  #altair-viz-184e9655919144b5a6b0c51d38712232.vega-embed details,\n",
+       "  #altair-viz-184e9655919144b5a6b0c51d38712232.vega-embed details summary {\n",
        "    position: relative;\n",
        "  }\n",
        "</style>\n",
-       "<div id=\"altair-viz-421cc2f06f314d8d8ea9f413503c227a\"></div>\n",
+       "<div id=\"altair-viz-184e9655919144b5a6b0c51d38712232\"></div>\n",
        "<script type=\"text/javascript\">\n",
        "  var VEGA_DEBUG = (typeof VEGA_DEBUG == \"undefined\") ? {} : VEGA_DEBUG;\n",
        "  (function(spec, embedOpt){\n",
        "    let outputDiv = document.currentScript.previousElementSibling;\n",
-       "    if (outputDiv.id !== \"altair-viz-421cc2f06f314d8d8ea9f413503c227a\") {\n",
-       "      outputDiv = document.getElementById(\"altair-viz-421cc2f06f314d8d8ea9f413503c227a\");\n",
+       "    if (outputDiv.id !== \"altair-viz-184e9655919144b5a6b0c51d38712232\") {\n",
+       "      outputDiv = document.getElementById(\"altair-viz-184e9655919144b5a6b0c51d38712232\");\n",
        "    }\n",
        "    const paths = {\n",
        "      \"vega\": \"https://cdn.jsdelivr.net/npm/vega@5?noext\",\n",
        "      \"vega-lib\": \"https://cdn.jsdelivr.net/npm/vega-lib?noext\",\n",
-       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.8.0?noext\",\n",
+       "      \"vega-lite\": \"https://cdn.jsdelivr.net/npm/vega-lite@5.16.3?noext\",\n",
        "      \"vega-embed\": \"https://cdn.jsdelivr.net/npm/vega-embed@6?noext\",\n",
        "    };\n",
        "\n",
@@ -3988,12 +3836,12 @@
        "      require([\"vega-embed\"], displayChart, err => showError(`Error loading script: ${err.message}`));\n",
        "    } else {\n",
        "      maybeLoadScript(\"vega\", \"5\")\n",
-       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.8.0\"))\n",
+       "        .then(() => maybeLoadScript(\"vega-lite\", \"5.16.3\"))\n",
        "        .then(() => maybeLoadScript(\"vega-embed\", \"6\"))\n",
        "        .catch(showError)\n",
        "        .then(() => displayChart(vegaEmbed));\n",
        "    }\n",
-       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-42e7f5dbd0282babbfecc80c452dbb2f\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_10\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_9\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_11\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-372c3ef62d953b98ae254299b74509e7\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_11\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.89177300078208, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}, {\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_12\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": 3.89177300078208, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#fcf8fa\", \"#faf1f6\", \"#f7eaf1\", \"#f4e3ec\", \"#f2dce8\", \"#efd5e3\", \"#eccedf\", \"#eac7da\", \"#e7c0d5\", \"#e4b8d1\", \"#e1b1cc\", \"#dfaac7\", \"#dca3c3\", \"#d99cbe\", \"#d795ba\", \"#d48eb5\", \"#d187b0\", \"#cf80ac\", \"#cc79a7\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-a7d600054b448517d77aab4449a3c18a\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"((datum['n_models'] >= (param_9['cutoff'] - 1e-06)) || (!isFinite(datum['n_models'])))\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"((datum['_stat_site_max'] >= (param_10['cutoff'] - 1e-06)) || (!isFinite(datum['_stat_site_max'])))\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_12\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-372c3ef62d953b98ae254299b74509e7\"}, \"resolve\": {\"scale\": {\"color\": \"independent\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_12\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_10\", \"view_9\", \"view_11\", \"view_12\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_9\"]}, {\"name\": \"param_11\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_9\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, 0.0], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_10\", \"view_9\", \"view_11\", \"view_12\"]}, {\"name\": \"param_9\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 1.0, \"min\": 1.0, \"name\": \"minimum n_models\"}, \"value\": [{\"cutoff\": 1}], \"views\": [\"view_10\", \"view_9\", \"view_11\", \"view_12\"]}, {\"name\": \"param_10\", \"select\": {\"type\": \"point\", \"fields\": [\"cutoff\"]}, \"bind\": {\"input\": \"range\", \"max\": 3.89177300078208, \"min\": 0.0, \"name\": \"minimum max of escape at site\"}, \"value\": [{\"cutoff\": 0.0}], \"views\": [\"view_10\", \"view_9\", \"view_11\", \"view_12\"]}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.8.0.json\", \"datasets\": {\"data-42e7f5dbd0282babbfecc80c452dbb2f\": [{\"site\": \"1\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"_stat_site_order\": 2}], \"data-372c3ef62d953b98ae254299b74509e7\": [{\"site\": \"1\", \"mutant\": \"C\", \"escape\": 2.6458941130666562, \"epitope\": \"epitope 1\", \"\": 2.6458941130666562, \"n_models\": 1.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 3.89177300078208, \"epitope\": \"epitope 1\", \"\": 3.89177300078208, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 0.3834415188257777, \"epitope\": \"epitope 1\", \"\": 0.3834415188257777, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 0.925596638292661, \"epitope\": \"epitope 1\", \"\": 0.925596638292661, \"n_models\": 1.0}, {\"site\": \"1\", \"mutant\": \"C\", \"escape\": 0.4375872112626925, \"epitope\": \"epitope 2\", \"\": 0.4375872112626925, \"n_models\": 1.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 0.9636627605010293, \"epitope\": \"epitope 2\", \"\": 0.9636627605010293, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 3.2917250380826646, \"epitope\": \"epitope 2\", \"\": 3.2917250380826646, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 3.571036058197887, \"epitope\": \"epitope 2\", \"\": 3.571036058197887, \"n_models\": 1.0}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"\": 0.0, \"n_models\": null}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"\": 0.0, \"n_models\": null}], \"data-a7d600054b448517d77aab4449a3c18a\": [{\"site\": \"1\", \"wildtype\": \"M\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"wildtype\": \"G\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"wildtype\": \"A\", \"_stat_site_order\": 2}]}}, {\"mode\": \"vega-lite\"});\n",
+       "  })({\"config\": {\"view\": {\"continuousWidth\": 300, \"continuousHeight\": 300}, \"axis\": {\"grid\": false, \"labelOverlap\": \"parity\"}, \"padding\": 10}, \"vconcat\": [{\"data\": {\"name\": \"data-42e7f5dbd0282babbfecc80c452dbb2f\"}, \"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"gray\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}}, \"height\": 11, \"name\": \"view_10\", \"title\": \"site zoom bar\", \"width\": 500}, {\"layer\": [{\"mark\": {\"type\": \"line\", \"opacity\": 0.7, \"size\": 1}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"escape_std\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"name\": \"view_9\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"escape_std\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}, {\"calculate\": \"true\", \"as\": \"_stat_show_line\"}, {\"filter\": {\"param\": \"param_14\"}}]}, {\"mark\": {\"type\": \"circle\", \"opacity\": 0.7}, \"encoding\": {\"color\": {\"field\": \"epitope\", \"legend\": {\"orient\": \"left\"}, \"scale\": {\"domain\": [\"epitope 1\", \"epitope 2\"], \"range\": [\"#0072B2\", \"#CC79A7\"]}, \"type\": \"nominal\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"field\": \"_stat_site_val\", \"format\": \".3g\", \"title\": \"site escape\", \"type\": \"quantitative\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"escape_std\", \"type\": \"nominal\"}], \"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"_stat_site_val\", \"scale\": {\"zero\": true}, \"title\": \"site escape\", \"type\": \"quantitative\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"((datum.wildtype !== datum.mutant) && (!datum['_stat_hide']))\"}, {\"aggregate\": [{\"op\": \"sum\", \"field\": \"_stat\", \"as\": \"_stat_sum\"}, {\"op\": \"mean\", \"field\": \"_stat\", \"as\": \"_stat_mean\"}, {\"op\": \"max\", \"field\": \"_stat\", \"as\": \"_stat_max\"}, {\"op\": \"min\", \"field\": \"_stat\", \"as\": \"_stat_min\"}], \"groupby\": [\"site\", \"wildtype\", \"escape_std\", \"_stat_site_order\", \"epitope\"]}, {\"fold\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"as\": [\"_stat_site_stat\", \"_stat_site_val\"]}, {\"filter\": {\"param\": \"site_stat\"}}]}], \"data\": {\"name\": \"data-372c3ef62d953b98ae254299b74509e7\"}, \"height\": 100, \"width\": 690}, {\"vconcat\": [{\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_11\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": NaN, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#f2f8fb\", \"#e4f0f7\", \"#d7e9f3\", \"#c9e1ef\", \"#bcdaeb\", \"#aed2e7\", \"#a1cbe3\", \"#94c4df\", \"#86bcdb\", \"#79b5d6\", \"#6badd2\", \"#5ea6ce\", \"#519fca\", \"#4397c6\", \"#3690c2\", \"#2888be\", \"#1b81ba\", \"#0d79b6\", \"#0072b2\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": false, \"ticks\": false, \"title\": null}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 1\", \"anchor\": \"middle\", \"color\": \"#0072B2\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 1')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}, {\"layer\": [{\"mark\": {\"type\": \"rect\", \"color\": \"#E0E0E0\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"name\": \"view_12\", \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"impute\": \"_stat_dummy\", \"key\": \"mutant\", \"groupby\": [\"site\"], \"keyvals\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"value\": null}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"value\": \"silver\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"datum['_stat_hide']\"}]}, {\"mark\": {\"type\": \"rect\"}, \"encoding\": {\"color\": {\"field\": \"_stat\", \"legend\": {\"gradientLength\": 100, \"gradientStrokeColor\": \"black\", \"gradientStrokeWidth\": 0.5, \"orient\": \"left\", \"title\": \"escape\", \"titleOrient\": \"left\"}, \"scale\": {\"clamp\": true, \"domainMax\": NaN, \"domainMid\": 0, \"domainMin\": {\"expr\": \"floor_at_zero.floor\"}, \"nice\": false, \"range\": [\"#e69f00\", \"#e7a40d\", \"#e9a91b\", \"#eaae28\", \"#ebb336\", \"#edb843\", \"#eebd51\", \"#efc25e\", \"#f1c76b\", \"#f2cc79\", \"#f3d286\", \"#f4d794\", \"#f6dca1\", \"#f7e1ae\", \"#f8e6bc\", \"#faebc9\", \"#fbf0d7\", \"#fcf5e4\", \"#fefaf2\", \"#ffffff\", \"#fcf8fa\", \"#faf1f6\", \"#f7eaf1\", \"#f4e3ec\", \"#f2dce8\", \"#efd5e3\", \"#eccedf\", \"#eac7da\", \"#e7c0d5\", \"#e4b8d1\", \"#e1b1cc\", \"#dfaac7\", \"#dca3c3\", \"#d99cbe\", \"#d795ba\", \"#d48eb5\", \"#d187b0\", \"#cf80ac\", \"#cc79a7\"], \"type\": \"linear\", \"zero\": true}, \"type\": \"quantitative\"}, \"stroke\": {\"value\": \"black\"}, \"tooltip\": [{\"field\": \"site\", \"type\": \"nominal\"}, {\"field\": \"wildtype\", \"type\": \"nominal\"}, {\"field\": \"mutant\", \"type\": \"nominal\"}, {\"field\": \"escape\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"epitope\", \"type\": \"nominal\"}, {\"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"n_models\", \"format\": \".3g\", \"type\": \"quantitative\"}, {\"field\": \"escape_std\", \"format\": \".3g\", \"type\": \"quantitative\"}], \"x\": {\"axis\": {\"labels\": true, \"ticks\": true, \"title\": \"site\"}, \"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"title\": {\"text\": \"epitope 2\", \"anchor\": \"middle\", \"color\": \"#CC79A7\", \"orient\": \"left\"}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum['epitope'] === 'epitope 2')\"}, {\"filter\": \"(!datum['_stat_hide'])\"}]}, {\"mark\": {\"type\": \"text\", \"color\": \"black\", \"text\": \"x\"}, \"encoding\": {\"x\": {\"field\": \"site\", \"sort\": {\"field\": \"_stat_site_order\", \"order\": \"ascending\"}, \"type\": \"ordinal\"}, \"y\": {\"field\": \"mutant\", \"scale\": {\"domain\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"]}, \"sort\": [\"R\", \"K\", \"H\", \"D\", \"E\", \"Q\", \"N\", \"S\", \"T\", \"Y\", \"W\", \"F\", \"A\", \"I\", \"L\", \"M\", \"V\", \"G\", \"P\", \"C\"], \"title\": null, \"type\": \"nominal\"}}, \"transform\": [{\"lookup\": \"site\", \"from\": {\"data\": {\"name\": \"data-afcf848cff8c29597107b52a4ea80b52\"}, \"key\": \"site\", \"fields\": [\"wildtype\", \"escape_std\", \"_stat_site_order\"]}}, {\"calculate\": \"if(isFinite(datum['escape']),datum['escape'],NaN)\", \"as\": \"escape\"}, {\"calculate\": \"if(isFinite(datum['']),datum[''],NaN)\", \"as\": \"\"}, {\"calculate\": \"if(isFinite(datum['n_models']),datum['n_models'],NaN)\", \"as\": \"n_models\"}, {\"calculate\": \"if(isFinite(datum['escape_std']),datum['escape_std'],NaN)\", \"as\": \"escape_std\"}, {\"calculate\": \"max(datum['escape'],floor_at_zero['floor'])\", \"as\": \"_stat\"}, {\"calculate\": \"false\", \"as\": \"_stat_hide\"}, {\"filter\": \"(((datum['n_models'] >= (param_11 - 1e-06)) || (!isFinite(datum['n_models']))) || datum['_stat_hide'])\"}, {\"filter\": \"(((datum['escape_std'] <= (param_12 + 1e-06)) || (!isFinite(datum['escape_std']))) || datum['_stat_hide'])\"}, {\"calculate\": \"if(datum['_stat_hide'],0.0,datum['_stat'])\", \"as\": \"_stat_not_hidden\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_hidden\", \"as\": \"_stat_site_max\"}], \"groupby\": [\"site\"]}, {\"filter\": \"(((datum['_stat_site_max'] >= (param_13 - 1e-06)) || (!isFinite(datum['_stat_site_max']))) || datum['_stat_hide'])\"}, {\"calculate\": \"(datum.wildtype !== datum.mutant)\", \"as\": \"_stat_not_wildtype\"}, {\"joinaggregate\": [{\"op\": \"max\", \"field\": \"_stat_not_wildtype\", \"as\": \"_stat_site_has_non_wildtype\"}], \"groupby\": [\"site\"]}, {\"filter\": \"datum['_stat_site_has_non_wildtype']\"}, {\"filter\": {\"param\": \"param_15\"}}, {\"filter\": \"(datum.wildtype === datum.mutant)\"}]}], \"height\": {\"step\": 11}, \"width\": {\"step\": 11}}], \"data\": {\"name\": \"data-372c3ef62d953b98ae254299b74509e7\"}, \"resolve\": {\"scale\": {\"color\": \"independent\", \"x\": \"shared\"}}, \"spacing\": 10}], \"params\": [{\"name\": \"param_15\", \"select\": {\"type\": \"interval\", \"encodings\": [\"x\"], \"mark\": {\"stroke\": \"black\", \"strokeWidth\": 2}}, \"views\": [\"view_10\", \"view_9\", \"view_11\", \"view_12\"]}, {\"name\": \"site_stat\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_site_stat\"]}, \"bind\": {\"input\": \"radio\", \"options\": [\"_stat_sum\", \"_stat_mean\", \"_stat_max\", \"_stat_min\"], \"labels\": [\"sum\", \"mean\", \"max\", \"min\"], \"name\": \"site escape statistic\"}, \"value\": [{\"_stat_site_stat\": \"_stat_sum\"}], \"views\": [\"view_9\"]}, {\"name\": \"param_14\", \"select\": {\"type\": \"point\", \"fields\": [\"_stat_show_line\"]}, \"bind\": {\"input\": \"radio\", \"options\": [true, false], \"labels\": [\"yes\", \"no\"], \"name\": \"show line on site plot\"}, \"value\": [{\"_stat_show_line\": true}], \"views\": [\"view_9\"]}, {\"name\": \"floor_at_zero\", \"select\": {\"type\": \"point\", \"fields\": [\"floor\"]}, \"bind\": {\"input\": \"radio\", \"options\": [0, NaN], \"labels\": [\"yes\", \"no\"], \"name\": \"floor escape at zero\"}, \"value\": [{\"floor\": 0}], \"views\": [\"view_10\", \"view_9\", \"view_11\", \"view_12\"]}, {\"name\": \"param_11\", \"bind\": {\"input\": \"range\", \"max\": 1.0, \"min\": 1.0, \"name\": \"minimum n_models\"}, \"value\": 1}, {\"name\": \"param_12\", \"bind\": {\"input\": \"range\", \"max\": NaN, \"min\": NaN, \"name\": \"maximum escape_std\"}, \"value\": NaN}, {\"name\": \"param_13\", \"bind\": {\"input\": \"range\", \"max\": NaN, \"min\": NaN, \"name\": \"minimum max of escape at site\"}, \"value\": NaN}, {\"name\": \"param_12\", \"bind\": {\"input\": \"range\", \"max\": NaN, \"min\": NaN, \"name\": \"maximum escape_std\"}, \"value\": NaN}, {\"name\": \"param_12\", \"bind\": {\"input\": \"range\", \"max\": NaN, \"min\": NaN, \"name\": \"maximum escape_std\"}, \"value\": NaN}, {\"name\": \"param_12\", \"bind\": {\"input\": \"range\", \"max\": NaN, \"min\": NaN, \"name\": \"maximum escape_std\"}, \"value\": NaN}], \"resolve\": {\"scale\": {\"color\": \"independent\"}}, \"$schema\": \"https://vega.github.io/schema/vega-lite/v5.16.3.json\", \"datasets\": {\"data-42e7f5dbd0282babbfecc80c452dbb2f\": [{\"site\": \"1\", \"_stat_site_order\": 0}, {\"site\": \"2\", \"_stat_site_order\": 1}, {\"site\": \"4\", \"_stat_site_order\": 2}], \"data-372c3ef62d953b98ae254299b74509e7\": [{\"site\": \"1\", \"mutant\": \"C\", \"escape\": 2.6458941130666562, \"epitope\": \"epitope 1\", \"\": 2.6458941130666562, \"n_models\": 1.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 3.89177300078208, \"epitope\": \"epitope 1\", \"\": 3.89177300078208, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 0.3834415188257777, \"epitope\": \"epitope 1\", \"\": 0.3834415188257777, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 0.925596638292661, \"epitope\": \"epitope 1\", \"\": 0.925596638292661, \"n_models\": 1.0}, {\"site\": \"1\", \"mutant\": \"C\", \"escape\": 0.4375872112626925, \"epitope\": \"epitope 2\", \"\": 0.4375872112626925, \"n_models\": 1.0}, {\"site\": \"2\", \"mutant\": \"A\", \"escape\": 0.9636627605010293, \"epitope\": \"epitope 2\", \"\": 0.9636627605010293, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"K\", \"escape\": 3.2917250380826646, \"epitope\": \"epitope 2\", \"\": 3.2917250380826646, \"n_models\": 1.0}, {\"site\": \"4\", \"mutant\": \"Q\", \"escape\": 3.571036058197887, \"epitope\": \"epitope 2\", \"\": 3.571036058197887, \"n_models\": 1.0}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 1\", \"\": 0.0, \"n_models\": null}, {\"site\": \"1\", \"mutant\": \"M\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"\": 0.0, \"n_models\": null}, {\"site\": \"2\", \"mutant\": \"G\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"\": 0.0, \"n_models\": null}, {\"site\": \"4\", \"mutant\": \"A\", \"escape\": 0.0, \"epitope\": \"epitope 2\", \"\": 0.0, \"n_models\": null}], \"data-afcf848cff8c29597107b52a4ea80b52\": [{\"site\": \"1\", \"wildtype\": \"M\", \"escape_std\": null, \"_stat_site_order\": 0}, {\"site\": \"2\", \"wildtype\": \"G\", \"escape_std\": null, \"_stat_site_order\": 1}, {\"site\": \"4\", \"wildtype\": \"A\", \"escape_std\": null, \"_stat_site_order\": 2}]}}, {\"mode\": \"vega-lite\"});\n",
        "</script>"
       ],
       "text/plain": [
@@ -4015,15 +3863,7 @@
    "cell_type": "code",
    "execution_count": 22,
    "id": "1eda7a75-87b0-4a40-800a-31d2a6f06c60",
-   "metadata": {
-    "execution": {
-     "iopub.execute_input": "2023-07-19T19:40:19.960686Z",
-     "iopub.status.busy": "2023-07-19T19:40:19.960158Z",
-     "iopub.status.idle": "2023-07-19T19:40:20.006991Z",
-     "shell.execute_reply": "2023-07-19T19:40:20.006277Z",
-     "shell.execute_reply.started": "2023-07-19T19:40:19.960650Z"
-    }
-   },
+   "metadata": {},
    "outputs": [
     {
      "data": {
@@ -4553,7 +4393,7 @@
    "name": "python",
    "nbconvert_exporter": "python",
    "pygments_lexer": "ipython3",
-   "version": "3.11.4"
+   "version": "3.11.7"
   }
  },
  "nbformat": 4,